Echinoderm Anatomy and Development Ontology
type: Ontology
version IRI: ecao.owl
description: None
license: https://creativecommons.org/licenses/by/3.0/

definition
type: AnnotationProperty
IAO_0000111: definition
IAO_0000114: IAO_0000122
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
editor note: 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.
IAO_0000117: PERSON:Daniel Schober
IAO_0000119: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

editor note
type: AnnotationProperty
definition: An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
database_cross_reference: IAO:0000116
has OBO namespace: uberon
id: editor_note
is metadata tag: true
shorthand: editor_note

is a defining property chain axiom
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL

is a defining property chain axiom where second argument is reflexive
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.

database_cross_reference
type: AnnotationProperty
IAO_0000112: disease characteristic (MONDO:0021125) has cross-reference (http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NCIT:C41009"^^xsd:string
definition: An annotation property that links an ontology entity or a statement to a prefixed identifier or URI.
IAO_0000233: https://github.com/information-artifact-ontology/ontology-metadata/issues/123
contributor: https://orcid.org/0000-0002-7356-1779
created: 2024-03-18
label: has cross-reference

has_exact_synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has the exact same meaning than the preferred name/primary label.
IAO_0000117: http://orcid.org/0000-0001-5208-3432
IAO_0000233: https://github.com/information-artifact-ontology/ontology-metadata/issues/20
label: has exact synonym

see also
type: AnnotationProperty
has OBO namespace: spatial
has OBO namespace: uberon
id: seeAlso
is metadata tag: true
shorthand: seeAlso

part of
type: ObjectProperty
sub property of: overlaps
inverse of: has part
type: TransitiveProperty
IAO_0000111: is part of
IAO_0000112: my brain is part of my body (continuant parthood, two material entities)
IAO_0000112: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
IAO_0000112: this day is part of this year (occurrent parthood)
definition: a core relation that holds between a part and its whole
editor note: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
IAO_0000118: part_of
RO_0001900: RO_0001901
RO_0040042: continuant
RO_0040042: occurrent
RO_0040042: independent continuant
RO_0040042: realizable entity
RO_0040042: quality
RO_0040042: specifically dependent continuant
RO_0040042: BFO_0000031
database_cross_reference: BFO:0000050
has OBO namespace: spatial
has OBO namespace: uberon
id: part_of
in subset: valid for go annotation extension
in subset: valid for go gp2term
in subset: valid for go ontology
in subset: valid for gocam
shorthand: part_of

has part
type: ObjectProperty
sub property of: overlaps
type: TransitiveProperty
IAO_0000111: has part
IAO_0000112: my body has part my brain (continuant parthood, two material entities)
IAO_0000112: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
IAO_0000112: this year has part this day (occurrent parthood)
definition: a core relation that holds between a whole and its part
editor note: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
IAO_0000118: has_part
RO_0001900: RO_0001901
database_cross_reference: BFO:0000051
has OBO namespace: spatial
has OBO namespace: uberon
id: has_part
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
shorthand: has_part

preceded by
type: ObjectProperty
sub property of: ends after
inverse of: precedes
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
IAO_0000111: preceded by
definition: x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
editor note: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
IAO_0000118: is preceded by
IAO_0000118: preceded_by
source: http://www.obofoundry.org/ro/#OBO_REL:preceded_by
database_cross_reference: BFO:0000062
has OBO namespace: uberon
id: preceded_by
in subset: ro-eco
shorthand: preceded_by

precedes
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
IAO_0000111: precedes
definition: x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
database_cross_reference: BFO:0000063
has OBO namespace: uberon
id: precedes
in subset: ro-eco
shorthand: precedes

occurs in
type: ObjectProperty
inverse of: contains process
domain: occurrent
range: independent continuant
property chain axiom: part of
definition: b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant

contains process
type: ObjectProperty
definition: [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
database_cross_reference: BFO:0000067
has OBO namespace: uberon
id: contains_process
shorthand: contains_process
comment: Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant

anterior to
type: ObjectProperty
inverse of: posterior to
type: TransitiveProperty
definition: x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:0000096
has_exact_synonym: rostral_to
has OBO namespace: spatial
has OBO namespace: uberon
id: anterior_to
shorthand: anterior_to

Axiom
annotated source: anterior to
annotated property: definition
annotated target: x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:cjm

distal to
type: ObjectProperty
inverse of: proximal to
type: TransitiveProperty
definition: x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal).
database_cross_reference: BSPO:0000097
has OBO namespace: spatial
has OBO namespace: uberon
id: distal_to
shorthand: distal_to

Axiom
annotated source: distal to
annotated property: definition
annotated target: x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal).
database_cross_reference: BSPO:cjm

dorsal to
type: ObjectProperty
inverse of: ventral to
type: TransitiveProperty
definition: x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:0000098
has OBO namespace: spatial
has OBO namespace: uberon
id: dorsal_to
shorthand: dorsal_to

Axiom
annotated source: dorsal to
annotated property: definition
annotated target: x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:cjm

posterior to
type: ObjectProperty
type: TransitiveProperty
definition: x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:0000099
has narrow synonym: caudal to
has OBO namespace: spatial
has OBO namespace: uberon
id: posterior_to
shorthand: posterior_to

Axiom
annotated source: posterior to
annotated property: definition
annotated target: x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:cjm

Axiom
annotated source: posterior to
annotated property: hasNarrowSynonym
annotated target: caudal to
has synonym type: vertebrate

proximal to
type: ObjectProperty
type: TransitiveProperty
definition: x proximal to y iff x is closer to the point of attachment with the body than y.
database_cross_reference: BSPO:0000100
database_cross_reference: NCIT:C25236
has OBO namespace: spatial
has OBO namespace: uberon
id: proximal_to
shorthand: proximal_to
comment: The elbow is proximal to the hand, but distal to the shoulder.

Axiom
annotated source: proximal to
annotated property: definition
annotated target: x proximal to y iff x is closer to the point of attachment with the body than y.
database_cross_reference: BSPO:cjm

ventral to
type: ObjectProperty
type: TransitiveProperty
definition: x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:0000102
has OBO namespace: spatial
has OBO namespace: uberon
id: ventral_to
shorthand: ventral_to

Axiom
annotated source: ventral to
annotated property: definition
annotated target: x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:cjm

deep to
type: ObjectProperty
inverse of: superficial to
type: TransitiveProperty
definition: Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines.
database_cross_reference: BSPO:0000107
has OBO namespace: spatial
has OBO namespace: uberon
id: deep_to
shorthand: deep_to

Axiom
annotated source: deep to
annotated property: definition
annotated target: Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines.
database_cross_reference: BSPO:cjm

superficial to
type: ObjectProperty
type: TransitiveProperty
definition: Near the outer surface of the organism. Thus, skin is superficial to the muscle layer.
database_cross_reference: BSPO:0000108
has OBO namespace: spatial
has OBO namespace: uberon
id: superficial_to
shorthand: superficial_to

Axiom
annotated source: superficial to
annotated property: definition
annotated target: Near the outer surface of the organism. Thus, skin is superficial to the muscle layer.
database_cross_reference: BSPO:cjm

in left side of
type: ObjectProperty
sub property of: in lateral side of
property disjoint with: in right side of
definition: X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion.
database_cross_reference: BSPO:0000120
database_cross_reference: NCIT:C25229
has OBO namespace: spatial
has OBO namespace: uberon
id: in_left_side_of
shorthand: in_left_side_of

Axiom
annotated source: in left side of
annotated property: definition
annotated target: X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion.
database_cross_reference: BSPO:PATO_mtg_2009

in right side of
type: ObjectProperty
sub property of: in lateral side of
definition: X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion.
database_cross_reference: BSPO:0000121
database_cross_reference: NCIT:C25228
has OBO namespace: spatial
has OBO namespace: uberon
id: in_right_side_of
shorthand: in_right_side_of

Axiom
annotated source: in right side of
annotated property: definition
annotated target: X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion.
database_cross_reference: BSPO:PATO_mtg_2009

in posterior side of
type: ObjectProperty
sub property of: part of
definition: X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion.
database_cross_reference: BSPO:0000122
has OBO namespace: spatial
has OBO namespace: uberon
id: in_posterior_side_of
shorthand: in_posterior_side_of

Axiom
annotated source: in posterior side of
annotated property: definition
annotated target: X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion.
database_cross_reference: BSPO:PATO_mtg_2009

in anterior side of
type: ObjectProperty
sub property of: part of
definition: X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion.
database_cross_reference: BSPO:0000123
has OBO namespace: spatial
has OBO namespace: uberon
id: in_anterior_side_of
shorthand: in_anterior_side_of

Axiom
annotated source: in anterior side of
annotated property: definition
annotated target: X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion.
database_cross_reference: BSPO:PATO_mtg_2009

in proximal side of
type: ObjectProperty
sub property of: part of
definition: x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion.
database_cross_reference: BSPO:0000124
has OBO namespace: spatial
has OBO namespace: uberon
id: in_proximal_side_of
shorthand: in_proximal_side_of

Axiom
annotated source: in proximal side of
annotated property: definition
annotated target: x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion.
database_cross_reference: BSPO:PATO_mtg_2009

in distal side of
type: ObjectProperty
sub property of: part of
definition: x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion.
database_cross_reference: BSPO:0000125
has OBO namespace: spatial
has OBO namespace: uberon
id: in_distal_side_of
shorthand: in_distal_side_of

Axiom
annotated source: in distal side of
annotated property: definition
annotated target: x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion.
database_cross_reference: BSPO:PATO_mtg_2009

in lateral side of
type: ObjectProperty
sub property of: part of
definition: X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure
database_cross_reference: BSPO:0000126
has OBO namespace: spatial
has OBO namespace: uberon
id: in_lateral_side_of
shorthand: in_lateral_side_of

Axiom
annotated source: in lateral side of
annotated property: definition
annotated target: X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure
database_cross_reference: UBERON:cjm

proximalmost part of
type: ObjectProperty
sub property of: in proximal side of
definition: X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y
database_cross_reference: BSPO:0001106
has OBO namespace: spatial
has OBO namespace: uberon
id: proximalmost_part_of
shorthand: proximalmost_part_of

Axiom
annotated source: proximalmost part of
annotated property: definition
annotated target: X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y
database_cross_reference: https://orcid.org/0000-0002-6601-2165

immediately deep to
type: ObjectProperty
sub property of: deep to
inverse of: immediately superficial to
definition: x immediately deep to y iff x deep_to y and x is contiguous with y.
database_cross_reference: BSPO:0001107
has OBO namespace: spatial
has OBO namespace: uberon
id: immediately_deep_to
shorthand: immediately_deep_to

Axiom
annotated source: immediately deep to
annotated property: definition
annotated target: x immediately deep to y iff x deep_to y and x is contiguous with y.
database_cross_reference: BSPO:curators

distalmost part of
type: ObjectProperty
sub property of: in distal side of
definition: X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y
database_cross_reference: BSPO:0001108
has OBO namespace: spatial
has OBO namespace: uberon
id: distalmost_part_of
shorthand: distalmost_part_of

Axiom
annotated source: distalmost part of
annotated property: definition
annotated target: X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y
database_cross_reference: https://orcid.org/0000-0002-6601-2165

intersects midsagittal plane of
type: ObjectProperty
sub property of: part of
definition: X intersects median plane of iff X crosses the midine plane of Y.
database_cross_reference: BSPO:0005001
has OBO namespace: spatial
has OBO namespace: uberon
id: intersects_midsagittal_plane_of
shorthand: intersects_midsagittal_plane_of

immediately superficial to
type: ObjectProperty
sub property of: superficial to
sub property of: adjacent to
definition: x immediately superficial to y iff x superficial to y and x is contiguous with y.
database_cross_reference: BSPO:0015014
has OBO namespace: spatial
has OBO namespace: uberon
id: immediately_superficial_to
shorthand: immediately_superficial_to

Axiom
annotated source: immediately superficial to
annotated property: definition
annotated target: x immediately superficial to y iff x superficial to y and x is contiguous with y.
database_cross_reference: BSPO:curators

in dorsal side of
type: ObjectProperty
sub property of: part of
definition: X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion.
database_cross_reference: BSPO:0015101
has OBO namespace: spatial
has OBO namespace: uberon
id: in_dorsal_side_of
shorthand: in_dorsal_side_of

Axiom
annotated source: in dorsal side of
annotated property: definition
annotated target: X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion.
database_cross_reference: BSPO:cjm

lacks_part
type: ObjectProperty

lacks_plasma_membrane_part
type: ObjectProperty

results in distribution of
type: ObjectProperty
database_cross_reference: GOREL:0002003
has OBO namespace: external
id: results_in_distribution_of
shorthand: results_in_distribution_of
label: results_in_distribution_of

results in fission of
type: ObjectProperty
sub property of: has participant
database_cross_reference: GOREL:0002004
has OBO namespace: external
id: results_in_fission_of
shorthand: results_in_fission_of
label: results_in_fission_of

characteristic of
type: ObjectProperty
sub property of: characteristic of part of
inverse of: has characteristic
type: FunctionalProperty
IAO_0000111: inheres in
IAO_0000112: this fragility is a characteristic of this vase
IAO_0000112: this red color is a characteristic of this apple
definition: a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
IAO_0000118: inheres_in
RO_0001900: RO_0001901
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.

has characteristic
type: ObjectProperty
type: InverseFunctionalProperty
range: specifically dependent continuant
IAO_0000111: bearer of
IAO_0000112: this apple is bearer of this red color
IAO_0000112: this vase is bearer of this fragility
definition: Inverse of characteristic_of
editor note: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
IAO_0000118: bearer_of
IAO_0000118: is bearer of
RO_0001900: RO_0001901

participates in
type: ObjectProperty
inverse of: has participant
domain: continuant
range: occurrent
IAO_0000111: participates in
IAO_0000112: this blood clot participates in this blood coagulation
IAO_0000112: this input material (or this output material) participates in this process
IAO_0000112: this investigator participates in this investigation
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
IAO_0000118: participates_in
database_cross_reference: RO:0000056
has OBO namespace: uberon
id: participates_in
shorthand: participates_in

has participant
type: ObjectProperty
domain: occurrent
range: continuant
property chain axiom: has part
IAO_0000111: has participant
IAO_0000112: this blood coagulation has participant this blood clot
IAO_0000112: this investigation has participant this investigator
IAO_0000112: this process has participant this input material (or this output material)
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
editor note: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
IAO_0000118: has_participant
source: http://www.obofoundry.org/ro/#OBO_REL:has_participant

function of
type: ObjectProperty
sub property of: characteristic of
inverse of: has function
domain: function
IAO_0000112: this catalysis function is a function of this enzyme
definition: a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
editor note: A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists.
IAO_0000118: function_of
IAO_0000118: is function of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

quality of
type: ObjectProperty
sub property of: characteristic of
inverse of: has quality
IAO_0000112: this red color is a quality of this apple
definition: a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
editor note: A quality inheres in its bearer at all times for which the quality exists.
IAO_0000118: is quality of
IAO_0000118: quality_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

role of
type: ObjectProperty
sub property of: characteristic of
inverse of: has role
IAO_0000112: this investigator role is a role of this person
definition: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
editor note: A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
IAO_0000118: is role of
IAO_0000118: role_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has function
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: function
IAO_0000112: this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)
definition: a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
editor note: A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists.
IAO_0000118: has_function

has quality
type: ObjectProperty
sub property of: has characteristic
range: quality
IAO_0000112: this apple has quality this red color
definition: a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
editor note: A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.
IAO_0000118: has_quality
database_cross_reference: RO:0000086
has OBO namespace: uberon
id: has_quality
shorthand: has_quality

has role
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: role
IAO_0000112: this person has role this investigator role (more colloquially: this person has this role of investigator)
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
editor note: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
IAO_0000118: has_role

has disposition
type: ObjectProperty
sub property of: has characteristic
inverse of: disposition of
domain: independent continuant
range: disposition
definition: a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence

disposition of
type: ObjectProperty
sub property of: characteristic of
definition: inverse of has disposition
in subset: RO_0002259
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

location of
type: ObjectProperty
inverse of: located in
type: TransitiveProperty
IAO_0000112: my head is the location of my brain
IAO_0000112: this cage is the location of this rat
definition: a relation between two independent continuants, the location and the target, in which the target is entirely within the location
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
database_cross_reference: RO:0001015
has OBO namespace: uberon
id: location_of
shorthand: location_of

located in
type: ObjectProperty
type: TransitiveProperty
domain: independent continuant
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
range: independent continuant
range: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
property chain axiom: part of
IAO_0000112: my brain is located in my head
IAO_0000112: this rat is located in this cage
definition: a relation between two independent continuants, the target and the location, in which the target is entirely within the location
editor note: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
database_cross_reference: RO:0001025
has OBO namespace: uberon
id: located_in
in subset: valid for go gp2term
shorthand: located_in

Axiom
annotated source: located in
annotated property: domain
annotated target: independent continuant
editor note: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

Axiom
annotated source: located in
annotated property: range
annotated target: independent continuant
editor note: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

2D boundary of
type: ObjectProperty
sub property of: mereotopologically related to
inverse of: has 2D boundary
IAO_0000112: the surface of my skin is a 2D boundary of my body
definition: a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity
editor note: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
editor note: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.

has 2D boundary
type: ObjectProperty
sub property of: mereotopologically related to
domain: material entity
range: immaterial entity
IAO_0000112: my body has 2D boundary the surface of my skin
definition: a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity
editor note: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
editor note: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.
database_cross_reference: RO:0002002
has OBO namespace: uberon
id: has_boundary
shorthand: has_boundary

innervated_by
type: ObjectProperty
inverse of: innervates
domain: UBERON_0000061
range: UBERON_0000122
property chain axiom: branching part of
database_cross_reference: RO:0002005
has OBO namespace: uberon
id: innervated_by
shorthand: innervated_by

bounding layer of
type: ObjectProperty
sub property of: part of
domain: Class
  intersection of: material entity
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002124
range: material entity
definition: X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000
database_cross_reference: RO:0002007
has OBO namespace: uberon
id: bounding_layer_of
in subset: ro-eco
shorthand: bounding_layer_of
comment: A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane.

has regulatory component activity
type: ObjectProperty
sub property of: has component activity
sub property of: regulated by
definition: A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-05-24T09:30:46Z

has negative regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: negatively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-05-24T09:31:01Z
comment: By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.

has positive regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: positively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-05-24T09:31:17Z
comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.

has component activity
type: ObjectProperty
sub property of: has component process
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-05-24T09:44:33Z
comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.

has component process
type: ObjectProperty
sub property of: has component
domain: process
range: process
definition: w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-05-24T09:49:21Z

occurs across
type: ObjectProperty
sub property of: has part that occurs in
definition: A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-07-20T17:19:37Z

directly regulated by
type: ObjectProperty
sub property of: regulated by
inverse of: directly regulates
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-09-17T13:52:24Z
comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.

Axiom
annotated source: directly regulated by
annotated property: comment
annotated target: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

directly negatively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly negatively regulates
definition: Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-09-17T13:52:38Z

Axiom
annotated source: directly negatively regulated by
annotated property: definition
annotated target: Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

directly positively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly positively regulates
definition: Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-09-17T13:52:47Z

Axiom
annotated source: directly positively regulated by
annotated property: definition
annotated target: Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

has effector activity
type: ObjectProperty
sub property of: has component activity
type: FunctionalProperty
definition: A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-09-22T14:14:36Z
comment: This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.

Axiom
annotated source: has effector activity
annotated property: definition
annotated target: A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

before or simultaneous with
type: ObjectProperty
sub property of: temporally related to
in subset: ro-eco
comment: Primitive instance level timing relation between events

simultaneous with
type: ObjectProperty
sub property of: before or simultaneous with
type: SymmetricProperty
type: TransitiveProperty
definition: x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time.
database_cross_reference: RO:0002082
has OBO namespace: uberon
id: simultaneous_with
in subset: ro-eco
shorthand: simultaneous_with
comment: t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2)

ends after
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
IAO_0000117: David Osumi-Sutherland
in subset: ro-eco
comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)

immediately preceded by
type: ObjectProperty
sub property of: preceded by
inverse of: immediately precedes
property chain axiom: starts with
property chain axiom: ends with
IAO_0000117: David Osumi-Sutherland
IAO_0000118: starts_at_end_of
database_cross_reference: RO:0002087
has OBO namespace: uberon
id: immediately_preceded_by
shorthand: immediately_preceded_by
comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)

immediately precedes
type: ObjectProperty
sub property of: precedes
property chain axiom: ends with
property chain axiom: starts with
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: David Osumi-Sutherland
IAO_0000118: ends_at_start_of
IAO_0000118: meets
RO_0002575: precedes
in subset: ro-eco
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)

has soma location
type: ObjectProperty
sub property of: overlaps
domain: neuron
range: UBERON_0000465
property chain axiom: part of
definition: Relation between a neuron and a material anatomical entity that its soma is part of.

synapsed by
type: ObjectProperty
sub property of: receives input from
inverse of: synapsed to
range: Class
  union of: neuron
  union of: Restriction
    on property: part of
    some values from: neuron
definition: Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it.
database_cross_reference: RO:0002103
has OBO namespace: uberon
id: synapsed_by
shorthand: synapsed_by

has plasma membrane part
type: ObjectProperty
sub property of: has part
domain: UBERON_0000465
range: UBERON_0000465
IAO_0000112: Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]
definition: Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.

synapsed to
type: ObjectProperty
sub property of: sends output to
domain: Class
  union of: neuron
  union of: Restriction
    on property: part of
    some values from: neuron
definition: Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
comment: N1 synapsed_to some N2 Expands to: N1 SubclassOf ( has_part some ( ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( ‘synapse ; GO:0045202’ that has_part some ( ‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))

overlaps
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
property chain axiom: part of
property chain axiom: has part
IAO_0000114: IAO_0000125
definition: x overlaps y if and only if there exists some z such that x has part z and z part of y
definition: x overlaps y iff they have some part in common.
IAO_0000424: http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
RO_0001900: RO_0001901
database_cross_reference: RO:0002131
has OBO namespace: spatial
has OBO namespace: uberon
id: overlaps
in subset: valid for go annotation extension
in subset: valid for gocam
in subset: ro-eco
shorthand: overlaps
comment: "(forall (x y) (iff (overlaps x y) (exists (z) (and (part of z x) (part of z y)))))" CLIF []

Axiom
annotated source: overlaps
annotated property: propertyChainAxiom
annotated target: has part
annotated target: part of
RO_0002582: true

Axiom
annotated source: overlaps
annotated property: definition
annotated target: x overlaps y iff they have some part in common.
database_cross_reference: BSPO:cjm

innervates
type: ObjectProperty
domain: UBERON_0000122
property chain axiom: part of
definition: Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.
database_cross_reference: RO:0002134
has OBO namespace: uberon
id: innervates
shorthand: innervates

continuous with
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
domain: independent continuant
range: independent continuant
definition: X continuous_with Y if and only if X and Y share a fiat boundary.
IAO_0000232: The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)
database_cross_reference: RO:0002150
has OBO namespace: uberon
id: continuous_with
shorthand: continuous_with

only in taxon
type: ObjectProperty
sub property of: in taxon
IAO_0000112: lactation SubClassOf 'only in taxon' some 'Mammalia'
definition: x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.
editor note: The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g. 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria

in taxon
type: ObjectProperty
sub property of: evolutionarily related to
property chain axiom: part of
property chain axiom: has part
property chain axiom: innervated_by
property chain axiom: overlaps
property chain axiom: continuous with
property chain axiom: connected to
property chain axiom: connects
property chain axiom: supplies
property chain axiom: regulates (processual)
property chain axiom: capable of
property chain axiom: has developmental contribution from
property chain axiom: developmentally induced by
property chain axiom: results in developmental progression of
property chain axiom: attached to
property chain axiom: has potential to develop into
property chain axiom: existence starts during
property chain axiom: existence ends during
property chain axiom: produces
property chain axiom: produced by
property chain axiom: extends_fibers_into
definition: x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.
database_cross_reference: RO:0002162
has narrow synonym: life cycle stage of
has OBO namespace: uberon
id: in_taxon
in subset: ro-eco
shorthand: in_taxon
comment: Connects a biological entity to its taxon of origin.

spatially disjoint from
type: ObjectProperty
sub property of: mereotopologically related to
definition: A is spatially_disjoint_from B if and only if they have no parts in common
editor note: There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom.
IAO_0000232: Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy
in subset: ro-eco

connected to
type: ObjectProperty
sub property of: mereotopologically related to
domain: Restriction
  on property: part of
  some values from: RO_0002577
range: Restriction
  on property: part of
  some values from: RO_0002577
property chain axiom:
  inverse of: connects
property chain axiom: connects
IAO_0000112: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b
database_cross_reference: RO:0002170
has OBO namespace: uberon
id: connected_to
shorthand: connected_to

connects
type: ObjectProperty
sub property of: mereotopologically related to
domain: independent continuant
range: Restriction
  on property: part of
  some values from: RO_0002577
IAO_0000112: The M8 connects Glasgow and Edinburgh
IAO_0000112: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system.
database_cross_reference: RO:0002176
has OBO namespace: uberon
id: connects
shorthand: connects

attached to part of
type: ObjectProperty
sub property of: mereotopologically related to
sub property of: biomechanically related to
domain: UBERON_0000061
range: UBERON_0000061
definition: a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.
database_cross_reference: RO:0002177
has OBO namespace: uberon
id: attaches_to_part_of
shorthand: attaches_to_part_of

supplies
type: ObjectProperty
sub property of: connected to
definition: Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy.
editor note: Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure
database_cross_reference: RO:0002178
has OBO namespace: uberon
id: supplies
shorthand: supplies

drains
type: ObjectProperty
sub property of: connected to
definition: Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure.
editor note: Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure
database_cross_reference: RO:0002179
has OBO namespace: uberon
id: drains
shorthand: drains

has component
type: ObjectProperty
sub property of: has part
IAO_0000114: IAO_0000125
definition: w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
editor note: The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.
IAO_0000232: For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.
RO_0001900: RO_0001901
database_cross_reference: RO:0002180
has OBO namespace: uberon
id: has_component
in subset: ro-eco
shorthand: has_component

develops from
type: ObjectProperty
sub property of: has developmental contribution from
sub property of: developmentally preceded by
inverse of: develops into
type: TransitiveProperty
domain: independent continuant
range: independent continuant
IAO_0000114: IAO_0000125
definition: x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
IAO_0000117: https://orcid.org/0000-0001-9114-8737
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228
database_cross_reference: RO:0002202
has OBO namespace: uberon
id: develops_from
shorthand: develops_from
comment: This is the transitive form of the develops from relation

develops into
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to develop into
sub property of: has potential to directly develop into
type: TransitiveProperty
IAO_0000114: IAO_0000125
definition: inverse of develops from
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228
database_cross_reference: RO:0002203
has OBO namespace: uberon
id: develops_into
in subset: RO_0002259
shorthand: develops_into

directly develops from
type: ObjectProperty
sub property of: develops from
inverse of: directly develops into
domain: Class
  union of: cell
  union of: UBERON_0010000
range: Class
  union of: cell
  union of: UBERON_0010000
definition: Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y.
database_cross_reference: RO:0002207
has_exact_synonym: has developmental precursor
has OBO namespace: uberon
id: directly_develops_from
shorthand: directly_develops_from
comment: TODO - add child relations from DOS

directly develops into
type: ObjectProperty
sub property of: develops into
definition: inverse of directly develops from
in subset: RO_0002259

regulates (processual)
type: ObjectProperty
sub property of: causally upstream of
inverse of: regulated by
type: TransitiveProperty
domain: process
range: process
property chain axiom: has effector activity
property chain axiom: ends with
property chain axiom: directly regulates
definition: p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
IAO_0000117: https://orcid.org/0000-0001-7476-6306
IAO_0000117: https://orcid.org/0000-0002-3837-8864
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000119: GO
IAO_0000232: Regulation precludes parthood; the regulatory process may not be within the regulated process.
IAO_0000589: regulates (processual)
IAO_0000600: false
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
label: regulates

negatively regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: causally upstream of, negative effect
inverse of: negatively regulated by
property chain axiom: ends with
definition: p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: negatively regulates (process to process)
RO_0004050: regulates (processual)
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

positively regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: causally upstream of, positive effect
inverse of: positively regulated by
type: TransitiveProperty
property chain axiom: negatively regulates
property chain axiom: ends with
definition: p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: positively regulates (process to process)
RO_0004049: regulates (processual)
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

capable of
type: ObjectProperty
sub property of: capable of part of
domain: independent continuant
range: process
IAO_0000112: mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
IAO_0000112: osteoclast SubClassOf 'capable of' some 'bone resorption'
definition: A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function realized in
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20123131
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/21208450
IAO_0000232: For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".
database_cross_reference: RO:0002215
has OBO namespace: uberon
id: capable_of
in subset: ro-eco
shorthand: capable_of

capable of part of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: part of
definition: c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function in
database_cross_reference: RO:0002216
has OBO namespace: uberon
id: capable_of_part_of
shorthand: capable_of_part_of

Axiom
annotated source: capable of part of
annotated property: propertyChainAxiom
annotated target: capable of
annotated target: part of
RO_0002582: true

surrounded by
type: ObjectProperty
sub property of: adjacent to
inverse of: surrounds
definition: x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x
database_cross_reference: RO:0002219
has OBO namespace: uberon
id: surrounded_by
shorthand: surrounded_by

adjacent to
type: ObjectProperty
sub property of: spatially disjoint from
type: SymmetricProperty
domain: independent continuant
range: independent continuant
IAO_0000112: A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.
IAO_0000112: The epidermis layer of a vertebrate is adjacent to the dermis.
IAO_0000112: The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies.
IAO_0000112: The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used.
definition: x adjacent to y if and only if x and y share a boundary.
editor note: This relation acts as a join point with BSPO
database_cross_reference: RO:0002220
has OBO namespace: spatial
has OBO namespace: uberon
id: adjacent_to
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
shorthand: adjacent_to

Axiom
annotated source: adjacent to
annotated property: IAO_0000112
annotated target: A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.

surrounds
type: ObjectProperty
sub property of: adjacent to
definition: inverse of surrounded by
database_cross_reference: RO:0002221
has OBO namespace: uberon
id: surrounds
in subset: RO_0002259
shorthand: surrounds

temporally related to
type: ObjectProperty
domain: occurrent
range: occurrent
IAO_0000114: IAO_0000125
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: Allen's interval algebra
IAO_0000232: Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
source: https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit
in subset: ro-eco
comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.

starts
type: ObjectProperty
sub property of: part of
sub property of: temporally related to
inverse of: starts with
definition: inverse of starts with
database_cross_reference: RO:0002223
has OBO namespace: uberon
id: starts
in subset: ro-eco
shorthand: starts

starts with
type: ObjectProperty
sub property of: has part
sub property of: temporally related to
type: TransitiveProperty
IAO_0000112: Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor
definition: x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
database_cross_reference: RO:0002224
has OBO namespace: uberon
id: starts_with
in subset: ro-eco
shorthand: starts_with

develops from part of
type: ObjectProperty
sub property of: develops from
property chain axiom: directly develops from
property chain axiom: part of
definition: x develops from part of y if and only if there exists some z such that x develops from z and z is part of y
database_cross_reference: RO:0002225
has OBO namespace: uberon
id: develops_from_part_of
shorthand: develops_from_part_of

develops in
type: ObjectProperty
sub property of: developmentally preceded by
domain: UBERON_0001062
property chain axiom: directly develops from
property chain axiom: located in
definition: x develops_in y if x is located in y whilst x is developing
database_cross_reference: RO:0002226
has OBO namespace: uberon
id: develops_in
shorthand: develops_in

ends
type: ObjectProperty
sub property of: part of
sub property of: temporally related to
inverse of: ends with
definition: inverse of ends with
database_cross_reference: RO:0002229
has OBO namespace: uberon
id: ends
in subset: ro-eco
shorthand: ends

ends with
type: ObjectProperty
sub property of: has part
sub property of: temporally related to
type: TransitiveProperty
definition: x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
database_cross_reference: RO:0002230
has OBO namespace: uberon
id: ends_with
in subset: ro-eco
shorthand: ends_with

has start location
type: ObjectProperty
sub property of: has part that occurs in
domain: process
range: independent continuant
property chain axiom: starts with
property chain axiom: occurs in
definition: x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y
in subset: ro-eco

has end location
type: ObjectProperty
sub property of: has part that occurs in
domain: process
range: independent continuant
property chain axiom: ends with
property chain axiom: occurs in
definition: x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y
in subset: ro-eco

has input
type: ObjectProperty
sub property of: has participant
inverse of: input of
domain: process
property chain axiom: starts with
IAO_0000114: IAO_0000125
definition: p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: consumes
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco

has output
type: ObjectProperty
sub property of: has participant
inverse of: output of
property chain axiom: ends with
definition: p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p.
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco

connecting branch of
type: ObjectProperty
sub property of: connected to
sub property of: in branching relationship with
inverse of: has connecting branch
IAO_0000112: In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is connecting branch of S, and B1-1 as a connecting branch of B1.
definition: b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t.
database_cross_reference: RO:0002252
has OBO namespace: uberon
id: connecting_branch_of
shorthand: connecting_branch_of

has connecting branch
type: ObjectProperty
sub property of: in branching relationship with
definition: inverse of connecting branch of
in subset: RO_0002259

has developmental contribution from
type: ObjectProperty
sub property of: developmentally preceded by
inverse of: developmentally contributes to
domain: UBERON_0001062
range: UBERON_0001062
property chain axiom: has part
IAO_0000112: Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]
IAO_0000114: IAO_0000125
definition: x has developmental contribution from y iff x has some part z such that z develops from y
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002254
has OBO namespace: uberon
id: has_developmental_contribution_from
shorthand: has_developmental_contribution_from

developmentally contributes to
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally contribute to
property chain axiom: develops into
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: inverse of has developmental contribution from
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: RO_0002259

developmentally induced by
type: ObjectProperty
sub property of: developmentally preceded by
inverse of: developmentally induces
domain: UBERON_0000465
range: UBERON_0000465
definition: t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T
IAO_0000232: We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]
database_cross_reference: RO:0002256
has OBO namespace: uberon
id: developmentally_induced_by
shorthand: developmentally_induced_by

developmentally induces
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally induce
definition: Inverse of developmentally induced by

developmentally preceded by
type: ObjectProperty
sub property of: developmentally related to
inverse of: developmentally succeeded by
domain: continuant
range: continuant
IAO_0000114: IAO_0000125
definition: Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
editor note: false
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: In general you should not use this relation to make assertions - use one of the more specific relations below this one
comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from

acts upstream of
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of
IAO_0000112: A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision.
definition: c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
in subset: valid for go gp2term

acts upstream of or within
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: enables
property chain axiom: causally upstream of or within
IAO_0000112: A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway.
definition: c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
has related synonym: affects
in subset: valid for go gp2term

developmentally replaces
type: ObjectProperty
sub property of: developmentally preceded by
definition: x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else
editor note: This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage
database_cross_reference: RO:0002285
has OBO namespace: uberon
id: developmentally_replaces
shorthand: developmentally_replaces

developmentally succeeded by
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000125
definition: Inverse of developmentally preceded by
IAO_0000117: https://orcid.org/0000-0002-6601-2165

part of developmental precursor of
type: ObjectProperty
sub property of: developmentally succeeded by
property chain axiom: part of
property chain axiom: directly develops into
IAO_0000112: 'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue

results in developmental progression of
type: ObjectProperty
sub property of: developmentally related to
domain: GO_0008150
range: UBERON_0001062
definition: p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss).
editor note: This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint.

results in development of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
IAO_0000112: every flower development (GO:0009908) results in development of some flower (PO:0009046)
definition: p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state.
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

results in formation of anatomical entity
type: ObjectProperty
sub property of: has output
sub property of: results in developmental progression of
inverse of: formed as result of
IAO_0000112: an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists.
IAO_0000112: every "endocardial cushion formation" (GO:0003272) results_in_formation_of some "endocardial cushion" (UBERON:0002062)
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

results in morphogenesis of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
IAO_0000112: an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape.
IAO_0000112: tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)
definition: The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state.
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

results in maturation of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
IAO_0000112: an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process
IAO_0000112: bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)
definition: The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity.
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

causally upstream of, positive effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, positive effect
definition: p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
RO_0004049: causally upstream of
creator: https://orcid.org/0000-0002-6601-2165
in subset: valid for go annotation extension
in subset: valid for gocam
comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y

causally upstream of, negative effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, negative effect
definition: p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
RO_0004050: causally upstream of
creator: https://orcid.org/0000-0002-6601-2165
in subset: valid for go annotation extension
in subset: valid for gocam

characteristic of part of
type: ObjectProperty
sub property of: depends on
property chain axiom: characteristic of
property chain axiom: part of
definition: q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
editor note: Because part_of is transitive, inheres in is a sub-relation of characteristic of part of
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: inheres in part of
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205
RO_0001900: RO_0001901

Axiom
annotated source: characteristic of part of
annotated property: propertyChainAxiom
annotated target: characteristic of
annotated target: part of
RO_0002582: true

results in acquisition of features of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
range: UBERON_0000061
IAO_0000112: an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast.
definition: The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

evolutionarily related to
type: ObjectProperty
definition: A relationship that holds via some environmental process
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution.

ecologically related to
type: ObjectProperty
definition: A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)
editor note: Awaiting class for domain/range constraint, see: https://github.com/OBOFoundry/Experimental-OBO-Core/issues/6
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving ecological interactions
in subset: ro-eco

confers advantage in
type: ObjectProperty
sub property of: ecologically related to
editor note: An experimental relation currently used to connect a feature possessed by an organism (e.g. anatomical structure, biological process, phenotype or quality) to a habitat or environment in which that feature is well suited, adapted or provides a reproductive advantage for the organism. For example, fins to an aquatic environment. Usually this will mean that the structure is adapted for this environment, but we avoid saying this directly - primitive forms of the structure may not have evolved specifically for that environment (for example, early wings were not necessarily adapted for an aerial environment). Note also that this is a statement about the general class of structures - not every instance of a limb need confer an advantage for a terrestrial environment, e.g. if the limb is vestigial.
database_cross_reference: RO:0002322
has OBO namespace: uberon
id: confers_advantage_in
in subset: ro-eco
shorthand: confers_advantage_in

mereotopologically related to
type: ObjectProperty
definition: A mereological relationship or a topological relationship
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
RO_0001900: RO_0001901

developmentally related to
type: ObjectProperty
definition: A relationship that holds between entities participating in some developmental process (GO:0032502)
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development

enables
type: ObjectProperty
sub property of: capable of
inverse of: enabled by
property chain axiom: has part
property chain axiom: has component activity
IAO_0000112: a particular instances of akt-2 enables some instance of protein kinase activity
definition: c enables p iff c is capable of p and c acts to execute p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: catalyzes
IAO_0000118: executes
IAO_0000118: has
IAO_0000118: is catalyzing
IAO_0000118: is executing
IAO_0000232: This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized.
in subset: valid for go gp2term

functionally related to
type: ObjectProperty
definition: A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: This is a grouping relation that collects relations used for the purpose of connecting structure and function
database_cross_reference: RO:0002328
has OBO namespace: uberon
id: functionally_related_to
shorthand: functionally_related_to

part of structure that is capable of
type: ObjectProperty
sub property of: functionally related to
property chain axiom: part of
property chain axiom: capable of
definition: this relation holds between c and p when c is part of some c', and c' is capable of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: false

Axiom
annotated source: part of structure that is capable of
annotated property: propertyChainAxiom
annotated target: part of
annotated target: capable of
is a defining property chain axiom: true

involved in
type: ObjectProperty
sub property of: participates in
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: part of
definition: c involved_in p if and only if c enables some process p', and p' is part of p
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: actively involved in
IAO_0000118: enables part of

regulates levels of
type: ObjectProperty
sub property of: functionally related to
domain: process
range: material entity
IAO_0000112: every cellular sphingolipid homeostasis process regulates_level_of some sphingolipid
definition: p regulates levels of c if p regulates some amount (PATO:0000070) of c

enabled by
type: ObjectProperty
sub property of: has participant
sub property of: functionally related to
definition: inverse of enables
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: valid for gocam

regulated by
type: ObjectProperty
sub property of: causally downstream of or within
type: TransitiveProperty
domain: process
range: process
definition: inverse of regulates
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000589: regulated by (processual)
in subset: RO_0002259

negatively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of negatively regulates
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: RO_0002259

positively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of positively regulates
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: RO_0002259

related via localization to
type: ObjectProperty
domain: process
range: continuant
definition: A relationship that holds via some process of localization
IAO_0000232: Do not use this relation directly. It is a grouping relation.

has target start location
type: ObjectProperty
sub property of: results in transport to from or in
property chain axiom: part of
definition: This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

has target end location
type: ObjectProperty
sub property of: results in transport to from or in
property chain axiom: part of
definition: This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

results in transport along
type: ObjectProperty
sub property of: related via localization to
definition: Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l

results in transport across
type: ObjectProperty
sub property of: occurs across
sub property of: results in transport to from or in
definition: Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.
in subset: valid for go ontology

results in growth of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
IAO_0000112: 'pollen tube growth' results_in growth_of some 'pollen tube'

results in transport to from or in
type: ObjectProperty
sub property of: related via localization to
IAO_0000112: 'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)

member of
type: ObjectProperty
sub property of: part of
inverse of: has member
IAO_0000112: An organism that is a member of a population of organisms
definition: is member of is a mereological relation between a item and a collection.

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
definition: has member is a mereological relation between a collection and an item.
database_cross_reference: RO:0002351
has OBO namespace: uberon
id: has_member
shorthand: has_member

input of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has input
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002352
has OBO namespace: uberon
id: input_of
in subset: RO_0002259
in subset: ro-eco
shorthand: input_of

output of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has output
database_cross_reference: RO:0002353
has OBO namespace: uberon
id: output_of
in subset: RO_0002259
in subset: ro-eco
shorthand: output_of

formed as result of
type: ObjectProperty
sub property of: output of

attached to
type: ObjectProperty
sub property of: connected to
sub property of: attached to part of
type: SymmetricProperty
definition: a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a
database_cross_reference: RO:0002371
has OBO namespace: uberon
id: attaches_to
in subset: ro-eco
shorthand: attaches_to

has muscle origin
type: ObjectProperty
sub property of: attached to
sub property of: biomechanically related to
domain: UBERON_0000061
definition: m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.
database_cross_reference: RO:0002372
has OBO namespace: uberon
id: has_muscle_origin
shorthand: has_muscle_origin

Axiom
annotated source: has muscle origin
annotated property: domain
annotated target: UBERON_0000061
comment: We need to import uberon muscle to create a stricter domain constraint

has muscle insertion
type: ObjectProperty
sub property of: attached to
sub property of: biomechanically related to
domain: UBERON_0000061
definition: m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone.
database_cross_reference: RO:0002373
has OBO namespace: uberon
id: has_muscle_insertion
shorthand: has_muscle_insertion

Axiom
annotated source: has muscle insertion
annotated property: domain
annotated target: UBERON_0000061
editor note: We need to import uberon muscle into RO to use as a stricter domain constraint

in branching relationship with
type: ObjectProperty
sub property of: mereotopologically related to
domain: material entity
range: material entity
definition: A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships
IAO_0000232: This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)

tributary of
type: ObjectProperty
sub property of: connected to
sub property of: in branching relationship with
IAO_0000112: Deschutes River tributary_of Columbia River
IAO_0000112: inferior epigastric vein tributary_of external iliac vein
definition: x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein.
IAO_0000232: This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries)
database_cross_reference: RO:0002376
has OBO namespace: uberon
id: tributary_of
in subset: ro-eco
shorthand: tributary_of

spatially coextensive with
type: ObjectProperty
sub property of: overlaps
property chain axiom: located in
property chain axiom:
  inverse of: located in
IAO_0000112: A lump of clay and a statue
definition: x spatially_coextensive_with y if and inly if x and y have the same location
IAO_0000232: This relation is added for formal completeness. It is unlikely to be used in many practical scenarios

branching part of
type: ObjectProperty
sub property of: part of
sub property of: in branching relationship with
inverse of: has branching part
range: Restriction
  on property: has characteristic
  some values from: PATO_0000402
IAO_0000112: In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S
definition: x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y
database_cross_reference: RO:0002380
has OBO namespace: uberon
id: branching_part_of
in subset: ro-eco
shorthand: branching_part_of

has developmental potential involving
type: ObjectProperty
sub property of: developmentally related to
domain: UBERON_0001062
range: UBERON_0001062
IAO_0000114: IAO_0000428
definition: x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to developmentally contribute to
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002385
has OBO namespace: uberon
id: has_potential_to_developmentally_contribute_to
shorthand: has_potential_to_developmentally_contribute_to

has potential to developmentally induce
type: ObjectProperty
sub property of: has developmental potential involving
definition: x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y

has potential to develop into
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has the potential to develop into y iff x develops into y or if x is capable of developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002387
has OBO namespace: uberon
id: has_potential_to_develop_into
shorthand: has_potential_to_develop_into
comment: This relation has a stronger meaning than merely indicating that X may develop into Y, in that the capability of developing into Y is always present, even if X does not always actually develop into Y. In particular, this means that if Y is restricted to a given taxon T, X is necessarily likewise restricted.

has potential to directly develop into
type: ObjectProperty
sub property of: has potential to develop into
IAO_0000114: IAO_0000428
definition: x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causally downstream of
type: ObjectProperty
sub property of: preceded by
sub property of: causally downstream of or within
inverse of: causally upstream of
IAO_0000114: IAO_0000428
definition: inverse of upstream of
IAO_0000117: https://orcid.org/0000-0002-6601-2165

immediately causally downstream of
type: ObjectProperty
sub property of: immediately preceded by
sub property of: causally downstream of
inverse of: immediately causally upstream of
IAO_0000114: IAO_0000428
IAO_0000117: https://orcid.org/0000-0002-6601-2165

indirectly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: indirectly regulates
type: TransitiveProperty
property chain axiom: directly positively regulates
property chain axiom: indirectly negatively regulates
definition: p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: indirectly activates
RO_0002579: positively regulates

indirectly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: indirectly regulates
type: TransitiveProperty
property chain axiom: directly negatively regulates
definition: p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: indirectly inhibits
RO_0002579: negatively regulates

causally related to
type: ObjectProperty
definition: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
editor note: This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yie…
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

Axiom
annotated source: causally related to
annotated property: definition
annotated target: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
database_cross_reference: https://en.wikipedia.org/wiki/Causality

causally upstream of
type: ObjectProperty
sub property of: precedes
sub property of: causally upstream of or within
type: TransitiveProperty
definition: p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: valid for go annotation extension
in subset: valid for gocam

immediately causally upstream of
type: ObjectProperty
sub property of: immediately precedes
sub property of: causally upstream of
definition: p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0002575: causally upstream of

causally upstream of or within
type: ObjectProperty
sub property of: causal relation between processes
inverse of: causally downstream of or within
type: TransitiveProperty
property chain axiom: part of
definition: p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
editor note: We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: influences (processual)
has related synonym: affects

causally downstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
definition: inverse of causally upstream of or within
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
in subset: RO_0002259

involved in regulation of
type: ObjectProperty
sub property of: acts upstream of
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: regulates (processual)
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' regulates some p
IAO_0000117: https://orcid.org/0000-0002-6601-2165

involved in positive regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: positively regulates
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' positively regulates some p
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0004049: involved in regulation of

involved in negative regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: negatively regulates
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
IAO_0000117: https://orcid.org/0000-0002-6601-2165
RO_0004050: involved in regulation of

involved in or involved in regulation of
type: ObjectProperty
sub property of: acts upstream of or within
sub property of: functionally related to
sub property of: causal agent in process
definition: c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
editor note: OWL does not allow defining object properties via a Union
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: involved in or reguates

contributes to morphology of
type: ObjectProperty
sub property of: overlaps
definition: p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm.
database_cross_reference: RO:0002433
has OBO namespace: uberon
id: contributes_to_morphology_of
shorthand: contributes_to_morphology_of

interacts with
type: ObjectProperty
type: SymmetricProperty
domain: material entity
range: material entity
definition: A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
editor note: Considering relabeling as 'pairwise interacts with'
editor note: This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules.
has_exact_synonym: in pairwise interaction with
in subset: ro-eco

molecularly interacts with
type: ObjectProperty
sub property of: interacts with
type: SymmetricProperty
definition: An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: binds
IAO_0000118: molecularly binds with

phosphorylates
type: ObjectProperty
sub property of: molecularly interacts with
editor note: Axiomatization to GO to be added later
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.

directly regulates activity of
type: ObjectProperty
sub property of: molecularly interacts with
sub property of: regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: regulates (processual)
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431
has_exact_synonym: molecularly controls

directly negatively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly negatively regulates
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431
IAO_0000118: directly inhibits
has_exact_synonym: molecularly decreases activity of

directly positively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly positively regulates
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431
IAO_0000118: directly activates
has_exact_synonym: molecularly increases activity of

helper property (not for use in curation)
type: ObjectProperty
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning.

composed primarily of
type: ObjectProperty
sub property of: has part
domain: material entity
range: material entity
IAO_0000112: 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'
definition: x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
database_cross_reference: RO:0002473
has OBO namespace: uberon
id: composed_primarily_of
in subset: ro-eco
shorthand: composed_primarily_of

has part that occurs in
type: ObjectProperty
domain: occurrent
range: independent continuant
definition: p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
in subset: ro-eco

is kinase activity
type: ObjectProperty
sub property of: molecular interaction relation helper property
IAO_0000117: https://orcid.org/0000-0002-6601-2165

receives input from
type: ObjectProperty
sub property of: connected to
inverse of: sends output to
editor note: See notes for inverse relation

sends output to
type: ObjectProperty
sub property of: connected to
editor note: This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in.

relation between physical entity and a process or stage
type: ObjectProperty
domain: independent continuant
range: occurrent
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage.

existence starts during
type: ObjectProperty
sub property of: existence overlaps
sub property of: existence starts during or after
property chain axiom: part of
definition: x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002488
has OBO namespace: uberon
id: existence_starts_during
shorthand: existence_starts_during

existence starts with
type: ObjectProperty
sub property of: existence starts during
definition: x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y).
database_cross_reference: RO:0002489
has OBO namespace: uberon
id: existence_starts_with
shorthand: existence_starts_with

existence overlaps
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
definition: x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence starts and ends during
type: ObjectProperty
sub property of: existence starts during
sub property of: existence ends during
definition: x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)
database_cross_reference: RO:0002491
has_exact_synonym: exists during
has OBO namespace: uberon
id: existence_starts_and_ends_during
shorthand: existence_starts_and_ends_during
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends during
type: ObjectProperty
sub property of: existence overlaps
sub property of: existence ends during or before
property chain axiom: part of
definition: x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002492
has OBO namespace: uberon
id: existence_ends_during
shorthand: existence_ends_during
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends with
type: ObjectProperty
sub property of: existence ends during
definition: x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y).
database_cross_reference: RO:0002493
has OBO namespace: uberon
id: existence_ends_with
shorthand: existence_ends_with
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

transformation of
type: ObjectProperty
sub property of: develops from
type: TransitiveProperty
definition: x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships
database_cross_reference: RO:0002494
has OBO namespace: uberon
id: transformation_of
shorthand: transformation_of

immediate transformation of
type: ObjectProperty
sub property of: directly develops from
sub property of: transformation of
definition: x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t
database_cross_reference: RO:0002495
has OBO namespace: uberon
id: immediate_transformation_of
shorthand: immediate_transformation_of

existence starts during or after
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
property chain axiom: part of
property chain axiom: developmentally preceded by
property chain axiom: preceded by
property chain axiom: simultaneous with
definition: x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002496
has OBO namespace: uberon
id: existence_starts_during_or_after
shorthand: existence_starts_during_or_after
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends during or before
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
property chain axiom: part of
property chain axiom: developmentally succeeded by
property chain axiom: precedes
property chain axiom: simultaneous with
definition: x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002497
has OBO namespace: uberon
id: existence_ends_during_or_before
shorthand: existence_ends_during_or_before
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

causal agent in process
type: ObjectProperty
sub property of: causal relation between material entity and a process
inverse of: process has causal agent
definition: A relationship between a material entity and a process where the material entity has some causal role that influences the process
IAO_0000119: causal-relations

causal relation between processes
type: ObjectProperty
sub property of: causally related to
domain: occurrent
range: occurrent
definition: p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

depends on
type: ObjectProperty
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causal relation between entities
type: ObjectProperty
sub property of: causally related to
domain: continuant
range: continuant
editor note: The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

has skeleton
type: ObjectProperty
sub property of: has part
inverse of: skeleton of
type: AsymmetricProperty
type: IrreflexiveProperty
domain: UBERON_0000061
range: UBERON_0000465
IAO_0000112: Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'
definition: A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision.
IAO_0000232: The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell).
database_cross_reference: RO:0002551
has OBO namespace: uberon
id: has_skeleton
shorthand: has_skeleton

Axiom
annotated source: has skeleton
annotated property: range
annotated target: UBERON_0000465
editor note: This should be to a more restricted class, but not the Uberon class may be too restricted since it is a composition-based definition of skeleton rather than functional.

causally influenced by
type: ObjectProperty
sub property of: causal relation between entities
inverse of: causally influences
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: causally influenced by (entity-centric)

interaction relation helper property
type: ObjectProperty
sub property of: helper property (not for use in curation)
IAO_0000117: https://orcid.org/0000-0002-6601-2165

molecular interaction relation helper property
type: ObjectProperty
sub property of: interaction relation helper property
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causally influences
type: ObjectProperty
sub property of: causal relation between entities
domain: continuant
range: continuant
property chain axiom: enables
property chain axiom: causally upstream of
property chain axiom: has input
property chain axiom: enabled by
definition: The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0003-4639-4431
IAO_0000119: causal-relations
IAO_0000589: causally influences (entity-centric)

biomechanically related to
type: ObjectProperty
sub property of: functionally related to
domain: UBERON_0000061
range: UBERON_0000061
definition: A relation that holds between elements of a musculoskeletal system or its analogs.
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes.

has muscle antagonist
type: ObjectProperty
sub property of: biomechanically related to
definition: m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position.
database_cross_reference: RO:0002568
has OBO namespace: uberon
id: has_muscle_antagonist
shorthand: has_muscle_antagonist

has branching part
type: ObjectProperty
sub property of: has part
sub property of: in branching relationship with
type: TransitiveProperty
definition: inverse of branching part of
database_cross_reference: RO:0002569
has OBO namespace: uberon
id: has_branching_part
in subset: RO_0002259
in subset: ro-eco
shorthand: has_branching_part

conduit for
type: ObjectProperty
sub property of: overlaps
domain: material entity
range: material entity
definition: x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x.
IAO_0000232: This relation holds between a thing with a 'conduit' (e.g. a bone foramen) and a 'conduee' (for example, a nerve) such that at the time the relationship holds, the conduee has two ends sticking out either end of the conduit. It should therefore note be used for objects that move through the conduit but whose spatial extent does not span the passage. For example, it would not be used for a mountain that contains a long tunnel through which trains pass. Nor would we use it for a digestive tract and objects such as food that pass through.
database_cross_reference: RO:0002570
has OBO namespace: uberon
id: conduit_for
in subset: ro-eco
shorthand: conduit_for

lumen of
type: ObjectProperty
sub property of: part of
range: material entity
definition: x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull.
database_cross_reference: RO:0002571
has OBO namespace: uberon
id: lumen_of
in subset: ro-eco
shorthand: lumen_of

luminal space of
type: ObjectProperty
sub property of: lumen of
domain: immaterial entity
definition: s is luminal space of x iff s is lumen_of x and s is an immaterial entity
database_cross_reference: RO:0002572
has OBO namespace: uberon
id: luminal_space_of
in subset: ro-eco
shorthand: luminal_space_of

skeleton of
type: ObjectProperty
sub property of: part of
domain: UBERON_0000061
range: UBERON_0000061
definition: inverse of has skeleton
database_cross_reference: RO:0002576
has OBO namespace: uberon
id: skeleton_of
in subset: RO_0002259
shorthand: skeleton_of

directly regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: immediately causally upstream of
definition: p directly regulates q iff p is immediately causally upstream of q and p regulates q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000589: directly regulates (processual)
RO_0002575: regulates (processual)
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

has part structure that is capable of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal relation between material entity and a process
property chain axiom: has part
property chain axiom: capable of
IAO_0000112: gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
definition: s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
IAO_0000117: https://orcid.org/0000-0002-6601-2165

results in breakdown of
type: ObjectProperty
sub property of: has input
definition: p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p

results in assembly of
type: ObjectProperty
sub property of: results in formation of anatomical entity
sub property of: results in organization of
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

results in disassembly of
type: ObjectProperty
sub property of: results in breakdown of
sub property of: results in organization of

results in organization of
type: ObjectProperty
sub property of: results in changes to anatomical or cellular structure
definition: p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c

causal relation between material entity and a process
type: ObjectProperty
sub property of: causally related to
domain: material entity
range: process
definition: A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
editor note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations

capable of regulating
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: regulates (processual)
IAO_0000112: pyrethroid -> growth
definition: Holds between c and p if and only if c is capable of some activity a, and a regulates p.
IAO_0000119: causal-relations

capable of negatively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: negatively regulates
definition: Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
IAO_0000119: causal-relations

capable of positively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: positively regulates
IAO_0000112: renin -> arteriolar smooth muscle contraction
definition: Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
IAO_0000119: causal-relations

process has causal agent
type: ObjectProperty
sub property of: causally related to
definition: Inverse of 'causal agent in process'
IAO_0000119: causal-relations

directly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: directly regulates
definition: p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.
IAO_0000119: causal-relations
IAO_0000589: directly positively regulates (process to process)
RO_0004049: directly regulates
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

directly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: directly regulates
definition: p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.
IAO_0000119: causal-relations
IAO_0000589: directly negatively regulates (process to process)
RO_0004050: directly regulates
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

produces
type: ObjectProperty
inverse of: produced by
domain: material entity
range: material entity
property chain axiom:
  inverse of: occurs in
property chain axiom: has output
definition: a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.
database_cross_reference: RO:0003000
has OBO namespace: uberon
id: produces
in subset: ro-eco
shorthand: produces
comment: Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue.

produced by
type: ObjectProperty
domain: material entity
range: material entity
definition: a produced_by b iff some process that occurs_in b has_output a.
database_cross_reference: RO:0003001
has OBO namespace: uberon
id: produced_by
in subset: ro-eco
shorthand: produced_by

has primary input or output
type: ObjectProperty
sub property of: has participant
definition: p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-12-13T11:26:17Z
in subset: valid for go ontology

has primary output
type: ObjectProperty
sub property of: has output
sub property of: has primary input or output
definition: p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-12-13T11:26:32Z
in subset: valid for go ontology

Axiom
annotated source: has primary output
annotated property: definition
annotated target: p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.
database_cross_reference: https://orcid.org/0000-0002-6601-2165
database_cross_reference: GOC:dph
database_cross_reference: GOC:kva
database_cross_reference: GOC:pt
comment: PMID:27812932

has primary input
type: ObjectProperty
sub property of: has input
sub property of: has primary input or output
definition: p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-12-13T11:26:56Z
in subset: valid for go ontology

Axiom
annotated source: has primary input
annotated property: definition
annotated target: p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.
database_cross_reference: https://orcid.org/0000-0002-6601-2165
database_cross_reference: GOC:dph
database_cross_reference: GOC:kva
database_cross_reference: GOC:pt
comment: PMID:27812932

enables subfunction
type: ObjectProperty
sub property of: functionally related to
property chain axiom: enables
property chain axiom: has part
definition: Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-01-25T23:20:13Z

acts upstream of or within, positive effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, positive effect
RO_0004049: acts upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-01-26T23:49:30Z
in subset: valid for go gp2term

acts upstream of or within, negative effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, negative effect
RO_0004050: acts upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-01-26T23:49:51Z
in subset: valid for go gp2term

acts upstream of, positive effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, positive effect
property chain axiom: enables
property chain axiom: causally upstream of, positive effect
definition: c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
RO_0004049: acts upstream of
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-01-26T23:53:14Z
in subset: valid for go gp2term

acts upstream of, negative effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, negative effect
property chain axiom: enables
property chain axiom: causally upstream of, negative effect
definition: c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
RO_0004050: acts upstream of
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-01-26T23:53:22Z
in subset: valid for go gp2term

causally upstream of or within, negative effect
type: ObjectProperty
sub property of: causally upstream of or within
RO_0004050: causally upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-03-13T23:55:05Z

causally upstream of or within, positive effect
type: ObjectProperty
sub property of: causally upstream of or within
RO_0004049: causally upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-03-13T23:55:19Z

regulates activity of
type: ObjectProperty
sub property of: causally influences
domain: material entity
range: material entity
definition: The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
IAO_0000117: https://orcid.org/0000-0003-4639-4431

acts on population of
type: ObjectProperty
sub property of: has participant
definition: p acts on population of c iff c' is a collection, has members of type c, and p has participant c
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-06-08T17:21:33Z
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

results in fusion of
type: ObjectProperty
sub property of: results in organization of
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2021-02-26T07:28:29Z
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

indirectly causally upstream of
type: ObjectProperty
sub property of: causally upstream of
definition: p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2022-09-26T06:07:17Z

indirectly regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: indirectly causally upstream of
definition: p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q.
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2022-09-26T06:08:01Z

has characterizing marker set
type: ObjectProperty
domain: cell
IAO_0000112: 'Lamp5-like Egln3_1 primary motor cortex GABAergic interneuron (Mus musculus)' subClass_of: has_characterizing_marker_set some 'NS forest marker set of Lamp5-like Egln3_1 MOp (Mouse).'; NS forest marker set of Lamp5-like Egln3_1 SubClass_of: ('has part' some 'Mouse Fbn2') and ('has part' some 'Mouse Chrna7') and ('has part' some 'Mouse Fam19a1').
IAO_0000112: transcriptomically defined cell type X subClass_of: (has_characterizing_marker_set some S1); S1 has_part some gene 1, S1 has_part some gene 2, S1 has_part some gene 3.
definition: A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type.
editor note: C has_characterizing_marker_set y iff: C is a cell type and y is a collection of genes or proteins whose expression is sufficient to distinguish cell type C from most or all other cell types.
IAO_0000232: This relation is not meant for cases where set of genes/proteins are only useful as markers in some specific context - e.g. in some specific location. In these cases it is recommended to make a more specific cell class restricted to the relevant context.
contributor: https://orcid.org/0000-0001-7258-9596
has_exact_synonym: has marker gene combination
has_exact_synonym: has marker signature set

has cross section
type: ObjectProperty
definition: s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.
comment: Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.

Axiom
annotated source: has cross section
annotated property: definition
annotated target: s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

device utilizes material
type: ObjectProperty
property chain axiom: capable of
property chain axiom: has input
IAO_0000112: A diagnostic testing device utilizes a specimen.
definition: X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
IAO_0000232: A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.
IAO_0000232: See github ticket https://github.com/oborel/obo-relations/issues/497
contributor: https://orcid.org/0000-0001-9625-1899
contributor: https://orcid.org/0000-0003-2620-0345
creation date: 2021-11-08T12:00:00Z
has broad synonym: utilizes

regulates characteristic
type: ObjectProperty
sub property of: causally related to
domain: process
range: PATO_0000001
property chain axiom: regulates (processual)
definition: A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.
contributor: https://orcid.org/0000-0002-8688-6599

positively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
property chain axiom: positively regulates
definition: A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.
contributor: https://orcid.org/0000-0002-8688-6599

negatively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
property chain axiom: negatively regulates
property chain axiom: positively regulates characteristic
property chain axiom: positively regulates
definition: A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.
contributor: https://orcid.org/0000-0002-8688-6599

vessel supplies blood to
type: ObjectProperty
sub property of: supplies
domain: UBERON_0001981
range: UBERON_0000061
IAO_0000112: brachial artery vessel supplies blood to brachialis muscle
definition: x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-02-01T10:09:22Z
database_cross_reference: RO:0020101
has OBO namespace: uberon
id: vessel_supplies_blood_to
shorthand: vessel_supplies_blood_to

vessel drains blood from
type: ObjectProperty
sub property of: drains
domain: UBERON_0001981
range: UBERON_0000061
IAO_0000112: cystic vein vessel drains blood from gallbladder
definition: x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-02-01T10:09:41Z
database_cross_reference: RO:0020102
has OBO namespace: uberon
id: vessel_drains_blood_from
shorthand: vessel_drains_blood_from

is anatomical entity
type: ObjectProperty
domain: UBERON_0001062
definition: This property only applies to anatomical entities.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-10-29T09:55:07Z

results in changes to anatomical or cellular structure
type: ObjectProperty
sub property of: has participant
definition: p has anatomical participant c iff p has participant c, and c is an anatomical entity
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-09-26T01:08:58Z

anteriorly connected to
type: ObjectProperty
sub property of: posterior to
sub property of: connected to
sub property of: transitively anteriorly connected to
definition: x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y.
has OBO namespace: uberon
id: anteriorly_connected_to

Axiom
annotated source: anteriorly connected to
annotated property: definition
annotated target: x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

channel for
type: ObjectProperty
domain: UBERON_0004111
range: UBERON_0000463
has broad synonym: carries
has OBO namespace: uberon
id: channel_for

channels_from
type: ObjectProperty
type: TransitiveProperty
has OBO namespace: uberon
id: channels_from

channels_into
type: ObjectProperty
type: TransitiveProperty
has OBO namespace: uberon
id: channels_into

distally connected to
type: ObjectProperty
sub property of: proximal to
sub property of: connected to
sub property of: transitively distally connected to
inverse of: proximally connected to
definition: x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y.
has OBO namespace: uberon
id: distally_connected_to

Axiom
annotated source: distally connected to
annotated property: definition
annotated target: x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

extends_fibers_into
type: ObjectProperty
sub property of: connected to
type: SymmetricProperty
definition: X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y
has OBO namespace: uberon
id: extends_fibers_into

Axiom
annotated source: extends_fibers_into
annotated property: definition
annotated target: X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y
database_cross_reference: https://orcid.org/0000-0002-7073-9172

filtered through
type: ObjectProperty
definition: Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity.
has OBO namespace: uberon
id: filtered_through
comment: Relationship between a fluid and a filtration barrier, where the portion of fluid arises as a transformation of another portion of fluid on the other side of the barrier, with larger particles removed

indirectly_supplies
type: ObjectProperty
type: TransitiveProperty
property chain axiom: has branching part
property chain axiom: supplies
definition: a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s.
editor note: add to RO
has OBO namespace: uberon
id: indirectly_supplies

layer part of
type: ObjectProperty
sub property of: part of
has OBO namespace: uberon
id: layer_part_of

posteriorly connected to
type: ObjectProperty
sub property of: anterior to
sub property of: connected to
definition: x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y.
has OBO namespace: uberon
id: posteriorly_connected_to

Axiom
annotated source: posteriorly connected to
annotated property: definition
annotated target: x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

protects
type: ObjectProperty
has OBO namespace: uberon
id: protects

proximally connected to
type: ObjectProperty
sub property of: distal to
sub property of: connected to
sub property of: transitively proximally connected to
definition: x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y.
has OBO namespace: uberon
id: proximally_connected_to

Axiom
annotated source: proximally connected to
annotated property: definition
annotated target: x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

site_of
type: ObjectProperty
definition: c site_of p if c is the bearer of a disposition that is realized by a process that has p as part.
has OBO namespace: uberon
has related synonym: capable_of_has_part
id: site_of

subdivision of
type: ObjectProperty
has OBO namespace: uberon
id: subdivision_of
comment: placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B

transitively anteriorly connected to
type: ObjectProperty
type: TransitiveProperty
has OBO namespace: uberon
id: transitively_anteriorly_connected_to

transitively distally connected to
type: ObjectProperty
type: TransitiveProperty
has OBO namespace: uberon
id: transitively_distally_connected_to

transitively proximally connected to
type: ObjectProperty
type: TransitiveProperty
has OBO namespace: uberon
id: transitively_proximally_connected_to

entity
type: Class
BFO_0000179: entity
BFO_0000180: Entity
IAO_0000112: Julius Caesar
IAO_0000112: Verdi’s Requiem
IAO_0000112: the Second World War
IAO_0000112: your body mass index
editor note: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
editor note: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
IAO_0000600: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])

Axiom
annotated source: entity
annotated property: editor note
annotated target: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000004
comment: per discussion with Barry Smith

Axiom
annotated source: entity
annotated property: IAO_0000600
annotated target: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/001-001

continuant
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: continuant
disjoint with: occurrent
disjoint with: Restriction
  on property: part of
  some values from: occurrent
BFO_0000179: continuant
BFO_0000180: Continuant
definition: An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
editor note: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
editor note: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
IAO_0000600: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
IAO_0000601: if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
IAO_0000601: if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
IAO_0000601: if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
IAO_0000602: (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
IAO_0000602: (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
IAO_0000602: (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
IAO_0000602: (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]

Axiom
annotated source: continuant
annotated property: editor note
annotated target: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/0000007

Axiom
annotated source: continuant
annotated property: IAO_0000600
annotated target: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: IAO_0000601
annotated target: if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: IAO_0000601
annotated target: if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: IAO_0000601
annotated target: if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/011-002

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: IAO_0000602
annotated target: (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/011-002

occurrent
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: occurrent
disjoint with: Restriction
  on property: part of
  some values from: continuant
definition: An entity that has temporal parts and that happens, unfolds or develops through time.
editor note: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region
editor note: BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.
IAO_0000589: processual entity (BFO)

independent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: independent continuant
disjoint with: specifically dependent continuant
BFO_0000179: ic
BFO_0000180: IndependentContinuant
IAO_0000112: a chair
IAO_0000112: a heart
IAO_0000112: a leg
IAO_0000112: a molecule
IAO_0000112: a spatial region
IAO_0000112: an atom
IAO_0000112: an orchestra.
IAO_0000112: an organism
IAO_0000112: the bottom right portion of a human torso
IAO_0000112: the interior of your mouth
definition: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
IAO_0000589: anatomical entity (BFO)
IAO_0000601: For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
IAO_0000601: For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
IAO_0000602: (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
IAO_0000602: (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
IAO_0000602: (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
comment: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.

