format-version: 1.2 data-version: releases/2020-05-22 subsetdef: efo_slim "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: upper_level "" ontology: ecao property_value: http://purl.org/dc/elements/1.1/description "None" xsd:string property_value: http://purl.org/dc/elements/1.1/title "Echinoderm Anatomy and Development Ontology" xsd:string property_value: http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/3.0/ [Term] id: BFO:0000001 name: entity property_value: BFO:0000179 "entity" xsd:string property_value: BFO:0000180 "Entity" xsd:string property_value: IAO:0000112 "Julius Caesar" xsd:string property_value: IAO:0000112 "the Second World War" xsd:string property_value: IAO:0000112 "Verdi’s Requiem" xsd:string property_value: IAO:0000112 "your body mass index" xsd:string property_value: IAO:0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string property_value: IAO:0000116 "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", http://www.w3.org/2000/01/rdf-schema#seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"} property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000002 name: continuant def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." [] is_a: BFO:0000001 ! entity disjoint_from: BFO:0000003 ! occurrent relationship: part_of BFO:0000002 ! continuant property_value: BFO:0000179 "continuant" xsd:string property_value: BFO:0000180 "Continuant" xsd:string property_value: IAO:0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string property_value: IAO:0000116 "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"} property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000003 name: occurrent def: "An entity that has temporal parts and that happens, unfolds or develops through time." [] relationship: part_of BFO:0000003 ! occurrent [Term] id: BFO:0000004 name: independent continuant def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." [] def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} is_a: BFO:0000002 ! continuant relationship: part_of BFO:0000004 ! independent continuant property_value: BFO:0000179 "ic" xsd:string property_value: BFO:0000180 "IndependentContinuant" xsd:string property_value: IAO:0000112 "a chair" xsd:string property_value: IAO:0000112 "a heart" xsd:string property_value: IAO:0000112 "a leg" xsd:string property_value: IAO:0000112 "a molecule" xsd:string property_value: IAO:0000112 "a spatial region" xsd:string property_value: IAO:0000112 "an atom" xsd:string property_value: IAO:0000112 "an orchestra." xsd:string property_value: IAO:0000112 "an organism" xsd:string property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string property_value: IAO:0000112 "the interior of your mouth" xsd:string property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000015 name: process def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." [] is_a: BFO:0000003 ! occurrent [Term] id: BFO:0000040 name: material entity def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." [] is_a: BFO:0000004 ! independent continuant disjoint_from: BFO:0000141 ! immaterial entity property_value: BFO:0000179 "material" xsd:string property_value: BFO:0000180 "MaterialEntity" xsd:string property_value: IAO:0000112 "a flame" xsd:string property_value: IAO:0000112 "a forest fire" xsd:string property_value: IAO:0000112 "a human being" xsd:string property_value: IAO:0000112 "a hurricane" xsd:string property_value: IAO:0000112 "a photon" xsd:string property_value: IAO:0000112 "a puff of smoke" xsd:string property_value: IAO:0000112 "a sea wave" xsd:string property_value: IAO:0000112 "a tornado" xsd:string property_value: IAO:0000112 "an aggregate of human beings." xsd:string property_value: IAO:0000112 "an energy wave" xsd:string property_value: IAO:0000112 "an epidemic" xsd:string property_value: IAO:0000112 "the undetached arm of a human being" xsd:string property_value: IAO:0000116 "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string property_value: IAO:0000116 "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string property_value: IAO:0000116 "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000141 name: immaterial entity is_a: BFO:0000004 ! independent continuant [Term] id: CARO:0000000 name: anatomical entity is_a: CARO:0030000 ! biological entity property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl [Term] id: CARO:0000006 name: material anatomical entity is_a: BFO:0000040 ! material entity is_a: CARO:0000000 ! anatomical entity property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl [Term] id: CARO:0000007 name: immaterial anatomical entity is_a: BFO:0000141 ! immaterial entity [Term] id: CARO:0030000 name: biological entity is_a: BFO:0000004 ! independent continuant [Term] id: ECAO:00000000 name: root node [Term] id: ECAO:0000010 name: life cycle period [Term] id: ECAO:0000020 name: gametogenesis def: "Biological process during which certain cells of a female or male individual (parent) are transformed into specialized reproductive cells (gametes) that will initiate development of a progeny individual (offspring) upon fertilization." [] is_a: UBERON:0000105 ! life cycle stage relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000030 name: oogenesis period def: "Period during which female gametes (or oocytes, or eggs) develop and mature from primordial female germ cells to generate cells competent to further development upon fertilization by a mature spermatozoid." [] synonym: "ovogenesis period" EXACT [] relationship: part_of ECAO:0000020 ! gametogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000040 name: previtellogenic primary oocyte stage def: "A female gamete that is small in size, i.e. about 10??m in diameter, and that is at the previtellogenic stage." [] relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000050 name: not fully grown oocyte stage def: "A developing female gamete that started growing in size by accumulation of yolk proteins. At this stage, it is characterized by the presence of a large nucleus, the germinal vesicle, which contains a prominent nucleolus and occupies most of the cytoplasm." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000040 ! previtellogenic primary oocyte stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000060 name: fully grown oocyte with centered germinal vesicle stage def: "A developing female gamete that has reached its full size. It has grown up to ten times its original size, i.e. 80 to 100??m. It also displays a large germinal vesicle that is centered, but it is still not competent for fertilization." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000050 ! not fully grown oocyte stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000070 name: fully grown oocyte with off-centered germinal vesicle stage def: "A developing female gamete that has reached its full size and in which the germinal vesicle has moved asymmetrically to the cell periphery. The germinal vesicle is now close to the animal pole." [] synonym: "primary oocyte" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000080 name: fully grown oocyte with no nucleus stage def: "A developing female gamete in which the germinal vesicle has broken down. The germinal vesicle is no longer visible. However, the female gamete is still not mature. It is undergoing meiotic maturation, extruding successively a first and a second polar body." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000090 name: mature oocyte stage def: "A mature female gamete that has achieved its meiotic maturation and in which the female pronucleus is visible. The mature oocyte is arrested in G1 phase and its average size is 80 to 100 µm. It is surrounded by a transparent jelly coat that is about 30 µm thick. It is competent to fertilization and it is located in the female gonad where it may be stored for weeks to months before its release in sea water by spawning. In the P. lividus species, the mature female gametes are characterized by the presence of pigment granules concentrated in a subequatorial band. This band is classically called the pigment band and allows to visualize the first embryonic axis, i.e. the animal-vegetal axis, which is perpendicular to the band." [] synonym: " spawned egg" EXACT [] synonym: "unfertilized egg" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000080 ! fully grown oocyte with no nucleus stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000100 name: spermatogenesis period def: "Period during which male gametes (or spermatozoa, or spermatozoid) develop and mature from primordial male germ cells to generate cells competent to further development upon fertilization of a mature oocyte." [] relationship: part_of ECAO:0000020 ! gametogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000110 name: developing spermatozoa stage def: "A developing, immature male gamete undergoing mitosis and meiosis to ultimately produce mature spermatozoa." [] synonym: "spermatid" EXACT [] relationship: part_of ECAO:0000100 ! spermatogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000120 name: mature spermatozoid stage def: "A mature male gamete that is composed of a head, encompassing a compact nucleus, a neck, a middle piece, and a tail (or flagellum) that propels it towards the oocyte upon spawning." [] synonym: " spermatozoa" EXACT [] synonym: "sperm" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000110 ! developing spermatozoa stage relationship: part_of ECAO:0000100 ! spermatogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000130 name: embryogenesis def: "Biological process during which the embryo forms. This process starts with the fertilization of a mature oocyte by a mature spermatozoid. It is characterized by a succession of rapid mitotic divisions with no significant growth, but with axis establishment and cellular differentiation, thereby leading to the development of a multicellular embryo." [] is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by ECAO:0000020 ! gametogenesis relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000140 name: 1-cell stage def: "A fertilized egg, right after fertilization. The embryo is characterized morphologically by the fact that it is a single diploid cell surrounded by a fertilization envelope. This stage corresponds to an embryo of age 0 hour post-fertilization." [] synonym: " fertilized egg" EXACT [] synonym: "zygote stage" EXACT [] xref: UBERON:0000106 is_a: BFO:0000003 ! occurrent relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000150 name: cleavage period def: "Period during which the fertilized egg undergoes a succession of rapid cell divisions with no significant growth." [] xref: UBERON:0000107 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000160 name: 2-cell stage def: "An embryo that is composed of two cells and is surrounded by a fertilization envelope. The first cleavage plane took place meridionally (i.e. along the animal-vegetal axis), thereby generating two blastomeres of equal size, each containing both animal and vegetal cytoplasm. " [] synonym: "2c" EXACT [] xref: UBERON:0007232 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000170 name: 4-cell stage def: "An embryo that is composed of four cells and is surrounded by a fertilization envelope. The second cleavage plane was meridional and perpendicular to the first one, thereby producing four blastomeres of equal size, each containing both animal and vegetal cytoplasm. " [] synonym: "4c" EXACT [] xref: UBERON:0007233 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000160 ! 2-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000180 name: 8-cell stage def: "An embryo that is composed of eight cells and is surrounded by a fertilization envelope. The third cleavage took place perpendicular to the first two cleavage planes and was equatorial. It thus generated an animal and a vegetal hemisphere each composed of a quartet of four cells of equal volume." [] synonym: "8c" EXACT [] xref: UBERON:0007236 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000170 ! 4-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000190 name: 16-cell stage def: "An embryo that is composed of 16 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: although the fourth cleavage occurred simultaneously in all cells, the pattern of cell division differed in the animal and vegetal blastomeres. In the animal hemisphere the four cells divided meridionally, producing eight blastomeres of equal volume arrayed in a single tier. These cells are called the mesomeres. In the vegetal hemisphere, the four cells underwent an unequal, equatorial cleavage, producing a tier of four large cells, the macromeres, and a tier of four small cells, the micromeres, located at the vegetal pole. At the 16-cell stage, the embryo is hence composed of three groups of cells with distinct sizes. In most sea urchin species,this is the first morphological indication of the animal-vegetal axis. " [] synonym: "16c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000180 ! 8-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000200 name: 28-cell stage def: "An embryo that is composed of 28 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: In most sea urchin species, the fifth cleavage signed the end of cell division synchrony, with the mesomeres and macromeres dividing prior to the micromeres with a significant time difference. In the animal hemisphere, the mesomeres underwent an equal and equatorial cleavage, giving rise to two animal cell tiers, each composed of eight blastomeres of equal size: the an1 tier located at the animal pole and the an2 tier located below an1. In parallel, the macromeres divided meridionally, forming a ring of eight cells of equal volume located below the an2 tier. At that stage, the micromeres have not yet divided and are still at a number of four cells." [] synonym: "28c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000210 name: 32-cell stage def: "An embryo that is composed of 32 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: The micromeres have undergone a fifth cleavage (and this has occurred prior to a subsequent division of the other cells). This cleavage was unequal and equatorial, thereby producing four large micromeres and four small micromeres, the smallest cells still marking the vegetal pole." [] synonym: "32c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000220 name: 56-cell stage def: "An embryo that is composed of 56 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: In the animal hemisphere, cells of the an1 and an2 tiers underwent an additional meridional division, producing tiers composed of 16 cells. The macromeres divided equatorially and equally, generating two vegetal cell tiers, each composed of 8 cells of equal volume, namely the veg1 tier (located below an2) and the veg2 tier (located below veg1 and above the large micromeres). At that stage, the large and small micromeres (4 cells each) have not undergone yet a sixth division." [] synonym: "56c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000230 name: 60-cell stage def: "An embryo that is composed of 60 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: The large micromeres have achieved a sixth cleavage, which was meridional, thereby generating a ring of 8 cells. At that stage, from the animal to the vegetal pole, the embryo is composed of: 16 an1-cells, 16 an2-cells, 8 veg1-cells, 8 veg2-cells, 8 large micromeres and 4 small micromeres. " [] synonym: "60c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000220 ! 56-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000240 name: blastula period def: "Period during which the embryo is transformed into a hollow sphere that is one cell layer thick and encompasses a central, fluid-filled cavity called the blastocoel. During this period, every cell of the embryo is in contact on the inside with the blastocoel and on the outside with the hyaline layer." [] xref: UBERON:0000307 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000150 ! cleavage period relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000250 name: very early blastula stage def: "The embryo is composed of 110-120 cells, as most blastomeres have completed an additional mitotic division after the 60-cell stage. The embryo is surrounded by a fertilization envelope. All cells are about the same size and there are no obvious morphological indications of embryonic polarity or embryonic territories. All cells have begun to acquire apico-basal polarity, and the embryo is beginning to transform into a hollow sphere with a wall that is one cell layer thick and a fluid-filled cavity (the blastocoel) in the center. Note for euechinoid indirect developers: the micromere progeny divide more slowly than other cells of the embryo. Molecular labelling typically indicates the presence of 8 large micromere descendants and 4 small micromeres at this stage ." [] synonym: " 120-cell stage" EXACT [] synonym: " B1" EXACT [] synonym: "vEB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000260 name: early blastula stage def: "The embryo is composed of slightly more than 200 cells, as most blastomeres have completed an additional mitotic division after the very early blastula stage. The embryo is surrounded by a fertilization envelope. The embryo remains spherical and one cell layer thick, and the blastocoel has expanded slightly since the very early blastula stage, without increasing though the size of the embryo. The synchrony of cell divisions between animal and vegetal cell tiers, as well as within cell tiers, is becoming less pronounced. Note for euechinoid indirect developers: Molecular labeling typically indicates the presence of 16 large micromere descendants and 4 small micromeres at this stage ." [] synonym: " B2" EXACT [] synonym: "EB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000250 ! very early blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000270 name: mid-blastula stage def: "The embryo is composed of about 300 cells and is surrounded by a fertilization envelope. Cell divisions are less synchronous than at earlier stages. The cells have flattened slightly on their inner (basal) surface, further contributing to the enlargement of the blastocoel. In some species, cells have started to form cilia on their outer surface. The embryo is still spherical and does not display any obvious morphological landmarks that indicate the primary or secondary embryonic axes. Note for euechinoid indirect developers: molecular labeling typically indicates the presence of 16 to 32 large micromere descendant cells and 4 to 8 small micromere descendants at this stage . " [] synonym: " B3" EXACT [] synonym: " midB" EXACT [] synonym: "mid-B" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000260 ! early blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000280 name: late blastula stage def: "The embryo is composed of about 400 cells and is surrounded by a fertilization envelope. The embryo is still spherical but the wall is thinner and smoother than at previous stages. The vegetal plate has not formed. Many cells are ciliated, and in some species (e.g. P. lividus) the embryo has begun to rotate within the fertilization envelope, while in others (e.g. S. purpuratus) it is still non-motile. Note for euechinoid indirect developers: molecular labeling typically indicates the presence of 32 large micromere descendants and 4 to 8 small micromere descendants at this stage ." [] synonym: " B4" EXACT [] synonym: " LB" EXACT [] synonym: " pre-HB" EXACT [] synonym: " prehatched blastula" EXACT [] synonym: "Late-B" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000290 name: hatched blastula stage def: "The embryo is composed of about 800 cells and is surrounded by a fertilization envelope. The fertilization envelope has started to break down due to the secretion by ectodermal cells of the hatching enzyme, a metalloprotease that digests the fertilization envelope and frees the embryo. The vegetal plate has not formed. The embryo rotates within the envelope or swims away as soon as it is free. At the animal pole, a tuft of long and immotile cilia has started growing." [] synonym: " B5" EXACT [] synonym: " very late blastula stage" EXACT [] synonym: "HB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000300 name: swimming blastula stage def: "The embryo has hatched from the fertilization envelope and swims freely. It is still a hollow sphere that is one cell layer thick, but the cells constituting the vegetal plate (i.e. located at the vegetal pole) have started thickening along the apico-basal axis, thereby creating a morphological landmark that enables orienting the embryo along the animal-vegetal axis. In addition, at the animal pole, the apical tuft composed of long and immotile cilia has continued expending." [] synonym: "SB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000290 ! hatched blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000310 name: late swimming blastula stage def: "The embryo has started elongated along the animal-vegetal axis. Its vegetal region has further continued to thicken and it is marked by a characteristic 'V' shape formed by the blastocoel at the level of the cells constituting the vegetal plate, thereby pointing to the vegetal pole. At the animal pole, the embryo is characterized by the presence of an apical tuft. " [] synonym: "late-SB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000300 ! swimming blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000320 name: gastrula period def: "Period during which complex and coordinated cellular movements take place and ultimately generate a three-layered embryo with inner tissues. A portion of cells will ingress, invaginate and/or migrate within the embryo and form the two inner layers (i.e. the endoderm and the mesoderm). The cells that remained outside will instead spread over the whole surface of the embryo and form the outer layer (i.e. the ectoderm)." [] xref: UBERON:0000109 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000240 ! blastula period relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000330 name: mesenchyme blastula phase def: "The phase during which skeletogenic primary mesenchyme cells (PMCs) move from the vegetal plate into the blastocoel (ingress) but before the vegetal plate has started to invaginate." