{"nbformat":4,"nbformat_minor":0,"metadata":{"colab":{"name":"ADN-1.ipynb","version":"0.3.2","provenance":[],"collapsed_sections":[]},"kernelspec":{"name":"python3","display_name":"Python 3"}},"cells":[{"metadata":{"id":"w0RXen0REXSb","colab_type":"text"},"cell_type":"markdown","source":["## **Structure et composition de l’ADN**\n","\n","\n","\n","---\n","\n","\n","Une chaîne d’ADN est valide  si elle n'est pas vide et si elle est formée exclusivement d’une combinaison arbitraire de nucléotides  \"a\" \"t\" \"g\" ou \"c\".\n","\n","La chaine brin, ci-dessous, correspond au gène antennapedia de la drosophile:\n","\n","\n"]},{"metadata":{"id":"qzQmPCgOEwCJ","colab_type":"code","colab":{}},"cell_type":"code","source":["# Programme\n","\n","brin=\"CGTCGGCGCACCCGAAATCGGAGGTTCGCTAGCGAGGTTCTCACAGTCAGAACTTTTCTTCTTATGGGTAGTATGATCAGAAGGCAACTAGGTCTATTCTCGTATGCTCCCATTCATAAATTGGATTATAATACAAACTACGCGAGCATGGGATGACTATGAGATCGAGTCTGTGAAAGTTAAGGGCGGTTAAGACTACAACGGTTATAGGTGCAATATCGTCAAGGCGAAGCCTCGTTATTTGTTCTCCGATCGTCTTGTGGTCTACTAGCAATGTAAACCCCGATCACGCAACGGGTCCTACGCCCCTACGCTGGACGATGATTAAATTCACCGAATGTTTAACCACGCTGTTGAAGGCACATCGTATGAACTGTGGACAAGGGCTAGTTGCCCGGGGGGTACATTCGTAGGCCATATGCCGACAAAAATGCTCATAACAAACACAGCGCGCTGGGTAGAGATCTGGAGTACATTAATGTGAGTACTTTGATGGGAGCGACTCACGACTATACGTGTCGCGTCGTGATCGGAAACTACTCAGCGGTCTATCTATTTGCGTAGTAAAATCAAGGGGCAAAAACTCTAATAGTTGAACAAGGTGCGGATCCACATATTCTAGCTCATCCCATGTATCGTATAAAGCAAACACACCCGGACTGCTTCGATCAGTAATACCGACAACCGCATGCTGTCTAACAAACCCGATAGTAACGGAATGTCGCTCCCAAGATGTATAGAACTAAGCTGCACCACAGGTCTGATACATTTTTTGCCGGCGATAAGAAATTACCGGCAGTTGGCGAATTTAGTGTCCGGGGTAGCATAAAGTGGGAATGTCGCTAGATTGAATGTACGCAACTAATTCGGGAGGTAGATGCATATGTGGGAGGCGGGTCAGCAGCTGCAATTGGTAAGTCCCGTTTTACAGGACTGTACGAACACGTCCTACCATGATCGTCGTATCTACTGCGGAGAGCGTTGATTTTGGGGCGTACGAGACGAATCCCCACCAAAGTAGGAGATGTCGAGCTCGCATGGAGAGGATCGTGATTACCGTAGCATTGGCTGTTAGGAGCGTTGAAAGGTTGTTTATTGCATTTAAGCGGTAAGCCATCGAGCGAGTGGATACGTCGGAGGCGTATGCCGCACGCCTATAGAGGGGCAAGGGTGACCATTCAAAGTACTCTAGTTGTTATGTTCTATCGATATCATCGACTGCATCTGTGTACGGGGACGCGGCACTACCTAGGGGTTTCGAGGACTTGTGCCGCTATCCGTGCGGGCCGAATCATTGCGATATTGCTGCATTGTATTATGGCACGCACTCGTTAACCATGACCCACGCGATTAGTGTGGGGTTGATGCGACGAAAAGAGCTATAGACTAGTTCGAGAAGCGCAAAGATTATGCCGTTCACGCAGCCAAGAAACGTTCCGGAGTTTCCTGACGTCGTCACTAGGAAGCCCTATTGGGACACCGGCTCTGTTCCTCGCACCTCATAGGAGTCCGCGCAACTTTCCGCACTAGCACCCTTAATTCGTCACCGTTCCGCTACCTGTTCGAATCTGGAGACCTATCTGGTGGAACGCGGTAGGTGGAGTTTTATTCCGGCGTTCCCGAGTCGCTCCGTGGATTAATTGTCTGCCTGTATTATGTCTATAGCCTGGCCCTGAAAGCGGCTACCTTAGGCTCCTGCTATAAATCACTGTGATTTTAAACCCCTCGGGCAATTTTACTGTACAGCTAACGGGATCCTTTCCGTAATCTAGCCGTAGTACTCAAGTGAAGTGCTAAGGTATTTGAGTTTCTGGTCGAAGGCGCTTTGGCACTACAATTGCTCTAACGAACCGGACTGTCATGAGCTTCCCCGGACCCTTGACGATCATTCTTGGGGCTGGGTGGTTAGACAGCCTTATCGGGCTTGACCCTCTGACCATTAGTAGATATACTCTGACCTTGAGGATATACGTTGTCCCGCACCTCAAAGGGGGATATTGGAAATCCCATCCCTTCCAATAAAACGAGCGCACGCCCGTATATAGTACCAACCTTACCAGTCACATATGATGTTTATGGGATTAACGCAGGTGACCGCAGGCAAAATAAGGAAATGCACGATTGGTTTGAAGCCGCGATAAGTCGCTGACAGTATAGTGGTCGTTACTTACACTTCTCGACTCGTAGAAAGGCCAAGGCCTCTCTACGAAGTAAAGCAGACTCGAACATGGAAACTCACGAGGATCCAGGCGAAGCTGATGTTGACTACAAACGCTGCCGAATGGCTAGTTATGTCTGTGAGCCTACTACTGCTGGAGTGGACGCCTAATTTGAGTTGGCGTTAAGGCCGTATGGGCAGATAGGGGGGAGAGGCCTACGACGGGTAAGTGATGAAGGTCGCATCGGTGCGCTTGGACATAGCCCAAGCCGCGAGGATTAGCGTGGTTACTAACGCGATACAGTTACTTTAGTGAAGTTTGTAGGATTGTGAGCTTTCCTCAAGGGGCCGATCCGTAAATTAAGCGGAATATGGAGATTCACTCGTATGTGGAATGATGCGCCAGGTCGACGTATGTTGATTTAATGTACTATCGGGATAACTGGACGCATACCGCCGACTCAGTGCGGTTGTGCCTTGGGCGTCGCCCCCCTGCTTCTGTAGGGTCATGACGCTCCGACATCTGCTGGGCTCTCTAACCGAGACGGGCTCTATGCAAGGTTTCCGTAAAGGGGGAGTGAAGGTATATACCGAAGCTAATTGAAACCAGGAGGACGACGGTAAAATCCCAGCCAGGACTCTGGACGCTATTGGGTCTAGGCAAGCATACCGAGAACGCCCGATAGGTTACTCACGTTGTGACGATACGATTGCGGTGGAACGTACCAATCTTAAAGGCGTACTGTGGTTAAAGCCTGTGACGGTATCATGGCACAATTTGTCAAGCTGCGCAACACGTCTGAGGGACAGCCGCCTTCCTGAACCACGTCGTGCCTACGCTGTACGCGCTGGGGTACGGTCACTAGGCTCGGCACGGTAAATGTCGAGCGCAATACGCGGAACGGCAGGATCAACCATTACCGTGTAGCTGATACTCTGTGTGTTATCTCTACATTCTGATGTTTCATTTTAGAGCTTAGGTGCATCCATCTTTGAACCCAGCTAACCGGCGGTGTCCGTTCACCCTAATGGCGCTGAACCTCCGGTCCGGGTTTATCAAGGAAAAATCCGAACTCGTATGCATCGCGCGTCGTCACAAAGTTCTTTGAGATGCTTCAAGGTTTGATCCTTGGGCGATTTACTGGCTTTACACTATCGACGGAATTATCCCAACCGGACTTATGTATACATTTCTTACACAGCTCGTTTCGGCCAGACCCCGTTTCGTATAGCTAATGTTACGATATTTTCCTATGGGGACGATGACGCAATTAAGGAAAAAGCATGATGCTAGATAGCACCCCCACGTAGGAAACTGTAGGATACAGGTCTGTAGCCGCACAAAGAAACCATCTTACAACTACAACAGGGGCAGCCTGTCAAGATGGTCAGCACGTTATTACTTTGGCCCGTGCCGCGAGCAATATAAAGTATTAGGTGCGACATAGTAAGAGCTTTCAGTTGCAGATAGTTGTCGGGGAGCCCGGTGAGTGTAACTCGTAGTGATGGCTCAGTTCGACCCACATTGGAAACTCGGTTAGTACAAATCACTTGGATTTCGCCTGAGGACCGTACAATGCCTGCCACCTAAACAGTCATGGAGCTCAGGATCACCTATAGGGTGACATGTTGTCAACGCGCCAATGACAGGAGGGGATCTCTGAACTTCGCGCCAATCAGCTTATAAACTACTATCTTCCGATAGCACCATCCAGAGACTTCCGCGTATGAGAGAACAACTGCCATTGTCCCTAAGGGACTGGCCGCATAAGAAGGACCCCATTGTAACTCAACGTAAGTGTTCGACGGCTTGCATTTCTTGATTAGATCGAGCACGTCCCGTCGGGACTGTATTTGTATTGCTCCTAGTAGAACACGCATGGCAGCACTATGTTCTTTCACCCCATCGTTCGGTGATCGGATTATACCCAACGATATCTATTTGACATTACATTCGTAACCTATAACTTCCTTTGCAGTGCTTTGCCTTTGCGAGTACGAAACTCGGCACATTTGGCAGCCTACAGACAAACCGACCTGGAGTTTCTCGACAGGCGCTAAACTTGTTTGGTGGCAGTGCGCAGCGCTCCGTACCACCACGCGTCGGATTGATCCGGGCCAATGTCATGGCCGGGGCTGATACTTCGTTAGCGTGTAAGAACAGGCGCTCCTGAAGTACCTACGATACGTTCACGCATGCAAACGAGCCCTTAGAGCCTGCCCGACGTCCGTTAATATGGCGAGCAGAAGGCATAAATGCTGTTAATCAAGCTTCCTGTACTCCCGCTTATTTACTACTGTGCCAAGTGGAGTTAATGTTGAGACAAGGACTTGCTTGGTGACCCAGCGGGCTACAACATCCTGAACTTGCCCATGGGTCCGGAGTGTTTCTAGGGGACAAGGGTTAACAGTATTACCGTGATATTTTCTAACCACGTCAGCCCAATTTAATTCGAAACATGTCGAGTGTCCACTTATGGGCTACCAAGCTCTAGCGAGTGTAATCTCCGCCTAATGCTCCCCCTAGGAACGTCAGAACGGGACGCGCGTTGCGTACAGAGAGTTCTGAAATCGGCACTATAAGTGATTAACTGGGTACCGGTCGTTCAGCATCAGAAGCGTCCATTAACCGTGAGCGCGGAAGATACTGCAGGCTTCATCTCCTCGAGTAATTTTGATGTATGGCATGAATATATACCGTGCATGTGGTTGCTGGCATGACCCTGAAAGTCAGAGACTAGTTCCCAGGCCTCGTCAGCTCCTCCCGAGCGCTCACGTCACGTTGATTAATGTCTGCTTGGGTGGTCTGCCCGTAGCCAGAACTTGGTCGGTATTCCGCACGCACTAAGGCGTGTCATAGAAGCGTCCCTGCTCACCGCGGCGCAAGGTGAGCGTACATCTTGCCAGGACACAGGTACGGAGAATCCTATCGGGAAGGAGGCCATAACAGTGAGTACAGGTTCTTAACCCAAACATTCCCTTGGCGGACTACAGAGTAAGACCGGCAACAGCTAAACGAGATTGCCTAGACTTAACATACTCAGTGATAGTACTCTCCAGGATTTGCCCCGTTAGCAAGTTCGACAAGCTGCGAGCGGATCTCATAGATATCACGACGGGCTTCTCAATCGTCGTCTAACCAAAGCTACCTATTCGTTCCCCGGGCGACTAGGTTTCTGGGGCCCGGTATGGTAAATTTGTATTCGTTATGGCTTTGGGGAGTAAGCACCTAAAAACTGACCTCAGGCCTGTAAATATTCGTAACCCAACACCGCTGGTCTGTGAGGCGAAAGGTCGCCGGCGCTGCTTGTCGAAGTGGTAACTTGGCTTCTTGCATGACCCATGGATATTTCATAAAGGGAAGGCTCGACACAATCGCACATCTGACAGAGTAGACTGATTGGTCCGTCGCGTTGTGAGAATTGGTCCAGTAAGCCCAAGTCTTATACGTCCGTAGTTGATGCGGTGGAACCCATTGAGAGACGAGAATCCCTGGTGATCAAGGCAAGGTGTACCACATCAAGTAATCCCGTAAAGGTCCTTGCCCTACAGTGAATTTGCCAGCCAGTCTCGGGATTACCATATAACCTCCGTATCCGATCTTATGGAAACTGGGAGAAGGTAGACCGTGGTAACTACCTAGAAGTCGCAGTCACGGAGTACCCCGTGACATCCATATGGGACTTAGGCCGCACTATAACGGCCAGCCATTCAAAGGAGTATTTAGTCACCCGCATCTGATCGGACGTAGTGTCTTCAGCGCTACGCCTTGTTCGCAAACATTGCTAAGGTGTCCTACTCTCCCCGGATAACCAAAGGAGAGGCCAGATAAGCTTCATCTGCCGCAAGAACAAGCGCGAACTCAGTCCCGCTGGTTATGGGGTCACTTGCTCTTCACTCCCCCTCCAGGGGGGAACTCGTATTGGCCGATCGGGATTGGAGTAGAGGTGATTCAAGGTAAACCGACATTTCGTGCGACTCTATGGAGTATACAGAAATTACTGGACTCGGAGAGGCCCTAGCGACCCGAACCGATATAGCAAGGATTAAGGCTTTCAGCAGTTACGTTTCCCATTCGATACGCGACTCGATGGCCGAGTAAAGACACAGAGAATTCCGGGTAAACTTAATCTGCATGTTGATCCAATCTACTCTCCGACGTCCTCGAGAAGTACTGGAAGGCTCCCTGAGATAAACACACGCAACTTGTCCTCACTAAATGTGCAACAACTGTGAAAAAAG\"\n"],"execution_count":0,"outputs":[]},{"metadata":{"id":"eF4KlR68ExNe","colab_type":"text"},"cell_type":"markdown","source":["1. Écrire une fonction proportion qui reçoit deux arguments, une chaîne  c  et la séquence recherchée et qui retourne la proportion de la séquence dans la chaîne."]},{"metadata":{"id":"g1H88KeWE5Km","colab_type":"code","colab":{}},"cell_type":"code","source":["# Programme\n","\n"],"execution_count":0,"outputs":[]},{"metadata":{"id":"FS-dVq2wI0b_","colab_type":"text"},"cell_type":"markdown","source":["\n","\n","\n","2. Ecrire un programme en Python qui demande à l’utilisateur la séquence d’un brin d’ADN et affiche la séquence complémentaire.\n","\n","    Par exemple, si l’utilisateur saisit la séquence suivante :\n","\n","   TATCGATACAAT le programme doit afficher ATAGCTATGTTA\n","\n","\n","\n"]},{"metadata":{"id":"Xh3Y8VS8_7Zw","colab_type":"code","colab":{}},"cell_type":"code","source":["# Programme\n","\n","\n","\n"],"execution_count":0,"outputs":[]},{"metadata":{"id":"nmtzRKsT_-Ca","colab_type":"text"},"cell_type":"markdown","source":["3. Ecrire le programme en Python qui :\n"," \n","\n","* génère une séquence aléatoire de 20 nucléotides\n","\n","* affiche cette séquence (horizontalement)\n","\n","* modifie aléatoirement un nucléotide\n","\n","* affiche la séquence modifiée (mutée)"]},{"metadata":{"id":"YFYz6X-U4aJ5","colab_type":"code","colab":{}},"cell_type":"code","source":["# Programme:\n","\n","\n","\n"],"execution_count":0,"outputs":[]},{"metadata":{"id":"mmYJxpch4Uga","colab_type":"text"},"cell_type":"markdown","source":["Une chaîne d’ADN est valide  si elle n'est pas vide et si elle est formée exclusivement d’une combinaison arbitraire de nucléotides  \"a\" \"t\" \"g\" ou \"c\".\n","\n","4. Écrire une fonction valide qui renvoie True si la chaine brin est valide, False sinon.\n"]},{"metadata":{"id":"Ia35nMC4ADz3","colab_type":"code","colab":{}},"cell_type":"code","source":["# Programme:\n","\n","\n","\n"],"execution_count":0,"outputs":[]}]}