Axiom
annotated source: independent continuant
annotated property: definition
annotated target: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/017-002

Axiom
annotated source: independent continuant
annotated property: IAO_0000601
annotated target: For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: IAO_0000601
annotated target: For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: IAO_0000602
annotated target: (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: IAO_0000602
annotated target: (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: IAO_0000602
annotated target: (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/017-002

spatial region
type: Class
subclass of: immaterial entity
editor note: BFO 2 Reference: Spatial regions do not participate in processes.

process
type: Class
subclass of: occurrent
IAO_0000112: a process of cell-division, \ a beating of the heart
IAO_0000112: a process of meiosis
IAO_0000112: a process of sleeping
IAO_0000112: the course of a disease
IAO_0000112: the flight of a bird
IAO_0000112: the life of an organism
IAO_0000112: your process of aging.
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
editor note: BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)
comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.

disposition
type: Class
subclass of: realizable entity
disjoint with: role

realizable entity
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
  on property: part of
  all values from: realizable entity
disjoint with: quality
IAO_0000112: the disposition of this piece of metal to conduct electricity.
IAO_0000112: the disposition of your blood to coagulate
IAO_0000112: the function of your reproductive organs
IAO_0000112: the role of being a doctor
IAO_0000112: the role of this boundary to delineate where Utah and Colorado meet
definition: A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.

quality
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
  on property: part of
  all values from: quality
IAO_0000112: the ambient temperature of this portion of air
IAO_0000112: the color of a tomato
IAO_0000112: the length of the circumference of your waist
IAO_0000112: the mass of this piece of gold.
IAO_0000112: the shape of your nose
IAO_0000112: the shape of your nostril

specifically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: specifically dependent continuant
IAO_0000112: Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
IAO_0000112: of one-sided specifically dependent continuants: the mass of this tomato
IAO_0000112: of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
IAO_0000112: the disposition of this fish to decay
IAO_0000112: the function of this heart: to pump blood
IAO_0000112: the mutual dependence of proton donors and acceptors in chemical reactions [79
IAO_0000112: the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
IAO_0000112: the pink color of a medium rare piece of grilled filet mignon at its center
IAO_0000112: the role of being a doctor
IAO_0000112: the shape of this hole.
IAO_0000112: the smell of this portion of mozzarella
definition: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.

role
type: Class
subclass of: realizable entity
IAO_0000112: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
IAO_0000112: the priest role
IAO_0000112: the role of a boundary to demarcate two neighboring administrative territories
IAO_0000112: the role of a building in serving as a military target
IAO_0000112: the role of a stone in marking a property boundary
IAO_0000112: the role of subject in a clinical trial
IAO_0000112: the student role
definition: A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
editor note: BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.

function
type: Class
subclass of: disposition

material entity
type: Class
subclass of: independent continuant
disjoint with: immaterial entity
disjoint with: Restriction
  on property: part of
  some values from: immaterial entity
BFO_0000179: material
BFO_0000180: MaterialEntity
IAO_0000112: a flame
IAO_0000112: a forest fire
IAO_0000112: a human being
IAO_0000112: a hurricane
IAO_0000112: a photon
IAO_0000112: a puff of smoke
IAO_0000112: a sea wave
IAO_0000112: a tornado
IAO_0000112: an aggregate of human beings.
IAO_0000112: an energy wave
IAO_0000112: an epidemic
IAO_0000112: the undetached arm of a human being
definition: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
editor note: BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
editor note: BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
editor note: BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
editor note: Elucidation: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
IAO_0000600: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
IAO_0000601: Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
IAO_0000601: every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
IAO_0000602: (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
IAO_0000602: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
IAO_0000602: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]

Axiom
annotated source: material entity
annotated property: IAO_0000600
annotated target: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: IAO_0000601
annotated target: Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/020-002

Axiom
annotated source: material entity
annotated property: IAO_0000601
annotated target: every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: IAO_0000602
annotated target: (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: IAO_0000602
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: IAO_0000602
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
IAO_0010000: http://purl.obolibrary.org/obo/bfo/axiom/020-002

immaterial entity
type: Class
subclass of: independent continuant
disjoint with: Restriction
  on property: has part
  some values from: material entity
editor note: BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10

anatomical entity
type: Class
definition: Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
has OBO namespace: spatial
id: CARO:0000000

Axiom
annotated source: anatomical entity
annotated property: definition
annotated target: Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
database_cross_reference: CARO:MAH

electron
type: Class
subclass of: lepton
definition: Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
database_cross_reference: KEGG:C05359
database_cross_reference: PMID:21614077
database_cross_reference: Wikipedia:Electron
has_exact_synonym: electron
has OBO namespace: chebi_ontology
has related synonym: Elektron
has related synonym: beta
has related synonym: beta(-)
has related synonym: beta-particle
has related synonym: e
has related synonym: e(-)
has related synonym: e-
has related synonym: negatron
id: CHEBI:10545
in subset: 3 STAR

Axiom
annotated source: electron
annotated property: database_cross_reference
annotated target: PMID:21614077
source: Europe PMC

Axiom
annotated source: electron
annotated property: has_exact_synonym
annotated target: electron
database_cross_reference: ChEBI

Axiom
annotated source: electron
annotated property: has_exact_synonym
annotated target: electron
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: electron
annotated property: has_exact_synonym
annotated target: electron
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: Elektron
database_cross_reference: ChEBI

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: beta
database_cross_reference: IUPAC

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: beta(-)
database_cross_reference: ChEBI

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: beta-particle
database_cross_reference: IUPAC

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: e
database_cross_reference: IUPAC

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: e(-)
database_cross_reference: UniProt

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: e-
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: electron
annotated property: hasRelatedSynonym
annotated target: negatron
database_cross_reference: IUPAC

dicarboxylic acids and O-substituted derivatives
type: Class
subclass of: carbonyl compound
definition: A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens.
has OBO namespace: chebi_ontology
has related synonym: dicarboxylic acids and derivatives
id: CHEBI:131927
in subset: 3 STAR

Axiom
annotated source: dicarboxylic acids and O-substituted derivatives
annotated property: hasRelatedSynonym
annotated target: dicarboxylic acids and derivatives
database_cross_reference: ChEBI

hyaluronate
type: Class
subclass of: polyanionic polymer
subclass of: carbohydrate acid derivative anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: hyaluronic acid
definition: A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3.
has OBO namespace: chebi_ontology
has related synonym: hyaluronan
has related synonym: hyaluronate polyanion
id: CHEBI:132153
in subset: 3 STAR

Axiom
annotated source: hyaluronate
annotated property: hasRelatedSynonym
annotated target: hyaluronan
database_cross_reference: UniProt

Axiom
annotated source: hyaluronate
annotated property: hasRelatedSynonym
annotated target: hyaluronate polyanion
database_cross_reference: ChEBI

5beta steroid
type: Class
subclass of: steroid
definition: Any steroid that has beta-configuration at position 5.
has OBO namespace: chebi_ontology
has related synonym: 5beta steroids
has related synonym: 5beta-steroid
has related synonym: 5beta-steroids
id: CHEBI:136889
in subset: 3 STAR

Axiom
annotated source: 5beta steroid
annotated property: hasRelatedSynonym
annotated target: 5beta steroids
database_cross_reference: ChEBI

Axiom
annotated source: 5beta steroid
annotated property: hasRelatedSynonym
annotated target: 5beta-steroid
database_cross_reference: ChEBI

Axiom
annotated source: 5beta steroid
annotated property: hasRelatedSynonym
annotated target: 5beta-steroids
database_cross_reference: ChEBI

inorganic acid
type: Class
subclass of: Bronsted acid
definition: A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
database_cross_reference: Wikipedia:Mineral_acid
has OBO namespace: chebi_ontology
has related synonym: inorganic acids
has related synonym: mineral acid
has related synonym: mineral acids
id: CHEBI:138103
in subset: 3 STAR

Axiom
annotated source: inorganic acid
annotated property: hasRelatedSynonym
annotated target: inorganic acids
database_cross_reference: ChEBI

Axiom
annotated source: inorganic acid
annotated property: hasRelatedSynonym
annotated target: mineral acid
database_cross_reference: ChEBI

Axiom
annotated source: inorganic acid
annotated property: hasRelatedSynonym
annotated target: mineral acids
database_cross_reference: ChEBI

bile acids
type: Class
subclass of: monocarboxylic acid
subclass of: hydroxy steroid
subclass of: cholanoid
definition: Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration.
has OBO namespace: chebi_ontology
id: CHEBI:138366
in subset: 3 STAR

gas molecular entity
type: Class
subclass of: main group molecular entity
definition: Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/Gas
has OBO namespace: chebi_ontology
has related synonym: gas molecular entities
has related synonym: gaseous molecular entities
has related synonym: gaseous molecular entity
id: CHEBI:138675
in subset: 3 STAR

Axiom
annotated source: gas molecular entity
annotated property: hasRelatedSynonym
annotated target: gas molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: gas molecular entity
annotated property: hasRelatedSynonym
annotated target: gaseous molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: gas molecular entity
annotated property: hasRelatedSynonym
annotated target: gaseous molecular entity
database_cross_reference: ChEBI

carbamate
type: Class
subclass of: amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbamic acid
database_cross_reference: Beilstein:3903503
database_cross_reference: CAS:302-11-4
database_cross_reference: Gmelin:239604
has_exact_synonym: carbamate
has OBO namespace: chebi_ontology
has related synonym: Carbamat
has related synonym: Karbamat
has related synonym: carbamate ion
has related synonym: carbamic acid, ion(1-)
id: CHEBI:13941
in subset: 3 STAR

Axiom
annotated source: carbamate
annotated property: database_cross_reference
annotated target: Beilstein:3903503
source: Beilstein

Axiom
annotated source: carbamate
annotated property: database_cross_reference
annotated target: CAS:302-11-4
source: ChemIDplus

Axiom
annotated source: carbamate
annotated property: database_cross_reference
annotated target: Gmelin:239604
source: Gmelin

Axiom
annotated source: carbamate
annotated property: has_exact_synonym
annotated target: carbamate
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbamate
annotated property: has_exact_synonym
annotated target: carbamate
database_cross_reference: UniProt

Axiom
annotated source: carbamate
annotated property: hasRelatedSynonym
annotated target: Carbamat
database_cross_reference: ChEBI

Axiom
annotated source: carbamate
annotated property: hasRelatedSynonym
annotated target: Karbamat
database_cross_reference: ChEBI

Axiom
annotated source: carbamate
annotated property: hasRelatedSynonym
annotated target: carbamate ion
database_cross_reference: ChemIDplus

Axiom
annotated source: carbamate
annotated property: hasRelatedSynonym
annotated target: carbamic acid, ion(1-)
database_cross_reference: ChemIDplus

24G7 epitope
type: Class
subclass of: independent continuant
subclass of: group
subclass of: Restriction
  on property: has role
  some values from: epitope
definition: An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22.
has OBO namespace: chebi_ontology
id: CHEBI:142163
in subset: 3 STAR

acceptor
type: Class
subclass of: chemical role
definition: A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
has alternative id: CHEBI:13699
has alternative id: CHEBI:2377
database_cross_reference: KEGG:C00028
database_cross_reference: KEGG:C16722
has_exact_synonym: Acceptor
has OBO namespace: chebi_ontology
has related synonym: A
has related synonym: Akzeptor
has related synonym: Hydrogen-acceptor
has related synonym: Oxidized donor
has related synonym: accepteur
id: CHEBI:15339
in subset: 3 STAR

Axiom
annotated source: acceptor
annotated property: has_exact_synonym
annotated target: Acceptor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: hasRelatedSynonym
annotated target: A
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: hasRelatedSynonym
annotated target: Akzeptor
database_cross_reference: ChEBI

Axiom
annotated source: acceptor
annotated property: hasRelatedSynonym
annotated target: Hydrogen-acceptor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: hasRelatedSynonym
annotated target: Oxidized donor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: hasRelatedSynonym
annotated target: accepteur
database_cross_reference: ChEBI

acetylcholine
type: Class
subclass of: independent continuant
subclass of: acylcholine
subclass of: acetate ester
subclass of: Restriction
  on property: has role
  some values from: hormone
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: vasodilator agent
subclass of: Restriction
  on property: has role
  some values from: muscarinic agonist
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
definition: Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter.
has alternative id: CHEBI:12686
has alternative id: CHEBI:13715
has alternative id: CHEBI:22197
has alternative id: CHEBI:2416
has alternative id: CHEBI:40559
database_cross_reference: Beilstein:1764436
database_cross_reference: CAS:51-84-3
database_cross_reference: DrugBank:DB03128
database_cross_reference: Drug_Central:65
database_cross_reference: Gmelin:326108
database_cross_reference: KEGG:C01996
database_cross_reference: LINCS:LSM-5888
database_cross_reference: PDBeChem:ACH
database_cross_reference: PMID:14764638
database_cross_reference: PMID:15014918
database_cross_reference: PMID:15231705
database_cross_reference: PMID:15361288
database_cross_reference: PMID:18050502
database_cross_reference: PMID:18407448
database_cross_reference: PMID:19255787
database_cross_reference: PMID:20963497
database_cross_reference: PMID:21130809
database_cross_reference: PMID:21246223
database_cross_reference: PMID:21545631
database_cross_reference: PMID:21601579
database_cross_reference: Wikipedia:Acetylcholine
has_exact_synonym: 2-acetyloxy-N,N,N-trimethylethanaminium
has_exact_synonym: ACETYLCHOLINE
has_exact_synonym: Acetylcholine
has_exact_synonym: acetylcholine
has OBO namespace: chebi_ontology
has related synonym: ACh
has related synonym: Azetylcholin
has related synonym: O-Acetylcholine
has related synonym: choline acetate
id: CHEBI:15355
in subset: 3 STAR

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: Beilstein:1764436
source: ChemIDplus

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: CAS:51-84-3
source: ChemIDplus

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: CAS:51-84-3
source: KEGG COMPOUND

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: Drug_Central:65
source: DrugCentral

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: Gmelin:326108
source: Gmelin

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:14764638
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:15014918
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:15231705
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:15361288
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:18050502
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:18407448
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:19255787
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:20963497
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21130809
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21246223
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21545631
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21601579
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: 2-acetyloxy-N,N,N-trimethylethanaminium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: ACETYLCHOLINE
database_cross_reference: PDBeChem

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: Acetylcholine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: acetylcholine
database_cross_reference: UniProt

Axiom
annotated source: acetylcholine
annotated property: hasRelatedSynonym
annotated target: ACh
database_cross_reference: ChemIDplus

Axiom
annotated source: acetylcholine
annotated property: hasRelatedSynonym
annotated target: Azetylcholin
database_cross_reference: ChEBI

Axiom
annotated source: acetylcholine
annotated property: hasRelatedSynonym
annotated target: O-Acetylcholine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetylcholine
annotated property: hasRelatedSynonym
annotated target: choline acetate
database_cross_reference: ChemIDplus

acetic acid
type: Class
subclass of: monocarboxylic acid
subclass of: Restriction
  on property: has role
  some values from: protic solvent
subclass of: Restriction
  on property: has role
  some values from: food acidity regulator
subclass of: Restriction
  on property: has role
  some values from: antimicrobial food preservative
subclass of: Restriction
  on property: has role
  some values from: Daphnia magna metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: acetate
definition: A simple monocarboxylic acid containing two carbons.
has alternative id: CHEBI:22169
has alternative id: CHEBI:2387
has alternative id: CHEBI:40486
database_cross_reference: CAS:64-19-7
database_cross_reference: Drug_Central:4211
database_cross_reference: Gmelin:1380
database_cross_reference: HMDB:HMDB0000042
database_cross_reference: KEGG:C00033
database_cross_reference: KEGG:D00010
database_cross_reference: KNApSAcK:C00001176
database_cross_reference: LIPID_MAPS_instance:LMFA01010002
database_cross_reference: MetaCyc:ACET
database_cross_reference: PDBeChem:ACT
database_cross_reference: PDBeChem:ACY
database_cross_reference: PMID:12005138
database_cross_reference: PMID:15107950
database_cross_reference: PMID:16630552
database_cross_reference: PMID:16774200
database_cross_reference: PMID:17190852
database_cross_reference: PMID:19416101
database_cross_reference: PMID:19469536
database_cross_reference: PMID:22153255
database_cross_reference: PMID:22173419
database_cross_reference: PPDB:1333
database_cross_reference: Reaxys:506007
database_cross_reference: Wikipedia:Acetic_acid
has_exact_synonym: ACETIC ACID
has_exact_synonym: Acetic acid
has_exact_synonym: acetic acid
has OBO namespace: chebi_ontology
has related synonym: AcOH
has related synonym: CH3-COOH
has related synonym: CH3CO2H
has related synonym: E 260
has related synonym: E-260
has related synonym: E260
has related synonym: Essigsaeure
has related synonym: Ethanoic acid
has related synonym: Ethylic acid
has related synonym: HOAc
has related synonym: INS No. 260
has related synonym: MeCO2H
has related synonym: MeCOOH
has related synonym: Methanecarboxylic acid
has related synonym: acide acetique
has related synonym: ethoic acid
id: CHEBI:15366
in subset: 3 STAR

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: CAS:64-19-7
source: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: CAS:64-19-7
source: KEGG COMPOUND

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: CAS:64-19-7
source: NIST Chemistry WebBook

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: Drug_Central:4211
source: DrugCentral

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: Gmelin:1380
source: Gmelin

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: LIPID_MAPS_instance:LMFA01010002
source: LIPID MAPS

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:12005138
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:15107950
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:16630552
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:16774200
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:17190852
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:19416101
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:19469536
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:22153255
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:22173419
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: Reaxys:506007
source: Reaxys

Axiom
annotated source: acetic acid
annotated property: has_exact_synonym
annotated target: ACETIC ACID
database_cross_reference: PDBeChem

Axiom
annotated source: acetic acid
annotated property: has_exact_synonym
annotated target: Acetic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetic acid
annotated property: has_exact_synonym
annotated target: acetic acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: AcOH
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: CH3-COOH
database_cross_reference: IUPAC

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: CH3CO2H
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: E 260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: E-260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: E260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: Essigsaeure
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: Ethanoic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: Ethylic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: HOAc
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: INS No. 260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: MeCO2H
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: MeCOOH
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: Methanecarboxylic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: acide acetique
database_cross_reference: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: hasRelatedSynonym
annotated target: ethoic acid
database_cross_reference: ChEBI

dioxygen
type: Class
subclass of: independent continuant
subclass of: gas molecular entity
subclass of: elemental molecule
subclass of: diatomic oxygen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: reagent
subclass of: Restriction
  on property: has role
  some values from: anti-inflammatory drug
subclass of: Restriction
  on property: has role
  some values from: oxidising agent
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: has role
  some values from: food packaging gas
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydridodioxygen(1+)
has alternative id: CHEBI:10745
has alternative id: CHEBI:13416
has alternative id: CHEBI:23833
has alternative id: CHEBI:25366
has alternative id: CHEBI:30491
has alternative id: CHEBI:44742
has alternative id: CHEBI:7860
database_cross_reference: CAS:7782-44-7
database_cross_reference: Gmelin:485
database_cross_reference: HMDB:HMDB0001377
database_cross_reference: KEGG:C00007
database_cross_reference: KEGG:D00003
database_cross_reference: MetaCyc:OXYGEN-MOLECULE
database_cross_reference: MolBase:750
database_cross_reference: PDBeChem:OXY
database_cross_reference: PMID:10906528
database_cross_reference: PMID:16977326
database_cross_reference: PMID:18210929
database_cross_reference: PMID:18638417
database_cross_reference: PMID:19840863
database_cross_reference: PMID:7710549
database_cross_reference: PMID:9463773
database_cross_reference: Wikipedia:Oxygen
has_exact_synonym: dioxygen
has OBO namespace: chebi_ontology
has related synonym: Disauerstoff
has related synonym: E 948
has related synonym: E-948
has related synonym: E948
has related synonym: O2
has related synonym: OXYGEN MOLECULE
has related synonym: Oxygen
has related synonym: [OO]
has related synonym: dioxygene
has related synonym: molecular oxygen
id: CHEBI:15379
in subset: 3 STAR

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: CAS:7782-44-7
source: ChemIDplus

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: CAS:7782-44-7
source: KEGG COMPOUND

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: CAS:7782-44-7
source: NIST Chemistry WebBook

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: Gmelin:485
source: Gmelin

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:10906528
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:16977326
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:18210929
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:18638417
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:19840863
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:7710549
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:9463773
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: has_exact_synonym
annotated target: dioxygen
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: Disauerstoff
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: E 948
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: E-948
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: E948
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: O2
database_cross_reference: IUPAC

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: O2
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: O2
database_cross_reference: UniProt

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: OXYGEN MOLECULE
database_cross_reference: PDBeChem

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: Oxygen
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: [OO]
database_cross_reference: MolBase

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: dioxygene
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: hasRelatedSynonym
annotated target: molecular oxygen
database_cross_reference: ChEBI

aldose
type: Class
subclass of: monosaccharide
definition: Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.
has alternative id: CHEBI:13755
has alternative id: CHEBI:22305
has alternative id: CHEBI:2561
database_cross_reference: KEGG:C01370
database_cross_reference: Wikipedia:Aldose
has_exact_synonym: Aldose
has OBO namespace: chebi_ontology
has related synonym: aldoses
has related synonym: an aldose
id: CHEBI:15693
in subset: 3 STAR

Axiom
annotated source: aldose
annotated property: has_exact_synonym
annotated target: Aldose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: aldose
annotated property: hasRelatedSynonym
annotated target: aldoses
database_cross_reference: ChEBI

Axiom
annotated source: aldose
annotated property: hasRelatedSynonym
annotated target: an aldose
database_cross_reference: UniProt

polypeptide
type: Class
subclass of: peptide
subclass of: macromolecule
definition: A peptide containing ten or more amino acid residues.
has alternative id: CHEBI:14860
has alternative id: CHEBI:8314
database_cross_reference: KEGG:C00403
has_exact_synonym: Polypeptide
has_exact_synonym: polypeptides
has OBO namespace: chebi_ontology
has related synonym: Polypeptid
has related synonym: polipeptido
id: CHEBI:15841
in subset: 3 STAR

Axiom
annotated source: polypeptide
annotated property: has_exact_synonym
annotated target: Polypeptide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polypeptide
annotated property: has_exact_synonym
annotated target: polypeptides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: polypeptide
annotated property: hasRelatedSynonym
annotated target: Polypeptid
database_cross_reference: ChEBI

Axiom
annotated source: polypeptide
annotated property: hasRelatedSynonym
annotated target: polipeptido
database_cross_reference: ChEBI

polynucleotide
type: Class
subclass of: information biomacromolecule
subclass of: nucleobase-containing molecular entity
subclass of: Restriction
  on property: has part
  some values from: nucleotide residue
definition: A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues.
has alternative id: CHEBI:13672
has alternative id: CHEBI:14859
has alternative id: CHEBI:8312
database_cross_reference: KEGG:C00419
has_exact_synonym: Polynucleotide
has OBO namespace: chebi_ontology
has related synonym: polynucleotides
id: CHEBI:15986
in subset: 3 STAR

Axiom
annotated source: polynucleotide
annotated property: has_exact_synonym
annotated target: Polynucleotide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polynucleotide
annotated property: hasRelatedSynonym
annotated target: polynucleotides
database_cross_reference: ChEBI

ammonia
type: Class
subclass of: independent continuant
subclass of: gas molecular entity
subclass of: azane
subclass of: mononuclear parent hydride
subclass of: Restriction
  on property: has role
  some values from: NMR chemical shift reference compound
subclass of: Restriction
  on property: has role
  some values from: neurotoxin
subclass of: Restriction
  on property: has role
  some values from: nucleophilic reagent
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
definition: An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
has alternative id: CHEBI:13405
has alternative id: CHEBI:13406
has alternative id: CHEBI:13407
has alternative id: CHEBI:13771
has alternative id: CHEBI:22533
has alternative id: CHEBI:44269
has alternative id: CHEBI:44284
has alternative id: CHEBI:44404
has alternative id: CHEBI:7434
database_cross_reference: CAS:7664-41-7
database_cross_reference: Drug_Central:4625
database_cross_reference: Gmelin:79
database_cross_reference: HMDB:HMDB0000051
database_cross_reference: KEGG:C00014
database_cross_reference: KEGG:D02916
database_cross_reference: KNApSAcK:C00007267
database_cross_reference: MetaCyc:AMMONIA
database_cross_reference: MolBase:930
database_cross_reference: PDBeChem:NH3
database_cross_reference: PMID:110589
database_cross_reference: PMID:11139349
database_cross_reference: PMID:11540049
database_cross_reference: PMID:11746427
database_cross_reference: PMID:11783653
database_cross_reference: PMID:13753780
database_cross_reference: PMID:14663195
database_cross_reference: PMID:15092448
database_cross_reference: PMID:15094021
database_cross_reference: PMID:15554424
database_cross_reference: PMID:15969015
database_cross_reference: PMID:16008360
database_cross_reference: PMID:16050680
database_cross_reference: PMID:16348008
database_cross_reference: PMID:16349403
database_cross_reference: PMID:16614889
database_cross_reference: PMID:16664306
database_cross_reference: PMID:16842901
database_cross_reference: PMID:17025297
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17569513
database_cross_reference: PMID:17737668
database_cross_reference: PMID:18670398
database_cross_reference: PMID:22002069
database_cross_reference: PMID:22081570
database_cross_reference: PMID:22088435
database_cross_reference: PMID:22100291
database_cross_reference: PMID:22130175
database_cross_reference: PMID:22150211
database_cross_reference: PMID:22240068
database_cross_reference: PMID:22290316
database_cross_reference: PMID:22342082
database_cross_reference: PMID:22385337
database_cross_reference: PMID:22443779
database_cross_reference: PMID:22560242
database_cross_reference: Reaxys:3587154
database_cross_reference: Wikipedia:Ammonia
has_exact_synonym: AMMONIA
has_exact_synonym: Ammonia
has_exact_synonym: ammonia
has_exact_synonym: azane
has OBO namespace: chebi_ontology
has related synonym: Ammoniak
has related synonym: NH3
has related synonym: R-717
has related synonym: [NH3]
has related synonym: ammoniac
has related synonym: amoniaco
has related synonym: spirit of hartshorn
id: CHEBI:16134
in subset: 3 STAR

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: CAS:7664-41-7
source: ChemIDplus

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: CAS:7664-41-7
source: KEGG COMPOUND

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: CAS:7664-41-7
source: NIST Chemistry WebBook

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: Drug_Central:4625
source: DrugCentral

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: Gmelin:79
source: Gmelin

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:110589
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11139349
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11540049
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11746427
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11783653
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:13753780
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:14663195
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15092448
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15094021
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15554424
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15969015
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16008360
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16050680
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16348008
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16349403
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16614889
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16664306
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16842901
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17025297
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17439666
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17569513
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17737668
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:18670398
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22002069
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22081570
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22088435
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22100291
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22130175
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22150211
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22240068
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22290316
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22342082
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22385337
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22443779
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22560242
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: Reaxys:3587154
source: Reaxys

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: AMMONIA
database_cross_reference: PDBeChem

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: Ammonia
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: ammonia
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: azane
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: Ammoniak
database_cross_reference: ChemIDplus

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: NH3
database_cross_reference: IUPAC

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: NH3
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: R-717
database_cross_reference: ChEBI

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: [NH3]
database_cross_reference: MolBase

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: ammoniac
database_cross_reference: ChEBI

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: amoniaco
database_cross_reference: ChEBI

Axiom
annotated source: ammonia
annotated property: hasRelatedSynonym
annotated target: spirit of hartshorn
database_cross_reference: ChemIDplus

sulfate
type: Class
subclass of: independent continuant
subclass of: sulfur oxoanion
subclass of: sulfur oxide
subclass of: divalent inorganic anion
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogensulfate
definition: A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid.
has alternative id: CHEBI:15135
has alternative id: CHEBI:45687
has alternative id: CHEBI:9335
database_cross_reference: CAS:14808-79-8
database_cross_reference: Gmelin:2120
database_cross_reference: HMDB:HMDB0001448
database_cross_reference: KEGG:C00059
database_cross_reference: KEGG:D05963
database_cross_reference: MetaCyc:SULFATE
database_cross_reference: PDBeChem:SO4
database_cross_reference: PMID:11200094
database_cross_reference: PMID:11452993
database_cross_reference: PMID:11581495
database_cross_reference: PMID:11798107
database_cross_reference: PMID:12166931
database_cross_reference: PMID:12668033
database_cross_reference: PMID:14597181
database_cross_reference: PMID:15093386
database_cross_reference: PMID:15984785
database_cross_reference: PMID:16186560
database_cross_reference: PMID:16345535
database_cross_reference: PMID:16347366
database_cross_reference: PMID:16348007
database_cross_reference: PMID:16483812
database_cross_reference: PMID:16534979
database_cross_reference: PMID:16656509
database_cross_reference: PMID:16742508
database_cross_reference: PMID:16742518
database_cross_reference: PMID:17120760
database_cross_reference: PMID:17420092
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17709180
database_cross_reference: PMID:18398178
database_cross_reference: PMID:18815700
database_cross_reference: PMID:18846414
database_cross_reference: PMID:19047345
database_cross_reference: PMID:19244483
database_cross_reference: PMID:19544990
database_cross_reference: PMID:19628332
database_cross_reference: PMID:19812358
database_cross_reference: PMID:30398859
database_cross_reference: Reaxys:3648446
database_cross_reference: Wikipedia:Sulfate
has_exact_synonym: Sulfate
has_exact_synonym: sulfate
has_exact_synonym: tetraoxidosulfate(2-)
has_exact_synonym: tetraoxosulfate(2-)
has_exact_synonym: tetraoxosulfate(VI)
has OBO namespace: chebi_ontology
has related synonym: SO4(2-)
has related synonym: SULFATE ION
has related synonym: Sulfate anion(2-)
has related synonym: Sulfate dianion
has related synonym: Sulfate(2-)
has related synonym: Sulfuric acid ion(2-)
has related synonym: [SO4](2-)
has related synonym: sulphate
has related synonym: sulphate ion
id: CHEBI:16189
in subset: 3 STAR

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: CAS:14808-79-8
source: ChemIDplus

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: CAS:14808-79-8
source: NIST Chemistry WebBook

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: Gmelin:2120
source: Gmelin

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11200094
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11452993
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11581495
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11798107
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:12166931
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:12668033
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:14597181
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:15093386
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:15984785
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16186560
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16345535
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16347366
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16348007
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16483812
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16534979
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16656509
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16742508
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16742518
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17120760
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17420092
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17439666
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17709180
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:18398178
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:18815700
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:18846414
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19047345
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19244483
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19544990
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19628332
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19812358
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:30398859
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: Reaxys:3648446
source: Reaxys

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: Sulfate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: sulfate
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: sulfate
database_cross_reference: UniProt

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: tetraoxidosulfate(2-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: tetraoxosulfate(2-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: tetraoxosulfate(VI)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: SO4(2-)
database_cross_reference: IUPAC

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: SULFATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: Sulfate anion(2-)
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: Sulfate dianion
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: Sulfate(2-)
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: Sulfuric acid ion(2-)
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: [SO4](2-)
database_cross_reference: IUPAC

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: sulphate
database_cross_reference: ChEBI

Axiom
annotated source: sulfate
annotated property: hasRelatedSynonym
annotated target: sulphate ion
database_cross_reference: ChEBI

hyaluronic acid
type: Class
subclass of: independent continuant
subclass of: mucopolysaccharide
subclass of: exopolysaccharide
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hyaluronate
definition: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells.
has alternative id: CHEBI:14412
has alternative id: CHEBI:24622
has alternative id: CHEBI:24623
has alternative id: CHEBI:5772
database_cross_reference: Beilstein:8538277
database_cross_reference: CAS:9004-61-9
database_cross_reference: HMDB:HMDB0010366
database_cross_reference: KEGG:C00518
database_cross_reference: KEGG:D08043
database_cross_reference: KEGG:G10505
database_cross_reference: PMID:11122186
database_cross_reference: PMID:18056362
database_cross_reference: PMID:18290544
database_cross_reference: Reaxys:8187837
database_cross_reference: Wikipedia:Hyaluronan
has_exact_synonym: Hyaluronic acid
has OBO namespace: chebi_ontology
has related synonym: Hyaluronsaeure
has related synonym: [beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n
has related synonym: [beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n
has related synonym: acide hyaluronique
has related synonym: acido hialuronico
has related synonym: hyaluronan
id: CHEBI:16336
in subset: 3 STAR

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: Beilstein:8538277
source: Beilstein

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: CAS:9004-61-9
source: ChemIDplus

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: CAS:9004-61-9
source: KEGG COMPOUND

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: PMID:11122186
source: Europe PMC

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: PMID:18056362
source: Europe PMC

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: PMID:18290544
source: Europe PMC

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: Reaxys:8187837
source: Reaxys

Axiom
annotated source: hyaluronic acid
annotated property: has_exact_synonym
annotated target: Hyaluronic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hyaluronic acid
annotated property: hasRelatedSynonym
annotated target: Hyaluronsaeure
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: hasRelatedSynonym
annotated target: [beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: hasRelatedSynonym
annotated target: [beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hyaluronic acid
annotated property: hasRelatedSynonym
annotated target: acide hyaluronique
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: hasRelatedSynonym
annotated target: acido hialuronico
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: hasRelatedSynonym
annotated target: hyaluronan
database_cross_reference: ChEBI

protein polypeptide chain
type: Class
subclass of: polypeptide
subclass of: Restriction
  on property: has part
  some values from: proteinogenic amino-acid residue
definition: A naturally occurring polypeptide synthesized at the ribosome.
has alternative id: CHEBI:8526
database_cross_reference: KEGG:C00017
has OBO namespace: chebi_ontology
has related synonym: Protein
has related synonym: a protein
has related synonym: polypeptide chain
has related synonym: protein polypeptide chains
id: CHEBI:16541
in subset: 3 STAR

Axiom
annotated source: protein polypeptide chain
annotated property: hasRelatedSynonym
annotated target: Protein
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: protein polypeptide chain
annotated property: hasRelatedSynonym
annotated target: a protein
database_cross_reference: UniProt

Axiom
annotated source: protein polypeptide chain
annotated property: hasRelatedSynonym
annotated target: polypeptide chain
database_cross_reference: ChEBI

Axiom
annotated source: protein polypeptide chain
annotated property: hasRelatedSynonym
annotated target: protein polypeptide chains
database_cross_reference: ChEBI

carbohydrate
type: Class
subclass of: carbohydrates and carbohydrate derivatives
definition: Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.
has alternative id: CHEBI:15131
has alternative id: CHEBI:23008
has alternative id: CHEBI:9318
database_cross_reference: Wikipedia:Carbohydrate
has_exact_synonym: carbohydrate
has_exact_synonym: carbohydrates
has OBO namespace: chebi_ontology
has related synonym: Kohlenhydrat
has related synonym: Kohlenhydrate
has related synonym: a carbohydrate
has related synonym: carbohidrato
has related synonym: carbohidratos
has related synonym: glucide
has related synonym: glucides
has related synonym: glucido
has related synonym: glucidos
has related synonym: hydrates de carbone
has related synonym: saccharide
has related synonym: saccharides
has related synonym: saccharidum
id: CHEBI:16646
in subset: 3 STAR

Axiom
annotated source: carbohydrate
annotated property: has_exact_synonym
annotated target: carbohydrate
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbohydrate
annotated property: has_exact_synonym
annotated target: carbohydrates
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: Kohlenhydrat
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: Kohlenhydrate
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: a carbohydrate
database_cross_reference: UniProt

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: carbohidrato
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: carbohidratos
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: glucide
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: glucides
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: glucido
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: glucidos
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: hydrates de carbone
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: saccharide
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: saccharides
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: hasRelatedSynonym
annotated target: saccharidum
database_cross_reference: ChEBI

peptide
type: Class
subclass of: carboxamide
subclass of: organic amino compound
subclass of: Restriction
  on property: has part
  some values from: amino-acid residue
subclass of: Restriction
  on property: is tautomer of
  some values from: peptide zwitterion
definition: Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
has alternative id: CHEBI:14753
has alternative id: CHEBI:25906
has alternative id: CHEBI:7990
database_cross_reference: KEGG:C00012
has_exact_synonym: Peptide
has_exact_synonym: peptides
has OBO namespace: chebi_ontology
has related synonym: Peptid
has related synonym: peptido
has related synonym: peptidos
id: CHEBI:16670
in subset: 3 STAR

Axiom
annotated source: peptide
annotated property: has_exact_synonym
annotated target: Peptide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: peptide
annotated property: has_exact_synonym
annotated target: peptides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: peptide
annotated property: hasRelatedSynonym
annotated target: Peptid
database_cross_reference: ChEBI

Axiom
annotated source: peptide
annotated property: hasRelatedSynonym
annotated target: peptido
database_cross_reference: ChEBI

Axiom
annotated source: peptide
annotated property: hasRelatedSynonym
annotated target: peptidos
database_cross_reference: ChEBI

noradrenaline(1+)
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: noradrenaline
has OBO namespace: chebi_ontology
has related synonym: noradrenaline
id: CHEBI:166902
in subset: 2 STAR

Axiom
annotated source: noradrenaline(1+)
annotated property: hasRelatedSynonym
annotated target: noradrenaline
database_cross_reference: UniProt

glycan
type: Class
subclass of: carbohydrates and carbohydrate derivatives
definition: Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001.
has OBO namespace: chebi_ontology
has related synonym: glycans
id: CHEBI:167559
in subset: 3 STAR

Axiom
annotated source: glycan
annotated property: hasRelatedSynonym
annotated target: glycans
database_cross_reference: ChEBI

tryptamine
type: Class
subclass of: tryptamines
subclass of: aminoalkylindole
subclass of: indole alkaloid
subclass of: aralkylamino compound
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: tryptaminium
definition: An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.
has alternative id: CHEBI:15274
has alternative id: CHEBI:27161
has alternative id: CHEBI:46157
has alternative id: CHEBI:9767
database_cross_reference: CAS:61-54-1
database_cross_reference: DrugBank:DB08653
database_cross_reference: Gmelin:603448
database_cross_reference: HMDB:HMDB0000303
database_cross_reference: KEGG:C00398
database_cross_reference: KNApSAcK:C00001434
database_cross_reference: MetaCyc:TRYPTAMINE
database_cross_reference: PDBeChem:TSS
database_cross_reference: PMID:16126914
database_cross_reference: PMID:22770225
database_cross_reference: PMID:24345948
database_cross_reference: PMID:24558969
database_cross_reference: Reaxys:125513
database_cross_reference: Wikipedia:Tryptamine
has_exact_synonym: 2-(1H-indol-3-yl)ethanamine
has_exact_synonym: Tryptamine
has OBO namespace: chebi_ontology
has related synonym: 1H-indole-3-ethanamine
has related synonym: 2-(1H-INDOL-3-YL)ETHANAMINE
has related synonym: 2-(3-indolyl)ethylamine
has related synonym: 3-(2-Aminoethyl)indole
id: CHEBI:16765
in subset: 3 STAR

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: CAS:61-54-1
source: ChemIDplus

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: CAS:61-54-1
source: KEGG COMPOUND

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: CAS:61-54-1
source: NIST Chemistry WebBook

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: Gmelin:603448
source: Gmelin

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:16126914
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:22770225
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:24345948
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:24558969
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: Reaxys:125513
source: Reaxys

Axiom
annotated source: tryptamine
annotated property: has_exact_synonym
annotated target: 2-(1H-indol-3-yl)ethanamine
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: tryptamine
annotated property: has_exact_synonym
annotated target: Tryptamine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: tryptamine
annotated property: hasRelatedSynonym
annotated target: 1H-indole-3-ethanamine
database_cross_reference: NIST_Chemistry_WebBook

Axiom
annotated source: tryptamine
annotated property: hasRelatedSynonym
annotated target: 2-(1H-INDOL-3-YL)ETHANAMINE
database_cross_reference: PDBeChem

Axiom
annotated source: tryptamine
annotated property: hasRelatedSynonym
annotated target: 2-(3-indolyl)ethylamine
database_cross_reference: ChemIDplus

Axiom
annotated source: tryptamine
annotated property: hasRelatedSynonym
annotated target: 3-(2-Aminoethyl)indole
database_cross_reference: KEGG_COMPOUND

bilirubin IXalpha
type: Class
subclass of: dicarboxylic acid
subclass of: biladienes
subclass of: Restriction
  on property: has part
  some values from: 24G7 epitope
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: bilirubin(2-)
definition: A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.
has alternative id: CHEBI:13898
has alternative id: CHEBI:22870
has alternative id: CHEBI:3099
database_cross_reference: CAS:635-65-4
database_cross_reference: Gmelin:411033
database_cross_reference: HMDB:HMDB0000054
database_cross_reference: KEGG:C00486
database_cross_reference: KNApSAcK:C00029828
database_cross_reference: MetaCyc:BILIRUBIN
database_cross_reference: PDBeChem:BLR
database_cross_reference: PMID:12799017
database_cross_reference: PMID:18442622
database_cross_reference: PMID:23763371
database_cross_reference: PMID:23768684
database_cross_reference: PMID:30224965
database_cross_reference: PMID:8605219
database_cross_reference: PMID:9587403
database_cross_reference: Reaxys:74376
database_cross_reference: Wikipedia:Bilirubin
has_exact_synonym: 3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
has_exact_synonym: bilirubin
has OBO namespace: chebi_ontology
has related synonym: 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid
has related synonym: 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
has related synonym: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
has related synonym: 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione
has related synonym: Bilirubin
has related synonym: bilirubin(Z,Z)
has related synonym: bilirubin-IXalpha
id: CHEBI:16990
in subset: 3 STAR

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: CAS:635-65-4
source: ChemIDplus

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: CAS:635-65-4
source: KEGG COMPOUND

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: Gmelin:411033
source: Gmelin

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:12799017
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:18442622
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:23763371
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:23768684
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:30224965
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:8605219
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:9587403
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: Reaxys:74376
source: Reaxys

Axiom
annotated source: bilirubin IXalpha
annotated property: has_exact_synonym
annotated target: 3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: bilirubin IXalpha
annotated property: has_exact_synonym
annotated target: bilirubin
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: bilirubin IXalpha
annotated property: hasRelatedSynonym
annotated target: 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: bilirubin IXalpha
annotated property: hasRelatedSynonym
annotated target: 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: bilirubin IXalpha
annotated property: hasRelatedSynonym
annotated target: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
database_cross_reference: IUPAC

Axiom
annotated source: bilirubin IXalpha
annotated property: hasRelatedSynonym
annotated target: 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione
database_cross_reference: JCBN

Axiom
annotated source: bilirubin IXalpha
annotated property: hasRelatedSynonym
annotated target: Bilirubin
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bilirubin IXalpha
annotated property: hasRelatedSynonym
annotated target: bilirubin(Z,Z)
database_cross_reference: ChEBI

Axiom
annotated source: bilirubin IXalpha
annotated property: hasRelatedSynonym
annotated target: bilirubin-IXalpha
database_cross_reference: ChEBI

ketone
type: Class
subclass of: carbonyl compound
definition: A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).
has alternative id: CHEBI:13427
has alternative id: CHEBI:13646
has alternative id: CHEBI:24974
has alternative id: CHEBI:6127
has alternative id: CHEBI:8742
database_cross_reference: KEGG:C01450
database_cross_reference: Wikipedia:Ketone
has_exact_synonym: Ketone
has_exact_synonym: ketones
has OBO namespace: chebi_ontology
has related synonym: Keton
has related synonym: R-CO-R'
has related synonym: a ketone
has related synonym: cetone
has related synonym: ketones
id: CHEBI:17087
in subset: 3 STAR

Axiom
annotated source: ketone
annotated property: has_exact_synonym
annotated target: Ketone
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ketone
annotated property: has_exact_synonym
annotated target: ketones
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: ketone
annotated property: hasRelatedSynonym
annotated target: Keton
database_cross_reference: ChEBI

Axiom
annotated source: ketone
annotated property: hasRelatedSynonym
annotated target: R-CO-R'
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ketone
annotated property: hasRelatedSynonym
annotated target: a ketone
database_cross_reference: UniProt

Axiom
annotated source: ketone
annotated property: hasRelatedSynonym
annotated target: cetone
database_cross_reference: ChEBI

Axiom
annotated source: ketone
annotated property: hasRelatedSynonym
annotated target: ketones
database_cross_reference: ChEBI

glycoprotein
type: Class
subclass of: conjugated protein
subclass of: carbohydrate derivative
definition: A compound in which a carbohydrate component is covalently bound to a protein component.
has alternative id: CHEBI:14349
has alternative id: CHEBI:5481
has alternative id: CHEBI:5493
database_cross_reference: KEGG:C00326
has_exact_synonym: Glycoprotein
has_exact_synonym: glycoproteins
has OBO namespace: chebi_ontology
has related synonym: Glykoprotein
has related synonym: Glykoproteine
has related synonym: a glycoprotein
has related synonym: glicoproteina
has related synonym: glicoproteinas
has related synonym: glycoproteine
has related synonym: glycoproteines
id: CHEBI:17089
in subset: 3 STAR

Axiom
annotated source: glycoprotein
annotated property: has_exact_synonym
annotated target: Glycoprotein
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glycoprotein
annotated property: has_exact_synonym
annotated target: glycoproteins
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: glycoprotein
annotated property: hasRelatedSynonym
annotated target: Glykoprotein
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: hasRelatedSynonym
annotated target: Glykoproteine
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: hasRelatedSynonym
annotated target: a glycoprotein
database_cross_reference: UniProt

Axiom
annotated source: glycoprotein
annotated property: hasRelatedSynonym
annotated target: glicoproteina
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: hasRelatedSynonym
annotated target: glicoproteinas
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: hasRelatedSynonym
annotated target: glycoproteine
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: hasRelatedSynonym
annotated target: glycoproteines
database_cross_reference: ChEBI

glucose
type: Class
subclass of: independent continuant
subclass of: aldohexose
subclass of: Restriction
  on property: has role
  some values from: fundamental metabolite
definition: An aldohexose used as a source of energy and metabolic intermediate.
has alternative id: CHEBI:14313
has alternative id: CHEBI:24277
has alternative id: CHEBI:33929
has alternative id: CHEBI:5418
database_cross_reference: CAS:50-99-7
database_cross_reference: KEGG:C00293
database_cross_reference: Wikipedia:Glucose
has_exact_synonym: Glucose
has_exact_synonym: gluco-hexose
has_exact_synonym: glucose
has OBO namespace: chebi_ontology
has related synonym: DL-glucose
has related synonym: Glc
has related synonym: Glukose
id: CHEBI:17234
in subset: 3 STAR

Axiom
annotated source: glucose
annotated property: database_cross_reference
annotated target: CAS:50-99-7
source: KEGG COMPOUND

Axiom
annotated source: glucose
annotated property: has_exact_synonym
annotated target: Glucose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glucose
annotated property: has_exact_synonym
annotated target: gluco-hexose
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: glucose
annotated property: has_exact_synonym
annotated target: glucose
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: glucose
annotated property: hasRelatedSynonym
annotated target: DL-glucose
database_cross_reference: ChEBI

Axiom
annotated source: glucose
annotated property: hasRelatedSynonym
annotated target: Glc
database_cross_reference: JCBN

Axiom
annotated source: glucose
annotated property: hasRelatedSynonym
annotated target: Glukose
database_cross_reference: ChEBI

hydrogencarbonate
type: Class
subclass of: independent continuant
subclass of: carbon oxoanion
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbonate
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbonic acid
definition: The carbon oxoanion resulting from the removal of a proton from carbonic acid.
has alternative id: CHEBI:13363
has alternative id: CHEBI:22863
has alternative id: CHEBI:40961
has alternative id: CHEBI:5589
database_cross_reference: Beilstein:3903504
database_cross_reference: CAS:71-52-3
database_cross_reference: Gmelin:49249
database_cross_reference: HMDB:HMDB0000595
database_cross_reference: KEGG:C00288
database_cross_reference: MetaCyc:HCO3
database_cross_reference: PDBeChem:BCT
database_cross_reference: PMID:17215880
database_cross_reference: PMID:17505962
database_cross_reference: PMID:18439416
database_cross_reference: PMID:28732801
database_cross_reference: PMID:29150416
database_cross_reference: PMID:29460248
database_cross_reference: PMID:29466234
database_cross_reference: PMID:4208463
database_cross_reference: Wikipedia:Bicarbonate
has_exact_synonym: Hydrogencarbonate
has_exact_synonym: hydrogen(trioxidocarbonate)(1-)
has_exact_synonym: hydrogencarbonate
has_exact_synonym: hydrogencarbonate(1-)
has_exact_synonym: hydrogentrioxocarbonate(1-)
has_exact_synonym: hydrogentrioxocarbonate(IV)
has_exact_synonym: hydroxidodioxidocarbonate(1-)
has OBO namespace: chebi_ontology
has related synonym: Acid carbonate
has related synonym: BICARBONATE ION
has related synonym: Bicarbonate
has related synonym: HCO3(-)
has related synonym: HCO3-
has related synonym: [CO2(OH)](-)
has related synonym: hydrogen carbonate
id: CHEBI:17544
in subset: 3 STAR

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: Beilstein:3903504
source: Beilstein

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: CAS:71-52-3
source: ChemIDplus

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: Gmelin:49249
source: Gmelin

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:17215880
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:17505962
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:18439416
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:28732801
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:29150416
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:29460248
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:29466234
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:4208463
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: Hydrogencarbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogen(trioxidocarbonate)(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogencarbonate
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogencarbonate
database_cross_reference: UniProt

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogencarbonate(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogentrioxocarbonate(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogentrioxocarbonate(IV)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydroxidodioxidocarbonate(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: hasRelatedSynonym
annotated target: Acid carbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: hasRelatedSynonym
annotated target: BICARBONATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: hydrogencarbonate
annotated property: hasRelatedSynonym
annotated target: Bicarbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: hasRelatedSynonym
annotated target: HCO3(-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogencarbonate
annotated property: hasRelatedSynonym
annotated target: HCO3-
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: hasRelatedSynonym
annotated target: [CO2(OH)](-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogencarbonate
annotated property: hasRelatedSynonym
annotated target: hydrogen carbonate
database_cross_reference: PDBeChem

D-aldohexose
type: Class
subclass of: aldohexose
subclass of: D-hexose
definition: Any D-aldose having a chain of six carbon atoms in the molecule.
has alternative id: CHEBI:12990
has alternative id: CHEBI:21038
has OBO namespace: chebi_ontology
has related synonym: D-aldohexoses
id: CHEBI:17608
in subset: 3 STAR

Axiom
annotated source: D-aldohexose
annotated property: hasRelatedSynonym
annotated target: D-aldohexoses
database_cross_reference: ChEBI

D-glucose
type: Class
subclass of: glucose
subclass of: D-aldohexose
definition: A glucose with D-configuration.
has alternative id: CHEBI:12965
has alternative id: CHEBI:20999
database_cross_reference: CAS:50-99-7
has_exact_synonym: D-gluco-hexose
has_exact_synonym: D-glucose
has OBO namespace: chebi_ontology
has related synonym: D(+)-glucose
has related synonym: D-(+)-glucose
has related synonym: Traubenzucker
has related synonym: dextrose
has related synonym: grape sugar
id: CHEBI:17634
in subset: 3 STAR

Axiom
annotated source: D-glucose
annotated property: database_cross_reference
annotated target: CAS:50-99-7
source: ChemIDplus

Axiom
annotated source: D-glucose
annotated property: database_cross_reference
annotated target: CAS:50-99-7
source: NIST Chemistry WebBook

Axiom
annotated source: D-glucose
annotated property: has_exact_synonym
annotated target: D-gluco-hexose
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: D-glucose
annotated property: has_exact_synonym
annotated target: D-glucose
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: D-glucose
annotated property: hasRelatedSynonym
annotated target: D(+)-glucose
database_cross_reference: ChemIDplus

Axiom
annotated source: D-glucose
annotated property: hasRelatedSynonym
annotated target: D-(+)-glucose
database_cross_reference: NIST_Chemistry_WebBook

Axiom
annotated source: D-glucose
annotated property: hasRelatedSynonym
annotated target: Traubenzucker
database_cross_reference: ChemIDplus

Axiom
annotated source: D-glucose
annotated property: hasRelatedSynonym
annotated target: dextrose
database_cross_reference: NIST_Chemistry_WebBook

Axiom
annotated source: D-glucose
annotated property: hasRelatedSynonym
annotated target: grape sugar
database_cross_reference: ChemIDplus

donor
type: Class
subclass of: chemical role
definition: A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
has alternative id: CHEBI:14202
has alternative id: CHEBI:4697
database_cross_reference: KEGG:C01351
has_exact_synonym: Donor
has OBO namespace: chebi_ontology
has related synonym: Donator
has related synonym: donneur
id: CHEBI:17891
in subset: 3 STAR

Axiom
annotated source: donor
annotated property: has_exact_synonym
annotated target: Donor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: donor
annotated property: hasRelatedSynonym
annotated target: Donator
database_cross_reference: ChEBI

Axiom
annotated source: donor
annotated property: hasRelatedSynonym
annotated target: donneur
database_cross_reference: ChEBI

lipid
type: Class
subclass of: organic molecular entity
definition: 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
has alternative id: CHEBI:14517
has alternative id: CHEBI:25054
has alternative id: CHEBI:6486
database_cross_reference: KEGG:C01356
has_exact_synonym: Lipid
has_exact_synonym: lipids
has OBO namespace: chebi_ontology
id: CHEBI:18059
in subset: 3 STAR

Axiom
annotated source: lipid
annotated property: has_exact_synonym
annotated target: Lipid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: lipid
annotated property: has_exact_synonym
annotated target: lipids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

glycosaminoglycan
type: Class
subclass of: aminoglycan
definition: Any polysaccharide containing a substantial proportion of aminomonosaccharide residues.
has alternative id: CHEBI:14361
has alternative id: CHEBI:24398
has alternative id: CHEBI:5495
database_cross_reference: KEGG:C02545
database_cross_reference: Wikipedia:Glycosaminoglycan
has_exact_synonym: Glycosaminoglycan
has_exact_synonym: glycosaminoglycan
has OBO namespace: chebi_ontology
has related synonym: Glykosaminoglykan
has related synonym: glicosaminoglicano
has related synonym: glycosaminoglycane
has related synonym: glycosaminoglycans
id: CHEBI:18085
in subset: 3 STAR

Axiom
annotated source: glycosaminoglycan
annotated property: has_exact_synonym
annotated target: Glycosaminoglycan
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glycosaminoglycan
annotated property: has_exact_synonym
annotated target: glycosaminoglycan
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: glycosaminoglycan
annotated property: hasRelatedSynonym
annotated target: Glykosaminoglykan
database_cross_reference: ChEBI

Axiom
annotated source: glycosaminoglycan
annotated property: hasRelatedSynonym
annotated target: glicosaminoglicano
database_cross_reference: IUPAC

Axiom
annotated source: glycosaminoglycan
annotated property: hasRelatedSynonym
annotated target: glycosaminoglycane
database_cross_reference: IUPAC

Axiom
annotated source: glycosaminoglycan
annotated property: hasRelatedSynonym
annotated target: glycosaminoglycans
database_cross_reference: ChEBI

hexose
type: Class
subclass of: monosaccharide
definition: Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose).
has alternative id: CHEBI:14399
has alternative id: CHEBI:24590
has alternative id: CHEBI:5709
database_cross_reference: GlyGen:G70994MS
database_cross_reference: GlyTouCan:G70994MS
database_cross_reference: KEGG:C00738
has_exact_synonym: Hexose
has OBO namespace: chebi_ontology
has related synonym: WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/
has related synonym: hexoses
id: CHEBI:18133
in subset: 3 STAR

Axiom
annotated source: hexose
annotated property: has_exact_synonym
annotated target: Hexose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hexose
annotated property: hasRelatedSynonym
annotated target: WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/
database_cross_reference: GlyTouCan

Axiom
annotated source: hexose
annotated property: hasRelatedSynonym
annotated target: hexoses
database_cross_reference: ChEBI

polysaccharide
type: Class
subclass of: carbohydrate
subclass of: glycan
subclass of: biomacromolecule
definition: A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.
has alternative id: CHEBI:14864
has alternative id: CHEBI:26205
has alternative id: CHEBI:8322
database_cross_reference: KEGG:C00420
has_exact_synonym: Polysaccharide
has_exact_synonym: polysaccharides
has OBO namespace: chebi_ontology
has related synonym: Glycan
has related synonym: Glycane
has related synonym: Glykan
has related synonym: Glykane
has related synonym: glycans
has related synonym: polisacarido
has related synonym: polisacaridos
id: CHEBI:18154
in subset: 3 STAR

Axiom
annotated source: polysaccharide
annotated property: has_exact_synonym
annotated target: Polysaccharide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polysaccharide
annotated property: has_exact_synonym
annotated target: polysaccharides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: polysaccharide
annotated property: hasRelatedSynonym
annotated target: Glycan
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polysaccharide
annotated property: hasRelatedSynonym
annotated target: Glycane
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: hasRelatedSynonym
annotated target: Glykan
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: hasRelatedSynonym
annotated target: Glykane
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: hasRelatedSynonym
annotated target: glycans
database_cross_reference: IUPAC

Axiom
annotated source: polysaccharide
annotated property: hasRelatedSynonym
annotated target: polisacarido
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: hasRelatedSynonym
annotated target: polisacaridos
database_cross_reference: IUPAC

nucleobase
type: Class
subclass of: organonitrogen heterocyclic compound
definition: That part of DNA or RNA that may be involved in pairing.
has alternative id: CHEBI:13873
has alternative id: CHEBI:25598
has alternative id: CHEBI:2995
database_cross_reference: KEGG:C00701
database_cross_reference: Wikipedia:Nucleobase
has OBO namespace: chebi_ontology
has related synonym: Base
has related synonym: nucleobases
id: CHEBI:18282
in subset: 3 STAR

Axiom
annotated source: nucleobase
annotated property: hasRelatedSynonym
annotated target: Base
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: nucleobase
annotated property: hasRelatedSynonym
annotated target: nucleobases
database_cross_reference: ChEBI

(R)-noradrenaline
type: Class
subclass of: noradrenaline
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: sympathomimetic agent
subclass of: Restriction
  on property: has role
  some values from: alpha-adrenergic agonist
subclass of: Restriction
  on property: has role
  some values from: vasoconstrictor agent
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: (R)-noradrenaline(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: (S)-noradrenaline
definition: The R-enantiomer of noradrenaline.
has alternative id: CHEBI:1
has alternative id: CHEBI:14668
has alternative id: CHEBI:25592
has alternative id: CHEBI:258884
has alternative id: CHEBI:43725
database_cross_reference: Beilstein:4231961
database_cross_reference: CAS:51-41-2
database_cross_reference: DrugBank:DB00368
database_cross_reference: Drug_Central:1960
database_cross_reference: HMDB:HMDB0000216
database_cross_reference: KEGG:C00547
database_cross_reference: KEGG:D00076
database_cross_reference: KNApSAcK:C00001424
database_cross_reference: PDBeChem:LNR
database_cross_reference: Reaxys:2804840
database_cross_reference: Wikipedia:Norepinephrine
has_exact_synonym: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
has OBO namespace: chebi_ontology
has related synonym: (-)-arterenol
has related synonym: (-)-noradrenaline
has related synonym: (-)-norepinephrine
has related synonym: (R)-(-)-norepinephrine
has related synonym: (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol
has related synonym: (R)-norepinephrine
has related synonym: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
has related synonym: Arterenol
has related synonym: L-NOREPINEPHRINE
has related synonym: L-Noradrenaline
has related synonym: Noradrenaline
has related synonym: Norepinephrine
has related synonym: norepinefrina
has related synonym: norepinephrine
has related synonym: norepinephrinum
id: CHEBI:18357
in subset: 3 STAR

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: Beilstein:4231961
source: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: CAS:51-41-2
source: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: CAS:51-41-2
source: KEGG COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: Drug_Central:1960
source: DrugCentral

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: Reaxys:2804840
source: Reaxys

Axiom
annotated source: (R)-noradrenaline
annotated property: has_exact_synonym
annotated target: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: (-)-arterenol
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: (-)-noradrenaline
database_cross_reference: IUPHAR

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: (-)-norepinephrine
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: (R)-(-)-norepinephrine
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: (R)-norepinephrine
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: Arterenol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: L-NOREPINEPHRINE
database_cross_reference: PDBeChem

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: L-Noradrenaline
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: Noradrenaline
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: Norepinephrine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: norepinefrina
database_cross_reference: ChEBI
has synonym type: INN

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: norepinephrine
database_cross_reference: ChemIDplus
has synonym type: INN

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: norepinephrine
database_cross_reference: WHO_MedNet
has synonym type: INN

Axiom
annotated source: (R)-noradrenaline
annotated property: hasRelatedSynonym
annotated target: norepinephrinum
database_cross_reference: ChEBI
has synonym type: INN

5beta-cholane
type: Class
subclass of: cholane
database_cross_reference: Beilstein:2048472
has_exact_synonym: 5beta-cholane
has OBO namespace: chebi_ontology
id: CHEBI:20664
in subset: 3 STAR

Axiom
annotated source: 5beta-cholane
annotated property: database_cross_reference
annotated target: Beilstein:2048472
source: Beilstein

Axiom
annotated source: 5beta-cholane
annotated property: has_exact_synonym
annotated target: 5beta-cholane
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

acyl group
type: Class
subclass of: organic group
definition: An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.
has_exact_synonym: acyl group
has_exact_synonym: alkanoyl
has OBO namespace: chebi_ontology
has related synonym: acyl groups
has related synonym: alkanoyl group
has related synonym: groupe acyle
id: CHEBI:22221
in subset: 3 STAR

Axiom
annotated source: acyl group
annotated property: has_exact_synonym
annotated target: acyl group
database_cross_reference: IUPAC

Axiom
annotated source: acyl group
annotated property: has_exact_synonym
annotated target: alkanoyl
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: acyl group
annotated property: hasRelatedSynonym
annotated target: acyl groups
database_cross_reference: ChEBI

Axiom
annotated source: acyl group
annotated property: hasRelatedSynonym
annotated target: alkanoyl group
database_cross_reference: ChEBI

Axiom
annotated source: acyl group
annotated property: hasRelatedSynonym
annotated target: groupe acyle
database_cross_reference: IUPAC

alkali metal atom
type: Class
subclass of: main group element atom
subclass of: metal atom
subclass of: s-block element atom
has_exact_synonym: alkali metals
has OBO namespace: chebi_ontology
has related synonym: Alkalimetall
has related synonym: Alkalimetalle
has related synonym: alkali metal
has related synonym: metal alcalin
has related synonym: metal alcalino
has related synonym: metales alcalinos
has related synonym: metaux alcalins
id: CHEBI:22314
in subset: 3 STAR

Axiom
annotated source: alkali metal atom
annotated property: has_exact_synonym
annotated target: alkali metals
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: alkali metal atom
annotated property: hasRelatedSynonym
annotated target: Alkalimetall
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: hasRelatedSynonym
annotated target: Alkalimetalle
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: hasRelatedSynonym
annotated target: alkali metal
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: hasRelatedSynonym
annotated target: metal alcalin
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: hasRelatedSynonym
annotated target: metal alcalino
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: hasRelatedSynonym
annotated target: metales alcalinos
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: hasRelatedSynonym
annotated target: metaux alcalins
database_cross_reference: ChEBI

alkaloid
type: Class
subclass of: independent continuant
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has role
  some values from: metabolite
definition: Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.
database_cross_reference: Wikipedia:Alkaloid
has_exact_synonym: Alkaloid
has_exact_synonym: alkaloids
has OBO namespace: chebi_ontology
has related synonym: Alkaloide
has related synonym: alcaloide
has related synonym: alcaloides
id: CHEBI:22315
in subset: 3 STAR

Axiom
annotated source: alkaloid
annotated property: has_exact_synonym
annotated target: Alkaloid
database_cross_reference: ChEBI

Axiom
annotated source: alkaloid
annotated property: has_exact_synonym
annotated target: alkaloids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: alkaloid
annotated property: hasRelatedSynonym
annotated target: Alkaloide
database_cross_reference: ChEBI

Axiom
annotated source: alkaloid
annotated property: hasRelatedSynonym
annotated target: alcaloide
database_cross_reference: ChEBI

Axiom
annotated source: alkaloid
annotated property: hasRelatedSynonym
annotated target: alcaloides
database_cross_reference: ChEBI

aminoglycan
type: Class
subclass of: organonitrogen compound
subclass of: polysaccharide derivative
has OBO namespace: chebi_ontology
has related synonym: aminoglycans
id: CHEBI:22506
in subset: 3 STAR

Axiom
annotated source: aminoglycan
annotated property: hasRelatedSynonym
annotated target: aminoglycans
database_cross_reference: ChEBI

anion
type: Class
subclass of: ion
definition: A monoatomic or polyatomic species having one or more elementary charges of the electron.
has_exact_synonym: Anion
has_exact_synonym: anion
has OBO namespace: chebi_ontology
has related synonym: Anionen
has related synonym: aniones
has related synonym: anions
id: CHEBI:22563
in subset: 3 STAR

Axiom
annotated source: anion
annotated property: has_exact_synonym
annotated target: Anion
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: has_exact_synonym
annotated target: anion
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: has_exact_synonym
annotated target: anion
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: anion
annotated property: hasRelatedSynonym
annotated target: Anionen
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: hasRelatedSynonym
annotated target: aniones
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: hasRelatedSynonym
annotated target: anions
database_cross_reference: IUPAC

antioxidant
type: Class
subclass of: chemical role
definition: A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
has OBO namespace: chebi_ontology
has related synonym: antioxidants
has related synonym: antioxydant
has related synonym: antoxidant
id: CHEBI:22586
in subset: 3 STAR

Axiom
annotated source: antioxidant
annotated property: hasRelatedSynonym
annotated target: antioxidants
database_cross_reference: ChEBI

Axiom
annotated source: antioxidant
annotated property: hasRelatedSynonym
annotated target: antioxydant
database_cross_reference: ChEBI

Axiom
annotated source: antioxidant
annotated property: hasRelatedSynonym
annotated target: antoxidant
database_cross_reference: ChEBI

base
type: Class
subclass of: chemical role
definition: A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
database_cross_reference: KEGG:C00701
has_exact_synonym: Base
has_exact_synonym: base
has OBO namespace: chebi_ontology
has related synonym: Base1
has related synonym: Base2
has related synonym: Basen
has related synonym: Nucleobase
has related synonym: bases
id: CHEBI:22695
in subset: 3 STAR

Axiom
annotated source: base
annotated property: has_exact_synonym
annotated target: Base
database_cross_reference: ChEBI

Axiom
annotated source: base
annotated property: has_exact_synonym
annotated target: base
database_cross_reference: ChEBI

Axiom
annotated source: base
annotated property: has_exact_synonym
annotated target: base
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: base
annotated property: hasRelatedSynonym
annotated target: Base1
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: base
annotated property: hasRelatedSynonym
annotated target: Base2
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: base
annotated property: hasRelatedSynonym
annotated target: Basen
database_cross_reference: ChEBI

Axiom
annotated source: base
annotated property: hasRelatedSynonym
annotated target: Nucleobase
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: base
annotated property: hasRelatedSynonym
annotated target: bases
database_cross_reference: ChEBI

benzopyrrole
type: Class
subclass of: organic heterobicyclic compound
subclass of: organonitrogen heterocyclic compound
subclass of: polycyclic heteroarene
has OBO namespace: chebi_ontology
has related synonym: benzopyrroles
id: CHEBI:22728
in subset: 3 STAR

Axiom
annotated source: benzopyrrole
annotated property: hasRelatedSynonym
annotated target: benzopyrroles
database_cross_reference: ChEBI

NMR chemical shift reference compound
type: Class
subclass of: application
subclass of: chemical role
definition: Any compound that produces a peak used as reference frequency in the delta chemical shift scale.
has OBO namespace: chebi_ontology
has related synonym: NMR chemical shift reference compounds
has related synonym: NMR chemical shift standard
has related synonym: NMR chemical shift standards
has related synonym: NMR internal standard
has related synonym: NMR internal standards
has related synonym: NMR reference standard
has related synonym: NMR reference standards
id: CHEBI:228364
in subset: 3 STAR

Axiom
annotated source: NMR chemical shift reference compound
annotated property: hasRelatedSynonym
annotated target: NMR chemical shift reference compounds
database_cross_reference: ChEBI

Axiom
annotated source: NMR chemical shift reference compound
annotated property: hasRelatedSynonym
annotated target: NMR chemical shift standard
database_cross_reference: ChEBI

Axiom
annotated source: NMR chemical shift reference compound
annotated property: hasRelatedSynonym
annotated target: NMR chemical shift standards
database_cross_reference: ChEBI

Axiom
annotated source: NMR chemical shift reference compound
annotated property: hasRelatedSynonym
annotated target: NMR internal standard
database_cross_reference: ChEBI

Axiom
annotated source: NMR chemical shift reference compound
annotated property: hasRelatedSynonym
annotated target: NMR internal standards
database_cross_reference: ChEBI

Axiom
annotated source: NMR chemical shift reference compound
annotated property: hasRelatedSynonym
annotated target: NMR reference standard
database_cross_reference: ChEBI

Axiom
annotated source: NMR chemical shift reference compound
annotated property: hasRelatedSynonym
annotated target: NMR reference standards
database_cross_reference: ChEBI

bile salt
type: Class
subclass of: cholanoid
subclass of: organic sodium salt
definition: A sodium salt of the conjugate of any bile acid with either glycine or taurine.
database_cross_reference: KEGG:C01558
has OBO namespace: chebi_ontology
has related synonym: Bile acid
has related synonym: bile salts
id: CHEBI:22868
in subset: 3 STAR

Axiom
annotated source: bile salt
annotated property: hasRelatedSynonym
annotated target: Bile acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bile salt
annotated property: hasRelatedSynonym
annotated target: bile salts
database_cross_reference: ChEBI

carbamoyl group
type: Class
subclass of: univalent carboacyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carbamic acid
definition: The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid.
database_cross_reference: PMID:24168430
has_exact_synonym: carbamoyl
has OBO namespace: chebi_ontology
has related synonym: -C(O)NH2
has related synonym: -CONH2
has related synonym: aminocarbonyl
has related synonym: carbamyl
has related synonym: carbamyl group
has related synonym: carboxamide
id: CHEBI:23004
in subset: 3 STAR

Axiom
annotated source: carbamoyl group
annotated property: database_cross_reference
annotated target: PMID:24168430
source: Europe PMC

Axiom
annotated source: carbamoyl group
annotated property: has_exact_synonym
annotated target: carbamoyl
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbamoyl group
annotated property: hasRelatedSynonym
annotated target: -C(O)NH2
database_cross_reference: ChEBI

Axiom
annotated source: carbamoyl group
annotated property: hasRelatedSynonym
annotated target: -CONH2
database_cross_reference: IUPAC

Axiom
annotated source: carbamoyl group
annotated property: hasRelatedSynonym
annotated target: aminocarbonyl
database_cross_reference: IUPAC

Axiom
annotated source: carbamoyl group
annotated property: hasRelatedSynonym
annotated target: carbamyl
database_cross_reference: ChEBI

Axiom
annotated source: carbamoyl group
annotated property: hasRelatedSynonym
annotated target: carbamyl group
database_cross_reference: ChEBI

Axiom
annotated source: carbamoyl group
annotated property: hasRelatedSynonym
annotated target: carboxamide
database_cross_reference: IUPAC

carbonyl group
type: Class
subclass of: organodiyl group
has_exact_synonym: carbonyl
has_exact_synonym: carbonyl group
has OBO namespace: chebi_ontology
has related synonym: >C=O
id: CHEBI:23019
in subset: 3 STAR

Axiom
annotated source: carbonyl group
annotated property: has_exact_synonym
annotated target: carbonyl
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbonyl group
annotated property: has_exact_synonym
annotated target: carbonyl group
database_cross_reference: ChEBI

Axiom
annotated source: carbonyl group
annotated property: has_exact_synonym
annotated target: carbonyl group
database_cross_reference: UniProt

Axiom
annotated source: carbonyl group
annotated property: hasRelatedSynonym
annotated target: >C=O
database_cross_reference: IUPAC

cofactor
type: Class
subclass of: biochemical role
definition: An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
database_cross_reference: Wikipedia:Cofactor_(biochemistry)
has_exact_synonym: cofactor
has_exact_synonym: cofactors
has OBO namespace: chebi_ontology
id: CHEBI:23357
in subset: 3 STAR

Axiom
annotated source: cofactor
annotated property: has_exact_synonym
annotated target: cofactor
database_cross_reference: IUPAC

Axiom
annotated source: cofactor
annotated property: has_exact_synonym
annotated target: cofactors
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

molecular entity
type: Class
subclass of: chemical entity
definition: Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
has_exact_synonym: molecular entity
has OBO namespace: chebi_ontology
has related synonym: entidad molecular
has related synonym: entidades moleculares
has related synonym: entite moleculaire
has related synonym: molecular entities
has related synonym: molekulare Entitaet
id: CHEBI:23367
in subset: 3 STAR

Axiom
annotated source: molecular entity
annotated property: has_exact_synonym
annotated target: molecular entity
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: molecular entity
annotated property: hasRelatedSynonym
annotated target: entidad molecular
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: hasRelatedSynonym
annotated target: entidades moleculares
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: hasRelatedSynonym
annotated target: entite moleculaire
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: hasRelatedSynonym
annotated target: molecular entities
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: hasRelatedSynonym
annotated target: molekulare Entitaet
database_cross_reference: ChEBI

cyclic peptide
type: Class
subclass of: peptide
has OBO namespace: chebi_ontology
has related synonym: Cyclopeptid
has related synonym: Zyklopeptid
has related synonym: cyclic peptides
has related synonym: peptide cyclique
has related synonym: peptido ciclico
id: CHEBI:23449
in subset: 3 STAR

Axiom
annotated source: cyclic peptide
annotated property: hasRelatedSynonym
annotated target: Cyclopeptid
database_cross_reference: ChEBI

Axiom
annotated source: cyclic peptide
annotated property: hasRelatedSynonym
annotated target: Zyklopeptid
database_cross_reference: ChEBI

Axiom
annotated source: cyclic peptide
annotated property: hasRelatedSynonym
annotated target: cyclic peptides
database_cross_reference: ChEBI

Axiom
annotated source: cyclic peptide
annotated property: hasRelatedSynonym
annotated target: peptide cyclique
database_cross_reference: IUPAC

Axiom
annotated source: cyclic peptide
annotated property: hasRelatedSynonym
annotated target: peptido ciclico
database_cross_reference: IUPAC

drug
type: Class
subclass of: pharmaceutical
definition: Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
has OBO namespace: chebi_ontology
has related synonym: drugs
has related synonym: medicine
id: CHEBI:23888
in subset: 3 STAR

Axiom
annotated source: drug
annotated property: hasRelatedSynonym
annotated target: drugs
database_cross_reference: ChEBI

Axiom
annotated source: drug
annotated property: hasRelatedSynonym
annotated target: medicine
database_cross_reference: ChEBI

monoatomic cation
type: Class
subclass of: monoatomic ion
subclass of: cation
has OBO namespace: chebi_ontology
has related synonym: monoatomic cations
id: CHEBI:23906
in subset: 3 STAR

Axiom
annotated source: monoatomic cation
annotated property: hasRelatedSynonym
annotated target: monoatomic cations
database_cross_reference: ChEBI

enzyme inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
has_exact_synonym: enzyme inhibitor
has OBO namespace: chebi_ontology
has related synonym: enzyme inhibitors
has related synonym: inhibidor enzimatico
has related synonym: inhibidores enzimaticos
has related synonym: inhibiteur enzymatique
has related synonym: inhibiteurs enzymatiques
id: CHEBI:23924
in subset: 3 STAR

Axiom
annotated source: enzyme inhibitor
annotated property: has_exact_synonym
annotated target: enzyme inhibitor
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: enzyme inhibitor
annotated property: hasRelatedSynonym
annotated target: enzyme inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: hasRelatedSynonym
annotated target: inhibidor enzimatico
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: hasRelatedSynonym
annotated target: inhibidores enzimaticos
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: hasRelatedSynonym
annotated target: inhibiteur enzymatique
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: hasRelatedSynonym
annotated target: inhibiteurs enzymatiques
database_cross_reference: ChEBI

glycogens
type: Class
subclass of: glucan
has OBO namespace: chebi_ontology
id: CHEBI:24384
in subset: 3 STAR

chemical entity
type: Class
definition: A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
has_exact_synonym: chemical entity
has OBO namespace: chebi_ontology
id: CHEBI:24431
in subset: 3 STAR

