{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Analysing the impact of the One Drug Database on OpenPrescribing\n",
    "\n",
    "February 2020\n",
    "\n",
    "The BSA publish the [Detailed Prescribing Information](https://www.nhsbsa.nhs.uk/prescription-data/prescribing-data/detailed-prescribing-information) dataset monthly, which contains the number of items prescribed of each presentation for each practice.  In 2020 they are changing the underlying database which produces this dataset.  This is called the [One Drug Database project](https://www.nhsbsa.nhs.uk/important-information-drug-data), and these changes will affect the Detailed Prescribing Information dataset that we use.\n",
    "\n",
    "We expect to be affected by two changes.\n",
    "\n",
    "## Change 1: BNF code changes\n",
    "\n",
    "There will be a rationalisation of BNF codes.  In particular:\n",
    "\n",
    "> BNF codes will change for products (drugs and appliances) where the pack size is currently shown as part of the naming convention.\n",
    "\n",
    "[1501 presentations](#Distribution-of-numbers-of-new-presentations-that-are-mapped-to) are affected by changed BNF codes.\n",
    "\n",
    "However, it looks like there has been a much larger rationalisation of BNF codes.\n",
    "\n",
    "Changes include:\n",
    "\n",
    "* [Old \"Liq Spec\" presentation disaggregated into \"oral solution\" and \"oral suspension\" presentations](#Old-\"Liq-Spec\"-presentation-disaggregated-into-\"oral-solution\"-and-\"oral-suspension\"-presentations)\n",
    "* [Old brandend presentation disaggregated into branded and generic presentations](#Old-brandend-presentation-disaggregated-into-branded-and-generic-presentations)\n",
    "* [Old presentation disaggregated into more accurately named presentations](#Old-presentation-disaggregated-into-more-accurately-named-presentations)\n",
    "* [Branded appliances into branded presentation and generic presentation in chapter 13](#Branded-appliances-into-branded-presentation-and-generic-presentation-in-chapter-13)\n",
    "* [An old version of a presentation is combined with the current version of the same](#An-old-version-of-a-presentation-is-combined-with-the-current-version-of-the-same)\n",
    "* [An \"Oral Soln\" presentation is combined with an \"Oral Susp\" presentation](#An-\"Oral-Soln\"-presentation-is-combined-with-an-\"Oral-Susp\"-presentation)\n",
    "* [Presentations of different flavour are combined](#Presentations-of-different-flavour-are-combined)\n",
    "* [Presentations of different dose size are combined](#Presentations-of-different-dose-size-are-combined)\n",
    "* [Branded presentations are combined into a generic presentation](#Branded-presentations-are-combined-into-a-generic-presentation)\n",
    "\n",
    "Presentations affected by changed BNF codes account for [1.3% of items and 1.4% of net_cost in November 2019](#Percentage-of-items-and-net_cost-that-are-affected-by-change-1).\n",
    "\n",
    "1% of presentations account for [55% of items](#Distribution-of-presentations-affected-by-change-1,-by-items) and [29% of net_cost](#Distribution-of-presentations-affected-by-change-1,-by-net_cost), and 10% of presentations account for [89% of items](#Distribution-of-presentations-affected-by-change-1,-by-items) and [82% of net_cost](#Distribution-of-presentations-affected-by-change-1,-by-net_cost).\n",
    "\n",
    "The 10 presentations most affected by changes in items are shown [here](#Top-10-presentations-affected-by-change-1,-by-items), and the 10 presentations most affected by changes in net_cost are shown [here](#Top-10-presentations-affected-by-change-1,-by-net_cost).\n",
    "\n",
    "## Change 2: special container quantity changes\n",
    "\n",
    "Some special container packs currently include the pack size in the drug name, and the quantity field represents the number of packs.  Once the ODD changes are applied:\n",
    "\n",
    "> the quantity will be represented as the total quantity (for example, the number of mls or gms), instead of the number of special container packs.\n",
    "\n",
    "Presentations affected by changed BNF codes account for [1.5% of items and 3.2% of net_cost in November 2019](#Percentage-of-items-and-net_cost-that-are-affected-by-change-2).\n",
    "\n",
    "1% of presentations account for [44% of items](#Distribution-of-presentations-affected-by-change-2,-by-items) and [31% of net_cost](#Distribution-of-presentations-affected-by-change-2,-by-net_cost), and 10% of presentations account for [87% of items](#Distribution-of-presentations-affected-by-change-2,-by-items) and [84% of net_cost](#Distribution-of-presentations-affected-by-change-2,-by-net_cost).\n",
    "\n",
    "The 10 presentations most affected by changes in items are shown [here](#Top-10-presentations-affected-by-change-2,-by-items), and the 10 presentations most affected by changes in net_cost are shown [here](#Top-10-presentations-affected-by-change-2,-by-net_cost)."
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Housekeeping"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Imports from the standard library\n",
    "import json\n",
    "from collections import Counter\n",
    "\n",
    "# Imports from third-party packages\n",
    "import pandas as pd\n",
    "from ebmdatalab import bq"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Ensure that DataFrames columns are not truncated\n",
    "pd.set_option('display.max_colwidth', -1)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Total items and net_cost for November 2019"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "\n",
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       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>items</th>\n",
       "      <th>net_cost</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>93549790</td>\n",
       "      <td>7.585725e+08</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "      items      net_cost\n",
       "0  93549790  7.585725e+08"
      ]
     },
     "execution_count": 3,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# Query the prescribing data in BigQuery for the total items and net_cost \n",
    "sql = \"\"\"\n",
    "SELECT\n",
    "    SUM(items) AS items,\n",
    "    SUM(net_cost_pence) / 100 AS net_cost\n",
    "FROM public_draft.prescribing\n",
    "WHERE month = '2019-11-01'\n",
    "\"\"\"\n",
    "\n",
    "df = bq.cached_read(sql, csv_path='../bq-cache/2019_11_items_and_spending.csv')\n",
    "df"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Save these off for later -- we'll want to see what proprtion the items and net_cost are affected by the changes\n",
    "total_items, total_net_cost = df.iloc[0]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Change 1: BNF code changes"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Affected presentations"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "\n",
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       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Current BNF Code</th>\n",
       "      <th>MDR: BNF Description</th>\n",
       "      <th>New BNF Code</th>\n",
       "      <th>dm+d: BNF Description</th>\n",
       "      <th>BNF Code Changed (Y/N)</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>0101010C0AAAAAA</td>\n",
       "      <td>Alum Hydrox_Cap 475mg</td>\n",
       "      <td>0101010C0AAAAAA</td>\n",
       "      <td>Aluminium hydroxide 475mg capsules</td>\n",
       "      <td>N</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>0101010C0AAACAC</td>\n",
       "      <td>Alum Hydrox_Oral Susp S/F</td>\n",
       "      <td>0101010C0AAACAC</td>\n",
       "      <td>Aluminium hydroxide oral suspension sugar free</td>\n",
       "      <td>N</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>0101010C0AAAMAM</td>\n",
       "      <td>Alum Hydrox_Oral Susp 475mg/5ml</td>\n",
       "      <td>0101010C0AAAMAM</td>\n",
       "      <td>Aluminium hydroxide 475mg/5ml oral suspension</td>\n",
       "      <td>N</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>0101010C0BBAAAA</td>\n",
       "      <td>Alu-Cap_Cap 475mg</td>\n",
       "      <td>0101010C0BBAAAA</td>\n",
       "      <td>Alu-Cap 475mg capsules</td>\n",
       "      <td>N</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>0101010E0AAAEAE</td>\n",
       "      <td>Hydrotalcite_Oral Susp 500mg/5ml S/F</td>\n",
       "      <td>0101010E0AAAEAE</td>\n",
       "      <td>Hydrotalcite 500mg/5ml oral suspension sugar free</td>\n",
       "      <td>N</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "  Current BNF Code                  MDR: BNF Description     New BNF Code  \\\n",
       "0  0101010C0AAAAAA  Alum Hydrox_Cap 475mg                 0101010C0AAAAAA   \n",
       "1  0101010C0AAACAC  Alum Hydrox_Oral Susp S/F             0101010C0AAACAC   \n",
       "2  0101010C0AAAMAM  Alum Hydrox_Oral Susp 475mg/5ml       0101010C0AAAMAM   \n",
       "3  0101010C0BBAAAA  Alu-Cap_Cap 475mg                     0101010C0BBAAAA   \n",
       "4  0101010E0AAAEAE  Hydrotalcite_Oral Susp 500mg/5ml S/F  0101010E0AAAEAE   \n",
       "\n",
       "                               dm+d: BNF Description BNF Code Changed (Y/N)  \n",
       "0  Aluminium hydroxide 475mg capsules                 N                      \n",
       "1  Aluminium hydroxide oral suspension sugar free     N                      \n",
       "2  Aluminium hydroxide 475mg/5ml oral suspension      N                      \n",
       "3  Alu-Cap 475mg capsules                             N                      \n",
       "4  Hydrotalcite 500mg/5ml oral suspension sugar free  N                      "
      ]
     },
     "execution_count": 5,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# Load the data from the spreadsheet\n",
    "bnf_mapping_raw = pd.read_excel('../data/MDR BNF to dm+d BNF Mapping.xlsx')\n",
    "bnf_mapping_raw.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "There are 1946 changed records\n"
     ]
    },
    {
     "data": {
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       "\n",
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       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>56</th>\n",
       "      <td>0101010N0AAAAAA</td>\n",
       "      <td>Antacid/Oxetacaine_Oral Susp S/F</td>\n",
       "      <td>0101010N0AAABAB</td>\n",
       "      <td>Antacid and Oxetacaine oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>81</th>\n",
       "      <td>0101012B0AAAUAU</td>\n",
       "      <td>Sod Bicarb_Liq Spec 420mg/5ml</td>\n",
       "      <td>0101012B0AAABAB</td>\n",
       "      <td>Sodium bicarbonate 420mg/5ml (1mol/ml) soln sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>97</th>\n",
       "      <td>0101012B0AABVBV</td>\n",
       "      <td>Sod Bicarb_Oral Soln 50mg/5ml (Old)</td>\n",
       "      <td>0101012B0AABXBX</td>\n",
       "      <td>Sodium bicarbonate 50mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>87</th>\n",
       "      <td>0101012B0AABWBW</td>\n",
       "      <td>Sod Bicarb_Oral Soln 420mg/5ml</td>\n",
       "      <td>0101012B0AAAUAU</td>\n",
       "      <td>Sodium bicarbonate 420mg/5ml (1mmol/ml) oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100</th>\n",
       "      <td>0101012B0BKAABY</td>\n",
       "      <td>Boots_Gripe Mix S/F</td>\n",
       "      <td>0101012B0AABYBY</td>\n",
       "      <td>Sodium bicarbonate 50mg/5ml oral solution sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "            old_code                             old_name         new_code  \\\n",
       "56   0101010N0AAAAAA  Antacid/Oxetacaine_Oral Susp S/F     0101010N0AAABAB   \n",
       "81   0101012B0AAAUAU  Sod Bicarb_Liq Spec 420mg/5ml        0101012B0AAABAB   \n",
       "97   0101012B0AABVBV  Sod Bicarb_Oral Soln 50mg/5ml (Old)  0101012B0AABXBX   \n",
       "87   0101012B0AABWBW  Sod Bicarb_Oral Soln 420mg/5ml       0101012B0AAAUAU   \n",
       "100  0101012B0BKAABY  Boots_Gripe Mix S/F                  0101012B0AABYBY   \n",
       "\n",
       "                                                   new_name changed  \n",
       "56   Antacid and Oxetacaine oral suspension                  Y       \n",
       "81   Sodium bicarbonate 420mg/5ml (1mol/ml) soln sugar free  Y       \n",
       "97   Sodium bicarbonate 50mg/5ml oral solution               Y       \n",
       "87   Sodium bicarbonate 420mg/5ml (1mmol/ml) oral liquid     Y       \n",
       "100  Sodium bicarbonate 50mg/5ml oral solution sugar free    Y       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# Massage the data a bit, changing column names...\n",
    "bnf_mapping = bnf_mapping_raw.rename(columns={\n",
    "    'Current BNF Code': 'old_code',\n",
    "    'MDR: BNF Description': 'old_name',\n",
    "    'dm+d: BNF Description': 'new_name',\n",
    "    'New BNF Code': 'new_code',\n",
    "    'BNF Code Changed (Y/N)': 'changed'\n",
    "})\n",
    "# ...dropping rows where the code hasn't changed...\n",
    "bnf_mapping = bnf_mapping[bnf_mapping['changed'] == 'Y']\n",
    "# ...dropping rows where the old_code is in chapter 19...\n",
    "bnf_mapping = bnf_mapping[~bnf_mapping['old_code'].str.startswith('19')]\n",
    "# ...dropping rows where the new_code is in chapter 19...\n",
    "bnf_mapping = bnf_mapping[~bnf_mapping['new_code'].str.startswith('19')]\n",
    "# ...and sorting by old_code and new_code\n",
    "bnf_mapping = bnf_mapping.sort_values(['old_code', 'new_code'])\n",
    "\n",
    "print(f\"There are {len(bnf_mapping)} changed records\")\n",
    "display(bnf_mapping.head())"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Distribution of numbers of new presentations that are mapped to\n",
    "\n",
    "_(Is there a better way to express this?)_"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "There are 1501 distinct old BNF codes:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1501"
      ]
     },
     "execution_count": 7,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping['old_code'].nunique()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "There are 1418 old BNF codes map to a single new BNF code, 37 old BNF codes map to 2 new BNF codes... and 1 maps to 112 new BNF codes:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
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       "        vertical-align: middle;\n",
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       "\n",
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       "\n",
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       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>num_old_codes</th>\n",
       "      <th>num_new_codes_mapped_to</th>\n",
       "    </tr>\n",
       "  </thead>\n",
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       "      <th>0</th>\n",
       "      <td>1418</td>\n",
       "      <td>1</td>\n",
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       "      <th>1</th>\n",
       "      <td>37</td>\n",
       "      <td>2</td>\n",
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       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>41</td>\n",
       "      <td>3</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>1</td>\n",
       "      <td>5</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>2</td>\n",
       "      <td>57</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>1</td>\n",
       "      <td>100</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>1</td>\n",
       "      <td>112</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "   num_old_codes  num_new_codes_mapped_to\n",
       "0  1418           1                      \n",
       "1  37             2                      \n",
       "2  41             3                      \n",
       "3  1              5                      \n",
       "4  2              57                     \n",
       "5  1              100                    \n",
       "6  1              112                    "
      ]
     },
     "execution_count": 8,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "old_code_counts = Counter(bnf_mapping['old_code'])\n",
    "old_code_count_distribution = sorted(Counter(old_code_counts.values()).items())\n",
    "rows = [\n",
    "    [num_old_codes, num_new_codes_mapped_to]\n",
    "    for num_new_codes_mapped_to, num_old_codes in old_code_count_distribution\n",
    "]\n",
    "pd.DataFrame(rows, columns=['num_old_codes', 'num_new_codes_mapped_to'])"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Old presentations mapping to 2 new codes"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
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       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>269</th>\n",
       "      <td>0102000L0AAAJAJ</td>\n",
       "      <td>Glycopyrronium Brom_Liq Spec 500mcg/5ml</td>\n",
       "      <td>0102000L0AABHBH</td>\n",
       "      <td>Glycopyrronium bromide 500micrograms/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>271</th>\n",
       "      <td>0102000L0AAAJAJ</td>\n",
       "      <td>Glycopyrronium Brom_Liq Spec 500mcg/5ml</td>\n",
       "      <td>0102000L0AABIBI</td>\n",
       "      <td>Glycopyrronium bromide 500micrograms/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1504</th>\n",
       "      <td>0204000H0AAAUAU</td>\n",
       "      <td>Bisoprolol Fumar_OralSoln1.25mg/5ml(Old)</td>\n",
       "      <td>0204000H0AABIBI</td>\n",
       "      <td>Bisoprolol 1.25mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1506</th>\n",
       "      <td>0204000H0AAAUAU</td>\n",
       "      <td>Bisoprolol Fumar_OralSoln1.25mg/5ml(Old)</td>\n",
       "      <td>0204000H0AABJBJ</td>\n",
       "      <td>Bisoprolol 1.25mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1913</th>\n",
       "      <td>0205051L0AAAFAF</td>\n",
       "      <td>Lisinopril_Liq Spec 20mg/5ml</td>\n",
       "      <td>0205051L0AAAYAY</td>\n",
       "      <td>Lisinopril 20mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1915</th>\n",
       "      <td>0205051L0AAAFAF</td>\n",
       "      <td>Lisinopril_Liq Spec 20mg/5ml</td>\n",
       "      <td>0205051L0AAAZAZ</td>\n",
       "      <td>Lisinopril 20mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2184</th>\n",
       "      <td>0206010F0AAAAAA</td>\n",
       "      <td>Glyceryl Trinit_Subling Spy 400mcg(200D)</td>\n",
       "      <td>0206010F0AACGCG</td>\n",
       "      <td>Glyceryl trinitrate 400micrograms/dose aerosol SL spy</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2188</th>\n",
       "      <td>0206010F0AAAAAA</td>\n",
       "      <td>Glyceryl Trinit_Subling Spy 400mcg(200D)</td>\n",
       "      <td>0206010F0AACICI</td>\n",
       "      <td>Glyceryl trinitrate 400micrograms/dose pump sublingual spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4108</th>\n",
       "      <td>0401010ADAABUBU</td>\n",
       "      <td>Melatonin_Liq Spec 10mg/5ml</td>\n",
       "      <td>0401010ADAACDCD</td>\n",
       "      <td>Melatonin 10mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4110</th>\n",
       "      <td>0401010ADAABUBU</td>\n",
       "      <td>Melatonin_Liq Spec 10mg/5ml</td>\n",
       "      <td>0401010ADAACECE</td>\n",
       "      <td>Melatonin 10mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5561</th>\n",
       "      <td>0407010H0AAAAAA</td>\n",
       "      <td>Paracet_Cap 500mg</td>\n",
       "      <td>0407010H0B3AKAA</td>\n",
       "      <td>Boots Paracetamol 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5585</th>\n",
       "      <td>0407010H0AAAAAA</td>\n",
       "      <td>Paracet_Cap 500mg</td>\n",
       "      <td>0407010H0BUAAAA</td>\n",
       "      <td>Numark Paracetamol 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7631</th>\n",
       "      <td>0410030E0AAARAR</td>\n",
       "      <td>Naltrexone HCl_Oral Soln 5mg/5ml (Old)</td>\n",
       "      <td>0410030E0AAATAT</td>\n",
       "      <td>Naltrexone 5mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7635</th>\n",
       "      <td>0410030E0AAARAR</td>\n",
       "      <td>Naltrexone HCl_Oral Soln 5mg/5ml (Old)</td>\n",
       "      <td>0410030E0AAAVAV</td>\n",
       "      <td>Naltrexone 5mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10719</th>\n",
       "      <td>070405000BBADA0</td>\n",
       "      <td>Invicorp-2_Inj Soln 1ml Amp</td>\n",
       "      <td>0704050ADAAAAAA</td>\n",
       "      <td>Phentolamine 2mg/0.35ml / Aviptadil 25microg/0.35ml inj amp</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10722</th>\n",
       "      <td>070405000BBADA0</td>\n",
       "      <td>Invicorp-2_Inj Soln 1ml Amp</td>\n",
       "      <td>0704050ADBBABAA</td>\n",
       "      <td>Invicorp 2 solution for injection</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12160</th>\n",
       "      <td>090401000BBIEA0</td>\n",
       "      <td>Maxijul Super Solb_Pdr Sach 132g</td>\n",
       "      <td>090401000AAANAN</td>\n",
       "      <td>Generic Maxijul Super Soluble powder</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12193</th>\n",
       "      <td>090401000BBIEA0</td>\n",
       "      <td>Maxijul Super Solb_Pdr Sach 132g</td>\n",
       "      <td>090401000BBCJAN</td>\n",
       "      <td>Maxijul Super Soluble powder</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12385</th>\n",
       "      <td>090401000BBMRA0</td>\n",
       "      <td>PKU Lophlex LQ_20 Liq (Berry)</td>\n",
       "      <td>090401000BBRPA0</td>\n",
       "      <td>PKU Lophlex LQ 20 liquid (6 flavours)</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12426</th>\n",
       "      <td>090401000BBMRA0</td>\n",
       "      <td>PKU Lophlex LQ_20 Liq (Berry)</td>\n",
       "      <td>090401000BBTDA0</td>\n",
       "      <td>PKU Lophlex LQ 20 liquid citrus</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12380</th>\n",
       "      <td>090401000BBNNA0</td>\n",
       "      <td>PKU Lophlex LQ_10 Liq (4 Flav)</td>\n",
       "      <td>090401000BBRLA0</td>\n",
       "      <td>PKU Lophlex LQ 10 liquid (5 flavours)</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12425</th>\n",
       "      <td>090401000BBNNA0</td>\n",
       "      <td>PKU Lophlex LQ_10 Liq (4 Flav)</td>\n",
       "      <td>090401000BBTBA0</td>\n",
       "      <td>PKU Lophlex LQ 10 liquid citrus</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12670</th>\n",
       "      <td>0904010U0AAAAAA</td>\n",
       "      <td>G/F /W/F_Bread</td>\n",
       "      <td>0904010A0AABFBF</td>\n",
       "      <td>Gluten free biscuits</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12922</th>\n",
       "      <td>0904010U0AAAAAA</td>\n",
       "      <td>G/F /W/F_Bread</td>\n",
       "      <td>0904010H0AAAAAA</td>\n",
       "      <td>Gluten free bread</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13273</th>\n",
       "      <td>090402000BBKLA0</td>\n",
       "      <td>Peptamen_Dripac-Flex Liq (Unflav)</td>\n",
       "      <td>090402000AAASAS</td>\n",
       "      <td>Generic Peptamen liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13339</th>\n",
       "      <td>090402000BBKLA0</td>\n",
       "      <td>Peptamen_Dripac-Flex Liq (Unflav)</td>\n",
       "      <td>090402000BBIGA0</td>\n",
       "      <td>Peptamen liquid unflavoured</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14106</th>\n",
       "      <td>090602400BBCGA0</td>\n",
       "      <td>Solgar_Vit B6 Cap 100mg (OLD)</td>\n",
       "      <td>0906024N0AABEBE</td>\n",
       "      <td>Pyridoxine 100mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14138</th>\n",
       "      <td>090602400BBCGA0</td>\n",
       "      <td>Solgar_Vit B6 Cap 100mg (OLD)</td>\n",
       "      <td>0906024N0CKAABE</td>\n",
       "      <td>Solgar Vitamin B6 100mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14122</th>\n",
       "      <td>0906024N0AABLBL</td>\n",
       "      <td>Pyridox HCl_Liq Spec 100mg/5ml</td>\n",
       "      <td>0906024N0AACXCX</td>\n",
       "      <td>Pyridoxine 100mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14124</th>\n",
       "      <td>0906024N0AABLBL</td>\n",
       "      <td>Pyridox HCl_Liq Spec 100mg/5ml</td>\n",
       "      <td>0906024N0AACYCY</td>\n",
       "      <td>Pyridoxine 100mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14860</th>\n",
       "      <td>0906027G0AAABAB</td>\n",
       "      <td>Vit B Co Strong_Tab</td>\n",
       "      <td>090607000AABBBB</td>\n",
       "      <td>Multivitamin tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15497</th>\n",
       "      <td>0906027G0AAABAB</td>\n",
       "      <td>Vit B Co Strong_Tab</td>\n",
       "      <td>091200000AAFTFT</td>\n",
       "      <td>Multinutrient tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14394</th>\n",
       "      <td>0906040G0AAAUAU</td>\n",
       "      <td>Colecal_Oral Susp 15,000u/5ml</td>\n",
       "      <td>0906040G0AADEDE</td>\n",
       "      <td>Colecalciferol 5,000units/ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14409</th>\n",
       "      <td>0906040G0AAAUAU</td>\n",
       "      <td>Colecal_Oral Susp 15,000u/5ml</td>\n",
       "      <td>0906040G0AADSDS</td>\n",
       "      <td>Colecalciferol 15,000units/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16272</th>\n",
       "      <td>1001030U0AABTBT</td>\n",
       "      <td>Methotrexate_Oral Soln 10mg/5ml</td>\n",
       "      <td>1001030U0AAAHAH</td>\n",
       "      <td>Methotrexate 10mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16309</th>\n",
       "      <td>1001030U0AABTBT</td>\n",
       "      <td>Methotrexate_Oral Soln 10mg/5ml</td>\n",
       "      <td>1001030U0AACFCF</td>\n",
       "      <td>Methotrexate 2mg/ml oral solution sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16485</th>\n",
       "      <td>1002010Q0AAAIAI</td>\n",
       "      <td>Pyridostig Brom_Liq Spec 60mg/5ml</td>\n",
       "      <td>1002010Q0AABFBF</td>\n",
       "      <td>Pyridostigmine bromide 60mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16491</th>\n",
       "      <td>1002010Q0AAAIAI</td>\n",
       "      <td>Pyridostig Brom_Liq Spec 60mg/5ml</td>\n",
       "      <td>1002010Q0AABIBI</td>\n",
       "      <td>Pyridostigmine bromide 60mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17083</th>\n",
       "      <td>110801000BLAQA0</td>\n",
       "      <td>Blephaclean_Eye Lid Wipe (Drug)</td>\n",
       "      <td>110801000AAABAB</td>\n",
       "      <td>Generic Lid-Care wipes</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>29069</th>\n",
       "      <td>110801000BLAQA0</td>\n",
       "      <td>Blephaclean_Eye Lid Wipe (Drug)</td>\n",
       "      <td>21300000850</td>\n",
       "      <td>Blephaclean wipes</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19493</th>\n",
       "      <td>1313010S0BBAAA0</td>\n",
       "      <td>Zipzoc_Zn Ox Impregnated Medic Stkn(Old)</td>\n",
       "      <td>1313010S0AAAAAA</td>\n",
       "      <td>Zinc oxide impregnated medicated stockings</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19494</th>\n",
       "      <td>1313010S0BBAAA0</td>\n",
       "      <td>Zipzoc_Zn Ox Impregnated Medic Stkn(Old)</td>\n",
       "      <td>1313010S0BBABAA</td>\n",
       "      <td>Zipzoc stockings</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21503</th>\n",
       "      <td>20030300026</td>\n",
       "      <td>L-Mesitran Oint 50g Wound Dress H/Base Top Applic</td>\n",
       "      <td>20030300025</td>\n",
       "      <td>Mesitran ointment dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21505</th>\n",
       "      <td>20030300026</td>\n",
       "      <td>L-Mesitran Oint 50g Wound Dress H/Base Top Applic</td>\n",
       "      <td>20030300028</td>\n",
       "      <td>L-Mesitran ointment dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24709</th>\n",
       "      <td>20200000175</td>\n",
       "      <td>DermaSilk Brief Adult (Fle) XSml-Sml Silk Garment</td>\n",
       "      <td>20200000333</td>\n",
       "      <td>DermaSilk briefs female adult medium-large</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24711</th>\n",
       "      <td>20200000175</td>\n",
       "      <td>DermaSilk Brief Adult (Fle) XSml-Sml Silk Garment</td>\n",
       "      <td>20200000334</td>\n",
       "      <td>DermaSilk briefs female adult extra large-XX large</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>25599</th>\n",
       "      <td>21020001000</td>\n",
       "      <td>Hollister InstantCath Protect Nelaton 8 (25-Pack) Cath</td>\n",
       "      <td>21020001002</td>\n",
       "      <td>InstantCath Protect catheter 14Ch</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>25601</th>\n",
       "      <td>21020001000</td>\n",
       "      <td>Hollister InstantCath Protect Nelaton 8 (25-Pack) Cath</td>\n",
       "      <td>21020001003</td>\n",
       "      <td>InstantCath Protect catheter 18Ch</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17845</th>\n",
       "      <td>21220000118</td>\n",
       "      <td>Flexitol 10% Urea Crm 500g</td>\n",
       "      <td>1302010U0AAAFAF</td>\n",
       "      <td>Urea 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26396</th>\n",
       "      <td>21220000118</td>\n",
       "      <td>Flexitol 10% Urea Crm 500g</td>\n",
       "      <td>21220000117</td>\n",
       "      <td>Flexitol 10% Urea cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17727</th>\n",
       "      <td>21220000234</td>\n",
       "      <td>Cetraben Crm 150g</td>\n",
       "      <td>130201000AACFCF</td>\n",
       "      <td>White soft paraffin 13.2% /Liquid paraffin light 10.5% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26454</th>\n",
       "      <td>21220000234</td>\n",
       "      <td>Cetraben Crm 150g</td>\n",
       "      <td>21220000233</td>\n",
