format-version: 1.2 data-version: releases/2026-03-19 subsetdef: 1_STAR "" subsetdef: 2_STAR "" subsetdef: 3_STAR "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" subsetdef: blood_and_immune_upper_slim "" subsetdef: cell_quality "" subsetdef: cellxgene_subset "" subsetdef: common_anatomy "" subsetdef: cumbo "" subsetdef: cyclostome_subset "" subsetdef: defined_by_ordinal_series "" subsetdef: developmental_classification "" subsetdef: disposition_slim "" subsetdef: early_development "" subsetdef: efo_slim "" subsetdef: emapa_ehdaa2 "" subsetdef: eye_upper_slim "" subsetdef: functional_classification "" subsetdef: general_cell_types_upper_slim "" subsetdef: gocheck_do_not_annotate "" subsetdef: gocheck_obsoletion_candidate "" subsetdef: goslim_agr "" subsetdef: goslim_candida "" subsetdef: goslim_chembl "" subsetdef: goslim_drosophila "" subsetdef: goslim_euk_cellular_processes_ribbon "" subsetdef: goslim_flybase_ribbon "" subsetdef: goslim_generic "" subsetdef: goslim_metagenomics "" subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_plant_ribbon "" subsetdef: goslim_pombe "" subsetdef: goslim_prokaryote "" subsetdef: goslim_prokaryote_ribbon "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" subsetdef: homology_grouping "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_ontology "" subsetdef: http://purl.obolibrary.org/obo/valid_for_gocam "" subsetdef: human_reference_atlas "" subsetdef: human_subset "" subsetdef: inconsistent_with_fma "" subsetdef: kidney_upper_slim "" subsetdef: location_grouping "" subsetdef: major_organ "" subsetdef: mouse_subset "" subsetdef: mpath_slim "" subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" subsetdef: uberon_slim "" subsetdef: ubprop:upper_level "" subsetdef: unverified_taxonomic_grouping "" subsetdef: upper_level "" subsetdef: value_slim "" subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: common_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" synonymtypedef: HOMOLOGY "" synonymtypedef: human "" synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" synonymtypedef: INN "" synonymtypedef: IUPAC_NAME "" synonymtypedef: MISSPELLING "" synonymtypedef: OMO:0003000 "" synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "" synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PRO-short-label "" synonymtypedef: scientific_name "" synonymtypedef: SENSU "" synonymtypedef: syngo_official_label "" synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" synonymtypedef: vertebrate "" idspace: dce http://purl.org/dc/elements/1.1/ idspace: dcterms http://purl.org/dc/terms/ idspace: doap http://usefulinc.com/ns/doap# idspace: foaf http://xmlns.com/foaf/0.1/ idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# idspace: pav http://purl.org/pav/ idspace: protege http://protege.stanford.edu/plugins/owl/protege# idspace: skos http://www.w3.org/2004/02/skos/core# idspace: sssom https://w3id.org/sssom/ idspace: swrl http://www.w3.org/2003/11/swrl# idspace: swrla http://swrl.stanford.edu/ontologies/3.3/swrla.owl# idspace: swrlb http://www.w3.org/2003/11/swrlb# ontology: fovt property_value: dcterms-license http://creativecommons.org/publicdomain/zero/1.0/ property_value: dcterms:description "None" xsd:string property_value: dcterms:description "These are the terms that are improted for FOVT to describe vertebrate traits." xsd:string property_value: dcterms:title "FuTRES Ontology of Vertebrate Traits" xsd:string property_value: owl:versionInfo "2026-03-19" xsd:string [Term] id: BCO:0000003 name: observing process def: "A process in which a person or machine sees or detects a material entity and selects it as worthy of observation, and which has as output an information content entity about the selected material entity." [] comment: An observing process is distinguished from a specimen collecting process in by having an information content entity as an output rather than a specimen. The information artifact may be written or recorded or just be stored in someone's head (specifically depenedent upon that person). In the context of a taxonomic inventory, an observing process may be called a sighting, which is an ad hoc reporting of, typically, a single taxon occurrence, usually motivated by rarity, individual interest in the taxon, or atypicality of circumstances. is_a: COB:0000035 ! completely executed planned process relationship: OBI:0000293 BFO:0000040 ! has_specified_input material entity relationship: OBI:0000299 IAO:0000030 ! has_specified_output information content entity property_value: BCO:0000057 "sighting" xsd:string property_value: dce:creator "Biocode Commons Ontology Hackathon" xsd:string property_value: editor_note "This class replaces class bco_0000003, which was made obsolete because of identifier format." xsd:string property_value: editor_note "We are having conversation with OBI developers about how this term relates to OBI:assay (). Is it equivalent, broader, narrower? What does it mean to be the input to an observation." xsd:string property_value: IAO:0000112 "A trip camera capture of an image of a jaguar is an observation, because it is \"selected\" by the camera as worthy of obsevation simply by virtue of moving in front of the camera." xsd:string property_value: IAO:0000112 "Observing and recording the presence or absence of butterflies during a transect walk." xsd:string property_value: IAO:0000112 "Seeing three pelicans flying overhead on Christmas day and report them as part of the Christmas Bird Count." xsd:string property_value: IAO:0000114 IAO:0000125 [Term] id: BCO:0000046 name: material target of observation role def: "A role that is borne by some material entity and is realized by the material entity being the input of an observing process." [] is_a: BFO:0000023 ! role intersection_of: BFO:0000023 ! role intersection_of: BFO:0000054 BCO:0000003 ! realized in observing process relationship: BFO:0000054 BCO:0000003 ! realized in observing process property_value: dce:creator "Biocode Commons Ontology Hackathon" xsd:string property_value: editor_note "This term replaced bco_0000046, which was made obsolete because of incorrect identifier format." xsd:string property_value: IAO:0000112 "the role borne by a bird during a Christmas Bird Count" xsd:string property_value: IAO:0000114 IAO:0000125 [Term] id: BFO:0000001 name: entity disjoint_from: oboInOwl:ObsoleteClass ! Obsolete Class property_value: BFO:0000179 "entity" xsd:string property_value: BFO:0000180 "Entity" xsd:string property_value: editor_note "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string property_value: editor_note "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"} property_value: IAO:0000112 "Julius Caesar" xsd:string property_value: IAO:0000112 "the Second World War" xsd:string property_value: IAO:0000112 "Verdi’s Requiem" xsd:string property_value: IAO:0000112 "your body mass index" xsd:string property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000002 name: continuant def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." [] is_a: BFO:0000001 ! entity disjoint_from: BFO:0000003 ! occurrent relationship: part_of BFO:0000002 {all_only="true"} ! continuant property_value: BFO:0000179 "continuant" xsd:string property_value: BFO:0000180 "Continuant" xsd:string property_value: editor_note "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string property_value: editor_note "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"} property_value: IAO:0000111 "continuant" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000003 name: occurrent def: "An entity that has temporal parts and that happens, unfolds or develops through time." [] is_a: BFO:0000001 ! entity relationship: part_of BFO:0000003 {all_only="true"} ! occurrent property_value: BFO:0000179 "occurrent" xsd:string property_value: BFO:0000180 "Occurrent" xsd:string property_value: editor_note "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region" xsd:string property_value: editor_note "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players." xsd:string property_value: editor_note "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000006", comment="per discussion with Barry Smith"} property_value: editor_note "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000012"} property_value: IAO:0000589 "processual entity (BFO)" xsd:string property_value: IAO:0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/077-002"} property_value: IAO:0000601 "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: IAO:0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000004 name: independent continuant def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." [] def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} comment: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000004 {all_only="true"} ! independent continuant property_value: BFO:0000179 "ic" xsd:string property_value: BFO:0000180 "IndependentContinuant" xsd:string property_value: IAO:0000112 "a chair" xsd:string property_value: IAO:0000112 "a heart" xsd:string property_value: IAO:0000112 "a leg" xsd:string property_value: IAO:0000112 "a molecule" xsd:string property_value: IAO:0000112 "a spatial region" xsd:string property_value: IAO:0000112 "an atom" xsd:string property_value: IAO:0000112 "an orchestra." xsd:string property_value: IAO:0000112 "an organism" xsd:string property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string property_value: IAO:0000112 "the interior of your mouth" xsd:string property_value: IAO:0000589 "anatomical entity (BFO)" xsd:string property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000006 name: spatial region is_a: BFO:0000141 ! immaterial entity property_value: editor_note "BFO 2 Reference: Spatial regions do not participate in processes." xsd:string [Term] id: BFO:0000015 name: process def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." [] def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. is_a: BFO:0000003 ! occurrent equivalent_to: http://rs.tdwg.org/dwc/terms/Event ! Event property_value: BFO:0000179 "process" xsd:string property_value: BFO:0000180 "Process" xsd:string property_value: editor_note "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string property_value: IAO:0000112 "a process of cell-division, \\ a beating of the heart" xsd:string property_value: IAO:0000112 "a process of meiosis" xsd:string property_value: IAO:0000112 "a process of sleeping" xsd:string property_value: IAO:0000112 "the course of a disease" xsd:string property_value: IAO:0000112 "the flight of a bird" xsd:string property_value: IAO:0000112 "the life of an organism" xsd:string property_value: IAO:0000112 "your process of aging." xsd:string property_value: IAO:0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000016 name: disposition is_a: BFO:0000017 ! realizable entity disjoint_from: BFO:0000023 ! role property_value: BFO:0000179 "disposition" xsd:string property_value: BFO:0000180 "Disposition" xsd:string property_value: editor_note "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type." xsd:string property_value: IAO:0000112 "an atom of element X has the disposition to decay to an atom of element Y" xsd:string property_value: IAO:0000112 "certain people have a predisposition to colon cancer" xsd:string property_value: IAO:0000112 "children are innately disposed to categorize objects in certain ways." xsd:string property_value: IAO:0000112 "the cell wall is disposed to filter chemicals in endocytosis and exocytosis" xsd:string property_value: IAO:0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: IAO:0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000017 name: realizable entity def: "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." [] is_a: BFO:0000020 ! specifically dependent continuant is_a: COB:0000502 ! characteristic disjoint_from: BFO:0000019 ! quality relationship: part_of BFO:0000017 {all_only="true"} ! realizable entity property_value: BFO:0000179 "realizable" xsd:string property_value: BFO:0000180 "RealizableEntity" xsd:string property_value: IAO:0000112 "the disposition of this piece of metal to conduct electricity." xsd:string property_value: IAO:0000112 "the disposition of your blood to coagulate" xsd:string property_value: IAO:0000112 "the function of your reproductive organs" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the role of this boundary to delineate where Utah and Colorado meet" xsd:string property_value: IAO:0000117 "https://orcid.org/0000-0001-8815-0078" xsd:string property_value: IAO:0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: IAO:0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000019 name: quality is_a: BFO:0000020 ! specifically dependent continuant relationship: part_of BFO:0000019 {all_only="true"} ! quality property_value: BFO:0000179 "quality" xsd:string property_value: BFO:0000180 "Quality" xsd:string property_value: IAO:0000112 "the ambient temperature of this portion of air" xsd:string property_value: IAO:0000112 "the color of a tomato" xsd:string property_value: IAO:0000112 "the length of the circumference of your waist" xsd:string property_value: IAO:0000112 "the mass of this piece of gold." xsd:string property_value: IAO:0000112 "the shape of your nose" xsd:string property_value: IAO:0000112 "the shape of your nostril" xsd:string property_value: IAO:0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: IAO:0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000020 name: specifically dependent continuant def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." [] def: "b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/131-004"} def: "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000020 {all_only="true"} ! specifically dependent continuant property_value: BFO:0000179 "sdc" xsd:string property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string property_value: editor_note "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000005", comment="per discussion with Barry Smith"} property_value: IAO:0000111 "specifically dependent continuant" xsd:string property_value: IAO:0000112 "of one-sided specifically dependent continuants: the mass of this tomato" xsd:string property_value: IAO:0000112 "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates." xsd:string property_value: IAO:0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key" xsd:string property_value: IAO:0000112 "the disposition of this fish to decay" xsd:string property_value: IAO:0000112 "the function of this heart: to pump blood" xsd:string property_value: IAO:0000112 "the mutual dependence of proton donors and acceptors in chemical reactions [79" xsd:string property_value: IAO:0000112 "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction" xsd:string property_value: IAO:0000112 "the pink color of a medium rare piece of grilled filet mignon at its center" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the shape of this hole." xsd:string property_value: IAO:0000112 "the smell of this portion of mozzarella" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl property_value: IAO:0000602 "(iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/131-004"} property_value: IAO:0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000023 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." [] is_a: BFO:0000017 ! realizable entity property_value: BFO:0000179 "role" xsd:string property_value: BFO:0000180 "Role" xsd:string property_value: editor_note "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives." xsd:string property_value: IAO:0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married." xsd:string property_value: IAO:0000112 "the priest role" xsd:string property_value: IAO:0000112 "the role of a boundary to demarcate two neighboring administrative territories" xsd:string property_value: IAO:0000112 "the role of a building in serving as a military target" xsd:string property_value: IAO:0000112 "the role of a stone in marking a property boundary" xsd:string property_value: IAO:0000112 "the role of subject in a clinical trial" xsd:string property_value: IAO:0000112 "the student role" xsd:string property_value: IAO:0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: IAO:0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000031 name: generically dependent continuant def: "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time." [] def: "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} is_a: BFO:0000002 ! continuant property_value: BFO:0000179 "gdc" xsd:string property_value: BFO:0000180 "GenericallyDependentContinuant" xsd:string property_value: IAO:0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity." xsd:string property_value: IAO:0000112 "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop" xsd:string property_value: IAO:0000112 "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule." xsd:string property_value: IAO:0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000034 name: function is_a: BFO:0000016 ! disposition property_value: BFO:0000179 "function" xsd:string property_value: BFO:0000180 "Function" xsd:string property_value: editor_note "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc." xsd:string property_value: IAO:0000112 "the function of a hammer to drive in nails" xsd:string property_value: IAO:0000112 "the function of a heart pacemaker to regulate the beating of a heart through electricity" xsd:string property_value: IAO:0000112 "the function of amylase in saliva to break down starch into sugar" xsd:string property_value: IAO:0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: IAO:0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000040 name: material entity def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." [] is_a: BFO:0000004 ! independent continuant disjoint_from: BFO:0000141 ! immaterial entity property_value: BFO:0000179 "material" xsd:string property_value: BFO:0000180 "MaterialEntity" xsd:string property_value: editor_note "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string property_value: editor_note "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string property_value: editor_note "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string property_value: editor_note "Elucidation: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." xsd:string property_value: IAO:0000111 "material entity" xsd:string property_value: IAO:0000112 "a flame" xsd:string property_value: IAO:0000112 "a forest fire" xsd:string property_value: IAO:0000112 "a human being" xsd:string property_value: IAO:0000112 "a hurricane" xsd:string property_value: IAO:0000112 "a photon" xsd:string property_value: IAO:0000112 "a puff of smoke" xsd:string property_value: IAO:0000112 "a sea wave" xsd:string property_value: IAO:0000112 "a tornado" xsd:string property_value: IAO:0000112 "an aggregate of human beings." xsd:string property_value: IAO:0000112 "an energy wave" xsd:string property_value: IAO:0000112 "an epidemic" xsd:string property_value: IAO:0000112 "the undetached arm of a human being" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ido.owl property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000141 name: immaterial entity is_a: BFO:0000004 ! independent continuant property_value: editor_note "BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10" xsd:string [Term] id: BSPO:0000000 name: left side namespace: spatial def: "The side of an organism that is left of the sagittal plane." [BSPO:cjm] synonym: "left" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: left_of BSPO:0000007 ! right side relationship: starts_axis BSPO:0000017 ! left-right axis [Term] id: BSPO:0000005 name: anatomical surface namespace: spatial def: "A 2D surface of an anatomical continuant." [BSPO:cjm] comment: to be merged into CARO synonym: "surface" EXACT [] xref: FMA:24137 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000007 name: right side namespace: spatial def: "The side of an organism that is right of the sagittal plane." [BSPO:cjm, BSPO:wd] synonym: "right" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000017 ! left-right axis [Term] id: BSPO:0000009 name: midsagittal plane namespace: spatial def: "Sagittal plane that divides bilateral body into equal left and right parts." [BSPO:mah] comment: only in bilaterally symmetrical organisms synonym: "median plane" RELATED [] synonym: "median sagittal plane" EXACT [FMA:74563] synonym: "midline plane" EXACT [] synonym: "midsagittal section" EXACT [] xref: FMA:74563 is_a: BSPO:0000417 ! sagittal plane [Term] id: BSPO:0000010 name: anatomical axis namespace: spatial def: "A straight line through space, intersecting an anatomical entity." [BSPO:cjm] comment: Axis directions are defined in terms of axes. xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG is_a: CARO:0000008 ! anatomical line relationship: passes_through CARO:0000000 ! anatomical entity [Term] id: BSPO:0000013 name: anterior-posterior axis namespace: spatial def: "An axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm] comment: In sponges, AP is used to indicate the direction of movement [in larval stage] (as it is in other metazoans that move, e.g., the basal bilaterians). [PM] synonym: "A-P axis" EXACT [] synonym: "anteroposterior axis" EXACT [] synonym: "AP axis" EXACT [] synonym: "cephalocaudal axis" NARROW [http://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "craniocaudal axis" NARROW vertebrate [] synonym: "longitudinal axis" RELATED [] synonym: "rostral/caudal" NARROW vertebrate [] synonym: "rostrocaudal axis" NARROW vertebrate [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000018 ! transverse plane relationship: approximately_perpendicular_to BSPO:0000016 ! dorsal-ventral axis relationship: orthogonal_to BSPO:0000018 ! transverse plane [Term] id: BSPO:0000015 name: proximal-distal axis namespace: spatial def: "An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal)." [BSPO:curators, http://en.wikipedia.org/wiki/Anatomical_terms_of_location] comment: In some communities, proximal and distal are used when specifying the position of parts of elements that are contained within the body, such as gill arches or vertebral spines. In these cases, use of the classes medial-lateral axis or medial-external axis are more appropriate. synonym: "proximal/distal" EXACT [] synonym: "proximodistal" EXACT [] is_a: BSPO:0000010 ! anatomical axis [Term] id: BSPO:0000016 name: dorsal-ventral axis namespace: spatial def: "An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body." [BSPO:curators] synonym: "anterior-posterior axis" NARROW human [] synonym: "D-V axis" EXACT [] synonym: "dorsoventral axis" EXACT [] synonym: "DV axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000019 ! horizontal plane relationship: orthogonal_to BSPO:0000019 ! horizontal plane [Term] id: BSPO:0000017 name: left-right axis namespace: spatial def: "An axis that bisects an organism from left to right sides of body, through a sagittal plane." [BSPO:cjm] synonym: "dextro-sinister axis" EXACT [] synonym: "L-R axis" EXACT [] synonym: "left to right axis" EXACT [] synonym: "LR axis" EXACT [] synonym: "R-L axis" EXACT [] synonym: "right to left axis" EXACT [] synonym: "right-left axis" EXACT [] synonym: "RL axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000417 ! sagittal plane relationship: orthogonal_to BSPO:0000417 ! sagittal plane [Term] id: BSPO:0000018 name: transverse plane namespace: spatial def: "Anatomical plane that divides body into anterior and posterior parts." [BSPO:mah] synonym: "axial plane" EXACT [] synonym: "axial section" EXACT [] synonym: "cross-section" RELATED [] synonym: "transverse section" EXACT [] xref: FMA:12247 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000019 name: horizontal plane namespace: spatial def: "Anatomical plane that divides bilateral body into dorsal and ventral parts." [BSPO:mah] synonym: "coronal section" RELATED [] synonym: "frontal plane" EXACT [] synonym: "frontal section" RELATED [] synonym: "horizontal anatomical plane" EXACT [FMA:52810] synonym: "horizontal section" EXACT [] xref: FMA:52810 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000027 name: antero-ventral region namespace: spatial def: "Anatomical region that overlaps the anterior and ventral regions of a body or body part." [BSPO:wd] synonym: "anteroventral region " EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-06-15T01:04:59Z [Term] id: BSPO:0000028 name: postero-lateral region namespace: spatial def: "Anatomical region that overlaps the posterior and lateral regions of the body or body part." [BSPO:wd] synonym: "posterolateral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-06-15T01:06:01Z [Term] id: BSPO:0000029 name: antero-lateral region namespace: spatial def: "Anatomical region that overlaps the anterior and lateral regions of a body or body part." [BSPO:wd] synonym: "anterolateral region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-06-15T01:07:18Z [Term] id: BSPO:0000035 name: postero-ventral region namespace: spatial def: "Anatomical region that overlaps the posterior and ventral regions of a body or body part." [BSPO:wd] synonym: "posteroventral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-06-15T01:08:38Z [Term] id: BSPO:0000050 name: antero-medial region namespace: spatial def: "Anatomical region that overlaps the anterior and medial regions of the body or body part." [BSPO:wd] synonym: "anteromedial region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:55:32Z [Term] id: BSPO:0000054 name: anatomical side namespace: spatial def: "An anatomical region bounded by a plane perpendicular to an axis through the middle." [BSPO:cjm] xref: FBql:00005841 is_a: BSPO:0000070 ! anatomical region [Term] id: BSPO:0000055 name: anterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW] synonym: "anterior" EXACT [] synonym: "rostral" EXACT [] xref: FBcv:0000053 xref: FBql:00005848 is_a: BSPO:0000054 ! anatomical side relationship: anterior_to BSPO:0000056 ! posterior side relationship: opposite_to BSPO:0000056 ! posterior side relationship: starts_axis BSPO:0000013 ! anterior-posterior axis [Term] id: BSPO:0000056 name: posterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW, BSPO:wd] synonym: "caudal" NARROW vertebrate [] synonym: "posterior" EXACT [] xref: FBcv:0000065 xref: FBql:00005849 is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000013 ! anterior-posterior axis relationship: posterior_to BSPO:0000055 ! anterior side [Term] id: BSPO:0000061 name: proximal side namespace: spatial synonym: "proximal" EXACT [] xref: FBcv:0000066 xref: FBql:00005852 is_a: BSPO:0000054 ! anatomical side relationship: opposite_to BSPO:0000062 ! distal side relationship: starts_axis BSPO:0000015 ! proximal-distal axis [Term] id: BSPO:0000062 name: distal side namespace: spatial def: "Anatomical side that is distally located on an organism or structure." [BSPO:wd] synonym: "distal" EXACT [] xref: FBcv:0000058 xref: FBql:00005853 is_a: BSPO:0000054 ! anatomical side relationship: distal_to BSPO:0000061 ! proximal side relationship: finishes_axis BSPO:0000015 ! proximal-distal axis [Term] id: BSPO:0000064 name: postero-medial region namespace: spatial def: "Anatomical region that overlaps the posterior and medial regions of the body or body part." [BSPO:wd] synonym: "posteromedial region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:56:39Z [Term] id: BSPO:0000066 name: lateral side namespace: spatial synonym: "lateral" EXACT [] xref: FBcv:0000063 xref: FBql:00005844 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000067 name: medial side namespace: spatial comment: a point in the centre of the organism (where the left-right axis intersects the midsagittal plane) synonym: "medial" EXACT [] xref: FBcv:0000064 xref: FBql:00005847 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000068 name: ventral side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane." [BSPO:RW, BSPO:wd] synonym: "ventral" EXACT [] xref: FBcv:0000070 xref: FBql:00005843 is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000016 ! dorsal-ventral axis [Term] id: BSPO:0000070 name: anatomical region namespace: spatial def: "A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm." [BSPO:cjm] comment: to be merged into CARO xref: FBql:00005841 is_a: CARO:0000003 ! connected anatomical structure [Term] id: BSPO:0000071 name: anterior region namespace: spatial def: "Anatomical region anteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side relationship: overlaps BSPO:0000055 ! anterior side [Term] id: BSPO:0000072 name: posterior region namespace: spatial def: "Anatomical region posteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side relationship: overlaps BSPO:0000056 ! posterior side [Term] id: BSPO:0000077 name: proximal region namespace: spatial def: "Anatomical region proximally located on the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000061 ! proximal side relationship: overlaps BSPO:0000061 ! proximal side [Term] id: BSPO:0000078 name: distal region namespace: spatial def: "Anatomical region distally located on the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000062 ! distal side relationship: overlaps BSPO:0000062 ! distal side [Term] id: BSPO:0000082 name: lateral region namespace: spatial def: "Anatomical region laterally located on the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000066 ! lateral side relationship: overlaps BSPO:0000066 ! lateral side [Term] id: BSPO:0000083 name: medial region namespace: spatial def: "Anatomical region medially located on the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000067 ! medial side relationship: overlaps BSPO:0000067 ! medial side [Term] id: BSPO:0000084 name: ventral region namespace: spatial def: "Anatomical region ventrally located on the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000068 ! ventral side relationship: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000085 name: ventro-lateral region namespace: spatial def: "Anatomical region that overlaps the ventral and lateral regions of a body or body part." [BSPO:wd] comment: This is an example of a composition of two axis positions. synonym: "ventrolateral region" EXACT [] xref: FBql:00005846 is_a: BSPO:0000082 ! lateral region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000066 ! lateral side intersection_of: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000112 name: ventro-medial region namespace: spatial def: "The region corresponding to the ventral region of the entity, towards the midline." [BSPO:wd] synonym: "medioventral region" EXACT [] synonym: "ventromedial region" EXACT [] is_a: BSPO:0000083 ! medial region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000067 ! medial side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-09-10T08:57:54Z [Term] id: BSPO:0000196 name: medial-external axis namespace: spatial def: "An anatomical axis that extends from the center of the body outwards or externally." [BSPO:curators] comment: The medial-external axis could apply to a sphere-shaped body. synonym: "proximal-distal axis" RELATED [] is_a: BSPO:0000010 ! anatomical axis created_by: wasila.dahdul creation_date: 2013-07-02T11:21:42Z [Term] id: BSPO:0000371 name: anterior surface namespace: spatial def: "Anatomical surface that is located on the anterior side of the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000055 ! anterior side relationship: surface_of BSPO:0000055 ! anterior side [Term] id: BSPO:0000372 name: posterior surface namespace: spatial def: "Anatomical surface that is located on the posterior side of the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000056 ! posterior side relationship: surface_of BSPO:0000056 ! posterior side [Term] id: BSPO:0000377 name: proximal surface namespace: spatial def: "Anatomical surface that is located on the proximal side of the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000061 ! proximal side relationship: surface_of BSPO:0000061 ! proximal side [Term] id: BSPO:0000378 name: distal surface namespace: spatial def: "Anatomical surface that is located on the distal side of the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000062 ! distal side relationship: surface_of BSPO:0000062 ! distal side [Term] id: BSPO:0000382 name: lateral surface namespace: spatial def: "Anatomical surface that located on the lateral side of the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000066 ! lateral side relationship: surface_of BSPO:0000066 ! lateral side [Term] id: BSPO:0000383 name: medial surface namespace: spatial def: "Anatomical surface that located on the medial side of the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000067 ! medial side relationship: surface_of BSPO:0000067 ! medial side [Term] id: BSPO:0000384 name: ventral surface namespace: spatial def: "Anatomical surface that is located on the ventral side of the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000068 ! ventral side relationship: surface_of BSPO:0000068 ! ventral side [Term] id: BSPO:0000400 name: anatomical plane namespace: spatial def: "A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions." [BSPO:cjm] comment: These anatomical sections are applicable to most bilaterally symmetrical animals, but bipedal animals such as humans have more complex usage of these terms. For example, in post-embryonic humans a coronal plane is vertical and a transverse plane is horizontal, but for embryos and quadrupeds a coronal plane is horizontal and a transverse plane is vertical. synonym: "anatomical cross-section" EXACT [] synonym: "anatomical section" EXACT [] synonym: "cross-section" RELATED [] synonym: "plane" EXACT [] synonym: "section" EXACT [] xref: FMA:242982 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000417 name: sagittal plane namespace: spatial def: "Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size." [BSPO:cjm, BSPO:DOS, BSPO:mah] synonym: "left/right plane" EXACT [] synonym: "median plane" EXACT [] synonym: "sagittal section" EXACT [] xref: FMA:11361 is_a: BSPO:0000010 ! anatomical axis is_a: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis intersection_of: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis intersection_of: orthogonal_to BSPO:0000017 ! left-right axis relationship: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis relationship: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis relationship: orthogonal_to BSPO:0000017 ! left-right axis [Term] id: BSPO:0001001 name: medial-lateral axis namespace: spatial def: "An axis that extends from the center of organism to one or other side." [BSPO:cjm] comment: Properly, the ML axis is a half axis; practically, its usage is less clumsy and less linguistically biased than "left-right". The terms may still be used relatively to describe locations along the LR axis. The gills are medial to the operculum, but lateral to the heart. synonym: "M-L axis" EXACT [] synonym: "medio-lateral axis" EXACT [] synonym: "mediolateral axis" EXACT [] synonym: "ML axis" EXACT [] synonym: "proximal-distal axis " RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG is_a: BSPO:0000196 ! medial-external axis [Term] id: CARO:0000000 name: anatomical entity namespace: spatial def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [CAROC:Brownsville2014] def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [CARO:MAH] comment: Following BFO, material anatomical entities may have immaterial parts (the lumen of your stomach is part of your stomach). The granularity limit follows the limits set by the Gene Ontology on the granularity limit for GO:cellular_component. Note that substances produced by an organism (sweat, feaces, urine) do not need to be part of an organism to qualify as an anatomical structure. is_a: BFO:0000004 ! independent continuant [Term] id: CARO:0000003 name: anatomical structure name: connected anatomical structure namespace: spatial def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CC:DOS] comment: Note that the definition does not say 'generated exclusively by the co-ordinated expression of the organism's own genome', so this is still valid for cases where normal morphogenesis requires the actions of a facultative symbiont, or some looser dependency such as the a requirement for the presence of gut flora for normal gut development. is_a: CARO:0000006 ! material anatomical entity [Term] id: CARO:0000006 name: material anatomical entity namespace: spatial def: "An anatomical entity that has mass." [CC:DOS] is_a: CARO:0000000 ! anatomical entity disjoint_from: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000007 name: immaterial anatomical entity namespace: spatial def: "An anatomical entity that has no mass." [CC:DOS] def: "Anatomical entity that has no mass." [] is_a: BFO:0000141 ! immaterial entity is_a: CARO:0000000 ! anatomical entity [Term] id: CARO:0000008 name: anatomical line namespace: spatial def: "A one dimensional, immaterial anatomical entity." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000010 name: anatomical boundary namespace: spatial def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CHEBI:10545 name: electron def: "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." [] subset: 3_STAR synonym: "beta" RELATED [IUPAC] synonym: "beta(-)" RELATED [ChEBI] synonym: "beta-particle" RELATED [IUPAC] synonym: "e" RELATED [IUPAC] synonym: "e(-)" RELATED [UniProt] synonym: "e-" RELATED [KEGG_COMPOUND] synonym: "electron" EXACT IUPAC_NAME [ChEBI, IUPAC, KEGG_COMPOUND] synonym: "Elektron" RELATED [ChEBI] synonym: "negatron" RELATED [IUPAC] xref: KEGG:C05359 xref: PMID:21614077 {source="Europe PMC"} xref: Wikipedia:Electron is_a: CHEBI:36338 ! lepton [Term] id: CHEBI:131927 name: dicarboxylic acids and O-substituted derivatives def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." [] subset: 3_STAR synonym: "dicarboxylic acids and derivatives" RELATED [ChEBI] is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:132153 name: hyaluronate def: "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." [] subset: 3_STAR synonym: "hyaluronan" RELATED [UniProt] synonym: "hyaluronate polyanion" RELATED [ChEBI] is_a: CHEBI:61469 ! polyanionic polymer is_a: CHEBI:63551 ! carbohydrate acid derivative anion relationship: is_conjugate_base_of CHEBI:16336 ! hyaluronic acid [Term] id: CHEBI:136889 name: 5beta steroid def: "Any steroid that has beta-configuration at position 5." [] subset: 3_STAR synonym: "5beta steroids" RELATED [ChEBI] synonym: "5beta-steroid" RELATED [ChEBI] synonym: "5beta-steroids" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:138103 name: inorganic acid def: "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." [] subset: 3_STAR synonym: "inorganic acids" RELATED [ChEBI] synonym: "mineral acid" RELATED [ChEBI] synonym: "mineral acids" RELATED [ChEBI] xref: Wikipedia:Mineral_acid is_a: CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:138366 name: bile acids def: "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." [] subset: 3_STAR is_a: CHEBI:25384 ! monocarboxylic acid is_a: CHEBI:35350 ! hydroxy steroid is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:138675 name: gas molecular entity def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." [] subset: 3_STAR synonym: "gas molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entity" RELATED [ChEBI] xref: Wikipedia:https\://en.wikipedia.org/wiki/Gas is_a: CHEBI:33579 ! main group molecular entity [Term] id: CHEBI:13941 name: carbamate subset: 3_STAR synonym: "Carbamat" RELATED [ChEBI] synonym: "carbamate" EXACT IUPAC_NAME [IUPAC, UniProt] synonym: "carbamate ion" RELATED [ChemIDplus] synonym: "carbamic acid, ion(1-)" RELATED [ChemIDplus] synonym: "Karbamat" RELATED [ChEBI] xref: Beilstein:3903503 {source="Beilstein"} xref: CAS:302-11-4 {source="ChemIDplus"} xref: Gmelin:239604 {source="Gmelin"} is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:28616 ! carbamic acid [Term] id: CHEBI:142163 name: 24G7 epitope def: "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." [] subset: 3_STAR is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24433 ! group relationship: RO:0000087 CHEBI:53000 ! has role epitope [Term] id: CHEBI:15339 name: acceptor alt_id: CHEBI:13699 alt_id: CHEBI:2377 def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." [] subset: 3_STAR synonym: "A" RELATED [KEGG_COMPOUND] synonym: "accepteur" RELATED [ChEBI] synonym: "Acceptor" EXACT [KEGG_COMPOUND] synonym: "Akzeptor" RELATED [ChEBI] synonym: "Hydrogen-acceptor" RELATED [KEGG_COMPOUND] synonym: "Oxidized donor" RELATED [KEGG_COMPOUND] xref: KEGG:C00028 xref: KEGG:C16722 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:15355 name: acetylcholine alt_id: CHEBI:12686 alt_id: CHEBI:13715 alt_id: CHEBI:22197 alt_id: CHEBI:2416 alt_id: CHEBI:40559 def: "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." [] subset: 3_STAR synonym: "2-acetyloxy-N,N,N-trimethylethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "ACETYLCHOLINE" EXACT [PDBeChem] synonym: "Acetylcholine" EXACT [KEGG_COMPOUND] synonym: "acetylcholine" EXACT [UniProt] synonym: "ACh" RELATED [ChemIDplus] synonym: "Azetylcholin" RELATED [ChEBI] synonym: "choline acetate" RELATED [ChemIDplus] synonym: "O-Acetylcholine" RELATED [KEGG_COMPOUND] xref: Beilstein:1764436 {source="ChemIDplus"} xref: CAS:51-84-3 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Drug_Central:65 {source="DrugCentral"} xref: DrugBank:DB03128 xref: Gmelin:326108 {source="Gmelin"} xref: KEGG:C01996 xref: LINCS:LSM-5888 xref: PDBeChem:ACH xref: PMID:14764638 {source="Europe PMC"} xref: PMID:15014918 {source="Europe PMC"} xref: PMID:15231705 {source="Europe PMC"} xref: PMID:15361288 {source="Europe PMC"} xref: PMID:18050502 {source="Europe PMC"} xref: PMID:18407448 {source="Europe PMC"} xref: PMID:19255787 {source="Europe PMC"} xref: PMID:20963497 {source="Europe PMC"} xref: PMID:21130809 {source="Europe PMC"} xref: PMID:21246223 {source="Europe PMC"} xref: PMID:21545631 {source="Europe PMC"} xref: PMID:21601579 {source="Europe PMC"} xref: Wikipedia:Acetylcholine is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35287 ! acylcholine is_a: CHEBI:47622 ! acetate ester relationship: RO:0000087 CHEBI:24621 ! has role hormone relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent relationship: RO:0000087 CHEBI:38325 ! has role muscarinic agonist relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:15366 name: acetic acid alt_id: CHEBI:22169 alt_id: CHEBI:2387 alt_id: CHEBI:40486 def: "A simple monocarboxylic acid containing two carbons." [] subset: 3_STAR synonym: "ACETIC ACID" EXACT [PDBeChem] synonym: "Acetic acid" EXACT [KEGG_COMPOUND] synonym: "acetic acid" EXACT IUPAC_NAME [IUPAC] synonym: "acide acetique" RELATED [ChemIDplus] synonym: "AcOH" RELATED [ChEBI] synonym: "CH3-COOH" RELATED [IUPAC] synonym: "CH3CO2H" RELATED [ChEBI] synonym: "E 260" RELATED [ChEBI] synonym: "E-260" RELATED [ChEBI] synonym: "E260" RELATED [ChEBI] synonym: "Essigsaeure" RELATED [ChEBI] synonym: "Ethanoic acid" RELATED [KEGG_COMPOUND] synonym: "ethoic acid" RELATED [ChEBI] synonym: "Ethylic acid" RELATED [ChemIDplus] synonym: "HOAc" RELATED [ChEBI] synonym: "INS No. 260" RELATED [ChEBI] synonym: "MeCO2H" RELATED [ChEBI] synonym: "MeCOOH" RELATED [ChEBI] synonym: "Methanecarboxylic acid" RELATED [ChemIDplus] xref: CAS:64-19-7 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Drug_Central:4211 {source="DrugCentral"} xref: Gmelin:1380 {source="Gmelin"} xref: HMDB:HMDB0000042 xref: KEGG:C00033 xref: KEGG:D00010 xref: KNApSAcK:C00001176 xref: LIPID_MAPS_instance:LMFA01010002 {source="LIPID MAPS"} xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PDBeChem:ACY xref: PMID:12005138 {source="Europe PMC"} xref: PMID:15107950 {source="Europe PMC"} xref: PMID:16630552 {source="Europe PMC"} xref: PMID:16774200 {source="Europe PMC"} xref: PMID:17190852 {source="Europe PMC"} xref: PMID:19416101 {source="Europe PMC"} xref: PMID:19469536 {source="Europe PMC"} xref: PMID:22153255 {source="Europe PMC"} xref: PMID:22173419 {source="Europe PMC"} xref: PPDB:1333 xref: Reaxys:506007 {source="Reaxys"} xref: Wikipedia:Acetic_acid is_a: CHEBI:25384 ! monocarboxylic acid relationship: is_conjugate_acid_of CHEBI:30089 ! acetate relationship: RO:0000087 CHEBI:48356 ! has role protic solvent relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite [Term] id: CHEBI:15377 name: water alt_id: CHEBI:10743 alt_id: CHEBI:13352 alt_id: CHEBI:27313 alt_id: CHEBI:42043 alt_id: CHEBI:42857 alt_id: CHEBI:43228 alt_id: CHEBI:44292 alt_id: CHEBI:44701 alt_id: CHEBI:44819 alt_id: CHEBI:5585 def: "An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms" [] subset: 3_STAR synonym: "[OH2]" RELATED [IUPAC] synonym: "acqua" RELATED [ChEBI] synonym: "agua" RELATED [ChEBI] synonym: "aqua" RELATED [ChEBI] synonym: "BOUND WATER" RELATED [PDBeChem] synonym: "dihydridooxygen" RELATED [IUPAC] synonym: "dihydrogen oxide" RELATED [IUPAC] synonym: "eau" RELATED [ChEBI] synonym: "H2O" RELATED [KEGG_COMPOUND, UniProt] synonym: "HOH" RELATED [ChEBI] synonym: "hydrogen hydroxide" RELATED [ChEBI] synonym: "oxidane" EXACT IUPAC_NAME [IUPAC] synonym: "Wasser" RELATED [ChEBI] synonym: "WATER" EXACT [PDBeChem] synonym: "Water" EXACT [KEGG_COMPOUND] synonym: "water" EXACT IUPAC_NAME [IUPAC] xref: CAS:7732-18-5 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Gmelin:117 {source="Gmelin"} xref: HMDB:HMDB0002111 xref: KEGG:C00001 xref: KEGG:D00001 xref: MetaCyc:WATER xref: MolBase:1 xref: PDBeChem:HOH xref: Reaxys:3587155 {source="Reaxys"} xref: Wikipedia:Water is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33693 ! oxygen hydride is_a: CHEBI:37176 ! mononuclear parent hydride is_a: CHEBI:52625 ! inorganic hydroxy compound relationship: is_conjugate_acid_of CHEBI:16234 ! hydroxide relationship: is_conjugate_base_of CHEBI:29412 ! oxonium relationship: RO:0000087 CHEBI:48360 ! has role amphiprotic solvent relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:15379 name: dioxygen alt_id: CHEBI:10745 alt_id: CHEBI:13416 alt_id: CHEBI:23833 alt_id: CHEBI:25366 alt_id: CHEBI:30491 alt_id: CHEBI:44742 alt_id: CHEBI:7860 subset: 3_STAR synonym: "[OO]" RELATED [MolBase] synonym: "dioxygen" EXACT IUPAC_NAME [IUPAC] synonym: "dioxygene" RELATED [ChEBI] synonym: "Disauerstoff" RELATED [ChEBI] synonym: "E 948" RELATED [ChEBI] synonym: "E-948" RELATED [ChEBI] synonym: "E948" RELATED [ChEBI] synonym: "molecular oxygen" RELATED [ChEBI] synonym: "O2" RELATED [IUPAC, KEGG_COMPOUND, UniProt] synonym: "Oxygen" RELATED [KEGG_COMPOUND] synonym: "OXYGEN MOLECULE" RELATED [PDBeChem] xref: CAS:7782-44-7 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Gmelin:485 {source="Gmelin"} xref: HMDB:HMDB0001377 xref: KEGG:C00007 xref: KEGG:D00003 xref: MetaCyc:OXYGEN-MOLECULE xref: MolBase:750 xref: PDBeChem:OXY xref: PMID:10906528 {source="Europe PMC"} xref: PMID:16977326 {source="Europe PMC"} xref: PMID:18210929 {source="Europe PMC"} xref: PMID:18638417 {source="Europe PMC"} xref: PMID:19840863 {source="Europe PMC"} xref: PMID:7710549 {source="Europe PMC"} xref: PMID:9463773 {source="Europe PMC"} xref: Wikipedia:Oxygen is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:25362 ! elemental molecule is_a: CHEBI:33263 ! diatomic oxygen relationship: is_conjugate_base_of CHEBI:29793 ! hydridodioxygen(1+) relationship: RO:0000087 CHEBI:27027 ! has role micronutrient relationship: RO:0000087 CHEBI:33893 ! has role reagent relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas [Term] id: CHEBI:15693 name: aldose alt_id: CHEBI:13755 alt_id: CHEBI:22305 alt_id: CHEBI:2561 def: "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." [] subset: 3_STAR synonym: "Aldose" EXACT [KEGG_COMPOUND] synonym: "aldoses" RELATED [ChEBI] synonym: "an aldose" RELATED [UniProt] xref: KEGG:C01370 xref: Wikipedia:Aldose is_a: CHEBI:35381 ! monosaccharide [Term] id: CHEBI:15841 name: polypeptide alt_id: CHEBI:14860 alt_id: CHEBI:8314 def: "A peptide containing ten or more amino acid residues." [] subset: 3_STAR synonym: "polipeptido" RELATED [ChEBI] synonym: "Polypeptid" RELATED [ChEBI] synonym: "Polypeptide" EXACT [KEGG_COMPOUND] synonym: "polypeptides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00403 is_a: CHEBI:16670 ! peptide [Term] id: CHEBI:15986 name: polynucleotide alt_id: CHEBI:13672 alt_id: CHEBI:14859 alt_id: CHEBI:8312 def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." [] subset: 3_STAR synonym: "Polynucleotide" EXACT [KEGG_COMPOUND] synonym: "polynucleotides" RELATED [ChEBI] xref: KEGG:C00419 is_a: CHEBI:33695 ! information biomacromolecule is_a: CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_part CHEBI:50319 ! nucleotide residue [Term] id: CHEBI:16134 name: ammonia alt_id: CHEBI:13405 alt_id: CHEBI:13406 alt_id: CHEBI:13407 alt_id: CHEBI:13771 alt_id: CHEBI:22533 alt_id: CHEBI:44269 alt_id: CHEBI:44284 alt_id: CHEBI:44404 alt_id: CHEBI:7434 def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." [] subset: 3_STAR synonym: "[NH3]" RELATED [MolBase] synonym: "AMMONIA" EXACT [PDBeChem] synonym: "Ammonia" EXACT [KEGG_COMPOUND] synonym: "ammonia" EXACT IUPAC_NAME [IUPAC] synonym: "ammoniac" RELATED [ChEBI] synonym: "Ammoniak" RELATED [ChemIDplus] synonym: "amoniaco" RELATED [ChEBI] synonym: "azane" EXACT IUPAC_NAME [IUPAC] synonym: "NH3" RELATED [IUPAC, KEGG_COMPOUND] synonym: "R-717" RELATED [ChEBI] synonym: "spirit of hartshorn" RELATED [ChemIDplus] xref: CAS:7664-41-7 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Drug_Central:4625 {source="DrugCentral"} xref: Gmelin:79 {source="Gmelin"} xref: HMDB:HMDB0000051 xref: KEGG:C00014 xref: KEGG:D02916 xref: KNApSAcK:C00007267 xref: MetaCyc:AMMONIA xref: MolBase:930 xref: PDBeChem:NH3 xref: PMID:110589 {source="Europe PMC"} xref: PMID:11139349 {source="Europe PMC"} xref: PMID:11540049 {source="Europe PMC"} xref: PMID:11746427 {source="Europe PMC"} xref: PMID:11783653 {source="Europe PMC"} xref: PMID:13753780 {source="Europe PMC"} xref: PMID:14663195 {source="Europe PMC"} xref: PMID:15092448 {source="Europe PMC"} xref: PMID:15094021 {source="Europe PMC"} xref: PMID:15554424 {source="Europe PMC"} xref: PMID:15969015 {source="Europe PMC"} xref: PMID:16008360 {source="Europe PMC"} xref: PMID:16050680 {source="Europe PMC"} xref: PMID:16348008 {source="Europe PMC"} xref: PMID:16349403 {source="Europe PMC"} xref: PMID:16614889 {source="Europe PMC"} xref: PMID:16664306 {source="Europe PMC"} xref: PMID:16842901 {source="Europe PMC"} xref: PMID:17025297 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17569513 {source="Europe PMC"} xref: PMID:17737668 {source="Europe PMC"} xref: PMID:18670398 {source="Europe PMC"} xref: PMID:22002069 {source="Europe PMC"} xref: PMID:22081570 {source="Europe PMC"} xref: PMID:22088435 {source="Europe PMC"} xref: PMID:22100291 {source="Europe PMC"} xref: PMID:22130175 {source="Europe PMC"} xref: PMID:22150211 {source="Europe PMC"} xref: PMID:22240068 {source="Europe PMC"} xref: PMID:22290316 {source="Europe PMC"} xref: PMID:22342082 {source="Europe PMC"} xref: PMID:22385337 {source="Europe PMC"} xref: PMID:22443779 {source="Europe PMC"} xref: PMID:22560242 {source="Europe PMC"} xref: Reaxys:3587154 {source="Reaxys"} xref: Wikipedia:Ammonia is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:35107 ! azane is_a: CHEBI:37176 ! mononuclear parent hydride relationship: is_conjugate_acid_of CHEBI:29337 ! azanide relationship: is_conjugate_base_of CHEBI:28938 ! ammonium relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin relationship: RO:0000087 CHEBI:59740 ! has role nucleophilic reagent relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor relationship: RO:0000087 CHEBI:78433 ! has role refrigerant [Term] id: CHEBI:16189 name: sulfate alt_id: CHEBI:15135 alt_id: CHEBI:45687 alt_id: CHEBI:9335 def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." [] subset: 3_STAR synonym: "[SO4](2-)" RELATED [IUPAC] synonym: "SO4(2-)" RELATED [IUPAC] synonym: "Sulfate" EXACT [KEGG_COMPOUND] synonym: "sulfate" EXACT IUPAC_NAME [IUPAC, UniProt] synonym: "Sulfate anion(2-)" RELATED [HMDB] synonym: "Sulfate dianion" RELATED [HMDB] synonym: "SULFATE ION" RELATED [PDBeChem] synonym: "Sulfate(2-)" RELATED [HMDB] synonym: "Sulfuric acid ion(2-)" RELATED [HMDB] synonym: "sulphate" RELATED [ChEBI] synonym: "sulphate ion" RELATED [ChEBI] synonym: "tetraoxidosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] xref: CAS:14808-79-8 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:2120 {source="Gmelin"} xref: HMDB:HMDB0001448 xref: KEGG:C00059 xref: KEGG:D05963 xref: MetaCyc:SULFATE xref: PDBeChem:SO4 xref: PMID:11200094 {source="Europe PMC"} xref: PMID:11452993 {source="Europe PMC"} xref: PMID:11581495 {source="Europe PMC"} xref: PMID:11798107 {source="Europe PMC"} xref: PMID:12166931 {source="Europe PMC"} xref: PMID:12668033 {source="Europe PMC"} xref: PMID:14597181 {source="Europe PMC"} xref: PMID:15093386 {source="Europe PMC"} xref: PMID:15984785 {source="Europe PMC"} xref: PMID:16186560 {source="Europe PMC"} xref: PMID:16345535 {source="Europe PMC"} xref: PMID:16347366 {source="Europe PMC"} xref: PMID:16348007 {source="Europe PMC"} xref: PMID:16483812 {source="Europe PMC"} xref: PMID:16534979 {source="Europe PMC"} xref: PMID:16656509 {source="Europe PMC"} xref: PMID:16742508 {source="Europe PMC"} xref: PMID:16742518 {source="Europe PMC"} xref: PMID:17120760 {source="Europe PMC"} xref: PMID:17420092 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17709180 {source="Europe PMC"} xref: PMID:18398178 {source="Europe PMC"} xref: PMID:18815700 {source="Europe PMC"} xref: PMID:18846414 {source="Europe PMC"} xref: PMID:19047345 {source="Europe PMC"} xref: PMID:19244483 {source="Europe PMC"} xref: PMID:19544990 {source="Europe PMC"} xref: PMID:19628332 {source="Europe PMC"} xref: PMID:19812358 {source="Europe PMC"} xref: PMID:30398859 {source="Europe PMC"} xref: Reaxys:3648446 {source="Reaxys"} xref: Wikipedia:Sulfate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33482 ! sulfur oxoanion is_a: CHEBI:48154 ! sulfur oxide is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:45696 ! hydrogensulfate relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:16234 name: hydroxide alt_id: CHEBI:13365 alt_id: CHEBI:13419 alt_id: CHEBI:44641 alt_id: CHEBI:5594 subset: 3_STAR synonym: "HO-" RELATED [KEGG_COMPOUND] synonym: "hydridooxygenate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxide" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROXIDE ION" RELATED [PDBeChem] synonym: "Hydroxide ion" RELATED [KEGG_COMPOUND] synonym: "OH(-)" RELATED [IUPAC] synonym: "OH-" RELATED [KEGG_COMPOUND] synonym: "oxidanide" EXACT IUPAC_NAME [IUPAC] xref: CAS:14280-30-9 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:24714 {source="Gmelin"} xref: KEGG:C01328 xref: PDBeChem:OH is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33693 ! oxygen hydride relationship: is_conjugate_base_of CHEBI:15377 ! water relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite [Term] id: CHEBI:16336 name: hyaluronic acid alt_id: CHEBI:14412 alt_id: CHEBI:24622 alt_id: CHEBI:24623 alt_id: CHEBI:5772 def: "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." [] subset: 3_STAR synonym: "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n" RELATED [ChEBI] synonym: "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n" RELATED [KEGG_COMPOUND] synonym: "acide hyaluronique" RELATED [ChEBI] synonym: "acido hialuronico" RELATED [ChEBI] synonym: "hyaluronan" RELATED [ChEBI] synonym: "Hyaluronic acid" EXACT [KEGG_COMPOUND] synonym: "Hyaluronsaeure" RELATED [ChEBI] xref: Beilstein:8538277 {source="Beilstein"} xref: CAS:9004-61-9 {source="ChemIDplus", source="KEGG COMPOUND"} xref: HMDB:HMDB0010366 xref: KEGG:C00518 xref: KEGG:D08043 xref: KEGG:G10505 xref: PMID:11122186 {source="Europe PMC"} xref: PMID:18056362 {source="Europe PMC"} xref: PMID:18290544 {source="Europe PMC"} xref: Reaxys:8187837 {source="Reaxys"} xref: Wikipedia:Hyaluronan is_a: CHEBI:37395 ! mucopolysaccharide is_a: CHEBI:72813 ! exopolysaccharide relationship: is_conjugate_acid_of CHEBI:132153 ! hyaluronate relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:16541 name: protein polypeptide chain alt_id: CHEBI:8526 def: "A naturally occurring polypeptide synthesized at the ribosome." [] subset: 3_STAR synonym: "a protein" RELATED [UniProt] synonym: "polypeptide chain" RELATED [ChEBI] synonym: "Protein" RELATED [KEGG_COMPOUND] synonym: "protein polypeptide chains" RELATED [ChEBI] xref: KEGG:C00017 is_a: CHEBI:15841 ! polypeptide relationship: has_part CHEBI:33700 ! proteinogenic amino-acid residue [Term] id: CHEBI:16646 name: carbohydrate alt_id: CHEBI:15131 alt_id: CHEBI:23008 alt_id: CHEBI:9318 def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." [] subset: 3_STAR synonym: "a carbohydrate" RELATED [UniProt] synonym: "carbohidrato" RELATED [IUPAC] synonym: "carbohidratos" RELATED [IUPAC] synonym: "carbohydrate" EXACT IUPAC_NAME [IUPAC] synonym: "carbohydrates" EXACT IUPAC_NAME [IUPAC] synonym: "glucide" RELATED [ChEBI] synonym: "glucides" RELATED [ChEBI] synonym: "glucido" RELATED [ChEBI] synonym: "glucidos" RELATED [ChEBI] synonym: "hydrates de carbone" RELATED [ChEBI] synonym: "Kohlenhydrat" RELATED [ChEBI] synonym: "Kohlenhydrate" RELATED [ChEBI] synonym: "saccharide" RELATED [IUPAC] synonym: "saccharides" RELATED [IUPAC] synonym: "saccharidum" RELATED [ChEBI] xref: Wikipedia:Carbohydrate is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16670 name: peptide alt_id: CHEBI:14753 alt_id: CHEBI:25906 alt_id: CHEBI:7990 def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." [] def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from α-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." [] subset: 3_STAR synonym: "Peptid" RELATED [ChEBI] synonym: "Peptide" EXACT [KEGG_COMPOUND] synonym: "peptides" EXACT IUPAC_NAME [IUPAC] synonym: "peptido" RELATED [ChEBI] synonym: "peptidos" RELATED [ChEBI] xref: KEGG:C00012 is_a: CHEBI:33839 ! macromolecule is_a: CHEBI:37622 ! carboxamide is_a: CHEBI:50047 ! organic amino compound relationship: has_part CHEBI:33708 ! amino-acid residue relationship: is_tautomer_of CHEBI:60466 ! peptide zwitterion property_value: IAO:0000111 "peptide" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/chebi.owl [Term] id: CHEBI:166902 name: noradrenaline(1+) subset: 2_STAR synonym: "noradrenaline" RELATED [UniProt] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:33569 ! noradrenaline [Term] id: CHEBI:167559 name: glycan def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." [] subset: 3_STAR synonym: "glycans" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16765 name: tryptamine alt_id: CHEBI:15274 alt_id: CHEBI:27161 alt_id: CHEBI:46157 alt_id: CHEBI:9767 def: "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." [] subset: 3_STAR synonym: "1H-indole-3-ethanamine" RELATED [NIST_Chemistry_WebBook] synonym: "2-(1H-INDOL-3-YL)ETHANAMINE" RELATED [PDBeChem] synonym: "2-(1H-indol-3-yl)ethanamine" EXACT IUPAC_NAME [IUPAC] synonym: "2-(3-indolyl)ethylamine" RELATED [ChemIDplus] synonym: "3-(2-Aminoethyl)indole" RELATED [KEGG_COMPOUND] synonym: "Tryptamine" EXACT [KEGG_COMPOUND] xref: CAS:61-54-1 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: DrugBank:DB08653 xref: Gmelin:603448 {source="Gmelin"} xref: HMDB:HMDB0000303 xref: KEGG:C00398 xref: KNApSAcK:C00001434 xref: MetaCyc:TRYPTAMINE xref: PDBeChem:TSS xref: PMID:16126914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24345948 {source="Europe PMC"} xref: PMID:24558969 {source="Europe PMC"} xref: Reaxys:125513 {source="Reaxys"} xref: Wikipedia:Tryptamine is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:38631 ! aminoalkylindole is_a: CHEBI:38958 ! indole alkaloid is_a: CHEBI:64365 ! aralkylamino compound relationship: is_conjugate_base_of CHEBI:57887 ! tryptaminium relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:16990 name: bilirubin IXalpha alt_id: CHEBI:13898 alt_id: CHEBI:22870 alt_id: CHEBI:3099 def: "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." [] subset: 3_STAR synonym: "1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid" RELATED [ChemIDplus] synonym: "2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid" RELATED [ChemIDplus] synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" RELATED [IUPAC] synonym: "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione" RELATED [JCBN] synonym: "Bilirubin" RELATED [KEGG_COMPOUND] synonym: "bilirubin" EXACT IUPAC_NAME [IUPAC] synonym: "bilirubin(Z,Z)" RELATED [ChEBI] synonym: "bilirubin-IXalpha" RELATED [ChEBI] xref: CAS:635-65-4 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:411033 {source="Gmelin"} xref: HMDB:HMDB0000054 xref: KEGG:C00486 xref: KNApSAcK:C00029828 xref: MetaCyc:BILIRUBIN xref: PDBeChem:BLR xref: PMID:12799017 {source="Europe PMC"} xref: PMID:18442622 {source="Europe PMC"} xref: PMID:23763371 {source="Europe PMC"} xref: PMID:23768684 {source="Europe PMC"} xref: PMID:30224965 {source="Europe PMC"} xref: PMID:8605219 {source="Europe PMC"} xref: PMID:9587403 {source="Europe PMC"} xref: Reaxys:74376 {source="Reaxys"} xref: Wikipedia:Bilirubin is_a: CHEBI:35692 ! dicarboxylic acid is_a: CHEBI:36735 ! biladienes relationship: has_part CHEBI:142163 ! 24G7 epitope relationship: is_conjugate_acid_of CHEBI:57977 ! bilirubin(2-) relationship: RO:0000087 CHEBI:22586 ! has role antioxidant relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:17087 name: ketone alt_id: CHEBI:13427 alt_id: CHEBI:13646 alt_id: CHEBI:24974 alt_id: CHEBI:6127 alt_id: CHEBI:8742 def: "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." [] subset: 3_STAR synonym: "a ketone" RELATED [UniProt] synonym: "cetone" RELATED [ChEBI] synonym: "Keton" RELATED [ChEBI] synonym: "Ketone" EXACT [KEGG_COMPOUND] synonym: "ketones" EXACT IUPAC_NAME [IUPAC] synonym: "ketones" RELATED [ChEBI] synonym: "R-CO-R'" RELATED [KEGG_COMPOUND] xref: KEGG:C01450 xref: Wikipedia:Ketone is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:17089 name: glycoprotein alt_id: CHEBI:14349 alt_id: CHEBI:5481 alt_id: CHEBI:5493 def: "A compound in which a carbohydrate component is covalently bound to a protein component." [] subset: 3_STAR synonym: "a glycoprotein" RELATED [UniProt] synonym: "glicoproteina" RELATED [ChEBI] synonym: "glicoproteinas" RELATED [ChEBI] synonym: "Glycoprotein" EXACT [KEGG_COMPOUND] synonym: "glycoproteine" RELATED [ChEBI] synonym: "glycoproteines" RELATED [ChEBI] synonym: "glycoproteins" EXACT IUPAC_NAME [IUPAC] synonym: "Glykoprotein" RELATED [ChEBI] synonym: "Glykoproteine" RELATED [ChEBI] xref: KEGG:C00326 is_a: CHEBI:33837 ! conjugated protein is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:17234 name: glucose alt_id: CHEBI:14313 alt_id: CHEBI:24277 alt_id: CHEBI:33929 alt_id: CHEBI:5418 def: "An aldohexose used as a source of energy and metabolic intermediate." [] subset: 3_STAR synonym: "DL-glucose" RELATED [ChEBI] synonym: "Glc" RELATED [JCBN] synonym: "gluco-hexose" EXACT IUPAC_NAME [IUPAC] synonym: "Glucose" EXACT [KEGG_COMPOUND] synonym: "glucose" EXACT IUPAC_NAME [IUPAC] synonym: "Glukose" RELATED [ChEBI] xref: CAS:50-99-7 {source="KEGG COMPOUND"} xref: KEGG:C00293 xref: Wikipedia:Glucose is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33917 ! aldohexose relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite [Term] id: CHEBI:17544 name: hydrogencarbonate alt_id: CHEBI:13363 alt_id: CHEBI:22863 alt_id: CHEBI:40961 alt_id: CHEBI:5589 def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." [] subset: 3_STAR synonym: "[CO2(OH)](-)" RELATED [IUPAC] synonym: "Acid carbonate" RELATED [KEGG_COMPOUND] synonym: "Bicarbonate" RELATED [KEGG_COMPOUND] synonym: "BICARBONATE ION" RELATED [PDBeChem] synonym: "HCO3(-)" RELATED [IUPAC] synonym: "HCO3-" RELATED [KEGG_COMPOUND] synonym: "hydrogen carbonate" RELATED [PDBeChem] synonym: "hydrogen(trioxidocarbonate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND] synonym: "hydrogencarbonate" EXACT IUPAC_NAME [IUPAC, UniProt] synonym: "hydrogencarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(IV)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidodioxidocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3903504 {source="Beilstein"} xref: CAS:71-52-3 {source="ChemIDplus"} xref: Gmelin:49249 {source="Gmelin"} xref: HMDB:HMDB0000595 xref: KEGG:C00288 xref: MetaCyc:HCO3 xref: PDBeChem:BCT xref: PMID:17215880 {source="Europe PMC"} xref: PMID:17505962 {source="Europe PMC"} xref: PMID:18439416 {source="Europe PMC"} xref: PMID:28732801 {source="Europe PMC"} xref: PMID:29150416 {source="Europe PMC"} xref: PMID:29460248 {source="Europe PMC"} xref: PMID:29466234 {source="Europe PMC"} xref: PMID:4208463 {source="Europe PMC"} xref: Wikipedia:Bicarbonate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35604 ! carbon oxoanion relationship: is_conjugate_acid_of CHEBI:41609 ! carbonate relationship: is_conjugate_base_of CHEBI:28976 ! carbonic acid relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:17608 name: D-aldohexose alt_id: CHEBI:12990 alt_id: CHEBI:21038 def: "Any D-aldose having a chain of six carbon atoms in the molecule." [] subset: 3_STAR synonym: "D-aldohexoses" RELATED [ChEBI] is_a: CHEBI:33917 ! aldohexose is_a: CHEBI:4194 ! D-hexose [Term] id: CHEBI:17634 name: D-glucose alt_id: CHEBI:12965 alt_id: CHEBI:20999 def: "A glucose with D-configuration." [] subset: 3_STAR synonym: "D(+)-glucose" RELATED [ChemIDplus] synonym: "D-(+)-glucose" RELATED [NIST_Chemistry_WebBook] synonym: "D-gluco-hexose" EXACT IUPAC_NAME [IUPAC] synonym: "D-glucose" EXACT IUPAC_NAME [IUPAC] synonym: "dextrose" RELATED [NIST_Chemistry_WebBook] synonym: "grape sugar" RELATED [ChemIDplus] synonym: "Traubenzucker" RELATED [ChemIDplus] xref: CAS:50-99-7 {source="ChemIDplus", source="NIST Chemistry WebBook"} is_a: CHEBI:17234 ! glucose is_a: CHEBI:17608 ! D-aldohexose [Term] id: CHEBI:17843 name: transfer RNA alt_id: CHEBI:10652 alt_id: CHEBI:15145 alt_id: CHEBI:15163 alt_id: CHEBI:15164 alt_id: CHEBI:15165 def: "A single-stranded RNA molecule containing about 70-90 nucleotides, folded by intrastrand base pairing into a characteristic secondary ('cloverleaf') structure that carries a specific amino acid and matches it to its corresponding codon on an mRNA during protein synthesis." [] subset: 3_STAR synonym: "RNA, transfer" RELATED [ChemIDplus] synonym: "transfer RNA" EXACT IUPAC_NAME [IUPAC, KEGG_COMPOUND] synonym: "tRNA" RELATED [KEGG_COMPOUND, UniProt] xref: CAS:9014-25-9 {source="ChemIDplus"} xref: KEGG:C00066 is_a: CHEBI:33697 ! ribonucleic acid [Term] id: CHEBI:17891 name: donor alt_id: CHEBI:14202 alt_id: CHEBI:4697 def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." [] subset: 3_STAR synonym: "Donator" RELATED [ChEBI] synonym: "donneur" RELATED [ChEBI] synonym: "Donor" EXACT [KEGG_COMPOUND] xref: KEGG:C01351 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:18059 name: lipid alt_id: CHEBI:14517 alt_id: CHEBI:25054 alt_id: CHEBI:6486 def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." [] subset: 3_STAR synonym: "Lipid" EXACT [KEGG_COMPOUND] synonym: "lipids" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C01356 is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:18085 name: glycosaminoglycan alt_id: CHEBI:14361 alt_id: CHEBI:24398 alt_id: CHEBI:5495 def: "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." [] subset: 3_STAR synonym: "glicosaminoglicano" RELATED [IUPAC] synonym: "Glycosaminoglycan" EXACT [KEGG_COMPOUND] synonym: "glycosaminoglycan" EXACT IUPAC_NAME [IUPAC] synonym: "glycosaminoglycane" RELATED [IUPAC] synonym: "glycosaminoglycans" RELATED [ChEBI] synonym: "Glykosaminoglykan" RELATED [ChEBI] xref: KEGG:C02545 xref: Wikipedia:Glycosaminoglycan is_a: CHEBI:22506 ! aminoglycan [Term] id: CHEBI:18133 name: hexose alt_id: CHEBI:14399 alt_id: CHEBI:24590 alt_id: CHEBI:5709 def: "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." [] subset: 3_STAR synonym: "Hexose" EXACT [KEGG_COMPOUND] synonym: "hexoses" RELATED [ChEBI] synonym: "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/" RELATED [GlyTouCan] xref: GlyGen:G70994MS xref: GlyTouCan:G70994MS xref: KEGG:C00738 is_a: CHEBI:35381 ! monosaccharide [Term] id: CHEBI:18154 name: polysaccharide alt_id: CHEBI:14864 alt_id: CHEBI:26205 alt_id: CHEBI:8322 def: "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." [] subset: 3_STAR synonym: "Glycan" RELATED [KEGG_COMPOUND] synonym: "Glycane" RELATED [ChEBI] synonym: "glycans" RELATED [IUPAC] synonym: "Glykan" RELATED [ChEBI] synonym: "Glykane" RELATED [ChEBI] synonym: "polisacarido" RELATED [ChEBI] synonym: "polisacaridos" RELATED [IUPAC] synonym: "Polysaccharide" EXACT [KEGG_COMPOUND] synonym: "polysaccharides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00420 is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:18282 name: nucleobase alt_id: CHEBI:13873 alt_id: CHEBI:25598 alt_id: CHEBI:2995 def: "That part of DNA or RNA that may be involved in pairing." [] subset: 3_STAR synonym: "Base" RELATED [KEGG_COMPOUND] synonym: "nucleobases" RELATED [ChEBI] xref: KEGG:C00701 xref: Wikipedia:Nucleobase is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:18357 name: (R)-noradrenaline alt_id: CHEBI:1 alt_id: CHEBI:14668 alt_id: CHEBI:25592 alt_id: CHEBI:258884 alt_id: CHEBI:43725 def: "The R-enantiomer of noradrenaline." [] subset: 3_STAR synonym: "(-)-arterenol" RELATED [ChemIDplus] synonym: "(-)-noradrenaline" RELATED [IUPHAR] synonym: "(-)-norepinephrine" RELATED [ChemIDplus] synonym: "(R)-(-)-norepinephrine" RELATED [ChemIDplus] synonym: "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol" RELATED [ChemIDplus] synonym: "(R)-norepinephrine" RELATED [ChemIDplus] synonym: "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol" RELATED [KEGG_COMPOUND] synonym: "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] synonym: "Arterenol" RELATED [KEGG_COMPOUND] synonym: "L-Noradrenaline" RELATED [KEGG_COMPOUND] synonym: "L-NOREPINEPHRINE" RELATED [PDBeChem] synonym: "Noradrenaline" RELATED [KEGG_COMPOUND] synonym: "norepinefrina" RELATED INN [ChEBI] synonym: "Norepinephrine" RELATED [KEGG_COMPOUND] synonym: "norepinephrine" RELATED INN [ChemIDplus, WHO_MedNet] synonym: "norepinephrinum" RELATED INN [ChEBI] xref: Beilstein:4231961 {source="ChemIDplus"} xref: CAS:51-41-2 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Drug_Central:1960 {source="DrugCentral"} xref: DrugBank:DB00368 xref: HMDB:HMDB0000216 xref: KEGG:C00547 xref: KEGG:D00076 xref: KNApSAcK:C00001424 xref: PDBeChem:LNR xref: Reaxys:2804840 {source="Reaxys"} xref: Wikipedia:Norepinephrine is_a: CHEBI:33569 ! noradrenaline relationship: is_conjugate_base_of CHEBI:72587 ! (R)-noradrenaline(1+) relationship: is_enantiomer_of CHEBI:33571 ! (S)-noradrenaline relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent relationship: RO:0000087 CHEBI:35569 ! has role alpha-adrenergic agonist relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite [Term] id: CHEBI:20664 name: 5beta-cholane subset: 3_STAR synonym: "5beta-cholane" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:2048472 {source="Beilstein"} is_a: CHEBI:35519 ! cholane [Term] id: CHEBI:22221 name: acyl group def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." [] subset: 3_STAR synonym: "acyl group" EXACT [IUPAC] synonym: "acyl groups" RELATED [ChEBI] synonym: "alkanoyl" EXACT IUPAC_NAME [IUPAC] synonym: "alkanoyl group" RELATED [ChEBI] synonym: "groupe acyle" RELATED [IUPAC] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:22314 name: alkali metal atom subset: 3_STAR synonym: "alkali metal" RELATED [ChEBI] synonym: "alkali metals" EXACT IUPAC_NAME [IUPAC] synonym: "Alkalimetall" RELATED [ChEBI] synonym: "Alkalimetalle" RELATED [ChEBI] synonym: "metal alcalin" RELATED [ChEBI] synonym: "metal alcalino" RELATED [ChEBI] synonym: "metales alcalinos" RELATED [ChEBI] synonym: "metaux alcalins" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom is_a: CHEBI:33521 ! metal atom is_a: CHEBI:33559 ! s-block element atom [Term] id: CHEBI:22315 name: alkaloid def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." [] subset: 3_STAR synonym: "alcaloide" RELATED [ChEBI] synonym: "alcaloides" RELATED [ChEBI] synonym: "Alkaloid" EXACT [ChEBI] synonym: "Alkaloide" RELATED [ChEBI] synonym: "alkaloids" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Alkaloid is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35352 ! organonitrogen compound relationship: RO:0000087 CHEBI:25212 ! has role metabolite [Term] id: CHEBI:22506 name: aminoglycan subset: 3_STAR synonym: "aminoglycans" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:65212 ! polysaccharide derivative [Term] id: CHEBI:22563 name: anion def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." [] subset: 3_STAR synonym: "Anion" EXACT [ChEBI] synonym: "anion" EXACT IUPAC_NAME [ChEBI, IUPAC] synonym: "Anionen" RELATED [ChEBI] synonym: "aniones" RELATED [ChEBI] synonym: "anions" RELATED [IUPAC] is_a: CHEBI:24870 ! ion [Term] id: CHEBI:22586 name: antioxidant def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." [] subset: 3_STAR synonym: "antioxidants" RELATED [ChEBI] synonym: "antioxydant" RELATED [ChEBI] synonym: "antoxidant" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22695 name: base def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." [] subset: 3_STAR synonym: "Base" EXACT [ChEBI] synonym: "base" EXACT IUPAC_NAME [ChEBI, IUPAC] synonym: "Base1" RELATED [KEGG_COMPOUND] synonym: "Base2" RELATED [KEGG_COMPOUND] synonym: "Basen" RELATED [ChEBI] synonym: "bases" RELATED [ChEBI] synonym: "Nucleobase" RELATED [KEGG_COMPOUND] xref: KEGG:C00701 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22728 name: benzopyrrole subset: 3_STAR synonym: "benzopyrroles" RELATED [ChEBI] is_a: CHEBI:27171 ! organic heterobicyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound is_a: CHEBI:38180 ! polycyclic heteroarene [Term] id: CHEBI:228364 name: NMR chemical shift reference compound def: "Any compound that produces a peak used as reference frequency in the delta chemical shift scale." [] subset: 3_STAR synonym: "NMR chemical shift reference compounds" RELATED [ChEBI] synonym: "NMR chemical shift standard" RELATED [ChEBI] synonym: "NMR chemical shift standards" RELATED [ChEBI] synonym: "NMR internal standard" RELATED [ChEBI] synonym: "NMR internal standards" RELATED [ChEBI] synonym: "NMR reference standard" RELATED [ChEBI] synonym: "NMR reference standards" RELATED [ChEBI] is_a: CHEBI:33232 ! application is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22868 name: bile salt def: "A sodium salt of the conjugate of any bile acid with either glycine or taurine." [] subset: 3_STAR synonym: "Bile acid" RELATED [KEGG_COMPOUND] synonym: "bile salts" RELATED [ChEBI] xref: KEGG:C01558 is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:38700 ! organic sodium salt [Term] id: CHEBI:23004 name: carbamoyl group def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." [] subset: 3_STAR synonym: "-C(O)NH2" RELATED [ChEBI] synonym: "-CONH2" RELATED [IUPAC] synonym: "aminocarbonyl" RELATED [IUPAC] synonym: "carbamoyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbamyl" RELATED [ChEBI] synonym: "carbamyl group" RELATED [ChEBI] synonym: "carboxamide" RELATED [IUPAC] xref: PMID:24168430 {source="Europe PMC"} is_a: CHEBI:27207 ! univalent carboacyl group relationship: is_substituent_group_from CHEBI:28616 ! carbamic acid [Term] id: CHEBI:23019 name: carbonyl group subset: 3_STAR synonym: ">C=O" RELATED [IUPAC] synonym: "carbonyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbonyl group" EXACT [ChEBI, UniProt] is_a: CHEBI:51422 ! organodiyl group [Term] id: CHEBI:23357 name: cofactor def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." [] subset: 3_STAR synonym: "cofactor" EXACT [IUPAC] synonym: "cofactors" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Cofactor_(biochemistry) is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:23367 name: molecular entity def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." [] subset: 3_STAR synonym: "entidad molecular" RELATED [IUPAC] synonym: "entidades moleculares" RELATED [IUPAC] synonym: "entite moleculaire" RELATED [IUPAC] synonym: "molecular entities" RELATED [IUPAC] synonym: "molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "molekulare Entitaet" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:23449 name: cyclic peptide subset: 3_STAR synonym: "cyclic peptides" RELATED [ChEBI] synonym: "Cyclopeptid" RELATED [ChEBI] synonym: "peptide cyclique" RELATED [IUPAC] synonym: "peptido ciclico" RELATED [IUPAC] synonym: "Zyklopeptid" RELATED [ChEBI] is_a: CHEBI:16670 ! peptide [Term] id: CHEBI:23888 name: drug def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." [] subset: 3_STAR synonym: "drugs" RELATED [ChEBI] synonym: "medicine" RELATED [ChEBI] is_a: CHEBI:52217 ! pharmaceutical [Term] id: CHEBI:23906 name: monoatomic cation subset: 3_STAR synonym: "monoatomic cations" RELATED [ChEBI] is_a: CHEBI:24867 ! monoatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:23924 name: enzyme inhibitor def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." [] subset: 3_STAR synonym: "enzyme inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "enzyme inhibitors" RELATED [ChEBI] synonym: "inhibidor enzimatico" RELATED [ChEBI] synonym: "inhibidores enzimaticos" RELATED [ChEBI] synonym: "inhibiteur enzymatique" RELATED [ChEBI] synonym: "inhibiteurs enzymatiques" RELATED [ChEBI] is_a: CHEBI:35222 ! inhibitor is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:24384 name: glycogens subset: 3_STAR is_a: CHEBI:37163 ! glucan [Term] id: CHEBI:24431 name: chemical entity def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." [] subset: 3_STAR synonym: "chemical entity" EXACT [UniProt] [Term] id: CHEBI:24432 name: biological role def: "A role played by the molecular entity or part thereof within a biological context." [] subset: 3_STAR synonym: "biological function" RELATED [ChEBI] is_a: CHEBI:50906 ! role [Term] id: CHEBI:24433 name: group def: "A defined linked collection of atoms or a single atom within a molecular entity." [] subset: 3_STAR synonym: "group" EXACT IUPAC_NAME [IUPAC] synonym: "groupe" RELATED [IUPAC] synonym: "grupo" RELATED [IUPAC] synonym: "grupos" RELATED [IUPAC] synonym: "Gruppe" RELATED [ChEBI] synonym: "Rest" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity relationship: has_part CHEBI:33250 ! atom [Term] id: CHEBI:24532 name: organic heterocyclic compound def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." [] subset: 3_STAR synonym: "organic heterocycle" RELATED [ChEBI] synonym: "organic heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33832 ! organic cyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:24533 name: heterodetic cyclic peptide def: "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." [] subset: 3_STAR synonym: "heterodetic cyclic peptide" EXACT IUPAC_NAME [IUPAC] synonym: "heterodetic cyclic peptides" RELATED [ChEBI] synonym: "peptide cyclique heterodetique" RELATED [IUPAC] synonym: "peptido ciclico heterodetico" RELATED [IUPAC] is_a: CHEBI:23449 ! cyclic peptide [Term] id: CHEBI:24621 name: hormone def: "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." [] subset: 3_STAR synonym: "endocrine" RELATED [ChEBI] synonym: "hormones" RELATED [ChEBI] is_a: CHEBI:33280 ! molecular messenger is_a: CHEBI:48705 ! agonist [Term] id: CHEBI:24636 name: proton def: "Nuclear particle of charge number +1, spin 1/2 and rest mass of 1.007276470(12) u." [] def: "Nuclear particle of charge number +1, spin ½ and rest mass of 1.007276470(12) u." [] is_a: CHEBI:36342 ! subatomic particle is_a: COB:0000013 ! molecule property_value: IAO:0000111 "proton" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/chebi.owl [Term] id: CHEBI:24651 name: hydroxides def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." [] subset: 3_STAR is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:43176 ! hydroxy group [Term] id: CHEBI:24663 name: hydroxy-5beta-cholanic acid def: "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." [] subset: 3_STAR synonym: "hydroxy-5beta-cholanic acids" RELATED [ChEBI] is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:36248 ! 5beta-cholanic acids relationship: has_functional_parent CHEBI:36238 ! 5beta-cholanic acid [Term] id: CHEBI:24828 name: indoles def: "Any compound containing an indole skeleton." [] subset: 3_STAR is_a: CHEBI:22728 ! benzopyrrole [Term] id: CHEBI:24833 name: oxoacid def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [] subset: 3_STAR synonym: "oxacids" RELATED [ChEBI] synonym: "oxiacids" RELATED [ChEBI] synonym: "oxo acid" RELATED [ChEBI] synonym: "oxoacid" EXACT IUPAC_NAME [IUPAC] synonym: "oxoacids" EXACT IUPAC_NAME [IUPAC] synonym: "oxy-acids" RELATED [ChEBI] synonym: "oxyacids" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24651 ! hydroxides relationship: RO:0000087 CHEBI:39141 ! has role Bronsted acid [Term] id: CHEBI:24834 name: inorganic anion subset: 3_STAR synonym: "inorganic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36914 ! inorganic ion [Term] id: CHEBI:24835 name: inorganic molecular entity def: "A molecular entity that contains no carbon." [] subset: 3_STAR synonym: "anorganische Verbindungen" RELATED [ChEBI] synonym: "inorganic compounds" RELATED [ChEBI] synonym: "inorganic entity" RELATED [ChEBI] synonym: "inorganic molecular entities" RELATED [ChEBI] synonym: "inorganics" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:24836 name: inorganic oxide subset: 3_STAR synonym: "inorganic oxides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25741 ! oxide [Term] id: CHEBI:24866 name: salt def: "A salt is an assembly of cations and anions." [] subset: 3_STAR synonym: "ionic compound" RELATED [ChEBI] synonym: "ionic compounds" RELATED [ChEBI] synonym: "sal" RELATED [ChEBI] synonym: "sales" RELATED [ChEBI] synonym: "salt" EXACT IUPAC_NAME [IUPAC] synonym: "salts" RELATED [ChEBI] synonym: "Salz" RELATED [ChEBI] synonym: "Salze" RELATED [ChEBI] synonym: "sel" RELATED [ChEBI] synonym: "sels" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:22563 ! anion relationship: has_part CHEBI:36916 ! cation [Term] id: CHEBI:24867 name: monoatomic ion subset: 3_STAR synonym: "monoatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:33238 ! monoatomic entity [Term] id: CHEBI:24868 name: organic salt subset: 3_STAR synonym: "organic salts" RELATED [ChEBI] synonym: "organisches Salz" RELATED [ChEBI] is_a: CHEBI:24866 ! salt [Term] id: CHEBI:24870 name: ion def: "A molecular entity having a net electric charge." [] subset: 3_STAR synonym: "Ion" EXACT [ChEBI] synonym: "ion" EXACT IUPAC_NAME [ChEBI, IUPAC] synonym: "Ionen" RELATED [ChEBI] synonym: "iones" RELATED [ChEBI] synonym: "ions" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:25046 name: linear tetrapyrrole subset: 1_STAR is_a: CHEBI:26932 ! tetrapyrrole [Term] id: CHEBI:25212 name: metabolite alt_id: CHEBI:26619 alt_id: CHEBI:35220 def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." [] subset: 3_STAR synonym: "metabolite" EXACT IUPAC_NAME [IUPAC] synonym: "metabolites" RELATED [ChEBI] synonym: "primary metabolites" RELATED [ChEBI] synonym: "secondary metabolites" RELATED [ChEBI] is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:25213 name: metal cation subset: 3_STAR synonym: "a metal cation" RELATED [UniProt] synonym: "metal cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:25362 name: elemental molecule def: "A molecule all atoms of which have the same atomic number." [] subset: 3_STAR synonym: "homoatomic molecule" RELATED [ChEBI] synonym: "homoatomic molecules" RELATED [ChEBI] is_a: CHEBI:25367 ! molecule is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:25367 name: molecule def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." [] subset: 3_STAR synonym: "molecula" RELATED [IUPAC] synonym: "molecule" EXACT [IUPAC] synonym: "molecules" RELATED [IUPAC] synonym: "Molekuel" RELATED [ChEBI] synonym: "neutral molecular compounds" RELATED [IUPAC] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:25375 name: monoamine molecular messenger def: "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [] subset: 3_STAR synonym: "monamines" RELATED [ChEBI] synonym: "monoamines" RELATED [ChEBI] is_a: CHEBI:63534 ! monoamine relationship: RO:0000087 CHEBI:33280 ! has role molecular messenger [Term] id: CHEBI:25384 name: monocarboxylic acid def: "An oxoacid containing a single carboxy group." [] subset: 3_STAR synonym: "monocarboxylic acids" RELATED [ChEBI] is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35757 ! monocarboxylic acid anion [Term] id: CHEBI:25414 name: monoatomic monocation subset: 3_STAR synonym: "monoatomic monocations" RELATED [ChEBI] synonym: "monovalent inorganic cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation [Term] id: CHEBI:25512 name: neurotransmitter def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." [] subset: 3_STAR synonym: "neurotransmitters" RELATED [ChEBI] xref: Wikipedia:Neurotransmitter is_a: CHEBI:33280 ! molecular messenger [Term] id: CHEBI:25555 name: nitrogen atom subset: 3_STAR synonym: "7N" RELATED [IUPAC] synonym: "azote" RELATED [IUPAC] synonym: "N" RELATED [IUPAC] synonym: "nitrogen" EXACT IUPAC_NAME [IUPAC] synonym: "nitrogen" RELATED [ChEBI] synonym: "nitrogeno" RELATED [ChEBI] synonym: "Stickstoff" RELATED [ChEBI] xref: WebElements:N is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:25585 name: nonmetal atom subset: 3_STAR synonym: "Nichtmetall" RELATED [ChEBI] synonym: "Nichtmetalle" RELATED [ChEBI] synonym: "no metal" RELATED [ChEBI] synonym: "no metales" RELATED [ChEBI] synonym: "non-metal" RELATED [ChEBI] synonym: "non-metaux" RELATED [ChEBI] synonym: "nonmetal" EXACT IUPAC_NAME [IUPAC] synonym: "nonmetal" RELATED [ChEBI] synonym: "nonmetals" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:25696 name: organic anion def: "Any organic ion with a net negative charge." [] subset: 3_STAR synonym: "organic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:25699 ! organic ion [Term] id: CHEBI:25697 name: organic cation def: "Any organic ion with a net positive charge." [] subset: 3_STAR synonym: "organic cations" RELATED [ChEBI] is_a: CHEBI:25699 ! organic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:25699 name: organic ion subset: 3_STAR synonym: "organic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:25704 name: organic sulfate def: "Compounds of the general formula SO3HOR where R is an organyl group" [] subset: 3_STAR synonym: "organic sulfates" RELATED [ChEBI] is_a: CHEBI:26820 ! sulfates relationship: is_conjugate_acid_of CHEBI:58958 ! organosulfate oxoanion [Term] id: CHEBI:25741 name: oxide def: "An oxide is a chemical compound of oxygen with other chemical elements." [] subset: 3_STAR synonym: "oxide" EXACT [ChEBI] synonym: "oxides" RELATED [ChEBI] is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:25805 name: oxygen atom subset: 3_STAR synonym: "8O" RELATED [IUPAC] synonym: "O" RELATED [IUPAC] synonym: "oxigeno" RELATED [ChEBI] synonym: "oxygen" EXACT IUPAC_NAME [IUPAC] synonym: "oxygen" RELATED [ChEBI] synonym: "oxygene" RELATED [ChEBI] synonym: "Sauerstoff" RELATED [ChEBI] xref: KEGG:C00007 xref: WebElements:O is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:25806 name: oxygen molecular entity subset: 3_STAR synonym: "oxygen molecular entities" RELATED [ChEBI] synonym: "oxygen molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:25805 ! oxygen atom [Term] id: CHEBI:25905 name: peptide hormone def: "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." [] subset: 3_STAR synonym: "peptide hormones" RELATED [ChEBI] synonym: "polypeptide hormone" RELATED [ChEBI] is_a: CHEBI:16670 ! peptide relationship: RO:0000087 CHEBI:24621 ! has role hormone [Term] id: CHEBI:26708 name: sodium atom subset: 3_STAR synonym: "11Na" RELATED [IUPAC] synonym: "Na" RELATED [IUPAC] synonym: "Natrium" RELATED [ChemIDplus] synonym: "natrium" RELATED [IUPAC] synonym: "sodio" RELATED [ChemIDplus] synonym: "sodium" EXACT IUPAC_NAME [IUPAC] synonym: "sodium" RELATED [ChEBI] xref: CAS:7440-23-5 {source="ChemIDplus"} xref: Gmelin:16221 {source="Gmelin"} xref: KEGG:C01330 xref: WebElements:Na is_a: BFO:0000004 ! independent continuant is_a: CHEBI:22314 ! alkali metal atom relationship: RO:0000087 CHEBI:33937 ! has role macronutrient relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite [Term] id: CHEBI:26712 name: sodium molecular entity subset: 3_STAR synonym: "sodium compounds" RELATED [ChEBI] synonym: "sodium molecular entities" RELATED [ChEBI] is_a: CHEBI:33296 ! alkali metal molecular entity relationship: has_part CHEBI:26708 ! sodium atom [Term] id: CHEBI:26714 name: sodium salt def: "Any alkali metal salt having sodium(1+) as the cation." [] subset: 3_STAR synonym: "Natriumsalz" RELATED [ChEBI] synonym: "Natriumsalze" RELATED [ChEBI] synonym: "sodium salts" RELATED [ChEBI] is_a: CHEBI:26712 ! sodium molecular entity is_a: CHEBI:35479 ! alkali metal salt relationship: has_part CHEBI:29101 ! sodium(1+) [Term] id: CHEBI:26764 name: steroid hormone def: "Any steroid that acts as hormone." [] subset: 3_STAR synonym: "hormona esteroide" RELATED [ChEBI] synonym: "hormonas esteroideas" RELATED [ChEBI] synonym: "hormone steroide" RELATED [ChEBI] synonym: "hormones steroides" RELATED [ChEBI] synonym: "steroid hormones" RELATED [ChEBI] synonym: "Steroidhormon" RELATED [ChEBI] synonym: "Steroidhormone" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35341 ! steroid relationship: RO:0000087 CHEBI:24621 ! has role hormone [Term] id: CHEBI:26819 name: sulfuric ester def: "An ester of an alcohol and sulfuric acid." [] subset: 3_STAR synonym: "sulfate ester" RELATED [ChEBI] synonym: "sulfuric acid ester" RELATED [ChEBI] synonym: "sulfuric acid esters" RELATED [ChEBI] is_a: CHEBI:35701 ! ester is_a: CHEBI:37826 ! sulfuric acid derivative [Term] id: CHEBI:26820 name: sulfates def: "Salts and esters of sulfuric acid" [] subset: 3_STAR synonym: "sulfates" EXACT [ChEBI] synonym: "sulfuric acid derivative" RELATED [ChEBI] synonym: "sulphates" RELATED [ChEBI] is_a: CHEBI:37826 ! sulfuric acid derivative [Term] id: CHEBI:26833 name: sulfur atom subset: 3_STAR synonym: "16S" RELATED [IUPAC] synonym: "azufre" RELATED [ChEBI] synonym: "Elemental sulfur" RELATED [KEGG_COMPOUND] synonym: "S" RELATED [IUPAC, KEGG_COMPOUND] synonym: "Schwefel" RELATED [ChEBI] synonym: "soufre" RELATED [ChEBI] synonym: "sulfur" EXACT IUPAC_NAME [IUPAC] synonym: "sulfur" RELATED [ChEBI, UniProt] synonym: "sulphur" RELATED [ChEBI] synonym: "theion" RELATED [IUPAC] xref: CAS:7704-34-9 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: KEGG:C00087 xref: KEGG:D06527 xref: PPDB:605 xref: WebElements:S is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:26835 name: sulfur molecular entity subset: 3_STAR synonym: "sulfur molecular entities" RELATED [ChEBI] synonym: "sulfur molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:26833 ! sulfur atom [Term] id: CHEBI:26836 name: sulfuric acid def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." [] subset: 3_STAR synonym: "[S(OH)2O2]" RELATED [MolBase] synonym: "[SO2(OH)2]" RELATED [IUPAC] synonym: "Acide sulfurique" RELATED [ChemIDplus] synonym: "Acido sulfurico" RELATED [ChemIDplus] synonym: "Acidum sulfuricum" RELATED [ChemIDplus] synonym: "dihydrogen tetraoxosulfate" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidodioxidosulfur" EXACT IUPAC_NAME [IUPAC] synonym: "H2SO4" RELATED [IUPAC] synonym: "hydrogen tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "Schwefelsaeureloesungen" RELATED [ChemIDplus] synonym: "Sulfuric acid" EXACT [KEGG_COMPOUND] synonym: "sulfuric acid" EXACT IUPAC_NAME [ChEBI, IUPAC] synonym: "sulphuric acid" RELATED [MolBase] synonym: "tetraoxosulfuric acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:7664-93-9 {source="ChemIDplus", source="KEGG COMPOUND", source="NIST Chemistry WebBook"} xref: Gmelin:2122 {source="Gmelin"} xref: KEGG:C00059 xref: KEGG:D05963 xref: KNApSAcK:C00007530 xref: MolBase:4 xref: PMID:13568755 {source="Europe PMC"} xref: PMID:16122922 {source="Europe PMC"} xref: PMID:19397353 {source="Europe PMC"} xref: PMID:22047659 {source="Europe PMC"} xref: PMID:22136045 {source="Europe PMC"} xref: PMID:22204399 {source="Europe PMC"} xref: PMID:22267186 {source="Europe PMC"} xref: PMID:22296037 {source="Europe PMC"} xref: PMID:22364556 {source="Europe PMC"} xref: PMID:22435616 {source="Europe PMC"} xref: PPDB:606 xref: Reaxys:2037554 {source="Reaxys"} xref: Wikipedia:Sulfuric_acid is_a: CHEBI:33402 ! sulfur oxoacid relationship: is_conjugate_acid_of CHEBI:45696 ! hydrogensulfate relationship: RO:0000087 CHEBI:35223 ! has role catalyst [Term] id: CHEBI:26932 name: tetrapyrrole def: "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [] subset: 3_STAR synonym: "a tetrapyrrole" RELATED [UniProt] synonym: "tetrapyrrole" EXACT IUPAC_NAME [IUPAC] synonym: "tetrapyrroles" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:38077 ! polypyrrole [Term] id: CHEBI:27027 name: micronutrient def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." [] subset: 3_STAR synonym: "micronutrients" RELATED [ChEBI] synonym: "trace elements" RELATED [ChEBI] xref: Wikipedia:Micronutrient is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:27162 name: tryptamines def: "Tryptamine and its substitution derivatives." [] subset: 3_STAR is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:27171 name: organic heterobicyclic compound subset: 3_STAR synonym: "heterobicyclic compounds" RELATED [ChEBI] synonym: "organic heterobicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33672 ! heterobicyclic compound is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:27207 name: univalent carboacyl group def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "univalent acyl group" RELATED [ChEBI] synonym: "univalent carboacyl groups" RELATED [ChEBI] synonym: "univalent carboxylic acyl groups" RELATED [ChEBI] is_a: CHEBI:37838 ! carboacyl group [Term] id: CHEBI:27369 name: zwitterion def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." [] subset: 3_STAR synonym: "compose zwitterionique" RELATED [IUPAC] synonym: "compuestos zwitterionicos" RELATED [IUPAC] synonym: "zwitterion" EXACT IUPAC_NAME [IUPAC] synonym: "zwitteriones" RELATED [IUPAC] synonym: "zwitterionic compounds" RELATED [IUPAC] synonym: "zwitterions" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51151 ! dipolar compound [Term] id: CHEBI:27594 name: carbon atom alt_id: CHEBI:23009 alt_id: CHEBI:3399 subset: 3_STAR synonym: "6C" RELATED [IUPAC] synonym: "C" RELATED [IUPAC, KEGG_COMPOUND] synonym: "Carbon" RELATED [KEGG_COMPOUND] synonym: "carbon" EXACT IUPAC_NAME [IUPAC] synonym: "carbon" RELATED [ChEBI] synonym: "carbone" RELATED [ChEBI] synonym: "carbonium" RELATED [ChEBI] synonym: "carbono" RELATED [ChEBI] synonym: "Kohlenstoff" RELATED [ChEBI] xref: CAS:7440-44-0 {source="ChemIDplus", source="KEGG COMPOUND"} xref: KEGG:C06265 xref: WebElements:C is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33306 ! carbon group element atom relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:28087 name: glycogen alt_id: CHEBI:24379 alt_id: CHEBI:5466 def: "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." [] subset: 3_STAR synonym: "animal starch" RELATED [ChemIDplus] synonym: "Glycogen" EXACT [KEGG_COMPOUND] synonym: "liver starch" RELATED [ChemIDplus] synonym: "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1" RELATED [GlyTouCan] xref: CAS:9005-79-2 {source="ChemIDplus", source="KEGG COMPOUND"} xref: GlyGen:G99991IU xref: GlyTouCan:G99991IU xref: HMDB:HMDB0000757 xref: KEGG:C00182 xref: MetaCyc:CPD0-971 xref: Wikipedia:Glycogen is_a: CHEBI:24384 ! glycogens relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite [Term] id: CHEBI:28616 name: carbamic acid alt_id: CHEBI:22504 alt_id: CHEBI:23002 alt_id: CHEBI:3386 alt_id: CHEBI:44573 def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." [] subset: 3_STAR synonym: "Aminoameisensaeure" RELATED [ChEBI] synonym: "Aminoformic acid" RELATED [KEGG_COMPOUND] synonym: "Carbamate" RELATED [KEGG_COMPOUND] synonym: "CARBAMIC ACID" EXACT [PDBeChem] synonym: "Carbamic acid" EXACT [KEGG_COMPOUND] synonym: "carbamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Carbamidsaeure" RELATED [ChEBI] xref: Beilstein:1734754 {source="Beilstein"} xref: CAS:463-77-4 {source="ChemIDplus", source="KEGG COMPOUND"} xref: DrugBank:DB04261 xref: Gmelin:130345 {source="Gmelin"} xref: KEGG:C01563 xref: PDBeChem:OUT xref: Wikipedia:Carbamic_acid is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:64708 ! one-carbon compound relationship: is_conjugate_acid_of CHEBI:13941 ! carbamate relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite [Term] id: CHEBI:28790 name: serotonin alt_id: CHEBI:1420 alt_id: CHEBI:26652 alt_id: CHEBI:49894 def: "A primary amino compound that is the 5-hydroxy derivative of tryptamine." [] subset: 3_STAR synonym: "3-(2-Aminoethyl)-1H-indol-5-ol" RELATED [KEGG_COMPOUND] synonym: "3-(2-aminoethyl)-1H-indol-5-ol" EXACT IUPAC_NAME [IUPAC] synonym: "5-HT" RELATED [IUPHAR] synonym: "5-Hydroxytryptamine" RELATED [KEGG_COMPOUND] synonym: "Enteramine" RELATED [KEGG_COMPOUND] synonym: "SEROTONIN" EXACT [PDBeChem] synonym: "Serotonin" EXACT [KEGG_COMPOUND] synonym: "serotonine" RELATED [ChEBI] synonym: "thrombocytin" RELATED [ChemIDplus] synonym: "thrombotonin" RELATED [ChemIDplus] xref: CAS:50-67-9 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:1861995 {source="Gmelin"} xref: HMDB:HMDB0000259 xref: KEGG:C00780 xref: KNApSAcK:C00001429 xref: LINCS:LSM-6589 xref: MetaCyc:SEROTONIN xref: PDBeChem:SRO xref: PMID:18593914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24136337 {source="Europe PMC"} xref: Reaxys:143524 {source="Reaxys"} xref: Wikipedia:Serotonin is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:33853 ! phenols is_a: CHEBI:50994 ! primary amino compound is_a: CHEBI:84729 ! hydroxyindoles relationship: has_functional_parent CHEBI:16765 ! tryptamine relationship: is_conjugate_base_of CHEBI:350546 ! serotonin(1+) relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:28938 name: ammonium alt_id: CHEBI:22534 alt_id: CHEBI:49783 alt_id: CHEBI:7435 def: "An onium cation obtained by protonation of ammonia." [] subset: 3_STAR synonym: "[NH4](+)" RELATED [MolBase] synonym: "ammonium" EXACT IUPAC_NAME [ChEBI, IUPAC] synonym: "ammonium cation" RELATED [ChemIDplus] synonym: "ammonium ion" RELATED [PDBeChem] synonym: "Ammonium(1+)" RELATED [ChemIDplus] synonym: "azanium" EXACT IUPAC_NAME [IUPAC] synonym: "NH4(+)" RELATED [IUPAC, UniProt] synonym: "NH4+" RELATED [KEGG_COMPOUND] xref: CAS:14798-03-9 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:84 {source="Gmelin"} xref: KEGG:C01342 xref: MetaCyc:AMMONIUM xref: MolBase:929 xref: PDBeChem:NH4 xref: PMID:11319011 {source="Europe PMC"} xref: PMID:11341317 {source="Europe PMC"} xref: PMID:12096804 {source="Europe PMC"} xref: PMID:14512268 {source="Europe PMC"} xref: PMID:14879753 {source="Europe PMC"} xref: PMID:16345391 {source="Europe PMC"} xref: PMID:16903292 {source="Europe PMC"} xref: PMID:17392693 {source="Europe PMC"} xref: PMID:18515490 {source="Europe PMC"} xref: PMID:19199063 {source="Europe PMC"} xref: PMID:19596600 {source="Europe PMC"} xref: PMID:19682559 {source="Europe PMC"} xref: PMID:19716251 {source="Europe PMC"} xref: PMID:21993530 {source="Europe PMC"} xref: PMID:22265469 {source="Europe PMC"} xref: PMID:22524020 {source="Europe PMC"} xref: PMID:22562341 {source="Europe PMC"} xref: PMID:22631217 {source="Europe PMC"} xref: Reaxys:16093784 {source="Reaxys"} xref: Wikipedia:Ammonium is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:50313 ! onium cation is_a: CHEBI:60242 ! monovalent inorganic cation relationship: is_conjugate_acid_of CHEBI:16134 ! ammonia relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:28965 name: dicarboxylic acid dianion alt_id: CHEBI:13632 alt_id: CHEBI:23688 alt_id: CHEBI:23689 alt_id: CHEBI:38711 def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." [] subset: 3_STAR synonym: "a dicarboxylate" RELATED [UniProt] synonym: "dicarboxylate" RELATED [ChEBI] synonym: "dicarboxylates" RELATED [ChEBI] synonym: "dicarboxylic acid dianion" EXACT [ChEBI] synonym: "dicarboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:35693 ! dicarboxylic acid anion is_a: CHEBI:38716 ! carboxylic acid dianion [Term] id: CHEBI:28976 name: carbonic acid alt_id: CHEBI:13351 alt_id: CHEBI:23017 alt_id: CHEBI:23744 alt_id: CHEBI:3401 subset: 3_STAR synonym: "[CO(OH)2]" RELATED [IUPAC] synonym: "Carbonic acid" EXACT [KEGG_COMPOUND] synonym: "carbonic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Dihydrogen carbonate" RELATED [KEGG_COMPOUND] synonym: "dihydroxidooxidocarbon" EXACT IUPAC_NAME [IUPAC] synonym: "H2CO3" RELATED [IUPAC, KEGG_COMPOUND] synonym: "Koehlensaeure" RELATED [ChEBI] xref: CAS:463-79-6 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Gmelin:25554 {source="Gmelin"} xref: KEGG:C01353 xref: PDBeChem:CO3 is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36961 ! chalcocarbonic acid relationship: is_conjugate_acid_of CHEBI:17544 ! hydrogencarbonate relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite [Term] id: CHEBI:29067 name: carboxylic acid anion alt_id: CHEBI:13626 alt_id: CHEBI:13945 alt_id: CHEBI:23026 alt_id: CHEBI:58657 def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a carboxylate" RELATED [UniProt] synonym: "carboxylic acid anions" RELATED [ChEBI] synonym: "carboxylic anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion relationship: is_conjugate_base_of CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:29101 name: sodium(1+) alt_id: CHEBI:26717 alt_id: CHEBI:49766 alt_id: CHEBI:9175 def: "A monoatomic monocation obtained from sodium." [] subset: 3_STAR synonym: "Na(+)" RELATED [IUPAC, UniProt] synonym: "Na+" RELATED [KEGG_COMPOUND] synonym: "sodium cation" EXACT IUPAC_NAME [IUPAC] synonym: "SODIUM ION" RELATED [PDBeChem] synonym: "sodium(1+)" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(1+) ion" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(I) cation" EXACT IUPAC_NAME [IUPAC] xref: CAS:17341-25-2 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:15196 {source="Gmelin"} xref: KEGG:C01330 xref: PDBeChem:NA is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25414 ! monoatomic monocation is_a: CHEBI:33504 ! alkali metal cation is_a: CHEBI:37246 ! elemental sodium is_a: CHEBI:60242 ! monovalent inorganic cation relationship: RO:0000087 CHEBI:23357 ! has role cofactor relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:29337 name: azanide subset: 3_STAR synonym: "amide" EXACT IUPAC_NAME [IUPAC] synonym: "azanide" EXACT IUPAC_NAME [IUPAC] synonym: "dihydridonitrate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "NH2(-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:29340 ! hydridonitrate(2-) relationship: is_conjugate_base_of CHEBI:16134 ! ammonia [Term] id: CHEBI:29340 name: hydridonitrate(2-) def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." [] subset: 3_STAR synonym: "azanediide" EXACT IUPAC_NAME [IUPAC] synonym: "hydridonitrate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "imide" RELATED [IUPAC] synonym: "NH(2-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:29337 ! azanide [Term] id: CHEBI:29412 name: oxonium subset: 3_STAR synonym: "[OH3](+)" RELATED [MolBase] synonym: "aquahydrogen(1+)" EXACT IUPAC_NAME [IUPAC] synonym: "H3O(+)" RELATED [IUPAC] synonym: "Hydronium cation" RELATED [NIST_Chemistry_WebBook] synonym: "Hydronium ion" RELATED [ChemIDplus] synonym: "oxidanium" EXACT IUPAC_NAME [IUPAC] synonym: "oxonium" EXACT IUPAC_NAME [IUPAC] synonym: "trihydridooxygen(1+)" EXACT IUPAC_NAME [IUPAC] xref: CAS:13968-08-6 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:141 {source="Gmelin"} xref: MolBase:1646 is_a: CHEBI:33693 ! oxygen hydride is_a: CHEBI:50313 ! onium cation relationship: is_conjugate_acid_of CHEBI:15377 ! water [Term] id: CHEBI:29793 name: hydridodioxygen(1+) subset: 3_STAR synonym: "[HO2](+)" RELATED [ChEBI] synonym: "dioxidenium" EXACT IUPAC_NAME [IUPAC] synonym: "HO2(+)" RELATED [IUPAC] synonym: "HOO(+)" RELATED [ChEBI] synonym: "hydridodioxygen(1+)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:508 {source="Gmelin"} is_a: CHEBI:33693 ! oxygen hydride relationship: is_conjugate_acid_of CHEBI:15379 ! dioxygen [Term] id: CHEBI:30089 name: acetate alt_id: CHEBI:13704 alt_id: CHEBI:22165 alt_id: CHEBI:40480 def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." [] subset: 3_STAR synonym: "acetate" EXACT IUPAC_NAME [IUPAC, UniProt] synonym: "ACETATE ION" RELATED [PDBeChem] synonym: "acetic acid, ion(1-)" RELATED [ChemIDplus] synonym: "Azetat" RELATED [ChEBI] synonym: "CH3-COO(-)" RELATED [IUPAC] synonym: "Ethanoat" RELATED [ChEBI] synonym: "ethanoate" RELATED [ChEBI] synonym: "MeCO2 anion" RELATED [NIST_Chemistry_WebBook] xref: CAS:71-50-1 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: DrugBank:DB03166 xref: Gmelin:1379 {source="Gmelin"} xref: KEGG:C00033 xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PMID:17190852 {source="Europe PMC"} xref: PMID:22211106 {source="Europe PMC"} xref: PMID:22371380 {source="Europe PMC"} xref: Reaxys:1901470 {source="Reaxys"} xref: UM-BBD_compID:c0050 {source="UM-BBD"} xref: Wikipedia:Acetate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35757 ! monocarboxylic acid anion relationship: is_conjugate_base_of CHEBI:15366 ! acetic acid relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:30212 name: photon alt_id: CHEBI:10581 alt_id: CHEBI:14383 def: "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." [] subset: 3_STAR synonym: "foton" RELATED [ChEBI] synonym: "gamma" RELATED [IUPAC] synonym: "hnu" RELATED [IUPAC, UniProt] synonym: "Lichtquant" RELATED [ChEBI] synonym: "Light" RELATED [KEGG_COMPOUND] synonym: "light quantum" RELATED [ChEBI] synonym: "photon" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00205 is_a: CHEBI:36341 ! boson [Term] id: CHEBI:3098 name: bile acid def: "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." [] subset: 3_STAR synonym: "5beta-bile acid" RELATED [ChEBI] synonym: "5beta-bile acids" RELATED [ChEBI] synonym: "Bile acid" EXACT [KEGG_COMPOUND] synonym: "bile acids" RELATED [ChEBI] synonym: "Bile salt" RELATED [KEGG_COMPOUND] synonym: "Gallensaeure" RELATED [ChEBI] synonym: "Gallensaeuren" RELATED [ChEBI] xref: KEGG:C01558 is_a: CHEBI:138366 ! bile acids is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid [Term] id: CHEBI:32952 name: amine alt_id: CHEBI:13814 alt_id: CHEBI:22474 alt_id: CHEBI:2641 def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [] subset: 3_STAR synonym: "Amin" RELATED [ChEBI] synonym: "Amine" EXACT [KEGG_COMPOUND] synonym: "amines" EXACT IUPAC_NAME [IUPAC] synonym: "Substituted amine" RELATED [KEGG_COMPOUND] xref: KEGG:C00706 is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:32988 name: amide alt_id: CHEBI:22473 alt_id: CHEBI:2633 def: "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "Amide" EXACT [KEGG_COMPOUND] synonym: "amides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00241 is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:33232 name: application def: "Intended use of the molecular entity or part thereof by humans." [] subset: 3_STAR is_a: CHEBI:50906 ! role [Term] id: CHEBI:33233 name: fundamental particle def: "A particle not known to have substructure." [] subset: 3_STAR synonym: "elementary particle" EXACT IUPAC_NAME [IUPAC] synonym: "elementary particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:33238 name: monoatomic entity def: "A monoatomic entity is a molecular entity consisting of a single atom." [] subset: 3_STAR synonym: "atomic entity" RELATED [ChEBI] synonym: "monoatomic entities" RELATED [ChEBI] is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33241 name: oxoacid derivative subset: 3_STAR synonym: "oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_functional_parent CHEBI:24833 ! oxoacid [Term] id: CHEBI:33242 name: inorganic hydride subset: 3_STAR synonym: "inorganic hydrides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:33245 name: organic fundamental parent def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." [] subset: 3_STAR synonym: "organic fundamental parents" RELATED [ChEBI] synonym: "organic parent hydrides" RELATED [ChEBI] is_a: CHEBI:37175 ! organic hydride is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33246 name: inorganic group def: "Any substituent group which does not contain carbon." [] subset: 3_STAR synonym: "inorganic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group [Term] id: CHEBI:33247 name: organic group def: "Any substituent group or skeleton containing carbon." [] subset: 3_STAR synonym: "organic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group relationship: is_conjugate_acid_of CHEBI:64775 ! organic anionic group relationship: is_conjugate_base_of CHEBI:64769 ! organic cationic group [Term] id: CHEBI:33249 name: organyl group def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." [] subset: 3_STAR synonym: "groupe organyle" RELATED [IUPAC] synonym: "grupo organilo" RELATED [IUPAC] synonym: "grupos organilo" RELATED [IUPAC] synonym: "organyl group" EXACT IUPAC_NAME [IUPAC] synonym: "organyl groups" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51447 ! organic univalent group [Term] id: CHEBI:33250 name: atom alt_id: CHEBI:22671 alt_id: CHEBI:23907 def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." [] subset: 3_STAR synonym: "atom" EXACT IUPAC_NAME [IUPAC] synonym: "atome" RELATED [IUPAC] synonym: "atomo" RELATED [IUPAC] synonym: "atoms" RELATED [ChEBI] synonym: "atomus" RELATED [ChEBI] synonym: "element" RELATED [ChEBI] synonym: "elements" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity relationship: has_part CHEBI:10545 ! electron relationship: has_part CHEBI:33252 ! atomic nucleus [Term] id: CHEBI:33252 name: atomic nucleus def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." [] subset: 3_STAR synonym: "Atomkern" RELATED [ChEBI] synonym: "Kern" RELATED [ChEBI] synonym: "noyau" RELATED [IUPAC] synonym: "noyau atomique" RELATED [ChEBI] synonym: "nuclei" RELATED [ChEBI] synonym: "nucleo" RELATED [IUPAC] synonym: "nucleo atomico" RELATED [ChEBI] synonym: "nucleus" EXACT IUPAC_NAME [IUPAC] synonym: "nucleus atomi" RELATED [ChEBI] is_a: CHEBI:36347 ! nuclear particle relationship: has_part CHEBI:24636 ! proton property_value: editor_note "Some people may be uncomfortable calling every proton an atomic nucleus" xsd:string property_value: editor_note "This is equivalent to CHEBI:33252" xsd:string [Term] id: CHEBI:33253 name: nucleon def: "Heavy nuclear particle: proton or neutron." [] subset: 3_STAR synonym: "nucleon" EXACT IUPAC_NAME [IUPAC] synonym: "nucleons" RELATED [ChEBI] synonym: "Nukleon" RELATED [ChEBI] synonym: "Nukleonen" RELATED [ChEBI] is_a: CHEBI:36339 ! baryon is_a: CHEBI:36347 ! nuclear particle [Term] id: CHEBI:33256 name: primary amide def: "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "primary amide" EXACT [IUPAC] synonym: "primary amides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:32988 ! amide [Term] id: CHEBI:33259 name: elemental molecular entity def: "A molecular entity all atoms of which have the same atomic number." [] subset: 3_STAR synonym: "homoatomic entity" RELATED [ChEBI] synonym: "homoatomic molecular entities" RELATED [ChEBI] synonym: "homoatomic molecular entity" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:33262 name: elemental oxygen subset: 3_STAR is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33263 name: diatomic oxygen subset: 3_STAR is_a: CHEBI:33262 ! elemental oxygen [Term] id: CHEBI:33273 name: polyatomic anion def: "An anion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36358 ! polyatomic ion [Term] id: CHEBI:33280 name: molecular messenger subset: 3_STAR synonym: "chemical messenger" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33281 name: antimicrobial agent alt_id: CHEBI:22582 def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." [] subset: 3_STAR synonym: "antibiotic" RELATED [ChEBI] synonym: "antibiotics" RELATED [ChEBI] synonym: "Antibiotika" RELATED [ChEBI] synonym: "Antibiotikum" RELATED [ChEBI] synonym: "antibiotique" RELATED [IUPAC] synonym: "antimicrobial" RELATED [ChEBI] synonym: "antimicrobial agents" RELATED [ChEBI] synonym: "antimicrobials" RELATED [ChEBI] synonym: "microbicide" RELATED [ChEBI] synonym: "microbicides" RELATED [ChEBI] xref: PMID:12964249 {source="Europe PMC"} xref: PMID:22117953 {source="Europe PMC"} xref: PMID:22439833 {source="Europe PMC"} xref: PMID:22849268 {source="Europe PMC"} xref: PMID:22849276 {source="Europe PMC"} xref: PMID:22958833 {source="Europe PMC"} is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33284 name: nutrient def: "A nutrient is a food component that an organism uses to survive and grow." [] subset: 3_STAR synonym: "nutrients" RELATED [ChEBI] is_a: CHEBI:78295 ! food component [Term] id: CHEBI:33285 name: heteroorganic entity def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." [] subset: 3_STAR synonym: "heteroorganic entities" RELATED [ChEBI] synonym: "organoelement compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33296 name: alkali metal molecular entity def: "A molecular entity containing one or more atoms of an alkali metal." [] subset: 3_STAR synonym: "alkali metal molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:22314 ! alkali metal atom [Term] id: CHEBI:33300 name: pnictogen def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." [] subset: 3_STAR synonym: "group 15 elements" RELATED [ChEBI] synonym: "group V elements" RELATED [ChEBI] synonym: "nitrogenoideos" RELATED [ChEBI] synonym: "nitrogenoides" RELATED [ChEBI] synonym: "pnictogene" RELATED [ChEBI] synonym: "pnictogenes" RELATED [ChEBI] synonym: "pnictogens" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33302 name: pnictogen molecular entity def: "A p-block molecular entity containing any pnictogen." [] subset: 3_STAR synonym: "pnictogen molecular entities" RELATED [ChEBI] synonym: "pnictogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33300 ! pnictogen [Term] id: CHEBI:33303 name: chalcogen def: "Any p-block element belonging to the group 16 family of the periodic table." [] subset: 3_STAR synonym: "anfigeno" RELATED [ChEBI] synonym: "anfigenos" RELATED [ChEBI] synonym: "calcogeno" RELATED [ChEBI] synonym: "calcogenos" RELATED [ChEBI] synonym: "chalcogen" EXACT IUPAC_NAME [IUPAC] synonym: "chalcogene" RELATED [ChEBI] synonym: "chalcogenes" RELATED [ChEBI] synonym: "chalcogens" EXACT IUPAC_NAME [IUPAC] synonym: "Chalkogen" RELATED [ChEBI] synonym: "Chalkogene" RELATED [ChEBI] synonym: "group 16 elements" RELATED [ChEBI] synonym: "group VI elements" RELATED [ChEBI] xref: PMID:17084588 {source="Europe PMC"} is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33304 name: chalcogen molecular entity def: "Any p-block molecular entity containing a chalcogen." [] subset: 3_STAR synonym: "chalcogen compounds" RELATED [ChEBI] synonym: "chalcogen molecular entities" RELATED [ChEBI] synonym: "chalcogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33303 ! chalcogen [Term] id: CHEBI:33306 name: carbon group element atom subset: 3_STAR synonym: "carbon group element" RELATED [ChEBI] synonym: "carbon group elements" RELATED [ChEBI] synonym: "carbonoides" RELATED [ChEBI] synonym: "cristallogene" RELATED [ChEBI] synonym: "cristallogenes" RELATED [ChEBI] synonym: "group 14 elements" EXACT IUPAC_NAME [IUPAC] synonym: "group IV elements" RELATED [ChEBI] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33308 name: carboxylic ester alt_id: CHEBI:13204 alt_id: CHEBI:23028 alt_id: CHEBI:3408 def: "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." [] subset: 3_STAR synonym: "a carboxylic ester" RELATED [UniProt] synonym: "carboxylic acid esters" RELATED [ChEBI] synonym: "Carboxylic ester" EXACT [KEGG_COMPOUND] synonym: "carboxylic esters" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C02391 xref: Wikipedia:Ester is_a: CHEBI:35701 ! ester is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:33318 name: main group element atom def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." [] subset: 3_STAR synonym: "Hauptgruppenelement" RELATED [ChEBI] synonym: "Hauptgruppenelemente" RELATED [ChEBI] synonym: "main group element" RELATED [ChEBI] synonym: "main group elements" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33402 name: sulfur oxoacid subset: 3_STAR synonym: "oxoacids of sulfur" RELATED [ChEBI] synonym: "sulfur oxoacids" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33484 ! chalcogen oxoacid [Term] id: CHEBI:33424 name: sulfur oxoacid derivative subset: 3_STAR synonym: "sulfur oxoacid derivative" EXACT [ChEBI] synonym: "sulfur oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33241 ! oxoacid derivative [Term] id: CHEBI:33482 name: sulfur oxoanion subset: 3_STAR synonym: "oxoanions of sulfur" RELATED [ChEBI] synonym: "sulfur oxoanion" EXACT [ChEBI] synonym: "sulfur oxoanions" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33485 ! chalcogen oxoanion [Term] id: CHEBI:33484 name: chalcogen oxoacid subset: 3_STAR synonym: "chalcogen oxoacid" EXACT [ChEBI] synonym: "chalcogen oxoacids" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid [Term] id: CHEBI:33485 name: chalcogen oxoanion subset: 3_STAR synonym: "chalcogen oxoanion" EXACT [ChEBI] synonym: "chalcogen oxoanions" RELATED [ChEBI] is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33504 name: alkali metal cation subset: 3_STAR synonym: "alkali metal cations" RELATED [ChEBI] is_a: CHEBI:25213 ! metal cation [Term] id: CHEBI:33521 name: metal atom alt_id: CHEBI:25217 alt_id: CHEBI:6788 def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." [] subset: 3_STAR synonym: "elemental metal" RELATED [ChEBI] synonym: "elemental metals" RELATED [ChEBI] synonym: "metal element" RELATED [ChEBI] synonym: "metal elements" RELATED [ChEBI] synonym: "metals" RELATED [ChEBI] xref: KEGG:C00050 xref: PMID:21784043 {source="Europe PMC"} xref: Wikipedia:Metal is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33558 name: alpha-amino-acid anion def: "An amino-acid anion obtained by deprotonation of any alpha-amino acid." [] subset: 3_STAR synonym: "alpha-amino acid anion" RELATED [ChEBI] synonym: "alpha-amino acid anions" RELATED [ChEBI] synonym: "alpha-amino-acid anions" RELATED [ChEBI] is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33559 name: s-block element atom subset: 3_STAR synonym: "s-block element" RELATED [ChEBI] synonym: "s-block elements" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33560 name: p-block element atom def: "Any main group element atom belonging to the p-block of the periodic table." [] subset: 3_STAR synonym: "p-block element" RELATED [ChEBI] synonym: "p-block elements" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom [Term] id: CHEBI:33566 name: catechols alt_id: CHEBI:134187 alt_id: CHEBI:13628 alt_id: CHEBI:18862 def: "Any compound containing an o-diphenol component." [] subset: 3_STAR synonym: "1,2-benzenediols" RELATED [ChEBI] synonym: "a catechol" RELATED [UniProt] synonym: "benzene-1,2-diols" RELATED [ChEBI] xref: KEGG:C15571 is_a: CHEBI:33570 ! benzenediols [Term] id: CHEBI:33567 name: catecholamine alt_id: CHEBI:23056 alt_id: CHEBI:3468 def: "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [] subset: 3_STAR synonym: "Catecholamine" EXACT [KEGG_COMPOUND] synonym: "catecholamines" EXACT IUPAC_NAME [IUPAC] synonym: "catecholamines" RELATED [ChEBI] xref: KEGG:C02012 is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:33566 ! catechols [Term] id: CHEBI:33569 name: noradrenaline def: "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." [] subset: 3_STAR synonym: "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] synonym: "noradrenalina" RELATED [ChEBI] synonym: "norepinephrine" RELATED [ChEBI] xref: Beilstein:2210994 {source="Beilstein"} xref: CAS:138-65-8 {source="ChemIDplus", source="NIST Chemistry WebBook"} xref: Gmelin:863925 {source="Gmelin"} xref: LINCS:LSM-5181 is_a: CHEBI:33567 ! catecholamine relationship: is_conjugate_base_of CHEBI:166902 ! noradrenaline(1+) relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite [Term] id: CHEBI:33570 name: benzenediols alt_id: CHEBI:22705 alt_id: CHEBI:22711 subset: 3_STAR is_a: CHEBI:33853 ! phenols [Term] id: CHEBI:33571 name: (S)-noradrenaline def: "The S-enantiomer of noradrenaline." [] subset: 3_STAR synonym: "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] xref: LINCS:LSM-37072 xref: Reaxys:2937999 {source="Reaxys"} is_a: CHEBI:33569 ! noradrenaline relationship: is_enantiomer_of CHEBI:18357 ! (R)-noradrenaline [Term] id: CHEBI:33575 name: carboxylic acid alt_id: CHEBI:13428 alt_id: CHEBI:13627 alt_id: CHEBI:23027 def: "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." [] subset: 3_STAR synonym: "acide carboxylique" RELATED [IUPAC] synonym: "acides carboxyliques" RELATED [IUPAC] synonym: "acido carboxilico" RELATED [IUPAC] synonym: "acidos carboxilicos" RELATED [IUPAC] synonym: "Carbonsaeure" RELATED [ChEBI] synonym: "Carbonsaeuren" RELATED [ChEBI] synonym: "carboxylic acid" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Karbonsaeure" RELATED [ChEBI] synonym: "RC(=O)OH" RELATED [IUPAC] xref: PMID:17147560 {source="Europe PMC"} xref: PMID:18433345 {source="Europe PMC"} xref: Wikipedia:Carboxylic_acid is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36586 ! carbonyl compound is_a: CHEBI:64709 ! organic acid relationship: has_part CHEBI:46883 ! carboxy group relationship: is_conjugate_acid_of CHEBI:29067 ! carboxylic acid anion [Term] id: CHEBI:33579 name: main group molecular entity def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." [] subset: 3_STAR synonym: "main group compounds" RELATED [ChEBI] synonym: "main group molecular entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:33318 ! main group element atom [Term] id: CHEBI:33582 name: carbon group molecular entity subset: 3_STAR synonym: "carbon group molecular