Axiom
annotated source: chemical entity
annotated property: has_exact_synonym
annotated target: chemical entity
database_cross_reference: UniProt

biological role
type: Class
subclass of: role
definition: A role played by the molecular entity or part thereof within a biological context.
has OBO namespace: chebi_ontology
has related synonym: biological function
id: CHEBI:24432
in subset: 3 STAR

Axiom
annotated source: biological role
annotated property: hasRelatedSynonym
annotated target: biological function
database_cross_reference: ChEBI

group
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: atom
definition: A defined linked collection of atoms or a single atom within a molecular entity.
has_exact_synonym: group
has OBO namespace: chebi_ontology
has related synonym: Gruppe
has related synonym: Rest
has related synonym: groupe
has related synonym: grupo
has related synonym: grupos
id: CHEBI:24433
in subset: 3 STAR

Axiom
annotated source: group
annotated property: has_exact_synonym
annotated target: group
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: group
annotated property: hasRelatedSynonym
annotated target: Gruppe
database_cross_reference: ChEBI

Axiom
annotated source: group
annotated property: hasRelatedSynonym
annotated target: Rest
database_cross_reference: ChEBI

Axiom
annotated source: group
annotated property: hasRelatedSynonym
annotated target: groupe
database_cross_reference: IUPAC

Axiom
annotated source: group
annotated property: hasRelatedSynonym
annotated target: grupo
database_cross_reference: IUPAC

Axiom
annotated source: group
annotated property: hasRelatedSynonym
annotated target: grupos
database_cross_reference: IUPAC

organic heterocyclic compound
type: Class
subclass of: heteroorganic entity
subclass of: organic cyclic compound
subclass of: heterocyclic compound
definition: A cyclic compound having as ring members atoms of carbon and at least of one other element.
has OBO namespace: chebi_ontology
has related synonym: organic heterocycle
has related synonym: organic heterocyclic compounds
id: CHEBI:24532
in subset: 3 STAR

Axiom
annotated source: organic heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: organic heterocycle
database_cross_reference: ChEBI

Axiom
annotated source: organic heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: organic heterocyclic compounds
database_cross_reference: ChEBI

heterodetic cyclic peptide
type: Class
subclass of: cyclic peptide
definition: A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond.
has_exact_synonym: heterodetic cyclic peptide
has OBO namespace: chebi_ontology
has related synonym: heterodetic cyclic peptides
has related synonym: peptide cyclique heterodetique
has related synonym: peptido ciclico heterodetico
id: CHEBI:24533
in subset: 3 STAR

Axiom
annotated source: heterodetic cyclic peptide
annotated property: has_exact_synonym
annotated target: heterodetic cyclic peptide
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: heterodetic cyclic peptide
annotated property: hasRelatedSynonym
annotated target: heterodetic cyclic peptides
database_cross_reference: ChEBI

Axiom
annotated source: heterodetic cyclic peptide
annotated property: hasRelatedSynonym
annotated target: peptide cyclique heterodetique
database_cross_reference: IUPAC

Axiom
annotated source: heterodetic cyclic peptide
annotated property: hasRelatedSynonym
annotated target: peptido ciclico heterodetico
database_cross_reference: IUPAC

hormone
type: Class
subclass of: molecular messenger
subclass of: agonist
definition: Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
has OBO namespace: chebi_ontology
has related synonym: endocrine
has related synonym: hormones
id: CHEBI:24621
in subset: 3 STAR

Axiom
annotated source: hormone
annotated property: hasRelatedSynonym
annotated target: endocrine
database_cross_reference: ChEBI

Axiom
annotated source: hormone
annotated property: hasRelatedSynonym
annotated target: hormones
database_cross_reference: ChEBI

hydroxides
type: Class
subclass of: oxygen molecular entity
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydroxy group
definition: Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).
has OBO namespace: chebi_ontology
id: CHEBI:24651
in subset: 3 STAR

hydroxy-5beta-cholanic acid
type: Class
subclass of: organic hydroxy compound
subclass of: 5beta-cholanic acids
subclass of: Restriction
  on property: has functional parent
  some values from: 5beta-cholanic acid
definition: Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position.
has OBO namespace: chebi_ontology
has related synonym: hydroxy-5beta-cholanic acids
id: CHEBI:24663
in subset: 3 STAR

Axiom
annotated source: hydroxy-5beta-cholanic acid
annotated property: hasRelatedSynonym
annotated target: hydroxy-5beta-cholanic acids
database_cross_reference: ChEBI

indoles
type: Class
subclass of: benzopyrrole
definition: Any compound containing an indole skeleton.
has OBO namespace: chebi_ontology
id: CHEBI:24828
in subset: 3 STAR

oxoacid
type: Class
subclass of: independent continuant
subclass of: hydroxides
subclass of: Restriction
  on property: has role
  some values from: Bronsted acid
definition: A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
has_exact_synonym: oxoacid
has_exact_synonym: oxoacids
has OBO namespace: chebi_ontology
has related synonym: oxacids
has related synonym: oxiacids
has related synonym: oxo acid
has related synonym: oxy-acids
has related synonym: oxyacids
id: CHEBI:24833
in subset: 3 STAR

Axiom
annotated source: oxoacid
annotated property: has_exact_synonym
annotated target: oxoacid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: oxoacid
annotated property: has_exact_synonym
annotated target: oxoacids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: oxoacid
annotated property: hasRelatedSynonym
annotated target: oxacids
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: hasRelatedSynonym
annotated target: oxiacids
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: hasRelatedSynonym
annotated target: oxo acid
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: hasRelatedSynonym
annotated target: oxy-acids
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: hasRelatedSynonym
annotated target: oxyacids
database_cross_reference: ChEBI

inorganic anion
type: Class
subclass of: anion
subclass of: inorganic ion
has OBO namespace: chebi_ontology
has related synonym: inorganic anions
id: CHEBI:24834
in subset: 3 STAR

Axiom
annotated source: inorganic anion
annotated property: hasRelatedSynonym
annotated target: inorganic anions
database_cross_reference: ChEBI

inorganic molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity that contains no carbon.
has OBO namespace: chebi_ontology
has related synonym: anorganische Verbindungen
has related synonym: inorganic compounds
has related synonym: inorganic entity
has related synonym: inorganic molecular entities
has related synonym: inorganics
id: CHEBI:24835
in subset: 3 STAR

Axiom
annotated source: inorganic molecular entity
annotated property: hasRelatedSynonym
annotated target: anorganische Verbindungen
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: hasRelatedSynonym
annotated target: inorganic compounds
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: hasRelatedSynonym
annotated target: inorganic entity
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: hasRelatedSynonym
annotated target: inorganic molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: hasRelatedSynonym
annotated target: inorganics
database_cross_reference: ChEBI

inorganic oxide
type: Class
subclass of: inorganic molecular entity
subclass of: oxide
has OBO namespace: chebi_ontology
has related synonym: inorganic oxides
id: CHEBI:24836
in subset: 3 STAR

Axiom
annotated source: inorganic oxide
annotated property: hasRelatedSynonym
annotated target: inorganic oxides
database_cross_reference: ChEBI

salt
type: Class
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: anion
subclass of: Restriction
  on property: has part
  some values from: cation
definition: A salt is an assembly of cations and anions.
has_exact_synonym: salt
has OBO namespace: chebi_ontology
has related synonym: Salz
has related synonym: Salze
has related synonym: ionic compound
has related synonym: ionic compounds
has related synonym: sal
has related synonym: sales
has related synonym: salts
has related synonym: sel
has related synonym: sels
id: CHEBI:24866
in subset: 3 STAR

Axiom
annotated source: salt
annotated property: has_exact_synonym
annotated target: salt
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: Salz
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: Salze
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: ionic compound
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: ionic compounds
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: sal
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: sales
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: salts
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: sel
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: hasRelatedSynonym
annotated target: sels
database_cross_reference: ChEBI

monoatomic ion
type: Class
subclass of: ion
subclass of: monoatomic entity
has OBO namespace: chebi_ontology
has related synonym: monoatomic ions
id: CHEBI:24867
in subset: 3 STAR

Axiom
annotated source: monoatomic ion
annotated property: hasRelatedSynonym
annotated target: monoatomic ions
database_cross_reference: ChEBI

organic salt
type: Class
subclass of: salt
has OBO namespace: chebi_ontology
has related synonym: organic salts
has related synonym: organisches Salz
id: CHEBI:24868
in subset: 3 STAR

Axiom
annotated source: organic salt
annotated property: hasRelatedSynonym
annotated target: organic salts
database_cross_reference: ChEBI

Axiom
annotated source: organic salt
annotated property: hasRelatedSynonym
annotated target: organisches Salz
database_cross_reference: ChEBI

ion
type: Class
subclass of: molecular entity
definition: A molecular entity having a net electric charge.
has_exact_synonym: Ion
has_exact_synonym: ion
has OBO namespace: chebi_ontology
has related synonym: Ionen
has related synonym: iones
has related synonym: ions
id: CHEBI:24870
in subset: 3 STAR

Axiom
annotated source: ion
annotated property: has_exact_synonym
annotated target: Ion
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: has_exact_synonym
annotated target: ion
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: has_exact_synonym
annotated target: ion
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: ion
annotated property: hasRelatedSynonym
annotated target: Ionen
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: hasRelatedSynonym
annotated target: iones
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: hasRelatedSynonym
annotated target: ions
database_cross_reference: ChEBI

linear tetrapyrrole
type: Class
subclass of: tetrapyrrole
has OBO namespace: chebi_ontology
id: CHEBI:25046
in subset: 1 STAR

metabolite
type: Class
subclass of: biochemical role
definition: Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
has alternative id: CHEBI:26619
has alternative id: CHEBI:35220
has_exact_synonym: metabolite
has OBO namespace: chebi_ontology
has related synonym: metabolites
has related synonym: primary metabolites
has related synonym: secondary metabolites
id: CHEBI:25212
in subset: 3 STAR

Axiom
annotated source: metabolite
annotated property: has_exact_synonym
annotated target: metabolite
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: metabolite
annotated property: hasRelatedSynonym
annotated target: metabolites
database_cross_reference: ChEBI

Axiom
annotated source: metabolite
annotated property: hasRelatedSynonym
annotated target: primary metabolites
database_cross_reference: ChEBI

Axiom
annotated source: metabolite
annotated property: hasRelatedSynonym
annotated target: secondary metabolites
database_cross_reference: ChEBI

metal cation
type: Class
subclass of: monoatomic cation
subclass of: inorganic cation
has OBO namespace: chebi_ontology
has related synonym: a metal cation
has related synonym: metal cations
id: CHEBI:25213
in subset: 3 STAR

Axiom
annotated source: metal cation
annotated property: hasRelatedSynonym
annotated target: a metal cation
database_cross_reference: UniProt

Axiom
annotated source: metal cation
annotated property: hasRelatedSynonym
annotated target: metal cations
database_cross_reference: ChEBI

elemental molecule
type: Class
subclass of: molecule
subclass of: elemental molecular entity
definition: A molecule all atoms of which have the same atomic number.
has OBO namespace: chebi_ontology
has related synonym: homoatomic molecule
has related synonym: homoatomic molecules
id: CHEBI:25362
in subset: 3 STAR

Axiom
annotated source: elemental molecule
annotated property: hasRelatedSynonym
annotated target: homoatomic molecule
database_cross_reference: ChEBI

Axiom
annotated source: elemental molecule
annotated property: hasRelatedSynonym
annotated target: homoatomic molecules
database_cross_reference: ChEBI

molecule
type: Class
subclass of: polyatomic entity
definition: Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.
has_exact_synonym: molecule
has OBO namespace: chebi_ontology
has related synonym: Molekuel
has related synonym: molecula
has related synonym: molecules
has related synonym: neutral molecular compounds
id: CHEBI:25367
in subset: 3 STAR

Axiom
annotated source: molecule
annotated property: has_exact_synonym
annotated target: molecule
database_cross_reference: IUPAC

Axiom
annotated source: molecule
annotated property: hasRelatedSynonym
annotated target: Molekuel
database_cross_reference: ChEBI

Axiom
annotated source: molecule
annotated property: hasRelatedSynonym
annotated target: molecula
database_cross_reference: IUPAC

Axiom
annotated source: molecule
annotated property: hasRelatedSynonym
annotated target: molecules
database_cross_reference: IUPAC

Axiom
annotated source: molecule
annotated property: hasRelatedSynonym
annotated target: neutral molecular compounds
database_cross_reference: IUPAC

monoamine molecular messenger
type: Class
subclass of: monoamine
subclass of: Restriction
  on property: has role
  some values from: molecular messenger
definition: A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
has OBO namespace: chebi_ontology
has related synonym: monamines
has related synonym: monoamines
id: CHEBI:25375
in subset: 3 STAR

Axiom
annotated source: monoamine molecular messenger
annotated property: hasRelatedSynonym
annotated target: monamines
database_cross_reference: ChEBI

Axiom
annotated source: monoamine molecular messenger
annotated property: hasRelatedSynonym
annotated target: monoamines
database_cross_reference: ChEBI

monocarboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: monocarboxylic acid anion
definition: An oxoacid containing a single carboxy group.
has OBO namespace: chebi_ontology
has related synonym: monocarboxylic acids
id: CHEBI:25384
in subset: 3 STAR

Axiom
annotated source: monocarboxylic acid
annotated property: hasRelatedSynonym
annotated target: monocarboxylic acids
database_cross_reference: ChEBI

monoatomic monocation
type: Class
subclass of: monoatomic cation
has OBO namespace: chebi_ontology
has related synonym: monoatomic monocations
has related synonym: monovalent inorganic cations
id: CHEBI:25414
in subset: 3 STAR

Axiom
annotated source: monoatomic monocation
annotated property: hasRelatedSynonym
annotated target: monoatomic monocations
database_cross_reference: ChEBI

Axiom
annotated source: monoatomic monocation
annotated property: hasRelatedSynonym
annotated target: monovalent inorganic cations
database_cross_reference: ChEBI

neurotransmitter
type: Class
subclass of: molecular messenger
definition: An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
database_cross_reference: Wikipedia:Neurotransmitter
has OBO namespace: chebi_ontology
has related synonym: neurotransmitters
id: CHEBI:25512
in subset: 3 STAR

Axiom
annotated source: neurotransmitter
annotated property: hasRelatedSynonym
annotated target: neurotransmitters
database_cross_reference: ChEBI

nitrogen atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: pnictogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
database_cross_reference: WebElements:N
has_exact_synonym: nitrogen
has OBO namespace: chebi_ontology
has related synonym: 7N
has related synonym: N
has related synonym: Stickstoff
has related synonym: azote
has related synonym: nitrogen
has related synonym: nitrogeno
id: CHEBI:25555
in subset: 3 STAR

Axiom
annotated source: nitrogen atom
annotated property: has_exact_synonym
annotated target: nitrogen
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: nitrogen atom
annotated property: hasRelatedSynonym
annotated target: 7N
database_cross_reference: IUPAC

Axiom
annotated source: nitrogen atom
annotated property: hasRelatedSynonym
annotated target: N
database_cross_reference: IUPAC

Axiom
annotated source: nitrogen atom
annotated property: hasRelatedSynonym
annotated target: Stickstoff
database_cross_reference: ChEBI

Axiom
annotated source: nitrogen atom
annotated property: hasRelatedSynonym
annotated target: azote
database_cross_reference: IUPAC

Axiom
annotated source: nitrogen atom
annotated property: hasRelatedSynonym
annotated target: nitrogen
database_cross_reference: ChEBI

Axiom
annotated source: nitrogen atom
annotated property: hasRelatedSynonym
annotated target: nitrogeno
database_cross_reference: ChEBI

nonmetal atom
type: Class
subclass of: atom
has_exact_synonym: nonmetal
has OBO namespace: chebi_ontology
has related synonym: Nichtmetall
has related synonym: Nichtmetalle
has related synonym: no metal
has related synonym: no metales
has related synonym: non-metal
has related synonym: non-metaux
has related synonym: nonmetal
has related synonym: nonmetals
id: CHEBI:25585
in subset: 3 STAR

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: nonmetals
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_exact_synonym
annotated target: nonmetal
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: Nichtmetall
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: Nichtmetalle
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: no metal
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: no metales
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: non-metal
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: non-metaux
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: hasRelatedSynonym
annotated target: nonmetal
database_cross_reference: ChEBI

organic anion
type: Class
subclass of: anion
subclass of: organic ion
definition: Any organic ion with a net negative charge.
has OBO namespace: chebi_ontology
has related synonym: organic anions
id: CHEBI:25696
in subset: 3 STAR

Axiom
annotated source: organic anion
annotated property: hasRelatedSynonym
annotated target: organic anions
database_cross_reference: ChEBI

organic cation
type: Class
subclass of: organic ion
subclass of: cation
definition: Any organic ion with a net positive charge.
has OBO namespace: chebi_ontology
has related synonym: organic cations
id: CHEBI:25697
in subset: 3 STAR

Axiom
annotated source: organic cation
annotated property: hasRelatedSynonym
annotated target: organic cations
database_cross_reference: ChEBI

organic ion
type: Class
subclass of: ion
subclass of: organic molecular entity
has OBO namespace: chebi_ontology
has related synonym: organic ions
id: CHEBI:25699
in subset: 3 STAR

Axiom
annotated source: organic ion
annotated property: hasRelatedSynonym
annotated target: organic ions
database_cross_reference: ChEBI

organic sulfate
type: Class
subclass of: sulfates
subclass of: Restriction
  on property: is conjugate acid of
  some values from: organosulfate oxoanion
definition: Compounds of the general formula SO3HOR where R is an organyl group
has OBO namespace: chebi_ontology
has related synonym: organic sulfates
id: CHEBI:25704
in subset: 3 STAR

Axiom
annotated source: organic sulfate
annotated property: hasRelatedSynonym
annotated target: organic sulfates
database_cross_reference: ChEBI

oxide
type: Class
subclass of: oxygen molecular entity
subclass of: heteroatomic molecular entity
definition: An oxide is a chemical compound of oxygen with other chemical elements.
has_exact_synonym: oxide
has OBO namespace: chebi_ontology
has related synonym: oxides
id: CHEBI:25741
in subset: 3 STAR

Axiom
annotated source: oxide
annotated property: has_exact_synonym
annotated target: oxide
database_cross_reference: ChEBI

Axiom
annotated source: oxide
annotated property: hasRelatedSynonym
annotated target: oxides
database_cross_reference: ChEBI

oxygen atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
database_cross_reference: KEGG:C00007
database_cross_reference: WebElements:O
has_exact_synonym: oxygen
has OBO namespace: chebi_ontology
has related synonym: 8O
has related synonym: O
has related synonym: Sauerstoff
has related synonym: oxigeno
has related synonym: oxygen
has related synonym: oxygene
id: CHEBI:25805
in subset: 3 STAR

Axiom
annotated source: oxygen atom
annotated property: has_exact_synonym
annotated target: oxygen
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: oxygen atom
annotated property: hasRelatedSynonym
annotated target: 8O
database_cross_reference: IUPAC

Axiom
annotated source: oxygen atom
annotated property: hasRelatedSynonym
annotated target: O
database_cross_reference: IUPAC

Axiom
annotated source: oxygen atom
annotated property: hasRelatedSynonym
annotated target: Sauerstoff
database_cross_reference: ChEBI

Axiom
annotated source: oxygen atom
annotated property: hasRelatedSynonym
annotated target: oxigeno
database_cross_reference: ChEBI

Axiom
annotated source: oxygen atom
annotated property: hasRelatedSynonym
annotated target: oxygen
database_cross_reference: ChEBI

Axiom
annotated source: oxygen atom
annotated property: hasRelatedSynonym
annotated target: oxygene
database_cross_reference: ChEBI

oxygen molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: oxygen atom
has_exact_synonym: oxygen molecular entity
has OBO namespace: chebi_ontology
has related synonym: oxygen molecular entities
id: CHEBI:25806
in subset: 3 STAR

Axiom
annotated source: oxygen molecular entity
annotated property: has_exact_synonym
annotated target: oxygen molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: oxygen molecular entity
annotated property: hasRelatedSynonym
annotated target: oxygen molecular entities
database_cross_reference: ChEBI

peptide hormone
type: Class
subclass of: peptide
subclass of: Restriction
  on property: has role
  some values from: hormone
definition: Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine.
has OBO namespace: chebi_ontology
has related synonym: peptide hormones
has related synonym: polypeptide hormone
id: CHEBI:25905
in subset: 3 STAR

Axiom
annotated source: peptide hormone
annotated property: hasRelatedSynonym
annotated target: peptide hormones
database_cross_reference: ChEBI

Axiom
annotated source: peptide hormone
annotated property: hasRelatedSynonym
annotated target: polypeptide hormone
database_cross_reference: ChEBI

sodium atom
type: Class
subclass of: independent continuant
subclass of: alkali metal atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
database_cross_reference: CAS:7440-23-5
database_cross_reference: Gmelin:16221
database_cross_reference: KEGG:C01330
database_cross_reference: WebElements:Na
has_exact_synonym: sodium
has OBO namespace: chebi_ontology
has related synonym: 11Na
has related synonym: Na
has related synonym: Natrium
has related synonym: natrium
has related synonym: sodio
has related synonym: sodium
id: CHEBI:26708
in subset: 3 STAR

Axiom
annotated source: sodium atom
annotated property: database_cross_reference
annotated target: CAS:7440-23-5
source: ChemIDplus

Axiom
annotated source: sodium atom
annotated property: database_cross_reference
annotated target: Gmelin:16221
source: Gmelin

Axiom
annotated source: sodium atom
annotated property: has_exact_synonym
annotated target: sodium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sodium atom
annotated property: hasRelatedSynonym
annotated target: 11Na
database_cross_reference: IUPAC

Axiom
annotated source: sodium atom
annotated property: hasRelatedSynonym
annotated target: Na
database_cross_reference: IUPAC

Axiom
annotated source: sodium atom
annotated property: hasRelatedSynonym
annotated target: Natrium
database_cross_reference: ChemIDplus

Axiom
annotated source: sodium atom
annotated property: hasRelatedSynonym
annotated target: natrium
database_cross_reference: IUPAC

Axiom
annotated source: sodium atom
annotated property: hasRelatedSynonym
annotated target: sodio
database_cross_reference: ChemIDplus

Axiom
annotated source: sodium atom
annotated property: hasRelatedSynonym
annotated target: sodium
database_cross_reference: ChEBI

sodium molecular entity
type: Class
subclass of: alkali metal molecular entity
subclass of: Restriction
  on property: has part
  some values from: sodium atom
has OBO namespace: chebi_ontology
has related synonym: sodium compounds
has related synonym: sodium molecular entities
id: CHEBI:26712
in subset: 3 STAR

Axiom
annotated source: sodium molecular entity
annotated property: hasRelatedSynonym
annotated target: sodium compounds
database_cross_reference: ChEBI

Axiom
annotated source: sodium molecular entity
annotated property: hasRelatedSynonym
annotated target: sodium molecular entities
database_cross_reference: ChEBI

sodium salt
type: Class
subclass of: sodium molecular entity
subclass of: alkali metal salt
subclass of: Restriction
  on property: has part
  some values from: sodium(1+)
definition: Any alkali metal salt having sodium(1+) as the cation.
has OBO namespace: chebi_ontology
has related synonym: Natriumsalz
has related synonym: Natriumsalze
has related synonym: sodium salts
id: CHEBI:26714
in subset: 3 STAR

Axiom
annotated source: sodium salt
annotated property: hasRelatedSynonym
annotated target: Natriumsalz
database_cross_reference: ChEBI

Axiom
annotated source: sodium salt
annotated property: hasRelatedSynonym
annotated target: Natriumsalze
database_cross_reference: ChEBI

Axiom
annotated source: sodium salt
annotated property: hasRelatedSynonym
annotated target: sodium salts
database_cross_reference: ChEBI

steroid hormone
type: Class
subclass of: independent continuant
subclass of: steroid
subclass of: Restriction
  on property: has role
  some values from: hormone
definition: Any steroid that acts as hormone.
has OBO namespace: chebi_ontology
has related synonym: Steroidhormon
has related synonym: Steroidhormone
has related synonym: hormona esteroide
has related synonym: hormonas esteroideas
has related synonym: hormone steroide
has related synonym: hormones steroides
has related synonym: steroid hormones
id: CHEBI:26764
in subset: 3 STAR

Axiom
annotated source: steroid hormone
annotated property: hasRelatedSynonym
annotated target: Steroidhormon
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: hasRelatedSynonym
annotated target: Steroidhormone
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: hasRelatedSynonym
annotated target: hormona esteroide
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: hasRelatedSynonym
annotated target: hormonas esteroideas
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: hasRelatedSynonym
annotated target: hormone steroide
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: hasRelatedSynonym
annotated target: hormones steroides
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: hasRelatedSynonym
annotated target: steroid hormones
database_cross_reference: ChEBI

sulfuric ester
type: Class
subclass of: ester
subclass of: sulfuric acid derivative
definition: An ester of an alcohol and sulfuric acid.
has OBO namespace: chebi_ontology
has related synonym: sulfate ester
has related synonym: sulfuric acid ester
has related synonym: sulfuric acid esters
id: CHEBI:26819
in subset: 3 STAR

Axiom
annotated source: sulfuric ester
annotated property: hasRelatedSynonym
annotated target: sulfate ester
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric ester
annotated property: hasRelatedSynonym
annotated target: sulfuric acid ester
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric ester
annotated property: hasRelatedSynonym
annotated target: sulfuric acid esters
database_cross_reference: ChEBI

sulfates
type: Class
subclass of: sulfuric acid derivative
definition: Salts and esters of sulfuric acid
has_exact_synonym: sulfates
has OBO namespace: chebi_ontology
has related synonym: sulfuric acid derivative
has related synonym: sulphates
id: CHEBI:26820
in subset: 3 STAR

Axiom
annotated source: sulfates
annotated property: has_exact_synonym
annotated target: sulfates
database_cross_reference: ChEBI

Axiom
annotated source: sulfates
annotated property: hasRelatedSynonym
annotated target: sulfuric acid derivative
database_cross_reference: ChEBI

Axiom
annotated source: sulfates
annotated property: hasRelatedSynonym
annotated target: sulphates
database_cross_reference: ChEBI

sulfur atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
database_cross_reference: CAS:7704-34-9
database_cross_reference: KEGG:C00087
database_cross_reference: KEGG:D06527
database_cross_reference: PPDB:605
database_cross_reference: WebElements:S
has_exact_synonym: sulfur
has OBO namespace: chebi_ontology
has related synonym: 16S
has related synonym: Elemental sulfur
has related synonym: S
has related synonym: Schwefel
has related synonym: azufre
has related synonym: soufre
has related synonym: sulfur
has related synonym: sulphur
has related synonym: theion
id: CHEBI:26833
in subset: 3 STAR

Axiom
annotated source: sulfur atom
annotated property: database_cross_reference
annotated target: CAS:7704-34-9
source: ChemIDplus

Axiom
annotated source: sulfur atom
annotated property: database_cross_reference
annotated target: CAS:7704-34-9
source: NIST Chemistry WebBook

Axiom
annotated source: sulfur atom
annotated property: has_exact_synonym
annotated target: sulfur
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: 16S
database_cross_reference: IUPAC

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: Elemental sulfur
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: S
database_cross_reference: IUPAC

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: S
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: Schwefel
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: azufre
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: soufre
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: sulfur
database_cross_reference: UniProt

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: sulphur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: hasRelatedSynonym
annotated target: theion
database_cross_reference: IUPAC

sulfur molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: sulfur atom
has_exact_synonym: sulfur molecular entity
has OBO namespace: chebi_ontology
has related synonym: sulfur molecular entities
id: CHEBI:26835
in subset: 3 STAR

Axiom
annotated source: sulfur molecular entity
annotated property: has_exact_synonym
annotated target: sulfur molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: sulfur molecular entity
annotated property: hasRelatedSynonym
annotated target: sulfur molecular entities
database_cross_reference: ChEBI

sulfuric acid
type: Class
subclass of: sulfur oxoacid
subclass of: Restriction
  on property: has role
  some values from: catalyst
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogensulfate
definition: A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom.
database_cross_reference: CAS:7664-93-9
database_cross_reference: Gmelin:2122
database_cross_reference: KEGG:C00059
database_cross_reference: KEGG:D05963
database_cross_reference: KNApSAcK:C00007530
database_cross_reference: MolBase:4
database_cross_reference: PMID:13568755
database_cross_reference: PMID:16122922
database_cross_reference: PMID:19397353
database_cross_reference: PMID:22047659
database_cross_reference: PMID:22136045
database_cross_reference: PMID:22204399
database_cross_reference: PMID:22267186
database_cross_reference: PMID:22296037
database_cross_reference: PMID:22364556
database_cross_reference: PMID:22435616
database_cross_reference: PPDB:606
database_cross_reference: Reaxys:2037554
database_cross_reference: Wikipedia:Sulfuric_acid
has_exact_synonym: Sulfuric acid
has_exact_synonym: dihydrogen tetraoxosulfate
has_exact_synonym: dihydroxidodioxidosulfur
has_exact_synonym: hydrogen tetraoxosulfate(2-)
has_exact_synonym: hydrogen tetraoxosulfate(VI)
has_exact_synonym: sulfuric acid
has_exact_synonym: tetraoxosulfuric acid
has OBO namespace: chebi_ontology
has related synonym: Acide sulfurique
has related synonym: Acido sulfurico
has related synonym: Acidum sulfuricum
has related synonym: H2SO4
has related synonym: Schwefelsaeureloesungen
has related synonym: [S(OH)2O2]
has related synonym: [SO2(OH)2]
has related synonym: sulphuric acid
id: CHEBI:26836
in subset: 3 STAR

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: CAS:7664-93-9
source: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: CAS:7664-93-9
source: KEGG COMPOUND

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: CAS:7664-93-9
source: NIST Chemistry WebBook

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: Gmelin:2122
source: Gmelin

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:13568755
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:16122922
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:19397353
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22047659
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22136045
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22204399
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22267186
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22296037
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22364556
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22435616
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: Reaxys:2037554
source: Reaxys

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: Sulfuric acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: dihydrogen tetraoxosulfate
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: dihydroxidodioxidosulfur
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: hydrogen tetraoxosulfate(2-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: hydrogen tetraoxosulfate(VI)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: sulfuric acid
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: sulfuric acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: tetraoxosulfuric acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: Acide sulfurique
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: Acido sulfurico
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: Acidum sulfuricum
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: H2SO4
database_cross_reference: IUPAC

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: Schwefelsaeureloesungen
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: [S(OH)2O2]
database_cross_reference: MolBase

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: [SO2(OH)2]
database_cross_reference: IUPAC

Axiom
annotated source: sulfuric acid
annotated property: hasRelatedSynonym
annotated target: sulphuric acid
database_cross_reference: MolBase

tetrapyrrole
type: Class
subclass of: heteroarene
subclass of: polypyrrole
definition: A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
has_exact_synonym: tetrapyrrole
has_exact_synonym: tetrapyrroles
has OBO namespace: chebi_ontology
has related synonym: a tetrapyrrole
id: CHEBI:26932
in subset: 3 STAR

Axiom
annotated source: tetrapyrrole
annotated property: has_exact_synonym
annotated target: tetrapyrrole
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: tetrapyrrole
annotated property: has_exact_synonym
annotated target: tetrapyrroles
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: tetrapyrrole
annotated property: hasRelatedSynonym
annotated target: a tetrapyrrole
database_cross_reference: UniProt

micronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
database_cross_reference: Wikipedia:Micronutrient
has OBO namespace: chebi_ontology
has related synonym: micronutrients
has related synonym: trace elements
id: CHEBI:27027
in subset: 3 STAR

Axiom
annotated source: micronutrient
annotated property: hasRelatedSynonym
annotated target: micronutrients
database_cross_reference: ChEBI

Axiom
annotated source: micronutrient
annotated property: hasRelatedSynonym
annotated target: trace elements
database_cross_reference: ChEBI

tryptamines
type: Class
subclass of: indoles
definition: Tryptamine and its substitution derivatives.
has OBO namespace: chebi_ontology
id: CHEBI:27162
in subset: 3 STAR

organic heterobicyclic compound
type: Class
subclass of: heterobicyclic compound
subclass of: organic heteropolycyclic compound
has OBO namespace: chebi_ontology
has related synonym: heterobicyclic compounds
has related synonym: organic heterobicyclic compounds
id: CHEBI:27171
in subset: 3 STAR

Axiom
annotated source: organic heterobicyclic compound
annotated property: hasRelatedSynonym
annotated target: heterobicyclic compounds
database_cross_reference: ChEBI

Axiom
annotated source: organic heterobicyclic compound
annotated property: hasRelatedSynonym
annotated target: organic heterobicyclic compounds
database_cross_reference: ChEBI

univalent carboacyl group
type: Class
subclass of: carboacyl group
definition: A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.
has OBO namespace: chebi_ontology
has related synonym: univalent acyl group
has related synonym: univalent carboacyl groups
has related synonym: univalent carboxylic acyl groups
id: CHEBI:27207
in subset: 3 STAR

Axiom
annotated source: univalent carboacyl group
annotated property: hasRelatedSynonym
annotated target: univalent acyl group
database_cross_reference: ChEBI

Axiom
annotated source: univalent carboacyl group
annotated property: hasRelatedSynonym
annotated target: univalent carboacyl groups
database_cross_reference: ChEBI

Axiom
annotated source: univalent carboacyl group
annotated property: hasRelatedSynonym
annotated target: univalent carboxylic acyl groups
database_cross_reference: ChEBI

zwitterion
type: Class
subclass of: dipolar compound
definition: A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).
has_exact_synonym: zwitterion
has_exact_synonym: zwitterions
has OBO namespace: chebi_ontology
has related synonym: compose zwitterionique
has related synonym: compuestos zwitterionicos
has related synonym: zwitteriones
has related synonym: zwitterionic compounds
id: CHEBI:27369
in subset: 3 STAR

Axiom
annotated source: zwitterion
annotated property: has_exact_synonym
annotated target: zwitterion
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: zwitterion
annotated property: has_exact_synonym
annotated target: zwitterions
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: zwitterion
annotated property: hasRelatedSynonym
annotated target: compose zwitterionique
database_cross_reference: IUPAC

Axiom
annotated source: zwitterion
annotated property: hasRelatedSynonym
annotated target: compuestos zwitterionicos
database_cross_reference: IUPAC

Axiom
annotated source: zwitterion
annotated property: hasRelatedSynonym
annotated target: zwitteriones
database_cross_reference: IUPAC

Axiom
annotated source: zwitterion
annotated property: hasRelatedSynonym
annotated target: zwitterionic compounds
database_cross_reference: IUPAC

carbon atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: carbon group element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
has alternative id: CHEBI:23009
has alternative id: CHEBI:3399
database_cross_reference: CAS:7440-44-0
database_cross_reference: KEGG:C06265
database_cross_reference: WebElements:C
has_exact_synonym: carbon
has OBO namespace: chebi_ontology
has related synonym: 6C
has related synonym: C
has related synonym: Carbon
has related synonym: Kohlenstoff
has related synonym: carbon
has related synonym: carbone
has related synonym: carbonium
has related synonym: carbono
id: CHEBI:27594
in subset: 3 STAR

Axiom
annotated source: carbon atom
annotated property: database_cross_reference
annotated target: CAS:7440-44-0
source: ChemIDplus

Axiom
annotated source: carbon atom
annotated property: database_cross_reference
annotated target: CAS:7440-44-0
source: KEGG COMPOUND

Axiom
annotated source: carbon atom
annotated property: has_exact_synonym
annotated target: carbon
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: 6C
database_cross_reference: IUPAC

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: C
database_cross_reference: IUPAC

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: C
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: Carbon
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: Kohlenstoff
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: carbon
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: carbone
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: carbonium
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: hasRelatedSynonym
annotated target: carbono
database_cross_reference: ChEBI

glycogen
type: Class
subclass of: independent continuant
subclass of: glycogens
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
definition: A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.
has alternative id: CHEBI:24379
has alternative id: CHEBI:5466
database_cross_reference: CAS:9005-79-2
database_cross_reference: GlyGen:G99991IU
database_cross_reference: GlyTouCan:G99991IU
database_cross_reference: HMDB:HMDB0000757
database_cross_reference: KEGG:C00182
database_cross_reference: MetaCyc:CPD0-971
database_cross_reference: Wikipedia:Glycogen
has_exact_synonym: Glycogen
has OBO namespace: chebi_ontology
has related synonym: WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1
has related synonym: animal starch
has related synonym: liver starch
id: CHEBI:28087
in subset: 3 STAR

Axiom
annotated source: glycogen
annotated property: database_cross_reference
annotated target: CAS:9005-79-2
source: ChemIDplus

Axiom
annotated source: glycogen
annotated property: database_cross_reference
annotated target: CAS:9005-79-2
source: KEGG COMPOUND

Axiom
annotated source: glycogen
annotated property: has_exact_synonym
annotated target: Glycogen
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glycogen
annotated property: hasRelatedSynonym
annotated target: WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1
database_cross_reference: GlyTouCan

Axiom
annotated source: glycogen
annotated property: hasRelatedSynonym
annotated target: animal starch
database_cross_reference: ChemIDplus

Axiom
annotated source: glycogen
annotated property: hasRelatedSynonym
annotated target: liver starch
database_cross_reference: ChemIDplus

carbamic acid
type: Class
subclass of: organonitrogen compound
subclass of: carbon oxoacid
subclass of: one-carbon compound
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbamate
definition: A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.
has alternative id: CHEBI:22504
has alternative id: CHEBI:23002
has alternative id: CHEBI:3386
has alternative id: CHEBI:44573
database_cross_reference: Beilstein:1734754
database_cross_reference: CAS:463-77-4
database_cross_reference: DrugBank:DB04261
database_cross_reference: Gmelin:130345
database_cross_reference: KEGG:C01563
database_cross_reference: PDBeChem:OUT
database_cross_reference: Wikipedia:Carbamic_acid
has_exact_synonym: CARBAMIC ACID
has_exact_synonym: Carbamic acid
has_exact_synonym: carbamic acid
has OBO namespace: chebi_ontology
has related synonym: Aminoameisensaeure
has related synonym: Aminoformic acid
has related synonym: Carbamate
has related synonym: Carbamidsaeure
id: CHEBI:28616
in subset: 3 STAR

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: Beilstein:1734754
source: Beilstein

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: CAS:463-77-4
source: ChemIDplus

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: CAS:463-77-4
source: KEGG COMPOUND

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: Gmelin:130345
source: Gmelin

Axiom
annotated source: carbamic acid
annotated property: has_exact_synonym
annotated target: CARBAMIC ACID
database_cross_reference: PDBeChem

Axiom
annotated source: carbamic acid
annotated property: has_exact_synonym
annotated target: Carbamic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbamic acid
annotated property: has_exact_synonym
annotated target: carbamic acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbamic acid
annotated property: hasRelatedSynonym
annotated target: Aminoameisensaeure
database_cross_reference: ChEBI

Axiom
annotated source: carbamic acid
annotated property: hasRelatedSynonym
annotated target: Aminoformic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbamic acid
annotated property: hasRelatedSynonym
annotated target: Carbamate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbamic acid
annotated property: hasRelatedSynonym
annotated target: Carbamidsaeure
database_cross_reference: ChEBI

serotonin
type: Class
subclass of: monoamine molecular messenger
subclass of: tryptamines
subclass of: phenols
subclass of: primary amino compound
subclass of: hydroxyindoles
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: has functional parent
  some values from: tryptamine
subclass of: Restriction
  on property: is conjugate base of
  some values from: serotonin(1+)
definition: A primary amino compound that is the 5-hydroxy derivative of tryptamine.
has alternative id: CHEBI:1420
has alternative id: CHEBI:26652
has alternative id: CHEBI:49894
database_cross_reference: CAS:50-67-9
database_cross_reference: Gmelin:1861995
database_cross_reference: HMDB:HMDB0000259
database_cross_reference: KEGG:C00780
database_cross_reference: KNApSAcK:C00001429
database_cross_reference: LINCS:LSM-6589
database_cross_reference: MetaCyc:SEROTONIN
database_cross_reference: PDBeChem:SRO
database_cross_reference: PMID:18593914
database_cross_reference: PMID:22770225
database_cross_reference: PMID:24136337
database_cross_reference: Reaxys:143524
database_cross_reference: Wikipedia:Serotonin
has_exact_synonym: 3-(2-aminoethyl)-1H-indol-5-ol
has_exact_synonym: SEROTONIN
has_exact_synonym: Serotonin
has OBO namespace: chebi_ontology
has related synonym: 3-(2-Aminoethyl)-1H-indol-5-ol
has related synonym: 5-HT
has related synonym: 5-Hydroxytryptamine
has related synonym: Enteramine
has related synonym: serotonine
has related synonym: thrombocytin
has related synonym: thrombotonin
id: CHEBI:28790
in subset: 3 STAR

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: CAS:50-67-9
source: ChemIDplus

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: CAS:50-67-9
source: KEGG COMPOUND

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: Gmelin:1861995
source: Gmelin

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: PMID:18593914
source: Europe PMC

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: PMID:22770225
source: Europe PMC

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: PMID:24136337
source: Europe PMC

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: Reaxys:143524
source: Reaxys

Axiom
annotated source: serotonin
annotated property: has_exact_synonym
annotated target: 3-(2-aminoethyl)-1H-indol-5-ol
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: serotonin
annotated property: has_exact_synonym
annotated target: SEROTONIN
database_cross_reference: PDBeChem

Axiom
annotated source: serotonin
annotated property: has_exact_synonym
annotated target: Serotonin
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: hasRelatedSynonym
annotated target: 3-(2-Aminoethyl)-1H-indol-5-ol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: hasRelatedSynonym
annotated target: 5-HT
database_cross_reference: IUPHAR

Axiom
annotated source: serotonin
annotated property: hasRelatedSynonym
annotated target: 5-Hydroxytryptamine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: hasRelatedSynonym
annotated target: Enteramine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: hasRelatedSynonym
annotated target: serotonine
database_cross_reference: ChEBI

Axiom
annotated source: serotonin
annotated property: hasRelatedSynonym
annotated target: thrombocytin
database_cross_reference: ChemIDplus

Axiom
annotated source: serotonin
annotated property: hasRelatedSynonym
annotated target: thrombotonin
database_cross_reference: ChemIDplus

ammonium
type: Class
subclass of: independent continuant
subclass of: nitrogen hydride
subclass of: onium cation
subclass of: monovalent inorganic cation
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: ammonia
definition: An onium cation obtained by protonation of ammonia.
has alternative id: CHEBI:22534
has alternative id: CHEBI:49783
has alternative id: CHEBI:7435
database_cross_reference: CAS:14798-03-9
database_cross_reference: Gmelin:84
database_cross_reference: KEGG:C01342
database_cross_reference: MetaCyc:AMMONIUM
database_cross_reference: MolBase:929
database_cross_reference: PDBeChem:NH4
database_cross_reference: PMID:11319011
database_cross_reference: PMID:11341317
database_cross_reference: PMID:12096804
database_cross_reference: PMID:14512268
database_cross_reference: PMID:14879753
database_cross_reference: PMID:16345391
database_cross_reference: PMID:16903292
database_cross_reference: PMID:17392693
database_cross_reference: PMID:18515490
database_cross_reference: PMID:19199063
database_cross_reference: PMID:19596600
database_cross_reference: PMID:19682559
database_cross_reference: PMID:19716251
database_cross_reference: PMID:21993530
database_cross_reference: PMID:22265469
database_cross_reference: PMID:22524020
database_cross_reference: PMID:22562341
database_cross_reference: PMID:22631217
database_cross_reference: Reaxys:16093784
database_cross_reference: Wikipedia:Ammonium
has_exact_synonym: ammonium
has_exact_synonym: azanium
has OBO namespace: chebi_ontology
has related synonym: Ammonium(1+)
has related synonym: NH4(+)
has related synonym: NH4+
has related synonym: [NH4](+)
has related synonym: ammonium cation
has related synonym: ammonium ion
id: CHEBI:28938
in subset: 3 STAR

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: CAS:14798-03-9
source: ChemIDplus

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: CAS:14798-03-9
source: NIST Chemistry WebBook

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: Gmelin:84
source: Gmelin

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:11319011
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:11341317
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:12096804
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:14512268
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:14879753
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:16345391
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:16903292
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:17392693
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:18515490
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19199063
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19596600
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19682559
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19716251
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:21993530
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22265469
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22524020
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22562341
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22631217
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: Reaxys:16093784
source: Reaxys

Axiom
annotated source: ammonium
annotated property: has_exact_synonym
annotated target: ammonium
database_cross_reference: ChEBI

Axiom
annotated source: ammonium
annotated property: has_exact_synonym
annotated target: ammonium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: ammonium
annotated property: has_exact_synonym
annotated target: azanium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: ammonium
annotated property: hasRelatedSynonym
annotated target: Ammonium(1+)
database_cross_reference: ChemIDplus

Axiom
annotated source: ammonium
annotated property: hasRelatedSynonym
annotated target: NH4(+)
database_cross_reference: IUPAC

Axiom
annotated source: ammonium
annotated property: hasRelatedSynonym
annotated target: NH4(+)
database_cross_reference: UniProt

Axiom
annotated source: ammonium
annotated property: hasRelatedSynonym
annotated target: NH4+
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ammonium
annotated property: hasRelatedSynonym
annotated target: [NH4](+)
database_cross_reference: MolBase

Axiom
annotated source: ammonium
annotated property: hasRelatedSynonym
annotated target: ammonium cation
database_cross_reference: ChemIDplus

Axiom
annotated source: ammonium
annotated property: hasRelatedSynonym
annotated target: ammonium ion
database_cross_reference: PDBeChem

dicarboxylic acid dianion
type: Class
subclass of: dicarboxylic acid anion
subclass of: carboxylic acid dianion
definition: A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid.
has alternative id: CHEBI:13632
has alternative id: CHEBI:23688
has alternative id: CHEBI:23689
has alternative id: CHEBI:38711
has_exact_synonym: dicarboxylic acid dianion
has OBO namespace: chebi_ontology
has related synonym: a dicarboxylate
has related synonym: dicarboxylate
has related synonym: dicarboxylates
has related synonym: dicarboxylic acid dianions
id: CHEBI:28965
in subset: 3 STAR

Axiom
annotated source: dicarboxylic acid dianion
annotated property: has_exact_synonym
annotated target: dicarboxylic acid dianion
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid dianion
annotated property: hasRelatedSynonym
annotated target: a dicarboxylate
database_cross_reference: UniProt

Axiom
annotated source: dicarboxylic acid dianion
annotated property: hasRelatedSynonym
annotated target: dicarboxylate
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid dianion
annotated property: hasRelatedSynonym
annotated target: dicarboxylates
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid dianion
annotated property: hasRelatedSynonym
annotated target: dicarboxylic acid dianions
database_cross_reference: ChEBI

carbonic acid
type: Class
subclass of: carbon oxoacid
subclass of: chalcocarbonic acid
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogencarbonate
has alternative id: CHEBI:13351
has alternative id: CHEBI:23017
has alternative id: CHEBI:23744
has alternative id: CHEBI:3401
database_cross_reference: CAS:463-79-6
database_cross_reference: Gmelin:25554
database_cross_reference: KEGG:C01353
database_cross_reference: PDBeChem:CO3
has_exact_synonym: Carbonic acid
has_exact_synonym: carbonic acid
has_exact_synonym: dihydroxidooxidocarbon
has OBO namespace: chebi_ontology
has related synonym: Dihydrogen carbonate
has related synonym: H2CO3
has related synonym: Koehlensaeure
has related synonym: [CO(OH)2]
id: CHEBI:28976
in subset: 3 STAR

Axiom
annotated source: carbonic acid
annotated property: database_cross_reference
annotated target: CAS:463-79-6
source: ChemIDplus

Axiom
annotated source: carbonic acid
annotated property: database_cross_reference
annotated target: CAS:463-79-6
source: KEGG COMPOUND

Axiom
annotated source: carbonic acid
annotated property: database_cross_reference
annotated target: Gmelin:25554
source: Gmelin

Axiom
annotated source: carbonic acid
annotated property: has_exact_synonym
annotated target: Carbonic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbonic acid
annotated property: has_exact_synonym
annotated target: carbonic acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbonic acid
annotated property: has_exact_synonym
annotated target: dihydroxidooxidocarbon
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbonic acid
annotated property: hasRelatedSynonym
annotated target: Dihydrogen carbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbonic acid
annotated property: hasRelatedSynonym
annotated target: H2CO3
database_cross_reference: IUPAC

Axiom
annotated source: carbonic acid
annotated property: hasRelatedSynonym
annotated target: H2CO3
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbonic acid
annotated property: hasRelatedSynonym
annotated target: Koehlensaeure
database_cross_reference: ChEBI

Axiom
annotated source: carbonic acid
annotated property: hasRelatedSynonym
annotated target: [CO(OH)2]
database_cross_reference: IUPAC

carboxylic acid anion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carboxylic acid
definition: The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
has alternative id: CHEBI:13626
has alternative id: CHEBI:13945
has alternative id: CHEBI:23026
has alternative id: CHEBI:58657
has OBO namespace: chebi_ontology
has related synonym: a carboxylate
has related synonym: carboxylic acid anions
has related synonym: carboxylic anions
id: CHEBI:29067
in subset: 3 STAR

Axiom
annotated source: carboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: a carboxylate
database_cross_reference: UniProt

Axiom
annotated source: carboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: carboxylic acid anions
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: carboxylic anions
database_cross_reference: ChEBI

sodium(1+)
type: Class
subclass of: independent continuant
subclass of: monoatomic monocation
subclass of: alkali metal cation
subclass of: elemental sodium
subclass of: monovalent inorganic cation
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: human metabolite
definition: A monoatomic monocation obtained from sodium.
has alternative id: CHEBI:26717
has alternative id: CHEBI:49766
has alternative id: CHEBI:9175
database_cross_reference: CAS:17341-25-2
database_cross_reference: Gmelin:15196
database_cross_reference: KEGG:C01330
database_cross_reference: PDBeChem:NA
has_exact_synonym: sodium cation
has_exact_synonym: sodium(1+)
has_exact_synonym: sodium(1+) ion
has_exact_synonym: sodium(I) cation
has OBO namespace: chebi_ontology
has related synonym: Na(+)
has related synonym: Na+
has related synonym: SODIUM ION
id: CHEBI:29101
in subset: 3 STAR

Axiom
annotated source: sodium(1+)
annotated property: database_cross_reference
annotated target: CAS:17341-25-2
source: ChemIDplus

Axiom
annotated source: sodium(1+)
annotated property: database_cross_reference
annotated target: CAS:17341-25-2
source: NIST Chemistry WebBook

Axiom
annotated source: sodium(1+)
annotated property: database_cross_reference
annotated target: Gmelin:15196
source: Gmelin

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium cation
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium(1+)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium(1+) ion
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium(I) cation
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: hasRelatedSynonym
annotated target: Na(+)
database_cross_reference: IUPAC

Axiom
annotated source: sodium(1+)
annotated property: hasRelatedSynonym
annotated target: Na(+)
database_cross_reference: UniProt

Axiom
annotated source: sodium(1+)
annotated property: hasRelatedSynonym
annotated target: Na+
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sodium(1+)
annotated property: hasRelatedSynonym
annotated target: SODIUM ION
database_cross_reference: PDBeChem

azanide
type: Class
subclass of: nitrogen hydride
subclass of: monovalent inorganic anion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydridonitrate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: ammonia
has_exact_synonym: amide
has_exact_synonym: azanide
has_exact_synonym: dihydridonitrate(1-)
has OBO namespace: chebi_ontology
has related synonym: NH2(-)
id: CHEBI:29337
in subset: 3 STAR

Axiom
annotated source: azanide
annotated property: has_exact_synonym
annotated target: amide
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: azanide
annotated property: has_exact_synonym
annotated target: azanide
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: azanide
annotated property: has_exact_synonym
annotated target: dihydridonitrate(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: azanide
annotated property: hasRelatedSynonym
annotated target: NH2(-)
database_cross_reference: IUPAC

hydridonitrate(2-)
type: Class
subclass of: nitrogen hydride
subclass of: divalent inorganic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: azanide
definition: A divalent inorganic anion resulting from the removal of two protons from ammonia.
has_exact_synonym: azanediide
has_exact_synonym: hydridonitrate(2-)
has OBO namespace: chebi_ontology
has related synonym: NH(2-)
has related synonym: imide
id: CHEBI:29340
in subset: 3 STAR

Axiom
annotated source: hydridonitrate(2-)
annotated property: has_exact_synonym
annotated target: azanediide
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydridonitrate(2-)
annotated property: has_exact_synonym
annotated target: hydridonitrate(2-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydridonitrate(2-)
annotated property: hasRelatedSynonym
annotated target: NH(2-)
database_cross_reference: IUPAC

Axiom
annotated source: hydridonitrate(2-)
annotated property: hasRelatedSynonym
annotated target: imide
database_cross_reference: IUPAC

hydridodioxygen(1+)
type: Class
subclass of: oxygen hydride
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dioxygen
database_cross_reference: Gmelin:508
has_exact_synonym: dioxidenium
has_exact_synonym: hydridodioxygen(1+)
has OBO namespace: chebi_ontology
has related synonym: HO2(+)
has related synonym: HOO(+)
has related synonym: [HO2](+)
id: CHEBI:29793
in subset: 3 STAR

Axiom
annotated source: hydridodioxygen(1+)
annotated property: database_cross_reference
annotated target: Gmelin:508
source: Gmelin

Axiom
annotated source: hydridodioxygen(1+)
annotated property: has_exact_synonym
annotated target: dioxidenium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydridodioxygen(1+)
annotated property: has_exact_synonym
annotated target: hydridodioxygen(1+)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydridodioxygen(1+)
annotated property: hasRelatedSynonym
annotated target: HO2(+)
database_cross_reference: IUPAC

Axiom
annotated source: hydridodioxygen(1+)
annotated property: hasRelatedSynonym
annotated target: HOO(+)
database_cross_reference: ChEBI

Axiom
annotated source: hydridodioxygen(1+)
annotated property: hasRelatedSynonym
annotated target: [HO2](+)
database_cross_reference: ChEBI

acetate
type: Class
subclass of: independent continuant
subclass of: monocarboxylic acid anion
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: acetic acid
definition: A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.
has alternative id: CHEBI:13704
has alternative id: CHEBI:22165
has alternative id: CHEBI:40480
database_cross_reference: CAS:71-50-1
database_cross_reference: DrugBank:DB03166
database_cross_reference: Gmelin:1379
database_cross_reference: KEGG:C00033
database_cross_reference: MetaCyc:ACET
database_cross_reference: PDBeChem:ACT
database_cross_reference: PMID:17190852
database_cross_reference: PMID:22211106
database_cross_reference: PMID:22371380
database_cross_reference: Reaxys:1901470
database_cross_reference: UM-BBD_compID:c0050
database_cross_reference: Wikipedia:Acetate
has_exact_synonym: acetate
has OBO namespace: chebi_ontology
has related synonym: ACETATE ION
has related synonym: Azetat
has related synonym: CH3-COO(-)
has related synonym: Ethanoat
has related synonym: MeCO2 anion
has related synonym: acetic acid, ion(1-)
has related synonym: ethanoate
id: CHEBI:30089
in subset: 3 STAR

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: CAS:71-50-1
source: ChemIDplus

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: CAS:71-50-1
source: NIST Chemistry WebBook

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: Gmelin:1379
source: Gmelin

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: PMID:17190852
source: Europe PMC

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: PMID:22211106
source: Europe PMC

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: PMID:22371380
source: Europe PMC

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: Reaxys:1901470
source: Reaxys

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: UM-BBD_compID:c0050
source: UM-BBD

Axiom
annotated source: acetate
annotated property: has_exact_synonym
annotated target: acetate
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: acetate
annotated property: has_exact_synonym
annotated target: acetate
database_cross_reference: UniProt

Axiom
annotated source: acetate
annotated property: hasRelatedSynonym
annotated target: ACETATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: acetate
annotated property: hasRelatedSynonym
annotated target: Azetat
database_cross_reference: ChEBI

Axiom
annotated source: acetate
annotated property: hasRelatedSynonym
annotated target: CH3-COO(-)
database_cross_reference: IUPAC

Axiom
annotated source: acetate
annotated property: hasRelatedSynonym
annotated target: Ethanoat
database_cross_reference: ChEBI

Axiom
annotated source: acetate
annotated property: hasRelatedSynonym
annotated target: MeCO2 anion
database_cross_reference: NIST_Chemistry_WebBook

Axiom
annotated source: acetate
annotated property: hasRelatedSynonym
annotated target: acetic acid, ion(1-)
database_cross_reference: ChemIDplus

Axiom
annotated source: acetate
annotated property: hasRelatedSynonym
annotated target: ethanoate
database_cross_reference: ChEBI

photon
type: Class
subclass of: boson
definition: Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force.
has alternative id: CHEBI:10581
has alternative id: CHEBI:14383
database_cross_reference: KEGG:C00205
has_exact_synonym: photon
has OBO namespace: chebi_ontology
has related synonym: Lichtquant
has related synonym: Light
has related synonym: foton
has related synonym: gamma
has related synonym: hnu
has related synonym: light quantum
id: CHEBI:30212
in subset: 3 STAR

Axiom
annotated source: photon
annotated property: has_exact_synonym
annotated target: photon
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: photon
annotated property: hasRelatedSynonym
annotated target: Lichtquant
database_cross_reference: ChEBI

Axiom
annotated source: photon
annotated property: hasRelatedSynonym
annotated target: Light
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: photon
annotated property: hasRelatedSynonym
annotated target: foton
database_cross_reference: ChEBI

Axiom
annotated source: photon
annotated property: hasRelatedSynonym
annotated target: gamma
database_cross_reference: IUPAC

Axiom
annotated source: photon
annotated property: hasRelatedSynonym
annotated target: hnu
database_cross_reference: IUPAC

Axiom
annotated source: photon
annotated property: hasRelatedSynonym
annotated target: hnu
database_cross_reference: UniProt

Axiom
annotated source: photon
annotated property: hasRelatedSynonym
annotated target: light quantum
database_cross_reference: ChEBI

bile acid
type: Class
subclass of: bile acids
subclass of: hydroxy-5beta-cholanic acid
definition: Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration.
database_cross_reference: KEGG:C01558
has_exact_synonym: Bile acid
has OBO namespace: chebi_ontology
has related synonym: 5beta-bile acid
has related synonym: 5beta-bile acids
has related synonym: Bile salt
has related synonym: Gallensaeure
has related synonym: Gallensaeuren
has related synonym: bile acids
id: CHEBI:3098
in subset: 3 STAR

Axiom
annotated source: bile acid
annotated property: has_exact_synonym
annotated target: Bile acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bile acid
annotated property: hasRelatedSynonym
annotated target: 5beta-bile acid
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: hasRelatedSynonym
annotated target: 5beta-bile acids
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: hasRelatedSynonym
annotated target: Bile salt
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bile acid
annotated property: hasRelatedSynonym
annotated target: Gallensaeure
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: hasRelatedSynonym
annotated target: Gallensaeuren
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: hasRelatedSynonym
annotated target: bile acids
database_cross_reference: ChEBI

amine
type: Class
subclass of: organic amino compound
definition: A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
has alternative id: CHEBI:13814
has alternative id: CHEBI:22474
has alternative id: CHEBI:2641
database_cross_reference: KEGG:C00706
has_exact_synonym: Amine
has_exact_synonym: amines
has OBO namespace: chebi_ontology
has related synonym: Amin
has related synonym: Substituted amine
id: CHEBI:32952
in subset: 3 STAR

Axiom
annotated source: amine
annotated property: has_exact_synonym
annotated target: Amine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: amine
annotated property: has_exact_synonym
annotated target: amines
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: amine
annotated property: hasRelatedSynonym
annotated target: Amin
database_cross_reference: ChEBI

Axiom
annotated source: amine
annotated property: hasRelatedSynonym
annotated target: Substituted amine
database_cross_reference: KEGG_COMPOUND

amide
type: Class
subclass of: nitrogen molecular entity
definition: An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
has alternative id: CHEBI:22473
has alternative id: CHEBI:2633
database_cross_reference: KEGG:C00241
has_exact_synonym: Amide
has_exact_synonym: amides
has OBO namespace: chebi_ontology
id: CHEBI:32988
in subset: 3 STAR

Axiom
annotated source: amide
annotated property: has_exact_synonym
annotated target: Amide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: amide
annotated property: has_exact_synonym
annotated target: amides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

application
type: Class
subclass of: role
definition: Intended use of the molecular entity or part thereof by humans.
has OBO namespace: chebi_ontology
id: CHEBI:33232
in subset: 3 STAR

fundamental particle
type: Class
subclass of: subatomic particle
definition: A particle not known to have substructure.
has_exact_synonym: elementary particle
has OBO namespace: chebi_ontology
has related synonym: elementary particles
id: CHEBI:33233
in subset: 3 STAR

Axiom
annotated source: fundamental particle
annotated property: has_exact_synonym
annotated target: elementary particle
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: fundamental particle
annotated property: hasRelatedSynonym
annotated target: elementary particles
database_cross_reference: ChEBI

monoatomic entity
type: Class
subclass of: elemental molecular entity
definition: A monoatomic entity is a molecular entity consisting of a single atom.
has OBO namespace: chebi_ontology
has related synonym: atomic entity
has related synonym: monoatomic entities
id: CHEBI:33238
in subset: 3 STAR

Axiom
annotated source: monoatomic entity
annotated property: hasRelatedSynonym
annotated target: atomic entity
database_cross_reference: ChEBI

Axiom
annotated source: monoatomic entity
annotated property: hasRelatedSynonym
annotated target: monoatomic entities
database_cross_reference: ChEBI

oxoacid derivative
type: Class
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has functional parent
  some values from: oxoacid
has OBO namespace: chebi_ontology
has related synonym: oxoacid derivatives
id: CHEBI:33241
in subset: 3 STAR

Axiom
annotated source: oxoacid derivative
annotated property: hasRelatedSynonym
annotated target: oxoacid derivatives
database_cross_reference: ChEBI

inorganic hydride
type: Class
subclass of: inorganic molecular entity
subclass of: hydrides
has OBO namespace: chebi_ontology
has related synonym: inorganic hydrides
id: CHEBI:33242
in subset: 3 STAR

Axiom
annotated source: inorganic hydride
annotated property: hasRelatedSynonym
annotated target: inorganic hydrides
database_cross_reference: ChEBI

organic fundamental parent
type: Class
subclass of: organic hydride
subclass of: organic molecular entity
definition: An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.
has OBO namespace: chebi_ontology
has related synonym: organic fundamental parents
has related synonym: organic parent hydrides
id: CHEBI:33245
in subset: 3 STAR

Axiom
annotated source: organic fundamental parent
annotated property: hasRelatedSynonym
annotated target: organic fundamental parents
database_cross_reference: ChEBI

Axiom
annotated source: organic fundamental parent
annotated property: hasRelatedSynonym
annotated target: organic parent hydrides
database_cross_reference: ChEBI

inorganic group
type: Class
subclass of: group
definition: Any substituent group which does not contain carbon.
has OBO namespace: chebi_ontology
has related synonym: inorganic groups
id: CHEBI:33246
in subset: 3 STAR

Axiom
annotated source: inorganic group
annotated property: hasRelatedSynonym
annotated target: inorganic groups
database_cross_reference: ChEBI

organic group
type: Class
subclass of: group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: organic anionic group
subclass of: Restriction
  on property: is conjugate base of
  some values from: organic cationic group
definition: Any substituent group or skeleton containing carbon.
has OBO namespace: chebi_ontology
has related synonym: organic groups
id: CHEBI:33247
in subset: 3 STAR

Axiom
annotated source: organic group
annotated property: hasRelatedSynonym
annotated target: organic groups
database_cross_reference: ChEBI

organyl group
type: Class
subclass of: organic univalent group
definition: Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.
has_exact_synonym: organyl group
has_exact_synonym: organyl groups
has OBO namespace: chebi_ontology
has related synonym: groupe organyle
has related synonym: grupo organilo
has related synonym: grupos organilo
id: CHEBI:33249
in subset: 3 STAR

Axiom
annotated source: organyl group
annotated property: has_exact_synonym
annotated target: organyl group
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: organyl group
annotated property: has_exact_synonym
annotated target: organyl groups
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: organyl group
annotated property: hasRelatedSynonym
annotated target: groupe organyle
database_cross_reference: IUPAC

Axiom
annotated source: organyl group
annotated property: hasRelatedSynonym
annotated target: grupo organilo
database_cross_reference: IUPAC

Axiom
annotated source: organyl group
annotated property: hasRelatedSynonym
annotated target: grupos organilo
database_cross_reference: IUPAC

atom
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: electron
subclass of: Restriction
  on property: has part
  some values from: atomic nucleus
definition: A chemical entity constituting the smallest component of an element having the chemical properties of the element.
has alternative id: CHEBI:22671
has alternative id: CHEBI:23907
has_exact_synonym: atom
has OBO namespace: chebi_ontology
has related synonym: atome
has related synonym: atomo
has related synonym: atoms
has related synonym: atomus
has related synonym: element
has related synonym: elements
id: CHEBI:33250
in subset: 3 STAR

Axiom
annotated source: atom
annotated property: has_exact_synonym
annotated target: atom
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: atom
annotated property: hasRelatedSynonym
annotated target: atome
database_cross_reference: IUPAC

Axiom
annotated source: atom
annotated property: hasRelatedSynonym
annotated target: atomo
database_cross_reference: IUPAC

Axiom
annotated source: atom
annotated property: hasRelatedSynonym
annotated target: atoms
database_cross_reference: ChEBI

Axiom
annotated source: atom
annotated property: hasRelatedSynonym
annotated target: atomus
database_cross_reference: ChEBI

Axiom
annotated source: atom
annotated property: hasRelatedSynonym
annotated target: element
database_cross_reference: ChEBI

Axiom
annotated source: atom
annotated property: hasRelatedSynonym
annotated target: elements
database_cross_reference: ChEBI

atomic nucleus
type: Class
subclass of: nuclear particle
subclass of: Restriction
  on property: has part
  some values from: nucleon
definition: A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
has_exact_synonym: nucleus
has OBO namespace: chebi_ontology
has related synonym: Atomkern
has related synonym: Kern
has related synonym: noyau
has related synonym: noyau atomique
has related synonym: nuclei
has related synonym: nucleo
has related synonym: nucleo atomico
has related synonym: nucleus atomi
id: CHEBI:33252
in subset: 3 STAR

Axiom
annotated source: atomic nucleus
annotated property: has_exact_synonym
annotated target: nucleus
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: Atomkern
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: Kern
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: noyau
database_cross_reference: IUPAC

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: noyau atomique
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: nuclei
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: nucleo
database_cross_reference: IUPAC

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: nucleo atomico
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: hasRelatedSynonym
annotated target: nucleus atomi
database_cross_reference: ChEBI

nucleon
type: Class
subclass of: baryon
subclass of: nuclear particle
definition: Heavy nuclear particle: proton or neutron.
has_exact_synonym: nucleon
has OBO namespace: chebi_ontology
has related synonym: Nukleon
has related synonym: Nukleonen
has related synonym: nucleons
id: CHEBI:33253
in subset: 3 STAR

Axiom
annotated source: nucleon
annotated property: has_exact_synonym
annotated target: nucleon
database_cross_reference: IUPAC

Axiom
annotated source: nucleon
annotated property: has_exact_synonym
annotated target: nucleon
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: nucleon
annotated property: hasRelatedSynonym
annotated target: Nukleon
database_cross_reference: ChEBI

Axiom
annotated source: nucleon
annotated property: hasRelatedSynonym
annotated target: Nukleonen
database_cross_reference: ChEBI

Axiom
annotated source: nucleon
annotated property: hasRelatedSynonym
annotated target: nucleons
database_cross_reference: ChEBI

primary amide
type: Class
subclass of: amide
definition: A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
has_exact_synonym: primary amide
has_exact_synonym: primary amides
has OBO namespace: chebi_ontology
id: CHEBI:33256
in subset: 3 STAR

Axiom
annotated source: primary amide
annotated property: has_exact_synonym
annotated target: primary amide
database_cross_reference: IUPAC

Axiom
annotated source: primary amide
annotated property: has_exact_synonym
annotated target: primary amides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

elemental molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity all atoms of which have the same atomic number.
has OBO namespace: chebi_ontology
has related synonym: homoatomic entity
has related synonym: homoatomic molecular entities
has related synonym: homoatomic molecular entity
id: CHEBI:33259
in subset: 3 STAR

Axiom
annotated source: elemental molecular entity
annotated property: hasRelatedSynonym
annotated target: homoatomic entity
database_cross_reference: ChEBI

Axiom
annotated source: elemental molecular entity
annotated property: hasRelatedSynonym
annotated target: homoatomic molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: elemental molecular entity
annotated property: hasRelatedSynonym
annotated target: homoatomic molecular entity
database_cross_reference: ChEBI

elemental oxygen
type: Class
subclass of: inorganic molecular entity
subclass of: oxygen molecular entity
subclass of: elemental molecular entity
has OBO namespace: chebi_ontology
id: CHEBI:33262
in subset: 3 STAR

diatomic oxygen
type: Class
subclass of: elemental oxygen
has OBO namespace: chebi_ontology
id: CHEBI:33263
in subset: 3 STAR

polyatomic anion
type: Class
subclass of: anion
subclass of: polyatomic ion
definition: An anion consisting of more than one atom.
has OBO namespace: chebi_ontology
has related synonym: polyatomic anions
id: CHEBI:33273
in subset: 3 STAR

Axiom
annotated source: polyatomic anion
annotated property: hasRelatedSynonym
annotated target: polyatomic anions
database_cross_reference: ChEBI

molecular messenger
type: Class
subclass of: biological role
has OBO namespace: chebi_ontology
has related synonym: chemical messenger
id: CHEBI:33280
in subset: 3 STAR

Axiom
annotated source: molecular messenger
annotated property: hasRelatedSynonym
annotated target: chemical messenger
database_cross_reference: ChEBI

antimicrobial agent
type: Class
subclass of: biological role
definition: A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
has alternative id: CHEBI:22582
database_cross_reference: PMID:12964249
database_cross_reference: PMID:22117953
database_cross_reference: PMID:22439833
database_cross_reference: PMID:22849268
database_cross_reference: PMID:22849276
database_cross_reference: PMID:22958833
has OBO namespace: chebi_ontology
has related synonym: Antibiotika
has related synonym: Antibiotikum
has related synonym: antibiotic
has related synonym: antibiotics
has related synonym: antibiotique
has related synonym: antimicrobial
has related synonym: antimicrobial agents
has related synonym: antimicrobials
has related synonym: microbicide
has related synonym: microbicides
id: CHEBI:33281
in subset: 3 STAR

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:12964249
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22117953
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22439833
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22849268
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22849276
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22958833
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: Antibiotika
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: Antibiotikum
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: antibiotic
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: antibiotics
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: antibiotique
database_cross_reference: IUPAC

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: antimicrobial
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: antimicrobial agents
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: antimicrobials
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: microbicide
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: hasRelatedSynonym
annotated target: microbicides
database_cross_reference: ChEBI

nutrient
type: Class
subclass of: food component
definition: A nutrient is a food component that an organism uses to survive and grow.
has OBO namespace: chebi_ontology
has related synonym: nutrients
id: CHEBI:33284
in subset: 3 STAR

Axiom
annotated source: nutrient
annotated property: hasRelatedSynonym
annotated target: nutrients
database_cross_reference: ChEBI

heteroorganic entity
type: Class
subclass of: organic molecular entity
definition: A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
has OBO namespace: chebi_ontology
has related synonym: heteroorganic entities
has related synonym: organoelement compounds
id: CHEBI:33285
in subset: 3 STAR

Axiom
annotated source: heteroorganic entity
annotated property: hasRelatedSynonym
annotated target: heteroorganic entities
database_cross_reference: ChEBI

Axiom
annotated source: heteroorganic entity
annotated property: hasRelatedSynonym
annotated target: organoelement compounds
database_cross_reference: ChEBI

alkali metal molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: alkali metal atom
definition: A molecular entity containing one or more atoms of an alkali metal.
has OBO namespace: chebi_ontology
has related synonym: alkali metal molecular entities
id: CHEBI:33296
in subset: 3 STAR

Axiom
annotated source: alkali metal molecular entity
annotated property: hasRelatedSynonym
annotated target: alkali metal molecular entities
database_cross_reference: ChEBI

pnictogen
type: Class
subclass of: p-block element atom
definition: Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.
has_exact_synonym: pnictogens
has OBO namespace: chebi_ontology
has related synonym: group 15 elements
has related synonym: group V elements
has related synonym: nitrogenoideos
has related synonym: nitrogenoides
has related synonym: pnictogene
has related synonym: pnictogenes
id: CHEBI:33300
in subset: 3 STAR