       "      <td>Cetraben cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17728</th>\n",
       "      <td>21220000235</td>\n",
       "      <td>Cetraben Crm 500g</td>\n",
       "      <td>130201000AACFCF</td>\n",
       "      <td>White soft paraffin 13.2% /Liquid paraffin light 10.5% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26455</th>\n",
       "      <td>21220000235</td>\n",
       "      <td>Cetraben Crm 500g</td>\n",
       "      <td>21220000233</td>\n",
       "      <td>Cetraben cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17729</th>\n",
       "      <td>21220000236</td>\n",
       "      <td>Cetraben Crm 1050g</td>\n",
       "      <td>130201000AACFCF</td>\n",
       "      <td>White soft paraffin 13.2% /Liquid paraffin light 10.5% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26456</th>\n",
       "      <td>21220000236</td>\n",
       "      <td>Cetraben Crm 1050g</td>\n",
       "      <td>21220000233</td>\n",
       "      <td>Cetraben cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17718</th>\n",
       "      <td>21220000252</td>\n",
       "      <td>Isomol Gel 500g</td>\n",
       "      <td>130201000AACACA</td>\n",
       "      <td>Isopropyl myristate 15% / Liquid paraffin 15% gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26476</th>\n",
       "      <td>21220000252</td>\n",
       "      <td>Isomol Gel 500g</td>\n",
       "      <td>21220000251</td>\n",
       "      <td>isomol gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17720</th>\n",
       "      <td>21220000261</td>\n",
       "      <td>MyriBase Gel 500g</td>\n",
       "      <td>130201000AACACA</td>\n",
       "      <td>Isopropyl myristate 15% / Liquid paraffin 15% gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26486</th>\n",
       "      <td>21220000261</td>\n",
       "      <td>MyriBase Gel 500g</td>\n",
       "      <td>21220000260</td>\n",
       "      <td>MyriBase gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17721</th>\n",
       "      <td>21220000263</td>\n",
       "      <td>AproDerm Gel 500g</td>\n",
       "      <td>130201000AACACA</td>\n",
       "      <td>Isopropyl myristate 15% / Liquid paraffin 15% gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26489</th>\n",
       "      <td>21220000263</td>\n",
       "      <td>AproDerm Gel 500g</td>\n",
       "      <td>21220000262</td>\n",
       "      <td>AproDerm gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17891</th>\n",
       "      <td>21220000268</td>\n",
       "      <td>AquaDerm Aq Crm</td>\n",
       "      <td>130201100AAAMAM</td>\n",
       "      <td>Aqueous cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26491</th>\n",
       "      <td>21220000268</td>\n",
       "      <td>AquaDerm Aq Crm</td>\n",
       "      <td>21220000267</td>\n",
       "      <td>AquaDerm Aqueous cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17705</th>\n",
       "      <td>21220000272</td>\n",
       "      <td>AquaDerm Liq Par 50%/WSP Oint 500g</td>\n",
       "      <td>130201000AAA6A6</td>\n",
       "      <td>White soft paraffin 50% / Liquid paraffin 50% ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26495</th>\n",
       "      <td>21220000272</td>\n",
       "      <td>AquaDerm Liq Par 50%/WSP Oint 500g</td>\n",
       "      <td>21220000271</td>\n",
       "      <td>AquaDerm Liquid Paraffin 50% in White Soft Paraffin ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17847</th>\n",
       "      <td>21220000279</td>\n",
       "      <td>Aquadrate Crm 10% 100g (App)</td>\n",
       "      <td>1302010U0AAAFAF</td>\n",
       "      <td>Urea 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26504</th>\n",
       "      <td>21220000279</td>\n",
       "      <td>Aquadrate Crm 10% 100g (App)</td>\n",
       "      <td>21220000278</td>\n",
       "      <td>Aquadrate 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17849</th>\n",
       "      <td>21220000281</td>\n",
       "      <td>Hydromol Intensive Crm 10% 100g (App)</td>\n",
       "      <td>1302010U0AAAFAF</td>\n",
       "      <td>Urea 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26507</th>\n",
       "      <td>21220000281</td>\n",
       "      <td>Hydromol Intensive Crm 10% 100g (App)</td>\n",
       "      <td>21220000280</td>\n",
       "      <td>Hydromol Intensive 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31640</th>\n",
       "      <td>23300263031</td>\n",
       "      <td>AMI_Suportx Ostomy/Hernia Supp/Belt 15cm+Hole Sml (75-90cm)</td>\n",
       "      <td>23300263864</td>\n",
       "      <td>Suportx ostomy belt with hole cutting, small 15cm black</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31645</th>\n",
       "      <td>23300263031</td>\n",
       "      <td>AMI_Suportx Ostomy/Hernia Supp/Belt 15cm+Hole Sml (75-90cm)</td>\n",
       "      <td>23300263870</td>\n",
       "      <td>Suportx ostomy belt with hole cutting, small 15cm skin</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31644</th>\n",
       "      <td>23300263036</td>\n",
       "      <td>AMI_Suportx Ostomy/Hernia Supp Belt 15cm + Hole (Bespoke)</td>\n",
       "      <td>23300263869</td>\n",
       "      <td>Suportx ostomy belt with hole cutting, made to measure 15cm black</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31651</th>\n",
       "      <td>23300263036</td>\n",
       "      <td>AMI_Suportx Ostomy/Hernia Supp Belt 15cm + Hole (Bespoke)</td>\n",
       "      <td>23300263875</td>\n",
       "      <td>Suportx ostomy belt with hole cutting, made to measure 15cm skin</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "              old_code  \\\n",
       "269    0102000L0AAAJAJ   \n",
       "271    0102000L0AAAJAJ   \n",
       "1504   0204000H0AAAUAU   \n",
       "1506   0204000H0AAAUAU   \n",
       "1913   0205051L0AAAFAF   \n",
       "1915   0205051L0AAAFAF   \n",
       "2184   0206010F0AAAAAA   \n",
       "2188   0206010F0AAAAAA   \n",
       "4108   0401010ADAABUBU   \n",
       "4110   0401010ADAABUBU   \n",
       "5561   0407010H0AAAAAA   \n",
       "5585   0407010H0AAAAAA   \n",
       "7631   0410030E0AAARAR   \n",
       "7635   0410030E0AAARAR   \n",
       "10719  070405000BBADA0   \n",
       "10722  070405000BBADA0   \n",
       "12160  090401000BBIEA0   \n",
       "12193  090401000BBIEA0   \n",
       "12385  090401000BBMRA0   \n",
       "12426  090401000BBMRA0   \n",
       "12380  090401000BBNNA0   \n",
       "12425  090401000BBNNA0   \n",
       "12670  0904010U0AAAAAA   \n",
       "12922  0904010U0AAAAAA   \n",
       "13273  090402000BBKLA0   \n",
       "13339  090402000BBKLA0   \n",
       "14106  090602400BBCGA0   \n",
       "14138  090602400BBCGA0   \n",
       "14122  0906024N0AABLBL   \n",
       "14124  0906024N0AABLBL   \n",
       "14860  0906027G0AAABAB   \n",
       "15497  0906027G0AAABAB   \n",
       "14394  0906040G0AAAUAU   \n",
       "14409  0906040G0AAAUAU   \n",
       "16272  1001030U0AABTBT   \n",
       "16309  1001030U0AABTBT   \n",
       "16485  1002010Q0AAAIAI   \n",
       "16491  1002010Q0AAAIAI   \n",
       "17083  110801000BLAQA0   \n",
       "29069  110801000BLAQA0   \n",
       "19493  1313010S0BBAAA0   \n",
       "19494  1313010S0BBAAA0   \n",
       "21503  20030300026       \n",
       "21505  20030300026       \n",
       "24709  20200000175       \n",
       "24711  20200000175       \n",
       "25599  21020001000       \n",
       "25601  21020001000       \n",
       "17845  21220000118       \n",
       "26396  21220000118       \n",
       "17727  21220000234       \n",
       "26454  21220000234       \n",
       "17728  21220000235       \n",
       "26455  21220000235       \n",
       "17729  21220000236       \n",
       "26456  21220000236       \n",
       "17718  21220000252       \n",
       "26476  21220000252       \n",
       "17720  21220000261       \n",
       "26486  21220000261       \n",
       "17721  21220000263       \n",
       "26489  21220000263       \n",
       "17891  21220000268       \n",
       "26491  21220000268       \n",
       "17705  21220000272       \n",
       "26495  21220000272       \n",
       "17847  21220000279       \n",
       "26504  21220000279       \n",
       "17849  21220000281       \n",
       "26507  21220000281       \n",
       "31640  23300263031       \n",
       "31645  23300263031       \n",
       "31644  23300263036       \n",
       "31651  23300263036       \n",
       "\n",
       "                                                          old_name  \\\n",
       "269    Glycopyrronium Brom_Liq Spec 500mcg/5ml                       \n",
       "271    Glycopyrronium Brom_Liq Spec 500mcg/5ml                       \n",
       "1504   Bisoprolol Fumar_OralSoln1.25mg/5ml(Old)                      \n",
       "1506   Bisoprolol Fumar_OralSoln1.25mg/5ml(Old)                      \n",
       "1913   Lisinopril_Liq Spec 20mg/5ml                                  \n",
       "1915   Lisinopril_Liq Spec 20mg/5ml                                  \n",
       "2184   Glyceryl Trinit_Subling Spy 400mcg(200D)                      \n",
       "2188   Glyceryl Trinit_Subling Spy 400mcg(200D)                      \n",
       "4108   Melatonin_Liq Spec 10mg/5ml                                   \n",
       "4110   Melatonin_Liq Spec 10mg/5ml                                   \n",
       "5561   Paracet_Cap 500mg                                             \n",
       "5585   Paracet_Cap 500mg                                             \n",
       "7631   Naltrexone HCl_Oral Soln 5mg/5ml (Old)                        \n",
       "7635   Naltrexone HCl_Oral Soln 5mg/5ml (Old)                        \n",
       "10719  Invicorp-2_Inj Soln 1ml Amp                                   \n",
       "10722  Invicorp-2_Inj Soln 1ml Amp                                   \n",
       "12160  Maxijul Super Solb_Pdr Sach 132g                              \n",
       "12193  Maxijul Super Solb_Pdr Sach 132g                              \n",
       "12385  PKU Lophlex LQ_20 Liq (Berry)                                 \n",
       "12426  PKU Lophlex LQ_20 Liq (Berry)                                 \n",
       "12380  PKU Lophlex LQ_10 Liq (4 Flav)                                \n",
       "12425  PKU Lophlex LQ_10 Liq (4 Flav)                                \n",
       "12670  G/F /W/F_Bread                                                \n",
       "12922  G/F /W/F_Bread                                                \n",
       "13273  Peptamen_Dripac-Flex Liq (Unflav)                             \n",
       "13339  Peptamen_Dripac-Flex Liq (Unflav)                             \n",
       "14106  Solgar_Vit B6 Cap 100mg (OLD)                                 \n",
       "14138  Solgar_Vit B6 Cap 100mg (OLD)                                 \n",
       "14122  Pyridox HCl_Liq Spec 100mg/5ml                                \n",
       "14124  Pyridox HCl_Liq Spec 100mg/5ml                                \n",
       "14860  Vit B Co Strong_Tab                                           \n",
       "15497  Vit B Co Strong_Tab                                           \n",
       "14394  Colecal_Oral Susp 15,000u/5ml                                 \n",
       "14409  Colecal_Oral Susp 15,000u/5ml                                 \n",
       "16272  Methotrexate_Oral Soln 10mg/5ml                               \n",
       "16309  Methotrexate_Oral Soln 10mg/5ml                               \n",
       "16485  Pyridostig Brom_Liq Spec 60mg/5ml                             \n",
       "16491  Pyridostig Brom_Liq Spec 60mg/5ml                             \n",
       "17083  Blephaclean_Eye Lid Wipe (Drug)                               \n",
       "29069  Blephaclean_Eye Lid Wipe (Drug)                               \n",
       "19493  Zipzoc_Zn Ox Impregnated Medic Stkn(Old)                      \n",
       "19494  Zipzoc_Zn Ox Impregnated Medic Stkn(Old)                      \n",
       "21503  L-Mesitran Oint 50g Wound Dress H/Base Top Applic             \n",
       "21505  L-Mesitran Oint 50g Wound Dress H/Base Top Applic             \n",
       "24709  DermaSilk Brief Adult (Fle) XSml-Sml Silk Garment             \n",
       "24711  DermaSilk Brief Adult (Fle) XSml-Sml Silk Garment             \n",
       "25599  Hollister InstantCath Protect Nelaton 8 (25-Pack) Cath        \n",
       "25601  Hollister InstantCath Protect Nelaton 8 (25-Pack) Cath        \n",
       "17845  Flexitol 10% Urea Crm 500g                                    \n",
       "26396  Flexitol 10% Urea Crm 500g                                    \n",
       "17727  Cetraben Crm 150g                                             \n",
       "26454  Cetraben Crm 150g                                             \n",
       "17728  Cetraben Crm 500g                                             \n",
       "26455  Cetraben Crm 500g                                             \n",
       "17729  Cetraben Crm 1050g                                            \n",
       "26456  Cetraben Crm 1050g                                            \n",
       "17718  Isomol Gel 500g                                               \n",
       "26476  Isomol Gel 500g                                               \n",
       "17720  MyriBase Gel 500g                                             \n",
       "26486  MyriBase Gel 500g                                             \n",
       "17721  AproDerm Gel 500g                                             \n",
       "26489  AproDerm Gel 500g                                             \n",
       "17891  AquaDerm Aq Crm                                               \n",
       "26491  AquaDerm Aq Crm                                               \n",
       "17705  AquaDerm Liq Par 50%/WSP Oint 500g                            \n",
       "26495  AquaDerm Liq Par 50%/WSP Oint 500g                            \n",
       "17847  Aquadrate Crm 10% 100g (App)                                  \n",
       "26504  Aquadrate Crm 10% 100g (App)                                  \n",
       "17849  Hydromol Intensive Crm 10% 100g (App)                         \n",
       "26507  Hydromol Intensive Crm 10% 100g (App)                         \n",
       "31640  AMI_Suportx Ostomy/Hernia Supp/Belt 15cm+Hole Sml (75-90cm)   \n",
       "31645  AMI_Suportx Ostomy/Hernia Supp/Belt 15cm+Hole Sml (75-90cm)   \n",
       "31644  AMI_Suportx Ostomy/Hernia Supp Belt 15cm + Hole (Bespoke)     \n",
       "31651  AMI_Suportx Ostomy/Hernia Supp Belt 15cm + Hole (Bespoke)     \n",
       "\n",
       "              new_code  \\\n",
       "269    0102000L0AABHBH   \n",
       "271    0102000L0AABIBI   \n",
       "1504   0204000H0AABIBI   \n",
       "1506   0204000H0AABJBJ   \n",
       "1913   0205051L0AAAYAY   \n",
       "1915   0205051L0AAAZAZ   \n",
       "2184   0206010F0AACGCG   \n",
       "2188   0206010F0AACICI   \n",
       "4108   0401010ADAACDCD   \n",
       "4110   0401010ADAACECE   \n",
       "5561   0407010H0B3AKAA   \n",
       "5585   0407010H0BUAAAA   \n",
       "7631   0410030E0AAATAT   \n",
       "7635   0410030E0AAAVAV   \n",
       "10719  0704050ADAAAAAA   \n",
       "10722  0704050ADBBABAA   \n",
       "12160  090401000AAANAN   \n",
       "12193  090401000BBCJAN   \n",
       "12385  090401000BBRPA0   \n",
       "12426  090401000BBTDA0   \n",
       "12380  090401000BBRLA0   \n",
       "12425  090401000BBTBA0   \n",
       "12670  0904010A0AABFBF   \n",
       "12922  0904010H0AAAAAA   \n",
       "13273  090402000AAASAS   \n",
       "13339  090402000BBIGA0   \n",
       "14106  0906024N0AABEBE   \n",
       "14138  0906024N0CKAABE   \n",
       "14122  0906024N0AACXCX   \n",
       "14124  0906024N0AACYCY   \n",
       "14860  090607000AABBBB   \n",
       "15497  091200000AAFTFT   \n",
       "14394  0906040G0AADEDE   \n",
       "14409  0906040G0AADSDS   \n",
       "16272  1001030U0AAAHAH   \n",
       "16309  1001030U0AACFCF   \n",
       "16485  1002010Q0AABFBF   \n",
       "16491  1002010Q0AABIBI   \n",
       "17083  110801000AAABAB   \n",
       "29069  21300000850       \n",
       "19493  1313010S0AAAAAA   \n",
       "19494  1313010S0BBABAA   \n",
       "21503  20030300025       \n",
       "21505  20030300028       \n",
       "24709  20200000333       \n",
       "24711  20200000334       \n",
       "25599  21020001002       \n",
       "25601  21020001003       \n",
       "17845  1302010U0AAAFAF   \n",
       "26396  21220000117       \n",
       "17727  130201000AACFCF   \n",
       "26454  21220000233       \n",
       "17728  130201000AACFCF   \n",
       "26455  21220000233       \n",
       "17729  130201000AACFCF   \n",
       "26456  21220000233       \n",
       "17718  130201000AACACA   \n",
       "26476  21220000251       \n",
       "17720  130201000AACACA   \n",
       "26486  21220000260       \n",
       "17721  130201000AACACA   \n",
       "26489  21220000262       \n",
       "17891  130201100AAAMAM   \n",
       "26491  21220000267       \n",
       "17705  130201000AAA6A6   \n",
       "26495  21220000271       \n",
       "17847  1302010U0AAAFAF   \n",
       "26504  21220000278       \n",
       "17849  1302010U0AAAFAF   \n",
       "26507  21220000280       \n",
       "31640  23300263864       \n",
       "31645  23300263870       \n",
       "31644  23300263869       \n",
       "31651  23300263875       \n",
       "\n",
       "                                                                new_name  \\\n",
       "269    Glycopyrronium bromide 500micrograms/5ml oral solution              \n",
       "271    Glycopyrronium bromide 500micrograms/5ml oral suspension            \n",
       "1504   Bisoprolol 1.25mg/5ml oral suspension                               \n",
       "1506   Bisoprolol 1.25mg/5ml oral solution                                 \n",
       "1913   Lisinopril 20mg/5ml oral solution                                   \n",
       "1915   Lisinopril 20mg/5ml oral suspension                                 \n",
       "2184   Glyceryl trinitrate 400micrograms/dose aerosol SL spy               \n",
       "2188   Glyceryl trinitrate 400micrograms/dose pump sublingual spray        \n",
       "4108   Melatonin 10mg/5ml oral solution                                    \n",
       "4110   Melatonin 10mg/5ml oral suspension                                  \n",
       "5561   Boots Paracetamol 500mg capsules                                    \n",
       "5585   Numark Paracetamol 500mg capsules                                   \n",
       "7631   Naltrexone 5mg/5ml oral suspension                                  \n",
       "7635   Naltrexone 5mg/5ml oral solution                                    \n",
       "10719  Phentolamine 2mg/0.35ml / Aviptadil 25microg/0.35ml inj amp         \n",
       "10722  Invicorp 2 solution for injection                                   \n",
       "12160  Generic Maxijul Super Soluble powder                                \n",
       "12193  Maxijul Super Soluble powder                                        \n",
       "12385  PKU Lophlex LQ 20 liquid (6 flavours)                               \n",
       "12426  PKU Lophlex LQ 20 liquid citrus                                     \n",
       "12380  PKU Lophlex LQ 10 liquid (5 flavours)                               \n",
       "12425  PKU Lophlex LQ 10 liquid citrus                                     \n",
       "12670  Gluten free biscuits                                                \n",
       "12922  Gluten free bread                                                   \n",
       "13273  Generic Peptamen liquid                                             \n",
       "13339  Peptamen liquid unflavoured                                         \n",
       "14106  Pyridoxine 100mg capsules                                           \n",
       "14138  Solgar Vitamin B6 100mg capsules                                    \n",
       "14122  Pyridoxine 100mg/5ml oral solution                                  \n",
       "14124  Pyridoxine 100mg/5ml oral suspension                                \n",
       "14860  Multivitamin tablets                                                \n",
       "15497  Multinutrient tablets                                               \n",
       "14394  Colecalciferol 5,000units/ml oral solution                          \n",
       "14409  Colecalciferol 15,000units/5ml oral solution                        \n",
       "16272  Methotrexate 10mg/5ml oral liquid                                   \n",
       "16309  Methotrexate 2mg/ml oral solution sugar free                        \n",
       "16485  Pyridostigmine bromide 60mg/5ml oral solution                       \n",
       "16491  Pyridostigmine bromide 60mg/5ml oral suspension                     \n",
       "17083  Generic Lid-Care wipes                                              \n",
       "29069  Blephaclean wipes                                                   \n",
       "19493  Zinc oxide impregnated medicated stockings                          \n",
       "19494  Zipzoc stockings                                                    \n",
       "21503  Mesitran ointment dressing                                          \n",
       "21505  L-Mesitran ointment dressing                                        \n",
       "24709  DermaSilk briefs female adult medium-large                          \n",
       "24711  DermaSilk briefs female adult extra large-XX large                  \n",
       "25599  InstantCath Protect catheter 14Ch                                   \n",
       "25601  InstantCath Protect catheter 18Ch                                   \n",
       "17845  Urea 10% cream                                                      \n",
       "26396  Flexitol 10% Urea cream                                             \n",
       "17727  White soft paraffin 13.2% /Liquid paraffin light 10.5% cream        \n",
       "26454  Cetraben cream                                                      \n",
       "17728  White soft paraffin 13.2% /Liquid paraffin light 10.5% cream        \n",
       "26455  Cetraben cream                                                      \n",
       "17729  White soft paraffin 13.2% /Liquid paraffin light 10.5% cream        \n",
       "26456  Cetraben cream                                                      \n",
       "17718  Isopropyl myristate 15% / Liquid paraffin 15% gel                   \n",
       "26476  isomol gel                                                          \n",
       "17720  Isopropyl myristate 15% / Liquid paraffin 15% gel                   \n",
       "26486  MyriBase gel                                                        \n",
       "17721  Isopropyl myristate 15% / Liquid paraffin 15% gel                   \n",
       "26489  AproDerm gel                                                        \n",
       "17891  Aqueous cream                                                       \n",
       "26491  AquaDerm Aqueous cream                                              \n",
       "17705  White soft paraffin 50% / Liquid paraffin 50% ointment              \n",
       "26495  AquaDerm Liquid Paraffin 50% in White Soft Paraffin ointment        \n",
       "17847  Urea 10% cream                                                      \n",
       "26504  Aquadrate 10% cream                                                 \n",
       "17849  Urea 10% cream                                                      \n",
       "26507  Hydromol Intensive 10% cream                                        \n",
       "31640  Suportx ostomy belt with hole cutting, small 15cm black             \n",
       "31645  Suportx ostomy belt with hole cutting, small 15cm skin              \n",
       "31644  Suportx ostomy belt with hole cutting, made to measure 15cm black   \n",
       "31651  Suportx ostomy belt with hole cutting, made to measure 15cm skin    \n",
       "\n",
       "      changed  \n",
       "269    Y       \n",
       "271    Y       \n",
       "1504   Y       \n",
       "1506   Y       \n",
       "1913   Y       \n",
       "1915   Y       \n",
       "2184   Y       \n",
       "2188   Y       \n",
       "4108   Y       \n",
       "4110   Y       \n",
       "5561   Y       \n",
       "5585   Y       \n",
       "7631   Y       \n",
       "7635   Y       \n",
       "10719  Y       \n",
       "10722  Y       \n",
       "12160  Y       \n",
       "12193  Y       \n",
       "12385  Y       \n",
       "12426  Y       \n",
       "12380  Y       \n",
       "12425  Y       \n",
       "12670  Y       \n",
       "12922  Y       \n",
       "13273  Y       \n",
       "13339  Y       \n",
       "14106  Y       \n",
       "14138  Y       \n",
       "14122  Y       \n",
       "14124  Y       \n",
       "14860  Y       \n",
       "15497  Y       \n",
       "14394  Y       \n",
       "14409  Y       \n",
       "16272  Y       \n",
       "16309  Y       \n",
       "16485  Y       \n",
       "16491  Y       \n",
       "17083  Y       \n",
       "29069  Y       \n",
       "19493  Y       \n",
       "19494  Y       \n",
       "21503  Y       \n",
       "21505  Y       \n",
       "24709  Y       \n",
       "24711  Y       \n",
       "25599  Y       \n",
       "25601  Y       \n",
       "17845  Y       \n",
       "26396  Y       \n",
       "17727  Y       \n",
       "26454  Y       \n",
       "17728  Y       \n",
       "26455  Y       \n",
       "17729  Y       \n",
       "26456  Y       \n",
       "17718  Y       \n",
       "26476  Y       \n",
       "17720  Y       \n",
       "26486  Y       \n",
       "17721  Y       \n",
       "26489  Y       \n",
       "17891  Y       \n",
       "26491  Y       \n",
       "17705  Y       \n",
       "26495  Y       \n",
       "17847  Y       \n",
       "26504  Y       \n",
       "17849  Y       \n",
       "26507  Y       \n",
       "31640  Y       \n",
       "31645  Y       \n",
       "31644  Y       \n",
       "31651  Y       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "old_codes_mapping_to_2_new_codes = [code for code, count in old_code_counts.items() if count == 2]\n",
    "\n",
    "with pd.option_context('display.max_rows', None):\n",
    "    display(bnf_mapping[bnf_mapping[\"old_code\"].isin(old_codes_mapping_to_2_new_codes)])"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "There are several patterns here that we can pick out:"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Old \"Liq Spec\" presentation disaggregated into \"oral solution\" and \"oral suspension\" presentations"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>269</th>\n",
       "      <td>0102000L0AAAJAJ</td>\n",
       "      <td>Glycopyrronium Brom_Liq Spec 500mcg/5ml</td>\n",
       "      <td>0102000L0AABHBH</td>\n",
       "      <td>Glycopyrronium bromide 500micrograms/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>271</th>\n",
       "      <td>0102000L0AAAJAJ</td>\n",
       "      <td>Glycopyrronium Brom_Liq Spec 500mcg/5ml</td>\n",
       "      <td>0102000L0AABIBI</td>\n",
       "      <td>Glycopyrronium bromide 500micrograms/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "            old_code                                 old_name  \\\n",
       "269  0102000L0AAAJAJ  Glycopyrronium Brom_Liq Spec 500mcg/5ml   \n",
       "271  0102000L0AAAJAJ  Glycopyrronium Brom_Liq Spec 500mcg/5ml   \n",
       "\n",
       "            new_code  \\\n",
       "269  0102000L0AABHBH   \n",
       "271  0102000L0AABIBI   \n",
       "\n",
       "                                                     new_name changed  \n",
       "269  Glycopyrronium bromide 500micrograms/5ml oral solution    Y       \n",
       "271  Glycopyrronium bromide 500micrograms/5ml oral suspension  Y       "
      ]
     },
     "execution_count": 10,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"old_code\"] == \"0102000L0AAAJAJ\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Old brandend presentation disaggregated into branded and generic presentations"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>10719</th>\n",
       "      <td>070405000BBADA0</td>\n",
       "      <td>Invicorp-2_Inj Soln 1ml Amp</td>\n",
       "      <td>0704050ADAAAAAA</td>\n",
       "      <td>Phentolamine 2mg/0.35ml / Aviptadil 25microg/0.35ml inj amp</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10722</th>\n",
       "      <td>070405000BBADA0</td>\n",
       "      <td>Invicorp-2_Inj Soln 1ml Amp</td>\n",
       "      <td>0704050ADBBABAA</td>\n",
       "      <td>Invicorp 2 solution for injection</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "              old_code                     old_name         new_code  \\\n",
       "10719  070405000BBADA0  Invicorp-2_Inj Soln 1ml Amp  0704050ADAAAAAA   \n",
       "10722  070405000BBADA0  Invicorp-2_Inj Soln 1ml Amp  0704050ADBBABAA   \n",
       "\n",
       "                                                          new_name changed  \n",
       "10719  Phentolamine 2mg/0.35ml / Aviptadil 25microg/0.35ml inj amp  Y       \n",
       "10722  Invicorp 2 solution for injection                            Y       "
      ]
     },
     "execution_count": 11,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"old_code\"] == \"070405000BBADA0\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Old presentation disaggregated into more accurately named presentations"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>14860</th>\n",
       "      <td>0906027G0AAABAB</td>\n",
       "      <td>Vit B Co Strong_Tab</td>\n",
       "      <td>090607000AABBBB</td>\n",
       "      <td>Multivitamin tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15497</th>\n",
       "      <td>0906027G0AAABAB</td>\n",
       "      <td>Vit B Co Strong_Tab</td>\n",
       "      <td>091200000AAFTFT</td>\n",
       "      <td>Multinutrient tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "              old_code             old_name         new_code  \\\n",
       "14860  0906027G0AAABAB  Vit B Co Strong_Tab  090607000AABBBB   \n",
       "15497  0906027G0AAABAB  Vit B Co Strong_Tab  091200000AAFTFT   \n",
       "\n",
       "                    new_name changed  \n",
       "14860  Multivitamin tablets   Y       \n",
       "15497  Multinutrient tablets  Y       "
      ]
     },
     "execution_count": 12,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"old_code\"] == \"0906027G0AAABAB\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Branded appliances into branded presentation and generic presentation in chapter 13"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>17727</th>\n",
       "      <td>21220000234</td>\n",
       "      <td>Cetraben Crm 150g</td>\n",
       "      <td>130201000AACFCF</td>\n",
       "      <td>White soft paraffin 13.2% /Liquid paraffin light 10.5% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26454</th>\n",
       "      <td>21220000234</td>\n",
       "      <td>Cetraben Crm 150g</td>\n",
       "      <td>21220000233</td>\n",
       "      <td>Cetraben cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "          old_code           old_name         new_code  \\\n",
       "17727  21220000234  Cetraben Crm 150g  130201000AACFCF   \n",
       "26454  21220000234  Cetraben Crm 150g  21220000233       \n",
       "\n",
       "                                                           new_name changed  \n",
       "17727  White soft paraffin 13.2% /Liquid paraffin light 10.5% cream  Y       \n",
       "26454  Cetraben cream                                                Y       "
      ]
     },
     "execution_count": 13,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"old_code\"] == \"21220000234\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Old presentation mapping to 112 new codes\n",
    "\n",
    "The old presentation covered a huge range of sizes, colours, and materials.  There is now one presentation for each."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>31251</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263578</td>\n",
       "      <td>Suportx female low waist ostomy girdle small black</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31253</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263579</td>\n",
       "      <td>Suportx female low waist ostomy girdle medium black</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31255</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263580</td>\n",
       "      <td>Suportx female low waist ostomy girdle large black</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31257</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263581</td>\n",
       "      <td>Suportx female low waist ostomy girdle extra large black</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31259</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263582</td>\n",
       "      <td>Suportx female low waist ostomy girdle XX large black</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31261</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263583</td>\n",
       "      <td>Suportx female low waist ostomy girdle small skin</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31263</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263584</td>\n",
       "      <td>Suportx female low waist ostomy girdle medium skin</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31265</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263585</td>\n",
       "      <td>Suportx female low waist ostomy girdle large skin</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31267</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263586</td>\n",
       "      <td>Suportx female low waist ostomy girdle extra large skin</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31269</th>\n",
       "      <td>23300263001</td>\n",
       "      <td>AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)</td>\n",
       "      <td>23300263587</td>\n",
       "      <td>Suportx female low waist ostomy girdle XX large skin</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "          old_code  \\\n",
       "31251  23300263001   \n",
       "31253  23300263001   \n",
       "31255  23300263001   \n",
       "31257  23300263001   \n",
       "31259  23300263001   \n",
       "31261  23300263001   \n",
       "31263  23300263001   \n",
       "31265  23300263001   \n",
       "31267  23300263001   \n",
       "31269  23300263001   \n",
       "\n",
       "                                                           old_name  \\\n",
       "31251  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31253  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31255  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31257  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31259  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31261  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31263  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31265  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31267  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "31269  AMI_Suportx Hernia Support Girdles Fle Low Waist (Sml-XXLge)   \n",
       "\n",
       "          new_code                                                  new_name  \\\n",
       "31251  23300263578  Suportx female low waist ostomy girdle small black         \n",
       "31253  23300263579  Suportx female low waist ostomy girdle medium black        \n",
       "31255  23300263580  Suportx female low waist ostomy girdle large black         \n",
       "31257  23300263581  Suportx female low waist ostomy girdle extra large black   \n",
       "31259  23300263582  Suportx female low waist ostomy girdle XX large black      \n",
       "31261  23300263583  Suportx female low waist ostomy girdle small skin          \n",
       "31263  23300263584  Suportx female low waist ostomy girdle medium skin         \n",
       "31265  23300263585  Suportx female low waist ostomy girdle large skin          \n",
       "31267  23300263586  Suportx female low waist ostomy girdle extra large skin    \n",
       "31269  23300263587  Suportx female low waist ostomy girdle XX large skin       \n",
       "\n",
       "      changed  \n",
       "31251  Y       \n",
       "31253  Y       \n",
       "31255  Y       \n",
       "31257  Y       \n",
       "31259  Y       \n",
       "31261  Y       \n",
       "31263  Y       \n",
       "31265  Y       \n",
       "31267  Y       \n",
       "31269  Y       "
      ]
     },
     "execution_count": 14,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_code = old_code_counts.most_common(1)[0][0]\n",
    "bnf_mapping[bnf_mapping[\"old_code\"] == bnf_code].head(10)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Distribution of numbers of old presentations that are mapped from\n",
    "\n",
    "_(Again, is there a better way to express this?)_"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "There are 1476 distinct new BNF codes:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1476"
      ]
     },
     "execution_count": 15,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping['new_code'].nunique()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "There are 1270 new BNF codes that are mapped to from a single old BNF code, 132 new BNF codes that are mapped to from 2 old BNF codes... and 1 that is mapped to from 13 old BNF codes."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>num_new_codes</th>\n",
       "      <th>num_old_codes_mapped_from</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>1270</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>132</td>\n",
       "      <td>2</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>30</td>\n",
       "      <td>3</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>14</td>\n",
       "      <td>4</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>12</td>\n",
       "      <td>5</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>4</td>\n",
       "      <td>6</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>6</td>\n",
       "      <td>7</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>2</td>\n",
       "      <td>8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>1</td>\n",
       "      <td>13</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>1</td>\n",
       "      <td>14</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>1</td>\n",
       "      <td>19</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>1</td>\n",
       "      <td>23</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>1</td>\n",
       "      <td>24</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>1</td>\n",
       "      <td>31</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "    num_new_codes  num_old_codes_mapped_from\n",
       "0   1270           1                        \n",
       "1   132            2                        \n",
       "2   30             3                        \n",
       "3   14             4                        \n",
       "4   12             5                        \n",
       "5   4              6                        \n",
       "6   6              7                        \n",
       "7   2              8                        \n",
       "8   1              13                       \n",
       "9   1              14                       \n",
       "10  1              19                       \n",
       "11  1              23                       \n",
       "12  1              24                       \n",
       "13  1              31                       "
      ]
     },
     "execution_count": 16,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "new_code_counts = Counter(bnf_mapping['new_code'])\n",
    "new_code_count_distribution = sorted(Counter(new_code_counts.values()).items())\n",
    "rows = [\n",
    "    [num_new_codes, num_old_codes_mapped_from]\n",
    "    for num_old_codes_mapped_from, num_new_codes in new_code_count_distribution\n",
    "]\n",
    "pd.DataFrame(rows, columns=['num_new_codes', 'num_old_codes_mapped_from'])"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### New presentations mapped to from 2 new codes"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>130</th>\n",
       "      <td>0101021B0BEALAG</td>\n",
       "      <td>Gaviscon Ex Strgh_Tab Chble 500mg (Lem)</td>\n",
       "      <td>0101021B0AAAGAG</td>\n",
       "      <td>Generic Gaviscon 500mg chewable tablets sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>131</th>\n",
       "      <td>0101021B0BEAMAG</td>\n",
       "      <td>Gaviscon Ex Strgh_Tab Chble 500mg(P/Mint</td>\n",
       "      <td>0101021B0AAAGAG</td>\n",
       "      <td>Generic Gaviscon 500mg chewable tablets sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>224</th>\n",
       "      <td>0102000ACAAAPAP</td>\n",
       "      <td>Atrop Sulf_Oral Susp 500mcg/5ml</td>\n",
       "      <td>0102000ACAABABA</td>\n",
       "      <td>Atropine 500micrograms/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>226</th>\n",
       "      <td>0102000ACAABBBB</td>\n",
       "      <td>Atrop Sulf_Oral Soln 500mcg/5ml (Old)</td>\n",
       "      <td>0102000ACAABABA</td>\n",
       "      <td>Atropine 500micrograms/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>248</th>\n",
       "      <td>0102000L0AAAWAW</td>\n",
       "      <td>Glycopyrronium Brom_Oral Soln 1mg/5ml</td>\n",
       "      <td>0102000L0AAADAD</td>\n",
       "      <td>Glycopyrronium bromide 1mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>249</th>\n",
       "      <td>0102000L0AAAXAX</td>\n",
       "      <td>Glycopyrronium Brom_Oral Susp 1mg/5ml</td>\n",
       "      <td>0102000L0AAADAD</td>\n",
       "      <td>Glycopyrronium bromide 1mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>254</th>\n",
       "      <td>0102000L0AAAZAZ</td>\n",
       "      <td>Glycopyrronium Brom_Oral Soln 2mg/5ml</td>\n",
       "      <td>0102000L0AAAIAI</td>\n",
       "      <td>Glycopyrronium bromide 2mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>255</th>\n",
       "      <td>0102000L0AABABA</td>\n",
       "      <td>Glycopyrronium Brom_Oral Susp 2mg/5ml</td>\n",
       "      <td>0102000L0AAAIAI</td>\n",
       "      <td>Glycopyrronium bromide 2mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>721</th>\n",
       "      <td>0106010E0AAAHAH</td>\n",
       "      <td>Ispag Husk_Gran Eff Sach 3.5g Orange S/F</td>\n",
       "      <td>0106010E0AAADAD</td>\n",
       "      <td>Ispaghula husk 3.5g efferv gran sach gluten free sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>722</th>\n",
       "      <td>0106010E0AAANAN</td>\n",
       "      <td>Ispag Husk_Gran Eff Sach 3.5g Lem S/F</td>\n",
       "      <td>0106010E0AAADAD</td>\n",
       "      <td>Ispaghula husk 3.5g efferv gran sach gluten free sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>864</th>\n",
       "      <td>0106040M0AAACAC</td>\n",
       "      <td>Macrogol_Co Oral Pdr Sach 6.9g (Plain)</td>\n",
       "      <td>0106040M0AAABAB</td>\n",
       "      <td>Macrogol compound half-strength oral pdr sach NPF sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>865</th>\n",
       "      <td>0106040M0AAAGAG</td>\n",
       "      <td>Macrogol_Co Oral Pdr Sach 6.9g (Choc)S/F</td>\n",
       "      <td>0106040M0AAABAB</td>\n",
       "      <td>Macrogol compound half-strength oral pdr sach NPF sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1222</th>\n",
       "      <td>0202020L0AADJDJ</td>\n",
       "      <td>Furosemide_Oral Soln 5mg/5ml</td>\n",
       "      <td>0202020L0AACACA</td>\n",
       "      <td>Furosemide 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1223</th>\n",
       "      <td>0202020L0AADKDK</td>\n",
       "      <td>Furosemide_Oral Susp 5mg/5ml</td>\n",
       "      <td>0202020L0AACACA</td>\n",
       "      <td>Furosemide 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1818</th>\n",
       "      <td>0205051F0AADVDV</td>\n",
       "      <td>Captopril_Oral Soln 5mg/5ml</td>\n",
       "      <td>0205051F0AABNBN</td>\n",
       "      <td>Captopril 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1819</th>\n",
       "      <td>0205051F0AADWDW</td>\n",
       "      <td>Captopril_Oral Susp 5mg/5ml</td>\n",
       "      <td>0205051F0AABNBN</td>\n",
       "      <td>Captopril 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1824</th>\n",
       "      <td>0205051F0AADXDX</td>\n",
       "      <td>Captopril_Oral Soln 25mg/5ml</td>\n",
       "      <td>0205051F0AABWBW</td>\n",
       "      <td>Captopril 25mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1825</th>\n",
       "      <td>0205051F0AADYDY</td>\n",
       "      <td>Captopril_Oral Susp 25mg/5ml</td>\n",
       "      <td>0205051F0AABWBW</td>\n",
       "      <td>Captopril 25mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1903</th>\n",
       "      <td>0205051L0AAAUAU</td>\n",
       "      <td>Lisinopril_Oral Soln 5mg/5ml</td>\n",
       "      <td>0205051L0AAAGAG</td>\n",
       "      <td>Lisinopril 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1904</th>\n",
       "      <td>0205051L0AAAVAV</td>\n",
       "      <td>Lisinopril_Oral Susp 5mg/5ml</td>\n",
       "      <td>0205051L0AAAGAG</td>\n",
       "      <td>Lisinopril 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1907</th>\n",
       "      <td>0205051L0AAAWAW</td>\n",
       "      <td>Lisinopril_Oral Soln 2.5mg/5ml</td>\n",
       "      <td>0205051L0AAAIAI</td>\n",
       "      <td>Lisinopril 2.5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1908</th>\n",
       "      <td>0205051L0AAAXAX</td>\n",
       "      <td>Lisinopril_Oral Susp 2.5mg/5ml</td>\n",
       "      <td>0205051L0AAAIAI</td>\n",
       "      <td>Lisinopril 2.5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1961</th>\n",
       "      <td>0205051R0AAAXAX</td>\n",
       "      <td>Ramipril_Oral Soln 5mg/5ml</td>\n",
       "      <td>0205051R0AAAEAE</td>\n",
       "      <td>Ramipril 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1962</th>\n",
       "      <td>0205051R0AAAYAY</td>\n",
       "      <td>Ramipril_Oral Susp 5mg/5ml</td>\n",
       "      <td>0205051R0AAAEAE</td>\n",
       "      <td>Ramipril 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2197</th>\n",
       "      <td>0206010F0BFADCI</td>\n",
       "      <td>Nitrolingual_P/Spy 400mcg (180 D)</td>\n",
       "      <td>0206010F0BFABCJ</td>\n",
       "      <td>Nitrolingual 400micrograms/dose pump sublingual spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2198</th>\n",
       "      <td>0206010F0BFAECK</td>\n",
       "      <td>Nitrolingual_P/Spy 400mcg (75 D)</td>\n",
       "      <td>0206010F0BFABCJ</td>\n",
       "      <td>Nitrolingual 400micrograms/dose pump sublingual spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2305</th>\n",
       "      <td>0206020A0AAAQAQ</td>\n",
       "      <td>Amlodipine_Oral Soln 5mg/5ml</td>\n",
       "      <td>0206020A0AAACAC</td>\n",
       "      <td>Amlodipine 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2306</th>\n",
       "      <td>0206020A0AAARAR</td>\n",
       "      <td>Amlodipine_Oral Susp 5mg/5ml</td>\n",
       "      <td>0206020A0AAACAC</td>\n",
       "      <td>Amlodipine 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2308</th>\n",
       "      <td>0206020A0AAAPAP</td>\n",
       "      <td>Amlodipine_Oral Susp 10mg/5ml</td>\n",
       "      <td>0206020A0AAADAD</td>\n",
       "      <td>Amlodipine 10mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2309</th>\n",
       "      <td>0206020A0AAASAS</td>\n",
       "      <td>Amlodipine_Oral Soln 10mg/5ml</td>\n",
       "      <td>0206020A0AAADAD</td>\n",
       "      <td>Amlodipine 10mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2875</th>\n",
       "      <td>0209000L0AAANAN</td>\n",
       "      <td>Dipyridamole_Oral Soln 200mg/5ml</td>\n",
       "      <td>0209000L0AAAZAZ</td>\n",
       "      <td>Dipyridamole 200mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2876</th>\n",
       "      <td>0209000L0AAAXAX</td>\n",
       "      <td>Dipyridamole_Oral Susp 200mg/5ml (Old)</td>\n",
       "      <td>0209000L0AAAZAZ</td>\n",
       "      <td>Dipyridamole 200mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3133</th>\n",
       "      <td>0301011R0AABYBY</td>\n",
       "      <td>Salbutamol_Pdr For Inh 200mcg (100 D)</td>\n",
       "      <td>0301011R0AAAQAQ</td>\n",
       "      <td>Salbutamol 200micrograms/dose dry powder inhaler</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3134</th>\n",
       "      <td>0301011R0AACACA</td>\n",
       "      <td>Salbutamol_Pdr For Inh 200mcg (200 D)</td>\n",
       "      <td>0301011R0AAAQAQ</td>\n",
       "      <td>Salbutamol 200micrograms/dose dry powder inhaler</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3774</th>\n",
       "      <td>0304030C0AAALAL</td>\n",
       "      <td>Adren_Inj 1/1000 1ml Pfs (21 Gauge)</td>\n",
       "      <td>0304030C0AAAYAY</td>\n",
       "      <td>Adrenaline (base) 1mg/1ml (1 in 1,000) inj pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3775</th>\n",
       "      <td>0304030C0AAAWAW</td>\n",
       "      <td>Adren_Inj 1/1000 1ml Pfs (25 Gauge)</td>\n",
       "      <td>0304030C0AAAYAY</td>\n",
       "      <td>Adrenaline (base) 1mg/1ml (1 in 1,000) inj pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4138</th>\n",
       "      <td>0401010ADAABXBX</td>\n",
       "      <td>Melatonin_Oral Susp 5mg/5ml (Old)</td>\n",
       "      <td>0401010ADAADEDE</td>\n",
       "      <td>Melatonin 5mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4139</th>\n",
       "      <td>0401010ADAADBDB</td>\n",
       "      <td>Melatonin_Oral Susp 5mg/5ml</td>\n",
       "      <td>0401010ADAADEDE</td>\n",
       "      <td>Melatonin 5mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4162</th>\n",
       "      <td>0401010B0AABUBU</td>\n",
       "      <td>Chloral Hydrate_Oral Soln 200mg/5ml BP</td>\n",
       "      <td>0401010B0AABGBG</td>\n",
       "      <td>Chloral hydrate 200mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4163</th>\n",
       "      <td>0401010B0AABVBV</td>\n",
       "      <td>Chloral Hydrate_Oral Susp 200mg/5ml</td>\n",
       "      <td>0401010B0AABGBG</td>\n",
       "      <td>Chloral hydrate 200mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4567</th>\n",
       "      <td>0402010J0AABLBL</td>\n",
       "      <td>Haloperidol_Oral Soln 1mg/5ml</td>\n",
       "      <td>0402010J0AAA7A7</td>\n",
       "      <td>Haloperidol 1mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4568</th>\n",
       "      <td>0402010J0AABMBM</td>\n",
       "      <td>Haloperidol_Oral Susp 1mg/5ml</td>\n",
       "      <td>0402010J0AAA7A7</td>\n",
       "      <td>Haloperidol 1mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4783</th>\n",
       "      <td>0403010B0AABHBH</td>\n",
       "      <td>Amitriptyline HCl_Oral Soln 10mg/5ml</td>\n",
       "      <td>0403010B0AAA6A6</td>\n",
       "      <td>Amitriptyline 10mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4784</th>\n",
       "      <td>0403010B0AABIBI</td>\n",
       "      <td>Amitriptyline HCl_Oral Susp 10mg/5ml</td>\n",
       "      <td>0403010B0AAA6A6</td>\n",
       "      <td>Amitriptyline 10mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5127</th>\n",
       "      <td>0404000L0AABKBK</td>\n",
       "      <td>Dexamfet Sulf_Oral Soln 5mg/5ml</td>\n",
       "      <td>0404000L0AAAMAM</td>\n",
       "      <td>Dexamfetamine 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5128</th>\n",
       "      <td>0404000L0AABLBL</td>\n",
       "      <td>Dexamfet Sulf_Oral Susp 5mg/5ml</td>\n",
       "      <td>0404000L0AAAMAM</td>\n",
       "      <td>Dexamfetamine 5mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5214</th>\n",
       "      <td>0404000R0AAADAD</td>\n",
       "      <td>Modafinil_Oral Soln 100mg/5ml</td>\n",
       "      <td>0404000R0AAAGAG</td>\n",
       "      <td>Modafinil 100mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5215</th>\n",
       "      <td>0404000R0AAAEAE</td>\n",
       "      <td>Modafinil_Oral Susp 100mg/5ml (Old)</td>\n",
       "      <td>0404000R0AAAGAG</td>\n",
       "      <td>Modafinil 100mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5871</th>\n",
       "      <td>0407020A0AABIBI</td>\n",
       "      <td>Fentanyl_Nsl Spy 50mcg (20D)</td>\n",
       "      <td>0407020A0AABHBH</td>\n",
       "      <td>Fentanyl 50micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5872</th>\n",
       "      <td>0407020A0AABSBS</td>\n",
       "      <td>Fentanyl_Nsl Spy 50mcg/0.1ml Ud (6D)</td>\n",
       "      <td>0407020A0AABHBH</td>\n",
       "      <td>Fentanyl 50micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5878</th>\n",
       "      <td>0407020A0AABMBM</td>\n",
       "      <td>Fentanyl_Nsl Spy 200mcg (20D)</td>\n",
       "      <td>0407020A0AABLBL</td>\n",
       "      <td>Fentanyl 200micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5879</th>\n",
       "      <td>0407020A0AABQBQ</td>\n",
       "      <td>Fentanyl_Nsl Spy 200mcg/0.1ml Ud (6D)</td>\n",
       "      <td>0407020A0AABLBL</td>\n",
       "      <td>Fentanyl 200micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5946</th>\n",
       "      <td>0407020A0BNAEBL</td>\n",
       "      <td>Instanyl_Nsl Spy 200mcg (10D)</td>\n",
       "      <td>0407020A0BNAGBQ</td>\n",
       "      <td>Instanyl 200micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5947</th>\n",
       "      <td>0407020A0BNAFBM</td>\n",
       "      <td>Instanyl_Nsl Spy 200mcg (20D)</td>\n",
       "      <td>0407020A0BNAGBQ</td>\n",
       "      <td>Instanyl 200micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5949</th>\n",
       "      <td>0407020A0BNACBJ</td>\n",
       "      <td>Instanyl_Nsl Spy 100mcg (10D)</td>\n",
       "      <td>0407020A0BNAHBR</td>\n",
       "      <td>Instanyl 100micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5950</th>\n",
       "      <td>0407020A0BNADBK</td>\n",
       "      <td>Instanyl_Nsl Spy 100mcg (20D)</td>\n",
       "      <td>0407020A0BNAHBR</td>\n",
       "      <td>Instanyl 100micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5952</th>\n",
       "      <td>0407020A0BNAABH</td>\n",
       "      <td>Instanyl_Nsl Spy 50mcg (10D)</td>\n",
       "      <td>0407020A0BNAIBS</td>\n",
       "      <td>Instanyl 50micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5953</th>\n",
       "      <td>0407020A0BNABBI</td>\n",
       "      <td>Instanyl_Nsl Spy 50mcg (20D)</td>\n",
       "      <td>0407020A0BNAIBS</td>\n",
       "      <td>Instanyl 50micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6501</th>\n",
       "      <td>0407042F0AAATAT</td>\n",
       "      <td>Clonidine HCl_Oral Soln 50mcg/5ml (DT)</td>\n",
       "      <td>0407042F0AAAFAF</td>\n",
       "      <td>Clonidine 50micrograms/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6502</th>\n",
       "      <td>0407042F0AAAUAU</td>\n",
       "      <td>Clonidine HCl_Oral Susp 50mcg/5ml (DT)</td>\n",
       "      <td>0407042F0AAAFAF</td>\n",
       "      <td>Clonidine 50micrograms/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6568</th>\n",
       "      <td>040801050AAAZAZ</td>\n",
       "      <td>Topiramate_Oral Susp 100mg/5ml</td>\n",
       "      <td>040801050AACCCC</td>\n",
       "      <td>Topiramate 100mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6569</th>\n",
       "      <td>040801050AACACA</td>\n",
       "      <td>Topiramate_Oral Soln 100mg/5ml (DT Old)</td>\n",
       "      <td>040801050AACCCC</td>\n",
       "      <td>Topiramate 100mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6917</th>\n",
       "      <td>0408010H0BBAHAC</td>\n",
       "      <td>Lamictal_Tab 25mg (Monotherapy)</td>\n",
       "      <td>0408010H0BBACAC</td>\n",
       "      <td>Lamictal 25mg tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6918</th>\n",
       "      <td>0408010H0BBAIAC</td>\n",
       "      <td>Lamictal_Tab 25mg (Valpr)</td>\n",
       "      <td>0408010H0BBACAC</td>\n",
       "      <td>Lamictal 25mg tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6939</th>\n",
       "      <td>0408010N0AAEUEU</td>\n",
       "      <td>Phenobarb_Oral Soln 50mg/5ml</td>\n",
       "      <td>0408010N0AACLCL</td>\n",
       "      <td>Phenobarbital 50mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6940</th>\n",
       "      <td>0408010N0AAEVEV</td>\n",
       "      <td>Phenobarb_Oral Susp 50mg/5ml</td>\n",
       "      <td>0408010N0AACLCL</td>\n",
       "      <td>Phenobarbital 50mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6995</th>\n",
       "      <td>0408010U0AAAAAA</td>\n",
       "      <td>Primidone_Oral Susp 250mg/5ml (Old)</td>\n",
       "      <td>0408010U0AABCBC</td>\n",
       "      <td>Primidone 250mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6996</th>\n",
       "      <td>0408010U0AAAMAM</td>\n",
       "      <td>Primidone_Oral Susp 250mg/5ml (Spec)</td>\n",
       "      <td>0408010U0AABCBC</td>\n",
       "      <td>Primidone 250mg/5ml oral suspension</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7350</th>\n",
       "      <td>0409020C0AAAMAM</td>\n",
       "      <td>Trihexyphenidyl HCl_Oral Soln 2mg/5ml</td>\n",
       "      <td>0409020C0AAALAL</td>\n",
       "      <td>Trihexyphenidyl 2mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7351</th>\n",
       "      <td>0409020C0AAANAN</td>\n",
       "      <td>Trihexyphenidyl HCl_Oral Susp 2mg/5ml</td>\n",
       "      <td>0409020C0AAALAL</td>\n",
       "      <td>Trihexyphenidyl 2mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7454</th>\n",
       "      <td>0410020B0AABVBV</td>\n",
       "      <td>Nicotine_Loz 1.5mg S/F (Cherry)</td>\n",
       "      <td>0410020B0AABPBP</td>\n",
       "      <td>Nicotine 1.5mg lozenges sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7455</th>\n",
       "      <td>0410020B0AACBCB</td>\n",
       "      <td>Nicotine_Loz 1.5mg S/F (Orange)</td>\n",
       "      <td>0410020B0AABPBP</td>\n",
       "      <td>Nicotine 1.5mg lozenges sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8891</th>\n",
       "      <td>0601012D0AAAVAV</td>\n",
       "      <td>Gppe Ins_Humulin M3 Humaject 3ml Pf Pen</td>\n",
       "      <td>0601012D0AABZBZ</td>\n",
       "      <td>Insulin isoph biphas hum 30/70 100u/ml inj 3ml pf dispos dev</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8892</th>\n",
       "      <td>0601012D0AABABA</td>\n",
       "      <td>Ins Bip Isophane_30/70 100u/ml 3ml Cart</td>\n",
       "      <td>0601012D0AABZBZ</td>\n",
       "      <td>Insulin isoph biphas hum 30/70 100u/ml inj 3ml pf dispos dev</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10318</th>\n",
       "      <td>0702020H0AAABAB</td>\n",
       "      <td>Econazole Nit_Pess 150mg + Applic</td>\n",
       "      <td>0702020H0AAAFAF</td>\n",
       "      <td>Econazole 150mg pessaries</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10319</th>\n",
       "      <td>0702020H0AAAEAE</td>\n",
       "      <td>Econazole Nit_Pess 150mg + Applic</td>\n",
       "      <td>0702020H0AAAFAF</td>\n",
       "      <td>Econazole 150mg pessaries</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10610</th>\n",
       "      <td>0704020J0AAAIAI</td>\n",
       "      <td>Oxybutynin HCl_Oral Soln 2.5mg/5ml (Old)</td>\n",
       "      <td>0704020J0AAAZAZ</td>\n",
       "      <td>Oxybutynin 2.5mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10611</th>\n",
       "      <td>0704020J0AAAKAK</td>\n",
       "      <td>Oxybutynin HCl_Oral Susp 2.5mg/5ml</td>\n",
       "      <td>0704020J0AAAZAZ</td>\n",