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000240 ! blastula period relationship: part_of ECAO:0000320 ! gastrula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000340 name: early mesenchyme blastula stage def: "The vegetal plate is apparent and skeletogenic primary mesenchyme cells (PMCs) are in the process of ingression, a type of epithelial–mesenchymal transition (EMT). The epithelial wall of the embryo has thickened at the animal pole, where a tuft of long, non-motile cilia has formed." [] synonym: "eMB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000240 ! blastula period relationship: part_of ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000350 name: mid-mesenchyme blastula stage def: "All skeletogenic primary mesenchyme cells (PMCs) have ingressed into the blastocoel, leaving behind a reformed vegetal plate containing at its center the 8 small micromere descendants surrounded by non-skeletogenic mesoderm cells. The PMCs are organized in a mound on the vegetal plate but have not begun to disperse. The thickened apical pole domain with its tuft of long, non-motile cilia is still apparent." [] synonym: "mid-MB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000360 name: late mesenchyme blastula stage def: "The skeletogenic primary mesenchyme cells (PMCs) have migrated away from the vegetal plate by extending filopodia and moving along the blastocoel wall. The vegetal plate has flattened but has not started to invaginate. The apical pole domain still bears an apical tuft of long, non-motile cilia. " [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000350 ! mid-mesenchyme blastula stage relationship: part_of ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000370 name: invagination phase def: "Period during which the inpocketing and elongation of the archenteron takes place." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0000320 ! gastrula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000380 name: blastopore formation stage def: "The embryo is characterized morphologically by a slight invagination of the vegetal plate and the dispersal of the skeletogenic primary mesenchyme cells (PMCs) along the blastocoel wall at the periphery of the invaginating region. The PMCs are just beginning to adopt a characteristic, ring-like arrangement near the equator of the embryo. Within the vegetal plate, the peripheral non-skeletogenic mesoderm cells have started to indent, undergoing important cell shape changes, but the center of the vegetal plate (composed of small micromeres) has not started to elevate. Invagination has generated the blastopore (an opening that will give rise to the larval anus) as well as the anterior portion of the archenteron (a region that will give rise to the coelomic pouches). At the animal pole, the apical pole domain is still marked by an enlarged epithelium bearing long and immotile cilia." [] synonym: " blastopore gastrula stage" EXACT [] synonym: "blasto-G" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000360 ! late mesenchyme blastula stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000390 name: early gastrula stage def: "The embryo is mainly characterized morphologically by the presence in the blastocoel of a small archenteron (i.e. primitive digestive tract) that is about a third of its finally size. Following the initial invagination of the vegetal plate, the archenteron has slightly been extended, within the blastocoel, by the subsequent invagination of additional non-skeletogenic mesoderm cells and of some endoderm cells. In parallel, the skeletogenic mesenchyme cells (or SM cells, primary mesenchyme cells or PMC) have by now started migrating along the blastocoel wall, towards the animal pole, thereby creating two lateral chains (one left and one right), while around the developing archenteron, they have gathered into two ventrolateral clusters separated by an oral (or ventral) and an aboral (or dorsal) chain defined by the remaining skeletogenic mesenchyme cells. Within the oral and aboral skeletogenic mesenchyme chains, the cells have further started to fuse to form syncytial filopodial cables within which skeletal calcification will subsequently take place. At the animal pole, the animal neuroectoderm territory is still marked by an enlarged epithelium bearing long and immotile cilia. " [] synonym: " EG" EXACT [] synonym: "eG" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000400 name: mid-gastrula stage def: "The embryo is mainly characterized morphologically by the presence of an archenteron (i.e. primitive digestive tract) that has reached one-half its way into the blastocoel. A second phase of archenteron elongation has taken place by invagination of additional cells into the blastocoel, by cell division or by convergent-extension movements depending on the sea urchin species. Non-skeletogenic mesoderm cells that are present at the tip of the archenteron have further started ingressing into the blastocoel, generating the non-skeletogenic mesenchyme cells (or NSM cells, secondary mesenchyme cells or SMC). The oral ectoderm has also started to flatten and to become thicker, providing the first morphological indicator of the oral-aboral (or ventro-dorsal) axis of the embryo. As a consequence the oral chain formed by a portion of the skeletogenic mesenchyme cells has also flattened. Finally, skeletal calcification has further begun within the skeletogenic mesenchyme ventrolateral clusters, marked by the presence of the first calcified structures, which appear as small dots at that stage. At the animal pole, the animal neuroectoderm territory is still marked by an enlarged epithelium bearing long and immotile cilia." [] synonym: " mid-G" EXACT [] synonym: "G" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000410 name: late gastrula stage def: "The embryo is mainly characterized morphologically by the presence in the blastocoel of a fully extended archenteron (i.e. primitive digestive tract) that has now reached the roof of the blastocoel. The third and last extension phase of the archenteron has been ensured by pulling forces exerted by non-skeletogenic mesoderm cells that are still present at the tip of the archenteron. These cells have produced filopodia that extended towards the animal pole, attached the wall, and then shortened, thereby pulling up the archenteron. In some sea urchin species, this pulling force is already orienting the tip of the archenteron towards the oral ectoderm, where the future mouth of the larvae will form. In parallel, in the blastocoel, additional non-skeletogenic mesoderm cells continued ingressing from the tip of the archenteron and the skeletal calcified structures present in the skeletogenic mesenchyme ventrolateral clusters have further grown, forming now the primary triradiate skeletal rudiments (or spicules). At the animal pole, the animal neuroectoderm territory is still marked by an enlarged epithelium bearing long and immotile cilia." [] synonym: " late-G" EXACT [] synonym: "LG" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000420 name: organogenesis period def: "To be written" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000320 ! gastrula period relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000430 name: prism stage def: "The embryo is mainly characterized morphologically by a typical triangular shape, the beginning of the tripatition of the digestive tract and the presence of pigmented cells. The oral (or ventral) ectoderm has by now even more flattened, making an almost perfect right angle with the blastoporal side of the embryo. By contrast, on the opposite side, the aboral (or dorsal) ectoderm has round up and slightly elongated, thereby forming the primitive apex of the future larvae. These changes have conferred the embryo a typical and easy recognizable triangular shape. In the oral ectoderm, a small depression has further appeared, called the stomodeum, which will later fuse with the tip of the archenteron to form the mouth. In the blastocoel, the digestive tract has also by now bended toward the stomodeum and started to become tripartite. The cardiac sphincter has started forming, separating the future esophagus from the future stomach. The triradiate spicules have also continued elongating, thereby forming by now, towards the animal pole, the right and left dorsoventral connecting rods, towards the apex, the body rods, and along the vegetal, oral ectoderm the left and right ventral transverse rods. Moreover, some non-skeletogenic mesenchyme cells (or NSM cells, secondary mesenchyme cells or SMC) have started becoming pigmented and inserted into the aboral ectoderm. These cells represent part of the future immune system of the larvae along with other blastocoelar cells that are present in the blastocoel around the gut. In the vicinity of the future esophagus, other non-skeletogenic mesoderm descendant cells along with some endoderm cells have further arranged to form a single unpaired coelomic pouch. At the animal pole, the apical pole domain has also started to flatten making the embryo look like a square when viewed from the oral side, and it still arbors a tuft a long and immotile cilia. Finally, within the apical pole domain, but not yet in the ciliary band, molecular labeling surveys also start by this stage to reveal the presence of differentiating neuronal cells. " [] synonym: " D" EXACT [] synonym: "Pr" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000440 name: larval development is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000130 ! embryogenesis relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000450 name: early feeding larva period def: "Biological process during which the specific outcome is the progression of a free-living larva before the development of the adult. Indirect development represents the mainstream developmental mode of metazoans. This process usually starts with the emergence of a larva that is planktonic and stops at the end of metamorphosis once the animal assumes adult characters." [] xref: UBERON:0000069 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by ECAO:0000420 ! organogenesis period relationship: part_of ECAO:0000440 ! larval development property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000460 name: early pluteus larva stage def: "The embryo is by now a fully formed pluteus larva. The mouth has opened and the digestive tract is becoming functional. On the ventral side, the mouth is surrounded anteriorly by an oral hood and posteriorly by two postoral arms. On the dorsal side, the apex has lengthened. The skeleton has indeed continued extending, expending the dorsoventral connecting rods, the body rods, and the ventral transverse rods as well as developing the anterolateral rods and the postoral rods. Within the larva, the tripartition of the digestive tract has further progressed. The cardiac sphincter is now fully formed in between the esophagus and the stomach, and the pyloric sphincter in between the stomach and the intestine and the anal sphincter at the level of the anus have also started forming. Around the esophagus, the coelomic pouch has further developed into two bilobed sacs (or pouches), one on each side of the digestive tract. Finally, within the apical pole domain, as well as within the ciliary band, differentiated neurons with their extended axons can also now be distinguished by immunostaining. In parallel, the apical tuft of long and immotile cilia remains discernable at the tip of the oral hood, while in parallel the ciliary band has further started growing a concentrated number of intermediate size motile cilia, which will be used by the larva to swim directionally. " [] synonym: " 2-arm pluteus stage" EXACT [] synonym: " early pluteus stage" EXACT [] synonym: "Eplut" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000430 ! prism stage relationship: part_of ECAO:0000450 ! early feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000470 name: 4-arm pluteus larva stage def: "The 4-arm pluteus larva is mainly characterized morphologically by the presence, on the ventral side, of four extended arms (two anterolateral arms at the level of the oral hood and two postoral arms) and on the dorsal side by a sleeked apex. The larva now possesses a completely tripartite and functional digestive tract composed of an esophagus, a stomach, and an intestine, respectively limited by a cardiac sphincter, a pyloric sphincter, and an anal sphincter. Around the esophagus, the right and left coelomic pouches have further started to grow in size and elongate. The first morphological indicator of a left-right asymmetry becomes apparent at that stage, the left coelomic pouch being slightly more elongated than the right one. Furthermore, a thin protrusion of non-skeletogenic mesenchyme cells can be seen extending from the left coelomic pouch to the anterior ectoderm. This is the primary pore canal, which opens to the exterior environment by the hydropore. The larva further now possesses, all around the esophagus, a network of contractile muscles allowing it to swallow and feed. Finally, the apical tuft previously observed at the animal pole has by now disappeared, leaving behind only the concentrated stretch of intermediate size cilia borne by the ciliary band. " [] synonym: " P" EXACT [] synonym: " Plut" EXACT [] synonym: " Plut4a" EXACT [] synonym: " pluteus larva" EXACT [] synonym: "Pluteus" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0000450 ! early feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000480 name: late feeding larva period def: "To be written" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000450 ! early feeding larva period relationship: part_of ECAO:0000440 ! larval development property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000490 name: 6-arm pluteus larva stage def: "The 6-arm pluteus larva is mainly characterized morphologically by the presence, on the ventral side, of six arms, and by the development, on the anterior midline of the esophagus, of the dorsal arch. The larva has indeed extended on the ventral side two additional posterodorsal arms and has developed on the anterior side an additional skeletal element called the dorsal arch. In addition, at the basis of the postoral and posterodorsal arms, four small patches of ciliary band have by now cut off and migrated toward the apex, forming four patches of ciliated structures called the epaulettes (one posterior and one anterior pair). The nervous system of the larva has also become more complex with cell bodies and axons being present all along the arms and for the latter as well throughout the apex. The left and right coelomic pouches have continued to elongate on each side of the digestive tract. As a note this stage is relatively fleeting. " [] synonym: "Plut6a" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000500 name: 8-arm pluteus larva stage def: "The 8-arm pluteus larva is mainly characterized morphologically by the presence on the ventral side of the larva of eight arms and by the development within the larva, on the left side of the stomach, of the adult rudiment. This stage is relatively long. It includes distinct changes occurring to the larva as well as within the larva, although the larva consistently exhibits 8 arms. In addition, it should be highlighted that the sequence of events taking place at the level of the larva compared to that occurring on the left side of the stomach to form the rudiment are heterochronic, meaning that differences are observed among individuals in the relative timing of these events. From the larval point of view, at that stage, on the anterior side, the dorsal arch has extended out of the oral hood, thereby forming two additional arms above the mouth, i.e. the preoral arms. In parallel, across the apex, the epaulettes have continued developing, thereby generating four large structures rich in cilia and perpendicular to the ventro-dorsal axis. At the tip of the apex, the suture of the body rods has also eventually ruptured, considerably enlarging the larval apex and reducing the angle between the postoral and posterodorsal arms. In parallel, inside the larva, the left coelomic pouch has also by now been partitioned into three parts: the axocoel (upper part, close to the esophagus), the hydrocoel (middle part) and the somatocoel (lower part, next to the stomach). Likewise, on the opposite side, the right coelomic pouch has also been partitioned into a right axohydrocoel and a right somatocoel, although the right axohydrocoel remains in a rudimentary state compared to its left counterparts. In addition, at the basis of the posterodorsal arm on the left side, a small portion of the ectoderm has thickened, invaginated, and came into contact with the left hydocoel. This structure is called the vestibule and together with the left hydrocoel and the left stomatocoel they have further subsequently fused to form the adult rudiment. The formation of the rudiment has overall taken some time, giving rise first to a pentaradial disc and then to a pentaradial complex structure harboring podia (i.e. tube feet) and spines. In parallel, on the right size of the larva, a variable number of pedicellariae (one to four) and endoskeletal elements (i.e. the five genital plates) have further formed, which will also later contribute to the composition of the adult body." [] synonym: "Plut8a" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000510 name: competent pluteus larva stage def: "The competent pluteus larva is mainly characterized morphologically by the presence, on the ventral size, of still 8 arms and by the presence on the left side of the stomach of the rudiment that is now the size of or even bigger than the stomach. The rudiment further harbors by now five long primary podia (i.e. tube feet), five quartets of definitive spines located between the primary podia and five pairs of immature spines at the basis of the primary podia, while on the opposite side, i.e. on the right side of the larva, five to seven immature spines have further developed, supported by the genital plates, along with one to four pedicaellariae. At the level of the larva, in parallel, the anterior and posterior pairs of epaulettes have also considerably increased in size by now and even fused dorsally to the hydropore and to the anus respectively, thereby leaving exempt of cilia two lateral fields in between them. At the center of the left lateral field, the vestibular roof has also by now ruptured and this opening has created the vestibular pore, through which some primary podia of the rudiment protrude outside the larva and scrutinize the substrate looking for the adequate cues to begin metamorphosis. At that stage, the larva is thus exhibiting a typical substrate-test behavior, going to the sea bottom and scrutinizing the substrate. This behavior is characteristic of a larva named competent to metamorphosis, which it will accomplish providing that it is adequately stimulated by environmental factors. " [] synonym: " Cpt8a" EXACT [] synonym: "cPlut" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000520 name: metamorphic larva stage def: "The metamorphic larva stage consists essentially of the evagination of the echinoid rudiment. It is characterized by the execution of conspicuous and relatively abrupt physical changes that take place quite quickly, in about one hour, and during which the planktonic larva is transformed into a benthic juvenile. At that stage, the larva is settled on the substrate and is firmly attached to it by the primary podia of the rudiment. The ectodermal epithelium of its arms has started to collapse, making the spicules supporting the larval arms piercing through the epidermis. The larval mouth and anus have further closed, while in parallel, within the larva, the rudiment spines have lifted up thereby distending the vestibular wall and wide opening the vestibular pore. Following these movements, the rudiment has farther down accomplished and finalized its complete eversion, encapsulating the digestive tract and reaching the right side of the larval body. During this process, the genital plates and the associated pedicellariae and immature spines present on the right side of the larva have further completed the production of the aboral part of the adult body. At the end of metamorphosis, hence at the end of the metamorphic larva stage, the individual has thus become benthic, it is settled in the substrate, and it looks like an adult pentaradial sea urchin although it is smaller in size, deprived of a functional digestive system and sexually immature. " [] synonym: " meta" EXACT [] synonym: "metamorphosis" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000530 name: adulthood def: "Biological process during which