Axiom
annotated source: pnictogen
annotated property: has_exact_synonym
annotated target: pnictogens
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: pnictogen
annotated property: hasRelatedSynonym
annotated target: group 15 elements
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: hasRelatedSynonym
annotated target: group V elements
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: hasRelatedSynonym
annotated target: nitrogenoideos
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: hasRelatedSynonym
annotated target: nitrogenoides
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: hasRelatedSynonym
annotated target: pnictogene
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: hasRelatedSynonym
annotated target: pnictogenes
database_cross_reference: ChEBI

pnictogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: pnictogen
definition: A p-block molecular entity containing any pnictogen.
has_exact_synonym: pnictogen molecular entity
has OBO namespace: chebi_ontology
has related synonym: pnictogen molecular entities
id: CHEBI:33302
in subset: 3 STAR

Axiom
annotated source: pnictogen molecular entity
annotated property: has_exact_synonym
annotated target: pnictogen molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen molecular entity
annotated property: hasRelatedSynonym
annotated target: pnictogen molecular entities
database_cross_reference: ChEBI

chalcogen
type: Class
subclass of: p-block element atom
definition: Any p-block element belonging to the group 16 family of the periodic table.
database_cross_reference: PMID:17084588
has_exact_synonym: chalcogen
has_exact_synonym: chalcogens
has OBO namespace: chebi_ontology
has related synonym: Chalkogen
has related synonym: Chalkogene
has related synonym: anfigeno
has related synonym: anfigenos
has related synonym: calcogeno
has related synonym: calcogenos
has related synonym: chalcogene
has related synonym: chalcogenes
has related synonym: group 16 elements
has related synonym: group VI elements
id: CHEBI:33303
in subset: 3 STAR

Axiom
annotated source: chalcogen
annotated property: database_cross_reference
annotated target: PMID:17084588
source: Europe PMC

Axiom
annotated source: chalcogen
annotated property: has_exact_synonym
annotated target: chalcogen
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: chalcogen
annotated property: has_exact_synonym
annotated target: chalcogens
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: Chalkogen
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: Chalkogene
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: anfigeno
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: anfigenos
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: calcogeno
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: calcogenos
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: chalcogene
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: chalcogenes
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: group 16 elements
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: hasRelatedSynonym
annotated target: group VI elements
database_cross_reference: ChEBI

chalcogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: chalcogen
definition: Any p-block molecular entity containing a chalcogen.
has_exact_synonym: chalcogen molecular entity
has OBO namespace: chebi_ontology
has related synonym: chalcogen compounds
has related synonym: chalcogen molecular entities
id: CHEBI:33304
in subset: 3 STAR

Axiom
annotated source: chalcogen molecular entity
annotated property: has_exact_synonym
annotated target: chalcogen molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen molecular entity
annotated property: hasRelatedSynonym
annotated target: chalcogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen molecular entity
annotated property: hasRelatedSynonym
annotated target: chalcogen molecular entities
database_cross_reference: ChEBI

carbon group element atom
type: Class
subclass of: p-block element atom
has_exact_synonym: group 14 elements
has OBO namespace: chebi_ontology
has related synonym: carbon group element
has related synonym: carbon group elements
has related synonym: carbonoides
has related synonym: cristallogene
has related synonym: cristallogenes
has related synonym: group IV elements
id: CHEBI:33306
in subset: 3 STAR

Axiom
annotated source: carbon group element atom
annotated property: has_exact_synonym
annotated target: group 14 elements
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbon group element atom
annotated property: hasRelatedSynonym
annotated target: carbon group element
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: hasRelatedSynonym
annotated target: carbon group elements
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: hasRelatedSynonym
annotated target: carbonoides
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: hasRelatedSynonym
annotated target: cristallogene
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: hasRelatedSynonym
annotated target: cristallogenes
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: hasRelatedSynonym
annotated target: group IV elements
database_cross_reference: ChEBI

carboxylic ester
type: Class
subclass of: ester
subclass of: carbonyl compound
definition: An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.
has alternative id: CHEBI:13204
has alternative id: CHEBI:23028
has alternative id: CHEBI:3408
database_cross_reference: KEGG:C02391
database_cross_reference: Wikipedia:Ester
has_exact_synonym: Carboxylic ester
has_exact_synonym: carboxylic esters
has OBO namespace: chebi_ontology
has related synonym: a carboxylic ester
has related synonym: carboxylic acid esters
id: CHEBI:33308
in subset: 3 STAR

Axiom
annotated source: carboxylic ester
annotated property: has_exact_synonym
annotated target: Carboxylic ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carboxylic ester
annotated property: has_exact_synonym
annotated target: carboxylic esters
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carboxylic ester
annotated property: hasRelatedSynonym
annotated target: a carboxylic ester
database_cross_reference: UniProt

Axiom
annotated source: carboxylic ester
annotated property: hasRelatedSynonym
annotated target: carboxylic acid esters
database_cross_reference: ChEBI

main group element atom
type: Class
subclass of: atom
definition: An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.
has_exact_synonym: main group elements
has OBO namespace: chebi_ontology
has related synonym: Hauptgruppenelement
has related synonym: Hauptgruppenelemente
has related synonym: main group element
id: CHEBI:33318
in subset: 3 STAR

Axiom
annotated source: main group element atom
annotated property: has_exact_synonym
annotated target: main group elements
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: main group element atom
annotated property: hasRelatedSynonym
annotated target: Hauptgruppenelement
database_cross_reference: ChEBI

Axiom
annotated source: main group element atom
annotated property: hasRelatedSynonym
annotated target: Hauptgruppenelemente
database_cross_reference: ChEBI

Axiom
annotated source: main group element atom
annotated property: hasRelatedSynonym
annotated target: main group element
database_cross_reference: ChEBI

sulfur oxoacid
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoacid
has OBO namespace: chebi_ontology
has related synonym: oxoacids of sulfur
has related synonym: sulfur oxoacids
id: CHEBI:33402
in subset: 3 STAR

Axiom
annotated source: sulfur oxoacid
annotated property: hasRelatedSynonym
annotated target: oxoacids of sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoacid
annotated property: hasRelatedSynonym
annotated target: sulfur oxoacids
database_cross_reference: ChEBI

sulfur oxoacid derivative
type: Class
subclass of: sulfur molecular entity
subclass of: oxoacid derivative
has_exact_synonym: sulfur oxoacid derivative
has OBO namespace: chebi_ontology
has related synonym: sulfur oxoacid derivatives
id: CHEBI:33424
in subset: 3 STAR

Axiom
annotated source: sulfur oxoacid derivative
annotated property: has_exact_synonym
annotated target: sulfur oxoacid derivative
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoacid derivative
annotated property: hasRelatedSynonym
annotated target: sulfur oxoacid derivatives
database_cross_reference: ChEBI

sulfur oxoanion
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoanion
has_exact_synonym: sulfur oxoanion
has OBO namespace: chebi_ontology
has related synonym: oxoanions of sulfur
has related synonym: sulfur oxoanions
id: CHEBI:33482
in subset: 3 STAR

Axiom
annotated source: sulfur oxoanion
annotated property: has_exact_synonym
annotated target: sulfur oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoanion
annotated property: hasRelatedSynonym
annotated target: oxoanions of sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoanion
annotated property: hasRelatedSynonym
annotated target: sulfur oxoanions
database_cross_reference: ChEBI

chalcogen oxoacid
type: Class
subclass of: oxoacid
subclass of: Restriction
  on property: has role
  some values from: inorganic acid
has_exact_synonym: chalcogen oxoacid
has OBO namespace: chebi_ontology
has related synonym: chalcogen oxoacids
id: CHEBI:33484
in subset: 3 STAR

Axiom
annotated source: chalcogen oxoacid
annotated property: has_exact_synonym
annotated target: chalcogen oxoacid
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen oxoacid
annotated property: hasRelatedSynonym
annotated target: chalcogen oxoacids
database_cross_reference: ChEBI

chalcogen oxoanion
type: Class
subclass of: oxoanion
has_exact_synonym: chalcogen oxoanion
has OBO namespace: chebi_ontology
has related synonym: chalcogen oxoanions
id: CHEBI:33485
in subset: 3 STAR

Axiom
annotated source: chalcogen oxoanion
annotated property: has_exact_synonym
annotated target: chalcogen oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen oxoanion
annotated property: hasRelatedSynonym
annotated target: chalcogen oxoanions
database_cross_reference: ChEBI

alkali metal cation
type: Class
subclass of: metal cation
has OBO namespace: chebi_ontology
has related synonym: alkali metal cations
id: CHEBI:33504
in subset: 3 STAR

Axiom
annotated source: alkali metal cation
annotated property: hasRelatedSynonym
annotated target: alkali metal cations
database_cross_reference: ChEBI

metal atom
type: Class
subclass of: atom
definition: An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.
has alternative id: CHEBI:25217
has alternative id: CHEBI:6788
database_cross_reference: KEGG:C00050
database_cross_reference: PMID:21784043
database_cross_reference: Wikipedia:Metal
has OBO namespace: chebi_ontology
has related synonym: elemental metal
has related synonym: elemental metals
has related synonym: metal element
has related synonym: metal elements
has related synonym: metals
id: CHEBI:33521
in subset: 3 STAR

Axiom
annotated source: metal atom
annotated property: database_cross_reference
annotated target: PMID:21784043
source: Europe PMC

Axiom
annotated source: metal atom
annotated property: hasRelatedSynonym
annotated target: elemental metal
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: hasRelatedSynonym
annotated target: elemental metals
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: hasRelatedSynonym
annotated target: metal element
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: hasRelatedSynonym
annotated target: metal elements
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: hasRelatedSynonym
annotated target: metals
database_cross_reference: ChEBI

alpha-amino-acid anion
type: Class
subclass of: amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: alpha-amino acid
definition: An amino-acid anion obtained by deprotonation of any alpha-amino acid.
has OBO namespace: chebi_ontology
has related synonym: alpha-amino acid anion
has related synonym: alpha-amino acid anions
has related synonym: alpha-amino-acid anions
id: CHEBI:33558
in subset: 3 STAR

Axiom
annotated source: alpha-amino-acid anion
annotated property: hasRelatedSynonym
annotated target: alpha-amino acid anion
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid anion
annotated property: hasRelatedSynonym
annotated target: alpha-amino acid anions
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid anion
annotated property: hasRelatedSynonym
annotated target: alpha-amino-acid anions
database_cross_reference: ChEBI

s-block element atom
type: Class
subclass of: atom
has OBO namespace: chebi_ontology
has related synonym: s-block element
has related synonym: s-block elements
id: CHEBI:33559
in subset: 3 STAR

Axiom
annotated source: s-block element atom
annotated property: hasRelatedSynonym
annotated target: s-block element
database_cross_reference: ChEBI

Axiom
annotated source: s-block element atom
annotated property: hasRelatedSynonym
annotated target: s-block elements
database_cross_reference: ChEBI

p-block element atom
type: Class
subclass of: main group element atom
definition: Any main group element atom belonging to the p-block of the periodic table.
has OBO namespace: chebi_ontology
has related synonym: p-block element
has related synonym: p-block elements
id: CHEBI:33560
in subset: 3 STAR

Axiom
annotated source: p-block element atom
annotated property: hasRelatedSynonym
annotated target: p-block element
database_cross_reference: ChEBI

Axiom
annotated source: p-block element atom
annotated property: hasRelatedSynonym
annotated target: p-block elements
database_cross_reference: ChEBI

catechols
type: Class
subclass of: benzenediols
definition: Any compound containing an o-diphenol component.
has alternative id: CHEBI:134187
has alternative id: CHEBI:13628
has alternative id: CHEBI:18862
database_cross_reference: KEGG:C15571
has OBO namespace: chebi_ontology
has related synonym: 1,2-benzenediols
has related synonym: a catechol
has related synonym: benzene-1,2-diols
id: CHEBI:33566
in subset: 3 STAR

Axiom
annotated source: catechols
annotated property: hasRelatedSynonym
annotated target: 1,2-benzenediols
database_cross_reference: ChEBI

Axiom
annotated source: catechols
annotated property: hasRelatedSynonym
annotated target: a catechol
database_cross_reference: UniProt

Axiom
annotated source: catechols
annotated property: hasRelatedSynonym
annotated target: benzene-1,2-diols
database_cross_reference: ChEBI

catecholamine
type: Class
subclass of: monoamine molecular messenger
subclass of: catechols
definition: 4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
has alternative id: CHEBI:23056
has alternative id: CHEBI:3468
database_cross_reference: KEGG:C02012
has_exact_synonym: Catecholamine
has_exact_synonym: catecholamines
has OBO namespace: chebi_ontology
has related synonym: catecholamines
id: CHEBI:33567
in subset: 3 STAR

Axiom
annotated source: catecholamine
annotated property: has_exact_synonym
annotated target: Catecholamine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: catecholamine
annotated property: has_exact_synonym
annotated target: catecholamines
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: catecholamine
annotated property: hasRelatedSynonym
annotated target: catecholamines
database_cross_reference: ChEBI

noradrenaline
type: Class
subclass of: catecholamine
subclass of: Restriction
  on property: has role
  some values from: human xenobiotic metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: noradrenaline(1+)
definition: A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted.
database_cross_reference: Beilstein:2210994
database_cross_reference: CAS:138-65-8
database_cross_reference: Gmelin:863925
database_cross_reference: LINCS:LSM-5181
has_exact_synonym: 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
has OBO namespace: chebi_ontology
has related synonym: noradrenalina
has related synonym: norepinephrine
id: CHEBI:33569
in subset: 3 STAR

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: Beilstein:2210994
source: Beilstein

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: CAS:138-65-8
source: ChemIDplus

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: CAS:138-65-8
source: NIST Chemistry WebBook

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: Gmelin:863925
source: Gmelin

Axiom
annotated source: noradrenaline
annotated property: has_exact_synonym
annotated target: 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: noradrenaline
annotated property: hasRelatedSynonym
annotated target: noradrenalina
database_cross_reference: ChEBI

Axiom
annotated source: noradrenaline
annotated property: hasRelatedSynonym
annotated target: norepinephrine
database_cross_reference: ChEBI

benzenediols
type: Class
subclass of: phenols
has alternative id: CHEBI:22705
has alternative id: CHEBI:22711
has OBO namespace: chebi_ontology
id: CHEBI:33570
in subset: 3 STAR

(S)-noradrenaline
type: Class
subclass of: noradrenaline
subclass of: Restriction
  on property: is enantiomer of
  some values from: (R)-noradrenaline
definition: The S-enantiomer of noradrenaline.
database_cross_reference: LINCS:LSM-37072
database_cross_reference: Reaxys:2937999
has_exact_synonym: 4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol
has OBO namespace: chebi_ontology
id: CHEBI:33571
in subset: 3 STAR

Axiom
annotated source: (S)-noradrenaline
annotated property: database_cross_reference
annotated target: Reaxys:2937999
source: Reaxys

Axiom
annotated source: (S)-noradrenaline
annotated property: has_exact_synonym
annotated target: 4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

carboxylic acid
type: Class
subclass of: carbon oxoacid
subclass of: carbonyl compound
subclass of: organic acid
subclass of: Restriction
  on property: has part
  some values from: carboxy group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carboxylic acid anion
definition: A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
has alternative id: CHEBI:13428
has alternative id: CHEBI:13627
has alternative id: CHEBI:23027
database_cross_reference: PMID:17147560
database_cross_reference: PMID:18433345
database_cross_reference: Wikipedia:Carboxylic_acid
has_exact_synonym: carboxylic acid
has_exact_synonym: carboxylic acids
has OBO namespace: chebi_ontology
has related synonym: Carbonsaeure
has related synonym: Carbonsaeuren
has related synonym: Karbonsaeure
has related synonym: RC(=O)OH
has related synonym: acide carboxylique
has related synonym: acides carboxyliques
has related synonym: acido carboxilico
has related synonym: acidos carboxilicos
id: CHEBI:33575
in subset: 3 STAR

Axiom
annotated source: carboxylic acid
annotated property: database_cross_reference
annotated target: PMID:17147560
source: Europe PMC

Axiom
annotated source: carboxylic acid
annotated property: database_cross_reference
annotated target: PMID:18433345
source: Europe PMC

Axiom
annotated source: carboxylic acid
annotated property: has_exact_synonym
annotated target: carboxylic acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carboxylic acid
annotated property: has_exact_synonym
annotated target: carboxylic acids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: Carbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: Carbonsaeuren
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: Karbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: RC(=O)OH
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: acide carboxylique
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: acides carboxyliques
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: acido carboxilico
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: hasRelatedSynonym
annotated target: acidos carboxilicos
database_cross_reference: IUPAC

main group molecular entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: main group element atom
definition: A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.
has OBO namespace: chebi_ontology
has related synonym: main group compounds
has related synonym: main group molecular entities
id: CHEBI:33579
in subset: 3 STAR

Axiom
annotated source: main group molecular entity
annotated property: hasRelatedSynonym
annotated target: main group compounds
database_cross_reference: ChEBI

Axiom
annotated source: main group molecular entity
annotated property: hasRelatedSynonym
annotated target: main group molecular entities
database_cross_reference: ChEBI

carbon group molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon group element atom
has_exact_synonym: carbon group molecular entity
has OBO namespace: chebi_ontology
has related synonym: carbon group molecular entities
id: CHEBI:33582
in subset: 3 STAR

Axiom
annotated source: carbon group molecular entity
annotated property: has_exact_synonym
annotated target: carbon group molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: carbon group molecular entity
annotated property: hasRelatedSynonym
annotated target: carbon group molecular entities
database_cross_reference: ChEBI

cyclic compound
type: Class
subclass of: molecule
definition: Any molecule that consists of a series of atoms joined together to form a ring.
database_cross_reference: Wikipedia:Cyclic_compound
has OBO namespace: chebi_ontology
has related synonym: cyclic compounds
id: CHEBI:33595
in subset: 3 STAR

Axiom
annotated source: cyclic compound
annotated property: hasRelatedSynonym
annotated target: cyclic compounds
database_cross_reference: ChEBI

hydrogen molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydrogen atom
has OBO namespace: chebi_ontology
has related synonym: hydrogen compounds
has related synonym: hydrogen molecular entities
id: CHEBI:33608
in subset: 3 STAR

Axiom
annotated source: hydrogen molecular entity
annotated property: hasRelatedSynonym
annotated target: hydrogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen molecular entity
annotated property: hasRelatedSynonym
annotated target: hydrogen molecular entities
database_cross_reference: ChEBI

polycyclic compound
type: Class
subclass of: cyclic compound
has OBO namespace: chebi_ontology
has related synonym: polycyclic compounds
id: CHEBI:33635
in subset: 3 STAR

Axiom
annotated source: polycyclic compound
annotated property: hasRelatedSynonym
annotated target: polycyclic compounds
database_cross_reference: ChEBI

bicyclic compound
type: Class
subclass of: cyclic compound
definition: A molecule that features two fused rings.
has OBO namespace: chebi_ontology
has related synonym: bicyclic compounds
id: CHEBI:33636
in subset: 3 STAR

Axiom
annotated source: bicyclic compound
annotated property: hasRelatedSynonym
annotated target: bicyclic compounds
database_cross_reference: ChEBI

aromatic compound
type: Class
subclass of: cyclic compound
definition: A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.
has_exact_synonym: aromatic compounds
has_exact_synonym: aromatic molecular entity
has OBO namespace: chebi_ontology
has related synonym: aromatics
has related synonym: aromatische Verbindungen
id: CHEBI:33655
in subset: 3 STAR

Axiom
annotated source: aromatic compound
annotated property: has_exact_synonym
annotated target: aromatic compounds
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: aromatic compound
annotated property: has_exact_synonym
annotated target: aromatic molecular entity
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: aromatic compound
annotated property: hasRelatedSynonym
annotated target: aromatics
database_cross_reference: ChEBI

Axiom
annotated source: aromatic compound
annotated property: hasRelatedSynonym
annotated target: aromatische Verbindungen
database_cross_reference: ChEBI

organic aromatic compound
type: Class
subclass of: aromatic compound
subclass of: organic cyclic compound
has OBO namespace: chebi_ontology
has related synonym: organic aromatic compounds
id: CHEBI:33659
in subset: 3 STAR

Axiom
annotated source: organic aromatic compound
annotated property: hasRelatedSynonym
annotated target: organic aromatic compounds
database_cross_reference: ChEBI

heteropolycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: heterocyclic compound
definition: A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.
has_exact_synonym: heteropolycyclic compounds
has OBO namespace: chebi_ontology
has related synonym: polyheterocyclic compounds
id: CHEBI:33671
in subset: 3 STAR

Axiom
annotated source: heteropolycyclic compound
annotated property: has_exact_synonym
annotated target: heteropolycyclic compounds
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: heteropolycyclic compound
annotated property: hasRelatedSynonym
annotated target: polyheterocyclic compounds
database_cross_reference: ChEBI

heterobicyclic compound
type: Class
subclass of: bicyclic compound
subclass of: heterocyclic compound
definition: A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom.
has_exact_synonym: heterobicyclic compounds
has OBO namespace: chebi_ontology
id: CHEBI:33672
in subset: 3 STAR

Axiom
annotated source: heterobicyclic compound
annotated property: has_exact_synonym
annotated target: heterobicyclic compounds
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

s-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: s-block element atom
definition: An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.
has_exact_synonym: s-block molecular entity
has OBO namespace: chebi_ontology
has related synonym: s-block compounds
has related synonym: s-block molecular entities
id: CHEBI:33674
in subset: 3 STAR

Axiom
annotated source: s-block molecular entity
annotated property: has_exact_synonym
annotated target: s-block molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: s-block molecular entity
annotated property: hasRelatedSynonym
annotated target: s-block compounds
database_cross_reference: ChEBI

Axiom
annotated source: s-block molecular entity
annotated property: hasRelatedSynonym
annotated target: s-block molecular entities
database_cross_reference: ChEBI

p-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: p-block element atom
definition: A main group molecular entity that contains one or more atoms of a p-block element.
has OBO namespace: chebi_ontology
has related synonym: p-block compounds
has related synonym: p-block molecular entities
has related synonym: p-block molecular entitiy
id: CHEBI:33675
in subset: 3 STAR

Axiom
annotated source: p-block molecular entity
annotated property: hasRelatedSynonym
annotated target: p-block compounds
database_cross_reference: ChEBI

Axiom
annotated source: p-block molecular entity
annotated property: hasRelatedSynonym
annotated target: p-block molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: p-block molecular entity
annotated property: hasRelatedSynonym
annotated target: p-block molecular entitiy
database_cross_reference: ChEBI

hydrides
type: Class
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
definition: Hydrides are chemical compounds of hydrogen with other chemical elements.
has OBO namespace: chebi_ontology
id: CHEBI:33692
in subset: 3 STAR

oxygen hydride
type: Class
subclass of: chalcogen hydride
has_exact_synonym: oxygen hydride
has OBO namespace: chebi_ontology
has related synonym: hydrides of oxygen
has related synonym: oxygen hydrides
id: CHEBI:33693
in subset: 3 STAR

Axiom
annotated source: oxygen hydride
annotated property: has_exact_synonym
annotated target: oxygen hydride
database_cross_reference: ChEBI

Axiom
annotated source: oxygen hydride
annotated property: hasRelatedSynonym
annotated target: hydrides of oxygen
database_cross_reference: ChEBI

Axiom
annotated source: oxygen hydride
annotated property: hasRelatedSynonym
annotated target: oxygen hydrides
database_cross_reference: ChEBI

biomacromolecule
type: Class
subclass of: macromolecule
subclass of: organic molecular entity
definition: A macromolecule formed by a living organism.
has_exact_synonym: biopolymer
has OBO namespace: chebi_ontology
has related synonym: Biopolymere
has related synonym: biomacromolecules
has related synonym: biopolymers
id: CHEBI:33694
in subset: 3 STAR

Axiom
annotated source: biomacromolecule
annotated property: has_exact_synonym
annotated target: biopolymer
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: biomacromolecule
annotated property: hasRelatedSynonym
annotated target: Biopolymere
database_cross_reference: ChEBI

Axiom
annotated source: biomacromolecule
annotated property: hasRelatedSynonym
annotated target: biomacromolecules
database_cross_reference: ChEBI

Axiom
annotated source: biomacromolecule
annotated property: hasRelatedSynonym
annotated target: biopolymers
database_cross_reference: ChEBI

information biomacromolecule
type: Class
subclass of: biomacromolecule
has OBO namespace: chebi_ontology
has related synonym: genetically encoded biomacromolecules
has related synonym: genetically encoded biopolymers
has related synonym: information biomacromolecules
has related synonym: information biopolymers
has related synonym: information macromolecule
has related synonym: information macromolecules
id: CHEBI:33695
in subset: 3 STAR

Axiom
annotated source: information biomacromolecule
annotated property: hasRelatedSynonym
annotated target: genetically encoded biomacromolecules
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: hasRelatedSynonym
annotated target: genetically encoded biopolymers
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: hasRelatedSynonym
annotated target: information biomacromolecules
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: hasRelatedSynonym
annotated target: information biopolymers
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: hasRelatedSynonym
annotated target: information macromolecule
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: hasRelatedSynonym
annotated target: information macromolecules
database_cross_reference: ChEBI

nucleic acid
type: Class
subclass of: polynucleotide
subclass of: Restriction
  on property: has part
  some values from: canonical nucleoside residue
subclass of: Restriction
  on property: has part
  some values from: canonical nucleotide residue
definition: A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.
has_exact_synonym: nucleic acids
has OBO namespace: chebi_ontology
has related synonym: NA
has related synonym: Nukleinsaeure
has related synonym: Nukleinsaeuren
has related synonym: acide nucleique
has related synonym: acides nucleiques
has related synonym: acido nucleico
has related synonym: acidos nucleicos
id: CHEBI:33696
in subset: 3 STAR

Axiom
annotated source: nucleic acid
annotated property: has_exact_synonym
annotated target: nucleic acids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: nucleic acid
annotated property: hasRelatedSynonym
annotated target: NA
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: hasRelatedSynonym
annotated target: Nukleinsaeure
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: hasRelatedSynonym
annotated target: Nukleinsaeuren
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: hasRelatedSynonym
annotated target: acide nucleique
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: hasRelatedSynonym
annotated target: acides nucleiques
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: hasRelatedSynonym
annotated target: acido nucleico
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: hasRelatedSynonym
annotated target: acidos nucleicos
database_cross_reference: ChEBI

ribonucleic acid
type: Class
subclass of: nucleic acid
subclass of: Restriction
  on property: has part
  some values from: canonical ribonucleoside residue
subclass of: Restriction
  on property: has part
  some values from: canonical ribonucleotide residue
definition: High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.
database_cross_reference: CAS:63231-63-0
has_exact_synonym: ribonucleic acid
has_exact_synonym: ribonucleic acids
has OBO namespace: chebi_ontology
has related synonym: RNA
has related synonym: RNS
has related synonym: Ribonukleinsaeure
has related synonym: pentosenucleic acids
has related synonym: ribonucleic acids
has related synonym: ribose nucleic acid
has related synonym: yeast nucleic acid
id: CHEBI:33697
in subset: 3 STAR

Axiom
annotated source: ribonucleic acid
annotated property: database_cross_reference
annotated target: CAS:63231-63-0
source: ChemIDplus

Axiom
annotated source: ribonucleic acid
annotated property: has_exact_synonym
annotated target: ribonucleic acid
database_cross_reference: IUPAC

Axiom
annotated source: ribonucleic acid
annotated property: has_exact_synonym
annotated target: ribonucleic acids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: RNA
database_cross_reference: IUPAC

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: RNA
database_cross_reference: UniProt

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: RNS
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: Ribonukleinsaeure
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: pentosenucleic acids
database_cross_reference: ChemIDplus

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: ribonucleic acids
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: ribose nucleic acid
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: hasRelatedSynonym
annotated target: yeast nucleic acid
database_cross_reference: ChEBI

proteinogenic amino-acid residue
type: Class
subclass of: alpha-amino-acid residue
has OBO namespace: chebi_ontology
has related synonym: canonical amino-acid residue
has related synonym: canonical amino-acid residues
has related synonym: common amino acid residues
has related synonym: proteinogenic amino-acid residues
has related synonym: standard amino acid residues
has related synonym: standard amino-acid residues
id: CHEBI:33700
in subset: 3 STAR

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: canonical amino-acid residue
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: canonical amino-acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: common amino acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: proteinogenic amino-acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: standard amino acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: standard amino-acid residues
database_cross_reference: ChEBI

polyatomic cation
type: Class
subclass of: polyatomic ion
subclass of: cation
definition: A cation consisting of more than one atom.
has OBO namespace: chebi_ontology
has related synonym: polyatomic cations
id: CHEBI:33702
in subset: 3 STAR

Axiom
annotated source: polyatomic cation
annotated property: hasRelatedSynonym
annotated target: polyatomic cations
database_cross_reference: ChEBI

amino-acid cation
type: Class
subclass of: organic cation
subclass of: polyatomic cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: amino acid
has OBO namespace: chebi_ontology
has related synonym: amino acid cation
has related synonym: amino acid cations
has related synonym: amino-acid cations
id: CHEBI:33703
in subset: 3 STAR

Axiom
annotated source: amino-acid cation
annotated property: hasRelatedSynonym
annotated target: amino acid cation
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid cation
annotated property: hasRelatedSynonym
annotated target: amino acid cations
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid cation
annotated property: hasRelatedSynonym
annotated target: amino-acid cations
database_cross_reference: ChEBI

alpha-amino acid
type: Class
subclass of: amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: alpha-amino-acid cation
subclass of: Restriction
  on property: is tautomer of
  some values from: alpha-amino-acid zwitterion
definition: An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group.
has alternative id: CHEBI:10208
has alternative id: CHEBI:13779
has alternative id: CHEBI:22442
has alternative id: CHEBI:2642
database_cross_reference: KEGG:C00045
database_cross_reference: KEGG:C05167
has_exact_synonym: alpha-amino acid
has OBO namespace: chebi_ontology
has related synonym: Amino acid
has related synonym: Amino acids
has related synonym: alpha-amino acids
has related synonym: alpha-amino carboxylic acids
id: CHEBI:33704
in subset: 3 STAR

Axiom
annotated source: alpha-amino acid
annotated property: has_exact_synonym
annotated target: alpha-amino acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: alpha-amino acid
annotated property: hasRelatedSynonym
annotated target: Amino acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: alpha-amino acid
annotated property: hasRelatedSynonym
annotated target: Amino acids
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: alpha-amino acid
annotated property: hasRelatedSynonym
annotated target: alpha-amino acids
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino acid
annotated property: hasRelatedSynonym
annotated target: alpha-amino acids
database_cross_reference: JCBN

Axiom
annotated source: alpha-amino acid
annotated property: hasRelatedSynonym
annotated target: alpha-amino carboxylic acids
database_cross_reference: IUPAC

amino-acid residue
type: Class
subclass of: organic group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: anionic amino-acid residue
subclass of: Restriction
  on property: is conjugate base of
  some values from: cationic amino-acid residue
subclass of: Restriction
  on property: is substituent group from
  some values from: amino acid
definition: When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.
has_exact_synonym: amino-acid residue
has OBO namespace: chebi_ontology
has related synonym: amino acid residue
has related synonym: amino acid residues
has related synonym: amino-acid residues
id: CHEBI:33708
in subset: 3 STAR

Axiom
annotated source: amino-acid residue
annotated property: has_exact_synonym
annotated target: amino-acid residue
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino acid residue
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino acid residues
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino-acid residues
database_cross_reference: JCBN

amino acid
type: Class
subclass of: carboxylic acid
subclass of: organic amino compound
subclass of: Restriction
  on property: is conjugate acid of
  some values from: amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: amino-acid cation
definition: A carboxylic acid containing one or more amino groups.
has alternative id: CHEBI:13815
has alternative id: CHEBI:22477
database_cross_reference: Wikipedia:Amino_acid
has OBO namespace: chebi_ontology
has related synonym: Aminocarbonsaeure
has related synonym: Aminokarbonsaeure
has related synonym: Aminosaeure
has related synonym: amino acids
id: CHEBI:33709
in subset: 3 STAR

Axiom
annotated source: amino acid
annotated property: hasRelatedSynonym
annotated target: Aminocarbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: amino acid
annotated property: hasRelatedSynonym
annotated target: Aminokarbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: amino acid
annotated property: hasRelatedSynonym
annotated target: Aminosaeure
database_cross_reference: ChEBI

Axiom
annotated source: amino acid
annotated property: hasRelatedSynonym
annotated target: amino acids
database_cross_reference: ChEBI

alpha-amino-acid residue
type: Class
subclass of: amino-acid residue
subclass of: Restriction
  on property: is substituent group from
  some values from: alpha-amino acid
definition: An amino-acid residue derived from an alpha-amino acid.
has OBO namespace: chebi_ontology
has related synonym: alpha-amino-acid residues
has related synonym: an alpha-amino acid residue
id: CHEBI:33710
in subset: 3 STAR

Axiom
annotated source: alpha-amino-acid residue
annotated property: hasRelatedSynonym
annotated target: alpha-amino-acid residues
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid residue
annotated property: hasRelatedSynonym
annotated target: an alpha-amino acid residue
database_cross_reference: UniProt

alpha-amino-acid cation
type: Class
subclass of: amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alpha-amino acid
has OBO namespace: chebi_ontology
has related synonym: alpha-amino acid cation
has related synonym: alpha-amino acid cations
has related synonym: alpha-amino-acid cations
id: CHEBI:33719
in subset: 3 STAR

Axiom
annotated source: alpha-amino-acid cation
annotated property: hasRelatedSynonym
annotated target: alpha-amino acid cation
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid cation
annotated property: hasRelatedSynonym
annotated target: alpha-amino acid cations
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid cation
annotated property: hasRelatedSynonym
annotated target: alpha-amino-acid cations
database_cross_reference: ChEBI

carbohydrate acid
type: Class
subclass of: carbohydrate
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbohydrate acid anion
has_exact_synonym: carbohydrate acid
has OBO namespace: chebi_ontology
has related synonym: carbohydrate acids
id: CHEBI:33720
in subset: 3 STAR

Axiom
annotated source: carbohydrate acid
annotated property: has_exact_synonym
annotated target: carbohydrate acid
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid
annotated property: hasRelatedSynonym
annotated target: carbohydrate acids
database_cross_reference: ChEBI

carbohydrate acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbohydrate acid
has_exact_synonym: carbohydrate acid anion
has OBO namespace: chebi_ontology
has related synonym: carbohydrate acid anions
id: CHEBI:33721
in subset: 3 STAR

Axiom
annotated source: carbohydrate acid anion
annotated property: has_exact_synonym
annotated target: carbohydrate acid anion
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid anion
annotated property: hasRelatedSynonym
annotated target: carbohydrate acid anions
database_cross_reference: ChEBI

canonical nucleoside residue
type: Class
subclass of: nucleoside residue
has OBO namespace: chebi_ontology
has related synonym: canonical nucleoside residues
has related synonym: common nucleoside residues
has related synonym: nucleoside residue
has related synonym: standard nucleoside residues
id: CHEBI:33791
in subset: 3 STAR

Axiom
annotated source: canonical nucleoside residue
annotated property: hasRelatedSynonym
annotated target: canonical nucleoside residues
database_cross_reference: ChEBI

Axiom
annotated source: canonical nucleoside residue
annotated property: hasRelatedSynonym
annotated target: common nucleoside residues
database_cross_reference: CBN

Axiom
annotated source: canonical nucleoside residue
annotated property: hasRelatedSynonym
annotated target: nucleoside residue
database_cross_reference: CBN

Axiom
annotated source: canonical nucleoside residue
annotated property: hasRelatedSynonym
annotated target: standard nucleoside residues
database_cross_reference: ChEBI

canonical ribonucleoside residue
type: Class
subclass of: canonical nucleoside residue
has OBO namespace: chebi_ontology
has related synonym: N
has related synonym: Nuc
has related synonym: canonical ribonucleoside residues
has related synonym: common ribonucleoside residue
has related synonym: common ribonucleoside residues
has related synonym: standard ribonucleoside residues
id: CHEBI:33792
in subset: 3 STAR

Axiom
annotated source: canonical ribonucleoside residue
annotated property: hasRelatedSynonym
annotated target: N
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: hasRelatedSynonym
annotated target: Nuc
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: hasRelatedSynonym
annotated target: canonical ribonucleoside residues
database_cross_reference: ChEBI

Axiom
annotated source: canonical ribonucleoside residue
annotated property: hasRelatedSynonym
annotated target: common ribonucleoside residue
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: hasRelatedSynonym
annotated target: common ribonucleoside residues
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: hasRelatedSynonym
annotated target: standard ribonucleoside residues
database_cross_reference: ChEBI

organic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: organic molecular entity
definition: An organic compound having at least one hydroxy group attached to a carbon atom.
has alternative id: CHEBI:64710
has_exact_synonym: hydroxy compounds
has OBO namespace: chebi_ontology
has related synonym: organic alcohol
has related synonym: organic hydroxy compounds
id: CHEBI:33822
in subset: 3 STAR

Axiom
annotated source: organic hydroxy compound
annotated property: has_exact_synonym
annotated target: hydroxy compounds
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: organic hydroxy compound
annotated property: hasRelatedSynonym
annotated target: organic alcohol
database_cross_reference: ChEBI

Axiom
annotated source: organic hydroxy compound
annotated property: hasRelatedSynonym
annotated target: organic hydroxy compounds
database_cross_reference: ChEBI

organic cyclic compound
type: Class
subclass of: cyclic compound
subclass of: organic molecule
definition: Any organic molecule that consists of atoms connected in the form of a ring.
has OBO namespace: chebi_ontology
has related synonym: organic cyclic compounds
id: CHEBI:33832
in subset: 3 STAR

Axiom
annotated source: organic cyclic compound
annotated property: hasRelatedSynonym
annotated target: organic cyclic compounds
database_cross_reference: ChEBI

heteroarene
type: Class
subclass of: organic heterocyclic compound
subclass of: organic aromatic compound
definition: A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2).
has_exact_synonym: heteroarenes
has OBO namespace: chebi_ontology
has related synonym: hetarenes
id: CHEBI:33833
in subset: 3 STAR

Axiom
annotated source: heteroarene
annotated property: has_exact_synonym
annotated target: heteroarenes
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: heteroarene
annotated property: hasRelatedSynonym
annotated target: hetarenes
database_cross_reference: IUPAC

conjugated protein
type: Class
subclass of: protein
definition: Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion.
database_cross_reference: COMe:PRX000001
has_exact_synonym: conjugated proteins
has OBO namespace: chebi_ontology
has related synonym: complex protein
id: CHEBI:33837
in subset: 3 STAR

Axiom
annotated source: conjugated protein
annotated property: has_exact_synonym
annotated target: conjugated proteins
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: conjugated protein
annotated property: hasRelatedSynonym
annotated target: complex protein
database_cross_reference: COMe

macromolecule
type: Class
subclass of: polyatomic entity
definition: A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
database_cross_reference: Wikipedia:Macromolecule
has_exact_synonym: macromolecule
has OBO namespace: chebi_ontology
has related synonym: macromolecules
has related synonym: polymer
has related synonym: polymer molecule
has related synonym: polymers
id: CHEBI:33839
in subset: 3 STAR

Axiom
annotated source: macromolecule
annotated property: has_exact_synonym
annotated target: macromolecule
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: macromolecule
annotated property: hasRelatedSynonym
annotated target: macromolecules
database_cross_reference: ChEBI

Axiom
annotated source: macromolecule
annotated property: hasRelatedSynonym
annotated target: polymer
database_cross_reference: ChEBI

Axiom
annotated source: macromolecule
annotated property: hasRelatedSynonym
annotated target: polymer molecule
database_cross_reference: IUPAC

Axiom
annotated source: macromolecule
annotated property: hasRelatedSynonym
annotated target: polymers
database_cross_reference: ChEBI

phenols
type: Class
subclass of: organic aromatic compound
subclass of: organic hydroxy compound
definition: Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
has alternative id: CHEBI:13664
has alternative id: CHEBI:13825
has alternative id: CHEBI:25969
has alternative id: CHEBI:2857
database_cross_reference: KEGG:C15584
database_cross_reference: MetaCyc:Phenols
database_cross_reference: Wikipedia:Phenols
has_exact_synonym: phenols
has OBO namespace: chebi_ontology
has related synonym: Aryl alcohol
has related synonym: a phenol
has related synonym: arenols
id: CHEBI:33853
in subset: 3 STAR

Axiom
annotated source: phenols
annotated property: has_exact_synonym
annotated target: phenols
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: phenols
annotated property: hasRelatedSynonym
annotated target: Aryl alcohol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phenols
annotated property: hasRelatedSynonym
annotated target: a phenol
database_cross_reference: UniProt

Axiom
annotated source: phenols
annotated property: hasRelatedSynonym
annotated target: arenols
database_cross_reference: IUPAC

reagent
type: Class
subclass of: application
definition: A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
has_exact_synonym: reagent
has OBO namespace: chebi_ontology
has related synonym: reactif
has related synonym: reactivo
has related synonym: reagents
id: CHEBI:33893
in subset: 3 STAR

Axiom
annotated source: reagent
annotated property: has_exact_synonym
annotated target: reagent
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: reagent
annotated property: hasRelatedSynonym
annotated target: reactif
database_cross_reference: IUPAC

Axiom
annotated source: reagent
annotated property: hasRelatedSynonym
annotated target: reactivo
database_cross_reference: IUPAC

Axiom
annotated source: reagent
annotated property: hasRelatedSynonym
annotated target: reagents
database_cross_reference: ChEBI

aldohexose
type: Class
subclass of: aldose
subclass of: hexose
definition: A hexose with a (potential) aldehyde group at one end.
has alternative id: CHEBI:2558
has_exact_synonym: aldohexose
has OBO namespace: chebi_ontology
has related synonym: aldohexoses
id: CHEBI:33917
in subset: 3 STAR

Axiom
annotated source: aldohexose
annotated property: has_exact_synonym
annotated target: aldohexose
database_cross_reference: ChEBI

Axiom
annotated source: aldohexose
annotated property: hasRelatedSynonym
annotated target: aldohexoses
database_cross_reference: ChEBI

macronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
has OBO namespace: chebi_ontology
has related synonym: macronutrients
id: CHEBI:33937
in subset: 3 STAR

Axiom
annotated source: macronutrient
annotated property: hasRelatedSynonym
annotated target: macronutrients
database_cross_reference: ChEBI

serotonin(1+)
type: Class
subclass of: independent continuant
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: serotonin
definition: An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3.
has_exact_synonym: 2-(5-hydroxy-1H-indol-3-yl)ethanaminium
has OBO namespace: chebi_ontology
has related synonym: serotonin
has related synonym: serotonin cation
id: CHEBI:350546
in subset: 3 STAR

Axiom
annotated source: serotonin(1+)
annotated property: has_exact_synonym
annotated target: 2-(5-hydroxy-1H-indol-3-yl)ethanaminium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: serotonin(1+)
annotated property: hasRelatedSynonym
annotated target: serotonin
database_cross_reference: UniProt

Axiom
annotated source: serotonin(1+)
annotated property: hasRelatedSynonym
annotated target: serotonin cation
database_cross_reference: ChEBI

nitrogen hydride
type: Class
subclass of: pnictogen hydride
subclass of: nitrogen molecular entity
has OBO namespace: chebi_ontology
has related synonym: nitrogen hydrides
id: CHEBI:35106
in subset: 3 STAR

Axiom
annotated source: nitrogen hydride
annotated property: hasRelatedSynonym
annotated target: nitrogen hydrides
database_cross_reference: ChEBI

azane
type: Class
subclass of: nitrogen hydride
definition: Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
has OBO namespace: chebi_ontology
has related synonym: azanes
id: CHEBI:35107
in subset: 3 STAR

Axiom
annotated source: azane
annotated property: hasRelatedSynonym
annotated target: azanes
database_cross_reference: ChEBI

inhibitor
type: Class
subclass of: biological role
definition: A substance that diminishes the rate of a chemical reaction.
has_exact_synonym: inhibitor
has OBO namespace: chebi_ontology
has related synonym: inhibidor
has related synonym: inhibiteur
has related synonym: inhibitors
id: CHEBI:35222
in subset: 3 STAR

Axiom
annotated source: inhibitor
annotated property: has_exact_synonym
annotated target: inhibitor
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: inhibitor
annotated property: hasRelatedSynonym
annotated target: inhibidor
database_cross_reference: ChEBI

Axiom
annotated source: inhibitor
annotated property: hasRelatedSynonym
annotated target: inhibiteur
database_cross_reference: ChEBI

Axiom
annotated source: inhibitor
annotated property: hasRelatedSynonym
annotated target: inhibitors
database_cross_reference: ChEBI

catalyst
type: Class
subclass of: chemical role
definition: A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
has_exact_synonym: catalyst
has OBO namespace: chebi_ontology
has related synonym: Katalysator
has related synonym: catalizador
has related synonym: catalyseur
id: CHEBI:35223
in subset: 3 STAR

Axiom
annotated source: catalyst
annotated property: has_exact_synonym
annotated target: catalyst
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: catalyst
annotated property: hasRelatedSynonym
annotated target: Katalysator
database_cross_reference: ChEBI

Axiom
annotated source: catalyst
annotated property: hasRelatedSynonym
annotated target: catalizador
database_cross_reference: ChEBI

Axiom
annotated source: catalyst
annotated property: hasRelatedSynonym
annotated target: catalyseur
database_cross_reference: ChEBI

amino-acid zwitterion
type: Class
subclass of: zwitterion
definition: The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group.
has OBO namespace: chebi_ontology
has related synonym: amino acid zwitterion
has related synonym: amino acid zwitterions
has related synonym: amino-acid zwitterions
id: CHEBI:35238
in subset: 3 STAR

Axiom
annotated source: amino-acid zwitterion
annotated property: hasRelatedSynonym
annotated target: amino acid zwitterion
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid zwitterion
annotated property: hasRelatedSynonym
annotated target: amino acid zwitterions
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid zwitterion
annotated property: hasRelatedSynonym
annotated target: amino-acid zwitterions
database_cross_reference: ChEBI

quaternary ammonium ion
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
definition: A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups.
has alternative id: CHEBI:26470
has alternative id: CHEBI:8693
database_cross_reference: KEGG:C06703
has_exact_synonym: quaternary ammonium ion
has OBO namespace: chebi_ontology
has related synonym: Quaternary amine
has related synonym: a quaternary ammonium
has related synonym: quaternary ammonium ions
id: CHEBI:35267
in subset: 3 STAR

Axiom
annotated source: quaternary ammonium ion
annotated property: has_exact_synonym
annotated target: quaternary ammonium ion
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: quaternary ammonium ion
annotated property: hasRelatedSynonym
annotated target: Quaternary amine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: quaternary ammonium ion
annotated property: hasRelatedSynonym
annotated target: a quaternary ammonium
database_cross_reference: UniProt

Axiom
annotated source: quaternary ammonium ion
annotated property: hasRelatedSynonym
annotated target: quaternary ammonium ions
database_cross_reference: ChEBI

ammonium ion derivative
type: Class
subclass of: polyatomic cation
subclass of: nitrogen molecular entity
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonium
definition: A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc).
has OBO namespace: chebi_ontology
has related synonym: ammonium ion derivatives
has related synonym: azanium ion derivative
has related synonym: azanium ion derivatives
id: CHEBI:35274
in subset: 3 STAR

Axiom
annotated source: ammonium ion derivative
annotated property: hasRelatedSynonym
annotated target: ammonium ion derivatives
database_cross_reference: ChEBI

Axiom
annotated source: ammonium ion derivative
annotated property: hasRelatedSynonym
annotated target: azanium ion derivative
database_cross_reference: ChEBI

Axiom
annotated source: ammonium ion derivative
annotated property: hasRelatedSynonym
annotated target: azanium ion derivatives
database_cross_reference: ChEBI

acylcholine
type: Class
subclass of: quaternary ammonium ion
definition: A choline ester formed from choline and a carboxylic acid.
has alternative id: CHEBI:13245
has alternative id: CHEBI:22227
has alternative id: CHEBI:2463
database_cross_reference: KEGG:C01777
has OBO namespace: chebi_ontology
has related synonym: acylcholines
has related synonym: an acylcholine
id: CHEBI:35287
in subset: 3 STAR

Axiom
annotated source: acylcholine
annotated property: hasRelatedSynonym
annotated target: acylcholines
database_cross_reference: ChEBI

Axiom
annotated source: acylcholine
annotated property: hasRelatedSynonym
annotated target: an acylcholine
database_cross_reference: UniProt

steroid
type: Class
subclass of: lipid
subclass of: organic polycyclic compound
definition: Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.
has alternative id: CHEBI:13687
has alternative id: CHEBI:26768
has alternative id: CHEBI:9263
database_cross_reference: KEGG:C00377
database_cross_reference: MetaCyc:Steroids
has_exact_synonym: Steroid
has_exact_synonym: steroids
has OBO namespace: chebi_ontology
has related synonym: a steroid
id: CHEBI:35341
in subset: 3 STAR

Axiom
annotated source: steroid
annotated property: has_exact_synonym
annotated target: Steroid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: steroid
annotated property: has_exact_synonym
annotated target: steroids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: steroid
annotated property: hasRelatedSynonym
annotated target: a steroid
database_cross_reference: UniProt

hydroxy steroid
type: Class
subclass of: organic hydroxy compound
subclass of: steroid
has alternative id: CHEBI:24748
has alternative id: CHEBI:5814
database_cross_reference: KEGG:C02159
has OBO namespace: chebi_ontology
has related synonym: Hydroxysteroid
has related synonym: hydroxy steroids
has related synonym: hydroxysteroids
id: CHEBI:35350
in subset: 3 STAR

Axiom
annotated source: hydroxy steroid
annotated property: hasRelatedSynonym
annotated target: Hydroxysteroid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydroxy steroid
annotated property: hasRelatedSynonym
annotated target: hydroxy steroids
database_cross_reference: ChEBI

Axiom
annotated source: hydroxy steroid
annotated property: hasRelatedSynonym
annotated target: hydroxysteroids
database_cross_reference: ChEBI

organonitrogen compound
type: Class
subclass of: heteroorganic entity
subclass of: nitrogen molecular entity
definition: Any heteroorganic entity containing at least one carbon-nitrogen bond.
has_exact_synonym: organonitrogen compounds
has OBO namespace: chebi_ontology
has related synonym: organonitrogens
id: CHEBI:35352
in subset: 3 STAR

Axiom
annotated source: organonitrogen compound
annotated property: has_exact_synonym
annotated target: organonitrogen compounds
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: organonitrogen compound
annotated property: hasRelatedSynonym
annotated target: organonitrogens
database_cross_reference: ChEBI

monosaccharide
type: Class
subclass of: carbohydrate
definition: Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group.
has alternative id: CHEBI:25407
has alternative id: CHEBI:6984
database_cross_reference: KEGG:C06698
has_exact_synonym: Monosaccharide
has_exact_synonym: monosaccharides
has OBO namespace: chebi_ontology
has related synonym: Monosaccharid
has related synonym: Monosacharid
has related synonym: monosacarido
has related synonym: monosacaridos
id: CHEBI:35381
in subset: 3 STAR

Axiom
annotated source: monosaccharide
annotated property: has_exact_synonym
annotated target: Monosaccharide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: monosaccharide
annotated property: has_exact_synonym
annotated target: monosaccharides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: monosaccharide
annotated property: hasRelatedSynonym
annotated target: Monosaccharid
database_cross_reference: ChEBI

Axiom
annotated source: monosaccharide
annotated property: hasRelatedSynonym
annotated target: Monosacharid
database_cross_reference: ChEBI

Axiom
annotated source: monosaccharide
annotated property: hasRelatedSynonym
annotated target: monosacarido
database_cross_reference: ChEBI

Axiom
annotated source: monosaccharide
annotated property: hasRelatedSynonym
annotated target: monosacaridos
database_cross_reference: IUPAC

oxoanion
type: Class
subclass of: oxide
subclass of: polyatomic anion
definition: An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.
has alternative id: CHEBI:33274
has alternative id: CHEBI:33436
has_exact_synonym: oxoanion
has OBO namespace: chebi_ontology
has related synonym: oxoacid anions
has related synonym: oxoanions
id: CHEBI:35406
in subset: 3 STAR

Axiom
annotated source: oxoanion
annotated property: has_exact_synonym
annotated target: oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: oxoanion
annotated property: hasRelatedSynonym
annotated target: oxoacid anions
database_cross_reference: ChEBI

Axiom
annotated source: oxoanion
annotated property: hasRelatedSynonym
annotated target: oxoanions
database_cross_reference: ChEBI

anti-inflammatory drug
type: Class
subclass of: drug
subclass of: anti-inflammatory agent
definition: A substance that reduces or suppresses inflammation.
has OBO namespace: chebi_ontology
has related synonym: anti-inflammatory drugs
has related synonym: antiinflammatory agent
has related synonym: antiinflammatory drug
has related synonym: antiinflammatory drugs
id: CHEBI:35472
in subset: 3 STAR

Axiom
annotated source: anti-inflammatory drug
annotated property: hasRelatedSynonym
annotated target: anti-inflammatory drugs
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory drug
annotated property: hasRelatedSynonym
annotated target: antiinflammatory agent
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory drug
annotated property: hasRelatedSynonym
annotated target: antiinflammatory drug
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory drug
annotated property: hasRelatedSynonym
annotated target: antiinflammatory drugs
database_cross_reference: ChEBI

alkali metal salt
type: Class
subclass of: salt
subclass of: alkali metal molecular entity
has OBO namespace: chebi_ontology
has related synonym: alkali metal salts
id: CHEBI:35479
in subset: 3 STAR

Axiom
annotated source: alkali metal salt
annotated property: hasRelatedSynonym
annotated target: alkali metal salts
database_cross_reference: ChEBI

natural product fundamental parent
type: Class
subclass of: organic fundamental parent
has_exact_synonym: natural product fundamental parents
has OBO namespace: chebi_ontology
id: CHEBI:35507
in subset: 3 STAR

Axiom
annotated source: natural product fundamental parent
annotated property: has_exact_synonym
annotated target: natural product fundamental parents
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

steroid fundamental parent
type: Class
subclass of: steroid
subclass of: natural product fundamental parent
has OBO namespace: chebi_ontology
has related synonym: steroid fundamental parents
id: CHEBI:35508
in subset: 3 STAR

Axiom
annotated source: steroid fundamental parent
annotated property: hasRelatedSynonym
annotated target: steroid fundamental parents
database_cross_reference: ChEBI

cholane
type: Class
subclass of: steroid fundamental parent
has_exact_synonym: cholane
has OBO namespace: chebi_ontology
id: CHEBI:35519
in subset: 3 STAR

Axiom
annotated source: cholane
annotated property: has_exact_synonym
annotated target: cholane
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

sympathomimetic agent
type: Class
subclass of: adrenergic agent
definition: A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
has OBO namespace: chebi_ontology
has related synonym: sympathomimetic
has related synonym: sympathomimetics
id: CHEBI:35524
in subset: 3 STAR

Axiom
annotated source: sympathomimetic agent
annotated property: hasRelatedSynonym
annotated target: sympathomimetic
database_cross_reference: ChEBI

Axiom
annotated source: sympathomimetic agent
annotated property: hasRelatedSynonym
annotated target: sympathomimetics
database_cross_reference: ChEBI

cardiovascular drug
type: Class
subclass of: drug
definition: A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
has OBO namespace: chebi_ontology
has related synonym: cardiovascular agent
has related synonym: cardiovascular drugs
id: CHEBI:35554
in subset: 3 STAR

Axiom
annotated source: cardiovascular drug
annotated property: hasRelatedSynonym
annotated target: cardiovascular agent
database_cross_reference: ChEBI

Axiom
annotated source: cardiovascular drug
annotated property: hasRelatedSynonym
annotated target: cardiovascular drugs
database_cross_reference: ChEBI

alpha-adrenergic agonist
type: Class
subclass of: adrenergic agonist
subclass of: alpha-adrenergic drug
definition: An agent that selectively binds to and activates alpha-adrenergic receptors.
has OBO namespace: chebi_ontology
has related synonym: alpha-adrenergic agonists
has related synonym: alpha-adrenergic receptor agonist
has related synonym: alpha-adrenoceptor agonists
id: CHEBI:35569
in subset: 3 STAR

Axiom
annotated source: alpha-adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: alpha-adrenergic agonists
database_cross_reference: ChEBI

Axiom
annotated source: alpha-adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: alpha-adrenergic receptor agonist
database_cross_reference: ChEBI

Axiom
annotated source: alpha-adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: alpha-adrenoceptor agonists
database_cross_reference: IUPHAR

carbon oxoanion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: organooxygen compound
definition: A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.
has_exact_synonym: carbon oxoanion
has OBO namespace: chebi_ontology
has related synonym: carbon oxoanions
has related synonym: oxocarbon anion
has related synonym: oxocarbon anions
id: CHEBI:35604
in subset: 3 STAR

Axiom
annotated source: carbon oxoanion
annotated property: has_exact_synonym
annotated target: carbon oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoanion
annotated property: hasRelatedSynonym
annotated target: carbon oxoanions
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoanion
annotated property: hasRelatedSynonym
annotated target: oxocarbon anion
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoanion
annotated property: hasRelatedSynonym
annotated target: oxocarbon anions
database_cross_reference: ChEBI

carbon oxoacid
type: Class
subclass of: oxoacid
subclass of: organooxygen compound
has OBO namespace: chebi_ontology
has related synonym: carbon oxoacids
has related synonym: oxoacids of carbon
id: CHEBI:35605
in subset: 3 STAR

Axiom
annotated source: carbon oxoacid
annotated property: hasRelatedSynonym
annotated target: carbon oxoacids
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoacid
annotated property: hasRelatedSynonym
annotated target: oxoacids of carbon
database_cross_reference: ChEBI

vasodilator agent
type: Class
subclass of: cardiovascular drug
definition: A drug used to cause dilation of the blood vessels.
has OBO namespace: chebi_ontology
has related synonym: vasodilator
has related synonym: vasodilator agents
id: CHEBI:35620
in subset: 3 STAR

Axiom
annotated source: vasodilator agent
annotated property: hasRelatedSynonym
annotated target: vasodilator
database_cross_reference: ChEBI

Axiom
annotated source: vasodilator agent
annotated property: hasRelatedSynonym
annotated target: vasodilator agents
database_cross_reference: ChEBI

dicarboxylic acid
type: Class
subclass of: dicarboxylic acids and O-substituted derivatives
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dicarboxylic acid anion
definition: Any carboxylic acid containing two carboxy groups.
has alternative id: CHEBI:23692
has alternative id: CHEBI:36172
has alternative id: CHEBI:4501
database_cross_reference: KEGG:C02028
has_exact_synonym: Dicarboxylic acid
has OBO namespace: chebi_ontology
has related synonym: dicarboxylic acids
id: CHEBI:35692
in subset: 3 STAR

Axiom
annotated source: dicarboxylic acid
annotated property: has_exact_synonym
annotated target: Dicarboxylic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: dicarboxylic acid
annotated property: hasRelatedSynonym
annotated target: dicarboxylic acids
database_cross_reference: ChEBI

dicarboxylic acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: dicarboxylic acid
has_exact_synonym: dicarboxylic acid anion
has OBO namespace: chebi_ontology
has related synonym: dicarboxylic acid anions
id: CHEBI:35693
in subset: 3 STAR

Axiom
annotated source: dicarboxylic acid anion
annotated property: has_exact_synonym
annotated target: dicarboxylic acid anion
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: dicarboxylic acid anions
database_cross_reference: ChEBI

ester
type: Class
subclass of: organooxygen compound
definition: A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter.
has alternative id: CHEBI:23960
has alternative id: CHEBI:4859
database_cross_reference: KEGG:C00287
database_cross_reference: Wikipedia:Ester
has_exact_synonym: Ester
has OBO namespace: chebi_ontology
has related synonym: esters
id: CHEBI:35701
in subset: 3 STAR

Axiom
annotated source: ester
annotated property: has_exact_synonym
annotated target: Ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ester
annotated property: hasRelatedSynonym
annotated target: esters
database_cross_reference: ChEBI

sulfated glycosaminoglycan
type: Class
subclass of: glycosaminoglycan
subclass of: carbohydrate sulfate
has OBO namespace: chebi_ontology
has related synonym: glycosaminoglycan sulfate
has related synonym: glycosaminoglycan sulfates
has related synonym: sulfated glycosaminoglycans
id: CHEBI:35722
in subset: 3 STAR

Axiom
annotated source: sulfated glycosaminoglycan
annotated property: hasRelatedSynonym
annotated target: glycosaminoglycan sulfate
database_cross_reference: ChEBI

Axiom
annotated source: sulfated glycosaminoglycan
annotated property: hasRelatedSynonym
annotated target: glycosaminoglycan sulfates
database_cross_reference: ChEBI

Axiom
annotated source: sulfated glycosaminoglycan
annotated property: hasRelatedSynonym
annotated target: sulfated glycosaminoglycans
database_cross_reference: ChEBI

carbohydrate sulfate
type: Class
subclass of: organic sulfate
subclass of: sulfuric ester
subclass of: carbohydrate derivative
has OBO namespace: chebi_ontology
has related synonym: carbohydrate sulfates
has related synonym: carbohydrate sulphates
id: CHEBI:35724
in subset: 3 STAR

Axiom
annotated source: carbohydrate sulfate
annotated property: hasRelatedSynonym
annotated target: carbohydrate sulfates
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate sulfate
annotated property: hasRelatedSynonym
annotated target: carbohydrate sulphates
database_cross_reference: ChEBI

monocarboxylic acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: monocarboxylic acid
definition: A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.
has alternative id: CHEBI:13657
has alternative id: CHEBI:25382
has alternative id: CHEBI:3407
database_cross_reference: KEGG:C00060
has OBO namespace: chebi_ontology
has related synonym: Carboxylate
has related synonym: Monocarboxylate
has related synonym: a monocarboxylate
has related synonym: monocarboxylates
has related synonym: monocarboxylic acid anions
id: CHEBI:35757
in subset: 3 STAR

Axiom
annotated source: monocarboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: Carboxylate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: monocarboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: Monocarboxylate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: monocarboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: a monocarboxylate
database_cross_reference: UniProt

Axiom
annotated source: monocarboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: monocarboxylates
database_cross_reference: ChEBI

Axiom
annotated source: monocarboxylic acid anion
annotated property: hasRelatedSynonym
annotated target: monocarboxylic acid anions
database_cross_reference: ChEBI

pnictogen hydride
type: Class
subclass of: inorganic hydride
subclass of: pnictogen molecular entity
has_exact_synonym: pnictogen hydride
has OBO namespace: chebi_ontology
has related synonym: pnictogen hydrides
id: CHEBI:35881
in subset: 3 STAR

Axiom
annotated source: pnictogen hydride
annotated property: has_exact_synonym
annotated target: pnictogen hydride
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen hydride
annotated property: hasRelatedSynonym
annotated target: pnictogen hydrides
database_cross_reference: ChEBI

neurotransmitter agent
type: Class
subclass of: drug
subclass of: pharmacological role
definition: A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
has OBO namespace: chebi_ontology
has related synonym: neurotransmitter agents
id: CHEBI:35942
in subset: 3 STAR

Axiom
annotated source: neurotransmitter agent
annotated property: hasRelatedSynonym
annotated target: neurotransmitter agents
database_cross_reference: ChEBI

cholanoid
type: Class
subclass of: steroid
subclass of: Restriction
  on property: has parent hydride
  some values from: cholane
has alternative id: CHEBI:22867
has alternative id: CHEBI:50419
database_cross_reference: LIPID_MAPS_class:LMST04
has OBO namespace: chebi_ontology
has related synonym: bile acids and derivatives
has related synonym: cholanoids
id: CHEBI:36078
in subset: 3 STAR

Axiom
annotated source: cholanoid
annotated property: database_cross_reference
annotated target: LIPID_MAPS_class:LMST04
source: LIPID MAPS

Axiom
annotated source: cholanoid
annotated property: hasRelatedSynonym
annotated target: bile acids and derivatives
database_cross_reference: LIPID_MAPS

Axiom
annotated source: cholanoid
annotated property: hasRelatedSynonym
annotated target: cholanoids
database_cross_reference: ChEBI

protein
type: Class
subclass of: information biomacromolecule
subclass of: Restriction
  on property: has part
  some values from: protein polypeptide chain
definition: A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome.
has alternative id: CHEBI:13677
has alternative id: CHEBI:14911
has_exact_synonym: proteins
has OBO namespace: chebi_ontology
id: CHEBI:36080
in subset: 3 STAR

Axiom
annotated source: protein
annotated property: has_exact_synonym
annotated target: proteins
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

bile acid anion
type: Class
subclass of: monocarboxylic acid anion
subclass of: steroid acid anion
has OBO namespace: chebi_ontology
has related synonym: bile acid anions
id: CHEBI:36235
in subset: 3 STAR

Axiom
annotated source: bile acid anion
annotated property: hasRelatedSynonym
annotated target: bile acid anions
database_cross_reference: ChEBI

cholanic acid
type: Class
subclass of: cholanic acids
definition: A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24.
database_cross_reference: CAS:25312-65-6
database_cross_reference: Patent:JP2008069152
database_cross_reference: Reaxys:13246008
has_exact_synonym: cholan-24-oic acid
has OBO namespace: chebi_ontology
id: CHEBI:36237
in subset: 3 STAR

Axiom
annotated source: cholanic acid
annotated property: database_cross_reference
annotated target: CAS:25312-65-6
source: ChemIDplus

Axiom
annotated source: cholanic acid
annotated property: database_cross_reference
annotated target: Reaxys:13246008
source: Reaxys

Axiom
annotated source: cholanic acid
annotated property: has_exact_synonym
annotated target: cholan-24-oic acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

5beta-cholanic acid
type: Class
subclass of: cholanic acid
subclass of: 5beta-cholanic acids
database_cross_reference: Beilstein:3214794
database_cross_reference: CAS:546-18-9
database_cross_reference: LIPID_MAPS_instance:LMST04010441
has_exact_synonym: 5beta-cholan-24-oic acid
has_exact_synonym: 5beta-cholanic acid
has OBO namespace: chebi_ontology
has related synonym: (5beta)-cholan-24-oic acid
has related synonym: (5beta,17beta)-gamma-methylandrostane-17-butanoic acid
has related synonym: 5beta-cholanoic acid
has related synonym: ursocholanic acid
id: CHEBI:36238
in subset: 3 STAR

Axiom
annotated source: 5beta-cholanic acid
annotated property: database_cross_reference
annotated target: Beilstein:3214794
source: Beilstein

Axiom
annotated source: 5beta-cholanic acid
annotated property: database_cross_reference
annotated target: CAS:546-18-9
source: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: database_cross_reference
annotated target: LIPID_MAPS_instance:LMST04010441
source: LIPID MAPS

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_exact_synonym
annotated target: 5beta-cholan-24-oic acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_exact_synonym
annotated target: 5beta-cholanic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: hasRelatedSynonym
annotated target: (5beta)-cholan-24-oic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: hasRelatedSynonym
annotated target: (5beta,17beta)-gamma-methylandrostane-17-butanoic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: hasRelatedSynonym
annotated target: 5beta-cholanoic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: hasRelatedSynonym
annotated target: ursocholanic acid
database_cross_reference: ChemIDplus

5beta-cholanic acids
type: Class
subclass of: 5beta steroid
subclass of: cholanic acids
subclass of: Restriction
  on property: has parent hydride
  some values from: 5beta-cholane
definition: Members of the class of cholanic acids based on a 5beta-cholane skeleton.
has OBO namespace: chebi_ontology
id: CHEBI:36248
in subset: 3 STAR

bile acid salt
type: Class
subclass of: organic salt
subclass of: cholanoid
definition: A salt of a bile acid.
has OBO namespace: chebi_ontology
has related synonym: bile acid salts
id: CHEBI:36277
in subset: 3 STAR

Axiom
annotated source: bile acid salt
annotated property: hasRelatedSynonym
annotated target: bile acid salts
database_cross_reference: ChEBI

cholanic acids
type: Class
subclass of: cholanoid
subclass of: steroid acid
has alternative id: CHEBI:23166
has alternative id: CHEBI:23211
has OBO namespace: chebi_ontology
id: CHEBI:36278
in subset: 1 STAR

lepton
type: Class
subclass of: fundamental particle
subclass of: fermion
definition: Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin).
has OBO namespace: chebi_ontology
has related synonym: leptons
id: CHEBI:36338
in subset: 3 STAR

Axiom
annotated source: lepton
annotated property: hasRelatedSynonym
annotated target: leptons
database_cross_reference: ChEBI

baryon
type: Class
subclass of: fermion
subclass of: hadron
definition: Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy).
has OBO namespace: chebi_ontology
has related synonym: baryons
id: CHEBI:36339
in subset: 3 STAR

Axiom
annotated source: baryon
annotated property: hasRelatedSynonym
annotated target: baryons
database_cross_reference: ChEBI

fermion
type: Class
subclass of: subatomic particle
definition: Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi.
has_exact_synonym: fermion
has OBO namespace: chebi_ontology
has related synonym: fermions
id: CHEBI:36340
in subset: 3 STAR

Axiom
annotated source: fermion
annotated property: has_exact_synonym
annotated target: fermion
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: fermion
annotated property: hasRelatedSynonym
annotated target: fermions
database_cross_reference: ChEBI

boson
type: Class
subclass of: subatomic particle
definition: Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose.
has_exact_synonym: boson
has OBO namespace: chebi_ontology
has related synonym: bosons
id: CHEBI:36341
in subset: 3 STAR

Axiom
annotated source: boson
annotated property: has_exact_synonym
annotated target: boson
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: boson
annotated property: hasRelatedSynonym
annotated target: bosons
database_cross_reference: ChEBI

subatomic particle
type: Class
definition: A particle smaller than an atom.
database_cross_reference: Wikipedia:Subatomic_particle
has OBO namespace: chebi_ontology
has related synonym: subatomic particles
id: CHEBI:36342
in subset: 3 STAR

Axiom
annotated source: subatomic particle
annotated property: hasRelatedSynonym
annotated target: subatomic particles
database_cross_reference: ChEBI

composite particle
type: Class
subclass of: subatomic particle
definition: A subatomic particle known to have substructure (i.e. consisting of smaller particles).
has OBO namespace: chebi_ontology
has related synonym: composite particles
id: CHEBI:36343
in subset: 3 STAR

Axiom
annotated source: composite particle
annotated property: hasRelatedSynonym
annotated target: composite particles
database_cross_reference: ChEBI

hadron
type: Class
subclass of: composite particle
definition: Hadron is a subatomic particle which experiences the strong force.
has OBO namespace: chebi_ontology
has related synonym: hadrons
id: CHEBI:36344
in subset: 3 STAR

Axiom
annotated source: hadron
annotated property: hasRelatedSynonym
annotated target: hadrons
database_cross_reference: ChEBI

nuclear particle
type: Class
subclass of: subatomic particle
definition: A nucleus or any of its constituents in any of their energy states.
has_exact_synonym: nuclear particle
has OBO namespace: chebi_ontology
id: CHEBI:36347
in subset: 3 STAR

Axiom
annotated source: nuclear particle
annotated property: has_exact_synonym
annotated target: nuclear particle
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

polyatomic entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: group
definition: Any molecular entity consisting of more than one atom.
has OBO namespace: chebi_ontology
has related synonym: polyatomic entities
id: CHEBI:36357
in subset: 3 STAR

Axiom
annotated source: polyatomic entity
annotated property: hasRelatedSynonym
annotated target: polyatomic entities
database_cross_reference: ChEBI

polyatomic ion
type: Class
subclass of: ion
subclass of: polyatomic entity
definition: An ion consisting of more than one atom.
has OBO namespace: chebi_ontology
has related synonym: polyatomic ions
id: CHEBI:36358
in subset: 3 STAR

Axiom
annotated source: polyatomic ion
annotated property: hasRelatedSynonym
annotated target: polyatomic ions
database_cross_reference: ChEBI

carbonyl compound
type: Class
subclass of: organic oxo compound
subclass of: organooxygen compound
subclass of: Restriction
  on property: has part
  some values from: carbonyl group
definition: Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.
has_exact_synonym: carbonyl compounds
has OBO namespace: chebi_ontology
id: CHEBI:36586
in subset: 3 STAR

Axiom
annotated source: carbonyl compound
annotated property: has_exact_synonym
annotated target: carbonyl compounds
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

organic oxo compound
type: Class
subclass of: organic molecule
subclass of: Restriction
  on property: has part
  some values from: oxo group
definition: Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element.
has_exact_synonym: oxo compounds
has OBO namespace: chebi_ontology
has related synonym: organic oxo compounds
id: CHEBI:36587
in subset: 3 STAR

Axiom
annotated source: organic oxo compound
annotated property: has_exact_synonym
annotated target: oxo compounds
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: organic oxo compound
annotated property: hasRelatedSynonym
annotated target: organic oxo compounds
database_cross_reference: ChEBI

biladienes
type: Class
subclass of: linear tetrapyrrole
definition: Compounds based on a biladiene skeleton.
has OBO namespace: chebi_ontology
id: CHEBI:36735
in subset: 3 STAR

chalcogen hydride
type: Class
subclass of: inorganic hydride
subclass of: chalcogen molecular entity
has_exact_synonym: chalcogen hydride
has OBO namespace: chebi_ontology
has related synonym: chalcogen hydrides
id: CHEBI:36902
in subset: 3 STAR