       "      <td>Oxybutynin 2.5mg/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11831</th>\n",
       "      <td>0902012L0AABRBR</td>\n",
       "      <td>Sod Chlor_Liq Spec 292.5mg/5ml</td>\n",
       "      <td>0902012L0AADDDD</td>\n",
       "      <td>Sodium chloride 292.5mg/5ml (1mmol/ml) oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11832</th>\n",
       "      <td>0902012L0AADCDC</td>\n",
       "      <td>Sod Chlor_Oral Soln 292.5mg/5ml S/F</td>\n",
       "      <td>0902012L0AADDDD</td>\n",
       "      <td>Sodium chloride 292.5mg/5ml (1mmol/ml) oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11836</th>\n",
       "      <td>0902012L0AABCBC</td>\n",
       "      <td>Sod Chlor_Liq Spec 1.46g/5ml</td>\n",
       "      <td>0902012L0AADHDH</td>\n",
       "      <td>Sodium chloride 1.46g/5ml (5mmol/ml) oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11837</th>\n",
       "      <td>0902012L0AADEDE</td>\n",
       "      <td>Sod Chlor_Oral Soln 1.46g/5ml (DT Old)</td>\n",
       "      <td>0902012L0AADHDH</td>\n",
       "      <td>Sodium chloride 1.46g/5ml (5mmol/ml) oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11966</th>\n",
       "      <td>0902021S0AADBDB</td>\n",
       "      <td>Glucose/Sod Chlor_I/V Inf5%/0.9%500ml@gn</td>\n",
       "      <td>0902021S0AABDBD</td>\n",
       "      <td>Sodium chloride 0.9% / Glucose 5% infusion 500ml bags</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11967</th>\n",
       "      <td>0902021S0BDAIBD</td>\n",
       "      <td>Steriflex_No3 Gluc5%/SodChlor.9%Inf500ml</td>\n",
       "      <td>0902021S0AABDBD</td>\n",
       "      <td>Sodium chloride 0.9% / Glucose 5% infusion 500ml bags</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12163</th>\n",
       "      <td>090401000BBJGA0</td>\n",
       "      <td>Calogen_Emuls (Sbery)</td>\n",
       "      <td>090401000AABABA</td>\n",
       "      <td>Generic Calogen emulsion</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12164</th>\n",
       "      <td>090401000BBLKA0</td>\n",
       "      <td>Calogen_Emuls (Banana)</td>\n",
       "      <td>090401000AABABA</td>\n",
       "      <td>Generic Calogen emulsion</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12169</th>\n",
       "      <td>090401000BBJFA0</td>\n",
       "      <td>Neocate Advance_Pdr Sach 100g (Unflav)</td>\n",
       "      <td>090401000AACHCH</td>\n",
       "      <td>Neocate Advance powder sachets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12170</th>\n",
       "      <td>090401000BBLDA0</td>\n",
       "      <td>Neocate Advance_Pdr Sach 50g (Flav)</td>\n",
       "      <td>090401000AACHCH</td>\n",
       "      <td>Neocate Advance powder sachets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12669</th>\n",
       "      <td>0904010I0AABJBJ</td>\n",
       "      <td>G/F_Bisc</td>\n",
       "      <td>0904010A0AABFBF</td>\n",
       "      <td>Gluten free biscuits</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12670</th>\n",
       "      <td>0904010U0AAAAAA</td>\n",
       "      <td>G/F /W/F_Bread</td>\n",
       "      <td>0904010A0AABFBF</td>\n",
       "      <td>Gluten free biscuits</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12867</th>\n",
       "      <td>090401060AAACAC</td>\n",
       "      <td>G/F /L/P_Meals</td>\n",
       "      <td>0904010AQAAAAAA</td>\n",
       "      <td>Low protein pasta</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12869</th>\n",
       "      <td>0904010T0AAADAD</td>\n",
       "      <td>G/F /L/P_Pasta</td>\n",
       "      <td>0904010AQAAAAAA</td>\n",
       "      <td>Low protein pasta</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13272</th>\n",
       "      <td>090402000BBCEA0</td>\n",
       "      <td>Peptamen_Liq Diet (Vanilla)</td>\n",
       "      <td>090402000AAASAS</td>\n",
       "      <td>Generic Peptamen liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13273</th>\n",
       "      <td>090402000BBKLA0</td>\n",
       "      <td>Peptamen_Dripac-Flex Liq (Unflav)</td>\n",
       "      <td>090402000AAASAS</td>\n",
       "      <td>Generic Peptamen liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13274</th>\n",
       "      <td>090402000BBDMA0</td>\n",
       "      <td>Seravit_Paed Mix Unflav</td>\n",
       "      <td>090402000AAATAT</td>\n",
       "      <td>Generic Seravit Paediatric powder</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13275</th>\n",
       "      <td>090402000BBDNA0</td>\n",
       "      <td>Seravit_Paed Mix P/Apple</td>\n",
       "      <td>090402000AAATAT</td>\n",
       "      <td>Generic Seravit Paediatric powder</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13334</th>\n",
       "      <td>090402000BBMJA0</td>\n",
       "      <td>Optifibre_Pdr Sach 8g</td>\n",
       "      <td>090402000BBHWA0</td>\n",
       "      <td>Optifibre powder</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13335</th>\n",
       "      <td>090402000BBSKA0</td>\n",
       "      <td>Optifibre_Pdr Sach 10g</td>\n",
       "      <td>090402000BBHWA0</td>\n",
       "      <td>Optifibre powder</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13601</th>\n",
       "      <td>090402000BBTFA0</td>\n",
       "      <td>Pro-Cal_Shot S/Pack 750ml</td>\n",
       "      <td>090402000BBWUA0</td>\n",
       "      <td>Pro-Cal shot starter pack</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13602</th>\n",
       "      <td>090402000BBVZA0</td>\n",
       "      <td>Pro-Cal_Shot S/Pack 240ml</td>\n",
       "      <td>090402000BBWUA0</td>\n",
       "      <td>Pro-Cal shot starter pack</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13804</th>\n",
       "      <td>0905013G0AABXBX</td>\n",
       "      <td>Mag Glycerophos_Oral Soln97.2mg/5ml(Old)</td>\n",
       "      <td>0905013G0AADCDC</td>\n",
       "      <td>Mag glycerophos (mag 97.2mg/5ml (4mmol/5ml)) soln</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13806</th>\n",
       "      <td>0905013G0AADIDI</td>\n",
       "      <td>Mag Glycerophos_Oral Soln 97.2mg/5ml</td>\n",
       "      <td>0905013G0AADCDC</td>\n",
       "      <td>Mag glycerophos (mag 97.2mg/5ml (4mmol/5ml)) soln</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13810</th>\n",
       "      <td>0905013G0AACVCV</td>\n",
       "      <td>Mag Glycerophos_OralSoln121.25mg/5ml Old</td>\n",
       "      <td>0905013G0AADFDF</td>\n",
       "      <td>Mag glycerophos (mag 121.25mg/5ml (5mmol/5ml)) soln</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13812</th>\n",
       "      <td>0905013G0AADGDG</td>\n",
       "      <td>Mag Glycerophos_OralSoln121.25mg/5mlSpec</td>\n",
       "      <td>0905013G0AADFDF</td>\n",
       "      <td>Mag glycerophos (mag 121.25mg/5ml (5mmol/5ml)) soln</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13935</th>\n",
       "      <td>090504100BBBRBB</td>\n",
       "      <td>Lamb_Zn (Cit) Cap 50mg (8283)</td>\n",
       "      <td>090504100AABBBB</td>\n",
       "      <td>Zinc citrate 50mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13936</th>\n",
       "      <td>090504100BBHDBB</td>\n",
       "      <td>Vega_Zn Cit V/Cap 50mg</td>\n",
       "      <td>090504100AABBBB</td>\n",
       "      <td>Zinc citrate 50mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13964</th>\n",
       "      <td>090504700BBDGBC</td>\n",
       "      <td>Solgar_Selenium Tab 200mcg</td>\n",
       "      <td>090504700AABCBC</td>\n",
       "      <td>Selenium 200microgram tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13965</th>\n",
       "      <td>090504700BBFDBC</td>\n",
       "      <td>HealthAid_Selenium Tab 200mcg</td>\n",
       "      <td>090504700AABCBC</td>\n",
       "      <td>Selenium 200microgram tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13967</th>\n",
       "      <td>090504700BBDNBJ</td>\n",
       "      <td>Solgar_Selenium Tab 100mcg</td>\n",
       "      <td>090504700AABJBJ</td>\n",
       "      <td>Selenium 100microgram tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13968</th>\n",
       "      <td>090504700BBDXA0</td>\n",
       "      <td>Cytoplan_Selenium Tab 100mcg</td>\n",
       "      <td>090504700AABJBJ</td>\n",
       "      <td>Selenium 100microgram tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14279</th>\n",
       "      <td>0906031C0CHABBI</td>\n",
       "      <td>BioCare_Vit C Cap 500mg</td>\n",
       "      <td>0906031C0AABIBI</td>\n",
       "      <td>Ascorbic acid 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14280</th>\n",
       "      <td>0906031C0CJAABI</td>\n",
       "      <td>Solgar_Vit C V/Cap 500mg</td>\n",
       "      <td>0906031C0AABIBI</td>\n",
       "      <td>Ascorbic acid 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14368</th>\n",
       "      <td>0906040G0AACACA</td>\n",
       "      <td>Colecal &amp; Calc_Tab Chble 400u/1.5g (Lem)</td>\n",
       "      <td>0906040G0AABYBY</td>\n",
       "      <td>Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14369</th>\n",
       "      <td>0906040G0AACECE</td>\n",
       "      <td>Colecal &amp; Calc_Tab Chble 400u/1.5g</td>\n",
       "      <td>0906040G0AABYBY</td>\n",
       "      <td>Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14409</th>\n",
       "      <td>0906040G0AAAUAU</td>\n",
       "      <td>Colecal_Oral Susp 15,000u/5ml</td>\n",
       "      <td>0906040G0AADSDS</td>\n",
       "      <td>Colecalciferol 15,000units/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14410</th>\n",
       "      <td>0906040G0AACMCM</td>\n",
       "      <td>Colecal_Oral Soln 15,000u/5ml (Old)</td>\n",
       "      <td>0906040G0AADSDS</td>\n",
       "      <td>Colecalciferol 15,000units/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14754</th>\n",
       "      <td>0906050P0CPADA9</td>\n",
       "      <td>Natures Aid_Natur Vit ESoftgelsCap1,000u</td>\n",
       "      <td>0906050P0AAA9A9</td>\n",
       "      <td>Vitamin E 1,000unit capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14755</th>\n",
       "      <td>0906050P0CWAFA9</td>\n",
       "      <td>Solgar_Vit E Cap 1,000u</td>\n",
       "      <td>0906050P0AAA9A9</td>\n",
       "      <td>Vitamin E 1,000unit capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14765</th>\n",
       "      <td>0906050P0CWAAAF</td>\n",
       "      <td>Solgar_Vit E Mixed Soft Gel 400u (268mg)</td>\n",
       "      <td>0906050P0AAAFAF</td>\n",
       "      <td>Vitamin E 400unit capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14766</th>\n",
       "      <td>0906050P0CWABAF</td>\n",
       "      <td>Solgar_Vit E Dry V/Cap 400u (268mg)</td>\n",
       "      <td>0906050P0AAAFAF</td>\n",
       "      <td>Vitamin E 400unit capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15247</th>\n",
       "      <td>091101000BBPXFF</td>\n",
       "      <td>Quest_L-Glutamine Cap 500mg</td>\n",
       "      <td>091101000AAFFFF</td>\n",
       "      <td>Glutamine 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15248</th>\n",
       "      <td>091101000BBQPFF</td>\n",
       "      <td>Solgar_L-Glutamine V/Cap 500mg</td>\n",
       "      <td>091101000AAFFFF</td>\n",
       "      <td>Glutamine 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15255</th>\n",
       "      <td>091101000BBCHFP</td>\n",
       "      <td>Lamb_L-Phenylalanine Cap 500mg (8321)</td>\n",
       "      <td>091101000AAFPFP</td>\n",
       "      <td>L-Phenylalanine 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15256</th>\n",
       "      <td>091101000BBPLFP</td>\n",
       "      <td>Quest_L-Phenylalanine Cap 500mg</td>\n",
       "      <td>091101000AAFPFP</td>\n",
       "      <td>L-Phenylalanine 500mg capsules</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15431</th>\n",
       "      <td>091200000BETEEE</td>\n",
       "      <td>NatraHealth_Glucosam+Chond Cap 400/100mg</td>\n",
       "      <td>091200000AAEEEE</td>\n",
       "      <td>Glucosamine sulfate 400mg / Chondroitin sulfate 100mg caps</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15432</th>\n",
       "      <td>091200000BEWHEE</td>\n",
       "      <td>BR Pharm_Glucosamine + Chondroitin Cap</td>\n",
       "      <td>091200000AAEEEE</td>\n",
       "      <td>Glucosamine sulfate 400mg / Chondroitin sulfate 100mg caps</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15452</th>\n",
       "      <td>091200000BEIPFE</td>\n",
       "      <td>HealthAid_MSM Tab 1g</td>\n",
       "      <td>091200000AAFEFE</td>\n",
       "      <td>Dimethyl sulfone 1g / Ascorbic acid 60mg tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15453</th>\n",
       "      <td>091200000BFSAFE</td>\n",
       "      <td>H/Nature_MSM Tab 1000mg</td>\n",
       "      <td>091200000AAFEFE</td>\n",
       "      <td>Dimethyl sulfone 1g / Ascorbic acid 60mg tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16272</th>\n",
       "      <td>1001030U0AABTBT</td>\n",
       "      <td>Methotrexate_Oral Soln 10mg/5ml</td>\n",
       "      <td>1001030U0AAAHAH</td>\n",
       "      <td>Methotrexate 10mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16273</th>\n",
       "      <td>1001030U0AABUBU</td>\n",
       "      <td>Methotrexate_Oral Susp 10mg/5ml</td>\n",
       "      <td>1001030U0AAAHAH</td>\n",
       "      <td>Methotrexate 10mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16416</th>\n",
       "      <td>1001050A0BFAGAB</td>\n",
       "      <td>Natures Aid_Veget Glucosam HCl Tab 750mg</td>\n",
       "      <td>1001050A0AAABAB</td>\n",
       "      <td>Glucosamine hydrochloride 750mg tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16417</th>\n",
       "      <td>1001050A0BKAAAB</td>\n",
       "      <td>Health+Plus_Glucosamine HCl Tab 750mg</td>\n",
       "      <td>1001050A0AAABAB</td>\n",
       "      <td>Glucosamine hydrochloride 750mg tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16784</th>\n",
       "      <td>1104010I0AAACAC</td>\n",
       "      <td>Dexameth_Eye Dps 0.1% P/F (Old)</td>\n",
       "      <td>1104010I0AAAUAU</td>\n",
       "      <td>Dexamethasone 0.1% eye drops preservative free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16785</th>\n",
       "      <td>1104010I0AAASAS</td>\n",
       "      <td>Dexameth_Eye Dps 0.1% P/F (DT Old)</td>\n",
       "      <td>1104010I0AAAUAU</td>\n",
       "      <td>Dexamethasone 0.1% eye drops preservative free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17039</th>\n",
       "      <td>1106000X0AAAAAA</td>\n",
       "      <td>Piloc HCl_Eye Dps 0.5% (DT Old)</td>\n",
       "      <td>1106000X0AABPBP</td>\n",
       "      <td>Pilocarpine hydrochloride 0.5% eye drops</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17040</th>\n",
       "      <td>1106000X0AABGBG</td>\n",
       "      <td>Piloc HCl_Eye Dps 0.5% P/F</td>\n",
       "      <td>1106000X0AABPBP</td>\n",
       "      <td>Pilocarpine hydrochloride 0.5% eye drops</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17133</th>\n",
       "      <td>1108010C0AAAEAE</td>\n",
       "      <td>Acetylcy_Eye Dps 10%</td>\n",
       "      <td>1108010C0AABABA</td>\n",
       "      <td>Acetylcysteine 10% eye drops preservative free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17134</th>\n",
       "      <td>1108010C0AAAPAP</td>\n",
       "      <td>Acetylcy_Eye Dps 10% P/F (DT Old)</td>\n",
       "      <td>1108010C0AABABA</td>\n",
       "      <td>Acetylcysteine 10% eye drops preservative free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17168</th>\n",
       "      <td>21300000191</td>\n",
       "      <td>Sai-Meds Hypromellose 0.5% Eye Dps 10ml</td>\n",
       "      <td>1108010F0AAABAB</td>\n",
       "      <td>Hypromellose 0.5% eye drops</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17169</th>\n",
       "      <td>21300000309</td>\n",
       "      <td>Teardew 0.5% Hypromellose Eye Dps 10ml</td>\n",
       "      <td>1108010F0AAABAB</td>\n",
       "      <td>Hypromellose 0.5% eye drops</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17175</th>\n",
       "      <td>21300000119</td>\n",
       "      <td>Tear-Lac Hypromellose Eye Dps 0.3% P/F</td>\n",
       "      <td>1108010F0AAANAN</td>\n",
       "      <td>Hypromellose 0.3% eye drops preservative free (drug)</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17176</th>\n",
       "      <td>21300000159</td>\n",
       "      <td>PF Drops Hypromellose 0.3% Eye Dps 10ml P/F</td>\n",
       "      <td>1108010F0AAANAN</td>\n",
       "      <td>Hypromellose 0.3% eye drops preservative free (drug)</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17198</th>\n",
       "      <td>1108010K0AACECE</td>\n",
       "      <td>Sod Chlor_Eye Dps 5% P/F</td>\n",
       "      <td>1108010K0AAA6A6</td>\n",
       "      <td>Sodium chloride 5% eye drops preservative free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17199</th>\n",
       "      <td>21300000133</td>\n",
       "      <td>PF Drops Sod Chlor 5% Eye Dps 10ml P/F</td>\n",
       "      <td>1108010K0AAA6A6</td>\n",
       "      <td>Sodium chloride 5% eye drops preservative free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17346</th>\n",
       "      <td>1202010C0AAACAC</td>\n",
       "      <td>Beclomet Diprop_Aq Nsl Spy 50mcg (100 D)</td>\n",
       "      <td>1202010C0AAAAAA</td>\n",
       "      <td>Beclometasone 50micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17347</th>\n",
       "      <td>1202010C0AAADAD</td>\n",
       "      <td>Beclomet Diprop_Nsl Spy 50mcg (180 D)</td>\n",
       "      <td>1202010C0AAAAAA</td>\n",
       "      <td>Beclometasone 50micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17360</th>\n",
       "      <td>1202010I0AAADAD</td>\n",
       "      <td>Budesonide_Aq Nsl Spy 100mcg (200D)</td>\n",
       "      <td>1202010I0AAACAC</td>\n",
       "      <td>Budesonide 100micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17361</th>\n",
       "      <td>1202010I0AAAGAG</td>\n",
       "      <td>Budesonide_Aq Nsl Spy 100mcg (150D)</td>\n",
       "      <td>1202010I0AAACAC</td>\n",
       "      <td>Budesonide 100micrograms/dose nasal spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17520</th>\n",
       "      <td>1203030A0AAAAAA</td>\n",
       "      <td>Dichlor Alc/Amylmet_Loz 1.2mg/600mcg</td>\n",
       "      <td>1203030A0AAAEAE</td>\n",
       "      <td>Amylmetacresol 600microgram lozenges</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17521</th>\n",
       "      <td>1203030A0BJAAAA</td>\n",
       "      <td>Throaties_A-Bact Pastil(R/Currant&amp;R/Hip)</td>\n",
       "      <td>1203030A0AAAEAE</td>\n",
       "      <td>Amylmetacresol 600microgram lozenges</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17621</th>\n",
       "      <td>1203040E0AAACAC</td>\n",
       "      <td>Chlorhex Glucon_Mthwsh (Mint) 0.2%</td>\n",
       "      <td>1203040E0AAABAB</td>\n",
       "      <td>Chlorhexidine gluconate 0.2% mouthwash</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17622</th>\n",
       "      <td>1203040E0AAAGAG</td>\n",
       "      <td>Chlorhex Glucon_Mthwsh (Aniseed) 0.2%</td>\n",
       "      <td>1203040E0AAABAB</td>\n",
       "      <td>Chlorhexidine gluconate 0.2% mouthwash</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17748</th>\n",
       "      <td>130201000AACPCP</td>\n",
       "      <td>Liq Paraf 50%/Emulsif 50%_Oint (Old)</td>\n",
       "      <td>130201000AADMDM</td>\n",
       "      <td>Emulsifying ointment 50% / Liquid paraffin 50% ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17750</th>\n",
       "      <td>1302010F0AAAPAP</td>\n",
       "      <td>Emulsif Oint 50%/WSP 50%_Oint</td>\n",
       "      <td>130201000AADMDM</td>\n",
       "      <td>Emulsifying ointment 50% / Liquid paraffin 50% ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17827</th>\n",
       "      <td>21220000133</td>\n",
       "      <td>Ovelle Emulsif Oint 500g (App)</td>\n",
       "      <td>1302010F0AAADAD</td>\n",
       "      <td>Emulsifying ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17828</th>\n",
       "      <td>21220000137</td>\n",
       "      <td>EmulsifEss Oint 500g</td>\n",
       "      <td>1302010F0AAADAD</td>\n",
       "      <td>Emulsifying ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17890</th>\n",
       "      <td>21220000267</td>\n",
       "      <td>AquaDerm Aq Crm 100g</td>\n",
       "      <td>130201100AAAMAM</td>\n",
       "      <td>Aqueous cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17891</th>\n",
       "      <td>21220000268</td>\n",
       "      <td>AquaDerm Aq Crm</td>\n",
       "      <td>130201100AAAMAM</td>\n",
       "      <td>Aqueous cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17943</th>\n",
       "      <td>130202000BBAZA0</td>\n",
       "      <td>Derma Shield_Skin Prote Mousse 150ml</td>\n",
       "      <td>130202000BBBAA0</td>\n",
       "      <td>Derma Shield skin protector mousse</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17945</th>\n",
       "      <td>130202000BBBGA0</td>\n",
       "      <td>Derma Shield_Skin Prote Mousse 500ml</td>\n",
       "      <td>130202000BBBAA0</td>\n",
       "      <td>Derma Shield skin protector mousse</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18226</th>\n",
       "      <td>1304000H0AACUCU</td>\n",
       "      <td>Clobet/Oxytet/Nystatin_Crm0.05%/3%(Spec)</td>\n",
       "      <td>1304000H0AACACA</td>\n",
       "      <td>Clobet 0.05%/Oxytetracycline 3% /Nystatin 100,000units/g crm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18227</th>\n",
       "      <td>1304000H0AACVCV</td>\n",
       "      <td>Clobet/Oxytet/Nystatin_Crm 0.05%/3% (DT)</td>\n",
       "      <td>1304000H0AACACA</td>\n",
       "      <td>Clobet 0.05%/Oxytetracycline 3% /Nystatin 100,000units/g crm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18302</th>\n",
       "      <td>1304000T0BBAHCD</td>\n",
       "      <td>Haelan_Tape 7.5cm x 200cm</td>\n",
       "      <td>1304000T0BBAGCC</td>\n",
       "      <td>Haelan 4micrograms/square cm tape 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18303</th>\n",
       "      <td>1304000T0BBAICE</td>\n",
       "      <td>Haelan_Tape 7.5cm x 20cm</td>\n",
       "      <td>1304000T0BBAGCC</td>\n",
       "      <td>Haelan 4micrograms/square cm tape 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18661</th>\n",
       "      <td>1305020S0AABQBQ</td>\n",
       "      <td>Salic Acid 5%/WSP_Oint</td>\n",
       "      <td>1305020S0AACZCZ</td>\n",
       "      <td>Salicylic acid 5% ointment in a base</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18662</th>\n",
       "      <td>1305020S0AACBCB</td>\n",
       "      <td>Salic Acid 5%/Emulsif_Oint</td>\n",
       "      <td>1305020S0AACZCZ</td>\n",
       "      <td>Salicylic acid 5% ointment in a base</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18873</th>\n",
       "      <td>1305020S0AABRBR</td>\n",
       "      <td>Salic Acid 20%/WSP_Oint</td>\n",
       "      <td>1307000M0AABZBZ</td>\n",
       "      <td>Salicylic acid 20% ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18874</th>\n",
       "      <td>1305020S0AACFCF</td>\n",
       "      <td>Salic Acid 20%/Emulsif_Oint</td>\n",
       "      <td>1307000M0AABZBZ</td>\n",
       "      <td>Salicylic acid 20% ointment</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19134</th>\n",
       "      <td>1310020A0AAACAC</td>\n",
       "      <td>Amorolfine HCl_Nail Lacquer Kit 5% 3ml</td>\n",
       "      <td>1310020A0AAAAAA</td>\n",
       "      <td>Amorolfine 5% medicated nail lacquer</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19135</th>\n",
       "      <td>1310020A0AAADAD</td>\n",
       "      <td>Amorolfine HCl_Nail Lacquer Kit 5%</td>\n",
       "      <td>1310020A0AAAAAA</td>\n",
       "      <td>Amorolfine 5% medicated nail lacquer</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19541</th>\n",
       "      <td>140400030AAAEAE</td>\n",
       "      <td>Hepat A_Vac 320u/ml 0.5ml Pfs</td>\n",
       "      <td>140400030AAADAD</td>\n",
       "      <td>Hepatitis A vaccine (inactivated, adsorbed) inj 0.5ml pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19542</th>\n",
       "      <td>140400030AAAFAF</td>\n",
       "      <td>Hepat A_Vac 50u/ml 0.5ml Pfs</td>\n",
       "      <td>140400030AAADAD</td>\n",
       "      <td>Hepatitis A vaccine (inactivated, adsorbed) inj 0.5ml pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19612</th>\n",
       "      <td>1404000F0BMAAAX</td>\n",
       "      <td>Repevax_Vac 0.5ml Pfs</td>\n",
       "      <td>1404000F0AAAXAX</td>\n",
       "      <td>dTAP/IPV inj 0.5ml pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19613</th>\n",
       "      <td>1404000F0BPAAAX</td>\n",
       "      <td>Boostrix-IPV_Inj 0.5ml Pfs</td>\n",
       "      <td>1404000F0AAAXAX</td>\n",
       "      <td>dTAP/IPV inj 0.5ml pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19616</th>\n",
       "      <td>1404000F0BNAAA0</td>\n",
       "      <td>Infanrix-IPV_Vac 0.5ml Pfs</td>\n",
       "      <td>1404000F0AABBBB</td>\n",
       "      <td>DTaP/IPV vacc (ads) inj 0.5ml pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19617</th>\n",
       "      <td>1404000F0BNABBB</td>\n",
       "      <td>Infanrix-IPV + Hib_Vac C/Pk Pfs + Pdr Vl</td>\n",
       "      <td>1404000F0AABBBB</td>\n",
       "      <td>DTaP/IPV vacc (ads) inj 0.5ml pfs</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19891</th>\n",
       "      <td>1502010J0AABLBL</td>\n",
       "      <td>Lido HCl_Antis Gel 2% (Liq)</td>\n",
       "      <td>1502010J0AABQBQ</td>\n",
       "      <td>Lidocaine 2% and Chlorhexidine gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19893</th>\n",
       "      <td>1502010J0AABRBR</td>\n",
       "      <td>Lido HCl 2%/Chlorhex_Gel 11ml Pfs</td>\n",
       "      <td>1502010J0AABQBQ</td>\n",
       "      <td>Lidocaine 2% and Chlorhexidine gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20585</th>\n",
       "      <td>20010000102</td>\n",
       "      <td>Absorbent Cott Wool BP 100g</td>\n",
       "      <td>20010000101</td>\n",
       "      <td>Absorbent cotton BP 1988</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20586</th>\n",
       "      <td>20010000103</td>\n",
       "      <td>Absorbent Cott Wool BP 500g</td>\n",
       "      <td>20010000101</td>\n",
       "      <td>Absorbent cotton BP 1988</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21659</th>\n",
       "      <td>20030500010</td>\n",
       "      <td>IntraSite Gel 15g Wound Dress H/Gel Ster</td>\n",
       "      <td>20030500005</td>\n",
       "      <td>IntraSite Gel dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21660</th>\n",
       "      <td>20030500015</td>\n",
       "      <td>IntraSite Gel 25g Wound Dress H/Gel Ster</td>\n",
       "      <td>20030500005</td>\n",
       "      <td>IntraSite Gel dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21680</th>\n",
       "      <td>20030500101</td>\n",
       "      <td>Iodoflex Paste 10g Wound Dress H/Gel Ster</td>\n",
       "      <td>20030500100</td>\n",
       "      <td>Iodoflex paste dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21681</th>\n",
       "      <td>20030500102</td>\n",
       "      <td>Iodoflex Paste 17g Wound Dress H/Gel Ster</td>\n",
       "      <td>20030500100</td>\n",
       "      <td>Iodoflex paste dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21687</th>\n",
       "      <td>20030500121</td>\n",
       "      <td>Cutimed Gel 15g Wound Dress H/Gel Ster</td>\n",
       "      <td>20030500120</td>\n",
       "      <td>Cutimed Gel dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21688</th>\n",
       "      <td>20030500122</td>\n",
       "      <td>Cutimed Gel 25g Wound Dress H/Gel Ster</td>\n",
       "      <td>20030500120</td>\n",
       "      <td>Cutimed Gel dressing</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22592</th>\n",
       "      <td>20031400061</td>\n",
       "      <td>Alhydran Crm 100ml Wound Dress</td>\n",
       "      <td>20031400060</td>\n",
       "      <td>Alhydran cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22593</th>\n",
       "      <td>20031400062</td>\n",
       "      <td>Alhydran Crm 250ml Wound Dress</td>\n",
       "      <td>20031400060</td>\n",
       "      <td>Alhydran cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23116</th>\n",
       "      <td>20031900046</td>\n",
       "      <td>Silgen Ag Spy 10ml Wound Dress Silver Ctd Barrier</td>\n",
       "      <td>20031900045</td>\n",
       "      <td>Silgen Ag spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23117</th>\n",
       "      <td>20031900047</td>\n",
       "      <td>Silgen Ag Spy 25ml Wound Dress Silver Ctd Barrier</td>\n",
       "      <td>20031900045</td>\n",
       "      <td>Silgen Ag spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23790</th>\n",
       "      <td>20070000110</td>\n",
       "      <td>Lint Absorbent 100g</td>\n",
       "      <td>20070000100</td>\n",
       "      <td>Absorbent lint BPC</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23791</th>\n",
       "      <td>20070000120</td>\n",
       "      <td>Lint Absorbent 500g</td>\n",
       "      <td>20070000100</td>\n",
       "      <td>Absorbent lint BPC</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23853</th>\n",
       "      <td>20090000480</td>\n",
       "      <td>Comfifast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000479</td>\n",
       "      <td>Comfifast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23854</th>\n",
       "      <td>20090000481</td>\n",
       "      <td>Comfifast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000479</td>\n",
       "      <td>Comfifast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23856</th>\n",