changes occur in biological and psychological domains to generate a sexually mature animal." [] is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by ECAO:0000440 ! larval development relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000540 name: juvenile period def: "Period during which a young individual, posing as a small adult, grows but remains unable to reproduce." [] xref: UBERON:0034919 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000520 ! metamorphic larva stage relationship: part_of ECAO:0000530 ! adulthood property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000550 name: early juvenile stage def: "The early juvenile is morphologically similar to both the late rudiment and a miniature sea urchin adult. Like the rudiment, it harbors five primary podia (or tube feet), five quartet of definitive spines, five pairs of immature spines located at the basis of the primary podia, 5 to 7 immature spines supported by the genital plates as well as 1 to 4 pedicellariae. Like the adult, it displays a pentarial symmetry and is settled on the substrate. An early juvenile is about 300 µm in diameter. On its aboral side, it still exhibits some remaining larval rods and tissues, although these will soon disappear. In addition, the plates forming its endoskeleton are still rather light and porous making it looking relatively clear, although it bears lots of red-pigmented cells. However, the postlarva is still deprived of a mouth and an anus, hence of a functional digestive tract. The early juvenile is thus endotrophic, meaning that its growth and development solely relies on energy derived from internal sources. Furthermore, the early juvenile is sexually immature." [] synonym: " endotrophic juvenile" EXACT [] synonym: " postlarva" EXACT [] synonym: "PLJuv" EXACT [] xref: UBERON:0007021 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000520 ! metamorphic larva stage relationship: part_of ECAO:0000540 ! juvenile period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000560 name: late juvenile stage def: "The late juvenile really looks like a small adult. The plates of its endoskeleton have by now densified providing it with a dark shell. In addition, it has finally developed a functional digestive tract. The digestive tract inherited from the larva has indeed by now undergone a complete reorganization, progressively bending within the perivisceral cavity to form two successive loops. The buccal plates and the aristotle lantern have further finished developing, creating a new mouth that has opened on the oral side at the center of the aristotle's lantern, while a new anus has also opened in the periproct, i.e. at the center of the five genital plates. The late juvenile can thus feed and starts growing in size, by grazing on the substrate. The late juvenile is exotrophic, meaning that its growth and development rely on energy derived from external sources. In addition, the primary podia have started to regress by that stage and will eventually disappear, while secondary podia have emerged and are functional, allowing the juvenile to move. Similarly, the immature spines have also started to be lost and be replaced by definitive spines. The genital plate CD has further differentiated into the madreporite and sphaeridia have formed. However, this individual is still sexually immature." [] synonym: "ExJuv" EXACT [] xref: UBERON:0007021 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0000540 ! juvenile period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000570 name: adult period def: "Period during which the animal reaches sexual maturity." [] xref: UBERON:0000066 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000540 ! juvenile period relationship: part_of ECAO:0000530 ! adulthood property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000580 name: adult stage def: "This stage corresponds to a fully formed pentaradial sea urchin that has reached sexual maturity. The gonads have developed within the perivisceral cavity and are connected to the outside by the genital pores pierced into the genital plates. The young adult has grown up to about several centimeters in diameter and is now producing gametes. Time after fertilization is unknown, between several months to one year depending on the sea urchin species and the rate and type of feeding." [] synonym: " gravid sea urchin" EXACT [] synonym: "sexual mature sea urchin" EXACT [] xref: UBERON:0000113 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0000570 ! adult period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000590 name: very late blastula stage def: "The embryo is composed of about 800 cells and is surrounded by a fertilization envelope. The wall of the embryo is thinner and smoother than at previous stages. The vegetal plate has not formed. Many cells are ciliated but the embryo has not begun to rotate within the fertilization envelope. Note for euechinoid indirect developers: molecular labeling typically indicates the presence of 32 large micromere descendants and 4 small micromere descendants at this stage." [] synonym: "vLB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000600 name: vegetal plate stage def: "Stage when the vegetal plate is apparent but primary mesenchyme cells (PMCs) have not started to ingress. Embryos are motile due ciliary beating but have not completed hatching." [] synonym: "VP" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000590 ! very late blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0103500 name: echinoderm anatomy def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [] xref: UBERON:0001062 property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103510 name: anatomical structure def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome" [] xref: UBERON:0000061 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103520 name: anatomical system def: "A system that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity. Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function" [] synonym: " body system" EXACT [] synonym: " connected anatomical system" EXACT [] synonym: "organ system" EXACT [] xref: UBERON:0000467 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103530 name: anatomical region def: "A region of the whole organism without well-defined compartmental boundaries" [] synonym: "organism subdivision" EXACT [] xref: UBERON:0000475 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103540 name: anatomical space xref: UBERON:0000464 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103550 name: whole organism def: "Anatomical structure that is an individual member of a species and consists of one cell or more" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000040 ! previtellogenic primary oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103560 name: multicellular organism def: "Anatomical structure that is an individual member of a species and consists of more than one cell" [] xref: UBERON:0000468 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000160 ! 2-cell stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103570 name: embryo def: "Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems" [] xref: UBERON:0000922 is_a: ECAO:0103560 ! multicellular organism relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103580 name: larva xref: UBERON:0002548 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103560 ! multicellular organism relationship: develops_from ECAO:0103570 ! embryo relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103590 name: juvenile xref: UBERON:0034919 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103560 ! multicellular organism relationship: develops_from ECAO:0103580 ! larva relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103600 name: adult xref: UBERON:0007023 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103560 ! multicellular organism relationship: develops_from ECAO:0103590 ! juvenile relationship: existence_starts_during ECAO:0000580 ! adult stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103610 name: digestive system def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [] xref: UBERON:0001007 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103620 name: embryonic digestive system def: "The gastrointestinal tract that is being formed during embryonic development starting with the formation of the primitive gut tube (or archenteron)" [] is_a: ECAO:0103610 ! digestive system relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103630 name: larval digestive system def: "Organ system responsible for the food uptake and processing in the larva" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103610 ! digestive system relationship: develops_from ECAO:0103620 ! embryonic digestive system relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103640 name: juvenile digestive system is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103610 ! digestive system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103650 name: adult digestive system def: "Anatomical system that processes ingested substances in the adult" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103610 ! digestive system relationship: develops_from ECAO:0103640 ! juvenile digestive system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103660 name: immune system xref: UBERON:0002405 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103670 name: embryonic immune system is_a: ECAO:0103660 ! immune system relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103680 name: larval immune system is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103660 ! immune system relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103690 name: juvenile immune system is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103660 ! immune system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103700 name: adult immune system is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103660 ! immune system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103710 name: reproductive system def: "Anatomical system that has as its parts the organs concerned with reproduction, i.e. the male and female gonads." [] xref: UBERON:0000990 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103720 name: nervous system xref: UBERON:0001016 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103730 name: embryonic nervous system def: "The sum of all the structures in the embryo that will develop into the larval nervous system" [] is_a: ECAO:0103720 ! nervous system relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103740 name: larval nervous system def: "The sum of all the neural structures present in the larva" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103720 ! nervous system relationship: develops_from ECAO:0103730 ! embryonic nervous system relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103750 name: juvenile nervous system is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103720 ! nervous system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103760 name: adult nervous system xref: UBERON:6003559 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103720 ! nervous system relationship: develops_from ECAO:0103750 ! juvenile nervous system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103770 name: muscular system xref: UBERON:0000383 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103780 name: larval muscular system is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103770 ! muscular system relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103790 name: juvenile muscular system is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103770 ! muscular system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103800 name: adult muscular system xref: UBERON:6003218 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103770 ! muscular system relationship: develops_from ECAO:0103790 ! juvenile muscular system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103810 name: endoskeleton def: "Internal support structure of an animal composed of mineralized tissue. It gives shape, support and protection to the body." [] xref: UBERON:0001434 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103820 name: embryonic endoskeleton is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103830 name: larval endoskeleton is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103840 name: rudiment endoskeleton synonym: "skeletal rudiment" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103850 name: juvenile endoskeleton is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103860 name: adult endoskeleton is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103810 ! endoskeleton relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103870 name: water vascular system def: "The water vascular system is a hydraulic system used by sea urchins for locomotion, food and waste transportation, and respiration. The system is composed of canals connecting numerous tube feet. " [] xref: UBERON:0008251 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103880 name: hemal system def: "The hemal system contains the blood. It is composed of a complex network of vessels mainly located around the gut." [] synonym: "haemal system" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103890 name: animal hemisphere def: "Anatomical region that corresponds to the upper half of the embryo, which later is composed of the mesomeres, and ultimately encompasses the presumptive ectoderm" [] synonym: " upper half" EXACT [] synonym: " upper hemisphere" EXACT [] synonym: "animal half" EXACT [] xref: UBERON:0012284 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103900 name: vegetal hemisphere def: "Anatomical region that corresponds to the lower half of the embryo, which later is composed of the macromeres and the micromeres, and ultimately encompasses the endoderm and mesoderm" [] synonym: " lower half" EXACT [] synonym: " lower hemisphere" EXACT [] synonym: "vegetal half" EXACT [] xref: UBERON:0012285 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103910 name: cell cortex is_a: ECAO:0104040 ! cell part relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103920 name: cleavage furrow is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000140 ! 1-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103930 name: animal cortex def: "Cell component comprising the outermost layer of the animal region of the oocyte. It consists of a phospholipid bilayer and associated proteins" [] is_a: ECAO:0103910 ! cell cortex relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103940 name: vegetal cortex def: "Cell component comprising the outermost layer of the vegetal region of the oocyte. It consists of a phospholipid bilayer and associated proteins" [] is_a: ECAO:0103910 ! cell cortex relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103950 name: animal pole def: "The apical region of the animal hemisphere" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103960 name: vegetal pole def: "The apical most region of the vegetal hemisphere. Once cleavages have started the vegetal pole is characterized by the presence of the micromeres initially and then that of the small micromeres" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103970 name: animal pole domain synonym: " animal plate" EXACT [] synonym: " anterior neuroectoderm" EXACT [] synonym: " apical plate" EXACT [] synonym: " neurogenic ectoderm" EXACT [] synonym: "apical pole domain" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103980 name: blastopore xref: UBERON:0000100 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103620 ! embryonic digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103990 name: blastopore lip xref: UBERON:3010455 is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103980 ! blastopore property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104000 name: bottle cell is_a: ECAO:0104010 ! embryonic cell relationship: existence_ends_during ECAO:0000380 ! blastopore formation stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0104020 ! vegetal plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104010 name: embryonic cell is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000160 ! 2-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104020 name: vegetal plate is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000360 ! late mesenchyme blastula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104030 name: cell def: "Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000040 ! previtellogenic primary oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104040 name: cell part def: "Anatomical structure that is part of a cell and that has a granularity level equal to that of a protein complex or higher." [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000040 ! previtellogenic primary oocyte stage relationship: part_of ECAO:0104030 ! cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104050 name: digestive system element def: "Any of the organs or elements that are part of the digestive system" [] xref: UBERON:0013765 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103610 ! digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104060 name: skeletal element xref: UBERON:0004765 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0103810 ! endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104070 name: embryonic structure def: "Any anatomical structure that is part of an embryo" [] xref: UBERON:0002050 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104080 name: larval structure def: "Any anatomical structure that is part of a larva" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104090 name: juvenile structure def: "Any anatomical structure that is part of a juvenile" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104100 name: adult structure def: "Any anatomical structure that is part of an adult" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104110 name: tissue xref: UBERON:0000479 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0103560 ! multicellular organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104120 name: rudiment synonym: " imaginal adult rudiment" EXACT [] synonym: "adult rudiment" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104130 name: rudiment structure is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104140 name: non-rudiment adult structure is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104147 name: intracellular part is_a: ECAO:0104040 ! cell part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104148 name: cytoskeleton is_a: ECAO:0104147 ! intracellular part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104150 name: microtubule is_a: ECAO:0104147 ! intracellular part relationship: part_of ECAO:0104148 ! cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104160 name: nucleus def: "A membrane-bounded organelle of in which chromosomes are housed and replicated. In most cells, it contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some specialized cell types, RNA metabolism or DNA replication may be absent" [] is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104168 name: oocyte def: "A female haploid germ cell." [] is_a: ECAO:0104580 ! gamete relationship: existence_ends_during ECAO:0000030 ! oogenesis period relationship: existence_starts_during ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104170 name: germinal vesicle def: "The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104160 ! nucleus relationship: existence_ends_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: existence_starts_during ECAO:0000050 ! not fully grown oocyte stage relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104180 name: equatorial pigment band def: "The subequatorial accumulation of pigment granules (the so-called ‘pigment band’) in eggs or early stage embryos, which constitutes an unambiguous marker of animal-vegetal polarity" [] synonym: " pigmented band" EXACT [] synonym: "pigment band" EXACT [] is_a: ECAO:0104147 ! intracellular part relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104190 name: cytoplasm def: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures" [] is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000050 ! not fully grown oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104200 name: centrosome is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104210 name: mitotic spindle is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000140 ! 