Axiom
annotated source: chalcogen hydride
annotated property: has_exact_synonym
annotated target: chalcogen hydride
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen hydride
annotated property: hasRelatedSynonym
annotated target: chalcogen hydrides
database_cross_reference: ChEBI

inorganic ion
type: Class
subclass of: inorganic molecular entity
subclass of: ion
has OBO namespace: chebi_ontology
has related synonym: inorganic ions
id: CHEBI:36914
in subset: 3 STAR

Axiom
annotated source: inorganic ion
annotated property: hasRelatedSynonym
annotated target: inorganic ions
database_cross_reference: ChEBI

inorganic cation
type: Class
subclass of: inorganic ion
subclass of: cation
has OBO namespace: chebi_ontology
has related synonym: inorganic cations
id: CHEBI:36915
in subset: 3 STAR

Axiom
annotated source: inorganic cation
annotated property: hasRelatedSynonym
annotated target: inorganic cations
database_cross_reference: ChEBI

cation
type: Class
subclass of: ion
definition: A monoatomic or polyatomic species having one or more elementary charges of the proton.
has alternative id: CHEBI:23058
has alternative id: CHEBI:3473
database_cross_reference: KEGG:C01373
has_exact_synonym: Cation
has_exact_synonym: cation
has OBO namespace: chebi_ontology
has related synonym: Kation
has related synonym: Kationen
has related synonym: cationes
has related synonym: cations
id: CHEBI:36916
in subset: 3 STAR

Axiom
annotated source: cation
annotated property: has_exact_synonym
annotated target: Cation
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: cation
annotated property: has_exact_synonym
annotated target: cation
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: has_exact_synonym
annotated target: cation
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: cation
annotated property: hasRelatedSynonym
annotated target: Kation
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: hasRelatedSynonym
annotated target: Kationen
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: hasRelatedSynonym
annotated target: cationes
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: hasRelatedSynonym
annotated target: cations
database_cross_reference: ChEBI

chalcocarbonic acid
type: Class
subclass of: organochalcogen compound
has_exact_synonym: chalcocarbonic acid
has_exact_synonym: chalcocarbonic acids
has OBO namespace: chebi_ontology
has related synonym: chalcocarbonic acids
id: CHEBI:36961
in subset: 3 STAR

Axiom
annotated source: chalcocarbonic acid
annotated property: has_exact_synonym
annotated target: chalcocarbonic acid
database_cross_reference: ChEBI

Axiom
annotated source: chalcocarbonic acid
annotated property: has_exact_synonym
annotated target: chalcocarbonic acids
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: chalcocarbonic acid
annotated property: hasRelatedSynonym
annotated target: chalcocarbonic acids
database_cross_reference: ChEBI

organochalcogen compound
type: Class
subclass of: heteroorganic entity
subclass of: chalcogen molecular entity
definition: An organochalcogen compound is a compound containing at least one carbon-chalcogen bond.
has_exact_synonym: organochalcogen compound
has OBO namespace: chebi_ontology
has related synonym: organochalcogen compounds
id: CHEBI:36962
in subset: 3 STAR

Axiom
annotated source: organochalcogen compound
annotated property: has_exact_synonym
annotated target: organochalcogen compound
database_cross_reference: ChEBI

Axiom
annotated source: organochalcogen compound
annotated property: hasRelatedSynonym
annotated target: organochalcogen compounds
database_cross_reference: ChEBI

organooxygen compound
type: Class
subclass of: oxygen molecular entity
subclass of: organochalcogen compound
definition: An organochalcogen compound containing at least one carbon-oxygen bond.
database_cross_reference: PMID:17586126
has_exact_synonym: organooxygen compound
has OBO namespace: chebi_ontology
has related synonym: organooxygen compounds
id: CHEBI:36963
in subset: 3 STAR

Axiom
annotated source: organooxygen compound
annotated property: database_cross_reference
annotated target: PMID:17586126
source: Europe PMC

Axiom
annotated source: organooxygen compound
annotated property: has_exact_synonym
annotated target: organooxygen compound
database_cross_reference: ChEBI

Axiom
annotated source: organooxygen compound
annotated property: hasRelatedSynonym
annotated target: organooxygen compounds
database_cross_reference: ChEBI

amino-acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: organonitrogen compound
subclass of: Restriction
  on property: is conjugate base of
  some values from: amino acid
has OBO namespace: chebi_ontology
has related synonym: amino acid anion
has related synonym: amino acid anions
has related synonym: amino-acid anions
id: CHEBI:37022
in subset: 3 STAR

Axiom
annotated source: amino-acid anion
annotated property: hasRelatedSynonym
annotated target: amino acid anion
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid anion
annotated property: hasRelatedSynonym
annotated target: amino acid anions
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid anion
annotated property: hasRelatedSynonym
annotated target: amino-acid anions
database_cross_reference: ChEBI

glucan
type: Class
subclass of: homopolysaccharide
definition: A polysaccharide composed of glucose residues.
has alternative id: CHEBI:24255
has alternative id: CHEBI:5392
database_cross_reference: CAS:9037-91-6
database_cross_reference: KEGG:C01379
has_exact_synonym: Glucan
has_exact_synonym: glucan
has OBO namespace: chebi_ontology
has related synonym: glucans
id: CHEBI:37163
in subset: 3 STAR

Axiom
annotated source: glucan
annotated property: database_cross_reference
annotated target: CAS:9037-91-6
source: ChemIDplus

Axiom
annotated source: glucan
annotated property: has_exact_synonym
annotated target: Glucan
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glucan
annotated property: has_exact_synonym
annotated target: glucan
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: glucan
annotated property: hasRelatedSynonym
annotated target: glucans
database_cross_reference: ChEBI

homopolysaccharide
type: Class
subclass of: polysaccharide
definition: Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.
has_exact_synonym: homopolysaccharide
has OBO namespace: chebi_ontology
has related synonym: homoglycan
has related synonym: homopolysaccharides
id: CHEBI:37164
in subset: 3 STAR

Axiom
annotated source: homopolysaccharide
annotated property: has_exact_synonym
annotated target: homopolysaccharide
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: homopolysaccharide
annotated property: hasRelatedSynonym
annotated target: homoglycan
database_cross_reference: IUPAC

Axiom
annotated source: homopolysaccharide
annotated property: hasRelatedSynonym
annotated target: homopolysaccharides
database_cross_reference: ChEBI

organic hydride
type: Class
subclass of: hydrides
has OBO namespace: chebi_ontology
has related synonym: organic hydrides
id: CHEBI:37175
in subset: 3 STAR

Axiom
annotated source: organic hydride
annotated property: hasRelatedSynonym
annotated target: organic hydrides
database_cross_reference: ChEBI

mononuclear parent hydride
type: Class
subclass of: hydrides
has_exact_synonym: mononuclear parent hydrides
has OBO namespace: chebi_ontology
has related synonym: mononuclear hydride
has related synonym: mononuclear hydrides
id: CHEBI:37176
in subset: 3 STAR

Axiom
annotated source: mononuclear parent hydride
annotated property: has_exact_synonym
annotated target: mononuclear parent hydrides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: mononuclear parent hydride
annotated property: hasRelatedSynonym
annotated target: mononuclear hydride
database_cross_reference: ChEBI

Axiom
annotated source: mononuclear parent hydride
annotated property: hasRelatedSynonym
annotated target: mononuclear hydrides
database_cross_reference: IUPAC

elemental sodium
type: Class
subclass of: sodium molecular entity
has OBO namespace: chebi_ontology
id: CHEBI:37246
in subset: 3 STAR

mucopolysaccharide
type: Class
subclass of: glycosaminoglycan
definition: Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid.
has alternative id: CHEBI:25425
has alternative id: CHEBI:7011
database_cross_reference: KEGG:C05114
has_exact_synonym: Mucopolysaccharide
has_exact_synonym: mucopolysaccharides
has OBO namespace: chebi_ontology
has related synonym: Mucopolysaccharid
has related synonym: Mukopolysaccharid
has related synonym: mucopolisacarido
has related synonym: mucopolisacaridos
id: CHEBI:37395
in subset: 3 STAR

Axiom
annotated source: mucopolysaccharide
annotated property: has_exact_synonym
annotated target: Mucopolysaccharide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: mucopolysaccharide
annotated property: has_exact_synonym
annotated target: mucopolysaccharides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: mucopolysaccharide
annotated property: hasRelatedSynonym
annotated target: Mucopolysaccharid
database_cross_reference: ChEBI

Axiom
annotated source: mucopolysaccharide
annotated property: hasRelatedSynonym
annotated target: Mukopolysaccharid
database_cross_reference: ChEBI

Axiom
annotated source: mucopolysaccharide
annotated property: hasRelatedSynonym
annotated target: mucopolisacarido
database_cross_reference: ChEBI

Axiom
annotated source: mucopolysaccharide
annotated property: hasRelatedSynonym
annotated target: mucopolisacaridos
database_cross_reference: IUPAC

acid
type: Class
subclass of: chemical role
definition: An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
has alternative id: CHEBI:13800
has alternative id: CHEBI:13801
has alternative id: CHEBI:22209
has alternative id: CHEBI:2426
database_cross_reference: KEGG:C00174
has_exact_synonym: Acid
has_exact_synonym: acid
has OBO namespace: chebi_ontology
has related synonym: Saeure
has related synonym: Saeuren
has related synonym: acide
has related synonym: acido
has related synonym: acids
id: CHEBI:37527
in subset: 3 STAR

Axiom
annotated source: acid
annotated property: has_exact_synonym
annotated target: Acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acid
annotated property: has_exact_synonym
annotated target: acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: acid
annotated property: hasRelatedSynonym
annotated target: Saeure
database_cross_reference: ChEBI

Axiom
annotated source: acid
annotated property: hasRelatedSynonym
annotated target: Saeuren
database_cross_reference: ChEBI

Axiom
annotated source: acid
annotated property: hasRelatedSynonym
annotated target: acide
database_cross_reference: IUPAC

Axiom
annotated source: acid
annotated property: hasRelatedSynonym
annotated target: acido
database_cross_reference: ChEBI

Axiom
annotated source: acid
annotated property: hasRelatedSynonym
annotated target: acids
database_cross_reference: ChEBI

heteroatomic molecular entity
type: Class
subclass of: polyatomic entity
definition: A molecular entity consisting of two or more chemical elements.
has OBO namespace: chebi_ontology
has related synonym: chemical compound
has related synonym: heteroatomic molecular entities
id: CHEBI:37577
in subset: 3 STAR

Axiom
annotated source: heteroatomic molecular entity
annotated property: hasRelatedSynonym
annotated target: chemical compound
database_cross_reference: ChEBI

Axiom
annotated source: heteroatomic molecular entity
annotated property: hasRelatedSynonym
annotated target: heteroatomic molecular entities
database_cross_reference: ChEBI

carboxamide
type: Class
subclass of: primary amide
subclass of: organonitrogen compound
subclass of: organooxygen compound
subclass of: Restriction
  on property: has part
  some values from: carbamoyl group
definition: An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom.
has alternative id: CHEBI:35354
has alternative id: CHEBI:35355
has_exact_synonym: carboxamides
has OBO namespace: chebi_ontology
has related synonym: carboxamides
has related synonym: primary carboxamide
id: CHEBI:37622
in subset: 3 STAR

Axiom
annotated source: carboxamide
annotated property: has_exact_synonym
annotated target: carboxamides
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carboxamide
annotated property: hasRelatedSynonym
annotated target: carboxamides
database_cross_reference: ChEBI

Axiom
annotated source: carboxamide
annotated property: hasRelatedSynonym
annotated target: primary carboxamide
database_cross_reference: ChEBI

glucopyranose
type: Class
subclass of: glucose
has_exact_synonym: glucopyranose
has OBO namespace: chebi_ontology
id: CHEBI:37661
in subset: 3 STAR

Axiom
annotated source: glucopyranose
annotated property: has_exact_synonym
annotated target: glucopyranose
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

sulfuric acid derivative
type: Class
subclass of: sulfur oxoacid derivative
subclass of: Restriction
  on property: has functional parent
  some values from: sulfuric acid
has_exact_synonym: sulfuric acid derivative
has OBO namespace: chebi_ontology
has related synonym: sulfuric acid derivatives
id: CHEBI:37826
in subset: 3 STAR

Axiom
annotated source: sulfuric acid derivative
annotated property: has_exact_synonym
annotated target: sulfuric acid derivative
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric acid derivative
annotated property: hasRelatedSynonym
annotated target: sulfuric acid derivatives
database_cross_reference: ChEBI

carboacyl group
type: Class
subclass of: acyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carboxylic acid
definition: A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid.
has_exact_synonym: carboacyl groups
has_exact_synonym: carboxylic acyl group
has OBO namespace: chebi_ontology
has related synonym: carboxylic acyl groups
id: CHEBI:37838
in subset: 3 STAR

Axiom
annotated source: carboacyl group
annotated property: has_exact_synonym
annotated target: carboacyl groups
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carboacyl group
annotated property: has_exact_synonym
annotated target: carboxylic acyl group
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carboacyl group
annotated property: hasRelatedSynonym
annotated target: carboxylic acyl groups
database_cross_reference: IUPAC

adrenergic agonist
type: Class
subclass of: adrenergic agent
definition: An agent that selectively binds to and activates adrenergic receptors.
has OBO namespace: chebi_ontology
has related synonym: adrenergic agonists
has related synonym: adrenergic receptor agonist
has related synonym: adrenoceptor agonists
has related synonym: adrenomimetic
has related synonym: adrenomimetics
id: CHEBI:37886
in subset: 3 STAR

Axiom
annotated source: adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: adrenergic agonists
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: adrenergic receptor agonist
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: adrenoceptor agonists
database_cross_reference: IUPHAR

Axiom
annotated source: adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: adrenomimetic
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agonist
annotated property: hasRelatedSynonym
annotated target: adrenomimetics
database_cross_reference: ChEBI

adrenergic agent
type: Class
subclass of: neurotransmitter agent
definition: Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
has OBO namespace: chebi_ontology
has related synonym: adrenergic agents
has related synonym: adrenergic drug
has related synonym: adrenergic drugs
has related synonym: adrenergic neuron agents
has related synonym: adrenergics
id: CHEBI:37962
in subset: 3 STAR

Axiom
annotated source: adrenergic agent
annotated property: hasRelatedSynonym
annotated target: adrenergic agents
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: hasRelatedSynonym
annotated target: adrenergic drug
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: hasRelatedSynonym
annotated target: adrenergic drugs
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: hasRelatedSynonym
annotated target: adrenergic neuron agents
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: hasRelatedSynonym
annotated target: adrenergics
database_cross_reference: ChEBI

polypyrrole
type: Class
subclass of: organonitrogen heterocyclic compound
definition: A compound composed of two or more pyrrole units.
database_cross_reference: Beilstein:8538310
has OBO namespace: chebi_ontology
has related synonym: PPys
has related synonym: poly(pyrrole)s
has related synonym: polypyrroles
id: CHEBI:38077
in subset: 3 STAR

Axiom
annotated source: polypyrrole
annotated property: database_cross_reference
annotated target: Beilstein:8538310
source: Beilstein

Axiom
annotated source: polypyrrole
annotated property: hasRelatedSynonym
annotated target: PPys
database_cross_reference: ChEBI

Axiom
annotated source: polypyrrole
annotated property: hasRelatedSynonym
annotated target: poly(pyrrole)s
database_cross_reference: ChEBI

Axiom
annotated source: polypyrrole
annotated property: hasRelatedSynonym
annotated target: polypyrroles
database_cross_reference: ChEBI

organonitrogen heterocyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: organonitrogen compound
definition: Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.
has OBO namespace: chebi_ontology
has related synonym: heterocyclic organonitrogen compounds
has related synonym: organonitrogen heterocyclic compounds
id: CHEBI:38101
in subset: 3 STAR

Axiom
annotated source: organonitrogen heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: heterocyclic organonitrogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: organonitrogen heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: organonitrogen heterocyclic compounds
database_cross_reference: ChEBI

organic heteropolycyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heteropolycyclic compound
has alternative id: CHEBI:25429
has alternative id: CHEBI:38075
has OBO namespace: chebi_ontology
has related synonym: organic heteropolycyclic compounds
id: CHEBI:38166
in subset: 3 STAR

Axiom
annotated source: organic heteropolycyclic compound
annotated property: hasRelatedSynonym
annotated target: organic heteropolycyclic compounds
database_cross_reference: ChEBI

polycyclic heteroarene
type: Class
subclass of: heteroarene
has OBO namespace: chebi_ontology
has related synonym: polycyclic heteroarenes
id: CHEBI:38180
in subset: 3 STAR

Axiom
annotated source: polycyclic heteroarene
annotated property: hasRelatedSynonym
annotated target: polycyclic heteroarenes
database_cross_reference: ChEBI

cholinergic drug
type: Class
subclass of: neurotransmitter agent
definition: Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
has OBO namespace: chebi_ontology
has related synonym: cholinergic agent
has related synonym: cholinergic drugs
has related synonym: cholinomimetic
id: CHEBI:38323
in subset: 3 STAR

Axiom
annotated source: cholinergic drug
annotated property: hasRelatedSynonym
annotated target: cholinergic agent
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic drug
annotated property: hasRelatedSynonym
annotated target: cholinergic drugs
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic drug
annotated property: hasRelatedSynonym
annotated target: cholinomimetic
database_cross_reference: ChEBI

cholinergic agonist
type: Class
subclass of: cholinergic drug
definition: Any drug that binds to and activates cholinergic receptors.
has OBO namespace: chebi_ontology
has related synonym: acetylcholine agonist
has related synonym: acetylcholine agonists
has related synonym: acetylcholine receptor agonist
has related synonym: cholinergic agonists
has related synonym: cholinomimetic
has related synonym: cholinomimetics
id: CHEBI:38324
in subset: 3 STAR

Axiom
annotated source: cholinergic agonist
annotated property: hasRelatedSynonym
annotated target: acetylcholine agonist
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: hasRelatedSynonym
annotated target: acetylcholine agonists
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: hasRelatedSynonym
annotated target: acetylcholine receptor agonist
database_cross_reference: IUPHAR

Axiom
annotated source: cholinergic agonist
annotated property: hasRelatedSynonym
annotated target: cholinergic agonists
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: hasRelatedSynonym
annotated target: cholinomimetic
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: hasRelatedSynonym
annotated target: cholinomimetics
database_cross_reference: ChEBI

muscarinic agonist
type: Class
subclass of: cholinergic agonist
definition: Any drug that binds to and activates a muscarinic cholinergic receptor.
has OBO namespace: chebi_ontology
has related synonym: muscarinic acetylcholine receptor agonist
has related synonym: muscarinic agonists
has related synonym: muscarinic cholinergic agonist
has related synonym: muscarinic cholinergic agonists
id: CHEBI:38325
in subset: 3 STAR

Axiom
annotated source: muscarinic agonist
annotated property: hasRelatedSynonym
annotated target: muscarinic acetylcholine receptor agonist
database_cross_reference: ChEBI

Axiom
annotated source: muscarinic agonist
annotated property: hasRelatedSynonym
annotated target: muscarinic agonists
database_cross_reference: ChEBI

Axiom
annotated source: muscarinic agonist
annotated property: hasRelatedSynonym
annotated target: muscarinic cholinergic agonist
database_cross_reference: ChEBI

Axiom
annotated source: muscarinic agonist
annotated property: hasRelatedSynonym
annotated target: muscarinic cholinergic agonists
database_cross_reference: ChEBI

aminoalkylindole
type: Class
subclass of: indoles
has alternative id: CHEBI:22503
has alternative id: CHEBI:24792
has OBO namespace: chebi_ontology
has related synonym: aminoalkylindoles
id: CHEBI:38631
in subset: 3 STAR

Axiom
annotated source: aminoalkylindole
annotated property: hasRelatedSynonym
annotated target: aminoalkylindoles
database_cross_reference: ChEBI

organic sodium salt
type: Class
subclass of: organic salt
subclass of: sodium salt
has_exact_synonym: organic sodium salt
has OBO namespace: chebi_ontology
has related synonym: organic sodium salts
id: CHEBI:38700
in subset: 3 STAR

Axiom
annotated source: organic sodium salt
annotated property: has_exact_synonym
annotated target: organic sodium salt
database_cross_reference: ChEBI

Axiom
annotated source: organic sodium salt
annotated property: hasRelatedSynonym
annotated target: organic sodium salts
database_cross_reference: ChEBI

carboxylic acid dianion
type: Class
subclass of: carboxylic acid anion
definition: Any dianion containing at least one carboxy group.
has_exact_synonym: carboxylic acid dianion
has OBO namespace: chebi_ontology
has related synonym: carboxylic acid dianions
id: CHEBI:38716
in subset: 3 STAR

Axiom
annotated source: carboxylic acid dianion
annotated property: has_exact_synonym
annotated target: carboxylic acid dianion
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid dianion
annotated property: hasRelatedSynonym
annotated target: carboxylic acid dianions
database_cross_reference: ChEBI

indole alkaloid
type: Class
subclass of: alkaloid
subclass of: Restriction
  on property: has part
  some values from: indole skeleton
definition: An alkaloid containing an indole skeleton.
has alternative id: CHEBI:24795
has alternative id: CHEBI:5901
database_cross_reference: KEGG:C06073
database_cross_reference: Wikipedia:Indole_alkaloid
has_exact_synonym: Indole alkaloid
has OBO namespace: chebi_ontology
has related synonym: indole alkaloids
id: CHEBI:38958
in subset: 3 STAR

Axiom
annotated source: indole alkaloid
annotated property: has_exact_synonym
annotated target: Indole alkaloid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: indole alkaloid
annotated property: hasRelatedSynonym
annotated target: indole alkaloids
database_cross_reference: ChEBI

Bronsted acid
type: Class
subclass of: donor
subclass of: acid
definition: A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
has_exact_synonym: Bronsted acid
has OBO namespace: chebi_ontology
has related synonym: Bronsted-Saeure
has related synonym: acide de Bronsted
has related synonym: donneur d'hydron
has related synonym: hydron donor
id: CHEBI:39141
in subset: 3 STAR

Axiom
annotated source: Bronsted acid
annotated property: has_exact_synonym
annotated target: Bronsted acid
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: Bronsted acid
annotated property: hasRelatedSynonym
annotated target: Bronsted-Saeure
database_cross_reference: ChEBI

Axiom
annotated source: Bronsted acid
annotated property: hasRelatedSynonym
annotated target: acide de Bronsted
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted acid
annotated property: hasRelatedSynonym
annotated target: donneur d'hydron
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted acid
annotated property: hasRelatedSynonym
annotated target: hydron donor
database_cross_reference: IUPAC

Bronsted base
type: Class
subclass of: acceptor
subclass of: base
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
has_exact_synonym: Bronsted base
has OBO namespace: chebi_ontology
has related synonym: Bronsted-Base
has related synonym: accepteur d'hydron
has related synonym: base de Bronsted
has related synonym: hydron acceptor
id: CHEBI:39142
in subset: 3 STAR

Axiom
annotated source: Bronsted base
annotated property: has_exact_synonym
annotated target: Bronsted base
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: Bronsted base
annotated property: hasRelatedSynonym
annotated target: Bronsted-Base
database_cross_reference: ChEBI

Axiom
annotated source: Bronsted base
annotated property: hasRelatedSynonym
annotated target: accepteur d'hydron
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted base
annotated property: hasRelatedSynonym
annotated target: base de Bronsted
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted base
annotated property: hasRelatedSynonym
annotated target: hydron acceptor
database_cross_reference: IUPAC

Lewis base
type: Class
subclass of: donor
subclass of: base
definition: A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.
has_exact_synonym: Lewis base
has OBO namespace: chebi_ontology
has related synonym: Lewis-Base
has related synonym: base de Lewis
has related synonym: donneur d'une paire d'electrons
has related synonym: electron donor
id: CHEBI:39144
in subset: 3 STAR

Axiom
annotated source: Lewis base
annotated property: has_exact_synonym
annotated target: Lewis base
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: Lewis base
annotated property: hasRelatedSynonym
annotated target: Lewis-Base
database_cross_reference: ChEBI

Axiom
annotated source: Lewis base
annotated property: hasRelatedSynonym
annotated target: base de Lewis
database_cross_reference: IUPAC

Axiom
annotated source: Lewis base
annotated property: hasRelatedSynonym
annotated target: donneur d'une paire d'electrons
database_cross_reference: ChEBI

Axiom
annotated source: Lewis base
annotated property: hasRelatedSynonym
annotated target: electron donor
database_cross_reference: ChEBI

carbonate
type: Class
subclass of: carbon oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogencarbonate
has alternative id: CHEBI:29201
has alternative id: CHEBI:41605
database_cross_reference: Beilstein:3600898
database_cross_reference: CAS:3812-32-6
database_cross_reference: Gmelin:1559
database_cross_reference: PDBeChem:CO3
has_exact_synonym: carbonate
has_exact_synonym: trioxidocarbonate(2-)
has OBO namespace: chebi_ontology
has related synonym: CARBONATE ION
has related synonym: CO3(2-)
has related synonym: Karbonat
has related synonym: [CO3](2-)
id: CHEBI:41609
in subset: 3 STAR

Axiom
annotated source: carbonate
annotated property: database_cross_reference
annotated target: Beilstein:3600898
source: Beilstein

Axiom
annotated source: carbonate
annotated property: database_cross_reference
annotated target: CAS:3812-32-6
source: ChemIDplus

Axiom
annotated source: carbonate
annotated property: database_cross_reference
annotated target: Gmelin:1559
source: Gmelin

Axiom
annotated source: carbonate
annotated property: has_exact_synonym
annotated target: carbonate
database_cross_reference: IUPAC

Axiom
annotated source: carbonate
annotated property: has_exact_synonym
annotated target: trioxidocarbonate(2-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carbonate
annotated property: hasRelatedSynonym
annotated target: CARBONATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: carbonate
annotated property: hasRelatedSynonym
annotated target: CO3(2-)
database_cross_reference: ChEBI

Axiom
annotated source: carbonate
annotated property: hasRelatedSynonym
annotated target: Karbonat
database_cross_reference: ChEBI

Axiom
annotated source: carbonate
annotated property: hasRelatedSynonym
annotated target: [CO3](2-)
database_cross_reference: IUPAC

D-glucopyranose
type: Class
subclass of: D-glucose
subclass of: glucopyranose
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
definition: A glucopyranose having D-configuration.
database_cross_reference: CAS:2280-44-6
database_cross_reference: GlyGen:G15021LG
database_cross_reference: GlyTouCan:G15021LG
database_cross_reference: Gmelin:83256
database_cross_reference: HMDB:HMDB0000122
database_cross_reference: KEGG:C00031
database_cross_reference: KEGG:D00009
database_cross_reference: KNApSAcK:C00001122
database_cross_reference: MetaCyc:D-Glucose
database_cross_reference: PMID:15987845
database_cross_reference: PMID:16901854
database_cross_reference: PMID:17336832
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17928662
database_cross_reference: PMID:19913595
database_cross_reference: PMID:26812026
database_cross_reference: PMID:32619908
database_cross_reference: PMID:7524207
database_cross_reference: PMID:9140037
database_cross_reference: PMID:9501190
database_cross_reference: PMID:9506998
database_cross_reference: PMID:9545565
database_cross_reference: Reaxys:1281604
database_cross_reference: Wikipedia:Glucose
has_exact_synonym: D-glucopyranose
has OBO namespace: chebi_ontology
has related synonym: D-Glc
has related synonym: D-Glcp
has related synonym: D-Glucose
has related synonym: D-glucose
has related synonym: Dextrose
has related synonym: Glc-OH
has related synonym: Glucose
has related synonym: Grape sugar
has related synonym: WURCS=2.0/1,1,0/[a2122h-1x_1-5]/1/
has related synonym: glucose
id: CHEBI:4167
in subset: 3 STAR

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: CAS:2280-44-6
source: ChemIDplus

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: Gmelin:83256
source: Gmelin

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:15987845
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:16901854
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:17336832
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:17439666
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:17928662
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:19913595
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:26812026
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:32619908
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:7524207
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:9140037
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:9501190
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:9506998
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: PMID:9545565
source: Europe PMC

Axiom
annotated source: D-glucopyranose
annotated property: database_cross_reference
annotated target: Reaxys:1281604
source: Reaxys

Axiom
annotated source: D-glucopyranose
annotated property: has_exact_synonym
annotated target: D-glucopyranose
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: D-Glc
database_cross_reference: ChEBI

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: D-Glcp
database_cross_reference: ChEBI

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: D-Glucose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: D-glucose
database_cross_reference: UniProt

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: Dextrose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: Glc-OH
database_cross_reference: ChEBI

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: Glucose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: Grape sugar
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: WURCS=2.0/1,1,0/[a2122h-1x_1-5]/1/
database_cross_reference: GlyTouCan

Axiom
annotated source: D-glucopyranose
annotated property: hasRelatedSynonym
annotated target: glucose
database_cross_reference: ChEBI

D-hexose
type: Class
subclass of: hexose
definition: A hexose that has D-configuration at position 5.
database_cross_reference: KEGG:C00738
has_exact_synonym: D-Hexose
has_exact_synonym: D-hexopyranose
has OBO namespace: chebi_ontology
has related synonym: D-hexoses
has related synonym: a D-hexose
id: CHEBI:4194
in subset: 3 STAR

Axiom
annotated source: D-hexose
annotated property: has_exact_synonym
annotated target: D-Hexose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: D-hexose
annotated property: has_exact_synonym
annotated target: D-hexopyranose
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: D-hexose
annotated property: hasRelatedSynonym
annotated target: D-hexoses
database_cross_reference: ChEBI

Axiom
annotated source: D-hexose
annotated property: hasRelatedSynonym
annotated target: a D-hexose
database_cross_reference: UniProt

hydroxy group
type: Class
subclass of: inorganic group
has alternative id: CHEBI:24706
has alternative id: CHEBI:43171
database_cross_reference: PDBeChem:OH
has_exact_synonym: HYDROXY GROUP
has_exact_synonym: hydroxy
has_exact_synonym: hydroxy group
has OBO namespace: chebi_ontology
has related synonym: -OH
has related synonym: hydroxyl
has related synonym: hydroxyl group
id: CHEBI:43176
in subset: 3 STAR

Axiom
annotated source: hydroxy group
annotated property: has_exact_synonym
annotated target: HYDROXY GROUP
database_cross_reference: PDBeChem

Axiom
annotated source: hydroxy group
annotated property: has_exact_synonym
annotated target: hydroxy
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydroxy group
annotated property: has_exact_synonym
annotated target: hydroxy group
database_cross_reference: UniProt

Axiom
annotated source: hydroxy group
annotated property: hasRelatedSynonym
annotated target: -OH
database_cross_reference: IUPAC

Axiom
annotated source: hydroxy group
annotated property: hasRelatedSynonym
annotated target: hydroxyl
database_cross_reference: ChEBI

Axiom
annotated source: hydroxy group
annotated property: hasRelatedSynonym
annotated target: hydroxyl group
database_cross_reference: ChEBI

hydrogensulfate
type: Class
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: sulfate
subclass of: Restriction
  on property: is conjugate base of
  some values from: sulfuric acid
has alternative id: CHEBI:29199
has alternative id: CHEBI:45693
database_cross_reference: Gmelin:2121
has_exact_synonym: hydrogen(tetraoxidosulfate)(1-)
has_exact_synonym: hydrogensulfate
has_exact_synonym: hydrogensulfate(1-)
has_exact_synonym: hydrogentetraoxosulfate(1-)
has_exact_synonym: hydrogentetraoxosulfate(VI)
has_exact_synonym: hydroxidotrioxidosulfate(1-)
has OBO namespace: chebi_ontology
has related synonym: HSO4(-)
has related synonym: HYDROGEN SULFATE
has related synonym: [SO3(OH)](-)
id: CHEBI:45696
in subset: 3 STAR

Axiom
annotated source: hydrogensulfate
annotated property: database_cross_reference
annotated target: Gmelin:2121
source: Gmelin

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogen(tetraoxidosulfate)(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogensulfate
database_cross_reference: IUPAC

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogensulfate(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogentetraoxosulfate(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogentetraoxosulfate(VI)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydroxidotrioxidosulfate(1-)
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: hasRelatedSynonym
annotated target: HSO4(-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogensulfate
annotated property: hasRelatedSynonym
annotated target: HYDROGEN SULFATE
database_cross_reference: PDBeChem

Axiom
annotated source: hydrogensulfate
annotated property: hasRelatedSynonym
annotated target: [SO3(OH)](-)
database_cross_reference: IUPAC

oxo group
type: Class
subclass of: inorganic group
has alternative id: CHEBI:29353
has alternative id: CHEBI:44607
database_cross_reference: PDBeChem:O
has_exact_synonym: OXO GROUP
has_exact_synonym: oxo
has OBO namespace: chebi_ontology
has related synonym: =O
id: CHEBI:46629
in subset: 3 STAR

Axiom
annotated source: oxo group
annotated property: has_exact_synonym
annotated target: OXO GROUP
database_cross_reference: PDBeChem

Axiom
annotated source: oxo group
annotated property: has_exact_synonym
annotated target: oxo
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: oxo group
annotated property: hasRelatedSynonym
annotated target: =O
database_cross_reference: IUPAC

solvent
type: Class
subclass of: application
subclass of: chemical role
definition: A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
database_cross_reference: Wikipedia:Solvent
has OBO namespace: chebi_ontology
has related synonym: Loesungsmittel
has related synonym: solvant
has related synonym: solvents
id: CHEBI:46787
in subset: 3 STAR

Axiom
annotated source: solvent
annotated property: hasRelatedSynonym
annotated target: Loesungsmittel
database_cross_reference: ChEBI

Axiom
annotated source: solvent
annotated property: hasRelatedSynonym
annotated target: solvant
database_cross_reference: ChEBI

Axiom
annotated source: solvent
annotated property: hasRelatedSynonym
annotated target: solvents
database_cross_reference: ChEBI

carboxy group
type: Class
subclass of: organyl group
has alternative id: CHEBI:23025
has alternative id: CHEBI:41420
database_cross_reference: PDBeChem:FMT
has_exact_synonym: CARBOXY GROUP
has_exact_synonym: carboxy
has OBO namespace: chebi_ontology
has related synonym: -C(O)OH
has related synonym: -CO2H
has related synonym: -COOH
has related synonym: carboxyl group
id: CHEBI:46883
in subset: 3 STAR

Axiom
annotated source: carboxy group
annotated property: has_exact_synonym
annotated target: CARBOXY GROUP
database_cross_reference: PDBeChem

Axiom
annotated source: carboxy group
annotated property: has_exact_synonym
annotated target: carboxy
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: carboxy group
annotated property: hasRelatedSynonym
annotated target: -C(O)OH
database_cross_reference: IUPAC

Axiom
annotated source: carboxy group
annotated property: hasRelatedSynonym
annotated target: -CO2H
database_cross_reference: ChEBI

Axiom
annotated source: carboxy group
annotated property: hasRelatedSynonym
annotated target: -COOH
database_cross_reference: IUPAC

Axiom
annotated source: carboxy group
annotated property: hasRelatedSynonym
annotated target: carboxyl group
database_cross_reference: ChEBI

acetate ester
type: Class
subclass of: carboxylic ester
subclass of: Restriction
  on property: has functional parent
  some values from: acetic acid
definition: Any carboxylic ester where the carboxylic acid component is acetic acid.
has alternative id: CHEBI:13244
has alternative id: CHEBI:13799
has alternative id: CHEBI:22189
has alternative id: CHEBI:2406
database_cross_reference: KEGG:C01883
database_cross_reference: Wikipedia:Acetate#Esters
has OBO namespace: chebi_ontology
has related synonym: Acetic ester
has related synonym: Acetyl ester
has related synonym: acetate
has related synonym: acetate esters
has related synonym: acetates
has related synonym: acetyl esters
has related synonym: an acetyl ester
id: CHEBI:47622
in subset: 3 STAR

Axiom
annotated source: acetate ester
annotated property: hasRelatedSynonym
annotated target: Acetic ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetate ester
annotated property: hasRelatedSynonym
annotated target: Acetyl ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetate ester
annotated property: hasRelatedSynonym
annotated target: acetate
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: hasRelatedSynonym
annotated target: acetate esters
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: hasRelatedSynonym
annotated target: acetates
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: hasRelatedSynonym
annotated target: acetyl esters
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: hasRelatedSynonym
annotated target: an acetyl ester
database_cross_reference: UniProt

steroid acid
type: Class
subclass of: steroid
subclass of: organic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: steroid acid anion
definition: Any steroid substituted by at least one carboxy group.
has OBO namespace: chebi_ontology
has related synonym: steroid acids
id: CHEBI:47891
in subset: 3 STAR

Axiom
annotated source: steroid acid
annotated property: hasRelatedSynonym
annotated target: steroid acids
database_cross_reference: ChEBI

sulfur oxide
type: Class
subclass of: inorganic oxide
subclass of: sulfur molecular entity
has OBO namespace: chebi_ontology
has related synonym: Schwefeloxide
has related synonym: oxides of sulfur
has related synonym: sulfur oxides
id: CHEBI:48154
in subset: 3 STAR

Axiom
annotated source: sulfur oxide
annotated property: hasRelatedSynonym
annotated target: Schwefeloxide
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxide
annotated property: hasRelatedSynonym
annotated target: oxides of sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxide
annotated property: hasRelatedSynonym
annotated target: sulfur oxides
database_cross_reference: ChEBI

polar solvent
type: Class
subclass of: solvent
definition: A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
has_exact_synonym: polar solvent
has OBO namespace: chebi_ontology
has related synonym: polar solvents
id: CHEBI:48354
in subset: 3 STAR

Axiom
annotated source: polar solvent
annotated property: has_exact_synonym
annotated target: polar solvent
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: polar solvent
annotated property: hasRelatedSynonym
annotated target: polar solvents
database_cross_reference: ChEBI

protic solvent
type: Class
subclass of: Bronsted acid
subclass of: polar solvent
definition: A polar solvent that is capable of acting as a hydron (proton) donor.
has_exact_synonym: protogenic solvent
has OBO namespace: chebi_ontology
id: CHEBI:48356
in subset: 3 STAR

Axiom
annotated source: protic solvent
annotated property: has_exact_synonym
annotated target: protogenic solvent
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

alpha-adrenergic drug
type: Class
subclass of: adrenergic agent
definition: Any drug that acts on an alpha-adrenergic receptor.
has OBO namespace: chebi_ontology
has related synonym: alpha-adrenergic drugs
id: CHEBI:48539
in subset: 3 STAR

Axiom
annotated source: alpha-adrenergic drug
annotated property: hasRelatedSynonym
annotated target: alpha-adrenergic drugs
database_cross_reference: ChEBI

agonist
type: Class
subclass of: pharmacological role
definition: Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
has_exact_synonym: agonist
has OBO namespace: chebi_ontology
has related synonym: agonista
has related synonym: agoniste
has related synonym: agonists
id: CHEBI:48705
in subset: 3 STAR

Axiom
annotated source: agonist
annotated property: has_exact_synonym
annotated target: agonist
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: agonist
annotated property: hasRelatedSynonym
annotated target: agonista
database_cross_reference: ChEBI

Axiom
annotated source: agonist
annotated property: hasRelatedSynonym
annotated target: agoniste
database_cross_reference: ChEBI

Axiom
annotated source: agonist
annotated property: hasRelatedSynonym
annotated target: agonists
database_cross_reference: ChEBI

hydrogen atom
type: Class
subclass of: independent continuant
subclass of: inorganic molecular entity
subclass of: nonmetal atom
subclass of: s-block element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
has alternative id: CHEBI:24634
has alternative id: CHEBI:49636
database_cross_reference: WebElements:H
has_exact_synonym: hydrogen
has OBO namespace: chebi_ontology
has related synonym: 1H
has related synonym: H
has related synonym: Wasserstoff
has related synonym: hidrogeno
has related synonym: hydrogen
has related synonym: hydrogene
id: CHEBI:49637
in subset: 3 STAR

Axiom
annotated source: hydrogen atom
annotated property: has_exact_synonym
annotated target: hydrogen
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: hydrogen atom
annotated property: hasRelatedSynonym
annotated target: 1H
database_cross_reference: IUPAC

Axiom
annotated source: hydrogen atom
annotated property: hasRelatedSynonym
annotated target: H
database_cross_reference: IUPAC

Axiom
annotated source: hydrogen atom
annotated property: hasRelatedSynonym
annotated target: Wasserstoff
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen atom
annotated property: hasRelatedSynonym
annotated target: hidrogeno
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen atom
annotated property: hasRelatedSynonym
annotated target: hydrogen
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen atom
annotated property: hasRelatedSynonym
annotated target: hydrogene
database_cross_reference: ChEBI

organic amino compound
type: Class
subclass of: independent continuant
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has role
  some values from: Bronsted base
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonia
definition: A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups.
has OBO namespace: chebi_ontology
has related synonym: organic amino compounds
id: CHEBI:50047
in subset: 3 STAR

Axiom
annotated source: organic amino compound
annotated property: hasRelatedSynonym
annotated target: organic amino compounds
database_cross_reference: ChEBI

steroid acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: steroid acid
definition: Any anion formed by loss of a proton from a steroid acid.
has OBO namespace: chebi_ontology
has related synonym: steroid acid anions
id: CHEBI:50160
in subset: 3 STAR

Axiom
annotated source: steroid acid anion
annotated property: hasRelatedSynonym
annotated target: steroid acid anions
database_cross_reference: ChEBI

canonical nucleotide residue
type: Class
subclass of: nucleotide residue
has OBO namespace: chebi_ontology
has related synonym: canonical nucleotide residues
id: CHEBI:50297
in subset: 3 STAR

Axiom
annotated source: canonical nucleotide residue
annotated property: hasRelatedSynonym
annotated target: canonical nucleotide residues
database_cross_reference: ChEBI

canonical ribonucleotide residue
type: Class
subclass of: canonical nucleotide residue
has OBO namespace: chebi_ontology
has related synonym: canonical ribonucleotide residues
id: CHEBI:50299
in subset: 3 STAR

Axiom
annotated source: canonical ribonucleotide residue
annotated property: hasRelatedSynonym
annotated target: canonical ribonucleotide residues
database_cross_reference: ChEBI

onium compound
type: Class
subclass of: heteroatomic molecular entity
has OBO namespace: chebi_ontology
id: CHEBI:50312
in subset: 1 STAR

onium cation
type: Class
subclass of: onium compound
definition: Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.
has_exact_synonym: onium cations
has OBO namespace: chebi_ontology
has related synonym: onium cations
has related synonym: onium ion
has related synonym: onium ions
id: CHEBI:50313
in subset: 3 STAR

Axiom
annotated source: onium cation
annotated property: has_exact_synonym
annotated target: onium cations
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: onium cation
annotated property: hasRelatedSynonym
annotated target: onium cations
database_cross_reference: ChEBI

Axiom
annotated source: onium cation
annotated property: hasRelatedSynonym
annotated target: onium ion
database_cross_reference: ChEBI

Axiom
annotated source: onium cation
annotated property: hasRelatedSynonym
annotated target: onium ions
database_cross_reference: ChEBI

nucleotide residue
type: Class
subclass of: organic group
has OBO namespace: chebi_ontology
has related synonym: nucleotide residues
id: CHEBI:50319
in subset: 3 STAR

Axiom
annotated source: nucleotide residue
annotated property: hasRelatedSynonym
annotated target: nucleotide residues
database_cross_reference: ChEBI

nucleoside residue
type: Class
subclass of: organic group
has OBO namespace: chebi_ontology
has related synonym: nucleoside residues
id: CHEBI:50320
in subset: 3 STAR

Axiom
annotated source: nucleoside residue
annotated property: hasRelatedSynonym
annotated target: nucleoside residues
database_cross_reference: ChEBI

vasoconstrictor agent
type: Class
subclass of: cardiovascular drug
definition: Drug used to cause constriction of the blood vessels.
has OBO namespace: chebi_ontology
id: CHEBI:50514
in subset: 3 STAR

organic molecular entity
type: Class
subclass of: carbon group molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon atom
definition: Any molecular entity that contains carbon.
has alternative id: CHEBI:25700
has alternative id: CHEBI:33244
has OBO namespace: chebi_ontology
has related synonym: organic compounds
has related synonym: organic entity
has related synonym: organic molecular entities
id: CHEBI:50860
in subset: 3 STAR

Axiom
annotated source: organic molecular entity
annotated property: hasRelatedSynonym
annotated target: organic compounds
database_cross_reference: ChEBI

Axiom
annotated source: organic molecular entity
annotated property: hasRelatedSynonym
annotated target: organic entity
database_cross_reference: ChEBI

Axiom
annotated source: organic molecular entity
annotated property: hasRelatedSynonym
annotated target: organic molecular entities
database_cross_reference: ChEBI

role
type: Class
definition: A role is particular behaviour which a material entity may exhibit.
has OBO namespace: chebi_ontology
id: CHEBI:50906
in subset: 3 STAR

neurotoxin
type: Class
subclass of: aetiopathogenetic role
subclass of: poison
definition: A poison that interferes with the functions of the nervous system.
has alternative id: CHEBI:50911
database_cross_reference: Wikipedia:Neurotoxin
has OBO namespace: chebi_ontology
has related synonym: agente neurotoxico
has related synonym: nerve poison
has related synonym: nerve poisons
has related synonym: neurotoxic agent
has related synonym: neurotoxic agents
has related synonym: neurotoxicant
has related synonym: neurotoxins
id: CHEBI:50910
in subset: 3 STAR

Axiom
annotated source: neurotoxin
annotated property: hasRelatedSynonym
annotated target: agente neurotoxico
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: hasRelatedSynonym
annotated target: nerve poison
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: hasRelatedSynonym
annotated target: nerve poisons
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: hasRelatedSynonym
annotated target: neurotoxic agent
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: hasRelatedSynonym
annotated target: neurotoxic agents
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: hasRelatedSynonym
annotated target: neurotoxicant
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: hasRelatedSynonym
annotated target: neurotoxins
database_cross_reference: ChEBI

primary amino compound
type: Class
subclass of: organic amino compound
subclass of: Restriction
  on property: is conjugate base of
  some values from: primary ammonium ion
definition: A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group.
has OBO namespace: chebi_ontology
has related synonym: primary amino compounds
id: CHEBI:50994
in subset: 3 STAR

Axiom
annotated source: primary amino compound
annotated property: hasRelatedSynonym
annotated target: primary amino compounds
database_cross_reference: ChEBI

chemical role
type: Class
subclass of: role
definition: A role played by the molecular entity or part thereof within a chemical context.
has OBO namespace: chebi_ontology
id: CHEBI:51086
in subset: 3 STAR

nitrogen molecular entity
type: Class
subclass of: pnictogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: nitrogen atom
has alternative id: CHEBI:25556
has alternative id: CHEBI:7594
database_cross_reference: KEGG:C06061
has OBO namespace: chebi_ontology
has related synonym: Nitrogenous compounds
has related synonym: nitrogen compounds
has related synonym: nitrogen molecular entities
id: CHEBI:51143
in subset: 3 STAR

Axiom
annotated source: nitrogen molecular entity
annotated property: hasRelatedSynonym
annotated target: Nitrogenous compounds
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: nitrogen molecular entity
annotated property: hasRelatedSynonym
annotated target: nitrogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: nitrogen molecular entity
annotated property: hasRelatedSynonym
annotated target: nitrogen molecular entities
database_cross_reference: ChEBI

dipolar compound
type: Class
subclass of: organic molecule
definition: An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case.
has OBO namespace: chebi_ontology
has related synonym: dipolar compounds
id: CHEBI:51151
in subset: 3 STAR

Axiom
annotated source: dipolar compound
annotated property: hasRelatedSynonym
annotated target: dipolar compounds
database_cross_reference: ChEBI

organodiyl group
type: Class
subclass of: organic divalent group
definition: Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s).
has OBO namespace: chebi_ontology
has related synonym: organodiyl groups
id: CHEBI:51422
in subset: 3 STAR

Axiom
annotated source: organodiyl group
annotated property: hasRelatedSynonym
annotated target: organodiyl groups
database_cross_reference: ChEBI

organic divalent group
type: Class
subclass of: organic group
has OBO namespace: chebi_ontology
id: CHEBI:51446
in subset: 1 STAR

organic univalent group
type: Class
subclass of: organic group
has OBO namespace: chebi_ontology
id: CHEBI:51447
in subset: 1 STAR

organic polycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: organic cyclic compound
has OBO namespace: chebi_ontology
has related synonym: organic polycyclic compounds
id: CHEBI:51958
in subset: 3 STAR

Axiom
annotated source: organic polycyclic compound
annotated property: hasRelatedSynonym
annotated target: organic polycyclic compounds
database_cross_reference: ChEBI

biochemical role
type: Class
subclass of: biological role
definition: A biological role played by the molecular entity or part thereof within a biochemical context.
has OBO namespace: chebi_ontology
id: CHEBI:52206
in subset: 3 STAR

aetiopathogenetic role
type: Class
subclass of: biological role
definition: A role played by the molecular entity or part thereof which causes the development of a pathological process.
has OBO namespace: chebi_ontology
has related synonym: etiopathogenetic agent
has related synonym: etiopathogenetic role
id: CHEBI:52209
in subset: 3 STAR

Axiom
annotated source: aetiopathogenetic role
annotated property: hasRelatedSynonym
annotated target: etiopathogenetic agent
database_cross_reference: ChEBI

Axiom
annotated source: aetiopathogenetic role
annotated property: hasRelatedSynonym
annotated target: etiopathogenetic role
database_cross_reference: ChEBI

pharmacological role
type: Class
subclass of: biological role
definition: A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.
has OBO namespace: chebi_ontology
id: CHEBI:52210
in subset: 3 STAR

physiological role
type: Class
subclass of: biological role
has OBO namespace: chebi_ontology
id: CHEBI:52211
in subset: 1 STAR

pharmaceutical
type: Class
subclass of: application
definition: Any substance introduced into a living organism with therapeutic or diagnostic purpose.
has alternative id: CHEBI:33293
has alternative id: CHEBI:33294
has OBO namespace: chebi_ontology
has related synonym: farmaco
has related synonym: medicament
has related synonym: pharmaceuticals
id: CHEBI:52217
in subset: 3 STAR

Axiom
annotated source: pharmaceutical
annotated property: hasRelatedSynonym
annotated target: farmaco
database_cross_reference: ChEBI

Axiom
annotated source: pharmaceutical
annotated property: hasRelatedSynonym
annotated target: medicament
database_cross_reference: ChEBI

Axiom
annotated source: pharmaceutical
annotated property: hasRelatedSynonym
annotated target: pharmaceuticals
database_cross_reference: ChEBI

cyclic organic group
type: Class
subclass of: organic group
definition: An organic group that consists of a closed ring. It may be a substituent or a skeleton.
has OBO namespace: chebi_ontology
has related synonym: cyclic organic groups
id: CHEBI:52845
in subset: 3 STAR

Axiom
annotated source: cyclic organic group
annotated property: hasRelatedSynonym
annotated target: cyclic organic groups
database_cross_reference: ChEBI

epitope
type: Class
subclass of: biological role
definition: The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.
has OBO namespace: chebi_ontology
has related synonym: antigenic determinant
has related synonym: epitope function
has related synonym: epitope role
id: CHEBI:53000
in subset: 3 STAR

Axiom
annotated source: epitope
annotated property: hasRelatedSynonym
annotated target: antigenic determinant
database_cross_reference: ChEBI

Axiom
annotated source: epitope
annotated property: hasRelatedSynonym
annotated target: epitope function
database_cross_reference: ChEBI

Axiom
annotated source: epitope
annotated property: hasRelatedSynonym
annotated target: epitope role
database_cross_reference: ChEBI

polyanionic macromolecule
type: Class
subclass of: ionic macromolecule
definition: A polymer carrying multiple negative charges.
has OBO namespace: chebi_ontology
has related synonym: polyanion
has related synonym: polyanions
id: CHEBI:53309
in subset: 3 STAR

Axiom
annotated source: polyanionic macromolecule
annotated property: hasRelatedSynonym
annotated target: polyanion
database_cross_reference: ChEBI

Axiom
annotated source: polyanionic macromolecule
annotated property: hasRelatedSynonym
annotated target: polyanions
database_cross_reference: SUBMITTER

ionic macromolecule
type: Class
subclass of: macromolecule
definition: A macromolecule containing ionic groups.
has OBO namespace: chebi_ontology
has related synonym: ionic polymer
has related synonym: polyionic macromolecule
id: CHEBI:53368
in subset: 3 STAR

Axiom
annotated source: ionic macromolecule
annotated property: hasRelatedSynonym
annotated target: ionic polymer
database_cross_reference: ChEBI

Axiom
annotated source: ionic macromolecule
annotated property: hasRelatedSynonym
annotated target: polyionic macromolecule
database_cross_reference: ChEBI

glucagon
type: Class
subclass of: peptide hormone
definition: A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.
database_cross_reference: CAS:16941-32-5
database_cross_reference: CAS:9007-92-5
database_cross_reference: DrugBank:DB00040
database_cross_reference: Drug_Central:2994
database_cross_reference: KEGG:C01501
database_cross_reference: KEGG:D00116
database_cross_reference: PMID:21940356
database_cross_reference: PMID:22014161
database_cross_reference: PMID:22154917
database_cross_reference: PMID:22166985
database_cross_reference: PMID:22167521
database_cross_reference: PMID:22214853
database_cross_reference: PMID:22227186
database_cross_reference: PMID:22286080
database_cross_reference: PMID:22294753
database_cross_reference: PMID:22318544
database_cross_reference: PMID:22334714
database_cross_reference: PMID:22399501
database_cross_reference: PMID:22438981
database_cross_reference: PMID:22454291
database_cross_reference: Reaxys:13191924
database_cross_reference: Wikipedia:Glucagon
has_exact_synonym: Glucagon
has_exact_synonym: L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine
has OBO namespace: chebi_ontology
has related synonym: Glucagone
has related synonym: HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
has related synonym: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
has related synonym: His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr
has related synonym: glucagon
has related synonym: glucagonum
id: CHEBI:5391
in subset: 3 STAR

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: CAS:16941-32-5
source: ChemIDplus

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: CAS:9007-92-5
source: ChemIDplus

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: CAS:9007-92-5
source: KEGG COMPOUND

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: Drug_Central:2994
source: DrugCentral

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:21940356
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22014161
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22154917
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22166985
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22167521
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22214853
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22227186
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22286080
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22294753
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22318544
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22334714
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22399501
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22438981
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22454291
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: Reaxys:13191924
source: Reaxys

Axiom
annotated source: glucagon
annotated property: has_exact_synonym
annotated target: Glucagon
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glucagon
annotated property: has_exact_synonym
annotated target: L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: glucagon
annotated property: hasRelatedSynonym
annotated target: Glucagone
database_cross_reference: ChemIDplus

Axiom
annotated source: glucagon
annotated property: hasRelatedSynonym
annotated target: HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
database_cross_reference: ChEBI

Axiom
annotated source: glucagon
annotated property: hasRelatedSynonym
annotated target: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
database_cross_reference: ChEBI

Axiom
annotated source: glucagon
annotated property: hasRelatedSynonym
annotated target: His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr
database_cross_reference: ChemIDplus

Axiom
annotated source: glucagon
annotated property: hasRelatedSynonym
annotated target: glucagon
database_cross_reference: ChemIDplus
has synonym type: INN

Axiom
annotated source: glucagon
annotated property: hasRelatedSynonym
annotated target: glucagonum
database_cross_reference: ChemIDplus
has synonym type: INN

heterocyclic compound
type: Class
subclass of: cyclic compound
definition: A cyclic compound having as ring members atoms of at least two different elements.
has_exact_synonym: Heterocyclic compound
has OBO namespace: chebi_ontology
has related synonym: compuesto heterociclico
has related synonym: compuestos heterociclicos
has related synonym: heterocycle
has related synonym: heterocyclic compounds
id: CHEBI:5686
in subset: 3 STAR

Axiom
annotated source: heterocyclic compound
annotated property: has_exact_synonym
annotated target: Heterocyclic compound
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: compuesto heterociclico
database_cross_reference: IUPAC

Axiom
annotated source: heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: compuestos heterociclicos
database_cross_reference: IUPAC

Axiom
annotated source: heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: heterocycle
database_cross_reference: ChEBI

Axiom
annotated source: heterocyclic compound
annotated property: hasRelatedSynonym
annotated target: heterocyclic compounds
database_cross_reference: ChEBI

tryptaminium
type: Class
subclass of: independent continuant
subclass of: primary ammonium ion
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tryptamine
definition: An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3.
database_cross_reference: Gmelin:533978
has_exact_synonym: 2-(1H-indol-3-yl)ethanaminium
has OBO namespace: chebi_ontology
has related synonym: tryptamine
has related synonym: tryptaminium cation
has related synonym: tryptaminium(1+)
id: CHEBI:57887
in subset: 3 STAR

Axiom
annotated source: tryptaminium
annotated property: database_cross_reference
annotated target: Gmelin:533978
source: Gmelin

Axiom
annotated source: tryptaminium
annotated property: has_exact_synonym
annotated target: 2-(1H-indol-3-yl)ethanaminium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: tryptaminium
annotated property: hasRelatedSynonym
annotated target: tryptamine
database_cross_reference: UniProt

Axiom
annotated source: tryptaminium
annotated property: hasRelatedSynonym
annotated target: tryptaminium cation
database_cross_reference: ChEBI

Axiom
annotated source: tryptaminium
annotated property: hasRelatedSynonym
annotated target: tryptaminium(1+)
database_cross_reference: ChEBI

bilirubin(2-)
type: Class
subclass of: independent continuant
subclass of: dicarboxylic acid dianion
subclass of: linear tetrapyrrole anion
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: bilirubin IXalpha
definition: A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3.
database_cross_reference: Beilstein:4083310
has OBO namespace: chebi_ontology
has related synonym: (4Z,15Z)-bilirubin IXalpha
has related synonym: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate
has related synonym: bilirubin dianion
id: CHEBI:57977
in subset: 3 STAR

Axiom
annotated source: bilirubin(2-)
annotated property: database_cross_reference
annotated target: Beilstein:4083310
source: Beilstein

Axiom
annotated source: bilirubin(2-)
annotated property: hasRelatedSynonym
annotated target: (4Z,15Z)-bilirubin IXalpha
database_cross_reference: UniProt

Axiom
annotated source: bilirubin(2-)
annotated property: hasRelatedSynonym
annotated target: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate
database_cross_reference: ChEBI

Axiom
annotated source: bilirubin(2-)
annotated property: hasRelatedSynonym
annotated target: bilirubin dianion
database_cross_reference: ChEBI

cationic amino-acid residue
type: Class
subclass of: organic cationic group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: amino-acid residue
definition: An amino-acid residue protonated on nitrogen.
has OBO namespace: chebi_ontology
has related synonym: amino acid cation residue
has related synonym: amino acid cation residues
has related synonym: amino-acid cation residue
has related synonym: amino-acid cation residues
has related synonym: cationic amino acid residue
has related synonym: cationic amino acid residues
has related synonym: cationic amino-acid residues
id: CHEBI:58942
in subset: 3 STAR

Axiom
annotated source: cationic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino acid cation residue
database_cross_reference: ChEBI

Axiom
annotated source: cationic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino acid cation residues
database_cross_reference: ChEBI

Axiom
annotated source: cationic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino-acid cation residue
database_cross_reference: ChEBI

Axiom
annotated source: cationic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino-acid cation residues
database_cross_reference: ChEBI

Axiom
annotated source: cationic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: cationic amino acid residue
database_cross_reference: ChEBI

Axiom
annotated source: cationic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: cationic amino acid residues
database_cross_reference: ChEBI

Axiom
annotated source: cationic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: cationic amino-acid residues
database_cross_reference: ChEBI

organosulfate oxoanion
type: Class
subclass of: organic anion
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: has functional parent
  some values from: sulfate
subclass of: Restriction
  on property: is conjugate base of
  some values from: organic sulfate
definition: An organic anion of general formula RS(=O)2O(-) where R is an organyl group.
has OBO namespace: chebi_ontology
has related synonym: organosulfate oxoanions
id: CHEBI:58958
in subset: 3 STAR

Axiom
annotated source: organosulfate oxoanion
annotated property: hasRelatedSynonym
annotated target: organosulfate oxoanions
database_cross_reference: ChEBI

linear tetrapyrrole anion
type: Class
subclass of: organic anion
definition: An organic anion arising from deprotonation of a acyclic tetrapyrrole compound.
has OBO namespace: chebi_ontology
has related synonym: acyclic tetrapyrrole anion
has related synonym: acyclic tetrapyrrole anions
has related synonym: linear tetrapyrrole anions
id: CHEBI:59252
in subset: 3 STAR

Axiom
annotated source: linear tetrapyrrole anion
annotated property: hasRelatedSynonym
annotated target: acyclic tetrapyrrole anion
database_cross_reference: ChEBI

Axiom
annotated source: linear tetrapyrrole anion
annotated property: hasRelatedSynonym
annotated target: acyclic tetrapyrrole anions
database_cross_reference: ChEBI

Axiom
annotated source: linear tetrapyrrole anion
annotated property: hasRelatedSynonym
annotated target: linear tetrapyrrole anions
database_cross_reference: ChEBI

nucleophilic reagent
type: Class
subclass of: reagent
subclass of: Lewis base
definition: A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.
has OBO namespace: chebi_ontology
has related synonym: nucleophile
has related synonym: nucleophiles
has related synonym: nucleophilic reagents
id: CHEBI:59740
in subset: 3 STAR

Axiom
annotated source: nucleophilic reagent
annotated property: hasRelatedSynonym
annotated target: nucleophile
database_cross_reference: ChEBI

Axiom
annotated source: nucleophilic reagent
annotated property: hasRelatedSynonym
annotated target: nucleophiles
database_cross_reference: ChEBI

Axiom
annotated source: nucleophilic reagent
annotated property: hasRelatedSynonym
annotated target: nucleophilic reagents
database_cross_reference: ChEBI

chemical substance
type: Class
subclass of: chemical entity
definition: A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types.
has OBO namespace: chebi_ontology
has related synonym: Chemische Substanz
id: CHEBI:59999
in subset: 3 STAR

Axiom
annotated source: chemical substance
annotated property: hasRelatedSynonym
annotated target: Chemische Substanz
database_cross_reference: ChEBI

mixture
type: Class
subclass of: chemical substance
definition: A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind.
has OBO namespace: chebi_ontology
has related synonym: Mischung
id: CHEBI:60004
in subset: 3 STAR

Axiom
annotated source: mixture
annotated property: hasRelatedSynonym
annotated target: Mischung
database_cross_reference: ChEBI

polymer
type: Class
subclass of: mixture
subclass of: Restriction
  on property: has part
  some values from: macromolecule
definition: A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc..
database_cross_reference: Wikipedia:Polymer
has_exact_synonym: Polymer
has OBO namespace: chebi_ontology
has related synonym: Kunststoff
id: CHEBI:60027
in subset: 3 STAR

Axiom
annotated source: polymer
annotated property: has_exact_synonym
annotated target: Polymer
database_cross_reference: ChEBI

Axiom
annotated source: polymer
annotated property: hasRelatedSynonym
annotated target: Kunststoff
database_cross_reference: ChEBI

ionic polymer
type: Class
subclass of: polymer
subclass of: Restriction
  on property: has part
  some values from: ionic macromolecule
definition: An ionic polymer is a polymer, composed of ionic macromolecules.
has OBO namespace: chebi_ontology
has related synonym: polyionic polymer
id: CHEBI:60164
in subset: 3 STAR

Axiom
annotated source: ionic polymer
annotated property: hasRelatedSynonym
annotated target: polyionic polymer
database_cross_reference: ChEBI

monovalent inorganic cation
type: Class
subclass of: inorganic cation
definition: An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one.
has OBO namespace: chebi_ontology
has related synonym: a monovalent cation
id: CHEBI:60242
in subset: 3 STAR

Axiom
annotated source: monovalent inorganic cation
annotated property: hasRelatedSynonym
annotated target: a monovalent cation
database_cross_reference: UniProt

peptide zwitterion
type: Class
subclass of: zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: peptide
definition: Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged.
has OBO namespace: chebi_ontology
has related synonym: a peptide
has related synonym: peptide zwitterions
id: CHEBI:60466
in subset: 3 STAR

Axiom
annotated source: peptide zwitterion
annotated property: hasRelatedSynonym
annotated target: a peptide
database_cross_reference: UniProt

Axiom
annotated source: peptide zwitterion
annotated property: hasRelatedSynonym
annotated target: peptide zwitterions
database_cross_reference: ChEBI

nucleobase-containing molecular entity
type: Class
subclass of: heteroarene
subclass of: nitrogen molecular entity
subclass of: Restriction
  on property: has functional parent
  some values from: nucleobase
definition: Any compound that has a nucleobase as a part.
has OBO namespace: chebi_ontology
has related synonym: nucleobase-containing compound
has related synonym: nucleobase-containing compounds
has related synonym: nucleobase-containing molecular entities
id: CHEBI:61120
in subset: 3 STAR

Axiom
annotated source: nucleobase-containing molecular entity
annotated property: hasRelatedSynonym
annotated target: nucleobase-containing compound
database_cross_reference: SUBMITTER

Axiom
annotated source: nucleobase-containing molecular entity
annotated property: hasRelatedSynonym
annotated target: nucleobase-containing compounds
database_cross_reference: ChEBI

Axiom
annotated source: nucleobase-containing molecular entity
annotated property: hasRelatedSynonym
annotated target: nucleobase-containing molecular entities
database_cross_reference: ChEBI

polyanionic polymer
type: Class
subclass of: ionic polymer
subclass of: Restriction
  on property: has part
  some values from: polyanionic macromolecule
definition: A polymer, composed of polyanion macromolecules.
has OBO namespace: chebi_ontology
has related synonym: polyanion
has related synonym: polyanions
id: CHEBI:61469
in subset: 3 STAR

Axiom
annotated source: polyanionic polymer
annotated property: hasRelatedSynonym
annotated target: polyanion
database_cross_reference: ChEBI

Axiom
annotated source: polyanionic polymer
annotated property: hasRelatedSynonym
annotated target: polyanions
database_cross_reference: ChEBI

oxidising agent
type: Class
subclass of: chemical role
definition: A substance that removes electrons from another reactant in a redox reaction.
has OBO namespace: chebi_ontology
has related synonym: oxidant
has related synonym: oxidants
has related synonym: oxidiser
has related synonym: oxidisers
has related synonym: oxidising agents
has related synonym: oxidizer
has related synonym: oxidizers
has related synonym: oxidizing agent
has related synonym: oxidizing agents
id: CHEBI:63248
in subset: 3 STAR

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidant
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidants
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidiser
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidisers
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidising agents
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidizer
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidizers
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidizing agent
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: hasRelatedSynonym
annotated target: oxidizing agents
database_cross_reference: ChEBI

carbohydrate derivative
type: Class
subclass of: carbohydrates and carbohydrate derivatives
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate
definition: Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds.
has OBO namespace: chebi_ontology
has related synonym: carbohydrate derivatives
has related synonym: derivatised carbohydrate
has related synonym: derivatised carbohydrates
has related synonym: derivatized carbohydrate
has related synonym: derivatized carbohydrates
id: CHEBI:63299
in subset: 3 STAR

Axiom
annotated source: carbohydrate derivative
annotated property: hasRelatedSynonym
annotated target: carbohydrate derivatives
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: hasRelatedSynonym
annotated target: derivatised carbohydrate
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: hasRelatedSynonym
annotated target: derivatised carbohydrates
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: hasRelatedSynonym
annotated target: derivatized carbohydrate
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: hasRelatedSynonym
annotated target: derivatized carbohydrates
database_cross_reference: ChEBI

carbohydrate acid derivative
type: Class
subclass of: carbohydrate derivative
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbohydrate acid derivative anion
definition: A carbohydrate derivative that is formally obtained from a carbohydrate acid.
has OBO namespace: chebi_ontology
has related synonym: carbohydrate acid derivatives
id: CHEBI:63436
in subset: 3 STAR

Axiom
annotated source: carbohydrate acid derivative
annotated property: hasRelatedSynonym
annotated target: carbohydrate acid derivatives
database_cross_reference: ChEBI

monoamine
type: Class
subclass of: aralkylamino compound
definition: An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.
database_cross_reference: PMID:21822758
database_cross_reference: PMID:21993877
database_cross_reference: PMID:22005599
database_cross_reference: PMID:22082101
database_cross_reference: PMID:22153577
database_cross_reference: PMID:22213370
database_cross_reference: PMID:22218931
database_cross_reference: PMID:22342987
database_cross_reference: PMID:22371656
has OBO namespace: chebi_ontology
has related synonym: monoamines
has related synonym: naturally occurring monoamine
has related synonym: naturally occurring monoamines
id: CHEBI:63534
in subset: 3 STAR

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:21822758
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:21993877
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22005599
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22082101
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22153577
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22213370
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22218931
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22342987
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22371656
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: hasRelatedSynonym
annotated target: monoamines
database_cross_reference: ChEBI

Axiom
annotated source: monoamine
annotated property: hasRelatedSynonym
annotated target: naturally occurring monoamine
database_cross_reference: ChEBI

Axiom
annotated source: monoamine
annotated property: hasRelatedSynonym
annotated target: naturally occurring monoamines
database_cross_reference: ChEBI

carbohydrate acid derivative anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbohydrate acid derivative
definition: A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative.
has OBO namespace: chebi_ontology
has related synonym: carbohydrate acid anion derivative
has related synonym: carbohydrate acid anion derivatives
has related synonym: carbohydrate acid derivative anions
id: CHEBI:63551
in subset: 3 STAR

Axiom
annotated source: carbohydrate acid derivative anion
annotated property: hasRelatedSynonym
annotated target: carbohydrate acid anion derivative
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid derivative anion
annotated property: hasRelatedSynonym
annotated target: carbohydrate acid anion derivatives
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid derivative anion
annotated property: hasRelatedSynonym
annotated target: carbohydrate acid derivative anions
database_cross_reference: ChEBI

food additive
type: Class
subclass of: application
subclass of: food component
definition: Any substance which is added to food to preserve or enhance its flavour and/or appearance.
database_cross_reference: Wikipedia:Food_additive
has OBO namespace: chebi_ontology
has related synonym: food additives
id: CHEBI:64047
in subset: 3 STAR

Axiom
annotated source: food additive
annotated property: hasRelatedSynonym
annotated target: food additives
database_cross_reference: ChEBI

food acidity regulator
type: Class
subclass of: food additive
definition: A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.
database_cross_reference: Wikipedia:Acidity_regulator
has OBO namespace: chebi_ontology
has related synonym: acidity regulator
has related synonym: acidity regulators
has related synonym: food acidity regulators
has related synonym: pH control agent
has related synonym: pH control agents
id: CHEBI:64049
in subset: 3 STAR

Axiom
annotated source: food acidity regulator
annotated property: hasRelatedSynonym
annotated target: acidity regulator
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: hasRelatedSynonym
annotated target: acidity regulators
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: hasRelatedSynonym
annotated target: food acidity regulators
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: hasRelatedSynonym
annotated target: pH control agent
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: hasRelatedSynonym
annotated target: pH control agents
database_cross_reference: ChEBI

aralkylamino compound
type: Class
subclass of: organic amino compound
definition: An organic amino compound in which an aminoalkyl group is linked to an arene.
has OBO namespace: chebi_ontology
has related synonym: aralkylamino compounds
id: CHEBI:64365
in subset: 3 STAR

Axiom
annotated source: aralkylamino compound
annotated property: hasRelatedSynonym
annotated target: aralkylamino compounds
database_cross_reference: ChEBI

somatostatin
type: Class
subclass of: heterodetic cyclic peptide
subclass of: peptide hormone
definition: A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14.
database_cross_reference: CAS:38916-34-6
database_cross_reference: Drug_Central:2997
database_cross_reference: HMDB:HMDB0013072
database_cross_reference: KEGG:C16022
database_cross_reference: KEGG:D07431
database_cross_reference: LINCS:LSM-5326
database_cross_reference: PMID:21922516
database_cross_reference: PMID:22129035
database_cross_reference: PMID:22147011
database_cross_reference: PMID:22251942
database_cross_reference: PMID:22483686
database_cross_reference: PMID:22509294
database_cross_reference: Reaxys:10148626
database_cross_reference: Wikipedia:Somatostatin
has_exact_synonym: L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
has OBO namespace: chebi_ontology
has related synonym: Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]
has related synonym: L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide
has related synonym: Somatostatin-1
has related synonym: Somatostatin-14
has related synonym: Synthetic growth hormone release-inhibiting hormone
has related synonym: somatostatin
has related synonym: somatostatina
has related synonym: somatostatine
has related synonym: somatostatinum
id: CHEBI:64628
in subset: 3 STAR

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: CAS:38916-34-6
source: ChemIDplus

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: CAS:38916-34-6
source: KEGG DRUG

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: Drug_Central:2997
source: DrugCentral

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:21922516
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22129035
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22147011
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22251942
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22483686
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22509294
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: Reaxys:10148626
source: Reaxys

Axiom
annotated source: somatostatin
annotated property: has_exact_synonym
annotated target: L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]
database_cross_reference: ChEBI

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide
database_cross_reference: ChemIDplus