       "      <td>20090000483</td>\n",
       "      <td>Comfifast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000482</td>\n",
       "      <td>Comfifast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23857</th>\n",
       "      <td>20090000484</td>\n",
       "      <td>Comfifast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000482</td>\n",
       "      <td>Comfifast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23859</th>\n",
       "      <td>20090000486</td>\n",
       "      <td>Comfifast 10.75cm x 3m (Yellow)Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000485</td>\n",
       "      <td>Comfifast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23860</th>\n",
       "      <td>20090000487</td>\n",
       "      <td>Comfifast 10.75cm x 5m (Yellow)Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000485</td>\n",
       "      <td>Comfifast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23865</th>\n",
       "      <td>20090000492</td>\n",
       "      <td>Acti-Fast 2-Way Stch 5cm x 3m(Green) Stkntte Elasctd V/Tublr</td>\n",
       "      <td>20090000491</td>\n",
       "      <td>Acti-Fast 2-way stretch stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23866</th>\n",
       "      <td>20090000493</td>\n",
       "      <td>Acti-Fast 2-Way Stch 5cm x 5m(Green) Stkntte Elasctd V/Tublr</td>\n",
       "      <td>20090000491</td>\n",
       "      <td>Acti-Fast 2-way stretch stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23868</th>\n",
       "      <td>20090000495</td>\n",
       "      <td>Acti-Fast 2-Way Stch 7.5cmx3m (Blue) Stkntte Elasctd V/Tublr</td>\n",
       "      <td>20090000494</td>\n",
       "      <td>Acti-Fast 2-way stretch stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23869</th>\n",
       "      <td>20090000496</td>\n",
       "      <td>Acti-Fast 2-Way Stch 7.5cmx5m (Blue) Stkntte Elasctd V/Tublr</td>\n",
       "      <td>20090000494</td>\n",
       "      <td>Acti-Fast 2-way stretch stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23871</th>\n",
       "      <td>20090000498</td>\n",
       "      <td>Acti-Fast 2-Way Stch 10.75cmx3m(Yell)Stkntte Elasctd V/Tublr</td>\n",
       "      <td>20090000497</td>\n",
       "      <td>Acti-Fast 2-way stretch stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23872</th>\n",
       "      <td>20090000499</td>\n",
       "      <td>Acti-Fast 2-Way Stch 10.75cmx5m(Yell)Stkntte Elasctd V/Tublr</td>\n",
       "      <td>20090000497</td>\n",
       "      <td>Acti-Fast 2-way stretch stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23874</th>\n",
       "      <td>20090000502</td>\n",
       "      <td>Tubifast 2-Way Stch 5cm x 5m (Green) Stkntte Elasctd Viscose</td>\n",
       "      <td>20090000510</td>\n",
       "      <td>Tubifast 2-way stretch stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23875</th>\n",
       "      <td>20090000506</td>\n",
       "      <td>Tubifast 2-Way Stch 5cm x 3m (Green) Stkntte Elasctd Viscose</td>\n",
       "      <td>20090000510</td>\n",
       "      <td>Tubifast 2-way stretch stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23877</th>\n",
       "      <td>20090000503</td>\n",
       "      <td>Tubifast 2-Way Stch 7.5cm x 5m (Blue) Stkntte ElasctdViscose</td>\n",
       "      <td>20090000520</td>\n",
       "      <td>Tubifast 2-way stretch stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23878</th>\n",
       "      <td>20090000507</td>\n",
       "      <td>Tubifast 2-Way Stch 7.5cm x 3m (Blue) Stkntte ElasctdViscose</td>\n",
       "      <td>20090000520</td>\n",
       "      <td>Tubifast 2-way stretch stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23880</th>\n",
       "      <td>20090000504</td>\n",
       "      <td>Tubifast 2-Way Stch 10.75cm x 5m YellowStkntteElasctdViscose</td>\n",
       "      <td>20090000530</td>\n",
       "      <td>Tubifast 2-way stretch stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23881</th>\n",
       "      <td>20090000508</td>\n",
       "      <td>Tubifast 2-Way Stch 10.75cm x 3m YellowStkntteElasctdViscose</td>\n",
       "      <td>20090000530</td>\n",
       "      <td>Tubifast 2-way stretch stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23931</th>\n",
       "      <td>20090000806</td>\n",
       "      <td>Coverflex 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000805</td>\n",
       "      <td>Coverflex stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23932</th>\n",
       "      <td>20090000807</td>\n",
       "      <td>Coverflex 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000805</td>\n",
       "      <td>Coverflex stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23934</th>\n",
       "      <td>20090000811</td>\n",
       "      <td>Coverflex 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000810</td>\n",
       "      <td>Coverflex stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23935</th>\n",
       "      <td>20090000812</td>\n",
       "      <td>Coverflex 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000810</td>\n",
       "      <td>Coverflex stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23937</th>\n",
       "      <td>20090000816</td>\n",
       "      <td>Coverflex 10.75cm x 3m (Yellow)Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000815</td>\n",
       "      <td>Coverflex stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23938</th>\n",
       "      <td>20090000817</td>\n",
       "      <td>Coverflex 10.75cm x 5m (Yellow)Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000815</td>\n",
       "      <td>Coverflex stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23972</th>\n",
       "      <td>20090000906</td>\n",
       "      <td>Easifast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000905</td>\n",
       "      <td>Easifast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23973</th>\n",
       "      <td>20090000907</td>\n",
       "      <td>Easifast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000905</td>\n",
       "      <td>Easifast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23975</th>\n",
       "      <td>20090000911</td>\n",
       "      <td>Easifast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000910</td>\n",
       "      <td>Easifast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23976</th>\n",
       "      <td>20090000912</td>\n",
       "      <td>Easifast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000910</td>\n",
       "      <td>Easifast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23978</th>\n",
       "      <td>20090000916</td>\n",
       "      <td>Easifast 10.75cm x 3m(Yellow) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000915</td>\n",
       "      <td>Easifast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23979</th>\n",
       "      <td>20090000917</td>\n",
       "      <td>Easifast 10.75cm x 5m(Yellow) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000915</td>\n",
       "      <td>Easifast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23989</th>\n",
       "      <td>20090000937</td>\n",
       "      <td>CliniFast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000936</td>\n",
       "      <td>CliniFast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23990</th>\n",
       "      <td>20090000938</td>\n",
       "      <td>CliniFast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000936</td>\n",
       "      <td>CliniFast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23992</th>\n",
       "      <td>20090000940</td>\n",
       "      <td>CliniFast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000939</td>\n",
       "      <td>CliniFast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23993</th>\n",
       "      <td>20090000941</td>\n",
       "      <td>CliniFast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090000939</td>\n",
       "      <td>CliniFast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23995</th>\n",
       "      <td>20090000946</td>\n",
       "      <td>CliniFast 10.75cm x 3m (Yellow) Stkntte Elasctd ViscoseTublr</td>\n",
       "      <td>20090000945</td>\n",
       "      <td>CliniFast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23996</th>\n",
       "      <td>20090000947</td>\n",
       "      <td>CliniFast 10.75cm x 5m (Yellow) Stkntte Elasctd ViscoseTublr</td>\n",
       "      <td>20090000945</td>\n",
       "      <td>CliniFast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24069</th>\n",
       "      <td>20090001026</td>\n",
       "      <td>Comfifast MultiStretch 2-way Stch 5cmx3m (Green) Stkntte</td>\n",
       "      <td>20090001025</td>\n",
       "      <td>Comfifast MultiStretch 2-way stretch stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24070</th>\n",
       "      <td>20090001027</td>\n",
       "      <td>Comfifast MultiStretch 2-way Stch 5cmx5m (Green) Stkntte</td>\n",
       "      <td>20090001025</td>\n",
       "      <td>Comfifast MultiStretch 2-way stretch stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24072</th>\n",
       "      <td>20090001031</td>\n",
       "      <td>Comfifast MultiStretch 2-way Stch 7.5cmx3m (Blue) Stkntte</td>\n",
       "      <td>20090001030</td>\n",
       "      <td>Comfifast MultiStretch 2-way stretch stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24073</th>\n",
       "      <td>20090001032</td>\n",
       "      <td>Comfifast MultiStretch 2-way Stch 7.5cmx5m (Blue) Stkntte</td>\n",
       "      <td>20090001030</td>\n",
       "      <td>Comfifast MultiStretch 2-way stretch stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24075</th>\n",
       "      <td>20090001036</td>\n",
       "      <td>Comfifast MultiStretch 2-way Stch 10.75cmx3m (Yell) Stkntte</td>\n",
       "      <td>20090001035</td>\n",
       "      <td>Comfifast MultiStretch 2-way stretch stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24076</th>\n",
       "      <td>20090001037</td>\n",
       "      <td>Comfifast MultiStretch 2-way Stch 10.75cmx5m (Yell) Stkntte</td>\n",
       "      <td>20090001035</td>\n",
       "      <td>Comfifast MultiStretch 2-way stretch stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24177</th>\n",
       "      <td>20090001172</td>\n",
       "      <td>Fortuna Fast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001171</td>\n",
       "      <td>Fortuna Fast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24178</th>\n",
       "      <td>20090001173</td>\n",
       "      <td>Fortuna Fast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001171</td>\n",
       "      <td>Fortuna Fast stockinette 5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24180</th>\n",
       "      <td>20090001175</td>\n",
       "      <td>Fortuna Fast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001174</td>\n",
       "      <td>Fortuna Fast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24181</th>\n",
       "      <td>20090001176</td>\n",
       "      <td>Fortuna Fast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001174</td>\n",
       "      <td>Fortuna Fast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24183</th>\n",
       "      <td>20090001178</td>\n",
       "      <td>Fortuna Fast 10.75cmx3m (Yellow)Stkntte Elasctd ViscoseTublr</td>\n",
       "      <td>20090001177</td>\n",
       "      <td>Fortuna Fast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24184</th>\n",
       "      <td>20090001179</td>\n",
       "      <td>Fortuna Fast 10.75cmx5m (Yellow)Stkntte Elasctd ViscoseTublr</td>\n",
       "      <td>20090001177</td>\n",
       "      <td>Fortuna Fast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24248</th>\n",
       "      <td>20090001249</td>\n",
       "      <td>Flexifast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001248</td>\n",
       "      <td>Flexifast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24249</th>\n",
       "      <td>20090001250</td>\n",
       "      <td>Flexifast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001248</td>\n",
       "      <td>Flexifast stockinette 7.5cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24251</th>\n",
       "      <td>20090001252</td>\n",
       "      <td>Flexifast 10.75cm x 3m (Yellow)Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001251</td>\n",
       "      <td>Flexifast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24252</th>\n",
       "      <td>20090001253</td>\n",
       "      <td>Flexifast 10.75cm x 5m (Yellow)Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>20090001251</td>\n",
       "      <td>Flexifast stockinette 10.75cm</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26107</th>\n",
       "      <td>21140000013</td>\n",
       "      <td>OptiLube Ster Syrg Lubricant Gel</td>\n",
       "      <td>21140000015</td>\n",
       "      <td>OptiLube sterile lubricating jelly</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26109</th>\n",
       "      <td>21140000016</td>\n",
       "      <td>OptiLube Ster Lubri Jelly</td>\n",
       "      <td>21140000015</td>\n",
       "      <td>OptiLube sterile lubricating jelly</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26349</th>\n",
       "      <td>21200000170</td>\n",
       "      <td>Jobst FarrowWrap 4000 Sml Compress System</td>\n",
       "      <td>21200000169</td>\n",
       "      <td>Jobst FarrowWrap 4000 compression system</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26350</th>\n",
       "      <td>21200000171</td>\n",
       "      <td>Jobst FarrowWrap 4000 Med Compress System</td>\n",
       "      <td>21200000169</td>\n",
       "      <td>Jobst FarrowWrap 4000 compression system</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26473</th>\n",
       "      <td>21220000249</td>\n",
       "      <td>Elave Intensive Crm 125g</td>\n",
       "      <td>21220000248</td>\n",
       "      <td>Elave Intensive cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26474</th>\n",
       "      <td>21220000250</td>\n",
       "      <td>Elave Intensive Crm 500g</td>\n",
       "      <td>21220000248</td>\n",
       "      <td>Elave Intensive cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26486</th>\n",
       "      <td>21220000261</td>\n",
       "      <td>MyriBase Gel 500g</td>\n",
       "      <td>21220000260</td>\n",
       "      <td>MyriBase gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26487</th>\n",
       "      <td>21220000310</td>\n",
       "      <td>MyriBase Gel 500ml</td>\n",
       "      <td>21220000260</td>\n",
       "      <td>MyriBase gel</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26502</th>\n",
       "      <td>1302010U0BBAAAF</td>\n",
       "      <td>Aquadrate_Crm 10% (Drug)</td>\n",
       "      <td>21220000278</td>\n",
       "      <td>Aquadrate 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26504</th>\n",
       "      <td>21220000279</td>\n",
       "      <td>Aquadrate Crm 10% 100g (App)</td>\n",
       "      <td>21220000278</td>\n",
       "      <td>Aquadrate 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26505</th>\n",
       "      <td>1302010U0BMAAAF</td>\n",
       "      <td>Hydromol Intensive_Crm 10% (Drug)</td>\n",
       "      <td>21220000280</td>\n",
       "      <td>Hydromol Intensive 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26507</th>\n",
       "      <td>21220000281</td>\n",
       "      <td>Hydromol Intensive Crm 10% 100g (App)</td>\n",
       "      <td>21220000280</td>\n",
       "      <td>Hydromol Intensive 10% cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26535</th>\n",
       "      <td>130201000BBAFA4</td>\n",
       "      <td>Diprobase_Crm</td>\n",
       "      <td>21220000311</td>\n",
       "      <td>Diprobase cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26537</th>\n",
       "      <td>21220000313</td>\n",
       "      <td>Diprobase Crm 50g (App)</td>\n",
       "      <td>21220000311</td>\n",
       "      <td>Diprobase cream</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>30542</th>\n",
       "      <td>23150101506</td>\n",
       "      <td>Hollister_Adapt No-Sting Medical Adh Remover A/Spy 50ml</td>\n",
       "      <td>23150101504</td>\n",
       "      <td>Adapt No-Sting medical adhesive remover aerosol</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>30543</th>\n",
       "      <td>23150101507</td>\n",
       "      <td>Hollister_Adapt No-Sting Medical Adh Remover A/Spy 100ml</td>\n",
       "      <td>23150101504</td>\n",
       "      <td>Adapt No-Sting medical adhesive remover aerosol</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>34130</th>\n",
       "      <td>23452704503</td>\n",
       "      <td>Loxley_Day-Drop 30ml</td>\n",
       "      <td>23452704502</td>\n",
       "      <td>Day-drop deodorant</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>34131</th>\n",
       "      <td>23452704504</td>\n",
       "      <td>Loxley_Day-Drop 7.5ml</td>\n",
       "      <td>23452704502</td>\n",
       "      <td>Day-drop deodorant</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>35956</th>\n",
       "      <td>23800108014</td>\n",
       "      <td>Hollister_Adapt Paste 14g</td>\n",
       "      <td>23800108009</td>\n",
       "      <td>Adapt paste</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>35957</th>\n",
       "      <td>23800108015</td>\n",
       "      <td>Hollister_Adapt Paste 60g</td>\n",
       "      <td>23800108009</td>\n",
       "      <td>Adapt paste</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "              old_code  \\\n",
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       "4783   0403010B0AABHBH   \n",
       "4784   0403010B0AABIBI   \n",
       "5127   0404000L0AABKBK   \n",
       "5128   0404000L0AABLBL   \n",
       "5214   0404000R0AAADAD   \n",
       "5215   0404000R0AAAEAE   \n",
       "5871   0407020A0AABIBI   \n",
       "5872   0407020A0AABSBS   \n",
       "5878   0407020A0AABMBM   \n",
       "5879   0407020A0AABQBQ   \n",
       "5946   0407020A0BNAEBL   \n",
       "5947   0407020A0BNAFBM   \n",
       "5949   0407020A0BNACBJ   \n",
       "5950   0407020A0BNADBK   \n",
       "5952   0407020A0BNAABH   \n",
       "5953   0407020A0BNABBI   \n",
       "6501   0407042F0AAATAT   \n",
       "6502   0407042F0AAAUAU   \n",
       "6568   040801050AAAZAZ   \n",
       "6569   040801050AACACA   \n",
       "6917   0408010H0BBAHAC   \n",
       "6918   0408010H0BBAIAC   \n",
       "6939   0408010N0AAEUEU   \n",
       "6940   0408010N0AAEVEV   \n",
       "6995   0408010U0AAAAAA   \n",
       "6996   0408010U0AAAMAM   \n",
       "7350   0409020C0AAAMAM   \n",
       "7351   0409020C0AAANAN   \n",
       "7454   0410020B0AABVBV   \n",
       "7455   0410020B0AACBCB   \n",
       "8891   0601012D0AAAVAV   \n",
       "8892   0601012D0AABABA   \n",
       "10318  0702020H0AAABAB   \n",
       "10319  0702020H0AAAEAE   \n",
       "10610  0704020J0AAAIAI   \n",
       "10611  0704020J0AAAKAK   \n",
       "11831  0902012L0AABRBR   \n",
       "11832  0902012L0AADCDC   \n",
       "11836  0902012L0AABCBC   \n",
       "11837  0902012L0AADEDE   \n",
       "11966  0902021S0AADBDB   \n",
       "11967  0902021S0BDAIBD   \n",
       "12163  090401000BBJGA0   \n",
       "12164  090401000BBLKA0   \n",
       "12169  090401000BBJFA0   \n",
       "12170  090401000BBLDA0   \n",
       "12669  0904010I0AABJBJ   \n",
       "12670  0904010U0AAAAAA   \n",
       "12867  090401060AAACAC   \n",
       "12869  0904010T0AAADAD   \n",
       "13272  090402000BBCEA0   \n",
       "13273  090402000BBKLA0   \n",
       "13274  090402000BBDMA0   \n",
       "13275  090402000BBDNA0   \n",
       "13334  090402000BBMJA0   \n",
       "13335  090402000BBSKA0   \n",
       "13601  090402000BBTFA0   \n",
       "13602  090402000BBVZA0   \n",
       "13804  0905013G0AABXBX   \n",
       "13806  0905013G0AADIDI   \n",
       "13810  0905013G0AACVCV   \n",
       "13812  0905013G0AADGDG   \n",
       "13935  090504100BBBRBB   \n",
       "13936  090504100BBHDBB   \n",
       "13964  090504700BBDGBC   \n",
       "13965  090504700BBFDBC   \n",
       "13967  090504700BBDNBJ   \n",
       "13968  090504700BBDXA0   \n",
       "14279  0906031C0CHABBI   \n",
       "14280  0906031C0CJAABI   \n",
       "14368  0906040G0AACACA   \n",
       "14369  0906040G0AACECE   \n",
       "14409  0906040G0AAAUAU   \n",
       "14410  0906040G0AACMCM   \n",
       "14754  0906050P0CPADA9   \n",
       "14755  0906050P0CWAFA9   \n",
       "14765  0906050P0CWAAAF   \n",
       "14766  0906050P0CWABAF   \n",
       "15247  091101000BBPXFF   \n",
       "15248  091101000BBQPFF   \n",
       "15255  091101000BBCHFP   \n",
       "15256  091101000BBPLFP   \n",
       "15431  091200000BETEEE   \n",
       "15432  091200000BEWHEE   \n",
       "15452  091200000BEIPFE   \n",
       "15453  091200000BFSAFE   \n",
       "16272  1001030U0AABTBT   \n",
       "16273  1001030U0AABUBU   \n",
       "16416  1001050A0BFAGAB   \n",
       "16417  1001050A0BKAAAB   \n",
       "16784  1104010I0AAACAC   \n",
       "16785  1104010I0AAASAS   \n",
       "17039  1106000X0AAAAAA   \n",
       "17040  1106000X0AABGBG   \n",
       "17133  1108010C0AAAEAE   \n",
       "17134  1108010C0AAAPAP   \n",
       "17168  21300000191       \n",
       "17169  21300000309       \n",
       "17175  21300000119       \n",
       "17176  21300000159       \n",
       "17198  1108010K0AACECE   \n",
       "17199  21300000133       \n",
       "17346  1202010C0AAACAC   \n",
       "17347  1202010C0AAADAD   \n",
       "17360  1202010I0AAADAD   \n",
       "17361  1202010I0AAAGAG   \n",
       "17520  1203030A0AAAAAA   \n",
       "17521  1203030A0BJAAAA   \n",
       "17621  1203040E0AAACAC   \n",
       "17622  1203040E0AAAGAG   \n",
       "17748  130201000AACPCP   \n",
       "17750  1302010F0AAAPAP   \n",
       "17827  21220000133       \n",
       "17828  21220000137       \n",
       "17890  21220000267       \n",
       "17891  21220000268       \n",
       "17943  130202000BBAZA0   \n",
       "17945  130202000BBBGA0   \n",
       "18226  1304000H0AACUCU   \n",
       "18227  1304000H0AACVCV   \n",
       "18302  1304000T0BBAHCD   \n",
       "18303  1304000T0BBAICE   \n",
       "18661  1305020S0AABQBQ   \n",
       "18662  1305020S0AACBCB   \n",
       "18873  1305020S0AABRBR   \n",
       "18874  1305020S0AACFCF   \n",
       "19134  1310020A0AAACAC   \n",
       "19135  1310020A0AAADAD   \n",
       "19541  140400030AAAEAE   \n",
       "19542  140400030AAAFAF   \n",
       "19612  1404000F0BMAAAX   \n",
       "19613  1404000F0BPAAAX   \n",
       "19616  1404000F0BNAAA0   \n",
       "19617  1404000F0BNABBB   \n",
       "19891  1502010J0AABLBL   \n",
       "19893  1502010J0AABRBR   \n",
       "20585  20010000102       \n",
       "20586  20010000103       \n",
       "21659  20030500010       \n",
       "21660  20030500015       \n",
       "21680  20030500101       \n",
       "21681  20030500102       \n",
       "21687  20030500121       \n",
       "21688  20030500122       \n",
       "22592  20031400061       \n",
       "22593  20031400062       \n",
       "23116  20031900046       \n",
       "23117  20031900047       \n",
       "23790  20070000110       \n",
       "23791  20070000120       \n",
       "23853  20090000480       \n",
       "23854  20090000481       \n",
       "23856  20090000483       \n",
       "23857  20090000484       \n",
       "23859  20090000486       \n",
       "23860  20090000487       \n",
       "23865  20090000492       \n",
       "23866  20090000493       \n",
       "23868  20090000495       \n",
       "23869  20090000496       \n",
       "23871  20090000498       \n",
       "23872  20090000499       \n",
       "23874  20090000502       \n",
       "23875  20090000506       \n",
       "23877  20090000503       \n",
       "23878  20090000507       \n",
       "23880  20090000504       \n",
       "23881  20090000508       \n",
       "23931  20090000806       \n",
       "23932  20090000807       \n",
       "23934  20090000811       \n",
       "23935  20090000812       \n",
       "23937  20090000816       \n",
       "23938  20090000817       \n",
       "23972  20090000906       \n",
       "23973  20090000907       \n",
       "23975  20090000911       \n",
       "23976  20090000912       \n",
       "23978  20090000916       \n",
       "23979  20090000917       \n",
       "23989  20090000937       \n",
       "23990  20090000938       \n",
       "23992  20090000940       \n",
       "23993  20090000941       \n",
       "23995  20090000946       \n",
       "23996  20090000947       \n",
       "24069  20090001026       \n",
       "24070  20090001027       \n",
       "24072  20090001031       \n",
       "24073  20090001032       \n",
       "24075  20090001036       \n",
       "24076  20090001037       \n",
       "24177  20090001172       \n",
       "24178  20090001173       \n",
       "24180  20090001175       \n",
       "24181  20090001176       \n",
       "24183  20090001178       \n",
       "24184  20090001179       \n",
       "24248  20090001249       \n",
       "24249  20090001250       \n",
       "24251  20090001252       \n",
       "24252  20090001253       \n",
       "26107  21140000013       \n",
       "26109  21140000016       \n",
       "26349  21200000170       \n",
       "26350  21200000171       \n",
       "26473  21220000249       \n",
       "26474  21220000250       \n",
       "26486  21220000261       \n",
       "26487  21220000310       \n",
       "26502  1302010U0BBAAAF   \n",
       "26504  21220000279       \n",
       "26505  1302010U0BMAAAF   \n",
       "26507  21220000281       \n",
       "26535  130201000BBAFA4   \n",
       "26537  21220000313       \n",
       "30542  23150101506       \n",
       "30543  23150101507       \n",
       "34130  23452704503       \n",
       "34131  23452704504       \n",
       "35956  23800108014       \n",
       "35957  23800108015       \n",
       "\n",
       "                                                           old_name  \\\n",
       "130    Gaviscon Ex Strgh_Tab Chble 500mg (Lem)                        \n",
       "131    Gaviscon Ex Strgh_Tab Chble 500mg(P/Mint                       \n",
       "224    Atrop Sulf_Oral Susp 500mcg/5ml                                \n",
       "226    Atrop Sulf_Oral Soln 500mcg/5ml (Old)                          \n",
       "248    Glycopyrronium Brom_Oral Soln 1mg/5ml                          \n",
       "249    Glycopyrronium Brom_Oral Susp 1mg/5ml                          \n",
       "254    Glycopyrronium Brom_Oral Soln 2mg/5ml                          \n",
       "255    Glycopyrronium Brom_Oral Susp 2mg/5ml                          \n",
       "721    Ispag Husk_Gran Eff Sach 3.5g Orange S/F                       \n",
       "722    Ispag Husk_Gran Eff Sach 3.5g Lem S/F                          \n",
       "864    Macrogol_Co Oral Pdr Sach 6.9g (Plain)                         \n",
       "865    Macrogol_Co Oral Pdr Sach 6.9g (Choc)S/F                       \n",
       "1222   Furosemide_Oral Soln 5mg/5ml                                   \n",
       "1223   Furosemide_Oral Susp 5mg/5ml                                   \n",
       "1818   Captopril_Oral Soln 5mg/5ml                                    \n",
       "1819   Captopril_Oral Susp 5mg/5ml                                    \n",
       "1824   Captopril_Oral Soln 25mg/5ml                                   \n",
       "1825   Captopril_Oral Susp 25mg/5ml                                   \n",
       "1903   Lisinopril_Oral Soln 5mg/5ml                                   \n",
       "1904   Lisinopril_Oral Susp 5mg/5ml                                   \n",
       "1907   Lisinopril_Oral Soln 2.5mg/5ml                                 \n",
       "1908   Lisinopril_Oral Susp 2.5mg/5ml                                 \n",
       "1961   Ramipril_Oral Soln 5mg/5ml                                     \n",
       "1962   Ramipril_Oral Susp 5mg/5ml                                     \n",
       "2197   Nitrolingual_P/Spy 400mcg (180 D)                              \n",
       "2198   Nitrolingual_P/Spy 400mcg (75 D)                               \n",
       "2305   Amlodipine_Oral Soln 5mg/5ml                                   \n",
       "2306   Amlodipine_Oral Susp 5mg/5ml                                   \n",
       "2308   Amlodipine_Oral Susp 10mg/5ml                                  \n",
       "2309   Amlodipine_Oral Soln 10mg/5ml                                  \n",
       "2875   Dipyridamole_Oral Soln 200mg/5ml                               \n",
       "2876   Dipyridamole_Oral Susp 200mg/5ml (Old)                         \n",
       "3133   Salbutamol_Pdr For Inh 200mcg (100 D)                          \n",
       "3134   Salbutamol_Pdr For Inh 200mcg (200 D)                          \n",
       "3774   Adren_Inj 1/1000 1ml Pfs (21 Gauge)                            \n",
       "3775   Adren_Inj 1/1000 1ml Pfs (25 Gauge)                            \n",
       "4138   Melatonin_Oral Susp 5mg/5ml (Old)                              \n",
       "4139   Melatonin_Oral Susp 5mg/5ml                                    \n",
       "4162   Chloral Hydrate_Oral Soln 200mg/5ml BP                         \n",
       "4163   Chloral Hydrate_Oral Susp 200mg/5ml                            \n",
       "4567   Haloperidol_Oral Soln 1mg/5ml                                  \n",
       "4568   Haloperidol_Oral Susp 1mg/5ml                                  \n",
       "4783   Amitriptyline HCl_Oral Soln 10mg/5ml                           \n",
       "4784   Amitriptyline HCl_Oral Susp 10mg/5ml                           \n",
       "5127   Dexamfet Sulf_Oral Soln 5mg/5ml                                \n",
       "5128   Dexamfet Sulf_Oral Susp 5mg/5ml                                \n",