entities" RELATED [ChEBI] synonym: "carbon group molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33306 ! carbon group element atom [Term] id: CHEBI:33595 name: cyclic compound def: "Any molecule that consists of a series of atoms joined together to form a ring." [] subset: 3_STAR synonym: "cyclic compounds" RELATED [ChEBI] xref: Wikipedia:Cyclic_compound is_a: CHEBI:25367 ! molecule [Term] id: CHEBI:33608 name: hydrogen molecular entity subset: 3_STAR synonym: "hydrogen compounds" RELATED [ChEBI] synonym: "hydrogen molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:49637 ! hydrogen atom [Term] id: CHEBI:33635 name: polycyclic compound subset: 3_STAR synonym: "polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33636 name: bicyclic compound def: "A molecule that features two fused rings." [] subset: 3_STAR synonym: "bicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33655 name: aromatic compound def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." [] subset: 3_STAR synonym: "aromatic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "aromatic molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "aromatics" RELATED [ChEBI] synonym: "aromatische Verbindungen" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33659 name: organic aromatic compound subset: 3_STAR synonym: "organic aromatic compounds" RELATED [ChEBI] is_a: CHEBI:33655 ! aromatic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:33671 name: heteropolycyclic compound def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." [] subset: 3_STAR synonym: "heteropolycyclic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "polyheterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33672 name: heterobicyclic compound def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." [] subset: 3_STAR synonym: "heterobicyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33636 ! bicyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33674 name: s-block molecular entity def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." [] subset: 3_STAR synonym: "s-block compounds" RELATED [ChEBI] synonym: "s-block molecular entities" RELATED [ChEBI] synonym: "s-block molecular entity" EXACT [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33559 ! s-block element atom [Term] id: CHEBI:33675 name: p-block molecular entity def: "A main group molecular entity that contains one or more atoms of a p-block element." [] subset: 3_STAR synonym: "p-block compounds" RELATED [ChEBI] synonym: "p-block molecular entities" RELATED [ChEBI] synonym: "p-block molecular entitiy" RELATED [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33692 name: hydrides def: "Hydrides are chemical compounds of hydrogen with other chemical elements." [] subset: 3_STAR is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:33693 name: oxygen hydride subset: 3_STAR synonym: "hydrides of oxygen" RELATED [ChEBI] synonym: "oxygen hydride" EXACT [ChEBI] synonym: "oxygen hydrides" RELATED [ChEBI] is_a: CHEBI:36902 ! chalcogen hydride [Term] id: CHEBI:33694 name: biomacromolecule def: "A macromolecule formed by a living organism." [] subset: 3_STAR synonym: "biomacromolecules" RELATED [ChEBI] synonym: "biopolymer" EXACT IUPAC_NAME [IUPAC] synonym: "Biopolymere" RELATED [ChEBI] synonym: "biopolymers" RELATED [ChEBI] is_a: CHEBI:33839 ! macromolecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33695 name: information biomacromolecule subset: 3_STAR synonym: "genetically encoded biomacromolecules" RELATED [ChEBI] synonym: "genetically encoded biopolymers" RELATED [ChEBI] synonym: "information biomacromolecules" RELATED [ChEBI] synonym: "information biopolymers" RELATED [ChEBI] synonym: "information macromolecule" RELATED [ChEBI] synonym: "information macromolecules" RELATED [ChEBI] is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:33696 name: nucleic acid def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." [] subset: 3_STAR synonym: "acide nucleique" RELATED [ChEBI] synonym: "acides nucleiques" RELATED [ChEBI] synonym: "acido nucleico" RELATED [ChEBI] synonym: "acidos nucleicos" RELATED [ChEBI] synonym: "NA" RELATED [ChEBI] synonym: "nucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Nukleinsaeure" RELATED [ChEBI] synonym: "Nukleinsaeuren" RELATED [ChEBI] is_a: CHEBI:15986 ! polynucleotide relationship: has_part CHEBI:33791 ! canonical nucleoside residue relationship: has_part CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:33697 name: ribonucleic acid def: "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." [] subset: 3_STAR synonym: "pentosenucleic acids" RELATED [ChemIDplus] synonym: "ribonucleic acid" EXACT [IUPAC] synonym: "ribonucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "ribonucleic acids" RELATED [ChEBI] synonym: "Ribonukleinsaeure" RELATED [ChEBI] synonym: "ribose nucleic acid" RELATED [ChEBI] synonym: "RNA" RELATED [IUPAC, UniProt] synonym: "RNS" RELATED [ChEBI] synonym: "yeast nucleic acid" RELATED [ChEBI] xref: CAS:63231-63-0 {source="ChemIDplus"} is_a: CHEBI:33696 ! nucleic acid relationship: has_part CHEBI:33792 ! canonical ribonucleoside residue relationship: has_part CHEBI:50299 ! canonical ribonucleotide residue [Term] id: CHEBI:33700 name: proteinogenic amino-acid residue subset: 3_STAR synonym: "canonical amino-acid residue" RELATED [ChEBI] synonym: "canonical amino-acid residues" RELATED [ChEBI] synonym: "common amino acid residues" RELATED [ChEBI] synonym: "proteinogenic amino-acid residues" RELATED [ChEBI] synonym: "standard amino acid residues" RELATED [ChEBI] synonym: "standard amino-acid residues" RELATED [ChEBI] is_a: CHEBI:33710 ! alpha-amino-acid residue [Term] id: CHEBI:33702 name: polyatomic cation def: "A cation consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic cations" RELATED [ChEBI] is_a: CHEBI:36358 ! polyatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:33703 name: amino-acid cation subset: 3_STAR synonym: "amino acid cation" RELATED [ChEBI] synonym: "amino acid cations" RELATED [ChEBI] synonym: "amino-acid cations" RELATED [ChEBI] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:33702 ! polyatomic cation relationship: is_conjugate_acid_of CHEBI:33709 ! amino acid [Term] id: CHEBI:33704 name: alpha-amino acid alt_id: CHEBI:10208 alt_id: CHEBI:13779 alt_id: CHEBI:22442 alt_id: CHEBI:2642 def: "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." [] subset: 3_STAR synonym: "alpha-amino acid" EXACT IUPAC_NAME [IUPAC] synonym: "alpha-amino acids" RELATED [ChEBI, JCBN] synonym: "alpha-amino carboxylic acids" RELATED [IUPAC] synonym: "Amino acid" RELATED [KEGG_COMPOUND] synonym: "Amino acids" RELATED [KEGG_COMPOUND] xref: KEGG:C00045 xref: KEGG:C05167 is_a: CHEBI:33709 ! amino acid relationship: is_conjugate_acid_of CHEBI:33558 ! alpha-amino-acid anion relationship: is_conjugate_base_of CHEBI:33719 ! alpha-amino-acid cation relationship: is_tautomer_of CHEBI:78608 ! alpha-amino-acid zwitterion [Term] id: CHEBI:33708 name: amino-acid residue def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." [] subset: 3_STAR synonym: "amino acid residue" RELATED [ChEBI] synonym: "amino acid residues" RELATED [ChEBI] synonym: "amino-acid residue" EXACT IUPAC_NAME [IUPAC] synonym: "amino-acid residues" RELATED [JCBN] is_a: CHEBI:33247 ! organic group relationship: is_conjugate_acid_of CHEBI:64898 ! anionic amino-acid residue relationship: is_conjugate_base_of CHEBI:58942 ! cationic amino-acid residue relationship: is_substituent_group_from CHEBI:33709 ! amino acid [Term] id: CHEBI:33709 name: amino acid alt_id: CHEBI:13815 alt_id: CHEBI:22477 def: "A carboxylic acid containing one or more amino groups." [] subset: 3_STAR synonym: "amino acids" RELATED [ChEBI] synonym: "Aminocarbonsaeure" RELATED [ChEBI] synonym: "Aminokarbonsaeure" RELATED [ChEBI] synonym: "Aminosaeure" RELATED [ChEBI] xref: Wikipedia:Amino_acid is_a: CHEBI:33575 ! carboxylic acid is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_acid_of CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:33703 ! amino-acid cation [Term] id: CHEBI:33710 name: alpha-amino-acid residue def: "An amino-acid residue derived from an alpha-amino acid." [] subset: 3_STAR synonym: "alpha-amino-acid residues" RELATED [ChEBI] synonym: "an alpha-amino acid residue" RELATED [UniProt] is_a: CHEBI:33708 ! amino-acid residue relationship: is_substituent_group_from CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33719 name: alpha-amino-acid cation subset: 3_STAR synonym: "alpha-amino acid cation" RELATED [ChEBI] synonym: "alpha-amino acid cations" RELATED [ChEBI] synonym: "alpha-amino-acid cations" RELATED [ChEBI] is_a: CHEBI:33703 ! amino-acid cation relationship: is_conjugate_acid_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33720 name: carbohydrate acid subset: 3_STAR synonym: "carbohydrate acid" EXACT [ChEBI] synonym: "carbohydrate acids" RELATED [ChEBI] is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:33721 ! carbohydrate acid anion [Term] id: CHEBI:33721 name: carbohydrate acid anion subset: 3_STAR synonym: "carbohydrate acid anion" EXACT [ChEBI] synonym: "carbohydrate acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:33720 ! carbohydrate acid [Term] id: CHEBI:33791 name: canonical nucleoside residue subset: 3_STAR synonym: "canonical nucleoside residues" RELATED [ChEBI] synonym: "common nucleoside residues" RELATED [CBN] synonym: "nucleoside residue" RELATED [CBN] synonym: "standard nucleoside residues" RELATED [ChEBI] is_a: CHEBI:50320 ! nucleoside residue [Term] id: CHEBI:33792 name: canonical ribonucleoside residue subset: 3_STAR synonym: "canonical ribonucleoside residues" RELATED [ChEBI] synonym: "common ribonucleoside residue" RELATED [CBN] synonym: "common ribonucleoside residues" RELATED [CBN] synonym: "N" RELATED [CBN] synonym: "Nuc" RELATED [CBN] synonym: "standard ribonucleoside residues" RELATED [ChEBI] is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33822 name: organic hydroxy compound alt_id: CHEBI:64710 def: "An organic compound having at least one hydroxy group attached to a carbon atom." [] subset: 3_STAR synonym: "hydroxy compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organic alcohol" RELATED [ChEBI] synonym: "organic hydroxy compounds" RELATED [ChEBI] is_a: CHEBI:24651 ! hydroxides is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33832 name: organic cyclic compound def: "Any organic molecule that consists of atoms connected in the form of a ring." [] subset: 3_STAR synonym: "organic cyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:33833 name: heteroarene def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." [] subset: 3_STAR synonym: "hetarenes" RELATED [IUPAC] synonym: "heteroarenes" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:33837 name: conjugated protein def: "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." [] subset: 3_STAR synonym: "complex protein" RELATED [COMe] synonym: "conjugated proteins" EXACT IUPAC_NAME [IUPAC] xref: COMe:PRX000001 is_a: CHEBI:36080 ! protein [Term] id: CHEBI:33839 name: macromolecule def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [] subset: 3_STAR synonym: "macromolecule" EXACT IUPAC_NAME [IUPAC] synonym: "macromolecules" RELATED [ChEBI] synonym: "polymer" RELATED [ChEBI] synonym: "polymer molecule" RELATED [IUPAC] synonym: "polymers" RELATED [ChEBI] xref: Wikipedia:Macromolecule is_a: CHEBI:36357 ! polyatomic entity is_a: COB:0000013 ! molecule property_value: IAO:0000111 "macromolecule" xsd:string property_value: IAO:0000118 "polymer" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/chebi.owl [Term] id: CHEBI:33853 name: phenols alt_id: CHEBI:13664 alt_id: CHEBI:13825 alt_id: CHEBI:25969 alt_id: CHEBI:2857 def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." [] subset: 3_STAR synonym: "a phenol" RELATED [UniProt] synonym: "arenols" RELATED [IUPAC] synonym: "Aryl alcohol" RELATED [KEGG_COMPOUND] synonym: "phenols" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C15584 xref: MetaCyc:Phenols xref: Wikipedia:Phenols is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CHEBI:33893 name: reagent def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." [] subset: 3_STAR synonym: "reactif" RELATED [IUPAC] synonym: "reactivo" RELATED [IUPAC] synonym: "reagent" EXACT IUPAC_NAME [IUPAC] synonym: "reagents" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:33917 name: aldohexose alt_id: CHEBI:2558 def: "A hexose with a (potential) aldehyde group at one end." [] subset: 3_STAR synonym: "aldohexose" EXACT [ChEBI] synonym: "aldohexoses" RELATED [ChEBI] is_a: CHEBI:15693 ! aldose is_a: CHEBI:18133 ! hexose [Term] id: CHEBI:33937 name: macronutrient def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." [] subset: 3_STAR synonym: "macronutrients" RELATED [ChEBI] is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:350546 name: serotonin(1+) def: "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." [] subset: 3_STAR synonym: "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "serotonin" RELATED [UniProt] synonym: "serotonin cation" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:28790 ! serotonin relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:35106 name: nitrogen hydride subset: 3_STAR synonym: "nitrogen hydrides" RELATED [ChEBI] is_a: CHEBI:35881 ! pnictogen hydride is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35107 name: azane def: "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." [] subset: 3_STAR synonym: "azanes" RELATED [ChEBI] is_a: CHEBI:35106 ! nitrogen hydride [Term] id: CHEBI:35222 name: inhibitor def: "A substance that diminishes the rate of a chemical reaction." [] subset: 3_STAR synonym: "inhibidor" RELATED [ChEBI] synonym: "inhibiteur" RELATED [ChEBI] synonym: "inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "inhibitors" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:35223 name: catalyst def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." [] subset: 3_STAR synonym: "catalizador" RELATED [ChEBI] synonym: "catalyseur" RELATED [ChEBI] synonym: "catalyst" EXACT IUPAC_NAME [IUPAC] synonym: "Katalysator" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:35238 name: amino-acid zwitterion def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." [] subset: 3_STAR synonym: "amino acid zwitterion" RELATED [ChEBI] synonym: "amino acid zwitterions" RELATED [ChEBI] synonym: "amino-acid zwitterions" RELATED [ChEBI] is_a: CHEBI:27369 ! zwitterion [Term] id: CHEBI:35267 name: quaternary ammonium ion alt_id: CHEBI:26470 alt_id: CHEBI:8693 def: "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." [] subset: 3_STAR synonym: "a quaternary ammonium" RELATED [UniProt] synonym: "Quaternary amine" RELATED [KEGG_COMPOUND] synonym: "quaternary ammonium ion" EXACT IUPAC_NAME [IUPAC] synonym: "quaternary ammonium ions" RELATED [ChEBI] xref: KEGG:C06703 is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative [Term] id: CHEBI:35274 name: ammonium ion derivative def: "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." [] subset: 3_STAR synonym: "ammonium ion derivatives" RELATED [ChEBI] synonym: "azanium ion derivative" RELATED [ChEBI] synonym: "azanium ion derivatives" RELATED [ChEBI] is_a: CHEBI:33702 ! polyatomic cation is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_parent_hydride CHEBI:28938 ! ammonium [Term] id: CHEBI:35287 name: acylcholine alt_id: CHEBI:13245 alt_id: CHEBI:22227 alt_id: CHEBI:2463 def: "A choline ester formed from choline and a carboxylic acid." [] subset: 3_STAR synonym: "acylcholines" RELATED [ChEBI] synonym: "an acylcholine" RELATED [UniProt] xref: KEGG:C01777 is_a: CHEBI:35267 ! quaternary ammonium ion [Term] id: CHEBI:35341 name: steroid alt_id: CHEBI:13687 alt_id: CHEBI:26768 alt_id: CHEBI:9263 def: "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." [] subset: 3_STAR synonym: "a steroid" RELATED [UniProt] synonym: "Steroid" EXACT [KEGG_COMPOUND] synonym: "steroids" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00377 xref: MetaCyc:Steroids is_a: CHEBI:18059 ! lipid is_a: CHEBI:51958 ! organic polycyclic compound [Term] id: CHEBI:35350 name: hydroxy steroid alt_id: CHEBI:24748 alt_id: CHEBI:5814 subset: 3_STAR synonym: "hydroxy steroids" RELATED [ChEBI] synonym: "Hydroxysteroid" RELATED [KEGG_COMPOUND] synonym: "hydroxysteroids" RELATED [ChEBI] xref: KEGG:C02159 is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:35352 name: organonitrogen compound def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." [] subset: 3_STAR synonym: "organonitrogen compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organonitrogens" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35381 name: monosaccharide alt_id: CHEBI:25407 alt_id: CHEBI:6984 def: "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." [] subset: 3_STAR synonym: "monosacarido" RELATED [ChEBI] synonym: "monosacaridos" RELATED [IUPAC] synonym: "Monosaccharid" RELATED [ChEBI] synonym: "Monosaccharide" EXACT [KEGG_COMPOUND] synonym: "monosaccharides" EXACT IUPAC_NAME [IUPAC] synonym: "Monosacharid" RELATED [ChEBI] xref: KEGG:C06698 is_a: CHEBI:16646 ! carbohydrate [Term] id: CHEBI:35406 name: oxoanion alt_id: CHEBI:33274 alt_id: CHEBI:33436 def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." [] subset: 3_STAR synonym: "oxoacid anions" RELATED [ChEBI] synonym: "oxoanion" EXACT [ChEBI] synonym: "oxoanions" RELATED [ChEBI] is_a: CHEBI:25741 ! oxide is_a: CHEBI:33273 ! polyatomic anion [Term] id: CHEBI:35472 name: anti-inflammatory drug def: "A substance that reduces or suppresses inflammation." [] subset: 3_STAR synonym: "anti-inflammatory drugs" RELATED [ChEBI] synonym: "antiinflammatory agent" RELATED [ChEBI] synonym: "antiinflammatory drug" RELATED [ChEBI] synonym: "antiinflammatory drugs" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:67079 ! anti-inflammatory agent [Term] id: CHEBI:35479 name: alkali metal salt subset: 3_STAR synonym: "alkali metal salts" RELATED [ChEBI] is_a: CHEBI:24866 ! salt is_a: CHEBI:33296 ! alkali metal molecular entity [Term] id: CHEBI:35507 name: natural product fundamental parent subset: 3_STAR synonym: "natural product fundamental parents" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33245 ! organic fundamental parent [Term] id: CHEBI:35508 name: steroid fundamental parent subset: 3_STAR synonym: "steroid fundamental parents" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid is_a: CHEBI:35507 ! natural product fundamental parent [Term] id: CHEBI:35519 name: cholane subset: 3_STAR synonym: "cholane" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:35508 ! steroid fundamental parent [Term] id: CHEBI:35524 name: sympathomimetic agent def: "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." [] subset: 3_STAR synonym: "sympathomimetic" RELATED [ChEBI] synonym: "sympathomimetics" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:35554 name: cardiovascular drug def: "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." [] subset: 3_STAR synonym: "cardiovascular agent" RELATED [ChEBI] synonym: "cardiovascular drugs" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35569 name: alpha-adrenergic agonist def: "An agent that selectively binds to and activates alpha-adrenergic receptors." [] subset: 3_STAR synonym: "alpha-adrenergic agonists" RELATED [ChEBI] synonym: "alpha-adrenergic receptor agonist" RELATED [ChEBI] synonym: "alpha-adrenoceptor agonists" RELATED [IUPHAR] is_a: CHEBI:37886 ! adrenergic agonist is_a: CHEBI:48539 ! alpha-adrenergic drug [Term] id: CHEBI:35604 name: carbon oxoanion def: "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." [] subset: 3_STAR synonym: "carbon oxoanion" EXACT [ChEBI] synonym: "carbon oxoanions" RELATED [ChEBI] synonym: "oxocarbon anion" RELATED [ChEBI] synonym: "oxocarbon anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35605 name: carbon oxoacid subset: 3_STAR synonym: "carbon oxoacids" RELATED [ChEBI] synonym: "oxoacids of carbon" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35620 name: vasodilator agent def: "A drug used to cause dilation of the blood vessels." [] subset: 3_STAR synonym: "vasodilator" RELATED [ChEBI] synonym: "vasodilator agents" RELATED [ChEBI] is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:35692 name: dicarboxylic acid alt_id: CHEBI:23692 alt_id: CHEBI:36172 alt_id: CHEBI:4501 def: "Any carboxylic acid containing two carboxy groups." [] subset: 3_STAR synonym: "Dicarboxylic acid" EXACT [KEGG_COMPOUND] synonym: "dicarboxylic acids" RELATED [ChEBI] xref: KEGG:C02028 is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35693 ! dicarboxylic acid anion [Term] id: CHEBI:35693 name: dicarboxylic acid anion subset: 3_STAR synonym: "dicarboxylic acid anion" EXACT [ChEBI] synonym: "dicarboxylic acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:35692 ! dicarboxylic acid [Term] id: CHEBI:35701 name: ester alt_id: CHEBI:23960 alt_id: CHEBI:4859 def: "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." [] subset: 3_STAR synonym: "Ester" EXACT [KEGG_COMPOUND] synonym: "esters" RELATED [ChEBI] xref: KEGG:C00287 xref: Wikipedia:Ester is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35722 name: sulfated glycosaminoglycan subset: 3_STAR synonym: "glycosaminoglycan sulfate" RELATED [ChEBI] synonym: "glycosaminoglycan sulfates" RELATED [ChEBI] synonym: "sulfated glycosaminoglycans" RELATED [ChEBI] is_a: CHEBI:18085 ! glycosaminoglycan is_a: CHEBI:35724 ! carbohydrate sulfate [Term] id: CHEBI:35724 name: carbohydrate sulfate subset: 3_STAR synonym: "carbohydrate sulfates" RELATED [ChEBI] synonym: "carbohydrate sulphates" RELATED [ChEBI] is_a: CHEBI:25704 ! organic sulfate is_a: CHEBI:26819 ! sulfuric ester is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:35757 name: monocarboxylic acid anion alt_id: CHEBI:13657 alt_id: CHEBI:25382 alt_id: CHEBI:3407 def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a monocarboxylate" RELATED [UniProt] synonym: "Carboxylate" RELATED [KEGG_COMPOUND] synonym: "Monocarboxylate" RELATED [KEGG_COMPOUND] synonym: "monocarboxylates" RELATED [ChEBI] synonym: "monocarboxylic acid anions" RELATED [ChEBI] xref: KEGG:C00060 is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:25384 ! monocarboxylic acid [Term] id: CHEBI:35881 name: pnictogen hydride subset: 3_STAR synonym: "pnictogen hydride" EXACT [ChEBI] synonym: "pnictogen hydrides" RELATED [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33302 ! pnictogen molecular entity [Term] id: CHEBI:35942 name: neurotransmitter agent def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." [] subset: 3_STAR synonym: "neurotransmitter agents" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:36078 name: cholanoid alt_id: CHEBI:22867 alt_id: CHEBI:50419 subset: 3_STAR synonym: "bile acids and derivatives" RELATED [LIPID_MAPS] synonym: "cholanoids" RELATED [ChEBI] xref: LIPID_MAPS_class:LMST04 {source="LIPID MAPS"} is_a: CHEBI:35341 ! steroid relationship: has_parent_hydride CHEBI:35519 ! cholane [Term] id: CHEBI:36080 name: protein alt_id: CHEBI:13677 alt_id: CHEBI:14911 def: "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." [] subset: 3_STAR synonym: "proteins" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33695 ! information biomacromolecule relationship: has_part CHEBI:16541 ! protein polypeptide chain [Term] id: CHEBI:36235 name: bile acid anion subset: 3_STAR synonym: "bile acid anions" RELATED [ChEBI] is_a: CHEBI:35757 ! monocarboxylic acid anion is_a: CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:36237 name: cholanic acid def: "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." [] subset: 3_STAR synonym: "cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:25312-65-6 {source="ChemIDplus"} xref: Patent:JP2008069152 xref: Reaxys:13246008 {source="Reaxys"} is_a: CHEBI:36278 ! cholanic acids [Term] id: CHEBI:36238 name: 5beta-cholanic acid subset: 3_STAR synonym: "(5beta)-cholan-24-oic acid" RELATED [ChemIDplus] synonym: "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid" RELATED [ChemIDplus] synonym: "5beta-cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] synonym: "5beta-cholanic acid" EXACT [ChemIDplus] synonym: "5beta-cholanoic acid" RELATED [ChemIDplus] synonym: "ursocholanic acid" RELATED [ChemIDplus] xref: Beilstein:3214794 {source="Beilstein"} xref: CAS:546-18-9 {source="ChemIDplus"} xref: LIPID_MAPS_instance:LMST04010441 {source="LIPID MAPS"} is_a: CHEBI:36237 ! cholanic acid is_a: CHEBI:36248 ! 5beta-cholanic acids [Term] id: CHEBI:36248 name: 5beta-cholanic acids def: "Members of the class of cholanic acids based on a 5beta-cholane skeleton." [] subset: 3_STAR is_a: CHEBI:136889 ! 5beta steroid is_a: CHEBI:36278 ! cholanic acids relationship: has_parent_hydride CHEBI:20664 ! 5beta-cholane [Term] id: CHEBI:36277 name: bile acid salt def: "A salt of a bile acid." [] subset: 3_STAR synonym: "bile acid salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:36278 name: cholanic acids alt_id: CHEBI:23166 alt_id: CHEBI:23211 subset: 1_STAR is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:47891 ! steroid acid [Term] id: CHEBI:36338 name: lepton def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." [] subset: 3_STAR synonym: "leptons" RELATED [ChEBI] is_a: CHEBI:33233 ! fundamental particle is_a: CHEBI:36340 ! fermion [Term] id: CHEBI:36339 name: baryon def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." [] subset: 3_STAR synonym: "baryons" RELATED [ChEBI] is_a: CHEBI:36340 ! fermion is_a: CHEBI:36344 ! hadron [Term] id: CHEBI:36340 name: fermion def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." [] subset: 3_STAR synonym: "fermion" EXACT IUPAC_NAME [IUPAC] synonym: "fermions" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36341 name: boson def: "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." [] subset: 3_STAR synonym: "boson" EXACT IUPAC_NAME [IUPAC] synonym: "bosons" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36342 name: subatomic particle def: "A particle smaller than an atom." [] subset: 3_STAR synonym: "subatomic particles" RELATED [ChEBI] xref: Wikipedia:Subatomic_particle is_a: BFO:0000040 ! material entity disjoint_from: COB:0000011 ! atom [Term] id: CHEBI:36343 name: composite particle def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." [] subset: 3_STAR synonym: "composite particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36344 name: hadron def: "Hadron is a subatomic particle which experiences the strong force." [] subset: 3_STAR synonym: "hadrons" RELATED [ChEBI] is_a: CHEBI:36343 ! composite particle [Term] id: CHEBI:36347 name: nuclear particle def: "A nucleus or any of its constituents in any of their energy states." [] subset: 3_STAR synonym: "nuclear particle" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36357 name: polyatomic entity def: "Any molecular entity consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:24433 ! group [Term] id: CHEBI:36358 name: polyatomic ion def: "An ion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:36586 name: carbonyl compound def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." [] subset: 3_STAR synonym: "carbonyl compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36587 ! organic oxo compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23019 ! carbonyl group [Term] id: CHEBI:36587 name: organic oxo compound def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." [] subset: 3_STAR synonym: "organic oxo compounds" RELATED [ChEBI] synonym: "oxo compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:72695 ! organic molecule relationship: has_part CHEBI:46629 ! oxo group [Term] id: CHEBI:36735 name: biladienes def: "Compounds based on a biladiene skeleton." [] subset: 3_STAR is_a: CHEBI:25046 ! linear tetrapyrrole [Term] id: CHEBI:36902 name: chalcogen hydride subset: 3_STAR synonym: "chalcogen hydride" EXACT [ChEBI] synonym: "chalcogen hydrides" RELATED [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36914 name: inorganic ion subset: 3_STAR synonym: "inorganic ions" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36915 name: inorganic cation subset: 3_STAR synonym: "inorganic cations" RELATED [ChEBI] is_a: CHEBI:36914 ! inorganic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:36916 name: cation alt_id: CHEBI:23058 alt_id: CHEBI:3473 def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." [] subset: 3_STAR synonym: "Cation" EXACT [KEGG_COMPOUND] synonym: "cation" EXACT IUPAC_NAME [ChEBI, IUPAC] synonym: "cationes" RELATED [ChEBI] synonym: "cations" RELATED [ChEBI] synonym: "Kation" RELATED [ChEBI] synonym: "Kationen" RELATED [ChEBI] xref: KEGG:C01373 is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36961 name: chalcocarbonic acid subset: 3_STAR synonym: "chalcocarbonic acid" EXACT [ChEBI] synonym: "chalcocarbonic acids" EXACT IUPAC_NAME [IUPAC] synonym: "chalcocarbonic acids" RELATED [ChEBI] is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:36962 name: organochalcogen compound def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." [] subset: 3_STAR synonym: "organochalcogen compound" EXACT [ChEBI] synonym: "organochalcogen compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36963 name: organooxygen compound def: "An organochalcogen compound containing at least one carbon-oxygen bond." [] subset: 3_STAR synonym: "organooxygen compound" EXACT [ChEBI] synonym: "organooxygen compounds" RELATED [ChEBI] xref: PMID:17586126 {source="Europe PMC"} is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:37022 name: amino-acid anion subset: 3_STAR synonym: "amino acid anion" RELATED [ChEBI] synonym: "amino acid anions" RELATED [ChEBI] synonym: "amino-acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion is_a: CHEBI:35352 ! organonitrogen compound relationship: is_conjugate_base_of CHEBI:33709 ! amino acid [Term] id: CHEBI:37163 name: glucan alt_id: CHEBI:24255 alt_id: CHEBI:5392 def: "A polysaccharide composed of glucose residues." [] subset: 3_STAR synonym: "Glucan" EXACT [KEGG_COMPOUND] synonym: "glucan" EXACT IUPAC_NAME [IUPAC] synonym: "glucans" RELATED [ChEBI] xref: CAS:9037-91-6 {source="ChemIDplus"} xref: KEGG:C01379 is_a: CHEBI:37164 ! homopolysaccharide [Term] id: CHEBI:37164 name: homopolysaccharide def: "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." [] subset: 3_STAR synonym: "homoglycan" RELATED [IUPAC] synonym: "homopolysaccharide" EXACT IUPAC_NAME [IUPAC] synonym: "homopolysaccharides" RELATED [ChEBI] is_a: CHEBI:18154 ! polysaccharide [Term] id: CHEBI:37175 name: organic hydride subset: 3_STAR synonym: "organic hydrides" RELATED [ChEBI] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37176 name: mononuclear parent hydride subset: 3_STAR synonym: "mononuclear hydride" RELATED [ChEBI] synonym: "mononuclear hydrides" RELATED [IUPAC] synonym: "mononuclear parent hydrides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37246 name: elemental sodium subset: 3_STAR is_a: CHEBI:26712 ! sodium molecular entity [Term] id: CHEBI:37395 name: mucopolysaccharide alt_id: CHEBI:25425 alt_id: CHEBI:7011 def: "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." [] subset: 3_STAR synonym: "mucopolisacarido" RELATED [ChEBI] synonym: "mucopolisacaridos" RELATED [IUPAC] synonym: "Mucopolysaccharid" RELATED [ChEBI] synonym: "Mucopolysaccharide" EXACT [KEGG_COMPOUND] synonym: "mucopolysaccharides" EXACT IUPAC_NAME [IUPAC] synonym: "Mukopolysaccharid" RELATED [ChEBI] xref: KEGG:C05114 is_a: CHEBI:18085 ! glycosaminoglycan [Term] id: CHEBI:37527 name: acid alt_id: CHEBI:13800 alt_id: CHEBI:13801 alt_id: CHEBI:22209 alt_id: CHEBI:2426 def: "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." [] subset: 3_STAR synonym: "Acid" EXACT [KEGG_COMPOUND] synonym: "acid" EXACT IUPAC_NAME [IUPAC] synonym: "acide" RELATED [IUPAC] synonym: "acido" RELATED [ChEBI] synonym: "acids" RELATED [ChEBI] synonym: "Saeure" RELATED [ChEBI] synonym: "Saeuren" RELATED [ChEBI] xref: KEGG:C00174 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:37577 name: heteroatomic molecular entity def: "A molecular entity consisting of two or more chemical elements." [] subset: 3_STAR synonym: "chemical compound" RELATED [ChEBI] synonym: "heteroatomic molecular entities" RELATED [ChEBI] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:37622 name: carboxamide alt_id: CHEBI:35354 alt_id: CHEBI:35355 def: "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." [] subset: 3_STAR synonym: "carboxamides" EXACT IUPAC_NAME [IUPAC] synonym: "carboxamides" RELATED [ChEBI] synonym: "primary carboxamide" RELATED [ChEBI] is_a: CHEBI:33256 ! primary amide is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23004 ! carbamoyl group [Term] id: CHEBI:37661 name: glucopyranose subset: 3_STAR synonym: "glucopyranose" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:17234 ! glucose [Term] id: CHEBI:37826 name: sulfuric acid derivative subset: 3_STAR synonym: "sulfuric acid derivative" EXACT [ChEBI] synonym: "sulfuric acid derivatives" RELATED [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative relationship: has_functional_parent CHEBI:26836 ! sulfuric acid [Term] id: CHEBI:37838 name: carboacyl group def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "carboacyl groups" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl group" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl groups" RELATED [IUPAC] is_a: CHEBI:22221 ! acyl group relationship: is_substituent_group_from CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:37886 name: adrenergic agonist def: "An agent that selectively binds to and activates adrenergic receptors." [] subset: 3_STAR synonym: "adrenergic agonists" RELATED [ChEBI] synonym: "adrenergic receptor agonist" RELATED [ChEBI] synonym: "adrenoceptor agonists" RELATED [IUPHAR] synonym: "adrenomimetic" RELATED [ChEBI] synonym: "adrenomimetics" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:37962 name: adrenergic agent def: "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." [] subset: 3_STAR synonym: "adrenergic agents" RELATED [ChEBI] synonym: "adrenergic drug" RELATED [ChEBI] synonym: "adrenergic drugs" RELATED [ChEBI] synonym: "adrenergic neuron agents" RELATED [ChEBI] synonym: "adrenergics" RELATED [ChEBI] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38077 name: polypyrrole def: "A compound composed of two or more pyrrole units." [] subset: 3_STAR synonym: "poly(pyrrole)s" RELATED [ChEBI] synonym: "polypyrroles" RELATED [ChEBI] synonym: "PPys" RELATED [ChEBI] xref: Beilstein:8538310 {source="Beilstein"} is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:38101 name: organonitrogen heterocyclic compound def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." [] subset: 3_STAR synonym: "heterocyclic organonitrogen compounds" RELATED [ChEBI] synonym: "organonitrogen heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:38166 name: organic heteropolycyclic compound alt_id: CHEBI:25429 alt_id: CHEBI:38075 subset: 3_STAR synonym: "organic heteropolycyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33671 ! heteropolycyclic compound [Term] id: CHEBI:38180 name: polycyclic heteroarene subset: 3_STAR synonym: "polycyclic heteroarenes" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene [Term] id: CHEBI:38323 name: cholinergic drug def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." [] subset: 3_STAR synonym: "cholinergic agent" RELATED [ChEBI] synonym: "cholinergic drugs" RELATED [ChEBI] synonym: "cholinomimetic" RELATED [ChEBI] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38324 name: cholinergic agonist def: "Any drug that binds to and activates cholinergic receptors." [] subset: 3_STAR synonym: "acetylcholine agonist" RELATED [ChEBI] synonym: "acetylcholine agonists" RELATED [ChEBI] synonym: "acetylcholine receptor agonist" RELATED [IUPHAR] synonym: "cholinergic agonists" RELATED [ChEBI] synonym: "cholinomimetic" RELATED [ChEBI] synonym: "cholinomimetics" RELATED [ChEBI] is_a: CHEBI:38323 ! cholinergic drug [Term] id: CHEBI:38325 name: muscarinic agonist def: "Any drug that binds to and activates a muscarinic cholinergic receptor." [] subset: 3_STAR synonym: "muscarinic acetylcholine receptor agonist" RELATED [ChEBI] synonym: "muscarinic agonists" RELATED [ChEBI] synonym: "muscarinic cholinergic agonist" RELATED [ChEBI] synonym: "muscarinic cholinergic agonists" RELATED [ChEBI] is_a: CHEBI:38324 ! cholinergic agonist [Term] id: CHEBI:38631 name: aminoalkylindole alt_id: CHEBI:22503 alt_id: CHEBI:24792 subset: 3_STAR synonym: "aminoalkylindoles" RELATED [ChEBI] is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:38700 name: organic sodium salt subset: 3_STAR synonym: "organic sodium salt" EXACT [ChEBI] synonym: "organic sodium salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:26714 ! sodium salt [Term] id: CHEBI:38716 name: carboxylic acid dianion def: "Any dianion containing at least one carboxy group." [] subset: 3_STAR synonym: "carboxylic acid dianion" EXACT [ChEBI] synonym: "carboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion [Term] id: CHEBI:38958 name: indole alkaloid alt_id: CHEBI:24795 alt_id: CHEBI:5901 def: "An alkaloid containing an indole skeleton." [] subset: 3_STAR synonym: "Indole alkaloid" EXACT [KEGG_COMPOUND] synonym: "indole alkaloids" RELATED [ChEBI] xref: KEGG:C06073 xref: Wikipedia:Indole_alkaloid is_a: CHEBI:22315 ! alkaloid relationship: has_part CHEBI:73398 ! indole skeleton [Term] id: CHEBI:39141 name: Bronsted acid def: "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." [] subset: 3_STAR synonym: "acide de Bronsted" RELATED [IUPAC] synonym: "Bronsted acid" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Saeure" RELATED [ChEBI] synonym: "donneur d'hydron" RELATED [IUPAC] synonym: "hydron donor" RELATED [IUPAC] is_a: CHEBI:17891 ! donor is_a: CHEBI:37527 ! acid [Term] id: CHEBI:39142 name: Bronsted base def: "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." [] subset: 3_STAR synonym: "accepteur d'hydron" RELATED [IUPAC] synonym: "base de Bronsted" RELATED [IUPAC] synonym: "Bronsted base" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Base" RELATED [ChEBI] synonym: "hydron acceptor" RELATED [IUPAC] is_a: CHEBI:15339 ! acceptor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39144 name: Lewis base def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." [] subset: 3_STAR synonym: "base de Lewis" RELATED [IUPAC] synonym: "donneur d'une paire d'electrons" RELATED [ChEBI] synonym: "electron donor" RELATED [ChEBI] synonym: "Lewis base" EXACT IUPAC_NAME [IUPAC] synonym: "Lewis-Base" RELATED [ChEBI] is_a: CHEBI:17891 ! donor is_a: CHEBI:22695 ! base [Term] id: CHEBI:41609 name: carbonate alt_id: CHEBI:29201 alt_id: CHEBI:41605 subset: 3_STAR synonym: "[CO3](2-)" RELATED [IUPAC] synonym: "carbonate" EXACT [IUPAC] synonym: "CARBONATE ION" RELATED [PDBeChem] synonym: "CO3(2-)" RELATED [ChEBI] synonym: "Karbonat" RELATED [ChEBI] synonym: "trioxidocarbonate(2-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3600898 {source="Beilstein"} xref: CAS:3812-32-6 {source="ChemIDplus"} xref: Gmelin:1559 {source="Gmelin"} xref: PDBeChem:CO3 is_a: CHEBI:35604 ! carbon oxoanion relationship: is_conjugate_base_of CHEBI:17544 ! hydrogencarbonate [Term] id: CHEBI:4167 name: D-glucopyranose def: "A glucopyranose having D-configuration." [] subset: 3_STAR synonym: "D-Glc" RELATED [ChEBI] synonym: "D-Glcp" RELATED [ChEBI] synonym: "D-glucopyranose" EXACT IUPAC_NAME [IUPAC] synonym: "D-Glucose" RELATED [KEGG_COMPOUND] synonym: "D-glucose" RELATED [UniProt] synonym: "Dextrose" RELATED [KEGG_COMPOUND] synonym: "Glc-OH" RELATED [ChEBI] synonym: "Glucose" RELATED [KEGG_COMPOUND] synonym: "glucose" RELATED [ChEBI] synonym: "Grape sugar" RELATED [KEGG_COMPOUND] synonym: "WURCS=2.0/1,1,0/[a2122h-1x_1-5]/1/" RELATED [GlyTouCan] xref: CAS:2280-44-6 {source="ChemIDplus"} xref: GlyGen:G15021LG xref: GlyTouCan:G15021LG xref: Gmelin:83256 {source="Gmelin"} xref: HMDB:HMDB0000122 xref: KEGG:C00031 xref: KEGG:D00009 xref: KNApSAcK:C00001122 xref: MetaCyc:D-Glucose xref: PMID:15987845 {source="Europe PMC"} xref: PMID:16901854 {source="Europe PMC"} xref: PMID:17336832 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17928662 {source="Europe PMC"} xref: PMID:19913595 {source="Europe PMC"} xref: PMID:26812026 {source="Europe PMC"} xref: PMID:32619908 {source="Europe PMC"} xref: PMID:7524207 {source="Europe PMC"} xref: PMID:9140037 {source="Europe PMC"} xref: PMID:9501190 {source="Europe PMC"} xref: PMID:9506998 {source="Europe PMC"} xref: PMID:9545565 {source="Europe PMC"} xref: Reaxys:1281604 {source="Reaxys"} xref: Wikipedia:Glucose is_a: CHEBI:17634 ! D-glucose is_a: CHEBI:37661 ! glucopyranose relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:4194 name: D-hexose def: "A hexose that has D-configuration at position 5." [] subset: 3_STAR synonym: "a D-hexose" RELATED [UniProt] synonym: "D-hexopyranose" EXACT IUPAC_NAME [IUPAC] synonym: "D-Hexose" EXACT [KEGG_COMPOUND] synonym: "D-hexoses" RELATED [ChEBI] xref: KEGG:C00738 is_a: CHEBI:18133 ! hexose [Term] id: CHEBI:43176 name: hydroxy group alt_id: CHEBI:24706 alt_id: CHEBI:43171 subset: 3_STAR synonym: "-OH" RELATED [IUPAC] synonym: "hydroxy" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROXY GROUP" EXACT [PDBeChem] synonym: "hydroxy group" EXACT [UniProt] synonym: "hydroxyl" RELATED [ChEBI] synonym: "hydroxyl group" RELATED [ChEBI] xref: PDBeChem:OH is_a: CHEBI:33246 ! inorganic group [Term] id: CHEBI:45696 name: hydrogensulfate alt_id: CHEBI:29199 alt_id: CHEBI:45693 subset: 3_STAR synonym: "[SO3(OH)](-)" RELATED [IUPAC] synonym: "HSO4(-)" RELATED [IUPAC] synonym: "HYDROGEN SULFATE" RELATED [PDBeChem] synonym: "hydrogen(tetraoxidosulfate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogensulfate" EXACT [IUPAC] synonym: "hydrogensulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidotrioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:2121 {source="Gmelin"} is_a: CHEBI:33482 ! sulfur oxoanion relationship: is_conjugate_acid_of CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:26836 ! sulfuric acid [Term] id: CHEBI:46629 name: oxo group alt_id: CHEBI:29353 alt_id: CHEBI:44607 subset: 3_STAR synonym: "=O" RELATED [IUPAC] synonym: "oxo" EXACT IUPAC_NAME [IUPAC] synonym: "OXO GROUP" EXACT [PDBeChem] xref: PDBeChem:O is_a: CHEBI:33246 ! inorganic group [Term] id: CHEBI:46662 name: mineral def: "In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals')." [] subset: 3_STAR synonym: "mineral" EXACT [ChEBI] synonym: "Minerale" RELATED [ChEBI] synonym: "minerales" RELATED [ChEBI] synonym: "minerals" RELATED [ChEBI] synonym: "mineraux" RELATED [ChEBI] xref: Wikipedia:Mineral is_a: CHEBI:59999 ! chemical substance [Term] id: CHEBI:46723 name: phosphate mineral subset: 3_STAR synonym: "phosphate minerals" RELATED [ChEBI] is_a: CHEBI:46662 ! mineral [Term] id: CHEBI:46787 name: solvent def: "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." [] subset: 3_STAR synonym: "Loesungsmittel" RELATED [ChEBI] synonym: "solvant" RELATED [ChEBI] synonym: "solvents" RELATED [ChEBI] xref: Wikipedia:Solvent is_a: CHEBI:33232 ! application is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:46883 name: carboxy group alt_id: CHEBI:23025 alt_id: CHEBI:41420 subset: 3_STAR synonym: "-C(O)OH" RELATED [IUPAC] synonym: "-CO2H" RELATED [ChEBI] synonym: "-COOH" RELATED [IUPAC] synonym: "carboxy" EXACT IUPAC_NAME [IUPAC] synonym: "CARBOXY GROUP" EXACT [PDBeChem] synonym: "carboxyl group" RELATED [ChEBI] xref: PDBeChem:FMT is_a: CHEBI:33249 ! organyl group [Term] id: CHEBI:47622 name: acetate ester alt_id: CHEBI:13244 alt_id: CHEBI:13799 alt_id: CHEBI:22189 alt_id: CHEBI:2406 def: "Any carboxylic ester where the carboxylic acid component is acetic acid." [] subset: 3_STAR synonym: "acetate" RELATED [ChEBI] synonym: "acetate esters" RELATED [ChEBI] synonym: "acetates" RELATED [ChEBI] synonym: "Acetic ester" RELATED [KEGG_COMPOUND] synonym: "Acetyl ester" RELATED [KEGG_COMPOUND] synonym: "acetyl esters" RELATED [ChEBI] synonym: "an acetyl ester" RELATED [UniProt] xref: KEGG:C01883 xref: Wikipedia:Acetate#Esters is_a: CHEBI:33308 ! carboxylic ester relationship: has_functional_parent CHEBI:15366 ! acetic acid [Term] id: CHEBI:47891 name: steroid acid def: "Any steroid substituted by at least one carboxy group." [] subset: 3_STAR synonym: "steroid acids" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid is_a: CHEBI:64709 ! organic acid relationship: is_conjugate_acid_of CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:48154 name: sulfur oxide subset: 3_STAR synonym: "oxides of sulfur" RELATED [ChEBI] synonym: "Schwefeloxide" RELATED [ChEBI] synonym: "sulfur oxides" RELATED [ChEBI] is_a: CHEBI:24836 ! inorganic oxide is_a: CHEBI:26835 ! sulfur molecular entity [Term] id: CHEBI:48354 name: polar solvent def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." [] subset: 3_STAR synonym: "polar solvent" EXACT IUPAC_NAME [IUPAC] synonym: "polar solvents" RELATED [ChEBI] is_a: CHEBI:46787 ! solvent [Term] id: CHEBI:48356 name: protic solvent def: "A polar solvent that is capable of acting as a hydron (proton) donor." [] subset: 3_STAR synonym: "protogenic solvent" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:39141 ! Bronsted acid is_a: CHEBI:48354 ! polar solvent [Term] id: CHEBI:48359 name: protophilic solvent def: "Solvent that is capable of acting as a hydron (proton) acceptor." [] subset: 3_STAR synonym: "HBA solvent" RELATED [ChEBI] synonym: "hydrogen bond acceptor solvent" RELATED [ChEBI] synonym: "protophilic solvent" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:39142 ! Bronsted base is_a: CHEBI:48354 ! polar solvent [Term] id: CHEBI:48360 name: amphiprotic solvent def: "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases." [] subset: 3_STAR synonym: "amphiprotic solvent" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:48356 ! protic solvent is_a: CHEBI:48359 ! protophilic solvent [Term] id: CHEBI:48539 name: alpha-adrenergic drug def: "Any drug that acts on an alpha-adrenergic receptor." [] subset: 3_STAR synonym: "alpha-adrenergic drugs" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:48705 name: agonist def: "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." [] subset: 3_STAR synonym: "agonist" EXACT IUPAC_NAME [IUPAC] synonym: "agonista" RELATED [ChEBI] synonym: "agoniste" RELATED [ChEBI] synonym: "agonists" RELATED [ChEBI] is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:49637 name: hydrogen atom alt_id: CHEBI:24634 alt_id: CHEBI:49636 subset: 3_STAR synonym: "1H" RELATED [IUPAC] synonym: "H" RELATED [IUPAC] synonym: "hidrogeno" RELATED [ChEBI] synonym: "hydrogen" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen" RELATED [ChEBI] synonym: "hydrogene" RELATED [ChEBI] synonym: "Wasserstoff" RELATED [ChEBI] xref: WebElements:H is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33559 ! s-block element atom relationship: RO:0000087 CHEBI:33937 ! has role macronutrient [Term] id: CHEBI:50047 name: organic amino compound def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." [] subset: 3_STAR synonym: "organic amino compounds" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35352 ! organonitrogen compound relationship: has_parent_hydride CHEBI:16134 ! ammonia relationship: RO:0000087 CHEBI:39142 ! has role Bronsted base [Term] id: CHEBI:50160 name: steroid acid anion def: "Any anion formed by loss of a proton from a steroid acid." [] subset: 3_STAR synonym: "steroid acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:47891 ! steroid acid [Term] id: CHEBI:50297 name: canonical nucleotide residue subset: 3_STAR synonym: "canonical nucleotide residues" RELATED [ChEBI] is_a: CHEBI:50319 ! nucleotide residue [Term] id: CHEBI:50299 name: canonical ribonucleotide residue subset: 3_STAR synonym: "canonical ribonucleotide residues" RELATED [ChEBI] is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50312 name: onium compound subset: 1_STAR is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:50313 name: onium cation def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." [] subset: 3_STAR synonym: "onium cations" EXACT IUPAC_NAME [IUPAC] synonym: "onium cations" RELATED [ChEBI] synonym: "onium ion" RELATED [ChEBI] synonym: "onium ions" RELATED [ChEBI] is_a: CHEBI:50312 ! onium compound [Term] id: CHEBI:50319 name: nucleotide residue subset: 3_STAR synonym: "nucleotide residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50320 name: nucleoside residue subset: 3_STAR synonym: "nucleoside residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50514 name: vasoconstrictor agent def: "Drug used to cause constriction of the blood vessels." [] subset: 3_STAR is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:50860 name: organic molecular entity alt_id: CHEBI:25700 alt_id: CHEBI:33244 def: "Any molecular entity that contains carbon." [] subset: 3_STAR synonym: "organic compounds" RELATED [ChEBI] synonym: "organic entity" RELATED [ChEBI] synonym: "organic molecular entities" RELATED [ChEBI] is_a: CHEBI:33582 ! carbon group molecular entity relationship: has_part CHEBI:27594 ! carbon atom [Term] id: CHEBI:50906 name: role def: "A role is particular behaviour which a material entity may exhibit." [] subset: 3_STAR [Term] id: CHEBI:50910 name: neurotoxin alt_id: CHEBI:50911 def: "A poison that interferes with the functions of the nervous system." [] subset: 3_STAR synonym: "agente neurotoxico" RELATED [ChEBI] synonym: "nerve poison" RELATED [ChEBI] synonym: "nerve poisons" RELATED [ChEBI] synonym: "neurotoxic agent" RELATED [ChEBI] synonym: "neurotoxic agents" RELATED [ChEBI] synonym: "neurotoxicant" RELATED [ChEBI] synonym: "neurotoxins" RELATED [ChEBI] xref: Wikipedia:Neurotoxin is_a: CHEBI:52209 ! aetiopathogenetic role is_a: CHEBI:64909 ! poison [Term] id: CHEBI:50994 name: primary amino compound def: "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." [] subset: 3_STAR synonym: "primary amino compounds" RELATED [ChEBI] is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_base_of CHEBI:65296 ! primary ammonium ion [Term] id: CHEBI:51086 name: chemical role def: "A role played by the molecular entity or part thereof within a chemical context." [] subset: 3_STAR is_a: CHEBI:50906 ! role [Term] id: CHEBI:51143 name: nitrogen molecular entity alt_id: CHEBI:25556 alt_id: CHEBI:7594 subset: 3_STAR synonym: "nitrogen compounds" RELATED [ChEBI] synonym: "nitrogen molecular entities" RELATED [ChEBI] synonym: "Nitrogenous compounds" RELATED [KEGG_COMPOUND] xref: KEGG:C06061 is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_part CHEBI:25555 ! nitrogen atom [Term] id: CHEBI:51151 name: dipolar compound def: "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." [] subset: 3_STAR synonym: "dipolar compounds" RELATED [ChEBI] is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:51422 name: organodiyl group def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." [] subset: 3_STAR synonym: "organodiyl groups" RELATED [ChEBI] is_a: CHEBI:51446 ! organic divalent group [Term] id: CHEBI:51446 name: organic divalent group subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51447 name: organic univalent group subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51958 name: organic polycyclic compound subset: 3_STAR synonym: "organic polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:52206 name: biochemical role def: "A biological role played by the molecular entity or part thereof within a biochemical context." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52209 name: aetiopathogenetic role def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." [] subset: 3_STAR synonym: "etiopathogenetic agent" RELATED [ChEBI] synonym: "etiopathogenetic role" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52210 name: pharmacological role def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52211 name: physiological role subset: 1_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52217 name: pharmaceutical alt_id: CHEBI:33293 alt_id: CHEBI:33294 def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." [] subset: 3_STAR synonym: "farmaco" RELATED [ChEBI] synonym: "medicament" RELATED [ChEBI] synonym: "pharmaceuticals" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:52254 name: apatite def: "A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl." [] subset: 3_STAR synonym: "hydroxyapatite" RELATED [ChEBI] xref: HMDB:HMDB0033610 is_a: CHEBI:46723 ! phosphate mineral [Term] id: CHEBI:52255 name: hydroxylapatite def: "A phosphate mineral with the formula Ca5(PO4)3(OH)." [] subset: 3_STAR is_a: CHEBI:52254 ! apatite [Term] id: CHEBI:52625 name: inorganic hydroxy compound subset: 3_STAR synonym: "inorganic hydroxides" RELATED [ChEBI] is_a: CHEBI:24651 ! hydroxides is_a: CHEBI:24835 ! inorganic molecular entity [Term] id: CHEBI:52845 name: cyclic organic group def: "An organic group that consists of a closed ring. It may be a substituent or a skeleton." [] subset: 3_STAR synonym: "cyclic organic groups" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:53000 name: epitope def: "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." [] subset: 3_STAR synonym: "antigenic determinant" RELATED [ChEBI] synonym: "epitope function" RELATED [ChEBI] synonym: "epitope role" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:53309 name: polyanionic macromolecule def: "A polymer carrying multiple negative charges." [] subset: 3_STAR synonym: "polyanion" RELATED [ChEBI] synonym: "polyanions" RELATED [SUBMITTER] is_a: CHEBI:53368 ! ionic macromolecule [Term] id: CHEBI:53368 name: ionic macromolecule def: "A macromolecule containing ionic groups." [] subset: 3_STAR synonym: "ionic polymer" RELATED [ChEBI] synonym: "polyionic macromolecule" RELATED [ChEBI] is_a: CHEBI:33839 ! macromolecule [Term] id: CHEBI:5391 name: glucagon def: "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." [] subset: 3_STAR synonym: "Glucagon" EXACT [KEGG_COMPOUND] synonym: "glucagon" RELATED INN [ChemIDplus] synonym: "Glucagone" RELATED [ChemIDplus] synonym: "glucagonum" RELATED INN [ChemIDplus] synonym: "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr" RELATED [ChEBI] synonym: "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr" RELATED [ChemIDplus] synonym: "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT" RELATED [ChEBI] synonym: "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine" EXACT IUPAC_NAME [IUPAC] xref: CAS:16941-32-5 {source="ChemIDplus"} xref: CAS:9007-92-5 {source="ChemIDplus", source="KEGG COMPOUND"} xref: Drug_Central:2994 {source="DrugCentral"} xref: DrugBank:DB00040 xref: KEGG:C01501 xref: KEGG:D00116 xref: PMID:21940356 {source="Europe PMC"} xref: PMID:22014161 {source="Europe PMC"} xref: PMID:22154917 {source="Europe PMC"} xref: PMID:22166985 {source="Europe PMC"} xref: PMID:22167521 {source="Europe PMC"} xref: PMID:22214853 {source="Europe PMC"} xref: PMID:22227186 {source="Europe PMC"} xref: PMID:22286080 {source="Europe PMC"} xref: PMID:22294753 {source="Europe PMC"} xref: PMID:22318544 {source="Europe PMC"} xref: PMID:22334714 {source="Europe PMC"} xref: PMID:22399501 {source="Europe PMC"} xref: PMID:22438981 {source="Europe PMC"} xref: PMID:22454291 {source="Europe PMC"} xref: Reaxys:13191924 {source="Reaxys"} xref: Wikipedia:Glucagon is_a: CHEBI:25905 ! peptide hormone [Term] id: CHEBI:5686 name: heterocyclic compound def: "A cyclic compound having as ring members atoms of at least two different elements." [] subset: 3_STAR synonym: "compuesto heterociclico" RELATED [IUPAC] synonym: "compuestos heterociclicos" RELATED [IUPAC] synonym: "heterocycle" RELATED [ChEBI] synonym: "Heterocyclic compound" EXACT [KEGG_COMPOUND] synonym: "heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:57887 name: tryptaminium def: "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." [] subset: 3_STAR synonym: "2-(1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "tryptamine" RELATED [UniProt] synonym: "tryptaminium cation" RELATED [ChEBI] synonym: "tryptaminium(1+)" RELATED [ChEBI] xref: Gmelin:533978 {source="Gmelin"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:65296 ! primary ammonium ion relationship: is_conjugate_acid_of CHEBI:16765 ! tryptamine relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:57977 name: bilirubin(2-) def: "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." [] subset: 3_STAR synonym: "(4Z,15Z)-bilirubin IXalpha" RELATED [UniProt] synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate" RELATED [ChEBI] synonym: "bilirubin dianion" RELATED [ChEBI] xref: Beilstein:4083310 {source="Beilstein"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:28965 ! dicarboxylic acid dianion is_a: CHEBI:59252 ! linear tetrapyrrole anion relationship: is_conjugate_base_of CHEBI:16990 ! bilirubin IXalpha relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:58942 name: cationic amino-acid residue def: "An amino-acid residue protonated on nitrogen." [] subset: 3_STAR synonym: "amino acid cation residue" RELATED [ChEBI] synonym: "amino acid cation residues" RELATED [ChEBI] synonym: "amino-acid cation residue" RELATED [ChEBI] synonym: "amino-acid cation residues" RELATED [ChEBI] synonym: "cationic amino acid residue" RELATED [ChEBI] synonym: "cationic amino acid residues" RELATED [ChEBI] synonym: "cationic amino-acid residues" RELATED [ChEBI] is_a: CHEBI:64769 ! organic cationic group relationship: is_conjugate_acid_of CHEBI:33708 ! amino-acid residue [Term] id: CHEBI:58958 name: organosulfate oxoanion def: "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." [] subset: 3_STAR synonym: "organosulfate oxoanions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:33482 ! sulfur oxoanion relationship: has_functional_parent CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:25704 ! organic sulfate [Term] id: CHEBI:59252 name: linear tetrapyrrole anion def: "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." [] subset: 3_STAR synonym: "acyclic tetrapyrrole anion" RELATED [ChEBI] synonym: "acyclic tetrapyrrole anions" RELATED [ChEBI] synonym: "linear tetrapyrrole anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion [Term] id: CHEBI:59740 name: nucleophilic reagent def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." [] subset: 3_STAR synonym: "nucleophile" RELATED [ChEBI] synonym: "nucleophiles" RELATED [ChEBI] synonym: "nucleophilic reagents" RELATED [ChEBI] is_a: CHEBI:33893 ! reagent is_a: CHEBI:39144 ! Lewis base [Term] id: CHEBI:59999 name: chemical substance def: "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." [] subset: 3_STAR synonym: "Chemische Substanz" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:60004 name: mixture def: "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." [] subset: 3_STAR synonym: "Mischung" RELATED [ChEBI] is_a: CHEBI:59999 ! chemical substance [Term] id: CHEBI:60027 name: polymer def: "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." [] subset: 3_STAR synonym: "Kunststoff" RELATED [ChEBI] synonym: "Polymer" EXACT [ChEBI] xref: Wikipedia:Polymer is_a: CHEBI:60004 ! mixture relationship: has_part CHEBI:33839 ! macromolecule [Term] id: CHEBI:60164 name: ionic polymer def: "An ionic polymer is a polymer, composed of ionic macromolecules." [] subset: 3_STAR synonym: "polyionic polymer" RELATED [ChEBI] is_a: CHEBI:60027 ! polymer relationship: has_part CHEBI:53368 ! ionic macromolecule [Term] id: CHEBI:60242 name: monovalent inorganic cation def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." [] subset: 3_STAR synonym: "a monovalent cation" RELATED [UniProt] is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:60466 name: peptide zwitterion def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." [] subset: 3_STAR synonym: "a peptide" RELATED [UniProt] synonym: "peptide zwitterions" RELATED [ChEBI] is_a: CHEBI:27369 ! zwitterion relationship: is_tautomer_of CHEBI:16670 ! peptide [Term] id: CHEBI:61120 name: nucleobase-containing molecular entity def: "Any compound that has a nucleobase as a part." [] subset: 3_STAR synonym: "nucleobase-containing compound" RELATED [SUBMITTER] synonym: "nucleobase-containing compounds" RELATED [ChEBI] synonym: "nucleobase-containing molecular entities" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_functional_parent CHEBI:18282 ! nucleobase [Term] id: CHEBI:61469 name: polyanionic polymer def: "A polymer, composed of polyanion macromolecules." [] subset: 3_STAR synonym: "polyanion" RELATED [ChEBI] synonym: "polyanions" RELATED [ChEBI] is_a: CHEBI:60164 ! ionic polymer relationship: has_part CHEBI:53309 ! polyanionic macromolecule [Term] id: CHEBI:63248 name: oxidising agent def: "A substance that removes electrons from another reactant in a redox reaction." [] subset: 3_STAR synonym: "oxidant" RELATED [ChEBI] synonym: "oxidants" RELATED [ChEBI] synonym: "oxidiser" RELATED [ChEBI] synonym: "oxidisers" RELATED [ChEBI] synonym: "oxidising agents" RELATED [ChEBI] synonym: "oxidizer" RELATED [ChEBI] synonym: "oxidizers" RELATED [ChEBI] synonym: "oxidizing agent" RELATED [ChEBI] synonym: "oxidizing agents" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:63299 name: carbohydrate derivative def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." [] subset: 3_STAR synonym: "carbohydrate derivatives" RELATED [ChEBI] synonym: "derivatised carbohydrate" RELATED [ChEBI] synonym: "derivatised carbohydrates" RELATED [ChEBI] synonym: "derivatized carbohydrate" RELATED [ChEBI] synonym: "derivatized carbohydrates" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives relationship: has_functional_parent CHEBI:16646 ! carbohydrate [Term] id: CHEBI:63436 name: carbohydrate acid derivative def: "A carbohydrate derivative that is formally obtained from a carbohydrate acid." [] subset: 3_STAR synonym: "carbohydrate acid derivatives" RELATED [ChEBI] is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:33720 ! carbohydrate acid relationship: is_conjugate_acid_of CHEBI:63551 ! carbohydrate acid derivative anion [Term] id: CHEBI:63534 name: monoamine def: "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." [] subset: 3_STAR synonym: "monoamines" RELATED [ChEBI] synonym: "naturally occurring monoamine" RELATED [ChEBI] synonym: "naturally occurring monoamines" RELATED [ChEBI] xref: PMID:21822758 {source="Europe PMC"} xref: PMID:21993877 {source="Europe PMC"} xref: PMID:22005599 {source="Europe PMC"} xref: PMID:22082101 {source="Europe PMC"} xref: PMID:22153577 {source="Europe PMC"} xref: PMID:22213370 {source="Europe PMC"} xref: PMID:22218931 {source="Europe PMC"} xref: PMID:22342987 {source="Europe PMC"} xref: PMID:22371656 {source="Europe PMC"} is_a: CHEBI:64365 ! aralkylamino compound [Term] id: CHEBI:63551 name: carbohydrate acid derivative anion def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." [] subset: 3_STAR synonym: "carbohydrate acid anion derivative" RELATED [ChEBI] synonym: "carbohydrate acid anion derivatives" RELATED [ChEBI] synonym: "carbohydrate acid derivative anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: has_functional_parent CHEBI:33721 ! carbohydrate acid anion relationship: is_conjugate_base_of CHEBI:63436 ! carbohydrate acid derivative [Term] id: CHEBI:64047 name: food additive def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." [] subset: 3_STAR synonym: "food additives" RELATED [ChEBI] xref: Wikipedia:Food_additive is_a: CHEBI:33232 ! application is_a: CHEBI:78295 ! food component [Term] id: CHEBI:64049 name: food acidity regulator def: "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." [] subset: 3_STAR synonym: "acidity regulator" RELATED [ChEBI] synonym: "acidity regulators" RELATED [ChEBI] synonym: "food acidity regulators" RELATED [ChEBI] synonym: "pH control agent" RELATED [ChEBI] synonym: "pH control agents" RELATED [ChEBI] xref: Wikipedia:Acidity_regulator is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:64365 name: aralkylamino compound def: "An organic amino compound in which an aminoalkyl group is linked to an arene." [] subset: 3_STAR synonym: "aralkylamino compounds" RELATED [ChEBI] is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:64628 name: somatostatin def: "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." [] subset: 3_STAR synonym: "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]" RELATED [ChEBI] synonym: "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide" EXACT IUPAC_NAME [IUPAC] synonym: "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide" RELATED [ChemIDplus] synonym: "somatostatin" RELATED INN [KEGG_DRUG] synonym: "Somatostatin-1" RELATED [KEGG_COMPOUND] synonym: "Somatostatin-14" RELATED [KEGG_COMPOUND] synonym: "somatostatina" RELATED INN [ChemIDplus] synonym: "somatostatine" RELATED INN [ChemIDplus] synonym: "somatostatinum" RELATED INN [ChemIDplus] synonym: "Synthetic growth hormone release-inhibiting hormone" RELATED [ChemIDplus] xref: CAS:38916-34-6 {source="ChemIDplus", source="KEGG DRUG"} xref: Drug_Central:2997 {source="DrugCentral"} xref: HMDB:HMDB0013072 xref: KEGG:C16022 xref: KEGG:D07431 xref: LINCS:LSM-5326 xref: PMID:21922516 {source="Europe PMC"} xref: PMID:22129035 {source="Europe PMC"} xref: PMID:22147011 {source="Europe PMC"} xref: PMID:22251942 {source="Europe PMC"} xref: PMID:22483686 {source="Europe PMC"} xref: PMID:22509294 {source="Europe PMC"} xref: Reaxys:10148626 {source="Reaxys"} xref: Wikipedia:Somatostatin is_a: CHEBI:24533 ! heterodetic cyclic peptide is_a: CHEBI:25905 ! peptide hormone [Term] id: CHEBI:64708 name: one-carbon compound def: "An organic molecular entity containing a single carbon atom (C1)." [] subset: 3_STAR synonym: "one-carbon compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64709 name: organic acid def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." [] subset: 3_STAR synonym: "organic acids" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64766 name: cationic group def: "A group that carries an overall positive charge." [] subset: 3_STAR synonym: "cationic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group [Term] id: CHEBI:64767 name: anionic group def: "A group that carries an overall negative charge." [] subset: 3_STAR synonym: "anionic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group [Term] id: CHEBI:64769 name: organic cationic group def: "A cationic group that contains carbon." [] subset: 3_STAR synonym: "organic cationic groups" RELATED [ChEBI] is_a: CHEBI:64766 ! cationic group relationship: is_conjugate_acid_of CHEBI:33247 ! organic group [Term] id: CHEBI:64775 name: organic anionic group def: "An anionic group that contains carbon." [] subset: 3_STAR synonym: "organic anionic groups" RELATED [ChEBI] is_a: CHEBI:64767 ! anionic group relationship: is_conjugate_base_of CHEBI:33247 ! organic group [Term] id: CHEBI:64898 name: anionic amino-acid residue def: "An amino-acid residue carrying an overall negative charge." [] subset: 3_STAR synonym: "amino acid anion residue" RELATED [ChEBI] synonym: "amino acid anion residues" RELATED [ChEBI] synonym: "amino-acid anion residue" RELATED [ChEBI] synonym: "amino-acid anion residues" RELATED [ChEBI] synonym: "anionic amino acid residue" RELATED [ChEBI] synonym: "anionic amino acid residues" RELATED [ChEBI] is_a: CHEBI:64775 ! organic anionic group relationship: is_conjugate_base_of CHEBI:33708 ! amino-acid residue [Term] id: CHEBI:64909 name: poison def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." [] subset: 3_STAR synonym: "poisonous agent" RELATED [ChEBI] synonym: "poisonous agents" RELATED [ChEBI] synonym: "poisonous substance" RELATED [ChEBI] synonym: "poisonous substances" RELATED [ChEBI] synonym: "poisons" RELATED [ChEBI] synonym: "toxic agent" RELATED [ChEBI] synonym: "toxic agents" RELATED [ChEBI] synonym: "toxic substance" RELATED [ChEBI] synonym: "toxic substances" RELATED [ChEBI] xref: Wikipedia:Poison is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:65212 name: polysaccharide derivative def: "A carbohydrate derivative that is any derivative of a polysaccharide." [] subset: 3_STAR synonym: "polysaccharide derivatives" RELATED [ChEBI] is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:18154 ! polysaccharide [Term] id: CHEBI:65255 name: food preservative def: "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." [] subset: 3_STAR synonym: "food preservatives" RELATED [ChEBI] is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:65256 name: antimicrobial food preservative def: "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." [] subset: 3_STAR synonym: "antimicrobial food preservatives" RELATED [ChEBI] synonym: "antimicrobial preservative" RELATED [ChEBI] synonym: "antimicrobial preservatives" RELATED [ChEBI] is_a: CHEBI:33281 ! antimicrobial agent is_a: CHEBI:65255 ! food preservative [Term] id: CHEBI:65296 name: primary ammonium ion def: "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." [] subset: 3_STAR synonym: "a primary amine" RELATED [UniProt] synonym: "substituted ammonium" RELATED [ChEBI] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:50994 ! primary amino compound [Term] id: CHEBI:67079 name: anti-inflammatory agent def: "Any compound that has anti-inflammatory effects." [] subset: 3_STAR synonym: "anti-inflammatory agents" RELATED [ChEBI] synonym: "antiinflammatory agent" RELATED [ChEBI] synonym: "antiinflammatory agents" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:72587 name: (R)-noradrenaline(1+) def: "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." [] subset: 3_STAR synonym: "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "(R)-noradrenaline" RELATED [UniProt] synonym: "(R)-noradrenaline cation" RELATED [ChEBI] synonym: "(R)-noradrenalinium cation" RELATED [ChEBI] synonym: "(R)-noradrenalinium(1+)" RELATED [ChEBI] xref: PDBeChem:E5E is_a: BFO:0000004 ! independent continuant is_a: CHEBI:166902 ! noradrenaline(1+) relationship: is_conjugate_acid_of CHEBI:18357 ! (R)-noradrenaline relationship: RO:0000087 CHEBI:77746 ! has role human metabolite [Term] id: CHEBI:72695 name: organic molecule def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." [] subset: 3_STAR synonym: "organic compound" RELATED [ChEBI] synonym: "organic compounds" RELATED [ChEBI] synonym: "organic molecules" RELATED [ChEBI] is_a: CHEBI:25367 ! molecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:72813 name: exopolysaccharide def: "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." [] subset: 3_STAR synonym: "exopolysaccharides" RELATED [ChEBI] synonym: "extracellular polymeric substance" RELATED [ChEBI] synonym: "extracellular polymeric substances" RELATED [ChEBI] xref: MetaCyc:Exopolysaccharides xref: PMID:11160795 {source="Europe PMC"} xref: PMID:11785425 {source="Europe PMC"} xref: PMID:1444258 {source="Europe PMC"} xref: PMID:15738217 {source="Europe PMC"} xref: PMID:16075348 {source="Europe PMC"} xref: PMID:17440912 {source="Europe PMC"} xref: PMID:18097339 {source="Europe PMC"} xref: PMID:19453747 {source="Europe PMC"} xref: PMID:20172021 {source="Europe PMC"} xref: PMID:20631870 {source="Europe PMC"} xref: PMID:20718297 {source="Europe PMC"} xref: PMID:2688547 {source="Europe PMC"} xref: PMID:6354590 {source="Europe PMC"} xref: Wikipedia:Exopolysaccharide xref: Wikipedia:Extracellular_polymeric_substance is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:73398 name: indole skeleton def: "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." [] subset: 3_STAR is_a: CHEBI:73541 ! organic heterobicyclic ring [Term] id: CHEBI:73541 name: organic heterobicyclic ring def: "A bicyclic organic group that contains both carbon and hetero atoms." [] subset: 3_STAR synonym: "organic heterobicyclic rings" RELATED [ChEBI] is_a: CHEBI:52845 ! cyclic organic group [Term] id: CHEBI:75763 name: eukaryotic metabolite def: "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." [] subset: 3_STAR synonym: "eukaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:75767 name: animal metabolite alt_id: CHEBI:77721 alt_id: CHEBI:77743 def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." [] subset: 3_STAR synonym: "animal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:75768 name: mammalian metabolite alt_id: CHEBI:77464 alt_id: CHEBI:77744 def: "Any animal metabolite produced during a metabolic reaction in mammals." [] subset: 3_STAR synonym: "mammalian metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:75771 name: mouse metabolite def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." [] subset: 3_STAR synonym: "mouse metabolites" RELATED [ChEBI] synonym: "Mus musculus metabolite" RELATED [ChEBI] synonym: "Mus musculus metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:75772 name: Saccharomyces cerevisiae metabolite alt_id: CHEBI:76949 alt_id: CHEBI:76951 def: "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." [] subset: 3_STAR synonym: "baker's yeast metabolite" RELATED [ChEBI] synonym: "baker's yeast metabolites" RELATED [ChEBI] synonym: "baker's yeast secondary metabolite" RELATED [ChEBI] synonym: "baker's yeast secondary metabolites" RELATED [ChEBI] synonym: "S. cerevisiae metabolite" RELATED [ChEBI] synonym: "S. cerevisiae metabolites" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolite" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae secondary metabolites" RELATED [ChEBI] is_a: CHEBI:76946 ! fungal metabolite [Term] id: CHEBI:75787 name: prokaryotic metabolite def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." [] subset: 3_STAR synonym: "prokaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76206 name: xenobiotic metabolite def: "Any metabolite produced by metabolism of a xenobiotic compound." [] subset: 3_STAR synonym: "xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76413 name: greenhouse gas def: "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." [] subset: 3_STAR synonym: "greenhouse gases" RELATED [ChEBI] xref: Wikipedia:Greenhouse_gas is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:76759 name: EC 3.* (hydrolase) inhibitor def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." [] subset: 3_STAR synonym: "EC 3.* (hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.* inhibitor" RELATED [ChEBI] synonym: "EC 3.* inhibitors" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitor" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitors" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitor" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitors" RELATED [ChEBI] synonym: "hydrolase inhibitor" RELATED [ChEBI] synonym: "hydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Hydrolase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:76764 name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." [] subset: 3_STAR synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* inhibitors" RELATED [ChEBI] is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor [Term] id: CHEBI:76807 name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." [] subset: 3_STAR synonym: "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitors" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor [Term] id: CHEBI:76924 name: plant metabolite alt_id: CHEBI:75766 alt_id: CHEBI:76925 def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." [] subset: 3_STAR synonym: "plant metabolites" RELATED [ChEBI] synonym: "plant secondary metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76946 name: fungal metabolite alt_id: CHEBI:75765 alt_id: CHEBI:76947 def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." [] subset: 3_STAR synonym: "fungal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76967 name: human xenobiotic metabolite def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." [] subset: 3_STAR synonym: "human xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:76206 ! xenobiotic metabolite is_a: CHEBI:77746 ! human metabolite [Term] id: CHEBI:76969 name: bacterial metabolite alt_id: CHEBI:75760 alt_id: CHEBI:76970 def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." [] subset: 3_STAR is_a: CHEBI:75787 ! prokaryotic metabolite [Term] id: CHEBI:76971 name: Escherichia coli metabolite def: "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." [] subset: 3_STAR synonym: "E.coli metabolite" RELATED [ChEBI] synonym: "E.coli metabolites" RELATED [ChEBI] synonym: "Escherichia coli metabolites" RELATED [ChEBI] is_a: CHEBI:76969 ! bacterial metabolite [Term] id: CHEBI:77746 name: human metabolite alt_id: CHEBI:75770 alt_id: CHEBI:77123 def: "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." [] subset: 3_STAR synonym: "H. sapiens metabolite" RELATED [ChEBI] synonym: "H. sapiens metabolites" RELATED [ChEBI] synonym: "Homo sapiens metabolite" RELATED [ChEBI] synonym: "Homo sapiens metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:77941 name: EC 3.5.1.4 (amidase) inhibitor def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." [] subset: 3_STAR synonym: "acylamidase inhibitor" RELATED [ChEBI] synonym: "acylamidase inhibitors" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitor" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitors" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitor" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitors" RELATED [ChEBI] synonym: "amidase inhibitor" RELATED [ChEBI] synonym: "amidase inhibitors" RELATED [ChEBI] synonym: "amidohydrolase inhibitor" RELATED [ChEBI] synonym: "amidohydrolase inhibitors" RELATED [ChEBI] synonym: "deaminase inhibitor" RELATED [ChEBI] synonym: "deaminase inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 (amidase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitors" RELATED [ChEBI] synonym: "fatty acylamidase inhibitor" RELATED [ChEBI] synonym: "fatty acylamidase inhibitors" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitor" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Amidase is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor [Term] id: CHEBI:77974 name: food packaging gas def: "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." [] subset: 3_STAR synonym: "food packaging gases" RELATED [ChEBI] xref: Wikipedia:Packaging_gas is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:78295 name: food component def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." [] subset: 3_STAR synonym: "dietary component" RELATED [ChEBI] synonym: "dietary components" RELATED [ChEBI] synonym: "food components" RELATED [ChEBI] is_a: CHEBI:52211 ! physiological role [Term] id: CHEBI:78433 name: refrigerant def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." [] subset: 3_STAR synonym: "refrigerants" RELATED [ChEBI] xref: Wikipedia:Refrigerant is_a: CHEBI:33232 ! application [Term] id: CHEBI:78608 name: alpha-amino-acid zwitterion alt_id: CHEBI:83409 def: "An amino acid-zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." [] subset: 3_STAR synonym: "alpha-amino acid zwitterion" RELATED [ChEBI] synonym: "alpha-amino acid zwitterions" RELATED [ChEBI] synonym: "alpha-amino-acid zwitterions" RELATED [ChEBI] synonym: "an alpha-amino acid" RELATED [UniProt] xref: MetaCyc:Alpha-Amino-Acids {source="SUBMITTER"} is_a: CHEBI:35238 ! amino-acid zwitterion relationship: is_tautomer_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:78616 name: carbohydrates and carbohydrate derivatives def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." [] subset: 3_STAR synonym: "carbohydrates and derivatives" RELATED [ChEBI] synonym: "carbohydrates and their derivatives" RELATED [ChEBI] is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:78675 name: fundamental metabolite def: "Any metabolite produced by all living cells." [] subset: 3_STAR synonym: "essential metabolite" RELATED [ChEBI] synonym: "essential metabolites" RELATED [ChEBI] synonym: "fundamental metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:79388 name: divalent inorganic anion def: "Any inorganic anion with a valency of two." [] subset: 3_STAR synonym: "divalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79389 name: monovalent inorganic anion def: "Any inorganic anion with a valency of one." [] subset: 3_STAR synonym: "monovalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:83039 name: crustacean metabolite def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." [] subset: 3_STAR synonym: "crustacean metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:83056 name: Daphnia magna metabolite def: "A Daphnia metabolite produced by the species Daphnia magna." [] subset: 3_STAR synonym: "Daphnia magna metabolites" RELATED [ChEBI] is_a: CHEBI:83057 ! Daphnia metabolite [Term] id: CHEBI:83057 name: Daphnia metabolite def: "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" [] subset: 3_STAR synonym: "Daphnia metabolites" RELATED [ChEBI] xref: Wikipedia:Daphnia is_a: CHEBI:83039 ! crustacean metabolite [Term] id: CHEBI:84729 name: hydroxyindoles def: "Any member of the class of indoles carrying at least one hydroxy group." [] subset: 3_STAR is_a: CHEBI:24828 ! indoles is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:68646 xref: GO:0005623 xref: KUPO:0000002 xref: MESH:D002477 xref: VHOG:0001533 xref: WBbt:0004017 xref: XAO:0003012 xref: ZFA:0009000 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: UBERON:0000061 ! anatomical structure disjoint_from: GO:0031012 ! extracellular matrix disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle relationship: has_part GO:0005634 {gci_filler="PATO:0001407", gci_relation="RO:0000053"} ! nucleus relationship: has_part GO:0005634 {gci_filler="PATO:0001908", gci_relation="RO:0000053"} ! nucleus relationship: in_taxon NCBITaxon:131567 ! cellular organisms property_value: editor_note "CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc." xsd:string property_value: editor_note "We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism." xsd:string property_value: IAO:0000111 "cell" xsd:string property_value: IAO:0000112 "PMID:18089833.Cancer Res. 2007 Dec 15;67(24):12018-25. \"...Epithelial cells were harvested from histologically confirmed adenocarcinomas ..\"" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/cl.owl [Term] id: CL:0000005 name: neural crest derived fibroblast def: "Any fibroblast that is derived from the neural crest." [https://orcid.org/0000-0001-5208-3432] synonym: "fibroblast neural crest derived" EXACT [] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000006 name: neuronal receptor cell def: "Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception." [FBC:Autogenerated] subset: cellxgene_subset synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] xref: ZFA:0009001 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000007 name: early embryonic cell (metazoa) def: "A cell found in the embryo before the formation of all the gem layers is complete." [GOC:tfm] xref: ZFA:0009002 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002321 ! embryonic cell (metazoa) [Term] id: CL:0000008 name: migratory cranial neural crest cell def: "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007091] xref: ZFA:0007091 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000011 name: migratory trunk neural crest cell def: "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007095] xref: ZFA:0007095 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000014 name: germ line stem cell def: "A stem cell that is the precursor of gametes." [doi:10.1016/j.stem.2012.05.016] synonym: "germline stem cell" EXACT [] xref: FBbt:00004861 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: ZFA:0005956 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000034 {is_inferred="true"} ! stem cell is_a: CL:0000039 ! germ line cell intersection_of: CL:0000039 ! germ line cell intersection_of: capable_of GO:0017145 ! stem cell division [Term] id: CL:0000015 name: male germ cell def: "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis." [https://orcid.org/0000-0001-5208-3432, PMID:29462262] subset: cellxgene_subset xref: FMA:72290 xref: MA:0002765 xref: ncithesaurus:Spermatogenic_Cell xref: VHOG:0001531 is_a: CL:0000586 {is_inferred="true"} ! germ cell relationship: capable_of_part_of GO:0007283 ! spermatogenesis property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000015" xsd:string {name="male germ cell on CELLxGENE CellGuide"} property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/574" xsd:string [Term] id: CL:0000017 name: spermatocyte def: "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids." [GOC:tfm, MESH:D013090] subset: cellxgene_subset xref: BTO:0001275 xref: CALOHA:TS-0951 xref: EMAPA:31484 xref: FBbt:00004936 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:84049 xref: WBbt:0006799 xref: ZFA:0009005 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000015 ! male germ cell intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0048137 ! spermatocyte division relationship: capable_of GO:0048137 ! spermatocyte division relationship: develops_from CL:0000020 ! spermatogonium [Term] id: CL:0000018 name: spermatid def: "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa." [MESH:D013087] subset: cellxgene_subset synonym: "nematoblast" EXACT [] xref: BTO:0001274 xref: CALOHA:TS-0950 xref: EMAPA:31486 xref: FBbt:00004942 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:72294 xref: WBbt:0006800 xref: ZFA:0005769 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000015 ! male germ cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000413 ! haploid cell intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0001675 ! acrosome assembly intersection_of: capable_of GO:0007288 ! sperm axoneme assembly intersection_of: capable_of GO:0007289 ! spermatid nucleus differentiation intersection_of: RO:0000053 PATO:0001375 ! bearer of haploid relationship: capable_of GO:0001675 ! acrosome assembly relationship: capable_of GO:0007288 ! sperm axoneme assembly relationship: capable_of GO:0007289 ! spermatid nucleus differentiation relationship: develops_from CL:0000657 ! secondary spermatocyte [Term] id: CL:0000019 name: sperm def: "A mature male germ cell that develops from a spermatid." [GOC:tfm, MESH:D013094] synonym: "sperm cell" EXACT [] synonym: "spermatozoid" EXACT [] synonym: "spermatozoon" EXACT [] xref: BTO:0001277 xref: BTO:0002046 xref: CALOHA:TS-0949 xref: FBbt:00004954 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67338 xref: WBbt:0006798 xref: ZFA:0009006 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000408 {is_inferred="true"} ! male gamete relationship: develops_from CL:0000018 ! spermatid property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000019" xsd:string {name="sperm on CELLxGENE CellGuide"} [Term] id: CL:0000020 name: spermatogonium def: "An euploid male germ cell of an early stage of spermatogenesis." [MESH:D013093] subset: cellxgene_subset synonym: "spermatogonial cell" EXACT [] xref: BTO:0000958 xref: CALOHA:TS-2193 xref: EMAPA:31482 xref: FBbt:00004934 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FBbt:00004935 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:72291 xref: ZFA:0009007 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000015 ! male germ cell intersection_of: CL:0000015 ! male germ cell intersection_of: RO:0000053 PATO:0001394 ! bearer of diploid intersection_of: RO:0000053 PATO:0001501 ! bearer of immature relationship: RO:0000053 PATO:0001394 ! bearer of diploid relationship: RO:0000053 PATO:0001501 ! bearer of immature [Term] id: CL:0000021 name: female germ cell def: "Female germ cell is a germ cell that supports female gamete production." [GOC:tfm, PMID:11023867, PMID:20454446] subset: cellxgene_subset xref: MA:0000388 xref: ncithesaurus:Egg xref: VHOG:0001530 is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000586 {is_inferred="true"} ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: capable_of GO:0048477 ! oogenesis relationship: capable_of GO:0048477 ! oogenesis [Term] id: CL:0000022 name: female germ line stem cell def: "A stem cell that is the precursor of female gametes." [doi:10.1016/j.stem.2012.05.016] xref: FBbt:00004873 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: CL:0000014 {is_inferred="true"} ! germ line stem cell is_a: CL:0000021 {is_inferred="true"} ! female germ cell intersection_of: CL:0000021 ! female germ cell intersection_of: capable_of GO:0017145 ! stem cell division [Term] id: CL:0000023 name: oocyte def: "A female germ cell that has entered meiosis." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset synonym: "oogonium" RELATED [] xref: BTO:0000964 xref: CALOHA:TS-0711 xref: FBbt:00004886 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:18644 xref: MESH:D009865 xref: WBbt:0006797 xref: ZFA:0001109 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000021 {is_inferred="true"} ! female germ cell relationship: participates_in GO:0007143 ! female meiotic nuclear division [Term] id: CL:0000024 name: oogonial cell def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset xref: FMA:83673 xref: ZFA:0005878 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000021 {is_inferred="true"} ! female germ cell intersection_of: CL:0000021 ! female germ cell intersection_of: capable_of GO:0000278 ! mitotic cell cycle relationship: capable_of GO:0000278 ! mitotic cell cycle relationship: develops_from CL:0000670 ! primordial germ cell [Term] id: CL:0000025 name: egg cell def: "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." [GOC:tfm, ISBN:0721662544] synonym: "mature oocyte" EXACT [] synonym: "ovum" EXACT [] xref: BTO:0000369 xref: BTO:0003801 xref: CALOHA:TS-2191 xref: FBbt:00057012 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67343 xref: MESH:D010063 xref: ZFA:0001570 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000675 {is_inferred="true"} ! female gamete relationship: develops_from CL:0000023 ! oocyte relationship: participates_in GO:0007143 ! female meiotic nuclear division property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Egg_cell.svg" xsd:anyURI [Term] id: CL:0000027 name: smooth muscle cell neural crest derived def: "A smooth muscle cell derived from the neural crest." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000029 name: neural crest derived neuron def: "Any neuron that develops from some migratory neural crest cell." [FBC:Autogenerated] subset: cellxgene_subset synonym: "neuron neural crest derived" EXACT [] xref: ZFA:0009009 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000540 {is_inferred="true"} ! neuron intersection_of: CL:0000540 ! neuron intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0002676 ! neural crest derived neuroblast [Term] id: CL:0000030 name: glioblast def: "A non-terminally differentiated cell that develops form the neuroectoderm. Glioblast has the potential to differentiate into various types of glial cells, including astrocytes and oligodendrocytes." [PMID:37824650, Wikipedia:Glioblast] subset: cellxgene_subset xref: ZFA:0009010 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0011026 ! progenitor cell relationship: develops_from CL:0000133 ! neurectodermal cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000030" xsd:string {name="glioblast on CELLxGENE CellGuide"} [Term] id: CL:0000031 name: neuroblast (sensu Vertebrata) def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast] subset: cellxgene_subset synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 xref: ZFA:0009011 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0011026 ! progenitor cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] xref: CALOHA:TS-2086 xref: FMA:63368 xref: ZFA:0005957 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0017145 ! stem cell division relationship: capable_of GO:0017145 ! stem cell division relationship: in_taxon NCBITaxon:33208 ! Metazoa property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000034" xsd:string {name="stem cell on CELLxGENE CellGuide"} [Term] id: CL:0000035 name: single fate stem cell def: "A stem cell that self-renews as well as give rise to a single mature cell type." [GOC:tfm] synonym: "unipotent stem cell" EXACT [] synonym: "unipotential stem cell" EXACT [] xref: FMA:70569 xref: ZFA:0009013 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000723 ! somatic stem cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0017145 ! stem cell division intersection_of: RO:0000053 PATO:0001400 ! bearer of unipotent relationship: RO:0000053 PATO:0001400 ! bearer of unipotent property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000035" xsd:string {name="single fate stem cell on CELLxGENE CellGuide"} [Term] id: CL:0000036 name: epithelial fate stem cell def: "A somatic stem cell that is committed to an epithelial fate, possessing the capacity for self-renewal and the ability to differentiate into one or more distinct mature cell types of the epithelial lineage. This cell is crucial for the development, homeostasis, repair, and regeneration of epithelial tissues." [doi:/10.1038/sj.eye.6700575, PMID:17289566] subset: cellxgene_subset subset: human_reference_atlas synonym: "epithelial stem cell" EXACT [] is_a: CL:0000723 ! somatic stem cell intersection_of: CL:0000723 ! somatic stem cell intersection_of: capable_of GO:0030855 ! epithelial cell differentiation relationship: capable_of GO:0030855 ! epithelial cell differentiation property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000036" xsd:string {name="epithelial fate stem cell on CELLxGENE CellGuide"} [Term] id: CL:0000037 name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] synonym: "hemopoietic stem cell" EXACT [] synonym: "HSC" RELATED OMO:0003000 [] xref: BTO:0000725 xref: CALOHA:TS-0448 xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 xref: ZFA:0009014 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: capable_of GO:0048103 ! somatic stem cell division intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000566 ! angioblastic mesenchymal cell property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000037" xsd:string {name="hematopoietic stem cell on CELLxGENE CellGuide"} [Term] id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] synonym: "CFU-E" RELATED OMO:0003000 [] synonym: "colony forming unit erythroid" RELATED [] synonym: "erythroid stem cell" RELATED [] xref: BTO:0004911 xref: ZFA:0009015 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000038" xsd:string {name="erythroid progenitor cell on CELLxGENE CellGuide"} [Term] id: CL:0000039 name: germ line cell def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [GOC:tfm, ISBN:0721662544] comment: Originally this term had some plant germ line cell children. subset: general_cell_types_upper_slim subset: ubprop:upper_level xref: ZFA:0009016 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000000 ! cell relationship: capable_of GO:0022414 ! reproductive process [Term] id: CL:0000047 name: neural stem cell def: "An undifferentiated neural cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple central nervous system neuronal and glial cell types." [PMID:30639325] subset: cellxgene_subset synonym: "neuronal stem cell" EXACT [PMID:16305818] synonym: "NSC" EXACT [] xref: BTO:0002881 xref: CALOHA:TS-2360 xref: FMA:86684 xref: ZFA:0009019 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002319 ! neural cell relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000048 name: multi fate stem cell def: "A stem cell that can give rise to multiple lineages of cells." [GOC:add] synonym: "multi-fate stem cell" EXACT [] synonym: "multifate stem cell" EXACT [] synonym: "multipotent cell" EXACT [] synonym: "multipotent stem cell" EXACT [] xref: FMA:84789 xref: ZFA:0009020 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000034 ! stem cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0017145 ! stem cell division intersection_of: RO:0000053 PATO:0001402 ! bearer of multipotent relationship: RO:0000053 PATO:0001402 ! bearer of multipotent [Term] id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CMP" RELATED OMO:0003000 [ISBN:0878932437] synonym: "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437] synonym: "common myeloid precursor" EXACT [] synonym: "multipotential myeloid stem cell" RELATED [ISBN:0878932437] synonym: "myeloid stem cell" RELATED [ISBN:0878932437] synonym: "pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437] xref: BTO:0004730 xref: ZFA:0009021 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell disjoint_from: CL:0000050 ! megakaryocyte-erythroid progenitor cell disjoint_from: CL:0000051 ! common lymphoid progenitor property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000049" xsd:string {name="common myeloid progenitor on CELLxGENE CellGuide"} [Term] id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] synonym: "colony forming unit erythroid megakaryocyte" EXACT [] synonym: "Meg/E progenitor" EXACT [] synonym: "megakaryocyte/erythrocyte progenitor" EXACT [] synonym: "megakaryocyte/erythroid progenitor cell" EXACT [] synonym: "MEP" EXACT [] xref: ZFA:0009022 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: capable_of GO:0030219 ! megakaryocyte differentiation property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000050" xsd:string {name="megakaryocyte-erythroid progenitor cell on CELLxGENE CellGuide"} [Term] id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. subset: cellxgene_subset subset: human_reference_atlas synonym: "CLP" RELATED OMO:0003000 [] synonym: "committed lymphopoietic stem cell" RELATED [] synonym: "common lymphocyte precursor" EXACT [] synonym: "common lymphocyte progenitor" EXACT [] synonym: "common lymphoid precursor" EXACT [] synonym: "early lymphocyte progenitor" RELATED [] synonym: "ELP" RELATED OMO:0003000 [] synonym: "lymphoid stem cell" RELATED [] synonym: "lymphopoietic stem cell" RELATED [] xref: ZFA:0009023 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: capable_of GO:0030098 ! lymphocyte differentiation relationship: capable_of GO:0030098 ! lymphocyte differentiation property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000051" xsd:string {name="common lymphoid progenitor on CELLxGENE CellGuide"} [Term] id: CL:0000052 name: totipotent stem cell def: "A stem cell from which all cells of the body can form." [GOC:add, GOC:tfm] synonym: "totipotential stem cell" EXACT [] xref: FMA:84790 xref: MESH:D039901 xref: ZFA:0009024 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000723 ! somatic stem cell [Term] id: CL:0000056 name: myoblast def: "A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair." [GOC:tfm, MESH:D032446, PMID:21849021] subset: cellxgene_subset xref: BTO:0000222 xref: CALOHA:TS-0650 xref: FBbt:00005083 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:70335 xref: VHOG:0001529 xref: ZFA:0009025 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000680 ! muscle precursor cell [Term] id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000452 xref: CALOHA:TS-0362 xref: FMA:63877 xref: NCIT:C12482 xref: VHOG:0001482 xref: ZFA:0009026 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000499 ! stromal cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000058 name: chondroblast def: "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell." [GO_REF:0000034, GOC:tfm, ISBN:0618947256] subset: cellxgene_subset synonym: "chrondoplast" EXACT [] xref: BTO:0003607 xref: FMA:66783 xref: ZFA:0009027 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002320 ! connective tissue cell is_a: CL:0011026 ! progenitor cell relationship: develops_from CL:0007009 ! prechondroblast relationship: produces UBERON:0002418 ! cartilage tissue [Term] id: CL:0000059 name: ameloblast def: "Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell." [GO_REF:0000034, GOC:tfm, MESH:D000565] comment: non-encoded relationship from VSAO produces VSAO:0000066 synonym: "amelocyte" EXACT [] synonym: "enamel secreting cell" EXACT [] xref: BTO:0001663 xref: FMA:70576 is_a: CL:0000146 ! simple columnar epithelial cell is_a: CL:0002077 ! ecto-epithelial cell is_a: CL:1100001 ! secretory epithelial cell relationship: adjacent_to UBERON:0001763 ! odontogenic papilla relationship: capable_of GO:0097186 ! amelogenesis relationship: develops_from CL:0007000 ! preameloblast relationship: part_of UBERON:0005176 ! tooth enamel organ relationship: produces UBERON:0001752 ! enamel [Term] id: CL:0000060 name: odontoblast def: "Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell." [GO_REF:0000034, ISBN:0618947256] comment: legacy def: One of the cells forming the outer surface of dental pulp that produces tooth dentin. subset: cellxgene_subset xref: BTO:0001769 xref: CALOHA:TS-0696 xref: FMA:62999 xref: MESH:D009804 xref: ZFA:0009029 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000710 ! neurecto-epithelial cell is_a: CL:0002148 ! dental pulp cell relationship: develops_from CL:0007003 ! preodontoblast relationship: part_of UBERON:0005176 ! tooth enamel organ relationship: produces UBERON:0001751 ! dentine [Term] id: CL:0000064 name: ciliated cell def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] subset: cellxgene_subset xref: VHOG:0001532 xref: XAO:0000031 xref: ZFA:0009032 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: has_part GO:0005929 ! cilium relationship: has_part GO:0005929 ! cilium [Term] id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] xref: BTO:0000414 xref: CALOHA:TS-2026 xref: CARO:0000077 xref: FBbt:00000124 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:66768 xref: WBbt:0003672 xref: ZFA:0009034 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell disjoint_from: CL:0000738 ! leukocyte relationship: part_of UBERON:0000483 ! epithelium property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Epithelial_cells.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000067 name: ciliated epithelial cell def: "An epithelial cell that has a cilia." [GOC:tfm] subset: cellxgene_subset xref: FMA:70605 xref: ZFA:0009035 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000064 ! ciliated cell is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: has_part GO:0005929 ! cilium [Term] id: CL:0000068 name: duct epithelial cell def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432] subset: cellxgene_subset xref: ZFA:0009372 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000058 ! duct relationship: part_of UBERON:0000058 ! duct property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000068" xsd:string {name="duct epithelial cell on CELLxGENE CellGuide"} [Term] id: CL:0000069 name: branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell [Term] id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: ZFA:0009036 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002139 ! endothelial cell of vascular tree intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0004638 ! blood vessel endothelium property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000071" xsd:string {name="blood vessel endothelial cell on CELLxGENE CellGuide"} [Term] id: CL:0000072 name: non-branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002078 ! meso-epithelial cell [Term] id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] subset: cellxgene_subset subset: human_reference_atlas xref: ZFA:0009038 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell subset: cellxgene_subset xref: CALOHA:TS-1249 xref: ZFA:0009039 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell [Term] id: CL:0000077 name: mesothelial cell def: "A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement." [GOC:tfm, ISBN:0721662544, PMID:26106328] comment: Mesothelial cells, which morphologically resemble squamous epithelial cells, express both epithelial markers (cytokeratins) and mesenchymal markers (vimentin), reflecting their mesodermal origin. They feature surface microvilli and apical-basal polarity. Under certain conditions, they can undergo mesothelial-to-mesenchymal transition. These cells also produce extracellular matrix proteins, maintain serosal homeostasis, and facilitate fluid transport. {xref="PMID:26106328"} subset: cellxgene_subset subset: human_reference_atlas synonym: "mesotheliocyte" EXACT [] xref: FMA:66773 xref: ZFA:0009040 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002078 ! meso-epithelial cell relationship: part_of UBERON:0001136 ! mesothelium property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000077" xsd:string {name="mesothelial cell on CELLxGENE CellGuide"} [Term] id: CL:0000078 name: peridermal cell def: "Any squamous epithelial cell that is part of some periderm." [FBC:Autogenerated] subset: cellxgene_subset xref: ZFA:0009041 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0000362 ! epidermal cell intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0003055 ! periderm relationship: part_of UBERON:0003055 ! periderm [Term] id: CL:0000080 name: circulating cell def: "A cell which moves among different tissues of the body, via blood, lymph, or other medium." [GOC:add] xref: ZFA:0009043 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000179 ! haemolymphatic fluid relationship: part_of UBERON:0000179 ! haemolymphatic fluid [Term] id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] subset: cellxgene_subset xref: FMA:62844 xref: MESH:D001773 xref: ZFA:0009044 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0008015 ! blood circulation relationship: capable_of GO:0008015 ! blood circulation [Term] id: CL:0000082 name: epithelial cell of lung def: "An epithelial cell of the lung." [https://orcid.org/0000-0001-5208-3432] subset: cellxgene_subset synonym: "lung epithelial cell" EXACT [] xref: BTO:0004299 is_a: CL:0002632 ! epithelial cell of lower respiratory tract intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000115 ! lung epithelium relationship: part_of UBERON:0000115 ! lung epithelium [Term] id: CL:0000083 name: epithelial cell of pancreas def: "An epithelial cell of the pancreas." [GOC:tfm] subset: cellxgene_subset synonym: "pancreas epithelial cell" EXACT [] synonym: "pancreatic epithelial cell" EXACT [] xref: BTO:0000028 xref: ZFA:0009045 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0001264 ! pancreas [Term] id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] subset: cellxgene_subset subset: human_reference_atlas synonym: "immature T cell" RELATED [] synonym: "mature T cell" RELATED [] synonym: "T lymphocyte" EXACT [] synonym: "T-cell" EXACT [] synonym: "T-lymphocyte" EXACT [] xref: BTO:0000782 xref: CALOHA:TS-1001 xref: FMA:62870 xref: MESH:D013601 xref: VHOG:0001479 xref: ZFA:0009046 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000542 {is_inferred="true"} ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: capable_of GO:0002456 ! T cell mediated immunity relationship: capable_of GO:0002456 ! T cell mediated immunity relationship: develops_from CL:0000827 ! pro-T cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000095 name: neuron associated cell subset: cellxgene_subset is_a: CL:0002319 ! neural cell relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000098 name: sensory epithelial cell def: "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] comment: The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710). synonym: "neuroepithelial cell" BROAD [] xref: BTO:0004301 xref: ZFA:0009050 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000099 name: interneuron def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395] subset: cellxgene_subset subset: human_reference_atlas synonym: "CNS interneuron" RELATED [] xref: BTO:0003811 xref: FBbt:00005125 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67313 xref: WBbt:0005113 xref: ZFA:0009051 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:2000029 ! central nervous system neuron relationship: part_of UBERON:0001017 ! central nervous system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000100 name: motor neuron def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686] subset: cellxgene_subset subset: human_reference_atlas synonym: "motoneuron" EXACT [] xref: BTO:0000312 xref: FBbt:00005123 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83617 xref: WBbt:0005409 xref: ZFA:0009052 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000527 ! efferent neuron property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000100" xsd:string {name="motor neuron on CELLxGENE CellGuide"} [Term] id: CL:0000101 name: sensory neuron def: "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." [ISBN:0721662544] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001037 xref: FBbt:00005124 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:84649 xref: MESH:D011984 xref: WBbt:0005759 xref: ZFA:0009053 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000526 ! afferent neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000107 name: autonomic neuron def: "A neuron whose cell body is within an autonomic ganglion." [GOC:tfm] xref: FMA:80121 xref: ZFA:0009059 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0002410 ! has soma location autonomic nervous system relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: RO:0002100 UBERON:0002410 ! has soma location autonomic nervous system [Term] id: CL:0000108 name: cholinergic neuron def: "A neuron that uses acetylcholine as a vesicular neurotransmitter." [GOC:tfm] subset: human_reference_atlas xref: BTO:0004902 xref: FBbt:00007173 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:84796 xref: MESH:D059329 xref: WBbt:0006840 xref: ZFA:0009060 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission relationship: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001433 xref: ZFA:0009064 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) is_a: CL:0000842 ! mononuclear leukocyte intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata) intersection_of: RO:0000053 PATO:0001407 ! bearer of mononucleate property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000113" xsd:string {name="mononuclear phagocyte on CELLxGENE CellGuide"} [Term] id: CL:0000114 name: surface ectodermal cell def: "An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024)." [doi:/10.1101/2024.07.02.601324, PMID:7892198, Wikipedia:Surface_ectoderm] synonym: "cell of surface ectoderm" EXACT [] synonym: "surface ectoderm cell" EXACT [doi:/10.1101/2024.07.02.601324] xref: FMA:72552 is_a: CL:0000221 ! ectodermal cell intersection_of: CL:0000221 ! ectodermal cell intersection_of: part_of UBERON:0000076 ! external ectoderm relationship: part_of UBERON:0000076 ! external ectoderm property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000114" xsd:string {name="surface ectodermal cell on CELLxGENE CellGuide"} [Term] id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 xref: CALOHA:TS-0278 xref: FMA:66772 xref: ZFA:0009065 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell relationship: develops_from CL:0000222 ! mesodermal cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000123 name: neuron associated cell (sensu Vertebrata) subset: cellxgene_subset is_a: CL:0000095 ! neuron associated cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 subset: cellxgene_subset subset: human_reference_atlas synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] xref: BTO:0002606 xref: CALOHA:TS-0415 xref: FBbt:00005144 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:54536 xref: ZFA:0009073 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000095 ! neuron associated cell property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000125" xsd:string {name="glial cell on CELLxGENE CellGuide"} [Term] id: CL:0000126 name: macroglial cell def: "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset synonym: "macroglia" RELATED OMO:0003004 [doi:10.1152/physrev.2001.81.2.871] synonym: "macrogliocyte" EXACT [] xref: BTO:0000771 xref: CALOHA:TS-2027 xref: FMA:54538 xref: ZFA:0009074 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000125 ! glial cell relationship: develops_from CL:0000339 ! glioblast (sensu Vertebrata) [Term] id: CL:0000128 name: oligodendrocyte def: "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system." [http://en.wikipedia.org/wiki/Oligodendrocyte, MESH:D009836] comment: Oligodendrocytes are reportedly MDP-positive and CD4-negative. subset: cellxgene_subset subset: human_reference_atlas synonym: "oligodendroglia" RELATED [] synonym: "OLs" EXACT [PMID:8734446] xref: BTO:0000962 xref: CALOHA:TS-0709 xref: FMA:54540 xref: ZFA:0009076 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000126 {is_inferred="true"} ! macroglial cell is_a: CL:4023154 ! myelinating glial cell relationship: develops_from CL:0002453 ! oligodendrocyte precursor cell relationship: part_of UBERON:0001017 ! central nervous system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000131 name: gut endothelial cell def: "An endothelial cell that lines the blood and lymphatic vessels of the digestive tract. This cell forms the gut–vascular barrier (GVB) through tight junctions and crosstalk with pericytes and enteric glial cells, regulating the passage of nutrients and immune cells while restricting microbial translocation into the bloodstream." [PMID:26564856] subset: cellxgene_subset xref: ZFA:0009078 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001555 ! digestive tract relationship: develops_from CL:0000223 ! endodermal cell relationship: part_of UBERON:0001555 ! digestive tract property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000131" xsd:string {name="gut endothelial cell on CELLxGENE CellGuide"} [Term] id: CL:0000133 name: neurectodermal cell def: "Ectoderm destined to be nervous tissue." [GOC:tfm, ISBN:068340007X] subset: cellxgene_subset synonym: "neurectoderm cell" EXACT [] xref: ZFA:0009080 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000221 ! ectodermal cell [Term] id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] synonym: "colony-forming unit-fibroblast" NARROW [] synonym: "marrow stromal cells" NARROW [PMID:11378515] synonym: "mesenchymal precursor cell" RELATED [] synonym: "mesenchymal progenitor cells" RELATED OMO:0003004 [MESH:D044982] synonym: "mesenchymal stem cell" RELATED [] synonym: "mesenchymal stromal cell" RELATED [] synonym: "mesenchymal stromal cells" RELATED OMO:0003004 [] synonym: "MSC" RELATED OMO:0003000 [PMID:11378515] synonym: "stem cells, mesenchymal" RELATED OMO:0003004 [MESH:D044982] xref: BTO:0002625 xref: BTO:0003298 xref: FMA:70546 xref: ZFA:0009081 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002320 {is_inferred="true"} ! connective tissue cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000134" xsd:string {name="mesenchymal stem cell on CELLxGENE CellGuide"} property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/474" xsd:string [Term] id: CL:0000136 name: adipocyte def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667] subset: cellxgene_subset subset: human_reference_atlas synonym: "adipose cell" EXACT [] synonym: "fat cell" EXACT [] xref: BTO:0000443 xref: CALOHA:TS-0012 xref: FMA:63880 xref: ZFA:0009082 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000325 ! stuff accumulating cell is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000136" xsd:string {name="adipocyte on CELLxGENE CellGuide"} [Term] id: CL:0000138 name: chondrocyte def: "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." [GO_REF:0000034, MESH:D019902] subset: cellxgene_subset synonym: "cartilage cell" EXACT [] xref: BTO:0000249 xref: CALOHA:TS-0138 xref: FMA:66782 xref: ZFA:0009084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000153 ! glycosaminoglycan secreting cell is_a: CL:0000667 ! collagen secreting cell relationship: develops_from CL:0000058 ! chondroblast relationship: located_in UBERON:0002418 ! cartilage tissue [Term] id: CL:0000145 name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "APC" RELATED OMO:0003000 [] xref: ZFA:0009088 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000145" xsd:string {name="professional antigen presenting cell on CELLxGENE CellGuide"} [Term] id: CL:0000146 name: simple columnar epithelial cell subset: human_reference_atlas xref: ZFA:0009089 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000075 ! columnar/cuboidal epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000147 name: pigment cell def: "A pigment cell is a cell that contains pigment granules." [GOC:tfm] synonym: "chromatocyte" EXACT [] synonym: "chromatophore" EXACT [] xref: VHOG:0001678 xref: ZFA:0009090 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000149 name: visual pigment cell synonym: "pigment cell" BROAD [] is_a: CL:0000147 ! pigment cell [Term] id: CL:0000150 name: glandular secretory epithelial cell def: "An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous." [GOC:tfm, ORCID:0000-0002-7073-9172] subset: cellxgene_subset synonym: "glandular epithelial cell" EXACT [] xref: CALOHA:TS-2085 xref: FMA:86494 is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002530 ! gland relationship: part_of UBERON:0002530 ! gland [Term] id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0032940 ! secretion by cell relationship: capable_of GO:0032940 ! secretion by cell [Term] id: CL:0000152 name: exocrine cell def: "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct." [ISBN:0198547684] subset: cellxgene_subset xref: FMA:16014 xref: ZFA:0009092 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000151 ! secretory cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002365 ! exocrine gland relationship: part_of UBERON:0002365 ! exocrine gland [Term] id: CL:0000153 name: glycosaminoglycan secreting cell def: "A cell that secretes glycosaminoglycans." [GOC:tfm] synonym: "GAG secreting cell" EXACT [] synonym: "hyaluronic acid secreting cell" NARROW [] xref: ZFA:0009093 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000327 ! extracellular matrix secreting cell is_a: CL:0000447 ! carbohydrate secreting cell [Term] id: CL:0000154 name: protein secreting cell def: "Any secretory cell that is capable of some protein secretion." [FBC:Autogenerated] is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0009306 ! protein secretion relationship: capable_of GO:0009306 ! protein secretion [Term] id: CL:0000159 name: seromucus secreting cell subset: cellxgene_subset is_a: CL:0000151 ! secretory cell [Term] id: CL:0000163 name: endocrine cell def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098] subset: cellxgene_subset subset: human_reference_atlas synonym: "endocrinocyte" EXACT [] xref: FMA:83809 xref: ZFA:0009096 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000151 ! secretory cell is_a: CL:0000164 {gci_relation="part_of", gci_filler="UBERON:0000945"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0000160", gci_relation="part_of"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0001264", gci_relation="part_of"} ! enteroendocrine cell is_a: CL:0000255 ! eukaryotic cell relationship: part_of UBERON:0000949 ! endocrine system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000164 name: enteroendocrine cell def: "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [GOC:tfm, SANBI:mhl] subset: cellxgene_subset xref: BTO:0003865 xref: FMA:62930 xref: MESH:D019858 xref: ZFA:0009097 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000163 ! endocrine cell is_a: CL:1100001 ! secretory epithelial cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000164" xsd:string {name="enteroendocrine cell on CELLxGENE CellGuide"} [Term] id: CL:0000165 name: neuroendocrine cell def: "A neuron that is capable of some hormone secretion in response to neuronal signals." [MESH:D055099] comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. \n\nThe modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron. {xref="https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073", xref="PMID:5342440"} subset: cellxgene_subset subset: human_reference_atlas synonym: "neurosecretory cell" RELATED [] synonym: "neurosecretory neuron" RELATED [] xref: BTO:0002691 xref: FBbt:00005130 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83810 xref: ZFA:0009098 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000163 ! endocrine cell is_a: CL:0000527 ! efferent neuron is_a: CL:0000710 ! neurecto-epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0046879 ! hormone secretion property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000167 name: peptide hormone secreting cell def: "Any secretory cell that is capable of some peptide hormone secretion." [FBC:Autogenerated] xref: ZFA:0009100 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0030072 ! peptide hormone secretion relationship: capable_of GO:0030072 ! peptide hormone secretion [Term] id: CL:0000168 name: insulin secreting cell def: "Any secretory cell that is capable of some insulin secretion." [FBC:Autogenerated] xref: BTO:0000783 xref: ZFA:0009101 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000154 ! protein secreting cell is_a: CL:0000167 ! peptide hormone secreting cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0030073 ! insulin secretion relationship: capable_of GO:0030073 ! insulin secretion [Term] id: CL:0000169 name: type B pancreatic cell def: "A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, http://en.wikipedia.org/wiki/Pancreatic_b_cell, ISBN:0517223651] comment: Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression. subset: cellxgene_subset subset: human_reference_atlas synonym: "B-cell of pancreatic islet" EXACT [FMA:70586] synonym: "beta cell" BROAD [ZFA:0009102] synonym: "beta cell islet" RELATED [MA:0002419] synonym: "beta cell of pancreatic islet" EXACT [FMA:70586] synonym: "insulin-secreting cell" EXACT [FMA:70586] synonym: "pancreatic B cell" EXACT [] synonym: "pancreatic B-cell" EXACT [FMA:70586] synonym: "pancreatic beta cell" EXACT [FMA:70586] synonym: "pancreatic islet core" EXACT [MA:0002419] synonym: "type B enteroendocrine cell" EXACT [FMA:70586] xref: BTO:0000783 xref: EV:0200009 xref: FMA:70586 xref: MA:0002419 xref: ncithesaurus:Beta_Cell xref: ZFA:0009102 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000168 {is_inferred="true"} ! insulin secreting cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: capable_of GO:0030073 ! insulin secretion intersection_of: part_of UBERON:0000006 ! islet of Langerhans relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000169" xsd:string {name="type B pancreatic cell on CELLxGENE CellGuide"} [Term] id: CL:0000170 name: glucagon secreting cell def: "A cell that secretes glucagon." [GOC:tfm] synonym: "glucagon-secreting cell" EXACT [] xref: FMA:84045 xref: ZFA:0009103 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070091 ! glucagon secretion relationship: capable_of GO:0070091 ! glucagon secretion [Term] id: CL:0000171 name: pancreatic A cell def: "A type A enteroendocrine cell found in the periphery of the islets of Langerhans that secretes glucagon." [GOC:tfm, ISBN:0721662544] subset: cellxgene_subset subset: human_reference_atlas synonym: "alpha cell of islet of Langerhans" EXACT [] synonym: "pancreatic alpha cell" EXACT [] xref: BTO:0000990 xref: FMA:70585 xref: MESH:D050416 xref: ZFA:0009104 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: part_of UBERON:0000006 ! islet of Langerhans relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000171" xsd:string {name="pancreatic A cell on CELLxGENE CellGuide"} [Term] id: CL:0000172 name: somatostatin secreting cell def: "Any secretory cell that is capable of some somatostatin secretion." [FBC:Autogenerated] xref: ZFA:0009105 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070253 ! somatostatin secretion relationship: capable_of GO:0070253 ! somatostatin secretion [Term] id: CL:0000173 name: pancreatic D cell def: "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." [FMA:0517223651, GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "D-cell of pancreatic islet" EXACT [] synonym: "delta cell of islet" EXACT [] synonym: "delta cell of pancreatic islet" EXACT [] synonym: "pancreatic D-cell" EXACT [] synonym: "pancreatic delta cell" EXACT [] synonym: "somatostatin-secreting pancreatic cell" EXACT [] xref: BTO:0000803 xref: FMA:70587 xref: ZFA:0005743 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000173" xsd:string {name="pancreatic D cell on CELLxGENE CellGuide"} [Term] id: CL:0000174 name: steroid hormone secreting cell def: "Any secretory cell that is capable of some steroid hormone secretion." [FBC:Autogenerated] xref: ZFA:0009106 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0035929 ! steroid hormone secretion relationship: capable_of GO:0035929 ! steroid hormone secretion [Term] id: CL:0000182 name: hepatocyte def: "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, http://en.wikipedia.org/wiki/Hepatocyte, ISBN:0412046911, MESH:D022781, PMID:19717280] comment: Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive. subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000575 xref: CALOHA:TS-0454 xref: FMA:14515 xref: ZFA:0009111 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell is_a: CL:0000417 ! endopolyploid cell relationship: capable_of GO:0006699 ! bile acid biosynthetic process relationship: capable_of GO:0098754 ! detoxification relationship: develops_from CL:0005026 ! hepatoblast relationship: part_of UBERON:0002107 ! liver property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000182" xsd:string {name="hepatocyte on CELLxGENE CellGuide"} [Term] id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 xref: BTO:0000902 xref: CALOHA:TS-2032 xref: FBbt:00005074 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67328 xref: WBbt:0003675 xref: ZFA:0009114 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000183 ! contractile cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000393 ! electrically responsive cell relationship: develops_from CL:0000056 ! myoblast property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI [Term] id: CL:0000188 name: cell of skeletal muscle def: "A somatic cell located in skeletal muscle." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "skeletal muscle cell" EXACT [] xref: BTO:0004392 xref: CALOHA:TS-2158 xref: FMA:9727 xref: ZFA:0009115 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: part_of UBERON:0001134 ! skeletal muscle tissue property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000188" xsd:string {name="cell of skeletal muscle on CELLxGENE CellGuide"} [Term] id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] subset: cellxgene_subset subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] synonym: "non-striated muscle cell" BROAD [] synonym: "SMCs" EXACT [PMID:9315361] synonym: "smooth muscle fiber" EXACT [] xref: BTO:0004576 xref: CALOHA:TS-2159 xref: FMA:14072 xref: ZFA:0009118 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0008000 ! non-striated muscle cell is_a: CL:0008007 ! visceral muscle cell relationship: develops_from CL:0000514 ! smooth muscle myoblast property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000192" xsd:string {name="smooth muscle cell on CELLxGENE CellGuide"} [Term] id: CL:0000197 name: sensory receptor cell def: "A cell that is capable of detection of a stimulus involved in sensory perception." [] synonym: "receptor cell" EXACT [] xref: MESH:D011984 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: part_of UBERON:0001032 ! sensory system relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: part_of UBERON:0001032 ! sensory system [Term] id: CL:0000199 name: mechanoreceptor cell def: "A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system." [MESH:D008465] synonym: "mechanoreceptor" RELATED [MP:0000972] xref: ZFA:0009120 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000101 ! sensory neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050974 ! detection of mechanical stimulus involved in sensory perception relationship: capable_of GO:0050974 ! detection of mechanical stimulus involved in sensory perception [Term] id: CL:0000200 name: touch receptor cell def: "Any neuron that is capable of some detection of mechanical stimulus involved in sensory perception of touch." [FBC:Autogenerated] is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000199 ! mechanoreceptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch relationship: capable_of GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch [Term] id: CL:0000206 name: chemoreceptor cell def: "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood." [MESH:D002628] xref: ZFA:0009124 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception relationship: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception [Term] id: CL:0000207 name: olfactory receptor cell def: "Any neuron that is capable of some detection of chemical stimulus involved in sensory perception of smell." [FBC:Autogenerated] subset: cellxgene_subset synonym: "odorant receptor cell" EXACT [] synonym: "olfactory receptor neuron" EXACT [] synonym: "olfactory sensory neuron" EXACT [] synonym: "Schultze's cell" EXACT [] xref: BTO:0004185 xref: FMA:67860 xref: MESH:D018034 xref: Wikipedia:Olfactory_receptor_neuron xref: ZFA:0009125 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000206 ! chemoreceptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: part_of UBERON:0005725 ! olfactory system [Term] id: CL:0000209 name: taste receptor cell def: "A specialized cell involved in gustatory sensory perception." [GOC:tfm, ISBN:0618947256] subset: cellxgene_subset synonym: "taste bud cell" EXACT [] xref: FMA:67910 xref: ZFA:0009126 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000098 ! sensory epithelial cell is_a: CL:0000206 ! chemoreceptor cell is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000206 ! chemoreceptor cell intersection_of: capable_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste relationship: capable_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000209" xsd:string {name="taste receptor cell on CELLxGENE CellGuide"} [Term] id: CL:0000210 name: photoreceptor cell def: "A cell specialized in detecting light stimuli that are involved in visual perception." [MESH:D010786] subset: cellxgene_subset xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FBbt:00004211 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86740 xref: ZFA:0009127 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000101 ! sensory neuron is_a: CL:0008028 ! visual system neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050908 ! detection of light stimulus involved in visual perception relationship: capable_of GO:0050908 ! detection of light stimulus involved in visual perception property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg" xsd:anyURI property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000210" xsd:string {name="photoreceptor cell on CELLxGENE CellGuide"} [Term] id: CL:0000211 name: electrically active cell def: "A cell whose function is determined by the generation or the reception of an electric signal." [FB:ma] xref: ZFA:0009128 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000000 ! cell [Term] id: CL:0000214 name: synovial cell def: "A cell located in the synovial joint." [] synonym: "synoviocyte" EXACT [] xref: CALOHA:TS-0995 xref: ZFA:0009131 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002078 {is_inferred="true"} ! meso-epithelial cell relationship: part_of UBERON:0002217 ! synovial joint [Term] id: CL:0000216 name: Sertoli cell def: "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:D012708] subset: cellxgene_subset xref: BTO:0001238 xref: CALOHA:TS-0922 xref: FMA:72298 xref: VHOG:0001348 xref: ZFA:0009133 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000511 ! androgen binding protein secreting cell is_a: CL:0000630 {is_inferred="true"} ! supporting cell is_a: CL:0002625 ! seminiferous tubule epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000630 ! supporting cell intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000216" xsd:string {name="Sertoli cell on CELLxGENE CellGuide"} [Term] id: CL:0000218 name: myelinating Schwann cell def: "A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons." [GOC:cvs, GOC:tfm, MESH:D012583] subset: cellxgene_subset synonym: "neurilemmal cell" EXACT [] synonym: "peripheral neuroglial cell" BROAD [] synonym: "Schwann cell" BROAD [] xref: CALOHA:TS-0898 xref: FMA:62121 xref: ZFA:0009135 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002573 ! Schwann cell is_a: CL:4023154 ! myelinating glial cell relationship: develops_from CL:0002377 ! immature Schwann cell [Term] id: CL:0000219 name: motile cell def: "A cell that moves by its own activities." [FB:ma] xref: ZFA:0009136 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0048870 ! cell motility relationship: capable_of GO:0048870 ! cell motility [Term] id: CL:0000221 name: ectodermal cell def: "A cell of the outer of the three germ layers of the embryo." [MESH:D004475] subset: cellxgene_subset synonym: "ectoderm cell" EXACT [] xref: FMA:72549 xref: ZFA:0009137 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000924 ! ectoderm [Term] id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 xref: ZFA:0009138 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000926 ! mesoderm property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000222" xsd:string {name="mesodermal cell on CELLxGENE CellGuide"} [Term] id: CL:0000223 name: endodermal cell def: "A cell of the inner of the three germ layers of the embryo." [MESH:D004707] synonym: "endoderm cell" EXACT [] xref: FMA:72555 xref: ZFA:0009139 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000925 ! endoderm [Term] id: CL:0000226 name: single nucleate cell def: "A cell with a single nucleus." [FB:ma, GOC:tfm] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001407 ! bearer of mononucleate relationship: RO:0000053 PATO:0001407 ! bearer of mononucleate [Term] id: CL:0000228 name: multinucleate cell def: "A cell with more than one nucleus." [FB:ma, Wikipedia:Multinucleate] synonym: "multinucleated cells" EXACT [Wikipedia:Multinucleate] synonym: "polynuclear cells" EXACT [Wikipedia:Multinucleate] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001908 ! bearer of multinucleate relationship: RO:0000053 PATO:0001908 ! bearer of multinucleate [Term] id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] xref: BTO:0000424 xref: CALOHA:TS-0290 xref: FMA:81100 is_a: CL:0000081 ! blood cell is_a: CL:0000329 ! oxygen accumulating cell is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0008015 ! blood circulation intersection_of: capable_of GO:0015671 ! oxygen transport intersection_of: CL:4030045 GO:0005840 ! lacks_part ribosome intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 intersection_of: RO:0000053 PATO:0002039 ! bearer of biconcave relationship: CL:4030045 GO:0005840 ! lacks_part ribosome relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: develops_from CL:0000558 ! reticulocyte relationship: RO:0000053 PATO:0002039 ! bearer of biconcave property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000232" xsd:string {name="erythrocyte on CELLxGENE CellGuide"} [Term] id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] subset: cellxgene_subset xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 xref: ZFA:0009140 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell is_a: CL:0000325 ! stuff accumulating cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0006909 ! phagocytosis relationship: capable_of GO:0006909 ! phagocytosis property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000234" xsd:string {name="phagocyte on CELLxGENE CellGuide"} [Term] id: CL:0000255 name: eukaryotic cell def: "Any cell that in taxon some Eukaryota." [FBC:Autogenerated] xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: in_taxon NCBITaxon:2759 ! Eukaryota relationship: in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: CL:0000287 name: eye photoreceptor cell def: "Any photoreceptor cell that is part of some eye." [FBC:Autogenerated] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas xref: ZFA:0009154 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000970 ! eye relationship: part_of UBERON:0000970 ! eye property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000287" xsd:string {name="eye photoreceptor cell on CELLxGENE CellGuide"} [Term] id: CL:0000300 name: gamete def: "A mature sexual reproductive cell having a single set of unpaired chromosomes." [GOC:tfm, ISBN:0721662544] synonym: "haploid germ cell" RELATED [] synonym: "haploid nucleated cell" EXACT [] xref: CALOHA:TS-0395 xref: FBbt:00005412 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:18649 xref: ZFA:0009156 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000413 ! haploid cell is_a: CL:0000586 {is_inferred="true"} ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: capable_of GO:0009566 ! fertilization intersection_of: RO:0000053 PATO:0001375 ! bearer of haploid relationship: capable_of GO:0009566 ! fertilization property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000300" xsd:string {name="gamete on CELLxGENE CellGuide"} [Term] id: CL:0000306 name: crystallin accumulating cell subset: eye_upper_slim synonym: "lens cell" EXACT [] is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000307 name: tracheal epithelial cell def: "An epithelial cell found in the trachea." [GOC:tfm] comment: This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell' synonym: "tracheocyte" EXACT [] xref: FMA:74793 is_a: CL:0002202 {is_inferred="true"} ! epithelial cell of tracheobronchial tree intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from CL:0000377 ! tracheoblast relationship: part_of UBERON:0003126 ! trachea [Term] id: CL:0000313 name: serous secreting cell def: "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] subset: cellxgene_subset synonym: "serous cell" EXACT [] xref: BTO:0003687 xref: FMA:62511 is_a: CL:0000159 ! seromucus secreting cell [Term] id: CL:0000319 name: mucus secreting cell def: "Any cell that is capable of some mucus secretion." [FBC:Autogenerated] subset: cellxgene_subset synonym: "mucous cell" EXACT [] xref: BTO:0003689 xref: ZFA:0009159 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000159 ! seromucus secreting cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0070254 ! mucus secretion relationship: capable_of GO:0070254 ! mucus secretion [Term] id: CL:0000325 name: stuff accumulating cell def: "A cell that is specialised to accumulate a particular substance(s)." [FB:ma] subset: ubprop:upper_level is_a: CL:0000000 ! cell [Term] id: CL:0000327 name: extracellular matrix secreting cell subset: cellxgene_subset xref: ZFA:0009162 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000499 ! stromal cell [Term] id: CL:0000329 name: oxygen accumulating cell def: "Any cell that is capable of some oxygen transport." [FBC:Autogenerated] xref: ZFA:0009164 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0015671 ! oxygen transport relationship: capable_of GO:0015671 ! oxygen transport [Term] id: CL:0000333 name: migratory neural crest cell def: "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." [doi:10.1016/j.stem.2015.02.017] xref: FMA:86667 xref: ZFA:0007086 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell relationship: develops_from CL:0007004 ! premigratory neural crest cell [Term] id: CL:0000335 name: mesenchyme condensation cell def: "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." [GOC:tfm, PMID:5025404] xref: ZFA:0009166 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0008019 ! mesenchymal cell [Term] id: CL:0000339 name: glioblast (sensu Vertebrata) def: "An early neural cell developing from the early ependymal cell of the neural tube." [GOC:tfm, ISBN:0618947256] synonym: "spongioblast" EXACT [] xref: FMA:70564 xref: ZFA:0009169 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000030 ! glioblast is_a: CL:0000123 ! neuron associated cell (sensu Vertebrata) [Term] id: CL:0000347 name: scleral cell def: "A cell of the sclera of the eye." [GOC:add] subset: eye_upper_slim xref: ZFA:0009174 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001773 ! sclera relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0001773 ! sclera [Term] id: CL:0000348 name: choroidal cell of the eye def: "A cell that is part of optic choroid." [GOC:add] subset: eye_upper_slim xref: ZFA:0009175 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001776 ! optic choroid relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0001776 ! optic choroid [Term] id: CL:0000349 name: extraembryonic cell def: "Any cell that is part of some extraembryonic structure." [FBC:Autogenerated] subset: cellxgene_subset subset: general_cell_types_upper_slim xref: ZFA:0009176 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000478 ! extraembryonic structure relationship: part_of UBERON:0000478 ! extraembryonic structure [Term] id: CL:0000351 name: trophoblast cell def: "An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development." [doi:10.1007/978-3-030-84725-8, GOC:tfm, MESH:D014327, PMID:37630754] synonym: "trophoblastic cell" EXACT [doi:10.1007/978-3-030-84725-8] xref: FMA:83028 is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell relationship: develops_from CL:1000274 ! trophectodermal cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000351" xsd:string {name="trophoblast cell on CELLxGENE CellGuide"} [Term] id: CL:0000352 name: epiblast cell def: "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation." [GOC:tfm, ISBN:0618947256] is_a: CL:0000052 ! totipotent stem cell [Term] id: CL:0000353 name: blastoderm cell def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." [MESH:D001756] synonym: "blastomere" EXACT [] xref: BTO:0001473 xref: FMA:72551 xref: ZFA:0009177 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000007 ! early embryonic cell (metazoa) [Term] id: CL:0000354 name: blastemal cell synonym: "blastema cell" EXACT [] xref: ncithesaurus:Blastemal_Cell xref: ZFA:0009178 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000048 ! multi fate stem cell [Term] id: CL:0000355 name: multi-potent skeletal muscle stem cell def: "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell." [PMID:18282570] comment: Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo. xref: FMA:86767 xref: ZFA:0009179 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: CL:0000188 ! cell of skeletal muscle intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue [Term] id: CL:0000358 name: sphincter associated smooth muscle cell def: "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [GOC:cjm] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0004590 ! sphincter muscle relationship: part_of UBERON:0004590 ! sphincter muscle property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000358" xsd:string {name="sphincter associated smooth muscle cell on CELLxGENE CellGuide"} [Term] id: CL:0000359 name: vascular associated smooth muscle cell def: "A smooth muscle cell associated with the vasculature." [GOC:dsd, GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "vascular smooth muscle cell" EXACT [] synonym: "VSMC" EXACT [] xref: ZFA:0009181 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:4033054 ! perivascular cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0002049 ! vasculature relationship: part_of UBERON:0002049 ! vasculature property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000359" xsd:string {name="vascular associated smooth muscle cell on CELLxGENE CellGuide"} [Term] id: CL:0000362 name: epidermal cell def: "An epithelial cell of the integument (the outer layer of an organism)." [Flybase:dsj, MA:ma] subset: cellxgene_subset synonym: "cell of epidermis" EXACT [FMA:62411] synonym: "epithelial cell of skin" NARROW [FMA:62411] xref: BTO:0001470 xref: CALOHA:TS-0283 xref: FMA:62411 xref: MESH:D000078404 xref: ZFA:0009183 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0007376 ! outer epithelium relationship: part_of UBERON:0007376 ! outer epithelium property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000362" xsd:string {name="epidermal cell on CELLxGENE CellGuide"} [Term] id: CL:0000365 name: animal zygote def: "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." [ISBN:0471245208] synonym: "zygote" BROAD [] xref: BTO:0000854 xref: EHDAA2:0004546 xref: FMA:72395 is_a: CL:0000007 ! early embryonic cell (metazoa) is_a: CL:0000255 ! eukaryotic cell is_a: CL:0010017 ! zygote intersection_of: CL:0010017 ! zygote intersection_of: in_taxon NCBITaxon:33208 ! Metazoa relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: CL:0000377 name: tracheoblast is_a: CL:0000069 ! branched duct epithelial cell [Term] id: CL:0000388 name: tendon cell def: "An elongated fibroblast that is part of a tendon. Its cytoplasm is stretched between the collagen fibres of the tendon, and it possesses a central nucleus with a prominent nucleolus. Tendon cell has a well-developed rough endoplasmic reticulum, and it is responsible for the synthesis and turnover of tendon fibres and ground substance." [GOC:NV, GOC:tfm, PMID:37894875, PMID:957445] subset: cellxgene_subset synonym: "muscle attachment cell" EXACT [] synonym: "tenocyte" RELATED [] xref: ZFA:0009189 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:1000307 ! fibroblast of dense regular elastic tissue intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000043 ! tendon relationship: part_of UBERON:0000043 ! tendon [Term] id: CL:0000393 name: electrically responsive cell def: "A cell whose function is determined by its response to an electric signal." [FB:ma] xref: ZFA:0009190 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000397 name: ganglion interneuron def: "Any interneuron that has its soma located in some ganglion." [FBC:Autogenerated] subset: cellxgene_subset is_a: CL:0000099 {is_inferred="true"} ! interneuron intersection_of: CL:0000099 ! interneuron intersection_of: RO:0002100 UBERON:0000045 ! has soma location ganglion relationship: RO:0002100 UBERON:0000045 ! has soma location ganglion property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000397" xsd:string {name="ganglion interneuron on CELLxGENE CellGuide"} [Term] id: CL:0000404 name: electrically signaling cell def: "A cell that initiates an electrical signal and passes that signal to another cell." [FB:ma] xref: ZFA:0009193 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000408 name: male gamete def: "Any male germ cell that has characteristic some haploid and is capable of some fertilization." [FBC:Autogenerated] xref: BTO:0001277 xref: CALOHA:TS-0949 is_a: CL:0000015 {is_inferred="true"} ! male germ cell is_a: CL:0000300 {is_inferred="true"} ! gamete intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0009566 ! fertilization intersection_of: RO:0000053 PATO:0001375 ! bearer of haploid property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000408" xsd:string {name="male gamete on CELLxGENE CellGuide"} [Term] id: CL:0000412 name: polyploid cell def: "A cell that contains more than two haploid sets of chromosomes." [FB:ma, https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy, PMID:32646579] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001377 ! bearer of polyploid relationship: RO:0000053 PATO:0001377 ! bearer of polyploid [Term] id: CL:0000413 name: haploid cell def: "A cell whose nucleus contains a single haploid genome." [FB:ma, GOC:tfm] is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0001375 ! bearer of haploid relationship: RO:0000053 PATO:0001375 ! bearer of haploid [Term] id: CL:0000417 name: endopolyploid cell is_a: CL:0000412 ! polyploid cell [Term] id: CL:0000447 name: carbohydrate secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] subset: cellxgene_subset subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] synonym: "veiled cell" RELATED [] xref: BTO:0002042 xref: CALOHA:TS-0194 xref: FMA:83036 xref: MESH:D003713 xref: ZFA:0009209 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000113 ! mononuclear phagocyte is_a: CL:0000145 ! professional antigen presenting cell intersection_of: CL:0000738 ! leukocyte intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: capable_of GO:0019882 ! antigen processing and presentation intersection_of: capable_of GO:0045580 ! regulation of T cell differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: has_part GO:0042613 ! MHC class II protein complex intersection_of: RO:0000053 PATO:0001407 ! bearer of mononucleate disjoint_from: CL:0000542 ! lymphocyte relationship: capable_of GO:0001816 ! cytokine production relationship: capable_of GO:0045580 ! regulation of T cell differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: has_part GO:0042613 ! MHC class II protein complex property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000451" xsd:string {name="dendritic cell on CELLxGENE CellGuide"} [Term] id: CL:0000457 name: biogenic amine secreting cell xref: ZFA:0009212 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000151 ! secretory cell [Term] id: CL:0000458 name: serotonin secreting cell def: "A cell type that secretes 5-Hydroxytryptamine (serotonin)." [GOC:tfm, PMID:19630576] synonym: "5-HT secreting cell" EXACT [] synonym: "5-Hydroxytryptamine secreting cell" EXACT [] xref: ZFA:0009213 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0001820 ! serotonin secretion relationship: capable_of GO:0001820 ! serotonin secretion [Term] id: CL:0000459 name: noradrenergic cell def: "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme." [GOC:tfm, ISBN:068340007X] subset: cellxgene_subset synonym: "noradrenaline secreting cell" EXACT [] synonym: "norepinephrin secreting cell" EXACT [] synonym: "norepinephrine secreting cell" EXACT [] xref: ZFA:0009214 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0048243 ! norepinephrine secretion relationship: capable_of GO:0048243 ! norepinephrine secretion [Term] id: CL:0000488 name: visible light photoreceptor cell def: "A photoreceptor cell that detects visible light." [GOC:tfm] xref: ZFA:0009219 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: capable_of GO:0009584 ! detection of visible light relationship: capable_of GO:0009584 ! detection of visible light [Term] id: CL:0000499 name: stromal cell def: "A connective tissue cell of an organ found in the loose connective tissue." [GOC:tfm, MESH:D017154] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0002064 xref: FMA:83624 xref: ZFA:0009226 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000499" xsd:string {name="stromal cell on CELLxGENE CellGuide"} [Term] id: CL:0000502 name: type D enteroendocrine cell def: "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:D019864] subset: cellxgene_subset synonym: "D cell" EXACT [] xref: FMA:62935 xref: ZFA:0009228 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0000172 ! somatostatin secreting cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000502" xsd:string {name="type D enteroendocrine cell on CELLxGENE CellGuide"} [Term] id: CL:0000506 name: enkephalin secreting cell def: "An endorphine cell that secretes enkephalin." [GO:tfm] xref: ZFA:0009231 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000507 ! endorphin secreting cell [Term] id: CL:0000507 name: endorphin secreting cell def: "A peptide hormone secreting cell that secretes endorphin." [GO:tfm] xref: ZFA:0009232 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000508 name: type G enteroendocrine cell def: "An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." [GOC:tfm, ISBN:0517223651, MESH:D019863, PMID:10700044, PMID:35674015, PMID:37240181] subset: cellxgene_subset synonym: "G cell" EXACT [] xref: BTO:0004108 xref: FMA:67609 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0000506 ! enkephalin secreting cell is_a: CL:0000509 ! gastrin secreting cell [Term] id: CL:0000509 name: gastrin secreting cell def: "A peptide hormone secreting cell that secretes gastrin." [GO:tfm] subset: human_reference_atlas is_a: CL:0000167 ! peptide hormone secreting cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000511 name: androgen binding protein secreting cell def: "A peptide hormone secreting cell that secretes androgen binding protein." [GO:tfm] is_a: CL:0000154 ! protein secreting cell [Term] id: CL:0000513 name: cardiac muscle myoblast def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386] subset: cellxgene_subset synonym: "cardiac muscle progenitor cell" EXACT [] synonym: "cardiomyocyte progenitor cell" EXACT [] xref: FMA:84797 xref: ZFA:0009234 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002494 ! cardiocyte is_a: CL:0010021 ! cardiac myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of UBERON:0001133 ! cardiac muscle tissue [Term] id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 xref: ZFA:0009235 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000192 ! smooth muscle cell relationship: develops_into CL:0000192 ! smooth muscle cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000514" xsd:string {name="smooth muscle myoblast on CELLxGENE CellGuide"} [Term] id: CL:0000515 name: skeletal muscle myoblast def: "A myoblast that differentiates into skeletal muscle fibers." [SANBI:mhl] subset: cellxgene_subset synonym: "skeletal myoblast" EXACT [] xref: FMA:84799 xref: ZFA:0009236 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0008002 ! skeletal muscle fiber relationship: develops_from CL:0000355 ! multi-potent skeletal muscle stem cell relationship: develops_into CL:0008002 ! skeletal muscle fiber [Term] id: CL:0000518 name: phagocyte (sensu Vertebrata) def: "A phagocyte in vertebrates that is able to phagocytosis." [GOC:tfm] is_a: CL:0000234 ! phagocyte is_a: CL:0000255 ! eukaryotic cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: CL:0000521 name: fungal cell def: "Any cell that in taxon some Fungi." [FBC:Autogenerated] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: in_taxon NCBITaxon:4751 ! Fungi relationship: in_taxon NCBITaxon:4751 ! Fungi [Term] id: CL:0000525 name: syncytiotrophoblast cell def: "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." [GOC:tfm, ISBN:0323052908] subset: cellxgene_subset subset: human_reference_atlas synonym: "plasmidotrophoblast cell" RELATED [] synonym: "syncytial trophoblast cell" EXACT [PMID:11787150] synonym: "syncytiotrophoblastic cell" EXACT [PMID:21733368] synonym: "syntrophoblast cell" RELATED [] xref: FMA:83043 is_a: CL:0000351 ! trophoblast cell is_a: CL:4052002 ! syncytial cell intersection_of: CL:0000351 ! trophoblast cell intersection_of: RO:0000053 PATO:0001908 ! bearer of multinucleate relationship: part_of UBERON:0000371 ! syncytiotrophoblast property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/2100" xsd:string [Term] id: CL:0000526 name: afferent neuron def: "A neuron which conveys sensory information centrally from the periphery." [GOC:tfm, MESH:D009475] subset: human_reference_atlas synonym: "input neuron" EXACT [] xref: FMA:87653 xref: ZFA:0009238 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000540 ! neuron property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000527 name: efferent neuron def: "A neuron which sends impulses peripherally to activate muscles or secretory cells." [MESH:D009476] subset: cellxgene_subset synonym: "output neuron" EXACT [] xref: ZFA:0009239 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000540 ! neuron [Term] id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. subset: cellxgene_subset subset: human_reference_atlas synonym: "nerve cell" EXACT [] xref: BTO:0000938 xref: CALOHA:TS-0683 xref: FBbt:00005106 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:54527 xref: VHOG:0001483 xref: WBbt:0003679 xref: ZFA:0009248 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000393 ! electrically responsive cell is_a: CL:0000404 ! electrically signaling cell is_a: CL:0002319 ! neural cell relationship: capable_of GO:0019226 ! transmission of nerve impulse relationship: develops_from CL:0000031 {gci_relation="in_taxon", gci_filler="NCBITaxon:7742", xref="https://github.com/obophenotype/cell-ontology/issues/757"} ! neuroblast (sensu Vertebrata) property_value: foaf:depiction "https://www.swissbiopics.org/api/image/Neuron_cells.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 xref: FMA:62863 xref: MESH:D008214 xref: VHOG:0001535 xref: ZFA:0009250 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000842 ! mononuclear leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin intersection_of: RO:0000053 PATO:0001407 ! bearer of mononucleate intersection_of: RO:0000053 PATO:0040072 ! bearer of high nuclear/cytoplasmic ratio disjoint_from: CL:0000766 ! myeloid leukocyte relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_part CL:0017500 ! neutrophillic cytoplasm relationship: has_part GO:0000792 ! heterochromatin relationship: RO:0000053 PATO:0040072 ! bearer of high nuclear/cytoplasmic ratio property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0000053 PATO:0002505 ! bearer of nucleated intersection_of: RO:0000053 PATO:0040072 ! bearer of high nuclear/cytoplasmic ratio intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part GO:0005730 ! nucleolus relationship: RO:0000053 PATO:0040072 ! bearer of high nuclear/cytoplasmic ratio relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] id: CL:0000549 name: basophilic erythroblast def: "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers." [GOC:tfm, ISBN:0721601464] subset: cellxgene_subset synonym: "basophilic normoblast" EXACT [ISBN:0721601464] synonym: "early erythroblast" EXACT [ISBN:0721601464] synonym: "early normoblast" EXACT [ISBN:0721601464] synonym: "prorubricyte" EXACT [ISBN:0721601464] xref: FMA:83505 xref: ZFA:0005236 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000765 {is_inferred="true"} ! erythroblast intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part GO:0000792 ! heterochromatin relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] id: CL:0000550 name: polychromatophilic erythroblast def: "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers." [ISBN:0721601464] subset: cellxgene_subset synonym: "intermediate erythroblast" EXACT [ISBN:0721601464] synonym: "intermediate normoblast" EXACT [ISBN:0721601464] synonym: "polychromatic erythroblast" EXACT [ISBN:0721601464] synonym: "polychromatic normoblast" EXACT [ISBN:0721601464] synonym: "polychromatophilic normoblast" EXACT [ISBN:0721601464] synonym: "rubricyte" EXACT [ISBN:0721601464] xref: FMA:83506 xref: ZFA:0005241 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000765 {is_inferred="true"} ! erythroblast intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017504 ! polychromatophilic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: develops_from CL:0000549 ! basophilic erythroblast relationship: has_part CL:0017504 ! polychromatophilic cytoplasm relationship: has_part GO:0000792 ! heterochromatin relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] id: CL:0000552 name: orthochromatic erythroblast def: "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." [ISBN:0721601464] subset: cellxgene_subset synonym: "acidophilic erythroblast" EXACT [ISBN:0721601464] synonym: "eosinophilic erythroblast" EXACT [ISBN:0721601464] synonym: "late erythoblast" EXACT [] synonym: "orthochromatic normoblast" EXACT [ISBN:0721601464] synonym: "pyknotic eto enrythroblast" EXACT [ISBN:0721601464] xref: FMA:84646 is_a: CL:0000765 {is_inferred="true"} ! erythroblast intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017502 ! acidophilic cytoplasm intersection_of: participates_in GO:0030263 ! apoptotic chromosome condensation relationship: develops_from CL:0000550 ! polychromatophilic erythroblast relationship: has_part CL:0017502 ! acidophilic cytoplasm relationship: participates_in GO:0030263 ! apoptotic chromosome condensation [Term] id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] synonym: "Meg-CFC" EXACT [PMCID:PMC1794060] synonym: "megacaryoblast" EXACT [] synonym: "megacaryocyte progenitor cell" EXACT [] synonym: "megakaryoblast" EXACT [] synonym: "megakaryocytic progenitor cell" EXACT [PMID:12482498] synonym: "MkP" EXACT [PMID:21116988] synonym: "promegacaryocyte" RELATED [] synonym: "promegakaryocyte" RELATED [] xref: BTO:0001164 xref: CALOHA:TS-0610 xref: FMA:84235 xref: MESH:D055016 is_a: CL:0000763 ! myeloid cell is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: capable_of GO:0007113 ! endomitotic cell cycle intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0007113 ! endomitotic cell cycle relationship: capable_of GO:0030219 ! megakaryocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000556 name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] synonym: "megalokaryocyte" EXACT [] xref: BTO:0000843 xref: CALOHA:TS-0611 xref: FMA:83555 is_a: CL:0000763 {is_inferred="true"} ! myeloid cell disjoint_from: CL:0000764 ! erythroid lineage cell relationship: develops_from CL:0000553 ! megakaryocyte progenitor cell relationship: RO:0000053 PATO:0001393 ! bearer of euploid property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000556" xsd:string {name="megakaryocyte on CELLxGENE CellGuide"} [Term] id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 xref: ZFA:0009252 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0071971 ! extracellular exosome assembly intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: capable_of GO:0071971 ! extracellular exosome assembly relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000552 ! orthochromatic erythroblast relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 [Term] id: CL:0000562 name: nucleate erythrocyte def: "An erythrocyte having a nucleus." [GOC:add, GOc:tfm] synonym: "RBC" BROAD [] synonym: "red blood cell" BROAD [] xref: ZFA:0009256 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000232 {is_inferred="true"} ! erythrocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000232 ! erythrocyte intersection_of: RO:0000053 PATO:0002505 ! bearer of nucleated relationship: develops_from CL:0002421 ! nucleated reticulocyte [Term] id: CL:0000566 name: angioblastic mesenchymal cell def: "A mesenchymal stem cell capable of developing into blood vessel endothelium." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive. synonym: "angioblast" EXACT [] synonym: "chondroplast" EXACT [] xref: ZFA:0009258 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: RO:0002104 PR:000001444 ! has plasma membrane part cadherin-5 intersection_of: RO:0002104 PR:000002112 ! has plasma membrane part vascular endothelial growth factor receptor 2 intersection_of: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute lymphocytic leukemia protein 1 relationship: develops_from CL:0000134 ! mesenchymal stem cell relationship: RO:0002104 PR:000001444 ! has plasma membrane part cadherin-5 relationship: RO:0002104 PR:000002112 ! has plasma membrane part vascular endothelial growth factor receptor 2 relationship: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute lymphocytic leukemia protein 1 [Term] id: CL:0000569 name: cardiac mesenchymal cell def: "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." [PMID:18816864] subset: cellxgene_subset xref: ZFA:0009259 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0008019 ! mesenchymal cell is_a: CL:2000073 ! migratory cardiac neural crest cell intersection_of: CL:0008019 ! mesenchymal cell intersection_of: develops_into CL:0002494 ! cardiocyte relationship: develops_into CL:0002494 ! cardiocyte [Term] id: CL:0000573 name: retinal cone cell def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949] subset: cellxgene_subset subset: human_reference_atlas synonym: "cone" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001036 xref: CALOHA:TS-0866 xref: FMA:67748 xref: ZFA:0009262 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: develops_from CL:0002672 ! retinal progenitor cell property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000573" xsd:string {name="retinal cone cell on CELLxGENE CellGuide"} [Term] id: CL:0000575 name: corneal epithelial cell def: "An epithelial cell of the cornea." [GOC:tfm] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "epithelial cell of cornea" EXACT [FMA:70551] xref: BTO:0004298 xref: CALOHA:TS-0173 xref: FMA:70551 xref: ZFA:0009264 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0001772 ! corneal epithelium relationship: part_of UBERON:0001772 ! corneal epithelium property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000575" xsd:string {name="corneal epithelial cell on CELLxGENE CellGuide"} [Term] id: CL:0000586 name: germ cell def: "The reproductive cell in multicellular organisms." [MESH:D005854] subset: cellxgene_subset xref: BTO:0000535 xref: NCIT:C12597 xref: VHOG:0001534 xref: WBbt:0006796 is_a: CL:0000039 {is_inferred="true"} ! germ line cell relationship: capable_of_part_of GO:0009566 ! fertilization [Term] id: CL:0000593 name: androgen secreting cell def: "A steroid hormone secreting cell that secretes androgen." [GOC:tfm] xref: ZFA:0009271 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000174 ! steroid hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0035935 ! androgen secretion relationship: capable_of GO:0035935 ! androgen secretion [Term] id: CL:0000604 name: retinal rod cell def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948] subset: cellxgene_subset subset: human_reference_atlas synonym: "rod" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001024 xref: CALOHA:TS-0870 xref: FMA:67747 xref: ZFA:0009275 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: develops_from CL:0002672 ! retinal progenitor cell property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000604" xsd:string {name="retinal rod cell on CELLxGENE CellGuide"} [Term] id: CL:0000622 name: acinar cell def: "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." [GOC:tfm, http://www.copewithcytokines.de] subset: cellxgene_subset synonym: "acinic cell" EXACT [] synonym: "acinous cell" EXACT [] xref: FMA:83625 xref: MESH:D061354 xref: ZFA:0009277 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000150 ! glandular secretory epithelial cell is_a: CL:0000154 ! protein secreting cell intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: CL:0000154 ! protein secreting cell intersection_of: part_of UBERON:0009842 ! glandular acinus relationship: part_of UBERON:0009842 ! glandular acinus property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000622" xsd:string {name="acinar cell on CELLxGENE CellGuide"} [Term] id: CL:0000630 name: supporting cell def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm] subset: cellxgene_subset synonym: "supportive cell" EXACT [] xref: BTO:0002315 xref: ZFA:0009387 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000000 ! cell [Term] id: CL:0000656 name: primary spermatocyte def: "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes." [GOC:tfm, ISBN:0721662544] xref: BTO:0001115 xref: CALOHA:TS-2194 xref: FMA:72292 is_a: CL:0000017 ! spermatocyte is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000017 ! spermatocyte intersection_of: capable_of GO:0007140 ! male meiotic nuclear division intersection_of: RO:0000053 PATO:0001394 ! bearer of diploid relationship: capable_of GO:0007140 ! male meiotic nuclear division relationship: RO:0000053 PATO:0001394 ! bearer of diploid [Term] id: CL:0000657 name: secondary spermatocyte def: "One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids." [GOC:tfm, ISBN:0721662544] xref: BTO:0000709 xref: CALOHA:TS-2195 xref: FBbt:00004941 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:72293 is_a: CL:0000017 ! spermatocyte is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000413 ! haploid cell intersection_of: CL:0000017 ! spermatocyte intersection_of: capable_of GO:0007142 ! male meiosis II intersection_of: RO:0000053 PATO:0001375 ! bearer of haploid relationship: capable_of GO:0007142 ! male meiosis II relationship: develops_from CL:0000656 ! primary spermatocyte [Term] id: CL:0000666 name: fenestrated endothelial cell def: "An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues." [DOI:10.1007/978-3-211-99390-3_133] subset: cellxgene_subset synonym: "window cell" EXACT [] xref: ZFA:0009286 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: RO:0000053 PATO:0002064 ! bearer of fenestrated relationship: RO:0000053 PATO:0002064 ! bearer of fenestrated property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000666" xsd:string {name="fenestrated endothelial cell on CELLxGENE CellGuide"} [Term] id: CL:0000667 name: collagen secreting cell def: "An extracellular matrix secreting cell that secretes collagen." [GOC:tfm] subset: cellxgene_subset xref: ZFA:0009287 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000327 ! extracellular matrix secreting cell [Term] id: CL:0000670 name: primordial germ cell def: "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." [GOC:tfm, PMID:1381289] subset: cellxgene_subset synonym: "gonocyte" EXACT [] synonym: "primitive germ cell" EXACT [] xref: FMA:70567 xref: ZFA:0009288 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000039 {is_inferred="true"} ! germ line cell is_a: CL:0000219 {is_inferred="true"} ! motile cell intersection_of: CL:0000039 ! germ line cell intersection_of: capable_of GO:0048870 ! cell motility intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo [Term] id: CL:0000675 name: female gamete def: "A mature sexual reproductive cell of the female germline." [GOC:tfm] is_a: CL:0000021 {is_inferred="true"} ! female germ cell is_a: CL:0000300 ! gamete [Term] id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] subset: cellxgene_subset xref: ZFA:0009291 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0011026 ! progenitor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell relationship: develops_into CL:0000187 ! muscle cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000680" xsd:string {name="muscle precursor cell on CELLxGENE CellGuide"} [Term] id: CL:0000696 name: PP cell def: "A cell that stores and secretes pancreatic polypeptide hormone." [GOC:tfm, JB:jb, PMID:15153415] subset: cellxgene_subset synonym: "type F enteroendocrine cell" EXACT [] xref: FMA:62938 xref: FMA:83409 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000167 ! peptide hormone secreting cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000696" xsd:string {name="PP cell on CELLxGENE CellGuide"} [Term] id: CL:0000710 name: neurecto-epithelial cell def: "Epithelial cells derived from neural plate and neural crest." [GOC:tfm] comment: The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098). synonym: "neuroepithelial cell" BROAD [] xref: BTO:0004301 xref: FMA:70557 is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002077 ! ecto-epithelial cell intersection_of: CL:0002077 ! ecto-epithelial cell intersection_of: develops_from CL:0000133 ! neurectodermal cell relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000723 name: somatic stem cell def: "A stem cell that can give rise to cell types of the body other than those of the germ-line." [GO:0048103] xref: CALOHA:TS-2086 xref: MESH:D053687 xref: ZFA:0009307 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000034 ! stem cell intersection_of: CL:0000034 ! stem cell intersection_of: capable_of GO:0048103 ! somatic stem cell division relationship: capable_of GO:0048103 ! somatic stem cell division property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000723" xsd:string {name="somatic stem cell on CELLxGENE CellGuide"} [Term] id: CL:0000737 name: striated muscle cell def: "Muscle cell which has as its direct parts myofilaments organized into sarcomeres." [GOC:tfm, ISBN:0721662544] xref: BTO:0002916 xref: CALOHA:TS-2157 xref: FMA:86936 xref: ZFA:0005784 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: has_part GO:0030017 ! sarcomere intersection_of: RO:0000053 PATO:0001410 ! bearer of striated disjoint_from: CL:0008000 ! non-striated muscle cell relationship: has_part GO:0030017 ! sarcomere relationship: RO:0000053 PATO:0001410 ! bearer of striated [Term] id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] subset: cellxgene_subset subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] synonym: "white blood cell" EXACT [] xref: BTO:0000751 xref: CALOHA:TS-0549 xref: FMA:62852 xref: MESH:D007962 xref: NCIT:C12529 xref: ZFA:0009309 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000219 ! motile cell is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0001667 ! ameboidal-type cell migration intersection_of: RO:0000053 PATO:0002505 ! bearer of nucleated relationship: capable_of GO:0001667 ! ameboidal-type cell migration relationship: develops_from CL:0000037 ! hematopoietic stem cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002405 ! immune system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000740 name: retinal ganglion cell def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "gangliocyte" EXACT [] synonym: "ganglion cell of retina" EXACT [] synonym: "RGC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] synonym: "RGCs" RELATED OMO:0003004 [doi:10.1038/s41598-020-66092-9] xref: BTO:0001800 xref: FMA:67765 xref: MESH:D012165 xref: ZFA:0009310 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000540 ! neuron relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: RO:0002100 UBERON:0000966 ! has soma location retina property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000740" xsd:string {name="retinal ganglion cell on CELLxGENE CellGuide"} [Term] id: CL:0000746 name: cardiac muscle cell def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263] comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. subset: cellxgene_subset subset: human_reference_atlas synonym: "cardiac muscle fiber" EXACT [GO:0048739] synonym: "cardiac myocyte" EXACT [] synonym: "cardiocyte" BROAD [] synonym: "cardiomyocyte" EXACT [] synonym: "heart muscle cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:14067 xref: MESH:D032383 xref: ZFA:0009316 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000737 ! striated muscle cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000187 ! muscle cell intersection_of: has_part GO:0030017 ! sarcomere intersection_of: part_of UBERON:0007100 ! primary circulatory organ intersection_of: participates_in GO:0060047 ! heart contraction intersection_of: RO:0000053 PATO:0002478 ! bearer of transversely striated relationship: develops_from CL:0000513 ! cardiac muscle myoblast relationship: participates_in GO:0060047 ! heart contraction relationship: RO:0000053 PATO:0002478 ! bearer of transversely striated property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000746" xsd:string {name="cardiac muscle cell on CELLxGENE CellGuide"} [Term] id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 xref: ZFA:0009324 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: develops_from CL:0000049 ! common myeloid progenitor relationship: develops_from CL:0000049 ! common myeloid progenitor [Term] id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 xref: FMA:62845 xref: FMA:83516 xref: ZFA:0009325 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000763 ! myeloid cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 xref: FMA:83504 xref: MESH:D004900 xref: ZFA:0005237 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: CL:4030045 GO:0005730 ! lacks_part nucleolus intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part GO:0005634 ! nucleus relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: CL:4030045 GO:0005730 ! lacks_part nucleolus relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000547 ! proerythroblast relationship: has_part GO:0005634 ! nucleus [Term] id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] subset: cellxgene_subset xref: ZFA:0009326 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte intersection_of: develops_from CL:0000049 ! common myeloid progenitor property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0000766" xsd:string {name="myeloid leukocyte on CELLxGENE CellGuide"} [Term] id: CL:0000783 name: multinucleated phagocyte def: "A phagocyte formed by the fusion of mononuclear phagocytes." [GOC:add, GOC:tfm] is_a: CL:0000228 ! multinucleate cell is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata) intersection_of: RO:0000053 PATO:0001908 ! bearer of multinucleate [Term] id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] subset: cellxgene_subset synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] synonym: "progenitor T cell" EXACT [] synonym: "TN1 cell" NARROW [] xref: ZFA:0009350 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000838 {is_inferred="true"} ! lymphoid lineage restricted progenitor cell intersection_of: CL:0000838 ! lymphoid lineage restricted progenitor cell intersection_of: capable_of GO:0030217 ! T cell differentiation relationship: capable_of GO:0030217 ! T cell differentiation relationship: develops_from CL:0000051 ! common lymphoid progenitor [Term] id: CL:0000837 name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] xref: BTO:0000725 xref: CALOHA:TS-0448 xref: ZFA:0009354 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0000053 PATO:0001402 ! bearer of multipotent intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000037 ! hematopoietic stem cell relationship: RO:0000053 PATO:0001402 ! bearer of multipotent relationship: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. subset: cellxgene_subset synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 xref: FMA:70338 xref: ZFA:0009355 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: capable_of GO:0030098 ! lymphocyte differentiation disjoint_from: CL:0000839 ! myeloid lineage restricted progenitor cell relationship: capable_of GO:0030098 ! lymphocyte differentiation [Term] id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 xref: CALOHA:TS-2099 xref: FMA:70339 xref: ZFA:0009356 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: capable_of GO:0030099 ! myeloid cell differentiation relationship: capable_of GO:0030099 ! myeloid cell differentiation property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000842 name: mononuclear leukocyte def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim subset: cellxgene_subset synonym: "mononuclear cell" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 xref: CALOHA:TS-0768 xref: FMA:86713 xref: ZFA:0009357 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000226 ! single nucleate cell is_a: CL:0000738 {is_inferred="true"} ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: RO:0000053 PATO:0001407 ! bearer of mononucleate [Term] id: CL:0000847 name: ciliated olfactory receptor neuron def: "An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob." [PMID:16841163] synonym: "ciliated olfactory sensory neuron" EXACT [] synonym: "ciliated sensory neuron" EXACT [] xref: ZFA:0009358 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000064 ! ciliated cell is_a: CL:0000207 ! olfactory receptor cell intersection_of: CL:0000207 ! olfactory receptor cell intersection_of: has_part GO:0005929 ! cilium [Term] id: CL:0000850 name: serotonergic neuron def: "A neuron that releases serotonin as a neurotransmitter." [SANBI:mhl] synonym: "5-HT neuron" EXACT [] synonym: "5-hydroxytryptamine neuron" EXACT [] synonym: "serotinergic neuron" RELATED [] xref: FBbt:00005133 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: MESH:D059326 xref: WBbt:0006837 xref: ZFA:0009361 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000458 ! serotonin secreting cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0060096 ! serotonin secretion, neurotransmission relationship: capable_of GO:0060096 ! serotonin secretion, neurotransmission [Term] id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] xref: BTO:0000574 xref: CALOHA:TS-2017 xref: FMA:70366 xref: FMA:83598 xref: ZFA:0005830 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000000 ! cell [Term] id: CL:0001035 name: bone cell def: "A connective tissue cell found in bone." [GO_REF:0000034, GOC:add] subset: general_cell_types_upper_slim subset: human_reference_atlas is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001474 ! bone element relationship: dc-contributor https://orcid.org/0000-0001-9990-8331 relationship: part_of UBERON:0001474 ! bone element property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0001035" xsd:string {name="bone cell on CELLxGENE CellGuide"} creation_date: 2011-11-16T04:28:16Z [Term] id: CL:0001060 name: hematopoietic oligopotent progenitor cell, lineage-negative def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." [GOC:tfm, PMID:19022770] is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: RO:0000053 PATO:0001401 ! bearer of oligopotent relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0001066 name: erythroid progenitor cell, mammalian def: "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." [GOC:add, ISBN:0721601464] subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] synonym: "CFU-E" RELATED OMO:0003000 [] synonym: "colony forming unit erythroid" RELATED [] synonym: "erythroid stem cell" RELATED [] xref: BTO:0004911 is_a: CL:0000038 ! erythroid progenitor cell intersection_of: CL:0000038 ! erythroid progenitor cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0001066" xsd:string {name="erythroid progenitor cell, mammalian on CELLxGENE CellGuide"} [Term] id: CL:0002031 name: hematopoietic lineage restricted progenitor cell def: "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." [GOC:tfm, PMID:19022770] subset: blood_and_immune_upper_slim is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: RO:0000053 PATO:0001400 ! bearer of unipotent disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: RO:0000053 PATO:0001400 ! bearer of unipotent creation_date: 2010-01-06T03:43:20Z [Term] id: CL:0002032 name: hematopoietic oligopotent progenitor cell def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities." [GOC:tfm, https://orcid.org/0000-0001-5208-3432, PMID:19022770] comment: This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060). subset: blood_and_immune_upper_slim subset: cellxgene_subset is_a: CL:0000255 ! eukaryotic cell is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: RO:0000053 PATO:0001401 ! bearer of oligopotent relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000837 ! hematopoietic multipotent progenitor cell relationship: RO:0000053 PATO:0001401 ! bearer of oligopotent creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0002064 name: pancreatic acinar cell def: "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells, ISBN:0517223651, PMID:20395539] subset: cellxgene_subset subset: human_reference_atlas synonym: "acinar cell of pancreas" EXACT [] xref: BTO:0000028 xref: CALOHA:TS-0737 xref: FMA:63032 xref: ZFA:0005739 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000622 {is_inferred="true"} ! acinar cell is_a: CL:1001599 ! pancreas exocrine glandular cell intersection_of: CL:0000622 ! acinar cell intersection_of: part_of UBERON:0001263 ! pancreatic acinus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_part GO:0042589 ! zymogen granule membrane relationship: part_of UBERON:0001263 ! pancreatic acinus property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002064" xsd:string {name="pancreatic acinar cell on CELLxGENE CellGuide"} creation_date: 2010-06-24T03:16:29Z [Term] id: CL:0002067 name: type A enteroendocrine cell def: "An enteroendocrine cell that produces glucagon." [GOC:tfm, ISBN:0412046911] subset: cellxgene_subset xref: FMA:62939 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000170 ! glucagon secreting cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: capable_of GO:0070091 ! glucagon secretion relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002067" xsd:string {name="type A enteroendocrine cell on CELLxGENE CellGuide"} creation_date: 2010-09-10T10:48:54Z [Term] id: CL:0002068 name: Purkinje myocyte def: "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter." [FMA:0412046911, GOC:tfm, PMID:19939742] subset: human_reference_atlas synonym: "myocytus conducens cardiacus" EXACT [] synonym: "Purkinje cell fiber" EXACT [] synonym: "Purkinje muscle cell" EXACT [] xref: BTO:0001032 xref: FMA:14146 is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-06-28T08:36:15Z [Term] id: CL:0002072 name: nodal myocyte def: "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." [FMA:67101, GOC:tfm] subset: human_reference_atlas synonym: "cardiac pacemaker cell" EXACT [GOC:pr] synonym: "myocytus nodalis" EXACT [] synonym: "P cell" EXACT [] synonym: "pacemaker cell" BROAD [] xref: BTO:0004190 xref: FMA:67101 is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-06-29T11:41:37Z [Term] id: CL:0002073 name: transitional myocyte def: "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." [FMA:67142, GOC:tfm] xref: FMA:67142 is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T02:39:32Z [Term] id: CL:0002074 name: myocardial endocrine cell def: "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides)." [FMA:67111, GOC:tfm] xref: FMA:67111 is_a: CL:0000163 ! endocrine cell is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T11:50:47Z [Term] id: CL:0002076 name: endo-epithelial cell def: "An epithelial cell derived from endoderm." [FMA:69075, GOC:tfm] subset: cellxgene_subset xref: FMA:69075 xref: ZFA:0009383 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: develops_from CL:0000223 ! endodermal cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000223 ! endodermal cell creation_date: 2010-06-29T03:38:14Z [Term] id: CL:0002077 name: ecto-epithelial cell def: "An epithelial cell derived from ectoderm." [FMA:69074, GOC:tfm] xref: FMA:69074 xref: ZFA:0009385 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: develops_from CL:0000221 ! ectodermal cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000221 ! ectodermal cell creation_date: 2010-06-29T03:38:22Z [Term] id: CL:0002078 name: meso-epithelial cell def: "Epithelial cell derived from mesoderm or mesenchyme." [FMA:69076, GOC:tfm] synonym: "epithelial mesenchymal cell" EXACT [] xref: FMA:69076 xref: ZFA:0009388 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: develops_from CL:0000222 ! mesodermal cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000222 ! mesodermal cell creation_date: 2010-06-29T03:49:14Z [Term] id: CL:0002079 name: pancreatic ductal cell def: "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." [FMA:63099, GOC:tfm, PMID:14740223] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:63099 xref: ZFA:0009380 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000069 ! branched duct epithelial cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0001064 ! ventral pancreatic duct relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001064 ! ventral pancreatic duct property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002079" xsd:string {name="pancreatic ductal cell on CELLxGENE CellGuide"} creation_date: 2010-06-30T08:49:43Z [Term] id: CL:0002080 name: pancreatic centro-acinar cell def: "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types." [GOC:tfm, PMID:12142741, PMID:20018761, PMID:8185160] subset: human_reference_atlas synonym: "centroacinar cell of Langerhans" EXACT [] synonym: "pancreatic centroacinar cell" EXACT [] xref: FMA:62455 xref: ZFA:0005740 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0001263 ! pancreatic acinus relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001263 ! pancreatic acinus property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-06-30T08:49:52Z [Term] id: CL:0002086 name: specialized cardiac myocyte def: "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." [FMA:67968, GOC:tfm] xref: FMA:67968 is_a: CL:0000746 ! cardiac muscle cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-21T01:33:38Z [Term] id: CL:0002087 name: nongranular leukocyte def: "A leukocyte that lacks granules." [GOC:tfm] subset: blood_and_immune_upper_slim synonym: "agranular leukocyte" EXACT [] xref: FMA:62855 is_a: CL:0000738 {is_inferred="true"} ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: CL:4030045 GO:0030141 ! lacks_part secretory granule relationship: CL:4030045 GO:0030141 ! lacks_part secretory granule relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-22T11:30:33Z [Term] id: CL:0002088 name: interstitial cell of Cajal def: "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise." [GOC:tfm, PMID:16460275, PMID:19520112] comment: Some argue this cell type is of mesenchymal origin. subset: cellxgene_subset subset: human_reference_atlas synonym: "ICC" EXACT [] synonym: "intestinal pacemaker cell" EXACT [GOC:pr] xref: BTO:0003914 xref: FMA:86573 is_a: CL:0000710 {is_inferred="true"} ! neurecto-epithelial cell intersection_of: CL:0000710 ! neurecto-epithelial cell intersection_of: capable_of GO:0043134 ! regulation of hindgut contraction relationship: capable_of GO:0043134 ! regulation of hindgut contraction relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002088" xsd:string {name="interstitial cell of Cajal on CELLxGENE CellGuide"} creation_date: 2010-07-22T03:26:00Z [Term] id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. subset: cellxgene_subset xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 is_a: CL:0001035 {is_inferred="true"} ! bone cell intersection_of: CL:0001035 ! bone cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002371 ! bone marrow creation_date: 2010-07-22T04:48:15Z [Term] id: CL:0002095 name: hilus cell of ovary def: "A cell in the hilum of the ovary that produces androgens." [GOC:tfm, ISBN:068340007X] subset: human_reference_atlas synonym: "hilar cell of ovary" EXACT [] xref: FMA:18710 is_a: CL:0000593 ! androgen secreting cell is_a: CL:0002132 ! stromal cell of ovary relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-08-23T11:18:18Z [Term] id: CL:0002132 name: stromal cell of ovary def: "A stomal cell of the ovary" [GOC:tfm] subset: cellxgene_subset synonym: "ovarian stromal cell" EXACT [GOC:cjm] xref: FMA:72299 is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0000992 ! ovary relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000992 ! ovary property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002132" xsd:string {name="stromal cell of ovary on CELLxGENE CellGuide"} creation_date: 2010-08-23T12:10:31Z [Term] id: CL:0002134 name: stromal cell of ovarian medulla def: "A stromal cell of the ovarian medulla." [GOC:tfm] xref: FMA:256171 is_a: CL:0002132 {is_inferred="true"} ! stromal cell of ovary intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0013192 ! ovarian medulla relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0013192 ! ovarian medulla creation_date: 2010-08-23T12:12:17Z [Term] id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 xref: CALOHA:TS-1106 xref: FMA:67755 is_a: CL:0000115 ! endothelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002139" xsd:string {name="endothelial cell of vascular tree on CELLxGENE CellGuide"} creation_date: 2010-08-24T02:06:40Z [Term] id: CL:0002144 name: capillary endothelial cell def: "An endothelial cell found in capillaries." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004956 xref: CALOHA:TS-0112 xref: FMA:67756 is_a: CL:0002653 ! squamous endothelial cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0001915 ! endothelium of capillary relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001915 ! endothelium of capillary property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002144" xsd:string {name="capillary endothelial cell on CELLxGENE CellGuide"} creation_date: 2010-08-24T10:15:00Z [Term] id: CL:0002148 name: dental pulp cell def: "A cell found within the dental pulp." [GOC:tfm, PMID:36267574] xref: CALOHA:TS-0195 xref: FMA:87170 is_a: CL:0002159 ! general ecto-epithelial cell is_a: CL:0002320 ! connective tissue cell intersection_of: CL:0002159 ! general ecto-epithelial cell intersection_of: part_of UBERON:0001754 ! dental pulp relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001754 ! dental pulp creation_date: 2010-08-24T02:52:09Z [Term] id: CL:0002149 name: epithelial cell of uterus def: "An epithelial cell of the uterus. This cell has a mesodermal origin." [GOC:tfm, PMID:11331626, PMID:16960017, PMID:21698266] subset: cellxgene_subset xref: FMA:256161 is_a: CL:0002078 ! meso-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0006955 ! uterine epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0006955 ! uterine epithelium creation_date: 2010-08-24T10:45:54Z [Term] id: CL:0002152 name: columnar cell of endocervix def: "A simple columnar epithelial cell located in the endocervix." [doi:/10.1016/j.autneu.2015.04.008, GOC:tfm, ISBN:0721662544] xref: FMA:86486 is_a: CL:0000146 ! simple columnar epithelial cell is_a: CL:0002535 ! epithelial cell of cervix intersection_of: CL:0000146 ! simple columnar epithelial cell intersection_of: part_of UBERON:0012252 ! endocervical epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0012252 ! endocervical epithelium creation_date: 2010-08-24T10:47:47Z [Term] id: CL:0002159 name: general ecto-epithelial cell def: "Epithelial cells derived from general body ectoderm and ectoderm placodes." [GOC:tfm] xref: FMA:70556 is_a: CL:0002077 ! ecto-epithelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-26T08:31:08Z [Term] id: CL:0002166 name: epithelial cell of Malassez def: "An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth." [GOC:tfm, ISBN:0517223651, ISBN:0815129521] synonym: "epithelial cell rests of Malassez" EXACT [] synonym: "epithelial debris of Malassez" EXACT [] xref: FMA:62987 is_a: CL:0002159 {is_inferred="true"} ! general ecto-epithelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0011595 ! jaw region creation_date: 2010-08-26T08:51:27Z [Term] id: CL:0002178 name: epithelial cell of stomach def: "An epithelial cell found in the lining of the stomach." [GOC:tfm] subset: cellxgene_subset xref: FMA:62948 is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001276 ! epithelium of stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001276 ! epithelium of stomach creation_date: 2010-08-25T03:22:08Z [Term] id: CL:0002180 name: mucous cell of stomach def: "An epithelial cell of the stomach. This cell produces mucous." [GOC:tfm] subset: cellxgene_subset xref: FMA:63464 is_a: CL:0000319 ! mucus secreting cell is_a: CL:0002178 ! epithelial cell of stomach is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0070254 ! mucus secretion intersection_of: part_of UBERON:0001276 ! epithelium of stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-25T03:38:51Z [Term] id: CL:0002183 name: stem cell of gastric gland def: "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit." [GOC:tfm, ISBN:0517223651] xref: FMA:62953 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: CL:0002178 ! epithelial cell of stomach intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0000325 ! gastric gland relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000325 ! gastric gland creation_date: 2010-08-25T03:57:08Z [Term] id: CL:0002195 name: hepatic stem cell def: "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes)." [GOC:tfm, PMID:26798363] synonym: "HpSC" RELATED OMO:0003000 [PMID:18442648] xref: FMA:86577 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002107 ! liver property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string creation_date: 2010-08-30T02:00:42Z [Term] id: CL:0002202 name: epithelial cell of tracheobronchial tree def: "An epithelial cell of the tracheobronchial tree." [GOC:tfm] xref: FMA:66816 is_a: CL:0002632 ! epithelial cell of lower respiratory tract intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0008397 ! tracheobronchial epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0008397 ! tracheobronchial epithelium creation_date: 2010-09-02T02:09:14Z [Term] id: CL:0002209 name: intermediate epitheliocyte def: "An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells." [GOC:tfm, ISBN:0517223651] synonym: "undifferentiated columnar cell of tracheobronchial tree" EXACT [] xref: FMA:69060 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-02T02:53:59Z [Term] id: CL:0002222 name: vertebrate lens cell def: "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye." [GOC:tfm, ISBN:0721662544] subset: eye_upper_slim xref: FMA:70950 is_a: CL:0000066 ! epithelial cell is_a: CL:0000306 ! crystallin accumulating cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000965 ! lens of camera-type eye creation_date: 2010-09-07T10:38:03Z [Term] id: CL:0002224 name: lens epithelial cell def: "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [GOC:tfm, http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium, ISBN:0721662544] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67559 is_a: CL:0000075 {is_inferred="true"} ! columnar/cuboidal epithelial cell is_a: CL:0002222 ! vertebrate lens cell intersection_of: CL:0000075 ! columnar/cuboidal epithelial cell intersection_of: part_of UBERON:0001803 ! epithelium of lens relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001803 ! epithelium of lens property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002224" xsd:string {name="lens epithelial cell on CELLxGENE CellGuide"} creation_date: 2010-09-07T10:45:47Z [Term] id: CL:0002240 name: marrow fibroblast def: "A fibroblast in the bone marrow." [GOC:tfm] xref: FMA:84377 is_a: CL:0000057 ! fibroblast is_a: CL:0010001 ! stromal cell of bone marrow intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T02:25:18Z [Term] id: CL:0002241 name: pulmonary interstitial fibroblast def: "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis." [GOC:tfm] comment: The marker set DPT, APOD can identify the Human cell type pulmonary interstitial fibroblast in the lung with a confidence of 0.58 (NS-Forest FBeta value). {xref="https://doi.org/10.5281/zenodo.11165918"} subset: cellxgene_subset synonym: "pulmonary myofibroblast" EXACT [] synonym: "pulmonary septal cell" EXACT [] xref: FMA:84467 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:4030031 ! interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001004 ! respiratory system intersection_of: part_of UBERON:0005169 ! interstitial tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001004 ! respiratory system relationship: RO:0015004 CLM:1000046 ! has characterizing marker set property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002241" xsd:string {name="pulmonary interstitial fibroblast on CELLxGENE CellGuide"} creation_date: 2010-09-07T02:29:38Z [Term] id: CL:0002242 name: nucleate cell def: "A cell containing at least one nucleus." [GOC:tfm] xref: FMA:67513 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: RO:0000053 PATO:0002505 ! bearer of nucleated relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: RO:0000053 PATO:0002505 ! bearer of nucleated creation_date: 2010-09-07T03:32:33Z [Term] id: CL:0002243 name: smooth muscle cell of sphincter of pupil def: "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells." [GOC:tfm, ISBN:0721662544, ISBN:0721694128] subset: cellxgene_subset synonym: "smooth muscle fiber of sphincter of pupil" EXACT [] synonym: "smooth muscle fibre of sphincter of pupil" RELATED [] xref: FMA:70611 is_a: CL:0000358 {is_inferred="true"} ! sphincter associated smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001607 ! sphincter pupillae relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000133 ! neurectodermal cell relationship: part_of UBERON:0001607 ! sphincter pupillae property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002243" xsd:string {name="smooth muscle cell of sphincter of pupil on CELLxGENE CellGuide"} creation_date: 2010-09-08T08:53:42Z [Term] id: CL:0002244 name: squamous cell of ectocervix def: "A stratified squamous epithelial cell located in the ectocervix." [doi:/10.1016/j.autneu.2015.04.008, GOC:tfm, http://www.bu.edu/histology/p/19404loa.htm, PMID:32644501] synonym: "ectocervical squamous cell" EXACT [] xref: FMA:86483 is_a: CL:1001575 ! uterine cervix squamous cell intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0012251 ! ectocervical epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0012251 ! ectocervical epithelium creation_date: 2010-09-08T09:12:23Z [Term] id: CL:0002246 name: peripheral blood stem cell def: "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells)." [GOC:tfm] synonym: "PBSC" EXACT [] xref: BTO:0002669 xref: FMA:86711 xref: MESH:D000072916 is_a: CL:0000037 {is_inferred="true"} ! hematopoietic stem cell is_a: CL:0000080 ! circulating cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0000178 ! blood relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000178 ! blood creation_date: 2010-09-07T03:57:09Z [Term] id: CL:0002250 name: intestinal crypt stem cell def: "A stem cell located in epithelium the based of the crypt of Lieberkuhn. Division of these cells serve both to maintain the stem cell population and produce the transit amplifying cells that are all precursors of all cell types that populate the intestinal epithelium." [GOC:tfm, ISBN:0517223651] subset: cellxgene_subset synonym: "stem cell of intestinal crypt of Lieberkuhn" EXACT [] xref: FMA:63379 is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0000034 ! stem cell intersection_of: part_of UBERON:0001983 ! crypt of Lieberkuhn relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001983 ! crypt of Lieberkuhn property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002250" xsd:string {name="intestinal crypt stem cell on CELLxGENE CellGuide"} creation_date: 2010-09-08T09:21:22Z [Term] id: CL:0002251 name: epithelial cell of alimentary canal def: "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus." [GOC:tfm, ISBN:0721662544] is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0003929 ! digestive tract epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003929 ! digestive tract epithelium creation_date: 2010-09-08T09:26:53Z [Term] id: CL:0002252 name: epithelial cell of esophagus def: "An epithelial cell of the lining of the esophagus." [GOC:tfm] subset: cellxgene_subset xref: FMA:63071 xref: ZFA:0009400 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001976 ! epithelium of esophagus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001976 ! epithelium of esophagus creation_date: 2010-09-08T09:28:20Z [Term] id: CL:0002253 name: epithelial cell of large intestine def: "An epithelial cell of the lining of the large intestine." [GOC:tfm] subset: cellxgene_subset synonym: "epithelial cell of colon" RELATED [] xref: BTO:0004297 xref: FMA:256157 is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001278 ! epithelium of large intestine creation_date: 2010-09-08T09:28:22Z [Term] id: CL:0002254 name: epithelial cell of small intestine def: "An epithelial cell of the lining of the small intestine." [GOC:tfm] subset: cellxgene_subset xref: FMA:256159 is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002108 ! small intestine creation_date: 2010-09-08T09:41:46Z [Term] id: CL:0002255 name: stromal cell of endometrium def: "A stromal cell of the endometrium, characterized by its fibroblast-like morphology, regenerative capacity, and ability to undergo decidualization. It differentiates into a decidual stromal cell during pregnancy, essential for embryo implantation and maintenance. This cell is involved in tissue proliferation, remodeling, and breakdown, responding to hormonal changes, particularly estrogen and progesterone." [https://doi.org/10.1038/s41591-020-1040-z, PMID:11331626, PMID:30013421, PMID:30309298, PMID:31907034, Wikipedia:Decidualization] subset: cellxgene_subset subset: human_reference_atlas synonym: "endometrial stromal cell" EXACT [] synonym: "endometrial stromal fibroblast" EXACT [PMID:30309298] synonym: "stromal cell of uterus" BROAD [] xref: CALOHA:TS-1266 xref: FMA:86490 is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0002337 ! endometrial stroma relationship: capable_of GO:0046697 ! decidualization relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002337 ! endometrial stroma relationship: RO:0002388 CL:2000002 ! has potential to directly develop into decidual cell property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-08T09:50:04Z [Term] id: CL:0002262 name: endothelial cell of sinusoid def: "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." [GOC:tfm, ISBN:0618947256] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:63134 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0003909 ! sinusoid relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003909 ! sinusoid property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002262" xsd:string {name="endothelial cell of sinusoid on CELLxGENE CellGuide"} creation_date: 2010-09-14T10:57:26Z [Term] id: CL:0002264 name: type A cell of stomach def: "A type of enteroendocrine cell found in the stomach that secretes glucagon." [GOC:tfm] xref: FMA:83411 is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:1001517 ! stomach enteroendocrine cell intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: part_of UBERON:0001276 ! epithelium of stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T10:54:42Z [Term] id: CL:0002265 name: type D cell of colon def: "A D cell located in the colon." [GOC:tfm] synonym: "colon D-cell" EXACT [] synonym: "colonic delta cell" EXACT [] synonym: "delta cell of colon" EXACT [] xref: FMA:268744 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009042 ! enteroendocrine cell of colon is_a: CL:1001588 ! colon glandular cell intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) creation_date: 2010-09-10T11:37:35Z [Term] id: CL:0002266 name: type D cell of small intestine def: "A type D cell of the small intestine." [GOC:tfm] synonym: "delta cell of small intestine" EXACT [] synonym: "small intestine D-cell" EXACT [] synonym: "small intestine delta cell" EXACT [] xref: FMA:268736 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009006 ! enteroendocrine cell of small intestine intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) creation_date: 2010-09-10T01:34:22Z [Term] id: CL:0002267 name: type D cell of stomach def: "A type D cell found in the stomach." [GOC:tfm] synonym: "delta cell of stomach" EXACT [] synonym: "stomach D-cell" EXACT [] synonym: "stomach delta cell" EXACT [] xref: FMA:83410 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0002659 ! glandular epithelial cell of stomach is_a: CL:1000222 ! stomach neuroendocrine cell intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0001276 ! epithelium of stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T01:36:03Z [Term] id: CL:0002275 name: pancreatic PP cell def: "A PP cell located in the islets of the pancreas." [GOC:tfm] comment: The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell. subset: cellxgene_subset subset: human_reference_atlas synonym: "pancreatic polypeptide-secreting cell" EXACT [] synonym: "PP cell of pancreatic islet" EXACT [] synonym: "PP-cell of pancreatic islet" EXACT [] xref: BTO:0000805 xref: FMA:70588 xref: MESH:D050418 xref: ZFA:0005742 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000696 ! PP cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: part_of UBERON:0000006 ! islet of Langerhans intersection_of: part_of UBERON:0001264 ! pancreas relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002275" xsd:string {name="pancreatic PP cell on CELLxGENE CellGuide"} creation_date: 2010-09-10T03:30:31Z [Term] id: CL:0002308 name: epithelial cell of skin gland def: "An epithelial cell of a skin gland." [GOC:tfm] synonym: "epithelial cell of gland of skin" EXACT [] xref: FMA:70657 is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002419 ! skin gland relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002419 ! skin gland creation_date: 2010-09-14T12:00:07Z [Term] id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] subset: cellxgene_subset subset: general_cell_types_upper_slim xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001016 ! nervous system relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001016 ! nervous system creation_date: 2010-09-15T01:34:57Z [Term] id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, which includes adipose tissue, cartilage, and bone. In vertebrates, this cell arises chiefly from the embryonic mesoderm and, in cranial regions, from neural crest." [GOC:tfm, ISBN:0618947256, PMID:19198652, PMID:26043871, PMID:31194383] subset: cellxgene_subset subset: general_cell_types_upper_slim xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 xref: ZFA:0009392 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0002384 ! connective tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002384 ! connective tissue creation_date: 2010-09-15T03:01:54Z [Term] id: CL:0002321 name: embryonic cell (metazoa) def: "A cell of the embryo." [FMA:0618947256] xref: CALOHA:TS-0263 xref: FMA:82840 xref: WBbt:0007028 xref: ZFA:0007089 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000000 ! cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002321" xsd:string {name="embryonic cell (metazoa) on CELLxGENE CellGuide"} creation_date: 2010-09-15T03:39:21Z [Term] id: CL:0002328 name: bronchial epithelial cell def: "An epithelial cell of the bronchus." [GOC:tfm] subset: cellxgene_subset xref: BTO:0002922 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002031 ! epithelium of bronchus creation_date: 2010-09-20T02:00:00Z [Term] id: CL:0002333 name: neural crest derived adipocyte def: "An adipocyte derived from a neural crest cell." [GOC:tfm, PMID:17507398] is_a: CL:0000136 ! adipocyte intersection_of: CL:0000136 ! adipocyte intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000005 ! neural crest derived fibroblast creation_date: 2010-09-20T02:25:25Z [Term] id: CL:0002350 name: endocardial cell def: "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." [GOC:tfm, ISSN:0452-3458] subset: cellxgene_subset subset: human_reference_atlas synonym: "endocardial endothelial cell" EXACT [] synonym: "endothelial cell of endocardium" EXACT [FMA:75621] xref: FMA:75621 is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0002165 ! endocardium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002165 ! endocardium property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002350" xsd:string {name="endocardial cell on CELLxGENE CellGuide"} creation_date: 2010-09-21T04:33:05Z [Term] id: CL:0002351 name: progenitor cell of endocrine pancreas def: "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1." [GOC:tfm, PMID:20025937, PMID:20217494, PMID:22728667] subset: cellxgene_subset synonym: "pancreatic endocrine progenitor" EXACT [] synonym: "pancreatic islet progenitor cell" EXACT [] is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-21T04:41:06Z [Term] id: CL:0002352 name: gestational hematopoietic stem cell def: "A hematopoietic stem cell that exists during embryogenesis." [GOC:tfm, ISBN:978-60327-246-6] is_a: CL:0000037 ! hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0000922 ! embryo relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000922 ! embryo creation_date: 2010-09-22T09:05:13Z [Term] id: CL:0002359 name: placental hematopoietic stem cell def: "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells." [GOC:tfm, ISBN:978-1-60327-346-6] is_a: CL:0002352 ! gestational hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001987 ! placenta creation_date: 2010-09-22T10:30:02Z [Term] id: CL:0002363 name: keratocyte def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." [GOC:tfm, ISBN:9780702029585] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "corneal fibroblast" EXACT [] synonym: "corneal keratocyte" EXACT [] is_a: CL:0000005 ! neural crest derived fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001777 ! substantia propria of cornea relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001777 ! substantia propria of cornea property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002363" xsd:string {name="keratocyte on CELLxGENE CellGuide"} creation_date: 2010-09-22T01:57:40Z [Term] id: CL:0002368 name: respiratory tract epithelial cell def: "An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin." [GOC:tfm] subset: cellxgene_subset synonym: "airway epithelial cell" EXACT [] synonym: "respiratory epithelial cell" EXACT [] xref: BTO:0004533 is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004802 ! respiratory tract epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004802 ! respiratory tract epithelium creation_date: 2010-09-23T04:38:49Z [Term] id: CL:0002372 name: myotube def: "A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development." [GOC:dos, GOC:tfm, ISBN:0323052908, PMID:22274696] subset: cellxgene_subset synonym: "myofiber" EXACT [FBbt:00005812] synonym: "myofibril" EXACT [FBbt:00005812] xref: FBbt:00005812 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: CL:0000737 ! striated muscle cell is_a: CL:4052002 ! syncytial cell intersection_of: CL:0000187 ! muscle cell intersection_of: has_part GO:0030017 ! sarcomere intersection_of: RO:0000053 PATO:0001908 ! bearer of multinucleate intersection_of: RO:0000053 PATO:0002478 ! bearer of transversely striated relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: RO:0000053 PATO:0002478 ! bearer of transversely striated property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002372" xsd:string {name="myotube on CELLxGENE CellGuide"} creation_date: 2010-09-24T01:13:01Z [Term] id: CL:0002375 name: Schwann cell precursor def: "A multipotent progenitor cell that develops from a migratory neural crest cell. The schwann cell precursor is embedded among axons, with minimal extracellular space separating them from nerve cell membranes. This cell lacks a basal lamina, which distinguishes it from more mature Schwann cells. In rodents, cadherin-19 (Cdh19) serves as a specific marker for this developmental stage." [GOC:tfm, PMID:15580626, PMID:30971890, PMID:35815410] comment: Schwann cell precursor are capable of differentiating into Schwann cells and other cell types such as melanocytes, neurons, and mesenchymal cells. {xref="PMID:35815410"} subset: cellxgene_subset synonym: "Schwann cell precursor cell" EXACT [] synonym: "SCP" RELATED OMO:0003000 [PMID:35815410] is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000333 ! migratory neural crest cell relationship: has_potential_to_develop_into CL:0002573 ! Schwann cell relationship: RO:0000053 PATO:0001402 ! bearer of multipotent property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002375" xsd:string {name="Schwann cell precursor on CELLxGENE CellGuide"} creation_date: 2010-09-24T02:06:10Z [Term] id: CL:0002377 name: immature Schwann cell def: "A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons." [GOC:cvs, GOC:tfm, ISBN:0721662544] subset: cellxgene_subset synonym: "Schwann cell" BROAD [] xref: ZFA:0001725 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002573 ! Schwann cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002375 ! Schwann cell precursor property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002377" xsd:string {name="immature Schwann cell on CELLxGENE CellGuide"} creation_date: 2010-09-24T02:10:31Z [Term] id: CL:0002421 name: nucleated reticulocyte def: "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles." [GOC:tfm, PMID:18182572, PMID:9011180, PMID:9046052] is_a: CL:0000558 {is_inferred="true"} ! reticulocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000558 ! reticulocyte intersection_of: RO:0000053 PATO:0002505 ! bearer of nucleated relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-10-15T09:24:05Z [Term] id: CL:0002453 name: oligodendrocyte precursor cell def: "A proliferative and migratory glial progenitor cell that derives from a neural stem cell and resides within the central nervous system. It possesses the capacity to differentiate into a committed oligodendrocyte progenitor (COP) through a well-defined series of maturation steps, ultimately giving rise to a myelinating oligodendrocyte (MOL). In mice and humans, it is characterized by the expression of specific molecular markers, including Pdgfra, Cspg4 (also known as NG2) and Olig2." [GOC:tfm, PMID:16367798, PMID:20142420, PMID:31583586, PMID:31726662, PMID:37653126] subset: cellxgene_subset subset: human_reference_atlas synonym: "NG2 cell" RELATED [PMID:14501223] synonym: "O2-A" RELATED OMO:0003000 [PMID:2182078] synonym: "OPC" RELATED OMO:0003000 [PMID:14501223] synonym: "Polydendrocyte" RELATED [PMID:23516142] xref: MESH:D000073637 is_a: CL:0000123 ! neuron associated cell (sensu Vertebrata) is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000047 ! neural stem cell relationship: develops_from CL:0000339 ! glioblast (sensu Vertebrata) relationship: develops_into CL:4023059 ! committed oligodendrocyte precursor relationship: part_of CL:0000125 ! glial cell relationship: part_of UBERON:0001017 ! central nervous system property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002453" xsd:string {name="oligodendrocyte precursor cell on CELLxGENE CellGuide"} creation_date: 2010-11-10T02:51:34Z [Term] id: CL:0002491 name: auditory epithelial cell def: "A specialized cell involved in auditory sensory perception." [GOC:tfm] subset: cellxgene_subset is_a: CL:0000098 ! sensory epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-12-06T03:18:43Z [Term] id: CL:0002494 name: cardiocyte def: "A cell located in the heart, including both muscle and non muscle cells." [GOC:tfm] comment: From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart. synonym: "heart cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:83808 xref: FMA:84791 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0007100 ! primary circulatory organ relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0007100 ! primary circulatory organ creation_date: 2010-12-07T09:37:22Z [Term] id: CL:0002503 name: adventitial cell def: "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" [GOC:tfm] subset: cellxgene_subset xref: BTO:0002441 xref: FMA:84639 is_a: CL:0000630 ! supporting cell is_a: CL:0002320 ! connective tissue cell intersection_of: CL:0002320 ! connective tissue cell intersection_of: part_of UBERON:0005742 ! adventitia relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0005742 ! adventitia creation_date: 2010-12-07T04:03:56Z [Term] id: CL:0002504 name: enteric smooth muscle cell def: "A smooth muscle cell of the intestine." [GOC:tfm] subset: cellxgene_subset synonym: "intestinal smooth muscle cell" EXACT [] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0000160 ! intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000160 ! intestine property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002504" xsd:string {name="enteric smooth muscle cell on CELLxGENE CellGuide"} creation_date: 2011-01-17T03:39:38Z [Term] id: CL:0002518 name: kidney epithelial cell def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ] subset: cellxgene_subset xref: KUPO:0001019 xref: ZFA:0009374 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000066 ! epithelial cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002113 ! kidney relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-08T10:46:34Z [Term] id: CL:0002521 name: subcutaneous adipocyte def: "An adipocyte that is part of subcutaneous adipose tissue." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "subcutaneous fat cell" EXACT [] is_a: CL:0000136 {is_inferred="true"} ! adipocyte intersection_of: CL:0000136 ! adipocyte intersection_of: part_of UBERON:0002190 ! subcutaneous adipose tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002190 ! subcutaneous adipose tissue property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002521" xsd:string {name="subcutaneous adipocyte on CELLxGENE CellGuide"} creation_date: 2011-02-21T02:51:22Z [Term] id: CL:0002535 name: epithelial cell of cervix def: "An epithelial cell of the cervix." [GOC:tfm] synonym: "cervical canal epithelial cell" EXACT [GOC:tfm] synonym: "cervical canal of uterus epithelial cell" EXACT [GOC:tfm] synonym: "cervix epithelial cell" EXACT [GOC:tfm] synonym: "cervix of uterus epithelial cell" EXACT [GOC:tfm] synonym: "epithelial cell of cervical canal" EXACT [GOC:tfm] synonym: "epithelial cell of cervical canal of uterus" EXACT [GOC:tfm] synonym: "epithelial cell of cervix of uterus" EXACT [GOC:tfm] synonym: "epithelial cell of neck of uterus" EXACT [GOC:tfm] synonym: "epithelial cell of uterine cervix" EXACT [GOC:tfm] synonym: "neck of uterus epithelial cell" EXACT [GOC:tfm] synonym: "uterine cervix epithelial cell" EXACT [GOC:tfm] is_a: CL:0002149 ! epithelial cell of uterus intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000002 ! uterine cervix relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004801 ! cervix epithelium creation_date: 2011-02-24T08:20:08Z [Term] id: CL:0002538 name: intrahepatic cholangiocyte def: "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes." [GOC:tfm, PMID:23720296] subset: cellxgene_subset synonym: "small bile duct cholangiocyte" EXACT [PMID:23720296] xref: ZFA:0009379 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:1000488 {is_inferred="true"} ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: part_of UBERON:0004823 ! intrahepatic bile duct epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004823 ! intrahepatic bile duct epithelium property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002538" xsd:string {name="intrahepatic cholangiocyte on CELLxGENE CellGuide"} creation_date: 2011-02-28T01:20:20Z [Term] id: CL:0002539 name: aortic smooth muscle cell def: "A smooth muscle cell of the aorta." [GOC:tfm] subset: cellxgene_subset xref: BTO:0004577 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0004178 ! aorta smooth muscle tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004178 ! aorta smooth muscle tissue property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002539" xsd:string {name="aortic smooth muscle cell on CELLxGENE CellGuide"} creation_date: 2011-02-28T01:42:12Z [Term] id: CL:0002540 name: mesenchymal stem cell of the bone marrow def: "A mesenchymal stem cell that is part of the bone marrow." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T01:47:47Z [Term] id: CL:0002541 name: chorionic membrane mesenchymal stem cell def: "A mesenchymal stem cell of the chorionic membrane." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003124 ! chorion membrane creation_date: 2011-02-28T03:04:35Z [Term] id: CL:0002543 name: vein endothelial cell def: "An endothelial cell that is part of the vein." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "endothelial cell of vein" EXACT [] synonym: "venous endothelial cell" EXACT [] xref: FMA:62104 xref: KUPO:0001099 is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0001638 ! vein relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001638 ! vein property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002543" xsd:string {name="vein endothelial cell on CELLxGENE CellGuide"} creation_date: 2011-02-28T03:48:11Z [Term] id: CL:0002547 name: fibroblast of the aortic adventitia def: "A fibroblast of the aortic adventitia." [GOC:tfm] subset: cellxgene_subset is_a: CL:1000306 {is_inferred="true"} ! fibroblast of tunica adventitia of artery intersection_of: CL:1000306 ! fibroblast of tunica adventitia of artery intersection_of: part_of UBERON:0004664 ! aorta tunica adventitia relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004664 ! aorta tunica adventitia creation_date: 2011-02-28T04:43:41Z [Term] id: CL:0002548 name: fibroblast of cardiac tissue def: "A fibroblast that is part of the heart." [GOC:tfm] subset: cellxgene_subset synonym: "cardiac fibroblast" EXACT [] is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:0002494 {is_inferred="true"} ! cardiocyte intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000948 ! heart relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000948 ! heart property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002548" xsd:string {name="fibroblast of cardiac tissue on CELLxGENE CellGuide"} creation_date: 2011-02-28T04:57:44Z [Term] id: CL:0002551 name: fibroblast of dermis def: "Any skin fibroblast that is part of some dermis." [FBC:Autogenerated] subset: cellxgene_subset is_a: CL:0002620 {is_inferred="true"} ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0002067 ! dermis relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002067 ! dermis creation_date: 2011-02-28T05:05:33Z [Term] id: CL:0002552 name: fibroblast of gingiva def: "Any fibroblast that is part of some gingiva." [FBC:Autogenerated] is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001828 ! gingiva relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001828 ! gingiva creation_date: 2011-02-28T05:09:12Z [Term] id: CL:0002553 name: fibroblast of lung def: "A fibroblast that is part of lung." [GOC:tfm] subset: cellxgene_subset xref: BTO:0000764 xref: CALOHA:TS-0575 is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002048 ! lung relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002048 ! lung creation_date: 2011-02-28T05:11:03Z [Term] id: CL:0002556 name: fibroblast of periodontium def: "A fibroblast of the periodontium." [GOC:tfm] is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001758 ! periodontium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001758 ! periodontium creation_date: 2011-02-28T05:19:48Z [Term] id: CL:0002557 name: fibroblast of pulmonary artery def: "A fibroblast of pulmonary artery." [GOC:tfm] subset: human_reference_atlas is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002012 ! pulmonary artery property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-02-28T05:22:27Z [Term] id: CL:0002563 name: intestinal epithelial cell def: "An epithelial cell of the lining of the intestine." [GOC:tfm] subset: cellxgene_subset xref: ZFA:0009399 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001277 ! intestinal epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001277 ! intestinal epithelium creation_date: 2011-03-01T05:18:31Z [Term] id: CL:0002569 name: mesenchymal stem cell of umbilical cord def: "A mesenchymal stem cell of the umbilical cord." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0000349 ! extraembryonic cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0003422 ! mesenchyme of umbilical cord relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003422 ! mesenchyme of umbilical cord creation_date: 2011-03-01T09:55:12Z [Term] id: CL:0002570 name: mesenchymal stem cell of adipose tissue def: "A mesenchymal stem cell of adipose tissue." [GOC:tfm] subset: cellxgene_subset synonym: "mesenchymal stem cell of adipose" EXACT [] is_a: CL:0000134 ! mesenchymal stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0001013 ! adipose tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001013 ! adipose tissue property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002570" xsd:string {name="mesenchymal stem cell of adipose tissue on CELLxGENE CellGuide"} creation_date: 2011-03-01T09:57:17Z [Term] id: CL:0002571 name: hepatic mesenchymal stem cell def: "A mesenchymal stem cell of liver." [GOC:tfm] is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0002195 ! hepatic stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-01T09:58:51Z [Term] id: CL:0002572 name: vertebral mesenchymal stem cell def: "A mesenchymal stem cell of the vertebrae." [GOC:tfm] is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0001035 ! bone cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002412 ! vertebra relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002412 ! vertebra creation_date: 2011-03-01T10:40:27Z [Term] id: CL:0002573 name: Schwann cell def: "A glial cell that myelinates or ensheathes axons in the peripheral nervous system." [GOC:tfm, PMID:16807057] comment: A myelinating Schwann cell wraps around a single axon. Myelination occurs in larger diameter axons, while a process called ensheathment occurs on smaller diameter axons in which a single cell wraps around multiple small, unmyelinated axons separating them with a thin layer of cytoplasm. The structure formed is called a Remak bundle. {xref="PMID:16807057"} subset: cellxgene_subset subset: human_reference_atlas synonym: "neurolemmocyte" EXACT [PMID:32119275, PMID:38638689] xref: BTO:0001220 xref: CALOHA:TS-0898 xref: MESH:D012583 is_a: CL:0000125 ! glial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000010 ! peripheral nervous system property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002573" xsd:string {name="Schwann cell on CELLxGENE CellGuide"} creation_date: 2011-03-02T01:19:27Z [Term] id: CL:0002574 name: stromal cell of pancreas def: "A stromal cell of the pancreas." [GOC:tfm] subset: human_reference_atlas is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-02T02:40:41Z [Term] id: CL:0002577 name: placental epithelial cell def: "An epithelial cell of the placenta." [GOC:tfm] is_a: CL:0000066 ! epithelial cell is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001987 ! placenta creation_date: 2011-03-02T03:21:30Z [Term] id: CL:0002584 name: renal cortical epithelial cell def: "An epithelial cell of the kidney cortex." [GOC:tfm] xref: KUPO:0001016 is_a: CL:0002518 {is_inferred="true"} ! kidney epithelial cell is_a: CL:0002681 {is_inferred="true"} ! kidney cortical cell intersection_of: CL:0002518 ! kidney epithelial cell intersection_of: part_of UBERON:0001225 ! cortex of kidney [Term] id: CL:0002585 name: retinal blood vessel endothelial cell def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm] subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell is_a: CL:0009004 ! retinal cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0000966 ! retina relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000966 ! retina property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002585" xsd:string {name="retinal blood vessel endothelial cell on CELLxGENE CellGuide"} creation_date: 2011-03-06T03:28:27Z [Term] id: CL:0002589 name: smooth muscle cell of the brachiocephalic vasculature def: "A smooth muscle cell of the bachiocephalic vasculature." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001529 ! brachiocephalic artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001529 ! brachiocephalic artery creation_date: 2011-03-06T05:00:58Z [Term] id: CL:0002590 name: smooth muscle cell of the brain vasculature def: "A vascular associated smooth muscle cell of the brain vasculature." [GOC:tfm] subset: cellxgene_subset is_a: CL:0000359 {is_inferred="true"} ! vascular associated smooth muscle cell is_a: CL:0002319 ! neural cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0000955 ! brain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000955 ! brain creation_date: 2011-03-06T05:01:20Z [Term] id: CL:0002591 name: smooth muscle cell of the pulmonary artery def: "A smooth muscle of the pulmonary artery." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0003336 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002012 ! pulmonary artery property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002591" xsd:string {name="smooth muscle cell of the pulmonary artery on CELLxGENE CellGuide"} creation_date: 2011-03-06T05:01:28Z [Term] id: CL:0002594 name: smooth muscle cell of the umbilical artery def: "A smooth muscle cell of the umbilical artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001310 ! umbilical artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001310 ! umbilical artery creation_date: 2011-03-06T05:01:48Z [Term] id: CL:0002595 name: smooth muscle cell of the subclavian artery def: "A smooth muscle cell of the subclavian artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001533 ! subclavian artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001533 ! subclavian artery creation_date: 2011-03-06T05:01:52Z [Term] id: CL:0002596 name: smooth muscle cell of the carotid artery def: "Smooth muscle cell of the carotid artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0005396 ! carotid artery segment relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0005396 ! carotid artery segment creation_date: 2011-03-06T05:01:56Z [Term] id: CL:0002597 name: smooth muscle cell of bladder def: "A smooth muscle cell of the bladder." [GC:tfm] subset: human_reference_atlas xref: KUPO:0001122 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1001319 ! bladder cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-06T05:43:24Z [Term] id: CL:0002598 name: bronchial smooth muscle cell def: "Any smooth muscle cell that is part of some bronchus." [FBC:Autogenerated] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004402 is_a: CL:0019019 ! tracheobronchial smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002185 ! bronchus property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002598" xsd:string {name="bronchial smooth muscle cell on CELLxGENE CellGuide"} creation_date: 2011-03-06T05:46:39Z [Term] id: CL:0002599 name: smooth muscle cell of the esophagus def: "A smooth muscle cell of the esophagus." [GOC:tfm] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001043 ! esophagus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001043 ! esophagus creation_date: 2011-03-06T05:48:17Z [Term] id: CL:0002600 name: smooth muscle cell of trachea def: "A smooth muscle cell of the trachea." [GOC:tfm] subset: cellxgene_subset is_a: CL:0019019 ! tracheobronchial smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0003126 ! trachea relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003126 ! trachea property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002600" xsd:string {name="smooth muscle cell of trachea on CELLxGENE CellGuide"} creation_date: 2011-03-06T05:50:28Z [Term] id: CL:0002601 name: uterine smooth muscle cell def: "A smooth muscle cell of the uterus." [GOC:tfm] subset: cellxgene_subset is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0000995 ! uterus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000995 ! uterus property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002601" xsd:string {name="uterine smooth muscle cell on CELLxGENE CellGuide"} creation_date: 2011-03-06T05:53:28Z [Term] id: CL:0002610 name: raphe nuclei neuron def: "A neuron of the raphe nuclei." [GOC:tfm] is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0004684 ! has soma location raphe nuclei relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: RO:0002100 UBERON:0004684 ! has soma location raphe nuclei creation_date: 2011-03-06T07:42:06Z [Term] id: CL:0002612 name: neuron of the ventral spinal cord def: "A neuron of the ventral spinal cord." [GOC:tfm] is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0002257 ! has soma location ventral horn of spinal cord relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: RO:0002100 UBERON:0002257 ! has soma location ventral horn of spinal cord creation_date: 2011-03-06T07:46:03Z [Term] id: CL:0002620 name: skin fibroblast def: "A fibroblast of skin." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001255 xref: CALOHA:TS-0935 is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002097 ! skin of body relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002097 ! skin of body property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002620" xsd:string {name="skin fibroblast on CELLxGENE CellGuide"} creation_date: 2011-03-14T12:31:49Z [Term] id: CL:0002625 name: seminiferous tubule epithelial cell def: "A cell of the seminiferous tubule epithelium." [GOC:tfm] is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004813 ! seminiferous tubule epithelium creation_date: 2011-03-15T11:59:23Z [Term] id: CL:0002631 name: epithelial cell of upper respiratory tract def: "Any epithelial cell that is part of some upper respiratory tract epithelium." [FBC:Autogenerated] is_a: CL:0002368 ! respiratory tract epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004814 ! upper respiratory tract epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004814 ! upper respiratory tract epithelium creation_date: 2011-06-21T12:28:55Z [Term] id: CL:0002632 name: epithelial cell of lower respiratory tract def: "Any epithelial cell that is part of some lower respiratory tract epithelium." [FBC:Autogenerated] subset: cellxgene_subset is_a: CL:0002368 ! respiratory tract epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004815 ! lower respiratory tract epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004815 ! lower respiratory tract epithelium creation_date: 2011-06-21T12:29:31Z [Term] id: CL:0002653 name: squamous endothelial cell def: "A squamous shaped endothelial cell." [GOC:dos] is_a: CL:0000115 ! endothelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T03:31:25Z [Term] id: CL:0002656 name: glandular endometrial unciliated epithelial cell def: "A glandular epithelial cell of the endometrium. Following ovulation, these cells secrete a glycogen-rich substance known as histotroph or uterine milk, which nourishes the embryo if implantation occurs." [GOC:tfm, PMID:25023676] synonym: "glandular cell of endometrium" BROAD [] xref: FMA:86489 is_a: CL:0000150 ! glandular secretory epithelial cell is_a: CL:0000152 ! exocrine cell is_a: CL:0009084 ! glandular epithelial cell of endometrium is_a: CL:1001591 ! oviduct secretory cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0032940 ! secretion by cell intersection_of: part_of UBERON:0002451 ! endometrial gland relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002451 ! endometrial gland creation_date: 2011-07-08T03:54:08Z [Term] id: CL:0002657 name: glandular cell of esophagus def: "A glandular epithelial cell of the esophagus." [GOC:tfm] subset: cellxgene_subset xref: FMA:86548 is_a: CL:0000150 {is_inferred="true"} ! glandular secretory epithelial cell is_a: CL:0002252 {is_inferred="true"} ! epithelial cell of esophagus intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0001976 ! epithelium of esophagus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T03:55:57Z [Term] id: CL:0002658 name: glandular cell of the large intestine def: "A glandular epithelial cell of the large intestine." [GOC:tfm] xref: FMA:87194 is_a: CL:0000150 {is_inferred="true"} ! glandular secretory epithelial cell is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T04:03:01Z [Term] id: CL:0002659 name: glandular epithelial cell of stomach def: "A glandular epithelial cell that is part of the stomach." [GOC:tfm] synonym: "glandular cell of stomach" EXACT [] xref: CALOHA:TS-1284 xref: FMA:86554 is_a: CL:0000150 ! glandular secretory epithelial cell is_a: CL:0002178 ! epithelial cell of stomach intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0001276 ! epithelium of stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-11T01:20:35Z [Term] id: CL:0002663 name: myocardial endocrine cell of atrium def: "A myocardial endocrine cell that is part of the atrium." [GOC:tfm] xref: FMA:83389 is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002081 ! cardiac atrium creation_date: 2011-07-11T02:45:39Z [Term] id: CL:0002664 name: cardioblast def: "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart." [GOC:tfm, PMID:19745164] comment: Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell. synonym: "cardiovascular progenitor cell" EXACT [PMID:17519333, PMID:19745164] synonym: "CPC" RELATED OMO:0003000 [PMID:19745164] is_a: CL:0000048 ! multi fate stem cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-11T03:15:38Z [Term] id: CL:0002672 name: retinal progenitor cell def: "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." [GOC:tfm, PMID:20959166, PMID:21148186] subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000133 ! neurectodermal cell creation_date: 2011-08-16T02:38:01Z [Term] id: CL:0002673 name: tongue muscle cell def: "A skeletal muscle cell that is part of the tongue." [GOC:tfm, PMID:18816858] subset: cellxgene_subset is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: part_of UBERON:0000378 ! tongue muscle relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000378 ! tongue muscle property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0002673" xsd:string {name="tongue muscle cell on CELLxGENE CellGuide"} creation_date: 2011-08-16T03:10:02Z [Term] id: CL:0002676 name: neural crest derived neuroblast def: "A neuroblast derived from a neural crest cell." [GOC:tfm, PMID:17407019] is_a: CL:0000031 ! neuroblast (sensu Vertebrata) relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000333 ! migratory neural crest cell creation_date: 2011-08-22T09:24:15Z [Term] id: CL:0002680 name: PP cell of intestine def: "A PP cell found in intestine." [GOC:tfm, PMID:2420136, PMID:728970] is_a: CL:0000696 {is_inferred="true"} ! PP cell is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: part_of UBERON:0001277 ! intestinal epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-09-27T11:59:01Z [Term] id: CL:0002681 name: kidney cortical cell def: "A cell that is part of a cortex of kidney." [] is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001225 ! cortex of kidney relationship: dc-contributor https://orcid.org/0000-0002-0956-8634 relationship: part_of UBERON:0001225 ! cortex of kidney creation_date: 2011-10-25T03:49:41Z [Term] id: CL:0005000 name: spinal cord interneuron def: "A CNS interneuron located in the spinal cord." [CL:CVS] comment: Is_a interneuron, part_of UBERON:0002240. xref: ZFA:0000778 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000099 {is_inferred="true"} ! interneuron intersection_of: CL:0000099 ! interneuron intersection_of: RO:0002100 UBERON:0002240 ! has soma location spinal cord relationship: RO:0002100 UBERON:0002240 ! has soma location spinal cord [Term] id: CL:0005009 name: renal principal cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS] subset: cellxgene_subset xref: ZFA:0005322 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002518 ! kidney epithelial cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0005009" xsd:string {name="renal principal cell on CELLxGENE CellGuide"} [Term] id: CL:0005024 name: somatomotor neuron def: "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic." [ZFIN:CVS] synonym: "somatic motor neuron" EXACT [] xref: ZFA:0005733 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000100 ! motor neuron is_a: CL:0000108 ! cholinergic neuron intersection_of: CL:0000100 ! motor neuron intersection_of: RO:0002120 CL:0008002 ! synapsed to skeletal muscle fiber relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of RO:0002577 ! system relationship: RO:0002120 CL:0008002 ! synapsed to skeletal muscle fiber [Term] id: CL:0005026 name: hepatoblast def: "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation." [GOC:CVS, https://orcid.org/0000-0003-1940-6740, PMID:18356246, PMID:20483998, PMID:26798363] subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0005026" xsd:string {name="hepatoblast on CELLxGENE CellGuide"} property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string [Term] id: CL:0007000 name: preameloblast def: "Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins." [GO_REF:0000034, PMCID:PMC2737325] comment: unsure of neural crest contribution. In VSAO we have develops_from CL:0000008 is_a: CL:0011026 ! progenitor cell relationship: adjacent_to UBERON:0001763 ! odontogenic papilla relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: develops_from CL:0002077 ! ecto-epithelial cell relationship: part_of UBERON:0005176 ! tooth enamel organ creation_date: 2012-06-15T01:27:01Z [Term] id: CL:0007001 name: skeletogenic cell def: "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized)." [GO_REF:0000034] comment: Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts) synonym: "scleroblast" EXACT [GO_REF:0000034] is_a: CL:0000000 ! cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2012-06-15T02:51:27Z [Term] id: CL:0007002 name: precementoblast def: "Skeletogenic cell that has the potential to develop into a cementoblast." [GO_REF:0000034] is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: part_of UBERON:0005176 ! tooth enamel organ creation_date: 2012-06-15T04:37:13Z [Term] id: CL:0007003 name: preodontoblast def: "Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell." [GO_REF:0000034] is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0005176 ! tooth enamel organ creation_date: 2012-06-15T05:15:11Z [Term] id: CL:0007004 name: premigratory neural crest cell def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." [UBERONREF:0000002] subset: cellxgene_subset xref: ZFA:0007084 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0011012 ! neural crest cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: develops_from CL:0000133 ! neurectodermal cell relationship: part_of UBERON:0002342 ! neural crest creation_date: 2012-06-27T08:27:35Z [Term] id: CL:0007009 name: prechondroblast def: "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells." [GO_REF:0000034] is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2012-06-27T10:44:01Z [Term] id: CL:0008000 name: non-striated muscle cell def: "Any muscle cell in which the fibers are not organised into sarcomeres." [GOC:DOS] is_a: CL:0000187 ! muscle cell [Term] id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008002 name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] subset: cellxgene_subset xref: MESH:D018485 is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube intersection_of: CL:0000187 ! muscle cell intersection_of: has_part GO:0030017 ! sarcomere intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue intersection_of: RO:0000053 PATO:0001908 ! bearer of multinucleate intersection_of: RO:0000053 PATO:0002478 ! bearer of transversely striated relationship: develops_from CL:0000515 ! skeletal muscle myoblast [Term] id: CL:0008007 name: visceral muscle cell def: "A muscle cell that is part of some visceral muscle." [GOC:dos] xref: FBbt:00005070 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:8600004 ! visceral muscle tissue relationship: part_of UBERON:8600004 ! visceral muscle tissue [Term] id: CL:0008008 name: striated visceral muscle cell def: "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods." [GOC:dos] is_a: CL:0000737 ! striated muscle cell is_a: CL:0008007 ! visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: RO:0000053 PATO:0001410 {all_some="true"} ! bearer of striated [Term] id: CL:0008009 name: transversely striated visceral muscle cell def: "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods." [GOC:dos] is_a: CL:0008008 ! striated visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: RO:0000053 PATO:0002478 {all_some="true"} ! bearer of transversely striated relationship: RO:0000053 PATO:0002478 ! bearer of transversely striated [Term] id: CL:0008017 name: adult skeletal muscle myoblast def: "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers." [PMID:23303905] comment: The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins. subset: cellxgene_subset synonym: "myogenic precursor cell" BROAD [PMID:23303905] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0000515 ! skeletal muscle myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0008002 ! skeletal muscle fiber intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue [Term] id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell is_a: CL:0000255 ! eukaryotic cell relationship: capable_of GO:0016477 ! cell migration relationship: part_of UBERON:0003104 ! mesenchyme property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0008019" xsd:string {name="mesenchymal cell on CELLxGENE CellGuide"} [Term] id: CL:0008022 name: endocardial cushion cell def: "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves." [PMID:18816864] is_a: CL:0000569 ! cardiac mesenchymal cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000569 ! cardiac mesenchymal cell intersection_of: part_of UBERON:0002062 ! endocardial cushion relationship: part_of UBERON:0002062 ! endocardial cushion [Term] id: CL:0008024 name: pancreatic endocrine cell def: "An endocrine cell that is part of the pancreas." [GOC:dos] subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000164 ! enteroendocrine cell intersection_of: CL:0000163 ! endocrine cell intersection_of: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0008025 name: noradrenergic neuron def: "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter." [GOC:dos] xref: ZFA:0005873 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000459 ! noradrenergic cell is_a: CL:4033050 ! catecholaminergic neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission relationship: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission [Term] id: CL:0008028 name: visual system neuron def: "Any neuron that is capable of part of some visual perception." [FBC:Autogenerated] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of_part_of GO:0007601 ! visual perception relationship: capable_of_part_of GO:0007601 ! visual perception relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2017-07-09T19:12:36Z [Term] id: CL:0008031 name: cortical interneuron def: "An interneuron that has its soma located in the cerebral cortex." [] subset: cellxgene_subset synonym: "cerebral cortex interneuron" EXACT [] is_a: CL:0000099 ! interneuron is_a: CL:0010012 ! cerebral cortex neuron intersection_of: CL:0000099 ! interneuron intersection_of: RO:0002100 UBERON:0000956 ! has soma location cerebral cortex property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0008031" xsd:string {name="cortical interneuron on CELLxGENE CellGuide"} [Term] id: CL:0008034 name: mural cell def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194] subset: added_for_HCA subset: cellxgene_subset subset: human_reference_atlas xref: ZFA:0005944 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:4033054 ! perivascular cell relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2020-02-29T17:33:55Z [Term] id: CL:0008035 name: microcirculation associated smooth muscle cell def: "Any vascular associated smooth muscle cell that is part of some microcirculatory vessel." [FBC:Autogenerated] subset: cellxgene_subset is_a: CL:0000359 ! vascular associated smooth muscle cell is_a: CL:0008034 ! mural cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0010523 ! microcirculatory vessel relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 relationship: part_of UBERON:0010523 ! microcirculatory vessel creation_date: 2020-02-29T17:37:00Z [Term] id: CL:0008041 name: mesothelial cell of intestine def: "A mesothelial cell that is part of the intestinal serosa." [https://orcid.org/0000-0002-7073-9172] is_a: CL:0000077 ! mesothelial cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001243 ! serosa of intestine relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 relationship: part_of UBERON:0001243 ! serosa of intestine property_value: dcterms-date "2025-02-04T18:42:26Z" xsd:dateTime [Term] id: CL:0008055 name: respiratory tract secretory epithelial cell def: "A secretory epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin." [DOI:10.1038/s41591-023-02327-2.] is_a: CL:0002368 ! respiratory tract epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: part_of UBERON:0004802 ! respiratory tract epithelium property_value: dc-contributor "https://orcid.org/0000-0002-7073-9172" xsd:string property_value: dcterms-date "2025-02-19T16:01:02Z" xsd:dateTime [Term] id: CL:0009000 name: sensory neuron of spinal nerve def: "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord." [GOC:nv, GOC:pr] synonym: "spinal sensory neuron" EXACT [] is_a: CL:3000004 ! peripheral sensory neuron intersection_of: CL:0000101 ! sensory neuron intersection_of: RO:0002100 UBERON:0001780 ! has soma location spinal nerve relationship: RO:0002100 UBERON:0001780 ! has soma location spinal nerve [Term] id: CL:0009001 name: compound eye retinal cell def: "Any cell in the compound eye, a light sensing organ composed of ommatidia." [] xref: GOC:pr xref: PMID:12021768 is_a: CL:0009004 ! retinal cell [Term] id: CL:0009004 name: retinal cell def: "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:pr] xref: PMID:10702418 is_a: CL:0002319 ! neural cell intersection_of: CL:0002319 ! neural cell intersection_of: part_of UBERON:0005388 ! photoreceptor array relationship: part_of UBERON:0005388 ! photoreceptor array [Term] id: CL:0009006 name: enteroendocrine cell of small intestine def: "An enteroendocrine cell that is located in the small intestine." [http://orcid.org/0000-0003-3440-1876] subset: cellxgene_subset subset: location_grouping synonym: "small intestine enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell is_a: CL:1001598 ! small intestine secretory cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0009006" xsd:string {name="enteroendocrine cell of small intestine on CELLxGENE CellGuide"} [Term] id: CL:0009016 name: intestinal crypt stem cell of large intestine def: "An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells." [https://orcid.org/0000-0003-4183-8865, PMID:20683682] subset: cellxgene_subset subset: human_reference_atlas subset: location_grouping synonym: "crypt stem cell of large intestine" BROAD [] synonym: "stem cell of large intestine crypt of Lieberkuhn" EXACT [] is_a: CL:0002250 ! intestinal crypt stem cell is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0002250 ! intestinal crypt stem cell intersection_of: part_of UBERON:0001984 ! crypt of Lieberkuhn of large intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001984 ! crypt of Lieberkuhn of large intestine property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0009017 name: intestinal crypt stem cell of small intestine def: "An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells." [https://orcid.org/0000-0003-4183-8865, PMID:20683682] subset: cellxgene_subset subset: location_grouping synonym: "crypt stem cell of small intestine" BROAD [] synonym: "stem cell of small intestine crypt of Lieberkuhn" EXACT [] is_a: CL:0002250 ! intestinal crypt stem cell is_a: CL:0002254 ! epithelial cell of small intestine intersection_of: CL:0002250 ! intestinal crypt stem cell intersection_of: part_of UBERON:0001241 ! crypt of Lieberkuhn of small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001241 ! crypt of Lieberkuhn of small intestine property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0009017" xsd:string {name="intestinal crypt stem cell of small intestine on CELLxGENE CellGuide"} [Term] id: CL:0009018 name: lymphocyte of large intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the large intestine." [https://orcid.org/0000-0003-4183-8865] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: human_reference_atlas subset: location_grouping synonym: "lamina propria lymphocyte of large intestine" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0011189 ! lamina propria of large intestine property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0009019 name: nephrogenic zone cell def: "A kidney cortical cell that is part of the nephrogenic zone." [https://orcid.org/0000-0002-3163-0115, PMID:29449449] subset: added_for_HCA synonym: "cortical nephrogenic niche cell" EXACT [] synonym: "cortical nephrogenic zone cell" EXACT [] is_a: CL:0002681 ! kidney cortical cell intersection_of: CL:0002681 ! kidney cortical cell intersection_of: part_of UBERON:0009871 ! nephrogenic zone relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0009871 ! nephrogenic zone [Term] id: CL:0009021 name: stromal cell of lamina propria of large intestine def: "A stromal cell found in the lamina propria of the large intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0011189 ! lamina propria of large intestine [Term] id: CL:0009022 name: stromal cell of lamina propria of small intestine def: "A stromal cell found in the lamina propria of the small intestine." [http://orcid.org/0000-0003-4183-8865] subset: cellxgene_subset subset: location_grouping is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001238 ! lamina propria of small intestine [Term] id: CL:0009024 name: mesothelial cell of small intestine def: "A mesothelial cell that is part of the small intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping is_a: CL:0008041 ! mesothelial cell of intestine intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001206 ! serosa of small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001206 ! serosa of small intestine [Term] id: CL:0009025 name: mesothelial cell of colon def: "A mesothelial cell that is part of the colon." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "mesothelial cell of large intestine" BROAD [] is_a: CL:0008041 ! mesothelial cell of intestine intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0003335 ! serosa of colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0003335 ! serosa of colon [Term] id: CL:0009040 name: stromal cell of lamina propria of colon def: "A stromal cell found in the lamina propria of the colon." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "stromal cell of colon lamina propria" EXACT [] is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0007177 ! lamina propria of mucosa of colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0007177 ! lamina propria of mucosa of colon [Term] id: CL:0009042 name: enteroendocrine cell of colon def: "An enteroendocrine cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876] subset: cellxgene_subset subset: location_grouping synonym: "colon enteroendocrine cell" EXACT [] is_a: CL:0011108 ! colon epithelial cell is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009043 name: intestinal crypt stem cell of colon def: "An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon." [http://orcid.org/0000-0003-3440-1876, PMID:10841502] subset: cellxgene_subset subset: location_grouping is_a: CL:0009016 ! intestinal crypt stem cell of large intestine intersection_of: CL:0002250 ! intestinal crypt stem cell intersection_of: part_of UBERON:0013485 ! crypt of Lieberkuhn of colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0013485 ! crypt of Lieberkuhn of colon property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0009043" xsd:string {name="intestinal crypt stem cell of colon on CELLxGENE CellGuide"} [Term] id: CL:0009044 name: lymphocyte of small intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response." [https://orcid.org/0000-0003-4183-8865, PMID:26551552] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: location_grouping synonym: "gastrointestinal tract (lamina propria) lymphocyte of small intestine" EXACT [] synonym: "gastrointestinal tract small intestine (lamina propria) leukocyte" BROAD [] synonym: "lamina propria lymphocyte of small intestine" EXACT [] synonym: "small intestine lamina propria leukocyte" BROAD [] synonym: "small intestine lamina propria leukocyte (LPL)" BROAD [] synonym: "small intestine lamina propria lymphocyte" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001238 ! lamina propria of small intestine [Term] id: CL:0009051 name: T cell of anorectum def: "A T cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: location_grouping is_a: CL:0000084 ! T cell intersection_of: CL:0000084 ! T cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009052 name: smooth muscle cell of anorectum def: "A smooth muscle cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "anorectum smooth muscle cell" EXACT [] is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009053 name: stromal cell of anorectum lamina propria def: "A stromal cell found in the lamina propria of the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009061 name: intestinal crypt stem cell of anorectum def: "An intestinal crypt stem cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "anorectum intestinal crypt stem cell" EXACT [] is_a: CL:0009016 ! intestinal crypt stem cell of large intestine intersection_of: CL:0009016 ! intestinal crypt stem cell of large intestine intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009063 name: enteroendocrine cell of anorectum def: "An enteroendocrine cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "anorectum enteroendocrine cell" EXACT [] is_a: CL:0002253 ! epithelial cell of large intestine is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009084 name: glandular epithelial cell of endometrium def: "An epithelial cell that is part of an endometrium glandular epithelium." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: human_reference_atlas subset: location_grouping synonym: "endometrial glandular epithelial cell" EXACT [] synonym: "epithelial cell of endometrial gland" EXACT [] xref: EFO:0010710 is_a: CL:0002149 ! epithelial cell of uterus intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0012276 ! endometrium glandular epithelium relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0012276 ! endometrium glandular epithelium property_value: dcterms-date "2021-11-30T16:13:30Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0009092 name: endothelial cell of placenta def: "An endothelial cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: cellxgene_subset subset: location_grouping synonym: "placental endothelial cell" EXACT [] xref: EFO:0010708 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001987 ! placenta property_value: dcterms-date "2021-12-13T13:53:01Z" xsd:dateTime [Term] id: CL:0009093 name: smooth muscle cell of placenta def: "A smooth muscle cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "placental smooth muscle cell" EXACT [] xref: EFO:0010709 is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001987 ! placenta property_value: dcterms-date "2021-12-13T13:56:42Z" xsd:dateTime [Term] id: CL:0009094 name: endothelial cell of hepatic portal vein def: "An endothelial cell that is part of a hepatic portal vein." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865, PMID:30348985] subset: location_grouping synonym: "portal endothelial cell" BROAD [] xref: EFO:0010704 is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001639 ! hepatic portal vein relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001639 ! hepatic portal vein property_value: dcterms-date "2021-12-13T14:01:05Z" xsd:dateTime [Term] id: CL:0009095 name: endothelial cell of uterus def: "An endothelial cell that is part of a uterus." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: cellxgene_subset subset: location_grouping synonym: "uterine endothelial cell" EXACT [] xref: EFO:0010711 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000995 ! uterus relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0000995 ! uterus property_value: dcterms-date "2021-12-13T14:39:25Z" xsd:dateTime property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0009095" xsd:string {name="endothelial cell of uterus on CELLxGENE CellGuide"} [Term] id: CL:0009097 name: embryonic skeletal muscle fiber def: "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development." [http://orcid.org/0000-0003-2034-601X, PMID:32094117, PMID:7196501] is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: existence_starts_and_ends_during UBERON:0000068 ! embryo stage relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: existence_starts_and_ends_during UBERON:0000068 ! embryo stage property_value: dcterms-date "2022-02-21T15:39:10Z" xsd:dateTime [Term] id: CL:0009098 name: fetal and neonatal skeletal muscle fiber def: "A skeletal muscle fiber found at the fetal and neonatal stages. In mammalian fetuses and neonates, skeletal muscle expresses myosin heavy chain-neonatal (MyHC-neo, encoded by the MYH8 gene). This expression disappears shortly after birth and is replaced by expression of adult heavy chain myosins." [http://orcid.org/0000-0003-2034-601X, PMID:26180627, PMID:7196501] is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: existence_ends_during UBERON:0007221 ! neonate stage intersection_of: existence_starts_during UBERON:0000092 ! post-embryonic stage relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: existence_ends_during UBERON:0007221 ! neonate stage relationship: existence_starts_during UBERON:0000092 ! post-embryonic stage property_value: dcterms-date "2022-02-21T15:43:16Z" xsd:dateTime [Term] id: CL:0009100 name: hepatic portal fibroblast def: "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen." [https://orcid.org/0000-0001-7655-4833, PMID:20209607, PMID:24814904] subset: human_reference_atlas synonym: "portal fibroblast" BROAD [] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001279 ! portal triad relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001279 ! portal triad property_value: dcterms-date "2022-03-17T12:00:44Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0010001 name: stromal cell of bone marrow def: "A stromal cell that is part_of a bone marrow." [] subset: cellxgene_subset synonym: "bone marrow stromal cell" EXACT [] is_a: CL:0000499 ! stromal cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 [Term] id: CL:0010002 name: epithelial cell of umbilical artery def: "An epithelial cell that is part_of a umbilical artery." [] synonym: "umbilical artery epithelial cell" EXACT [] is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001310 ! umbilical artery relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 relationship: part_of UBERON:0001310 ! umbilical artery [Term] id: CL:0010004 name: mononuclear cell of bone marrow def: "A mononuclear cell that is part_of a bone marrow." [] synonym: "bone marrow mononuclear cell" EXACT [] is_a: CL:0000842 ! mononuclear leukocyte is_a: CL:1001610 ! bone marrow hematopoietic cell intersection_of: CL:0000842 ! mononuclear leukocyte intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 [Term] id: CL:0010006 name: cardiac blood vessel endothelial cell def: "Any blood vessel endothelial cell that is part of some heart." [FBC:Autogenerated] subset: cellxgene_subset is_a: CL:0000071 ! blood vessel endothelial cell is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0000948 ! heart property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0010006" xsd:string {name="cardiac blood vessel endothelial cell on CELLxGENE CellGuide"} [Term] id: CL:0010007 name: His-Purkinje system cell def: "Any cell that is part of some His-Purkinje system." [FBC:Autogenerated] is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0004146 ! His-Purkinje system relationship: part_of UBERON:0004146 ! His-Purkinje system [Term] id: CL:0010008 name: cardiac endothelial cell def: "Any endothelial cell that is part of some heart." [FBC:Autogenerated] subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000115 ! endothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0010008" xsd:string {name="cardiac endothelial cell on CELLxGENE CellGuide"} [Term] id: CL:0010009 name: camera-type eye photoreceptor cell def: "Any photoreceptor cell that is part of some camera-type eye." [FBC:Autogenerated] synonym: "camera type eye photoreceptor cell" EXACT [] is_a: CL:0000287 ! eye photoreceptor cell is_a: CL:0009004 ! retinal cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of UBERON:0000966 {seeAlso="https://github.com/obophenotype/cell-ontology/issues/2245"} ! retina [Term] id: CL:0010012 name: cerebral cortex neuron def: "A CNS neuron of the cerebral cortex." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "cortical neuron" EXACT [] synonym: "neuron of cerebral cortex" EXACT [] xref: BTO:0004102 xref: FMA:84104 is_a: CL:0012001 ! neuron of the forebrain intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0000956 ! has soma location cerebral cortex relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: RO:0002100 UBERON:0000956 ! has soma location cerebral cortex property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0010012" xsd:string {name="cerebral cortex neuron on CELLxGENE CellGuide"} property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/1359" xsd:string [Term] id: CL:0010017 name: zygote def: "A zygote in a plant or an animal." [] xref: MESH:D015053 is_a: CL:0000000 ! cell relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 [Term] id: CL:0010020 name: cardiac glial cell def: "Any glial cell that is part of some heart." [FBC:Autogenerated] is_a: CL:0000125 ! glial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000125 ! glial cell intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart [Term] id: CL:0010021 name: cardiac myoblast def: "Any myoblast that develops into some cardiac muscle cell." [FBC:Autogenerated] xref: MESH:D032386 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000746 ! cardiac muscle cell relationship: develops_into CL:0000746 ! cardiac muscle cell [Term] id: CL:0010022 name: cardiac neuron def: "A neuron that has its soma in the heart." [PMID:12486170, PMID:29265764] comment: This term is used in 3 GO terms that were created as part of the heart development focus project. subset: cellxgene_subset is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:2000032 ! peripheral nervous system neuron intersection_of: RO:0002100 UBERON:0000948 ! has soma location heart relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: RO:0002100 UBERON:0000948 ! has soma location heart property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0010022" xsd:string {name="cardiac neuron on CELLxGENE CellGuide"} property_value: seeAlso "https://github.com/obophenotype/cell-ontology/pull/1488" xsd:string [Term] id: CL:0011001 name: spinal cord motor neuron def: "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [GOC:nv] subset: cellxgene_subset is_a: CL:0000100 {is_inferred="true"} ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: RO:0002100 UBERON:0002240 ! has soma location spinal cord relationship: RO:0002100 UBERON:0002240 ! has soma location spinal cord [Term] id: CL:0011007 name: paraxial cell def: "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites." [GOC:NV, PMID:11687492] synonym: "paraxial mesoderm cell" EXACT [] synonym: "presomitic mesoderm cell" NARROW [] synonym: "somitic mesoderm cell" EXACT [] is_a: CL:0000222 ! mesodermal cell intersection_of: CL:0000222 ! mesodermal cell intersection_of: part_of UBERON:0003059 ! presomitic mesoderm relationship: part_of UBERON:0003059 ! presomitic mesoderm [Term] id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0011012" xsd:string {name="neural crest cell on CELLxGENE CellGuide"} [Term] id: CL:0011013 name: motile sperm cell def: "A sperm cell that is cabaple of motion (motility)." [PMID:30612620] is_a: CL:0000019 ! sperm is_a: CL:0000219 ! motile cell intersection_of: CL:0000019 ! sperm intersection_of: capable_of GO:0097722 ! sperm motility relationship: capable_of GO:0097722 ! sperm motility relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011016 name: flagellated sperm cell def: "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion." [https://www.lexico.com/en/definition/flagellum, PMID:30612620] is_a: CL:0011013 ! motile sperm cell intersection_of: CL:0011013 ! motile sperm cell intersection_of: capable_of GO:0030317 ! flagellated sperm motility relationship: capable_of GO:0030317 ! flagellated sperm motility relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011019 name: mesothelial cell of epicardium def: "A mesothelial cell that is part of the epicardium." [] subset: cellxgene_subset is_a: CL:0000077 ! mesothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002348 ! epicardium relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: part_of UBERON:0002348 ! epicardium [Term] id: CL:0011021 name: fibroblast of upper back skin def: "A fibroblast that is part of upper back skin." [] is_a: CL:0011022 ! fibroblast of skin of back intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0009015 ! upper back skin relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: part_of UBERON:0009015 ! upper back skin [Term] id: CL:0011022 name: fibroblast of skin of back def: "A fibroblast that is part of skin of back." [] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001068 ! skin of back relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: part_of UBERON:0001068 ! skin of back [Term] id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] subset: cellxgene_subset is_a: CL:0000255 ! eukaryotic cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: develops_from CL:0000034 ! stem cell [Term] id: CL:0011027 name: skeletal muscle fibroblast def: "Any fibroblast that is part of skeletal muscle tissue." [https://orcid.org/0000-0001-6164-0667, PMID:28369879] subset: cellxgene_subset synonym: "skeleton muscle fibroblast" EXACT [] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:1001609 ! muscle fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0011027" xsd:string {name="skeletal muscle fibroblast on CELLxGENE CellGuide"} [Term] id: CL:0011030 name: dermal microvascular endothelial cell def: "Any microvascular endothelial cell that is part of the dermis." [BTO:0004574, CL:patterns/cellPartOfAnatomicalEntity] synonym: "dermal microvascular endothelium cell" EXACT [] synonym: "DMEC cell" EXACT [] is_a: CL:2000008 ! microvascular endothelial cell is_a: CL:2000010 ! dermis blood vessel endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0002067 ! dermis relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011101 name: chorionic trophoblast cell def: "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [GOC:NV] subset: cellxgene_subset is_a: CL:0000351 ! trophoblast cell intersection_of: CL:0000351 ! trophoblast cell intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: part_of UBERON:0003124 ! chorion membrane property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0011101" xsd:string {name="chorionic trophoblast cell on CELLxGENE CellGuide"} [Term] id: CL:0011108 name: colon epithelial cell def: "Epithelial cell that is part of the colon epithelium." [GOC:NV] subset: cellxgene_subset synonym: "colonic epithelial cell" EXACT [] is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000397 ! colonic epithelium relationship: part_of UBERON:0000397 ! colonic epithelium [Term] id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation relationship: capable_of GO:0030154 ! cell differentiation [Term] id: CL:0012001 name: neuron of the forebrain def: "A CNS neuron of the forebrain." [] subset: cellxgene_subset subset: human_reference_atlas synonym: "forebrain neuron" EXACT [] is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0001890 ! has soma location forebrain relationship: dc-contributor https://orcid.org/0000-0002-3837-8864 relationship: RO:0002100 UBERON:0001890 ! has soma location forebrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0017500 name: neutrophillic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain." [GOC:add] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0070046 ! bearer of neutrophillic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: RO:0000053 PATO:0070046 ! bearer of neutrophillic creation_date: 2010-05-25T01:36:34Z [Term] id: CL:0017502 name: acidophilic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain." [GOC:add] synonym: "eosinophilic" NARROW [] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0002418 ! bearer of acidophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: RO:0000053 PATO:0002418 ! bearer of acidophilic creation_date: 2009-12-22T04:23:25Z [Term] id: CL:0017503 name: basophilic cytoplasm def: "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0002094 ! bearer of basophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: RO:0000053 PATO:0002094 ! bearer of basophilic creation_date: 2009-12-22T04:24:54Z [Term] id: CL:0017504 name: polychromatophilic cytoplasm def: "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: RO:0000053 PATO:0070047 ! bearer of polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: RO:0000053 PATO:0070047 ! bearer of polychromatophilic creation_date: 2009-12-28T04:25:23Z [Term] id: CL:0019001 name: tracheobronchial serous cell def: "Any serous secreting cell that is part of the tracheobronchial epithelium." [] subset: added_for_HCA subset: cellxgene_subset synonym: "serous cell of tracheobronchial tree" EXACT [] is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000313 ! serous secreting cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: dcterms-date "2020-05-07T16:03:27Z" xsd:dateTime property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0019001" xsd:string {name="tracheobronchial serous cell on CELLxGENE CellGuide"} [Term] id: CL:0019002 name: tracheobronchial chondrocyte def: "Any chondrocyte that is part of the tracheobronchial tree." [] subset: added_for_HCA subset: human_reference_atlas synonym: "chondrocyte of tracheobronchial tree" EXACT [] is_a: CL:0000138 ! chondrocyte intersection_of: CL:0000138 ! chondrocyte intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: dcterms-date "2020-05-07T17:29:51Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0019018 name: blood vessel smooth muscle cell def: "A smooth muscle cell that is part of any blood vessel." [PMID:9108778] subset: cellxgene_subset subset: human_reference_atlas synonym: "smooth muscle cell of blood vessel" EXACT [] is_a: CL:0000359 ! vascular associated smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001981 ! blood vessel relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0001981 ! blood vessel property_value: dcterms-date "2020-07-21T12:42:48Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0019019 name: tracheobronchial smooth muscle cell def: "A smooth muscle cell that is part of the tracheobronchial tree." [PMID:10853867] comment: The marker set ACTA2, TAGLN can identify the Human cell type tracheobronchial smooth muscle cell in the lung with a confidence of 0.69 (NS-Forest FBeta value). {xref="https://doi.org/10.5281/zenodo.11165918"} subset: cellxgene_subset subset: human_reference_atlas synonym: "smooth muscle cell of tracheobronchial tree" EXACT [] is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0007196 ! tracheobronchial tree relationship: RO:0015004 CLM:1000056 ! has characterizing marker set property_value: dcterms-date "2020-07-21T12:50:22Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_0019019" xsd:string {name="tracheobronchial smooth muscle cell on CELLxGENE CellGuide"} [Term] id: CL:0019020 name: extrahepatic cholangiocyte def: "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes." [PMID:23720296] synonym: "large bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: part_of UBERON:0004822 ! extrahepatic bile duct epithelium relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0004822 ! extrahepatic bile duct epithelium property_value: dcterms-date "2020-09-03T12:24:24Z" xsd:dateTime [Term] id: CL:0019021 name: endothelial cell of periportal hepatic sinusoid def: "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid." [PMID:27423426] subset: cellxgene_subset synonym: "periportal hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "periportal LSEC" EXACT [PMID:28287163] xref: EFO:0010705 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: adjacent_to UBERON:0001279 ! portal triad relationship: adjacent_to UBERON:0001279 ! portal triad relationship: dc-contributor https://orcid.org/0000-0003-2034-601X property_value: dcterms-date "2020-09-09T13:56:47Z" xsd:dateTime [Term] id: CL:0019022 name: endothelial cell of pericentral hepatic sinusoid def: "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid." [PMID:27423426] subset: cellxgene_subset synonym: "central venous hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "pericentral LSEC" EXACT [PMID:28287163] xref: EFO:0010706 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: adjacent_to UBERON:0006841 ! central vein of liver relationship: adjacent_to UBERON:0006841 ! central vein of liver relationship: dc-contributor https://orcid.org/0000-0003-2034-601X property_value: dcterms-date "2020-09-10T12:38:29Z" xsd:dateTime [Term] id: CL:1000042 name: forebrain neuroblast def: "Any neuroblast (sensu Vertebrata) that is part of some forebrain." [FBC:Autogenerated] subset: cellxgene_subset is_a: CL:0000031 ! neuroblast (sensu Vertebrata) is_a: CL:0002319 ! neural cell intersection_of: CL:0000031 ! neuroblast (sensu Vertebrata) intersection_of: part_of UBERON:0001890 ! forebrain relationship: part_of UBERON:0001890 ! forebrain [Term] id: CL:1000090 name: pronephric nephron tubule epithelial cell def: "Any epithelial cell that is part of some pronephric nephron tubule." [FBC:Autogenerated] is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of UBERON:0005310 ! pronephric nephron tubule [Term] id: CL:1000123 name: metanephric nephron tubule epithelial cell def: "Any epithelial cell that is part of some metanephric nephron tubule." [FBC:Autogenerated] is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0005146 ! metanephric nephron tubule [Term] id: CL:1000222 name: stomach neuroendocrine cell def: "A specialised neuroendocrine cell located in the gastric mucosa that regulates digestive processes including acid secretion and gut motility. This cell stores hormones in large dense core vesicles and synaptic-like microvesicles." [PMID:15153415] synonym: "DES cell" BROAD [PMID:15153415] synonym: "diffuse endocrine system cell" BROAD [PMID:15153415] is_a: CL:0000165 ! neuroendocrine cell is_a: CL:1001517 ! stomach enteroendocrine cell intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0001276 ! epithelium of stomach relationship: capable_of GO:0046717 ! acid secretion relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: CL:1000223 name: pulmonary neuroendocrine cell def: "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury." [doi:10.3109/01902148209069653, doi:10.7554/eLife.78216, PMID:33355253] comment: The marker set CHGA, GRP can identify the Human cell type pulmonary neuroendocrine cell in the lung with a confidence of 0.94 (NS-Forest FBeta value). {xref="https://doi.org/10.5281/zenodo.11165918"} subset: cellxgene_subset subset: human_reference_atlas synonym: "lung neuroendocrine cell" EXACT [PMID:15018448] synonym: "PNEC" RELATED OMO:0003000 [PMID:33355253] is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000098 ! sensory epithelial cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0000206 ! chemoreceptor cell is_a: CL:0000458 ! serotonin secreting cell is_a: CL:1000272 ! lung secretory cell intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0002048 ! lung relationship: capable_of GO:0070483 ! detection of hypoxia relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_part GO:0031045 ! dense core granule relationship: RO:0015004 CLM:1000043 ! has characterizing marker set property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000223" xsd:string {name="pulmonary neuroendocrine cell on CELLxGENE CellGuide"} [Term] id: CL:1000272 name: lung secretory cell def: "Any secretory cell that is part of some lung." [FBC:Autogenerated] subset: cellxgene_subset is_a: CL:0000151 ! secretory cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: CL:1000274 name: trophectodermal cell def: "An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange." [PMID:22918806] synonym: "trophectoderm cell" EXACT [] is_a: CL:0000349 ! extraembryonic cell intersection_of: CL:0000349 ! extraembryonic cell intersection_of: part_of UBERON:0004345 ! trophectoderm relationship: develops_into CL:0000351 ! trophoblast cell relationship: part_of UBERON:0004345 ! trophectoderm [Term] id: CL:1000275 name: smooth muscle cell of small intestine def: "A smooth muscle cell that is part of the small intestine." [GOC:tfm] subset: cellxgene_subset synonym: "non-striated muscle fiber of small intestine" EXACT [FMA:15050] xref: FMA:15050 is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0002108 ! small intestine property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000275" xsd:string {name="smooth muscle cell of small intestine on CELLxGENE CellGuide"} [Term] id: CL:1000276 name: smooth muscle fiber of duodenum def: "A smooth muscle cell that is part of the duodenum." [GOC:tfm] synonym: "non-striated muscle fiber of duodenum" EXACT [FMA:15058] xref: FMA:15058 is_a: CL:1000275 {is_inferred="true"} ! smooth muscle cell of small intestine intersection_of: CL:1000275 ! smooth muscle cell of small intestine intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0001902 ! epithelium of small intestine relationship: part_of UBERON:0002114 ! duodenum [Term] id: CL:1000279 name: smooth muscle cell of large intestine def: "A smooth muscle cell that is part of the large intestine." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "non-striated muscle fiber of large intestine" EXACT [FMA:15653] xref: FMA:15653 is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0000059 ! large intestine property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000280 name: smooth muscle cell of colon def: "A smooth muscle cell that is part of the colon." [GOC:tfm] synonym: "non-striated muscle fiber of colon" EXACT [FMA:15663] xref: FMA:15663 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001278 ! epithelium of large intestine [Term] id: CL:1000285 name: smooth muscle cell of sigmoid colon def: "A smooth muscle cell that is part of the sigmoid colon." [GOC:tfm] synonym: "non-striated muscle fiber of sigmoid colon" EXACT [FMA:17521] xref: FMA:17521 is_a: CL:1000280 {is_inferred="true"} ! smooth muscle cell of colon intersection_of: CL:1000280 ! smooth muscle cell of colon intersection_of: part_of UBERON:0001159 ! sigmoid colon relationship: part_of UBERON:0001159 ! sigmoid colon [Term] id: CL:1000286 name: smooth muscle cell of rectum def: "A smooth muscle cell that is part of the rectum." [GOC:tfm] synonym: "non-striated muscle fiber of rectum" EXACT [FMA:17522] synonym: "smooth muscle fiber of rectum" EXACT [] xref: FMA:17522 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001278 ! epithelium of large intestine [Term] id: CL:1000296 name: epithelial cell of urethra def: "An epithelial cell that is part of the urethra." [GOC:tfm] subset: cellxgene_subset xref: FMA:256165 is_a: CL:0000066 ! epithelial cell is_a: CL:1001320 ! urethra cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000057 ! urethra property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000296" xsd:string {name="epithelial cell of urethra on CELLxGENE CellGuide"} [Term] id: CL:1000298 name: mesothelial cell of dura mater def: "A mesothelial cell that is part of the dura mater." [GOC:tfm] synonym: "squamous mesothelial cell of dura mater" EXACT [FMA:256516] xref: FMA:256516 is_a: CL:0000077 ! mesothelial cell is_a: CL:0002319 ! neural cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002363 ! dura mater relationship: part_of UBERON:0002363 ! dura mater [Term] id: CL:1000303 name: fibroblast of areolar connective tissue def: "A fibroblast that is part of the areolar connective tissue." [GOC:tfm] xref: FMA:261279 is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0006815 ! areolar connective tissue relationship: part_of UBERON:0006815 ! areolar connective tissue [Term] id: CL:1000306 name: fibroblast of tunica adventitia of artery def: "A fibroblast that is part of the tunica adventitia of artery." [GOC:tfm] xref: FMA:261285 is_a: CL:4052030 ! adventitial fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0007240 ! tunica adventitia of artery relationship: part_of UBERON:0007240 ! tunica adventitia of artery [Term] id: CL:1000307 name: fibroblast of dense regular elastic tissue def: "A fibroblast that is part of the dense regular elastic tissue." [GOC:tfm] xref: FMA:261287 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0007846 ! dense regular connective tissue relationship: part_of UBERON:0002521 ! elastic tissue relationship: part_of UBERON:0007846 ! dense regular connective tissue [Term] id: CL:1000309 name: epicardial adipocyte def: "An adipocyte that is part of the epicardial fat." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "adipocyte of epicardial fat" EXACT [FMA:261293] synonym: "epicardial fat cell" EXACT [FMA:261293] xref: FMA:261293 is_a: CL:0000136 ! adipocyte is_a: CL:0002494 ! cardiocyte relationship: part_of UBERON:0002348 ! epicardium property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000309" xsd:string {name="epicardial adipocyte on CELLxGENE CellGuide"} [Term] id: CL:1000310 name: adipocyte of epicardial fat of right ventricle def: "An adipocyte that is part of the epicardial fat of right ventricle." [GOC:tfm] synonym: "epicardial adipocyte of right ventricle" EXACT [FMA:261297] synonym: "epicardial fat cell of right ventricle" EXACT [FMA:261297] xref: FMA:261297 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0002080 ! heart right ventricle [Term] id: CL:1000311 name: adipocyte of epicardial fat of left ventricle def: "An adipocyte that is part of the epicardial fat of left ventricle." [GOC:tfm] subset: cellxgene_subset synonym: "epicardial adipocyte of left ventricle" EXACT [FMA:261300] synonym: "epicardial fat cell of left ventricle" EXACT [FMA:261300] xref: FMA:261300 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 ! heart left ventricle property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000311" xsd:string {name="adipocyte of epicardial fat of left ventricle on CELLxGENE CellGuide"} [Term] id: CL:1000330 name: serous cell of epithelium of trachea def: "A serous secreting cell that is part of the epithelium of trachea." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:263078 is_a: CL:0019001 ! tracheobronchial serous cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:0001901 ! epithelium of trachea relationship: part_of UBERON:0001901 ! epithelium of trachea property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000330" xsd:string {name="serous cell of epithelium of trachea on CELLxGENE CellGuide"} [Term] id: CL:1000331 name: serous cell of epithelium of bronchus def: "A serous secreting cell that is part of the epithelium of bronchus." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:263080 is_a: CL:0019001 ! tracheobronchial serous cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:0002031 ! epithelium of bronchus relationship: part_of UBERON:0002031 ! epithelium of bronchus property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000331" xsd:string {name="serous cell of epithelium of bronchus on CELLxGENE CellGuide"} [Term] id: CL:1000361 name: transitional myocyte of interatrial septum def: "A transitional myocyte that is part of the interatrial septum." [GOC:tfm] xref: FMA:263152 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002085 ! interatrial septum relationship: part_of UBERON:0002085 ! interatrial septum [Term] id: CL:1000362 name: transitional myocyte of interventricular septum def: "A transitional myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263154 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000376 name: Purkinje myocyte of interventricular septum def: "A Purkinje myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263182 is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000398 name: endothelial cell of hepatic sinusoid def: "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates." [GOC:tfm, PMID:3926620] subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte of hepatic sinusoid" EXACT [FMA:62911] synonym: "liver sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "LSEC" EXACT [PMID:30348985] xref: BTO:000125 xref: FMA:62911 is_a: CL:0000666 ! fenestrated endothelial cell is_a: CL:0002262 ! endothelial cell of sinusoid intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001281 ! hepatic sinusoid relationship: part_of UBERON:0001281 ! hepatic sinusoid property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000398" xsd:string {name="endothelial cell of hepatic sinusoid on CELLxGENE CellGuide"} [Term] id: CL:1000409 name: myocyte of sinoatrial node def: "A muscle cell that is part of the sinoatrial node." [FMA:67102, GOC:tfm] subset: cellxgene_subset synonym: "SA nodal myocyte" EXACT [FMA:67102] synonym: "SA node cardiac muscle cell" EXACT [GOC:pr] synonym: "sinoatrial node cell" EXACT [GOC:pr] synonym: "sinoatrial node myocyte" EXACT [] synonym: "sinuatrial node myocyte" EXACT [FMA:67102] xref: FMA:67102 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002351 ! sinoatrial node relationship: part_of UBERON:0002351 ! sinoatrial node [Term] id: CL:1000410 name: myocyte of atrioventricular node def: "A muscle cell that is part of the atrioventricular node." [FMA:67106, GOC:tfm] synonym: "atrioventricular node cell" EXACT [GOC:pr] synonym: "atrioventricular node myocyte" EXACT [FMA:67106] synonym: "AV nodal myocyte" EXACT [FMA:67106] synonym: "AV node cardiac muscle cell" EXACT [GOC:pr] synonym: "AV node cell" EXACT [GOC:pr] xref: FMA:67106 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002352 ! atrioventricular node relationship: part_of UBERON:0002352 ! atrioventricular node [Term] id: CL:1000412 name: endothelial cell of arteriole def: "An endothelial cell that is part of the arteriole." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67760 xref: KUPO:0001097 is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001980 ! arteriole relationship: part_of UBERON:0001980 ! arteriole property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000413 name: endothelial cell of artery def: "A blood vessel endothelial cell that is part of an arterial endothelium." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "arterial endothelial cell" EXACT [] xref: BTO:0004758 xref: FMA:67761 xref: KUPO:0001095 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0001917 ! endothelium of artery property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000413" xsd:string {name="endothelial cell of artery on CELLxGENE CellGuide"} [Term] id: CL:1000414 name: endothelial cell of venule def: "An endothelial cell that is part of the venule." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67762 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0001979 ! venule relationship: part_of UBERON:0001979 ! venule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000415 name: epithelial cell of gallbladder def: "An epithelial cell that is part of the gallbladder." [GOC:tfm] xref: FMA:67780 is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: CL:1000428 name: stem cell of epidermis def: "A somatic stem cell that is part of the epidermis." [GOC:tfm] subset: cellxgene_subset synonym: "epidermal stem cell" EXACT [FMA:70541] xref: FMA:70541 xref: ZFA:0007122 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000723 {is_inferred="true"} ! somatic stem cell intersection_of: CL:0000723 ! somatic stem cell intersection_of: part_of UBERON:0001003 ! skin epidermis relationship: part_of UBERON:0001003 ! skin epidermis property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000428" xsd:string {name="stem cell of epidermis on CELLxGENE CellGuide"} [Term] id: CL:1000434 name: epithelial cell of external acoustic meatus def: "An epithelial cell that is part of the external acoustic meatus." [GOC:tfm] xref: FMA:70555 is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001352 ! external acoustic meatus relationship: part_of UBERON:0001352 ! external acoustic meatus [Term] id: CL:1000443 name: ciliary muscle cell def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm] subset: cellxgene_subset subset: eye_upper_slim synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610] xref: FMA:70610 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001775 ! ciliary body relationship: part_of UBERON:0001775 ! ciliary body property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000443" xsd:string {name="ciliary muscle cell on CELLxGENE CellGuide"} [Term] id: CL:1000444 name: mesothelial cell of anterior chamber of eye def: "A mesothelial cell that is part of the anterior chamber of eyeball." [GOC:tfm] xref: FMA:70615 is_a: CL:0000077 ! mesothelial cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001766 ! anterior chamber of eyeball relationship: part_of UBERON:0001766 ! anterior chamber of eyeball [Term] id: CL:1000449 name: epithelial cell of nephron def: "An epithelial cell that is part of the nephron." [GOC:tfm] subset: cellxgene_subset xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001285 ! nephron relationship: part_of UBERON:0001285 ! nephron property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000449" xsd:string {name="epithelial cell of nephron on CELLxGENE CellGuide"} [Term] id: CL:1000454 name: kidney collecting duct epithelial cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982] xref: FMA:70982 xref: KUPO:0001059 is_a: CL:0000072 {is_inferred="true"} ! non-branched duct epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1001225 {is_inferred="true"} ! kidney collecting duct cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000454" xsd:string {name="kidney collecting duct epithelial cell on CELLxGENE CellGuide"} [Term] id: CL:1000456 name: mesothelial cell of parietal peritoneum def: "A mesothelial cell that is part of the parietal peritoneum." [GOC:tfm] xref: FMA:72142 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001366 ! parietal peritoneum relationship: part_of UBERON:0001366 ! parietal peritoneum [Term] id: CL:1000457 name: mesothelial cell of visceral peritoneum def: "A mesothelial cell that is part of the visceral peritoneum." [GOC:tfm] subset: human_reference_atlas xref: FMA:72143 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001178 ! visceral peritoneum relationship: part_of UBERON:0001178 ! visceral peritoneum property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000478 name: transitional myocyte of sinoatrial node def: "A transitional myocyte that is part of the sinoatrial node." [GOC:tfm] synonym: "transitinal myocyte of sinuatrial node" EXACT [] xref: FMA:83384 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:1000409 ! myocyte of sinoatrial node intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002351 ! sinoatrial node [Term] id: CL:1000479 name: Purkinje myocyte of atrioventricular node def: "A Purkinje myocyte that is part of the atrioventricular node." [GOC:tfm] xref: FMA:83386 is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte is_a: CL:1000410 ! myocyte of atrioventricular node intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: part_of UBERON:0002352 ! atrioventricular node [Term] id: CL:1000482 name: myocardial endocrine cell of interventricular septum def: "A myocardial endocrine cell that is part of the interventricular septum." [GOC:tfm] xref: FMA:83390 is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000488 name: cholangiocyte def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." [GOC:tfm, PMID:16550043, PMID:18356246] subset: cellxgene_subset synonym: "epithelial cell of bile duct" EXACT [] xref: FMA:86481 xref: ZFA:0009397 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000069 {is_inferred="true"} ! branched duct epithelial cell intersection_of: CL:0000069 ! branched duct epithelial cell intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0002394 ! bile duct relationship: develops_from CL:0005026 ! hepatoblast relationship: part_of UBERON:0002394 ! bile duct property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000488" xsd:string {name="cholangiocyte on CELLxGENE CellGuide"} [Term] id: CL:1000490 name: mesothelial cell of peritoneum def: "A mesothelial cell that is part of the peritoneum." [GOC:tfm] synonym: "peritoneal mesothelial cell" EXACT [FMA:86736] xref: FMA:86736 is_a: CL:0000077 ! mesothelial cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002358 ! peritoneum relationship: part_of UBERON:0002358 ! peritoneum [Term] id: CL:1000491 name: mesothelial cell of pleura def: "A mesothelial cell that is part of the pleura." [GOC:tfm] subset: cellxgene_subset synonym: "pleural mesothelial cell" EXACT [FMA:86737] xref: FMA:86737 is_a: CL:0000077 ! mesothelial cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0000977 ! pleura relationship: part_of UBERON:0000977 ! pleura property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000491" xsd:string {name="mesothelial cell of pleura on CELLxGENE CellGuide"} [Term] id: CL:1000492 name: mesothelial cell of parietal pleura def: "A mesothelial cell that is part of the parietal pleura." [GOC:tfm] xref: FMA:86738 is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002400 ! parietal pleura relationship: part_of UBERON:0002400 ! parietal pleura [Term] id: CL:1000493 name: mesothelial cell of visceral pleura def: "A mesothelial cell that is part of the visceral pleura." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas xref: FMA:86739 is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002401 ! visceral pleura relationship: part_of UBERON:0002401 ! visceral pleura property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000493" xsd:string {name="mesothelial cell of visceral pleura on CELLxGENE CellGuide"} [Term] id: CL:1000494 name: nephron tubule epithelial cell def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm] comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. subset: cellxgene_subset synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004810 ! nephron tubule epithelium relationship: part_of UBERON:0004810 ! nephron tubule epithelium [Term] id: CL:1000497 name: kidney cell def: "A cell that is part of a kidney." [] subset: cellxgene_subset xref: KUPO:0001010 xref: ZFA:0009389 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney [Term] id: CL:1000500 name: kidney interstitial cell def: "A cell that is part of kidney interstitium." [] subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001013 xref: ZFA:0009390 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:1000497 ! kidney cell is_a: CL:4030031 ! interstitial cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0005215 ! kidney interstitium [Term] id: CL:1000504 name: kidney medulla cell def: "A cell that is part of a renal medulla." [PMID:22343825] xref: KUPO:0001017 xref: ZFA:0009391 {sssom:mapping_justification="https://w3id.org/semapv/vocab/UnspecifiedMatching"} is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0000362 ! renal medulla relationship: part_of UBERON:0000362 ! renal medulla [Term] id: CL:1000505 name: kidney pelvis cell def: "A cell that is part of a renal pelvis." [] subset: kidney_upper_slim xref: KUPO:0001018 is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: CL:1000507 name: kidney tubule cell def: "A cell that is part of a nephron tubule." [] subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001020 is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0001231 ! nephron tubule [Term] id: CL:1000546 name: kidney medulla collecting duct epithelial cell def: "An epithelial cell that is part of a renal medulla collecting duct." [] subset: kidney_upper_slim xref: KUPO:0001060 is_a: CL:1000454 ! kidney collecting duct epithelial cell is_a: CL:1000504 ! kidney medulla cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0005185 ! renal medulla collecting duct relationship: part_of UBERON:0005185 ! renal medulla collecting duct [Term] id: CL:1000549 name: kidney cortex collecting duct epithelial cell def: "An epithelial cell that is part of a cortical collecting duct." [] subset: cellxgene_subset xref: KUPO:0001063 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000454 ! kidney collecting duct epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004203 ! cortical collecting duct relationship: part_of UBERON:0004203 ! cortical collecting duct [Term] id: CL:1000600 name: lower urinary tract cell def: "Any cell that is part of some lower urinary tract." [FBC:Autogenerated] xref: KUPO:0001115 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001556 ! lower urinary tract relationship: part_of UBERON:0001556 ! lower urinary tract [Term] id: CL:1000601 name: ureteral cell def: "Any cell that is part of some ureter." [FBC:Autogenerated] xref: KUPO:0001116 is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0000056 ! ureter [Term] id: CL:1000606 name: kidney nerve cell def: "Any neuron that has its soma located in some kidney." [FBC:Autogenerated] xref: KUPO:0001015 is_a: CL:1000500 ! kidney interstitial cell is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0002113 ! has soma location kidney relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: RO:0002100 UBERON:0002113 ! has soma location kidney [Term] id: CL:1000681 name: kidney cortex interstitial cell def: "A cell that is part of an interstitial compartment of a renal cortex." [PMID:18575881] xref: KUPO:0001091 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000500 {is_inferred="true"} ! kidney interstitial cell intersection_of: CL:1000500 ! kidney interstitial cell intersection_of: part_of UBERON:0005270 ! renal cortex interstitium relationship: part_of UBERON:0005270 ! renal cortex interstitium [Term] id: CL:1000682 name: kidney medulla interstitial cell def: "A cell that is part of an interstitum of a renal medulla." [PMID:21359760] xref: KUPO:0001092 is_a: CL:1000500 {is_inferred="true"} ! kidney interstitial cell is_a: CL:1000504 {is_inferred="true"} ! kidney medulla cell intersection_of: CL:1000500 ! kidney interstitial cell intersection_of: part_of UBERON:0005211 ! renal medulla interstitium relationship: part_of UBERON:0005211 ! renal medulla interstitium [Term] id: CL:1000692 name: kidney interstitial fibroblast def: "A fibroblast that is part of an interstitial compartment of a kidney." [PMID:10559635] subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001102 is_a: CL:0000057 ! fibroblast is_a: CL:1000500 ! kidney interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005215 ! kidney interstitium property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000692" xsd:string {name="kidney interstitial fibroblast on CELLxGENE CellGuide"} [Term] id: CL:1000702 name: kidney pelvis smooth muscle cell def: "Any smooth muscle cell that is part of some kidney pelvis smooth muscle." [FBC:Autogenerated] xref: KUPO:0001113 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1000505 {is_inferred="true"} ! kidney pelvis cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0004227 ! kidney pelvis smooth muscle relationship: part_of UBERON:0004227 ! kidney pelvis smooth muscle [Term] id: CL:1000708 name: ureter adventitial cell def: "Any ureteral cell that is part of some adventitia of ureter." [FBC:Autogenerated] subset: human_reference_atlas xref: KUPO:0001119 is_a: CL:0000115 ! endothelial cell is_a: CL:0002503 ! adventitial cell is_a: CL:1000601 {is_inferred="true"} ! ureteral cell intersection_of: CL:1000601 ! ureteral cell intersection_of: part_of UBERON:0001252 ! adventitia of ureter relationship: part_of UBERON:0001252 ! adventitia of ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000714 name: kidney cortex collecting duct principal cell def: "Any renal principal cell that is part of some cortical collecting duct." [FBC:Autogenerated] subset: human_reference_atlas xref: KUPO:0001130 is_a: CL:1000549 {is_inferred="true"} ! kidney cortex collecting duct epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell intersection_of: CL:0005009 ! renal principal cell intersection_of: part_of UBERON:0004203 ! cortical collecting duct property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000854 name: kidney blood vessel cell def: "A blood vessel cell that is part of a kidney." [PMID:34843404] xref: KUPO:0001014 is_a: CL:1000504 {is_inferred="true"} ! kidney medulla cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0003517 ! kidney blood vessel relationship: part_of UBERON:0003517 ! kidney blood vessel relationship: participates_in GO:0008015 ! blood circulation [Term] id: CL:1000891 name: kidney arterial blood vessel cell def: "Any kidney blood vessel cell that is part of some kidney arterial blood vessel." [FBC:Autogenerated] subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001029 is_a: CL:1000854 {is_inferred="true"} ! kidney blood vessel cell intersection_of: CL:1000854 ! kidney blood vessel cell intersection_of: part_of UBERON:0003644 ! kidney arterial blood vessel relationship: part_of UBERON:0003644 ! kidney arterial blood vessel [Term] id: CL:1000892 name: kidney capillary endothelial cell def: "An endothelial cell that is part of the capillary of the kidney." [] subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001030 is_a: CL:0002144 ! capillary endothelial cell is_a: CL:1000854 ! kidney blood vessel cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0003527 ! kidney capillary relationship: part_of UBERON:0003527 ! kidney capillary property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1000892" xsd:string {name="kidney capillary endothelial cell on CELLxGENE CellGuide"} [Term] id: CL:1000893 name: kidney venous blood vessel cell def: "Any kidney blood vessel cell that is part of some renal vein." [FBC:Autogenerated] subset: kidney_upper_slim xref: KUPO:0001031 is_a: CL:1000854 {is_inferred="true"} ! kidney blood vessel cell intersection_of: CL:1000854 ! kidney blood vessel cell intersection_of: part_of UBERON:0001140 ! renal vein relationship: part_of UBERON:0001140 ! renal vein [Term] id: CL:1000979 name: ureter smooth muscle cell def: "Any smooth muscle cell that is part of some muscular coat of ureter." [FBC:Autogenerated] subset: human_reference_atlas xref: KUPO:0001118 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1000601 {is_inferred="true"} ! ureteral cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0006855 ! muscular coat of ureter relationship: part_of UBERON:0006855 ! muscular coat of ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001045 name: kidney cortex artery cell def: "Any kidney arterial blood vessel cell that is part of some renal cortex artery." [FBC:Autogenerated] subset: cellxgene_subset xref: KUPO:0001077 is_a: CL:0002681 ! kidney cortical cell is_a: CL:1000891 ! kidney arterial blood vessel cell intersection_of: CL:1000891 ! kidney arterial blood vessel cell intersection_of: part_of UBERON:0005268 ! renal cortex artery relationship: part_of UBERON:0005268 ! renal cortex artery [Term] id: CL:1001052 name: kidney cortex vein cell def: "Any kidney venous blood vessel cell that is part of some renal cortex vein." [FBC:Autogenerated] xref: KUPO:0001084 is_a: CL:0002681 ! kidney cortical cell is_a: CL:1000893 {is_inferred="true"} ! kidney venous blood vessel cell intersection_of: CL:1000893 ! kidney venous blood vessel cell intersection_of: part_of UBERON:0005269 ! renal cortex vein relationship: part_of UBERON:0005269 ! renal cortex vein [Term] id: CL:1001225 name: kidney collecting duct cell def: "A cell that is part of a collecting duct of renal tubule." [] subset: cellxgene_subset xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000497 ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: CL:1001319 name: bladder cell def: "Any cell that is part of some urinary bladder." [FBC:Autogenerated] subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001120 is_a: CL:1000600 ! lower urinary tract cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 ! urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001320 name: urethra cell def: "Any cell that is part of some urethra." [FBC:Autogenerated] xref: KUPO:0001123 is_a: CL:1000600 ! lower urinary tract cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: CL:1001431 name: kidney collecting duct principal cell def: "Any renal principal cell that is part of some collecting duct of renal tubule." [FBC:Autogenerated] subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001128 is_a: CL:0005009 {is_inferred="true"} ! renal principal cell is_a: CL:1000454 ! kidney collecting duct epithelial cell intersection_of: CL:0005009 ! renal principal cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1001431" xsd:string {name="kidney collecting duct principal cell on CELLxGENE CellGuide"} [Term] id: CL:1001433 name: epithelial cell of exocrine pancreas def: "An epithelial cell of the exocrine pancreas." [GOC:tfm] subset: cellxgene_subset subset: human_reference_atlas synonym: "exocrine pancreas cell" EXACT [] xref: FMA:70986 is_a: CL:0000083 ! epithelial cell of pancreas intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0000017 ! exocrine pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001516 name: intestinal enteroendocrine cell def: "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract." [MP:0010802] subset: cellxgene_subset is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0001277 ! intestinal epithelium relationship: develops_from CL:4052006 ! intestinal enteroendocrine progenitor relationship: develops_from UBERON:0000160 ! intestine relationship: develops_from UBERON:0001007 ! digestive system relationship: develops_from UBERON:0001242 ! intestinal mucosa relationship: develops_from UBERON:0001262 ! wall of intestine relationship: develops_from UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0001983 ! crypt of Lieberkuhn relationship: develops_from UBERON:0005409 ! alimentary part of gastrointestinal system relationship: develops_from UBERON:0011184 ! epithelium of crypt of Lieberkuhn relationship: directly_develops_from CL:4052006 ! intestinal enteroendocrine progenitor property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1001516" xsd:string {name="intestinal enteroendocrine cell on CELLxGENE CellGuide"} [Term] id: CL:1001517 name: stomach enteroendocrine cell def: "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach." [MP:0010803] is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0002178 ! epithelial cell of stomach intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach [Term] id: CL:1001567 name: lung endothelial cell def: "Any endothelial cell of vascular tree that is part of some lung." [FBC:Autogenerated] subset: cellxgene_subset synonym: "endothelial cell of lung" RELATED [] synonym: "pulmonary vessel endothelial cell" RELATED [] is_a: CL:0002139 ! endothelial cell of vascular tree intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0000102 ! lung vasculature [Term] id: CL:1001568 name: pulmonary artery endothelial cell def: "Any endothelial cell of vascular tree that is part of some pulmonary artery." [FBC:Autogenerated] subset: cellxgene_subset subset: human_reference_atlas synonym: "PAEC cell" RELATED [BTO:0001141] xref: BTO:0001141 is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: part_of UBERON:0005317 ! pulmonary artery endothelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001572 name: colon endothelial cell def: "A vascular endothelial cell found in colon blood vessels." [https://orcid.org/0000-0001-5208-3432, NPX:PDR] subset: cellxgene_subset synonym: "colon endothelial cells" RELATED OMO:0003004 [CALOHA:TS-2397] synonym: "colonic endothelial cell" RELATED [CALOHA:TS-2397] xref: CALOHA:TS-2397 is_a: CL:0000131 ! gut endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0013695 ! colon endothelium [Term] id: CL:1001573 name: nasopharyngeal epithelial cell def: "Cell of the nasopharyngeal epithelium." [NPX:PDR] synonym: "nasopharynx respiratory epithelial cells" RELATED [CALOHA:TS-2398] xref: CALOHA:TS-2398 is_a: CL:0002251 ! epithelial cell of alimentary canal is_a: CL:0002631 ! epithelial cell of upper respiratory tract intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001951 ! epithelium of nasopharynx [Term] id: CL:1001575 name: uterine cervix squamous cell def: "Squamous cell of uterine cervix epithelium." [NPX:PDR] synonym: "cervix squamous cell" RELATED [CALOHA:TS-1251] synonym: "cervix squamous epithelial cell" RELATED [CALOHA:TS-1251] synonym: "cervix, uterine squamous epithelial cells" RELATED [CALOHA:TS-1251] synonym: "uterine cervix squamous epithelial cell" RELATED [CALOHA:TS-1251] synonym: "uterine cervix squamous epithelial cells" RELATED [CALOHA:TS-1251] xref: CALOHA:TS-1251 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002535 ! epithelial cell of cervix intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0000002 ! uterine cervix [Term] id: CL:1001576 name: oral mucosa squamous cell def: "Squamous cell of oral epithelium." [NPX:PDR] subset: cellxgene_subset synonym: "oral cavity mucosa squamous cell" RELATED [CALOHA:TS-1252] synonym: "oral cavity mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252] synonym: "oral mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252] synonym: "oral mucosa squamous epithelial cells" RELATED [CALOHA:TS-1252] xref: CALOHA:TS-1252 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0002424 ! oral epithelium relationship: part_of UBERON:0002424 ! oral epithelium [Term] id: CL:1001578 name: vagina squamous cell def: "Squamous cell of vaginal epithelium." [NPX:PDR] synonym: "vagina squamous epithelial cell" RELATED [CALOHA:TS-1254] synonym: "vagina squamous epithelial cells" RELATED [CALOHA:TS-1254] synonym: "vaginal squamous cell" RELATED [CALOHA:TS-1254] synonym: "vaginal squamous epithelial cell" RELATED [CALOHA:TS-1254] xref: CALOHA:TS-1254 is_a: CL:0000076 ! squamous epithelial cell intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0000996 ! vagina relationship: part_of UBERON:0001344 ! epithelium of vagina [Term] id: CL:1001579 name: cerebral cortex glial cell def: "Glial cell of cerebral cortex." [NPX:PDR] synonym: "brain cortex glial cell" RELATED [CALOHA:TS-1256] synonym: "cerebral cortex glial cells" RELATED [CALOHA:TS-1256] synonym: "cerebrum cortex glial cell" RELATED [CALOHA:TS-1256] xref: CALOHA:TS-1256 is_a: CL:0000125 ! glial cell intersection_of: CL:0000125 ! glial cell intersection_of: part_of UBERON:0000956 ! cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex [Term] id: CL:1001587 name: uterine cervix secretory cell def: "Glandular cell of uterine cervix epithelium." [NPX:PDR] synonym: "cervix glandular cell" RELATED [CALOHA:TS-1273] synonym: "cervix, uterine glandular cell" RELATED [CALOHA:TS-1273] synonym: "cervix, uterine glandular cells" RELATED [CALOHA:TS-1273] synonym: "uterine cervix glandular cell" RELATED [] xref: CALOHA:TS-1273 is_a: CL:0002535 ! epithelial cell of cervix is_a: CL:1001591 ! oviduct secretory cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: part_of UBERON:0000002 ! uterine cervix [Term] id: CL:1001588 name: colon glandular cell def: "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] synonym: "colon glandular cells" RELATED [CALOHA:TS-1274] xref: CALOHA:TS-1274 is_a: CL:0002658 ! glandular cell of the large intestine is_a: CL:0011108 ! colon epithelial cell intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0001155 ! colon [Term] id: CL:1001589 name: duodenum secretory cell def: "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell." [NPX:PDR] synonym: "duodenum glandular cells" NARROW [CALOHA:TS-1275] xref: CALOHA:TS-1275 is_a: CL:1001598 ! small intestine secretory cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0008346 ! duodenal epithelium [Term] id: CL:1001590 name: epididymis secretory cell def: "Glandular cell of epididymal epithelium." [NPX:PDR] synonym: "epididymal glandular cell" RELATED [CALOHA:TS-1276] synonym: "epididymis glandular cell" RELATED [CALOHA:TS-1276] xref: CALOHA:TS-1276 is_a: CL:0000068 ! duct epithelial cell is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: part_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0004544 ! epididymis epithelium [Term] id: CL:1001591 name: oviduct secretory cell def: "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." [HPA:HPA, NPX:PDR] synonym: "fallopian tube glandular cell" RELATED [CALOHA:TS-1277] synonym: "fallopian tube glandular cells" RELATED [CALOHA:TS-1277] synonym: "oviduct glandular cell" RELATED [] synonym: "uterine tube glandular cell" RELATED [CALOHA:TS-1277] xref: CALOHA:TS-1277 is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: part_of UBERON:0000993 ! oviduct relationship: part_of UBERON:0004804 ! oviduct epithelium [Term] id: CL:1001592 name: gallbladder glandular cell def: "Glandular cell of gallbladder epithelium." [NPX:PDR] synonym: "gall bladder glandular cell" EXACT [FMA:7202] synonym: "gall bladder glandular cells" RELATED [CALOHA:TS-1278] synonym: "gallbladder glandular cells" RELATED [CALOHA:TS-1278] xref: CALOHA:TS-1278 is_a: CL:0000150 ! glandular secretory epithelial cell is_a: CL:1000415 ! epithelial cell of gallbladder intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002029 ! epithelium of gall bladder [Term] id: CL:1001595 name: rectum glandular cell def: "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] synonym: "rectal glandular cell" RELATED [CALOHA:TS-1281] synonym: "rectum glandular cells" RELATED [CALOHA:TS-1281] xref: CALOHA:TS-1281 is_a: CL:0002658 ! glandular cell of the large intestine intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0003354 ! epithelium of rectum [Term] id: CL:1001597 name: seminal vesicle glandular cell def: "Glandular cell of seminal vesicle epithelium." [NPX:PDR] subset: cellxgene_subset synonym: "seminal vesicle glandular cells" RELATED [CALOHA:TS-1283] xref: CALOHA:TS-1283 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000150 ! glandular secretory epithelial cell intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: part_of UBERON:0004805 ! seminal vesicle epithelium property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1001597" xsd:string {name="seminal vesicle glandular cell on CELLxGENE CellGuide"} [Term] id: CL:1001598 name: small intestine secretory cell def: "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." [NCI_Thesaurus:Small_Intestinal_Glandular_Cell, NPX:PDR] synonym: "small bowel glandular cell" RELATED [CALOHA:TS-1286] synonym: "small intestinal glandular cell" NARROW [CALOHA:TS-1286] synonym: "small intestine glandular cells" RELATED [CALOHA:TS-1286] xref: CALOHA:TS-1286 xref: FMA:86928 is_a: CL:0002254 ! epithelial cell of small intestine is_a: CL:1100001 ! secretory epithelial cell intersection_of: CL:1100001 ! secretory epithelial cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001902 ! epithelium of small intestine [Term] id: CL:1001599 name: pancreas exocrine glandular cell def: "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." [HPA:HPA, NPX:PDR] subset: human_reference_atlas synonym: "exocrine pancreas glandular cell" RELATED [CALOHA:TS-1242] synonym: "pancreas exocrine glandular cells" RELATED [CALOHA:TS-1242] xref: BTO:0000028 xref: CALOHA:TS-1242 is_a: CL:0000150 ! glandular secretory epithelial cell is_a: CL:0000152 ! exocrine cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000150 ! glandular secretory epithelial cell intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0013697 ! exocrine pancreas epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001602 name: cerebral cortex endothelial cell def: "A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex." [NPX:PDR] subset: cellxgene_subset synonym: "cerebral cortex endothelial cells" RELATED [CALOHA:TS-2372] synonym: "endothelial cells of cerebral cortex" RELATED [CALOHA:TS-2372] xref: CALOHA:TS-2372 is_a: CL:0000115 ! endothelial cell is_a: CL:0002319 ! neural cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000956 ! cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex relationship: part_of UBERON:0013694 ! brain endothelium property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1001602" xsd:string {name="cerebral cortex endothelial cell on CELLxGENE CellGuide"} [Term] id: CL:1001609 name: muscle fibroblast def: "Fibroblast from muscle organ." [NPX:PDR] subset: cellxgene_subset xref: CALOHA:TS-0643 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001630 ! muscle organ relationship: part_of UBERON:0001630 ! muscle organ property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1001609" xsd:string {name="muscle fibroblast on CELLxGENE CellGuide"} [Term] id: CL:1001610 name: bone marrow hematopoietic cell def: "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes." [NPX:PDR] synonym: "bone marrow hematopoietic cells" RELATED [CALOHA:TS-2109] synonym: "bone marrow poietic cells" RELATED [CALOHA:TS-2109] xref: CALOHA:TS-2109 is_a: CL:0000988 ! hematopoietic cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: part_of UBERON:0012429 ! hematopoietic tissue property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_1001610" xsd:string {name="bone marrow hematopoietic cell on CELLxGENE CellGuide"} [Term] id: CL:1100001 name: secretory epithelial cell def: "An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules." [https://orcid.org/0000-0002-7073-9172] is_a: CL:0000066 ! epithelial cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000066 ! epithelial cell intersection_of: CL:0000151 ! secretory cell relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 property_value: dcterms-date "2024-07-21T09:24:44Z" xsd:dateTime [Term] id: CL:2000001 name: peripheral blood mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear leukocyte intersection_of: CL:0000842 ! mononuclear leukocyte intersection_of: part_of UBERON:0000178 ! blood relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000178 ! blood creation_date: 2014-02-11T17:29:04Z [Term] id: CL:2000002 name: decidual cell def: "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization." [BTO:0002770, NCIT:C32429, PMID:30013421, PMID:30429548, Wiki:Decidual_cells&oldid=937509751, Wiki:Decidualization&oldid=908981933] subset: cellxgene_subset synonym: "decidua cell" EXACT [BTO:0002770, NCIT:C32429] synonym: "decidual stromal cell" EXACT [BTO:0005756, PMID:11719592] synonym: "decidualized endometrial stromal cell" EXACT [PMID:31907034] xref: BTO:0002770 xref: BTO:0005756 xref: NCIT:C32429 is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000499 ! stromal cell relationship: develops_from CL:0002255 ! stromal cell of endometrium relationship: part_of UBERON:0002450 ! decidua property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_2000002" xsd:string {name="decidual cell on CELLxGENE CellGuide"} creation_date: 2014-02-20T23:06:41Z [Term] id: CL:2000005 name: brain macroglial cell def: "Any macroglial cell that is part of a brain." [GOC:TermGenie] is_a: CL:0000126 ! macroglial cell intersection_of: CL:0000126 ! macroglial cell intersection_of: part_of UBERON:0000955 ! brain relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000955 ! brain creation_date: 2014-03-28T21:35:27Z [Term] id: CL:2000008 name: microvascular endothelial cell def: "Any blood vessel endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0008339 ! microvascular endothelium relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0008339 ! microvascular endothelium creation_date: 2014-06-04T15:07:42Z [Term] id: CL:2000010 name: dermis blood vessel endothelial cell def: "Any blood vessel endothelial cell that is part of a dermis." [GOC:TermGenie] is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0002067 ! dermis relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002067 ! dermis creation_date: 2014-06-04T15:12:06Z [Term] id: CL:2000012 name: fibroblast of pedal digit skin def: "Any skin fibroblast that is part of a pedal digit skin." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0003530 ! pedal digit skin relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0003530 ! pedal digit skin creation_date: 2014-06-04T15:16:44Z [Term] id: CL:2000013 name: fibroblast of skin of abdomen def: "Any skin fibroblast that is part of a skin of abdomen." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0001416 ! skin of abdomen relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001416 ! skin of abdomen creation_date: 2014-06-04T15:18:16Z [Term] id: CL:2000014 name: fibroblast of upper leg skin def: "Any skin fibroblast that is part of a upper leg skin." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0004262 ! upper leg skin relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0004262 ! upper leg skin creation_date: 2014-06-04T15:19:44Z [Term] id: CL:2000015 name: fibroblast of arm def: "Any skin fibroblast that is part of a arm." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0001460 ! arm relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001460 ! arm creation_date: 2014-06-04T15:29:06Z [Term] id: CL:2000016 name: lung microvascular endothelial cell def: "Any lung endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:1001567 ! lung endothelial cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:1001567 ! lung endothelial cell intersection_of: part_of UBERON:0008339 ! microvascular endothelium relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-04T16:00:56Z [Term] id: CL:2000017 name: fibroblast of peridontal ligament def: "Any fibroblast that is part of a periodontal ligament." [GOC:TermGenie] is_a: CL:0002556 ! fibroblast of periodontium intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0008266 ! periodontal ligament relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0008266 ! periodontal ligament creation_date: 2014-06-04T16:50:33Z [Term] id: CL:2000019 name: compound eye photoreceptor cell def: "Any photoreceptor cell that is part of a compound eye." [GOC:TermGenie] xref: FBbt:00006009 {sssom:mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: CL:0000287 ! eye photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000018 ! compound eye relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000018 ! compound eye creation_date: 2014-06-24T23:16:45Z [Term] id: CL:2000020 name: inner cell mass cell def: "Any native cell that is part of a inner cell mass." [GOC:TermGenie] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000087 ! inner cell mass relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000087 ! inner cell mass creation_date: 2014-06-24T23:16:53Z [Term] id: CL:2000022 name: cardiac septum cell def: "Any native cell that is part of a cardiac septum." [GOC:TermGenie] is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0002099 ! cardiac septum relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002099 ! cardiac septum creation_date: 2014-06-24T23:17:07Z [Term] id: CL:2000025 name: spinal cord oligodendrocyte def: "Any oligodendrocyte that is part of a spinal cord." [GOC:TermGenie] is_a: CL:0000128 ! oligodendrocyte intersection_of: CL:0000128 ! oligodendrocyte intersection_of: part_of UBERON:0002240 ! spinal cord relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002240 ! spinal cord creation_date: 2014-06-25T00:23:50Z [Term] id: CL:2000029 name: central nervous system neuron def: "Any neuron that is part of a central nervous system." [GOC:TermGenie] subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0001017 ! has soma location central nervous system relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: RO:0002100 UBERON:0001017 ! has soma location central nervous system property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-06-25T01:17:43Z [Term] id: CL:2000032 name: peripheral nervous system neuron def: "A neuron that is part of a peripheral nervous system." [GOC:TermGenie, ISBN:0721662544] subset: cellxgene_subset subset: human_reference_atlas synonym: "peripheral neuron" EXACT [] synonym: "PNS neuron" EXACT [] xref: FMA:84664 is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0000010 ! has soma location peripheral nervous system relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: RO:0002100 UBERON:0000010 ! has soma location peripheral nervous system property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-06-25T02:28:17Z [Term] id: CL:2000040 name: bladder microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a urinary bladder." [GOC:TermGenie] subset: human_reference_atlas is_a: CL:1001319 ! bladder cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-07-09T00:04:47Z [Term] id: CL:2000042 name: embryonic fibroblast def: "Any fibroblast that is part of a embryo." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000922 ! embryo relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000922 ! embryo creation_date: 2014-07-09T00:12:00Z [Term] id: CL:2000044 name: brain microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a brain." [GOC:TermGenie] is_a: CL:0002319 ! neural cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0000955 ! brain relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000955 ! brain creation_date: 2014-07-09T00:24:53Z [Term] id: CL:2000046 name: ventricular cardiac muscle cell def: "Any cardiac muscle cell that is part of a cardiac ventricle." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000746 ! cardiac muscle cell intersection_of: CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_2000046" xsd:string {name="ventricular cardiac muscle cell on CELLxGENE CellGuide"} creation_date: 2014-08-12T20:50:28Z [Term] id: CL:2000047 name: brainstem motor neuron def: "Any motor neuron that is part of a brainstem." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0000100 ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: RO:0002100 UBERON:0002298 ! has soma location brainstem relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: RO:0002100 UBERON:0002298 ! has soma location brainstem creation_date: 2014-10-02T23:52:53Z [Term] id: CL:2000051 name: splenic fibroblast def: "Any fibroblast that is part of a spleen." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002106 ! spleen relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002106 ! spleen creation_date: 2014-10-06T18:58:47Z [Term] id: CL:2000052 name: umbilical artery endothelial cell def: "Any endothelial cell of artery that is part of a umbilical cord." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=8010 is_a: CL:0000349 ! extraembryonic cell is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:1000413 ! endothelial cell of artery intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002331 ! umbilical cord creation_date: 2014-10-06T19:01:48Z [Term] id: CL:2000053 name: splenic endothelial cell def: "Any endothelial cell that is part of a spleen." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5500 subset: human_reference_atlas is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0002106 ! spleen relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002106 ! spleen property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-06T19:06:04Z [Term] id: CL:2000055 name: liver dendritic cell def: "Any dendritic cell that is part of a liver." [GOC:TermGenie] comment: http://www.jleukbio.org/content/66/2/322.abstract subset: cellxgene_subset synonym: "hepatic dendritic cell" EXACT [] is_a: CL:0000451 ! dendritic cell intersection_of: CL:0000451 ! dendritic cell intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002107 ! liver property_value: seeAlso "https://cellxgene.cziscience.com/cellguide/CL_2000055" xsd:string {name="liver dendritic cell on CELLxGENE CellGuide"} creation_date: 2014-10-06T19:16:11Z [Term] id: CL:2000061 name: placental amniotic mesenchymal stromal cell def: "Any mesenchymal stem cell that is part of a placenta." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7140 subset: human_reference_atlas is_a: CL:0000134 ! mesenchymal stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001987 ! placenta property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-07T17:51:11Z [Term] id: CL:2000062 name: placental villus capillary endothelial cell def: "Any capillary endothelial cell that is part of a placenta." [GOC:TermGenie] comment: http://www.ncbi.nlm.nih.gov/books/NBK53245/ subset: human_reference_atlas is_a: CL:0002144 ! capillary endothelial cell is_a: CL:0009092 ! endothelial cell of placenta intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-07T17:55:56Z [Term] id: CL:2000063 name: ovarian fibroblast def: "Any fibroblast that is part of a female gonad." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7330 is_a: CL:0000057 ! fibroblast is_a: CL:0002132 ! stromal cell of ovary intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000992 ! ovary relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T17:57:42Z [Term] id: CL:2000065 name: ovarian microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a female urethra." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7300 is_a: CL:1001320 ! urethra cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001334 ! female urethra relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001334 ! female urethra creation_date: 2014-10-07T18:18:01Z [Term] id: CL:2000066 name: cardiac ventricle fibroblast def: "Any fibroblast that is part of a cardiac ventricle." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6310 subset: human_reference_atlas is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-07T18:35:38Z [Term] id: CL:2000067 name: cardiac atrium fibroblast def: "Any fibroblast that is part of a cardiac atrium." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6320 subset: human_reference_atlas is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002081 ! cardiac atrium property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-07T18:36:54Z [Term] id: CL:2000068 name: pericardium fibroblast def: "Any fibroblast that is part of a pericardium." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6430 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002407 ! pericardium relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002407 ! pericardium creation_date: 2014-10-07T18:38:06Z [Term] id: CL:2000069 name: gallbladder fibroblast def: "Any fibroblast that is part of a gallbladder." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5430 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002110 ! gallbladder relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002110 ! gallbladder creation_date: 2014-10-07T18:41:43Z [Term] id: CL:2000070 name: optic choroid fibroblast def: "Any fibroblast that is part of a optic choroid." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6620 is_a: CL:0000005 ! neural crest derived fibroblast is_a: CL:0000348 ! choroidal cell of the eye intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001776 ! optic choroid relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 creation_date: 2014-10-07T18:50:43Z [Term] id: CL:2000072 name: adipose microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a adipose tissue." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7200 is_a: CL:0002320 ! connective tissue cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001013 ! adipose tissue relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001013 ! adipose tissue creation_date: 2014-10-07T22:13:45Z [Term] id: CL:2000073 name: migratory cardiac neural crest cell def: "Any migratory neural crest cell that is part of a cardiac neural crest." [GOC:TermGenie] synonym: "cardiac neural crest cell" EXACT [PMID:33060096] is_a: CL:0000333 ! migratory neural crest cell intersection_of: CL:0000333 ! migratory neural crest cell intersection_of: part_of UBERON:0000095 ! cardiac neural crest relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000095 ! cardiac neural crest creation_date: 2014-11-05T01:18:43Z [Term] id: CL:2000074 name: splenocyte def: "Any leukocyte that is part of a spleen." [GOC:TermGenie] comment: Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology. is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: part_of UBERON:0002106 ! spleen relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002106 ! spleen creation_date: 2014-11-05T01:26:50Z [Term] id: CL:2000076 name: hindlimb stylopod vein endothelial cell def: "Any vein endothelial cell that is part of a hindlimb stylopod." [GOC:TermGenie] is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0002543 ! vein endothelial cell intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000376 ! hindlimb stylopod creation_date: 2014-12-02T18:40:47Z [Term] id: CL:2000079 name: mesenchymal stem cell of femoral bone marrow def: "Any mesenchymal stem cell of the bone marrow that is part of a femur." [GOC:TermGenie] is_a: CL:0002540 ! mesenchymal stem cell of the bone marrow intersection_of: CL:0002540 ! mesenchymal stem cell of the bone marrow intersection_of: part_of UBERON:0000981 ! femur relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000981 ! femur creation_date: 2014-12-02T19:07:31Z [Term] id: CL:2000080 name: mesenchymal stem cell of abdominal adipose tissue def: "Any mesenchymal stem cell of adipose tissue that is part of an abdomen." [GOC:TermGenie] synonym: "mesenchymal stem cell of abdominal adipose" EXACT [] is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: part_of UBERON:0000916 ! abdomen relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000916 ! abdomen creation_date: 2014-12-02T19:10:34Z [Term] id: CL:2000085 name: mononuclear cell of umbilical cord def: "Any mononuclear cell that is part of a umbilical cord." [GOC:TermGenie] is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000842 ! mononuclear leukocyte intersection_of: CL:0000842 ! mononuclear leukocyte intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002331 ! umbilical cord creation_date: 2014-12-02T20:14:16Z [Term] id: CL:2000091 name: endometrial microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a endometrial blood vessel." [GOC:TermGenie] subset: human_reference_atlas is_a: CL:0009095 ! endothelial cell of uterus is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0015172 ! endometrial blood vessel relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0015172 ! endometrial blood vessel property_value: RO:0002175 NCBITaxon:9606 creation_date: 2015-03-31T21:02:36Z [Term] id: CL:2000093 name: bronchus fibroblast of lung def: "Any fibroblast of lung that is part of a bronchus." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0002553 ! fibroblast of lung intersection_of: CL:0002553 ! fibroblast of lung intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002185 ! bronchus creation_date: 2015-03-31T21:16:22Z [Term] id: CL:2000095 name: cord blood hematopoietic stem cell def: "Any hematopoietic stem cell that is part of a umbilical cord blood." [GOC:TermGenie] subset: cellxgene_subset is_a: CL:0002246 ! peripheral blood stem cell is_a: CL:0002352 ! gestational hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0012168 ! umbilical cord blood relationship: dc-contributor http://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0012168 ! umbilical cord blood creation_date: 2015-05-26T18:58:34Z [Term] id: CL:3000004 name: peripheral sensory neuron def: "A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing." [GOC:CellBLAST, https://www.britannica.com/science/sensory-neuron, https://www.ncbi.nlm.nih.gov/books/NBK539846/, PMID:30096314, PMID:31554486, PMID:35858549, Wikipedia:Sensory_neuron] comment: Typically, a sensory neuron has a pseudounipolar morphology. {xref="Wikipedia:Sensory_neuron"} is_a: CL:0000101 ! sensory neuron is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:2000032 ! peripheral nervous system neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: dc-contributor http://www.wikidata.org/entity/Q97529981 creation_date: 2019-02-25T19:34:33Z [Term] id: CL:4023059 name: committed oligodendrocyte precursor def: "An oligodendrocyte precursor cell that is committed to differentiate." [PMID:32066987] comment: COPs are distinct from OPCs in that the lack expression of Pdgfra and Cspg4 and come out as distinct clusters in transcriptomic profiling. This is the reason that this term is not modelled as a subclassOf OPC but instead linked using develops_from. {xref="PMID:27284195"} subset: cellxgene_subset subset: human_reference_atlas synonym: "COP" EXACT OMO:0003000 [] synonym: "differentiation-committed oligodendrocyte precursor" EXACT [] is_a: CL:0000123 ! neuron associated cell (sensu Vertebrata) relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 relationship: develops_from CL:0002453 ! oligodendrocyte precursor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4023072 name: brain vascular cell def: "A cell that is part of the brain vasculature." [DOI:10.1101/2022.10.12.511898] subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0002319 ! neural cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0008998 ! vasculature of brain relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 relationship: part_of UBERON:0008998 ! vasculature of brain property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4023079 name: midbrain-derived inhibitory neuron def: "A GABAergic inhibitory neuron that is derived from the midbrain." [DOI:10.1101/2022.10.12.511898] subset: human_reference_atlas is_a: CL:2000029 ! central nervous system neuron is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000540 ! neuron intersection_of: develops_from UBERON:0001891 ! midbrain relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 relationship: develops_from UBERON:0001891 ! midbrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4023154 name: myelinating glial cell def: "A glial cell that myelinates axonal processes." [DOI:10.1007/3-540-29623-9_3240] is_a: CL:0000125 ! glial cell intersection_of: CL:0000125 ! glial cell intersection_of: has_part GO:0043209 ! myelin sheath relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 relationship: has_part GO:0043209 ! myelin sheath [Term] id: CL:4023168 name: somatosensory neuron def: "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli." [PMID:22865660] is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: part_of UBERON:0003942 ! somatosensory system intersection_of: RO:0002100 UBERON:0000010 ! has soma location peripheral nervous system relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 relationship: part_of UBERON:0003942 ! somatosensory system [Term] id: CL:4028001 name: pulmonary capillary endothelial cell def: "Any capillary endothelial cell that is part of a lung." [] subset: cellxgene_subset synonym: "lung capillary endothelial cell" EXACT [] is_a: CL:0002144 ! capillary endothelial cell is_a: CL:2000016 ! lung microvascular endothelial cell intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0002048 ! lung relationship: dc-contributor https://orcid.org/0000-0002-3293-5463 relationship: part_of UBERON:0016405 ! pulmonary capillary creation_date: 2021-11-23T02:31:40Z [Term] id: CL:4030022 name: renal medullary fibroblast def: "A fibroblast that is located in the renal medulla interstitium." [https://doi.org/10.1101/2021.07.28.454201, PMID:10559635] comment: It has been noted that inner medullary fibroblasts are involved in the regulation of water and electrolyte homeostasis. {xref="PMID:10559635"} subset: cellxgene_subset subset: human_reference_atlas synonym: "kidney medullary fibroblast" EXACT [] is_a: CL:1000682 ! kidney medulla interstitial cell is_a: CL:1000692 ! kidney interstitial fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005211 ! renal medulla interstitium property_value: dcterms-date "2022-07-05T12:13:40Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4030025 name: renal cortical fibroblast def: "A fibroblast that is located in the renal cortical interstitium." [PMID:10559635] comment: Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin. {xref="PMID:16230044"} synonym: "kidney cortical fibroblast" EXACT [] is_a: CL:1000681 ! kidney cortex interstitial cell is_a: CL:1000692 ! kidney interstitial fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005270 ! renal cortex interstitium property_value: dcterms-date "2022-07-05T15:50:17Z" xsd:dateTime [Term] id: CL:4030029 name: blood lymphocyte def: "A lymphocyte located in blood." [https://orcid.org/0000-0001-9990-8331] subset: blood_and_immune_upper_slim is_a: CL:0000542 ! lymphocyte is_a: CL:2000001 ! peripheral blood mononuclear cell intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0000178 ! blood property_value: dcterms-date "2022-11-04T14:40:00Z" xsd:dateTime [Term] id: CL:4030031 name: interstitial cell def: "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes." [PMID:24987007] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0005169 ! interstitial tissue relationship: part_of UBERON:0005169 ! interstitial tissue property_value: dcterms-date "2022-11-30T14:35:08Z" xsd:dateTime [Term] id: CL:4030035 name: dental pulp stem cell def: "A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation." [DOI:10.1177/154405910208100806, https://orcid.org/0000-0002-2825-0621] synonym: "DPSC" EXACT OMO:0003000 [] is_a: CL:0000034 ! stem cell is_a: CL:0002148 ! dental pulp cell intersection_of: CL:0000034 ! stem cell intersection_of: part_of UBERON:0001754 ! dental pulp property_value: dcterms-date "2023-01-10T14:02:02Z" xsd:dateTime [Term] id: CL:4030066 name: ureteric bud cell def: "An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion." [PMID:17133361, PMID:24183650, PMID:9374839] subset: cellxgene_subset synonym: "UB cell" RELATED OMO:0003000 [PMID:24183650] is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000084 ! ureteric bud relationship: part_of UBERON:0000084 ! ureteric bud relationship: participates_in GO:2001013 {xref="PMID:9374839"} ! epithelial cell proliferation involved in renal tubule morphogenesis property_value: dc-contributor "https://orcid.org/0000-0002-1425-877X" xsd:string property_value: dcterms-date "2023-10-13T11:22:42Z" xsd:dateTime [Term] id: CL:4033002 name: neuroendocrine cell of epithelium of crypt of Lieberkuhn def: "A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn." [PMID:31390635] is_a: CL:0000150 ! glandular secretory epithelial cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0011184 ! epithelium of crypt of Lieberkuhn relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of UBERON:0011184 ! epithelium of crypt of Lieberkuhn [Term] id: CL:4033005 name: serous secreting cell of bronchus submucosal gland def: "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland." [PMID:5487122, PMID:9651178] comment: The marker set PRR4, C6orf58 can identify the Human cell type serous secreting cell of bronchus submucosal gland in the lung with a confidence of 0.75 (NS-Forest FBeta value). {xref="https://doi.org/10.5281/zenodo.11165918"} subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000152 ! exocrine cell is_a: CL:0019001 ! tracheobronchial serous cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:8410043 ! bronchus submucosal gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:8410043 ! bronchus submucosal gland relationship: RO:0015004 CLM:1000054 ! has characterizing marker set property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033008 name: vein endothelial cell of respiratory system def: "A(n) vein endothelial cell that is part of a(n) respiratory system." [PMID:34030460] subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0002543 ! vein endothelial cell intersection_of: part_of UBERON:0001004 ! respiratory system relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0001004 ! respiratory system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033018 name: lung megakaryocyte def: "A megakaryocyte that is resident in the lung connective tissue." [PMID:33351116] subset: cellxgene_subset subset: human_reference_atlas synonym: "lung MKs" RELATED OMO:0003004 [PMID:33351116] synonym: "lung resident megakaryocyte" EXACT [PMID:36524131] synonym: "lung-resident megakaryocyte" EXACT [PMID:36524131] synonym: "MKL" RELATED OMO:0003000 [PMID:36524131] is_a: CL:0000556 ! megakaryocyte is_a: CL:0002320 ! connective tissue cell intersection_of: CL:0000556 ! megakaryocyte intersection_of: part_of UBERON:0000114 ! lung connective tissue relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 relationship: part_of UBERON:0000114 ! lung connective tissue property_value: dcterms-date "2023-03-16T11:31:23Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033020 name: mucus secreting cell of trachea gland def: "A mucus secreting cell that is part of a submucosal gland of the trachea." [PMID:18931053, PMID:29656943] subset: human_reference_atlas synonym: "tracheal submucosal gland mucous cell" EXACT [PMID:18931053] is_a: CL:0000307 ! tracheal epithelial cell is_a: CL:4033037 ! mucus secreting cell of tracheobronchial tree submucosal gland intersection_of: CL:0000319 ! mucus secreting cell intersection_of: part_of UBERON:0005203 ! trachea gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 relationship: part_of UBERON:0005203 ! trachea gland property_value: dcterms-date "2023-03-16T13:03:13Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033022 name: mucus secreting cell of bronchus submucosal gland def: "A mucus secreting cell of a submucosal gland of the bronchus." [PMID:19965983] comment: The marker set BPIFB2 can identify the Human cell type mucus secreting cell of bronchus submucosal gland in the lung with a confidence of 0.93 (NS-Forest FBeta value). {xref="https://doi.org/10.5281/zenodo.11165918"} subset: cellxgene_subset subset: human_reference_atlas synonym: "bronchial gland mucous cell" EXACT [PMID:5487122] is_a: CL:0002328 ! bronchial epithelial cell is_a: CL:4033037 ! mucus secreting cell of tracheobronchial tree submucosal gland intersection_of: CL:0000319 ! mucus secreting cell intersection_of: part_of UBERON:8410043 ! bronchus submucosal gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 relationship: part_of UBERON:8410043 ! bronchus submucosal gland relationship: RO:0015004 CLM:1000053 ! has characterizing marker set property_value: dcterms-date "2023-03-16T15:12:52Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033037 name: mucus secreting cell of tracheobronchial tree submucosal gland def: "A mucus secreting cell of a submucosal gland of the tracheobronchial tree." [PMID:30864819] subset: cellxgene_subset is_a: CL:0000150 ! glandular secretory epithelial cell is_a: CL:0000152 ! exocrine cell is_a: CL:0000319 ! mucus secreting cell is_a: CL:0002202 ! epithelial cell of tracheobronchial tree is_a: CL:0008055 ! respiratory tract secretory epithelial cell intersection_of: CL:0000319 ! mucus secreting cell intersection_of: part_of UBERON:0007196 ! tracheobronchial tree intersection_of: part_of UBERON:8410077 ! airway submucosal gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:8410077 ! airway submucosal gland property_value: dcterms-date "2023-04-20T10:55:50Z" xsd:dateTime [Term] id: CL:4033049 name: taste receptor cell of tongue def: "A taste receptor cell that is part of a taste bud of a tongue." [DOI:10.1111/j.1096-3642.1981.tb01137.x, http://www.nejohnston.org/Birds/documents/AvianTongues_Johnston.pdf, PMID:10052456, PMID:28655883] synonym: "gustatory cell of tongue" RELATED [DOI:10.1016/s0022-5320(69)80043-2] is_a: CL:0000209 ! taste receptor cell is_a: CL:0002319 ! neural cell intersection_of: CL:0000209 ! taste receptor cell intersection_of: part_of UBERON:0014451 ! tongue taste bud relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0014451 ! tongue taste bud property_value: dcterms-date "2023-05-03T07:59:58Z" xsd:dateTime [Term] id: CL:4033050 name: catecholaminergic neuron def: "A neuron that releases catecholamine as a neurotransmitter." [ISBN:0521442516, PMID:12094209] comment: Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis. {xref="https://orcid.org/0000-0002-2244-7917", xref="PMID:12128258", xref="PMID:10191060", xref="PMID:34880760"} subset: human_reference_atlas is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0160043 ! catecholamine secretion, neurotransmission relationship: capable_of GO:0160043 ! catecholamine secretion, neurotransmission relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 property_value: dcterms-date "2023-05-18T12:07:45Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033054 name: perivascular cell def: "A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics." [PMID:24928499, PMID:27889329] subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: adjacent_to UBERON:0002049 ! vasculature relationship: adjacent_to UBERON:0002049 ! vasculature relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 property_value: dcterms-date "2023-08-22T13:40:28Z" xsd:dateTime [Term] id: CL:4033061 name: endothelial cell of central vein of liver def: "An endothelial cell that is part of a central vein of liver." [PMID:28287163] synonym: "endothelial cell of central vein" BROAD [PMID:28287163] is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0006841 ! central vein of liver relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0006841 ! central vein of liver [Term] id: CL:4033093 name: limbal epithelial stem cell of cornea def: "A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023)." [PMID:20614614, PMID:29105366, PMID:36983561, PMID:37768272] synonym: "LESC" RELATED OMO:0003000 [PMID:20614614] synonym: "limbal epithelial stem cell" EXACT [PMID:20614614] synonym: "limbal stem cell" EXACT [PMID:17562792] synonym: "LSC" RELATED OMO:0003000 [PMID:36983561] is_a: CL:0000036 ! epithelial fate stem cell intersection_of: CL:0000034 ! stem cell intersection_of: part_of UBERON:0006761 ! corneo-scleral junction relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0001-7655-4833 relationship: develops_into CL:0000575 ! corneal epithelial cell relationship: part_of UBERON:0000482 ! basal lamina of epithelium relationship: part_of UBERON:0006761 ! corneo-scleral junction property_value: dcterms-date "2024-12-11T13:59:19Z" xsd:dateTime [Term] id: CL:4040004 name: mesenchymal stem cell of orbital adipose tissue def: "Any mesenchymal stem cell of adipose tissue that is part of an orbital region." [https://orcid.org/0000-0002-0819-0473] synonym: "OAMSC" EXACT [PMID:31377878] synonym: "orbital adipose-derived mesenchymal stem cell" EXACT [PMID:31377878] synonym: "Orbital ASCs" EXACT [PMID:30210548] is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: part_of UBERON:0004088 ! orbital region relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0004088 ! orbital region property_value: dcterms-date "2023-09-18T10:43:00Z" xsd:dateTime [Term] id: CL:4047023 name: intestinal lamina propria fibroblast def: "A fibroblast located in the lamina propria of the intestinal mucosa. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is predominantly located in the small intestine adjacent to myofibroblasts surrounding the crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin." [PMID:21252048, PMID:36032088] synonym: "S1 fibroblast" RELATED [PMID:30270042] is_a: CL:0000057 ! fibroblast is_a: CL:0000151 ! secretory cell intersection_of: CL:0000057 ! fibroblast intersection_of: capable_of GO:0070278 ! extracellular matrix constituent secretion intersection_of: part_of UBERON:0004780 ! gastrointestinal system lamina propria relationship: capable_of GO:0070278 ! extracellular matrix constituent secretion relationship: dc-contributor https://orcid.org/0009-0005-7919-4905 relationship: part_of UBERON:0004780 ! gastrointestinal system lamina propria property_value: dcterms-date "2024-09-24T15:45:18Z" xsd:dateTime [Term] id: CL:4047025 name: type G cell of stomach def: "Any type G enteroendocrine cell that is part of some epithelium of stomach." [FBC:Autogenerated] is_a: CL:0000508 ! type G enteroendocrine cell is_a: CL:1000222 ! stomach neuroendocrine cell intersection_of: CL:0000508 ! type G enteroendocrine cell intersection_of: part_of UBERON:0001276 ! epithelium of stomach relationship: dc-contributor https://orcid.org/0009-0005-7919-4905 property_value: dcterms-date "2024-10-24T10:43:22Z" xsd:dateTime [Term] id: CL:4047034 name: smooth muscle cell of stomach def: "A smooth muscle cell that is part of the muscularis externa of the stomach wall. It is characterized by its fusiform shape, involuntary control, and ability to generate slow, sustained contractions. This cell is organized in distinct layers and is essential for gastric motility and digestion." [PMID:21443757, PMID:33630273] is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0008856 ! stomach muscularis externa relationship: dc-contributor https://orcid.org/0009-0005-7919-4905 relationship: part_of UBERON:0008856 ! stomach muscularis externa property_value: dcterms-date "2024-12-05T11:10:18Z" xsd:dateTime [Term] id: CL:4052002 name: syncytial cell def: "A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm." [PMID:20851884, Wikipedia:Syncytium] synonym: "SC" RELATED OMO:0003000 [PMID:9067520] synonym: "syncytium" EXACT [WBbt:0008074] is_a: CL:0000228 ! multinucleate cell intersection_of: CL:0000000 ! cell intersection_of: output_of GO:0000768 ! syncytium formation by plasma membrane fusion intersection_of: RO:0000053 PATO:0001908 ! bearer of multinucleate relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: output_of GO:0000768 ! syncytium formation by plasma membrane fusion property_value: dcterms-date "2024-08-15T10:38:46Z" xsd:dateTime [Term] id: CL:4052003 name: intestinal villus capillary endothelial cell def: "A capillary endothelial cell that is part of the intestinal villus. This cell is highly fenestrated, with fenestrations most numerous at the villus tips, and plays a vital role in nutrient absorption and maintaining the selective permeability of the intestinal barrier." [PMID:18480313, PMID:35810168, PMID:38051275] synonym: "villus blood capillary endothelial cells" BROAD [PMID:35810168] synonym: "villus tip endothelial cell" RELATED [PMID:38051275] is_a: CL:0000131 ! gut endothelial cell is_a: CL:0000666 ! fenestrated endothelial cell is_a: CL:0002144 ! capillary endothelial cell intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0001213 ! intestinal villus relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: part_of UBERON:0001213 ! intestinal villus property_value: dcterms-date "2024-09-17T10:03:25Z" xsd:dateTime [Term] id: CL:4052006 name: intestinal enteroendocrine progenitor def: "An epithelial cell that is part of the crypt of Lieberkuhn, originating from intestinal stem cells and giving rise to enteroendocrine cells (EECs). In mouse and human, this cell can be characterized by the expression of Neurog3, and has the ability to proliferate and differentiate into multiple EEC subtypes. Its proliferative potential contributes to crypt growth, distinguishing it from fully differentiated EECs." [doi:/10.1038/s41467-021-27901-5, PMID:31756561, PMID:32531023, PMID:35913117, PMID:38260422] comment: The EEC progenitor is also present in other organisms; for example, flies have EEC progenitors but lack intestinal crypts and do not express the same markers. Instead, they are Dl+ and Pros+. {xref="PMID:25670791"} synonym: "EEC Progenitor" RELATED OMO:0003000 [PMID:31756561] is_a: CL:0002563 ! intestinal epithelial cell is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: develops_from CL:0002250 ! intestinal crypt stem cell relationship: part_of UBERON:0011184 ! epithelium of crypt of Lieberkuhn property_value: dcterms-date "2024-09-20T12:13:26Z" xsd:dateTime [Term] id: CL:4052014 name: pancreatic islet capillary endothelial cell def: "A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture." [PMID:16607697, PMID:27124642, PMID:28396983, PMID:33200981] synonym: "islet endothelial cell" BROAD [PMID:16607697, PMID:28396983] synonym: "pancreatic islet endothelial cell" BROAD [PMID:16607697] is_a: CL:0000666 ! fenestrated endothelial cell is_a: CL:0002144 ! capillary endothelial cell intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0000006 ! islet of Langerhans relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: dcterms-date "2024-09-30T14:36:12Z" xsd:dateTime [Term] id: CL:4052015 name: endocrine gland capillary endothelial cell def: "Any capillary endothelial cell that is part of an endocrine gland." [PMID:18480313] is_a: CL:0002144 ! capillary endothelial cell intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0002368 ! endocrine gland relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: part_of UBERON:0002368 ! endocrine gland property_value: dcterms-date "2024-09-30T15:27:49Z" xsd:dateTime [Term] id: CL:4052018 name: fallopian tube epithelial cell def: "Any epithelial cell that is part of the fallopian tube." [Wikipedia:Fallopian_tube] synonym: "oviduct epithelial cell" BROAD [Wikipedia:Fallopian_tube] synonym: "uterine tube epithelial cell" EXACT [Wikipedia:Fallopian_tube] is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: part_of UBERON:0003889 ! fallopian tube property_value: dcterms-date "2024-10-01T12:09:12Z" xsd:dateTime [Term] id: CL:4052022 name: fallopian tube smooth muscle cell def: "A smooth muscle cell that is part of the fallopian tube. This cell is responsible for peristaltic contractions that facilitate gamete and embryo transport, fluid mixing, and embryo admission to the uterus." [PMID:31183831, PMID:31613440] comment: The fallopian tube smooth muscle cell in the human contracts dynamically in response to hormones and signaling molecules. Prostaglandins, particularly PGF2α and PGE2, have been shown to increase muscular contractions, while progesterone, levonorgestrel, mifepristone, oxytocin, and human chorionic gonadotropin (hCG) decrease them. These contractile responses are crucial for regulating gamete and embryo transport through the fallopian tube. {xref="PMID:18621753"} synonym: "oviduct smooth muscle cell" BROAD [PMID:31613440] synonym: "uterine tube smooth muscle cell" EXACT [PMID:31613440] is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: part_of UBERON:0003889 ! fallopian tube property_value: dcterms-date "2024-10-21T12:16:54Z" xsd:dateTime [Term] id: CL:4052030 name: adventitial fibroblast def: "A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression" [PMID:28705796, PMID:36718802] comment: Single-cell transcriptomics of murine aorta identifies two adventitial fibroblast-specific markers, PDGFRA and DPEP1, which were validated at the protein level by immunohistochemistry and flow cytometry across human and murine arteries, highlighting fibroblast heterogeneity in health and cardiovascular disease (CVD) in humans and mice. {xref="PMID:36718802"} is_a: CL:0000057 ! fibroblast is_a: CL:0000151 ! secretory cell is_a: CL:0002503 ! adventitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005734 ! tunica adventitia of blood vessel relationship: capable_of GO:0001816 ! cytokine production relationship: capable_of GO:0070278 ! extracellular matrix constituent secretion relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: part_of UBERON:0005734 ! tunica adventitia of blood vessel property_value: dcterms-date "2024-12-05T11:01:15Z" xsd:dateTime [Term] id: CL:4052045 name: steroidogenic stromal cell of ovary def: "A stromal cell that is part of the ovarian stroma, characterized by its ability to synthesize steroid hormones." [doi:/10.1101/2024.12.15.628550, PMID:36205477] synonym: "Enpp2− interstitial cell" RELATED [PMID:36205477] synonym: "steroidogenic interstitial stromal cell" BROAD [PMID:36205477] synonym: "steroidogenic stromal cell" BROAD [PMID:36205477] is_a: CL:0002132 ! stromal cell of ovary intersection_of: CL:0000499 ! stromal cell intersection_of: capable_of GO:0120178 ! steroid hormone biosynthetic process intersection_of: part_of UBERON:0006960 ! ovary stroma relationship: capable_of GO:0120178 ! steroid hormone biosynthetic process relationship: dc-contributor https://orcid.org/0009-0000-8480-9277 relationship: part_of UBERON:0006960 ! ovary stroma property_value: dcterms-date "2025-03-05T13:37:44Z" xsd:dateTime [Term] id: COB:0000011 name: atom def: "A material entity consisting of exactly one atomic nucleus and the electron(s) orbiting it." [] is_a: BFO:0000040 ! material entity disjoint_from: COB:0000013 ! molecule relationship: has_part CHEBI:33252 ! atomic nucleus property_value: editor_note "This atom is closely related to ChEBI's atom, but not exactly equivalent to." xsd:string [Term] id: COB:0000013 name: molecule def: "A material entity that consists of two or more atoms that are all connected via covalent bonds such that any atom can be transitively connected with any other atom." [] is_a: BFO:0000040 ! material entity relationship: has_part COB:0000011 ! atom property_value: editor_note "This molecular entity is different than ChEBI's 'molecular entity'." xsd:string property_value: editor_note "We would like to have cardinality restrictions on the logic, but there are some technical limitations." xsd:string [Term] id: COB:0000021 name: gross anatomical part def: "A part of a multicellular organism that is a collection of cell components that are not all contained in one cell." [] is_a: UBERON:0000465 ! material anatomical entity [Term] id: COB:0000022 name: organism def: "A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome" [] is_a: UBERON:0000465 ! material anatomical entity property_value: editor_note "'Maximal functionally integrated unit' is intended to express unity, which Barry considers synonymous with BFO 'object'." xsd:string property_value: editor_note "Includes virus - we will later have a class for cellular organisms." xsd:string [Term] id: COB:0000035 name: completely executed planned process is_a: COB:0000082 ! planned process is_a: OBI:0000011 ! planned process disjoint_from: GO:0008150 ! biological process relationship: BFO:0000055 OBI:0000260 ! realizes plan [Term] id: COB:0000080 name: complex of molecules def: "A complex of two or more molecules that are not covalently bound." [] is_a: BFO:0000040 ! material entity relationship: has_part COB:0000013 ! molecule [Term] id: COB:0000082 name: planned process def: "A process that is initiated by an agent who intends to carry out a plan to achieve an objective through one or more actions as described in a plan specification." [] is_a: BFO:0000015 ! process is_a: http://rs.tdwg.org/dwc/terms/Event ! Event [Term] id: COB:0000502 name: characteristic [Term] id: FOVT:0000001 name: body length with tail def: "The length of a body that includes the tail." [https://orcid.org/0000-0003-2699-3066] comment: This is measured from the snout to the end of the tail along the anterior-posterior axis in four-legged vertebrates. synonym: "total length" EXACT [] is_a: OBA:VT0001256 ! body length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000002 name: body length without tail def: "The length of a body that excludes a tail." [https://orcid.org/0000-0003-2699-3066] comment: This is measured from the snout to before the tail, usually ending at the anus in four-legged vertebrates. synonym: "head-body length" EXACT [] synonym: "snout-vent length" RELATED [] is_a: OBA:VT0001256 ! body length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000003 name: pes length with nail def: "A length measurement of a hindfoot that includes the nail." [https://orcid.org/0000-0003-2699-3066] def: "The length of a hindfoot that includes the nail." [https://orcid.org/0000-0003-2699-3066] synonym: "hindfoot length" RELATED [] synonym: "hindfoot length length with nail" EXACT [] is_a: OBA:1000049 ! pes length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0000004 name: pes length without nail def: "The length of a hindfoot that excludes the nail." [https://orcid.org/0000-0003-2699-3066] synonym: "hindfoot length" RELATED [] synonym: "hindfoot length without nail" EXACT [] is_a: OBA:1000049 ! pes length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0000005 name: ear length to notch def: "The length of a line of an ear from the lower notch of the pinna to the tip of the pinna." [] is_a: OBA:0003426 ! external ear length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000006 name: femur length from greater trochanter to lateral condyle def: "The length from a lateral condyle of femur to a greater trochanter of a femur." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "femur lateral length" EXACT [] synonym: "femur maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004348 ! femur length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000007 name: obsolete femur length from caput to medial condyle def: "OBSOLETE The length from a medial condyle of femur to a head of femur." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9780873659505] comment: term doesn't exist, it should be lateral condyle synonym: "femur greatest length from caput femoris (GLC)" EXACT [ISBN:9780873659505] synonym: "femur medial length" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001070 [Term] id: FOVT:0000008 name: humerus length from trochlea to caput def: "The length from a trochlea of a humerus to a proximal head of a humerus (caput)." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus greatest length from caput (GLC)" RELATED [ISBN:9780873659505] synonym: "humerus maximal length from caput (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004350 ! humerus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000009 name: humerus length from trochlea to greater tubercle def: "The length from a trochlea of a humerus to a ventral tubercle (greater tubercle) of a humerus." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "humerus length from trochlea to ventral tubercle" EXACT [] synonym: "humerus maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004350 ! humerus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000010 name: obsolete talus distal articular breadth def: "OBSOLETE Medial-lateral width of the distal end of an astragalus." [] comment: astragalus head breadth comment: Redundant with FOVT:0000017 synonym: "astragalus greatest breadth distal" EXACT [] synonym: "talus distal width ML" EXACT [] synonym: "talus head width" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0000017 [Term] id: FOVT:0000012 name: obsolete width of the trochlea of talus def: "OBSOLETE Length between the proximal-most points of the medial and lateral trochlear ridges of an astragalus." [] comment: This is not a measurement FOVT has a need for. synonym: "breadth of the trochlea" EXACT [] synonym: "breadth of the trochlea of talus" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0000013 name: astragalus lateral length def: "The length of the lateral side of an astragalus (talus) along the proximal-distal axis." [ISBN:9780873659505] synonym: "astragalus greatest length of the lateral half (GLl)" RELATED [ISBN:9780873659505] synonym: "talus lateral length" EXACT [] is_a: FOVT:0000020 ! astragalus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0000014 name: obsolete talus medial depth def: "OBSOLETE The depth of the medial ridge of a trochlea of an astragalus along the anterior-posterior axis." [] comment: duplicate term synonym: "astragalus medial depth" EXACT [] synonym: "astragalus medial width AP" EXACT [] synonym: "talus medial width AP" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001043 [Term] id: FOVT:0000015 name: obsolete length of the lateral side of talus def: "OBSOLETE Length of the lateral side of an astragalus." [] comment: Redundant term property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0000013 [Term] id: FOVT:0000016 name: astragalus medial length def: "The length of the medial side of an astragalus (talus) along the proximal-distal axis." [ISBN:9780873659505] synonym: "astragalus greatest length of the medial half (GLm)" RELATED [ISBN:9780873659505] synonym: "talus medial length" EXACT [] is_a: FOVT:0000020 ! astragalus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0000017 name: astragalus distal articular breadth def: "The length an astragalus head (distal articular facet, facet for the navicular) along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: The points for this measurement are the medial-most point on the articular surface for the calcaneum on the astragalus (talus) to the lateral-most point of the trochleated head of an astragalus (talus). synonym: "astragalus breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] synonym: "astragalus distal articular breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "astragalus distal articular width" EXACT [] synonym: "talus distal articular breadth" EXACT [] is_a: FOVT:0000021 ! astragalus breadth intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:4200181 ! inheres in astragalus head relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:4200181 ! inheres in astragalus head property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000018 name: astragalus distal articular depth def: "The length of an astragalus head (distal articular facet, facet for the navicular)." [ISBN:9004086161\, 9789004086166] comment: This measurement is perpendicular to the astragalus distal articular breadth measurement. synonym: "astragalus distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "talus distal articular depth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:4200181 ! inheres in astragalus head relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:4200181 ! inheres in astragalus head property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000020 name: astragalus length {xref="ISBN:9780873659505"} def: "The length of an astragalus (talus) along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "astragalus greatest height (GH)" EXACT [ISBN:9780873659505] synonym: "astragalus maximal length (M1)" EXACT [ISBN:9004086161\, 9789004086166] synonym: "talus length" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002395 ! inheres in talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000021 name: astragalus breadth def: "The width of an astragalus (talus) along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "astragalus greatest breadth (GB)" RELATED [ISBN:9780873659505] synonym: "astragalus maximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "astragalus width" EXACT [] synonym: "talus breadth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0002395 ! inheres in talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000022 name: calcaneus length def: "The maximal length of a calcaneus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "calcaneus greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "calcaneus maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001450 ! inheres in calcaneus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000023 name: calcaneus distal breadth def: "The length of a distal end of a caclcaneus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This measurement is taken from the lateral side of the middle articular facet for talus of calcaneus to the medial side of the curboid facet of calcaneum. synonym: "calcaneus distal maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "calcaneus distal width" EXACT [] synonym: "calcaneus greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000025 name: tibia lateral length def: "The length of the lateral side of a tibia along the proximal-distal axis." [ISBN:9780873659505] synonym: "tibia length of the lateral part (LI)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004357 ! tibia length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000026 name: obsolete tibia diaphysis width def: "OBSOLETE The width of shaft or diaphysis of a tibia." [https://orcid.org/0000-0003-2699-3066] comment: unneeded term synonym: "tibia width" BROAD [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: OBA:VT1000289 [Term] id: FOVT:0000027 name: obsolete tibia proximal width def: "OBSOLETE The width of the proximal end of a tibia." [https://orcid.org/0000-0003-2699-3066] comment: not needed synonym: "breadth of proximal end of tibia" EXACT [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001006 [Term] id: FOVT:0000028 name: obsolete tibia distal width def: "OBSOLETE The width of the distal end of a tibia." [https://orcid.org/0000-0003-2699-3066] comment: not needed synonym: "breadth of distal end of tibia" EXACT [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001004 [Term] id: FOVT:0000029 name: obsolete tibia distal breadth def: "OBSOLETE The depth of the distal end of a tibia." [] comment: duplicate term synonym: "tibia distal width ML" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001004 [Term] id: FOVT:0000030 name: tooth row length def: "The length of a tooth row." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0002134 ! dentition size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0009678 ! inheres in tooth row relationship: RO:0000052 UBERON:0009678 ! inheres in tooth row property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0000032 name: snout-vent length def: "Body length from tip of nose (snout) to cloaca." [https://orcid.org/0000-0003-2699-3066] synonym: "body length without tail" RELATED [] synonym: "head-body length" RELATED [] is_a: OBA:VT0001256 ! body length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:8292 property_value: measured_in_taxon NCBITaxon:8504 [Term] id: FOVT:0001003 name: ear length to tragus def: "The length of a line of an ear from a helix of the outer ear to a tragus of an ear." [https://orcid.org/0000-0003-2699-3066] comment: This measurement is often taken in bats. is_a: OBA:0003426 ! external ear length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001004 name: tibia distal breadth def: "The length of a distal epiphysis of a tibia along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "tibia distal maximal breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "tibia distal width" EXACT [] is_a: OBA:1000196 ! distal epiphysis of tibia quality is_a: OBA:VT0000132 ! epiphysis width is_a: OBA:VT1000289 ! tibia width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004405 ! inheres in distal epiphysis of tibia relationship: RO:0000052 UBERON:0004405 ! inheres in distal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001005 name: tibia distal depth def: "The length of a distal epiphysis of a tibia along the anterior-posterior axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia depth of the distal end (Dd)" RELATED [] synonym: "tibia distal maximal depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003163 ! epiphysis size is_a: OBA:1000196 ! distal epiphysis of tibia quality is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004405 ! inheres in distal epiphysis of tibia relationship: RO:0000052 UBERON:0004405 ! inheres in distal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9979 [Term] id: FOVT:0001006 name: tibia proximal breadth def: "The length of a proximal epiphysis of a tibia along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "tibia proximal maximal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "tibia proximal width" EXACT [] is_a: OBA:0003298 ! proximal epiphysis of tibia size is_a: OBA:VT0000132 ! epiphysis width is_a: OBA:VT1000289 ! tibia width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0008772 ! inheres in proximal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001007 name: tibia proximal depth def: "The length of a proximal epiphysis of a tibia along the anterior-posterior axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166] synonym: "tibia proximal maximal depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003298 ! proximal epiphysis of tibia size is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0008772 ! inheres in proximal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001008 name: tibia diaphysis breadth def: "The length of a diaphysis of a tibia along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia diaphysis width" EXACT [] synonym: "tibia minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "tibia smallest diameter of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT1000289 ! tibia width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0013280 ! inheres in diaphysis of tibia relationship: RO:0000052 UBERON:0013280 ! inheres in diaphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001009 name: tibia diaphysis depth def: "The length of a diaphysis of a tibia along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "tibia minimal depth of diaphysis (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0013280 ! inheres in diaphysis of tibia relationship: RO:0000052 UBERON:0013280 ! inheres in diaphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001021 name: tibia medial length def: "The length of the medial side of a tibia along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "tibia medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004357 ! tibia length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001022 name: obsolete tibia greatest length def: "OBSOLETE The greatest length of a tibia from the proximal-most point of a tibia to the distal-most point of a tibia." [] {IAO:0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", IAO:0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: duplicate of a term in OBA property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: OBA:VT0004357 [Term] id: FOVT:0001023 name: tibia diaphysis circumference def: "The circumference of a diaphysis of a tibia." [ISBN:9780873659505] synonym: "tibia smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0013280 ! inheres in diaphysis of tibia relationship: RO:0000052 UBERON:0013280 ! inheres in diaphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001024 name: femur proximal breadth def: "The length of a proximal epiphysis of a femur along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "femur proximal maximal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur proximal width" EXACT [] is_a: OBA:0002389 ! proximal epiphysis of femur size is_a: OBA:VT0000132 ! epiphysis width is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004412 ! inheres in proximal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001025 name: femur trochanter breadth def: "The length of the lesser trochanter of femur along the medial-lateral axis." [ISBN:9780873659505] synonym: "femur breadth of the region of the trochanter tertius (BTr)" RELATED [ISBN:9780873659505] synonym: "femur trochanter width" EXACT [] is_a: OBA:0002863 ! lesser trochanter size is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0002504 ! inheres in lesser trochanter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001026 name: femur caput depth def: "The length of a head of femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur depth of the caput femoris (DC)" RELATED [ISBN:9780873659505] synonym: "femur maximal depth of caput femoris (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002864 ! head of femur size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0006767 ! inheres in head of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001027 name: femur diaphysis breadth def: "The length of a diaphysis of femur along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur diaphysis width" EXACT [] synonym: "femur minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0006862 ! inheres in diaphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0006862 ! inheres in diaphysis of femur property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001028 name: femur diaphysis circumference def: "The circumference of the diaphysis of a femur." [ISBN:9780873659505] synonym: "femur circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0010014 ! femur circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0006862 ! inheres in diaphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0006862 ! inheres in diaphysis of femur property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001029 name: femur distal breadth def: "The length of a distal epiphysis of a femur along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "femur distal maximal breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur distal width" EXACT [] is_a: OBA:0002726 ! distal epiphysis of femur size is_a: OBA:VT0000132 ! epiphysis width is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004406 ! inheres in distal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001030 name: femur proximal depth def: "The length of a proximal epiphysis of a femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "femur proximal maximal depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002389 ! proximal epiphysis of femur size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004412 ! inheres in proximal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001031 name: femur distal depth def: "The length of a distal epiphysis of a femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "femur distal maximal depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002726 ! distal epiphysis of femur size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004406 ! inheres in distal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001032 name: femur trochlea breadth def: "The length of the medial condyle (trochlea) of a femur along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "femur maximal breadth of the trochlea (M9)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur trochlea with" EXACT [] is_a: OBA:1000180 ! distal epiphysis of femur quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0009984 ! inheres in medial condyle of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0009984 ! inheres in medial condyle of femur property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001033 name: femur diaphysis depth def: "The length of a diaphysis of femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "femur diameter perpendicular to, and at the level of, femur diaphysis breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0006862 ! inheres in diaphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0006862 ! inheres in diaphysis of femur property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001034 name: humerus diaphysis breadth def: "The length of a diaphysis of humerus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus diaphysis width" EXACT [] synonym: "humerus minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002474 ! humerus diaphysis size is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004652 ! inheres in humerus diaphysis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001035 name: humerus proximal breadth def: "The length of a proximal epiphysis of a humerus along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is often measured at the epicondyles. synonym: "humerus breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "humerus proximal maximal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus proximal width" EXACT [] is_a: OBA:1000394 ! proximal epiphysis of humerus quality is_a: OBA:VT0000132 ! epiphysis width is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004411 ! inheres in proximal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004411 ! inheres in proximal epiphysis of humerus property_value: IAO:0000114 IAO:0000423 property_value: not_measured_in_taxon NCBITaxon:9611 property_value: not_measured_in_taxon NCBITaxon:9979 [Term] id: FOVT:0001036 name: humerus trochlea breadth def: "The length of a trochlea of a humerus along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus breadth of trochlea (BT)" RELATED [ISBN:9780873659505] synonym: "humerus maximal breadth of the trochlea (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus trochlea width" EXACT [] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0000144 ! inheres in trochlea of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0000144 ! inheres in trochlea of humerus property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001037 name: humerus distal depth def: "The length of a distal epiphysis of a humerus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus distal maximal depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003163 ! epiphysis size is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004404 ! inheres in distal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004404 ! inheres in distal epiphysis of humerus property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001038 name: humerus proximal depth def: "The length of a proximal epiphysis of a humerus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is measured at the level of the median tubercle. synonym: "humerus depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "humerus proximal depth at the level of the median turbecle (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003163 ! epiphysis size is_a: OBA:1000394 ! proximal epiphysis of humerus quality is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004411 ! inheres in proximal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004411 ! inheres in proximal epiphysis of humerus property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9979 [Term] id: FOVT:0001039 name: humerus distal breadth def: "The length of a distal epiphysis of a humerus along the medial-lateral axis." [ISBN:9780873659505] comment: This is often measured across the distal trochlea. {xref="ISBN:9780873659505"} synonym: "humerus breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "humerus distal trochlear breadth" EXACT [] synonym: "humerus distal width" EXACT [] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0000132 ! epiphysis width is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004404 ! inheres in distal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004404 ! inheres in distal epiphysis of humerus property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001040 name: humerus diaphysis depth def: "The length of the diaphysis of a humerus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus diameter perpendicular to, and at the level of, humerus diaphysis breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002474 ! humerus diaphysis size is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004652 ! inheres in humerus diaphysis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001041 name: obsolete astragalus width def: "OBSOLETE The width of an astragalus (talus)." [https://orcid.org/0000-0003-2699-3066] comment: same as astragalus breadth synonym: "talus width" EXACT [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0000021 [Term] id: FOVT:0001042 name: astragalus lateral depth def: "The length of the lateral side of an astragalus (talus) along the anterior-posterior axis." [ISBN:9780873659505] synonym: "astragalus depth of the lateral half (DI)" RELATED [ISBN:9780873659505] synonym: "talus lateral depth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0001043 name: astragalus medial depth def: "The length of the medial side of an astragalus (talus) along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "astragalus depth of medial half (DM)" RELATED [ISBN:9780873659505] synonym: "astragalus maximal medial depth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "talus medial depth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0001044 name: astragalus distal breadth def: "The length of the distal end of an astragalus (talus) along the medial-lateral axis." [DOI:10.1007/s00267-006-0240-8, ISBN:9780873659505] synonym: "astragalus AST4" RELATED [DOI:10.1007/s00267-006-0240-8] synonym: "astragalus breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "astragalus distal width" EXACT [] synonym: "talus distal breadth" EXACT [] is_a: FOVT:0000021 ! astragalus breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0001045 name: trochlea tali length def: "The length of the trochlea tali (medial condyle) of an astragulas (talus) along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "astragalus diameter of medial condyle" EXACT [] synonym: "astragalus length of the medial part of the trochlea tali (LmT)" RELATED [ISBN:9780873659505] synonym: "astragalus maximal diameter of the medial condyle (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "astragalus medial trochlea tali length" EXACT [] synonym: "talus medial condyle length" EXACT [] is_a: FOVT:0000020 ! astragalus length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:7500066 ! inheres in medial condyle of talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500066 ! inheres in medial condyle of talus property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001046 name: astragalus trochlea breadth def: "The length of the trochlea of an astragalus (talus) along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] {comment="ISBN:9780873659505"} synonym: "astragalus condylar breadth" EXACT [] synonym: "astragalus trochlea width" EXACT [] synonym: "atragalus breadth of the trochlea (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "talus condylar breadth" EXACT [] synonym: "talus trochlea breadth" EXACT [] is_a: FOVT:0000021 ! astragalus breadth intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:7500063 ! inheres in trochlea of talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500063 ! inheres in trochlea of talus property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001047 name: calcaneus proximal length def: "The length of the proximal end of a calcaneus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] comment: This measurement is from the posterior articular facet for talus of calcaneus to calcaneal tuber. synonym: "calcaneus length of the proximal part (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0000022 ! calcaneus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001048 name: calcaneus distal depth def: "The length of a distal end of a caclcaneus along the anterior-posterior axis." [https://ethnobiology.org/sites/default/files/pdfs/JoE/7-1/Purdue1987.pdf, ISBN:9004086161\, 9789004086166] comment: The anterior-most feature is the tubercle of calcaneus. synonym: "calcaneus distal maximal depth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "calcaneus lateral depth (CALD)" RELATED [https://eprints.nottingham.ac.uk/50198/] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001053 name: gutted body mass def: "The mass of a multicellur organism after removing internal organs." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001054 name: skinned body mass def: "The mass of a multicellular organism after being skinned." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001055 name: mass of skeleton def: "The mass of a multicellur organism skeletal elements (i.e., bones) without skin, internal organs, or other soft tissue." [https://orcid.org/0000-0003-2699-3066] synonym: "bone mass" RELATED [] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001056 name: gutted and skinned body mass def: "The mass of a mutlicellular organism after being both gutted (i.e., internal organs removed) and skinned." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001057 name: testis length def: "The length of a testis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001060 ! gonad length is_a: OBA:VT0001148 ! testes size trait intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0000473 ! inheres in testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001058 name: right testis length def: "The length of a testis on the right side." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001057 ! testis length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004534 ! inheres in right testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004534 ! inheres in right testis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001059 name: left testis length def: "The length of a testis on the left side." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001057 ! testis length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004533 ! inheres in left testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004533 ! inheres in left testis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001060 name: gonad length comment: The length of a gonad. {xref="https://orcid.org/0000-0003-2699-3066"} is_a: OBA:0002017 ! gonad size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0000991 ! inheres in gonad relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001061 name: humerus lateral length def: "The length of the lateral side of a humerus along the proximal-distal axis." [ISBN:9780873659505] comment: This measurement is from lateral tuberosity to lateral border of the trochlea. synonym: "humerus greatest length of lateral part (GLI)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004350 ! humerus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001062 name: ovary length def: "The length of an ovary." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001060 ! gonad length is_a: OBA:VT0001127 ! ovary size trait intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0000992 ! inheres in ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001063 name: right ovary length def: "The length of an ovary on the right side." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001062 ! ovary length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002118 ! inheres in right ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0002118 ! inheres in right ovary property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001064 name: left ovary length def: "The length of an ovary on the left side." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001062 ! ovary length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002119 ! inheres in left ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0002119 ! inheres in left ovary property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001065 name: anterior tibial tuberosity length def: "The length of the anterior tibial tuberosity (fossa digitalis) along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "tibia length of the fossa digitalis (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000148 ! proximal epiphysis of tibia quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: OBA:VT0004357 ! tibia length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:7500062 ! inheres in tibial tuberosity relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500062 ! inheres in tibial tuberosity property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001066 name: obsolete humerus proximal depth at median tubercle def: "OBSOLETE The length along the medial-lateral axis of the caput of the humerus." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: Redundant with another term synonym: "humerus proximal length AP at median tubercule" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001038 [Term] id: FOVT:0001067 name: humerus trochlear sulcus height def: "The length of the trochlear sulcus (trochlear groove) of a humerus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus minimal trochlear height (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:3000785 ! inheres in trochlear groove of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:3000785 ! inheres in trochlear groove of humerus property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001068 name: humerus medial trochlear height def: "The length of the distal medial trochlea of a humerus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus maximal trochlear height (H9)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus medial trochlear depth" EXACT [] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0000144 ! inheres in trochlea of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0000144 ! inheres in trochlea of humerus property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001069 name: humerus trochlear height at sagittal crest def: "The length of the sagittal crest of a trochlea of a humerus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus trochlear depth" EXACT [] synonym: "humerus trochlear depth at sagittal crest" EXACT [] synonym: "trochlear height at the sagittal creast (near the condyle) (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:7500061 ! inheres in trochlear ridge of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500061 ! inheres in trochlear ridge of humerus property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001070 name: femur length from caput to lateral condyle def: "The length from a head of femur (caput) to a lateral condyle of femur." [ISBN:9004086161\, 9789004086166] synonym: "femur greatest length from caput femoris (GLC)" RELATED [ISBN:9780873659505] synonym: "femur length from caput femoris to lateral condyle (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004348 ! femur length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001071 name: olecranon length def: "The length of an olecranon of an ulna along the proximal-distal axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "ulna length of the olecranon (LO)" RELATED [ISBN:9780873659505] synonym: "ulna length of the olecranon (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: OBA:VT0004370 ! ulna length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0006810 ! inheres in olecranon relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0006810 ! inheres in olecranon property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001072 name: ulna proximal articular breadth def: "The length of the humeral facet of an ulna along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "ulna facies articularis proximalis breadth" EXACT [] synonym: "ulna breadth across the coronoid process, breadth of the proximal articular surface (BPC)" RELATED [ISBN:9780873659505] synonym: "ulna coronoid process breadth" EXACT [] synonym: "ulna maximal articular breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "ulna proximal articula width" EXACT [] is_a: OBA:0002379 ! ulna size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:4200203 ! inheres in humeral facet on the ulna relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:4200203 ! inheres in humeral facet on the ulna property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001073 name: obsolete ulna width {xref="https://orcid.org/0000-0003-2699-3066"} comment: not needed relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001074 name: olecranon depth def: "The length of an olecranon of an ulna along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: Olecranon depth is often measured at the epicondyles. synonym: "ulna minimal depth of the olecranon (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "ulna smallest depth of the olecranon (SDO)" RELATED [ISBN:9780873659505] is_a: OBA:0002379 ! ulna size is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0006810 ! inheres in olecranon relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0006810 ! inheres in olecranon property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001075 name: ulna lateral length def: "The length of the lateral side of an ulna along the proximal-distal axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9780873659505] synonym: "ulna greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004370 ! ulna length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001076 name: ulna depth across the process anaconaeus def: "The length of the humeral facet of an ulna along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "depth across the processus anconaeus (M5) (DPA)" RELATED [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] is_a: OBA:0002379 ! ulna size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:4200203 ! inheres in humeral facet on the ulna relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:4200203 ! inheres in humeral facet on the ulna property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001077 name: length of astragalus along the midline def: "The length along the midline of an astragalus (talus) along the proximal-distal axis." [DOI:10.1007/s00267-006-0240-8] comment: This measurement is from the astragalus head (distal articular facet for the navicular) to sulcus tali. synonym: "astragalus AST3" RELATED [DOI:10.1007/s00267-006-0240-8] synonym: "length of talus along the midline" EXACT [] is_a: FOVT:0000020 ! astragalus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001078 name: breadth of calcaneal body def: "The length of a calcaneal body along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] comment: This is the narrowest section of the calcaneus. synonym: "calcaneus minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "width of calcaneal body" EXACT [] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:7500093 ! inheres in calcaneal body relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500093 ! inheres in calcaneal body property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001079 name: obsolete calcaneus width def: "OBSOLETE The width of a calcaneus." [https://orcid.org/0000-0003-2699-3066] comment: not needed synonym: "calcaneus breadth" EXACT [] synonym: "calcaneus CALD" EXACT [DOI:10.1007/s00267-006-0240-8] synonym: "calcaneus length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001080 name: calcaneus proximal breadth def: "The length of the proximal end of a calcaneus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "calcaneus proximal maximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "calcaneus proximal width" EXACT [] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001081 name: calcaneus proximal depth def: "The length of the proximal end of a calcaneus from a lateral tubercle of calcaneus to a medial tubercle of calcaneus." [ISBN:9004086161\, 9789004086166] synonym: "calcaneus maximal depth" EXACT [] synonym: "calcaneus proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001082 name: depth of calcaneal body def: "The length of a calcaneal body along the anterior-posterior axis." [https://eprints.nottingham.ac.uk/50198/] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:7500093 ! inheres in calcaneal body relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500093 ! inheres in calcaneal body property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001123 name: radius medial length def: "The length of the medial side of a radius along the proximal-distal axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166] synonym: "radius medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004355 ! radius length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001124 name: radius lateral length def: "The length of the lateral side of a radius along the proximal-distal axis." [ISBN:9780873659505] synonym: "radius length of the lateral part (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004355 ! radius length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001125 name: radius diaphysis breadth def: "The length of a diaphysis of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "radius diaphysis width" EXACT [] synonym: "radius minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000380 ! diaphysis of radius quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001028 ! inheres in diaphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001028 ! inheres in diaphysis of radius property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001126 name: radius diaphysis depth def: "The length of a diaphysis of a radius along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "radius depth of diaphysis at level of radius diaphysis breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000380 ! diaphysis of radius quality is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0001028 ! inheres in diaphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001028 ! inheres in diaphysis of radius property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001127 name: radius proximal articular breadth def: "The length of an articular surface on the proximal end of a radius that interacts with the humerus along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "proximal articular width" EXACT [] synonym: "radius greatest breadth of the facies articularis proximalis (humeral articular surface (BFp)" RELATED [ISBN:9780873659505] synonym: "radius proximal articular width" EXACT [] synonym: "radius proximal artiuclar breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:4200204 ! inheres in humeral facet on radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:4200204 ! inheres in humeral facet on radius property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001128 name: radius proximal articular depth def: "The length of an articular surface on the proximal end of a radius that interacts with a humerus along the anterior-posterior axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166] synonym: "radius proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:4200204 ! inheres in humeral facet on radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:4200204 ! inheres in humeral facet on radius property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001129 name: radius proximal breadth def: "The length of a proximal epiphysis of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "radius greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "radius proximal maximal breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius proximal width" EXACT [] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002496 ! epiphysis of radius size is_a: OBA:1000304 ! proximal epiphysis of radius quality is_a: OBA:VT0000132 ! epiphysis width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004413 ! inheres in proximal epiphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004413 ! inheres in proximal epiphysis of radius property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001130 name: radius distal articular breadth def: "The width along the medial-lateral axis of the distal end of a radius." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "radius distal articular width" EXACT [] synonym: "radius facies articularis distalis breadth (M8)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:7500080 ! inheres in articular surface for carpals relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500080 ! inheres in articular surface for carpals property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001131 name: radius distal articular depth def: "The length of the articular surface on the distal end of a radius that interacts with the carpals along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "radius distal articular depth (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:7500080 ! inheres in articular surface for carpals relationship: RO:0000052 UBERON:7500080 ! inheres in articular surface for carpals property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001132 name: radius distal breadth def: "The length of a distal epiphysis of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is often measured across the epicondyles. synonym: "radius distal maximal breadth (M10)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius distal width" EXACT [] synonym: "radius greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002716 ! distal epiphysis of radius size is_a: OBA:VT0000132 ! epiphysis width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004407 ! inheres in distal epiphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001133 name: radius length from the proximal articular surface to the distal articular surface def: "The length of a radius from the proximal articular surface to the distal articular surface." [ISBN:9780873659505] synonym: "radius physiological length (PL)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004355 ! radius length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001134 name: radius diaphysis circumference def: "The circumference of a diaphysis of a radius." [ISBN:9780873659505] synonym: "radius smallest circumference of diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000380 ! diaphysis of radius quality is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0001028 ! inheres in diaphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001028 ! inheres in diaphysis of radius property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001135 name: DEPRECATED metatarsal bone length comment: already in OBA relationship: seeAlso OBA:0004033 ! metatarsal bone length is_obsolete: true [Term] id: FOVT:0001136 name: obsolete metatarsal bone of digit 2 length def: "OBSOLETE The length of the metatarsal bone of digit 2 along the proximal-distal axis." [] {IAO:0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", IAO:0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-06-03T22:41:34Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0003272 [Term] id: FOVT:0001137 name: obsolete metatarsal bone of digit 3 length def: "OBSOLETE The length of a metatarsal bone of digit 3 along the proximal-distal axis." [] {IAO:0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", IAO:0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: class already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-06-03T22:44:56Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0002565 [Term] id: FOVT:0001138 name: obsolete metatarsal bone of digit 4 length def: "OBSOLETE The length of the metatarsal bone of digit 4 along the proximal-distal axis." [] {IAO:0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", IAO:0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: class already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-06-03T22:46:16Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0002567 [Term] id: FOVT:0001139 name: obsolete metatarsal bone of digit 5 length def: "OBSOLETE The length of a metatarsal bone of digit 5 along the proximal-distal axis." [] {IAO:0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: class already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-06-03T22:50:27Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0002569 [Term] id: FOVT:0001140 name: fused metatarsal bones 3 and 4 length def: "The length of a fused metatarsal bones 3 and 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest length (GL)" RELATED [ISBN:9780873659505] is_a: FOVT:0001143 ! fused metapodial bones 3 and 4 length is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001141 name: metapodial bone length def: "The length of a metapodial bone." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone" EXACT [] is_a: OBA:0002381 ! long bone length is_a: OBA:0005468 ! limb long bone morphology is_a: OBA:VT0000572 ! autopod morphology trait intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003821 ! inheres in metapodium bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003821 ! inheres in metapodium bone property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001142 name: metapodial bone of digit 2 length def: "The length of a metapodial bone of digit 2." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 2" EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001143 name: fused metapodial bones 3 and 4 length def: "The length of fused metapodial bones 3 and 4." [ISBN:9780873659505] synonym: "length of fused metapodial bones 3 and 4" EXACT [] is_a: FOVT:0001141 ! metapodial bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0013586 ! inheres in fused metapodial bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013586 ! inheres in fused metapodial bones 3 and 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001144 name: metapodial bone of digit 4 length def: "The length of a metapodial bone of digit 4." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 4" EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001145 name: metapodial bone of digit 5 length def: "The length of a metapodial bone of digit 5." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 5" EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001146 name: metapodial bone of digit 3 length def: "The length of a metapodial bone of digit 3." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 3." EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001147 name: obsolete radius width def: "OBSOLETE The width of a radius." [https://orcid.org/0000-0003-2699-3066] synonym: "radius breadth" EXACT [] synonym: "width of radius bone" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001148 name: obsolete radius distal width def: "OBSOLETE The width of the distal end of a radius." [https://orcid.org/0000-0003-2699-3066] comment: not needed relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001132 [Term] id: FOVT:0001149 name: obsolete radius proximal width def: "OBSOLETE The width of the proximal end of a radius." [https://orcid.org/0000-0003-2699-3066] comment: unneeded term relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-06-17T00:54:08Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001147 [Term] id: FOVT:0001150 name: obsolete radius proximal articular width def: "OBSOLETE The width of the arcitular surface that articulates with the humerus located on the proximal end of a radius." [https://orcid.org/0000-0003-2699-3066] comment: unneeded term relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-06-17T00:57:18Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001147 [Term] id: FOVT:0001151 name: obsolete fibula length def: "OBSOLETE The length of a fibula along the proximal-distal axis." [] {IAO:0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: Already exists in OBA. synonym: "length of fibula" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-07-22T21:20:50Z" xsd:dateTime is_obsolete: true replaced_by: OBA:VT0000482 [Term] id: FOVT:0001152 name: scapula dorsal length def: "The length of the dorsal side of a scapula along the proximal-distal axis." [ISBN:9780873659505] synonym: "scapula greatest dorsal length (Ld)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004340 ! scapula length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001153 name: scapula spine length def: "The length of a scapular spine along the proximal-distal axis." [ISBN:9780873659505] synonym: "scapula height along the spine (HS)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004340 ! scapula length is_a: OBA:VT0004347 ! scapular spine morphology trait intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004651 ! inheres in scapula spine relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004651 ! inheres in scapula spine property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001154 name: scapula neck breadth def: "The length of the neck of a scapula." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: In non-apes (not Hominoidea), this is measured along the medial-lateral axis; in Apes (Hominoidea) this is measured along the anterior-posterior axis. synonym: "collum scapulae length" EXACT [] synonym: "scapula minimal breadth at the neck (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "scapula neck width" EXACT [] synonym: "smallest length of the collum scapulae (SLC)" RELATED [ISBN:9780873659505] is_a: FOVT:0001157 ! scapula depth intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018667 ! inheres in neck of scapula relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018667 ! inheres in neck of scapula property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001155 name: glenoid cavity length def: "The length of a glenoid cavity." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: In non-anatomical humans (i.e., not Homo), this is measured along the anterior-posterior axis; in anatomical humans (Homo) this is measured along the superior-inferior (upper-lower) axis. synonym: "scapula articular maximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "scapula length of glenoid cavity (LG)" RELATED [ISBN:9780873659505] is_a: OBA:0002741 ! glenoid fossa size is_a: OBA:VT0004340 ! scapula length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0006657 ! inheres in glenoid fossa relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001156 name: glenoid cavity breadth def: "The length of a glenoid cavity (glenoid fossa) along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "scapula articular maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "scapula breadth of glenoid cavity (BG)" RELATED [ISBN:9780873659505] is_a: FOVT:0001157 ! scapula depth is_a: OBA:0002741 ! glenoid fossa size intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0006657 ! inheres in glenoid fossa relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001157 name: scapula depth def: "The depth of a scapula along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "scapula maximal depth of spina (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004343 ! scapula size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0006849 ! inheres in scapula relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001158 name: obsolete radius diaphysis width def: "OBSOLETE The width of the diaphysis of a radius." [ORCID: 0000-0003-2699-3066] comment: unneeded synonym: "IAO:0000423" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-07-27T23:38:42Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001147 [Term] id: FOVT:0001159 name: mass of viscera def: "The mass of the viscera (internal organs)." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001160 name: obsolete skin mass def: "OBSOLETE The mass of the skin of an organism." [] {IAO:0000119="ORCID: 0000-0003-2699-3066"} comment: IAO:0000423 comment: Term already exists. relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2021-07-27T23:59:50Z" xsd:dateTime is_obsolete: true replaced_by: OBA:VT1000425 [Term] id: FOVT:0001161 name: radial condyle breadth def: "The length of a radial condyle (styloid notch) of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "radial condyle width" EXACT [] synonym: "radial notch breadth" EXACT [] synonym: "radius breadth of the radial condyle (M11)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius lateral distal condyle breadth" EXACT [] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:7500078 ! inheres in styloid process of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500078 ! inheres in styloid process of radius property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001162 name: ulnar condyle breadth def: "The length of the ulnar codyle (ulnar notch) of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "medial distal condyle breadth" EXACT [] synonym: "radius breadth of the ulnar condyle (M12)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "ulnar condyle width" EXACT [] synonym: "ulnar notch breadth" EXACT [] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:7500079 ! inheres in ulnar notch of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500079 ! inheres in ulnar notch of radius property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001163 name: patella length def: "The length of a patella along the proximal-distal axis." [ISBN:9780873659505] synonym: "patella greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002386 ! patella size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002446 ! inheres in patella relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001164 name: patella breadth def: "The length of a patella along th medial-lateral axis." [ISBN:9780873659505] synonym: "patella greatest breadth (GB)" RELATED [ISBN:9780873659505] synonym: "patella width" EXACT [] is_a: OBA:0002386 ! patella size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0002446 ! inheres in patella relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001165 name: obsolete scapula lateral depth def: "OBSOLETE The length on the lateral edge of a scapula along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: does not exist relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001166 name: secondary molar tooth 1 occlusal surface width synonym: "molar tooth 1 length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018376 ! inheres in molar tooth 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018376 ! inheres in molar tooth 1 property_value: dcterms:description "The length of the occlusal surface of a molar tooth 1 along the medial-lateral axis." xsd:string {xref="https://orcid.org/0000-0003-2699-3066"} property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 1" xsd:string [Term] id: FOVT:0001167 name: obsolete upper molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a upper molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 1" xsd:string property_value: oboInOwl:editor_note "need to add upper molar tooth 1" xsd:string is_obsolete: true replaced_by: FOVT:0001169 [Term] id: FOVT:0001168 name: obsolete lower molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add lower molar tooth 1" xsd:string property_value: oboInOwl:editor_note "need to add secondary molar tooth 1" xsd:string is_obsolete: true replaced_by: FOVT:0001171 [Term] id: FOVT:0001169 name: upper secondary molar tooth 1 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1 length ML" EXACT [] is_a: FOVT:0001166 ! secondary molar tooth 1 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001170 name: obsolete upper primary molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001171 name: lower secondary molar tooth 1 occlusal surface width def: "The length of the occlusal surface of a lower secondary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1 length ML" EXACT [] is_a: FOVT:0001166 ! secondary molar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001172 name: obsolete lower primary molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001173 name: secondary molar tooth 1 occlusal surface length def: "The length of the occlusal surface of a molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0018376 ! inheres in molar tooth 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018376 ! inheres in molar tooth 1 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 1" xsd:string [Term] id: FOVT:0001174 name: obsolete upper molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] comment: redundant synonym: "upper molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 1" xsd:string is_obsolete: true replaced_by: FOVT:0001176 [Term] id: FOVT:0001175 name: obsolete lower molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of lower molar tooth 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] comment: redundant synonym: "lower molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 1" xsd:string is_obsolete: true replaced_by: FOVT:0001178 [Term] id: FOVT:0001176 name: upper secondary molar tooth 1 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001173 ! secondary molar tooth 1 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001177 name: obsolete upper primary molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001178 name: lower secondary molar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001173 ! secondary molar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001179 name: obsolete lower primary molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 1 along the anterior-posterior axis." [] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001180 name: secondary molar tooth 2 occlusal surface width def: "The length of the occlusal surface of a molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 2 occlusal surface length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018606 ! inheres in molar tooth 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018606 ! inheres in molar tooth 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 2" xsd:string [Term] id: FOVT:0001181 name: obsolete upper molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 2" xsd:string is_obsolete: true replaced_by: FOVT:0001183 [Term] id: FOVT:0001182 name: obsolete lower molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 2" xsd:string is_obsolete: true replaced_by: FOVT:0001185 [Term] id: FOVT:0001183 name: upper secondary molar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001180 ! secondary molar tooth 2 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001184 name: obsolete upper primary molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper secondary molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001185 name: lower secondary molar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower secondary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001180 ! secondary molar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001186 name: obsolete lower primary molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001187 name: secondary molar tooth 2 occlusal surface length def: "The length of the occlusal surface a molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 2 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0018606 ! inheres in molar tooth 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018606 ! inheres in molar tooth 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 2" xsd:string [Term] id: FOVT:0001188 name: obsolete upper molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 2" xsd:string is_obsolete: true replaced_by: FOVT:0001190 [Term] id: FOVT:0001189 name: obsolete lower molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 2" xsd:string is_obsolete: true replaced_by: FOVT:0001192 [Term] id: FOVT:0001190 name: upper secondary molar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001187 ! secondary molar tooth 2 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001191 name: obsolete upper primary molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001192 name: lower secondary molar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001187 ! secondary molar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001193 name: obsolete lower primary molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001194 name: secondary molar tooth 3 occlusal surface width def: "The length of the occlusal surface of molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 3 occlusal surface length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018377 ! inheres in molar tooth 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018377 ! inheres in molar tooth 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 3" xsd:string [Term] id: FOVT:0001195 name: obsolete upper molar tooth 3 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 3 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 3" xsd:string is_obsolete: true replaced_by: FOVT:0001197 [Term] id: FOVT:0001196 name: obsolete lower molar tooth 3 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 3 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 3" xsd:string is_obsolete: true replaced_by: FOVT:0001199 [Term] id: FOVT:0001197 name: upper secondary molar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001194 ! secondary molar tooth 3 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001198 name: DEPRECATED upper primary molar tooth 3 occlusal surface width comment: not a tooth is_obsolete: true [Term] id: FOVT:0001199 name: lower secondary molar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower secondary molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 3 occlusal length ML" EXACT [] is_a: FOVT:0001194 ! secondary molar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001200 name: secondary molar tooth 3 occlusal surface length def: "The length of the occlusal surface of a molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 3 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0018377 ! inheres in molar tooth 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018377 ! inheres in molar tooth 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 1" xsd:string [Term] id: FOVT:0001201 name: obsolete upper molar tooth 3 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 3 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 3" xsd:string is_obsolete: true replaced_by: FOVT:0001203 [Term] id: FOVT:0001202 name: obsolete lower molar tooth 3 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 3 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 3" xsd:string is_obsolete: true replaced_by: FOVT:0001204 [Term] id: FOVT:0001203 name: upper secondary molar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001200 ! secondary molar tooth 3 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001204 name: lower secondary molar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001200 ! secondary molar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001205 name: secondary molar tooth 4 occlusal surface width def: "The length of the occlusal surface of molar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 4 occlusal surface length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:7500055 ! inheres in molar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500055 ! inheres in molar tooth 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 4" xsd:string [Term] id: FOVT:0001206 name: obsolete upper molar tooth 4 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 4 along the medial-lateral surface." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 4 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 4" xsd:string is_obsolete: true replaced_by: FOVT:0001208 [Term] id: FOVT:0001207 name: obsolete lower molar tooth 4 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 4 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 4" xsd:string is_obsolete: true replaced_by: FOVT:0001209 [Term] id: FOVT:0001208 name: upper secondary molar tooth 4 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 4 along the medial-lateral axis." [] synonym: "upper secondary molar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001205 ! secondary molar tooth 4 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001209 name: lower secondary molar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower secondry molar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001205 ! secondary molar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001210 name: secondary molar tooth 4 occlusal surface length def: "The length of the occlusal surface of a molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 4 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:7500055 ! inheres in molar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500055 ! inheres in molar tooth 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 4" xsd:string [Term] id: FOVT:0001211 name: obsolete upper molar tooth 4 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 4 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 4" xsd:string is_obsolete: true replaced_by: FOVT:0001213 [Term] id: FOVT:0001212 name: obsolete lower molar tooth 4 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 4 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 4" xsd:string is_obsolete: true replaced_by: FOVT:0001214 [Term] id: FOVT:0001213 name: upper secondary molar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001210 ! secondary molar tooth 4 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001214 name: lower secondary molar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001210 ! secondary molar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001215 name: premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 1 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018294 ! inheres in premolar 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018294 ! inheres in premolar 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001216 name: upper premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001215 ! premolar tooth 1 occlusal surface width intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001217 name: lower premolar tooth 1 occlusal suface width def: "The length of the occlusal surface of a lower premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001215 ! premolar tooth 1 occlusal surface width intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001218 name: upper secondary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001219 name: upper primary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface or an upper primary premolar 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001220 name: lower secondary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001221 name: lower primary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001222 name: premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 1 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0018294 ! inheres in premolar 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018294 ! inheres in premolar 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001223 name: upper premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001224 name: lower premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001222 ! premolar tooth 1 occlusal surface length intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001225 name: upper secondary premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001223 ! upper premolar tooth 1 occlusal surface length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001226 name: lower secondary premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 1 occlusal tooth length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001227 name: lower primary premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001228 name: premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 2 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018640 ! inheres in premolar 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018640 ! inheres in premolar 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001229 name: upper premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001228 ! premolar tooth 2 occlusal surface width intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001230 name: lower premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001228 ! premolar tooth 2 occlusal surface width intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001231 name: upper secondary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001232 name: upper primary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper primary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001233 name: lower secondary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001234 name: lower primary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001235 name: premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 2 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0018640 ! inheres in premolar 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018640 ! inheres in premolar 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001236 name: upper premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 2 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001235 ! premolar tooth 2 occlusal surface length intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001237 name: lower premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001235 ! premolar tooth 2 occlusal surface length intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001238 name: upper secondary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001239 name: upper primary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 2 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001240 name: lower secondary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 2 occlusal surface along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001241 name: lower primary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 2 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001242 name: premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 3 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:7500056 ! inheres in premolar 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500056 ! inheres in premolar 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001243 name: upper premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001242 ! premolar tooth 3 occlusal surface width intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001244 name: lower premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001242 ! premolar tooth 3 occlusal surface width intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001245 name: upper secondary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001246 name: upper primary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper primary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001247 name: lower secondary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001248 name: lower primary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001249 name: premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 3 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:7500056 ! inheres in premolar 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500056 ! inheres in premolar 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001250 name: upper premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 3 along the anterior-posterior axis." [] synonym: "upper premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001249 ! premolar tooth 3 occlusal surface length intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001251 name: lower premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001249 ! premolar tooth 3 occlusal surface length intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001252 name: upper secondary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondry premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001253 name: upper primary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001254 name: lower secondary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001255 name: lower primary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 3 along the anterior-posterior reference." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001256 name: premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 4 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018647 ! inheres in premolar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018647 ! inheres in premolar tooth 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001257 name: upper premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001256 ! premolar tooth 4 occlusal surface width intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001258 name: lower premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001256 ! premolar tooth 4 occlusal surface width intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001259 name: upper secondary premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001260 name: upper primary premolar tooth 4 occlusal surface width def: "The length of the occlusal surfce of an upper primary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001261 name: lower secondary premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondry premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001262 name: lower primary premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001263 name: premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 4 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 4 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0018647 ! inheres in premolar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018647 ! inheres in premolar tooth 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001264 name: upper premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001263 ! premolar tooth 4 occlusal surface length intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001265 name: lower premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001263 ! premolar tooth 4 occlusal surface length intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001266 name: upper secondary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001267 name: upper primary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001268 name: lower secondary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001269 name: lower primary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001270 name: premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 4 length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018646 ! inheres in premolar tooth 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018646 ! inheres in premolar tooth 5 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001271 name: upper premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001270 ! premolar tooth 5 occlusal surface width intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001272 name: lower premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 5 occlusal suface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001270 ! premolar tooth 5 occlusal surface width intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001273 name: upper secondary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001274 name: upper primary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of an upper primary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001275 name: lower secondary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001276 name: lower primary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001277 name: premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 5 occlusal surfce length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0018646 ! inheres in premolar tooth 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018646 ! inheres in premolar tooth 5 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001278 name: upper premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001277 ! premolar tooth 5 occlusal surface length intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001279 name: lower premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001277 ! premolar tooth 5 occlusal surface length intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001280 name: upper secondary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001281 name: upper primary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001282 name: lower secondary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001283 name: lower primary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001284 name: upper tooth row length def: "The length of an upper tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper tooth row length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0000030 ! tooth row length intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001285 name: lower tooth row length def: "The length of a lower tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower tooth row length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0000030 ! tooth row length intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001286 name: canine tooth crown height def: "The height of a canine tooth crown along the superior-anterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "cuspid crown height" EXACT [] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0002100 ! tooth morphology trait is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001287 name: lower canine tooth crown height def: "The height of a lower canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower cuspid crown height" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018622 ! inheres in lower canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018622 ! inheres in lower canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001288 name: upper canine tooth crown height def: "The height of an upper canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper cuspid crown height" EXACT [] is_a: OBA:0003499 ! midface morphology is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018621 ! inheres in upper canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018621 ! inheres in upper canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001289 name: upper secondary canine tooth crown height def: "The height of an upper secondary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper seconday cuspid crown height" EXACT [] is_a: FOVT:0001288 ! upper canine tooth crown height is_a: FOVT:0001293 ! secondary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018561 ! inheres in upper secondary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018561 ! inheres in upper secondary canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001290 name: lower secondary canine tooth crown height def: "The height of a lower secondary canine tooth crown along the superior-inferior axis." [ISBN:9780873659505] comment: The measurement number and genus from von den Driesch (1979): 21 Canis, 17 Ursus. {xref="ISBN:9780873659505"} synonym: "height of the canine" EXACT [ISBN:9780873659505] synonym: "lower secondary cuspid crown height" EXACT [] is_a: FOVT:0001287 ! lower canine tooth crown height is_a: FOVT:0001293 ! secondary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018562 ! inheres in lower secondary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018562 ! inheres in lower secondary canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001291 name: upper primary canine tooth crown height def: "The height of an upper primary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary cuspid crown height" EXACT [] is_a: FOVT:0001288 ! upper canine tooth crown height is_a: FOVT:0001294 ! primary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018597 ! inheres in upper primary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018597 ! inheres in upper primary canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001292 name: lower primary canine tooth crown height def: "The height of a lower primary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary cuspid crown height" EXACT [] is_a: FOVT:0001287 ! lower canine tooth crown height is_a: FOVT:0001294 ! primary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018598 ! inheres in lower primary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018598 ! inheres in lower primary canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001293 name: secondary canine tooth crown height def: "The height of a secondary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "secondary cuspid crown height" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018584 ! inheres in secondary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018584 ! inheres in secondary canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001294 name: primary canine tooth crown height def: "The height of a primary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "primary cuspid crown height" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018583 ! inheres in primary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018583 ! inheres in primary canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001295 name: premolar tooth row length def: "The length of the occlusal surface of premolars along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0003215 ! premolar tooth morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001296 name: molar tooth row length def: "The length of the occlusal surface of molars along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001300 ! upper molar tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001297 name: upper premolar tooth row length def: "The length of an upper premolar tooth row along the anterior-posterior length." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0003215 ! premolar tooth morphology is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001298 name: lower premolar tooth row length def: "The length of a lower premolar tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001285 ! lower tooth row length is_a: OBA:0002710 ! premolar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001299 name: lower molar tooth row length def: "The length of a lower molar tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001285 ! lower tooth row length is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001300 name: upper molar tooth row length def: "The length of an upper tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0000030 ! tooth row length is_a: OBA:VT0002689 ! molar morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001301 name: canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of a canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "canine tooth diameter AP" EXACT [] synonym: "cuspid diameter AP" EXACT [] synonym: "cuspid tooth anterior-posterior diameter" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0003674 ! inheres in cuspid property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001302 name: upper canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of an upper canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper canine tooth diameter AP" EXACT [] synonym: "upper cuspid anterior-posterior diameter" EXACT [] synonym: "upper cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001303 name: lower canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of a lower canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower canine tooth diameter AP" EXACT [] synonym: "lower cuspid anterior-posterior diameter" EXACT [] synonym: "lower cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001304 name: upper secondary canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of an upper secondary canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: The measurement number and genus from von den Driesch (1979): 21 Sus {xref="ISBN:9780873659505"} synonym: "greatest diameter of the canine alveolus" EXACT [] synonym: "upper secondary canine tooth diameter AP" EXACT [] synonym: "upper secondary cuspid anterior-posterior diameter" EXACT [ISBN:9780873659505] synonym: "upper secondary cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001305 name: lower secondary canine anterior-posterior diameter def: "The diameter at the base (alveoli) of a lower secondary canine tooth along the anterior-posterior diameter." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondaray canine tooth diameter AP" EXACT [] synonym: "lower secondry cuspid anterior-posterior diameter" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001306 name: upper primary canine anterior-posterior diameter def: "The diameter at the base (alveoli) of an upper primary canine tooth along the anterior-posterior diameter." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary canine tooth diameter AP" EXACT [] synonym: "upper primary cuspid anterior-posterior diameter" EXACT [] synonym: "upper primary cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:0002703 ! primary dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001307 name: lower primary canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of a lower primary canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary canine tooth diameter AP" EXACT [] synonym: "lower primary cuspid anterior-posterior diameter" EXACT [] synonym: "lower primary cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:0002703 ! primary dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001308 name: canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "canine tooth diameter ML" EXACT [] synonym: "cuspid diameter ML" EXACT [] synonym: "cuspid medial-lateral diameter" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0003674 ! inheres in cuspid property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001309 name: upper canine tooth medial-lateral diameter def: "The diameter at a base (alveoli) of an upper canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: The measurement number and genus from von den Driesch (1979): 27 Felis synonym: "cuspid diameter ML" EXACT [] synonym: "upper canine tooth diameter AP" EXACT [] synonym: "upper cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001310 name: lower canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a lower canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower canine tooth diameter ML" EXACT [] synonym: "lower cuspid diameter ML" EXACT [] synonym: "lower cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001311 name: upper secondary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of an upper secondary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: The measurement number and genus from von den Driesch (1979): 27 Felis {xref="ISBN:9780873659505"} synonym: "breadth of the canine alveoli" EXACT [ISBN:9780873659505] synonym: "upper secondary canine tooth diameter ML" EXACT [] synonym: "upper secondary cuspid diameter ML" EXACT [] synonym: "upper secondary cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001312 name: lower secondary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a lower secondary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary canine tooth diameter ML" EXACT [] synonym: "lower secondary cuspid diameter ML" EXACT [] synonym: "lower secondary cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001313 name: upper primary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of an upper primary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary canine tooth diameter ML" EXACT [] synonym: "upper primary cuspid diameter ML" EXACT [] synonym: "upper primary cuspid medial-lateral diameter" EXACT [] is_a: OBA:0003499 ! midface morphology is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018583 ! inheres in primary canine tooth relationship: RO:0000052 UBERON:0018621 ! inheres in upper canine tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001314 name: lower primary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a lower primary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary canine tooth diameter ML" EXACT [] synonym: "lower primary cuspid diameter ML" EXACT [] synonym: "lower primary cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:0002703 ! primary dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: oboInOwl:editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string [Term] id: FOVT:0001315 name: upper left tooth row length def: "The length of a tooth row on the left side along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper left tooth row length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001316 name: upper right tooth row length def: "The length of an upper tooth row on the right side along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper right tooth row length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001317 name: molar tooth 1-2 length def: "The length of molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001318 name: molar tooth 1-3 length def: "The length of molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001319 name: molar tooth 1-4 length def: "The length of molar teeth 1-4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1-4 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001320 name: upper molar tooth 1-2 length def: "The length of upper molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001321 name: lower molar tooth 1-2 length def: "The length of lower molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001322 name: upper secondary molar tooth 1-2 length def: "The length of upper secondary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001176 ! upper secondary molar tooth 1 occlusal surface length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001323 name: lower secondary molar tooth 1-2 length def: "The length of lower secondary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001345 ! lower secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001324 name: obsolete upper primary molar tooth 1-2 length def: "OBSOLETE. The length of upper primary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1-2 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001325 name: obsolete lower primary molar tooth 1-2 length def: "OBSOLETE. The length of lower primary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1-2 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001326 name: upper molar tooth 1-3 length def: "The length of upper molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001327 name: lower molar tooth 1-3 length def: "The length of lower molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001328 name: upper secondary molar tooth 1-3 length def: "The length of upper secondary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001176 ! upper secondary molar tooth 1 occlusal surface length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001329 name: lower secondary molar tooth 1-3 length def: "The length of lower secondary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001345 ! lower secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001330 name: obsolete upper primary molar tooth 1-3 length def: "OBSOLETE. The length of upper primary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1-3 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001331 name: obsolete lower primary molar tooth 1-3 length def: "OBSOLETE. The length of lower primary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1-3 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001332 name: upper molar tooth 1-4 length def: "The length of upper molar teeth 1-4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper molar tooth 1-4 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001333 name: lower molar tooth 1-4 length def: "The length of lower molar teeth 1-4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower molar tooth 1-4 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001334 name: premolar tooth 4 to molar tooth 3 length def: "The length of premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar 4 to molar 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001335 name: upper premolar tooth 4 to molar tooth 3 length def: "The length of upper premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [] synonym: "upper premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001336 name: lower premolar tooth 4 to molar tooth 3 length def: "The length of lower premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001337 name: upper secondary premolar tooth 4 to molar tooth 3 length def: "The length of upper secondary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001344 ! upper secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001338 name: upper primary premolar tooth 4 to molar tooth 3 length def: "The length of upper primary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001339 name: lower secondary premolar tooth 4 to molar tooth 3 length def: "The length of lower secondary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001300 ! upper molar tooth row length is_a: FOVT:0001345 ! lower secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001340 name: lower primary premolar tooth 4 to molar tooth 3 length def: "The length of lower primary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001341 name: canine tooth to premolar tooth 3 length def: "The length of canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "cuspid to premolar tooth 3 length" EXACT [] synonym: "cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001342 name: upper canine tooth to premolar tooth 3 length def: "The length of upper canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "upper cuspid to premolar tooth 3 length" EXACT [] synonym: "upper cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001343 name: lower canine tooth to premolar tooth 3 length def: "The length of lower canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "lower cuspid to premolar tooth 3 length" EXACT [] synonym: "lower cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001344 name: upper secondary canine tooth to premolar tooth 3 length def: "The length of upper secondary canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "upper secondary cuspid to premolar tooth 3 length AP" EXACT [] synonym: "upper secondary cuspid tooth to premolar tooth 3 length" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001345 name: lower secondary canine tooth to premolar tooth 3 length def: "The length of lower secondary canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "lower secondary cuspid to premolar tooth 3 length" EXACT [] synonym: "lower secondary cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001346 name: diastema between central incisors length def: "The length of diastema between central incisors along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:2030002 ! diastema size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0035115 ! inheres in diastema between central incisors relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0035115 ! inheres in diastema between central incisors property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001347 name: diastema between lower central incisors length def: "The length of diastema between lower central incisors along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001346 ! diastema between central incisors length is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001346 ! diastema between central incisors length intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001348 name: upper secondary premolar tooth 3 crown height def: "The height of an upper secondary premolar tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001349 name: upper secondary premolar tooth 4 crown height def: "The length of an upper secondary premolar tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0002710 ! premolar tooth size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0016452 ! inheres in upper secondary premolar tooth property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001350 name: lower premolar tooth 3 anterior width def: "The length of the anterior side of a lower premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 anterior length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001351 name: lower premolar tooth 3 posterior width def: "The length of the posterior side of a lower premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 posterior length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001354 name: metacarpal bone of digit 3 diaphysis depth def: "The length of the diaphysis of a metacarpal bone of digit 3 along the anterior-posterior axis" [ISBN:9004086161\, 9789004086166] synonym: "metacarpal III smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] synonym: "third metacarpal depth of the diaphysis at the level of M3 (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002097 ! metacarpal bone diaphysis depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001355 name: metacarpal bone of digit 3 diaphysis breadth def: "The length of the shaft of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal III smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third metacarpal miniaml breadth (near the middle of the body) (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002102 ! metacarpal bone diaphysis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001356 name: metacarpal bone of digit 3 proximal articular breadth def: "The length of the articular surface on the proximal end of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal III distal breadth (Bd)" RELATED [ISBN:9780873659505] synonym: "metacarpal III proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001357 name: metacarpal bone of digit 3 distal articular breadth def: "The length of the articular surface on the distal end of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001358 name: metacarpal bone of digit 3 lateral condyle depth def: "The length of the lateral condyle on the distal end of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal minimal depth of the lateral condyle (13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001359 name: pelvis length def: "The length of a pelvis along the proximal-distal axis." [ISBN:9780873659505] synonym: "pelvis greatest length of one half (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0007830 ! inheres in pelvic girdle bone/zone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001360 name: acetabulum length (including the lip) def: "The length of an acetabulum along the upper-lower axis." [ISBN:9780873659505] comment: This measurement includes the lip of the acetabulum. synonym: "length of the acetabulum including the lip (LA)" RELATED [ISBN:9780873659505] is_a: OBA:0002413 ! pelvic girdle bone/zone size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001361 name: acetabulum length (to the rim) def: "The length of an acetabulum up to the rim of an acetabulum along the upper-lower axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This measurement does not include the lip. synonym: "diameter of the acetabulum (M1)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "length of the acetabulum to the rim (LAR)" RELATED [ISBN:9780873659505] is_a: OBA:0002413 ! pelvic girdle bone/zone size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001362 name: pubic symphysis length def: "The length of a pubic symphysis along the proximal-distal axis." [ISBN: 9780873659505] comment: This is only measured when the two halves of the pubis are fused. synonym: "length of the symphysis (LS)" RELATED [ISBN:9780873659505] is_a: FOVT:0001359 ! pelvis length is_a: OBA:0002395 ! pubic symphysis size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003699 ! inheres in pubic symphysis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001363 name: ilial shaft height def: "The length of an ilial shaft along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "smallest height of the shaft of ilium (SH)" RELATED [ISBN:9780873659505] is_a: FOVT:0001359 ! pelvis length is_a: OBA:0002162 ! ilium size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:3000774 ! inheres in ilial shaft relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:3000774 ! inheres in ilial shaft property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001364 name: ilial shaft breadth def: "The length of an ilial shaft along the medial-lateral axis." [ISBN:9780873659505] synonym: "ilial shaft width" EXACT [] synonym: "smallest breadth of the shaft of ilium (SB)" RELATED [ISBN:9780873659505] is_a: OBA:0002162 ! ilium size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:3000774 ! inheres in ilial shaft relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:3000774 ! inheres in ilial shaft property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001365 name: scapula lateral breadth def: "The length of the articular process on the lateral end of a scapula along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is measured from the articular process. synonym: "scapula geatest length of the processus articularis (glenoid process) (GLP)" RELATED [ISBN:9780873659505] synonym: "scapula maximal breadth of the articular process (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001157 ! scapula depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001366 name: obsolete right testis length def: "OBSOLETE The length of a testis on the right side." [https://orcid.org/0000-0003-2699-3066] comment: made an error, made new term synonym: "testis length" RELATED [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2022-05-05T23:24:47Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001058 [Term] id: FOVT:0001367 name: obsolete right testis length comment: made error, term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2022-05-05T23:27:11Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001058 [Term] id: FOVT:0001368 name: testis width def: "The width of a testis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001369 ! gonad width is_a: OBA:VT0001148 ! testes size trait intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0000473 ! inheres in testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001369 name: gonad width def: "The width of a gonad." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0002017 ! gonad size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0000991 ! inheres in gonad relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001370 name: obsolete right ovary length def: "OBSOLETE The length of an ovary on the right side." [https://orcid.org/0000-0003-2699-3066] comment: didn't realize the term already existed synonym: "ovary length" RELATED [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dcterms-date "2022-05-05T23:45:43Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001063 [Term] id: FOVT:0001371 name: ovary width def: "The width of an ovary." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001369 ! gonad width is_a: OBA:VT0001127 ! ovary size trait intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0000992 ! inheres in ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001372 name: ilial shaft circumference def: "The circumference of an ilial shaft." [ISBN:9780873659505] synonym: "smallest circumference of the shaft of ilium (SC)" RELATED [ISBN:9780873659505] is_a: OBA:0002162 ! ilium size is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:3000774 ! inheres in ilial shaft relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:3000774 ! inheres in ilial shaft property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001373 name: foramen obturatum length def: "The length of a formaen obturatum along the proximal-distal axis." [ISBN:9780873659505] synonym: "inner foramen obturatum length (LFo)" RELATED [ISBN:9780873659505] is_a: FOVT:0001359 ! pelvis length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0006803 ! inheres in obturator foramen relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0006803 ! inheres in obturator foramen property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001374 name: tubera coxarum breadth def: "The length of a tubera coxarum." [ISBN:9780873659505] synonym: "greatest breadth across the tubera coxarum (GBTc)" RELATED [ISBN:9780873659505] synonym: "tubera coxarum width" EXACT [] is_a: OBA:0002413 ! pelvic girdle bone/zone size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001375 name: acetabula breadth def: "The length of an acetabula along the medial-lateral axis." [ISBN:9780873659505] synonym: "acetablua width" EXACT [] synonym: "greatest breadth across the acetabula (GBA)" RELATED [ISBN:9780873659505] is_a: OBA:0002412 ! acetabular part of hip bone size is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001269 ! inheres in acetabular part of hip bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001376 name: tubera ischiadica breadth def: "The length of an ischial tuberosity along the medial-lateral axis." [ISBN:9780873659505] synonym: "greatest breadth across the tubera ischiadica (GBTi)" RELATED [ISBN:9780873659505] synonym: "tubera ischiadica width" EXACT [] is_a: FOVT:0001359 ! pelvis length is_a: OBA:0002391 ! ischium size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0034983 ! inheres in ischial tuberosity relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0034983 ! inheres in ischial tuberosity property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001377 name: ischia breadth def: "The length across both ischia along the medial-lateral axis." [ISBN:9780873659505] synonym: "ischia width" EXACT [] synonym: "smallest breadth across the bodies of the ischia (SBI)" RELATED [ISBN:9780873659505] is_a: OBA:0002391 ! ischium size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001274 ! inheres in ischium relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001378 name: calcaneus lateral depth def: "The length of the lateral side of a calcaneus along the proximal-distal axis." [https://ethnobiology.org/sites/default/files/pdfs/JoE/7-1/Purdue1987.pdf] synonym: "lateral depth of the calcaneum (CALD)" RELATED [https://ethnobiology.org/sites/default/files/pdfs/JoE/7-1/Purdue1987.pdf] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001379 name: forearm length def: "The length of a forearm." [DOI:10.1080/00445096.1965.11447303] comment: This is measured from the end of the ulna to the end of the carpus. {xref="DOI:10.1080/00445096.1965.11447303"} synonym: "fore-arm length" EXACT [] is_a: OBA:VT0010023 ! forelimb length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001380 name: secondary molar tooth 1 crown height def: "The height of a secondary molar tooth 1 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: need to add secondary molar tooth 1 is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018376 ! inheres in molar tooth 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018376 ! inheres in molar tooth 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001381 name: upper secondary molar tooth 1 crown height def: "The height of an upper molar tooth 1 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: need to add secondary molar tooth 1 synonym: "M1 crown height" EXACT [] is_a: FOVT:0001380 ! secondary molar tooth 1 crown height is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001380 ! secondary molar tooth 1 crown height intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001382 name: lower secondary molar tooth 1 crown height def: "The height of a lower molar tooth 1 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: need to add secondary molar tooth 1 synonym: "m1 crown height" EXACT [] is_a: FOVT:0001380 ! secondary molar tooth 1 crown height is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001380 ! secondary molar tooth 1 crown height intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001383 name: secondary molar tooth 2 crown height def: "The height of a secondary molar tooth 2 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018606 ! inheres in molar tooth 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018606 ! inheres in molar tooth 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 2" xsd:string [Term] id: FOVT:0001384 name: lower secondary molar tooth 2 crown height def: "The height of a lower secondary molar tooth 2 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "m2 crown height" EXACT [] is_a: FOVT:0001383 ! secondary molar tooth 2 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001385 name: upper secondary molar tooth 2 crown height def: "The height of an upper secondary molar tooth 2 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "M2 crown height" EXACT [] is_a: FOVT:0001383 ! secondary molar tooth 2 crown height is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001386 name: secondary molar tooth 3 crown height def: "The height of a secondary molar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018377 ! inheres in molar tooth 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018377 ! inheres in molar tooth 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add secondary molar tooth 3 to logical definition" xsd:string [Term] id: FOVT:0001387 name: lower secondary molar tooth 3 crown height def: "The height of a lower secondary molar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "m3 crown height" EXACT [] is_a: FOVT:0001386 ! secondary molar tooth 3 crown height is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001386 ! secondary molar tooth 3 crown height intersection_of: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001388 name: upper secondary molar tooth 3 crown height def: "The height of an upper secondary molar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "M3 crown height" EXACT [] is_a: FOVT:0001386 ! secondary molar tooth 3 crown height is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: FOVT:0001386 ! secondary molar tooth 3 crown height intersection_of: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001389 name: lower secondary molar tooth 1 trigonid width def: "The width of a lower secondary molar tooth 1 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001390 name: lower secondary molar tooth 1 trigonid length def: "The length of a lower secondary molar tooth 1 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001391 name: lower secondary molar tooth 1 talonid width def: "The width of a lower secondary molar tooth 1 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001392 name: lower secondary molar tooth 1 talonid length def: "The lenght of a lower secondary molar tooth 1 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001393 name: lower secondary molar tooth 2 trigonid width def: "The widht of a lower secondary molar tooth 2 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001394 name: lower secondary molar tooth 2 trigonid length def: "The length of a lower secondary molar tooth 2 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001395 name: lower secondary molar 2 talonid width def: "The widht of a lower secondary molar 2 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001396 name: lower secondary molar tooth 2 talonid length def: "The length of a lower secondary molar tooth 2 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001397 name: lower secondary molar tooth 3 trigonid width def: "The width of a lower secondary molar tooth 3 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001398 name: lower secondary molar tooth 3 trigonid length def: "The length of a lower secondary molar tooth 3 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001399 name: lower secondary molar tooth 3 talonid width def: "The width of a lower secondary molar tooth 3 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001400 name: lower secondary molar tooth 3 talonid length def: "The length of a lower secondary molar tooth 3 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001401 name: lower secondary molar tooth 4 trigonid width def: "The width of a lower secondary molar tooth 4 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001402 name: lower secondary molar tooth 4 trigonid length def: "The length of a lower secondary molar tooth 4 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonid" xsd:string [Term] id: FOVT:0001403 name: lower secondary molar tooth 4 talonid width def: "The width of a lower secondary molar tooth 4 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001404 name: lower secondary molar tooth 4 talonid length def: "The length of a lower secondary molar tooth 4 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add talonid" xsd:string [Term] id: FOVT:0001405 name: premolar tooth 3 crown height def: "The height of a premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:7500056 ! inheres in premolar 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:7500056 ! inheres in premolar 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001406 name: upper premolar tooth 3 crown height def: "The height of an upper premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001407 name: lower premolar tooth 3 crown height def: "The height of a lower premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001408 name: obsolete upper secondary premolar tooth 3 crown height def: "OBSOLETE. The height of an upper secondary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001348 [Term] id: FOVT:0001409 name: lower secondary premolar tooth 3 crown height def: "The height of a secondary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001410 name: upper primary premolar tooth 3 crown height def: "The height of an upper primary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0002703 ! primary dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001411 name: lower primary premolar tooth 3 crown height def: "The height of a lower primary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0002703 ! primary dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001500 name: incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 1 (central incisor) tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "central incisor anterior-posterior diameter" EXACT [] synonym: "central incisor diameter AP" EXACT [] synonym: "incisor 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0018551 ! inheres in incisor tooth 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001501 name: upper incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of an upper incisor tooth 1 (central incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper central incisor anterior-posterior diameter" EXACT [] synonym: "upper central incisor diameter AP" EXACT [] synonym: "upper incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0018603 ! inheres in upper central incisor tooth property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001502 name: lower incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of a lower incisor tooth 1 (central incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower central incisor anterior-posterior diameter" EXACT [] synonym: "lower central incisor diameter AP" EXACT [] synonym: "lower incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0018601 ! inheres in lower central incisor tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string [Term] id: FOVT:0001503 name: upper secondary incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 1 (central incisor) along the anterior-posterior axis." [] synonym: "I1 anterior-posterior diameter" EXACT [] synonym: "I1 diameter AP" EXACT [] synonym: "upper secondary central incisor anterior-posterior diameter" EXACT [] synonym: "upper secondary central incisor diameter AP" EXACT [] synonym: "upper secondary incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018603 ! inheres in upper central incisor tooth property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001504 name: lower secondary incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 1 (central incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i1 anterior-posterior diameter" EXACT [] synonym: "i1 diameter AP" EXACT [] synonym: "lower secondary central incisor anterior-posterior diameter" EXACT [] synonym: "lower secondary central incisor diameter AP" EXACT [] synonym: "lower secondary incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018601 ! inheres in lower central incisor tooth property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string [Term] id: FOVT:0001505 name: incisor tooth 1 medial-lateral diameter def: "The diameter at the base of a incisor tooth 1 (central incisor) along the medial-lateral axis." [] synonym: "central incisor diameter ML" EXACT [] synonym: "central incisor medial-lateral diameter" EXACT [] synonym: "incisor tooth 1 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0018551 ! inheres in incisor tooth 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001506 name: upper secondary incisor tooth 1 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I1 diameter ML" EXACT [] synonym: "I1 medial-lateral diameter" EXACT [] synonym: "upper secondary central incisor diameter ML" EXACT [] synonym: "upper secondary central tooth medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 1 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018551 ! inheres in incisor tooth 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001507 name: lower secondary incisor tooth 1 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 1 (central incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i1 diameter ML" EXACT [] synonym: "i1 medial-lateral diameter" EXACT [] synonym: "lower secondary central incisor diameter ML" EXACT [] synonym: "lower secondary central incisor medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 1 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018551 ! inheres in incisor tooth 1 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string [Term] id: FOVT:0001508 name: incisor tooth 1 crown height def: "The height of an incisor tooth 1 (central incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "central incisor crown height" EXACT [] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018551 ! inheres in incisor tooth 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018551 ! inheres in incisor tooth 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001509 name: upper secondary incisor tooth 1 crown height def: "The height of an upper secondary incisor tooth (central incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I1 crown height" EXACT [] synonym: "upper secondary central incisor crown height" EXACT [] is_a: FOVT:0001508 ! incisor tooth 1 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001510 name: lower secondary incisor tooth 1 crown height def: "The height of a lower secondary incisor tooth 1 (central incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i1 crown height" EXACT [] synonym: "lower secondary central incisor crown height" EXACT [] is_a: FOVT:0001508 ! incisor tooth 1 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001511 name: incisor tooth 2 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 2 (lateral incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 2 diameter AP" EXACT [] synonym: "lateral incisor tooth anterior-posterior diameter" EXACT [] synonym: "lateral incisor tooth diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001512 name: upper secondary incisor tooth 2 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 2 (lateral incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I2 anterior-posterior diameter" EXACT [] synonym: "I2 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 2 diameter AP" EXACT [] synonym: "upper secondary lateral incisor anterior-posterior diameter" EXACT [] synonym: "upper secondary lateral incisor diameter AP'has exact synonym'" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001513 name: lower secondary incisor tooth 2 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 2 (lateral incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i2 anterior-posterior diameter" EXACT [] synonym: "i2 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 2 diameter AP" EXACT [] synonym: "lower secondary lateral incisor anterior-posterior diameter" EXACT [] synonym: "lower secondary lateral incisor diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string [Term] id: FOVT:0001514 name: incisor tooth 2 medial-lateral diameter def: "The diameter at the base of an incisor tooth 2 (lateral incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 2 diameter ML" EXACT [] synonym: "lateral incisor diameter ML'has exact synonym'" EXACT [] synonym: "lateral incisor medial-lateral diameter" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001515 name: upper secondary incisor tooth 2 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 2 (lateral incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I2 diameter ML" EXACT [] synonym: "I2 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 2 diameter ML" EXACT [] synonym: "upper secondary lateral incisor diameter ML" EXACT [] synonym: "upper secondary lateral incisor medial-lateral diameter" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001516 name: lower secondary incisor tooth 2 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 2 (lateral incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i2 diameter ML" EXACT [] synonym: "i2 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 2 diameter ML" EXACT [] synonym: "lower secondary lateral incisor diameter ML" EXACT [] synonym: "lower secondary lateral incisor medial-lateral diameter" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition relationship: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string [Term] id: FOVT:0001517 name: incisor tooth 2 crown height def: "The height of an incisor tooth 2 (lateral incisor) along the superior-inferior axis." [] synonym: "lateral incisor crown height" EXACT [] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018552 ! inheres in incisor tooth 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001518 name: upper secondary incisor tooth 2 crown height def: "The height of an upper secondary incisor tooth 2 (lateral incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I2 crown height" EXACT [] synonym: "upper secondary lateral incisor crown height" EXACT [] is_a: FOVT:0001517 ! incisor tooth 2 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001519 name: lower secondary incisor tooth 2 crown height def: "The height of a lower secondary incisor tooth (lateral incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i2 crown height" EXACT [] synonym: "lower secondary lateral incisor crown height" EXACT [] is_a: FOVT:0001517 ! incisor tooth 2 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001520 name: incisor tooth 3 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 3 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001521 name: upper secondary incisor tooth 3 anterior-posteior diameter def: "The diameter of an upper secondary incisor tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I3 anterior-posterior diameter" EXACT [] synonym: "I3 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 3 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001522 name: lower secondary incisor tooth 3 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 3 along the anterior-posterior axis." [] synonym: "i3 anterior-posterior diameter" EXACT [] synonym: "i3 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 3 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001523 name: incisor tooth 3 medial-lateral diameter def: "The diameter at the base of an incisor tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 3 diamter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001524 name: upper secondary incisor tooth 3 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I3 diameter ML" EXACT [] synonym: "I3 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 3 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001525 name: lower secondary incisor tooth 3 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i3 diameter ML" EXACT [] synonym: "i3 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 3 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001526 name: incisor tooth 3 crown height def: "The height of an incisor tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001527 name: upper secondary incisor tooth 3 crown height def: "The height of an upper secondary incisor tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I3 crown height" EXACT [] is_a: FOVT:0001526 ! incisor tooth 3 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001528 name: lower secondary incisor tooth 3 crown height def: "The height of a lower secondary incisor tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i3 crown height" EXACT [] is_a: FOVT:0001526 ! incisor tooth 3 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 3" xsd:string [Term] id: FOVT:0001529 name: incisor tooth 4 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 4 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001530 name: upper secondary incisor tooth 4 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I4 anterior-posterior diameter" EXACT [] synonym: "I4 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 4 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001531 name: lower secondary incisor tooth 4 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i4 anterior-posterior diameter" EXACT [] synonym: "i4 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 4 diamter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001532 name: incisor tooth 4 medial-lateral diameter def: "The diameter at the base of an incisor tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 4 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001533 name: upper secondary incisor tooth 4 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I4 diameter ML" EXACT [] synonym: "I4 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 4 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001534 name: lower secondary incisor tooth 4 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i4 diameter ML" EXACT [] synonym: "i4 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 4 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001535 name: incisor tooth 4 crown height def: "The height of an incisor tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001536 name: upper secondary incisor tooth 4 crown height def: "The height of an upper secondary incisor tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I4 crown height" EXACT [] is_a: FOVT:0001535 ! incisor tooth 4 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001537 name: lower secondary incisor tooth 4 crown height def: "The height of a lower secondary incisor tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i4 crown height" EXACT [] is_a: FOVT:0001535 ! incisor tooth 4 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 4" xsd:string [Term] id: FOVT:0001538 name: incisor tooth 5 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 5 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001539 name: upper secondary incisor tooth 5 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I5 anterior-posterior diameter" EXACT [] synonym: "I5 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 5 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001540 name: lower secondary incisor tooth 5 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i5 anterior-posterior diameter" EXACT [] synonym: "i5 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 5 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001541 name: incisor tooth 5 medial-lateral diameter def: "The diameter at the base of an incisor tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 5 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001542 name: upper secondary incisor tooth 5 medial-lateral diameter def: "The diamter at the base of an upper secondary incisor tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I5 diameter ML" EXACT [] synonym: "I5 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 5 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001543 name: lower secondary incisor tooth 5 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i5 diameter ML" EXACT [] synonym: "i5 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 5 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001544 name: incisor tooth 5 crown height def: "The height of an incisor tooth 5 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001545 name: upper secondary incisor tooth 5 crown height def: "The height of an upper secondary incisor tooth 5 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I5 crown height" EXACT [] is_a: FOVT:0001544 ! incisor tooth 5 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001546 name: lower secondary incisor tooth 5 crown height def: "The height of a lower secondary incisor tooth 5 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i5 crown height" EXACT [] is_a: FOVT:0001544 ! incisor tooth 5 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 5" xsd:string [Term] id: FOVT:0001547 name: incisor tooth 6 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 6 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 6 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001548 name: upper secondary incisor tooth 6 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 6 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I6 anterior-posterior diameter" EXACT [] synonym: "I6 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 6 diamter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001549 name: lower secondary incisor tooth 6 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 6 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i6 anterior-posterior diameter" EXACT [] synonym: "i6 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 6 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001550 name: incisor tooth 6 medial-lateral diameter def: "The diameter at the base of an incisor tooth 6 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 6 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001551 name: upper secondary incisor tooth 6 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 6 along the medial-latearl axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I6 diameter ML" EXACT [] synonym: "I6 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 6 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001552 name: lower secondary incisor tooth 6 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 6 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i6 diameter ML" EXACT [] synonym: "i6 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 6 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add alveolar ridge mandible" xsd:string property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001553 name: incisor tooth 6 crown height def: "The height of an incisor tooth 6 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001554 name: upper secondary incisor 6 tooth crown height def: "The height of an upper secondary incisor tooth 6 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I6 crown height" EXACT [] is_a: FOVT:0001553 ! incisor tooth 6 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:0003499 ! midface morphology is_a: OBA:VT0000452 ! mouth morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001709 ! inheres in upper jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001555 name: lower secondary incisor tooth 6 crown height def: "The height of a lower secondary incisor tooth 6 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i6 crown height" EXACT [] is_a: FOVT:0001553 ! incisor tooth 6 crown height is_a: OBA:0002134 ! dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001710 ! inheres in lower jaw region relationship: RO:0000052 UBERON:0007774 ! inheres in secondary dentition property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add incisor tooth 6" xsd:string [Term] id: FOVT:0001556 name: incisor tooth diameter def: "The diameter of an incisor tooth." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0001334 ! diameter intersection_of: PATO:0001334 ! diameter intersection_of: RO:0000052 UBERON:0001098 ! inheres in incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001557 name: metapodial bone of digit 2 proximal articular breadth def: "The breadth along the medial-lateral axis of the proximal end of a metapodial bone of digit 2." [] synonym: "metapodial II proximal articular breadth" EXACT [] synonym: "Metapodial II proximal breadth (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003646 ! inheres in metacarpal bone of digit 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add logical def" xsd:string [Term] id: FOVT:0001558 name: metacarpal bone of digit 3 medial length def: "The length of the medial side of a metacarpal bone of digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001559 name: metacarpal bone of digit 3 proximal articular depth def: "The depth of the proximal articular surface of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001560 name: metacarpal bone of digit 3 articular facet for the third carpal diameter def: "The diameter of the articular facet of the third carpal of a metacarpal of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal maximal diameter of the articular facet for the third carpal (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add facet" xsd:string [Term] id: FOVT:0001561 name: metacarpal bone of digit 3 anterior facet for the fourth carpal diameter def: "The diameter of the anterior facet for the fourth carpal of a metacarpal bone of digit 3 along the superior-inferior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal diameter of the anterior facet for the fourth carpal (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add facet" xsd:string [Term] id: FOVT:0001562 name: metacarpal bone of digit 3 articular facet for the second carpal diameter def: "The diameter of the articular facet for the second carpal of a metacarpal bone of digit 3 along the superior-inferior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal diameter of the articular facet for the second carpal (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add facet" xsd:string [Term] id: FOVT:0001563 name: metacarpal bone of digit 3 distal supra-articular breadth def: "The breadth of the distal supra-articular of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal maximal supra-articular breadth (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add supra-articular" xsd:string [Term] id: FOVT:0001564 name: metacarpal bone of digit 3 keel depth def: "The depth of the keel of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal maximal depth of the keel (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add keel" xsd:string [Term] id: FOVT:0001565 name: metacarpal bone of digit 3 medial condyle depth def: "The depth of the medial condyle of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal minimal depth of the medial condyle (M14)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add medial condyle" xsd:string [Term] id: FOVT:0001566 name: metacarpal bone of digit 3 posterior facet for the fourth carpal diameter def: "The diameter of the posterior facet for the fourth carpal of a metacarpal bone of digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal diameter of the posterior facet for the fourth carpal (M16)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add facet" xsd:string [Term] id: FOVT:0001567 name: metacarpal bone of digit 2 diaphysis depth def: "The depth of the diaphysis of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002097 ! metacarpal bone diaphysis depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001568 name: metacarpal bone of digit 4 diaphysis depth def: "The depth of the diaphysis of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003648 ! inheres in metacarpal bone of digit 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001569 name: fused metacarpal bones 3 and 4 length def: "The length of a fused metacarpal bones 3 and 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "metacarpal III+IV greatest length (GL)" RELATED [ISBN:9780873659505] is_a: FOVT:0001140 ! fused metatarsal bones 3 and 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001570 name: fused metacarpal bones 3 and 4 diaphysis depth def: "The depth of the diaphysis of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III+IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001571 name: metacarpal bone of digit 2 proximal breadth def: "The breadth of the proximal side of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001572 name: metacarpal bone of digit 4 proximal breadth def: "The breadth of the proximal side of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metacarpal IV proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001573 name: fused metacarpal bones 3 and 4 proximal breadth def: "The breadth of the proximal side of a fused metacarpal bones 3 and 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal III+IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001574 name: metacarpal bone of digit 2 proximal depth def: "The length of the proximal end of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002099 ! metacarpal bone proximal depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001575 name: metacarpal bone of digit 4 proximal depth def: "The length of the proximal end of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002099 ! metacarpal bone proximal depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001576 name: fused metacarpal bones 3 and 4 proximal depth def: "The length of the proximal end of a fused metacarpal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III+IV greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001577 name: metacarpal bone of digit 2 distal articular breadth def: "The breadth of the distal articular surface of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003646 ! inheres in metacarpal bone of digit 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001578 name: metacarpal bone of digit 4 distal articular breadth def: "The breadth of the distal articular surface of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003648 ! inheres in metacarpal bone of digit 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001579 name: metacapral bone of digit 2 distal articular depth def: "The depth of the distal articular of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003646 ! inheres in metacarpal bone of digit 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001580 name: metacapral bone of digit 4 distal articular depth def: "The depth of the distal articular of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003648 ! inheres in metacarpal bone of digit 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001581 name: obsolete metacarpal bone of digit 2 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metacarpal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: measurement not taken synonym: "metacarpal II greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001582 name: obsolete metacarpal bone of digit 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metacarpal bone of digit 4 along the proximal-distal axis." [ISBN:9780873659505] comment: measurement not taken synonym: "metacarpal IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001583 name: obsolete fused metacarpal bones 3 and 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a fused metacarpal bones 3 and 4 from the articular facet for the distal carpal bone 3 and anterior facet for the anterio facet for carpal bone 4 to the lateral condyle." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal III&IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 is_obsolete: true [Term] id: FOVT:0001584 name: fused metacarpal bones 3 and 4 outer lateral length def: "The length of the lateral side of a fused metacarpal bones 3 and 4 from the anterior facet for distal carpal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metacarpal III&IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001585 name: obsolete metacarpal bone of digit 2 outer lateral length def: "OBSOLETE. The length of the lateral side of a metacarpal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metacapral II lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001586 name: obsolete metacarpal bone of digit 4 outer lateral length def: "OBSOLETE. The length of the lateral side of a metacarpal bone of digit 4 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metacapral IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001587 name: obsolete metacarpal bone of digit 2 diaphysis breadth def: "OBSOLETE. The width of the diaphysis of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string is_obsolete: true [Term] id: FOVT:0001588 name: metacarpal bone of digit 4 diaphysis breadth def: "The width of the diaphysis of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal IV breadth in the middle of the diaphysis (B)" RELATED [ISBN:9780873659505] is_a: FOVT:0002102 ! metacarpal bone diaphysis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001589 name: fused metacarpal bones 3 and 4 diaphysis breadth def: "The width of the diaphysis of a fused metacarpal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal III&IV smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001590 name: fused metacarpal bones 3 and 4 diaphysis circumference def: "The circumference of the diaphysis of a fused metacarpal boned 3 and 4." [ISBN:9780873659505] synonym: "metacarpal III&IV smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001648 ! circumference relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001591 name: obsolete metacarpal bone of digit 2 diaphysis circumference def: "OBSOLETE. The circumference of the diaphysis of a metacarpal bone of digit 2." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string is_obsolete: true [Term] id: FOVT:0001592 name: obsolete metacarpal bone of digit 4 diaphysis circumference def: "OBSOLETE. The circumference of the diaphysis of a metacarpal bone of digit 4." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal IV smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string is_obsolete: true [Term] id: FOVT:0001593 name: obsolete metacarpal bone of digit 2 distal breadth def: "OBSOLETE. The width of the distal end of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add distal" xsd:string is_obsolete: true [Term] id: FOVT:0001594 name: metacarpal bone of digit 4 distal breadth def: "The width of the distal end of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 property_value: oboInOwl:editor_note "need to add distal" xsd:string [Term] id: FOVT:0001595 name: fused metacarpal bones 3 and 4 distal breadth def: "The width of the distal end of a fused metacarpal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal III&IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 property_value: oboInOwl:editor_note "need to add distal" xsd:string [Term] id: FOVT:0001596 name: fused metacarpal bones 3 and 4 distal depth def: "The depth of the distal end of a fused metacarpal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III&IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add distal" xsd:string [Term] id: FOVT:0001597 name: metacarpal bone of digit 2 distal depth def: "The depth of the distal end of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003646 ! inheres in metacarpal bone of digit 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add distal" xsd:string [Term] id: FOVT:0001598 name: metacarpal bone of digit 4 distal depth def: "The depth of the distal end of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add distal" xsd:string [Term] id: FOVT:0001599 name: metacarpal bone of digit 3 outer lateral length def: "The length of the lateral side of a metacarpal bone of digit 3 from the anterior facet for distal carpal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metacarpal III lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001600 name: metacarpal bone of digit 3 diaphysis circumference def: "The circumference of the diaphysis of a metacarpal bone of digit 3." [ISBN:9780873659505] synonym: "metacarpal III smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:VT1000361 ! cannon bone circumference relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001601 name: metacarpal bone of digit 3 distal breadth def: "The width of the distal end of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal III greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: oboInOwl:editor_note "need to add distal" xsd:string [Term] id: FOVT:0001602 name: metacarpal bone of digit 3 distal depth def: "The depth of the distal end of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add distal" xsd:string [Term] id: FOVT:0001603 name: metatarsal bone of digit 3 medial length def: "The length on the medial size of a metatarsal bone of digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001604 name: metatarsal bone of digit 3 diaphysis breadth def: "The breadth of the diaphysis of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third metatarsal minimal breadth (near the middle of the bone) (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002106 ! metatarsal bone diaphysis breadth is_a: OBA:1000413 ! metatarsal bone of digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001605 name: metatarsal bone of digit 3 diaphysis depth def: "The depth of the diaphysis of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III minimal depth of the diaphysis (DD)" RELATED [ISBN:9780873659505] synonym: "third metatarsal depth of the diaphysis at the level of M3 (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002105 ! metatarsal bone diaphysis depth is_a: OBA:1000413 ! metatarsal bone of digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001606 name: metatarsal bone of digit 3 proximal articular breadth def: "The breadth of the proximal articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third metatarsal proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001607 name: metatarsal bone of digit 3 proximal articular depth def: "The depth of the articular of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001608 name: metatarsal bone of digit 3 aricular facet for third tarsal diameter def: "The diameter of the articular facet for the third tarsal on a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal maximal diameter of the articular facet for the third tarsal (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001609 name: metatarsal bone of digit 3 aricular facet for fourth tarsal diameter def: "The diameter of the articular facet for fourth tarsal of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal diameter of the articular facet for the fourth tarsal (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001610 name: metatarsal bone of digit 3 aricular facet for second tarsal diameter synonym: "The diameter of the articular facet for second tarsal of a metatarsal bone of digit 3 along the anterior-posterior axis." RELATED [ISBN:9004086161\, 9789004086166] synonym: "third metarsal diameter of the articular facet for the second tarsal (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001334 ! diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001611 name: metatarsal bone of digit 3 supra-articular breadth def: "The breadth of the supra-articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal maximal supra-articular breadth (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add supra-articular" xsd:string [Term] id: FOVT:0001612 name: metatarsal bone of digit 3 distal articular breadth def: "The breadth of the distal articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001613 name: metatarsal bone of digit 3 keel depth def: "The depth of the keel (on the distal end) of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] synonym: "third metatarsal distal maximal depth of the keel (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add keel" xsd:string [Term] id: FOVT:0001614 name: metatarsal bone of digit 3 lateral condyle depth def: "The depth of the lateral condyle of a metatarsal boen of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal minimal dpeth of the lateral condyle (M13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001615 name: metatarsal bone of digit 3 medial condyle depth def: "The depth of the medial condyle of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal maximal depth of the medial condyle (M14)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001616 name: metatarsal bone of digit 2 diaphysis depth def: "The depth of the diaphysis of a metatarsal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002105 ! metatarsal bone diaphysis depth is_a: OBA:1000491 ! metatarsal bone of digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001617 name: metatarsal bone of digit 4 diaphysis depth def: "The depth of the diaphysis of a metatarsal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal IV minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002105 ! metatarsal bone diaphysis depth is_a: OBA:1000611 ! metatarsal bone of digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001618 name: fused metatarsal bones 3 and 4 diaphysis depth def: "The depth of the diaphysis of a fused metatarsal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metatarsal III&IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001619 name: metatarsal bone of digit 4 proximal depth def: "The depth of the proximal end of a metatarsal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal IV proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002108 ! metatarsal bone proximal depth is_a: OBA:1000611 ! metatarsal bone of digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001620 name: metatarsal bone of digit 2 proximal depth def: "The depth of the proximal end of a metatarsal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002108 ! metatarsal bone proximal depth is_a: OBA:1000491 ! metatarsal bone of digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001621 name: fused metatarsal bones 3 and 4 proximal depth def: "The depth of the proximal end of a fused metatarsal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001622 name: metatarsal bone of digit 4 proximal breadth def: "The breadth of the proximal end of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metatarsal IV proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001623 name: metatarsal bone of digit 2 proximal breadth def: "The breadth of the proximal end of a metatarsal bone of digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000491 ! metatarsal bone of digit 2 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001624 name: fused metatarsal bones 3 and 4 proximal breadth def: "The breadth of the proximal end of a fused metatarsal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001625 name: metatarsal bone of digit 4 distal articular breadth def: "The breadth of the distal articular of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003653 ! inheres in metatarsal bone of digit 4 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001626 name: metatarsal bone of digit 2 distal articular breadth def: "The breadth of the distal articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000491 ! metatarsal bone of digit 2 quality is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003651 ! inheres in metatarsal bone of digit 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001627 name: metatarsal bone of digit 4 distal articular depth def: "The depth of the distal articular of a metatarsal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal IV distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003653 ! inheres in metatarsal bone of digit 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001628 name: metatarsal bone of digit 2 distal articular depth def: "The depth of the distal articular of a metatarsal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000491 ! metatarsal bone of digit 2 quality is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003651 ! inheres in metatarsal bone of digit 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0001629 name: obsolete metatarsal bone of digit 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metatarsal bone of digit 4 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001630 name: obsolete metatarsal bone of digit 4 outer lateral length def: "OBSOLETE. The length of the lateral side of a metatarsal bone of digit 4 from the lateral border of articular facet for distal carpal bone 4 to the lateral condyle." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001631 name: obsolete metatarsal bone of digit 2 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metatarsal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001632 name: obsolete metatarsal bone of digit 2 outer lateral length def: "OBSOLETE. The length of the lateral side of a metatarsal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001633 name: obsolete fused metatarsal bones 3 and 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a fused metatarsal bones 3 and 4 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal III&IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001634 name: fused metatarsal bones 3 and 4 outer lateral length def: "The length of the lateral side of a fused metatarsal bones 3 and 4 from the lateral border of articular facet for distal tarsal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metatarsal III&IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001635 name: fused metatarsal bones 3 and 4 diaphysis breadth def: "The breadth of the diaphysis of a fused metatarsal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal III&IV smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001636 name: metatarsal bone of digit 4 diaphysis breadth def: "The breadth of the diaphysis of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal IV breadth in the middle of the diaphysis (B)" RELATED [ISBN:9780873659505] is_a: FOVT:0002106 ! metatarsal bone diaphysis breadth is_a: OBA:1000611 ! metatarsal bone of digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001637 name: obsolete metatarsal bone of digit 2 diaphysis breadth def: "OBSOLETE. The breadth of the diaphysis of a metatarsal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string is_obsolete: true [Term] id: FOVT:0001638 name: metatarsal bone of digit 4 diaphysis circumference def: "The circumference of the diaphysis of a metatarsal bone of digit 4." [ISBN:9780873659505] synonym: "metatarsal IV smallest circumference of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: PATO:0001648 ! circumference relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003653 ! inheres in metatarsal bone of digit 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001639 name: obsolete metatarsal bone of digit 2 diaphysis circumference def: "OBSOLETE. The circumference of the diaphysis of a metatarsal bone of digit 2." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II smallest circumference of the diaphysis (SD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string is_obsolete: true [Term] id: FOVT:0001640 name: fused metatarsal bones 3 and 4 diaphysis circumference def: "The circumference of the diaphysis of a fused metatarsal bones 3 and 4." [ISBN:9780873659505] synonym: "metatarsal III&IV smallest circumference of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001648 ! circumference relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013587 ! inheres in fused metacarpal bones 3 and 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001641 name: metatarsal bone of digit 4 distal breadth def: "The breadth of the distal end of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001642 name: obsolete metatarsal bone of digit 2 distal breadth def: "OBSOLETE. The breadth of the distal end of a metatarsal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001643 name: fused metatarsals 3 and 4 distal depth def: "The depth of the distal end of a fused metatarsal bones 3 and 4 along the anterior-posteriod axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001644 name: obsolete metatarsal bone of digit 4 distal depth def: "OBSOLETE. The depth of the distal end of a metatarsal bone of digit 4 along the anterior-posteriod axis." [ISBN:9780873659505] comment: term not mreasured synonym: "metatarsal IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001645 name: obsolete metatarsal bone of digit 2 distal depth def: "OBSOLETE. The depth of the distal end of a metatarsal bone of digit 2 along the anterior-posteriod axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001646 name: fused metatarsal bones 3 and 4 distal breadth def: "The breadth of the distal end of a fused metatarsal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001648 name: metacarpal bone of digit 3 lateral length def: "The greatest length of the lateral side of a metacarpal bone 3 from the articular facet for the distal carpal bone 3 and anterior facet for the anterio facet for carpal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metacarpal III greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001649 name: metatarsal bone of digit 3 lateral length def: "The greatest length of the lateral side of a metatarsal bone of digit 3 from the articular facet for distal tarsal bone 3 and anterior facet for distal tarsal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metatarsal III greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001650 name: metatarsal bone of digit 3 outer lateral length def: "The length of the lateral side of a metatarsal bone of digit 3 from the lateral border of articular facet for distal tarsal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metatarsal III lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001651 name: metacarpal bone of digit 5 distal breadth def: "The width of the distal end of a metacarpal bone of digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal V greatest breadth of the distal end (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:33554 property_value: measured_in_taxon NCBITaxon:9975 [Term] id: FOVT:0001652 name: metatarsal bone of digit 3 distal breadth def: "The width of the distal end of a metatarsal bone of digit 3 along the medial-lateral axis." [] synonym: "metatarsal III greatest breadth of the distal (Bp)" RELATED [] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001653 name: metatarsal bone of digit 5 distal breadth def: "The width of the distal end of a metatarsal bone of digit 5 along the medial-lateral axis." [] synonym: "metatarsal V greatest breadth of the distal (Bp)" RELATED [] is_a: OBA:1000254 ! metatarsal bone of digit 5 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:33554 property_value: measured_in_taxon NCBITaxon:9975 [Term] id: FOVT:0001654 name: metacarpal bone of digit 3 length excluding plantar projection def: "The length of a metacarpal bone of digit 3 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metacarpal III length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0003044 ! metacarpal bone of digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001655 name: metacarpal bone of digit 4 length excluding plantar projection def: "The length of a metacarpal bone of digit 4 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metacarpal IV length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0003045 ! metacarpal bone of digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001656 name: metatarsal bone of digit 3 length excluding plantar projection def: "The length of a metatarsal bone of digit 3 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metatarsal III length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0002565 ! metatarsal bone of digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001657 name: metatarsal bone of digit 4 length excluding plantar projection def: "The length of a metatarsal bone of digit 4 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metatarsal IV length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0002567 ! metatarsal bone of digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001658 name: atlas breadth def: "The widht of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "atlas greatest breadth over wings (GB)" RELATED [ISBN:9780873659505] synonym: "C1 breadth" EXACT [] synonym: "vertebral bone 1 breadth" EXACT [] is_a: OBA:0004026 ! vertebral bone 1 morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001092 ! inheres in vertebral bone 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001092 ! inheres in vertebral bone 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001659 name: atlas length def: "The length of an atlas along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "atlas greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "C1 length" EXACT [] synonym: "vertebral bone 1 length" EXACT [] is_a: OBA:0002823 ! vertebra size is_a: OBA:0004026 ! vertebral bone 1 morphology is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001092 ! inheres in vertebral bone 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001092 ! inheres in vertebral bone 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001660 name: atlas cranial articular surface breadth def: "The width of the cranial articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "atlas greatest breadth of the Facies articularis cranialis (BFcr)" RELATED [ISBN:9780873659505] synonym: "C1 cranial articular surface breadth" EXACT [] synonym: "vertebral bone 1 cranial articular surface breadth" EXACT [] is_a: FOVT:0001658 ! atlas breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001661 name: atlas caudal articular surface breadth def: "The width of the caudal articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "atlas greatest breadth of the Facies articularis caudalis (BFcd)" RELATED [ISBN:9780873659505] synonym: "C1 caudal articular surface breadth" EXACT [] synonym: "vertebral bone 1 caudal articular surface breadth" EXACT [] is_a: FOVT:0001658 ! atlas breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001662 name: atlas length between cranial and caudal articular surface def: "The length from the cranial articular surface of an atlas to the caudal articular surface of an atlas." [ISBN:9780873659505] synonym: "atlas greatest length from the Facies articularis cranialis to the Facies articularis caudalis (GLF)" RELATED [ISBN:9780873659505] synonym: "C1 length between cranial and caudal articular surface" EXACT [] synonym: "vertebral bone 1 length between cranial and caudal articular surface" EXACT [] is_a: FOVT:0001659 ! atlas length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001663 name: atlas dorsal arch length def: "The length of the arch of atlas along the proximal-distal axis." [ISBN:9780873659505] synonym: "atlas length of the Arcus dorsalis (LAd)" RELATED [ISBN:9780873659505] synonym: "C1 dorsal arch length" EXACT [] synonym: "vertebral bone 1 dorsal arch length" EXACT [] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0004026 ! vertebral bone 1 morphology is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0005814 ! inheres in arch of atlas relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0005814 ! inheres in arch of atlas property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001664 name: atlas height def: "The height of an atlas along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "atlas height (H)" RELATED [ISBN:9780873659505] synonym: "C1 height" EXACT [] synonym: "vertebral bone 1 height" EXACT [] is_a: FOVT:0002132 ! vertebra height is_a: OBA:0004026 ! vertebral bone 1 morphology intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0001092 ! inheres in vertebral bone 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001092 ! inheres in vertebral bone 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001665 name: axis body length def: "The length of the body of an axis along the proximal-distal axis." [ISBN:9780873659505] synonym: "axis greatest length in the region of the corpus including the dens (LCDe)" RELATED [ISBN:9780873659505] synonym: "C2 body length" EXACT [] synonym: "vertebral bone 2 body length" EXACT [] is_a: OBA:0004027 ! vertebral bone 2 morphology is_a: OBA:1000138 ! bone element size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:2001984 ! inheres in centrum 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:2001984 ! inheres in centrum 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001666 name: axis arch length def: "The length of the arch of an axis along the proximal-distal axis." [ISBN:9780873659505] synonym: "axis greatest length of the arch including the Processus articulares caudales (LAPa)" RELATED [ISBN:9780873659505] synonym: "C2 arch length" EXACT [] synonym: "vertebral bone 2 arch length" EXACT [] is_a: OBA:0004027 ! vertebral bone 2 morphology is_a: OBA:1000138 ! bone element size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0000218 ! inheres in vertebral arch of axis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0000218 ! inheres in vertebral arch of axis property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add arch" xsd:string [Term] id: FOVT:0001667 name: axis cranial articular surface breadth def: "The width of the cranial articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth of the Facis articularis cranialis (BFcr)" RELATED [ISBN:9780873659505] synonym: "C2 cranial articular surface breadth" EXACT [] synonym: "vertebral bone 2 cranial articular surface breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001668 name: axis caudal articular process breadth def: "The width of the caudal articular process of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth across the Processus articularis caudales (BPacd)" RELATED [ISBN:9780873659505] synonym: "C2 caudal articular process breadth" EXACT [] synonym: "vertebral bone 2 caudal articular process breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add process" xsd:string [Term] id: FOVT:0001669 name: axis transverse articular process breadth def: "The width of the transverse process of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth across the Processus transversi (BPtr)" RELATED [ISBN:9780873659505] synonym: "C2 transverse articular process breadth" EXACT [] synonym: "vertebral bone 2 transverse articular process breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add process" xsd:string property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001670 name: axis breadth def: "The width of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "C2 breadth" EXACT [] synonym: "smallest breadth of the vertebra (SBV)" RELATED [ISBN:9780873659505] synonym: "vertebral bone 2 breadth" EXACT [] is_a: OBA:0004027 ! vertebral bone 2 morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001093 ! inheres in vertebral bone 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001093 ! inheres in vertebral bone 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001671 name: axis caudal articular surface breadth def: "The width of the caudal articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth of the Facis terminalis caudalis (BFcd)" RELATED [ISBN:9780873659505] synonym: "C2 caudal articular surface breadth" EXACT [] synonym: "vertebral bone 2 caudal articular surface breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string property_value: oboInOwl:editor_note "need to add process" xsd:string [Term] id: FOVT:0001672 name: axis height def: "The height of an axis along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "axis greatest height (H)" RELATED [ISBN:9780873659505] synonym: "C2 height" EXACT [] synonym: "vertebral bone 2 height" EXACT [] is_a: FOVT:0002132 ! vertebra height is_a: OBA:0004027 ! vertebral bone 2 morphology intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0001093 ! inheres in vertebral bone 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001093 ! inheres in vertebral bone 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001673 name: proximal phalanx of manual digit 3 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001674 name: proximal phalanx of manual digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001675 name: obsolete proximal phalanx of manual digit 3 proximal breadth comment: already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001673 [Term] id: FOVT:0001676 name: proximal phalanx of manual digit 3 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001677 name: proximal phalanx of manual digit 3 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001678 name: proximal phalanx of manual digit 3 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001679 name: obsolete proximal phalanx of manual digit 3 distal breadth comment: already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001676 [Term] id: FOVT:0001680 name: proximal phalanx of manual digit 3 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001681 name: proximal phalanx of manual digit 3 distal articular surface depth def: "The depth of the distal articular surface of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit distal articular depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001682 name: proximal phalanx of manual digit 3 trigonum phalangis length def: "The length of the trigonum phalangis of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit minimal length of the trigonum phalangis (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonum phalangis" xsd:string [Term] id: FOVT:0001683 name: proximal phalanx of manual digit 3 medial supratuberosity length def: "The length of the medial surpatuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial supratuberosital length (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add supraturberosity" xsd:string [Term] id: FOVT:0001684 name: proximal phalanx of manual digit 3 lateral supratuberosity length def: "The length of the lateral surpatuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral supratuberosital length (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add supraturberosity" xsd:string [Term] id: FOVT:0001685 name: proximal phalanx of manual digit 3 lateral infratuberosity length def: "The length of the lateral infratuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral infratuberosital length (M13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add infraturberosity" xsd:string [Term] id: FOVT:0001686 name: proximal phalanx of manual digit 3 medial infratuberosity length def: "The length of the medial infratuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial infratuberosital length (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add infraturberosity" xsd:string [Term] id: FOVT:0001687 name: proximal phalanx of manual digit 3 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001688 name: proximal phalanx of pedal digit 3 length def: "The length of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003281 ! proximal phalanx of pes length is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004334 ! inheres in proximal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001689 name: proximal phalanx of pedal digit 3 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001690 name: proximal phalanx of pedal digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001691 name: proximal phalanx of pedal digit 3 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001692 name: proximal phalanx of pedal digit 3 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001693 name: proximal phalanx of pedal digit 3 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001694 name: proximal phalanx of pedal digit 3 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001695 name: proximal phalanx of pedal digit 3 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001696 name: proximal phalanx of pedal digit 3 distal articular surface depth def: "The depth of the distal articular surface of a proximal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit distal articular depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001697 name: proximal phalanx of pedal digit 3 trigonum phalangis length def: "The length of a trigonum phalangis of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit minimal length of the trigonum phalangis (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add trigonum phalangis" xsd:string [Term] id: FOVT:0001698 name: proximal phalanx of pedal digit 3 medial supratuberosity length def: "The length of a medial supratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial supratuberosital length (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular supratuberosity" xsd:string [Term] id: FOVT:0001699 name: proximal phalanx of pedal digit 3 lateral supratuberosity length def: "The length of a lateral supratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral supratuberosital length (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular supratuberosity" xsd:string [Term] id: FOVT:0001700 name: proximal phalanx of pedal digit 3 medial infratuberosity length def: "The length of a medial infratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial infratuberosital length (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular infratuberosity" xsd:string [Term] id: FOVT:0001701 name: proximal phalanx of pedal digit 3 lateral infratuberosity length def: "The length of a lateral infratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral infratuberosital length (M13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular infratuberosity" xsd:string [Term] id: FOVT:0001702 name: middle phalanx of manual digit 3 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001703 name: middle phalanx of manual digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002943 ! middle phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001705 name: middle phalanx of manual digit 3 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001706 name: middle phalanx of manual digit 3 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001707 name: middle phalanx of manual digit 3 anterior length def: "The length of the anterior side of a middle phalanx of manual digit 3 along the middle-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002128 ! phalanx of manus anterior length is_a: OBA:0005188 ! manual digit 1 morphology is_a: OBA:1000382 ! middle phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001714 name: middle phalanx of manual digit 3 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001715 name: middle phalanx of pedal digit 3 length def: "The length of a middle phalanx of pedal digit 3 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003369 ! middle phalanx of pedal digit 3 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004325 ! inheres in middle phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001716 name: middle phalanx of pedal digit 3 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001717 name: middle phalanx of pedal digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003369 ! middle phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001718 name: middle phalanx of pedal digit 3 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001719 name: middle phalanx of pedal digit 3 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001720 name: middle phalanx of pedal digit 3 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001722 name: middle phalanx of pedal digit 3 anterior length def: "The length of the anterior side of a middle phalanx of pedal digit 3 along the middle-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002125 ! phalanx of pes anterior length is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001723 name: distal phalanx of manual digit 3 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001724 name: distal phalanx of manual digit 3 articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of facies articularis (BF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit articular breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9788 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001725 name: distal phalanx of manual digit 3 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001726 name: distal phalanx of manual digit 3 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001727 name: distal phalanx of manual digit 3 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 3 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001728 name: distal phalanx of manual digit 3 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001729 name: distal phalanx of pedal digit 3 length def: "The length of a distal phalanx of pedal digit 3 along the distal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004317 ! inheres in distal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001730 name: distal phalanx of pedal digit 3 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001731 name: distal phalanx of pedal digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001732 name: distal phalanx of pedal digit 3 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001733 name: distal phalanx of pedal digit 3 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001734 name: distal phalanx of pedal digit 3 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001735 name: distal phalanx of pedal digit 3 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 3 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001736 name: middle phalanx of manual digit 5 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001737 name: middle phalanx of manual digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002895 ! middle phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001738 name: middle phalanx of manual digit 5 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001739 name: middle phalanx of manual digit 5 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001741 name: middle phalanx of manual digit 5 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001742 name: middle phalanx of pedal digit 5 length def: "The length of a middle phalanx of pedal digit 5 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003371 ! middle phalanx of pedal digit 5 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004327 ! inheres in middle phalanx of pedal digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001743 name: middle phalanx of pedal digit 5 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001744 name: middle phalanx of pedal digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003371 ! middle phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001745 name: middle phalanx of pedal digit 5 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001746 name: middle phalanx of pedal digit 5 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001747 name: middle phalanx of pedal digit 5 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001748 name: distal phalanx of manual digit 1 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001749 name: distal phalanx of manual digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002990 ! distal phalanx of manual digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001750 name: distal phalanx of manual digit 1 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001751 name: distal phalanx of manual digit 1 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001752 name: distal phalanx of manual digit 1 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 1 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of first digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001753 name: distal phalanx of manual digit 1 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001754 name: distal phalanx of pedal digit 1 length def: "The length of a distal phalanx of pedal digit 1 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003057 ! distal phalanx of pedal digit 1 size is_a: OBA:0003067 ! pedal digit 1 phalanx length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004315 ! inheres in distal phalanx of pedal digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001755 name: distal phalanx of pedal digit 1 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001756 name: distal phalanx of pedal digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003057 ! distal phalanx of pedal digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001757 name: distal phalanx of pedal digit 1 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001758 name: distal phalanx of pedal digit 1 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001759 name: distal phalanx of pedal digit 1 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001760 name: distal phalanx of pedal digit 1 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 1 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of first digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001761 name: middle phalanx of manual digit 2 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001762 name: middle phalanx of manual digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002971 ! middle phalanx of manual digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001763 name: middle phalanx of manual digit 2 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001764 name: middle phalanx of manual digit 2 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001766 name: middle phalanx of manual digit 2 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001767 name: middle phalanx of pedal digit 2 length def: "The length of a middle phalanx of pedal digit 2 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003131 ! middle phalanx of pedal digit 2 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004324 ! inheres in middle phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001768 name: middle phalanx of pedal digit 2 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001769 name: middle phalanx of pedal digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003131 ! middle phalanx of pedal digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001770 name: middle phalanx of pedal digit 2 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001771 name: middle phalanx of pedal digit 2 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001772 name: middle phalanx of pedal digit 2 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001774 name: middle phalanx of manual digit 4 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001775 name: middle phalanx of manual digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002920 ! middle phalanx of manual digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001776 name: middle phalanx of manual digit 4 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001777 name: middle phalanx of manual digit 4 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001780 name: middle phalanx of manual digit 4 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001781 name: middle phalanx of pedal digit 4 length def: "The length of a middle phalanx of pedal digit 4 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003370 ! middle phalanx of pedal digit 4 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004326 ! inheres in middle phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001782 name: middle phalanx of pedal digit 4 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001783 name: middle phalanx of pedal digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003370 ! middle phalanx of pedal digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001784 name: middle phalanx of pedal digit 4 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001785 name: middle phalanx of pedal digit 4 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001786 name: middle phalanx of pedal digit 4 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001788 name: distal phalanx of manual digit 5 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001789 name: distal phalanx of manual digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002909 ! distal phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001790 name: distal phalanx of manual digit 5 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001791 name: distal phalanx of manual digit 5 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001792 name: distal phalanx of manual digit 5 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 5 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fifth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001793 name: distal phalanx of manual digit 5 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001794 name: distal phalanx of pedal digit 5 length def: "The length of a distal phalanx of pedal digit 5 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003368 ! distal phalanx of pedal digit 5 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004319 ! inheres in distal phalanx of pedal digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001795 name: distal phalanx of pedal digit 5 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001796 name: distal phalanx of pedal digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003368 ! distal phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001797 name: distal phalanx of pedal digit 5 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001798 name: distal phalanx of pedal digit 5 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001799 name: distal phalanx of pedal digit 5 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001800 name: distal phalanx of pedal digit 5 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 5 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fifth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001801 name: distal phalanx of manual digit 4 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001802 name: distal phalanx of manual digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002166 ! distal phalanx of manual digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001803 name: distal phalanx of manual digit 4 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001804 name: distal phalanx of manual digit 4 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001805 name: distal phalanx of manual digit 4 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 4 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fourth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001806 name: distal phalanx of manual digit 4 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001807 name: distal phalanx of pedal digit 4 length def: "The length of a distal phalanx of pedal digit 4 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003367 ! distal phalanx of pedal digit 4 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004318 ! inheres in distal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001808 name: distal phalanx of pedal digit 4 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001809 name: distal phalanx of pedal digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002165 ! distal phalanx of pedal digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001810 name: distal phalanx of pedal digit 4 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001811 name: distal phalanx of pedal digit 4 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001812 name: distal phalanx of pedal digit 4 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001813 name: distal phalanx of pedal digit 4 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 4 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fourth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001814 name: distal phalanx of manual digit 2 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001815 name: distal phalanx of manual digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002153 ! distal phalanx of manual digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001816 name: distal phalanx of manual digit 2 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001817 name: distal phalanx of manual digit 2 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001818 name: distal phalanx of manual digit 2 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 2 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of second digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001819 name: distal phalanx of manual digit 2 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001820 name: distal phalanx of pedal digit 2 length def: "The length of a distal phalanx of pedal digit 2 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003135 ! distal phalanx of pedal digit 2 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004316 ! inheres in distal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001821 name: distal phalanx of pedal digit 2 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001822 name: distal phalanx of pedal digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002154 ! distal phalanx of pedal digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001823 name: distal phalanx of pedal digit 2 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001824 name: distal phalanx of pedal digit 2 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001825 name: distal phalanx of pedal digit 2 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001826 name: distal phalanx of pedal digit 2 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 2 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of second digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001827 name: middle phalanx of manual digit 1 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:0005188 ! manual digit 1 morphology is_a: OBA:1000382 ! middle phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001828 name: middle phalanx of manual digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:0005188 ! manual digit 1 morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:4200219 ! inheres in middle phalanx of manual digit 1 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001829 name: middle phalanx of manual digit 1 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001830 name: middle phalanx of manual digit 1 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:0005188 ! manual digit 1 morphology is_a: OBA:1000382 ! middle phalanx of manus quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001831 name: proximal phalanx of manual digit 1 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:0005188 ! manual digit 1 morphology is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001832 name: proximal phalanx of manual digit 1 proximal articular surface breadth def: "The depth of the middle end of a middle phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] def: "The width of the proximal articular surface of a proximal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] synonym: "digit 1 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002986 ! proximal phalanx of manual digit 1 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001833 name: proximal phalanx of manual digit 1 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001834 name: proximal phalanx of manual digit 1 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002986 ! proximal phalanx of manual digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001835 name: proximal phalanx of manual digit 1 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:0005188 ! manual digit 1 morphology is_a: OBA:1000610 ! proximal phalanx of manus quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001836 name: proximal phalanx of manual digit 1 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 1 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:0005188 ! manual digit 1 morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001837 name: proximal phalanx of manual digit 1 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:0005188 ! manual digit 1 morphology is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001838 name: proximal phalanx of pedal digit 1 length def: "The length of a proximal phalanx of pedal digit 1 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003061 ! proximal phalanx of pedal digit 1 size is_a: OBA:0003067 ! pedal digit 1 phalanx length is_a: OBA:0003281 ! proximal phalanx of pes length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004332 ! inheres in proximal phalanx of pedal digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001839 name: proximal phalanx of pedal digit 1 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001840 name: proximal phalanx of pedal digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003061 ! proximal phalanx of pedal digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001841 name: proximal phalanx of pedal digit 1 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001842 name: proximal phalanx of pedal digit 1 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001843 name: proximal phalanx of pedal digit 1 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001844 name: proximal phalanx of pedal digit 1 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003061 ! proximal phalanx of pedal digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001845 name: proximal phalanx of pedal digit 1 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 1 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001847 name: proximal phalanx of manual digit 2 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001848 name: proximal phalanx of manual digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002976 ! proximal phalanx of manual digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001849 name: proximal phalanx of manual digit 2 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001850 name: proximal phalanx of manual digit 2 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002976 ! proximal phalanx of manual digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001851 name: proximal phalanx of manual digit 2 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001853 name: proximal phalanx of manual digit 2 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001854 name: proximal phalanx of manual digit 2 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001855 name: proximal phalanx of pedal digit 2 length def: "The length of a proximal phalanx of pedal digit 2 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003127 ! proximal phalanx of pedal digit 2 size is_a: OBA:0003281 ! proximal phalanx of pes length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004333 ! inheres in proximal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001856 name: proximal phalanx of pedal digit 2 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001857 name: proximal phalanx of pedal digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003127 ! proximal phalanx of pedal digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001858 name: proximal phalanx of pedal digit 2 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001859 name: proximal phalanx of pedal digit 2 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001860 name: proximal phalanx of pedal digit 2 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001861 name: proximal phalanx of pedal digit 2 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003127 ! proximal phalanx of pedal digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001862 name: proximal phalanx of pedal digit 2 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001863 name: proximal phalanx of manual digit 5 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001864 name: proximal phalanx of manual digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002904 ! proximal phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001865 name: proximal phalanx of manual digit 5 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001866 name: proximal phalanx of manual digit 5 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002904 ! proximal phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001867 name: proximal phalanx of manual digit 5 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001868 name: proximal phalanx of manual digit 5 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 5 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001869 name: proximal phalanx of manual digit 5 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001870 name: proximal phalanx of pedal digit 5 length def: "The length of a proximal phalanx of pedal digit 5 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003281 ! proximal phalanx of pes length is_a: OBA:0003374 ! proximal phalanx of pedal digit 5 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004336 ! inheres in proximal phalanx of pedal digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001871 name: proximal phalanx of pedal digit 5 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001872 name: proximal phalanx of pedal digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003374 ! proximal phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001873 name: proximal phalanx of pedal digit 5 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001874 name: proximal phalanx of pedal digit 5 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001875 name: proximal phalanx of pedal digit 5 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001876 name: proximal phalanx of pedal digit 5 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003374 ! proximal phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001877 name: proximal phalanx of pedal digit 5 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 5 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001878 name: proximal phalanx of manual digit 4 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001879 name: proximal phalanx of manual digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002927 ! proximal phalanx of manual digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001880 name: proximal phalanx of manual digit 4 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001881 name: proximal phalanx of manual digit 4 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002927 ! proximal phalanx of manual digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001882 name: proximal phalanx of manual digit 4 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001883 name: proximal phalanx of manual digit 4 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001884 name: proximal phalanx of manual digit 4 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001885 name: proximal phalanx of pedal digit 4 length def: "The length of a proximal phalanx of pedal digit 4 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003281 ! proximal phalanx of pes length is_a: OBA:0003373 ! proximal phalanx of pedal digit 4 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004335 ! inheres in proximal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001886 name: proximal phalanx of pedal digit 4 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001887 name: proximal phalanx of pedal digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003373 ! proximal phalanx of pedal digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001888 name: proximal phalanx of pedal digit 4 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001889 name: proximal phalanx of pedal digit 4 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0001890 name: proximal phalanx of pedal digit 4 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001891 name: proximal phalanx of pedal digit 4 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003373 ! proximal phalanx of pedal digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001892 name: proximal phalanx of pedal digit 4 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001893 name: sacrum length def: "The length on the ventral side of a fused sacrum along the proximal-distal axis." [ISBN:9780873659505] comment: This is measured from the cranial borders of the wings to the centroventral border of the body of the last vertebra. {xref="ISBN:9780873659505"} synonym: "fused sacrum length" EXACT [] synonym: "sacrum greatest length of the ventral side (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002556 ! fused sacrum size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003690 ! inheres in fused sacrum relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001894 name: sacrum physiological length def: "The length of the body of a fused sacrum on the ventral side along the proximal-distal axis." [ISBN:9780873659505] comment: This is measured between the centers of the bodies of the most cranial and most caudal vertebrae. {xref="ISBN:9780873659505"} synonym: "fused sacrum physiological length" EXACT [] synonym: "sacrum physiological length (PL)" RELATED [ISBN:9780873659505] is_a: FOVT:0001893 ! sacrum length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001895 name: sacrum breadth def: "The width of a fused sacrum along the medial-lateral axis." [ISBN:9780873659505] synonym: "fused sacrum breadth" EXACT [] synonym: "sacrum greatest breadth across the wings (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0002556 ! fused sacrum size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0003690 ! inheres in fused sacrum relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001896 name: sacrum cranial articular surface breadth def: "The width of the cranial articular surface of a fused sacrum along the medial-lateral axis." [ISBN:9780873659505] synonym: "fused sacrum cranial articular surface breadth" EXACT [] synonym: "sacrum greatest breadth of the facies terminalis cranialis (BFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001895 ! sacrum breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001897 name: sacrum cranial articular surface height def: "The height of the cranial articular surface of a fused sacrum along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "fused sacrum cranial articular surface height" EXACT [] synonym: "sacrum greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: OBA:0002556 ! fused sacrum size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001898 name: thoracic vertebra physiological length def: "The length of the body of a thoracic vertebra along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0002347 ! inheres in thoracic vertebra property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001899 name: thoracic vertebra transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0002347 ! inheres in thoracic vertebra property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001900 name: thoracic vertebra cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0002347 ! inheres in thoracic vertebra property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001901 name: thoracic vertebra caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0002347 ! inheres in thoracic vertebra property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001902 name: thoracic vertebra cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001903 name: thoracic vertebra caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001904 name: thoracic vertebra height def: "The height of a thoracic vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height is_a: OBA:VT0003047 ! thoracic vertebra morphology trait intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0002347 ! inheres in thoracic vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0002347 ! inheres in thoracic vertebra property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001905 name: cervical vertebra physiological length def: "The length of the body of a cervical vertebra along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "cervical vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001906 name: cervical vertebra length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0001907 name: cervical vertebra cranial articular process breadth def: "The width of the cranial articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0001908 name: cervical vertebra caudal articular process breadth def: "The width of the caudal articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0001909 name: cervical vertebra transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002134 ! vertebra transverse process breadth intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018143 ! inheres in transverse process of cervical vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018143 ! inheres in transverse process of cervical vertebra property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001910 name: cervical vertebra cranial articular surface height def: "The hieght of the cranial articular surface of a cervical vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001911 name: cervical vertebra caudal articular surface height def: "The hieght of the caudal articular surface of a cervical vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001912 name: cervical vertebra height def: "The height of a cervical vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height is_a: OBA:0002830 ! cervical vertebra size intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0002413 ! inheres in cervical vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001913 name: lumbar vertebra physiological length def: "The length of the body of a lumbar vertebra along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001914 name: lumbar vertebra transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002134 ! vertebra transverse process breadth is_a: OBA:VT0010494 ! lumbar vertebra morphology trait intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0018146 ! inheres in transverse process of lumbar vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0018146 ! inheres in transverse process of lumbar vertebra property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001915 name: lumbar vertebra cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001916 name: lumbar vertebra caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001917 name: lumbar vertebra height def: "The height of a lumbar vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height is_a: OBA:VT0010518 ! lumbar vertebra size trait intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0002414 ! inheres in lumbar vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001918 name: thoracic vertebra 1 physiological length def: "The length of the body of a thoracic vertebra 1 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 1 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004626 ! inheres in thoracic vertebra 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001919 name: thoracic vertebra 1 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004626 ! inheres in thoracic vertebra 1 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001920 name: thoracic vertebra 1 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004626 ! inheres in thoracic vertebra 1 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001921 name: thoracic vertebra 1 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004626 ! inheres in thoracic vertebra 1 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001922 name: thoracic vertebra 1 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001924 ! thoracic vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001923 name: thoracic vertebra 1 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001924 ! thoracic vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001924 name: thoracic vertebra 1 height def: "The height of a thoracic vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004626 ! inheres in thoracic vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004626 ! inheres in thoracic vertebra 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001925 name: thoracic vertebra 2 physiological length def: "The length of the body of a thoracic vertebra 2 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 2 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004627 ! inheres in thoracic vertebra 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001926 name: thoracic vertebra 2 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004627 ! inheres in thoracic vertebra 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001927 name: thoracic vertebra 2 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004627 ! inheres in thoracic vertebra 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001928 name: thoracic vertebra 2 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004627 ! inheres in thoracic vertebra 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001929 name: thoracic vertebra 2 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001931 ! thoracic vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001930 name: thoracic vertebra 2 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001931 ! thoracic vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001931 name: thoracic vertebra 2 height def: "The height of a thoracic vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004627 ! inheres in thoracic vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004627 ! inheres in thoracic vertebra 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001932 name: thoracic vertebra 3 physiological length def: "The length of the body of a thoracic vertebra 3 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 3 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004628 ! inheres in thoracic vertebra 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001933 name: thoracic vertebra 3 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004628 ! inheres in thoracic vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001934 name: thoracic vertebra 3 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004628 ! inheres in thoracic vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001935 name: thoracic vertebra 3 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004628 ! inheres in thoracic vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001936 name: thoracic vertebra 3 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001938 ! thoracic vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001937 name: thoracic vertebra 3 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001938 ! thoracic vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001938 name: thoracic vertebra 3 height def: "The height of a thoracic vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004628 ! inheres in thoracic vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004628 ! inheres in thoracic vertebra 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001939 name: thoracic vertebra 5 physiological length def: "The length of the body of a thoracic vertebra 5 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 5 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004630 ! inheres in thoracic vertebra 5 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001940 name: thoracic vertebra 5 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004630 ! inheres in thoracic vertebra 5 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001941 name: thoracic vertebra 5 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004630 ! inheres in thoracic vertebra 5 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001942 name: thoracic vertebra 5 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004630 ! inheres in thoracic vertebra 5 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001943 name: thoracic vertebra 5 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001945 ! thoracic vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001944 name: thoracic vertebra 5 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001945 ! thoracic vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001945 name: thoracic vertebra 5 height def: "The height of a thoracic vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004630 ! inheres in thoracic vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004630 ! inheres in thoracic vertebra 5 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001946 name: thoracic vertebra 4 physiological length def: "The length of the body of a thoracic vertebra 4 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 4 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004629 ! inheres in thoracic vertebra 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001947 name: thoracic vertebra 4 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004629 ! inheres in thoracic vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001948 name: thoracic vertebra 4 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004629 ! inheres in thoracic vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001949 name: thoracic vertebra 4 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004629 ! inheres in thoracic vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001950 name: thoracic vertebra 4 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001952 ! thoracic vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001951 name: thoracic vertebra 4 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001952 ! thoracic vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001952 name: thoracic vertebra 4 height def: "The height of a thoracic vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004629 ! inheres in thoracic vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004629 ! inheres in thoracic vertebra 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001953 name: thoracic vertebra 6 physiological length def: "The length of the body of a thoracic vertebra 6 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 6 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004631 ! inheres in thoracic vertebra 6 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001954 name: thoracic vertebra 6 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004631 ! inheres in thoracic vertebra 6 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001955 name: thoracic vertebra 6 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004631 ! inheres in thoracic vertebra 6 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001956 name: thoracic vertebra 6 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004631 ! inheres in thoracic vertebra 6 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001957 name: thoracic vertebra 6 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001959 ! thoracic vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001958 name: thoracic vertebra 6 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001959 ! thoracic vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001959 name: thoracic vertebra 6 height def: "The height of a thoracic vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004631 ! inheres in thoracic vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004631 ! inheres in thoracic vertebra 6 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001960 name: thoracic vertebra 12 physiological length def: "The length of the body of a thoracic vertebra 12 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 12 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004636 ! inheres in thoracic vertebra 12 [Term] id: FOVT:0001961 name: thoracic vertebra 12 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004636 ! inheres in thoracic vertebra 12 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001962 name: thoracic vertebra 12 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 12 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004636 ! inheres in thoracic vertebra 12 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001963 name: thoracic vertebra 12 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 12 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004636 ! inheres in thoracic vertebra 12 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001964 name: thoracic vertebra 12 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 12 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001966 ! thoracic vertebra 12 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001965 name: thoracic vertebra 12 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 12 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001966 ! thoracic vertebra 12 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001966 name: thoracic vertebra 12 height def: "The height of a thoracic vertebra 12 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004636 ! inheres in thoracic vertebra 12 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004636 ! inheres in thoracic vertebra 12 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001967 name: thoracic vertebra 7 physiological length def: "The length of the body of a thoracic vertebra 7 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 7 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004632 ! inheres in thoracic vertebra 7 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001968 name: thoracic vertebra 7 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004632 ! inheres in thoracic vertebra 7 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001969 name: thoracic vertebra 7 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004632 ! inheres in thoracic vertebra 7 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001970 name: thoracic vertebra 7 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004632 ! inheres in thoracic vertebra 7 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001971 name: thoracic vertebra 7 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001973 ! thoracic vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001972 name: thoracic vertebra 7 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001973 ! thoracic vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001973 name: thoracic vertebra 7 height def: "The height of a thoracic vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004632 ! inheres in thoracic vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004632 ! inheres in thoracic vertebra 7 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001974 name: thoracic vertebra 11 physiological length def: "The length of the body of a thoracic vertebra 11 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 11 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004635 ! inheres in thoracic vertebra 11 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001975 name: thoracic vertebra 11 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004635 ! inheres in thoracic vertebra 11 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001976 name: thoracic vertebra 11 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 11 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004635 ! inheres in thoracic vertebra 11 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001977 name: thoracic vertebra 11 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 11 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004635 ! inheres in thoracic vertebra 11 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001978 name: thoracic vertebra 11 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 11 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001980 ! thoracic vertebra 11 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001979 name: thoracic vertebra 11 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 11 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001980 ! thoracic vertebra 11 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001980 name: thoracic vertebra 11 height def: "The height of a thoracic vertebra 11 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004635 ! inheres in thoracic vertebra 11 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004635 ! inheres in thoracic vertebra 11 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001981 name: thoracic vertebra 8 physiological length def: "The length of the body of a thoracic vertebra 8 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 8 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0011050 ! inheres in thoracic vertebra 8 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001982 name: thoracic vertebra 8 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0011050 ! inheres in thoracic vertebra 8 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001983 name: thoracic vertebra 8 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 8 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0011050 ! inheres in thoracic vertebra 8 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001984 name: thoracic vertebra 8 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 8 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0011050 ! inheres in thoracic vertebra 8 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001985 name: thoracic vertebra 8 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 8 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001987 ! thoracic vertebra 8 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001986 name: thoracic vertebra 8 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 8 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001987 ! thoracic vertebra 8 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001987 name: thoracic vertebra 8 height def: "The height of a thoracic vertebra 8 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0011050 ! inheres in thoracic vertebra 8 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0011050 ! inheres in thoracic vertebra 8 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001988 name: thoracic vertebra 9 physiological length def: "The length of the body of a thoracic vertebra 9 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 9 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004633 ! inheres in thoracic vertebra 9 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001989 name: thoracic vertebra 9 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004633 ! inheres in thoracic vertebra 9 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001990 name: thoracic vertebra 9 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 9 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004633 ! inheres in thoracic vertebra 9 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001991 name: thoracic vertebra 9 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 9 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004633 ! inheres in thoracic vertebra 9 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001992 name: thoracic vertebra 9 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 9 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001994 ! thoracic vertebra 9 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001993 name: thoracic vertebra 9 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 9 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001994 ! thoracic vertebra 9 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001994 name: thoracic vertebra 9 height def: "The height of a thoracic vertebra 9 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004633 ! inheres in thoracic vertebra 9 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004633 ! inheres in thoracic vertebra 9 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001995 name: thoracic vertebra 10 physiological length def: "The length of the body of a thoracic vertebra 10 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 10 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004634 ! inheres in thoracic vertebra 10 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001996 name: thoracic vertebra 10 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004634 ! inheres in thoracic vertebra 10 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0001997 name: thoracic vertebra 10 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 10 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004634 ! inheres in thoracic vertebra 10 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001998 name: thoracic vertebra 10 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 10 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004634 ! inheres in thoracic vertebra 10 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0001999 name: thoracic vertebra 10 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 10 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002001 ! thoracic vertebra 10 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002000 name: thoracic vertebra 10 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 10 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002001 ! thoracic vertebra 10 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002001 name: thoracic vertebra 10 height def: "The height of a thoracic vertebra 10 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004634 ! inheres in thoracic vertebra 10 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004634 ! inheres in thoracic vertebra 10 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002002 name: lumbar vertebra 1 physiological length def: "The length of the body of a lumbar vertebra 1 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 1 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002003 name: lumbar vertebra 1 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004617 ! inheres in lumbar vertebra 1 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002004 name: lumbar vertebra 1 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 1 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002006 ! lumbar vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002005 name: lumbar vertebra 1 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 1 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002006 ! lumbar vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002006 name: lumbar vertebra 1 height def: "The height of a lumbar vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004617 ! inheres in lumbar vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004617 ! inheres in lumbar vertebra 1 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002007 name: lumbar vertebra 3 physiological length def: "The length of the body of a lumbar vertebra 3 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 3 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002008 name: lumbar vertebra 3 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004619 ! inheres in lumbar vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002009 name: lumbar vertebra 3 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 3 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002011 ! lumbar vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002010 name: lumbar vertebra 3 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 3 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002011 ! lumbar vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002011 name: lumbar vertebra 3 height def: "The height of a lumbar vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004619 ! inheres in lumbar vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004619 ! inheres in lumbar vertebra 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002012 name: lumbar vertebra 4 physiological length def: "The length of the body of a lumbar vertebra 4 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 4 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002013 name: lumbar vertebra 4 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004620 ! inheres in lumbar vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002014 name: lumbar vertebra 4 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 4 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002016 ! lumbar vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002015 name: lumbar vertebra 4 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 4 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002016 ! lumbar vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002016 name: lumbar vertebra 4 height def: "The height of a lumbar vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004620 ! inheres in lumbar vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004620 ! inheres in lumbar vertebra 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002017 name: lumbar vertebra 5 physiological length def: "The length of the body of a lumbar vertebra 5 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 5 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002018 name: lumbar vertebra 5 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:0002828 ! lumbar vertebra 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002019 name: lumbar vertebra 5 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 5 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002021 ! lumbar vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002020 name: lumbar vertebra 5 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 5 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002021 ! lumbar vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002021 name: lumbar vertebra 5 height def: "The height of a lumbar vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height is_a: OBA:0002828 ! lumbar vertebra 5 size intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004621 ! inheres in lumbar vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002022 name: mammalian cervical vertebra 3 physiological length def: "The length of the body of a mammalian cervical vertebra 3 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 3 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004612 ! inheres in mammalian cervical vertebra 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002023 name: mammalian cervical vertebra 3 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004612 ! inheres in mammalian cervical vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002024 name: mammalian cervical vertebra 3 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004612 ! inheres in mammalian cervical vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002025 name: mammalian cervical vertebra 3 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004612 ! inheres in mammalian cervical vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002026 name: mammalian cervical vertebra 3 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004612 ! inheres in mammalian cervical vertebra 3 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002027 name: mammalian cervical vertebra 3 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002029 ! mammalian cervical vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002028 name: mammalian cervical vertebra 3 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002029 ! mammalian cervical vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002029 name: mammalian cervical vertebra 3 height def: "The height of a mammalian cervical vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004612 ! inheres in mammalian cervical vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004612 ! inheres in mammalian cervical vertebra 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002030 name: mammalian cervical vertebra 4 physiological length def: "The length of the body of a mammalian cervical vertebra 4 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 4 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004613 ! inheres in mammalian cervical vertebra 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002031 name: mammalian cervical vertebra 4 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004613 ! inheres in mammalian cervical vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002032 name: mammalian cervical vertebra 4 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004613 ! inheres in mammalian cervical vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002033 name: mammalian cervical vertebra 4 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004613 ! inheres in mammalian cervical vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002034 name: mammalian cervical vertebra 4 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004613 ! inheres in mammalian cervical vertebra 4 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002035 name: mammalian cervical vertebra 4 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002037 ! mammalian cervical vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002036 name: mammalian cervical vertebra 4 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002037 ! mammalian cervical vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002037 name: mammalian cervical vertebra 4 height def: "The height of a mammalian cervical vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004613 ! inheres in mammalian cervical vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004613 ! inheres in mammalian cervical vertebra 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002038 name: mammalian cervical vertebra 5 physiological length def: "The length of the body of a mammalian cervical vertebra 5 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 5 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004614 ! inheres in mammalian cervical vertebra 5 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002039 name: mammalian cervical vertebra 5 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004614 ! inheres in mammalian cervical vertebra 5 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002040 name: mammalian cervical vertebra 5 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004614 ! inheres in mammalian cervical vertebra 5 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002041 name: mammalian cervical vertebra 5 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004614 ! inheres in mammalian cervical vertebra 5 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002042 name: mammalian cervical vertebra 5 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004614 ! inheres in mammalian cervical vertebra 5 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002043 name: mammalian cervical vertebra 5 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002045 ! mammalian cervical vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002044 name: mammalian cervical vertebra 5 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002045 ! mammalian cervical vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002045 name: mammalian cervical vertebra 5 height def: "The height of a mammalian cervical vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004614 ! inheres in mammalian cervical vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004614 ! inheres in mammalian cervical vertebra 5 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002046 name: mammalian cervical vertebra 6 physiological length def: "The length of the body of a mammalian cervical vertebra 6 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 6 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004615 ! inheres in mammalian cervical vertebra 6 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002047 name: mammalian cervical vertebra 6 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004615 ! inheres in mammalian cervical vertebra 6 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002048 name: mammalian cervical vertebra 6 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004615 ! inheres in mammalian cervical vertebra 6 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002049 name: mammalian cervical vertebra 6 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004615 ! inheres in mammalian cervical vertebra 6 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002050 name: mammalian cervical vertebra 6 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004615 ! inheres in mammalian cervical vertebra 6 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002051 name: mammalian cervical vertebra 6 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002053 ! mammalian cervical vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002052 name: mammalian cervical vertebra 6 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002053 ! mammalian cervical vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002053 name: mammalian cervical vertebra 6 height def: "The height of a mammalian cervical vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004615 ! inheres in mammalian cervical vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004615 ! inheres in mammalian cervical vertebra 6 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002054 name: mammalian cervical vertebra 7 physiological length def: "The length of the body of a mammalian cervical vertebra 7 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 7 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004616 ! inheres in mammalian cervical vertebra 7 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002055 name: mammalian cervical vertebra 