1-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104220 name: meiotic spindle is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104147 ! intracellular part relationship: existence_ends_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104230 name: fertilization envelope def: "A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release" [] synonym: "fertilization membrane" EXACT [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_ends_during ECAO:0000280 ! late blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104247 name: spermatozoid def: "A mature male germ cell" [] synonym: " male gamete" EXACT [] synonym: " mature sperm cell" EXACT [] synonym: " spermatozoa" EXACT [] synonym: " spermatozoan" EXACT [] synonym: "sperm" EXACT [] is_a: ECAO:0104580 ! gamete relationship: existence_ends_during ECAO:0000100 ! spermatogenesis period relationship: existence_starts_during ECAO:0000100 ! spermatogenesis period property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104248 name: aster synonym: " mitotic aster" EXACT [] synonym: "spindle aster" EXACT [] is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0104148 ! cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104250 name: sperm aster synonym: "spermatozoid aster" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104248 ! aster relationship: existence_ends_during ECAO:0000120 ! mature spermatozoid stage relationship: existence_starts_during ECAO:0000120 ! mature spermatozoid stage relationship: part_of ECAO:0104247 ! spermatozoid property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104270 name: acellular membrane xref: UBERON:0005764 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000090 ! mature oocyte stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104280 name: vitelline membrane synonym: " vitelline envelope" EXACT [] synonym: "vitelline layer" EXACT [] xref: UBERON:0003125 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104270 ! acellular membrane relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104300 name: hyaline layer synonym: "hyaline membrane" EXACT [] is_a: ECAO:0104270 ! acellular membrane relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104310 name: microvillus is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104320 name: apical lamina synonym: "fibropellin layer" EXACT [] is_a: ECAO:0104270 ! acellular membrane relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0104300 ! hyaline layer property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104330 name: secretory vesicle is_a: ECAO:0104147 ! intracellular part relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104340 name: cilium is_a: ECAO:0104040 ! cell part relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104350 name: filopodium is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104360 name: basal lamina xref: UBERON:0000482 is_a: ECAO:0104270 ! acellular membrane relationship: existence_ends_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104370 name: basal laminar vesicle synonym: " basal vesicle" EXACT [] synonym: "basal lamina vesicle" EXACT [] is_a: ECAO:0104330 ! secretory vesicle relationship: existence_ends_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104380 name: apical vesicle is_a: ECAO:0104330 ! secretory vesicle relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104390 name: cortical granule synonym: "cortical vesicle" EXACT [] is_a: ECAO:0104330 ! secretory vesicle relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104400 name: echinonectin vesicle synonym: " echinonectin granule" EXACT [] synonym: "nectosome" EXACT [] is_a: ECAO:0104330 ! secretory vesicle relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104410 name: mitochondrion is_a: ECAO:0104147 ! intracellular part relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104420 name: actin cytoskeleton is_a: ECAO:0104148 ! cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104430 name: actin filament synonym: " F-actin filament" EXACT [] synonym: "microfilament" EXACT [] is_a: ECAO:0104147 ! intracellular part relationship: part_of ECAO:0104420 ! actin cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104440 name: nuclear part is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0104160 ! nucleus property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104450 name: nucleoplasm is_a: ECAO:0104440 ! nuclear part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104460 name: nuclear envelope is_a: ECAO:0104440 ! nuclear part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104470 name: endoplasmic reticulum is_a: ECAO:0104147 ! intracellular part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104480 name: spermatozoid entry point is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104490 name: plasma membrane synonym: "cell membrane" EXACT [] is_a: ECAO:0104040 ! cell part relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104500 name: polar body def: "A small cell formed by the meiotic division of an oocyte" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000080 ! fully grown oocyte with no nucleus stage relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104510 name: spermatozoid part synonym: "sperm part" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000100 ! spermatogenesis period relationship: existence_starts_during ECAO:0000100 ! spermatogenesis period relationship: part_of ECAO:0104247 ! spermatozoid property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104520 name: spermatozoid head def: "The part of the late spermatid or spermatozoon that contains the nucleus and acrosome." [] is_a: ECAO:0104510 ! spermatozoid part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104530 name: spermatozoid flagellum def: "A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid" [] synonym: "sperm tail" EXACT [] is_a: ECAO:0104510 ! spermatozoid part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104540 name: acrosomal vesicle def: "An organelle that develops over the anterior half of the head in the spermatozoa" [] synonym: "acrosome" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104330 ! secretory vesicle relationship: existence_ends_during ECAO:0000100 ! spermatogenesis period relationship: existence_starts_during ECAO:0000100 ! spermatogenesis period relationship: part_of ECAO:0104520 ! spermatozoid head property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104548 name: small micromere descendant cell synonym: "presumptive primordial germ cell" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104630 ! blastomere relationship: develops_from ECAO:0104720 ! small micromere relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104550 name: presumptive primordial germ cell is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0104548 ! small micromere descendant cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104560 name: primordial germ cell is_a: ECAO:0104030 ! cell relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103710 ! reproductive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104570 name: germ cell is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0104560 ! primordial germ cell relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103710 ! reproductive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104580 name: gamete is_a: ECAO:0104570 ! germ cell relationship: existence_ends_during ECAO:0000020 ! gametogenesis relationship: existence_starts_during ECAO:0000020 ! gametogenesis property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104600 name: immature occyte synonym: "immature egg" EXACT [] is_a: ECAO:0104168 ! oocyte relationship: existence_ends_during ECAO:0000080 ! fully grown oocyte with no nucleus stage relationship: part_of ECAO:0104560 ! primordial germ cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104610 name: mature oocyte def: "A mature female gamet that has entered meiosis." [] synonym: " female gamete" EXACT [] synonym: " female germ cell" EXACT [] synonym: " unfertilized egg" EXACT [] synonym: "egg" EXACT [] is_a: ECAO:0104168 ! oocyte relationship: develops_from ECAO:0104600 ! immature occyte relationship: existence_ends_during ECAO:0000090 ! mature oocyte stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0104570 ! germ cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104630 name: blastomere def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)" [] synonym: "blastoderm cell" EXACT [] is_a: ECAO:0104010 ! embryonic cell relationship: existence_ends_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104640 name: blastomere of 2-cell embryo is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000160 ! 2-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104650 name: blastomere of 4-cell embryo is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000170 ! 4-cell stage relationship: existence_starts_during ECAO:0000170 ! 4-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104660 name: mesomere def: "Intermediate size blastomere forming the animal hemisphere of the cleaving embryo" [] synonym: "mesomeres" EXACT [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000190 ! 16-cell stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104670 name: macromere def: "Larger blastomere of the vegetal hemisphere of the cleaving embryo located below the equator" [] synonym: "macromeres" EXACT [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000190 ! 16-cell stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104678 name: cell tier synonym: "blastomere tier" EXACT [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_ends_during ECAO:0000280 ! late blastula stage relationship: existence_starts_during ECAO:0000180 ! 8-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104680 name: macromere daughter cell tier is_a: ECAO:0104678 ! cell tier relationship: existence_ends_during ECAO:0000210 ! 32-cell stage relationship: existence_starts_during ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104690 name: micromere def: "Small blastomere of the vegetal hemisphere of the cleaving embryo located at to the vegetal pole" [] synonym: "micromeres" EXACT [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000200 ! 28-cell stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104700 name: large micromere is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104630 ! blastomere relationship: develops_from ECAO:0104690 ! micromere relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104710 name: large micromere descendant cell synonym: " presumptive PMC" EXACT [] synonym: " presumptive primary mesenchyme cell" EXACT [] synonym: " presumptive skeletogenic mesenchyme cell" EXACT [] synonym: "large micromere progeny" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104630 ! blastomere relationship: develops_from ECAO:0104700 ! large micromere relationship: existence_ends_during ECAO:0000340 ! early mesenchyme blastula stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104720 name: small micromere synonym: "SM" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104630 ! blastomere relationship: develops_from ECAO:0104690 ! micromere relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104740 name: presumptive neuron def: "A progenitor cell of the nervous system that will develop into a neuron" [] synonym: "neuronal progenitor cell" EXACT [] is_a: ECAO:0104030 ! cell relationship: existence_starts_during ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0103720 ! nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104750 name: animal pole domain presumptive neuron synonym: " animal pole domain neuronal progenitor cell" EXACT [] synonym: "apical pole domain presumptive neuron" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104760 name: ectoderm presumptive neuron synonym: "ectoderm neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104770 name: ciliary band presumptive neuron synonym: "ciliary band neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104780 name: endoderm associated presumptive neuron synonym: "endoderm associated neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104790 name: neuron synonym: "nerve cell" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0104740 ! presumptive neuron relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103720 ! nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104800 name: larval neuron is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103740 ! larval nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104810 name: serotonergic neuron is_a: ECAO:0104790 ! neuron relationship: develops_from ECAO:0104750 ! animal pole domain presumptive neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104820 name: synaptotagmin-B neuron is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104830 name: dopaminergic neuron is_a: ECAO:0104790 ! neuron relationship: develops_from ECAO:0104760 ! ectoderm presumptive neuron relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104840 name: GABAergic neuron is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104850 name: sensory neuron synonym: "sensory cell" EXACT [] is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104860 name: biopolar neuron is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104870 name: multipolar neuron is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104878 name: neural structure synonym: "neuronal structure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103720 ! nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104880 name: axon tract synonym: " axon bundle" EXACT [] synonym: "axonal tract" EXACT [] xref: UBERON:0001018 is_a: ECAO:0104878 ! neural structure property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104900 name: ciliary band neuron synonym: "peripheral neuron" EXACT [] is_a: ECAO:0104800 ! larval neuron relationship: develops_from ECAO:0104770 ! ciliary band presumptive neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104908 name: ectoderm def: "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." [] xref: UBERON:0000924 is_a: ECAO:0105150 ! germ layer relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104910 name: presumptive ciliary band cell is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0104908 ! ectoderm relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104920 name: endoderm associated neuron is_a: ECAO:0104800 ! larval neuron relationship: develops_from ECAO:0104780 ! endoderm associated presumptive neuron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104930 name: ganglion xref: UBERON:0000045 is_a: ECAO:0104878 ! neural structure property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104940 name: apical ganglion synonym: "apical organ" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104930 ! ganglion relationship: develops_from ECAO:0103970 ! animal pole domain relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103740 ! larval nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104950 name: adult neuron is_a: ECAO:0104790 ! neuron relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104960 name: circumoral nerve ring is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104970 name: enteric nerve plexus synonym: " digestive nerve plexus" EXACT [] synonym: "enteric plexus" EXACT [] xref: UBERON:0000429 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104980 name: radial nerve cord is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104990 name: primary podia associated neuron is_a: ECAO:0104950 ! adult neuron relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105000 name: secondary podia associated neuron is_a: ECAO:0104950 ! adult neuron relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105010 name: definitive spine associated neuron is_a: ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105020 name: pedicellaria associated neuron is_a: ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105030 name: basiepidermal nerve plexus is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105050 name: animal quartet def: "Group of four cells of equal size forming the animal hemisphere of an eight-cell stage embryo" [] is_a: ECAO:0104678 ! cell tier relationship: existence_ends_during ECAO:0000180 ! 8-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105060 name: vegetal quartet def: "Group of four cells of equal size forming the vegetal hemisphere of an eight-cell stage embryo" [] is_a: ECAO:0104678 ! cell tier relationship: existence_ends_during ECAO:0000180 ! 8-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105070 name: animal tier 1 synonym: "an1" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0104660 ! mesomere relationship: existence_ends_during ECAO:0000230 ! 60-cell stage relationship: existence_starts_during ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105080 name: animal tier 2 synonym: "an2" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0104660 ! mesomere relationship: existence_ends_during ECAO:0000230 ! 60-cell stage relationship: existence_starts_during ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105090 name: vegetal tier 1 synonym: " ectoendoderm" EXACT [] synonym: "veg1" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0104670 ! macromere relationship: existence_ends_during ECAO:0000260 ! early blastula stage relationship: existence_starts_during ECAO:0000220 ! 56-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105100 name: vegetal tier 2 synonym: " endomesoderm" EXACT [] synonym: "veg2" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0104670 ! macromere relationship: existence_ends_during ECAO:0000260 ! early blastula stage relationship: existence_starts_during ECAO:0000220 ! 56-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105110 name: vegetal tier 1 upper synonym: " presumptive vegetal ectoderm" EXACT [] synonym: " veg1 upper" EXACT [] synonym: "veg1U" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0105090 ! vegetal tier 1 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105120 name: vegetal tier 1 lower synonym: " veg1 lower" EXACT [] synonym: "veg1L" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0105090 ! vegetal tier 1 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105130 name: vegetal tier 2 upper synonym: " veg2 upper" EXACT [] synonym: "veg2U" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105140 name: vegetal tier 2 lower synonym: " presumptive non-skeletogenic mesoderm" EXACT [] synonym: " veg2 lower" EXACT [] synonym: "veg2L" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104678 ! cell tier relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105150 name: germ layer synonym: " embryonic germ layer" EXACT [] synonym: "primary germ layer" EXACT [] xref: UBERON:0000923 is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105158 name: embryonic tissue xref: UBERON:0005291 is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105160 name: presumptive ectoderm xref: UBERON:0006601 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105158 ! embryonic tissue relationship: develops_from ECAO:0104660 ! mesomere relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105180 name: animal ectoderm is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105190 name: vegetal ectoderm is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0103900 ! vegetal hemisphere relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000260 ! early blastula stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105200 name: ventral ectoderm synonym: "oral ectoderm" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105210 name: dorsal ectoderm synonym: "aboral ectoderm" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105220 name: ectoendoderm synonym: " veg1" EXACT [] synonym: "vegetal tier 1" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105150 ! germ layer relationship: develops_from ECAO:0105090 ! vegetal tier 1 relationship: existence_ends_during ECAO:0000590 ! very late blastula stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105230 name: endomesoderm synonym: " mesoendoderm" EXACT [] synonym: " veg2" EXACT [] synonym: "vegetal tier 2" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105150 ! germ layer relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000590 ! very late blastula stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105240 name: inner animal pole domain synonym: "inner apical pole domain" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105250 name: outer animal pole domain synonym: "outer apical pole domain" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105260 name: central ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105270 name: border ectoderm synonym: "BE" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0105220 ! ectoendoderm relationship: existence_ends_during ECAO:0000330 ! mesenchyme blastula phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105280 name: near-apical ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105290 name: apical ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000240 ! blastula period relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105300 name: veg1-lateral ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105310 name: veg-1 oral ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105320 name: lateral ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105330 name: right lateral ectoderm is_a: ECAO:0105320 ! lateral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105340 name: left lateral ectoderm is_a: ECAO:0105320 ! lateral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105350 name: arm tip ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105360 name: dorsal arm tip ectoderm is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0105270 ! border ectoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0105350 ! arm tip ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105370 name: ventral arm tip ectoderm is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0105270 ! border ectoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0105350 ! arm tip ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105380 name: apical tuft is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_starts_during ECAO:0000590 ! very late blastula stage relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105400 name: larval tissue is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105410 name: rudiment tissue is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105420 name: juvenile tissue