       "5214   Modafinil_Oral Soln 100mg/5ml                                  \n",
       "5215   Modafinil_Oral Susp 100mg/5ml (Old)                            \n",
       "5871   Fentanyl_Nsl Spy 50mcg (20D)                                   \n",
       "5872   Fentanyl_Nsl Spy 50mcg/0.1ml Ud (6D)                           \n",
       "5878   Fentanyl_Nsl Spy 200mcg (20D)                                  \n",
       "5879   Fentanyl_Nsl Spy 200mcg/0.1ml Ud (6D)                          \n",
       "5946   Instanyl_Nsl Spy 200mcg (10D)                                  \n",
       "5947   Instanyl_Nsl Spy 200mcg (20D)                                  \n",
       "5949   Instanyl_Nsl Spy 100mcg (10D)                                  \n",
       "5950   Instanyl_Nsl Spy 100mcg (20D)                                  \n",
       "5952   Instanyl_Nsl Spy 50mcg (10D)                                   \n",
       "5953   Instanyl_Nsl Spy 50mcg (20D)                                   \n",
       "6501   Clonidine HCl_Oral Soln 50mcg/5ml (DT)                         \n",
       "6502   Clonidine HCl_Oral Susp 50mcg/5ml (DT)                         \n",
       "6568   Topiramate_Oral Susp 100mg/5ml                                 \n",
       "6569   Topiramate_Oral Soln 100mg/5ml (DT Old)                        \n",
       "6917   Lamictal_Tab 25mg (Monotherapy)                                \n",
       "6918   Lamictal_Tab 25mg (Valpr)                                      \n",
       "6939   Phenobarb_Oral Soln 50mg/5ml                                   \n",
       "6940   Phenobarb_Oral Susp 50mg/5ml                                   \n",
       "6995   Primidone_Oral Susp 250mg/5ml (Old)                            \n",
       "6996   Primidone_Oral Susp 250mg/5ml (Spec)                           \n",
       "7350   Trihexyphenidyl HCl_Oral Soln 2mg/5ml                          \n",
       "7351   Trihexyphenidyl HCl_Oral Susp 2mg/5ml                          \n",
       "7454   Nicotine_Loz 1.5mg S/F (Cherry)                                \n",
       "7455   Nicotine_Loz 1.5mg S/F (Orange)                                \n",
       "8891   Gppe Ins_Humulin M3 Humaject 3ml Pf Pen                        \n",
       "8892   Ins Bip Isophane_30/70 100u/ml 3ml Cart                        \n",
       "10318  Econazole Nit_Pess 150mg + Applic                              \n",
       "10319  Econazole Nit_Pess 150mg + Applic                              \n",
       "10610  Oxybutynin HCl_Oral Soln 2.5mg/5ml (Old)                       \n",
       "10611  Oxybutynin HCl_Oral Susp 2.5mg/5ml                             \n",
       "11831  Sod Chlor_Liq Spec 292.5mg/5ml                                 \n",
       "11832  Sod Chlor_Oral Soln 292.5mg/5ml S/F                            \n",
       "11836  Sod Chlor_Liq Spec 1.46g/5ml                                   \n",
       "11837  Sod Chlor_Oral Soln 1.46g/5ml (DT Old)                         \n",
       "11966  Glucose/Sod Chlor_I/V Inf5%/0.9%500ml@gn                       \n",
       "11967  Steriflex_No3 Gluc5%/SodChlor.9%Inf500ml                       \n",
       "12163  Calogen_Emuls (Sbery)                                          \n",
       "12164  Calogen_Emuls (Banana)                                         \n",
       "12169  Neocate Advance_Pdr Sach 100g (Unflav)                         \n",
       "12170  Neocate Advance_Pdr Sach 50g (Flav)                            \n",
       "12669  G/F_Bisc                                                       \n",
       "12670  G/F /W/F_Bread                                                 \n",
       "12867  G/F /L/P_Meals                                                 \n",
       "12869  G/F /L/P_Pasta                                                 \n",
       "13272  Peptamen_Liq Diet (Vanilla)                                    \n",
       "13273  Peptamen_Dripac-Flex Liq (Unflav)                              \n",
       "13274  Seravit_Paed Mix Unflav                                        \n",
       "13275  Seravit_Paed Mix P/Apple                                       \n",
       "13334  Optifibre_Pdr Sach 8g                                          \n",
       "13335  Optifibre_Pdr Sach 10g                                         \n",
       "13601  Pro-Cal_Shot S/Pack 750ml                                      \n",
       "13602  Pro-Cal_Shot S/Pack 240ml                                      \n",
       "13804  Mag Glycerophos_Oral Soln97.2mg/5ml(Old)                       \n",
       "13806  Mag Glycerophos_Oral Soln 97.2mg/5ml                           \n",
       "13810  Mag Glycerophos_OralSoln121.25mg/5ml Old                       \n",
       "13812  Mag Glycerophos_OralSoln121.25mg/5mlSpec                       \n",
       "13935  Lamb_Zn (Cit) Cap 50mg (8283)                                  \n",
       "13936  Vega_Zn Cit V/Cap 50mg                                         \n",
       "13964  Solgar_Selenium Tab 200mcg                                     \n",
       "13965  HealthAid_Selenium Tab 200mcg                                  \n",
       "13967  Solgar_Selenium Tab 100mcg                                     \n",
       "13968  Cytoplan_Selenium Tab 100mcg                                   \n",
       "14279  BioCare_Vit C Cap 500mg                                        \n",
       "14280  Solgar_Vit C V/Cap 500mg                                       \n",
       "14368  Colecal & Calc_Tab Chble 400u/1.5g (Lem)                       \n",
       "14369  Colecal & Calc_Tab Chble 400u/1.5g                             \n",
       "14409  Colecal_Oral Susp 15,000u/5ml                                  \n",
       "14410  Colecal_Oral Soln 15,000u/5ml (Old)                            \n",
       "14754  Natures Aid_Natur Vit ESoftgelsCap1,000u                       \n",
       "14755  Solgar_Vit E Cap 1,000u                                        \n",
       "14765  Solgar_Vit E Mixed Soft Gel 400u (268mg)                       \n",
       "14766  Solgar_Vit E Dry V/Cap 400u (268mg)                            \n",
       "15247  Quest_L-Glutamine Cap 500mg                                    \n",
       "15248  Solgar_L-Glutamine V/Cap 500mg                                 \n",
       "15255  Lamb_L-Phenylalanine Cap 500mg (8321)                          \n",
       "15256  Quest_L-Phenylalanine Cap 500mg                                \n",
       "15431  NatraHealth_Glucosam+Chond Cap 400/100mg                       \n",
       "15432  BR Pharm_Glucosamine + Chondroitin Cap                         \n",
       "15452  HealthAid_MSM Tab 1g                                           \n",
       "15453  H/Nature_MSM Tab 1000mg                                        \n",
       "16272  Methotrexate_Oral Soln 10mg/5ml                                \n",
       "16273  Methotrexate_Oral Susp 10mg/5ml                                \n",
       "16416  Natures Aid_Veget Glucosam HCl Tab 750mg                       \n",
       "16417  Health+Plus_Glucosamine HCl Tab 750mg                          \n",
       "16784  Dexameth_Eye Dps 0.1% P/F (Old)                                \n",
       "16785  Dexameth_Eye Dps 0.1% P/F (DT Old)                             \n",
       "17039  Piloc HCl_Eye Dps 0.5% (DT Old)                                \n",
       "17040  Piloc HCl_Eye Dps 0.5% P/F                                     \n",
       "17133  Acetylcy_Eye Dps 10%                                           \n",
       "17134  Acetylcy_Eye Dps 10% P/F (DT Old)                              \n",
       "17168  Sai-Meds Hypromellose 0.5% Eye Dps 10ml                        \n",
       "17169  Teardew 0.5% Hypromellose Eye Dps 10ml                         \n",
       "17175  Tear-Lac Hypromellose Eye Dps 0.3% P/F                         \n",
       "17176  PF Drops Hypromellose 0.3% Eye Dps 10ml P/F                    \n",
       "17198  Sod Chlor_Eye Dps 5% P/F                                       \n",
       "17199  PF Drops Sod Chlor 5% Eye Dps 10ml P/F                         \n",
       "17346  Beclomet Diprop_Aq Nsl Spy 50mcg (100 D)                       \n",
       "17347  Beclomet Diprop_Nsl Spy 50mcg (180 D)                          \n",
       "17360  Budesonide_Aq Nsl Spy 100mcg (200D)                            \n",
       "17361  Budesonide_Aq Nsl Spy 100mcg (150D)                            \n",
       "17520  Dichlor Alc/Amylmet_Loz 1.2mg/600mcg                           \n",
       "17521  Throaties_A-Bact Pastil(R/Currant&R/Hip)                       \n",
       "17621  Chlorhex Glucon_Mthwsh (Mint) 0.2%                             \n",
       "17622  Chlorhex Glucon_Mthwsh (Aniseed) 0.2%                          \n",
       "17748  Liq Paraf 50%/Emulsif 50%_Oint (Old)                           \n",
       "17750  Emulsif Oint 50%/WSP 50%_Oint                                  \n",
       "17827  Ovelle Emulsif Oint 500g (App)                                 \n",
       "17828  EmulsifEss Oint 500g                                           \n",
       "17890  AquaDerm Aq Crm 100g                                           \n",
       "17891  AquaDerm Aq Crm                                                \n",
       "17943  Derma Shield_Skin Prote Mousse 150ml                           \n",
       "17945  Derma Shield_Skin Prote Mousse 500ml                           \n",
       "18226  Clobet/Oxytet/Nystatin_Crm0.05%/3%(Spec)                       \n",
       "18227  Clobet/Oxytet/Nystatin_Crm 0.05%/3% (DT)                       \n",
       "18302  Haelan_Tape 7.5cm x 200cm                                      \n",
       "18303  Haelan_Tape 7.5cm x 20cm                                       \n",
       "18661  Salic Acid 5%/WSP_Oint                                         \n",
       "18662  Salic Acid 5%/Emulsif_Oint                                     \n",
       "18873  Salic Acid 20%/WSP_Oint                                        \n",
       "18874  Salic Acid 20%/Emulsif_Oint                                    \n",
       "19134  Amorolfine HCl_Nail Lacquer Kit 5% 3ml                         \n",
       "19135  Amorolfine HCl_Nail Lacquer Kit 5%                             \n",
       "19541  Hepat A_Vac 320u/ml 0.5ml Pfs                                  \n",
       "19542  Hepat A_Vac 50u/ml 0.5ml Pfs                                   \n",
       "19612  Repevax_Vac 0.5ml Pfs                                          \n",
       "19613  Boostrix-IPV_Inj 0.5ml Pfs                                     \n",
       "19616  Infanrix-IPV_Vac 0.5ml Pfs                                     \n",
       "19617  Infanrix-IPV + Hib_Vac C/Pk Pfs + Pdr Vl                       \n",
       "19891  Lido HCl_Antis Gel 2% (Liq)                                    \n",
       "19893  Lido HCl 2%/Chlorhex_Gel 11ml Pfs                              \n",
       "20585  Absorbent Cott Wool BP 100g                                    \n",
       "20586  Absorbent Cott Wool BP 500g                                    \n",
       "21659  IntraSite Gel 15g Wound Dress H/Gel Ster                       \n",
       "21660  IntraSite Gel 25g Wound Dress H/Gel Ster                       \n",
       "21680  Iodoflex Paste 10g Wound Dress H/Gel Ster                      \n",
       "21681  Iodoflex Paste 17g Wound Dress H/Gel Ster                      \n",
       "21687  Cutimed Gel 15g Wound Dress H/Gel Ster                         \n",
       "21688  Cutimed Gel 25g Wound Dress H/Gel Ster                         \n",
       "22592  Alhydran Crm 100ml Wound Dress                                 \n",
       "22593  Alhydran Crm 250ml Wound Dress                                 \n",
       "23116  Silgen Ag Spy 10ml Wound Dress Silver Ctd Barrier              \n",
       "23117  Silgen Ag Spy 25ml Wound Dress Silver Ctd Barrier              \n",
       "23790  Lint Absorbent 100g                                            \n",
       "23791  Lint Absorbent 500g                                            \n",
       "23853  Comfifast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr       \n",
       "23854  Comfifast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr       \n",
       "23856  Comfifast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "23857  Comfifast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "23859  Comfifast 10.75cm x 3m (Yellow)Stkntte Elasctd Viscose Tublr   \n",
       "23860  Comfifast 10.75cm x 5m (Yellow)Stkntte Elasctd Viscose Tublr   \n",
       "23865  Acti-Fast 2-Way Stch 5cm x 3m(Green) Stkntte Elasctd V/Tublr   \n",
       "23866  Acti-Fast 2-Way Stch 5cm x 5m(Green) Stkntte Elasctd V/Tublr   \n",
       "23868  Acti-Fast 2-Way Stch 7.5cmx3m (Blue) Stkntte Elasctd V/Tublr   \n",
       "23869  Acti-Fast 2-Way Stch 7.5cmx5m (Blue) Stkntte Elasctd V/Tublr   \n",
       "23871  Acti-Fast 2-Way Stch 10.75cmx3m(Yell)Stkntte Elasctd V/Tublr   \n",
       "23872  Acti-Fast 2-Way Stch 10.75cmx5m(Yell)Stkntte Elasctd V/Tublr   \n",
       "23874  Tubifast 2-Way Stch 5cm x 5m (Green) Stkntte Elasctd Viscose   \n",
       "23875  Tubifast 2-Way Stch 5cm x 3m (Green) Stkntte Elasctd Viscose   \n",
       "23877  Tubifast 2-Way Stch 7.5cm x 5m (Blue) Stkntte ElasctdViscose   \n",
       "23878  Tubifast 2-Way Stch 7.5cm x 3m (Blue) Stkntte ElasctdViscose   \n",
       "23880  Tubifast 2-Way Stch 10.75cm x 5m YellowStkntteElasctdViscose   \n",
       "23881  Tubifast 2-Way Stch 10.75cm x 3m YellowStkntteElasctdViscose   \n",
       "23931  Coverflex 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr       \n",
       "23932  Coverflex 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr       \n",
       "23934  Coverflex 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "23935  Coverflex 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "23937  Coverflex 10.75cm x 3m (Yellow)Stkntte Elasctd Viscose Tublr   \n",
       "23938  Coverflex 10.75cm x 5m (Yellow)Stkntte Elasctd Viscose Tublr   \n",
       "23972  Easifast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr        \n",
       "23973  Easifast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr        \n",
       "23975  Easifast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr       \n",
       "23976  Easifast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr       \n",
       "23978  Easifast 10.75cm x 3m(Yellow) Stkntte Elasctd Viscose Tublr    \n",
       "23979  Easifast 10.75cm x 5m(Yellow) Stkntte Elasctd Viscose Tublr    \n",
       "23989  CliniFast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr       \n",
       "23990  CliniFast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr       \n",
       "23992  CliniFast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "23993  CliniFast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "23995  CliniFast 10.75cm x 3m (Yellow) Stkntte Elasctd ViscoseTublr   \n",
       "23996  CliniFast 10.75cm x 5m (Yellow) Stkntte Elasctd ViscoseTublr   \n",
       "24069  Comfifast MultiStretch 2-way Stch 5cmx3m (Green) Stkntte       \n",
       "24070  Comfifast MultiStretch 2-way Stch 5cmx5m (Green) Stkntte       \n",
       "24072  Comfifast MultiStretch 2-way Stch 7.5cmx3m (Blue) Stkntte      \n",
       "24073  Comfifast MultiStretch 2-way Stch 7.5cmx5m (Blue) Stkntte      \n",
       "24075  Comfifast MultiStretch 2-way Stch 10.75cmx3m (Yell) Stkntte    \n",
       "24076  Comfifast MultiStretch 2-way Stch 10.75cmx5m (Yell) Stkntte    \n",
       "24177  Fortuna Fast 5cm x 3m (Green) Stkntte Elasctd Viscose Tublr    \n",
       "24178  Fortuna Fast 5cm x 5m (Green) Stkntte Elasctd Viscose Tublr    \n",
       "24180  Fortuna Fast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr   \n",
       "24181  Fortuna Fast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr   \n",
       "24183  Fortuna Fast 10.75cmx3m (Yellow)Stkntte Elasctd ViscoseTublr   \n",
       "24184  Fortuna Fast 10.75cmx5m (Yellow)Stkntte Elasctd ViscoseTublr   \n",
       "24248  Flexifast 7.5cm x 3m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "24249  Flexifast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr      \n",
       "24251  Flexifast 10.75cm x 3m (Yellow)Stkntte Elasctd Viscose Tublr   \n",
       "24252  Flexifast 10.75cm x 5m (Yellow)Stkntte Elasctd Viscose Tublr   \n",
       "26107  OptiLube Ster Syrg Lubricant Gel                               \n",
       "26109  OptiLube Ster Lubri Jelly                                      \n",
       "26349  Jobst FarrowWrap 4000 Sml Compress System                      \n",
       "26350  Jobst FarrowWrap 4000 Med Compress System                      \n",
       "26473  Elave Intensive Crm 125g                                       \n",
       "26474  Elave Intensive Crm 500g                                       \n",
       "26486  MyriBase Gel 500g                                              \n",
       "26487  MyriBase Gel 500ml                                             \n",
       "26502  Aquadrate_Crm 10% (Drug)                                       \n",
       "26504  Aquadrate Crm 10% 100g (App)                                   \n",
       "26505  Hydromol Intensive_Crm 10% (Drug)                              \n",
       "26507  Hydromol Intensive Crm 10% 100g (App)                          \n",
       "26535  Diprobase_Crm                                                  \n",
       "26537  Diprobase Crm 50g (App)                                        \n",
       "30542  Hollister_Adapt No-Sting Medical Adh Remover A/Spy 50ml        \n",
       "30543  Hollister_Adapt No-Sting Medical Adh Remover A/Spy 100ml       \n",
       "34130  Loxley_Day-Drop 30ml                                           \n",
       "34131  Loxley_Day-Drop 7.5ml                                          \n",
       "35956  Hollister_Adapt Paste 14g                                      \n",
       "35957  Hollister_Adapt Paste 60g                                      \n",
       "\n",
       "              new_code  \\\n",
       "130    0101021B0AAAGAG   \n",
       "131    0101021B0AAAGAG   \n",
       "224    0102000ACAABABA   \n",
       "226    0102000ACAABABA   \n",
       "248    0102000L0AAADAD   \n",
       "249    0102000L0AAADAD   \n",
       "254    0102000L0AAAIAI   \n",
       "255    0102000L0AAAIAI   \n",
       "721    0106010E0AAADAD   \n",
       "722    0106010E0AAADAD   \n",
       "864    0106040M0AAABAB   \n",
       "865    0106040M0AAABAB   \n",
       "1222   0202020L0AACACA   \n",
       "1223   0202020L0AACACA   \n",
       "1818   0205051F0AABNBN   \n",
       "1819   0205051F0AABNBN   \n",
       "1824   0205051F0AABWBW   \n",
       "1825   0205051F0AABWBW   \n",
       "1903   0205051L0AAAGAG   \n",
       "1904   0205051L0AAAGAG   \n",
       "1907   0205051L0AAAIAI   \n",
       "1908   0205051L0AAAIAI   \n",
       "1961   0205051R0AAAEAE   \n",
       "1962   0205051R0AAAEAE   \n",
       "2197   0206010F0BFABCJ   \n",
       "2198   0206010F0BFABCJ   \n",
       "2305   0206020A0AAACAC   \n",
       "2306   0206020A0AAACAC   \n",
       "2308   0206020A0AAADAD   \n",
       "2309   0206020A0AAADAD   \n",
       "2875   0209000L0AAAZAZ   \n",
       "2876   0209000L0AAAZAZ   \n",
       "3133   0301011R0AAAQAQ   \n",
       "3134   0301011R0AAAQAQ   \n",
       "3774   0304030C0AAAYAY   \n",
       "3775   0304030C0AAAYAY   \n",
       "4138   0401010ADAADEDE   \n",
       "4139   0401010ADAADEDE   \n",
       "4162   0401010B0AABGBG   \n",
       "4163   0401010B0AABGBG   \n",
       "4567   0402010J0AAA7A7   \n",
       "4568   0402010J0AAA7A7   \n",
       "4783   0403010B0AAA6A6   \n",
       "4784   0403010B0AAA6A6   \n",
       "5127   0404000L0AAAMAM   \n",
       "5128   0404000L0AAAMAM   \n",
       "5214   0404000R0AAAGAG   \n",
       "5215   0404000R0AAAGAG   \n",
       "5871   0407020A0AABHBH   \n",
       "5872   0407020A0AABHBH   \n",
       "5878   0407020A0AABLBL   \n",
       "5879   0407020A0AABLBL   \n",
       "5946   0407020A0BNAGBQ   \n",
       "5947   0407020A0BNAGBQ   \n",
       "5949   0407020A0BNAHBR   \n",
       "5950   0407020A0BNAHBR   \n",
       "5952   0407020A0BNAIBS   \n",
       "5953   0407020A0BNAIBS   \n",
       "6501   0407042F0AAAFAF   \n",
       "6502   0407042F0AAAFAF   \n",
       "6568   040801050AACCCC   \n",
       "6569   040801050AACCCC   \n",
       "6917   0408010H0BBACAC   \n",
       "6918   0408010H0BBACAC   \n",
       "6939   0408010N0AACLCL   \n",
       "6940   0408010N0AACLCL   \n",
       "6995   0408010U0AABCBC   \n",
       "6996   0408010U0AABCBC   \n",
       "7350   0409020C0AAALAL   \n",
       "7351   0409020C0AAALAL   \n",
       "7454   0410020B0AABPBP   \n",
       "7455   0410020B0AABPBP   \n",
       "8891   0601012D0AABZBZ   \n",
       "8892   0601012D0AABZBZ   \n",
       "10318  0702020H0AAAFAF   \n",
       "10319  0702020H0AAAFAF   \n",
       "10610  0704020J0AAAZAZ   \n",
       "10611  0704020J0AAAZAZ   \n",
       "11831  0902012L0AADDDD   \n",
       "11832  0902012L0AADDDD   \n",
       "11836  0902012L0AADHDH   \n",
       "11837  0902012L0AADHDH   \n",
       "11966  0902021S0AABDBD   \n",
       "11967  0902021S0AABDBD   \n",
       "12163  090401000AABABA   \n",
       "12164  090401000AABABA   \n",
       "12169  090401000AACHCH   \n",
       "12170  090401000AACHCH   \n",
       "12669  0904010A0AABFBF   \n",
       "12670  0904010A0AABFBF   \n",
       "12867  0904010AQAAAAAA   \n",
       "12869  0904010AQAAAAAA   \n",
       "13272  090402000AAASAS   \n",
       "13273  090402000AAASAS   \n",
       "13274  090402000AAATAT   \n",
       "13275  090402000AAATAT   \n",
       "13334  090402000BBHWA0   \n",
       "13335  090402000BBHWA0   \n",
       "13601  090402000BBWUA0   \n",
       "13602  090402000BBWUA0   \n",
       "13804  0905013G0AADCDC   \n",
       "13806  0905013G0AADCDC   \n",
       "13810  0905013G0AADFDF   \n",
       "13812  0905013G0AADFDF   \n",
       "13935  090504100AABBBB   \n",
       "13936  090504100AABBBB   \n",
       "13964  090504700AABCBC   \n",
       "13965  090504700AABCBC   \n",
       "13967  090504700AABJBJ   \n",
       "13968  090504700AABJBJ   \n",
       "14279  0906031C0AABIBI   \n",
       "14280  0906031C0AABIBI   \n",
       "14368  0906040G0AABYBY   \n",
       "14369  0906040G0AABYBY   \n",
       "14409  0906040G0AADSDS   \n",
       "14410  0906040G0AADSDS   \n",
       "14754  0906050P0AAA9A9   \n",
       "14755  0906050P0AAA9A9   \n",
       "14765  0906050P0AAAFAF   \n",
       "14766  0906050P0AAAFAF   \n",
       "15247  091101000AAFFFF   \n",
       "15248  091101000AAFFFF   \n",
       "15255  091101000AAFPFP   \n",
       "15256  091101000AAFPFP   \n",
       "15431  091200000AAEEEE   \n",
       "15432  091200000AAEEEE   \n",
       "15452  091200000AAFEFE   \n",
       "15453  091200000AAFEFE   \n",
       "16272  1001030U0AAAHAH   \n",
       "16273  1001030U0AAAHAH   \n",
       "16416  1001050A0AAABAB   \n",
       "16417  1001050A0AAABAB   \n",
       "16784  1104010I0AAAUAU   \n",
       "16785  1104010I0AAAUAU   \n",
       "17039  1106000X0AABPBP   \n",
       "17040  1106000X0AABPBP   \n",
       "17133  1108010C0AABABA   \n",
       "17134  1108010C0AABABA   \n",
       "17168  1108010F0AAABAB   \n",
       "17169  1108010F0AAABAB   \n",
       "17175  1108010F0AAANAN   \n",
       "17176  1108010F0AAANAN   \n",
       "17198  1108010K0AAA6A6   \n",
       "17199  1108010K0AAA6A6   \n",
       "17346  1202010C0AAAAAA   \n",
       "17347  1202010C0AAAAAA   \n",
       "17360  1202010I0AAACAC   \n",
       "17361  1202010I0AAACAC   \n",
       "17520  1203030A0AAAEAE   \n",
       "17521  1203030A0AAAEAE   \n",
       "17621  1203040E0AAABAB   \n",
       "17622  1203040E0AAABAB   \n",
       "17748  130201000AADMDM   \n",
       "17750  130201000AADMDM   \n",
       "17827  1302010F0AAADAD   \n",
       "17828  1302010F0AAADAD   \n",
       "17890  130201100AAAMAM   \n",
       "17891  130201100AAAMAM   \n",
       "17943  130202000BBBAA0   \n",
       "17945  130202000BBBAA0   \n",
       "18226  1304000H0AACACA   \n",
       "18227  1304000H0AACACA   \n",
       "18302  1304000T0BBAGCC   \n",
       "18303  1304000T0BBAGCC   \n",
       "18661  1305020S0AACZCZ   \n",
       "18662  1305020S0AACZCZ   \n",
       "18873  1307000M0AABZBZ   \n",
       "18874  1307000M0AABZBZ   \n",
       "19134  1310020A0AAAAAA   \n",
       "19135  1310020A0AAAAAA   \n",
       "19541  140400030AAADAD   \n",
       "19542  140400030AAADAD   \n",
       "19612  1404000F0AAAXAX   \n",
       "19613  1404000F0AAAXAX   \n",
       "19616  1404000F0AABBBB   \n",
       "19617  1404000F0AABBBB   \n",
       "19891  1502010J0AABQBQ   \n",
       "19893  1502010J0AABQBQ   \n",
       "20585  20010000101       \n",
       "20586  20010000101       \n",
       "21659  20030500005       \n",
       "21660  20030500005       \n",
       "21680  20030500100       \n",
       "21681  20030500100       \n",
       "21687  20030500120       \n",
       "21688  20030500120       \n",
       "22592  20031400060       \n",
       "22593  20031400060       \n",
       "23116  20031900045       \n",
       "23117  20031900045       \n",
       "23790  20070000100       \n",
       "23791  20070000100       \n",
       "23853  20090000479       \n",
       "23854  20090000479       \n",
       "23856  20090000482       \n",
       "23857  20090000482       \n",
       "23859  20090000485       \n",
       "23860  20090000485       \n",
       "23865  20090000491       \n",
       "23866  20090000491       \n",
       "23868  20090000494       \n",
       "23869  20090000494       \n",
       "23871  20090000497       \n",
       "23872  20090000497       \n",
       "23874  20090000510       \n",
       "23875  20090000510       \n",
       "23877  20090000520       \n",
       "23878  20090000520       \n",
       "23880  20090000530       \n",
       "23881  20090000530       \n",
       "23931  20090000805       \n",
       "23932  20090000805       \n",
       "23934  20090000810       \n",
       "23935  20090000810       \n",
       "23937  20090000815       \n",
       "23938  20090000815       \n",
       "23972  20090000905       \n",
       "23973  20090000905       \n",
       "23975  20090000910       \n",
       "23976  20090000910       \n",
       "23978  20090000915       \n",
       "23979  20090000915       \n",
       "23989  20090000936       \n",
       "23990  20090000936       \n",
       "23992  20090000939       \n",
       "23993  20090000939       \n",
       "23995  20090000945       \n",
       "23996  20090000945       \n",
       "24069  20090001025       \n",
       "24070  20090001025       \n",
       "24072  20090001030       \n",
       "24073  20090001030       \n",
       "24075  20090001035       \n",
       "24076  20090001035       \n",
       "24177  20090001171       \n",
       "24178  20090001171       \n",
       "24180  20090001174       \n",
       "24181  20090001174       \n",
       "24183  20090001177       \n",
       "24184  20090001177       \n",
       "24248  20090001248       \n",
       "24249  20090001248       \n",
       "24251  20090001251       \n",
       "24252  20090001251       \n",
       "26107  21140000015       \n",
       "26109  21140000015       \n",
       "26349  21200000169       \n",
       "26350  21200000169       \n",
       "26473  21220000248       \n",
       "26474  21220000248       \n",
       "26486  21220000260       \n",
       "26487  21220000260       \n",
       "26502  21220000278       \n",
       "26504  21220000278       \n",
       "26505  21220000280       \n",
       "26507  21220000280       \n",
       "26535  21220000311       \n",
       "26537  21220000311       \n",
       "30542  23150101504       \n",
       "30543  23150101504       \n",
       "34130  23452704502       \n",
       "34131  23452704502       \n",
       "35956  23800108009       \n",
       "35957  23800108009       \n",
       "\n",
       "                                                           new_name changed  \n",
       "130    Generic Gaviscon 500mg chewable tablets sugar free            Y       \n",
       "131    Generic Gaviscon 500mg chewable tablets sugar free            Y       \n",
       "224    Atropine 500micrograms/5ml oral solution                      Y       \n",
       "226    Atropine 500micrograms/5ml oral solution                      Y       \n",
       "248    Glycopyrronium bromide 1mg/5ml oral liquid                    Y       \n",
       "249    Glycopyrronium bromide 1mg/5ml oral liquid                    Y       \n",
       "254    Glycopyrronium bromide 2mg/5ml oral liquid                    Y       \n",
       "255    Glycopyrronium bromide 2mg/5ml oral liquid                    Y       \n",
       "721    Ispaghula husk 3.5g efferv gran sach gluten free sugar free   Y       \n",
       "722    Ispaghula husk 3.5g efferv gran sach gluten free sugar free   Y       \n",
       "864    Macrogol compound half-strength oral pdr sach NPF sugar free  Y       \n",
       "865    Macrogol compound half-strength oral pdr sach NPF sugar free  Y       \n",
       "1222   Furosemide 5mg/5ml oral liquid                                Y       \n",
       "1223   Furosemide 5mg/5ml oral liquid                                Y       \n",
       "1818   Captopril 5mg/5ml oral liquid                                 Y       \n",
       "1819   Captopril 5mg/5ml oral liquid                                 Y       \n",
       "1824   Captopril 25mg/5ml oral liquid                                Y       \n",
       "1825   Captopril 25mg/5ml oral liquid                                Y       \n",
       "1903   Lisinopril 5mg/5ml oral liquid                                Y       \n",
       "1904   Lisinopril 5mg/5ml oral liquid                                Y       \n",
       "1907   Lisinopril 2.5mg/5ml oral liquid                              Y       \n",