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: Somatostatin-1
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: Somatostatin-14
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: Synthetic growth hormone release-inhibiting hormone
database_cross_reference: ChemIDplus

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: somatostatin
database_cross_reference: KEGG_DRUG
has synonym type: INN

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: somatostatina
database_cross_reference: ChemIDplus
has synonym type: INN

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: somatostatine
database_cross_reference: ChemIDplus
has synonym type: INN

Axiom
annotated source: somatostatin
annotated property: hasRelatedSynonym
annotated target: somatostatinum
database_cross_reference: ChemIDplus
has synonym type: INN

one-carbon compound
type: Class
subclass of: organic molecular entity
definition: An organic molecular entity containing a single carbon atom (C1).
has OBO namespace: chebi_ontology
has related synonym: one-carbon compounds
id: CHEBI:64708
in subset: 3 STAR

Axiom
annotated source: one-carbon compound
annotated property: hasRelatedSynonym
annotated target: one-carbon compounds
database_cross_reference: ChEBI

organic acid
type: Class
subclass of: organic molecular entity
definition: Any organic molecular entity that is acidic and contains carbon in covalent linkage.
has OBO namespace: chebi_ontology
has related synonym: organic acids
id: CHEBI:64709
in subset: 3 STAR

Axiom
annotated source: organic acid
annotated property: hasRelatedSynonym
annotated target: organic acids
database_cross_reference: ChEBI

cationic group
type: Class
subclass of: group
definition: A group that carries an overall positive charge.
has OBO namespace: chebi_ontology
has related synonym: cationic groups
id: CHEBI:64766
in subset: 3 STAR

Axiom
annotated source: cationic group
annotated property: hasRelatedSynonym
annotated target: cationic groups
database_cross_reference: ChEBI

anionic group
type: Class
subclass of: group
definition: A group that carries an overall negative charge.
has OBO namespace: chebi_ontology
has related synonym: anionic groups
id: CHEBI:64767
in subset: 3 STAR

Axiom
annotated source: anionic group
annotated property: hasRelatedSynonym
annotated target: anionic groups
database_cross_reference: ChEBI

organic cationic group
type: Class
subclass of: cationic group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: organic group
definition: A cationic group that contains carbon.
has OBO namespace: chebi_ontology
has related synonym: organic cationic groups
id: CHEBI:64769
in subset: 3 STAR

Axiom
annotated source: organic cationic group
annotated property: hasRelatedSynonym
annotated target: organic cationic groups
database_cross_reference: ChEBI

organic anionic group
type: Class
subclass of: anionic group
subclass of: Restriction
  on property: is conjugate base of
  some values from: organic group
definition: An anionic group that contains carbon.
has OBO namespace: chebi_ontology
has related synonym: organic anionic groups
id: CHEBI:64775
in subset: 3 STAR

Axiom
annotated source: organic anionic group
annotated property: hasRelatedSynonym
annotated target: organic anionic groups
database_cross_reference: ChEBI

anionic amino-acid residue
type: Class
subclass of: organic anionic group
subclass of: Restriction
  on property: is conjugate base of
  some values from: amino-acid residue
definition: An amino-acid residue carrying an overall negative charge.
has OBO namespace: chebi_ontology
has related synonym: amino acid anion residue
has related synonym: amino acid anion residues
has related synonym: amino-acid anion residue
has related synonym: amino-acid anion residues
has related synonym: anionic amino acid residue
has related synonym: anionic amino acid residues
id: CHEBI:64898
in subset: 3 STAR

Axiom
annotated source: anionic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino acid anion residue
database_cross_reference: ChEBI

Axiom
annotated source: anionic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino acid anion residues
database_cross_reference: ChEBI

Axiom
annotated source: anionic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino-acid anion residue
database_cross_reference: ChEBI

Axiom
annotated source: anionic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: amino-acid anion residues
database_cross_reference: ChEBI

Axiom
annotated source: anionic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: anionic amino acid residue
database_cross_reference: ChEBI

Axiom
annotated source: anionic amino-acid residue
annotated property: hasRelatedSynonym
annotated target: anionic amino acid residues
database_cross_reference: ChEBI

poison
type: Class
subclass of: biological role
definition: Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
database_cross_reference: Wikipedia:Poison
has OBO namespace: chebi_ontology
has related synonym: poisonous agent
has related synonym: poisonous agents
has related synonym: poisonous substance
has related synonym: poisonous substances
has related synonym: poisons
has related synonym: toxic agent
has related synonym: toxic agents
has related synonym: toxic substance
has related synonym: toxic substances
id: CHEBI:64909
in subset: 3 STAR

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: poisonous agent
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: poisonous agents
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: poisonous substance
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: poisonous substances
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: poisons
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: toxic agent
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: toxic agents
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: toxic substance
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: hasRelatedSynonym
annotated target: toxic substances
database_cross_reference: ChEBI

polysaccharide derivative
type: Class
subclass of: glycan
subclass of: biomacromolecule
subclass of: carbohydrate derivative
subclass of: Restriction
  on property: has functional parent
  some values from: polysaccharide
definition: A carbohydrate derivative that is any derivative of a polysaccharide.
has OBO namespace: chebi_ontology
has related synonym: polysaccharide derivatives
id: CHEBI:65212
in subset: 3 STAR

Axiom
annotated source: polysaccharide derivative
annotated property: hasRelatedSynonym
annotated target: polysaccharide derivatives
database_cross_reference: ChEBI

food preservative
type: Class
subclass of: food additive
definition: Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.
has OBO namespace: chebi_ontology
has related synonym: food preservatives
id: CHEBI:65255
in subset: 3 STAR

Axiom
annotated source: food preservative
annotated property: hasRelatedSynonym
annotated target: food preservatives
database_cross_reference: ChEBI

antimicrobial food preservative
type: Class
subclass of: antimicrobial agent
subclass of: food preservative
definition: A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).
has OBO namespace: chebi_ontology
has related synonym: antimicrobial food preservatives
has related synonym: antimicrobial preservative
has related synonym: antimicrobial preservatives
id: CHEBI:65256
in subset: 3 STAR

Axiom
annotated source: antimicrobial food preservative
annotated property: hasRelatedSynonym
annotated target: antimicrobial food preservatives
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial food preservative
annotated property: hasRelatedSynonym
annotated target: antimicrobial preservative
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial food preservative
annotated property: hasRelatedSynonym
annotated target: antimicrobial preservatives
database_cross_reference: ChEBI

primary ammonium ion
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: primary amino compound
definition: An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3.
has OBO namespace: chebi_ontology
has related synonym: a primary amine
has related synonym: substituted ammonium
id: CHEBI:65296
in subset: 3 STAR

Axiom
annotated source: primary ammonium ion
annotated property: hasRelatedSynonym
annotated target: a primary amine
database_cross_reference: UniProt

Axiom
annotated source: primary ammonium ion
annotated property: hasRelatedSynonym
annotated target: substituted ammonium
database_cross_reference: ChEBI

anti-inflammatory agent
type: Class
subclass of: application
definition: Any compound that has anti-inflammatory effects.
has OBO namespace: chebi_ontology
has related synonym: anti-inflammatory agents
has related synonym: antiinflammatory agent
has related synonym: antiinflammatory agents
id: CHEBI:67079
in subset: 3 STAR

Axiom
annotated source: anti-inflammatory agent
annotated property: hasRelatedSynonym
annotated target: anti-inflammatory agents
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory agent
annotated property: hasRelatedSynonym
annotated target: antiinflammatory agent
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory agent
annotated property: hasRelatedSynonym
annotated target: antiinflammatory agents
database_cross_reference: ChEBI

(R)-noradrenaline(1+)
type: Class
subclass of: independent continuant
subclass of: noradrenaline(1+)
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: (R)-noradrenaline
definition: An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3.
database_cross_reference: PDBeChem:E5E
has_exact_synonym: (2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium
has OBO namespace: chebi_ontology
has related synonym: (R)-noradrenaline
has related synonym: (R)-noradrenaline cation
has related synonym: (R)-noradrenalinium cation
has related synonym: (R)-noradrenalinium(1+)
id: CHEBI:72587
in subset: 3 STAR

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: has_exact_synonym
annotated target: (2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium
database_cross_reference: IUPAC
has synonym type: IUPAC NAME

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: hasRelatedSynonym
annotated target: (R)-noradrenaline
database_cross_reference: UniProt

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: hasRelatedSynonym
annotated target: (R)-noradrenaline cation
database_cross_reference: ChEBI

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: hasRelatedSynonym
annotated target: (R)-noradrenalinium cation
database_cross_reference: ChEBI

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: hasRelatedSynonym
annotated target: (R)-noradrenalinium(1+)
database_cross_reference: ChEBI

organic molecule
type: Class
subclass of: molecule
subclass of: organic molecular entity
definition: Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.
has OBO namespace: chebi_ontology
has related synonym: organic compound
has related synonym: organic compounds
has related synonym: organic molecules
id: CHEBI:72695
in subset: 3 STAR

Axiom
annotated source: organic molecule
annotated property: hasRelatedSynonym
annotated target: organic compound
database_cross_reference: ChEBI

Axiom
annotated source: organic molecule
annotated property: hasRelatedSynonym
annotated target: organic compounds
database_cross_reference: ChEBI

Axiom
annotated source: organic molecule
annotated property: hasRelatedSynonym
annotated target: organic molecules
database_cross_reference: ChEBI

exopolysaccharide
type: Class
subclass of: biomacromolecule
definition: A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment.
database_cross_reference: MetaCyc:Exopolysaccharides
database_cross_reference: PMID:11160795
database_cross_reference: PMID:11785425
database_cross_reference: PMID:1444258
database_cross_reference: PMID:15738217
database_cross_reference: PMID:16075348
database_cross_reference: PMID:17440912
database_cross_reference: PMID:18097339
database_cross_reference: PMID:19453747
database_cross_reference: PMID:20172021
database_cross_reference: PMID:20631870
database_cross_reference: PMID:20718297
database_cross_reference: PMID:2688547
database_cross_reference: PMID:6354590
database_cross_reference: Wikipedia:Exopolysaccharide
database_cross_reference: Wikipedia:Extracellular_polymeric_substance
has OBO namespace: chebi_ontology
has related synonym: exopolysaccharides
has related synonym: extracellular polymeric substance
has related synonym: extracellular polymeric substances
id: CHEBI:72813
in subset: 3 STAR

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:11160795
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:11785425
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:1444258
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:15738217
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:16075348
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:17440912
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:18097339
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:19453747
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:20172021
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:20631870
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:20718297
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:2688547
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:6354590
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: hasRelatedSynonym
annotated target: exopolysaccharides
database_cross_reference: ChEBI

Axiom
annotated source: exopolysaccharide
annotated property: hasRelatedSynonym
annotated target: extracellular polymeric substance
database_cross_reference: ChEBI

Axiom
annotated source: exopolysaccharide
annotated property: hasRelatedSynonym
annotated target: extracellular polymeric substances
database_cross_reference: ChEBI

indole skeleton
type: Class
subclass of: organic heterobicyclic ring
definition: A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring.
has OBO namespace: chebi_ontology
id: CHEBI:73398
in subset: 3 STAR

organic heterobicyclic ring
type: Class
subclass of: cyclic organic group
definition: A bicyclic organic group that contains both carbon and hetero atoms.
has OBO namespace: chebi_ontology
has related synonym: organic heterobicyclic rings
id: CHEBI:73541
in subset: 3 STAR

Axiom
annotated source: organic heterobicyclic ring
annotated property: hasRelatedSynonym
annotated target: organic heterobicyclic rings
database_cross_reference: ChEBI

eukaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
has OBO namespace: chebi_ontology
has related synonym: eukaryotic metabolites
id: CHEBI:75763
in subset: 3 STAR

Axiom
annotated source: eukaryotic metabolite
annotated property: hasRelatedSynonym
annotated target: eukaryotic metabolites
database_cross_reference: ChEBI

animal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
has alternative id: CHEBI:77721
has alternative id: CHEBI:77743
has OBO namespace: chebi_ontology
has related synonym: animal metabolites
id: CHEBI:75767
in subset: 3 STAR

Axiom
annotated source: animal metabolite
annotated property: hasRelatedSynonym
annotated target: animal metabolites
database_cross_reference: ChEBI

mammalian metabolite
type: Class
subclass of: animal metabolite
definition: Any animal metabolite produced during a metabolic reaction in mammals.
has alternative id: CHEBI:77464
has alternative id: CHEBI:77744
has OBO namespace: chebi_ontology
has related synonym: mammalian metabolites
id: CHEBI:75768
in subset: 3 STAR

Axiom
annotated source: mammalian metabolite
annotated property: hasRelatedSynonym
annotated target: mammalian metabolites
database_cross_reference: ChEBI

mouse metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
has OBO namespace: chebi_ontology
has related synonym: Mus musculus metabolite
has related synonym: Mus musculus metabolites
has related synonym: mouse metabolites
id: CHEBI:75771
in subset: 3 STAR

Axiom
annotated source: mouse metabolite
annotated property: hasRelatedSynonym
annotated target: Mus musculus metabolite
database_cross_reference: ChEBI

Axiom
annotated source: mouse metabolite
annotated property: hasRelatedSynonym
annotated target: Mus musculus metabolites
database_cross_reference: ChEBI

Axiom
annotated source: mouse metabolite
annotated property: hasRelatedSynonym
annotated target: mouse metabolites
database_cross_reference: ChEBI

Saccharomyces cerevisiae metabolite
type: Class
subclass of: fungal metabolite
definition: Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
has alternative id: CHEBI:76949
has alternative id: CHEBI:76951
has OBO namespace: chebi_ontology
has related synonym: S. cerevisiae metabolite
has related synonym: S. cerevisiae metabolites
has related synonym: S. cerevisiae secondary metabolite
has related synonym: S. cerevisiae secondary metabolites
has related synonym: Saccharomyces cerevisiae metabolites
has related synonym: Saccharomyces cerevisiae secondary metabolites
has related synonym: baker's yeast metabolite
has related synonym: baker's yeast metabolites
has related synonym: baker's yeast secondary metabolite
has related synonym: baker's yeast secondary metabolites
id: CHEBI:75772
in subset: 3 STAR

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: S. cerevisiae metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: S. cerevisiae metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: S. cerevisiae secondary metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: S. cerevisiae secondary metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: Saccharomyces cerevisiae metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: Saccharomyces cerevisiae secondary metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: baker's yeast metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: baker's yeast metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: baker's yeast secondary metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: hasRelatedSynonym
annotated target: baker's yeast secondary metabolites
database_cross_reference: ChEBI

prokaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
has OBO namespace: chebi_ontology
has related synonym: prokaryotic metabolites
id: CHEBI:75787
in subset: 3 STAR

Axiom
annotated source: prokaryotic metabolite
annotated property: hasRelatedSynonym
annotated target: prokaryotic metabolites
database_cross_reference: ChEBI

xenobiotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced by metabolism of a xenobiotic compound.
has OBO namespace: chebi_ontology
has related synonym: xenobiotic metabolites
id: CHEBI:76206
in subset: 3 STAR

Axiom
annotated source: xenobiotic metabolite
annotated property: hasRelatedSynonym
annotated target: xenobiotic metabolites
database_cross_reference: ChEBI

EC 3.* (hydrolase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
database_cross_reference: Wikipedia:Hydrolase
has OBO namespace: chebi_ontology
has related synonym: EC 3.* (hydrolase) inhibitors
has related synonym: EC 3.* inhibitor
has related synonym: EC 3.* inhibitors
has related synonym: EC 3.*.*.* inhibitor
has related synonym: EC 3.*.*.* inhibitors
has related synonym: hydrolase (EC 3.*) inhibitor
has related synonym: hydrolase (EC 3.*) inhibitors
has related synonym: hydrolase inhibitor
has related synonym: hydrolase inhibitors
id: CHEBI:76759
in subset: 3 STAR

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.* (hydrolase) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.* inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.*.*.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.*.*.* inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: hydrolase (EC 3.*) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: hydrolase (EC 3.*) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: hydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: hydrolase inhibitors
database_cross_reference: ChEBI

EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
has OBO namespace: chebi_ontology
has related synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
has related synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
has related synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
has related synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
has related synonym: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
has related synonym: EC 3.5.* inhibitor
has related synonym: EC 3.5.* inhibitors
id: CHEBI:76764
in subset: 3 STAR

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.* inhibitors
database_cross_reference: ChEBI

EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
has OBO namespace: chebi_ontology
has related synonym: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
has related synonym: EC 3.5.1.* inhibitor
has related synonym: EC 3.5.1.* inhibitors
has related synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
has related synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
id: CHEBI:76807
in subset: 3 STAR

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.1.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.1.* inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: hasRelatedSynonym
annotated target: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
database_cross_reference: ChEBI

plant metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
has alternative id: CHEBI:75766
has alternative id: CHEBI:76925
has OBO namespace: chebi_ontology
has related synonym: plant metabolites
has related synonym: plant secondary metabolites
id: CHEBI:76924
in subset: 3 STAR

Axiom
annotated source: plant metabolite
annotated property: hasRelatedSynonym
annotated target: plant metabolites
database_cross_reference: ChEBI

Axiom
annotated source: plant metabolite
annotated property: hasRelatedSynonym
annotated target: plant secondary metabolites
database_cross_reference: ChEBI

fungal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
has alternative id: CHEBI:75765
has alternative id: CHEBI:76947
has OBO namespace: chebi_ontology
has related synonym: fungal metabolites
id: CHEBI:76946
in subset: 3 STAR

Axiom
annotated source: fungal metabolite
annotated property: hasRelatedSynonym
annotated target: fungal metabolites
database_cross_reference: ChEBI

human xenobiotic metabolite
type: Class
subclass of: xenobiotic metabolite
subclass of: human metabolite
definition: Any human metabolite produced by metabolism of a xenobiotic compound in humans.
has OBO namespace: chebi_ontology
has related synonym: human xenobiotic metabolites
id: CHEBI:76967
in subset: 3 STAR

Axiom
annotated source: human xenobiotic metabolite
annotated property: hasRelatedSynonym
annotated target: human xenobiotic metabolites
database_cross_reference: ChEBI

bacterial metabolite
type: Class
subclass of: prokaryotic metabolite
definition: Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
has alternative id: CHEBI:75760
has alternative id: CHEBI:76970
has OBO namespace: chebi_ontology
id: CHEBI:76969
in subset: 3 STAR

Escherichia coli metabolite
type: Class
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
has OBO namespace: chebi_ontology
has related synonym: E.coli metabolite
has related synonym: E.coli metabolites
has related synonym: Escherichia coli metabolites
id: CHEBI:76971
in subset: 3 STAR

Axiom
annotated source: Escherichia coli metabolite
annotated property: hasRelatedSynonym
annotated target: E.coli metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Escherichia coli metabolite
annotated property: hasRelatedSynonym
annotated target: E.coli metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Escherichia coli metabolite
annotated property: hasRelatedSynonym
annotated target: Escherichia coli metabolites
database_cross_reference: ChEBI

human metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
has alternative id: CHEBI:75770
has alternative id: CHEBI:77123
has OBO namespace: chebi_ontology
has related synonym: H. sapiens metabolite
has related synonym: H. sapiens metabolites
has related synonym: Homo sapiens metabolite
has related synonym: Homo sapiens metabolites
id: CHEBI:77746
in subset: 3 STAR

Axiom
annotated source: human metabolite
annotated property: hasRelatedSynonym
annotated target: H. sapiens metabolite
database_cross_reference: ChEBI

Axiom
annotated source: human metabolite
annotated property: hasRelatedSynonym
annotated target: H. sapiens metabolites
database_cross_reference: ChEBI

Axiom
annotated source: human metabolite
annotated property: hasRelatedSynonym
annotated target: Homo sapiens metabolite
database_cross_reference: ChEBI

Axiom
annotated source: human metabolite
annotated property: hasRelatedSynonym
annotated target: Homo sapiens metabolites
database_cross_reference: ChEBI

EC 3.5.1.4 (amidase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
database_cross_reference: Wikipedia:Amidase
has OBO namespace: chebi_ontology
has related synonym: EC 3.5.1.4 (amidase) inhibitors
has related synonym: EC 3.5.1.4 inhibitor
has related synonym: EC 3.5.1.4 inhibitors
has related synonym: N-acetylaminohydrolase inhibitor
has related synonym: N-acetylaminohydrolase inhibitors
has related synonym: acylamidase inhibitor
has related synonym: acylamidase inhibitors
has related synonym: acylamide amidohydrolase inhibitor
has related synonym: acylamide amidohydrolase inhibitors
has related synonym: amidase (EC 3.5.1.4) inhibitor
has related synonym: amidase (EC 3.5.1.4) inhibitors
has related synonym: amidase inhibitor
has related synonym: amidase inhibitors
has related synonym: amidohydrolase inhibitor
has related synonym: amidohydrolase inhibitors
has related synonym: deaminase inhibitor
has related synonym: deaminase inhibitors
has related synonym: fatty acylamidase inhibitor
has related synonym: fatty acylamidase inhibitors
id: CHEBI:77941
in subset: 3 STAR

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.1.4 (amidase) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.1.4 inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: EC 3.5.1.4 inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: N-acetylaminohydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: N-acetylaminohydrolase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: acylamidase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: acylamidase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: acylamide amidohydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: acylamide amidohydrolase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: amidase (EC 3.5.1.4) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: amidase (EC 3.5.1.4) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: amidase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: amidase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: amidohydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: amidohydrolase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: deaminase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: deaminase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: fatty acylamidase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: hasRelatedSynonym
annotated target: fatty acylamidase inhibitors
database_cross_reference: ChEBI

food packaging gas
type: Class
subclass of: food additive
definition: A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container.
database_cross_reference: Wikipedia:Packaging_gas
has OBO namespace: chebi_ontology
has related synonym: food packaging gases
id: CHEBI:77974
in subset: 3 STAR

Axiom
annotated source: food packaging gas
annotated property: hasRelatedSynonym
annotated target: food packaging gases
database_cross_reference: ChEBI

food component
type: Class
subclass of: physiological role
definition: A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
has OBO namespace: chebi_ontology
has related synonym: dietary component
has related synonym: dietary components
has related synonym: food components
id: CHEBI:78295
in subset: 3 STAR

Axiom
annotated source: food component
annotated property: hasRelatedSynonym
annotated target: dietary component
database_cross_reference: ChEBI

Axiom
annotated source: food component
annotated property: hasRelatedSynonym
annotated target: dietary components
database_cross_reference: ChEBI

Axiom
annotated source: food component
annotated property: hasRelatedSynonym
annotated target: food components
database_cross_reference: ChEBI

refrigerant
type: Class
subclass of: application
definition: A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
database_cross_reference: Wikipedia:Refrigerant
has OBO namespace: chebi_ontology
has related synonym: refrigerants
id: CHEBI:78433
in subset: 3 STAR

Axiom
annotated source: refrigerant
annotated property: hasRelatedSynonym
annotated target: refrigerants
database_cross_reference: ChEBI

alpha-amino-acid zwitterion
type: Class
subclass of: amino-acid zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: alpha-amino acid
definition: An amino acid-zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3.
has alternative id: CHEBI:83409
database_cross_reference: MetaCyc:Alpha-Amino-Acids
has OBO namespace: chebi_ontology
has related synonym: alpha-amino acid zwitterion
has related synonym: alpha-amino acid zwitterions
has related synonym: alpha-amino-acid zwitterions
has related synonym: an alpha-amino acid
id: CHEBI:78608
in subset: 3 STAR

Axiom
annotated source: alpha-amino-acid zwitterion
annotated property: database_cross_reference
annotated target: MetaCyc:Alpha-Amino-Acids
source: SUBMITTER

Axiom
annotated source: alpha-amino-acid zwitterion
annotated property: hasRelatedSynonym
annotated target: alpha-amino acid zwitterion
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid zwitterion
annotated property: hasRelatedSynonym
annotated target: alpha-amino acid zwitterions
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid zwitterion
annotated property: hasRelatedSynonym
annotated target: alpha-amino-acid zwitterions
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid zwitterion
annotated property: hasRelatedSynonym
annotated target: an alpha-amino acid
database_cross_reference: UniProt

carbohydrates and carbohydrate derivatives
type: Class
subclass of: organooxygen compound
definition: Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation.
has OBO namespace: chebi_ontology
has related synonym: carbohydrates and derivatives
has related synonym: carbohydrates and their derivatives
id: CHEBI:78616
in subset: 3 STAR

Axiom
annotated source: carbohydrates and carbohydrate derivatives
annotated property: hasRelatedSynonym
annotated target: carbohydrates and derivatives
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrates and carbohydrate derivatives
annotated property: hasRelatedSynonym
annotated target: carbohydrates and their derivatives
database_cross_reference: ChEBI

fundamental metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced by all living cells.
has OBO namespace: chebi_ontology
has related synonym: essential metabolite
has related synonym: essential metabolites
has related synonym: fundamental metabolites
id: CHEBI:78675
in subset: 3 STAR

Axiom
annotated source: fundamental metabolite
annotated property: hasRelatedSynonym
annotated target: essential metabolite
database_cross_reference: ChEBI

Axiom
annotated source: fundamental metabolite
annotated property: hasRelatedSynonym
annotated target: essential metabolites
database_cross_reference: ChEBI

Axiom
annotated source: fundamental metabolite
annotated property: hasRelatedSynonym
annotated target: fundamental metabolites
database_cross_reference: ChEBI

divalent inorganic anion
type: Class
subclass of: inorganic anion
definition: Any inorganic anion with a valency of two.
has OBO namespace: chebi_ontology
has related synonym: divalent inorganic anions
id: CHEBI:79388
in subset: 3 STAR

Axiom
annotated source: divalent inorganic anion
annotated property: hasRelatedSynonym
annotated target: divalent inorganic anions
database_cross_reference: ChEBI

monovalent inorganic anion
type: Class
subclass of: inorganic anion
definition: Any inorganic anion with a valency of one.
has OBO namespace: chebi_ontology
has related synonym: monovalent inorganic anions
id: CHEBI:79389
in subset: 3 STAR

Axiom
annotated source: monovalent inorganic anion
annotated property: hasRelatedSynonym
annotated target: monovalent inorganic anions
database_cross_reference: ChEBI

crustacean metabolite
type: Class
subclass of: animal metabolite
definition: An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
has OBO namespace: chebi_ontology
has related synonym: crustacean metabolites
id: CHEBI:83039
in subset: 3 STAR

Axiom
annotated source: crustacean metabolite
annotated property: hasRelatedSynonym
annotated target: crustacean metabolites
database_cross_reference: ChEBI

Daphnia magna metabolite
type: Class
subclass of: Daphnia metabolite
definition: A Daphnia metabolite produced by the species Daphnia magna.
has OBO namespace: chebi_ontology
has related synonym: Daphnia magna metabolites
id: CHEBI:83056
in subset: 3 STAR

Axiom
annotated source: Daphnia magna metabolite
annotated property: hasRelatedSynonym
annotated target: Daphnia magna metabolites
database_cross_reference: ChEBI

Daphnia metabolite
type: Class
subclass of: crustacean metabolite
definition: A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
database_cross_reference: Wikipedia:Daphnia
has OBO namespace: chebi_ontology
has related synonym: Daphnia metabolites
id: CHEBI:83057
in subset: 3 STAR

Axiom
annotated source: Daphnia metabolite
annotated property: hasRelatedSynonym
annotated target: Daphnia metabolites
database_cross_reference: ChEBI

hydroxyindoles
type: Class
subclass of: indoles
subclass of: organic hydroxy compound
definition: Any member of the class of indoles carrying at least one hydroxy group.
has OBO namespace: chebi_ontology
id: CHEBI:84729
in subset: 3 STAR

cell
type: Class
subclass of: UBERON_0000061
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon_131567
disjoint with: GO_0031012
disjoint with: GO_0032991
disjoint with: GO_0043226
definition: A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CALOHA:TS-2035
database_cross_reference: FMA:68646
database_cross_reference: GO:0005623
database_cross_reference: KUPO:0000002
database_cross_reference: MESH:D002477
database_cross_reference: VHOG:0001533
database_cross_reference: WBbt:0004017
database_cross_reference: XAO:0003012
in subset: cellxgene subset
in subset: upper level
comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).

Axiom
annotated source: cell
annotated property: definition
annotated target: A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CARO:mah

neural crest derived fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: develops from
    some values from: migratory neural crest cell
subclass of: fibroblast
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
definition: Any fibroblast that is derived from the neural crest.
has_exact_synonym: fibroblast neural crest derived

Axiom
annotated source: neural crest derived fibroblast
annotated property: definition
annotated target: Any fibroblast that is derived from the neural crest.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

neuronal receptor cell
type: Class
equivalent class: Class
  intersection of: sensory receptor cell
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: sensory neuron
subclass of: sensory receptor cell
definition: Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception.
has_exact_synonym: neuronal receptor cell (sensu Animalia)
in subset: cellxgene subset

Axiom
annotated source: neuronal receptor cell
annotated property: definition
annotated target: Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception.
database_cross_reference: FBC:Autogenerated

early embryonic cell (metazoa)
type: Class
subclass of: embryonic cell (metazoa)
definition: A cell found in the embryo before the formation of all the gem layers is complete.

Axiom
annotated source: early embryonic cell (metazoa)
annotated property: definition
annotated target: A cell found in the embryo before the formation of all the gem layers is complete.
database_cross_reference: GOC:tfm

migratory cranial neural crest cell
type: Class
subclass of: migratory neural crest cell
definition: Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination.

Axiom
annotated source: migratory cranial neural crest cell
annotated property: definition
annotated target: Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination.
database_cross_reference: ZFA:0007091
database_cross_reference: https://orcid.org/0000-0001-5208-3432

migratory trunk neural crest cell
type: Class
subclass of: migratory neural crest cell
definition: Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination.

Axiom
annotated source: migratory trunk neural crest cell
annotated property: definition
annotated target: Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination.
database_cross_reference: ZFA:0007095
database_cross_reference: https://orcid.org/0000-0001-5208-3432

germ line stem cell
type: Class
equivalent class: Class
  intersection of: germ line cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: stem cell
subclass of: germ line cell
definition: A stem cell that is the precursor of gametes.
has_exact_synonym: germline stem cell

Axiom
annotated source: germ line stem cell
annotated property: subClassOf
annotated target: stem cell
is inferred: true

Axiom
annotated source: germ line stem cell
annotated property: definition
annotated target: A stem cell that is the precursor of gametes.
database_cross_reference: doi:10.1016/j.stem.2012.05.016

female germ cell
type: Class
equivalent class: Class
  intersection of: germ cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048477
subclass of: eukaryotic cell
subclass of: germ cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0048477
definition: Female germ cell is a germ cell that supports female gamete production.
database_cross_reference: MA:0000388
database_cross_reference: VHOG:0001530
database_cross_reference: ncithesaurus:Egg
in subset: cellxgene subset

Axiom
annotated source: female germ cell
annotated property: subClassOf
annotated target: germ cell
is inferred: true

Axiom
annotated source: female germ cell
annotated property: definition
annotated target: Female germ cell is a germ cell that supports female gamete production.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:11023867
database_cross_reference: PMID:20454446

female germ line stem cell
type: Class
equivalent class: Class
  intersection of: female germ cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: germ line stem cell
subclass of: female germ cell
definition: A stem cell that is the precursor of female gametes.

Axiom
annotated source: female germ line stem cell
annotated property: subClassOf
annotated target: germ line stem cell
is inferred: true

Axiom
annotated source: female germ line stem cell
annotated property: subClassOf
annotated target: female germ cell
is inferred: true

Axiom
annotated source: female germ line stem cell
annotated property: definition
annotated target: A stem cell that is the precursor of female gametes.
database_cross_reference: doi:10.1016/j.stem.2012.05.016

oocyte
type: Class
subclass of: female germ cell
subclass of: Restriction
  on property: participates in
  some values from: GO_0007143
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon_33208
definition: A female germ cell that has entered meiosis.
database_cross_reference: BTO:0000964
database_cross_reference: CALOHA:TS-0711
database_cross_reference: FMA:18644
database_cross_reference: MESH:D009865
database_cross_reference: WBbt:0006797
has related synonym: oogonium
in subset: cellxgene subset

Axiom
annotated source: oocyte
annotated property: subClassOf
annotated target: female germ cell
is inferred: true

Axiom
annotated source: oocyte
annotated property: definition
annotated target: A female germ cell that has entered meiosis.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

oogonial cell
type: Class
equivalent class: Class
  intersection of: female germ cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0000278
subclass of: female germ cell
subclass of: Restriction
  on property: develops from
  some values from: primordial germ cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0000278
definition: An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.
database_cross_reference: FMA:83673
in subset: cellxgene subset

Axiom
annotated source: oogonial cell
annotated property: subClassOf
annotated target: female germ cell
is inferred: true

Axiom
annotated source: oogonial cell
annotated property: definition
annotated target: An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

egg cell
type: Class
subclass of: female gamete
subclass of: Restriction
  on property: participates in
  some values from: GO_0007143
subclass of: Restriction
  on property: develops from
  some values from: oocyte
definition: A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.
database_cross_reference: BTO:0000369
database_cross_reference: BTO:0003801
database_cross_reference: CALOHA:TS-2191
database_cross_reference: FMA:67343
database_cross_reference: MESH:D010063
has_exact_synonym: mature oocyte
has_exact_synonym: ovum

Axiom
annotated source: egg cell
annotated property: subClassOf
annotated target: female gamete
is inferred: true

Axiom
annotated source: egg cell
annotated property: definition
annotated target: A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

smooth muscle cell neural crest derived
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: develops from
    some values from: migratory neural crest cell
subclass of: smooth muscle cell
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
definition: A smooth muscle cell derived from the neural crest.

Axiom
annotated source: smooth muscle cell neural crest derived
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: smooth muscle cell neural crest derived
annotated property: definition
annotated target: A smooth muscle cell derived from the neural crest.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

neural crest derived neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: develops from
    some values from: migratory neural crest cell
subclass of: neuron
subclass of: Restriction
  on property: develops from
  some values from: neural crest derived neuroblast
definition: Any neuron that develops from some migratory neural crest cell.
has_exact_synonym: neuron neural crest derived

Axiom
annotated source: neural crest derived neuron
annotated property: subClassOf
annotated target: neuron
is inferred: true

Axiom
annotated source: neural crest derived neuron
annotated property: definition
annotated target: Any neuron that develops from some migratory neural crest cell.
database_cross_reference: FBC:Autogenerated

neuroblast (sensu Vertebrata)
type: Class
subclass of: non-terminally differentiated cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon 7742
definition: A cell that will develop into a neuron often after a migration phase.
database_cross_reference: BTO:0000930
database_cross_reference: FMA:70563
has_exact_synonym: neuroblast
in subset: cellxgene subset

Axiom
annotated source: neuroblast (sensu Vertebrata)
annotated property: definition
annotated target: A cell that will develop into a neuron often after a migration phase.
database_cross_reference: GOC:NV
database_cross_reference: http://en.wikipedia.org/wiki/Neuroblast

stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: eukaryotic cell
subclass of: precursor cell
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon_33208
subclass of: Restriction
  on property: capable of
  some values from: GO_0017145
definition: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
RO_0002175: NCBITaxon 9606
database_cross_reference: CALOHA:TS-2086
database_cross_reference: FMA:63368
has_exact_synonym: animal stem cell
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas
comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’.

Axiom
annotated source: stem cell
annotated property: definition
annotated target: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D013234

single fate stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001400
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: somatic stem cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001400
definition: A stem cell that self-renews as well as give rise to a single mature cell type.
database_cross_reference: FMA:70569
has_exact_synonym: unipotent stem cell
has_exact_synonym: unipotential stem cell

Axiom
annotated source: single fate stem cell
annotated property: definition
annotated target: A stem cell that self-renews as well as give rise to a single mature cell type.
database_cross_reference: GOC:tfm

epithelial fate stem cell
type: Class
subclass of: single fate stem cell
RO_0002175: NCBITaxon 9606
has_exact_synonym: epithelial stem cell
in subset: cellxgene subset
in subset: human reference atlas

hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: capable of
    some values from: GO_0002244
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048103
subclass of: somatic stem cell
subclass of: hematopoietic precursor cell
subclass of: progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: develops from
  some values from: angioblastic mesenchymal cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0002244
definition: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000725
database_cross_reference: CALOHA:TS-0448
database_cross_reference: FMA:86475
database_cross_reference: MESH:D006412
database_cross_reference: VHOG:0001485
has_exact_synonym: blood forming stem cell
has_exact_synonym: hemopoietic stem cell
has related synonym: HSC
has related synonym: colony forming unit hematopoietic
in subset: blood and immune upper slim
in subset: cellxgene subset
in subset: human reference atlas
comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.

Axiom
annotated source: hematopoietic stem cell
annotated property: definition
annotated target: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
database_cross_reference: GOC:add
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19022770
database_cross_reference: http://en.wikipedia.org/wiki/Hematopoietic_stem_cell

Axiom
annotated source: hematopoietic stem cell
annotated property: hasRelatedSynonym
annotated target: HSC
has synonym type: OMO_0003000

erythroid progenitor cell
type: Class
subclass of: erythroid lineage cell
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: develops from
  some values from: megakaryocyte-erythroid progenitor cell
definition: A progenitor cell committed to the erythroid lineage.
database_cross_reference: BTO:0004911
has related synonym: BFU-E
has related synonym: CFU-E
has related synonym: blast forming unit erythroid
has related synonym: burst forming unit erythroid
has related synonym: colony forming unit erythroid
has related synonym: erythroid stem cell
in subset: blood and immune upper slim
in subset: cellxgene subset

Axiom
annotated source: erythroid progenitor cell
annotated property: subClassOf
annotated target: myeloid lineage restricted progenitor cell
is inferred: true

Axiom
annotated source: erythroid progenitor cell
annotated property: definition
annotated target: A progenitor cell committed to the erythroid lineage.
database_cross_reference: GOC:add
database_cross_reference: ISBN:0721601464

Axiom
annotated source: erythroid progenitor cell
annotated property: hasRelatedSynonym
annotated target: BFU-E
has synonym type: OMO_0003000

Axiom
annotated source: erythroid progenitor cell
annotated property: hasRelatedSynonym
annotated target: CFU-E
has synonym type: OMO_0003000

germ line cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0022414
definition: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
in subset: general cell types upper slim
in subset: upper level
comment: Originally this term had some plant germ line cell children.

Axiom
annotated source: germ line cell
annotated property: definition
annotated target: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

multi fate stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001402
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: stem cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001402
definition: A stem cell that can give rise to multiple lineages of cells.
database_cross_reference: FMA:84789
has_exact_synonym: multi-fate stem cell
has_exact_synonym: multifate stem cell
has_exact_synonym: multipotent cell
has_exact_synonym: multipotent stem cell

Axiom
annotated source: multi fate stem cell
annotated property: definition
annotated target: A stem cell that can give rise to multiple lineages of cells.
database_cross_reference: GOC:add

common myeloid progenitor
type: Class
subclass of: hematopoietic oligopotent progenitor cell
disjoint with: megakaryocyte-erythroid progenitor cell
definition: A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0004730
has_exact_synonym: common myeloid precursor
has related synonym: CFU-GEMM
has related synonym: CFU-S
has related synonym: CMP
has related synonym: colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte
has related synonym: multipotential myeloid stem cell
has related synonym: myeloid stem cell
has related synonym: pluripotent stem cell (bone marrow)
in subset: cellxgene subset
in subset: human reference atlas
comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059).

Axiom
annotated source: common myeloid progenitor
annotated property: subClassOf
annotated target: hematopoietic oligopotent progenitor cell
is inferred: true

Axiom
annotated source: common myeloid progenitor
annotated property: definition
annotated target: A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages.
database_cross_reference: GOC:add
database_cross_reference: ISBN:0878932437
database_cross_reference: MESH:D023461

Axiom
annotated source: common myeloid progenitor
annotated property: hasRelatedSynonym
annotated target: CFU-GEMM
database_cross_reference: ISBN:0878932437
has synonym type: OMO_0003000

Axiom
annotated source: common myeloid progenitor
annotated property: hasRelatedSynonym
annotated target: CFU-S
database_cross_reference: ISBN:0878932437
has synonym type: OMO_0003000

Axiom
annotated source: common myeloid progenitor
annotated property: hasRelatedSynonym
annotated target: CMP
database_cross_reference: ISBN:0878932437
has synonym type: OMO_0003000

Axiom
annotated source: common myeloid progenitor
annotated property: hasRelatedSynonym
annotated target: colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte
database_cross_reference: ISBN:0878932437

Axiom
annotated source: common myeloid progenitor
annotated property: hasRelatedSynonym
annotated target: multipotential myeloid stem cell
database_cross_reference: ISBN:0878932437

Axiom
annotated source: common myeloid progenitor
annotated property: hasRelatedSynonym
annotated target: myeloid stem cell
database_cross_reference: ISBN:0878932437

Axiom
annotated source: common myeloid progenitor
annotated property: hasRelatedSynonym
annotated target: pluripotent stem cell (bone marrow)
database_cross_reference: ISBN:0878932437

megakaryocyte-erythroid progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic oligopotent progenitor cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030218
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030219
subclass of: myeloid cell
subclass of: hematopoietic oligopotent progenitor cell
subclass of: progenitor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0030218
subclass of: Restriction
  on property: capable of
  some values from: GO_0030219
definition: A progenitor cell committed to the megakaryocyte and erythroid lineages.
RO_0002175: NCBITaxon 9606
has_exact_synonym: CFU-EM
has_exact_synonym: CFU-MegE
has_exact_synonym: MEP
has_exact_synonym: Meg/E progenitor
has_exact_synonym: colony forming unit erythroid megakaryocyte
has_exact_synonym: megakaryocyte/erythrocyte progenitor
has_exact_synonym: megakaryocyte/erythroid progenitor cell
in subset: cellxgene subset
in subset: human reference atlas
comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2.

Axiom
annotated source: megakaryocyte-erythroid progenitor cell
annotated property: subClassOf
annotated target: hematopoietic oligopotent progenitor cell
is inferred: true

Axiom
annotated source: megakaryocyte-erythroid progenitor cell
annotated property: definition
annotated target: A progenitor cell committed to the megakaryocyte and erythroid lineages.
database_cross_reference: GOC:add
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D055015
database_cross_reference: PMID:16647566
database_cross_reference: http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell

totipotent stem cell
type: Class
subclass of: somatic stem cell
definition: A stem cell from which all cells of the body can form.
database_cross_reference: FMA:84790
database_cross_reference: MESH:D039901
has_exact_synonym: totipotential stem cell

Axiom
annotated source: totipotent stem cell
annotated property: definition
annotated target: A stem cell from which all cells of the body can form.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm

non-terminally differentiated cell
type: Class
subclass of: precursor cell
definition: A precursor cell with a limited number of potential fates.
database_cross_reference: BTO:0000125
database_cross_reference: FMA:84782
has_exact_synonym: blast cell
in subset: cellxgene subset
comment: define using PATO mulit-potent or oligopotent?

Axiom
annotated source: non-terminally differentiated cell
annotated property: definition
annotated target: A precursor cell with a limited number of potential fates.
database_cross_reference: SANBI:mhl

myoblast
type: Class
subclass of: muscle precursor cell
definition: A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair.
database_cross_reference: BTO:0000222
database_cross_reference: CALOHA:TS-0650
database_cross_reference: FMA:70335
database_cross_reference: VHOG:0001529
in subset: cellxgene subset

Axiom
annotated source: myoblast
annotated property: definition
annotated target: A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D032446
database_cross_reference: PMID:21849021

fibroblast
type: Class
subclass of: stromal cell
definition: A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000452
database_cross_reference: CALOHA:TS-0362
database_cross_reference: FMA:63877
database_cross_reference: NCIT:C12482
database_cross_reference: VHOG:0001482
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas
comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

Axiom
annotated source: fibroblast
annotated property: definition
annotated target: A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
database_cross_reference: ISBN:0517223651
database_cross_reference: MESH:D005347
database_cross_reference: http://en.wikipedia.org/wiki/Fibroblast

chondroblast
type: Class
subclass of: non-terminally differentiated cell
subclass of: connective tissue cell
subclass of: Restriction
  on property: develops from
  some values from: prechondroblast
subclass of: Restriction
  on property: produces
  some values from: UBERON_0002418
definition: Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell.
database_cross_reference: BTO:0003607
database_cross_reference: FMA:66783
has_exact_synonym: chrondoplast

Axiom
annotated source: chondroblast
annotated property: definition
annotated target: Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell.
database_cross_reference: GOC:tfm
database_cross_reference: GO_REF:0000034
database_cross_reference: ISBN:0618947256

ciliated cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has part
    some values from: GO_0005929
subclass of: eukaryotic cell
subclass of: Restriction
  on property: has part
  some values from: GO_0005929
definition: A cell that has a filiform extrusion of the cell surface.
database_cross_reference: VHOG:0001532
database_cross_reference: XAO:0000031
in subset: cellxgene subset

Axiom
annotated source: ciliated cell
annotated property: definition
annotated target: A cell that has a filiform extrusion of the cell surface.
database_cross_reference: GOC:tfm

epithelial cell
type: Class
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000483
disjoint with: leukocyte
definition: A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000414
database_cross_reference: CALOHA:TS-2026
database_cross_reference: CARO:0000077
database_cross_reference: FMA:66768
database_cross_reference: WBbt:0003672
has_exact_synonym: epitheliocyte
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas

Axiom
annotated source: epithelial cell
annotated property: definition
annotated target: A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D004847

ciliated epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: has part
    some values from: GO_0005929
subclass of: ciliated cell
subclass of: epithelial cell
definition: An epithelial cell that has a cilia.
database_cross_reference: FMA:70605
in subset: cellxgene subset

Axiom
annotated source: ciliated epithelial cell
annotated property: definition
annotated target: An epithelial cell that has a cilia.
database_cross_reference: GOC:tfm

duct epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000058
subclass of: epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000058
definition: An epithelial cell that is part of a duct.
in subset: cellxgene subset

Axiom
annotated source: duct epithelial cell
annotated property: definition
annotated target: An epithelial cell that is part of a duct.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

branched duct epithelial cell
type: Class
subclass of: duct epithelial cell

blood vessel endothelial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001981
subclass of: endothelial cell of vascular tree
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004638
definition: An endothelial cell that lines the vasculature.
RO_0002175: NCBITaxon 9606
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: blood vessel endothelial cell
annotated property: definition
annotated target: An endothelial cell that lines the vasculature.
database_cross_reference: GOC:tfm

columnar/cuboidal epithelial cell
type: Class
subclass of: epithelial cell
definition: A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
RO_0002175: NCBITaxon 9606
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: columnar/cuboidal epithelial cell
annotated property: definition
annotated target: A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
database_cross_reference: GO:0002065
database_cross_reference: https://orcid.org/0000-0001-5208-3432

squamous epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0006914
subclass of: epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0006914
definition: Any epithelial cell that is part of some squamous epithelium.
database_cross_reference: CALOHA:TS-1249
in subset: cellxgene subset

Axiom
annotated source: squamous epithelial cell
annotated property: definition
annotated target: Any epithelial cell that is part of some squamous epithelium.
database_cross_reference: FBC:Autogenerated

mesothelial cell
type: Class
subclass of: squamous epithelial cell
subclass of: lining cell
subclass of: meso-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001136
definition: A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:66773
has_exact_synonym: mesotheliocyte
in subset: cellxgene subset
in subset: human reference atlas
comment: Mesothelial cells, which morphologically resemble squamous epithelial cells, express both epithelial markers (cytokeratins) and mesenchymal markers (vimentin), reflecting their mesodermal origin. They feature surface microvilli and apical-basal polarity. Under certain conditions, they can undergo mesothelial-to-mesenchymal transition. These cells also produce extracellular matrix proteins, maintain serosal homeostasis, and facilitate fluid transport.

Axiom
annotated source: mesothelial cell
annotated property: definition
annotated target: A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
database_cross_reference: PMID:26106328

Axiom
annotated source: mesothelial cell
annotated property: comment
annotated target: Mesothelial cells, which morphologically resemble squamous epithelial cells, express both epithelial markers (cytokeratins) and mesenchymal markers (vimentin), reflecting their mesodermal origin. They feature surface microvilli and apical-basal polarity. Under certain conditions, they can undergo mesothelial-to-mesenchymal transition. These cells also produce extracellular matrix proteins, maintain serosal homeostasis, and facilitate fluid transport.
database_cross_reference: PMID:26106328

circulating cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000179
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000179
definition: A cell which moves among different tissues of the body, via blood, lymph, or other medium.

Axiom
annotated source: circulating cell
annotated property: definition
annotated target: A cell which moves among different tissues of the body, via blood, lymph, or other medium.
database_cross_reference: GOC:add

blood cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0008015
subclass of: hematopoietic cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0008015
definition: A cell found predominately in the blood.
database_cross_reference: FMA:62844
database_cross_reference: MESH:D001773
in subset: cellxgene subset
in subset: general cell types upper slim

Axiom
annotated source: blood cell
annotated property: subClassOf
annotated target: hematopoietic cell
is inferred: true

Axiom
annotated source: blood cell
annotated property: definition
annotated target: A cell found predominately in the blood.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm

epithelial cell of lung
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000115
subclass of: epithelial cell of lower respiratory tract
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000115
definition: An epithelial cell of the lung.
database_cross_reference: BTO:0004299
has_exact_synonym: lung epithelial cell
in subset: cellxgene subset

Axiom
annotated source: epithelial cell of lung
annotated property: definition
annotated target: An epithelial cell of the lung.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

epithelial cell of pancreas
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001264
definition: An epithelial cell of the pancreas.
database_cross_reference: BTO:0000028
has_exact_synonym: pancreas epithelial cell
has_exact_synonym: pancreatic epithelial cell
in subset: cellxgene subset

Axiom
annotated source: epithelial cell of pancreas
annotated property: definition
annotated target: An epithelial cell of the pancreas.
database_cross_reference: GOC:tfm

neuron associated cell
type: Class
subclass of: neural cell
subclass of: Restriction
  on property: develops from
  some values from: neurectodermal cell
in subset: cellxgene subset

sensory epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: epithelial cell
subclass of: sensory receptor cell
definition: A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.
has broad synonym: neuroepithelial cell
database_cross_reference: BTO:0004301
comment: The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710).

Axiom
annotated source: sensory epithelial cell
annotated property: definition
annotated target: A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: ISBN:0721662544

interneuron
type: Class
subclass of: CL_2000029
definition: Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0003811
database_cross_reference: FMA:67313
database_cross_reference: WBbt:0005113
has related synonym: CNS interneuron
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: interneuron
annotated property: definition
annotated target: Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D007395

motor neuron
type: Class
subclass of: efferent neuron
definition: An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000312
database_cross_reference: FMA:83617
database_cross_reference: WBbt:0005409
has_exact_synonym: motoneuron
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: motor neuron
annotated property: definition
annotated target: An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.
database_cross_reference: MESH:D009046
database_cross_reference: PMID:16875686

sensory neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: afferent neuron
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
definition: Any neuron having a sensory function; an afferent neuron conveying sensory impulses.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0001037
database_cross_reference: FMA:84649
database_cross_reference: MESH:D011984
database_cross_reference: WBbt:0005759
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: sensory neuron
annotated property: definition
annotated target: Any neuron having a sensory function; an afferent neuron conveying sensory impulses.
database_cross_reference: ISBN:0721662544

autonomic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0002410
subclass of: CL_2000032
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0002410
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: A neuron whose cell body is within an autonomic ganglion.
database_cross_reference: FMA:80121

Axiom
annotated source: autonomic neuron
annotated property: definition
annotated target: A neuron whose cell body is within an autonomic ganglion.
database_cross_reference: GOC:tfm

cholinergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0014055
subclass of: secretory cell
subclass of: neuron
subclass of: Restriction
  on property: capable of
  some values from: GO_0014055
definition: A neuron that uses acetylcholine as a vesicular neurotransmitter.
database_cross_reference: BTO:0004902
database_cross_reference: FMA:84796
database_cross_reference: MESH:D059329
database_cross_reference: WBbt:0006840

Axiom
annotated source: cholinergic neuron
annotated property: definition
annotated target: A neuron that uses acetylcholine as a vesicular neurotransmitter.
database_cross_reference: GOC:tfm

surface ectodermal cell
type: Class
equivalent class: Class
  intersection of: ectodermal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000076
subclass of: ectodermal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000076
definition: An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024).
database_cross_reference: FMA:72552
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000114
has_exact_synonym: cell of surface ectoderm
has_exact_synonym: surface ectoderm cell
in subset: cellxgene subset

Axiom
annotated source: surface ectodermal cell
annotated property: definition
annotated target: An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024).
database_cross_reference: PMID:7892198
database_cross_reference: Wikipedia:Surface_ectoderm
database_cross_reference: doi:/10.1101/2024.07.02.601324

Axiom
annotated source: surface ectodermal cell
annotated property: has_exact_synonym
annotated target: surface ectoderm cell
database_cross_reference: doi:/10.1101/2024.07.02.601324

endothelial cell
type: Class
subclass of: lining cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: develops from
  some values from: mesodermal cell
definition: An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0001176
database_cross_reference: CALOHA:TS-0278
database_cross_reference: FMA:66772
has_exact_synonym: endotheliocyte
in subset: cellxgene subset
in subset: human reference atlas
comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].

Axiom
annotated source: endothelial cell
annotated property: definition
annotated target: An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D042783
database_cross_reference: PMID:21275341
database_cross_reference: http://en.wikipedia.org/wiki/Endothelial_cell
database_cross_reference: https://sourceforge.net/tracker/

glial cell
type: Class
subclass of: neuron associated cell
definition: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0002606
database_cross_reference: CALOHA:TS-0415
database_cross_reference: FMA:54536
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000125
has_exact_synonym: neuroglial cell
has related synonym: neuroglia
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas
comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571

Axiom
annotated source: glial cell
annotated property: definition
annotated target: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.
database_cross_reference: MESH:D009457

neurectodermal cell
type: Class
subclass of: ectodermal cell
definition: Ectoderm destined to be nervous tissue.
has_exact_synonym: neurectoderm cell

Axiom
annotated source: neurectodermal cell
annotated property: definition
annotated target: Ectoderm destined to be nervous tissue.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:068340007X

mesenchymal stem cell
type: Class
subclass of: multi fate stem cell
subclass of: connective tissue cell
definition: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
database_cross_reference: BTO:0002625
database_cross_reference: BTO:0003298
database_cross_reference: FMA:70546
has narrow synonym: bone marrow stromal cells
has narrow synonym: colony-forming unit-fibroblast
has narrow synonym: marrow stromal cells
has related synonym: BMSC
has related synonym: CFU-F
has related synonym: MSC
has related synonym: mesenchymal precursor cell
has related synonym: mesenchymal progenitor cells
has related synonym: mesenchymal stem cell
has related synonym: mesenchymal stromal cell
has related synonym: mesenchymal stromal cells
has related synonym: stem cells, mesenchymal
in subset: cellxgene subset
comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.

Axiom
annotated source: mesenchymal stem cell
annotated property: subClassOf
annotated target: connective tissue cell
is inferred: true

Axiom
annotated source: mesenchymal stem cell
annotated property: definition
annotated target: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
database_cross_reference: FB:ma
database_cross_reference: GOC:dsd
database_cross_reference: PMCID:PMC2613570
database_cross_reference: PMID:10102814
database_cross_reference: PMID:16923606
database_cross_reference: PMID:17986482
database_cross_reference: PMID:19960544
database_cross_reference: http://en.wikipedia.org/wiki/Mesenchymal_stem_cell
database_cross_reference: http://www.copewithcytokines.de/cope.cgi

Axiom
annotated source: mesenchymal stem cell
annotated property: hasNarrowSynonym
annotated target: marrow stromal cells
database_cross_reference: PMID:11378515

Axiom
annotated source: mesenchymal stem cell
annotated property: hasRelatedSynonym
annotated target: BMSC
has synonym type: OMO_0003000

Axiom
annotated source: mesenchymal stem cell
annotated property: hasRelatedSynonym
annotated target: CFU-F
has synonym type: OMO_0003000

Axiom
annotated source: mesenchymal stem cell
annotated property: hasRelatedSynonym
annotated target: MSC
database_cross_reference: PMID:11378515
has synonym type: OMO_0003000

Axiom
annotated source: mesenchymal stem cell
annotated property: hasRelatedSynonym
annotated target: mesenchymal progenitor cells
database_cross_reference: MESH:D044982
has synonym type: OMO_0003004

Axiom
annotated source: mesenchymal stem cell
annotated property: hasRelatedSynonym
annotated target: mesenchymal stromal cells
has synonym type: OMO_0003004

Axiom
annotated source: mesenchymal stem cell
annotated property: hasRelatedSynonym
annotated target: stem cells, mesenchymal
database_cross_reference: MESH:D044982
has synonym type: OMO_0003004

adipocyte
type: Class
subclass of: stuff accumulating cell
subclass of: connective tissue cell
subclass of: Restriction
  on property: develops from
  some values from: mesenchymal stem cell
definition: A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000443
database_cross_reference: CALOHA:TS-0012
database_cross_reference: FMA:63880
has_exact_synonym: adipose cell
has_exact_synonym: fat cell
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas

Axiom
annotated source: adipocyte
annotated property: definition
annotated target: A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.
database_cross_reference: MESH:D017667

chondrocyte
type: Class
subclass of: glycosaminoglycan secreting cell
subclass of: collagen secreting cell
subclass of: Restriction
  on property: located in
  some values from: UBERON_0002418
subclass of: Restriction
  on property: develops from
  some values from: chondroblast
definition: Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell.
database_cross_reference: BTO:0000249
database_cross_reference: CALOHA:TS-0138
database_cross_reference: FMA:66782
has_exact_synonym: cartilage cell
in subset: cellxgene subset

Axiom
annotated source: chondrocyte
annotated property: definition
annotated target: Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell.
database_cross_reference: GO_REF:0000034
database_cross_reference: MESH:D019902

pigment cell
type: Class
subclass of: stuff accumulating cell
definition: A pigment cell is a cell that contains pigment granules.
database_cross_reference: VHOG:0001678
has_exact_synonym: chromatocyte
has_exact_synonym: chromatophore

Axiom
annotated source: pigment cell
annotated property: definition
annotated target: A pigment cell is a cell that contains pigment granules.
database_cross_reference: GOC:tfm

visual pigment cell
type: Class
subclass of: pigment cell
has broad synonym: pigment cell

glandular secretory epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: secretory cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002530
subclass of: CL_1100001
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002530
definition: An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous.
database_cross_reference: CALOHA:TS-2085
database_cross_reference: FMA:86494
has_exact_synonym: glandular epithelial cell
in subset: cellxgene subset

Axiom
annotated source: glandular secretory epithelial cell
annotated property: definition
annotated target: An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous.
database_cross_reference: GOC:tfm
database_cross_reference: ORCID:0000-0002-7073-9172

secretory cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0032940
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0032940
definition: A cell that specializes in controlled release of one or more substances.
database_cross_reference: BTO:0003659
database_cross_reference: FMA:86916
in subset: cellxgene subset

Axiom
annotated source: secretory cell
annotated property: definition
annotated target: A cell that specializes in controlled release of one or more substances.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

exocrine cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002365
subclass of: secretory cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002365
definition: A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.
database_cross_reference: FMA:16014
in subset: general cell types upper slim

Axiom
annotated source: exocrine cell
annotated property: definition
annotated target: A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.
database_cross_reference: ISBN:0198547684

glycosaminoglycan secreting cell
type: Class
subclass of: extracellular matrix secreting cell
subclass of: carbohydrate secreting cell
definition: A cell that secretes glycosaminoglycans.
has_exact_synonym: GAG secreting cell
has narrow synonym: hyaluronic acid secreting cell

Axiom
annotated source: glycosaminoglycan secreting cell
annotated property: definition
annotated target: A cell that secretes glycosaminoglycans.
database_cross_reference: GOC:tfm

protein secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0009306
subclass of: secretory cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0009306
definition: Any secretory cell that is capable of some protein secretion.

Axiom
annotated source: protein secreting cell
annotated property: definition
annotated target: Any secretory cell that is capable of some protein secretion.
database_cross_reference: FBC:Autogenerated

seromucus secreting cell
type: Class
subclass of: secretory cell

endocrine cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: Class
      intersection of: GO_0046879
      intersection of: Restriction
        on property: has target end location
        some values from: UBERON_0001009
subclass of: secretory cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000949
subclass of: Restriction
  on property: capable of
  some values from: Class
    intersection of: GO_0046879
    intersection of: Restriction
      on property: has target end location
      some values from: UBERON_0001009
definition: A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:83809
has_exact_synonym: endocrinocyte
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas

Axiom
annotated source: endocrine cell
annotated property: definition
annotated target: A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
database_cross_reference: MESH:D055098

enteroendocrine cell
type: Class
subclass of: endocrine cell
subclass of: CL_1100001
definition: An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas.
database_cross_reference: BTO:0003865
database_cross_reference: FMA:62930
database_cross_reference: MESH:D019858
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000164
in subset: cellxgene subset

Axiom
annotated source: enteroendocrine cell
annotated property: definition
annotated target: An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas.
database_cross_reference: GOC:tfm
database_cross_reference: SANBI:mhl

neuroendocrine cell
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0046879
subclass of: endocrine cell
subclass of: efferent neuron
subclass of: neurecto-epithelial cell
subclass of: CL_1100001
definition: A neuron that is capable of some hormone secretion in response to neuronal signals.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0002691
database_cross_reference: FMA:83810
has related synonym: neurosecretory cell
has related synonym: neurosecretory neuron
in subset: cellxgene subset
in subset: human reference atlas
comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron.

Axiom
annotated source: neuroendocrine cell
annotated property: definition
annotated target: A neuron that is capable of some hormone secretion in response to neuronal signals.
database_cross_reference: MESH:D055099

Axiom
annotated source: neuroendocrine cell
annotated property: comment
annotated target: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron.
database_cross_reference: PMID:5342440
database_cross_reference: https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073

peptide hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030072
subclass of: secretory cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0030072
definition: Any secretory cell that is capable of some peptide hormone secretion.

Axiom
annotated source: peptide hormone secreting cell
annotated property: definition
annotated target: Any secretory cell that is capable of some peptide hormone secretion.
database_cross_reference: FBC:Autogenerated

insulin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030073
subclass of: protein secreting cell
subclass of: peptide hormone secreting cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0030073
definition: Any secretory cell that is capable of some insulin secretion.
database_cross_reference: BTO:0000783

Axiom
annotated source: insulin secreting cell
annotated property: definition
annotated target: Any secretory cell that is capable of some insulin secretion.
database_cross_reference: FBC:Autogenerated

type B pancreatic cell
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000006
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030073
subclass of: insulin secreting cell
subclass of: pancreatic endocrine cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000006
subclass of: Restriction
  on property: develops from
  some values from: progenitor cell of endocrine pancreas
definition: A cell that secretes insulin and is located towards the center of the islets of Langerhans.
RO_0002175: NCBITaxon 9606
has broad synonym: beta cell
database_cross_reference: BTO:0000783
database_cross_reference: EV:0200009
database_cross_reference: FMA:70586
database_cross_reference: MA:0002419
database_cross_reference: ncithesaurus:Beta_Cell
has_exact_synonym: B-cell of pancreatic islet
has_exact_synonym: beta cell of pancreatic islet
has_exact_synonym: insulin-secreting cell
has_exact_synonym: pancreatic B cell
has_exact_synonym: pancreatic B-cell
has_exact_synonym: pancreatic beta cell
has_exact_synonym: pancreatic islet core
has_exact_synonym: type B enteroendocrine cell
has related synonym: beta cell islet
in subset: cellxgene subset
in subset: human reference atlas
comment: Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.

Axiom
annotated source: type B pancreatic cell
annotated property: subClassOf
annotated target: insulin secreting cell
is inferred: true

Axiom
annotated source: type B pancreatic cell
annotated property: definition
annotated target: A cell that secretes insulin and is located towards the center of the islets of Langerhans.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: http://en.wikipedia.org/wiki/Pancreatic_b_cell

Axiom
annotated source: type B pancreatic cell
annotated property: hasBroadSynonym
annotated target: beta cell
database_cross_reference: ZFA:0009102

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: B-cell of pancreatic islet
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: beta cell of pancreatic islet
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: insulin-secreting cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: pancreatic B-cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: pancreatic beta cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: pancreatic islet core
database_cross_reference: MA:0002419

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: type B enteroendocrine cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: hasRelatedSynonym
annotated target: beta cell islet
database_cross_reference: MA:0002419

glucagon secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070091
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0070091
definition: A cell that secretes glucagon.
database_cross_reference: FMA:84045
has_exact_synonym: glucagon-secreting cell

Axiom
annotated source: glucagon secreting cell
annotated property: definition
annotated target: A cell that secretes glucagon.
database_cross_reference: GOC:tfm

pancreatic A cell
type: Class
equivalent class: Class
  intersection of: type A enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: type A enteroendocrine cell
subclass of: pancreatic endocrine cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000006
subclass of: Restriction
  on property: develops from
  some values from: progenitor cell of endocrine pancreas
definition: A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000990
database_cross_reference: FMA:70585
database_cross_reference: MESH:D050416
has_exact_synonym: alpha cell of islet of Langerhans
has_exact_synonym: pancreatic alpha cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: pancreatic A cell
annotated property: definition
annotated target: A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

somatostatin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070253
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0070253
definition: Any secretory cell that is capable of some somatostatin secretion.

Axiom
annotated source: somatostatin secreting cell
annotated property: definition
annotated target: Any secretory cell that is capable of some somatostatin secretion.
database_cross_reference: FBC:Autogenerated

pancreatic D cell
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: type D enteroendocrine cell
subclass of: pancreatic endocrine cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000006
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
subclass of: Restriction
  on property: develops from
  some values from: progenitor cell of endocrine pancreas
definition: A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000803
database_cross_reference: FMA:70587
has_exact_synonym: D-cell of pancreatic islet
has_exact_synonym: delta cell of islet
has_exact_synonym: delta cell of pancreatic islet
has_exact_synonym: pancreatic D-cell
has_exact_synonym: pancreatic delta cell
has_exact_synonym: somatostatin-secreting pancreatic cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: pancreatic D cell
annotated property: definition
annotated target: A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.
database_cross_reference: FMA:0517223651
database_cross_reference: GOC:tfm

steroid hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0035929
subclass of: secretory cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0035929
definition: Any secretory cell that is capable of some steroid hormone secretion.

Axiom
annotated source: steroid hormone secreting cell
annotated property: definition
annotated target: Any secretory cell that is capable of some steroid hormone secretion.
database_cross_reference: FBC:Autogenerated

hepatocyte
type: Class
subclass of: epithelial cell
subclass of: endopolyploid cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002107
subclass of: Restriction
  on property: develops from
  some values from: hepatoblast
subclass of: Restriction
  on property: capable of
  some values from: GO_0006699
subclass of: Restriction
  on property: capable of
  some values from: GO_0098754
definition: The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000575
database_cross_reference: CALOHA:TS-0454
database_cross_reference: FMA:14515
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000182
in subset: cellxgene subset
in subset: human reference atlas
comment: Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive.

Axiom
annotated source: hepatocyte
annotated property: definition
annotated target: The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0412046911
database_cross_reference: MESH:D022781
database_cross_reference: PMID:19717280
database_cross_reference: http://en.wikipedia.org/wiki/Hepatocyte

contractile cell
type: Class
subclass of: cell
definition: A cell whose primary function is to shorten.
in subset: cellxgene subset

Axiom
annotated source: contractile cell
annotated property: definition
annotated target: A cell whose primary function is to shorten.
database_cross_reference: FB:ma

muscle cell
type: Class
subclass of: contractile cell
subclass of: eukaryotic cell
subclass of: electrically responsive cell
subclass of: Restriction
  on property: develops from
  some values from: myoblast
definition: A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
database_cross_reference: BTO:0000888
database_cross_reference: BTO:0000902
database_cross_reference: CALOHA:TS-2032
database_cross_reference: FMA:67328
database_cross_reference: WBbt:0003675
has_exact_synonym: muscle fiber
has_exact_synonym: myocyte
in subset: cellxgene subset

Axiom
annotated source: muscle cell
annotated property: definition
annotated target: A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
database_cross_reference: MESH:D032342

cell of skeletal muscle
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001134
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001134
definition: A somatic cell located in skeletal muscle.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0004392
database_cross_reference: CALOHA:TS-2158
database_cross_reference: FMA:9727
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000188
has_exact_synonym: skeletal muscle cell
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas

Axiom
annotated source: cell of skeletal muscle
annotated property: definition
annotated target: A somatic cell located in skeletal muscle.
database_cross_reference: GOC:tfm

smooth muscle cell
type: Class
subclass of: non-striated muscle cell
subclass of: visceral muscle cell
subclass of: Restriction
  on property: develops from
  some values from: smooth muscle myoblast
definition: A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).
RO_0002175: NCBITaxon 9606
has broad synonym: non-striated muscle cell
database_cross_reference: BTO:0004576
database_cross_reference: CALOHA:TS-2159
database_cross_reference: FMA:14072
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000192
has_exact_synonym: SMCs
has_exact_synonym: myocytes, smooth muscle
has_exact_synonym: smooth muscle fiber
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas

Axiom
annotated source: smooth muscle cell
annotated property: definition
annotated target: A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).
database_cross_reference: MESH:D032389
database_cross_reference: PMID:9315361
database_cross_reference: http://en.wikipedia.org/wiki/Smooth_muscle_cell

Axiom
annotated source: smooth muscle cell
annotated property: has_exact_synonym
annotated target: SMCs
database_cross_reference: PMID:9315361

Axiom
annotated source: smooth muscle cell
annotated property: has_exact_synonym
annotated target: myocytes, smooth muscle
database_cross_reference: MESH:D032389

sensory receptor cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001032
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001032
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
definition: A cell that is capable of detection of a stimulus involved in sensory perception.
database_cross_reference: MESH:D011984
has_exact_synonym: receptor cell

chemoreceptor cell
type: Class
equivalent class: Class
  intersection of: sensory receptor cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050907
subclass of: sensory receptor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0050907
definition: A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.

Axiom
annotated source: chemoreceptor cell
annotated property: definition
annotated target: A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.
database_cross_reference: MESH:D002628

photoreceptor cell
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050908
subclass of: sensory neuron
subclass of: visual system neuron
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: A cell specialized in detecting light stimuli that are involved in visual perception.
database_cross_reference: BTO:0001060
database_cross_reference: CALOHA:TS-0868
database_cross_reference: FMA:86740
in subset: cellxgene subset

Axiom
annotated source: photoreceptor cell
annotated property: definition
annotated target: A cell specialized in detecting light stimuli that are involved in visual perception.
database_cross_reference: MESH:D010786

electrically active cell
type: Class
subclass of: cell
definition: A cell whose function is determined by the generation or the reception of an electric signal.

Axiom
annotated source: electrically active cell
annotated property: definition
annotated target: A cell whose function is determined by the generation or the reception of an electric signal.
database_cross_reference: FB:ma

lining cell
type: Class
subclass of: barrier cell
definition: A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism.
has_exact_synonym: boundary cell

Axiom
annotated source: lining cell
annotated property: definition
annotated target: A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism.
database_cross_reference: JB:jb

synovial cell
type: Class
subclass of: lining cell
subclass of: meso-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002217
definition: A cell located in the synovial joint.
database_cross_reference: CALOHA:TS-0995
has_exact_synonym: synoviocyte

Axiom
annotated source: synovial cell
annotated property: subClassOf
annotated target: meso-epithelial cell
is inferred: true

barrier cell
type: Class
subclass of: cell
definition: A cell whose primary function is to prevent the transport of stuff across compartments.

Axiom
annotated source: barrier cell
annotated property: definition
annotated target: A cell whose primary function is to prevent the transport of stuff across compartments.
database_cross_reference: JB:jb

motile cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048870
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0048870
definition: A cell that moves by its own activities.