is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105430 name: adult tissue is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105440 name: presumptive stomodeum is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105200 ! ventral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105450 name: stomodeum synonym: "presumptive mouth" EXACT [] xref: UBERON:0000930 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: develops_from ECAO:0105440 ! presumptive stomodeum relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0105200 ! ventral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105460 name: ciliary band is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105470 name: oral hood ciliary band is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105480 name: arm ciliary band is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105490 name: animal pole ciliary band is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105500 name: vegetal ciliary band is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105510 name: lateral ciliary band is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105520 name: oral hood synonym: " PL" EXACT [] synonym: " preoral lobe" EXACT [] synonym: "oh" EXACT [] is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105530 name: apex is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105540 name: larval arm is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105550 name: right anterolateral arm synonym: " ALA" EXACT [] synonym: "AL" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105560 name: left anterolateral arm synonym: " ALA" EXACT [] synonym: "AL" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105570 name: right postoral arm synonym: "PO" EXACT [] is_a: ECAO:0105540 ! larval arm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105580 name: left postoral arm synonym: "PO" EXACT [] is_a: ECAO:0105540 ! larval arm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105590 name: right posterodorsal arm synonym: "PD" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105600 name: left posterodorsal arm synonym: "PD" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105610 name: right preoral arm synonym: " PRO" EXACT [] synonym: "PR" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105620 name: left preoral arm synonym: " PRO" EXACT [] synonym: "PR" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105628 name: spicule rudiment is_a: ECAO:0104060 ! skeletal element property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105630 name: spicule granule synonym: "spicule dot" EXACT [] is_a: ECAO:0105628 ! spicule rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105650 name: triradiate spicule rudiment synonym: "spicule primordium" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105628 ! spicule rudiment relationship: develops_from ECAO:0105630 ! spicule granule property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105660 name: right ventrolateral triradiate spicule rudiment synonym: "triradiate spicule" EXACT [] is_a: ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000410 ! late gastrula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105670 name: left ventrolateral triradiate spicule rudiment is_a: ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000410 ! late gastrula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105680 name: hexaradiate spicule rudiment synonym: "hexaradiate spicule" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105628 ! spicule rudiment relationship: develops_from ECAO:0105630 ! spicule granule relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105690 name: larval spicule def: "A triradiate or hexaradiate minute calcareous skeletal element that initiates most if not all skeletal structures found within the sea urchin embryo, larva and adult." [] synonym: "primary triradiate skeletal rudiment" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104060 ! skeletal element relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105698 name: embryonic skeletogenic mesenchyme def: "The embryonic tissue made up of loosely connected mesoderm cells that will produce all of the skeletal elements." [] synonym: " primary mesenchyme" EXACT [] synonym: "SM" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: develops_from ECAO:0106220 ! embryonic skeletogenic mesoderm relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105700 name: skeletal rod synonym: "spicule rod" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104060 ! skeletal element relationship: develops_from ECAO:0105698 ! embryonic skeletogenic mesenchyme relationship: existence_ends_during ECAO:0000550 ! early juvenile stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105710 name: anonymous rod is_a: ECAO:0105700 ! skeletal rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105720 name: right anonymous rod is_a: ECAO:0105710 ! anonymous rod relationship: develops_from ECAO:0105660 ! right ventrolateral triradiate spicule rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105730 name: left anonymous rod is_a: ECAO:0105710 ! anonymous rod relationship: develops_from ECAO:0105670 ! left ventrolateral triradiate spicule rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105738 name: right dorsoventral connecting rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105660 ! right ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105740 name: right anterolateral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105738 ! right dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105748 name: left dorsoventral connecting rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105670 ! left ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105750 name: left anterolateral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105748 ! left dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105760 name: right postoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105720 ! right anonymous rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105770 name: left postoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105730 ! left anonymous rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105780 name: right posterodorsal rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105790 name: left posterodorsal rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105798 name: dorsal arch is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104060 ! skeletal element relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105800 name: right preoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105798 ! dorsal arch relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105810 name: left preoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105798 ! dorsal arch relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105850 name: right ventral transverse rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105660 ! right ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105860 name: left ventral transverse rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105670 ! left ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105868 name: posterior tip of body rod is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104060 ! skeletal element relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0105880 ! body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105870 name: scheitel synonym: "body rod end" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104060 ! skeletal element relationship: develops_from ECAO:0105868 ! posterior tip of body rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105880 name: body rod is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104060 ! skeletal element relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105890 name: left body rod is_a: ECAO:0105880 ! body rod relationship: develops_from ECAO:0105730 ! left anonymous rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105900 name: right body rod is_a: ECAO:0105880 ! body rod relationship: develops_from ECAO:0105720 ! right anonymous rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105920 name: posterior tip of left body rod is_a: ECAO:0105868 ! posterior tip of body rod relationship: part_of ECAO:0105890 ! left body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105930 name: posteror tip of right body rod is_a: ECAO:0105868 ! posterior tip of body rod relationship: part_of ECAO:0105900 ! right body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105940 name: right recurrent rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105738 ! right dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105950 name: left recurrent rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105748 ! left dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105960 name: posterior transverse rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105970 name: mouth xref: UBERON:0000165 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105980 name: larval mouth is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105970 ! mouth relationship: develops_from ECAO:0105450 ! stomodeum relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105990 name: anus xref: UBERON:0001245 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106000 name: larval anus is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105990 ! anus relationship: develops_from ECAO:0103980 ! blastopore relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106010 name: presumptive endoderm synonym: "prospective endoderm" EXACT [] xref: UBERON:0006595 is_a: ECAO:0105158 ! embryonic tissue relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000260 ! early blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106020 name: endoderm xref: UBERON:0000925 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105150 ! germ layer relationship: develops_from ECAO:0106010 ! presumptive endoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106030 name: archenteron synonym: " primitive gut" EXACT [] synonym: "embryonic gut" EXACT [] xref: UBERON:0004735 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: develops_from ECAO:0104020 ! vegetal plate relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103610 ! digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106040 name: hindgut xref: UBERON:0001046 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104050 ! digestive system element relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106050 name: dorsal hindgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106060 name: ventral hindgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106070 name: midgut xref: UBERON:0001045 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104050 ! digestive system element relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106080 name: ventral midgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106090 name: dorsal midgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106100 name: anterior midgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106110 name: posterior midgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106120 name: anterior hindgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106130 name: posterior hindgut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106140 name: foregut synonym: "tip of the digestive tract" EXACT [] xref: UBERON:0001041 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104050 ! digestive system element relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106150 name: ventral foregut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106160 name: dorsal foregut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106170 name: anterior foregut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106180 name: posterior foregut is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106190 name: tip of archenteron synonym: "archenteron roof" EXACT [] xref: UBERON:3010432 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: develops_from ECAO:0104020 ! vegetal plate relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106200 name: presumptive mesoderm synonym: "prospective mesoderm" EXACT [] xref: UBERON:0006603 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105158 ! embryonic tissue relationship: develops_from ECAO:0104020 ! vegetal plate relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106210 name: mesoderm xref: UBERON:0000926 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105150 ! germ layer relationship: develops_from ECAO:0106200 ! presumptive mesoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106220 name: embryonic skeletogenic mesoderm def: "The subset of the embryonic mesoderm that will later give rise to the skeletogenic mesenchyme and embryonic skeleton." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105158 ! embryonic tissue relationship: develops_from ECAO:0104700 ! large micromere relationship: existence_ends_during ECAO:0000590 ! very late blastula stage relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0106210 ! mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106240 name: embryonic skeletogenic mesenchyme cell synonym: " primary mesenchyme cell" EXACT [] synonym: "PMC" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0104700 ! large micromere relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0105698 ! embryonic skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106250 name: syncytium synonym: " multinucleated cell" EXACT [] synonym: " syncytial cell" EXACT [] synonym: " syncytium" EXACT [] synonym: "multinucleate cell" EXACT [] is_a: ECAO:0104030 ! cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106260 name: embryonic skeletogenic mesenchyme syncytium def: "Anatomical structure composed of skeletogenic mesenchyme cells that have fused to form a single syncytial network." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0106250 ! syncytium relationship: develops_from ECAO:0105698 ! embryonic skeletogenic mesenchyme relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0103810 ! endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106270 name: subequatorial skeletogenic mesenchyme ring synonym: " PMC ring" EXACT [] synonym: " primary mesenchyme cell ring" EXACT [] synonym: " subequatorial PMC ring" EXACT [] synonym: " subequatorial primary mesenchyme cell ring" EXACT [] synonym: " subequatorial SM ring" EXACT [] synonym: "SM ring" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: develops_from ECAO:0105698 ! embryonic skeletogenic mesenchyme relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106260 ! embryonic skeletogenic mesenchyme syncytium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106280 name: ventral skeletogenic mesenchyme chain def: "Subpopulation of skeletogenic mesenchyme forming a chain on the oral (i.e. ventral) side of the embryo." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106290 name: dorsal skeletogenic mesenchyme chain def: "Subpopulation of skeletogenic mesenchyme forming a chain on the aboral (i.e. dorsal) side of the embryo." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106300 name: right ventrolateral skeletogenic mesenchyme cluster def: "Subpopulation of skeletogenic mesenchyme forming a cluster (i.e. a group of cells) in the ventrolateral region of the embryo." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106310 name: left ventrolateral skeletogenic mesenchyme cluster is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106320 name: lateral chain of skeletogenic mesenchyme def: "Subpopulation of skeletogenic mesenchyme forming a chain on either side of the developing digestive tract, along the blastocoel wall and towards the animal pole." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106260 ! embryonic skeletogenic mesenchyme syncytium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106330 name: right lateral chain of skeletogenic mesenchyme def: "Subpopulation of skeletogenic mesenchyme forming a chain along the blastocoel wall towards the animal pole on the right side of the embryo." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: develops_from ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106320 ! lateral chain of skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106340 name: left lateral chain of skeletogenic mesenchyme def: "Subpopulation of skeletogenic mesenchyme forming a chain along the blastocoel wall towards the animal pole on the left side of the embryo." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104070 ! embryonic structure relationship: develops_from ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106320 ! lateral chain of skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106350 name: embryonic non-skeletogenic mesoderm is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105158 ! embryonic tissue relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000590 ! very late blastula stage relationship: part_of ECAO:0106210 ! mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106360 name: ventral non-skeletogenic mesoderm is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105158 ! embryonic tissue relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106370 name: dorsal non-skeletogenic mesoderm is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105158 ! embryonic tissue relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106380 name: embryonic non-skeletogenic mesenchyme synonym: " NSM" EXACT [] synonym: "secondary mesenchyme" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106390 name: embryonic non-skeletogenic mesenchyme cell synonym: " secondary mesenchyme cell" EXACT [] synonym: "SMC" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0106380 ! embryonic non-skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106400 name: larval non-skeletogenic mesenchyme is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106410 name: larval non-skeletogenic mesenchyme cell is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106400 ! larval non-skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106420 name: presumptive blastocoelar cell is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106430 name: presumptive pigment cell synonym: " presumptive immunocyte" EXACT [] synonym: "presumptive pigmented cell" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106440 name: pigment cell def: "a cell that contains red coloring matter" [] synonym: " pigmented immunocyte" EXACT [] synonym: "pigmented cell" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0106430 ! presumptive pigment cell relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0103660 ! immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106450 name: embryonic pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103670 ! embryonic immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106460 name: larval pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106470 name: juvenile pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103690 ! juvenile immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106480 name: rudiment pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106490 name: blastocoelar cell is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0106420 ! presumptive blastocoelar cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0103660 ! immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106500 name: globular cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106510 name: filopodial cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106520 name: ovoid cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106530 name: amoeboid cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106540 name: muscle precursor cell synonym: "presumptive muscle cell" EXACT [] is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106550 name: muscle is_a: ECAO:0104110 ! tissue relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106560 name: larval muscle synonym: "contractile muscle" EXACT [] is_a: ECAO:0105400 ! larval tissue relationship: part_of ECAO:0103780 ! larval muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106570 name: rudiment muscle is_a: ECAO:0105410 ! rudiment tissue relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106580 name: juvenile muscle is_a: ECAO:0105420 ! juvenile tissue relationship: part_of ECAO:0103790 ! juvenile muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106590 name: adult muscle is_a: ECAO:0105430 ! adult tissue relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103800 ! adult muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106600 name: blastocoel xref: UBERON:0000090 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103540 ! anatomical space relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106610 name: sphincter is_a: ECAO:0104050 ! digestive system element relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106620 name: pyloric sphincter synonym: "midgut-hindgut constriction" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0106610 ! sphincter relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106630 name: cardiac sphincter synonym: "foregut-midgut constriction" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0106610 ! sphincter relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106640 name: anal sphincter synonym: "hindgut-ectoderm constriction" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0106610 ! sphincter relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106650 name: sphincter muscle xref: UBERON:0004590 