       "1908   Lisinopril 2.5mg/5ml oral liquid                              Y       \n",
       "1961   Ramipril 5mg/5ml oral liquid                                  Y       \n",
       "1962   Ramipril 5mg/5ml oral liquid                                  Y       \n",
       "2197   Nitrolingual 400micrograms/dose pump sublingual spray         Y       \n",
       "2198   Nitrolingual 400micrograms/dose pump sublingual spray         Y       \n",
       "2305   Amlodipine 5mg/5ml oral liquid                                Y       \n",
       "2306   Amlodipine 5mg/5ml oral liquid                                Y       \n",
       "2308   Amlodipine 10mg/5ml oral liquid                               Y       \n",
       "2309   Amlodipine 10mg/5ml oral liquid                               Y       \n",
       "2875   Dipyridamole 200mg/5ml oral suspension                        Y       \n",
       "2876   Dipyridamole 200mg/5ml oral suspension                        Y       \n",
       "3133   Salbutamol 200micrograms/dose dry powder inhaler              Y       \n",
       "3134   Salbutamol 200micrograms/dose dry powder inhaler              Y       \n",
       "3774   Adrenaline (base) 1mg/1ml (1 in 1,000) inj pfs                Y       \n",
       "3775   Adrenaline (base) 1mg/1ml (1 in 1,000) inj pfs                Y       \n",
       "4138   Melatonin 5mg/5ml oral suspension                             Y       \n",
       "4139   Melatonin 5mg/5ml oral suspension                             Y       \n",
       "4162   Chloral hydrate 200mg/5ml oral liquid                         Y       \n",
       "4163   Chloral hydrate 200mg/5ml oral liquid                         Y       \n",
       "4567   Haloperidol 1mg/5ml oral liquid                               Y       \n",
       "4568   Haloperidol 1mg/5ml oral liquid                               Y       \n",
       "4783   Amitriptyline 10mg/5ml oral liquid                            Y       \n",
       "4784   Amitriptyline 10mg/5ml oral liquid                            Y       \n",
       "5127   Dexamfetamine 5mg/5ml oral liquid                             Y       \n",
       "5128   Dexamfetamine 5mg/5ml oral liquid                             Y       \n",
       "5214   Modafinil 100mg/5ml oral suspension                           Y       \n",
       "5215   Modafinil 100mg/5ml oral suspension                           Y       \n",
       "5871   Fentanyl 50micrograms/dose nasal spray                        Y       \n",
       "5872   Fentanyl 50micrograms/dose nasal spray                        Y       \n",
       "5878   Fentanyl 200micrograms/dose nasal spray                       Y       \n",
       "5879   Fentanyl 200micrograms/dose nasal spray                       Y       \n",
       "5946   Instanyl 200micrograms/dose nasal spray                       Y       \n",
       "5947   Instanyl 200micrograms/dose nasal spray                       Y       \n",
       "5949   Instanyl 100micrograms/dose nasal spray                       Y       \n",
       "5950   Instanyl 100micrograms/dose nasal spray                       Y       \n",
       "5952   Instanyl 50micrograms/dose nasal spray                        Y       \n",
       "5953   Instanyl 50micrograms/dose nasal spray                        Y       \n",
       "6501   Clonidine 50micrograms/5ml oral liquid                        Y       \n",
       "6502   Clonidine 50micrograms/5ml oral liquid                        Y       \n",
       "6568   Topiramate 100mg/5ml oral solution                            Y       \n",
       "6569   Topiramate 100mg/5ml oral solution                            Y       \n",
       "6917   Lamictal 25mg tablets                                         Y       \n",
       "6918   Lamictal 25mg tablets                                         Y       \n",
       "6939   Phenobarbital 50mg/5ml oral liquid                            Y       \n",
       "6940   Phenobarbital 50mg/5ml oral liquid                            Y       \n",
       "6995   Primidone 250mg/5ml oral suspension                           Y       \n",
       "6996   Primidone 250mg/5ml oral suspension                           Y       \n",
       "7350   Trihexyphenidyl 2mg/5ml oral liquid                           Y       \n",
       "7351   Trihexyphenidyl 2mg/5ml oral liquid                           Y       \n",
       "7454   Nicotine 1.5mg lozenges sugar free                            Y       \n",
       "7455   Nicotine 1.5mg lozenges sugar free                            Y       \n",
       "8891   Insulin isoph biphas hum 30/70 100u/ml inj 3ml pf dispos dev  Y       \n",
       "8892   Insulin isoph biphas hum 30/70 100u/ml inj 3ml pf dispos dev  Y       \n",
       "10318  Econazole 150mg pessaries                                     Y       \n",
       "10319  Econazole 150mg pessaries                                     Y       \n",
       "10610  Oxybutynin 2.5mg/5ml oral solution                            Y       \n",
       "10611  Oxybutynin 2.5mg/5ml oral solution                            Y       \n",
       "11831  Sodium chloride 292.5mg/5ml (1mmol/ml) oral solution          Y       \n",
       "11832  Sodium chloride 292.5mg/5ml (1mmol/ml) oral solution          Y       \n",
       "11836  Sodium chloride 1.46g/5ml (5mmol/ml) oral solution            Y       \n",
       "11837  Sodium chloride 1.46g/5ml (5mmol/ml) oral solution            Y       \n",
       "11966  Sodium chloride 0.9% / Glucose 5% infusion 500ml bags         Y       \n",
       "11967  Sodium chloride 0.9% / Glucose 5% infusion 500ml bags         Y       \n",
       "12163  Generic Calogen emulsion                                      Y       \n",
       "12164  Generic Calogen emulsion                                      Y       \n",
       "12169  Neocate Advance powder sachets                                Y       \n",
       "12170  Neocate Advance powder sachets                                Y       \n",
       "12669  Gluten free biscuits                                          Y       \n",
       "12670  Gluten free biscuits                                          Y       \n",
       "12867  Low protein pasta                                             Y       \n",
       "12869  Low protein pasta                                             Y       \n",
       "13272  Generic Peptamen liquid                                       Y       \n",
       "13273  Generic Peptamen liquid                                       Y       \n",
       "13274  Generic Seravit Paediatric powder                             Y       \n",
       "13275  Generic Seravit Paediatric powder                             Y       \n",
       "13334  Optifibre powder                                              Y       \n",
       "13335  Optifibre powder                                              Y       \n",
       "13601  Pro-Cal shot starter pack                                     Y       \n",
       "13602  Pro-Cal shot starter pack                                     Y       \n",
       "13804  Mag glycerophos (mag 97.2mg/5ml (4mmol/5ml)) soln             Y       \n",
       "13806  Mag glycerophos (mag 97.2mg/5ml (4mmol/5ml)) soln             Y       \n",
       "13810  Mag glycerophos (mag 121.25mg/5ml (5mmol/5ml)) soln           Y       \n",
       "13812  Mag glycerophos (mag 121.25mg/5ml (5mmol/5ml)) soln           Y       \n",
       "13935  Zinc citrate 50mg capsules                                    Y       \n",
       "13936  Zinc citrate 50mg capsules                                    Y       \n",
       "13964  Selenium 200microgram tablets                                 Y       \n",
       "13965  Selenium 200microgram tablets                                 Y       \n",
       "13967  Selenium 100microgram tablets                                 Y       \n",
       "13968  Selenium 100microgram tablets                                 Y       \n",
       "14279  Ascorbic acid 500mg capsules                                  Y       \n",
       "14280  Ascorbic acid 500mg capsules                                  Y       \n",
       "14368  Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab  Y       \n",
       "14369  Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab  Y       \n",
       "14409  Colecalciferol 15,000units/5ml oral solution                  Y       \n",
       "14410  Colecalciferol 15,000units/5ml oral solution                  Y       \n",
       "14754  Vitamin E 1,000unit capsules                                  Y       \n",
       "14755  Vitamin E 1,000unit capsules                                  Y       \n",
       "14765  Vitamin E 400unit capsules                                    Y       \n",
       "14766  Vitamin E 400unit capsules                                    Y       \n",
       "15247  Glutamine 500mg capsules                                      Y       \n",
       "15248  Glutamine 500mg capsules                                      Y       \n",
       "15255  L-Phenylalanine 500mg capsules                                Y       \n",
       "15256  L-Phenylalanine 500mg capsules                                Y       \n",
       "15431  Glucosamine sulfate 400mg / Chondroitin sulfate 100mg caps    Y       \n",
       "15432  Glucosamine sulfate 400mg / Chondroitin sulfate 100mg caps    Y       \n",
       "15452  Dimethyl sulfone 1g / Ascorbic acid 60mg tablets              Y       \n",
       "15453  Dimethyl sulfone 1g / Ascorbic acid 60mg tablets              Y       \n",
       "16272  Methotrexate 10mg/5ml oral liquid                             Y       \n",
       "16273  Methotrexate 10mg/5ml oral liquid                             Y       \n",
       "16416  Glucosamine hydrochloride 750mg tablets                       Y       \n",
       "16417  Glucosamine hydrochloride 750mg tablets                       Y       \n",
       "16784  Dexamethasone 0.1% eye drops preservative free                Y       \n",
       "16785  Dexamethasone 0.1% eye drops preservative free                Y       \n",
       "17039  Pilocarpine hydrochloride 0.5% eye drops                      Y       \n",
       "17040  Pilocarpine hydrochloride 0.5% eye drops                      Y       \n",
       "17133  Acetylcysteine 10% eye drops preservative free                Y       \n",
       "17134  Acetylcysteine 10% eye drops preservative free                Y       \n",
       "17168  Hypromellose 0.5% eye drops                                   Y       \n",
       "17169  Hypromellose 0.5% eye drops                                   Y       \n",
       "17175  Hypromellose 0.3% eye drops preservative free (drug)          Y       \n",
       "17176  Hypromellose 0.3% eye drops preservative free (drug)          Y       \n",
       "17198  Sodium chloride 5% eye drops preservative free                Y       \n",
       "17199  Sodium chloride 5% eye drops preservative free                Y       \n",
       "17346  Beclometasone 50micrograms/dose nasal spray                   Y       \n",
       "17347  Beclometasone 50micrograms/dose nasal spray                   Y       \n",
       "17360  Budesonide 100micrograms/dose nasal spray                     Y       \n",
       "17361  Budesonide 100micrograms/dose nasal spray                     Y       \n",
       "17520  Amylmetacresol 600microgram lozenges                          Y       \n",
       "17521  Amylmetacresol 600microgram lozenges                          Y       \n",
       "17621  Chlorhexidine gluconate 0.2% mouthwash                        Y       \n",
       "17622  Chlorhexidine gluconate 0.2% mouthwash                        Y       \n",
       "17748  Emulsifying ointment 50% / Liquid paraffin 50% ointment       Y       \n",
       "17750  Emulsifying ointment 50% / Liquid paraffin 50% ointment       Y       \n",
       "17827  Emulsifying ointment                                          Y       \n",
       "17828  Emulsifying ointment                                          Y       \n",
       "17890  Aqueous cream                                                 Y       \n",
       "17891  Aqueous cream                                                 Y       \n",
       "17943  Derma Shield skin protector mousse                            Y       \n",
       "17945  Derma Shield skin protector mousse                            Y       \n",
       "18226  Clobet 0.05%/Oxytetracycline 3% /Nystatin 100,000units/g crm  Y       \n",
       "18227  Clobet 0.05%/Oxytetracycline 3% /Nystatin 100,000units/g crm  Y       \n",
       "18302  Haelan 4micrograms/square cm tape 7.5cm                       Y       \n",
       "18303  Haelan 4micrograms/square cm tape 7.5cm                       Y       \n",
       "18661  Salicylic acid 5% ointment in a base                          Y       \n",
       "18662  Salicylic acid 5% ointment in a base                          Y       \n",
       "18873  Salicylic acid 20% ointment                                   Y       \n",
       "18874  Salicylic acid 20% ointment                                   Y       \n",
       "19134  Amorolfine 5% medicated nail lacquer                          Y       \n",
       "19135  Amorolfine 5% medicated nail lacquer                          Y       \n",
       "19541  Hepatitis A vaccine (inactivated, adsorbed) inj 0.5ml pfs     Y       \n",
       "19542  Hepatitis A vaccine (inactivated, adsorbed) inj 0.5ml pfs     Y       \n",
       "19612  dTAP/IPV inj 0.5ml pfs                                        Y       \n",
       "19613  dTAP/IPV inj 0.5ml pfs                                        Y       \n",
       "19616  DTaP/IPV vacc (ads) inj 0.5ml pfs                             Y       \n",
       "19617  DTaP/IPV vacc (ads) inj 0.5ml pfs                             Y       \n",
       "19891  Lidocaine 2% and Chlorhexidine gel                            Y       \n",
       "19893  Lidocaine 2% and Chlorhexidine gel                            Y       \n",
       "20585  Absorbent cotton BP 1988                                      Y       \n",
       "20586  Absorbent cotton BP 1988                                      Y       \n",
       "21659  IntraSite Gel dressing                                        Y       \n",
       "21660  IntraSite Gel dressing                                        Y       \n",
       "21680  Iodoflex paste dressing                                       Y       \n",
       "21681  Iodoflex paste dressing                                       Y       \n",
       "21687  Cutimed Gel dressing                                          Y       \n",
       "21688  Cutimed Gel dressing                                          Y       \n",
       "22592  Alhydran cream                                                Y       \n",
       "22593  Alhydran cream                                                Y       \n",
       "23116  Silgen Ag spray                                               Y       \n",
       "23117  Silgen Ag spray                                               Y       \n",
       "23790  Absorbent lint BPC                                            Y       \n",
       "23791  Absorbent lint BPC                                            Y       \n",
       "23853  Comfifast stockinette 5cm                                     Y       \n",
       "23854  Comfifast stockinette 5cm                                     Y       \n",
       "23856  Comfifast stockinette 7.5cm                                   Y       \n",
       "23857  Comfifast stockinette 7.5cm                                   Y       \n",
       "23859  Comfifast stockinette 10.75cm                                 Y       \n",
       "23860  Comfifast stockinette 10.75cm                                 Y       \n",
       "23865  Acti-Fast 2-way stretch stockinette 5cm                       Y       \n",
       "23866  Acti-Fast 2-way stretch stockinette 5cm                       Y       \n",
       "23868  Acti-Fast 2-way stretch stockinette 7.5cm                     Y       \n",
       "23869  Acti-Fast 2-way stretch stockinette 7.5cm                     Y       \n",
       "23871  Acti-Fast 2-way stretch stockinette 10.75cm                   Y       \n",
       "23872  Acti-Fast 2-way stretch stockinette 10.75cm                   Y       \n",
       "23874  Tubifast 2-way stretch stockinette 5cm                        Y       \n",
       "23875  Tubifast 2-way stretch stockinette 5cm                        Y       \n",
       "23877  Tubifast 2-way stretch stockinette 7.5cm                      Y       \n",
       "23878  Tubifast 2-way stretch stockinette 7.5cm                      Y       \n",
       "23880  Tubifast 2-way stretch stockinette 10.75cm                    Y       \n",
       "23881  Tubifast 2-way stretch stockinette 10.75cm                    Y       \n",
       "23931  Coverflex stockinette 5cm                                     Y       \n",
       "23932  Coverflex stockinette 5cm                                     Y       \n",
       "23934  Coverflex stockinette 7.5cm                                   Y       \n",
       "23935  Coverflex stockinette 7.5cm                                   Y       \n",
       "23937  Coverflex stockinette 10.75cm                                 Y       \n",
       "23938  Coverflex stockinette 10.75cm                                 Y       \n",
       "23972  Easifast stockinette 5cm                                      Y       \n",
       "23973  Easifast stockinette 5cm                                      Y       \n",
       "23975  Easifast stockinette 7.5cm                                    Y       \n",
       "23976  Easifast stockinette 7.5cm                                    Y       \n",
       "23978  Easifast stockinette 10.75cm                                  Y       \n",
       "23979  Easifast stockinette 10.75cm                                  Y       \n",
       "23989  CliniFast stockinette 5cm                                     Y       \n",
       "23990  CliniFast stockinette 5cm                                     Y       \n",
       "23992  CliniFast stockinette 7.5cm                                   Y       \n",
       "23993  CliniFast stockinette 7.5cm                                   Y       \n",
       "23995  CliniFast stockinette 10.75cm                                 Y       \n",
       "23996  CliniFast stockinette 10.75cm                                 Y       \n",
       "24069  Comfifast MultiStretch 2-way stretch stockinette 5cm          Y       \n",
       "24070  Comfifast MultiStretch 2-way stretch stockinette 5cm          Y       \n",
       "24072  Comfifast MultiStretch 2-way stretch stockinette 7.5cm        Y       \n",
       "24073  Comfifast MultiStretch 2-way stretch stockinette 7.5cm        Y       \n",
       "24075  Comfifast MultiStretch 2-way stretch stockinette 10.75cm      Y       \n",
       "24076  Comfifast MultiStretch 2-way stretch stockinette 10.75cm      Y       \n",
       "24177  Fortuna Fast stockinette 5cm                                  Y       \n",
       "24178  Fortuna Fast stockinette 5cm                                  Y       \n",
       "24180  Fortuna Fast stockinette 7.5cm                                Y       \n",
       "24181  Fortuna Fast stockinette 7.5cm                                Y       \n",
       "24183  Fortuna Fast stockinette 10.75cm                              Y       \n",
       "24184  Fortuna Fast stockinette 10.75cm                              Y       \n",
       "24248  Flexifast stockinette 7.5cm                                   Y       \n",
       "24249  Flexifast stockinette 7.5cm                                   Y       \n",
       "24251  Flexifast stockinette 10.75cm                                 Y       \n",
       "24252  Flexifast stockinette 10.75cm                                 Y       \n",
       "26107  OptiLube sterile lubricating jelly                            Y       \n",
       "26109  OptiLube sterile lubricating jelly                            Y       \n",
       "26349  Jobst FarrowWrap 4000 compression system                      Y       \n",
       "26350  Jobst FarrowWrap 4000 compression system                      Y       \n",
       "26473  Elave Intensive cream                                         Y       \n",
       "26474  Elave Intensive cream                                         Y       \n",
       "26486  MyriBase gel                                                  Y       \n",
       "26487  MyriBase gel                                                  Y       \n",
       "26502  Aquadrate 10% cream                                           Y       \n",
       "26504  Aquadrate 10% cream                                           Y       \n",
       "26505  Hydromol Intensive 10% cream                                  Y       \n",
       "26507  Hydromol Intensive 10% cream                                  Y       \n",
       "26535  Diprobase cream                                               Y       \n",
       "26537  Diprobase cream                                               Y       \n",
       "30542  Adapt No-Sting medical adhesive remover aerosol               Y       \n",
       "30543  Adapt No-Sting medical adhesive remover aerosol               Y       \n",
       "34130  Day-drop deodorant                                            Y       \n",
       "34131  Day-drop deodorant                                            Y       \n",
       "35956  Adapt paste                                                   Y       \n",
       "35957  Adapt paste                                                   Y       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "new_codes_mapping_to_2_new_codes = [code for code, count in new_code_counts.items() if count == 2]\n",
    "\n",
    "with pd.option_context('display.max_rows', None):\n",
    "    display(bnf_mapping[bnf_mapping[\"new_code\"].isin(new_codes_mapping_to_2_new_codes)].sort_values(['new_code', 'old_code']))"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Again, there are some patterns we can pick out:"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### An old version of a presentation is combined with the current version of the same"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>224</th>\n",
       "      <td>0102000ACAAAPAP</td>\n",
       "      <td>Atrop Sulf_Oral Susp 500mcg/5ml</td>\n",
       "      <td>0102000ACAABABA</td>\n",
       "      <td>Atropine 500micrograms/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>226</th>\n",
       "      <td>0102000ACAABBBB</td>\n",
       "      <td>Atrop Sulf_Oral Soln 500mcg/5ml (Old)</td>\n",
       "      <td>0102000ACAABABA</td>\n",
       "      <td>Atropine 500micrograms/5ml oral solution</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "            old_code                               old_name         new_code  \\\n",
       "224  0102000ACAAAPAP  Atrop Sulf_Oral Susp 500mcg/5ml        0102000ACAABABA   \n",
       "226  0102000ACAABBBB  Atrop Sulf_Oral Soln 500mcg/5ml (Old)  0102000ACAABABA   \n",
       "\n",
       "                                     new_name changed  \n",
       "224  Atropine 500micrograms/5ml oral solution  Y       \n",
       "226  Atropine 500micrograms/5ml oral solution  Y       "
      ]
     },
     "execution_count": 18,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"new_code\"] == \"0102000ACAABABA\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### An \"Oral Soln\" presentation is combined with an \"Oral Susp\" presentation"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>248</th>\n",
       "      <td>0102000L0AAAWAW</td>\n",
       "      <td>Glycopyrronium Brom_Oral Soln 1mg/5ml</td>\n",
       "      <td>0102000L0AAADAD</td>\n",
       "      <td>Glycopyrronium bromide 1mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>249</th>\n",
       "      <td>0102000L0AAAXAX</td>\n",
       "      <td>Glycopyrronium Brom_Oral Susp 1mg/5ml</td>\n",
       "      <td>0102000L0AAADAD</td>\n",
       "      <td>Glycopyrronium bromide 1mg/5ml oral liquid</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "            old_code                               old_name         new_code  \\\n",
       "248  0102000L0AAAWAW  Glycopyrronium Brom_Oral Soln 1mg/5ml  0102000L0AAADAD   \n",
       "249  0102000L0AAAXAX  Glycopyrronium Brom_Oral Susp 1mg/5ml  0102000L0AAADAD   \n",
       "\n",
       "                                       new_name changed  \n",
       "248  Glycopyrronium bromide 1mg/5ml oral liquid  Y       \n",
       "249  Glycopyrronium bromide 1mg/5ml oral liquid  Y       "
      ]
     },
     "execution_count": 19,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"new_code\"] == \"0102000L0AAADAD\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Presentations of different flavour are combined"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>721</th>\n",
       "      <td>0106010E0AAAHAH</td>\n",
       "      <td>Ispag Husk_Gran Eff Sach 3.5g Orange S/F</td>\n",
       "      <td>0106010E0AAADAD</td>\n",
       "      <td>Ispaghula husk 3.5g efferv gran sach gluten free sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>722</th>\n",
       "      <td>0106010E0AAANAN</td>\n",
       "      <td>Ispag Husk_Gran Eff Sach 3.5g Lem S/F</td>\n",
       "      <td>0106010E0AAADAD</td>\n",
       "      <td>Ispaghula husk 3.5g efferv gran sach gluten free sugar free</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "            old_code                                  old_name  \\\n",
       "721  0106010E0AAAHAH  Ispag Husk_Gran Eff Sach 3.5g Orange S/F   \n",
       "722  0106010E0AAANAN  Ispag Husk_Gran Eff Sach 3.5g Lem S/F      \n",
       "\n",
       "            new_code  \\\n",
       "721  0106010E0AAADAD   \n",
       "722  0106010E0AAADAD   \n",
       "\n",
       "                                                        new_name changed  \n",
       "721  Ispaghula husk 3.5g efferv gran sach gluten free sugar free  Y       \n",
       "722  Ispaghula husk 3.5g efferv gran sach gluten free sugar free  Y       "
      ]
     },
     "execution_count": 20,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"new_code\"] == \"0106010E0AAADAD\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Presentations of different dose size are combined"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>2197</th>\n",
       "      <td>0206010F0BFADCI</td>\n",
       "      <td>Nitrolingual_P/Spy 400mcg (180 D)</td>\n",
       "      <td>0206010F0BFABCJ</td>\n",
       "      <td>Nitrolingual 400micrograms/dose pump sublingual spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2198</th>\n",
       "      <td>0206010F0BFAECK</td>\n",
       "      <td>Nitrolingual_P/Spy 400mcg (75 D)</td>\n",
       "      <td>0206010F0BFABCJ</td>\n",
       "      <td>Nitrolingual 400micrograms/dose pump sublingual spray</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "             old_code                           old_name         new_code  \\\n",
       "2197  0206010F0BFADCI  Nitrolingual_P/Spy 400mcg (180 D)  0206010F0BFABCJ   \n",
       "2198  0206010F0BFAECK  Nitrolingual_P/Spy 400mcg (75 D)   0206010F0BFABCJ   \n",
       "\n",
       "                                                   new_name changed  \n",
       "2197  Nitrolingual 400micrograms/dose pump sublingual spray  Y       \n",
       "2198  Nitrolingual 400micrograms/dose pump sublingual spray  Y       "
      ]
     },
     "execution_count": 21,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"new_code\"] == \"0206010F0BFABCJ\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Branded presentations are combined into a generic presentation"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>old_code</th>\n",
       "      <th>old_name</th>\n",
       "      <th>new_code</th>\n",
       "      <th>new_name</th>\n",
       "      <th>changed</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>13964</th>\n",
       "      <td>090504700BBDGBC</td>\n",
       "      <td>Solgar_Selenium Tab 200mcg</td>\n",
       "      <td>090504700AABCBC</td>\n",
       "      <td>Selenium 200microgram tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13965</th>\n",
       "      <td>090504700BBFDBC</td>\n",
       "      <td>HealthAid_Selenium Tab 200mcg</td>\n",
       "      <td>090504700AABCBC</td>\n",
       "      <td>Selenium 200microgram tablets</td>\n",
       "      <td>Y</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "              old_code                       old_name         new_code  \\\n",
       "13964  090504700BBDGBC  Solgar_Selenium Tab 200mcg     090504700AABCBC   \n",
       "13965  090504700BBFDBC  HealthAid_Selenium Tab 200mcg  090504700AABCBC   \n",
       "\n",
       "                            new_name changed  \n",
       "13964  Selenium 200microgram tablets  Y       \n",
       "13965  Selenium 200microgram tablets  Y       "
      ]
     },
     "execution_count": 22,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bnf_mapping[bnf_mapping[\"new_code\"] == \"090504700AABCBC\"]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Total items and net_cost for each presentation affected by change 1 for November 2019"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>name</th>\n",
       "      <th>items</th>\n",
       "      <th>net_cost</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>bnf_code</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>090402000BBZGA0</th>\n",
       "      <td>Aymes Shake_Pdr Sach 57g (Choc)</td>\n",
       "      <td>2100</td>\n",
       "      <td>35708.40</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21220000227</th>\n",
       "      <td>Zerolatum Bath Add</td>\n",
       "      <td>2277</td>\n",
       "      <td>11883.99</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21220000233</th>\n",