Axiom
annotated source: motile cell
annotated property: definition
annotated target: A cell that moves by its own activities.
database_cross_reference: FB:ma

ectodermal cell
type: Class
subclass of: eukaryotic cell
subclass of: embryonic cell (metazoa)
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000924
definition: A cell of the outer of the three germ layers of the embryo.
database_cross_reference: FMA:72549
has_exact_synonym: ectoderm cell
in subset: cellxgene subset

Axiom
annotated source: ectodermal cell
annotated property: definition
annotated target: A cell of the outer of the three germ layers of the embryo.
database_cross_reference: MESH:D004475

mesodermal cell
type: Class
subclass of: eukaryotic cell
subclass of: embryonic cell (metazoa)
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000926
definition: A cell of the middle germ layer of the embryo.
database_cross_reference: FMA:72554
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000222
has_exact_synonym: mesoblast
has_exact_synonym: mesoderm cell
in subset: cellxgene subset

Axiom
annotated source: mesodermal cell
annotated property: definition
annotated target: A cell of the middle germ layer of the embryo.
database_cross_reference: MESH:D008648

endodermal cell
type: Class
subclass of: eukaryotic cell
subclass of: embryonic cell (metazoa)
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000925
definition: A cell of the inner of the three germ layers of the embryo.
database_cross_reference: FMA:72555
has_exact_synonym: endoderm cell

Axiom
annotated source: endodermal cell
annotated property: definition
annotated target: A cell of the inner of the three germ layers of the embryo.
database_cross_reference: MESH:D004707

multinucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001908
subclass of: eukaryotic cell
subclass of: nucleate cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001908
definition: A cell with more than one nucleus.
has_exact_synonym: multinucleated cells
has_exact_synonym: polynuclear cells

Axiom
annotated source: multinucleate cell
annotated property: definition
annotated target: A cell with more than one nucleus.
database_cross_reference: FB:ma
database_cross_reference: Wikipedia:Multinucleate

Axiom
annotated source: multinucleate cell
annotated property: has_exact_synonym
annotated target: multinucleated cells
database_cross_reference: Wikipedia:Multinucleate

Axiom
annotated source: multinucleate cell
annotated property: has_exact_synonym
annotated target: polynuclear cells
database_cross_reference: Wikipedia:Multinucleate

erythrocyte
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0005840
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001945
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002039
  intersection of: Restriction
    on property: capable of
    some values from: GO_0008015
  intersection of: Restriction
    on property: capable of
    some values from: GO_0015671
subclass of: blood cell
subclass of: oxygen accumulating cell
subclass of: erythroid lineage cell
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0005840
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001945
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002039
subclass of: Restriction
  on property: develops from
  some values from: reticulocyte
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000424
database_cross_reference: CALOHA:TS-0290
database_cross_reference: FMA:81100
has_exact_synonym: RBC
has_exact_synonym: red blood cell
in subset: blood and immune upper slim
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: erythrocyte
annotated property: subClassOf
annotated target: erythroid lineage cell
is inferred: true

Axiom
annotated source: erythrocyte
annotated property: definition
annotated target: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D004912

eukaryotic cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: in taxon
    some values from: NCBITaxon 2759
subclass of: cell
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon 2759
definition: Any cell that in taxon some Eukaryota.
database_cross_reference: MESH:D005057

Axiom
annotated source: eukaryotic cell
annotated property: definition
annotated target: Any cell that in taxon some Eukaryota.
database_cross_reference: FBC:Autogenerated

eye photoreceptor cell
type: Class
equivalent class: Class
  intersection of: photoreceptor cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000970
subclass of: neuronal receptor cell
subclass of: photoreceptor cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000970
definition: Any photoreceptor cell that is part of some eye.
RO_0002175: NCBITaxon 9606
in subset: cellxgene subset
in subset: eye upper slim
in subset: human reference atlas

Axiom
annotated source: eye photoreceptor cell
annotated property: definition
annotated target: Any photoreceptor cell that is part of some eye.
database_cross_reference: FBC:Autogenerated

structural cell
type: Class
subclass of: cell
definition: A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.

Axiom
annotated source: structural cell
annotated property: definition
annotated target: A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.
database_cross_reference: TAIR:sr

gamete
type: Class
equivalent class: Class
  intersection of: germ cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001375
  intersection of: Restriction
    on property: capable of
    some values from: GO_0009566
subclass of: haploid cell
subclass of: germ cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0009566
definition: A mature sexual reproductive cell having a single set of unpaired chromosomes.
database_cross_reference: CALOHA:TS-0395
database_cross_reference: FMA:18649
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000300
has_exact_synonym: haploid nucleated cell
has related synonym: haploid germ cell

Axiom
annotated source: gamete
annotated property: subClassOf
annotated target: germ cell
is inferred: true

Axiom
annotated source: gamete
annotated property: definition
annotated target: A mature sexual reproductive cell having a single set of unpaired chromosomes.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

crystallin accumulating cell
type: Class
subclass of: stuff accumulating cell
has_exact_synonym: lens cell
in subset: eye upper slim

tracheal epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0003126
subclass of: epithelial cell of tracheobronchial tree
subclass of: Restriction
  on property: part of
  some values from: UBERON_0003126
subclass of: Restriction
  on property: develops from
  some values from: tracheoblast
definition: An epithelial cell found in the trachea.
database_cross_reference: FMA:74793
has_exact_synonym: tracheocyte
comment: This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell'

Axiom
annotated source: tracheal epithelial cell
annotated property: subClassOf
annotated target: epithelial cell of tracheobronchial tree
is inferred: true

Axiom
annotated source: tracheal epithelial cell
annotated property: definition
annotated target: An epithelial cell found in the trachea.
database_cross_reference: GOC:tfm

serous secreting cell
type: Class
subclass of: seromucus secreting cell
definition: Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid.
database_cross_reference: BTO:0003687
database_cross_reference: FMA:62511
has_exact_synonym: serous cell
in subset: cellxgene subset

Axiom
annotated source: serous secreting cell
annotated property: definition
annotated target: Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: ISBN:0721662544

mucus secreting cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070254
subclass of: seromucus secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0070254
definition: Any cell that is capable of some mucus secretion.
database_cross_reference: BTO:0003689
has_exact_synonym: mucous cell
in subset: cellxgene subset

Axiom
annotated source: mucus secreting cell
annotated property: definition
annotated target: Any cell that is capable of some mucus secretion.
database_cross_reference: FBC:Autogenerated

stuff accumulating cell
type: Class
subclass of: cell
definition: A cell that is specialised to accumulate a particular substance(s).
in subset: upper level

Axiom
annotated source: stuff accumulating cell
annotated property: definition
annotated target: A cell that is specialised to accumulate a particular substance(s).
database_cross_reference: FB:ma

extracellular matrix secreting cell
type: Class
subclass of: stromal cell

oxygen accumulating cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0015671
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0015671
definition: Any cell that is capable of some oxygen transport.

Axiom
annotated source: oxygen accumulating cell
annotated property: definition
annotated target: Any cell that is capable of some oxygen transport.
database_cross_reference: FBC:Autogenerated

migratory neural crest cell
type: Class
subclass of: motile cell
subclass of: neural crest cell
subclass of: progenitor cell
subclass of: Restriction
  on property: develops from
  some values from: premigratory neural crest cell
definition: A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.
database_cross_reference: FMA:86667

Axiom
annotated source: migratory neural crest cell
annotated property: definition
annotated target: A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.
database_cross_reference: doi:10.1016/j.stem.2015.02.017

mesenchyme condensation cell
type: Class
subclass of: mesenchymal cell
definition: A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.

Axiom
annotated source: mesenchyme condensation cell
annotated property: definition
annotated target: A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:5025404

scleral cell
type: Class
equivalent class: Class
  intersection of: structural cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001773
subclass of: eukaryotic cell
subclass of: structural cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001773
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
definition: A cell of the sclera of the eye.
in subset: eye upper slim

Axiom
annotated source: scleral cell
annotated property: definition
annotated target: A cell of the sclera of the eye.
database_cross_reference: GOC:add

choroidal cell of the eye
type: Class
equivalent class: Class
  intersection of: structural cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001776
subclass of: eukaryotic cell
subclass of: structural cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001776
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
definition: A structural cell that is part of optic choroid.
in subset: eye upper slim

Axiom
annotated source: choroidal cell of the eye
annotated property: definition
annotated target: A structural cell that is part of optic choroid.
database_cross_reference: GOC:add

extraembryonic cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000478
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000478
definition: Any cell that is part of some extraembryonic structure.
in subset: cellxgene subset
in subset: general cell types upper slim

Axiom
annotated source: extraembryonic cell
annotated property: definition
annotated target: Any cell that is part of some extraembryonic structure.
database_cross_reference: FBC:Autogenerated

trophoblast cell
type: Class
subclass of: extraembryonic cell
subclass of: Restriction
  on property: develops from
  some values from: trophectodermal cell
definition: An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development.
database_cross_reference: FMA:83028
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000351
has_exact_synonym: trophoblastic cell

Axiom
annotated source: trophoblast cell
annotated property: subClassOf
annotated target: extraembryonic cell
is inferred: true

Axiom
annotated source: trophoblast cell
annotated property: definition
annotated target: An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D014327
database_cross_reference: PMID:37630754
database_cross_reference: doi:10.1007/978-3-030-84725-8

Axiom
annotated source: trophoblast cell
annotated property: has_exact_synonym
annotated target: trophoblastic cell
database_cross_reference: doi:10.1007/978-3-030-84725-8

epiblast cell
type: Class
subclass of: totipotent stem cell
definition: A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation.

Axiom
annotated source: epiblast cell
annotated property: definition
annotated target: A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256

blastoderm cell
type: Class
subclass of: early embryonic cell (metazoa)
definition: An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).
database_cross_reference: BTO:0001473
database_cross_reference: FMA:72551
has_exact_synonym: blastomere

Axiom
annotated source: blastoderm cell
annotated property: definition
annotated target: An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).
database_cross_reference: MESH:D001756

multi-potent skeletal muscle stem cell
type: Class
equivalent class: Class
  intersection of: multi fate stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001134
subclass of: multi fate stem cell
subclass of: cell of skeletal muscle
definition: A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell.
database_cross_reference: FMA:86767
comment: Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo.

Axiom
annotated source: multi-potent skeletal muscle stem cell
annotated property: subClassOf
annotated target: multi fate stem cell
is inferred: true

Axiom
annotated source: multi-potent skeletal muscle stem cell
annotated property: definition
annotated target: A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell.
database_cross_reference: PMID:18282570

sphincter associated smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004590
subclass of: smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004590
definition: A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000358

Axiom
annotated source: sphincter associated smooth muscle cell
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: sphincter associated smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.
database_cross_reference: GOC:cjm

vascular associated smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002049
subclass of: smooth muscle cell
subclass of: CL_4033054
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002049
definition: A smooth muscle cell associated with the vasculature.
RO_0002175: NCBITaxon 9606
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000359
has_exact_synonym: VSMC
has_exact_synonym: vascular smooth muscle cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: vascular associated smooth muscle cell
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: vascular associated smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell associated with the vasculature.
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm

epidermal cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007376
subclass of: general ecto-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007376
definition: An epithelial cell of the integument (the outer layer of an organism).
database_cross_reference: BTO:0001470
database_cross_reference: CALOHA:TS-0283
database_cross_reference: FMA:62411
database_cross_reference: MESH:D000078404
has_exact_synonym: cell of epidermis
has narrow synonym: epithelial cell of skin
in subset: cellxgene subset

Axiom
annotated source: epidermal cell
annotated property: definition
annotated target: An epithelial cell of the integument (the outer layer of an organism).
database_cross_reference: Flybase:dsj
database_cross_reference: MA:ma

Axiom
annotated source: epidermal cell
annotated property: has_exact_synonym
annotated target: cell of epidermis
database_cross_reference: FMA:62411

Axiom
annotated source: epidermal cell
annotated property: hasNarrowSynonym
annotated target: epithelial cell of skin
database_cross_reference: FMA:62411

animal zygote
type: Class
equivalent class: Class
  intersection of: zygote
  intersection of: Restriction
    on property: in taxon
    some values from: NCBITaxon_33208
subclass of: early embryonic cell (metazoa)
subclass of: eukaryotic cell
subclass of: zygote
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon_33208
definition: Diploid cell produced by the fusion of sperm cell nucleus and egg cell.
has broad synonym: zygote
database_cross_reference: BTO:0000854
database_cross_reference: EHDAA2:0004546
database_cross_reference: FMA:72395

Axiom
annotated source: animal zygote
annotated property: definition
annotated target: Diploid cell produced by the fusion of sperm cell nucleus and egg cell.
database_cross_reference: ISBN:0471245208

tracheoblast
type: Class
subclass of: branched duct epithelial cell

electrically responsive cell
type: Class
subclass of: electrically active cell
definition: A cell whose function is determined by its response to an electric signal.

Axiom
annotated source: electrically responsive cell
annotated property: definition
annotated target: A cell whose function is determined by its response to an electric signal.
database_cross_reference: FB:ma

ganglion interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0000045
subclass of: interneuron
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0000045
definition: Any interneuron that has its soma located in some ganglion.
in subset: cellxgene subset

Axiom
annotated source: ganglion interneuron
annotated property: subClassOf
annotated target: interneuron
is inferred: true

Axiom
annotated source: ganglion interneuron
annotated property: definition
annotated target: Any interneuron that has its soma located in some ganglion.
database_cross_reference: FBC:Autogenerated

electrically signaling cell
type: Class
subclass of: electrically active cell
definition: A cell that initiates an electrical signal and passes that signal to another cell.

Axiom
annotated source: electrically signaling cell
annotated property: definition
annotated target: A cell that initiates an electrical signal and passes that signal to another cell.
database_cross_reference: FB:ma

polyploid cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001377
subclass of: cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001377
definition: A cell that contains more than two haploid sets of chromosomes.

Axiom
annotated source: polyploid cell
annotated property: definition
annotated target: A cell that contains more than two haploid sets of chromosomes.
database_cross_reference: FB:ma
database_cross_reference: PMID:32646579
database_cross_reference: https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy

haploid cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001375
subclass of: cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001375
definition: A cell whose nucleus contains a single haploid genome.

Axiom
annotated source: haploid cell
annotated property: definition
annotated target: A cell whose nucleus contains a single haploid genome.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm

endopolyploid cell
type: Class
subclass of: polyploid cell

carbohydrate secreting cell
type: Class
subclass of: secretory cell

biogenic amine secreting cell
type: Class
subclass of: secretory cell

serotonin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0001820
subclass of: biogenic amine secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0001820
definition: A cell type that secretes 5-Hydroxytryptamine (serotonin).
has_exact_synonym: 5-HT secreting cell
has_exact_synonym: 5-Hydroxytryptamine secreting cell

Axiom
annotated source: serotonin secreting cell
annotated property: definition
annotated target: A cell type that secretes 5-Hydroxytryptamine (serotonin).
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19630576

noradrenergic cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048243
subclass of: biogenic amine secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0048243
definition: A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme.
has_exact_synonym: noradrenaline secreting cell
has_exact_synonym: norepinephrin secreting cell
has_exact_synonym: norepinephrine secreting cell
in subset: cellxgene subset

Axiom
annotated source: noradrenergic cell
annotated property: definition
annotated target: A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:068340007X

visible light photoreceptor cell
type: Class
equivalent class: Class
  intersection of: photoreceptor cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0009584
subclass of: photoreceptor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0009584
definition: A photoreceptor cell that detects visible light.

Axiom
annotated source: visible light photoreceptor cell
annotated property: definition
annotated target: A photoreceptor cell that detects visible light.
database_cross_reference: GOC:tfm

stromal cell
type: Class
subclass of: connective tissue cell
subclass of: Restriction
  on property: develops from
  some values from: mesenchymal stem cell
definition: A connective tissue cell of an organ found in the loose connective tissue.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0002064
database_cross_reference: FMA:83624
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas

Axiom
annotated source: stromal cell
annotated property: definition
annotated target: A connective tissue cell of an organ found in the loose connective tissue.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D017154

type D enteroendocrine cell
type: Class
subclass of: enteroendocrine cell
subclass of: neuroendocrine cell
subclass of: somatostatin secreting cell
definition: A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin.
database_cross_reference: FMA:62935
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000502
has_exact_synonym: D cell
in subset: cellxgene subset

Axiom
annotated source: type D enteroendocrine cell
annotated property: definition
annotated target: A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin.
database_cross_reference: MESH:D019864

enkephalin secreting cell
type: Class
subclass of: endorphin secreting cell
definition: An endorphine cell that secretes enkephalin.

Axiom
annotated source: enkephalin secreting cell
annotated property: definition
annotated target: An endorphine cell that secretes enkephalin.
database_cross_reference: GO:tfm

endorphin secreting cell
type: Class
subclass of: peptide hormone secreting cell
definition: A peptide hormone secreting cell that secretes endorphin.

Axiom
annotated source: endorphin secreting cell
annotated property: definition
annotated target: A peptide hormone secreting cell that secretes endorphin.
database_cross_reference: GO:tfm

type G enteroendocrine cell
type: Class
subclass of: enteroendocrine cell
subclass of: neuroendocrine cell
subclass of: enkephalin secreting cell
subclass of: gastrin secreting cell
definition: An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli.
database_cross_reference: BTO:0004108
database_cross_reference: FMA:67609
has_exact_synonym: G cell
in subset: cellxgene subset

Axiom
annotated source: type G enteroendocrine cell
annotated property: definition
annotated target: An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: MESH:D019863
database_cross_reference: PMID:10700044
database_cross_reference: PMID:35674015
database_cross_reference: PMID:37240181

gastrin secreting cell
type: Class
subclass of: peptide hormone secreting cell
definition: A peptide hormone secreting cell that secretes gastrin.
RO_0002175: NCBITaxon 9606
in subset: human reference atlas

Axiom
annotated source: gastrin secreting cell
annotated property: definition
annotated target: A peptide hormone secreting cell that secretes gastrin.
database_cross_reference: GO:tfm

cardiac muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001133
  intersection of: Restriction
    on property: develops into
    some values from: cardiac muscle cell
subclass of: cardiocyte
subclass of: cardiac myoblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001133
definition: A precursor cell destined to differentiate into cardiac muscle cell.
database_cross_reference: FMA:84797
has_exact_synonym: cardiac muscle progenitor cell
has_exact_synonym: cardiomyocyte progenitor cell
in subset: cellxgene subset

Axiom
annotated source: cardiac muscle myoblast
annotated property: definition
annotated target: A precursor cell destined to differentiate into cardiac muscle cell.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D032386

smooth muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: develops into
    some values from: smooth muscle cell
subclass of: myoblast
subclass of: Restriction
  on property: develops into
  some values from: smooth muscle cell
definition: A precursor cell destined to differentiate into smooth muscle myocytes.
database_cross_reference: FMA:84798
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000514
has_exact_synonym: myoblast, smooth muscle
has related synonym: satellite cell
in subset: cellxgene subset

Axiom
annotated source: smooth muscle myoblast
annotated property: definition
annotated target: A precursor cell destined to differentiate into smooth muscle myocytes.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D032390

Axiom
annotated source: smooth muscle myoblast
annotated property: has_exact_synonym
annotated target: myoblast, smooth muscle
database_cross_reference: MESH:D032390

skeletal muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: develops into
    some values from: skeletal muscle fiber
subclass of: myoblast
subclass of: progenitor cell
subclass of: Restriction
  on property: develops from
  some values from: multi-potent skeletal muscle stem cell
subclass of: Restriction
  on property: develops into
  some values from: skeletal muscle fiber
definition: A myoblast that differentiates into skeletal muscle fibers.
database_cross_reference: FMA:84799
has_exact_synonym: skeletal myoblast

Axiom
annotated source: skeletal muscle myoblast
annotated property: definition
annotated target: A myoblast that differentiates into skeletal muscle fibers.
database_cross_reference: SANBI:mhl

fungal cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: in taxon
    some values from: NCBITaxon 4751
subclass of: eukaryotic cell
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon 4751
definition: Any cell that in taxon some Fungi.

Axiom
annotated source: fungal cell
annotated property: definition
annotated target: Any cell that in taxon some Fungi.
database_cross_reference: FBC:Autogenerated

syncytiotrophoblast cell
type: Class
equivalent class: Class
  intersection of: trophoblast cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001908
subclass of: trophoblast cell
subclass of: CL_4052002
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000371
definition: A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:83043
has_exact_synonym: syncytial trophoblast cell
has_exact_synonym: syncytiotrophoblastic cell
has related synonym: plasmidotrophoblast cell
has related synonym: syntrophoblast cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: syncytiotrophoblast cell
annotated property: definition
annotated target: A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0323052908

Axiom
annotated source: syncytiotrophoblast cell
annotated property: has_exact_synonym
annotated target: syncytial trophoblast cell
database_cross_reference: PMID:11787150

Axiom
annotated source: syncytiotrophoblast cell
annotated property: has_exact_synonym
annotated target: syncytiotrophoblastic cell
database_cross_reference: PMID:21733368

afferent neuron
type: Class
subclass of: neuron
definition: A neuron which conveys sensory information centrally from the periphery.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:87653
has_exact_synonym: input neuron
in subset: human reference atlas

Axiom
annotated source: afferent neuron
annotated property: definition
annotated target: A neuron which conveys sensory information centrally from the periphery.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D009475

efferent neuron
type: Class
subclass of: neuron
definition: A neuron which sends impulses peripherally to activate muscles or secretory cells.
has_exact_synonym: output neuron
in subset: cellxgene subset

Axiom
annotated source: efferent neuron
annotated property: definition
annotated target: A neuron which sends impulses peripherally to activate muscles or secretory cells.
database_cross_reference: MESH:D009476

neuron
type: Class
subclass of: electrically responsive cell
subclass of: electrically signaling cell
subclass of: neural cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0019226
definition: The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000938
database_cross_reference: CALOHA:TS-0683
database_cross_reference: FMA:54527
database_cross_reference: VHOG:0001483
database_cross_reference: WBbt:0003679
has_exact_synonym: nerve cell
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas
comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma.

Axiom
annotated source: neuron
annotated property: definition
annotated target: The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
database_cross_reference: MESH:D009474
database_cross_reference: http://en.wikipedia.org/wiki/Neuron

proerythroblast
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: has part
    some values from: basophilic cytoplasm
  intersection of: Restriction
    on property: has part
    some values from: GO_0005730
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002505
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0040072
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000001945
subclass of: erythroid lineage cell
subclass of: nucleate cell
subclass of: Restriction
  on property: has part
  some values from: basophilic cytoplasm
subclass of: Restriction
  on property: has part
  some values from: GO_0005730
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0040072
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000001945
subclass of: Restriction
  on property: develops from
  some values from: erythroid progenitor cell
definition: An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.
database_cross_reference: FMA:83518
has_exact_synonym: rubriblast
has related synonym: pronormoblast
in subset: blood and immune upper slim
in subset: cellxgene subset

Axiom
annotated source: proerythroblast
annotated property: subClassOf
annotated target: erythroid lineage cell
is inferred: true

Axiom
annotated source: proerythroblast
annotated property: definition
annotated target: An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.
database_cross_reference: ISBN:0721601464
database_cross_reference: PMID:1638021

Axiom
annotated source: proerythroblast
annotated property: has_exact_synonym
annotated target: rubriblast
database_cross_reference: ISBN:0721601464

basophilic erythroblast
type: Class
equivalent class: Class
  intersection of: erythroblast
  intersection of: Restriction
    on property: has part
    some values from: basophilic cytoplasm
  intersection of: Restriction
    on property: has part
    some values from: GO_0000792
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000001945
subclass of: erythroblast
subclass of: Restriction
  on property: has part
  some values from: basophilic cytoplasm
subclass of: Restriction
  on property: has part
  some values from: GO_0000792
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000001945
definition: A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.
database_cross_reference: FMA:83505
has_exact_synonym: basophilic normoblast
has_exact_synonym: early erythroblast
has_exact_synonym: early normoblast
has_exact_synonym: prorubricyte

Axiom
annotated source: basophilic erythroblast
annotated property: subClassOf
annotated target: erythroblast
is inferred: true

Axiom
annotated source: basophilic erythroblast
annotated property: definition
annotated target: A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721601464

Axiom
annotated source: basophilic erythroblast
annotated property: has_exact_synonym
annotated target: basophilic normoblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: basophilic erythroblast
annotated property: has_exact_synonym
annotated target: early erythroblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: basophilic erythroblast
annotated property: has_exact_synonym
annotated target: early normoblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: basophilic erythroblast
annotated property: has_exact_synonym
annotated target: prorubricyte
database_cross_reference: ISBN:0721601464

polychromatophilic erythroblast
type: Class
equivalent class: Class
  intersection of: erythroblast
  intersection of: Restriction
    on property: has part
    some values from: polychromatophilic cytoplasm
  intersection of: Restriction
    on property: has part
    some values from: GO_0000792
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000001945
subclass of: erythroblast
subclass of: Restriction
  on property: has part
  some values from: polychromatophilic cytoplasm
subclass of: Restriction
  on property: has part
  some values from: GO_0000792
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000001945
subclass of: Restriction
  on property: develops from
  some values from: basophilic erythroblast
definition: A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers.
database_cross_reference: FMA:83506
has_exact_synonym: intermediate erythroblast
has_exact_synonym: intermediate normoblast
has_exact_synonym: polychromatic erythroblast
has_exact_synonym: polychromatic normoblast
has_exact_synonym: polychromatophilic normoblast
has_exact_synonym: rubricyte

Axiom
annotated source: polychromatophilic erythroblast
annotated property: subClassOf
annotated target: erythroblast
is inferred: true

Axiom
annotated source: polychromatophilic erythroblast
annotated property: definition
annotated target: A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers.
database_cross_reference: ISBN:0721601464

Axiom
annotated source: polychromatophilic erythroblast
annotated property: has_exact_synonym
annotated target: intermediate erythroblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: polychromatophilic erythroblast
annotated property: has_exact_synonym
annotated target: intermediate normoblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: polychromatophilic erythroblast
annotated property: has_exact_synonym
annotated target: polychromatic erythroblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: polychromatophilic erythroblast
annotated property: has_exact_synonym
annotated target: polychromatic normoblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: polychromatophilic erythroblast
annotated property: has_exact_synonym
annotated target: polychromatophilic normoblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: polychromatophilic erythroblast
annotated property: has_exact_synonym
annotated target: rubricyte
database_cross_reference: ISBN:0721601464

orthochromatic erythroblast
type: Class
equivalent class: Class
  intersection of: erythroblast
  intersection of: Restriction
    on property: has part
    some values from: acidophilic cytoplasm
  intersection of: Restriction
    on property: participates in
    some values from: GO_0030263
subclass of: erythroblast
subclass of: Restriction
  on property: has part
  some values from: acidophilic cytoplasm
subclass of: Restriction
  on property: participates in
  some values from: GO_0030263
subclass of: Restriction
  on property: develops from
  some values from: polychromatophilic erythroblast
definition: The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated.
database_cross_reference: FMA:84646
has_exact_synonym: acidophilic erythroblast
has_exact_synonym: eosinophilic erythroblast
has_exact_synonym: late erythoblast
has_exact_synonym: orthochromatic normoblast
has_exact_synonym: pyknotic eto enrythroblast

Axiom
annotated source: orthochromatic erythroblast
annotated property: subClassOf
annotated target: erythroblast
is inferred: true

Axiom
annotated source: orthochromatic erythroblast
annotated property: definition
annotated target: The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated.
database_cross_reference: ISBN:0721601464

Axiom
annotated source: orthochromatic erythroblast
annotated property: has_exact_synonym
annotated target: acidophilic erythroblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: orthochromatic erythroblast
annotated property: has_exact_synonym
annotated target: eosinophilic erythroblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: orthochromatic erythroblast
annotated property: has_exact_synonym
annotated target: orthochromatic normoblast
database_cross_reference: ISBN:0721601464

Axiom
annotated source: orthochromatic erythroblast
annotated property: has_exact_synonym
annotated target: pyknotic eto enrythroblast
database_cross_reference: ISBN:0721601464

megakaryocyte progenitor cell
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: capable of
    some values from: GO_0007113
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030219
subclass of: myeloid cell
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: develops from
  some values from: megakaryocyte-erythroid progenitor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0007113
subclass of: Restriction
  on property: capable of
  some values from: GO_0030219
definition: The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0001164
database_cross_reference: CALOHA:TS-0610
database_cross_reference: FMA:84235
database_cross_reference: MESH:D055016
has_exact_synonym: CFU-Meg
has_exact_synonym: Meg-CFC
has_exact_synonym: MkP
has_exact_synonym: colony-forming unit-megakaryocyte
has_exact_synonym: megacaryoblast
has_exact_synonym: megacaryocyte progenitor cell
has_exact_synonym: megakaryoblast
has_exact_synonym: megakaryocytic progenitor cell
has related synonym: promegacaryocyte
has related synonym: promegakaryocyte
in subset: cellxgene subset
in subset: human reference atlas
comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.

Axiom
annotated source: megakaryocyte progenitor cell
annotated property: subClassOf
annotated target: myeloid lineage restricted progenitor cell
is inferred: true

Axiom
annotated source: megakaryocyte progenitor cell
annotated property: definition
annotated target: The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721601464

Axiom
annotated source: megakaryocyte progenitor cell
annotated property: has_exact_synonym
annotated target: CFU-Meg
database_cross_reference: PMID:11722431
database_cross_reference: PMID:12482498

Axiom
annotated source: megakaryocyte progenitor cell
annotated property: has_exact_synonym
annotated target: Meg-CFC
database_cross_reference: PMCID:PMC1794060

Axiom
annotated source: megakaryocyte progenitor cell
annotated property: has_exact_synonym
annotated target: MkP
database_cross_reference: PMID:21116988

Axiom
annotated source: megakaryocyte progenitor cell
annotated property: has_exact_synonym
annotated target: megakaryocytic progenitor cell
database_cross_reference: PMID:12482498

megakaryocyte
type: Class
subclass of: myeloid cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001393
subclass of: Restriction
  on property: develops from
  some values from: megakaryocyte progenitor cell
disjoint with: erythroid lineage cell
definition: A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000843
database_cross_reference: CALOHA:TS-0611
database_cross_reference: FMA:83555
has_exact_synonym: megacaryocyte
has_exact_synonym: megalocaryocyte
has_exact_synonym: megalokaryocyte
in subset: blood and immune upper slim
in subset: cellxgene subset
in subset: human reference atlas
comment: Megakaryocytes are reportedly CD181-positive and CD182-positive.

Axiom
annotated source: megakaryocyte
annotated property: subClassOf
annotated target: myeloid cell
is inferred: true

Axiom
annotated source: megakaryocyte
annotated property: definition
annotated target: A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.
database_cross_reference: ISBN:0721601464
database_cross_reference: MESH:D008533
database_cross_reference: PMID:31043076
database_cross_reference: http://en.wikipedia.org/wiki/Megakaryocyte

reticulocyte
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000001945
  intersection of: Restriction
    on property: capable of
    some values from: GO_0071971
subclass of: erythroid lineage cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000001945
subclass of: Restriction
  on property: develops from
  some values from: orthochromatic erythroblast
subclass of: Restriction
  on property: capable of
  some values from: GO_0071971
definition: An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.
database_cross_reference: BTO:0001173
database_cross_reference: CALOHA:TS-0864
database_cross_reference: MESH:D012156
in subset: blood and immune upper slim
in subset: cellxgene subset

Axiom
annotated source: reticulocyte
annotated property: subClassOf
annotated target: erythroid lineage cell
is inferred: true

Axiom
annotated source: reticulocyte
annotated property: definition
annotated target: An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm
database_cross_reference: PMID:15946868
database_cross_reference: PMID:2037622

nucleate erythrocyte
type: Class
equivalent class: Class
  intersection of: erythrocyte
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002505
subclass of: erythrocyte
subclass of: nucleate cell
subclass of: Restriction
  on property: develops from
  some values from: nucleated reticulocyte
definition: An erythrocyte having a nucleus.
has broad synonym: RBC
has broad synonym: red blood cell

Axiom
annotated source: nucleate erythrocyte
annotated property: subClassOf
annotated target: erythrocyte
is inferred: true

Axiom
annotated source: nucleate erythrocyte
annotated property: definition
annotated target: An erythrocyte having a nucleus.
database_cross_reference: GOC:add
database_cross_reference: GOc:tfm

angioblastic mesenchymal cell
type: Class
equivalent class: Class
  intersection of: mesenchymal stem cell
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000001444
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000002112
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000016043
subclass of: mesenchymal stem cell
subclass of: progenitor cell
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000001444
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000002112
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000016043
subclass of: Restriction
  on property: develops from
  some values from: mesenchymal stem cell
definition: A mesenchymal stem cell capable of developing into blood vessel endothelium.
has_exact_synonym: angioblast
has_exact_synonym: chondroplast
comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.

Axiom
annotated source: angioblastic mesenchymal cell
annotated property: subClassOf
annotated target: mesenchymal stem cell
is inferred: true

Axiom
annotated source: angioblastic mesenchymal cell
annotated property: definition
annotated target: A mesenchymal stem cell capable of developing into blood vessel endothelium.
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: PMID:12768659

cardiac mesenchymal cell
type: Class
equivalent class: Class
  intersection of: mesenchymal cell
  intersection of: Restriction
    on property: develops into
    some values from: cardiocyte
subclass of: mesenchymal cell
subclass of: CL_2000073
subclass of: Restriction
  on property: develops into
  some values from: cardiocyte
definition: A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.
in subset: cellxgene subset

Axiom
annotated source: cardiac mesenchymal cell
annotated property: definition
annotated target: A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.
database_cross_reference: PMID:18816864

retinal cone cell
type: Class
subclass of: camera-type eye photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: retinal progenitor cell
definition: One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0001036
database_cross_reference: CALOHA:TS-0866
database_cross_reference: FMA:67748
has related synonym: cone
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: retinal cone cell
annotated property: definition
annotated target: One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.
database_cross_reference: MESH:D017949

Axiom
annotated source: retinal cone cell
annotated property: hasRelatedSynonym
annotated target: cone
database_cross_reference: doi:10.1038/s41598-020-66092-9

corneal epithelial cell
type: Class
equivalent class: Class
  intersection of: squamous epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001772
subclass of: squamous epithelial cell
subclass of: general ecto-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001772
definition: An epithelial cell of the cornea.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0004298
database_cross_reference: CALOHA:TS-0173
database_cross_reference: FMA:70551
has_exact_synonym: epithelial cell of cornea
in subset: cellxgene subset
in subset: eye upper slim
in subset: human reference atlas

Axiom
annotated source: corneal epithelial cell
annotated property: definition
annotated target: An epithelial cell of the cornea.
database_cross_reference: GOC:tfm

Axiom
annotated source: corneal epithelial cell
annotated property: has_exact_synonym
annotated target: epithelial cell of cornea
database_cross_reference: FMA:70551

germ cell
type: Class
subclass of: germ line cell
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0009566
definition: The reproductive cell in multicellular organisms.
database_cross_reference: BTO:0000535
database_cross_reference: NCIT:C12597
database_cross_reference: VHOG:0001534
database_cross_reference: WBbt:0006796
in subset: cellxgene subset

Axiom
annotated source: germ cell
annotated property: subClassOf
annotated target: germ line cell
is inferred: true

Axiom
annotated source: germ cell
annotated property: definition
annotated target: The reproductive cell in multicellular organisms.
database_cross_reference: MESH:D005854

androgen secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0035935
subclass of: steroid hormone secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0035935
definition: A steroid hormone secreting cell that secretes androgen.

Axiom
annotated source: androgen secreting cell
annotated property: definition
annotated target: A steroid hormone secreting cell that secretes androgen.
database_cross_reference: GOC:tfm

retinal rod cell
type: Class
subclass of: camera-type eye photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: retinal progenitor cell
definition: One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0001024
database_cross_reference: CALOHA:TS-0870
database_cross_reference: FMA:67747
has related synonym: rod
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: retinal rod cell
annotated property: definition
annotated target: One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.
database_cross_reference: MESH:D017948

Axiom
annotated source: retinal rod cell
annotated property: hasRelatedSynonym
annotated target: rod
database_cross_reference: doi:10.1038/s41598-020-66092-9

acinar cell
type: Class
equivalent class: Class
  intersection of: glandular secretory epithelial cell
  intersection of: protein secreting cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0009842
subclass of: glandular secretory epithelial cell
subclass of: protein secreting cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0009842
definition: A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus).
database_cross_reference: FMA:83625
database_cross_reference: MESH:D061354
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000622
has_exact_synonym: acinic cell
has_exact_synonym: acinous cell
in subset: cellxgene subset

Axiom
annotated source: acinar cell
annotated property: definition
annotated target: A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus).
database_cross_reference: GOC:tfm
database_cross_reference: http://www.copewithcytokines.de

supporting cell
type: Class
subclass of: cell
definition: A cell whose primary function is to support other cell types.
database_cross_reference: BTO:0002315
has_exact_synonym: supportive cell
in subset: cellxgene subset

Axiom
annotated source: supporting cell
annotated property: definition
annotated target: A cell whose primary function is to support other cell types.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm

fenestrated endothelial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002064
subclass of: endothelial cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002064
definition: An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues.
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000666
has_exact_synonym: window cell
in subset: cellxgene subset

Axiom
annotated source: fenestrated endothelial cell
annotated property: definition
annotated target: An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues.
database_cross_reference: DOI:10.1007/978-3-211-99390-3_133

collagen secreting cell
type: Class
subclass of: extracellular matrix secreting cell
definition: An extracellular matrix secreting cell that secretes collagen.
in subset: cellxgene subset

Axiom
annotated source: collagen secreting cell
annotated property: definition
annotated target: An extracellular matrix secreting cell that secretes collagen.
database_cross_reference: GOC:tfm

primordial germ cell
type: Class
equivalent class: Class
  intersection of: germ line cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000922
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048870
subclass of: germ line cell
subclass of: motile cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000922
definition: A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.
database_cross_reference: FMA:70567
has_exact_synonym: gonocyte
has_exact_synonym: primitive germ cell
in subset: cellxgene subset

Axiom
annotated source: primordial germ cell
annotated property: subClassOf
annotated target: germ line cell
is inferred: true

Axiom
annotated source: primordial germ cell
annotated property: subClassOf
annotated target: motile cell
is inferred: true

Axiom
annotated source: primordial germ cell
annotated property: definition
annotated target: A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:1381289

female gamete
type: Class
subclass of: female germ cell
subclass of: gamete
definition: A mature sexual reproductive cell of the female germline.

Axiom
annotated source: female gamete
annotated property: subClassOf
annotated target: female germ cell
is inferred: true

Axiom
annotated source: female gamete
annotated property: definition
annotated target: A mature sexual reproductive cell of the female germline.
database_cross_reference: GOC:tfm

muscle precursor cell
type: Class
equivalent class: Class
  intersection of: precursor cell
  intersection of: Restriction
    on property: develops into
    some values from: muscle cell
subclass of: non-terminally differentiated cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: develops from
  some values from: mesodermal cell
subclass of: Restriction
  on property: develops into
  some values from: muscle cell
definition: A non-terminally differentiated cell that is capable of developing into a muscle cell.
in subset: cellxgene subset

Axiom
annotated source: muscle precursor cell
annotated property: definition
annotated target: A non-terminally differentiated cell that is capable of developing into a muscle cell.
database_cross_reference: GOC:add

PP cell
type: Class
subclass of: enteroendocrine cell
subclass of: peptide hormone secreting cell
definition: A cell that stores and secretes pancreatic polypeptide hormone.
database_cross_reference: FMA:62938
database_cross_reference: FMA:83409
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000696
has_exact_synonym: type F enteroendocrine cell
in subset: cellxgene subset

Axiom
annotated source: PP cell
annotated property: definition
annotated target: A cell that stores and secretes pancreatic polypeptide hormone.
database_cross_reference: GOC:tfm
database_cross_reference: JB:jb
database_cross_reference: PMID:15153415

neurecto-epithelial cell
type: Class
equivalent class: Class
  intersection of: ecto-epithelial cell
  intersection of: Restriction
    on property: develops from
    some values from: neurectodermal cell
subclass of: columnar/cuboidal epithelial cell
subclass of: ecto-epithelial cell
subclass of: Restriction
  on property: develops from
  some values from: neurectodermal cell
definition: Epithelial cells derived from neural plate and neural crest.
has broad synonym: neuroepithelial cell
database_cross_reference: BTO:0004301
database_cross_reference: FMA:70557
comment: The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098).

Axiom
annotated source: neurecto-epithelial cell
annotated property: definition
annotated target: Epithelial cells derived from neural plate and neural crest.
database_cross_reference: GOC:tfm

somatic stem cell
type: Class
equivalent class: Class
  intersection of: stem cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048103
subclass of: stem cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0048103
definition: A stem cell that can give rise to cell types of the body other than those of the germ-line.
database_cross_reference: CALOHA:TS-2086
database_cross_reference: MESH:D053687

Axiom
annotated source: somatic stem cell
annotated property: definition
annotated target: A stem cell that can give rise to cell types of the body other than those of the germ-line.
database_cross_reference: GO:0048103

striated muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: has part
    some values from: GO_0030017
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001410
subclass of: muscle cell
subclass of: Restriction
  on property: has part
  some values from: GO_0030017
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001410
disjoint with: non-striated muscle cell
definition: Muscle cell which has as its direct parts myofilaments organized into sarcomeres.
database_cross_reference: BTO:0002916
database_cross_reference: CALOHA:TS-2157
database_cross_reference: FMA:86936

Axiom
annotated source: striated muscle cell
annotated property: definition
annotated target: Muscle cell which has as its direct parts myofilaments organized into sarcomeres.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

leukocyte
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002505
  intersection of: Restriction
    on property: capable of
    some values from: GO_0001667
subclass of: motile cell
subclass of: eukaryotic cell
subclass of: hematopoietic cell
subclass of: nucleate cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002405
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon 7742
subclass of: Restriction
  on property: develops from
  some values from: hematopoietic stem cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0001667
definition: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000751
database_cross_reference: CALOHA:TS-0549
database_cross_reference: FMA:62852
database_cross_reference: MESH:D007962
database_cross_reference: NCIT:C12529
has_exact_synonym: leucocyte
has_exact_synonym: white blood cell
has related synonym: immune cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: leukocyte
annotated property: subClassOf
annotated target: hematopoietic cell
is inferred: true

Axiom
annotated source: leukocyte
annotated property: definition
annotated target: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:978-0-323-05290-0

retinal ganglion cell
type: Class
subclass of: neuron
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0000966
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0001800
database_cross_reference: FMA:67765
database_cross_reference: MESH:D012165
has_exact_synonym: gangliocyte
has_exact_synonym: ganglion cell of retina
has related synonym: RGC
has related synonym: RGCs
in subset: cellxgene subset
in subset: eye upper slim
in subset: human reference atlas

Axiom
annotated source: retinal ganglion cell
annotated property: definition
annotated target: The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.
database_cross_reference: GOC:dph

Axiom
annotated source: retinal ganglion cell
annotated property: hasRelatedSynonym
annotated target: RGC
database_cross_reference: doi:10.1038/s41598-020-66092-9
has synonym type: OMO_0003000

Axiom
annotated source: retinal ganglion cell
annotated property: hasRelatedSynonym
annotated target: RGCs
database_cross_reference: doi:10.1038/s41598-020-66092-9
has synonym type: OMO_0003000
has synonym type: OMO_0003004

cardiac muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007100
  intersection of: Restriction
    on property: has part
    some values from: GO_0030017
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002478
  intersection of: Restriction
    on property: participates in
    some values from: GO_0060047
subclass of: striated muscle cell
subclass of: cardiocyte
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002478
subclass of: Restriction
  on property: participates in
  some values from: GO_0060047
subclass of: Restriction
  on property: develops from
  some values from: cardiac muscle myoblast
definition: Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.
RO_0002175: NCBITaxon 9606
has broad synonym: cardiocyte
database_cross_reference: BTO:0001539
database_cross_reference: CALOHA:TS-0115
database_cross_reference: FMA:14067
database_cross_reference: MESH:D032383
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0000746
has_exact_synonym: cardiac muscle fiber
has_exact_synonym: cardiac myocyte
has_exact_synonym: cardiomyocyte
has_exact_synonym: heart muscle cell
in subset: cellxgene subset
in subset: general cell types upper slim
in subset: human reference atlas
comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.

Axiom
annotated source: cardiac muscle cell
annotated property: definition
annotated target: Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.
database_cross_reference: GOC:mtg_cardiacconduct_nov11
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0323052908
database_cross_reference: PMID:22426062
database_cross_reference: PMID:4711263

Axiom
annotated source: cardiac muscle cell
annotated property: has_exact_synonym
annotated target: cardiac muscle fiber
database_cross_reference: GO:0048739

myeloid cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: develops from
    some values from: common myeloid progenitor
subclass of: eukaryotic cell
subclass of: hematopoietic cell
subclass of: Restriction
  on property: develops from
  some values from: common myeloid progenitor
definition: A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.
database_cross_reference: BTO:0001441
database_cross_reference: CALOHA:TS-0647
database_cross_reference: MESH:D022423
in subset: cellxgene subset

Axiom
annotated source: myeloid cell
annotated property: subClassOf
annotated target: hematopoietic cell
is inferred: true

Axiom
annotated source: myeloid cell
annotated property: definition
annotated target: A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.
database_cross_reference: GOC:add

erythroid lineage cell
type: Class
subclass of: myeloid cell
definition: A immature or mature cell in the lineage leading to and including erythrocytes.
RO_0002175: NCBITaxon 9606
database_cross_reference: CALOHA:TS-0290
database_cross_reference: FMA:62845
database_cross_reference: FMA:83516
has_exact_synonym: erythropoietic cell
in subset: cellxgene subset
in subset: human reference atlas
comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes.

Axiom
annotated source: erythroid lineage cell
annotated property: definition
annotated target: A immature or mature cell in the lineage leading to and including erythrocytes.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm

erythroblast
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: has part
    some values from: GO_0005634
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0005730
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030218
subclass of: erythroid lineage cell
subclass of: progenitor cell
subclass of: Restriction
  on property: has part
  some values from: GO_0005634
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0005730
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: develops from
  some values from: proerythroblast
subclass of: Restriction
  on property: capable of
  some values from: GO_0030218
definition: A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.
database_cross_reference: BTO:0001571
database_cross_reference: CALOHA:TS-0289
database_cross_reference: FMA:83504
database_cross_reference: MESH:D004900
has_exact_synonym: normoblast
in subset: blood and immune upper slim
in subset: cellxgene subset

Axiom
annotated source: erythroblast
annotated property: subClassOf
annotated target: erythroid lineage cell
is inferred: true

Axiom
annotated source: erythroblast
annotated property: definition
annotated target: A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.
database_cross_reference: GOC:add
database_cross_reference: ISBN:0721601464
database_cross_reference: PMID:18174176

myeloid leukocyte
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: develops from
    some values from: common myeloid progenitor
subclass of: leukocyte
subclass of: myeloid cell
definition: A cell of the monocyte, granulocyte, or mast cell lineage.
in subset: cellxgene subset

Axiom
annotated source: myeloid leukocyte
annotated property: subClassOf
annotated target: leukocyte
is inferred: true

Axiom
annotated source: myeloid leukocyte
annotated property: definition
annotated target: A cell of the monocyte, granulocyte, or mast cell lineage.
database_cross_reference: GOC:add

hematopoietic multipotent progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001402
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000001003
subclass of: eukaryotic cell
subclass of: hematopoietic precursor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001402
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000001003
subclass of: Restriction
  on property: develops from
  some values from: hematopoietic stem cell
disjoint with: hematopoietic oligopotent progenitor cell
definition: A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.
RO_0002175: NCBITaxon 9606
database_cross_reference: BTO:0000725
database_cross_reference: CALOHA:TS-0448
has_exact_synonym: MPP
has_exact_synonym: hemopoietic progenitor cell
in subset: blood and immune upper slim
in subset: cellxgene subset
in subset: human reference atlas
comment: Markers differ between mouse and human.

Axiom
annotated source: hematopoietic multipotent progenitor cell
annotated property: definition
annotated target: A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19022770

myeloid lineage restricted progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic lineage restricted progenitor cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030099
subclass of: hematopoietic lineage restricted progenitor cell
subclass of: progenitor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0030099
definition: A progenitor cell restricted to the myeloid lineage.
RO_0002175: NCBITaxon 9606
has broad synonym: myeloid progenitor cell
database_cross_reference: BTO:0004730
database_cross_reference: CALOHA:TS-2099
database_cross_reference: FMA:70339
in subset: cellxgene subset
in subset: human reference atlas
comment: Note that this is a class of cell types, not an identified single cell type.

Axiom
annotated source: myeloid lineage restricted progenitor cell
annotated property: subClassOf
annotated target: hematopoietic lineage restricted progenitor cell
is inferred: true

Axiom
annotated source: myeloid lineage restricted progenitor cell
annotated property: definition
annotated target: A progenitor cell restricted to the myeloid lineage.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19022770

serotonergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0060096
subclass of: serotonin secreting cell
subclass of: neuron
subclass of: Restriction
  on property: capable of
  some values from: GO_0060096
definition: A neuron that releases serotonin as a neurotransmitter.
database_cross_reference: MESH:D059326
database_cross_reference: WBbt:0006837
has_exact_synonym: 5-HT neuron
has_exact_synonym: 5-hydroxytryptamine neuron
has related synonym: serotinergic neuron

Axiom
annotated source: serotonergic neuron
annotated property: definition
annotated target: A neuron that releases serotonin as a neurotransmitter.
database_cross_reference: SANBI:mhl

hematopoietic cell
type: Class
subclass of: cell
definition: A cell of a hematopoietic lineage.
database_cross_reference: BTO:0000574
database_cross_reference: CALOHA:TS-2017
database_cross_reference: FMA:70366
database_cross_reference: FMA:83598
has_exact_synonym: haematopoietic cell
has_exact_synonym: haemopoietic cell
has_exact_synonym: hemopoietic cell
in subset: cellxgene subset

Axiom
annotated source: hematopoietic cell
annotated property: definition
annotated target: A cell of a hematopoietic lineage.
database_cross_reference: GOC:add
database_cross_reference: GO_REF:0000031

bone cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001474
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001474
definition: A connective tissue cell found in bone.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0001-9990-8331
creation date: 2011-11-16T04:28:16Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0001035
in subset: general cell types upper slim
in subset: human reference atlas

Axiom
annotated source: bone cell
annotated property: definition
annotated target: A connective tissue cell found in bone.
database_cross_reference: GOC:add
database_cross_reference: GO_REF:0000034

hematopoietic oligopotent progenitor cell, lineage-negative
type: Class
equivalent class: Class
  intersection of: hematopoietic oligopotent progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001401
subclass of: hematopoietic oligopotent progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
definition: A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-01-06T03:43:27Z

Axiom
annotated source: hematopoietic oligopotent progenitor cell, lineage-negative
annotated property: definition
annotated target: A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19022770

erythroid progenitor cell, mammalian
type: Class
equivalent class: Class
  intersection of: erythroid progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: has plasma membrane part
    some values from: PR_000001945
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030218
subclass of: erythroid progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: has plasma membrane part
  some values from: PR_000001945
subclass of: Restriction
  on property: capable of
  some values from: GO_0030218
definition: A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).
database_cross_reference: BTO:0004911
has related synonym: BFU-E
has related synonym: CFU-E
has related synonym: blast forming unit erythroid
has related synonym: burst forming unit erythroid
has related synonym: colony forming unit erythroid
has related synonym: erythroid stem cell
in subset: cellxgene subset

Axiom
annotated source: erythroid progenitor cell, mammalian
annotated property: definition
annotated target: A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).
database_cross_reference: GOC:add
database_cross_reference: ISBN:0721601464

Axiom
annotated source: erythroid progenitor cell, mammalian
annotated property: hasRelatedSynonym
annotated target: BFU-E
has synonym type: OMO_0003000

Axiom
annotated source: erythroid progenitor cell, mammalian
annotated property: hasRelatedSynonym
annotated target: CFU-E
has synonym type: OMO_0003000

hematopoietic lineage restricted progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001400
subclass of: eukaryotic cell
subclass of: hematopoietic precursor cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001400
subclass of: Restriction
  on property: develops from
  some values from: hematopoietic oligopotent progenitor cell
disjoint with: hematopoietic oligopotent progenitor cell
definition: A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-01-06T03:43:20Z
in subset: blood and immune upper slim

Axiom
annotated source: hematopoietic lineage restricted progenitor cell
annotated property: definition
annotated target: A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19022770

hematopoietic oligopotent progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001401
subclass of: eukaryotic cell
subclass of: hematopoietic precursor cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001401
subclass of: Restriction
  on property: develops from
  some values from: hematopoietic multipotent progenitor cell
definition: A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-01-06T03:43:27Z
in subset: blood and immune upper slim
comment: This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060).

Axiom
annotated source: hematopoietic oligopotent progenitor cell
annotated property: definition
annotated target: A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19022770
database_cross_reference: https://orcid.org/0000-0001-5208-3432

pancreatic acinar cell
type: Class
equivalent class: Class
  intersection of: acinar cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001263
subclass of: acinar cell
subclass of: CL_1001599
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001263
subclass of: Restriction
  on property: has part
  some values from: GO_0042589
definition: A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-24T03:16:29Z
database_cross_reference: BTO:0000028
database_cross_reference: CALOHA:TS-0737
database_cross_reference: FMA:63032
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002064
has_exact_synonym: acinar cell of pancreas
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: pancreatic acinar cell
annotated property: subClassOf
annotated target: acinar cell
is inferred: true

Axiom
annotated source: pancreatic acinar cell
annotated property: definition
annotated target: A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: PMID:20395539
database_cross_reference: http://www.copewithcytokines.de/cope.cgi

type A enteroendocrine cell
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070091
subclass of: enteroendocrine cell
subclass of: glucagon secreting cell
definition: An enteroendocrine cell that produces glucagon.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-10T10:48:54Z
database_cross_reference: FMA:62939
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002067
in subset: cellxgene subset

Axiom
annotated source: type A enteroendocrine cell
annotated property: definition
annotated target: An enteroendocrine cell that produces glucagon.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0412046911

Purkinje myocyte
type: Class
subclass of: specialized cardiac myocyte
definition: Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-28T08:36:15Z
database_cross_reference: BTO:0001032
database_cross_reference: FMA:14146
has_exact_synonym: Purkinje cell fiber
has_exact_synonym: Purkinje muscle cell
has_exact_synonym: myocytus conducens cardiacus
in subset: human reference atlas

Axiom
annotated source: Purkinje myocyte
annotated property: definition
annotated target: Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter.
database_cross_reference: FMA:0412046911
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19939742

nodal myocyte
type: Class
subclass of: specialized cardiac myocyte
definition: A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-29T11:41:37Z
has broad synonym: pacemaker cell
database_cross_reference: BTO:0004190
database_cross_reference: FMA:67101
has_exact_synonym: P cell
has_exact_synonym: cardiac pacemaker cell
has_exact_synonym: myocytus nodalis

Axiom
annotated source: nodal myocyte
annotated property: definition
annotated target: A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery.
database_cross_reference: FMA:67101
database_cross_reference: GOC:tfm

Axiom
annotated source: nodal myocyte
annotated property: has_exact_synonym
annotated target: cardiac pacemaker cell
database_cross_reference: GOC:pr

transitional myocyte
type: Class
subclass of: specialized cardiac myocyte
definition: Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-29T02:39:32Z
database_cross_reference: FMA:67142

Axiom
annotated source: transitional myocyte
annotated property: definition
annotated target: Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes.
database_cross_reference: FMA:67142
database_cross_reference: GOC:tfm

myocardial endocrine cell
type: Class
subclass of: endocrine cell
subclass of: specialized cardiac myocyte
definition: The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides).
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-29T11:50:47Z
database_cross_reference: FMA:67111

Axiom
annotated source: myocardial endocrine cell
annotated property: definition
annotated target: The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides).
database_cross_reference: FMA:67111
database_cross_reference: GOC:tfm

endo-epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: develops from
    some values from: endodermal cell
subclass of: epithelial cell
subclass of: Restriction
  on property: develops from
  some values from: endodermal cell
definition: An epithelial cell derived from endoderm.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-29T03:38:14Z
database_cross_reference: FMA:69075
in subset: cellxgene subset

Axiom
annotated source: endo-epithelial cell
annotated property: definition
annotated target: An epithelial cell derived from endoderm.
database_cross_reference: FMA:69075
database_cross_reference: GOC:tfm

ecto-epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: develops from
    some values from: ectodermal cell
subclass of: epithelial cell
subclass of: Restriction
  on property: develops from
  some values from: ectodermal cell
definition: An epithelial cell derived from ectoderm.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-29T03:38:22Z
database_cross_reference: FMA:69074

Axiom
annotated source: ecto-epithelial cell
annotated property: definition
annotated target: An epithelial cell derived from ectoderm.
database_cross_reference: FMA:69074
database_cross_reference: GOC:tfm

meso-epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: develops from
    some values from: mesodermal cell
subclass of: epithelial cell
subclass of: Restriction
  on property: develops from
  some values from: mesodermal cell
definition: Epithelial cell derived from mesoderm or mesenchyme.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-29T03:49:14Z
database_cross_reference: FMA:69076
has_exact_synonym: epithelial mesenchymal cell

Axiom
annotated source: meso-epithelial cell
annotated property: definition
annotated target: Epithelial cell derived from mesoderm or mesenchyme.
database_cross_reference: FMA:69076
database_cross_reference: GOC:tfm

pancreatic ductal cell
type: Class
equivalent class: Class
  intersection of: epithelial cell of pancreas
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001064
  intersection of: Restriction
    on property: capable of
    some values from: GO_0015106
subclass of: branched duct epithelial cell
subclass of: CL_1001433
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001064
subclass of: Restriction
  on property: capable of
  some values from: GO_0015106
definition: Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-30T08:49:43Z
database_cross_reference: FMA:63099
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: pancreatic ductal cell
annotated property: definition
annotated target: Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH.
database_cross_reference: FMA:63099
database_cross_reference: GOC:tfm
database_cross_reference: PMID:14740223

pancreatic centro-acinar cell
type: Class
equivalent class: Class
  intersection of: epithelial cell of pancreas
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001263
  intersection of: Restriction
    on property: capable of
    some values from: GO_0015106
subclass of: CL_1001433
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001263
subclass of: Restriction
  on property: capable of
  some values from: GO_0015106
definition: A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-06-30T08:49:52Z
database_cross_reference: FMA:62455
has_exact_synonym: centroacinar cell of Langerhans
has_exact_synonym: pancreatic centroacinar cell
in subset: human reference atlas

Axiom
annotated source: pancreatic centro-acinar cell
annotated property: definition
annotated target: A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:12142741
database_cross_reference: PMID:20018761
database_cross_reference: PMID:8185160

specialized cardiac myocyte
type: Class
subclass of: cardiac muscle cell
definition: A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-07-21T01:33:38Z
database_cross_reference: FMA:67968

Axiom
annotated source: specialized cardiac myocyte
annotated property: definition
annotated target: A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart.
database_cross_reference: FMA:67968
database_cross_reference: GOC:tfm

nongranular leukocyte
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0030141
subclass of: leukocyte
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0030141
definition: A leukocyte that lacks granules.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-07-22T11:30:33Z
database_cross_reference: FMA:62855
has_exact_synonym: agranular leukocyte
in subset: blood and immune upper slim

Axiom
annotated source: nongranular leukocyte
annotated property: subClassOf
annotated target: leukocyte
is inferred: true

Axiom
annotated source: nongranular leukocyte
annotated property: definition
annotated target: A leukocyte that lacks granules.
database_cross_reference: GOC:tfm

interstitial cell of Cajal
type: Class
equivalent class: Class
  intersection of: neurecto-epithelial cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0043134
subclass of: neurecto-epithelial cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0043134
definition: This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-07-22T03:26:00Z
database_cross_reference: BTO:0003914
database_cross_reference: FMA:86573
has_exact_synonym: ICC
has_exact_synonym: intestinal pacemaker cell
in subset: cellxgene subset
in subset: human reference atlas
comment: Some argue this cell type is of mesenchymal origin.

Axiom
annotated source: interstitial cell of Cajal
annotated property: subClassOf
annotated target: neurecto-epithelial cell
is inferred: true

Axiom
annotated source: interstitial cell of Cajal
annotated property: definition
annotated target: This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:16460275
database_cross_reference: PMID:19520112

Axiom
annotated source: interstitial cell of Cajal
annotated property: has_exact_synonym
annotated target: intestinal pacemaker cell
database_cross_reference: GOC:pr

bone marrow cell
type: Class
equivalent class: Class
  intersection of: bone cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002371
subclass of: bone cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002371
definition: A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-07-22T04:48:15Z
database_cross_reference: BTO:0004850
database_cross_reference: FMA:83621
database_cross_reference: MESH:D001854
in subset: cellxgene subset
comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense.

Axiom
annotated source: bone marrow cell
annotated property: subClassOf
annotated target: bone cell
is inferred: true

Axiom
annotated source: bone marrow cell
annotated property: definition
annotated target: A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256

hilus cell of ovary
type: Class
subclass of: androgen secreting cell
subclass of: stromal cell of ovary
definition: A cell in the hilum of the ovary that produces androgens.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-23T11:18:18Z
database_cross_reference: FMA:18710
has_exact_synonym: hilar cell of ovary
in subset: human reference atlas

Axiom
annotated source: hilus cell of ovary
annotated property: definition
annotated target: A cell in the hilum of the ovary that produces androgens.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:068340007X

stromal cell of ovary
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000992
subclass of: stromal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000992
definition: A stomal cell of the ovary
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-23T12:10:31Z
database_cross_reference: FMA:72299
has_exact_synonym: ovarian stromal cell
in subset: cellxgene subset

Axiom
annotated source: stromal cell of ovary
annotated property: definition
annotated target: A stomal cell of the ovary
database_cross_reference: GOC:tfm

Axiom
annotated source: stromal cell of ovary
annotated property: has_exact_synonym
annotated target: ovarian stromal cell
database_cross_reference: GOC:cjm

endothelial cell of vascular tree
type: Class
subclass of: endothelial cell
definition: An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-24T02:06:40Z
database_cross_reference: BTO:0001854
database_cross_reference: CALOHA:TS-1106
database_cross_reference: FMA:67755
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002139
has_exact_synonym: vascular endothelial cell
has narrow synonym: cubodial endothelial cell of vascular tree
in subset: cellxgene subset
comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive.

Axiom
annotated source: endothelial cell of vascular tree
annotated property: definition
annotated target: An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: PMID:12768659

capillary endothelial cell
type: Class
equivalent class: Class
  intersection of: blood vessel endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001915
subclass of: squamous endothelial cell
subclass of: CL_2000008
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001915
definition: An endothelial cell found in capillaries.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-24T10:15:00Z
database_cross_reference: BTO:0004956
database_cross_reference: CALOHA:TS-0112
database_cross_reference: FMA:67756
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: capillary endothelial cell
annotated property: definition
annotated target: An endothelial cell found in capillaries.
database_cross_reference: GOC:tfm

general ecto-epithelial cell
type: Class
subclass of: ecto-epithelial cell
definition: Epithelial cells derived from general body ectoderm and ectoderm placodes.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-26T08:31:08Z
database_cross_reference: FMA:70556

Axiom
annotated source: general ecto-epithelial cell
annotated property: definition
annotated target: Epithelial cells derived from general body ectoderm and ectoderm placodes.
database_cross_reference: GOC:tfm

epithelial cell of stomach
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001276
subclass of: epithelial cell of alimentary canal
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001276
definition: An epithelial cell found in the lining of the stomach.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-25T03:22:08Z
database_cross_reference: FMA:62948

Axiom
annotated source: epithelial cell of stomach
annotated property: subClassOf
annotated target: epithelial cell of alimentary canal
is inferred: true

Axiom
annotated source: epithelial cell of stomach
annotated property: definition
annotated target: An epithelial cell found in the lining of the stomach.
database_cross_reference: GOC:tfm

mucous cell of stomach
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001276
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070254
subclass of: mucus secreting cell
subclass of: epithelial cell of stomach
subclass of: CL_1100001
definition: An epithelial cell of the stomach. This cell produces mucous.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-25T03:38:51Z
database_cross_reference: FMA:63464

Axiom
annotated source: mucous cell of stomach
annotated property: definition
annotated target: An epithelial cell of the stomach. This cell produces mucous.
database_cross_reference: GOC:tfm

stem cell of gastric gland
type: Class
equivalent class: Class
  intersection of: multi fate stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000325
subclass of: multi fate stem cell
subclass of: epithelial cell of stomach
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000325
definition: A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-25T03:57:08Z
database_cross_reference: FMA:62953

Axiom
annotated source: stem cell of gastric gland
annotated property: subClassOf
annotated target: multi fate stem cell
is inferred: true

Axiom
annotated source: stem cell of gastric gland
annotated property: definition
annotated target: A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651

hepatic stem cell
type: Class
equivalent class: Class
  intersection of: multi fate stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002107
subclass of: multi fate stem cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002107
definition: A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes).
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-08-30T02:00:42Z
database_cross_reference: FMA:86577
has related synonym: HpSC

Axiom
annotated source: hepatic stem cell
annotated property: subClassOf
annotated target: multi fate stem cell
is inferred: true

Axiom
annotated source: hepatic stem cell
annotated property: definition
annotated target: A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes).
database_cross_reference: GOC:tfm
database_cross_reference: PMID:26798363

Axiom
annotated source: hepatic stem cell
annotated property: hasRelatedSynonym
annotated target: HpSC
database_cross_reference: PMID:18442648
has synonym type: OMO_0003000

epithelial cell of tracheobronchial tree
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0008397
subclass of: epithelial cell of lower respiratory tract
subclass of: Restriction
  on property: part of
  some values from: UBERON_0008397
definition: An epithelial cell of the tracheobronchial tree.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-02T02:09:14Z
database_cross_reference: FMA:66816

Axiom
annotated source: epithelial cell of tracheobronchial tree
annotated property: definition
annotated target: An epithelial cell of the tracheobronchial tree.
database_cross_reference: GOC:tfm

intermediate epitheliocyte
type: Class
subclass of: epithelial cell of tracheobronchial tree
definition: An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-02T02:53:59Z
database_cross_reference: FMA:69060
has_exact_synonym: undifferentiated columnar cell of tracheobronchial tree

Axiom
annotated source: intermediate epitheliocyte
annotated property: definition
annotated target: An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651

vertebrate lens cell
type: Class
subclass of: epithelial cell
subclass of: crystallin accumulating cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000965
definition: A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-07T10:38:03Z
database_cross_reference: FMA:70950
in subset: eye upper slim

Axiom
annotated source: vertebrate lens cell
annotated property: definition
annotated target: A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

lens epithelial cell
type: Class
equivalent class: Class
  intersection of: columnar/cuboidal epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001803
subclass of: columnar/cuboidal epithelial cell
subclass of: vertebrate lens cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001803
definition: A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-07T10:45:47Z
database_cross_reference: FMA:67559
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: lens epithelial cell
annotated property: subClassOf
annotated target: columnar/cuboidal epithelial cell
is inferred: true

Axiom
annotated source: lens epithelial cell
annotated property: definition
annotated target: A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
database_cross_reference: http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium

marrow fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002371
subclass of: fibroblast
subclass of: stromal cell of bone marrow
definition: A fibroblast in the bone marrow.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-07T02:25:18Z
database_cross_reference: FMA:84377

Axiom
annotated source: marrow fibroblast
annotated property: definition
annotated target: A fibroblast in the bone marrow.
database_cross_reference: GOC:tfm

nucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002505
subclass of: cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002505
definition: A cell containing at least one nucleus.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-07T03:32:33Z
database_cross_reference: FMA:67513

Axiom
annotated source: nucleate cell
annotated property: definition
annotated target: A cell containing at least one nucleus.
database_cross_reference: GOC:tfm

smooth muscle cell of sphincter of pupil
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001607
subclass of: sphincter associated smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001607
subclass of: Restriction
  on property: develops from
  some values from: neurectodermal cell
definition: A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-08T08:53:42Z
database_cross_reference: FMA:70611
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002243
has_exact_synonym: smooth muscle fiber of sphincter of pupil
has related synonym: smooth muscle fibre of sphincter of pupil
in subset: cellxgene subset

Axiom
annotated source: smooth muscle cell of sphincter of pupil
annotated property: subClassOf
annotated target: sphincter associated smooth muscle cell
is inferred: true

Axiom
annotated source: smooth muscle cell of sphincter of pupil
annotated property: definition
annotated target: A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
database_cross_reference: ISBN:0721694128

peripheral blood stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000178
subclass of: hematopoietic stem cell
subclass of: circulating cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000178
definition: A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells).
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-07T03:57:09Z
database_cross_reference: BTO:0002669
database_cross_reference: FMA:86711
database_cross_reference: MESH:D000072916
has_exact_synonym: PBSC

Axiom
annotated source: peripheral blood stem cell
annotated property: subClassOf
annotated target: hematopoietic stem cell
is inferred: true

Axiom
annotated source: peripheral blood stem cell
annotated property: definition
annotated target: A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells).
database_cross_reference: GOC:tfm

intestinal crypt stem cell
type: Class
equivalent class: Class
  intersection of: stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001983
subclass of: multi fate stem cell
subclass of: intestinal epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001983
definition: A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-08T09:21:22Z
database_cross_reference: FMA:63379
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002250
has_exact_synonym: stem cell of intestinal crypt of Lieberkuhn
in subset: cellxgene subset

Axiom
annotated source: intestinal crypt stem cell
annotated property: definition
annotated target: A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651

epithelial cell of alimentary canal
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0003929
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0003929
definition: An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-08T09:26:53Z

Axiom
annotated source: epithelial cell of alimentary canal
annotated property: definition
annotated target: An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

epithelial cell of esophagus
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001976
subclass of: epithelial cell of alimentary canal
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001976
definition: An epithelial cell of the lining of the esophagus.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-08T09:28:20Z
database_cross_reference: FMA:63071
in subset: cellxgene subset

Axiom
annotated source: epithelial cell of esophagus
annotated property: subClassOf
annotated target: epithelial cell of alimentary canal
is inferred: true

Axiom
annotated source: epithelial cell of esophagus
annotated property: definition
annotated target: An epithelial cell of the lining of the esophagus.
database_cross_reference: GOC:tfm

epithelial cell of large intestine
type: Class
equivalent class: Class
  intersection of: intestinal epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000059
subclass of: intestinal epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001278
definition: An epithelial cell of the lining of the large intestine.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-08T09:28:22Z
database_cross_reference: BTO:0004297
database_cross_reference: FMA:256157
has related synonym: epithelial cell of colon
in subset: cellxgene subset

Axiom
annotated source: epithelial cell of large intestine
annotated property: subClassOf
annotated target: intestinal epithelial cell
is inferred: true

Axiom
annotated source: epithelial cell of large intestine
annotated property: definition
annotated target: An epithelial cell of the lining of the large intestine.
database_cross_reference: GOC:tfm

epithelial cell of small intestine
type: Class
equivalent class: Class
  intersection of: intestinal epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002108
subclass of: intestinal epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002108
definition: An epithelial cell of the lining of the small intestine.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-08T09:41:46Z
database_cross_reference: FMA:256159
in subset: cellxgene subset

Axiom
annotated source: epithelial cell of small intestine
annotated property: subClassOf
annotated target: intestinal epithelial cell
is inferred: true

Axiom
annotated source: epithelial cell of small intestine
annotated property: definition
annotated target: An epithelial cell of the lining of the small intestine.
database_cross_reference: GOC:tfm

endothelial cell of sinusoid
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0003909
subclass of: blood vessel endothelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0003909
definition: An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-14T10:57:26Z
database_cross_reference: FMA:63134
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002262
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: endothelial cell of sinusoid
annotated property: definition
annotated target: An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256

type A cell of stomach
type: Class
equivalent class: Class
  intersection of: type A enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001276
subclass of: type A enteroendocrine cell
subclass of: CL_1001517
definition: A type of enteroendocrine cell found in the stomach that secretes glucagon.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-10T10:54:42Z
database_cross_reference: FMA:83411

Axiom
annotated source: type A cell of stomach
annotated property: definition
annotated target: A type of enteroendocrine cell found in the stomach that secretes glucagon.
database_cross_reference: GOC:tfm

type D cell of colon
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001155
subclass of: type D enteroendocrine cell
subclass of: enteroendocrine cell of colon
subclass of: CL_1001588
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: A D cell located in the colon.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-10T11:37:35Z
database_cross_reference: FMA:268744
has_exact_synonym: colon D-cell
has_exact_synonym: colonic delta cell
has_exact_synonym: delta cell of colon

Axiom
annotated source: type D cell of colon
annotated property: definition
annotated target: A D cell located in the colon.
database_cross_reference: GOC:tfm

type D cell of small intestine
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002108
subclass of: type D enteroendocrine cell
subclass of: enteroendocrine cell of small intestine
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: A type D cell of the small intestine.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-10T01:34:22Z
database_cross_reference: FMA:268736
has_exact_synonym: delta cell of small intestine
has_exact_synonym: small intestine D-cell
has_exact_synonym: small intestine delta cell

Axiom
annotated source: type D cell of small intestine
annotated property: definition
annotated target: A type D cell of the small intestine.
database_cross_reference: GOC:tfm

type D cell of stomach
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001276
subclass of: type D enteroendocrine cell
subclass of: glandular epithelial cell of stomach
subclass of: stomach neuroendocrine cell
definition: A type D cell found in the stomach.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-10T01:36:03Z
database_cross_reference: FMA:83410
has_exact_synonym: delta cell of stomach
has_exact_synonym: stomach D-cell
has_exact_synonym: stomach delta cell

Axiom
annotated source: type D cell of stomach
annotated property: definition
annotated target: A type D cell found in the stomach.
database_cross_reference: GOC:tfm

pancreatic PP cell
type: Class
equivalent class: Class
  intersection of: PP cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000006
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: PP cell
subclass of: pancreatic endocrine cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000006
definition: A PP cell located in the islets of the pancreas.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-10T03:30:31Z
database_cross_reference: BTO:0000805
database_cross_reference: FMA:70588
database_cross_reference: MESH:D050418
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002275
has_exact_synonym: PP cell of pancreatic islet
has_exact_synonym: PP-cell of pancreatic islet
has_exact_synonym: pancreatic polypeptide-secreting cell
in subset: cellxgene subset
in subset: human reference atlas
comment: The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell.