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0106550 ! muscle relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106660 name: sphincter muscle cell synonym: "myoepithelial cell" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0106650 ! sphincter muscle property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106670 name: pyloric sphincteric muscle synonym: "pyloric sphincter" EXACT [] xref: UBERON:0001202 is_a: ECAO:0106650 ! sphincter muscle relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0106620 ! pyloric sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106680 name: cardiac sphincteric muscle synonym: "cardiac sphincter" EXACT [] is_a: ECAO:0106650 ! sphincter muscle relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0106630 ! cardiac sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106690 name: anal sphincteric muscle synonym: "anal sphincter" EXACT [] xref: UBERON:0004916 is_a: ECAO:0106650 ! sphincter muscle relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0106640 ! anal sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106700 name: larval esophagus is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104050 ! digestive system element relationship: develops_from ECAO:0106140 ! foregut relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106708 name: circumesophageal muscle is_a: ECAO:0106560 ! larval muscle relationship: develops_from ECAO:0106190 ! tip of archenteron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0106700 ! larval esophagus property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106710 name: circumesophageal muscle cell synonym: "presumptive circumesophageal muscle cell" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: develops_from ECAO:0106190 ! tip of archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0106708 ! circumesophageal muscle property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106730 name: larval stomach is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104050 ! digestive system element relationship: develops_from ECAO:0106070 ! midgut relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106740 name: larval intestine is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104050 ! digestive system element relationship: develops_from ECAO:0106040 ! hindgut relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106750 name: larval skeletogenic mesenchyme def: "The mesenchyme cells that produce new skeletal elements (i.e., the posterodorsal rods, dorsal arch, and preoral rods) in the larva after feeding begins" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106760 name: larval skeletogenic mesenchyme cell is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106750 ! larval skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106770 name: coelom xref: UBERON:0011997 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106190 ! tip of archenteron relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106780 name: unpaired coelomic pouch synonym: "unpaired coelomic rudiment" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106790 name: right coelomic pouch is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106800 name: left coelomic pouch synonym: "left coelomic sac" EXACT [] is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106810 name: right coelomic constriction is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106790 ! right coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106820 name: left coelomic constriction is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106800 ! left coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106828 name: larval epithelium is_a: ECAO:0105400 ! larval tissue relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106830 name: vestibule synonym: "amniotic sac" EXACT [] is_a: ECAO:0104080 ! larval structure relationship: develops_from ECAO:0105200 ! ventral ectoderm relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106840 name: oral epithelium synonym: " circumoral ectoderm" EXACT [] synonym: " circumoral epithelium" EXACT [] synonym: "oral epidermis" EXACT [] xref: UBERON:0002424 is_a: ECAO:0105400 ! larval tissue relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106850 name: aboral epithelium is_a: ECAO:0105400 ! larval tissue relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106858 name: left lateral field def: "The left lateral field is the lateral field located on the left side of the larva" [] is_a: ECAO:0107100 ! lateral field property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106860 name: vestibular pore def: "Opening located in the left lateral field" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106858 ! left lateral field relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106868 name: axocoel synonym: "anterior coelom" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106870 name: left axocoel is_a: ECAO:0106868 ! axocoel relationship: develops_from ECAO:0106800 ! left coelomic pouch relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106880 name: axial coelom is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106870 ! left axocoel relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106890 name: hydrocoel synonym: "central coelom" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106910 name: somatocoel synonym: "posterior coelom" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106920 name: left hydrocoel is_a: ECAO:0106890 ! hydrocoel relationship: develops_from ECAO:0106800 ! left coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106930 name: left somatocoel is_a: ECAO:0106910 ! somatocoel relationship: develops_from ECAO:0106800 ! left coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106940 name: right axohydrocoel synonym: "anterior sac" EXACT [] is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106790 ! right coelomic pouch relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106950 name: right somatocoel is_a: ECAO:0106910 ! somatocoel relationship: develops_from ECAO:0106790 ! right coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106958 name: axial complex is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106960 name: stone canal is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106800 ! left coelomic pouch relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106970 name: ring canal is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106920 ! left hydrocoel relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106980 name: radial canal is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106920 ! left hydrocoel relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106990 name: primary pore canal synonym: "hydropore canal" EXACT [] is_a: ECAO:0104080 ! larval structure relationship: develops_from ECAO:0106380 ! embryonic non-skeletogenic mesenchyme relationship: existence_ends_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107000 name: hydropore is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107010 name: right axocoel is_a: ECAO:0106868 ! axocoel relationship: develops_from ECAO:0106940 ! right axohydrocoel property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107020 name: right hydrocoel is_a: ECAO:0106890 ! hydrocoel relationship: develops_from ECAO:0106940 ! right axohydrocoel property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107040 name: axial sinus is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0107020 ! right hydrocoel relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107050 name: axial organ is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107060 name: dorsal sac is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107070 name: ciliated epaulette is_a: ECAO:0104080 ! larval structure relationship: develops_from ECAO:0105460 ! ciliary band relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107080 name: anterior ciliated epaulette is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0107070 ! ciliated epaulette property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107090 name: posterior ciliated epaulette is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0107070 ! ciliated epaulette property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107100 name: lateral field def: "The lateral field is located in the aboral ectoderm of the larva. It separates the anterior and posterior pairs of epaulettes" [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107120 name: right lateral field def: "The right lateral field is the lateral field located on the right side of the larva" [] is_a: ECAO:0107100 ! lateral field property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107140 name: ambulacral plate is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107150 name: adult skeletogenic mesenchyme def: "The mesenchyme cells that produce biomineralized elements (e.g., spines, test plates, and teeth) in the juvenile and adult." [] is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0104110 ! tissue relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107160 name: interambulacral plate synonym: "int" EXACT [] is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107170 name: ambulacra is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107180 name: interambulacra is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107190 name: genital plate is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107200 name: appendage is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107210 name: pedicellaria xref: UBERON:0008261 is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107220 name: ocular plate synonym: "terminal plate" EXACT [] is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107230 name: buccal plate is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107240 name: genital plate AB is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107250 name: genital plate BC is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107260 name: genital plate CD is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107270 name: genital plate DE is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107280 name: genital plate EA is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107290 name: podia synonym: "tube foot" EXACT [] xref: UBERON:0008247 is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107300 name: primary podia synonym: "primary tube foot" EXACT [] is_a: ECAO:0107290 ! podia relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0107200 ! appendage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107310 name: disk of primary podia is_a: ECAO:0104060 ! skeletal element relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0107300 ! primary podia property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107320 name: secondary podia synonym: "secondary tube foot" EXACT [] is_a: ECAO:0107290 ! podia relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107200 ! appendage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107330 name: disk of secondary podia is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107320 ! secondary podia property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107340 name: buccal podia is_a: ECAO:0104990 ! primary podia associated neuron relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107200 ! appendage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107350 name: spine synonym: "spine appendage" EXACT [] xref: UBERON:0008260 is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107360 name: juvenile spine synonym: "splayed spines" EXACT [] is_a: ECAO:0107350 ! spine relationship: existence_ends_during ECAO:0000560 ! late juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107370 name: definitive spine synonym: "adult spine" EXACT [] is_a: ECAO:0107350 ! spine property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107380 name: sphaeridium is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107390 name: ampulla synonym: "tube foot ampulla" EXACT [] xref: UBERON:0008252 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0106980 ! radial canal relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107400 name: adult mouth is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105970 ! mouth relationship: existence_starts_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0103650 ! adult digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107410 name: adult anus is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0105990 ! anus relationship: existence_starts_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0103650 ! adult digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107418 name: Aristotles lantern xref: UBERON:0008253 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103610 ! digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107420 name: tooth is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107418 ! Aristotles lantern property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107440 name: madreporite xref: UBERON:0009476 is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0107190 ! genital plate relationship: develops_from ECAO:0107260 ! genital plate CD relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107450 name: gonopore synonym: "genital pore" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107460 name: gonad xref: UBERON:0000991 is_a: ECAO:0104100 ! adult structure relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103710 ! reproductive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107470 name: ovary xref: UBERON:0000992 is_a: ECAO:0107460 ! gonad property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107480 name: testis xref: UBERON:0000473 is_a: ECAO:0107460 ! gonad property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107490 name: juvenile digestive tract is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103640 ! juvenile digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107510 name: adult digestive tract is_a: CARO:0000000 ! anatomical entity is_a: ECAO:0103510 ! anatomical structure relationship: develops_from ECAO:0103630 ! larval digestive system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103650 ! adult digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107520 name: mesentery xref: UBERON:0002095 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107530 name: perivisceral cavity is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107540 name: photosensory cell synonym: "photoreceptor cell" EXACT [] is_a: ECAO:0104030 ! cell relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: GO:0003674 name: molecular_function is_a: BFO:0000015 ! process property_value: IAO:0000589 "molecular process" xsd:string [Term] id: GO:0003824 name: catalytic activity is_a: GO:0003674 ! molecular_function [Term] id: GO:0008150 name: biological_process is_a: BFO:0000015 ! process [Term] id: GO:0016301 name: kinase activity is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups [Term] id: GO:0016740 name: transferase activity is_a: GO:0003824 ! catalytic activity [Term] id: GO:0016772 name: transferase activity, transferring phosphorus-containing groups is_a: GO:0016740 ! transferase activity [Term] id: UBERON:0000000 name: processual entity namespace: uberon def: "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity] subset: upper_level disjoint_from: UBERON:0001062 ! anatomical entity [Term] id: UBERON:0000066 name: fully formed stage namespace: uberon def: "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "adult stage" BROAD [] synonym: "fully formed animal stage" EXACT [] synonym: "juvenile-adult stage" EXACT [] xref: BilaDO:0000004 xref: BTO:0001043 xref: EFO:0001272 xref: FBdv:00005369 xref: WBls:0000041 xref: XtroDO:0000084 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000092 ! post-embryonic stage relationship: preceded_by UBERON:0000111 ! organogenesis stage relationship: precedes UBERON:0000071 ! death stage property_value: seeAlso https://github.com/obophenotype/uberon/issues/566 [Term] id: UBERON:0000068 name: embryo stage namespace: uberon def: "A life cycle stage that starts with fertilization and ends with the fully formed embryo." [http://orcid.org/0000-0002-6601-2165] synonym: "embryogenesis" RELATED [] synonym: "embryonic stage" EXACT [] xref: BilaDO:0000002 xref: EV:0300001 xref: FBdv:00005289 xref: FMA:72652 xref: HsapDv:0000002 xref: http://www.snomedbrowser.com/Codes/Details/296280003 xref: MmusDv:0000002 xref: OGES:000000 xref: OGES:000022 xref: WBls:0000003 xref: WBls:0000092 xref: WBls:0000102 xref: XAO:1000012 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage disjoint_from: UBERON:0000092 ! post-embryonic stage relationship: precedes UBERON:0000066 ! fully formed stage relationship: precedes UBERON:0000092 ! post-embryonic stage [Term] id: UBERON:0000071 name: death stage namespace: uberon def: "End of the life of an organism." [XAO:0000437] synonym: "death" RELATED [] xref: XAO:0000437 xref: XtroDO:0000085 is_a: UBERON:0000105 ! life cycle stage relationship: ends UBERON:0000104 ! life cycle property_value: UBPROP:0000012 "ncit:Death is an outcome" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0000092 name: post-embryonic stage namespace: uberon def: "stage succeeding embryo, including mature structure" [https://orcid.org/0000-0002-6601-2165] synonym: "post-hatching stage" NARROW [] synonym: "postembryonic" RELATED [] synonym: "postembryonic stage" EXACT [] xref: BilaDO:0000003 xref: OGES:000010 xref: OGES:000014 xref: OGES:000024 xref: WBls:0000022 xref: WBls:0000093 xref: WBls:0000103 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: preceded_by UBERON:0000068 ! embryo stage property_value: seeAlso https://github.com/obophenotype/uberon/issues/344 property_value: UBPROP:0000008 "In birds, the postnatal stage begins when the beak penetrates the shell (i.e., external pipping) (Brown et al. 1997)" xsd:string [Term] id: UBERON:0000104 name: life cycle namespace: uberon def: "An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism." [https://orcid.org/0000-0002-6601-2165] subset: upper_level synonym: "entire life cycle" EXACT [] synonym: "entire lifespan" EXACT [] synonym: "life" EXACT [] synonym: "lifespan" EXACT [] xref: FBdv:00000000 xref: HsapDv:0000001 xref: MmusDv:0000001 xref: ncithesaurus:Life xref: OGES:000011 is_a: UBERON:0000000 ! processual entity relationship: ends_with UBERON:0000071 ! death stage relationship: has_part UBERON:0000105 ! life cycle stage relationship: starts_with UBERON:0000106 ! zygote stage property_value: seeAlso https://github.com/obophenotype/uberon/issues/532 [Term] id: UBERON:0000105 name: life cycle stage namespace: uberon def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: upper_level synonym: "developmental stage" NARROW [] synonym: "stage" NARROW [] xref: BILS:0000105 xref: EFO:0000399 xref: FBdv:00007012 xref: FMA:24120 xref: HsapDv:0000000 xref: MmusDv:0000000 xref: ncithesaurus:Developmental_Stage xref: OlatDv:0000010 xref: PdumDv:0000090 xref: WBls:0000002 xref: XAO:1000000 xref: ZFS:0000000 xref: ZFS:0100000 is_a: UBERON:0000000 ! processual entity relationship: part_of UBERON:0000104 ! life cycle property_value: IAO:0000116 "this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here" xsd:string property_value: UBPROP:0000012 "the WBls class 'all stages' belongs here as it is the superclass of other WBls stages" xsd:string property_value: UBPROP:0000012 "we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage" xsd:string [Term] id: UBERON:0000106 name: zygote stage namespace: uberon def: "A stage at which the organism is a single cell produced by means of sexual reproduction." [http://en.wikipedia.org/wiki/Zygote] subset: efo_slim synonym: "1-cell stage" EXACT [] synonym: "fertilized egg stage" EXACT [BTO:0000854] synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] synonym: "zygotum" RELATED LATIN [http://en.wikipedia.org/wiki/Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 xref: http://en.wikipedia.org/wiki/Zygote xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 xref: XAO:1000001 xref: ZFS:0000001 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: starts UBERON:0000104 ! life cycle property_value: seeAlso EMAPA:16033 property_value: UBPROP:0000003 "As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000745", ontology="VHOG", source="http://bgee.unil.ch/", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.107"} [Term] id: UBERON:0000107 name: cleavage stage namespace: uberon def: "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." [GO:0040016, http://en.wikipedia.org/wiki/Cleavage_(embryo)] subset: efo_slim xref: BilaDO:0000006 xref: BILS:0000107 xref: Cleavage:(embryo) xref: EFO:0001290 xref: FBdv:00000054 xref: MESH:A16.254.270 xref: MmusDv:0000004 xref: OGES:000015 xref: OGES:000020 xref: PdumDv:0000200 xref: XAO:1000004 xref: ZFS:0000046 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by UBERON:0000106 ! zygote stage relationship: part_of UBERON:0000068 ! embryo stage [Term] id: UBERON:0000108 name: blastula stage namespace: uberon def: "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [http://en.wikipedia.org/wiki/Blastula] subset: efo_slim xref: BilaDO:0000007 xref: BILS:0000108 xref: EFO:0001282 xref: HsapDv:0000006 xref: http://en.wikipedia.org/wiki/Blastula xref: MmusDv:0000007 xref: OGES:000003 xref: OGES:000016 xref: OGES:000021 xref: OpenCyc:Mx4rEetFnKP2EdqAAAACs4vPlg xref: WBls:0000005 xref: XAO:1000003 xref: ZFS:0000045 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000107 ! cleavage stage property_value: depicted:by