       "      <td>Cetraben Crm 50g</td>\n",
       "      <td>3703</td>\n",
       "      <td>25562.71</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1202010M0AAACAC</th>\n",
       "      <td>Fluticasone Prop_Nsl Spy 50mcg (150 D)</td>\n",
       "      <td>33827</td>\n",
       "      <td>273936.93</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20090000941</th>\n",
       "      <td>CliniFast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr</td>\n",
       "      <td>3097</td>\n",
       "      <td>23247.00</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                                                                      name  \\\n",
       "bnf_code                                                                     \n",
       "090402000BBZGA0  Aymes Shake_Pdr Sach 57g (Choc)                             \n",
       "21220000227      Zerolatum Bath Add                                          \n",
       "21220000233      Cetraben Crm 50g                                            \n",
       "1202010M0AAACAC  Fluticasone Prop_Nsl Spy 50mcg (150 D)                      \n",
       "20090000941      CliniFast 7.5cm x 5m (Blue) Stkntte Elasctd Viscose Tublr   \n",
       "\n",
       "                 items   net_cost  \n",
       "bnf_code                           \n",
       "090402000BBZGA0  2100   35708.40   \n",
       "21220000227      2277   11883.99   \n",
       "21220000233      3703   25562.71   \n",
       "1202010M0AAACAC  33827  273936.93  \n",
       "20090000941      3097   23247.00   "
      ]
     },
     "execution_count": 23,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "joined_bnf_codes = \", \".join(\"'{}'\".format(bnf_code) for bnf_code in bnf_mapping[\"old_code\"])\n",
    "\n",
    "sql = \"\"\"\n",
    "SELECT\n",
    "    p.bnf_code,\n",
    "    p.name,\n",
    "    SUM(rx.items) AS items,\n",
    "    SUM(rx.net_cost_pence) / 100 AS net_cost\n",
    "FROM public_draft.prescribing rx\n",
    "INNER JOIN public_draft.presentation p\n",
    "    ON rx.bnf_code = p.bnf_code\n",
    "WHERE rx.month = '2019-11-01'\n",
    "  AND p.bnf_code IN ({})\n",
    "GROUP BY p.bnf_code, p.name\n",
    "\"\"\".format(joined_bnf_codes)\n",
    "\n",
    "df1 = bq.cached_read(sql, csv_path='../bq-cache/2019_11_items_and_spending1.csv')\n",
    "df1.set_index('bnf_code', inplace=True)\n",
    "df1.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "metadata": {},
   "outputs": [],
   "source": [
    "items1, net_cost1 = df1['items'], df1['net_cost']"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Percentage of items and net_cost that are affected by change 1"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1.3122145971679895"
      ]
     },
     "execution_count": 25,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "items1.sum() / total_items * 100"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 26,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1.4312732104979142"
      ]
     },
     "execution_count": 26,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "net_cost1.sum() / total_net_cost * 100"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Distribution of presentations affected by change 1, by items"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 27,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "0.01 0.5469690625575322\n",
      "0.05 0.7838533562946104\n",
      "0.1 0.8878014685876371\n",
      "0.2 0.963701577257257\n"
     ]
    }
   ],
   "source": [
    "# Find the proprtion of presentations accounted for by the top 1%, 5%, 10%, 20% of prescribing, by items\n",
    "for percentile in [0.01, 0.05, 0.1, 0.2]:\n",
    "    print(percentile, items1[items1 > items1.quantile(1 - percentile)].sum() / items1.sum())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 28,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "ax = items1.sort_values().cumsum().reset_index().plot()\n",
    "ax.set_ylim(0);"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Top 10 presentations affected by change 1, by items"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 29,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>name</th>\n",
       "      <th>items</th>\n",
       "      <th>net_cost</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>bnf_code</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0906026M0AAAGAG</th>\n",
       "      <td>Thiamine HCl_Tab 100mg</td>\n",
       "      <td>216610</td>\n",
       "      <td>546200.82</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0906027G0AAABAB</th>\n",
       "      <td>Vit B Co Strong_Tab</td>\n",
       "      <td>143969</td>\n",
       "      <td>471005.47</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21220000235</th>\n",
       "      <td>Cetraben Crm 500g</td>\n",
       "      <td>94487</td>\n",
       "      <td>636215.76</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21220000242</th>\n",
       "      <td>Epimax Crm 500g</td>\n",
       "      <td>72203</td>\n",
       "      <td>192340.70</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0407010H0AAAAAA</th>\n",
       "      <td>Paracet_Cap 500mg</td>\n",
       "      <td>61869</td>\n",
       "      <td>207848.16</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21300000702</th>\n",
       "      <td>Clinitas Carbomer Eye Gel</td>\n",
       "      <td>48480</td>\n",
       "      <td>102789.14</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1202010M0AAACAC</th>\n",
       "      <td>Fluticasone Prop_Nsl Spy 50mcg (150 D)</td>\n",
       "      <td>33827</td>\n",
       "      <td>273936.93</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23803108006</th>\n",
       "      <td>3m Health Care_Cavilon Durable Barrier Crm 92g</td>\n",
       "      <td>31552</td>\n",
       "      <td>251428.39</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21220000230</th>\n",
       "      <td>Zerodouble Gel</td>\n",
       "      <td>24672</td>\n",
       "      <td>137567.10</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0501011P0AAAFAF</th>\n",
       "      <td>Phenoxymethylpenicillin_Soln 250mg/5ml</td>\n",
       "      <td>21354</td>\n",
       "      <td>223958.71</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                                                           name   items  \\\n",
       "bnf_code                                                                  \n",
       "0906026M0AAAGAG  Thiamine HCl_Tab 100mg                          216610   \n",
       "0906027G0AAABAB  Vit B Co Strong_Tab                             143969   \n",
       "21220000235      Cetraben Crm 500g                               94487    \n",
       "21220000242      Epimax Crm 500g                                 72203    \n",
       "0407010H0AAAAAA  Paracet_Cap 500mg                               61869    \n",
       "21300000702      Clinitas Carbomer Eye Gel                       48480    \n",
       "1202010M0AAACAC  Fluticasone Prop_Nsl Spy 50mcg (150 D)          33827    \n",
       "23803108006      3m Health Care_Cavilon Durable Barrier Crm 92g  31552    \n",
       "21220000230      Zerodouble Gel                                  24672    \n",
       "0501011P0AAAFAF  Phenoxymethylpenicillin_Soln 250mg/5ml          21354    \n",
       "\n",
       "                  net_cost  \n",
       "bnf_code                    \n",
       "0906026M0AAAGAG  546200.82  \n",
       "0906027G0AAABAB  471005.47  \n",
       "21220000235      636215.76  \n",
       "21220000242      192340.70  \n",
       "0407010H0AAAAAA  207848.16  \n",
       "21300000702      102789.14  \n",
       "1202010M0AAACAC  273936.93  \n",
       "23803108006      251428.39  \n",
       "21220000230      137567.10  \n",
       "0501011P0AAAFAF  223958.71  "
      ]
     },
     "execution_count": 29,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df1.sort_values(['items'], ascending=False).head(10)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Distribution of presentations affected by change 1, by net_cost"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 30,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "0.01 0.29625967968164973\n",
      "0.05 0.6613395896681702\n",
      "0.1 0.8151351449011885\n",
      "0.2 0.9391461893678298\n"
     ]
    }
   ],
   "source": [
    "# Find the proprtion of presentations accounted for by the top 1%, 5%, 10%, 20% of prescribing, by net_cost\n",
    "for percentile in [0.01, 0.05, 0.1, 0.2]:\n",
    "    print(percentile, net_cost1[net_cost1 > net_cost1.quantile(1 - percentile)].sum() / net_cost1.sum())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 31,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "ax = net_cost1.sort_values().cumsum().reset_index().plot()\n",
    "ax.set_ylim(0);"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Top 10 presentations affected by change 1, by net_cost"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 32,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>name</th>\n",
       "      <th>items</th>\n",
       "      <th>net_cost</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>bnf_code</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>090402000BBLMA0</th>\n",
       "      <td>Nutrison Pack_Energy M/Fibre</td>\n",
       "      <td>2082</td>\n",
       "      <td>666942.32</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21220000235</th>\n",
       "      <td>Cetraben Crm 500g</td>\n",
       "      <td>94487</td>\n",
       "      <td>636215.76</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0906026M0AAAGAG</th>\n",
       "      <td>Thiamine HCl_Tab 100mg</td>\n",
       "      <td>216610</td>\n",
       "      <td>546200.82</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0906027G0AAABAB</th>\n",
       "      <td>Vit B Co Strong_Tab</td>\n",
       "      <td>143969</td>\n",
       "      <td>471005.47</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>090402000BBGYA0</th>\n",
       "      <td>Nutrison Pack_Energy</td>\n",
       "      <td>1236</td>\n",
       "      <td>343100.29</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1202020L0AACCCC</th>\n",
       "      <td>Sod Chlor_Inh Soln 0.9% 2.5ml Ud Amp</td>\n",
       "      <td>8081</td>\n",
       "      <td>279162.33</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1202010M0AAACAC</th>\n",
       "      <td>Fluticasone Prop_Nsl Spy 50mcg (150 D)</td>\n",
       "      <td>33827</td>\n",
       "      <td>273936.93</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>090402000BBGXA0</th>\n",
       "      <td>Nutrison Pack_Conc Liq</td>\n",
       "      <td>690</td>\n",
       "      <td>271235.45</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23803108006</th>\n",
       "      <td>3m Health Care_Cavilon Durable Barrier Crm 92g</td>\n",
       "      <td>31552</td>\n",
       "      <td>251428.39</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1202010Y0BBAAAA</th>\n",
       "      <td>Dymista_Nsl Spy 50mcg/137mcg (120 D)</td>\n",
       "      <td>15323</td>\n",
       "      <td>247796.40</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                                                           name   items  \\\n",
       "bnf_code                                                                  \n",
       "090402000BBLMA0  Nutrison Pack_Energy M/Fibre                    2082     \n",
       "21220000235      Cetraben Crm 500g                               94487    \n",
       "0906026M0AAAGAG  Thiamine HCl_Tab 100mg                          216610   \n",
       "0906027G0AAABAB  Vit B Co Strong_Tab                             143969   \n",
       "090402000BBGYA0  Nutrison Pack_Energy                            1236     \n",
       "1202020L0AACCCC  Sod Chlor_Inh Soln 0.9% 2.5ml Ud Amp            8081     \n",
       "1202010M0AAACAC  Fluticasone Prop_Nsl Spy 50mcg (150 D)          33827    \n",
       "090402000BBGXA0  Nutrison Pack_Conc Liq                          690      \n",
       "23803108006      3m Health Care_Cavilon Durable Barrier Crm 92g  31552    \n",
       "1202010Y0BBAAAA  Dymista_Nsl Spy 50mcg/137mcg (120 D)            15323    \n",
       "\n",
       "                  net_cost  \n",
       "bnf_code                    \n",
       "090402000BBLMA0  666942.32  \n",
       "21220000235      636215.76  \n",
       "0906026M0AAAGAG  546200.82  \n",
       "0906027G0AAABAB  471005.47  \n",
       "090402000BBGYA0  343100.29  \n",
       "1202020L0AACCCC  279162.33  \n",
       "1202010M0AAACAC  273936.93  \n",
       "090402000BBGXA0  271235.45  \n",
       "23803108006      251428.39  \n",
       "1202010Y0BBAAAA  247796.40  "
      ]
     },
     "execution_count": 32,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df1.sort_values(['net_cost'], ascending=False).head(10)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Change 2: special container quantity changes"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Affected presentations"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 33,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "There are 1822 changed records\n"
     ]
    },
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>BNF Code</th>\n",
       "      <th>dm+d: BNF Description</th>\n",
       "      <th>MDR Quantity</th>\n",
       "      <th>dm+d:  Quantity</th>\n",
       "      <th>dm+d:  PACK Information</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>0106050B0BEAAA0</td>\n",
       "      <td>Moviprep oral powder sachets</td>\n",
       "      <td>1.0</td>\n",
       "      <td>4.0</td>\n",
       "      <td>4 sachets</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>0106050B0BEABA0</td>\n",
       "      <td>Moviprep Orange oral powder sachets</td>\n",
       "      <td>1.0</td>\n",
       "      <td>4.0</td>\n",
       "      <td>4 sachets</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>0107020J0AAAJAJ</td>\n",
       "      <td>Lidocaine 1% / Hydrocortisone 0.2% spray</td>\n",
       "      <td>1.0</td>\n",
       "      <td>30.0</td>\n",
       "      <td>30 mls</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>0107020J0BHAAAJ</td>\n",
       "      <td>Perinal spray</td>\n",
       "      <td>1.0</td>\n",
       "      <td>30.0</td>\n",
       "      <td>30 mls</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>0107020J0BJAAAJ</td>\n",
       "      <td>Germoloids HC spray</td>\n",
       "      <td>1.0</td>\n",
       "      <td>30.0</td>\n",
       "      <td>30 mls</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "          BNF Code                     dm+d: BNF Description  MDR Quantity  \\\n",
       "0  0106050B0BEAAA0  Moviprep oral powder sachets              1.0            \n",
       "1  0106050B0BEABA0  Moviprep Orange oral powder sachets       1.0            \n",
       "2  0107020J0AAAJAJ  Lidocaine 1% / Hydrocortisone 0.2% spray  1.0            \n",
       "3  0107020J0BHAAAJ  Perinal spray                             1.0            \n",
       "4  0107020J0BJAAAJ  Germoloids HC spray                       1.0            \n",
       "\n",
       "   dm+d:  Quantity dm+d:  PACK Information  \n",
       "0  4.0              4 sachets               \n",
       "1  4.0              4 sachets               \n",
       "2  30.0             30 mls                  \n",
       "3  30.0             30 mls                  \n",
       "4  30.0             30 mls                  "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "quantity_change = pd.read_excel('../data/Special Container size mismatch between MDR and dm+d latest.xlsx')\n",
    "print(f\"There are {len(quantity_change)} changed records\")\n",
    "display(quantity_change.head())"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Total items and net_cost for each presentation affected by change 2 for November 2019"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 34,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>name</th>\n",
       "      <th>items</th>\n",
       "      <th>net_cost</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>bnf_code</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>21300000108</th>\n",
       "      <td>Hyabak Sod Hyaluronate Eye Dps 10ml P/F</td>\n",
       "      <td>15528</td>\n",
       "      <td>162125.09</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21300000401</th>\n",
       "      <td>Liquifilm 1.4% Polyvinyl Alcohol Eye Dps 15ml</td>\n",
       "      <td>11656</td>\n",
       "      <td>29085.10</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21300000711</th>\n",
       "      <td>Xailin Night Paraf Eye Oint P/F 5g</td>\n",
       "      <td>43421</td>\n",
       "      <td>156743.40</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23150901504</th>\n",
       "      <td>CliniMed_Appeel No Sting Medical Adh Remover A/Spy 50ml</td>\n",
       "      <td>6317</td>\n",
       "      <td>183511.12</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1203010E0AAABAB</th>\n",
       "      <td>Benzydamine HCl_Spy 0.15% 30ml S/F</td>\n",
       "      <td>21406</td>\n",
       "      <td>67182.84</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                                                                    name  \\\n",
       "bnf_code                                                                   \n",
       "21300000108      Hyabak Sod Hyaluronate Eye Dps 10ml P/F                   \n",
       "21300000401      Liquifilm 1.4% Polyvinyl Alcohol Eye Dps 15ml             \n",
       "21300000711      Xailin Night Paraf Eye Oint P/F 5g                        \n",
       "23150901504      CliniMed_Appeel No Sting Medical Adh Remover A/Spy 50ml   \n",
       "1203010E0AAABAB  Benzydamine HCl_Spy 0.15% 30ml S/F                        \n",
       "\n",
       "                 items   net_cost  \n",
       "bnf_code                           \n",
       "21300000108      15528  162125.09  \n",
       "21300000401      11656  29085.10   \n",
       "21300000711      43421  156743.40  \n",
       "23150901504      6317   183511.12  \n",
       "1203010E0AAABAB  21406  67182.84   "
      ]
     },
     "execution_count": 34,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "joined_bnf_codes = \", \".join(\"'{}'\".format(bnf_code) for bnf_code in quantity_change['BNF Code'])\n",
    "\n",
    "sql = \"\"\"\n",
    "SELECT\n",
    "    p.bnf_code,\n",
    "    p.name,\n",
    "    SUM(rx.items) AS items,\n",
    "    SUM(rx.net_cost_pence) / 100 AS net_cost\n",
    "FROM public_draft.prescribing rx\n",
    "INNER JOIN public_draft.presentation p\n",
    "    ON rx.bnf_code = p.bnf_code\n",
    "WHERE rx.month = '2019-11-01'\n",
    "  AND p.bnf_code IN ({})\n",
    "GROUP BY p.bnf_code, p.name\n",
    "\"\"\".format(joined_bnf_codes)\n",
    "\n",
    "df2 = bq.cached_read(sql, csv_path='../bq-cache/2019_11_items_and_spending2.csv')\n",
    "df2.set_index('bnf_code', inplace=True)\n",
    "df2.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 35,
   "metadata": {},
   "outputs": [],
   "source": [
    "items2, net_cost2 = df2['items'], df2['net_cost']"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Percentage of items and net_cost that are affected by change 2"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 36,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1.4898494160168612"
      ]
     },
     "execution_count": 36,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "items2.sum() / total_items * 100"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 37,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "3.2417807563555776"
      ]
     },
     "execution_count": 37,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "net_cost2.sum() / total_net_cost * 100"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Distribution of presentations affected by change 2, by items"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 38,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "0.01 0.4380237215973298\n",
      "0.05 0.7494982963240924\n",
      "0.1 0.8655276301147049\n",
      "0.2 0.9481320551518887\n"
     ]
    }
   ],
   "source": [
    "# Find the proprtion of presentations accounted for by the top 1%, 5%, 10%, 20% of prescribing, by items\n",
    "for percentile in [0.01, 0.05, 0.1, 0.2]:\n",
    "    print(percentile, items2[items2 > items2.quantile(1 - percentile)].sum() / items2.sum())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 39,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "ax = items2.sort_values().cumsum().reset_index().plot()\n",
    "ax.set_ylim(0);"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Top 10 presentations affected by change 2, by items"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 40,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>name</th>\n",
       "      <th>items</th>\n",
       "      <th>net_cost</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>bnf_code</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>1108010F0AAAAAA</th>\n",
       "      <td>Hypromellose_Eye Dps 0.3%</td>\n",
       "      <td>118151</td>\n",
       "      <td>156821.91</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>120101050BCAAAB</th>\n",
       "      <td>Otomize_Ear Spy 5ml</td>\n",
       "      <td>112613</td>\n",
       "      <td>398207.52</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21300000111</th>\n",
       "      <td>Hylo-Forte Sod Hyaluronate Eye Dps 0.2% P/F 10ml</td>\n",
       "      <td>82955</td>\n",
       "      <td>1033619.00</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1106000ACAAAAAA</th>\n",
       "      <td>Brinzolamide_Eye Dps 10mg/ml</td>\n",
       "      <td>73444</td>\n",
       "      <td>254184.56</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21220000311</th>\n",
       "      <td>Diprobase Crm 500g (App)</td>\n",
       "      <td>43775</td>\n",
       "      <td>324351.84</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21300000711</th>\n",
       "      <td>Xailin Night Paraf Eye Oint P/F 5g</td>\n",
       "      <td>43421</td>\n",
       "      <td>156743.40</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23804708007</th>\n",
       "      <td>Smith &amp; Nephew_Proshield Plus Skin Prote 115g</td>\n",
       "      <td>41716</td>\n",
       "      <td>536024.44</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21300000104</th>\n",
       "      <td>Hylo-Tear Sod Hyaluronate Eye Dps 0.1% P/F 10ml</td>\n",
       "      <td>38514</td>\n",
       "      <td>417520.00</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0301020S0BBAAAA</th>\n",
       "      <td>Seebri_Breezhaler Inh Cap 55mcg + Dev</td>\n",
       "      <td>29304</td>\n",
       "      <td>921215.28</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23803068001</th>\n",
       "      <td>Medicareplus_Medi Derma-S Barrier Crm 90g</td>\n",
       "      <td>26603</td>\n",
       "      <td>188496.00</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                                                             name   items  \\\n",
       "bnf_code                                                                    \n",
       "1108010F0AAAAAA  Hypromellose_Eye Dps 0.3%                         118151   \n",
       "120101050BCAAAB  Otomize_Ear Spy 5ml                               112613   \n",
       "21300000111      Hylo-Forte Sod Hyaluronate Eye Dps 0.2% P/F 10ml  82955    \n",
       "1106000ACAAAAAA  Brinzolamide_Eye Dps 10mg/ml                      73444    \n",
       "21220000311      Diprobase Crm 500g (App)                          43775    \n",
       "21300000711      Xailin Night Paraf Eye Oint P/F 5g                43421    \n",
       "23804708007      Smith & Nephew_Proshield Plus Skin Prote 115g     41716    \n",
       "21300000104      Hylo-Tear Sod Hyaluronate Eye Dps 0.1% P/F 10ml   38514    \n",
       "0301020S0BBAAAA  Seebri_Breezhaler Inh Cap 55mcg + Dev             29304    \n",
       "23803068001      Medicareplus_Medi Derma-S Barrier Crm 90g         26603    \n",
       "\n",
       "                   net_cost  \n",
       "bnf_code                     \n",
       "1108010F0AAAAAA  156821.91   \n",
       "120101050BCAAAB  398207.52   \n",
       "21300000111      1033619.00  \n",
       "1106000ACAAAAAA  254184.56   \n",
       "21220000311      324351.84   \n",
       "21300000711      156743.40   \n",
       "23804708007      536024.44   \n",
       "21300000104      417520.00   \n",
       "0301020S0BBAAAA  921215.28   \n",
       "23803068001      188496.00   "
      ]
     },
     "execution_count": 40,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df2.sort_values(['items'], ascending=False).head(10)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Distribution of presentations affected by change 2, by net_cost"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 41,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "0.01 0.3149874674118635\n",
      "0.05 0.7015026780245146\n",
      "0.1 0.8425765622116822\n",
      "0.2 0.9406182197270274\n"
     ]
    }
   ],
   "source": [
    "# Find the proprtion of presentations accounted for by the top 1%, 5%, 10%, 20% of prescribing, by net_cost\n",
    "for percentile in [0.01, 0.05, 0.1, 0.2]:\n",
    "    print(percentile, net_cost2[net_cost2 > net_cost2.quantile(1 - percentile)].sum() / net_cost2.sum())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 42,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "ax = net_cost2.sort_values().cumsum().reset_index().plot()\n",
    "ax.set_ylim(0);"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Top 10 presentations affected by change 2, by net_cost"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>name</th>\n",
       "      <th>items</th>\n",
       "      <th>net_cost</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>bnf_code</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>21300000111</th>\n",
       "      <td>Hylo-Forte Sod Hyaluronate Eye Dps 0.2% P/F 10ml</td>\n",
       "      <td>82955</td>\n",
       "      <td>1033619.00</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21020001196</th>\n",
       "      <td>Coloplast SpeediCath Compact Male OneSize 12/18(30-Pack)Cath</td>\n",
       "      <td>4624</td>\n",
       "      <td>1014858.96</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0301020S0BBAAAA</th>\n",
       "      <td>Seebri_Breezhaler Inh Cap 55mcg + Dev</td>\n",
       "      <td>29304</td>\n",
       "      <td>921215.28</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>190700000BBCJA0</th>\n",
       "      <td>Resource_ThickenUp Clr Pdr</td>\n",
       "      <td>18710</td>\n",
       "      <td>854096.22</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21020001190</th>\n",
       "      <td>Coloplast SpeediCath Compact Fle Size 8-14 (30-Pack) Cath</td>\n",
       "      <td>3473</td>\n",
       "      <td>787740.68</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21020000880</th>\n",
       "      <td>Coloplast SpeediCath Male Size 10-14 (30-Pack) Cath</td>\n",
       "      <td>4260</td>\n",
       "      <td>780975.01</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21020001408</th>\n",
       "      <td>LoFric Origo+Water Nelaton Male 40cm Size 10-18(30-Pack)Cath</td>\n",
       "      <td>3767</td>\n",
       "      <td>646156.02</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21020001195</th>\n",
       "      <td>Coloplast SpeediCath Compact Plus Fle 10-14 (30-Pack) Cath</td>\n",
       "      <td>2755</td>\n",
       "      <td>610643.90</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21020001254</th>\n",
       "      <td>LoFric Sense Nelaton Fle 15cm 8-14 (30-Pack) Cath Wellspect</td>\n",
       "      <td>2726</td>\n",
       "      <td>550377.45</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0702010F0AAACAC</th>\n",
       "      <td>Estriol_Crm 0.01% + Applic</td>\n",
       "      <td>19028</td>\n",
       "      <td>546255.35</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                                                                         name  \\\n",
       "bnf_code                                                                        \n",
       "21300000111      Hylo-Forte Sod Hyaluronate Eye Dps 0.2% P/F 10ml               \n",
       "21020001196      Coloplast SpeediCath Compact Male OneSize 12/18(30-Pack)Cath   \n",
       "0301020S0BBAAAA  Seebri_Breezhaler Inh Cap 55mcg + Dev                          \n",
       "190700000BBCJA0  Resource_ThickenUp Clr Pdr                                     \n",
       "21020001190      Coloplast SpeediCath Compact Fle Size 8-14 (30-Pack) Cath      \n",
       "21020000880      Coloplast SpeediCath Male Size 10-14 (30-Pack) Cath            \n",
       "21020001408      LoFric Origo+Water Nelaton Male 40cm Size 10-18(30-Pack)Cath   \n",
       "21020001195      Coloplast SpeediCath Compact Plus Fle 10-14 (30-Pack) Cath     \n",
       "21020001254      LoFric Sense Nelaton Fle 15cm 8-14 (30-Pack) Cath Wellspect    \n",
       "0702010F0AAACAC  Estriol_Crm 0.01% + Applic                                     \n",
       "\n",
       "                 items    net_cost  \n",
       "bnf_code                            \n",
       "21300000111      82955  1033619.00  \n",
       "21020001196      4624   1014858.96  \n",
       "0301020S0BBAAAA  29304  921215.28   \n",
       "190700000BBCJA0  18710  854096.22   \n",
       "21020001190      3473   787740.68   \n",
       "21020000880      4260   780975.01   \n",
       "21020001408      3767   646156.02   \n",
       "21020001195      2755   610643.90   \n",
       "21020001254      2726   550377.45   \n",
       "0702010F0AAACAC  19028  546255.35   "
      ]
     },
     "execution_count": 43,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df2.sort_values(['net_cost'], ascending=False).head(10)"
   ]
  }
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