Axiom
annotated source: pancreatic PP cell
annotated property: definition
annotated target: A PP cell located in the islets of the pancreas.
database_cross_reference: GOC:tfm

epithelial cell of skin gland
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002419
subclass of: general ecto-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002419
definition: An epithelial cell of a skin gland.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-14T12:00:07Z
database_cross_reference: FMA:70657
has_exact_synonym: epithelial cell of gland of skin

Axiom
annotated source: epithelial cell of skin gland
annotated property: definition
annotated target: An epithelial cell of a skin gland.
database_cross_reference: GOC:tfm

neural cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001016
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001016
definition: A cell that is part of the nervous system.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-15T01:34:57Z
database_cross_reference: CALOHA:TS-2040
database_cross_reference: FMA:70333
in subset: cellxgene subset

Axiom
annotated source: neural cell
annotated property: definition
annotated target: A cell that is part of the nervous system.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256

connective tissue cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002384
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002384
definition: A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-15T03:01:54Z
database_cross_reference: CALOHA:TS-2096
database_cross_reference: FMA:63875
database_cross_reference: MESH:D003239
in subset: cellxgene subset

Axiom
annotated source: connective tissue cell
annotated property: definition
annotated target: A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256

embryonic cell (metazoa)
type: Class
subclass of: cell
definition: A cell of the embryo.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-15T03:39:21Z
database_cross_reference: CALOHA:TS-0263
database_cross_reference: FMA:82840
database_cross_reference: WBbt:0007028
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002321

Axiom
annotated source: embryonic cell (metazoa)
annotated property: definition
annotated target: A cell of the embryo.
database_cross_reference: FMA:0618947256

bronchial epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002185
subclass of: epithelial cell of tracheobronchial tree
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002031
definition: An epithelial cell of the bronchus.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-20T02:00:00Z
database_cross_reference: BTO:0002922
in subset: cellxgene subset

Axiom
annotated source: bronchial epithelial cell
annotated property: definition
annotated target: An epithelial cell of the bronchus.
database_cross_reference: GOC:tfm

neural crest derived adipocyte
type: Class
equivalent class: Class
  intersection of: adipocyte
  intersection of: Restriction
    on property: develops from
    some values from: migratory neural crest cell
subclass of: adipocyte
subclass of: Restriction
  on property: develops from
  some values from: neural crest derived fibroblast
definition: An adipocyte derived from a neural crest cell.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-20T02:25:25Z

Axiom
annotated source: neural crest derived adipocyte
annotated property: definition
annotated target: An adipocyte derived from a neural crest cell.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:17507398

endocardial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002165
subclass of: cardiac endothelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002165
definition: An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-21T04:33:05Z
database_cross_reference: FMA:75621
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002350
has_exact_synonym: endocardial endothelial cell
has_exact_synonym: endothelial cell of endocardium
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: endocardial cell
annotated property: definition
annotated target: An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin.
database_cross_reference: GOC:tfm
database_cross_reference: ISSN:0452-3458

Axiom
annotated source: endocardial cell
annotated property: has_exact_synonym
annotated target: endothelial cell of endocardium
database_cross_reference: FMA:75621

progenitor cell of endocrine pancreas
type: Class
subclass of: progenitor cell
definition: A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-21T04:41:06Z
has_exact_synonym: pancreatic endocrine progenitor
has_exact_synonym: pancreatic islet progenitor cell
in subset: cellxgene subset

Axiom
annotated source: progenitor cell of endocrine pancreas
annotated property: definition
annotated target: A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:20025937
database_cross_reference: PMID:20217494
database_cross_reference: PMID:22728667

gestational hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000922
subclass of: hematopoietic stem cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000922
definition: A hematopoietic stem cell that exists during embryogenesis.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-22T09:05:13Z

Axiom
annotated source: gestational hematopoietic stem cell
annotated property: definition
annotated target: A hematopoietic stem cell that exists during embryogenesis.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:978-60327-246-6

keratocyte
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001777
subclass of: neural crest derived fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001777
definition: A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-22T01:57:40Z
has_exact_synonym: corneal fibroblast
has_exact_synonym: corneal keratocyte
in subset: cellxgene subset
in subset: eye upper slim
in subset: human reference atlas

Axiom
annotated source: keratocyte
annotated property: definition
annotated target: A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:9780702029585

respiratory tract epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004802
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004802
definition: An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-23T04:38:49Z
database_cross_reference: BTO:0004533
has_exact_synonym: airway epithelial cell
has_exact_synonym: respiratory epithelial cell
in subset: cellxgene subset

Axiom
annotated source: respiratory tract epithelial cell
annotated property: definition
annotated target: An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin.
database_cross_reference: GOC:tfm

myotube
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: has part
    some values from: GO_0030017
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001908
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002478
subclass of: striated muscle cell
subclass of: CL_4052002
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002478
definition: A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-09-24T01:13:01Z
has_exact_synonym: myofiber
has_exact_synonym: myofibril
in subset: cellxgene subset

Axiom
annotated source: myotube
annotated property: definition
annotated target: A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development.
database_cross_reference: GOC:dos
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0323052908
database_cross_reference: PMID:22274696

Axiom
annotated source: myotube
annotated property: has_exact_synonym
annotated target: myofiber
database_cross_reference: FBbt:00005812

Axiom
annotated source: myotube
annotated property: has_exact_synonym
annotated target: myofibril
database_cross_reference: FBbt:00005812

nucleated reticulocyte
type: Class
equivalent class: Class
  intersection of: reticulocyte
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002505
subclass of: reticulocyte
subclass of: nucleate cell
definition: A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-10-15T09:24:05Z

Axiom
annotated source: nucleated reticulocyte
annotated property: subClassOf
annotated target: reticulocyte
is inferred: true

Axiom
annotated source: nucleated reticulocyte
annotated property: definition
annotated target: A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:18182572
database_cross_reference: PMID:9011180
database_cross_reference: PMID:9046052

cardiocyte
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007100
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007100
definition: A cell located in the heart, including both muscle and non muscle cells.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-12-07T09:37:22Z
database_cross_reference: BTO:0001539
database_cross_reference: CALOHA:TS-0115
database_cross_reference: FMA:83808
database_cross_reference: FMA:84791
has_exact_synonym: heart cell
comment: From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart.

Axiom
annotated source: cardiocyte
annotated property: definition
annotated target: A cell located in the heart, including both muscle and non muscle cells.
database_cross_reference: GOC:tfm

adventitial cell
type: Class
equivalent class: Class
  intersection of: connective tissue cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0005742
subclass of: supporting cell
subclass of: connective tissue cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0005742
definition: A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2010-12-07T04:03:56Z
database_cross_reference: BTO:0002441
database_cross_reference: FMA:84639
in subset: cellxgene subset

Axiom
annotated source: adventitial cell
annotated property: definition
annotated target: A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc
database_cross_reference: GOC:tfm

enteric smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000160
subclass of: smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000160
definition: A smooth muscle cell of the intestine.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-01-17T03:39:38Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002504
has_exact_synonym: intestinal smooth muscle cell
in subset: cellxgene subset

Axiom
annotated source: enteric smooth muscle cell
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: enteric smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell of the intestine.
database_cross_reference: GOC:tfm

subcutaneous adipocyte
type: Class
equivalent class: Class
  intersection of: adipocyte
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002190
subclass of: adipocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002190
definition: An adipocyte that is part of subcutaneous adipose tissue.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-21T02:51:22Z
has_exact_synonym: subcutaneous fat cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: subcutaneous adipocyte
annotated property: subClassOf
annotated target: adipocyte
is inferred: true

Axiom
annotated source: subcutaneous adipocyte
annotated property: definition
annotated target: An adipocyte that is part of subcutaneous adipose tissue.
database_cross_reference: GOC:tfm

intrahepatic cholangiocyte
type: Class
equivalent class: Class
  intersection of: CL_1000488
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004823
subclass of: CL_1000488
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004823
definition: An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T01:20:20Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002538
has_exact_synonym: small bile duct cholangiocyte
in subset: cellxgene subset

Axiom
annotated source: intrahepatic cholangiocyte
annotated property: subClassOf
annotated target: CL_1000488
is inferred: true

Axiom
annotated source: intrahepatic cholangiocyte
annotated property: definition
annotated target: An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:23720296

Axiom
annotated source: intrahepatic cholangiocyte
annotated property: has_exact_synonym
annotated target: small bile duct cholangiocyte
database_cross_reference: PMID:23720296

aortic smooth muscle cell
type: Class
equivalent class: Class
  intersection of: vascular associated smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004178
subclass of: blood vessel smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004178
definition: A smooth muscle cell of the aorta.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T01:42:12Z
database_cross_reference: BTO:0004577
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002539
in subset: cellxgene subset

Axiom
annotated source: aortic smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell of the aorta.
database_cross_reference: GOC:tfm

mesenchymal stem cell of the bone marrow
type: Class
equivalent class: Class
  intersection of: mesenchymal stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002371
subclass of: mesenchymal stem cell
subclass of: bone marrow cell
definition: A mesenchymal stem cell that is part of the bone marrow.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T01:47:47Z

Axiom
annotated source: mesenchymal stem cell of the bone marrow
annotated property: definition
annotated target: A mesenchymal stem cell that is part of the bone marrow.
database_cross_reference: GOC:tfm

vein endothelial cell
type: Class
equivalent class: Class
  intersection of: blood vessel endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001638
subclass of: blood vessel endothelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001638
definition: An endothelial cell that is part of the vein.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T03:48:11Z
database_cross_reference: FMA:62104
database_cross_reference: KUPO:0001099
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002543
has_exact_synonym: endothelial cell of vein
has_exact_synonym: venous endothelial cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: vein endothelial cell
annotated property: subClassOf
annotated target: blood vessel endothelial cell
is inferred: true

Axiom
annotated source: vein endothelial cell
annotated property: definition
annotated target: An endothelial cell that is part of the vein.
database_cross_reference: GOC:tfm

fibroblast of the aortic adventitia
type: Class
equivalent class: Class
  intersection of: fibroblast of tunica adventitia of artery
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004664
subclass of: fibroblast of tunica adventitia of artery
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004664
definition: A fibroblast of the aortic adventitia.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T04:43:41Z

Axiom
annotated source: fibroblast of the aortic adventitia
annotated property: subClassOf
annotated target: fibroblast of tunica adventitia of artery
is inferred: true

Axiom
annotated source: fibroblast of the aortic adventitia
annotated property: definition
annotated target: A fibroblast of the aortic adventitia.
database_cross_reference: GOC:tfm

fibroblast of cardiac tissue
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000948
subclass of: fibroblast
subclass of: cardiocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000948
definition: A fibroblast that is part of the heart.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T04:57:44Z
has_exact_synonym: cardiac fibroblast
in subset: cellxgene subset

Axiom
annotated source: fibroblast of cardiac tissue
annotated property: subClassOf
annotated target: fibroblast
is inferred: true

Axiom
annotated source: fibroblast of cardiac tissue
annotated property: subClassOf
annotated target: cardiocyte
is inferred: true

Axiom
annotated source: fibroblast of cardiac tissue
annotated property: definition
annotated target: A fibroblast that is part of the heart.
database_cross_reference: GOC:tfm

fibroblast of dermis
type: Class
equivalent class: Class
  intersection of: skin fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002067
subclass of: skin fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002067
definition: Any skin fibroblast that is part of some dermis.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T05:05:33Z

Axiom
annotated source: fibroblast of dermis
annotated property: subClassOf
annotated target: skin fibroblast
is inferred: true

Axiom
annotated source: fibroblast of dermis
annotated property: definition
annotated target: Any skin fibroblast that is part of some dermis.
database_cross_reference: FBC:Autogenerated

fibroblast of lung
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002048
subclass of: fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002048
definition: A fibroblast that is part of lung.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T05:11:03Z
database_cross_reference: BTO:0000764
database_cross_reference: CALOHA:TS-0575
in subset: cellxgene subset

Axiom
annotated source: fibroblast of lung
annotated property: subClassOf
annotated target: fibroblast
is inferred: true

Axiom
annotated source: fibroblast of lung
annotated property: definition
annotated target: A fibroblast that is part of lung.
database_cross_reference: GOC:tfm

fibroblast of pulmonary artery
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002012
subclass of: fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002012
definition: A fibroblast of pulmonary artery.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-02-28T05:22:27Z
in subset: human reference atlas

Axiom
annotated source: fibroblast of pulmonary artery
annotated property: subClassOf
annotated target: fibroblast
is inferred: true

Axiom
annotated source: fibroblast of pulmonary artery
annotated property: definition
annotated target: A fibroblast of pulmonary artery.
database_cross_reference: GOC:tfm

intestinal epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001277
subclass of: epithelial cell of alimentary canal
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001277
definition: An epithelial cell of the lining of the intestine.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-01T05:18:31Z
in subset: cellxgene subset

Axiom
annotated source: intestinal epithelial cell
annotated property: definition
annotated target: An epithelial cell of the lining of the intestine.
database_cross_reference: GOC:tfm

mesenchymal stem cell of adipose tissue
type: Class
equivalent class: Class
  intersection of: mesenchymal stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001013
subclass of: mesenchymal stem cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001013
definition: A mesenchymal stem cell of adipose tissue.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-01T09:57:17Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002570
has_exact_synonym: mesenchymal stem cell of adipose
in subset: cellxgene subset

Axiom
annotated source: mesenchymal stem cell of adipose tissue
annotated property: definition
annotated target: A mesenchymal stem cell of adipose tissue.
database_cross_reference: GOC:tfm

hepatic mesenchymal stem cell
type: Class
equivalent class: Class
  intersection of: mesenchymal stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002107
subclass of: mesenchymal stem cell
subclass of: hepatic stem cell
definition: A mesenchymal stem cell of liver.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-01T09:58:51Z

Axiom
annotated source: hepatic mesenchymal stem cell
annotated property: subClassOf
annotated target: mesenchymal stem cell
is inferred: true

Axiom
annotated source: hepatic mesenchymal stem cell
annotated property: definition
annotated target: A mesenchymal stem cell of liver.
database_cross_reference: GOC:tfm

vertebral mesenchymal stem cell
type: Class
equivalent class: Class
  intersection of: mesenchymal stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002412
subclass of: mesenchymal stem cell
subclass of: bone cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002412
definition: A mesenchymal stem cell of the vertebrae.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-01T10:40:27Z

Axiom
annotated source: vertebral mesenchymal stem cell
annotated property: subClassOf
annotated target: mesenchymal stem cell
is inferred: true

Axiom
annotated source: vertebral mesenchymal stem cell
annotated property: definition
annotated target: A mesenchymal stem cell of the vertebrae.
database_cross_reference: GOC:tfm

stromal cell of pancreas
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: stromal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001264
definition: A stromal cell of the pancreas.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-02T02:40:41Z
in subset: human reference atlas

Axiom
annotated source: stromal cell of pancreas
annotated property: subClassOf
annotated target: stromal cell
is inferred: true

Axiom
annotated source: stromal cell of pancreas
annotated property: definition
annotated target: A stromal cell of the pancreas.
database_cross_reference: GOC:tfm

retinal blood vessel endothelial cell
type: Class
equivalent class: Class
  intersection of: blood vessel endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000966
subclass of: blood vessel endothelial cell
subclass of: retinal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000966
definition: A blood vessel endothelial cell that is part of the retina.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T03:28:27Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002585
in subset: cellxgene subset
in subset: eye upper slim
in subset: human reference atlas

Axiom
annotated source: retinal blood vessel endothelial cell
annotated property: subClassOf
annotated target: blood vessel endothelial cell
is inferred: true

Axiom
annotated source: retinal blood vessel endothelial cell
annotated property: definition
annotated target: A blood vessel endothelial cell that is part of the retina.
database_cross_reference: GOC:tfm

smooth muscle cell of the brachiocephalic vasculature
type: Class
equivalent class: Class
  intersection of: vascular associated smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001529
subclass of: blood vessel smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001529
definition: A smooth muscle cell of the bachiocephalic vasculature.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:00:58Z

Axiom
annotated source: smooth muscle cell of the brachiocephalic vasculature
annotated property: definition
annotated target: A smooth muscle cell of the bachiocephalic vasculature.
database_cross_reference: GOC:tfm

smooth muscle cell of the brain vasculature
type: Class
equivalent class: Class
  intersection of: vascular associated smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000955
subclass of: vascular associated smooth muscle cell
subclass of: neural cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000955
definition: A vascular associated smooth muscle cell of the brain vasculature.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:01:20Z

Axiom
annotated source: smooth muscle cell of the brain vasculature
annotated property: subClassOf
annotated target: vascular associated smooth muscle cell
is inferred: true

Axiom
annotated source: smooth muscle cell of the brain vasculature
annotated property: definition
annotated target: A vascular associated smooth muscle cell of the brain vasculature.
database_cross_reference: GOC:tfm

smooth muscle cell of the pulmonary artery
type: Class
equivalent class: Class
  intersection of: vascular associated smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002012
subclass of: blood vessel smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002012
definition: A smooth muscle of the pulmonary artery.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:01:28Z
database_cross_reference: BTO:0003336
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002591
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: smooth muscle cell of the pulmonary artery
annotated property: definition
annotated target: A smooth muscle of the pulmonary artery.
database_cross_reference: GOC:tfm

smooth muscle cell of the subclavian artery
type: Class
equivalent class: Class
  intersection of: vascular associated smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001533
subclass of: blood vessel smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001533
definition: A smooth muscle cell of the subclavian artery.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:01:52Z

Axiom
annotated source: smooth muscle cell of the subclavian artery
annotated property: definition
annotated target: A smooth muscle cell of the subclavian artery.
database_cross_reference: GOC:tfm

smooth muscle cell of the carotid artery
type: Class
equivalent class: Class
  intersection of: vascular associated smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0005396
subclass of: blood vessel smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0005396
definition: Smooth muscle cell of the carotid artery.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:01:56Z

Axiom
annotated source: smooth muscle cell of the carotid artery
annotated property: definition
annotated target: Smooth muscle cell of the carotid artery.
database_cross_reference: GOC:tfm

bronchial smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002185
subclass of: tracheobronchial smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002185
definition: Any smooth muscle cell that is part of some bronchus.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:46:39Z
database_cross_reference: BTO:0004402
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002598
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: bronchial smooth muscle cell
annotated property: definition
annotated target: Any smooth muscle cell that is part of some bronchus.
database_cross_reference: FBC:Autogenerated

smooth muscle cell of the esophagus
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001043
subclass of: smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001043
definition: A smooth muscle cell of the esophagus.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:48:17Z

Axiom
annotated source: smooth muscle cell of the esophagus
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: smooth muscle cell of the esophagus
annotated property: definition
annotated target: A smooth muscle cell of the esophagus.
database_cross_reference: GOC:tfm

smooth muscle cell of trachea
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0003126
subclass of: tracheobronchial smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0003126
definition: A smooth muscle cell of the trachea.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T05:50:28Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0002600
in subset: cellxgene subset

Axiom
annotated source: smooth muscle cell of trachea
annotated property: definition
annotated target: A smooth muscle cell of the trachea.
database_cross_reference: GOC:tfm

raphe nuclei neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0004684
subclass of: CL_2000029
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0004684
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: A neuron of the raphe nuclei.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T07:42:06Z

Axiom
annotated source: raphe nuclei neuron
annotated property: definition
annotated target: A neuron of the raphe nuclei.
database_cross_reference: GOC:tfm

neuron of the ventral spinal cord
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0002257
subclass of: CL_2000029
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0002257
definition: A neuron of the ventral spinal cord.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-06T07:46:03Z

Axiom
annotated source: neuron of the ventral spinal cord
annotated property: definition
annotated target: A neuron of the ventral spinal cord.
database_cross_reference: GOC:tfm

skin fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002097
subclass of: fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002097
definition: A fibroblast of skin.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-03-14T12:31:49Z
database_cross_reference: BTO:0001255
database_cross_reference: CALOHA:TS-0935
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: skin fibroblast
annotated property: subClassOf
annotated target: fibroblast
is inferred: true

Axiom
annotated source: skin fibroblast
annotated property: definition
annotated target: A fibroblast of skin.
database_cross_reference: GOC:tfm

epithelial cell of lower respiratory tract
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004815
subclass of: respiratory tract epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004815
definition: Any epithelial cell that is part of some lower respiratory tract epithelium.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-06-21T12:29:31Z
in subset: cellxgene subset

Axiom
annotated source: epithelial cell of lower respiratory tract
annotated property: definition
annotated target: Any epithelial cell that is part of some lower respiratory tract epithelium.
database_cross_reference: FBC:Autogenerated

squamous endothelial cell
type: Class
subclass of: endothelial cell
definition: A squamous shaped endothelial cell.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-07-08T03:31:25Z

Axiom
annotated source: squamous endothelial cell
annotated property: definition
annotated target: A squamous shaped endothelial cell.
database_cross_reference: GOC:dos

glandular cell of esophagus
type: Class
equivalent class: Class
  intersection of: glandular secretory epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001976
subclass of: glandular secretory epithelial cell
subclass of: epithelial cell of esophagus
definition: A glandular epithelial cell of the esophagus.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-07-08T03:55:57Z
database_cross_reference: FMA:86548
in subset: cellxgene subset

Axiom
annotated source: glandular cell of esophagus
annotated property: subClassOf
annotated target: glandular secretory epithelial cell
is inferred: true

Axiom
annotated source: glandular cell of esophagus
annotated property: subClassOf
annotated target: epithelial cell of esophagus
is inferred: true

Axiom
annotated source: glandular cell of esophagus
annotated property: definition
annotated target: A glandular epithelial cell of the esophagus.
database_cross_reference: GOC:tfm

glandular cell of the large intestine
type: Class
equivalent class: Class
  intersection of: glandular secretory epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000059
subclass of: glandular secretory epithelial cell
subclass of: epithelial cell of large intestine
definition: A glandular epithelial cell of the large intestine.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-07-08T04:03:01Z
database_cross_reference: FMA:87194

Axiom
annotated source: glandular cell of the large intestine
annotated property: subClassOf
annotated target: glandular secretory epithelial cell
is inferred: true

Axiom
annotated source: glandular cell of the large intestine
annotated property: definition
annotated target: A glandular epithelial cell of the large intestine.
database_cross_reference: GOC:tfm

glandular epithelial cell of stomach
type: Class
equivalent class: Class
  intersection of: glandular secretory epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001276
subclass of: glandular secretory epithelial cell
subclass of: epithelial cell of stomach
definition: A glandular epithelial cell that is part of the stomach.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-07-11T01:20:35Z
database_cross_reference: CALOHA:TS-1284
database_cross_reference: FMA:86554
has_exact_synonym: glandular cell of stomach

Axiom
annotated source: glandular epithelial cell of stomach
annotated property: definition
annotated target: A glandular epithelial cell that is part of the stomach.
database_cross_reference: GOC:tfm

myocardial endocrine cell of atrium
type: Class
equivalent class: Class
  intersection of: myocardial endocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002081
subclass of: myocardial endocrine cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002081
definition: A myocardial endocrine cell that is part of the atrium.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-07-11T02:45:39Z
database_cross_reference: FMA:83389

Axiom
annotated source: myocardial endocrine cell of atrium
annotated property: subClassOf
annotated target: myocardial endocrine cell
is inferred: true

Axiom
annotated source: myocardial endocrine cell of atrium
annotated property: definition
annotated target: A myocardial endocrine cell that is part of the atrium.
database_cross_reference: GOC:tfm

cardioblast
type: Class
subclass of: multi fate stem cell
definition: A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-07-11T03:15:38Z
has_exact_synonym: cardiovascular progenitor cell
has related synonym: CPC
comment: Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell.

Axiom
annotated source: cardioblast
annotated property: definition
annotated target: A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19745164

Axiom
annotated source: cardioblast
annotated property: has_exact_synonym
annotated target: cardiovascular progenitor cell
database_cross_reference: PMID:17519333
database_cross_reference: PMID:19745164

Axiom
annotated source: cardioblast
annotated property: hasRelatedSynonym
annotated target: CPC
database_cross_reference: PMID:19745164
has synonym type: OMO_0003000

retinal progenitor cell
type: Class
subclass of: multi fate stem cell
subclass of: Restriction
  on property: develops from
  some values from: neurectodermal cell
definition: A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-08-16T02:38:01Z
in subset: cellxgene subset

Axiom
annotated source: retinal progenitor cell
annotated property: definition
annotated target: A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:20959166
database_cross_reference: PMID:21148186

neural crest derived neuroblast
type: Class
subclass of: neuroblast (sensu Vertebrata)
subclass of: progenitor cell
subclass of: Restriction
  on property: develops from
  some values from: migratory neural crest cell
definition: A neuroblast derived from a neural crest cell.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-08-22T09:24:15Z

Axiom
annotated source: neural crest derived neuroblast
annotated property: definition
annotated target: A neuroblast derived from a neural crest cell.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:17407019

PP cell of intestine
type: Class
equivalent class: Class
  intersection of: PP cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001277
subclass of: PP cell
subclass of: CL_1001516
definition: A PP cell found in intestine.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2011-09-27T11:59:01Z

Axiom
annotated source: PP cell of intestine
annotated property: subClassOf
annotated target: PP cell
is inferred: true

Axiom
annotated source: PP cell of intestine
annotated property: definition
annotated target: A PP cell found in intestine.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:2420136
database_cross_reference: PMID:728970

spinal cord interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0002240
subclass of: interneuron
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0002240
definition: A CNS interneuron located in the spinal cord.
comment: Is_a interneuron, part_of UBERON:0002240.

Axiom
annotated source: spinal cord interneuron
annotated property: subClassOf
annotated target: interneuron
is inferred: true

Axiom
annotated source: spinal cord interneuron
annotated property: definition
annotated target: A CNS interneuron located in the spinal cord.
database_cross_reference: CL:CVS

somatomotor neuron
type: Class
equivalent class: Class
  intersection of: motor neuron
  intersection of: Restriction
    on property: synapsed to
    some values from: skeletal muscle fiber
subclass of: motor neuron
subclass of: cholinergic neuron
subclass of: Restriction
  on property: part of
  some values from: RO_0002577
subclass of: Restriction
  on property: synapsed to
  some values from: skeletal muscle fiber
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic.
has_exact_synonym: somatic motor neuron

Axiom
annotated source: somatomotor neuron
annotated property: definition
annotated target: A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic.
database_cross_reference: ZFIN:CVS

hepatoblast
type: Class
subclass of: multi fate stem cell
definition: Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation.
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0005026
in subset: cellxgene subset

Axiom
annotated source: hepatoblast
annotated property: definition
annotated target: Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation.
database_cross_reference: GOC:CVS
database_cross_reference: PMID:18356246
database_cross_reference: PMID:20483998
database_cross_reference: PMID:26798363
database_cross_reference: https://orcid.org/0000-0003-1940-6740

skeletogenic cell
type: Class
subclass of: cell
definition: Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized).
contributor: https://orcid.org/0000-0001-9114-8737
creation date: 2012-06-15T02:51:27Z
has_exact_synonym: scleroblast
comment: Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts)

Axiom
annotated source: skeletogenic cell
annotated property: definition
annotated target: Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized).
database_cross_reference: GO_REF:0000034

Axiom
annotated source: skeletogenic cell
annotated property: has_exact_synonym
annotated target: scleroblast
database_cross_reference: GO_REF:0000034

premigratory neural crest cell
type: Class
subclass of: neural crest cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002342
subclass of: Restriction
  on property: develops from
  some values from: neurectodermal cell
definition: Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells.
contributor: https://orcid.org/0000-0001-9114-8737
creation date: 2012-06-27T08:27:35Z

Axiom
annotated source: premigratory neural crest cell
annotated property: definition
annotated target: Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells.
database_cross_reference: UBERONREF:0000002

prechondroblast
type: Class
subclass of: non-terminally differentiated cell
definition: Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells.
contributor: https://orcid.org/0000-0001-9114-8737
creation date: 2012-06-27T10:44:01Z

Axiom
annotated source: prechondroblast
annotated property: definition
annotated target: Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells.
database_cross_reference: GO_REF:0000034

non-striated muscle cell
type: Class
subclass of: muscle cell
definition: Any muscle cell in which the fibers are not organised into sarcomeres.

Axiom
annotated source: non-striated muscle cell
annotated property: definition
annotated target: Any muscle cell in which the fibers are not organised into sarcomeres.
database_cross_reference: GOC:DOS

hematopoietic precursor cell
type: Class
subclass of: hematopoietic cell
definition: Any hematopoietic cell that is a precursor of some other hematopoietic cell type.
in subset: cellxgene subset

Axiom
annotated source: hematopoietic precursor cell
annotated property: definition
annotated target: Any hematopoietic cell that is a precursor of some other hematopoietic cell type.
database_cross_reference: GOC:dos

skeletal muscle fiber
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001134
  intersection of: Restriction
    on property: has part
    some values from: GO_0030017
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001908
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002478
subclass of: cell of skeletal muscle
subclass of: myotube
subclass of: Restriction
  on property: develops from
  some values from: skeletal muscle myoblast
definition: A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
database_cross_reference: MESH:D018485
in subset: cellxgene subset

Axiom
annotated source: skeletal muscle fiber
annotated property: definition
annotated target: A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0323052908

visceral muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_8600004
subclass of: muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_8600004
definition: A muscle cell that is part of some visceral muscle.

Axiom
annotated source: visceral muscle cell
annotated property: definition
annotated target: A muscle cell that is part of some visceral muscle.
database_cross_reference: GOC:dos

striated visceral muscle cell
type: Class
equivalent class: Class
  intersection of: visceral muscle cell
  intersection of: Class
    intersection of: Restriction
      on property: has part
      some values from: GO_0030017
    intersection of: Restriction
      on property: has characteristic
      some values from: PATO_0001410
subclass of: striated muscle cell
subclass of: visceral muscle cell
definition: A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods.

Axiom
annotated source: striated visceral muscle cell
annotated property: definition
annotated target: A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods.
database_cross_reference: GOC:dos

transversely striated visceral muscle cell
type: Class
equivalent class: Class
  intersection of: visceral muscle cell
  intersection of: Class
    intersection of: Restriction
      on property: has part
      some values from: GO_0030017
    intersection of: Restriction
      on property: has characteristic
      some values from: PATO_0002478
subclass of: striated visceral muscle cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002478
definition: A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods.

Axiom
annotated source: transversely striated visceral muscle cell
annotated property: definition
annotated target: A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods.
database_cross_reference: GOC:dos

adult skeletal muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001134
  intersection of: Restriction
    on property: develops into
    some values from: skeletal muscle fiber
subclass of: cell of skeletal muscle
subclass of: skeletal muscle myoblast
definition: A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers.
has broad synonym: myogenic precursor cell
comment: The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins.

Axiom
annotated source: adult skeletal muscle myoblast
annotated property: definition
annotated target: A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers.
database_cross_reference: PMID:23303905

Axiom
annotated source: adult skeletal muscle myoblast
annotated property: hasBroadSynonym
annotated target: myogenic precursor cell
database_cross_reference: PMID:23303905

mesenchymal cell
type: Class
subclass of: motile cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0003104
subclass of: Restriction
  on property: capable of
  some values from: GO_0016477
definition: A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration.
RO_0002175: NCBITaxon 9606
has_exact_synonym: mesenchyme cell
in subset: cellxgene subset
in subset: human reference atlas

endocardial cushion cell
type: Class
equivalent class: Class
  intersection of: cardiac mesenchymal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002062
subclass of: cardiac mesenchymal cell
subclass of: cardiocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002062
definition: A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves.

Axiom
annotated source: endocardial cushion cell
annotated property: definition
annotated target: A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves.
database_cross_reference: PMID:18816864

pancreatic endocrine cell
type: Class
equivalent class: Class
  intersection of: endocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: epithelial cell of pancreas
subclass of: enteroendocrine cell
definition: An endocrine cell that is part of the pancreas.
RO_0002175: NCBITaxon 9606
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: pancreatic endocrine cell
annotated property: definition
annotated target: An endocrine cell that is part of the pancreas.
database_cross_reference: GOC:dos

noradrenergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0061533
subclass of: noradrenergic cell
subclass of: CL_4033050
subclass of: Restriction
  on property: capable of
  some values from: GO_0061533
definition: A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter.

Axiom
annotated source: noradrenergic neuron
annotated property: definition
annotated target: A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter.
database_cross_reference: GOC:dos

visual system neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of part of
    some values from: GO_0007601
subclass of: neuron
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0007601
definition: Any neuron that is capable of part of some visual perception.
contributor: https://orcid.org/0000-0002-7073-9172
creation date: 2017-07-09T19:12:36Z

Axiom
annotated source: visual system neuron
annotated property: definition
annotated target: Any neuron that is capable of part of some visual perception.
database_cross_reference: FBC:Autogenerated

mural cell
type: Class
subclass of: CL_4033054
definition: Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0002-7073-9172
creation date: 2020-02-29T17:33:55Z
in subset: added for HCA
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: mural cell
annotated property: definition
annotated target: Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation.
database_cross_reference: Wiki:Mural_cell&oldid=930603194

microcirculation associated smooth muscle cell
type: Class
equivalent class: Class
  intersection of: vascular associated smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0010523
subclass of: vascular associated smooth muscle cell
subclass of: mural cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0010523
definition: Any vascular associated smooth muscle cell that is part of some microcirculatory vessel.
contributor: https://orcid.org/0000-0002-7073-9172
creation date: 2020-02-29T17:37:00Z

Axiom
annotated source: microcirculation associated smooth muscle cell
annotated property: definition
annotated target: Any vascular associated smooth muscle cell that is part of some microcirculatory vessel.
database_cross_reference: FBC:Autogenerated

mesothelial cell of intestine
type: Class
equivalent class: Class
  intersection of: mesothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001243
subclass of: mesothelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001243
definition: A mesothelial cell that is part of the intestinal serosa.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2025-02-04T18:42:26Z

Axiom
annotated source: mesothelial cell of intestine
annotated property: definition
annotated target: A mesothelial cell that is part of the intestinal serosa.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

sensory neuron of spinal nerve
type: Class
equivalent class: Class
  intersection of: sensory neuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0001780
subclass of: CL_3000004
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0001780
definition: A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord.
has_exact_synonym: spinal sensory neuron

Axiom
annotated source: sensory neuron of spinal nerve
annotated property: definition
annotated target: A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord.
database_cross_reference: GOC:nv
database_cross_reference: GOC:pr

compound eye retinal cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: Class
      intersection of: UBERON_0005388
      intersection of: Restriction
        on property: part of
        some values from: UBERON_0000018
subclass of: retinal cell
subclass of: Restriction
  on property: part of
  some values from: Class
    intersection of: UBERON_0005388
    intersection of: Restriction
      on property: part of
      some values from: UBERON_0000018
definition: Any cell in the compound eye, a light sensing organ composed of ommatidia.
database_cross_reference: GOC:pr
database_cross_reference: PMID:12021768

retinal cell
type: Class
equivalent class: Class
  intersection of: neural cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0005388
subclass of: neural cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0005388
definition: Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
database_cross_reference: PMID:10702418
in subset: general cell types upper slim

Axiom
annotated source: retinal cell
annotated property: definition
annotated target: Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
database_cross_reference: GOC:pr

enteroendocrine cell of small intestine
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002108
subclass of: CL_1001516
subclass of: CL_1001598
definition: An enteroendocrine cell that is located in the small intestine.
contributor: https://orcid.org/0000-0002-2825-0621
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0009006
has_exact_synonym: small intestine enteroendocrine cell
in subset: cellxgene subset
in subset: location grouping

Axiom
annotated source: enteroendocrine cell of small intestine
annotated property: definition
annotated target: An enteroendocrine cell that is located in the small intestine.
database_cross_reference: http://orcid.org/0000-0003-3440-1876

intestinal crypt stem cell of large intestine
type: Class
equivalent class: Class
  intersection of: intestinal crypt stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001984
subclass of: intestinal crypt stem cell
subclass of: epithelial cell of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001984
definition: An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0002-2825-0621
has broad synonym: crypt stem cell of large intestine
has_exact_synonym: stem cell of large intestine crypt of Lieberkuhn
in subset: cellxgene subset
in subset: location grouping
in subset: human reference atlas

Axiom
annotated source: intestinal crypt stem cell of large intestine
annotated property: definition
annotated target: An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.
database_cross_reference: PMID:20683682
database_cross_reference: https://orcid.org/0000-0003-4183-8865

intestinal crypt stem cell of small intestine
type: Class
equivalent class: Class
  intersection of: intestinal crypt stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001241
subclass of: intestinal crypt stem cell
subclass of: epithelial cell of small intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001241
definition: An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.
contributor: https://orcid.org/0000-0002-2825-0621
has broad synonym: crypt stem cell of small intestine
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0009017
has_exact_synonym: stem cell of small intestine crypt of Lieberkuhn
in subset: cellxgene subset
in subset: location grouping

Axiom
annotated source: intestinal crypt stem cell of small intestine
annotated property: definition
annotated target: An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.
database_cross_reference: PMID:20683682
database_cross_reference: https://orcid.org/0000-0003-4183-8865

stromal cell of lamina propria of large intestine
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0011189
subclass of: stromal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0011189
definition: A stromal cell found in the lamina propria of the large intestine.
contributor: https://orcid.org/0000-0002-2825-0621
in subset: location grouping

Axiom
annotated source: stromal cell of lamina propria of large intestine
annotated property: definition
annotated target: A stromal cell found in the lamina propria of the large intestine.
database_cross_reference: http://orcid.org/0000-0003-4183-8865

stromal cell of lamina propria of small intestine
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001238
subclass of: stromal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001238
definition: A stromal cell found in the lamina propria of the small intestine.
contributor: https://orcid.org/0000-0002-2825-0621
in subset: cellxgene subset
in subset: location grouping

Axiom
annotated source: stromal cell of lamina propria of small intestine
annotated property: definition
annotated target: A stromal cell found in the lamina propria of the small intestine.
database_cross_reference: http://orcid.org/0000-0003-4183-8865

mesothelial cell of small intestine
type: Class
equivalent class: Class
  intersection of: mesothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001206
subclass of: mesothelial cell of intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001206
definition: A mesothelial cell that is part of the small intestine.
contributor: https://orcid.org/0000-0002-2825-0621
in subset: location grouping

Axiom
annotated source: mesothelial cell of small intestine
annotated property: definition
annotated target: A mesothelial cell that is part of the small intestine.
database_cross_reference: http://orcid.org/0000-0003-4183-8865

mesothelial cell of colon
type: Class
equivalent class: Class
  intersection of: mesothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0003335
subclass of: mesothelial cell of intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0003335
definition: A mesothelial cell that is part of the colon.
contributor: https://orcid.org/0000-0002-2825-0621
has broad synonym: mesothelial cell of large intestine
in subset: location grouping

Axiom
annotated source: mesothelial cell of colon
annotated property: definition
annotated target: A mesothelial cell that is part of the colon.
database_cross_reference: http://orcid.org/0000-0003-3440-1876
database_cross_reference: http://orcid.org/0000-0003-4183-8865

stromal cell of lamina propria of colon
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007177
subclass of: stromal cell of lamina propria of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007177
definition: A stromal cell found in the lamina propria of the colon.
contributor: https://orcid.org/0000-0002-2825-0621
has_exact_synonym: stromal cell of colon lamina propria
in subset: location grouping

Axiom
annotated source: stromal cell of lamina propria of colon
annotated property: definition
annotated target: A stromal cell found in the lamina propria of the colon.
database_cross_reference: http://orcid.org/0000-0003-3440-1876

enteroendocrine cell of colon
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001155
subclass of: colon epithelial cell
subclass of: CL_1001516
definition: An enteroendocrine cell that is located in the colon.
contributor: https://orcid.org/0000-0002-2825-0621
has_exact_synonym: colon enteroendocrine cell
in subset: cellxgene subset
in subset: location grouping

Axiom
annotated source: enteroendocrine cell of colon
annotated property: definition
annotated target: An enteroendocrine cell that is located in the colon.
database_cross_reference: http://orcid.org/0000-0003-3440-1876

intestinal crypt stem cell of colon
type: Class
equivalent class: Class
  intersection of: intestinal crypt stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0013485
subclass of: intestinal crypt stem cell of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0013485
definition: An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon.
contributor: https://orcid.org/0000-0002-2825-0621
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0009043
in subset: cellxgene subset
in subset: location grouping

Axiom
annotated source: intestinal crypt stem cell of colon
annotated property: definition
annotated target: An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon.
database_cross_reference: PMID:10841502
database_cross_reference: http://orcid.org/0000-0003-3440-1876

smooth muscle cell of anorectum
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_8410050
subclass of: smooth muscle cell of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_8410050
definition: A smooth muscle cell that is located in the anorectum.
contributor: https://orcid.org/0000-0002-2825-0621
has_exact_synonym: anorectum smooth muscle cell
in subset: location grouping

Axiom
annotated source: smooth muscle cell of anorectum
annotated property: definition
annotated target: A smooth muscle cell that is located in the anorectum.
database_cross_reference: http://orcid.org/0000-0003-3440-1876

stromal cell of anorectum lamina propria
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0011189
  intersection of: Restriction
    on property: part of
    some values from: UBERON_8410050
subclass of: stromal cell of lamina propria of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_8410050
definition: A stromal cell found in the lamina propria of the anorectum.
contributor: https://orcid.org/0000-0002-2825-0621
in subset: location grouping

Axiom
annotated source: stromal cell of anorectum lamina propria
annotated property: definition
annotated target: A stromal cell found in the lamina propria of the anorectum.
database_cross_reference: http://orcid.org/0000-0003-3440-1876

intestinal crypt stem cell of anorectum
type: Class
equivalent class: Class
  intersection of: intestinal crypt stem cell of large intestine
  intersection of: Restriction
    on property: part of
    some values from: UBERON_8410050
subclass of: intestinal crypt stem cell of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_8410050
definition: An intestinal crypt stem cell that is located in the anorectum.
contributor: https://orcid.org/0000-0002-2825-0621
has_exact_synonym: anorectum intestinal crypt stem cell
in subset: location grouping

Axiom
annotated source: intestinal crypt stem cell of anorectum
annotated property: definition
annotated target: An intestinal crypt stem cell that is located in the anorectum.
database_cross_reference: http://orcid.org/0000-0003-3440-1876

enteroendocrine cell of anorectum
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_8410050
subclass of: epithelial cell of large intestine
subclass of: CL_1001516
subclass of: Restriction
  on property: part of
  some values from: UBERON_8410050
definition: An enteroendocrine cell that is located in the anorectum.
contributor: https://orcid.org/0000-0002-2825-0621
has_exact_synonym: anorectum enteroendocrine cell
in subset: location grouping

Axiom
annotated source: enteroendocrine cell of anorectum
annotated property: definition
annotated target: An enteroendocrine cell that is located in the anorectum.
database_cross_reference: http://orcid.org/0000-0003-3440-1876

endothelial cell of hepatic portal vein
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001639
subclass of: vein endothelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001639
definition: An endothelial cell that is part of a hepatic portal vein.
contributor: https://orcid.org/0000-0002-2825-0621
date: 2021-12-13T14:01:05Z
has broad synonym: portal endothelial cell
database_cross_reference: EFO:0010704
in subset: location grouping

Axiom
annotated source: endothelial cell of hepatic portal vein
annotated property: definition
annotated target: An endothelial cell that is part of a hepatic portal vein.
database_cross_reference: PMID:30348985
database_cross_reference: https://orcid.org/0000-0003-3440-1876
database_cross_reference: https://orcid.org/0000-0003-4183-8865

embryonic skeletal muscle fiber
type: Class
equivalent class: Class
  intersection of: skeletal muscle fiber
  intersection of: Restriction
    on property: existence starts and ends during
    some values from: UBERON_0000068
subclass of: skeletal muscle fiber
subclass of: Restriction
  on property: existence starts and ends during
  some values from: UBERON_0000068
definition: A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development.
contributor: https://orcid.org/0000-0002-2825-0621
date: 2022-02-21T15:39:10Z

Axiom
annotated source: embryonic skeletal muscle fiber
annotated property: definition
annotated target: A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development.
database_cross_reference: PMID:32094117
database_cross_reference: PMID:7196501
database_cross_reference: http://orcid.org/0000-0003-2034-601X

hepatic portal fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001279
subclass of: fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001279
definition: A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen.
RO_0002175: NCBITaxon 9606
contributor: https://orcid.org/0000-0002-2825-0621
date: 2022-03-17T12:00:44Z
has broad synonym: portal fibroblast
in subset: human reference atlas

Axiom
annotated source: hepatic portal fibroblast
annotated property: definition
annotated target: A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen.
database_cross_reference: PMID:20209607
database_cross_reference: PMID:24814904
database_cross_reference: https://orcid.org/0000-0001-7655-4833

stromal cell of bone marrow
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002371
subclass of: stromal cell
subclass of: bone marrow cell
definition: A stromal cell that is part_of a bone marrow.
contributor: https://orcid.org/0000-0002-6601-2165
has_exact_synonym: bone marrow stromal cell

cardiac blood vessel endothelial cell
type: Class
equivalent class: Class
  intersection of: blood vessel endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000948
subclass of: blood vessel endothelial cell
subclass of: cardiac endothelial cell
definition: Any blood vessel endothelial cell that is part of some heart.

Axiom
annotated source: cardiac blood vessel endothelial cell
annotated property: definition
annotated target: Any blood vessel endothelial cell that is part of some heart.
database_cross_reference: FBC:Autogenerated

His-Purkinje system cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004146
subclass of: cardiocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004146
definition: Any cell that is part of some His-Purkinje system.

Axiom
annotated source: His-Purkinje system cell
annotated property: definition
annotated target: Any cell that is part of some His-Purkinje system.
database_cross_reference: FBC:Autogenerated

cardiac endothelial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000948
subclass of: endothelial cell
subclass of: cardiocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000948
definition: Any endothelial cell that is part of some heart.
RO_0002175: NCBITaxon 9606
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0010008
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: cardiac endothelial cell
annotated property: definition
annotated target: Any endothelial cell that is part of some heart.
database_cross_reference: FBC:Autogenerated

camera-type eye photoreceptor cell
type: Class
equivalent class: Class
  intersection of: photoreceptor cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000019
subclass of: eye photoreceptor cell
subclass of: retinal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000966
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: Any photoreceptor cell that is part of some camera-type eye.
has_exact_synonym: camera type eye photoreceptor cell

Axiom
annotated source: camera-type eye photoreceptor cell
annotated property: definition
annotated target: Any photoreceptor cell that is part of some camera-type eye.
database_cross_reference: FBC:Autogenerated

zygote
type: Class
subclass of: cell
definition: A zygote in a plant or an animal.
database_cross_reference: MESH:D015053

cardiac glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000948
subclass of: glial cell
subclass of: cardiocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000948
definition: Any glial cell that is part of some heart.

Axiom
annotated source: cardiac glial cell
annotated property: definition
annotated target: Any glial cell that is part of some heart.
database_cross_reference: FBC:Autogenerated

cardiac myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: develops into
    some values from: cardiac muscle cell
subclass of: myoblast
subclass of: Restriction
  on property: develops into
  some values from: cardiac muscle cell
definition: Any myoblast that develops into some cardiac muscle cell.
database_cross_reference: MESH:D032386

Axiom
annotated source: cardiac myoblast
annotated property: definition
annotated target: Any myoblast that develops into some cardiac muscle cell.
database_cross_reference: FBC:Autogenerated

cardiac neuron
type: Class
equivalent class: Class
  intersection of: CL_2000032
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0000948
subclass of: CL_2000032
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0000948
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: A neuron that has its soma in the heart.
in subset: cellxgene subset
comment: This term is used in 3 GO terms that were created as part of the heart development focus project.

Axiom
annotated source: cardiac neuron
annotated property: definition
annotated target: A neuron that has its soma in the heart.
database_cross_reference: PMID:12486170
database_cross_reference: PMID:29265764

spinal cord motor neuron
type: Class
equivalent class: Class
  intersection of: motor neuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0002240
subclass of: motor neuron
subclass of: CL_2000029
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0002240
definition: A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.
in subset: cellxgene subset

Axiom
annotated source: spinal cord motor neuron
annotated property: subClassOf
annotated target: motor neuron
is inferred: true

Axiom
annotated source: spinal cord motor neuron
annotated property: definition
annotated target: A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.
database_cross_reference: GOC:nv

paraxial cell
type: Class
equivalent class: Class
  intersection of: mesodermal cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0003059
subclass of: mesodermal cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0003059
definition: A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites.
has_exact_synonym: paraxial mesoderm cell
has_exact_synonym: somitic mesoderm cell
has narrow synonym: presomitic mesoderm cell

Axiom
annotated source: paraxial cell
annotated property: definition
annotated target: A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites.
database_cross_reference: GOC:NV
database_cross_reference: PMID:11687492

neural crest cell
type: Class
subclass of: multi fate stem cell
subclass of: embryonic cell (metazoa)
definition: A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0011012
in subset: cellxgene subset

Axiom
annotated source: neural crest cell
annotated property: definition
annotated target: A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.
database_cross_reference: https://orcid.org/0000-0001-5208-3432
database_cross_reference: https://orcid.org/0000-0002-9900-7880

mesothelial cell of epicardium
type: Class
equivalent class: Class
  intersection of: mesothelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002348
subclass of: mesothelial cell
subclass of: cardiocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002348
definition: A mesothelial cell that is part of the epicardium.
contributor: https://orcid.org/0000-0001-5208-3432
in subset: cellxgene subset

fibroblast of upper back skin
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0009015
subclass of: fibroblast of skin of back
subclass of: Restriction
  on property: part of
  some values from: UBERON_0009015
definition: A fibroblast that is part of upper back skin.
contributor: https://orcid.org/0000-0001-5208-3432

fibroblast of skin of back
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001068
subclass of: skin fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001068
definition: A fibroblast that is part of skin of back.
contributor: https://orcid.org/0000-0001-5208-3432

progenitor cell
type: Class
equivalent class: Class
  intersection of: precursor cell
  intersection of: Restriction
    on property: develops from
    some values from: stem cell
subclass of: eukaryotic cell
subclass of: precursor cell
subclass of: Restriction
  on property: develops from
  some values from: stem cell
definition: A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.
contributor: https://orcid.org/0000-0001-5208-3432
in subset: cellxgene subset

Axiom
annotated source: progenitor cell
annotated property: definition
annotated target: A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.
database_cross_reference: ISBN:978-1-62808-994-3
database_cross_reference: https://doi.org/10.1016/B978-0-12-409503-8.00002-0

skeletal muscle fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001134
subclass of: cell of skeletal muscle
subclass of: CL_1001609
definition: Any fibroblast that is part of skeletal muscle tissue.
contributor: https://orcid.org/0000-0001-5208-3432
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0011027
has_exact_synonym: skeleton muscle fibroblast
in subset: cellxgene subset

Axiom
annotated source: skeletal muscle fibroblast
annotated property: definition
annotated target: Any fibroblast that is part of skeletal muscle tissue.
database_cross_reference: PMID:28369879
database_cross_reference: https://orcid.org/0000-0001-6164-0667

dermal microvascular endothelial cell
type: Class
equivalent class: Class
  intersection of: CL_2000008
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002067
subclass of: CL_2000008
subclass of: CL_2000010
definition: Any microvascular endothelial cell that is part of the dermis.
contributor: https://orcid.org/0000-0001-5208-3432
has_exact_synonym: DMEC cell
has_exact_synonym: dermal microvascular endothelium cell

Axiom
annotated source: dermal microvascular endothelial cell
annotated property: definition
annotated target: Any microvascular endothelial cell that is part of the dermis.
database_cross_reference: BTO:0004574
database_cross_reference: CL:patterns/cellPartOfAnatomicalEntity

colon epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000397
subclass of: epithelial cell of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000397
definition: Epithelial cell that is part of the colon epithelium.
has_exact_synonym: colonic epithelial cell
in subset: cellxgene subset

Axiom
annotated source: colon epithelial cell
annotated property: definition
annotated target: Epithelial cell that is part of the colon epithelium.
database_cross_reference: GOC:NV

precursor cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030154
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0030154
definition: A cell that, by division or terminal differentiation, can give rise to other cell types.
in subset: cellxgene subset
comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.

Axiom
annotated source: precursor cell
annotated property: definition
annotated target: A cell that, by division or terminal differentiation, can give rise to other cell types.
database_cross_reference: GOC:dos

acidophilic cytoplasm
type: Class
equivalent class: Class
  intersection of: GO_0005737
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002418
subclass of: GO_0005737
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002418
definition: Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2009-12-22T04:23:25Z
has narrow synonym: eosinophilic

Axiom
annotated source: acidophilic cytoplasm
annotated property: definition
annotated target: Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain.
database_cross_reference: GOC:add

basophilic cytoplasm
type: Class
equivalent class: Class
  intersection of: GO_0005737
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002094
subclass of: GO_0005737
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002094
definition: Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2009-12-22T04:24:54Z

Axiom
annotated source: basophilic cytoplasm
annotated property: definition
annotated target: Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions.
database_cross_reference: GOC:tfm

polychromatophilic cytoplasm
type: Class
equivalent class: Class
  intersection of: GO_0005737
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0070047
subclass of: GO_0005737
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0070047
definition: Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions.
contributor: https://orcid.org/0000-0003-1980-3228
creation date: 2009-12-28T04:25:23Z

Axiom
annotated source: polychromatophilic cytoplasm
annotated property: definition
annotated target: Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions.
database_cross_reference: GOC:tfm

tracheobronchial serous cell
type: Class
equivalent class: Class
  intersection of: serous secreting cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007196
subclass of: eukaryotic cell
subclass of: serous secreting cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007196
definition: Any serous secreting cell that is part of the tracheobronchial epithelium.
contributor: 0000-0003-2034-601X
date: 2020-05-07T16:03:27Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0019001
has_exact_synonym: serous cell of tracheobronchial tree
in subset: added for HCA
in subset: cellxgene subset

tracheobronchial chondrocyte
type: Class
equivalent class: Class
  intersection of: chondrocyte
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007196
subclass of: chondrocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007196
definition: Any chondrocyte that is part of the tracheobronchial tree.
RO_0002175: NCBITaxon 9606
contributor: 0000-0003-2034-601X
date: 2020-05-07T17:29:51Z
has_exact_synonym: chondrocyte of tracheobronchial tree
in subset: added for HCA
in subset: human reference atlas

blood vessel smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001981
subclass of: vascular associated smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001981
definition: A smooth muscle cell that is part of any blood vessel.
RO_0002175: NCBITaxon 9606
contributor: 0000-0003-2034-601X
date: 2020-07-21T12:42:48Z
has_exact_synonym: smooth muscle cell of blood vessel
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: blood vessel smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell that is part of any blood vessel.
database_cross_reference: PMID:9108778

tracheobronchial smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007196
subclass of: smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007196
subclass of: Restriction
  on property: has characterizing marker set
  some values from: CLM_1000056
definition: A smooth muscle cell that is part of the tracheobronchial tree.
RO_0002175: NCBITaxon 9606
contributor: 0000-0003-2034-601X
date: 2020-07-21T12:50:22Z
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_0019019
has_exact_synonym: smooth muscle cell of tracheobronchial tree
in subset: cellxgene subset
in subset: human reference atlas
comment: The marker set ACTA2, TAGLN can identify the Human cell type tracheobronchial smooth muscle cell in the Lung with a confidence of 0.69 (NS-Forest FBeta value).

Axiom
annotated source: tracheobronchial smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell that is part of the tracheobronchial tree.
database_cross_reference: PMID:10853867

Axiom
annotated source: tracheobronchial smooth muscle cell
annotated property: comment
annotated target: The marker set ACTA2, TAGLN can identify the Human cell type tracheobronchial smooth muscle cell in the Lung with a confidence of 0.69 (NS-Forest FBeta value).
database_cross_reference: https://doi.org/10.5281/zenodo.11165918

extrahepatic cholangiocyte
type: Class
equivalent class: Class
  intersection of: CL_1000488
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004822
subclass of: CL_1000488
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004822
definition: An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes.
contributor: 0000-0003-2034-601X
date: 2020-09-03T12:24:24Z
has_exact_synonym: large bile duct cholangiocyte

Axiom
annotated source: extrahepatic cholangiocyte
annotated property: definition
annotated target: An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes.
database_cross_reference: PMID:23720296

Axiom
annotated source: extrahepatic cholangiocyte
annotated property: has_exact_synonym
annotated target: large bile duct cholangiocyte
database_cross_reference: PMID:23720296

endothelial cell of periportal hepatic sinusoid
type: Class
equivalent class: Class
  intersection of: CL_1000398
  intersection of: Restriction
    on property: adjacent to
    some values from: UBERON_0001279
subclass of: CL_1000398
subclass of: Restriction
  on property: adjacent to
  some values from: UBERON_0001279
definition: An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid.
contributor: 0000-0003-2034-601X
date: 2020-09-09T13:56:47Z
database_cross_reference: EFO:0010705
has_exact_synonym: periportal LSEC
has_exact_synonym: periportal hepatic sinusoidal endothelial cell
in subset: cellxgene subset

Axiom
annotated source: endothelial cell of periportal hepatic sinusoid
annotated property: definition
annotated target: An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid.
database_cross_reference: PMID:27423426

Axiom
annotated source: endothelial cell of periportal hepatic sinusoid
annotated property: has_exact_synonym
annotated target: periportal LSEC
database_cross_reference: PMID:28287163

Axiom
annotated source: endothelial cell of periportal hepatic sinusoid
annotated property: has_exact_synonym
annotated target: periportal hepatic sinusoidal endothelial cell
database_cross_reference: PMID:30348985

endothelial cell of pericentral hepatic sinusoid
type: Class
equivalent class: Class
  intersection of: CL_1000398
  intersection of: Restriction
    on property: adjacent to
    some values from: UBERON_0006841
subclass of: CL_1000398
subclass of: Restriction
  on property: adjacent to
  some values from: UBERON_0006841
definition: An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid.
contributor: 0000-0003-2034-601X
date: 2020-09-10T12:38:29Z
database_cross_reference: EFO:0010706
has_exact_synonym: central venous hepatic sinusoidal endothelial cell
has_exact_synonym: pericentral LSEC
in subset: cellxgene subset

Axiom
annotated source: endothelial cell of pericentral hepatic sinusoid
annotated property: definition
annotated target: An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid.
database_cross_reference: PMID:27423426

Axiom
annotated source: endothelial cell of pericentral hepatic sinusoid
annotated property: has_exact_synonym
annotated target: central venous hepatic sinusoidal endothelial cell
database_cross_reference: PMID:30348985

Axiom
annotated source: endothelial cell of pericentral hepatic sinusoid
annotated property: has_exact_synonym
annotated target: pericentral LSEC
database_cross_reference: PMID:28287163

stomach neuroendocrine cell
type: Class
equivalent class: Class
  intersection of: neuroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001276
subclass of: neuroendocrine cell
subclass of: CL_1001517
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
subclass of: Restriction
  on property: capable of
  some values from: GO_0046717
definition: A specialised neuroendocrine cell located in the gastric mucosa that regulates digestive processes including acid secretion and gut motility. This cell stores hormones in large dense core vesicles and synaptic-like microvesicles.
has broad synonym: DES cell
has broad synonym: diffuse endocrine system cell

Axiom
annotated source: stomach neuroendocrine cell
annotated property: definition
annotated target: A specialised neuroendocrine cell located in the gastric mucosa that regulates digestive processes including acid secretion and gut motility. This cell stores hormones in large dense core vesicles and synaptic-like microvesicles.
database_cross_reference: PMID:15153415

Axiom
annotated source: stomach neuroendocrine cell
annotated property: hasBroadSynonym
annotated target: DES cell
database_cross_reference: PMID:15153415

Axiom
annotated source: stomach neuroendocrine cell
annotated property: hasBroadSynonym
annotated target: diffuse endocrine system cell
database_cross_reference: PMID:15153415

pulmonary neuroendocrine cell
type: Class
equivalent class: Class
  intersection of: neuroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002048
subclass of: neuronal receptor cell
subclass of: sensory epithelial cell
subclass of: neuroendocrine cell
subclass of: chemoreceptor cell
subclass of: serotonin secreting cell
subclass of: lung secretory cell
subclass of: Restriction
  on property: has part
  some values from: GO_0031045
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
subclass of: Restriction
  on property: capable of
  some values from: GO_0070483
subclass of: Restriction
  on property: has characterizing marker set
  some values from: CLM_1000043
definition: A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury.
RO_0002175: NCBITaxon 9606
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_1000223
has_exact_synonym: lung neuroendocrine cell
has related synonym: PNEC
in subset: cellxgene subset
in subset: human reference atlas
comment: The marker set CHGA, GRP can identify the Human cell type lung neuroendocrine cell in the Lung with a confidence of 0.94 (NS-Forest FBeta value).

Axiom
annotated source: pulmonary neuroendocrine cell
annotated property: definition
annotated target: A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury.
database_cross_reference: PMID:33355253
database_cross_reference: doi:10.3109/01902148209069653
database_cross_reference: doi:10.7554/eLife.78216

Axiom
annotated source: pulmonary neuroendocrine cell
annotated property: has_exact_synonym
annotated target: lung neuroendocrine cell
database_cross_reference: PMID:15018448

Axiom
annotated source: pulmonary neuroendocrine cell
annotated property: hasRelatedSynonym
annotated target: PNEC
database_cross_reference: PMID:33355253
has synonym type: OMO_0003000

Axiom
annotated source: pulmonary neuroendocrine cell
annotated property: comment
annotated target: The marker set CHGA, GRP can identify the Human cell type lung neuroendocrine cell in the Lung with a confidence of 0.94 (NS-Forest FBeta value).
database_cross_reference: https://doi.org/10.5281/zenodo.11165918

lung secretory cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002048
subclass of: secretory cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002048
definition: Any secretory cell that is part of some lung.
in subset: cellxgene subset

Axiom
annotated source: lung secretory cell
annotated property: definition
annotated target: Any secretory cell that is part of some lung.
database_cross_reference: FBC:Autogenerated

trophectodermal cell
type: Class
equivalent class: Class
  intersection of: extraembryonic cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004345
subclass of: extraembryonic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004345
subclass of: Restriction
  on property: develops into
  some values from: trophoblast cell
definition: An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange.
has_exact_synonym: trophectoderm cell

Axiom
annotated source: trophectodermal cell
annotated property: definition
annotated target: An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange.
database_cross_reference: PMID:22918806

smooth muscle cell of small intestine
type: Class
equivalent class: Class
  intersection of: enteric smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002108
subclass of: enteric smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002108
definition: A smooth muscle cell that is part of the small intestine.
database_cross_reference: FMA:15050
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_1000275
has_exact_synonym: non-striated muscle fiber of small intestine
in subset: cellxgene subset

Axiom
annotated source: smooth muscle cell of small intestine
annotated property: subClassOf
annotated target: enteric smooth muscle cell
is inferred: true

Axiom
annotated source: smooth muscle cell of small intestine
annotated property: definition
annotated target: A smooth muscle cell that is part of the small intestine.
database_cross_reference: GOC:tfm

Axiom
annotated source: smooth muscle cell of small intestine
annotated property: has_exact_synonym
annotated target: non-striated muscle fiber of small intestine
database_cross_reference: FMA:15050

smooth muscle fiber of duodenum
type: Class
equivalent class: Class
  intersection of: smooth muscle cell of small intestine
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002114
subclass of: smooth muscle cell of small intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001902
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002114
definition: A smooth muscle cell that is part of the duodenum.
database_cross_reference: FMA:15058
has_exact_synonym: non-striated muscle fiber of duodenum

Axiom
annotated source: smooth muscle fiber of duodenum
annotated property: subClassOf
annotated target: smooth muscle cell of small intestine
is inferred: true

Axiom
annotated source: smooth muscle fiber of duodenum
annotated property: definition
annotated target: A smooth muscle cell that is part of the duodenum.
database_cross_reference: GOC:tfm

Axiom
annotated source: smooth muscle fiber of duodenum
annotated property: has_exact_synonym
annotated target: non-striated muscle fiber of duodenum
database_cross_reference: FMA:15058

smooth muscle cell of large intestine
type: Class
equivalent class: Class
  intersection of: enteric smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000059
subclass of: enteric smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000059
definition: A smooth muscle cell that is part of the large intestine.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:15653
has_exact_synonym: non-striated muscle fiber of large intestine
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: smooth muscle cell of large intestine
annotated property: subClassOf
annotated target: enteric smooth muscle cell
is inferred: true

Axiom
annotated source: smooth muscle cell of large intestine
annotated property: definition
annotated target: A smooth muscle cell that is part of the large intestine.
database_cross_reference: GOC:tfm

Axiom
annotated source: smooth muscle cell of large intestine
annotated property: has_exact_synonym
annotated target: non-striated muscle fiber of large intestine
database_cross_reference: FMA:15653

smooth muscle cell of colon
type: Class
equivalent class: Class
  intersection of: enteric smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001155
subclass of: smooth muscle cell of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001155
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001278
definition: A smooth muscle cell that is part of the colon.
database_cross_reference: FMA:15663
has_exact_synonym: non-striated muscle fiber of colon

Axiom
annotated source: smooth muscle cell of colon
annotated property: definition
annotated target: A smooth muscle cell that is part of the colon.
database_cross_reference: GOC:tfm

Axiom
annotated source: smooth muscle cell of colon
annotated property: has_exact_synonym
annotated target: non-striated muscle fiber of colon
database_cross_reference: FMA:15663

smooth muscle cell of sigmoid colon
type: Class
equivalent class: Class
  intersection of: smooth muscle cell of colon
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001159
subclass of: smooth muscle cell of colon
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001159
definition: A smooth muscle cell that is part of the sigmoid colon.
database_cross_reference: FMA:17521
has_exact_synonym: non-striated muscle fiber of sigmoid colon

Axiom
annotated source: smooth muscle cell of sigmoid colon
annotated property: subClassOf
annotated target: smooth muscle cell of colon
is inferred: true

Axiom
annotated source: smooth muscle cell of sigmoid colon
annotated property: definition
annotated target: A smooth muscle cell that is part of the sigmoid colon.
database_cross_reference: GOC:tfm

Axiom
annotated source: smooth muscle cell of sigmoid colon
annotated property: has_exact_synonym
annotated target: non-striated muscle fiber of sigmoid colon
database_cross_reference: FMA:17521

smooth muscle cell of rectum
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001052
subclass of: smooth muscle cell of large intestine
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001052
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001278
definition: A smooth muscle cell that is part of the rectum.
database_cross_reference: FMA:17522
has_exact_synonym: non-striated muscle fiber of rectum
has_exact_synonym: smooth muscle fiber of rectum

Axiom
annotated source: smooth muscle cell of rectum
annotated property: definition
annotated target: A smooth muscle cell that is part of the rectum.
database_cross_reference: GOC:tfm

Axiom
annotated source: smooth muscle cell of rectum
annotated property: has_exact_synonym
annotated target: non-striated muscle fiber of rectum
database_cross_reference: FMA:17522

fibroblast of areolar connective tissue
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0006815
subclass of: fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0006815
definition: A fibroblast that is part of the areolar connective tissue.
database_cross_reference: FMA:261279

Axiom
annotated source: fibroblast of areolar connective tissue
annotated property: subClassOf
annotated target: fibroblast
is inferred: true

Axiom
annotated source: fibroblast of areolar connective tissue
annotated property: definition
annotated target: A fibroblast that is part of the areolar connective tissue.
database_cross_reference: GOC:tfm

fibroblast of tunica adventitia of artery
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007240
subclass of: CL_4052030
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007240
definition: A fibroblast that is part of the tunica adventitia of artery.
database_cross_reference: FMA:261285

Axiom
annotated source: fibroblast of tunica adventitia of artery
annotated property: definition
annotated target: A fibroblast that is part of the tunica adventitia of artery.
database_cross_reference: GOC:tfm

fibroblast of dense regular elastic tissue
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007846
subclass of: fibroblast
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002521
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007846
definition: A fibroblast that is part of the dense regular elastic tissue.
database_cross_reference: FMA:261287

Axiom
annotated source: fibroblast of dense regular elastic tissue
annotated property: definition
annotated target: A fibroblast that is part of the dense regular elastic tissue.
database_cross_reference: GOC:tfm

epicardial adipocyte
type: Class
subclass of: adipocyte
subclass of: cardiocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002348
definition: An adipocyte that is part of the epicardial fat.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:261293
has_exact_synonym: adipocyte of epicardial fat
has_exact_synonym: epicardial fat cell
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: epicardial adipocyte
annotated property: definition
annotated target: An adipocyte that is part of the epicardial fat.
database_cross_reference: GOC:tfm

Axiom
annotated source: epicardial adipocyte
annotated property: has_exact_synonym
annotated target: adipocyte of epicardial fat
database_cross_reference: FMA:261293

Axiom
annotated source: epicardial adipocyte
annotated property: has_exact_synonym
annotated target: epicardial fat cell
database_cross_reference: FMA:261293

adipocyte of epicardial fat of right ventricle
type: Class
equivalent class: Class
  intersection of: epicardial adipocyte
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002080
subclass of: epicardial adipocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002080
definition: An adipocyte that is part of the epicardial fat of right ventricle.
database_cross_reference: FMA:261297
has_exact_synonym: epicardial adipocyte of right ventricle
has_exact_synonym: epicardial fat cell of right ventricle

Axiom
annotated source: adipocyte of epicardial fat of right ventricle
annotated property: definition
annotated target: An adipocyte that is part of the epicardial fat of right ventricle.
database_cross_reference: GOC:tfm

Axiom
annotated source: adipocyte of epicardial fat of right ventricle
annotated property: has_exact_synonym
annotated target: epicardial adipocyte of right ventricle
database_cross_reference: FMA:261297

Axiom
annotated source: adipocyte of epicardial fat of right ventricle
annotated property: has_exact_synonym
annotated target: epicardial fat cell of right ventricle
database_cross_reference: FMA:261297

adipocyte of epicardial fat of left ventricle
type: Class
equivalent class: Class
  intersection of: epicardial adipocyte
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002084
subclass of: epicardial adipocyte
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002084
definition: An adipocyte that is part of the epicardial fat of left ventricle.
database_cross_reference: FMA:261300
has_exact_synonym: epicardial adipocyte of left ventricle
has_exact_synonym: epicardial fat cell of left ventricle
in subset: cellxgene subset

Axiom
annotated source: adipocyte of epicardial fat of left ventricle
annotated property: definition
annotated target: An adipocyte that is part of the epicardial fat of left ventricle.
database_cross_reference: GOC:tfm

Axiom
annotated source: adipocyte of epicardial fat of left ventricle
annotated property: has_exact_synonym
annotated target: epicardial adipocyte of left ventricle
database_cross_reference: FMA:261300

Axiom
annotated source: adipocyte of epicardial fat of left ventricle
annotated property: has_exact_synonym
annotated target: epicardial fat cell of left ventricle
database_cross_reference: FMA:261300

serous cell of epithelium of trachea
type: Class
equivalent class: Class
  intersection of: serous secreting cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001901
subclass of: tracheobronchial serous cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001901
definition: A serous secreting cell that is part of the epithelium of trachea.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:263078
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_1000330
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: serous cell of epithelium of trachea
annotated property: definition
annotated target: A serous secreting cell that is part of the epithelium of trachea.
database_cross_reference: GOC:tfm

serous cell of epithelium of bronchus
type: Class
equivalent class: Class
  intersection of: serous secreting cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002031
subclass of: tracheobronchial serous cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002031
definition: A serous secreting cell that is part of the epithelium of bronchus.
RO_0002175: NCBITaxon 9606
database_cross_reference: FMA:263080
database_cross_reference: https://cellxgene.cziscience.com/cellguide/CL_1000331
in subset: cellxgene subset
in subset: human reference atlas

Axiom
annotated source: serous cell of epithelium of bronchus
annotated property: definition
annotated target: A serous secreting cell that is part of the epithelium of bronchus.
database_cross_reference: GOC:tfm

transitional myocyte of interatrial septum
type: Class
equivalent class: Class
  intersection of: transitional myocyte
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002085
subclass of: transitional myocyte
subclass of: CL_2000022
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002085
definition: A transitional myocyte that is part of the interatrial septum.
database_cross_reference: FMA:263152

Axiom
annotated source: transitional myocyte of interatrial septum
annotated property: subClassOf
annotated target: transitional myocyte
is inferred: true

Axiom
annotated source: transitional myocyte of interatrial septum
annotated property: definition
annotated target: A transitional myocyte that is part of the interatrial septum.
database_cross_reference: GOC:tfm

transitional myocyte of interventricular septum
type: Class
equivalent class: Class
  intersection of: transitional myocyte
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002094
subclass of: transitional myocyte
subclass of: CL_2000022
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002094
definition: A transitional myocyte that is part of the interventricular septum.
database_cross_reference: FMA:263154

Axiom
annotated source: transitional myocyte of interventricular septum
annotated property: subClassOf
annotated target: transitional myocyte
is inferred: true

Axiom
annotated source: transitional myocyte of interventricular septum
annotated property: definition
annotated target: A transitional myocyte that is part of the interventricular septum.
database_cross_reference: GOC:tfm

Purkinje myocyte of interventricular septum
type: Class
equivalent class: Class
  intersection of: Purkinje myocyte
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002094
subclass of: Purkinje myocyte
subclass of: CL_2000022
definition: A Purkinje myocyte that is part of the interventricular septum.
database_cross_reference: FMA:263182