http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png property_value: IAO:0000116 "consider adding a preceding stage 'morula stage' as part of cleavage" xsd:string [Term] id: UBERON:0000109 name: gastrula stage namespace: uberon def: "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GO:0007369] subset: efo_slim synonym: "blastocystis trilaminaris stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastocyst stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastoderm stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar disk stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar stage" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BilaDO:0000008 xref: BILS:0000109 xref: EFO:0001296 xref: FBdv:00005317 xref: HsapDv:0000010 xref: MmusDv:0000013 xref: OGES:000004 xref: OGES:000019 xref: WBls:0000010 xref: XAO:1000005 xref: ZFS:0000047 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000108 {source="BILS"} ! blastula stage [Term] id: UBERON:0000110 name: neurula stage namespace: uberon def: "Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GO:0001841] xref: BilaDO:0000009 xref: BILS:0000110 xref: HsapDv:0000012 xref: MmusDv:0000017 xref: XAO:1000006 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000109 ! gastrula stage property_value: seeAlso https://github.com/obophenotype/uberon/issues/343 [Term] id: UBERON:0000111 name: organogenesis stage namespace: uberon def: "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [http://en.wikipedia.org/wiki/Organogenesis] synonym: "segmentation stage" RELATED [] xref: BilaDO:0000010 xref: BILS:0000111 xref: HsapDv:0000015 xref: http://en.wikipedia.org/wiki/Organogenesis xref: MmusDv:0000018 xref: OGES:000005 xref: OGES:000032 is_a: BFO:0000003 ! occurrent is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000110 ! neurula stage property_value: seeAlso https://github.com/obophenotype/uberon/issues/533 [Term] id: UBERON:0001062 name: anatomical entity namespace: uberon def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [FMA:62955, http://orcid.org/0000-0001-9114-8737] subset: upper_level xref: AAO:0010841 xref: AEO:0000000 xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 xref: FBbt:10000000 xref: FBbt_root:00000000 xref: FMA:62955 xref: HAO:0000000 xref: http://linkedlifedata.com/resource/umls/id/C1515976 xref: MA:0000001 xref: NCIT:C12219 xref: TAO:0100000 xref: TGMA:0001822 xref: UMLS:C1515976 {source="ncithesaurus:Anatomic_Structure_System_or_Substance"} xref: WBbt:0000100 xref: XAO:0000000 xref: ZFA:0100000 [Typedef] id: BFO:0000066 name: occurs in def: "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t" [] comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant property_value: IAO:0000111 "occurs in" xsd:string property_value: IAO:0000118 "occurs_in" xsd:string property_value: IAO:0000118 "unfolds in" xsd:string property_value: IAO:0000118 "unfolds_in" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl domain: BFO:0000003 ! occurrent range: BFO:0000004 ! independent continuant holds_over_chain: part_of BFO:0000066 inverse_of: BFO:0000067 ! contains process transitive_over: part_of ! part of [Typedef] id: BFO:0000067 name: contains process def: "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t" [] comment: Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant property_value: IAO:0000111 "site of" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Typedef] id: RO:0000056 name: participates in def: "a relation between a continuant and a process, in which the continuant is somehow involved in the process" [] property_value: IAO:0000111 "participates in" xsd:string property_value: IAO:0000112 "this blood clot participates in this blood coagulation" xsd:string property_value: IAO:0000112 "this input material (or this output material) participates in this process" xsd:string property_value: IAO:0000112 "this investigator participates in this investigation" xsd:string property_value: IAO:0000118 "participates_in" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000003 ! occurrent inverse_of: RO:0000057 ! has participant [Typedef] id: RO:0000057 name: has participant def: "a relation between a process and a continuant, in which the continuant is somehow involved in the process" [] property_value: http://purl.org/dc/elements/1.1/source http://www.obofoundry.org/ro/#OBO_REL:has_participant xsd:string property_value: IAO:0000111 "has participant" xsd:string property_value: IAO:0000112 "this blood coagulation has participant this blood clot" xsd:string property_value: IAO:0000112 "this investigation has participant this investigator" xsd:string property_value: IAO:0000112 "this process has participant this input material (or this output material)" xsd:string property_value: IAO:0000116 "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time." xsd:string property_value: IAO:0000118 "has_participant" xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000002 ! continuant holds_over_chain: has_part RO:0000057 [Typedef] id: RO:0002013 name: has regulatory component activity def: "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." [] is_a: RO:0002017 ! has component activity is_a: RO:0002334 ! regulated by created_by: dos creation_date: 2017-05-24T09:30:46Z [Typedef] id: RO:0002014 name: has negative regulatory component activity def: "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." [] comment: By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'. is_a: RO:0002013 ! has regulatory component activity is_a: RO:0002335 ! negatively regulated by created_by: dos creation_date: 2017-05-24T09:31:01Z [Typedef] id: RO:0002015 name: has positive regulatory component activity def: "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." [] comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'. is_a: RO:0002013 ! has regulatory component activity is_a: RO:0002336 ! positively regulated by created_by: dos creation_date: 2017-05-24T09:31:17Z [Typedef] id: RO:0002017 name: has component activity comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B. is_a: RO:0002018 ! has component process created_by: dos creation_date: 2017-05-24T09:44:33Z [Typedef] id: RO:0002018 name: has component process def: "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." [] domain: BFO:0000015 ! process range: BFO:0000015 ! process is_a: RO:0002180 ! has component created_by: dos creation_date: 2017-05-24T09:49:21Z [Typedef] id: RO:0002022 name: directly regulated by comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. {xref="GOC:dos"} is_a: RO:0002334 ! regulated by inverse_of: RO:0002578 ! directly regulates created_by: dos creation_date: 2017-09-17T13:52:24Z [Typedef] id: RO:0002023 name: directly negatively regulated by def: "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." [GOC:dos] is_a: RO:0002022 ! directly regulated by inverse_of: RO:0002630 ! directly negatively regulates created_by: dos creation_date: 2017-09-17T13:52:38Z [Typedef] id: RO:0002024 name: directly positively regulated by def: "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." [GOC:dos] is_a: RO:0002022 ! directly regulated by inverse_of: RO:0002629 ! directly positively regulates created_by: dos creation_date: 2017-09-17T13:52:47Z [Typedef] id: RO:0002025 name: has effector activity def: "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity." [GOC:dos] comment: This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations. is_functional: true is_a: RO:0002017 ! has component activity is_a: RO:0002211 ! regulates created_by: dos creation_date: 2017-09-22T14:14:36Z [Typedef] id: RO:0002086 name: ends after comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) subset: ro-eco property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string is_transitive: true is_a: RO:0002222 ! temporally related to [Typedef] id: RO:0002090 name: immediately precedes comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) subset: ro-eco property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000118 "ends_at_start_of" xsd:string property_value: IAO:0000118 "meets" xsd:string property_value: RO:0002575 BFO:0000063 is_a: precedes ! precedes [Typedef] id: RO:0002131 name: overlaps def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" [] subset: ro-eco property_value: IAO:0000114 IAO:0000125 property_value: RO:0001900 RO:0001901 holds_over_chain: has_part part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} holds_over_chain: has_part RO:0002131 holds_over_chain: part_of part_of is_a: RO:0002323 ! mereotopologically related to transitive_over: part_of ! part of expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)" [] [Typedef] id: RO:0002180 name: has component def: "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." [] subset: ro-eco property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity." xsd:string property_value: IAO:0000232 "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit." xsd:string property_value: RO:0001900 RO:0001901 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:Componency is_a: has_part ! has part [Typedef] id: RO:0002211 name: regulates def: "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2." [] property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "David Hill" xsd:string property_value: IAO:0000117 "Tanya Berardini" xsd:string property_value: IAO:0000119 "GO" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Regulation precludes parthood; the regulatory process may not be within the regulated process." xsd:string property_value: IAO:0000589 "regulates (processual)" xsd:string property_value: IAO:0000600 "false" xsd:boolean domain: BFO:0000015 ! process range: BFO:0000015 ! process holds_over_chain: RO:0002578 RO:0002578 is_transitive: true is_a: RO:0002411 ! causally upstream of inverse_of: RO:0002334 ! regulated by [Typedef] id: RO:0002212 name: negatively regulates def: "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "negatively regulates (process to process)" xsd:string property_value: RO:0004050 RO:0002211 is_a: RO:0002211 ! regulates is_a: RO:0002305 ! causally upstream of, negative effect inverse_of: RO:0002335 ! negatively regulated by [Typedef] id: RO:0002213 name: positively regulates def: "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "positively regulates (process to process)" xsd:string property_value: RO:0004049 RO:0002211 holds_over_chain: RO:0002212 RO:0002212 is_transitive: true is_a: RO:0002211 ! regulates is_a: RO:0002304 ! causally upstream of, positive effect inverse_of: RO:0002336 ! positively regulated by [Typedef] id: RO:0002215 name: capable of def: "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " [] subset: ro-eco property_value: IAO:0000112 "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)" xsd:string property_value: IAO:0000112 "osteoclast SubClassOf 'capable of' some 'bone resorption'" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "has function realized in" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20123131 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/21208450 property_value: IAO:0000232 "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"." xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000015 ! process is_a: RO:0002216 ! capable of part of expand_expression_to: "RO_0000053 some (RO_0000054 only ?Y)" [] [Typedef] id: RO:0002216 name: capable of part of def: "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "has function in" xsd:string property_value: seeAlso "defining-property-chains-involving-reflexivity" holds_over_chain: RO:0002215 part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} is_a: RO:0002328 ! functionally related to is_a: RO:0002500 ! causal agent in process expand_expression_to: "RO_0000053 some (RO_0000054 only (BFO_0000050 some ?Y))" [] [Typedef] id: RO:0002222 name: temporally related to comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations. subset: ro-eco property_value: http://purl.org/dc/terms/source https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1 xsd:anyURI property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 https://en.wikipedia.org/wiki/Allen%27s_interval_algebra property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent [Typedef] id: RO:0002233 name: has input def: "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." [] subset: ro-eco property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "consumes" xsd:string domain: BFO:0000015 ! process range: BFO:0000040 ! material entity is_a: RO:0000057 ! has participant inverse_of: RO:0002352 ! input of [Typedef] id: RO:0002258 name: developmentally preceded by def: "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" [] comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "false" xsd:boolean property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "In general you should not use this relation to make assertions - use one of the more specific relations below this one" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: RO:0002324 ! developmentally related to inverse_of: RO:0002286 ! developmentally succeeded by [Typedef] id: RO:0002263 name: acts upstream of def: "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." [] property_value: IAO:0000112 "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision." xsd:string property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of holds_over_chain: RO:0002327 RO:0002411 is_a: RO:0002264 ! acts upstream of or within [Typedef] id: RO:0002264 name: acts upstream of or within def: "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." [] synonym: "affects" RELATED [] property_value: IAO:0000112 "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway." xsd:string property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within holds_over_chain: RO:0002327 RO:0002418 is_a: RO:0002500 ! causal agent in process [Typedef] id: RO:0002286 name: developmentally succeeded by def: "Inverse of developmentally preceded by" [] property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002384 ! has developmental potential involving [Typedef] id: RO:0002304 name: causally upstream of, positive effect comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y property_value: http://purl.org/dc/terms/creator "cjm" xsd:string property_value: RO:0004049 RO:0002411 is_a: RO:0002411 ! causally upstream of is_a: RO:0004047 ! causally upstream of or within, positive effect [Typedef] id: RO:0002305 name: causally upstream of, negative effect comment: holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y property_value: http://purl.org/dc/terms/creator "cjm" xsd:string property_value: RO:0004050 RO:0002411 is_a: RO:0002411 ! causally upstream of is_a: RO:0004046 ! causally upstream of or within, negative effect [Typedef] id: RO:0002323 name: mereotopologically related to def: "A mereological relationship or a topological relationship" [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships" xsd:string property_value: RO:0001900 RO:0001901 [Typedef] id: RO:0002324 name: developmentally related to def: "A relationship that holds between entities participating in some developmental process (GO:0032502)" [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development" xsd:string [Typedef] id: RO:0002327 name: enables property_value: IAO:0000112 "a particular instances of akt-2 enables some instance of protein kinase activity" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "catalyzes" xsd:string property_value: IAO:0000118 "executes" xsd:string property_value: IAO:0000118 "has" xsd:string property_value: IAO:0000118 "is catalyzing" xsd:string property_value: IAO:0000118 "is executing" xsd:string property_value: IAO:0000232 "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized." xsd:string property_value: IAO:0000232 "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time." xsd:string is_a: RO:0002215 ! capable of inverse_of: RO:0002333 ! enabled by transitive_over: has_part ! has part transitive_over: RO:0002017 ! has component activity [Typedef] id: RO:0002328 name: functionally related to def: "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "This is a grouping relation that collects relations used for the purpose of connecting structure and function" xsd:string [Typedef] id: RO:0002329 name: part of structure that is capable of def: "this relation holds between c and p when c is part of some c', and c' is capable of p." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "false" xsd:boolean holds_over_chain: part_of RO:0002215 {http://purl.obolibrary.org/obo/RO_0002581="true"} is_a: RO:0002328 ! functionally related to [Typedef] id: RO:0002331 name: involved in def: "c involved_in p if and only if c enables some process p', and p' is part of p" [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "actively involved in" xsd:string property_value: IAO:0000118 "enables part of" xsd:string property_value: seeAlso Involved:in holds_over_chain: RO:0002327 part_of is_a: RO:0000056 ! participates in is_a: RO:0002431 ! involved in or involved in regulation of transitive_over: part_of ! part of [Typedef] id: RO:0002333 name: enabled by def: "inverse of enables" [] property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0000057 ! has participant is_a: RO:0002328 ! functionally related to [Typedef] id: RO:0002334 name: regulated by def: "inverse of regulates" [] subset: RO:0002259 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000589 "regulated by (processual)" xsd:string domain: BFO:0000015 ! process range: BFO:0000015 ! process is_transitive: true is_a: RO:0002427 ! causally downstream of or within [Typedef] id: RO:0002335 name: negatively regulated by def: "inverse of negatively regulates" [] subset: RO:0002259 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002334 ! regulated by [Typedef] id: RO:0002336 name: positively regulated by def: "inverse of positively regulates" [] subset: RO:0002259 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002334 ! regulated by [Typedef] id: RO:0002352 name: input of def: "inverse of has input" [] subset: ro-eco subset: RO:0002259 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0000056 ! participates in is_a: RO:0002328 ! functionally related to [Typedef] id: RO:0002384 name: has developmental potential involving def: "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)." [] property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string domain: CARO:0000000 ! anatomical entity range: CARO:0000000 ! anatomical entity is_a: RO:0002324 ! developmentally related to [Typedef] id: RO:0002388 name: has potential to directly develop into def: "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y" [] property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: has_potential_to_develop_into ! has potential to develop into [Typedef] id: RO:0002404 name: causally downstream of def: "inverse of upstream of" [] property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: preceded_by ! preceded_by is_a: RO:0002427 ! causally downstream of or within inverse_of: RO:0002411 ! causally upstream of [Typedef] id: RO:0002405 name: immediately causally downstream of property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: immediately_preceded_by ! immediately preceded by is_a: RO:0002404 ! causally downstream of inverse_of: RO:0002412 ! immediately causally upstream of [Typedef] id: RO:0002410 name: causally related to def: "This relation groups causal relations between material entities and causal relations between processes" [] property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000116 "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types." xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string [Typedef] id: RO:0002411 name: causally upstream of def: "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain" [] property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string is_transitive: true is_a: precedes ! precedes is_a: RO:0002418 ! causally upstream of or within [Typedef] id: RO:0002412 name: immediately causally upstream of def: "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q." [] property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: RO:0002575 RO:0002411 is_a: RO:0002090 ! immediately precedes is_a: RO:0002411 ! causally upstream of [Typedef] id: RO:0002418 name: causally upstream of or within def: "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q." [] synonym: "affects" RELATED [] property_value: IAO:0000116 "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "influences (processual)" xsd:string is_transitive: true is_a: RO:0002501 ! causal relation between processes inverse_of: RO:0002427 ! causally downstream of or within [Typedef] id: RO:0002427 name: causally downstream of or within def: "inverse of causally upstream of or within" [] subset: RO:0002259 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations is_transitive: true is_a: RO:0002501 ! causal relation between processes [Typedef] id: RO:0002428 name: involved in regulation of def: "c involved in regulation of p if c is involved in some p' and p' regulates some p" [] property_value: IAO:0000117 "Chris Mungall" xsd:string holds_over_chain: RO:0002327 RO:0002211 holds_over_chain: RO:0002331 RO:0002211 is_a: RO:0002263 ! acts upstream of is_a: RO:0002431 ! involved in or involved in regulation of [Typedef] id: RO:0002429 name: involved in positive regulation of def: "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: RO:0004049 RO:0002428 holds_over_chain: RO:0002327 RO:0002213 holds_over_chain: RO:0002331 RO:0002213 is_a: RO:0002428 ! involved in regulation of [Typedef] id: RO:0002430 name: involved in negative regulation of def: "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: RO:0004050 RO:0002428 holds_over_chain: RO:0002327 RO:0002212 holds_over_chain: RO:0002331 RO:0002212 is_a: RO:0002428 ! involved in regulation of [Typedef] id: RO:0002431 name: involved in or involved in regulation of def: "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" [] property_value: IAO:0000116 "OWL does not allow defining object properties via a Union" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "involved in or reguates" xsd:string is_a: RO:0002264 ! acts upstream of or within is_a: RO:0002328 ! functionally related to is_a: RO:0002500 ! causal agent in process [Typedef] id: RO:0002432 name: is active in def: "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure." [GOC:cjm, GOC:dos] synonym: "enables activity in" EXACT [] property_value: IAO:0000112 "A protein that enables activity in a cytosol." xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "executes activity in" xsd:string holds_over_chain: RO:0002327 BFO:0000066 {http://purl.obolibrary.org/obo/RO_0002581="true"} is_a: RO:0002131 ! overlaps is_a: RO:0002328 ! functionally related to [Typedef] id: RO:0002434 name: interacts with def: "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." [] subset: ro-eco synonym: "in pairwise interaction with" EXACT [] property_value: http://xmlns.com/foaf/0.1/page https://github.com/oborel/obo-relations/wiki/InteractionRelations xsd:anyURI property_value: IAO:0000116 "Considering relabeling as 'pairwise interacts with'" xsd:anyURI property_value: IAO:0000116 "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact." xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules." xsd:string property_value: seeAlso http://purl.obolibrary.org/obo/MI_0914 xsd:anyURI domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_symmetric: true [Typedef] id: RO:0002436 name: molecularly interacts with def: "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "binds" xsd:string property_value: IAO:0000118 "molecularly binds with" xsd:string property_value: seeAlso ECO:0000353 property_value: seeAlso http://purl.obolibrary.org/obo/MI_0915 xsd:anyURI is_symmetric: true is_a: RO:0002434 ! interacts with [Typedef] id: RO:0002447 name: phosphorylates property_value: IAO:0000116 "Axiomatization to GO to be added later" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000118 "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y." xsd:string is_a: RO:0002436 ! molecularly interacts with [Typedef] id: RO:0002448 name: directly regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B." [] synonym: "molecularly controls" EXACT [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "Vasundra Touré" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: RO:0002436 ! molecularly interacts with is_a: RO:0011002 ! regulates activity of [Typedef] id: RO:0002449 name: directly negatively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B." [] synonym: "molecularly decreases activity of" EXACT [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "Vasundra Touré" xsd:string property_value: IAO:0000118 "directly inhibits" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: RO:0002448 ! directly regulates activity of [Typedef] id: RO:0002450 name: directly positively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B." [] synonym: "molecularly increases activity of" EXACT [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "Vasundra Touré" xsd:string property_value: IAO:0000118 "directly activates" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: RO:0002448 ! directly regulates activity of [Typedef] id: RO:0002464 name: helper property (not for use in curation) property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning." xsd:string [Typedef] id: RO:0002479 name: has part that occurs in def: "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." [] subset: ro-eco property_value: IAO:0000117 "Chris Mungall" xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000004 ! independent continuant holds_over_chain: has_part BFO:0000066 {http://purl.obolibrary.org/obo/RO_0002581="true"} [Typedef] id: RO:0002481 name: is kinase activity property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002564 ! molecular interaction relation helper property [Typedef] id: RO:0002487 name: relation between physical entity and a process or stage property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage." xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000003 ! occurrent [Typedef] id: RO:0002490 name: existence overlaps def: "x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))" [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002487 ! relation between physical entity and a process or stage [Typedef] id: RO:0002500 name: causal agent in process def: "A relationship between a material entity and a process where the material entity has some causal role that influences the process" [] property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations is_a: RO:0002595 ! causal relation between material entity and a process inverse_of: RO:0002608 ! process has causal agent [Typedef] id: RO:0002501 name: causal relation between processes def: "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent is_a: RO:0002410 ! causally related to [Typedef] id: RO:0002506 name: causal relation between entities property_value: IAO:0000116 "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: RO:0002410 ! causally related to [Typedef] id: RO:0002559 name: causally influenced by property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influenced by (entity-centric)" xsd:string is_a: RO:0002506 ! causal relation between entities inverse_of: RO:0002566 ! causally influences [Typedef] id: RO:0002563 name: interaction relation helper property property_value: http://xmlns.com/foaf/0.1/page https://github.com/oborel/obo-relations/wiki/InteractionRelations xsd:anyURI property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29 is_a: RO:0002464 ! helper property (not for use in curation) [Typedef] id: RO:0002564 name: molecular interaction relation helper property property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002563 ! interaction relation helper property [Typedef] id: RO:0002566 name: causally influences def: "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "Vasundra Touré" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influences (entity-centric)" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: RO:0002506 ! causal relation between entities [Typedef] id: RO:0002578 name: directly regulates def: "Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." [] property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly regulates (processual)" xsd:string property_value: RO:0002575 RO:0002211 is_a: RO:0002211 ! regulates is_a: RO:0002412 ! immediately causally upstream of [Typedef] id: RO:0002584 name: has part structure that is capable of def: "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" [] property_value: IAO:0000112 "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string holds_over_chain: has_part RO:0002215 is_a: RO:0002328 ! functionally related to is_a: RO:0002595 ! causal relation between material entity and a process [Typedef] id: RO:0002595 name: causal relation between material entity and a process def: "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." [] property_value: IAO:0000116 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations domain: BFO:0000040 ! material entity range: BFO:0000015 ! process is_a: RO:0002410 ! causally related to [Typedef] id: RO:0002596 name: capable of regulating def: "Holds between c and p if and only if c is capable of some activity a, and a regulates p." [] property_value: IAO:0000112 "pyrethroid -> growth" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations holds_over_chain: RO:0002215 RO:0002211 is_a: RO:0002500 ! causal agent in process [Typedef] id: RO:0002597 name: capable of negatively regulating def: "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." [] property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations holds_over_chain: RO:0002215 RO:0002212 is_a: RO:0002596 ! capable of regulating [Typedef] id: RO:0002598 name: capable of positively regulating def: "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." [] property_value: IAO:0000112 "renin -> arteriolar smooth muscle contraction" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations holds_over_chain: RO:0002215 RO:0002213 is_a: RO:0002596 ! capable of regulating [Typedef] id: RO:0002608 name: process has causal agent def: "Inverse of 'causal agent in process'" [] property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations is_a: RO:0002410 ! causally related to [Typedef] id: RO:0002629 name: directly positively regulates def: "Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2." [] property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly positively regulates (process to process)" xsd:string property_value: RO:0004049 RO:0002578 is_a: RO:0002213 ! positively regulates is_a: RO:0002578 ! directly regulates [Typedef] id: RO:0002630 name: directly negatively regulates def: "Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2." [] property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly negatively regulates (process to process)" xsd:string property_value: RO:0004050 RO:0002578 is_a: RO:0002212 ! negatively regulates is_a: RO:0002578 ! directly regulates [Typedef] id: RO:0004031 name: enables subfunction def: "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." [] holds_over_chain: RO:0002327 has_part is_a: RO:0002328 ! functionally related to created_by: cjm creation_date: 2018-01-25T23:20:13Z [Typedef] id: RO:0004032 name: acts upstream of or within, positive effect property_value: RO:0004049 RO:0002264 property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect holds_over_chain: RO:0002327 RO:0004047 is_a: RO:0002264 ! acts upstream of or within created_by: cjm creation_date: 2018-01-26T23:49:30Z [Typedef] id: RO:0004033 name: acts upstream of or within, negative effect property_value: RO:0004050 RO:0002264 holds_over_chain: RO:0002327 RO:0004046 is_a: RO:0002264 ! acts upstream of or within created_by: cjm creation_date: 2018-01-26T23:49:51Z [Typedef] id: RO:0004034 name: acts upstream of, positive effect def: "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" [] property_value: RO:0004049 RO:0002263 property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect holds_over_chain: RO:0002327 RO:0002304 is_a: RO:0002263 ! acts upstream of is_a: RO:0004032 ! acts upstream of or within, positive effect created_by: cjm creation_date: 2018-01-26T23:53:14Z [Typedef] id: RO:0004035 name: acts upstream of, negative effect def: "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" [] property_value: RO:0004050 RO:0002263 property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect holds_over_chain: RO:0002327 RO:0002305 is_a: RO:0002263 ! acts upstream of is_a: RO:0004033 ! acts upstream of or within, negative effect created_by: cjm creation_date: 2018-01-26T23:53:22Z [Typedef] id: RO:0004046 name: causally upstream of or within, negative effect property_value: RO:0004050 RO:0002418 is_a: RO:0002418 ! causally upstream of or within created_by: cjm creation_date: 2018-03-13T23:55:05Z [Typedef] id: RO:0004047 name: causally upstream of or within, positive effect property_value: RO:0004049 RO:0002418 is_a: RO:0002418 ! causally upstream of or within created_by: cjm creation_date: 2018-03-13T23:55:19Z [Typedef] id: RO:0011002 name: regulates activity of def: "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." [] property_value: IAO:0000117 "Vasundra Touré" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: RO:0002566 ! causally influences [Typedef] id: developmentally_contributes_to name: developmentally contributes to name: developmentally_contributes_to namespace: uberon def: "inverse of has developmental contribution from" [] subset: RO:0002259 xref: RO:0002255 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by [Typedef] id: develops_from name: develops from name: develops_from namespace: uberon def: "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" [] comment: This is the transitive form of the develops from relation xref: RO:0002202 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000117 "Melissa Haendel" xsd:string property_value: IAO:0000117 "Terry Meehan" xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000004 ! independent continuant holds_over_chain: part_of develops_from is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by inverse_of: develops_into ! develops_into transitive_over: part_of ! part of [Typedef] id: develops_into name: develops into name: develops_into namespace: uberon def: "inverse of develops from" [] subset: RO:0002259 xref: RO:0002203 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000117 "Terry Meehan" xsd:string is_transitive: true is_a: has_potential_to_develop_into ! has potential to develop into is_a: RO:0002286 ! developmentally succeeded by is_a: RO:0002388 ! has potential to directly develop into [Typedef] id: ends name: ends namespace: uberon def: "Relation between occurrents, shares an end boundary with." [Allen:starts, https://orcid.org/0000-0002-6601-2165, ZFS:finishes] synonym: "finishes" EXACT [] xref: RO:0002229 is_a: part_of ! part of [Typedef] id: ends_with name: ends with namespace: uberon xref: RO:0002230 is_transitive: true is_a: has_part ! has part [Typedef] id: existence_ends_during name: existence ends during namespace: uberon def: "Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely." [https://orcid.org/0000-0002-6601-2165] def: "x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. synonym: "ceases_to_exist_during" EXACT [] xref: RO:0002492 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: existence_ends_during_or_before ! existence ends during or before is_a: RO:0002490 ! existence overlaps transitive_over: part_of ! part of [Typedef] id: existence_ends_during_or_before name: existence ends during or before namespace: uberon def: "x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002497 property_value: IAO:0000117 "Chris Mungall" xsd:string holds_over_chain: part_of existence_ends_during_or_before holds_over_chain: RO:0002286 existence_ends_during_or_before is_a: RO:0002487 ! relation between physical entity and a process or stage transitive_over: part_of ! part of transitive_over: precedes ! precedes [Typedef] id: existence_starts_during name: existence starts during namespace: uberon def: "Relation between continuant c and occurrent s, such that every instance of c comes into existing during some s." [https://orcid.org/0000-0002-6601-2165] def: "x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y)." [] synonym: "begins_to_exist_during" EXACT [] xref: RO:0002488 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: existence_starts_during_or_after ! existence starts during or after is_a: RO:0002490 ! existence overlaps transitive_over: part_of ! part of [Typedef] id: existence_starts_during_or_after name: existence starts during or after namespace: uberon def: "x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002496 property_value: IAO:0000117 "Chris Mungall" xsd:string holds_over_chain: part_of existence_starts_during_or_after holds_over_chain: RO:0002258 existence_starts_during_or_after is_a: RO:0002487 ! relation between physical entity and a process or stage transitive_over: part_of ! part of transitive_over: preceded_by ! preceded_by [Typedef] id: has_developmental_contribution_from name: has developmental contribution from namespace: uberon def: "x has developmental contribution from y iff x has some part z such that z develops from y" [] xref: RO:0002254 property_value: IAO:0000112 "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string domain: CARO:0000000 ! anatomical entity range: CARO:0000000 ! anatomical entity holds_over_chain: has_part develops_from is_transitive: true is_a: RO:0002258 ! developmentally preceded by inverse_of: developmentally_contributes_to ! developmentally contributes to [Typedef] id: has_part name: has part namespace: uberon def: "a core relation that holds between a whole and its part" [] xref: BFO:0000051 property_value: IAO:0000111 "has part" xsd:string property_value: IAO:0000112 "my body has part my brain (continuant parthood, two material entities)" xsd:string property_value: IAO:0000112 "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)" xsd:string property_value: IAO:0000112 "this year has part this day (occurrent parthood)" xsd:string property_value: IAO:0000116 "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part." xsd:string property_value: IAO:0000116 "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime" xsd:string property_value: IAO:0000116 "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'." xsd:string property_value: IAO:0000118 "has_part" xsd:string property_value: RO:0001900 RO:0001901 is_transitive: true is_a: RO:0002131 ! overlaps [Typedef] id: has_potential_to_develop_into name: has potential to develop into namespace: uberon def: "x has the potential to develop into y iff x develops into y or if x is capable of developing into y" [] xref: RO:0002387 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002384 ! has developmental potential involving [Typedef] id: has_potential_to_developmentally_contribute_to name: has potential to developmentally contribute to namespace: uberon def: "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y" [] xref: RO:0002385 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string is_a: RO:0002384 ! has developmental potential involving [Typedef] id: immediately_preceded_by name: immediately preceded by name: immediately_preceded_by namespace: uberon def: "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" [] comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) synonym: "directly preceded by" EXACT [] synonym: "is directly preceded by" EXACT [] synonym: "is immediately preceded by" EXACT [SIO:000251] synonym: "starts_at_end_of" EXACT [] xref: RO:0002087 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000118 "starts_at_end_of" xsd:string property_value: seeAlso SIO:000251 property_value: UBPROP:0000001 "A non-transitive temporal relation in which one process immediately precedes another process, such that there is no interval of time between the two processes[SIO:000251]." xsd:string {source="SIO:000251"} is_a: preceded_by ! preceded_by inverse_of: RO:0002090 ! immediately precedes [Typedef] id: part_of name: part of namespace: uberon def: "a core relation that holds between a part and its whole" [] xref: BFO:0000050 property_value: IAO:0000111 "is part of" xsd:string property_value: IAO:0000112 "my brain is part of my body (continuant parthood, two material entities)" xsd:string property_value: IAO:0000112 "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)" xsd:string property_value: IAO:0000112 "this day is part of this year (occurrent parthood)" xsd:string property_value: IAO:0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other." xsd:string property_value: IAO:0000116 "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime" xsd:string property_value: IAO:0000116 "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'." xsd:string property_value: IAO:0000118 "part_of" xsd:string property_value: RO:0001900 RO:0001901 property_value: RO:0040042 BFO:0000002 property_value: RO:0040042 BFO:0000003 property_value: RO:0040042 BFO:0000004 property_value: RO:0040042 BFO:0000017 property_value: RO:0040042 BFO:0000019 property_value: RO:0040042 BFO:0000020 property_value: RO:0040042 BFO:0000031 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:PartOf property_value: seeAlso http://www.obofoundry.org/ro/#OBO_REL:part_of xsd:string is_transitive: true is_a: RO:0002131 ! overlaps inverse_of: has_part ! has part [Typedef] id: preceded_by name: preceded by name: preceded_by namespace: uberon def: "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] def: "X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X)" [] subset: ro-eco synonym: "is preceded by" EXACT [SIO:000249] synonym: "takes place after" EXACT [Allen:precedes] xref: BFO:0000062 property_value: http://purl.org/dc/elements/1.1/source http://www.obofoundry.org/ro/#OBO_REL:preceded_by xsd:string property_value: IAO:0000111 "preceded by" xsd:string property_value: IAO:0000116 "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other." xsd:string property_value: IAO:0000118 "is preceded by" xsd:string property_value: IAO:0000118 "preceded_by" xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent holds_over_chain: part_of preceded_by is_transitive: true is_a: RO:0002086 ! ends after inverse_of: precedes ! precedes [Typedef] id: precedes name: precedes namespace: uberon def: "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: BFO:0000063 property_value: IAO:0000111 "precedes" xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent holds_over_chain: part_of precedes is_transitive: true is_a: RO:0002222 ! temporally related to [Typedef] id: starts name: starts namespace: uberon def: "Relation between occurrents, shares a start boundary with." [Allen:starts, https://orcid.org/0000-0002-6601-2165] xref: RO:0002223 is_a: part_of ! part of inverse_of: starts_with ! starts with [Typedef] id: starts_with name: starts with namespace: uberon xref: RO:0002224 is_transitive: true is_a: has_part ! has part