7 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004616 ! inheres in mammalian cervical vertebra 7 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002056 name: mammalian cervical vertebra 7 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004616 ! inheres in mammalian cervical vertebra 7 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002057 name: mammalian cervical vertebra 7 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004616 ! inheres in mammalian cervical vertebra 7 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular process" xsd:string [Term] id: FOVT:0002058 name: mammalian cervical vertebra 7 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004616 ! inheres in mammalian cervical vertebra 7 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002059 name: mammalian cervical vertebra 7 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002061 ! mammalian cervical vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002060 name: mammalian cervical vertebra 7 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002061 ! mammalian cervical vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002061 name: mammalian cervical vertebra 7 height def: "The height of a mammalian cervical vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004616 ! inheres in mammalian cervical vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004616 ! inheres in mammalian cervical vertebra 7 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002062 name: lumbar vertebra 2 physiological length def: "The length of the body of a lumbar vertebra 2 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 2 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002063 name: lumbar vertebra 2 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004618 ! inheres in lumbar vertebra 2 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002064 name: lumbar vertebra 2 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 2 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002066 ! lumbar vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002065 name: lumbar vertebra 2 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 2 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002066 ! lumbar vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002066 name: lumbar vertebra 2 height def: "The height of a lumbar vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004618 ! inheres in lumbar vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0004618 ! inheres in lumbar vertebra 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002067 name: distal phalanx of manual digit 3 articular surface depth def: "The depth of the articular surface on the proximal end of a distal phalax of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 length of the facies articularis (LF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9788 property_value: oboInOwl:editor_note "need to add articular surface" xsd:string [Term] id: FOVT:0002068 name: distal phalanx of manual digit 3 height def: "The height of a distal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 height in the region of the extensor process (HP)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit maximal height (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004312 ! inheres in distal phalanx of manual digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9788 [Term] id: FOVT:0002069 name: distal phalanx of pes anterior length def: "The length of the anterior side of a distal phalanx of pes along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "third phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000628 ! distal phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002070 name: distal phalanx of pes diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third phalanx minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000628 ! distal phalanx of pes quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010105 ! hindlimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0002071 name: distal phalanx of pes distal breadth def: "The width of the distal end of a distal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "third phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002124 ! phalanx of pes distal breadth is_a: OBA:1000628 ! distal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002072 name: distal phalanx of pes proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pes along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003079 ! distal phalanx of pes size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002073 name: distal phalanx of pes proximal breadth def: "The width of the proximal end of a distal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000628 ! distal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002074 name: distal phalanx of pes proximal depth def: "The depth of the proximal end of a distal phalanx of pes along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000628 ! distal phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002075 name: distal phalanx of manus anterior length def: "The length of the anterior side of a distal phalanx of manus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "third phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002128 ! phalanx of manus anterior length is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002076 name: distal phalanx of manus diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third phalanx minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000190 ! distal phalanx of manus quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add diaphysis" xsd:string [Term] id: FOVT:0002077 name: distal phalanx of manus distal breadth def: "The width of the distal end of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "third phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002129 ! phalanx of manus distal breadth is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002078 name: distal phalanx of manus proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manus along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003006 ! distal phalanx of manus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002079 name: distal phalanx of manus proximal breadth def: "The width of the proximal end of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002080 name: distal phalanx of manus proximal depth def: "The depth of the proximal end of a distal phalanx of manus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002081 name: distal phalanx of manus articular surface breadth def: "The width of the articular surface of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 breadth of the facies articularis (BF)" RELATED [ISBN:9780873659505] synonym: "third phalanx articular breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003006 ! distal phalanx of manus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002082 name: distal phalanx of manus articular surface depth def: "The depth of the articular surface of a distal phalanx of manus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 length of the facies articularis (LF)" RELATED [ISBN:9780873659505] synonym: "third phalanx articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003006 ! distal phalanx of manus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002083 name: middle phalanx of manus distal breadth def: "The width of the distal end of a middle phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "second phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002129 ! phalanx of manus distal breadth is_a: OBA:1000382 ! middle phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002084 name: middle phalanx of pes distal breadth def: "The width of the distal end of a middle phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "second phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002124 ! phalanx of pes distal breadth is_a: OBA:1000492 ! middle phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002085 name: proximal phalanx of manus distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003012 ! proximal phalanx of manus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002086 name: proximal phalanx of manus distal breadth def: "The width of the distal end of a proximal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002129 ! phalanx of manus distal breadth is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002087 name: proximal phalanx of pes distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002088 name: proximal phalanx of pes distal breadth def: "The width of the distal end of a proximal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002124 ! phalanx of pes distal breadth is_a: OBA:1000212 ! proximal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002089 name: obsolete mammalian cervical vertebra physiological length def: "OBSOLETE. The length of the body of a cervical vertebra along the proximal-distal axis." [ISBN:9780873659505] comment: already exists comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "cervical physiological length of the body (PL)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001905 [Term] id: FOVT:0002090 name: obsolete mammalian cervical vertebra length between cranial and caudal articular processes comment: term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001906 [Term] id: FOVT:0002091 name: obsolete mammalian cervical vertebra cranial articular process breadth def: "OBSOLETE. The width of the cranial articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001907 [Term] id: FOVT:0002092 name: obsolete mammalian cervical vertebra caudal articular process breadth def: "OBSOLETE. The width of the caudal articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001908 [Term] id: FOVT:0002093 name: obsolete mammalian cervical vertebra cranial articular surface height def: "OBSOLETE. The height of the cranial articular surface of a cervical vertebra along the dorsal-ventral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest height of the processus terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001910 [Term] id: FOVT:0002094 name: obsolete mammalian cervical vertebra caudal articular surface height def: "OBSOLETE. The height of the caudal articular surface of a cervical vertebra along the dorsal-ventral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest height of the processus terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001911 [Term] id: FOVT:0002095 name: obsolete mammalian cervical vertebra height def: "OBSOLETE. The height of a cervical vertebra along the dorsal-ventral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest height (H)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001912 [Term] id: FOVT:0002096 name: obsolete mammalian cervical vertebra transverse process breadth def: "OBSOLETE. The width between the left and right transverse processes of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string is_obsolete: true replaced_by: FOVT:0001909 [Term] id: FOVT:0002097 name: metacarpal bone diaphysis depth def: "The depth of the diaphysis of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metacarpal smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0013752 ! inheres in diaphysis of metacarpal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013752 ! inheres in diaphysis of metacarpal bone property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002098 name: metacarpal bone proximal breadth def: "The width of the proximal end of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metacarpal proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002116 ! metapodial bone proximal breadth is_a: OBA:0003763 ! metacarpal bone morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002099 name: metacarpal bone proximal depth def: "The depth of the proximal end of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "metacarpal proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002115 ! metapodial bone proximal depth is_a: OBA:0003763 ! metacarpal bone morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002100 name: metacarpal bone distal articular breadth def: "The width of the distal articular of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002101 name: metacarpal bone distal articular depth def: "The depth of the distal articular of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002102 name: metacarpal bone diaphysis breadth def: "The width of the diaphysis of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal minimal breadth (near the middle of the bone) (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metacarpal smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0013752 ! inheres in diaphysis of metacarpal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013752 ! inheres in diaphysis of metacarpal bone property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002103 name: metacarpal bone proximal articular breadth def: "The width of the proximal articular of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metacarpal proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002104 name: metacarpal bone proximal articular depth def: "The depth of the proximal articular of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002105 name: metatarsal bone diaphysis depth def: "The depth of the diaphysis of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0013774 ! inheres in diaphysis of metatarsal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013774 ! inheres in diaphysis of metatarsal bone property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002106 name: metatarsal bone diaphysis breadth def: "The width of the diaphysis of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal minimal breadth (near the middle of the bone) (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0013774 ! inheres in diaphysis of metatarsal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0013774 ! inheres in diaphysis of metatarsal bone property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002107 name: metatarsal bone proximal breadth def: "The width of the proximal end of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metatarsal proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002116 ! metapodial bone proximal breadth is_a: OBA:VT0003072 ! metatarsus morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002108 name: metatarsal bone proximal depth def: "The depth of the proximal end of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002115 ! metapodial bone proximal depth is_a: OBA:VT0003072 ! metatarsus morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002109 name: metatarsal bone distal articular breadth def: "The width of the distal articular of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002110 name: metatarsal bone distal articular depth def: "The depth of the distal articular of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002111 name: metatarsal bone proximal articular breadth def: "The width of the proximal articular of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metatarsal proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002112 name: metatarsal bone proximal articular depth def: "The depth of the proximal articular of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002113 name: metapodial bone proximal articular depth def: "The depth of the proximal articular of a metapodial bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metapodial proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002651 ! long bone size is_a: OBA:0005468 ! limb long bone morphology is_a: OBA:VT0000572 ! autopod morphology trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003821 ! inheres in metapodium bone property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002114 name: metapodial bone proximal articular breadth def: "The width of the proximal articular of a metapodial bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metapodial greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metapodial proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002651 ! long bone size is_a: OBA:0005468 ! limb long bone morphology is_a: OBA:VT0000572 ! autopod morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003821 ! inheres in metapodium bone property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002115 name: metapodial bone proximal depth def: "The depth of the proximal end of a metapodial bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metapodial greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: OBA:0005468 ! limb long bone morphology is_a: OBA:VT0000572 ! autopod morphology trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002116 name: metapodial bone proximal breadth def: "The width of the proximal end of a metapodial bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metapodial greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metapodial proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0005468 ! limb long bone morphology is_a: OBA:VT0000572 ! autopod morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002117 name: metapodial bone distal articular breadth def: "The width of the distal articular of a metapodial bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metapodial distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002651 ! long bone size is_a: OBA:0005468 ! limb long bone morphology is_a: OBA:VT0000572 ! autopod morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003821 ! inheres in metapodium bone property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002118 name: metapodial bone distal articular depth def: "The depth of the distal articular of a metapodial bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metapodial distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002651 ! long bone size is_a: OBA:0005468 ! limb long bone morphology is_a: OBA:VT0000572 ! autopod morphology trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003821 ! inheres in metapodium bone property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add articular" xsd:string [Term] id: FOVT:0002119 name: phalanx distal breadth def: "The width of the distal end of a phalanx along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002120 name: obsolete phalanx distal distal articular breadth comment: not needed relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0002121 name: phalanx anterior length def: "The length of the anterior side of a phalanx along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002122 name: phalanx proximal breadth def: "The width of the proximal end of a phalanx along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002123 name: phalanx proximal depth def: "The depth of the proximal end of a phalanx along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002124 name: phalanx of pes distal breadth def: "The width of the distal end of a phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002119 ! phalanx distal breadth is_a: OBA:1000501 ! phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002125 name: phalanx of pes anterior length def: "The length of the anterior side of a phalanx of pes along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000492 ! middle phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002126 name: phalanx of pes proximal breadth def: "The width of the proximal end of a phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002122 ! phalanx proximal breadth is_a: OBA:1000501 ! phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002127 name: phalanx of pes proximal depth def: "The depth of the proximal end of a phalanx of pes along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000492 ! middle phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002128 name: phalanx of manus anterior length def: "The length of the anterior side of a phalanx of manus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0010104 ! forelimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002129 name: phalanx of manus distal breadth def: "The width of the distal end of a phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002119 ! phalanx distal breadth is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0010104 ! forelimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002130 name: phalanx of manus proximal breadth def: "The width of the proximal end of a phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002122 ! phalanx proximal breadth is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0010104 ! forelimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002131 name: phalanx of manus proximal depth def: "The depth of the proximal end of a phalanx of manus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0010104 ! forelimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002132 name: vertebra height def: "The height of a vertebra along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0002412 ! inheres in vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002133 name: vertebra physiological length def: "The length of a vertebra body along the proximal-distal axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002134 name: vertebra transverse process breadth def: "The width between the left and right transverse processes of a vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:1000675 ! transverse process of vertebra quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001077 ! inheres in transverse process of vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001077 ! inheres in transverse process of vertebra property_value: IAO:0000114 IAO:0000423 property_value: oboInOwl:editor_note "need to add transverse process" xsd:string [Term] id: FOVT:0002135 name: vertebra cranial articular surface height def: "The height of the cranial articular surface of a vertebra along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "vertebra greatest height of the processus terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002136 name: vertebra caudal articular surface height def: "The height of the caudal articular surface of a vertebra along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "vertebra greatest height of the processus terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002137 name: proximal phalanx of manus anterior length def: "The length of the anterior side of a phalanx of manus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002128 ! phalanx of manus anterior length is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002138 name: proximal phalanx of pes anterior length def: "The length of the anterior side of a phalanx of pes along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002139 name: metatarsal bone of digit 3 diaphysis circumference def: "The circumference of the diaphysis of a metatarsal bone of digit 3." [ISBN:9780873659505] synonym: "metatarsal III smallest circumference of hte diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001648 ! circumference relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002140 name: metacarpal bone of digit 3 proximal depth def: "IAO:0000423" [] def: "The depth of the proximal end of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002099 ! metacarpal bone proximal depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0002141 name: distal phalanx of manual digit 3 circumference def: "The circumference of a distal phalanx of manual digit 3." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of the central digit circumference of the sole (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002143 ! distal phalanx of digit 3 circumference is_a: OBA:0002939 ! distal phalanx of manual digit 3 size intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0004312 ! inheres in distal phalanx of manual digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002142 name: distal phalanx of pedal digit 3 circumference def: "The circumference of a distal phalanx of pedal digit 3." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of the central digit circumference of the sole (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002143 ! distal phalanx of digit 3 circumference is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0004317 ! inheres in distal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002143 name: distal phalanx of digit 3 circumference def: "The circumference of a distal phalanx of digit 3." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of the central digit circumference of the sole (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002674 ! phalanx size is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0014485 ! inheres in distal phalanx of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0014485 ! inheres in distal phalanx of digit 3 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002144 name: distal phalanx of manual digit 2 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002966 ! distal phalanx of manual digit 2 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002145 name: distal phalanx of pedal digit 2 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002172 ! distal phalanx of pedal digit 2 depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002146 name: distal phalanx of digit 2 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002674 ! phalanx size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0014484 ! inheres in distal phalanx of digit 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002147 name: distal phalanx of manual digit 2 diagonal length def: "The length of the distal phalanx of manual digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:0002970 ! distal phalanx of manual digit 2 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002148 name: distal phalanx of pedal digit 2 diagonal length def: "The length of the distal phalanx of pedal digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: FOVT:0001820 ! distal phalanx of pedal digit 2 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002149 name: distal phalanx of digit 2 diagonal length def: "The length of the distal phalanx of digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:VT0002543 ! phalanx length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0014484 ! inheres in distal phalanx of digit 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002150 name: distal phalanx of manual digit 2 middle breadth def: "The width of the middle of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002153 ! distal phalanx of manual digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002151 name: distal phalanx of pedal digit 2 middle breadth def: "The width of the middle of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002154 ! distal phalanx of pedal digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002152 name: distal phalanx of digit 2 middle breadth def: "The width of the middle of a distal phalanx of digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002155 ! distal phalanx of digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002153 name: distal phalanx of manual digit 2 breadth def: "The width of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002155 ! distal phalanx of digit 2 breadth is_a: OBA:0002966 ! distal phalanx of manual digit 2 size intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004311 ! inheres in distal phalanx of manual digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002154 name: distal phalanx of pedal digit 2 breadth def: "The width of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002155 ! distal phalanx of digit 2 breadth is_a: OBA:0003135 ! distal phalanx of pedal digit 2 size intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004316 ! inheres in distal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002155 name: distal phalanx of digit 2 breadth def: "The width of a distal phalanx of digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0002674 ! phalanx size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0014484 ! inheres in distal phalanx of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0014484 ! inheres in distal phalanx of digit 2 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002156 name: distal phalanx of digit 4 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002674 ! phalanx size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0014486 ! inheres in distal phalanx of digit 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002157 name: distal phalanx of manual digit 4 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002919 ! distal phalanx of manual digit 4 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002158 name: distal phalanx of pedal digit 4 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002174 ! distal phalanx of pedal digit 4 depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002159 name: distal phalanx of manual digit 4 diagonal length def: "The length of the distal phalanx of manual digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:0002918 ! distal phalanx of manual digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002160 name: distal phalanx of pedal digit 4 diagonal length def: "The length of the distal phalanx of pedal digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: FOVT:0001807 ! distal phalanx of pedal digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002161 name: distal phalanx of digit 4 diagonal length def: "The length of the distal phalanx of digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:VT0002543 ! phalanx length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0014486 ! inheres in distal phalanx of digit 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002162 name: distal phalanx of manual digit 4 middle breadth def: "The width of the middle of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002166 ! distal phalanx of manual digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002163 name: distal phalanx of pedal digit 4 middle breadth def: "The width of the middle of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002165 ! distal phalanx of pedal digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002164 name: distal phalanx of digit 4 middle breadth def: "The width of the middle of a distal phalanx of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002167 ! distal phalanx of digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002165 name: distal phalanx of pedal digit 4 breadth def: "The width of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002167 ! distal phalanx of digit 4 breadth is_a: OBA:0003367 ! distal phalanx of pedal digit 4 size intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004318 ! inheres in distal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002166 name: distal phalanx of manual digit 4 breadth def: "The width of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002167 ! distal phalanx of digit 4 breadth is_a: OBA:0002919 ! distal phalanx of manual digit 4 size intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004313 ! inheres in distal phalanx of manual digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002167 name: distal phalanx of digit 4 breadth def: "The width of a distal phalanx of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0002674 ! phalanx size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0014486 ! inheres in distal phalanx of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0014486 ! inheres in distal phalanx of digit 4 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002168 name: distal phalanx of pedal digit 3 articular breadth def: "The width of the articular surface of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalnx 3 breadth of the facies articularis (BF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of the central digit articular breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002169 name: distal phalanx of pedal digit 3 articular depth def: "The depth of the articular surface of a distal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 length of the facies articularis (LF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of the central digit articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002170 name: distal phalanx of pedal digit 3 height def: "The height of a distal phalanx of pedal digit 3 along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "phalanx 3 height in the region of the extensor process (HP)" RELATED [ISBN:9780873659505] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0004317 ! inheres in distal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002171 name: obsolete distal phalanx of pedal digit 3 circumference comment: term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0002143 [Term] id: FOVT:0002172 name: distal phalanx of pedal digit 2 depth def: "The depth of a distal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0003135 ! distal phalanx of pedal digit 2 size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004316 ! inheres in distal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002173 name: navicular breadth def: "The width of a navicular along the medial-lateral axis." [ISBN:9780873659505] synonym: "navicular greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0002564 ! tarsal bone size is_a: OBA:0004840 ! navicular bone of pes morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001451 ! inheres in navicular bone of pes relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0001451 ! inheres in navicular bone of pes property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002174 name: distal phalanx of pedal digit 4 depth def: "The depth of a distal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "phalnx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0003367 ! distal phalanx of pedal digit 4 size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: RO:0000052 UBERON:0004318 ! inheres in distal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002175 name: obsolete distal phalanx of pedal digit 2 breadth def: "OBSOLETE. The width of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0002154 [Term] id: FOVT:1000000 name: calcar length def: "Length of a spur of cartilage arising from the inner side of the ankle and running along part of the outer interfemoral membrane in bats." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://en.wikipedia.org/wiki/Calcar"} is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0004155 ! skeletal system morphology is_a: OBA:VT0015071 ! appendage morphology trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0010869 ! inheres in calcar relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: RO:0000052 UBERON:0010869 ! inheres in calcar property_value: dcterms:created "2026-02-10T22:04:40Z" xsd:dateTime [Term] id: FOVT:1000001 name: tragus length def: "Length of a pointed eminence of the external ear, situated in front of the concha, and projecting backward over the meatus." [] {IAO:0000119="https://en.wikipedia.org/wiki/Tragus_(ear)", IAO:0000119="https://ranges-network.org/traits/"} is_a: OBA:0003232 ! tragus size is_a: OBA:0003426 ! external ear length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0010887 ! inheres in tragus relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-10T22:26:35Z" xsd:dateTime [Term] id: FOVT:1000002 name: uterine embryo count def: "Measurement datum about the number of embryos observed in a uterus." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://doi.org/10.1203/01.PDR.0000112034.98387.B2"} is_a: IAO:0000109 ! measurement datum relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: IAO:0000136 UBERON:0000995 ! is about uterus property_value: dcterms:created "2026-02-10T22:30:45Z" xsd:dateTime [Term] id: FOVT:1000003 name: left uterine embryo count def: "Embryo count of embryos observed in left horn of uterus." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://doi.org/10.1203/01.PDR.0000112034.98387.B2"} is_a: FOVT:1000002 ! uterine embryo count relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: IAO:0000136 UBERON:0009020 ! is about left uterine horn property_value: dcterms:created "2026-02-10T22:34:45Z" xsd:dateTime [Term] id: FOVT:1000004 name: right uterine embryo count def: "Embryo count of embryos observed in right horn of uterus." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://doi.org/10.1203/01.PDR.0000112034.98387.B2"} is_a: FOVT:1000002 ! uterine embryo count relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: IAO:0000136 UBERON:0009022 ! is about right uterine horn property_value: dcterms:created "2026-02-10T22:35:31Z" xsd:dateTime [Term] id: FOVT:1000005 name: reproduction data item def: "Data item about entities related to biological reproduction." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://en.wikipedia.org/wiki/Reproduction"} is_a: IAO:0000027 ! data item relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-19T20:50:31Z" xsd:dateTime [Term] id: FOVT:1000006 name: left testis width def: "Testis width of left male gonad spheroid (perpendicular to long axis at midpoint)." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://en.wikipedia.org/wiki/Testicle"} is_a: FOVT:0001368 ! testis width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004533 ! inheres in left testis relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: RO:0000052 UBERON:0004533 ! inheres in left testis property_value: dcterms:created "2026-02-10T22:48:27Z" xsd:dateTime [Term] id: FOVT:1000007 name: right testis width def: "Testes width of right male gonad spheroid (perpendicular to long axis at midpoint)." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://en.wikipedia.org/wiki/Testicle"} is_a: FOVT:0001368 ! testis width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004534 ! inheres in right testis relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: RO:0000052 UBERON:0004534 ! inheres in right testis property_value: dcterms:created "2026-02-10T22:48:39Z" xsd:dateTime [Term] id: FOVT:1000008 name: embryonic curvilinear length def: "Length from the crown of the head to bottom of the rump of a fetus or embryo, taken along the spinal curvature." [] {IAO:0000119="https://doi.org/10.3354/meps", IAO:0000119="https://ranges-network.org/traits/"} is_a: FOVT:1000010 ! embryonic body length relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-19T20:52:56Z" xsd:dateTime [Term] id: FOVT:1000009 name: embryonic crown-rump length def: "Length from the crown of the head to bottom of the rump of a fetus or embryo, taken in straight line along body axis." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://doi.org/10.1002/uog.7654"} is_a: FOVT:1000010 ! embryonic body length relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-19T20:53:43Z" xsd:dateTime [Term] id: FOVT:1000010 name: embryonic body length def: "Body length of an embryo." [] is_a: OBA:VT0001256 ! body length is_a: OBA:VT0001697 ! embryo size trait intersection_of: OBA:VT0001256 ! body length intersection_of: RO:0000052 UBERON:0000922 ! inheres in embryo relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-19T20:54:27Z" xsd:dateTime [Term] id: FOVT:1000011 name: ear length from crown def: "The length of a line of an ear from the dorsal end of the base of the ear to the tip of the pinna." [] {IAO:0000119="https://ranges-network.org/traits/", dcterms:source="ISBN-10: 1016175078 (p. 602)"} is_a: OBA:0003426 ! external ear length relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-24T22:14:26Z" xsd:dateTime [Term] id: FOVT:1000012 name: vaginal perforation def: "Vaginal development trait wherein an epithelial membrane fusing the vaginal orifice closed recedes from the center, thereby opening the vaginal orifice. Indicative of sexual maturity in some organisms, such as rodents." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="https://doi.org/10.1007/s42991-025-00520-z"} synonym: "vaginal opening" RELATED [] is_a: GO:0060068 ! vagina development relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-18T17:14:25Z" xsd:dateTime [Term] id: FOVT:1000013 name: closed vagina orifice def: "Vagina orifice which is not patent, preventing insertion of a penis." [] {IAO:0000119="https://doi.org/10.1007/s42991-025-00520-z"} is_a: UBERON:0012317 ! vagina orifice intersection_of: UBERON:0012317 ! vagina orifice intersection_of: RO:0000053 PATO:0000608 ! bearer of closed relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: RO:0000053 PATO:0000608 ! bearer of closed property_value: dcterms:created "2026-02-18T18:37:45Z" xsd:dateTime [Term] id: FOVT:1000014 name: open vagina orifice def: "Vagina orifice which is patent, permitting insertion of a penis. May indicate the onset of estrus in some animals, such as in rodents." [] {IAO:0000119="https://doi.org/10.1007/s42991-025-00520-z"} is_a: UBERON:0012317 ! vagina orifice intersection_of: UBERON:0012317 ! vagina orifice intersection_of: RO:0000053 PATO:0000610 ! bearer of open relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: RO:0000053 PATO:0000610 ! bearer of open property_value: dcterms:created "2026-02-18T18:37:54Z" xsd:dateTime [Term] id: FOVT:1000015 name: closed vagina orifice due to mating plug def: "Closed vagina orifice which is closed due to a mating plug formed by male ejaculation. Indicative of recent copulation." [] {IAO:0000119="https://doi.org/10.1073/pnas.1920526117"} is_a: FOVT:1000013 ! closed vagina orifice intersection_of: FOVT:1000013 ! closed vagina orifice intersection_of: attaches_to UBERON:0010148 ! mating plug relationship: attaches_to UBERON:0010148 ! mating plug relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 property_value: dcterms:created "2026-02-18T21:42:33Z" xsd:dateTime [Term] id: FOVT:1000018 name: placental scar def: "Reproductive structure which is a remnant of a previous placenta implantation site and appears as a discolored portion of the uterine wall. Commonly observed in rodents." [] {IAO:0000119="DOI: 10.9734/AJRIZ/2018/v1i11100"} is_a: UBERON:0005156 ! reproductive structure relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: output_of GO:0007565 ! female pregnancy relationship: part_of UBERON:0000459 ! uterine wall property_value: dcterms:created "2026-02-18T22:41:08Z" xsd:dateTime [Term] id: FOVT:1000019 name: placental scar count def: "Measurement datum about the number of placental scars observed in a uterus." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="\"The Placental Scar as a Measure of Fertility in Rats\" https://www.jstor.org/stable/3796411"} is_a: IAO:0000109 ! measurement datum relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: IAO:0000136 UBERON:0000995 ! is about uterus property_value: dcterms:created "2026-02-19T17:18:15Z" xsd:dateTime [Term] id: FOVT:1000020 name: left placental scar count def: "Placental scar count about the number of placental scars observed in left horn of uterus." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="\"The Placental Scar as a Measure of Fertility in Rats\" https://www.jstor.org/stable/3796411"} is_a: FOVT:1000019 ! placental scar count relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: IAO:0000136 UBERON:0009020 ! is about left uterine horn property_value: dcterms:created "2026-02-19T17:20:10Z" xsd:dateTime [Term] id: FOVT:1000021 name: right placental scar count def: "Placental scar count about the number of placental scars observed in right horn of uterus." [] {IAO:0000119="https://ranges-network.org/traits/", IAO:0000119="\"The Placental Scar as a Measure of Fertility in Rats\" https://www.jstor.org/stable/3796411"} is_a: FOVT:1000019 ! placental scar count relationship: dc-contributor https://orcid.org/0009-0002-7282-0836 relationship: IAO:0000136 UBERON:0009022 ! is about right uterine horn property_value: dcterms:created "2026-02-19T17:21:28Z" xsd:dateTime [Term] id: FOVT:2000000 name: choana length def: "The length of a posterior nasal aperture of the interal naris (choana) along anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "choanal length (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0002236 ! internal nares morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004771 ! inheres in posterior nasal aperture relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0004771 ! inheres in posterior nasal aperture property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000001 name: choana minimal breadth def: "The length of the posterior portion of a posterior nasal aperture of the internal naris (choana) along left-right axis." [ISBN:9004086161\, 9789004086166] synonym: "choana minimal width" EXACT [] synonym: "minimal breadth of the choanae (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0002236 ! internal nares morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000002 name: choana maximal breadth def: "The length along the midline of a posterior nasal aperture of the internal naris (choana) along left-right axis." [ISBN:9004086161\, 9789004086166] synonym: "choanal maximal width" EXACT [] synonym: "maximal breadth of the choanae (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0002236 ! internal nares morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0004771 ! inheres in posterior nasal aperture relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0004771 ! inheres in posterior nasal aperture property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000003 name: muzzle minimal breadth def: "The length of a muzzle between the middle of the right and left diastema of an upper jaw." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is measurement 47 for Equus in von den Driesch (1979). {xref="ISBN:9780873659505"} synonym: "least breadth in the region of the diastema" RELATED [ISBN:9780873659505] synonym: "minimal muzzle breadth (M14)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "muzzle minimal width" EXACT [] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0000443 ! snout morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0006333 ! inheres in snout relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0006333 ! inheres in snout property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000004 name: supraoccipital crest length def: "The length of a supraoccipital crest along the left-right axis." [ISBN:9004086161\, 9789004086166] synonym: "occipital breadth (M20)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:2000060 ! neurocranium length is_a: OBA:0003980 ! supraoccipital bone size is_a: OBA:VT0003104 ! skull size trait intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:2001783 ! inheres in supraoccipital crest relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:2001783 ! inheres in supraoccipital crest property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000005 name: foramen magnum breadth def: "The length of a foramen magnum along the left-right axis." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 36 Equus, 21 Camelus, 28 Bos, 29 Ovis and Capra, 28 Cervus, 36 Sus, 27 Canis and Ursus, 20 Felis. {xref="ISBN:9780873659505"} synonym: "foramen magnum width" EXACT [] synonym: "greatest breadth of foramen magnum" RELATED [ISBN:9780873659505] is_a: OBA:0002346 ! foramen magnum size is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0003687 ! inheres in foramen magnum relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000006 name: foramen magnum height def: "The length of a foramen magnum along the midsagittal plane." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 37 Equus, 22 Camelus, 29 Bos, 30 Ovis and Capra, 29 Cervus, 37 Sus, 28 Canis and Ursus, 21 Felis. {xref="ISBN:9780873659505"} synonym: "height of the foramen magnum" RELATED [ISBN:9780873659505] is_a: OBA:0002346 ! foramen magnum size is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0003687 ! inheres in foramen magnum relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000007 name: occipital breadth def: "The length between the right and left temporal fossa of the occipital region of a skull." [ISBN:9780873659505] comment: This is measurement 30 for Bos in von den Driesch (1979). {xref="ISBN:9780873659505"} synonym: "least occipital breadth" RELATED [ISBN:9780873659505] synonym: "occipital width" EXACT [] is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0005902 ! inheres in occipital region relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0005902 ! inheres in occipital region property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000008 name: basicranium length def: "The length of a basicranium." [ISBN: 9780873659505] is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000009 name: basicranium length from hormion def: "The length of a basicranium from a hormion to a basion." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The measurement number and genus in von den Driesch (1979): 5 Equus, 5 Camelus, 6 Sus. synonym: "basicranial axis to hormion length" RELATED [ISBN: 9780873659505] synonym: "post-vomerine length (M4)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000008 ! basicranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 [Term] id: FOVT:2000010 name: basicranium length from synsphenion def: "The length of a skull from synsphenion to basion." [ISBN: 9780873659505] comment: The measurement number and genus from von den Driesch (1979): 6 Cervus, 4 Canis and Ursus, 4 Felis. {xref="ISBN: 9780873659505"} synonym: "basicranial axis to synphenion length" RELATED [ISBN: 9780873659505] is_a: FOVT:2000008 ! basicranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9859 [Term] id: FOVT:2000011 name: bony part of hard palate breadth def: "The length of a bony part of hard palate along the left-right axis." [ISBN: 9004086161\, 9789004086166] comment: bony part of hard palate width synonym: "palatal breadth (M13)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:0003100 ! hard palate size is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0012074 ! inheres in bony part of hard palate relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0012074 ! inheres in bony part of hard palate property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000012 name: bony part of hard palate length def: "The length of a bony part of a hard palate along the left-right axis." [ISBN: 9004086161\, 9789004086166] comment: This measurement is taken along the midsagittal plane afrom the anteriormost part of the cheekteeth to a anteriormost part of the choanal groove. synonym: "palatal length (M2)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000014 ! post-palatal length is_a: OBA:0002546 ! facial skeleton size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0012074 ! inheres in bony part of hard palate relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0012074 ! inheres in bony part of hard palate property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000013 name: vomer ventral length def: "The length of a vomer from anteriormost part of a choanal groove to a hormion." [ISBN: 9004086161\, 9789004086166] synonym: "vomerine length (M2)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:0004900 ! vomer size is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002396 ! inheres in vomer relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000014 name: post-palatal length def: "The length of a line from choanal groove to basion of a cranium." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The measurement number and genus from von den Driesch (1979) are: 17 Equus, 9 Camelus, 16 Sus. {xref="ISBN: 9780873659505"} synonym: "basion to staphylion length" RELATED [ISBN: 9780873659505] synonym: "post-palatal length (M5)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: OBA:0003100 ! hard palate size is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003216 ! inheres in hard palate relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 [Term] id: FOVT:2000015 name: occipital region height from opisthion def: "The length of an occipital region from an opisthion to an akrocranion." [ISBN: 9780873659505, ISBN:9004086161\, 9789004086166] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 41 Bos. {xref="ISBN: 9780873659505"} synonym: "least height of the occipital region" RELATED [ISBN:9780873659505] synonym: "occipital height (M22)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:2000020 ! occipital region height relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000016 name: occipital region height from basion def: "The length of an occipital region from a basion to the heighest point of a sagittal crest in projection." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 50 Equus, 30 Camelus, 40 Bos, 38 Cervus, 38 Canis and Ursus. {xref="ISBN:9780873659505"} synonym: "basion height" RELATED [] synonym: "cranial height (M26)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "skull height" RELATED [] is_a: FOVT:2000020 ! occipital region height relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000017 name: cranium dorsal length def: "The length of the dorsal side of a cranium along the anterior-posterior axis." [ISBN:9780873659505] comment: In pigs, the dorsalmost point, the opisthocranion, is projected into space. {xref="ISBN:9780873659505"} comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 1 Equus, 1 Camelus, 1 Bos, 1 Ovis and Capra, 1 Cervus, 1 Sus, 1 Canis and Ursus, 1 Felis, 1 Lepus and Oryctolagus {xref="ISBN:9780873659505"} synonym: "cranium greatest length" RELATED [ISBN:9780873659505] synonym: "cranium profile length" RELATED [ISBN:9780873659505] synonym: "cranium total length" RELATED [ISBN:9780873659505] is_a: OBA:0005564 ! cranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000018 name: cranium ventral length from occipital condyle def: "The length of the ventral side of a cranium from an occipital condyle to a prosthion." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 2 Equus, 2 Camelus, 2 Bos, 2 Ovis and Capra, 2 Cervus, 2 Sus, 2 Canis and Ursus, 2 Felis, 2 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "condylobasal length" RELATED [ISBN:9780873659505] is_a: OBA:0005564 ! cranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000019 name: cranium ventral length from basion def: "The length of the ventral side of a cranium from a basion to a prosthion." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 3 Equus, 3 Camelus, 3 Bos, 3 Ovis and Capra, 3 Cervus, 3 Sus, 3 Canis and Ursus, 3 Felis, 3 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "basal length" RELATED [ISBN:9780873659505] is_a: OBA:0005564 ! cranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000020 name: occipital region height def: "The length of an occipital region along the midsagittal axis." [ISBN: 9780873659505] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0005902 ! inheres in occipital region relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0005902 ! inheres in occipital region property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000021 name: cranium breadth def: "The breadth of a skull." [] is_a: OBA:VT0010613 ! cranium size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0003128 ! inheres in cranium relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000022 name: cranium breadth at ectorbitale def: "The length of a cranium between the right and left ectorbitale." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: in Lepus and Oryctolagus: breadth at temporal fossae dorsal of the zygomatic processes of the temporal bone {xref="ISBN: 9004086161, 9789004086166"} comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 41 Equus, 25 Camelus, 33 Bos, 34 Ovis and Capra, 32 Cervus, 41 Sus, 32 Canis and Ursus, 24 Felis. synonym: "ectorbitale to ectorbitale" RELATED [ISBN: 9004086161\, 9789004086166] synonym: "frontal breadth (M18)" RELATED [ISBN: 9780873659505] synonym: "greatest breadth across orbits" RELATED [ISBN: 9004086161\, 9789004086166] synonym: "greatest breadth of skull" RELATED [ISBN: 9004086161\, 9789004086166] synonym: "greatest frontal breadth" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:338152 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000023 name: cranium breadth at zygomatic arch def: "The length of a cranium from a left to a right zygion." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 34 Cervus, 43 Sus, 30 Canis and Ursus, 23 Felis. {xref="ISBN: 9004086161, 9789004086166"} synonym: "bizygomatic breadth (M19)" RELATED [ISBN: 9780873659505] synonym: "zygomatic breadth" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9859 [Term] id: FOVT:2000024 name: cranium breadth at paroccipital process def: "The length of a cranium from a left to a right paroccipital process." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 35 Equus, 20 Camelus, 27 Bos, 28 Ovis and Capra, 27 Cervus, 35 Sus, 26 Canis, 26 Ursus. {xref="ISBN: 9004086161, 9789004086166"} synonym: "basioccipital breadth (M21)" RELATED [ISBN: 9780873659505] synonym: "greatest breadth at the bases of the paraoccipital processes" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor http://purl.obolibrary.org/obo/fovt.owl# property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000051 name: cranium ventral length from incisors def: "The length of a cranium from a basion to an anatomical point between first incisors." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 3a Equus. {xref="ISBN:9780873659505"} synonym: "basilar length (M6)" RELATED [ISBN:9780873659505] is_a: OBA:0005564 ! cranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000052 name: external acoustic meatus height def: "The length of an external acoustic meatus along the upper-lower axis." [ISBN:9004086161\, 9789004086166] synonym: "exterior height of the meatus auditivus externus (M27)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002080 ! external acoustic meatus size is_a: OBA:VT0010517 ! neurocranium size trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0001352 ! inheres in external acoustic meatus relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000053 name: cranium breadth at occipital condyle def: "The length of a cranium from a left to a right occipital condyle." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 34 Equus, 19 Camelus, 26 Bos, 27 Ovis and Capra, 26 Cervus, 34 Sus, 25 Canis and Ursus, 19 Felis, 12 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "greatest breadth of the occipital condyles" RELATED [ISBN:9780873659505] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000054 name: cranium breadth at mastoid process of temporal bone comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 33 Equus, 18 Camelus, 25 Bos, 26 Ovis and Capra, 25 Cervus, 33 Sus, 23 Canis and Ursus, 18 Felis, 13 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "greatest mastoid breadth" RELATED [ISBN:9780873659505] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 property_value: measured_in_taxon "The length of a cranium from a left to a right othion." xsd:string {xref="ISBN:9780873659505"} [Term] id: FOVT:2000055 name: occipital region height from akrokranion def: "The length of an occipital region from a basion to an akrokranion." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 45 Sus, 40 Canis and Ursus, 32 Felis {xref="ISBN:9780873659505"} synonym: "height of the occipital region" RELATED [ISBN:9780873659505] synonym: "height of the occipital triangle" RELATED [ISBN:9780873659505] is_a: FOVT:2000020 ! occipital region height relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:2000056 name: cranium breadth at temporal crest def: "The length of a basicranium along the left-right axis." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 38 Sus. {xref="ISBN:9780873659505"} comment: This is the narrowest points of the temporal crest. synonym: "least breadth of the squamous part of the occipital bone" RELATED [ISBN:9780873659505] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:2000057 name: basicranium length from ethmoid foramen def: "The length of a basicranium from a basion to an ethmoid foramen." [ISBN:9004086161\, 9789004086166] synonym: "length between basion and foramen ethmoidalis (M17)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:2000008 ! basicranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000058 name: neurocranium breadth aboral to orbit of skull def: "The length of a neurocranium along the left-right axis." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 39 Equus, 24 Camelus, 32 Bos, 31 Cervus, 31 Canis and Ursus. {xref="ISBN:9780873659505"} comment: This is the narrowest points of the neurocranium aboral to orbit of skull. synonym: "least breadth of forehead aboral to orbits" RELATED [ISBN:9780873659505] synonym: "least breadth of skull" RELATED [ISBN:9780873659505] synonym: "least frontal breadth" RELATED [ISBN:9780873659505] is_a: FOVT:2000059 ! neurocranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000059 name: neurocranium breadth def: "The length of a neurocranium along the left-right axis." [] is_a: OBA:VT0010517 ! neurocranium size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: RO:0000052 UBERON:0001703 ! inheres in neurocranium relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000060 name: neurocranium length def: "The length of a neurocranium along the anterior-posterior axis." [] is_a: OBA:VT0010517 ! neurocranium size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001703 ! inheres in neurocranium relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000061 name: neurocranium breadth at euryon def: "The length of a neurocranium from a left euryon to a right euryon." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 38 Equus, 23 Camelus, 33 Ovis and Capra, 30 Cervus, 29 Canis and Ursus, 22 Felis, 14 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "greatest breadth across the orbit" RELATED [ISBN:9780873659505] synonym: "greatest breadth of braincase" RELATED [ISBN:9780873659505] synonym: "greatest neurocranium breadth" RELATED [ISBN:9780873659505] is_a: FOVT:2000059 ! neurocranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000062 name: neurocranium breadth at temporal crest def: "The length of a neurocranium along the left-right axis." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 38 Sus. {xref="ISBN:9780873659505"} comment: This is the widest points of the temporal crest. synonym: "greatest breadth of the squamous part of the occipital bone" RELATED [ISBN:9780873659505] is_a: FOVT:2000059 ! neurocranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:2000063 name: neurocranium breadth at temporal line def: "The length of a neurocranium along the left-right axis." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 31 Ovis and Capra, 40 Sus. {xref="ISBN:9780873659505"} comment: This is the narrowest points between the temporal lines. synonym: "least breadth between the temporal lines" RELATED [ISBN:9780873659505] synonym: "least breadth of parietal" RELATED [ISBN:9780873659505] is_a: FOVT:2000059 ! neurocranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000064 name: neurocranium lateral breadth at horn def: "The length of a neurocranium from a left to a right horn." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 32 Ovis and Capra. {xref="ISBN:9780873659505"} comment: This is between the lateral border of the bases of the horns. {xref="ISBN:9780873659505"} synonym: "greatest breadth between lateral borders of the horncore bases" RELATED [ISBN:9780873659505] is_a: FOVT:2000059 ! neurocranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000065 name: neurocranium length from akrokranion def: "The length of a neurocranium from an akrokranion to a supreorbitale." [ISBN:9780873659505] comment: In Canis, Ursus and Felis the measurement is taken from an akrokranion to a frontal midpoint (the midsagittal point between left and rigth ectorbitale). {xref="ISBN:9780873659505"} comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 9 Equus, 11 Ovis and Capra, 11 Sus, 7 Canis and Ursus, 7 Felis. {xref="ISBN:9780873659505"} synonym: "upper neurocranium length" RELATED [ISBN:9780873659505] is_a: FOVT:2000060 ! neurocranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000066 name: neurocranium length from basion def: "The length of a neurocranium from a basion to a nasion" [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 7 Equus, 6 Bos, 6 Ovis and Capra, 8 Cervus, 8 Sus, 6 Canis and Ursus, 6 Felis. {xref="ISBN:9780873659505"} comment: this measurement can be taken only with curved callipers {xref="ISBN:9780873659505"} synonym: "neurocranium length" RELATED [ISBN:9780873659505] is_a: FOVT:2000060 ! neurocranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000067 name: neurocranium length from bregma def: "The length of a neurocranium from a bregma to an akrokranion." [ISBN:9780873659505] comment: In Lepus and Oryctolagus this measurement is taken from bregma to an anatomical point connecting sagittal and lambdoidal sutures comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 9 Ovis and Capra, 13 Sus, 6 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "parietal length" RELATED [ISBN:9780873659505] is_a: FOVT:2000060 ! neurocranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000068 name: neurocranium length from ectorbitale def: "The length of a neurocranium from an ectorbitale to an akrokranion." [ISBN:9004086161\, 9789004086166] synonym: "posterior ocular line (M24)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:2000060 ! neurocranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000069 name: neurocranium length from entorbitale def: "The length of a neurocranium from an entorbitale to an aboral border of occipital condyle." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 13 Bos. {xref="ISBN:9780873659505"} synonym: "from the aboral border of one occipital condyle to the entorbitale of the same side" RELATED [ISBN:9780873659505] is_a: FOVT:2000060 ! neurocranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000070 name: neurocranium length from opisthion def: "The length of a neurocranium from an opisthion to an ectorbitale." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 14 Equus, 7 Camelus, 11 Canis and Ursus. {xref="ISBN:9780873659505"} synonym: "length of braincase" RELATED [ISBN:9780873659505] is_a: FOVT:2000060 ! neurocranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9836 [Term] id: FOVT:2000071 name: neurocranium medial breadth at horn def: "The length of a neurocranium from a left to a right horn." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 31 Bos. {xref="ISBN:9780873659505"} comment: This is between the medial border of the bases of the horns. synonym: "least breadth between the bases of the hornocores" RELATED [ISBN:9780873659505] is_a: FOVT:2000059 ! neurocranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000072 name: temporal fossa height def: "The length of a temporal fossa along the upper-lower axis." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 39 Bos. {xref="ISBN:9780873659505"} comment: this is the narrowest points of the temporal groove synonym: "least inner height of the temporal groove" RELATED [ISBN:9780873659505] is_a: OBA:VT0010003 ! bone morphology trait is_a: OBA:VT0010517 ! neurocranium size trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0013463 ! inheres in temporal fossa relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0013463 ! inheres in temporal fossa property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000073 name: temporal fossa ventral length def: "The length of the ventral side of a temporal fossa along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "length of fossa temporalis (M16)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:2000060 ! neurocranium length is_a: OBA:VT0010003 ! bone morphology trait intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0013463 ! inheres in temporal fossa relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: RO:0000052 UBERON:0013463 ! inheres in temporal fossa property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: GO:0000011 name: vacuole inheritance def: "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:14616069] is_a: GO:0007033 ! vacuole organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: results_in_distribution_of GO:0005773 ! vacuole relationship: results_in_distribution_of GO:0005773 ! vacuole property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0000048 name: peptidyltransferase activity def: "Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme." [PMID:11433365, PMID:9242921] xref: EC:2.3.2.12 xref: MetaCyc:PEPTIDYLTRANSFERASE-RXN xref: Reactome:R-HSA-156912 "Peptide transfer from P-site tRNA to the A-site tRNA" is_a: GO:0016755 ! aminoacyltransferase activity is_a: GO:0140096 ! catalytic activity, acting on a protein is_a: GO:0140101 ! catalytic activity, acting on a tRNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22192" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25493" xsd:anyURI [Term] id: GO:0000070 name: mitotic sister chromatid segregation alt_id: GO:0016359 def: "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, GOC:jl] subset: goslim_pombe synonym: "mitotic chromosome segregation" EXACT [] synonym: "mitotic sister-chromatid adhesion release" NARROW [] xref: Reactome:R-HSA-2500257 "Resolution of Sister Chromatid Cohesion" is_a: GO:0000819 ! sister chromatid segregation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0140014 ! mitotic nuclear division relationship: part_of GO:0140014 ! mitotic nuclear division [Term] id: GO:0000139 name: Golgi membrane def: "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." [GOC:mah] synonym: "Golgi apparatus membrane" EXACT [] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005794 ! Golgi apparatus relationship: bounding_layer_of GO:0005794 ! Golgi apparatus relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005794 ! Golgi apparatus [Term] id: GO:0000226 name: microtubule cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] subset: goslim_pombe synonym: "microtubule cytoskeleton organisation" EXACT [GOC:mah] synonym: "microtubule cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007017 ! microtubule-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0015630 ! results in organization of microtubule cytoskeleton relationship: RO:0002592 GO:0015630 ! results in organization of microtubule cytoskeleton property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI [Term] id: GO:0000228 name: nuclear chromosome def: "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:dph, GOC:mah] subset: goslim_chembl subset: goslim_generic synonym: "nuclear interphase chromosome" NARROW [] is_a: GO:0005694 ! chromosome intersection_of: GO:0005694 ! chromosome intersection_of: part_of GO:0005634 ! nucleus relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0031981 ! nuclear lumen [Term] id: GO:0000271 name: polysaccharide biosynthetic process def: "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:go_curators] synonym: "glycan biosynthesis" EXACT [] synonym: "glycan biosynthetic process" EXACT [] synonym: "polysaccharide anabolism" EXACT [] synonym: "polysaccharide biosynthesis" EXACT [] synonym: "polysaccharide formation" EXACT [] synonym: "polysaccharide synthesis" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0016051 ! carbohydrate biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18154 ! has primary output polysaccharide relationship: RO:0004008 CHEBI:18154 ! has primary output polysaccharide [Term] id: GO:0000272 name: polysaccharide catabolic process alt_id: GO:0044244 def: "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [PMID:33139480] synonym: "multicellular organismal polysaccharide catabolic process" NARROW [] synonym: "polysaccharide breakdown" EXACT [] synonym: "polysaccharide catabolism" EXACT [] synonym: "polysaccharide degradation" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016052 ! carbohydrate catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0000278 name: mitotic cell cycle alt_id: GO:0007067 def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194] comment: Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_yeast synonym: "mitosis" RELATED [] xref: Reactome:R-HSA-69278 "Cell Cycle, Mitotic" xref: Wikipedia:Mitosis is_a: GO:0007049 ! cell cycle intersection_of: GO:0007049 ! cell cycle intersection_of: has_part GO:0140014 ! mitotic nuclear division relationship: has_part GO:0140014 ! mitotic nuclear division relationship: in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0000280 name: nuclear division def: "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." [GOC:mah] subset: goslim_pir synonym: "karyokinesis" RELATED [] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: results_in_fission_of GO:0005634 ! nucleus relationship: results_in_fission_of GO:0005634 ! nucleus [Term] id: GO:0000313 name: organellar ribosome def: "A ribosome contained within a subcellular membrane-bounded organelle." [GOC:mah, GOC:mcc] is_a: GO:0005840 ! ribosome intersection_of: GO:0005840 ! ribosome intersection_of: part_of GO:0043226 ! organelle relationship: part_of GO:0043226 ! organelle [Term] id: GO:0000578 name: embryonic axis specification def: "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo." [GOC:dph, GOC:go_curators, GOC:sdb_2009, GOC:tb] synonym: "embryonic axis determination" RELATED [] is_a: GO:0009798 ! axis specification is_a: GO:0009880 ! embryonic pattern specification property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0000740 name: nuclear membrane fusion def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus." [GOC:elh] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: RO:0012008 GO:0031965 ! results in fusion of nuclear membrane relationship: RO:0012008 GO:0031965 ! results in fusion of nuclear membrane [Term] id: GO:0000741 name: karyogamy alt_id: GO:0007335 def: "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." [GOC:elh] synonym: "nuclear fusion" EXACT [] synonym: "nuclear fusion during karyogamy" EXACT [] xref: Wikipedia:Karyogamy is_a: GO:0006997 ! nucleus organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0048284 ! organelle fusion intersection_of: RO:0012008 GO:0005634 ! results in fusion of nucleus relationship: part_of GO:0006997 ! nucleus organization relationship: RO:0012008 GO:0005634 ! results in fusion of nucleus [Term] id: GO:0000768 name: syncytium formation by plasma membrane fusion def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mtg_muscle, GOC:tb] synonym: "cell fusion" BROAD [] is_a: GO:0006949 ! syncytium formation is_a: GO:0140253 ! cell-cell fusion intersection_of: GO:0006949 ! syncytium formation intersection_of: has_part GO:0045026 ! plasma membrane fusion [Term] id: GO:0000785 name: chromatin alt_id: GO:0000789 alt_id: GO:0000790 alt_id: GO:0005717 def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." [GOC:elh, PMID:20404130] comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. synonym: "chromosome scaffold" RELATED [] synonym: "cytoplasmic chromatin" NARROW [] synonym: "nuclear chromatin" NARROW [] xref: NIF_Subcellular:sao1615953555 is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005694 ! chromosome property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28301" xsd:anyURI [Term] id: GO:0000792 name: heterochromatin alt_id: GO:0005720 alt_id: GO:0035328 def: "A compact and highly condensed form of chromatin that is refractory to transcription." [PMID:32017156] synonym: "nuclear heterochromatin" NARROW [] synonym: "transcriptionally inactive chromatin" EXACT [] synonym: "transcriptionally silent chromatin" EXACT [] xref: NIF_Subcellular:sao581845896 xref: Wikipedia:Heterochromatin is_a: GO:0000785 ! chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22355" xsd:anyURI [Term] id: GO:0000819 name: sister chromatid segregation def: "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." [GOC:ai, GOC:elh] is_a: GO:0051276 ! chromosome organization is_a: GO:0098813 ! nuclear chromosome segregation [Term] id: GO:0000902 name: cell morphogenesis alt_id: GO:0007148 alt_id: GO:0045790 alt_id: GO:0045791 def: "The developmental process in which the size or shape of a cell is generated and organized." [GOC:clt, GOC:dph, GOC:go_curators, GOC:tb] subset: goslim_chembl subset: goslim_drosophila subset: goslim_yeast synonym: "cellular morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000000 ! results in morphogenesis of cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002298 CL:0000000 ! results in morphogenesis of cell [Term] id: GO:0001101 name: response to acid chemical def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:rn] comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead. subset: gocheck_do_not_annotate synonym: "response to acid" BROAD [] synonym: "response to acid anion" RELATED [] synonym: "response to oxoanion" RELATED [] is_a: GO:0042221 ! response to chemical [Term] id: GO:0001501 name: skeletal system development def: "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." [GOC:dph, GOC:jid, GOC:tb] synonym: "skeletal development" EXACT [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001434 ! results in development of skeletal system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0001434 ! results in development of skeletal system [Term] id: GO:0001503 name: ossification def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:mtg_mpo, PMID:17572649] comment: Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'. synonym: "bone biosynthesis" EXACT [] synonym: "bone formation" EXACT [] synonym: "osteogenesis" EXACT [] xref: Wikipedia:Ossification is_a: GO:0032501 ! multicellular organismal process intersection_of: GO:0032501 ! multicellular organismal process intersection_of: RO:0002297 UBERON:0001474 ! results in formation of anatomical entity bone element relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002297 UBERON:0001474 ! results in formation of anatomical entity bone element [Term] id: GO:0001507 name: acetylcholine catabolic process in synaptic cleft def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission." [GOC:ai] synonym: "acetylcholine breakdown in synaptic cleft" EXACT [] synonym: "acetylcholine degradation in synaptic cleft" EXACT [] is_a: GO:0006581 ! acetylcholine catabolic process intersection_of: GO:0006581 ! acetylcholine catabolic process intersection_of: BFO:0000066 GO:0043083 ! occurs in synaptic cleft relationship: BFO:0000066 GO:0043083 ! occurs in synaptic cleft relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0001508 name: action potential def: "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] comment: Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so. is_a: GO:0042391 ! regulation of membrane potential property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0001525 name: angiogenesis def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." [ISBN:0878932453] synonym: "blood vessel formation from pre-existing blood vessels" EXACT systematic_synonym [] xref: Wikipedia:Angiogenesis is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048514 ! blood vessel morphogenesis relationship: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel [Term] id: GO:0001539 name: cilium or flagellum-dependent cell motility def: "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." [GOC:cilia, GOC:hjd, GOC:krc] comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "ciliary or bacterial-type flagellar motility" RELATED [] synonym: "ciliary/flagellar motility" EXACT [] is_a: GO:0048870 ! cell motility property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0001553 name: luteinization def: "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] synonym: "luteal phase" RELATED [] xref: Wikipedia:Luteal_phase xref: Wikipedia:Luteinization is_a: GO:0022602 ! ovulation cycle process relationship: part_of GO:0008585 ! female gonad development [Term] id: GO:0001555 name: oocyte growth def: "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000023 ! results in growth of oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: RO:0002343 CL:0000023 ! results in growth of oocyte [Term] id: GO:0001556 name: oocyte maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." [GOC:devbiol, https://www.ncbi.nlm.nih.gov/books/NBK279054/] xref: Wikipedia:Oocyte_maturation is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000023 ! results in maturation of oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: RO:0002299 CL:0000023 ! results in maturation of oocyte [Term] id: GO:0001558 name: regulation of cell growth def: "Any process that modulates the frequency, rate, extent or direction of cell growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016049 ! regulates cell growth relationship: RO:0002211 GO:0016049 ! regulates cell growth [Term] id: GO:0001560 name: regulation of cell growth by extracellular stimulus def: "Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time." [GOC:dph] synonym: "interpretation of external signals that regulate cell growth" EXACT [] synonym: "regulation of cell growth by detection of exogenous stimulus" EXACT [] synonym: "regulation of cell growth by sensing of exogenous stimulus" EXACT [] synonym: "regulation of growth by exogenous signal" EXACT [] synonym: "regulation of growth by exogenous stimuli" EXACT [] synonym: "regulation of growth by exogenous stimulus" EXACT [] synonym: "regulation of growth by external signal" EXACT [] synonym: "regulation of growth by external stimuli" EXACT [] synonym: "regulation of growth by external stimulus" EXACT [] is_a: GO:0001558 ! regulation of cell growth intersection_of: GO:0001558 ! regulation of cell growth intersection_of: part_of GO:0051716 ! cellular response to stimulus relationship: part_of GO:0051716 ! cellular response to stimulus [Term] id: GO:0001568 name: blood vessel development def: "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." [GOC:hjd, UBERON:0001981] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001981 ! results in development of blood vessel relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001944 ! vasculature development relationship: RO:0002296 UBERON:0001981 ! results in development of blood vessel [Term] id: GO:0001569 name: branching involved in blood vessel morphogenesis def: "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." [GOC:dph] synonym: "patterning of blood vessels" BROAD [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: part_of GO:0048514 ! blood vessel morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001525 ! angiogenesis [Term] id: GO:0001570 name: vasculogenesis def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." [PMID:8999798] synonym: "vascular morphogenesis" EXACT [] xref: Wikipedia:Vasculogenesis is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048514 ! blood vessel morphogenesis relationship: RO:0002297 UBERON:0001981 ! results in formation of anatomical entity blood vessel [Term] id: GO:0001578 name: microtubule bundle formation def: "A process that results in a parallel arrangement of microtubules." [GOC:dph] synonym: "microtubule bundling" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0000057 GO:0005874 ! has participant microtubule relationship: RO:0002297 GO:0097427 ! results in formation of anatomical entity microtubule bundle [Term] id: GO:0001654 name: eye development alt_id: GO:0042460 def: "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." [GOC:jid, GOC:jl] xref: Wikipedia:Eye_development is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000970 ! results in development of eye relationship: part_of GO:0150063 ! visual system development relationship: RO:0002296 UBERON:0000970 ! results in development of eye [Term] id: GO:0001655 name: urogenital system development def: "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004122 ! results in development of genitourinary system relationship: has_part GO:0072001 ! renal system development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0004122 ! results in development of genitourinary system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI [Term] id: GO:0001656 name: metanephros development def: "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:bf, ISBN:0192800752] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000081 ! results in development of metanephros relationship: RO:0002296 UBERON:0000081 ! results in development of metanephros [Term] id: GO:0001657 name: ureteric bud development def: "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0072164 ! mesonephric tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000084 ! results in development of ureteric bud relationship: RO:0002296 UBERON:0000084 ! results in development of ureteric bud [Term] id: GO:0001658 name: branching involved in ureteric bud morphogenesis def: "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, PMID:16916378] synonym: "ureteric bud branching" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: part_of GO:0060675 ! ureteric bud morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060675 ! ureteric bud morphogenesis [Term] id: GO:0001659 name: temperature homeostasis def: "A homeostatic process in which an organism modulates its internal body temperature." [GOC:jl] synonym: "thermoregulation" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Thermoregulation is_a: GO:0048871 ! multicellular organismal-level homeostasis property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0001666 name: response to hypoxia def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:hjd] comment: Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%. synonym: "response to hypoxic stress" EXACT [] synonym: "response to intermittent hypoxia" NARROW [] synonym: "response to lowered oxygen tension" EXACT [] synonym: "response to sustained hypoxia" NARROW [] is_a: GO:0006950 ! response to stress is_a: GO:0036293 ! response to decreased oxygen levels [Term] id: GO:0001667 name: ameboidal-type cell migration def: "Cell migration that is accomplished by extension and retraction of a pseudopodium." [GOC:dph] comment: Note that this term refers to a mode of migration rather than to any particular cell type. synonym: "ameboid cell migration" EXACT [] synonym: "amoeboid cell migration" EXACT [] synonym: "amoeboidal cell migration" EXACT [] is_a: GO:0016477 ! cell migration property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0001669 name: acrosomal vesicle def: "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." [ISBN:0124325653, ISBN:0198506732] synonym: "acrosomal granule" EXACT [GOC:sart] synonym: "acrosome" EXACT [GOC:dph] xref: Wikipedia:Acrosome is_a: GO:0030141 ! secretory granule relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of CL:0000019 ! sperm property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0001673 name: male germ cell nucleus alt_id: GO:0043081 def: "The nucleus of a male germ cell, a reproductive cell in males." [CL:0000015, GOC:hjd, GOC:mtg_sensu] synonym: "male germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000015 ! male germ cell relationship: part_of CL:0000015 ! male germ cell [Term] id: GO:0001674 name: female germ cell nucleus alt_id: GO:0043080 def: "The nucleus of the female germ cell, a reproductive cell in females." [CL:0000021, GOC:hjd] synonym: "female germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000021 ! female germ cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of CL:0000021 ! female germ cell [Term] id: GO:0001675 name: acrosome assembly def: "The formation of the acrosome from the spermatid Golgi." [GOC:dph, GOC:hjd, GOC:tb] synonym: "acrosome formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0033363 ! secretory granule organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0001669 ! results in assembly of acrosomal vesicle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0007286 ! spermatid development relationship: RO:0002588 GO:0001669 ! results in assembly of acrosomal vesicle property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0001677 name: formation of translation initiation ternary complex def: "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:hjd] synonym: "translation initiation ternary complex assembly" EXACT [] is_a: GO:0022618 ! protein-RNA complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0044207 ! results in assembly of translation initiation ternary complex relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0006413 ! translational initiation relationship: RO:0002588 GO:0044207 ! results in assembly of translation initiation ternary complex [Term] id: GO:0001678 name: intracellular glucose homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of glucose within a cell." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "cell glucose homeostasis" EXACT [GOC:dph, GOC:tb] synonym: "cellular glucose homeostasis" EXACT [] is_a: GO:0042593 ! glucose homeostasis is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: RO:0002332 CHEBI:4167 ! regulates levels of D-glucopyranose [Term] id: GO:0001696 name: gastric acid secretion def: "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:hjd] synonym: "hydrochloric acid secretion" NARROW [] is_a: GO:0022600 ! digestive system process is_a: GO:0046717 ! acid secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0001700 name: embryonic development via the syncytial blastoderm def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: in_taxon NCBITaxon:50557 ! Insecta [Term] id: GO:0001701 name: in utero embryonic development def: "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0043009 ! chordate embryonic development relationship: in_taxon NCBITaxon:32525 ! Theria [Term] id: GO:0001702 name: gastrulation with mouth forming second alt_id: GO:0010003 alt_id: GO:0048276 def: "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second." [GOC:go_curators, GOC:mtg_sensu] synonym: "deuterostomic gastrulation" EXACT [GOC:dph] is_a: GO:0007369 ! gastrulation relationship: in_taxon NCBITaxon:33511 ! Deuterostomia [Term] id: GO:0001704 name: formation of primary germ layer def: "The formation of the ectoderm, mesoderm and endoderm during gastrulation." [GOC:go_curators] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000923 ! results in formation of anatomical entity germ layer relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007369 ! gastrulation relationship: RO:0002297 UBERON:0000923 ! results in formation of anatomical entity germ layer [Term] id: GO:0001705 name: ectoderm formation def: "The formation of ectoderm during gastrulation." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000924 ! results in formation of anatomical entity ectoderm relationship: part_of GO:0007398 ! ectoderm development relationship: RO:0002297 UBERON:0000924 ! results in formation of anatomical entity ectoderm [Term] id: GO:0001706 name: endoderm formation def: "The formation of the endoderm during gastrulation." [GOC:go_curators] synonym: "endoblast formation" NARROW [GOC:dph, GOC:sdb_2009, GOC:tb] xref: Reactome:R-HSA-9823730 "Formation of definitive endoderm" is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000925 ! results in formation of anatomical entity endoderm relationship: part_of GO:0007492 ! endoderm development relationship: RO:0002297 UBERON:0000925 ! results in formation of anatomical entity endoderm [Term] id: GO:0001707 name: mesoderm formation def: "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000926 ! results in formation of anatomical entity mesoderm relationship: part_of GO:0048332 ! mesoderm morphogenesis relationship: RO:0002297 UBERON:0000926 ! results in formation of anatomical entity mesoderm [Term] id: GO:0001743 name: lens placode formation def: "The initial developmental process that will lead to the formation of an eye." [GOC:dph] synonym: "optic placode formation" RELATED [] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003073 ! results in formation of anatomical entity lens placode relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048598 ! embryonic morphogenesis relationship: RO:0002297 UBERON:0003073 ! results in formation of anatomical entity lens placode [Term] id: GO:0001745 name: compound eye morphogenesis def: "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu] synonym: "insect-type retina morphogenesis" EXACT [PMID:11735386] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000018 ! results in morphogenesis of compound eye relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048749 ! compound eye development relationship: RO:0002298 UBERON:0000018 ! results in morphogenesis of compound eye [Term] id: GO:0001751 name: compound eye photoreceptor cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." [GOC:go_curators] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000019 ! results in acquisition of features of compound eye photoreceptor cell relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0001745 ! compound eye morphogenesis relationship: RO:0002315 CL:2000019 ! results in acquisition of features of compound eye photoreceptor cell [Term] id: GO:0001754 name: eye photoreceptor cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators] is_a: GO:0046530 ! photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000287 ! results in acquisition of features of eye photoreceptor cell relationship: part_of GO:0048592 ! eye morphogenesis relationship: RO:0002315 CL:0000287 ! results in acquisition of features of eye photoreceptor cell [Term] id: GO:0001755 name: neural crest cell migration def: "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." [GOC:ascb_2009, GOC:dph, GOC:tb, ISBN:0878932437] is_a: GO:0090497 ! mesenchymal cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000333 ! results in movement of migratory neural crest cell relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0014032 ! neural crest cell development relationship: RO:0002565 CL:0000333 ! results in movement of migratory neural crest cell [Term] id: GO:0001756 name: somitogenesis def: "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [ISBN:0721662544] synonym: "formation of mesodermal clusters" EXACT systematic_synonym [] xref: Reactome:R-HSA-9824272 "Somitogenesis" xref: Wikipedia:Somitogenesis is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0035282 ! segmentation is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002329 ! results in formation of anatomical entity somite relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0043009 ! chordate embryonic development relationship: part_of GO:0061053 ! somite development relationship: RO:0002297 UBERON:0002329 ! results in formation of anatomical entity somite [Term] id: GO:0001763 name: morphogenesis of a branching structure def: "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." [ISBN:0721662544] synonym: "branching morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis is_a: GO:0032501 ! multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0001764 name: neuron migration def: "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." [CL:0000540, GOC:go_curators] synonym: "neuron chemotaxis" EXACT [] synonym: "neuron guidance" RELATED [] synonym: "neuronal migration" EXACT [] xref: Wikipedia:Neural_development#Neuron_migration xref: Wikipedia:Neuron_migration is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000540 ! results in movement of neuron relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048699 ! generation of neurons relationship: RO:0002565 CL:0000540 ! results in movement of neuron [Term] id: GO:0001767 name: establishment of lymphocyte polarity def: "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "lymphocyte polarization" EXACT [] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000542 ! occurs in lymphocyte relationship: BFO:0000066 CL:0000542 ! occurs in lymphocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0046649 ! lymphocyte activation [Term] id: GO:0001768 name: establishment of T cell polarity def: "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "establishment of T lymphocyte polarity" EXACT [] synonym: "establishment of T-cell polarity" EXACT [] synonym: "establishment of T-lymphocyte polarity" EXACT [] synonym: "T cell polarization" EXACT [] synonym: "T lymphocyte polarization" EXACT [] synonym: "T-cell polarization" EXACT [] is_a: GO:0001767 ! establishment of lymphocyte polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell relationship: BFO:0000066 CL:0000084 ! occurs in T cell relationship: part_of GO:0042110 ! T cell activation [Term] id: GO:0001775 name: cell activation def: "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell." [GOC:mgi_curators] subset: goslim_pir is_a: GO:0009987 ! cellular process is_a: GO:0032501 ! multicellular organismal process relationship: in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24416" xsd:anyURI [Term] id: GO:0001776 name: leukocyte homeostasis def: "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, ISBN:0781735149] comment: Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus. synonym: "immune cell homeostasis" EXACT [] synonym: "leucocyte homeostasis" EXACT [] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000738 ! acts on population of leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0012003 CL:0000738 ! acts on population of leukocyte [Term] id: GO:0001777 name: T cell homeostatic proliferation def: "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." [GOC:mgi_curators, ISBN:0781735149] synonym: "resting T cell proliferation" EXACT [] synonym: "resting T-cell proliferation" EXACT [] synonym: "T lymphocyte homeostatic proliferation" EXACT [] synonym: "T-cell homeostatic proliferation" EXACT [] synonym: "T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0042592 ! homeostatic process intersection_of: RO:0012003 CL:0000084 ! acts on population of T cell relationship: part_of GO:0043029 ! T cell homeostasis [Term] id: GO:0001816 name: cytokine production alt_id: GO:0042032 alt_id: GO:0042089 alt_id: GO:0042107 alt_id: GO:0050663 def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "cytokine biosynthetic process" NARROW [] synonym: "cytokine metabolic process" NARROW [] synonym: "cytokine secretion" NARROW [] synonym: "interferon production" NARROW [GOC:add, GOC:mah] synonym: "interferon secretion" NARROW [GOC:add, GOC:mah] synonym: "interleukin production" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] synonym: "interleukin secretion" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] is_a: GO:0010467 ! gene expression is_a: GO:0032501 ! multicellular organismal process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19116" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0001817 name: regulation of cytokine production alt_id: GO:0042035 alt_id: GO:0050707 def: "Any process that modulates the frequency, rate, or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "regulation of cytokine anabolism" EXACT [] synonym: "regulation of cytokine biosynthesis" EXACT [] synonym: "regulation of cytokine biosynthetic process" NARROW [] synonym: "regulation of cytokine formation" EXACT [] synonym: "regulation of cytokine secretion" NARROW [] synonym: "regulation of cytokine synthesis" EXACT [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001816 ! regulates cytokine production relationship: RO:0002211 GO:0001816 ! regulates cytokine production property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0001818 name: negative regulation of cytokine production alt_id: GO:0042036 alt_id: GO:0050710 def: "Any process that stops, prevents, or reduces the rate of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "down regulation of cytokine biosynthetic process" EXACT [] synonym: "down regulation of cytokine production" EXACT [] synonym: "down-regulation of cytokine biosynthetic process" EXACT [] synonym: "down-regulation of cytokine production" EXACT [] synonym: "downregulation of cytokine biosynthetic process" EXACT [] synonym: "downregulation of cytokine production" EXACT [] synonym: "inhibition of cytokine biosynthetic process" NARROW [] synonym: "inhibition of cytokine production" NARROW [] synonym: "negative regulation of cytokine anabolism" EXACT [] synonym: "negative regulation of cytokine biosynthesis" EXACT [] synonym: "negative regulation of cytokine biosynthetic process" NARROW [] synonym: "negative regulation of cytokine formation" EXACT [] synonym: "negative regulation of cytokine secretion" NARROW [] synonym: "negative regulation of cytokine synthesis" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001816 ! negatively regulates cytokine production relationship: RO:0002212 GO:0001816 ! negatively regulates cytokine production property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0001819 name: positive regulation of cytokine production alt_id: GO:0042108 alt_id: GO:0050715 def: "Any process that activates or increases the frequency, rate or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "activation of cytokine production" NARROW [] synonym: "positive regulation of cytokine biosynthetic process" NARROW [] synonym: "positive regulation of cytokine secretion" NARROW [] synonym: "stimulation of cytokine production" NARROW [] synonym: "up regulation of cytokine production" EXACT [] synonym: "up-regulation of cytokine production" EXACT [] synonym: "upregulation of cytokine production" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001816 ! positively regulates cytokine production relationship: RO:0002213 GO:0001816 ! positively regulates cytokine production property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0001820 name: serotonin secretion def: "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." [GOC:ef, ISBN:0198506732, ISBN:0781735149] synonym: "5-HT secretion" EXACT [] synonym: "5-hydroxytryptamine secretion" EXACT [] synonym: "serotonin release" RELATED [GOC:tb] is_a: GO:0006837 ! serotonin transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0001822 name: kidney development def: "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10, ISBN:0124020607, ISBN:0721662544] synonym: "nephrogenesis" RELATED [GOC:rph] xref: Reactome:R-HSA-9830369 "Kidney development" xref: Wikipedia:Kidney_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002113 ! results in development of kidney relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072001 ! renal system development relationship: RO:0002296 UBERON:0002113 ! results in development of kidney [Term] id: GO:0001823 name: mesonephros development def: "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney." [GOC:dph, ISBN:0124020607, ISBN:0721662544, PMID:10535314] synonym: "Wolffian body development" EXACT [GOC:dph] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000080 ! results in development of mesonephros relationship: RO:0002296 UBERON:0000080 ! results in development of mesonephros [Term] id: GO:0001824 name: blastocyst development def: "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'. synonym: "blastula development" RELATED [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000358 ! results in development of blastocyst relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001701 ! in utero embryonic development relationship: RO:0002296 UBERON:0000358 ! results in development of blastocyst property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29162" xsd:anyURI [Term] id: GO:0001825 name: blastocyst formation def: "The initial formation of a blastocyst from a solid ball of cells known as a morula." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'. synonym: "blastula formation" RELATED [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000358 ! results in formation of anatomical entity blastocyst relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001824 ! blastocyst development relationship: RO:0002297 UBERON:0000358 ! results in formation of anatomical entity blastocyst property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29162" xsd:anyURI [Term] id: GO:0001826 name: inner cell mass cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'. is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000020 ! results in acquisition of features of inner cell mass cell relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001825 ! blastocyst formation relationship: RO:0002315 CL:2000020 ! results in acquisition of features of inner cell mass cell [Term] id: GO:0001829 name: trophectodermal cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'. synonym: "trophectoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000274 ! results in acquisition of features of trophectodermal cell relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001825 ! blastocyst formation relationship: RO:0002315 CL:1000274 ! results in acquisition of features of trophectodermal cell [Term] id: GO:0001831 name: trophectodermal cellular morphogenesis def: "The morphogenesis of trophectoderm cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. synonym: "trophectoderm cellular morphogenesis" EXACT [] is_a: GO:0000902 ! cell morphogenesis is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:1000274 ! results in morphogenesis of trophectodermal cell relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001829 ! trophectodermal cell differentiation relationship: RO:0002298 CL:1000274 ! results in morphogenesis of trophectodermal cell [Term] id: GO:0001832 name: blastocyst growth def: "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'. synonym: "blastula growth" RELATED [] is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 UBERON:0000358 ! results in growth of blastocyst relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001824 ! blastocyst development relationship: RO:0002343 UBERON:0000358 ! results in growth of blastocyst property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29162" xsd:anyURI [Term] id: GO:0001833 name: inner cell mass cell proliferation def: "The proliferation of cells in the inner cell mass." [GOC:dph, GOC:isa_complete, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'. is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:2000020 ! acts on population of inner cell mass cell relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001832 ! blastocyst growth relationship: RO:0012003 CL:2000020 ! acts on population of inner cell mass cell [Term] id: GO:0001834 name: trophectodermal cell proliferation def: "The proliferation of cells in the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. synonym: "trophectoderm cell proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:1000274 ! acts on population of trophectodermal cell relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001832 ! blastocyst growth relationship: RO:0012003 CL:1000274 ! acts on population of trophectodermal cell [Term] id: GO:0001837 name: epithelial to mesenchymal transition def: "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, PMID:14701881] synonym: "EMT" EXACT [] synonym: "epithelial-mesenchymal transition" EXACT [] synonym: "mesenchymal cell differentiation from epithelial cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] xref: Reactome:R-HSA-9758919 "Epithelial-Mesenchymal Transition (EMT) during gastrulation" is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008019 ! results in acquisition of features of mesenchymal cell intersection_of: RO:0004009 CL:0000066 ! has primary input epithelial cell relationship: RO:0004009 CL:0000066 ! has primary input epithelial cell [Term] id: GO:0001838 name: embryonic epithelial tube formation def: "The morphogenesis of an embryonic epithelium into a tube-shaped structure." [GOC:dph, ISBN:0824072820] is_a: GO:0072175 ! epithelial tube formation relationship: part_of GO:0016331 ! morphogenesis of embryonic epithelium [Term] id: GO:0001839 name: neural plate morphogenesis def: "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." [GOC:dph, ISBN:0878932437] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003075 ! results in morphogenesis of neural plate relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0001840 ! neural plate development relationship: RO:0002298 UBERON:0003075 ! results in morphogenesis of neural plate [Term] id: GO:0001840 name: neural plate development def: "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GOC:dph, GOC:ef, ISBN:0878932437, ISBN:0878932585] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003075 ! results in development of neural plate relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0043009 ! chordate embryonic development relationship: RO:0002296 UBERON:0003075 ! results in development of neural plate [Term] id: GO:0001841 name: neural tube formation alt_id: GO:0001679 def: "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GOC:dph, ISBN:0878932437] synonym: "neural tube morphogenesis" EXACT [GOC:dph] synonym: "neurulation" EXACT [] xref: Wikipedia:Neurulation is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001049 ! results in formation of anatomical entity neural tube relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021915 ! neural tube development relationship: RO:0002297 UBERON:0001049 ! results in formation of anatomical entity neural tube [Term] id: GO:0001842 name: neural fold formation def: "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." [GOC:dph, ISBN:0878932437] synonym: "neural groove formation" RELATED [GOC:dph] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005062 ! results in formation of anatomical entity neural fold relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0014020 ! primary neural tube formation relationship: RO:0002297 UBERON:0005062 ! results in formation of anatomical entity neural fold [Term] id: GO:0001885 name: endothelial cell development def: "The progression of an endothelial cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000115 ! results in development of endothelial cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0045446 ! endothelial cell differentiation relationship: RO:0002296 CL:0000115 ! results in development of endothelial cell [Term] id: GO:0001886 name: endothelial cell morphogenesis def: "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000115 ! results in morphogenesis of endothelial cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001885 ! endothelial cell development relationship: RO:0002298 CL:0000115 ! results in morphogenesis of endothelial cell [Term] id: GO:0001889 name: liver development def: "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes." [GOC:add, ISBN:068340007X] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002107 ! results in development of liver relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: RO:0002296 UBERON:0002107 ! results in development of liver [Term] id: GO:0001890 name: placenta development def: "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "placental development" EXACT [] synonym: "placentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001987 ! results in development of placenta relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002296 UBERON:0001987 ! results in development of placenta [Term] id: GO:0001892 name: embryonic placenta development def: "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "fetal placenta development" EXACT [GOC:dph] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007106 ! results in development of chorionic villus relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001701 ! in utero embryonic development relationship: part_of GO:0001890 ! placenta development relationship: RO:0002296 UBERON:0007106 ! results in development of chorionic villus [Term] id: GO:0001893 name: maternal placenta development def: "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "decidua development" RELATED [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development is_a: GO:0060135 ! maternal process involved in female pregnancy intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002450 ! results in development of decidua relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001890 ! placenta development relationship: RO:0002296 UBERON:0002450 ! results in development of decidua [Term] id: GO:0001935 name: endothelial cell proliferation def: "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [GOC:add, ISBN:0781735149] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000115 ! acts on population of endothelial cell relationship: RO:0012003 CL:0000115 ! acts on population of endothelial cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0001936 name: regulation of endothelial cell proliferation def: "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." [GOC:add] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001935 ! regulates endothelial cell proliferation relationship: RO:0002211 GO:0001935 ! regulates endothelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0001937 name: negative regulation of endothelial cell proliferation def: "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "down regulation of endothelial cell proliferation" EXACT [] synonym: "down-regulation of endothelial cell proliferation" EXACT [] synonym: "downregulation of endothelial cell proliferation" EXACT [] synonym: "inhibition of endothelial cell proliferation" NARROW [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050680 ! negative regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001935 ! negatively regulates endothelial cell proliferation relationship: RO:0002212 GO:0001935 ! negatively regulates endothelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0001938 name: positive regulation of endothelial cell proliferation def: "Any process that activates or increases the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "activation of endothelial cell proliferation" NARROW [] synonym: "stimulation of endothelial cell proliferation" NARROW [] synonym: "up regulation of endothelial cell proliferation" EXACT [] synonym: "up-regulation of endothelial cell proliferation" EXACT [] synonym: "upregulation of endothelial cell proliferation" EXACT [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050679 ! positive regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001935 ! positively regulates endothelial cell proliferation relationship: RO:0002213 GO:0001935 ! positively regulates endothelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0001940 name: male pronucleus def: "The pronucleus originating from the spermatozoa that was involved in fertilization." [GOC:hjd, ISBN:0198506732] is_a: GO:0045120 ! pronucleus [Term] id: GO:0001942 name: hair follicle development namespace: biological_process alt_id: GO:0001943 def: "The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open." [GOC:dph, UBERON:0002073] is_a: GO:0022405 ! hair cycle process is_a: GO:0048856 ! anatomical structure development relationship: part_of GO:0098773 ! skin epidermis development [Term] id: GO:0001944 name: vasculature development def: "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." [GOC:dph, UBERON:0002409] synonym: "vascular system development" RELATED [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002049 ! results in development of vasculature relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0072359 ! circulatory system development relationship: RO:0002296 UBERON:0002049 ! results in development of vasculature [Term] id: GO:0001955 name: blood vessel maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001981 ! results in maturation of blood vessel relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001568 ! blood vessel development relationship: RO:0002299 UBERON:0001981 ! results in maturation of blood vessel [Term] id: GO:0001956 name: positive regulation of neurotransmitter secretion def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:hjd] synonym: "activation of neurotransmitter secretion" NARROW [] synonym: "stimulation of neurotransmitter secretion" NARROW [] synonym: "up regulation of neurotransmitter secretion" EXACT [] synonym: "up-regulation of neurotransmitter secretion" EXACT [] synonym: "upregulation of neurotransmitter secretion" EXACT [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:0051590 ! positive regulation of neurotransmitter transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007269 ! positively regulates neurotransmitter secretion relationship: RO:0002213 GO:0007269 ! positively regulates neurotransmitter secretion [Term] id: GO:0001957 name: intramembranous ossification def: "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." [ISBN:0878932437] comment: An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division. synonym: "dermal ossification" NARROW [GO_REF:0000034] synonym: "intramembranous bone ossification" RELATED [GOC:cjm] xref: Wikipedia:Intramembranous_ossification is_a: GO:0036072 ! direct ossification [Term] id: GO:0002009 name: morphogenesis of an epithelium def: "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph, GOC:jl, GOC:tb, ISBN:0198506732] synonym: "epithelium morphogenesis" EXACT [] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000483 ! results in morphogenesis of epithelium relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0060429 ! epithelium development relationship: RO:0002298 UBERON:0000483 ! results in morphogenesis of epithelium [Term] id: GO:0002011 name: morphogenesis of an epithelial sheet def: "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0010136 ! results in morphogenesis of epithelial sheet relationship: RO:0002298 UBERON:0010136 ! results in morphogenesis of epithelial sheet [Term] id: GO:0002027 name: regulation of heart rate def: "Any process that modulates the frequency or rate of heart contraction." [GOC:dph, GOC:tb, PMID:10358008] synonym: "cardiac chronotropy" EXACT [GOC:dph, GOC:tb] synonym: "regulation of heart contraction rate" EXACT [] synonym: "regulation of rate of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:0065008 ! regulation of biological quality property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002028 name: regulation of sodium ion transport def: "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph] synonym: "regulation of Na+ transport" EXACT [] synonym: "regulation of sodium transport" EXACT [] is_a: GO:0010959 ! regulation of metal ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006814 ! regulates sodium ion transport relationship: RO:0002211 GO:0006814 ! regulates sodium ion transport [Term] id: GO:0002052 name: positive regulation of neuroblast proliferation def: "Any process that activates or increases the rate of neuroblast proliferation." [GOC:dph] synonym: "activation of neuroblast proliferation" NARROW [] synonym: "stimulation of neuroblast proliferation" NARROW [] synonym: "up regulation of neuroblast proliferation" EXACT [] synonym: "up-regulation of neuroblast proliferation" EXACT [] synonym: "upregulation of neuroblast proliferation" EXACT [] is_a: GO:0050769 ! positive regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007405 ! positively regulates neuroblast proliferation relationship: RO:0002213 GO:0007405 ! positively regulates neuroblast proliferation [Term] id: GO:0002053 name: positive regulation of mesenchymal cell proliferation def: "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." [GOC:dph] synonym: "activation of mesenchymal cell proliferation" NARROW [] synonym: "stimulation of mesenchymal cell proliferation" NARROW [] synonym: "up regulation of mesenchymal cell proliferation" EXACT [] synonym: "up-regulation of mesenchymal cell proliferation" EXACT [] synonym: "upregulation of mesenchymal cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010463 ! positively regulates mesenchymal cell proliferation relationship: RO:0002213 GO:0010463 ! positively regulates mesenchymal cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0002062 name: chondrocyte differentiation def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000138 ! results in acquisition of features of chondrocyte relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0051216 ! cartilage development relationship: RO:0002315 CL:0000138 ! results in acquisition of features of chondrocyte [Term] id: GO:0002063 name: chondrocyte development def: "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000138 ! results in development of chondrocyte relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0002062 ! chondrocyte differentiation relationship: RO:0002296 CL:0000138 ! results in development of chondrocyte [Term] id: GO:0002064 name: epithelial cell development def: "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000066 ! results in development of epithelial cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0030855 ! epithelial cell differentiation relationship: RO:0002296 CL:0000066 ! results in development of epithelial cell [Term] id: GO:0002065 name: columnar/cuboidal epithelial cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000075 ! results in acquisition of features of columnar/cuboidal epithelial cell relationship: RO:0002315 CL:0000075 ! results in acquisition of features of columnar/cuboidal epithelial cell [Term] id: GO:0002066 name: columnar/cuboidal epithelial cell development def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000075 ! results in development of columnar/cuboidal epithelial cell relationship: part_of GO:0002065 ! columnar/cuboidal epithelial cell differentiation relationship: RO:0002296 CL:0000075 ! results in development of columnar/cuboidal epithelial cell [Term] id: GO:0002067 name: glandular epithelial cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000150 ! results in acquisition of features of glandular secretory epithelial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002315 CL:0000150 ! results in acquisition of features of glandular secretory epithelial cell [Term] id: GO:0002068 name: glandular epithelial cell development def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000150 ! results in development of glandular secretory epithelial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0002067 ! glandular epithelial cell differentiation relationship: RO:0002296 CL:0000150 ! results in development of glandular secretory epithelial cell [Term] id: GO:0002069 name: columnar/cuboidal epithelial cell maturation def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002070 ! epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000075 ! results in maturation of columnar/cuboidal epithelial cell relationship: part_of GO:0002066 ! columnar/cuboidal epithelial cell development relationship: RO:0002299 CL:0000075 ! results in maturation of columnar/cuboidal epithelial cell [Term] id: GO:0002070 name: epithelial cell maturation def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000066 ! results in maturation of epithelial cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0002064 ! epithelial cell development relationship: RO:0002299 CL:0000066 ! results in maturation of epithelial cell [Term] id: GO:0002071 name: glandular epithelial cell maturation def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000150 ! results in maturation of glandular secretory epithelial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0002068 ! glandular epithelial cell development relationship: RO:0002299 CL:0000150 ! results in maturation of glandular secretory epithelial cell [Term] id: GO:0002072 name: optic cup morphogenesis involved in camera-type eye development def: "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb, ISBN:0878932437] synonym: "optic cup morphogenesis involved in camera-style eye development" EXACT [] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003072 ! results in morphogenesis of optic cup relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060900 ! embryonic camera-type eye formation relationship: RO:0002298 UBERON:0003072 ! results in morphogenesis of optic cup [Term] id: GO:0002080 name: acrosomal membrane def: "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." [GOC:dph] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0001669 ! acrosomal vesicle relationship: bounding_layer_of GO:0001669 ! acrosomal vesicle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0001669 ! acrosomal vesicle property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0002085 name: inhibition of neuroepithelial cell differentiation def: "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, PMID:16678814] synonym: "negative regulation of neural plate formation" NARROW [GOC:dph, GOC:tb] synonym: "repression of premature neural plate formation" NARROW [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0048505 ! regulation of timing of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060563 ! negatively regulates neuroepithelial cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002212 GO:0060563 ! negatively regulates neuroepithelial cell differentiation [Term] id: GO:0002087 name: regulation of respiratory gaseous exchange by nervous system process def: "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." [GOC:dph, GOC:tb, PMID:12458206] synonym: "neurological control of breathing" EXACT [GOC:dph, GOC:tb] synonym: "regulation of respiratory gaseous exchange by neurological system process" EXACT [] is_a: GO:0044065 ! regulation of respiratory system process is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: RO:0002211 GO:0007585 ! regulates respiratory gaseous exchange by respiratory system [Term] id: GO:0002088 name: lens development in camera-type eye def: "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, ISBN:0582064333] synonym: "lens development" EXACT [] synonym: "lens development in camera-style eye" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000965 ! results in development of lens of camera-type eye relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0043010 ! camera-type eye development relationship: RO:0002296 UBERON:0000965 ! results in development of lens of camera-type eye [Term] id: GO:0002089 name: lens morphogenesis in camera-type eye def: "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu] synonym: "lens morphogenesis" EXACT [] synonym: "lens morphogenesis in camera-style eye" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000965 ! results in morphogenesis of lens of camera-type eye relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0002088 ! lens development in camera-type eye relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: RO:0002298 UBERON:0000965 ! results in morphogenesis of lens of camera-type eye [Term] id: GO:0002117 name: amphibian larval development def: "The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form." [GOC:bf, PMID:27143402] is_a: GO:0002164 ! larval development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002119 name: nematode larval development def: "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:ems, GOC:kmv] is_a: GO:0002164 ! larval development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009850 ! results in development of nematode larva relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0009850 ! results in development of nematode larva [Term] id: GO:0002164 name: larval development def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [GOC:jid, ISBN:0877795088] is_a: GO:0007275 ! multicellular organism development is_a: GO:0009791 ! post-embryonic development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002176 name: male germ cell proliferation def: "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population." [GOC:hjd] is_a: GO:0036093 ! germ cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000015 ! acts on population of male germ cell relationship: RO:0012003 CL:0000015 ! acts on population of male germ cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: hjd creation_date: 2010-11-18T02:35:14Z [Term] id: GO:0002181 name: cytoplasmic translation def: "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein." [GOC:hjd] comment: Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms. subset: goslim_generic subset: goslim_pombe subset: goslim_yeast is_a: GO:0006412 ! translation intersection_of: GO:0006412 ! translation intersection_of: RO:0002608 GO:0022626 ! process has causal agent cytosolic ribosome relationship: RO:0002608 GO:0022626 ! process has causal agent cytosolic ribosome created_by: hjd creation_date: 2011-06-09T03:11:53Z [Term] id: GO:0002182 name: cytoplasmic translational elongation def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm." [GOC:hjd] is_a: GO:0006414 ! translational elongation intersection_of: GO:0006414 ! translational elongation intersection_of: part_of GO:0002181 ! cytoplasmic translation relationship: part_of GO:0002181 ! cytoplasmic translation created_by: hjd creation_date: 2011-06-09T03:14:42Z [Term] id: GO:0002183 name: cytoplasmic translational initiation def: "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [GOC:hjd] is_a: GO:0006413 ! translational initiation intersection_of: GO:0006413 ! translational initiation intersection_of: part_of GO:0002181 ! cytoplasmic translation relationship: part_of GO:0002181 ! cytoplasmic translation created_by: hjd creation_date: 2011-06-09T03:15:48Z [Term] id: GO:0002184 name: cytoplasmic translational termination def: "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon." [GOC:hjd] is_a: GO:0006415 ! translational termination intersection_of: GO:0006415 ! translational termination intersection_of: BFO:0000066 GO:0005829 ! occurs in cytosol relationship: BFO:0000066 GO:0005829 ! occurs in cytosol relationship: part_of GO:0002181 ! cytoplasmic translation created_by: hjd creation_date: 2011-06-09T03:17:13Z [Term] id: GO:0002213 name: defense response to insect alt_id: GO:0002214 def: "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." [GOC:add] synonym: "physiological defense response to insect" EXACT [] is_a: GO:0006952 ! defense response is_a: GO:0051707 ! response to other organism intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon:50557 ! has primary input Insecta relationship: RO:0004009 NCBITaxon:50557 ! has primary input Insecta property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002215 name: defense response to nematode alt_id: GO:0002216 def: "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:add, PMID:11516579, PMID:14506883] synonym: "physiological defense response to nematode" EXACT [] is_a: GO:0006952 ! defense response is_a: GO:0051707 ! response to other organism intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon:6231 ! has primary input Nematoda relationship: RO:0004009 NCBITaxon:6231 ! has primary input Nematoda property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002244 name: hematopoietic progenitor cell differentiation def: "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251] synonym: "haematopoietic progenitor cell differentiation" EXACT [] synonym: "haemopoietic progenitor cell differentiation" EXACT [] synonym: "hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008001 ! results in acquisition of features of hematopoietic precursor cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0030097 ! hemopoiesis relationship: RO:0002315 CL:0008001 ! results in acquisition of features of hematopoietic precursor cell [Term] id: GO:0002250 name: adaptive immune response def: "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "acquired immune response" EXACT [ISBN:068340007X] synonym: "immune memory response" EXACT [GOC:add] xref: Reactome:R-HSA-1280218 "Adaptive Immune System" xref: Wikipedia:Adaptive_immune_system is_a: GO:0006955 ! immune response relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0002251 name: organ or tissue specific immune response def: "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." [GO_REF:0000022, GOC:jal] synonym: "immune response in organ or tissue" EXACT [] is_a: GO:0006955 ! immune response property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002252 name: immune effector process def: "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0002376 ! immune system process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18737" xsd:anyURI property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002260 name: lymphocyte homeostasis def: "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:15826826, PMID:16319493, PMID:16551252, PMID:16551262] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000542 ! acts on population of lymphocyte relationship: RO:0012003 CL:0000542 ! acts on population of lymphocyte [Term] id: GO:0002262 name: myeloid cell homeostasis def: "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000763, GOC:add] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000763 ! acts on population of myeloid cell relationship: RO:0012003 CL:0000763 ! acts on population of myeloid cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002263 name: cell activation involved in immune response def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell activation during immune response" RELATED [GOC:tb] is_a: GO:0001775 ! cell activation is_a: GO:0002252 ! immune effector process intersection_of: GO:0001775 ! cell activation intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002264 name: endothelial cell activation involved in immune response def: "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "endothelial cell activation during immune response" RELATED [GOC:tb] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0042118 ! endothelial cell activation intersection_of: GO:0042118 ! endothelial cell activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002269 name: leukocyte activation involved in inflammatory response def: "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." [GOC:add, ISBN:0781735149] synonym: "immune cell activation during inflammatory response" RELATED [] synonym: "leukocyte activation during inflammatory response" RELATED [GOC:tb] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002274 name: myeloid leukocyte activation def: "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte activation" EXACT [] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000766 ! has primary input myeloid leukocyte relationship: RO:0004009 CL:0000766 ! has primary input myeloid leukocyte [Term] id: GO:0002285 name: lymphocyte activation involved in immune response def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "lymphocyte activation during immune response" RELATED [GOC:tb] is_a: GO:0002366 ! leukocyte activation involved in immune response is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0046649 ! lymphocyte activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002286 name: T cell activation involved in immune response def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "T cell activation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte activation during immune response" RELATED [] synonym: "T-cell activation during immune response" RELATED [] synonym: "T-lymphocyte activation during immune response" RELATED [] is_a: GO:0002285 ! lymphocyte activation involved in immune response is_a: GO:0042110 ! T cell activation intersection_of: GO:0042110 ! T cell activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002292 name: T cell differentiation involved in immune response def: "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "T cell development involved in immune response" RELATED [GOC:add] synonym: "T cell differentiation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte differentiation during immune response" RELATED [] synonym: "T-cell differentiation during immune response" RELATED [] synonym: "T-lymphocyte differentiation during immune response" RELATED [] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0030217 ! T cell differentiation intersection_of: GO:0030217 ! T cell differentiation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002309 name: T cell proliferation involved in immune response def: "The expansion of a T cell population by cell division as part of an immune response." [GOC:add, ISBN:0781735149] synonym: "T cell proliferation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte proliferation during immune response" RELATED [] synonym: "T-cell proliferation during immune response" RELATED [] synonym: "T-lymphocyte proliferation during immune response" RELATED [] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0042098 ! T cell proliferation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002318 name: myeloid progenitor cell differentiation def: "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." [GOC:add, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000839 ! results in acquisition of features of myeloid lineage restricted progenitor cell relationship: RO:0002315 CL:0000839 ! results in acquisition of features of myeloid lineage restricted progenitor cell [Term] id: GO:0002320 name: lymphoid progenitor cell differentiation def: "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." [GOC:add, PMID:16551251, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000838 ! results in acquisition of features of lymphoid lineage restricted progenitor cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002315 CL:0000838 ! results in acquisition of features of lymphoid lineage restricted progenitor cell [Term] id: GO:0002351 name: serotonin production involved in inflammatory response def: "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260] synonym: "serotonin production involved in acute inflammatory response" BROAD [] is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response [Term] id: GO:0002366 name: leukocyte activation involved in immune response def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "immune cell activation during immune response" RELATED [] synonym: "leucocyte activation during immune response" RELATED [] synonym: "leukocyte activation during immune response" RELATED [GOC:tb] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002367 name: cytokine production involved in immune response alt_id: GO:0002374 alt_id: GO:0002375 def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "cytokine biosynthetic process involved in immune response" NARROW [] synonym: "cytokine production during immune response" RELATED [GOC:dph] synonym: "cytokine secretion during immune response" RELATED [GOC:dph] synonym: "cytokine secretion involved in immune response" RELATED [] is_a: GO:0001816 ! cytokine production is_a: GO:0002440 ! production of molecular mediator of immune response intersection_of: GO:0001816 ! cytokine production intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002369 name: T cell cytokine production def: "Any process that contributes to cytokine production by a T cell." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "T lymphocyte cytokine production" EXACT [] synonym: "T-cell cytokine production" EXACT [] synonym: "T-lymphocyte cytokine production" EXACT [] is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002456 ! T cell mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: RO:0002608 CL:0000084 ! process has causal agent T cell [Term] id: GO:0002371 name: dendritic cell cytokine production def: "Any process that contributes to cytokine production by a dendritic cell." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: RO:0002608 CL:0000451 ! process has causal agent dendritic cell relationship: RO:0002608 CL:0000451 ! process has causal agent dendritic cell [Term] id: GO:0002376 name: immune system process def: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add] comment: Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501). subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir xref: Wikipedia:Immune_system is_a: GO:0008150 ! biological process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002384 name: hepatic immune response def: "An immune response taking place in the liver." [GO_REF:0000022, GOC:jal, ISBN:0781735149] is_a: GO:0002251 ! organ or tissue specific immune response intersection_of: GO:0006955 ! immune response intersection_of: BFO:0000066 UBERON:0002107 ! occurs in liver relationship: BFO:0000066 UBERON:0002107 ! occurs in liver relationship: in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0002396 name: MHC protein complex assembly def: "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] is_a: GO:0065003 ! protein-containing complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042611 ! results in assembly of MHC protein complex relationship: RO:0002588 GO:0042611 ! results in assembly of MHC protein complex [Term] id: GO:0002399 name: MHC class II protein complex assembly def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0002396 ! MHC protein complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042613 ! results in assembly of MHC class II protein complex relationship: RO:0002588 GO:0042613 ! results in assembly of MHC class II protein complex [Term] id: GO:0002440 name: production of molecular mediator of immune response def: "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "production of cellular mediator of immune response" RELATED [] is_a: GO:0002376 ! immune system process is_a: GO:0010467 ! gene expression property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002442 name: serotonin secretion involved in inflammatory response def: "The regulated release of serotonin by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149] synonym: "serotonin release involved in inflammatory response" RELATED [GOC:tb] synonym: "serotonin secretion involved in acute inflammatory response" BROAD [] is_a: GO:0001820 ! serotonin secretion intersection_of: GO:0001820 ! serotonin secretion intersection_of: part_of GO:0006954 ! inflammatory response relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0002351 ! serotonin production involved in inflammatory response [Term] id: GO:0002443 name: leukocyte mediated immunity alt_id: GO:0019723 alt_id: GO:0042087 def: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immune response" RELATED [] synonym: "cellular immune response" RELATED [] synonym: "immune cell effector process" EXACT [] synonym: "immune cell mediated immunity" EXACT [] synonym: "leucocyte immune effector process" EXACT [] synonym: "leucocyte mediated immunity" EXACT [] synonym: "leukocyte immune effector process" EXACT [] is_a: GO:0002252 ! immune effector process intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000738 ! process has causal agent leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002608 CL:0000738 ! process has causal agent leukocyte [Term] id: GO:0002444 name: myeloid leukocyte mediated immunity def: "Any process involved in the carrying out of an immune response by a myeloid leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte immune effector process" EXACT [] synonym: "myeloid leucocyte mediated immunity" EXACT [] synonym: "myeloid leukocyte immune effector process" EXACT [] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000766 ! process has causal agent myeloid leukocyte relationship: RO:0002608 CL:0000766 ! process has causal agent myeloid leukocyte [Term] id: GO:0002449 name: lymphocyte mediated immunity def: "Any process involved in the carrying out of an immune response by a lymphocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immunity" BROAD [] synonym: "cellular immune response" BROAD [] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000542 ! process has causal agent lymphocyte relationship: RO:0002608 CL:0000542 ! process has causal agent lymphocyte [Term] id: GO:0002456 name: T cell mediated immunity def: "Any process involved in the carrying out of an immune response by a T cell." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immunity" BROAD [] synonym: "cellular immune response" BROAD [] synonym: "T lymphocyte mediated immunity" EXACT [] synonym: "T-cell mediated immunity" EXACT [] synonym: "T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002449 ! lymphocyte mediated immunity is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0002376 ! immune system process intersection_of: RO:0002608 CL:0000084 ! process has causal agent T cell relationship: RO:0002608 CL:0000084 ! process has causal agent T cell [Term] id: GO:0002457 name: T cell antigen processing and presentation def: "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, PMID:11417857, PMID:15120183] synonym: "T lymphocyte antigen processing and presentation" EXACT [] synonym: "T-cell antigen processing and presentation" EXACT [] synonym: "T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell relationship: BFO:0000066 CL:0000084 ! occurs in T cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0002456 ! T cell mediated immunity [Term] id: GO:0002460 name: adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains def: "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149, ISBN:1405196831] is_a: GO:0002250 ! adaptive immune response [Term] id: GO:0002468 name: dendritic cell antigen processing and presentation def: "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: BFO:0000066 CL:0000451 ! occurs in dendritic cell relationship: BFO:0000066 CL:0000451 ! occurs in dendritic cell property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002504 name: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II def: "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15531770, PMID:15771591, PMID:16153240] synonym: "peptide or polysaccharide antigen processing and presentation of via MHC class II" EXACT [] is_a: GO:0019882 ! antigen processing and presentation property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002520 name: immune system development def: "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:add, GOC:dph] subset: goslim_drosophila is_a: GO:0002376 ! immune system process is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002405 ! results in development of immune system relationship: RO:0002296 UBERON:0002405 ! results in development of immune system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002521 name: leukocyte differentiation def: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:add, PMID:16551264] synonym: "immune cell differentiation" EXACT [] synonym: "leucocyte differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000738 ! results in acquisition of features of leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030097 ! hemopoiesis relationship: RO:0002315 CL:0000738 ! results in acquisition of features of leukocyte [Term] id: GO:0002522 name: leukocyte migration involved in immune response def: "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration during immune response" EXACT [] synonym: "immune cell trafficking during immune response" EXACT [] synonym: "leucocyte migration during immune response" EXACT [] synonym: "leucocyte trafficking during immune response" EXACT [] synonym: "leukocyte trafficking during immune response" EXACT [] is_a: GO:0002252 ! immune effector process is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002523 name: leukocyte migration involved in inflammatory response def: "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration during inflammatory response" RELATED [] synonym: "immune cell trafficking during inflammatory response" RELATED [] synonym: "leucocyte migration during inflammatory response" RELATED [] synonym: "leucocyte trafficking during inflammatory response" RELATED [] synonym: "leukocyte migration during inflammatory response" RELATED [GOC:dph] synonym: "leukocyte trafficking during inflammatory response" RELATED [] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002532 name: production of molecular mediator involved in inflammatory response def: "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] synonym: "production of cellular mediator of acute inflammation" RELATED [] synonym: "production of molecular mediator involved in acute inflammatory response" BROAD [] is_a: GO:0032501 ! multicellular organismal process relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002534 name: cytokine production involved in inflammatory response def: "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] subset: gocheck_do_not_annotate synonym: "cytokine production involved in acute inflammatory response" BROAD [] is_a: GO:0001816 ! cytokine production is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response intersection_of: GO:0001816 ! cytokine production intersection_of: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002572 name: pro-T cell differentiation def: "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." [GOC:add, ISBN:0781735149] synonym: "pro-T lymphocyte differentiation" EXACT [] is_a: GO:0002320 ! lymphoid progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000827 ! results in acquisition of features of pro-T cell relationship: part_of GO:0030217 ! T cell differentiation relationship: RO:0002315 CL:0000827 ! results in acquisition of features of pro-T cell [Term] id: GO:0002573 name: myeloid leukocyte differentiation def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." [GOC:add, PMID:16551251] synonym: "myeloid leucocyte differentiation" EXACT [] is_a: GO:0002521 ! leukocyte differentiation is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000766 ! results in acquisition of features of myeloid leukocyte relationship: RO:0002315 CL:0000766 ! results in acquisition of features of myeloid leukocyte [Term] id: GO:0002577 name: regulation of antigen processing and presentation def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019882 ! regulates antigen processing and presentation relationship: RO:0002211 GO:0019882 ! regulates antigen processing and presentation property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002578 name: negative regulation of antigen processing and presentation def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "down regulation of antigen processing and presentation" EXACT [] synonym: "down-regulation of antigen processing and presentation" EXACT [] synonym: "downregulation of antigen processing and presentation" EXACT [] synonym: "inhibition of antigen processing and presentation" NARROW [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002683 ! negative regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019882 ! negatively regulates antigen processing and presentation relationship: RO:0002212 GO:0019882 ! negatively regulates antigen processing and presentation property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002579 name: positive regulation of antigen processing and presentation def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "activation of antigen processing and presentation" NARROW [] synonym: "stimulation of antigen processing and presentation" NARROW [] synonym: "up regulation of antigen processing and presentation" EXACT [] synonym: "up-regulation of antigen processing and presentation" EXACT [] synonym: "upregulation of antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002684 ! positive regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019882 ! positively regulates antigen processing and presentation relationship: RO:0002213 GO:0019882 ! positively regulates antigen processing and presentation property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002580 name: regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002504 ! regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: RO:0002211 GO:0002504 ! regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002581 name: negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002504 ! negatively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: RO:0002212 GO:0002504 ! negatively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002582 name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] synonym: "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002504 ! positively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: RO:0002213 GO:0002504 ! positively regulates antigen processing and presentation of peptide or polysaccharide antigen via MHC class II property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002604 name: regulation of dendritic cell antigen processing and presentation def: "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002468 ! regulates dendritic cell antigen processing and presentation relationship: RO:0002211 GO:0002468 ! regulates dendritic cell antigen processing and presentation property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002605 name: negative regulation of dendritic cell antigen processing and presentation def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "down regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "down-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "downregulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "inhibition of dendritic cell antigen processing and presentation" NARROW [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002468 ! negatively regulates dendritic cell antigen processing and presentation relationship: RO:0002212 GO:0002468 ! negatively regulates dendritic cell antigen processing and presentation property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002606 name: positive regulation of dendritic cell antigen processing and presentation def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "activation of dendritic cell antigen processing and presentation" NARROW [] synonym: "stimulation of dendritic cell antigen processing and presentation" NARROW [] synonym: "up regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "up-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "upregulation of dendritic cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002468 ! positively regulates dendritic cell antigen processing and presentation relationship: RO:0002213 GO:0002468 ! positively regulates dendritic cell antigen processing and presentation property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002625 name: regulation of T cell antigen processing and presentation def: "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "regulation of T-cell antigen processing and presentation" EXACT [] synonym: "regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002709 ! regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002457 ! regulates T cell antigen processing and presentation relationship: RO:0002211 GO:0002457 ! regulates T cell antigen processing and presentation [Term] id: GO:0002626 name: negative regulation of T cell antigen processing and presentation def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "down regulation of T cell antigen processing and presentation" EXACT [] synonym: "down-regulation of T cell antigen processing and presentation" EXACT [] synonym: "downregulation of T cell antigen processing and presentation" EXACT [] synonym: "inhibition of T cell antigen processing and presentation" NARROW [] synonym: "negative regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "negative regulation of T-cell antigen processing and presentation" EXACT [] synonym: "negative regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002710 ! negative regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002457 ! negatively regulates T cell antigen processing and presentation relationship: RO:0002212 GO:0002457 ! negatively regulates T cell antigen processing and presentation [Term] id: GO:0002627 name: positive regulation of T cell antigen processing and presentation def: "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "activation of T cell antigen processing and presentation" NARROW [] synonym: "positive regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "positive regulation of T-cell antigen processing and presentation" EXACT [] synonym: "positive regulation of T-lymphocyte antigen processing and presentation" EXACT [] synonym: "stimulation of T cell antigen processing and presentation" NARROW [] synonym: "up regulation of T cell antigen processing and presentation" EXACT [] synonym: "up-regulation of T cell antigen processing and presentation" EXACT [] synonym: "upregulation of T cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002711 ! positive regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002457 ! positively regulates T cell antigen processing and presentation relationship: RO:0002213 GO:0002457 ! positively regulates T cell antigen processing and presentation [Term] id: GO:0002682 name: regulation of immune system process def: "Any process that modulates the frequency, rate, or extent of an immune system process." [GOC:add] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002376 ! regulates immune system process relationship: RO:0002211 GO:0002376 ! regulates immune system process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002683 name: negative regulation of immune system process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "down regulation of immune system process" EXACT [] synonym: "down-regulation of immune system process" EXACT [] synonym: "downregulation of immune system process" EXACT [] synonym: "inhibition of immune system process" NARROW [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002376 ! negatively regulates immune system process relationship: RO:0002212 GO:0002376 ! negatively regulates immune system process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002684 name: positive regulation of immune system process def: "Any process that activates or increases the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "activation of immune system process" NARROW [] synonym: "stimulation of immune system process" NARROW [] synonym: "up regulation of immune system process" EXACT [] synonym: "up-regulation of immune system process" EXACT [] synonym: "upregulation of immune system process" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002376 ! positively regulates immune system process relationship: RO:0002213 GO:0002376 ! positively regulates immune system process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002685 name: regulation of leukocyte migration def: "Any process that modulates the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "regulation of immune cell migration" EXACT [] synonym: "regulation of leucocyte migration" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050900 ! regulates leukocyte migration relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0050900 ! regulates leukocyte migration [Term] id: GO:0002686 name: negative regulation of leukocyte migration def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "down regulation of leukocyte migration" EXACT [] synonym: "down-regulation of leukocyte migration" EXACT [] synonym: "downregulation of leukocyte migration" EXACT [] synonym: "inhibition of leukocyte migration" NARROW [] synonym: "negative regulation of immune cell migration" EXACT [] synonym: "negative regulation of leucocyte migration" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050900 ! negatively regulates leukocyte migration relationship: RO:0002212 GO:0050900 ! negatively regulates leukocyte migration [Term] id: GO:0002687 name: positive regulation of leukocyte migration def: "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "activation of leukocyte migration" NARROW [] synonym: "positive regulation of immune cell migration" EXACT [] synonym: "positive regulation of leucocyte migration" EXACT [] synonym: "stimulation of leukocyte migration" NARROW [] synonym: "up regulation of leukocyte migration" EXACT [] synonym: "up-regulation of leukocyte migration" EXACT [] synonym: "upregulation of leukocyte migration" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050900 ! positively regulates leukocyte migration relationship: RO:0002213 GO:0050900 ! positively regulates leukocyte migration [Term] id: GO:0002694 name: regulation of leukocyte activation def: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "regulation of immune cell activation" EXACT [] synonym: "regulation of leucocyte activation" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045321 ! regulates leukocyte activation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0045321 ! regulates leukocyte activation [Term] id: GO:0002695 name: negative regulation of leukocyte activation def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "down regulation of leukocyte activation" EXACT [] synonym: "down-regulation of leukocyte activation" EXACT [] synonym: "downregulation of leukocyte activation" EXACT [] synonym: "inhibition of leukocyte activation" NARROW [] synonym: "negative regulation of immune cell activation" EXACT [] synonym: "negative regulation of leucocyte activation" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050866 ! negative regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045321 ! negatively regulates leukocyte activation relationship: RO:0002212 GO:0045321 ! negatively regulates leukocyte activation [Term] id: GO:0002696 name: positive regulation of leukocyte activation def: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "activation of leukocyte activation" NARROW [] synonym: "positive regulation of immune cell activation" EXACT [] synonym: "positive regulation of leucocyte activation" EXACT [] synonym: "stimulation of leukocyte activation" NARROW [] synonym: "up regulation of leukocyte activation" EXACT [] synonym: "up-regulation of leukocyte activation" EXACT [] synonym: "upregulation of leukocyte activation" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050867 ! positive regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045321 ! positively regulates leukocyte activation relationship: RO:0002213 GO:0045321 ! positively regulates leukocyte activation [Term] id: GO:0002697 name: regulation of immune effector process def: "Any process that modulates the frequency, rate, or extent of an immune effector process." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002252 ! regulates immune effector process relationship: RO:0002211 GO:0002252 ! regulates immune effector process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002698 name: negative regulation of immune effector process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "down regulation of immune effector process" EXACT [] synonym: "down-regulation of immune effector process" EXACT [] synonym: "downregulation of immune effector process" EXACT [] synonym: "inhibition of immune effector process" NARROW [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002252 ! negatively regulates immune effector process relationship: RO:0002212 GO:0002252 ! negatively regulates immune effector process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002699 name: positive regulation of immune effector process def: "Any process that activates or increases the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "activation of immune effector process" NARROW [] synonym: "stimulation of immune effector process" NARROW [] synonym: "up regulation of immune effector process" EXACT [] synonym: "up-regulation of immune effector process" EXACT [] synonym: "upregulation of immune effector process" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002252 ! positively regulates immune effector process relationship: RO:0002213 GO:0002252 ! positively regulates immune effector process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002700 name: regulation of production of molecular mediator of immune response def: "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] is_a: GO:0002697 ! regulation of immune effector process is_a: GO:0010468 ! regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002440 ! regulates production of molecular mediator of immune response relationship: RO:0002211 GO:0002440 ! regulates production of molecular mediator of immune response property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002701 name: negative regulation of production of molecular mediator of immune response def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "down regulation of production of molecular mediator of immune response" EXACT [] synonym: "down-regulation of production of molecular mediator of immune response" EXACT [] synonym: "downregulation of production of molecular mediator of immune response" EXACT [] synonym: "inhibition of production of molecular mediator of immune response" NARROW [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010629 ! negative regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002440 ! negatively regulates production of molecular mediator of immune response relationship: RO:0002212 GO:0002440 ! negatively regulates production of molecular mediator of immune response property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002702 name: positive regulation of production of molecular mediator of immune response def: "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "activation of production of molecular mediator of immune response" NARROW [] synonym: "stimulation of production of molecular mediator of immune response" NARROW [] synonym: "up regulation of production of molecular mediator of immune response" EXACT [] synonym: "up-regulation of production of molecular mediator of immune response" EXACT [] synonym: "upregulation of production of molecular mediator of immune response" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010628 ! positive regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002440 ! positively regulates production of molecular mediator of immune response relationship: RO:0002213 GO:0002440 ! positively regulates production of molecular mediator of immune response property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002703 name: regulation of leukocyte mediated immunity def: "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "regulation of immune cell mediated immunity" EXACT [] synonym: "regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002443 ! regulates leukocyte mediated immunity relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0002443 ! regulates leukocyte mediated immunity [Term] id: GO:0002704 name: negative regulation of leukocyte mediated immunity def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "down regulation of leukocyte mediated immunity" EXACT [] synonym: "down-regulation of leukocyte mediated immunity" EXACT [] synonym: "downregulation of leukocyte mediated immunity" EXACT [] synonym: "inhibition of leukocyte mediated immunity" NARROW [] synonym: "negative regulation of immune cell mediated immunity" EXACT [] synonym: "negative regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002443 ! negatively regulates leukocyte mediated immunity relationship: RO:0002212 GO:0002443 ! negatively regulates leukocyte mediated immunity [Term] id: GO:0002705 name: positive regulation of leukocyte mediated immunity def: "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "activation of leukocyte mediated immunity" NARROW [] synonym: "positive regulation of immune cell mediated immunity" EXACT [] synonym: "positive regulation of leucocyte mediated immunity" EXACT [] synonym: "stimulation of leukocyte mediated immunity" NARROW [] synonym: "up regulation of leukocyte mediated immunity" EXACT [] synonym: "up-regulation of leukocyte mediated immunity" EXACT [] synonym: "upregulation of leukocyte mediated immunity" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002443 ! positively regulates leukocyte mediated immunity relationship: RO:0002213 GO:0002443 ! positively regulates leukocyte mediated immunity [Term] id: GO:0002706 name: regulation of lymphocyte mediated immunity def: "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002449 ! regulates lymphocyte mediated immunity relationship: RO:0002211 GO:0002449 ! regulates lymphocyte mediated immunity [Term] id: GO:0002707 name: negative regulation of lymphocyte mediated immunity def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "down regulation of lymphocyte mediated immunity" EXACT [] synonym: "down-regulation of lymphocyte mediated immunity" EXACT [] synonym: "downregulation of lymphocyte mediated immunity" EXACT [] synonym: "inhibition of lymphocyte mediated immunity" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002449 ! negatively regulates lymphocyte mediated immunity relationship: RO:0002212 GO:0002449 ! negatively regulates lymphocyte mediated immunity [Term] id: GO:0002708 name: positive regulation of lymphocyte mediated immunity def: "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "activation of lymphocyte mediated immunity" NARROW [] synonym: "stimulation of lymphocyte mediated immunity" NARROW [] synonym: "up regulation of lymphocyte mediated immunity" EXACT [] synonym: "up-regulation of lymphocyte mediated immunity" EXACT [] synonym: "upregulation of lymphocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002449 ! positively regulates lymphocyte mediated immunity relationship: RO:0002213 GO:0002449 ! positively regulates lymphocyte mediated immunity [Term] id: GO:0002709 name: regulation of T cell mediated immunity def: "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "regulation of T lymphocyte mediated immunity" EXACT [] synonym: "regulation of T-cell mediated immunity" EXACT [] synonym: "regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002706 ! regulation of lymphocyte mediated immunity is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002456 ! regulates T cell mediated immunity relationship: RO:0002211 GO:0002456 ! regulates T cell mediated immunity [Term] id: GO:0002710 name: negative regulation of T cell mediated immunity def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "down regulation of T cell mediated immunity" EXACT [] synonym: "down-regulation of T cell mediated immunity" EXACT [] synonym: "downregulation of T cell mediated immunity" EXACT [] synonym: "inhibition of T cell mediated immunity" NARROW [] synonym: "negative regulation of T lymphocyte mediated immunity" EXACT [] synonym: "negative regulation of T-cell mediated immunity" EXACT [] synonym: "negative regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002456 ! negatively regulates T cell mediated immunity relationship: RO:0002212 GO:0002456 ! negatively regulates T cell mediated immunity [Term] id: GO:0002711 name: positive regulation of T cell mediated immunity def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "activation of T cell mediated immunity" NARROW [] synonym: "positive regulation of T lymphocyte mediated immunity" EXACT [] synonym: "positive regulation of T-cell mediated immunity" EXACT [] synonym: "positive regulation of T-lymphocyte mediated immunity" EXACT [] synonym: "stimulation of T cell mediated immunity" NARROW [] synonym: "up regulation of T cell mediated immunity" EXACT [] synonym: "up-regulation of T cell mediated immunity" EXACT [] synonym: "upregulation of T cell mediated immunity" EXACT [] is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002456 ! positively regulates T cell mediated immunity relationship: RO:0002213 GO:0002456 ! positively regulates T cell mediated immunity [Term] id: GO:0002718 name: regulation of cytokine production involved in immune response alt_id: GO:0002739 alt_id: GO:0002742 def: "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] synonym: "regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "regulation of cytokine secretion involved in immune response" NARROW [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0002700 ! regulation of production of molecular mediator of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002367 ! regulates cytokine production involved in immune response relationship: RO:0002211 GO:0002367 ! regulates cytokine production involved in immune response property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002719 name: negative regulation of cytokine production involved in immune response alt_id: GO:0002740 alt_id: GO:0002743 def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." [GOC:add] synonym: "down regulation of cytokine production during immune response" RELATED [] synonym: "down-regulation of cytokine production during immune response" EXACT [] synonym: "downregulation of cytokine production during immune response" RELATED [] synonym: "inhibition of cytokine production during immune response" RELATED [] synonym: "negative regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "negative regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "negative regulation of cytokine secretion involved in immune response" NARROW [] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002367 ! negatively regulates cytokine production involved in immune response relationship: RO:0002212 GO:0002367 ! negatively regulates cytokine production involved in immune response property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002720 name: positive regulation of cytokine production involved in immune response alt_id: GO:0002741 alt_id: GO:0002744 def: "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] synonym: "activation of cytokine production during immune response" NARROW [] synonym: "positive regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "positive regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "positive regulation of cytokine secretion involved in immune response" NARROW [] synonym: "stimulation of cytokine production during immune response" NARROW [] synonym: "up regulation of cytokine production during immune response" RELATED [] synonym: "up-regulation of cytokine production during immune response" RELATED [] synonym: "upregulation of cytokine production during immune response" RELATED [] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002367 ! positively regulates cytokine production involved in immune response relationship: RO:0002213 GO:0002367 ! positively regulates cytokine production involved in immune response property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0002724 name: regulation of T cell cytokine production def: "Any process that modulates the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "regulation of T lymphocyte cytokine production" EXACT [] synonym: "regulation of T-cell cytokine production" EXACT [] synonym: "regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002369 ! regulates T cell cytokine production relationship: RO:0002211 GO:0002369 ! regulates T cell cytokine production [Term] id: GO:0002725 name: negative regulation of T cell cytokine production def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "down regulation of T cell cytokine production" EXACT [] synonym: "down-regulation of T cell cytokine production" EXACT [] synonym: "downregulation of T cell cytokine production" EXACT [] synonym: "inhibition of T cell cytokine production" NARROW [] synonym: "negative regulation of T lymphocyte cytokine production" EXACT [] synonym: "negative regulation of T-cell cytokine production" EXACT [] synonym: "negative regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002710 ! negative regulation of T cell mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002369 ! negatively regulates T cell cytokine production relationship: RO:0002212 GO:0002369 ! negatively regulates T cell cytokine production [Term] id: GO:0002726 name: positive regulation of T cell cytokine production def: "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "activation of T cell cytokine production" NARROW [] synonym: "positive regulation of T lymphocyte cytokine production" EXACT [] synonym: "positive regulation of T-cell cytokine production" EXACT [] synonym: "positive regulation of T-lymphocyte cytokine production" EXACT [] synonym: "stimulation of T cell cytokine production" NARROW [] synonym: "up regulation of T cell cytokine production" EXACT [] synonym: "up-regulation of T cell cytokine production" EXACT [] synonym: "upregulation of T cell cytokine production" EXACT [] is_a: GO:0002711 ! positive regulation of T cell mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002369 ! positively regulates T cell cytokine production relationship: RO:0002213 GO:0002369 ! positively regulates T cell cytokine production [Term] id: GO:0002730 name: regulation of dendritic cell cytokine production def: "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002371 ! regulates dendritic cell cytokine production relationship: RO:0002211 GO:0002371 ! regulates dendritic cell cytokine production [Term] id: GO:0002731 name: negative regulation of dendritic cell cytokine production def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "down regulation of dendritic cell cytokine production" EXACT [] synonym: "down-regulation of dendritic cell cytokine production" EXACT [] synonym: "downregulation of dendritic cell cytokine production" EXACT [] synonym: "inhibition of dendritic cell cytokine production" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002371 ! negatively regulates dendritic cell cytokine production relationship: RO:0002212 GO:0002371 ! negatively regulates dendritic cell cytokine production [Term] id: GO:0002732 name: positive regulation of dendritic cell cytokine production def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "activation of dendritic cell cytokine production" NARROW [] synonym: "stimulation of dendritic cell cytokine production" NARROW [] synonym: "up regulation of dendritic cell cytokine production" EXACT [] synonym: "up-regulation of dendritic cell cytokine production" EXACT [] synonym: "upregulation of dendritic cell cytokine production" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002371 ! positively regulates dendritic cell cytokine production relationship: RO:0002213 GO:0002371 ! positively regulates dendritic cell cytokine production [Term] id: GO:0002761 name: regulation of myeloid leukocyte differentiation def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] is_a: GO:0045637 ! regulation of myeloid cell differentiation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002573 ! regulates myeloid leukocyte differentiation relationship: RO:0002211 GO:0002573 ! regulates myeloid leukocyte differentiation [Term] id: GO:0002762 name: negative regulation of myeloid leukocyte differentiation def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "down regulation of myeloid leukocyte differentiation" EXACT [] synonym: "down-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "downregulation of myeloid leukocyte differentiation" EXACT [] synonym: "inhibition of myeloid leukocyte differentiation" NARROW [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002573 ! negatively regulates myeloid leukocyte differentiation relationship: RO:0002212 GO:0002573 ! negatively regulates myeloid leukocyte differentiation [Term] id: GO:0002763 name: positive regulation of myeloid leukocyte differentiation def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "activation of myeloid leukocyte differentiation" NARROW [] synonym: "stimulation of myeloid leukocyte differentiation" NARROW [] synonym: "up regulation of myeloid leukocyte differentiation" EXACT [] synonym: "up-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "upregulation of myeloid leukocyte differentiation" EXACT [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002573 ! positively regulates myeloid leukocyte differentiation relationship: RO:0002213 GO:0002573 ! positively regulates myeloid leukocyte differentiation [Term] id: GO:0002790 name: peptide secretion def: "The controlled release of a peptide from a cell or a tissue." [GOC:add] is_a: GO:0015833 ! peptide transport is_a: GO:0046903 ! secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion [Term] id: GO:0002791 name: regulation of peptide secretion def: "Any process that modulates the frequency, rate, or extent of peptide secretion." [GOC:add] is_a: GO:0051046 ! regulation of secretion is_a: GO:0090087 ! regulation of peptide transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002790 ! regulates peptide secretion relationship: RO:0002211 GO:0002790 ! regulates peptide secretion [Term] id: GO:0002792 name: negative regulation of peptide secretion def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "down regulation of peptide secretion" EXACT [] synonym: "down-regulation of peptide secretion" EXACT [] synonym: "downregulation of peptide secretion" EXACT [] synonym: "inhibition of peptide secretion" NARROW [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051048 ! negative regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002790 ! negatively regulates peptide secretion relationship: RO:0002212 GO:0002790 ! negatively regulates peptide secretion [Term] id: GO:0002793 name: positive regulation of peptide secretion def: "Any process that activates or increases the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "activation of peptide secretion" NARROW [] synonym: "stimulation of peptide secretion" NARROW [] synonym: "up regulation of peptide secretion" EXACT [] synonym: "up-regulation of peptide secretion" EXACT [] synonym: "upregulation of peptide secretion" EXACT [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051047 ! positive regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002790 ! positively regulates peptide secretion relationship: RO:0002213 GO:0002790 ! positively regulates peptide secretion [Term] id: GO:0002819 name: regulation of adaptive immune response def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response." [GOC:add] is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002250 ! regulates adaptive immune response relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0002250 ! regulates adaptive immune response [Term] id: GO:0002820 name: negative regulation of adaptive immune response def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "down regulation of adaptive immune response" EXACT [] synonym: "down-regulation of adaptive immune response" EXACT [] synonym: "downregulation of adaptive immune response" EXACT [] synonym: "inhibition of adaptive immune response" NARROW [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050777 ! negative regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002250 ! negatively regulates adaptive immune response relationship: RO:0002212 GO:0002250 ! negatively regulates adaptive immune response [Term] id: GO:0002821 name: positive regulation of adaptive immune response def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "activation of adaptive immune response" NARROW [] synonym: "stimulation of adaptive immune response" NARROW [] synonym: "up regulation of adaptive immune response" EXACT [] synonym: "up-regulation of adaptive immune response" EXACT [] synonym: "upregulation of adaptive immune response" EXACT [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050778 ! positive regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002250 ! positively regulates adaptive immune response relationship: RO:0002213 GO:0002250 ! positively regulates adaptive immune response [Term] id: GO:0002822 name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002819 ! regulation of adaptive immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002460 ! regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0002460 ! regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002823 name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002820 ! negative regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002460 ! negatively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: RO:0002212 GO:0002460 ! negatively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002824 name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002821 ! positive regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002460 ! positively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: RO:0002213 GO:0002460 ! positively regulates adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002831 name: regulation of response to biotic stimulus def: "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009607 ! regulates response to biotic stimulus relationship: RO:0002211 GO:0009607 ! regulates response to biotic stimulus [Term] id: GO:0002832 name: negative regulation of response to biotic stimulus def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "down regulation of response to biotic stimulus" EXACT [] synonym: "down-regulation of response to biotic stimulus" EXACT [] synonym: "downregulation of response to biotic stimulus" EXACT [] synonym: "inhibition of response to biotic stimulus" NARROW [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009607 ! negatively regulates response to biotic stimulus relationship: RO:0002212 GO:0009607 ! negatively regulates response to biotic stimulus [Term] id: GO:0002833 name: positive regulation of response to biotic stimulus def: "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "activation of response to biotic stimulus" NARROW [] synonym: "stimulation of response to biotic stimulus" NARROW [] synonym: "up regulation of response to biotic stimulus" EXACT [] synonym: "up-regulation of response to biotic stimulus" EXACT [] synonym: "upregulation of response to biotic stimulus" EXACT [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009607 ! positively regulates response to biotic stimulus relationship: RO:0002213 GO:0009607 ! positively regulates response to biotic stimulus [Term] id: GO:0002886 name: regulation of myeloid leukocyte mediated immunity def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002444 ! regulates myeloid leukocyte mediated immunity relationship: RO:0002211 GO:0002444 ! regulates myeloid leukocyte mediated immunity [Term] id: GO:0002887 name: negative regulation of myeloid leukocyte mediated immunity def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "down regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "down-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "downregulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "inhibition of myeloid leukocyte mediated immunity" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002444 ! negatively regulates myeloid leukocyte mediated immunity relationship: RO:0002212 GO:0002444 ! negatively regulates myeloid leukocyte mediated immunity [Term] id: GO:0002888 name: positive regulation of myeloid leukocyte mediated immunity def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "activation of myeloid leukocyte mediated immunity" NARROW [] synonym: "stimulation of myeloid leukocyte mediated immunity" NARROW [] synonym: "up regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "up-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "upregulation of myeloid leukocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002444 ! positively regulates myeloid leukocyte mediated immunity relationship: RO:0002213 GO:0002444 ! positively regulates myeloid leukocyte mediated immunity [Term] id: GO:0002932 name: tendon sheath development def: "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." [PMID:20696843] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000304 ! results in development of tendon sheath relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035989 ! tendon development relationship: RO:0002296 UBERON:0000304 ! results in development of tendon sheath created_by: hjd creation_date: 2012-04-23T02:11:22Z [Term] id: GO:0003002 name: regionalization def: "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:isa_complete] synonym: "pattern formation" RELATED [GOC:dph] is_a: GO:0007389 ! pattern specification process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003006 name: developmental process involved in reproduction namespace: biological_process def: "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." [GOC:dph, GOC:isa_complete] synonym: "puberty" NARROW [GOC:dph] synonym: "reproductive developmental process" RELATED [GOC:dph, GOC:tb] is_a: GO:0022414 ! reproductive process is_a: GO:0032502 ! developmental process intersection_of: GO:0022414 ! reproductive process intersection_of: GO:0032502 ! developmental process [Term] id: GO:0003007 name: heart morphogenesis def: "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:dph, GOC:isa_complete] synonym: "cardiac morphogenesis" RELATED [] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007100 ! results in morphogenesis of primary circulatory organ relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007507 ! heart development relationship: RO:0002298 UBERON:0007100 ! results in morphogenesis of primary circulatory organ [Term] id: GO:0003008 name: system process def: "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." [GOC:mtg_cardio] synonym: "organ system process" EXACT [] is_a: GO:0032501 ! multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003009 name: skeletal muscle contraction def: "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." [GOC:mtg_cardio, GOC:mtg_muscle] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue relationship: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0050881 ! musculoskeletal movement [Term] id: GO:0003012 name: muscle system process def: "An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio] subset: goslim_drosophila subset: goslim_generic synonym: "muscle physiological process" RELATED [] is_a: GO:0003008 ! system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003013 name: circulatory system process def: "An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio] subset: goslim_chembl subset: goslim_generic xref: Wikipedia:Circulatory_system is_a: GO:0003008 ! system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003014 name: renal system process def: "An organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10] subset: goslim_generic synonym: "excretory system process" EXACT [] synonym: "kidney system process" RELATED [] is_a: GO:0003008 ! system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003015 name: heart process def: "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:mtg_cardio] synonym: "cardiac process" RELATED [] is_a: GO:0003013 ! circulatory system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003016 name: respiratory system process alt_id: GO:0010802 def: "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." [GOC:dph, GOC:mtg_cardio, GOC:tb] subset: goslim_generic synonym: "respiratory gaseous exchange" EXACT [] is_a: GO:0003008 ! system process relationship: part_of GO:0007585 ! respiratory gaseous exchange by respiratory system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003032 name: detection of oxygen def: "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_cardio] is_a: GO:0009593 ! detection of chemical stimulus is_a: GO:0070482 ! response to oxygen levels [Term] id: GO:0003091 name: renal water homeostasis def: "Renal process involved in the maintenance of an internal steady state of water in the body." [GOC:mtg_cardio] synonym: "water homeostasis by the renal system" EXACT [] xref: Reactome:R-HSA-432040 "Vasopressin regulates renal water homeostasis via Aquaporins" is_a: GO:0003014 ! renal system process is_a: GO:0050891 ! multicellular organismal-level water homeostasis property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003096 name: renal sodium ion transport def: "The directed movement of sodium ions (Na+) by the renal system." [GOC:mtg_cardio] is_a: GO:0003014 ! renal system process is_a: GO:0006814 ! sodium ion transport intersection_of: GO:0006814 ! sodium ion transport intersection_of: BFO:0000066 UBERON:0001008 ! occurs in renal system relationship: BFO:0000066 UBERON:0001008 ! occurs in renal system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003097 name: renal water transport def: "The directed movement of water (H2O) by the renal system." [GOC:mtg_cardio] is_a: GO:0003014 ! renal system process is_a: GO:0006833 ! water transport intersection_of: GO:0006833 ! water transport intersection_of: BFO:0000066 UBERON:0001008 ! occurs in renal system relationship: BFO:0000066 UBERON:0001008 ! occurs in renal system relationship: part_of GO:0003091 ! renal water homeostasis property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0003131 name: mesodermal-endodermal cell signaling def: "Any process that mediates the transfer of information from mesodermal cells to endodermal cells." [GOC:mtg_heart] synonym: "mesodermal-endodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000222 ! has start location mesodermal cell intersection_of: RO:0002232 CL:0000223 ! has end location endodermal cell relationship: RO:0002231 CL:0000222 ! has start location mesodermal cell relationship: RO:0002232 CL:0000223 ! has end location endodermal cell created_by: tb creation_date: 2009-09-22T03:07:34Z [Term] id: GO:0003133 name: endodermal-mesodermal cell signaling def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." [GOC:mtg_heart] synonym: "endodermal-mesodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000223 ! has start location endodermal cell intersection_of: RO:0002232 CL:0000222 ! has end location mesodermal cell relationship: RO:0002231 CL:0000223 ! has start location endodermal cell relationship: RO:0002232 CL:0000222 ! has end location mesodermal cell created_by: tb creation_date: 2009-09-22T03:10:29Z [Term] id: GO:0003142 name: cardiogenic plate morphogenesis def: "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." [GOC:mtg_heart] synonym: "cardiac crescent morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004139 ! results in morphogenesis of cardiogenic plate relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003007 ! heart morphogenesis relationship: RO:0002298 UBERON:0004139 ! results in morphogenesis of cardiogenic plate created_by: tb creation_date: 2009-09-22T04:12:18Z [Term] id: GO:0003143 name: embryonic heart tube morphogenesis def: "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004141 ! results in morphogenesis of heart tube relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0035050 ! embryonic heart tube development relationship: part_of GO:0048562 ! embryonic organ morphogenesis relationship: RO:0002298 UBERON:0004141 ! results in morphogenesis of heart tube created_by: tb creation_date: 2009-09-22T04:21:17Z [Term] id: GO:0003144 name: embryonic heart tube formation def: "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004141 ! results in formation of anatomical entity heart tube relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0003143 ! embryonic heart tube morphogenesis relationship: RO:0002297 UBERON:0004141 ! results in formation of anatomical entity heart tube created_by: tb creation_date: 2009-09-22T04:22:34Z [Term] id: GO:0003145 name: embryonic heart tube formation via epithelial folding def: "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis." [GOC:mtg_heart] is_a: GO:0003144 ! embryonic heart tube formation created_by: tb creation_date: 2009-09-22T04:26:03Z [Term] id: GO:0003147 name: neural crest cell migration involved in heart formation def: "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0060914 ! heart formation relationship: part_of GO:0061308 ! cardiac neural crest cell development involved in heart development created_by: tb creation_date: 2009-09-22T04:29:55Z [Term] id: GO:0003148 name: outflow tract septum morphogenesis def: "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." [GOC:mtg_heart] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004142 ! results in morphogenesis of outflow tract septum relationship: part_of GO:0003151 ! outflow tract morphogenesis relationship: RO:0002298 UBERON:0004142 ! results in morphogenesis of outflow tract septum created_by: tb creation_date: 2009-09-22T07:51:01Z [Term] id: GO:0003149 name: membranous septum morphogenesis def: "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004666 ! results in morphogenesis of interventricular septum membranous part relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060412 ! ventricular septum morphogenesis relationship: RO:0002298 UBERON:0004666 ! results in morphogenesis of interventricular septum membranous part created_by: tb creation_date: 2009-09-22T07:51:41Z [Term] id: GO:0003150 name: muscular septum morphogenesis def: "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." [GOC:mtg_heart] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004667 ! results in morphogenesis of interventricular septum muscular part relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060412 ! ventricular septum morphogenesis relationship: RO:0002298 UBERON:0004667 ! results in morphogenesis of interventricular septum muscular part created_by: tb creation_date: 2009-09-22T07:53:28Z [Term] id: GO:0003151 name: outflow tract morphogenesis def: "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_heart, UBERON:0004145] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004145 ! results in morphogenesis of outflow tract relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003007 ! heart morphogenesis relationship: RO:0002298 UBERON:0004145 ! results in morphogenesis of outflow tract created_by: tb creation_date: 2009-09-22T07:59:24Z [Term] id: GO:0003152 name: morphogenesis of an epithelial fold involved in embryonic heart tube formation def: "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: part_of GO:0003144 ! embryonic heart tube formation relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0003145 ! embryonic heart tube formation via epithelial folding created_by: tb creation_date: 2009-09-23T10:10:24Z [Term] id: GO:0003156 name: regulation of animal organ formation def: "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." [GOC:dph, GOC:mtg_heart, GOC:tb] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048645 ! regulates animal organ formation relationship: RO:0002211 GO:0048645 ! regulates animal organ formation created_by: tb creation_date: 2009-09-30T11:21:09Z [Term] id: GO:0003157 name: endocardium development def: "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002165 ! results in development of endocardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007507 ! heart development relationship: RO:0002296 UBERON:0002165 ! results in development of endocardium created_by: dph creation_date: 2009-10-01T12:42:27Z [Term] id: GO:0003158 name: endothelium development def: "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001986 ! results in development of endothelium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0001986 ! results in development of endothelium created_by: dph creation_date: 2009-10-01T12:50:57Z [Term] id: GO:0003159 name: morphogenesis of an endothelium def: "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001986 ! results in morphogenesis of endothelium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003158 ! endothelium development relationship: RO:0002298 UBERON:0001986 ! results in morphogenesis of endothelium created_by: dph creation_date: 2009-10-01T01:34:06Z [Term] id: GO:0003160 name: endocardium morphogenesis def: "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002165 ! results in morphogenesis of endocardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003157 ! endocardium development relationship: RO:0002298 UBERON:0002165 ! results in morphogenesis of endocardium created_by: dph creation_date: 2009-10-01T01:37:26Z [Term] id: GO:0003161 name: cardiac conduction system development def: "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." [GOC:mtg_heart] synonym: "cardiac impulse conducting system development" EXACT [GOC:mtg_heart] synonym: "heart conduction system development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002350 ! results in development of conducting system of heart relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0002350 ! results in development of conducting system of heart created_by: dph creation_date: 2009-10-01T01:57:16Z [Term] id: GO:0003162 name: atrioventricular node development def: "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." [GOC:mtg_heart] synonym: "AV node development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002352 ! results in development of atrioventricular node relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003161 ! cardiac conduction system development relationship: RO:0002296 UBERON:0002352 ! results in development of atrioventricular node created_by: dph creation_date: 2009-10-01T02:05:13Z [Term] id: GO:0003163 name: sinoatrial node development def: "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." [GOC:mtg_heart] synonym: "SA node development" EXACT [GOC:mtg_heart] synonym: "SAN development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0003228 ! atrial cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002351 ! results in development of sinoatrial node relationship: part_of GO:0003161 ! cardiac conduction system development relationship: RO:0002296 UBERON:0002351 ! results in development of sinoatrial node created_by: dph creation_date: 2009-10-01T02:06:09Z [Term] id: GO:0003164 name: His-Purkinje system development def: "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004146 ! results in development of His-Purkinje system relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0003161 ! cardiac conduction system development relationship: RO:0002296 UBERON:0004146 ! results in development of His-Purkinje system created_by: dph creation_date: 2009-10-01T02:07:12Z [Term] id: GO:0003165 name: Purkinje myocyte development def: "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber development" EXACT [] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002354 ! results in development of cardiac Purkinje fiber relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0003164 ! His-Purkinje system development relationship: RO:0002296 UBERON:0002354 ! results in development of cardiac Purkinje fiber created_by: dph creation_date: 2009-10-01T02:07:50Z [Term] id: GO:0003168 name: Purkinje myocyte differentiation def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber cell differentiation" EXACT [] is_a: GO:0060932 ! His-Purkinje system cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002068 ! results in acquisition of features of Purkinje myocyte relationship: part_of GO:0003165 ! Purkinje myocyte development relationship: RO:0002315 CL:0002068 ! results in acquisition of features of Purkinje myocyte created_by: dph creation_date: 2009-10-01T02:49:54Z [Term] id: GO:0003169 name: coronary vein morphogenesis def: "The process in which the anatomical structures of veins of the heart are generated and organized." [GOC:mtg_heart] is_a: GO:0048845 ! venous blood vessel morphogenesis is_a: GO:0060977 ! coronary vasculature morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004148 ! results in morphogenesis of cardiac vein relationship: RO:0002298 UBERON:0004148 ! results in morphogenesis of cardiac vein created_by: dph creation_date: 2009-10-08T10:45:41Z [Term] id: GO:0003197 name: endocardial cushion development def: "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002062 ! results in development of endocardial cushion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007507 ! heart development relationship: RO:0002296 UBERON:0002062 ! results in development of endocardial cushion created_by: dph creation_date: 2009-10-08T01:17:43Z [Term] id: GO:0003203 name: endocardial cushion morphogenesis def: "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002062 ! results in morphogenesis of endocardial cushion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003197 ! endocardial cushion development relationship: RO:0002298 UBERON:0002062 ! results in morphogenesis of endocardial cushion created_by: dph creation_date: 2009-10-08T01:43:22Z [Term] id: GO:0003204 name: cardiac skeleton development def: "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." [GOC:mtg_heart] synonym: "heart fibrous skeleton development" EXACT [GOC:mtg_heart] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004292 ! results in development of cardiac skeleton relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007507 ! heart development relationship: RO:0002296 UBERON:0004292 ! results in development of cardiac skeleton created_by: dph creation_date: 2009-10-13T09:05:04Z [Term] id: GO:0003205 name: cardiac chamber development def: "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004151 ! results in development of cardiac chamber relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007507 ! heart development relationship: RO:0002296 UBERON:0004151 ! results in development of cardiac chamber created_by: dph creation_date: 2009-10-13T09:11:18Z [Term] id: GO:0003206 name: cardiac chamber morphogenesis def: "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004151 ! results in morphogenesis of cardiac chamber relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003205 ! cardiac chamber development relationship: RO:0002298 UBERON:0004151 ! results in morphogenesis of cardiac chamber created_by: dph creation_date: 2009-10-13T09:14:51Z [Term] id: GO:0003207 name: cardiac chamber formation def: "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004151 ! results in formation of anatomical entity cardiac chamber relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: RO:0002297 UBERON:0004151 ! results in formation of anatomical entity cardiac chamber created_by: dph creation_date: 2009-10-13T09:29:13Z [Term] id: GO:0003208 name: cardiac ventricle morphogenesis def: "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002082 ! results in morphogenesis of cardiac ventricle relationship: part_of GO:0003231 ! cardiac ventricle development relationship: RO:0002298 UBERON:0002082 ! results in morphogenesis of cardiac ventricle created_by: dph creation_date: 2009-10-13T09:38:44Z [Term] id: GO:0003209 name: cardiac atrium morphogenesis def: "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002081 ! results in morphogenesis of cardiac atrium relationship: part_of GO:0003230 ! cardiac atrium development relationship: RO:0002298 UBERON:0002081 ! results in morphogenesis of cardiac atrium created_by: dph creation_date: 2009-10-13T09:39:44Z [Term] id: GO:0003210 name: cardiac atrium formation def: "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002081 ! results in formation of anatomical entity cardiac atrium relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: RO:0002297 UBERON:0002081 ! results in formation of anatomical entity cardiac atrium created_by: dph creation_date: 2009-10-13T09:44:25Z [Term] id: GO:0003211 name: cardiac ventricle formation def: "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002082 ! results in formation of anatomical entity cardiac ventricle relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis relationship: RO:0002297 UBERON:0002082 ! results in formation of anatomical entity cardiac ventricle created_by: dph creation_date: 2009-10-13T09:46:27Z [Term] id: GO:0003212 name: cardiac left atrium morphogenesis def: "The process in which the left cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002079 ! results in morphogenesis of left cardiac atrium relationship: RO:0002298 UBERON:0002079 ! results in morphogenesis of left cardiac atrium created_by: dph creation_date: 2009-10-13T09:48:16Z [Term] id: GO:0003213 name: cardiac right atrium morphogenesis def: "The process in which the right cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002078 ! results in morphogenesis of right cardiac atrium relationship: RO:0002298 UBERON:0002078 ! results in morphogenesis of right cardiac atrium created_by: dph creation_date: 2009-10-13T09:49:03Z [Term] id: GO:0003214 name: cardiac left ventricle morphogenesis def: "The process in which the left cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002084 ! results in morphogenesis of heart left ventricle relationship: RO:0002298 UBERON:0002084 ! results in morphogenesis of heart left ventricle created_by: dph creation_date: 2009-10-13T09:50:08Z [Term] id: GO:0003215 name: cardiac right ventricle morphogenesis def: "The process in which the right cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002080 ! results in morphogenesis of heart right ventricle relationship: RO:0002298 UBERON:0002080 ! results in morphogenesis of heart right ventricle created_by: dph creation_date: 2009-10-13T09:50:57Z [Term] id: GO:0003216 name: cardiac left atrium formation def: "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002079 ! results in formation of anatomical entity left cardiac atrium relationship: part_of GO:0003212 ! cardiac left atrium morphogenesis relationship: RO:0002297 UBERON:0002079 ! results in formation of anatomical entity left cardiac atrium created_by: dph creation_date: 2009-10-13T09:52:31Z [Term] id: GO:0003217 name: cardiac right atrium formation def: "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002078 ! results in formation of anatomical entity right cardiac atrium relationship: part_of GO:0003213 ! cardiac right atrium morphogenesis relationship: RO:0002297 UBERON:0002078 ! results in formation of anatomical entity right cardiac atrium created_by: dph creation_date: 2009-10-13T09:53:12Z [Term] id: GO:0003218 name: cardiac left ventricle formation def: "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002084 ! results in formation of anatomical entity heart left ventricle relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis relationship: RO:0002297 UBERON:0002084 ! results in formation of anatomical entity heart left ventricle created_by: dph creation_date: 2009-10-13T09:54:33Z [Term] id: GO:0003219 name: cardiac right ventricle formation def: "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002080 ! results in formation of anatomical entity heart right ventricle relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis relationship: RO:0002297 UBERON:0002080 ! results in formation of anatomical entity heart right ventricle created_by: dph creation_date: 2009-10-13T09:55:38Z [Term] id: GO:0003220 name: left ventricular cardiac muscle tissue morphogenesis def: "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "left ventricular myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003382 ! results in morphogenesis of cardiac muscle of left ventricle relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis relationship: RO:0002298 UBERON:0003382 ! results in morphogenesis of cardiac muscle of left ventricle created_by: dph creation_date: 2009-10-13T10:18:05Z [Term] id: GO:0003221 name: right ventricular cardiac muscle tissue morphogenesis def: "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "right ventricle myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003381 ! results in morphogenesis of cardiac muscle of right ventricle relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis relationship: RO:0002298 UBERON:0003381 ! results in morphogenesis of cardiac muscle of right ventricle created_by: dph creation_date: 2009-10-13T10:26:33Z [Term] id: GO:0003222 name: ventricular trabecula myocardium morphogenesis def: "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "trabecula carnea morphogenesis" RELATED [GOC:dph] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis is_a: GO:0061384 ! heart trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004126 ! results in morphogenesis of trabecular layer of ventricle relationship: RO:0002298 UBERON:0004126 ! results in morphogenesis of trabecular layer of ventricle created_by: dph creation_date: 2009-10-13T10:33:00Z [Term] id: GO:0003225 name: left ventricular trabecular myocardium morphogenesis def: "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003220 ! left ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005064 ! results in morphogenesis of left ventricular trabecular myocardium relationship: RO:0002298 UBERON:0005064 ! results in morphogenesis of left ventricular trabecular myocardium created_by: dph creation_date: 2009-10-13T10:45:09Z [Term] id: GO:0003227 name: right ventricular trabecular myocardium morphogenesis def: "The process in which the anatomical structures of the right ventricular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003221 ! right ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005066 ! results in morphogenesis of right ventricular trabecular myocardium relationship: RO:0002298 UBERON:0005066 ! results in morphogenesis of right ventricular trabecular myocardium created_by: dph creation_date: 2009-10-13T10:50:59Z [Term] id: GO:0003228 name: atrial cardiac muscle tissue development def: "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "atrial myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004490 ! results in development of cardiac muscle tissue of atrium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0004490 ! results in development of cardiac muscle tissue of atrium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22614" xsd:anyURI created_by: dph creation_date: 2009-10-13T10:53:18Z [Term] id: GO:0003229 name: ventricular cardiac muscle tissue development def: "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "ventricular myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0018649 ! results in development of cardiac muscle tissue of ventricle relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0018649 ! results in development of cardiac muscle tissue of ventricle created_by: dph creation_date: 2009-10-13T10:56:01Z [Term] id: GO:0003230 name: cardiac atrium development def: "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002081 ! results in development of cardiac atrium relationship: RO:0002296 UBERON:0002081 ! results in development of cardiac atrium created_by: dph creation_date: 2009-10-13T11:02:07Z [Term] id: GO:0003231 name: cardiac ventricle development def: "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002082 ! results in development of cardiac ventricle relationship: RO:0002296 UBERON:0002082 ! results in development of cardiac ventricle created_by: dph creation_date: 2009-10-13T11:03:16Z [Term] id: GO:0003235 name: sinus venosus development def: "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002063 ! results in development of sinus venosus relationship: RO:0002296 UBERON:0002063 ! results in development of sinus venosus created_by: dph creation_date: 2009-10-13T11:12:34Z [Term] id: GO:0003236 name: sinus venosus morphogenesis def: "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002063 ! results in morphogenesis of sinus venosus relationship: part_of GO:0003235 ! sinus venosus development relationship: RO:0002298 UBERON:0002063 ! results in morphogenesis of sinus venosus created_by: dph creation_date: 2009-10-13T11:16:52Z [Term] id: GO:0003237 name: sinus venosus formation def: "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002063 ! results in formation of anatomical entity sinus venosus relationship: part_of GO:0003236 ! sinus venosus morphogenesis relationship: RO:0002297 UBERON:0002063 ! results in formation of anatomical entity sinus venosus created_by: dph creation_date: 2009-10-13T11:18:34Z [Term] id: GO:0003241 name: growth involved in heart morphogenesis def: "Developmental growth that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0060560 ! developmental growth involved in morphogenesis intersection_of: GO:0040007 ! growth intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0060419 ! heart growth created_by: dph creation_date: 2009-10-13T11:28:46Z [Term] id: GO:0003245 name: cardiac muscle tissue growth involved in heart morphogenesis def: "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0003241 ! growth involved in heart morphogenesis is_a: GO:0055017 ! cardiac muscle tissue growth intersection_of: GO:0055017 ! cardiac muscle tissue growth intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0055008 ! cardiac muscle tissue morphogenesis created_by: dph creation_date: 2009-10-13T11:44:21Z [Term] id: GO:0003248 name: heart capillary growth def: "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." [GOC:mtg_heart] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0006966 ! results in growth of coronary capillary relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060419 ! heart growth relationship: part_of GO:0060976 ! coronary vasculature development relationship: RO:0002343 UBERON:0006966 ! results in growth of coronary capillary created_by: dph creation_date: 2009-10-13T11:53:12Z [Term] id: GO:0003253 name: cardiac neural crest cell migration involved in outflow tract morphogenesis def: "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061309 ! cardiac neural crest cell development involved in outflow tract morphogenesis created_by: dph creation_date: 2009-10-13T02:14:16Z [Term] id: GO:0003260 name: cardioblast migration def: "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0002664 ! results in movement of cardioblast relationship: RO:0002565 CL:0002664 ! results in movement of cardioblast created_by: dph creation_date: 2009-10-15T01:52:25Z [Term] id: GO:0003272 name: endocardial cushion formation def: "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart, PMID:15797462] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002062 ! results in formation of anatomical entity endocardial cushion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: RO:0002297 UBERON:0002062 ! results in formation of anatomical entity endocardial cushion created_by: dph creation_date: 2009-10-20T08:53:19Z [Term] id: GO:0003273 name: cell migration involved in endocardial cushion formation def: "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0003272 ! endocardial cushion formation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003272 ! endocardial cushion formation created_by: dph creation_date: 2009-10-20T09:08:44Z [Term] id: GO:0003274 name: endocardial cushion fusion def: "The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping." [GOC:mtg_heart] is_a: GO:0061343 ! cell adhesion involved in heart morphogenesis is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003203 ! endocardial cushion morphogenesis created_by: dph creation_date: 2009-10-20T09:26:32Z [Term] id: GO:0003275 name: apoptotic process involved in outflow tract morphogenesis def: "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in outflow tract morphogenesis" NARROW [] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2009-10-20T09:30:01Z [Term] id: GO:0003277 name: apoptotic process involved in endocardial cushion morphogenesis def: "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in endocardial cushion morphogenesis" NARROW [] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003203 ! endocardial cushion morphogenesis created_by: dph creation_date: 2009-10-20T09:37:03Z [Term] id: GO:0003278 name: apoptotic process involved in heart morphogenesis def: "Any apoptotic process that contributes to the shaping of the heart." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in heart morphogenesis" NARROW [] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2009-10-20T09:40:22Z [Term] id: GO:0003279 name: cardiac septum development def: "The progression of a cardiac septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] synonym: "heart septum development" EXACT [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002099 ! results in development of cardiac septum relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003205 ! cardiac chamber development relationship: RO:0002296 UBERON:0002099 ! results in development of cardiac septum created_by: dph creation_date: 2009-10-20T09:45:13Z [Term] id: GO:0003281 name: ventricular septum development def: "The progression of the ventricular septum over time from its formation to the mature structure." [GOC:mtg_heart] synonym: "interventricular septum development" EXACT [GOC:mtg_heart] synonym: "septum inferius development" NARROW [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002094 ! results in development of interventricular septum relationship: part_of GO:0003231 ! cardiac ventricle development relationship: RO:0002296 UBERON:0002094 ! results in development of interventricular septum created_by: dph creation_date: 2009-10-20T10:04:51Z [Term] id: GO:0003283 name: atrial septum development def: "The progression of the atrial septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002085 ! results in development of interatrial septum relationship: part_of GO:0003230 ! cardiac atrium development relationship: RO:0002296 UBERON:0002085 ! results in development of interatrial septum created_by: dph creation_date: 2009-10-20T10:10:38Z [Term] id: GO:0003292 name: cardiac septum cell differentiation def: "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000022 ! results in acquisition of features of cardiac septum cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003279 ! cardiac septum development relationship: RO:0002315 CL:2000022 ! results in acquisition of features of cardiac septum cell created_by: dph creation_date: 2009-10-20T11:03:46Z [Term] id: GO:0003298 name: physiological muscle hypertrophy def: "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." [GOC:mtg_heart] is_a: GO:0014896 ! muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2009-10-22T09:24:51Z [Term] id: GO:0003300 name: cardiac muscle hypertrophy def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." [GOC:mtg_heart] is_a: GO:0014897 ! striated muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2009-10-22T10:33:56Z [Term] id: GO:0003301 name: physiological cardiac muscle hypertrophy def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] is_a: GO:0003298 ! physiological muscle hypertrophy is_a: GO:0003300 ! cardiac muscle hypertrophy relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0055017 ! cardiac muscle tissue growth created_by: dph creation_date: 2009-10-22T10:38:10Z [Term] id: GO:0003309 name: type B pancreatic cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph, PMID:11076772] synonym: "pancreatic B cell differentiation" EXACT [GOC:mah] synonym: "pancreatic beta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000169 ! results in acquisition of features of type B pancreatic cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031018 ! endocrine pancreas development relationship: RO:0002315 CL:0000169 ! results in acquisition of features of type B pancreatic cell created_by: dph creation_date: 2009-10-26T09:27:23Z [Term] id: GO:0003310 name: pancreatic A cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph, PMID:11076772] synonym: "pancreatic alpha cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000171 ! results in acquisition of features of pancreatic A cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031018 ! endocrine pancreas development relationship: RO:0002315 CL:0000171 ! results in acquisition of features of pancreatic A cell created_by: dph creation_date: 2009-10-26T09:28:05Z [Term] id: GO:0003311 name: pancreatic D cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph, PMID:11076772] synonym: "pancreatic delta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000173 ! results in acquisition of features of pancreatic D cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031018 ! endocrine pancreas development relationship: RO:0002315 CL:0000173 ! results in acquisition of features of pancreatic D cell created_by: dph creation_date: 2009-10-26T09:30:27Z [Term] id: GO:0003312 name: pancreatic PP cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph, PMID:11076772] synonym: "pancreatic polypeptide-producing cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002275 ! results in acquisition of features of pancreatic PP cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031018 ! endocrine pancreas development relationship: RO:0002315 CL:0002275 ! results in acquisition of features of pancreatic PP cell created_by: dph creation_date: 2009-10-26T09:32:32Z [Term] id: GO:0003313 name: heart rudiment development def: "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GOC:mtg_heart] synonym: "heart cone development" EXACT [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004291 ! results in development of heart rudiment relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035050 ! embryonic heart tube development relationship: RO:0002296 UBERON:0004291 ! results in development of heart rudiment created_by: dph creation_date: 2009-10-27T08:32:40Z [Term] id: GO:0003314 name: heart rudiment morphogenesis def: "The process in which the anatomical structures of the heart rudiment are generated and organized." [GOC:mtg_heart] synonym: "heart cone morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004291 ! results in morphogenesis of heart rudiment relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003313 ! heart rudiment development relationship: RO:0002298 UBERON:0004291 ! results in morphogenesis of heart rudiment property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22938" xsd:anyURI created_by: dph creation_date: 2009-10-27T08:38:04Z [Term] id: GO:0003315 name: heart rudiment formation def: "The developmental process pertaining to the initial formation of the heart rudiment." [GOC:mtg_heart] synonym: "heart cone formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004291 ! results in formation of anatomical entity heart rudiment relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003314 ! heart rudiment morphogenesis relationship: RO:0002297 UBERON:0004291 ! results in formation of anatomical entity heart rudiment created_by: dph creation_date: 2009-10-27T08:43:37Z [Term] id: GO:0003322 name: pancreatic A cell development def: "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph] synonym: "pancreatic alpha cell development" EXACT [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000171 ! results in development of pancreatic A cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003310 ! pancreatic A cell differentiation relationship: RO:0002296 CL:0000171 ! results in development of pancreatic A cell created_by: dph creation_date: 2009-11-02T08:13:55Z [Term] id: GO:0003323 name: type B pancreatic cell development def: "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph] synonym: "pancreatic B cell development" EXACT [GOC:mah] synonym: "pancreatic beta cell development" EXACT [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000169 ! results in development of type B pancreatic cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003309 ! type B pancreatic cell differentiation relationship: RO:0002296 CL:0000169 ! results in development of type B pancreatic cell created_by: dph creation_date: 2009-11-02T08:20:11Z [Term] id: GO:0003324 name: pancreatic D cell development def: "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph] synonym: "pancreatic delta cell development" EXACT [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000173 ! results in development of pancreatic D cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003311 ! pancreatic D cell differentiation relationship: RO:0002296 CL:0000173 ! results in development of pancreatic D cell created_by: dph creation_date: 2009-11-02T08:23:26Z [Term] id: GO:0003325 name: pancreatic PP cell development def: "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0002275 ! results in development of pancreatic PP cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003312 ! pancreatic PP cell differentiation relationship: RO:0002296 CL:0002275 ! results in development of pancreatic PP cell created_by: dph creation_date: 2009-11-02T08:25:03Z [Term] id: GO:0003330 name: regulation of extracellular matrix constituent secretion def: "Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." [GOC:dph, GOC:tb] is_a: GO:1903053 ! regulation of extracellular matrix organization is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070278 ! regulates extracellular matrix constituent secretion relationship: RO:0002211 GO:0070278 ! regulates extracellular matrix constituent secretion created_by: dph creation_date: 2009-11-02T02:07:40Z [Term] id: GO:0003331 name: positive regulation of extracellular matrix constituent secretion def: "Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." [GOC:dph, GOC:tb] is_a: GO:0003330 ! regulation of extracellular matrix constituent secretion is_a: GO:1903055 ! positive regulation of extracellular matrix organization is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070278 ! positively regulates extracellular matrix constituent secretion relationship: RO:0002213 GO:0070278 ! positively regulates extracellular matrix constituent secretion created_by: dph creation_date: 2009-11-02T02:11:22Z [Term] id: GO:0003332 name: negative regulation of extracellular matrix constituent secretion def: "Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." [GOC:dph, GOC:tb] is_a: GO:0003330 ! regulation of extracellular matrix constituent secretion is_a: GO:1903054 ! negative regulation of extracellular matrix organization is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070278 ! negatively regulates extracellular matrix constituent secretion relationship: RO:0002212 GO:0070278 ! negatively regulates extracellular matrix constituent secretion created_by: dph creation_date: 2009-11-02T02:13:49Z [Term] id: GO:0003333 name: amino acid transmembrane transport def: "The process in which an amino acid is transported across a membrane." [GOC:dph, GOC:tb] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "amino acid membrane transport" EXACT [] is_a: GO:0006865 ! amino acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion created_by: dph creation_date: 2009-11-02T02:36:11Z [Term] id: GO:0003337 name: mesenchymal to epithelial transition involved in metanephros morphogenesis def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] synonym: "metanephric mesenchyme to epithelial transition" RELATED [GOC:dph] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0003338 ! metanephros morphogenesis relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis created_by: dph creation_date: 2009-11-24T09:29:49Z [Term] id: GO:0003338 name: metanephros morphogenesis def: "The process in which the anatomical structures of the metanephros are generated and organized." [GOC:dph, GOC:yaf] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000081 ! results in morphogenesis of metanephros relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002298 UBERON:0000081 ! results in morphogenesis of metanephros created_by: dph creation_date: 2009-11-24T09:32:09Z [Term] id: GO:0003339 name: regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis def: "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003337 ! regulates mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: RO:0002211 GO:0003337 ! regulates mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: dph creation_date: 2009-11-24T09:43:04Z [Term] id: GO:0003340 name: negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis def: "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003337 ! negatively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: RO:0002212 GO:0003337 ! negatively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: dph creation_date: 2009-11-24T09:46:12Z [Term] id: GO:0003341 name: cilium movement alt_id: GO:0036142 def: "The directed, self-propelled movement of a cilium." [GOC:dph, GOC:jl] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "ciliary motility" RELATED [] synonym: "cilium beating" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "flagellar motility" RELATED [] synonym: "flagellar movement" NARROW [GOC:bf] synonym: "flagellum movement" NARROW [] synonym: "microtubule-based flagellum movement" EXACT [] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: RO:0002565 GO:0005929 ! results in movement of cilium intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002565 GO:0005929 ! results in movement of cilium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2009-11-24T09:56:26Z [Term] id: GO:0003342 name: proepicardium development def: "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004160 ! results in development of proepicardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003343 ! septum transversum development relationship: RO:0002296 UBERON:0004160 ! results in development of proepicardium created_by: dph creation_date: 2009-12-01T10:30:17Z [Term] id: GO:0003343 name: septum transversum development def: "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004161 ! results in development of septum transversum relationship: RO:0002296 UBERON:0004161 ! results in development of septum transversum created_by: dph creation_date: 2009-12-01T10:40:17Z [Term] id: GO:0003344 name: pericardium morphogenesis def: "The process in which the anatomical structure of the pericardium is generated and organized." [GOC:dph, PMID:18722343] is_a: GO:0002011 ! morphogenesis of an epithelial sheet is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002407 ! results in morphogenesis of pericardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060039 ! pericardium development relationship: RO:0002298 UBERON:0002407 ! results in morphogenesis of pericardium created_by: dph creation_date: 2009-12-01T10:46:34Z [Term] id: GO:0003348 name: cardiac endothelial cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." [GOC:dph, PMID:18722343] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010008 ! results in acquisition of features of cardiac endothelial cell relationship: RO:0002315 CL:0010008 ! results in acquisition of features of cardiac endothelial cell created_by: dph creation_date: 2009-12-01T11:12:05Z [Term] id: GO:0003352 name: regulation of cilium movement alt_id: GO:1900172 def: "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "regulation of flagellar movement" RELATED [GOC:TermGenie] synonym: "regulation of flagellum movement" RELATED [] synonym: "regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003341 ! regulates cilium movement relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0003341 ! regulates cilium movement property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2009-12-03T10:12:00Z [Term] id: GO:0003353 name: positive regulation of cilium movement alt_id: GO:1900174 def: "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "positive regulation of flagellar movement" RELATED [GOC:TermGenie] synonym: "positive regulation of flagellum movement" RELATED [] synonym: "positive regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003341 ! positively regulates cilium movement relationship: RO:0002213 GO:0003341 ! positively regulates cilium movement property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2009-12-03T10:16:10Z [Term] id: GO:0003354 name: negative regulation of cilium movement alt_id: GO:1900173 def: "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "negative regulation of flagellum movement" RELATED [] synonym: "negative regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003341 ! negatively regulates cilium movement relationship: RO:0002212 GO:0003341 ! negatively regulates cilium movement property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2009-12-03T10:17:47Z [Term] id: GO:0003357 name: noradrenergic neuron differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." [GOC:dph] synonym: "norepinephrine secreting neuron differentiation" EXACT [GOC:dph] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008025 ! results in acquisition of features of noradrenergic neuron relationship: RO:0002315 CL:0008025 ! results in acquisition of features of noradrenergic neuron created_by: dph creation_date: 2009-12-03T10:34:30Z [Term] id: GO:0003358 name: noradrenergic neuron development def: "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] synonym: "norepinephrine secreting neuron development" EXACT [GOC:dph] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0008025 ! results in development of noradrenergic neuron relationship: part_of GO:0003357 ! noradrenergic neuron differentiation relationship: RO:0002296 CL:0008025 ! results in development of noradrenergic neuron created_by: dph creation_date: 2009-12-03T10:38:37Z [Term] id: GO:0003360 name: brainstem development def: "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002298 ! results in development of brainstem relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0002298 ! results in development of brainstem created_by: dph creation_date: 2009-12-03T10:47:20Z [Term] id: GO:0003361 name: noradrenergic neuron differentiation involved in brainstem development def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem." [GOC:dph] is_a: GO:0003357 ! noradrenergic neuron differentiation intersection_of: GO:0003357 ! noradrenergic neuron differentiation intersection_of: part_of GO:0003360 ! brainstem development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003360 ! brainstem development created_by: dph creation_date: 2009-12-03T10:53:30Z [Term] id: GO:0003365 name: establishment of cell polarity involved in ameboidal cell migration def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: part_of GO:0001667 ! ameboidal-type cell migration relationship: part_of GO:0001667 ! ameboidal-type cell migration property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2009-12-08T04:50:41Z [Term] id: GO:0003367 name: cell-cell adhesion involved in ameboidal cell migration def: "The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration relationship: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration relationship: RO:0000053 PATO:0002487 ! bearer of single organismal process quality property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2009-12-08T05:15:49Z [Term] id: GO:0003371 name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: part_of GO:0001667 ! ameboidal-type cell migration relationship: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2009-12-08T05:42:46Z [Term] id: GO:0003379 name: establishment of cell polarity involved in gastrulation cell migration def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: part_of GO:0042074 ! cell migration involved in gastrulation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042074 ! cell migration involved in gastrulation created_by: dph creation_date: 2009-12-09T06:54:44Z [Term] id: GO:0003380 name: establishment or maintenance of cytoskeleton polarity involved in gastrulation def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003371 ! establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: part_of GO:0007369 ! gastrulation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0003379 ! establishment of cell polarity involved in gastrulation cell migration created_by: dph creation_date: 2009-12-09T07:10:57Z [Term] id: GO:0003381 name: epithelial cell morphogenesis involved in gastrulation def: "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0003382 ! epithelial cell morphogenesis intersection_of: part_of GO:0007369 ! gastrulation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007369 ! gastrulation created_by: dph creation_date: 2009-12-09T07:18:53Z [Term] id: GO:0003382 name: epithelial cell morphogenesis def: "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002299 CL:0000066 ! results in maturation of epithelial cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0002064 ! epithelial cell development relationship: RO:0002299 CL:0000066 ! results in maturation of epithelial cell created_by: dph creation_date: 2009-12-09T07:21:06Z [Term] id: GO:0003403 name: optic vesicle formation def: "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004128 ! results in formation of anatomical entity optic vesicle relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003404 ! optic vesicle morphogenesis relationship: part_of GO:0060900 ! embryonic camera-type eye formation relationship: RO:0002297 UBERON:0004128 ! results in formation of anatomical entity optic vesicle created_by: dph creation_date: 2009-12-21T01:42:37Z [Term] id: GO:0003404 name: optic vesicle morphogenesis def: "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004128 ! results in morphogenesis of optic vesicle relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis relationship: RO:0002298 UBERON:0004128 ! results in morphogenesis of optic vesicle created_by: dph creation_date: 2009-12-21T01:54:34Z [Term] id: GO:0003407 name: neural retina development def: "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003902 ! results in development of retinal neural layer relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: RO:0002296 UBERON:0003902 ! results in development of retinal neural layer created_by: dph creation_date: 2009-12-21T02:15:14Z [Term] id: GO:0003411 name: cell motility involved in camera-type eye morphogenesis def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: part_of GO:0048593 ! camera-type eye morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048593 ! camera-type eye morphogenesis created_by: dph creation_date: 2009-12-21T03:04:27Z [Term] id: GO:0003413 name: chondrocyte differentiation involved in endochondral bone morphogenesis def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002062 ! chondrocyte differentiation intersection_of: GO:0002062 ! chondrocyte differentiation intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060351 ! cartilage development involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T08:39:58Z [Term] id: GO:0003414 name: chondrocyte morphogenesis involved in endochondral bone morphogenesis def: "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090171 ! chondrocyte morphogenesis intersection_of: GO:0090171 ! chondrocyte morphogenesis intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003433 ! chondrocyte development involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T08:42:55Z [Term] id: GO:0003416 name: endochondral bone growth def: "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0002513 ! results in growth of endochondral bone relationship: RO:0002343 UBERON:0002513 ! results in growth of endochondral bone created_by: dph creation_date: 2009-12-22T08:52:55Z [Term] id: GO:0003433 name: chondrocyte development involved in endochondral bone morphogenesis def: "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002063 ! chondrocyte development intersection_of: GO:0002063 ! chondrocyte development intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T12:42:44Z [Term] id: GO:0003674 name: gene product or complex activity name: molecular_function alt_id: GO:0005554 def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." [GOC:pdt] def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt] comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "molecular function" EXACT [] is_a: BFO:0000015 ! process is_a: http://rs.tdwg.org/dwc/terms/Event ! Event disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological process property_value: editor_note "This is the same as GO molecular function" xsd:string property_value: IAO:0000111 "molecular_function" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl property_value: IAO:0000589 "molecular process" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0003824 name: catalytic activity def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote_ribbon synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Enzyme is_a: GO:0003674 ! molecular_function property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0005215 name: transporter activity alt_id: GO:0005478 def: "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells." [GOC:ai, GOC:dgf] comment: Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules. subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote subset: goslim_prokaryote_ribbon synonym: "carrier" RELATED [] is_a: GO:0003674 ! molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27621" xsd:anyURI [Term] id: GO:0005275 name: amine transmembrane transporter activity alt_id: GO:0005279 def: "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] synonym: "amine/amide/polyamine channel activity" BROAD [] synonym: "amine/polyamine transmembrane transporter activity" EXACT [] synonym: "amino acid-polyamine transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: part_of GO:0015837 ! amine transport relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0005277 name: acetylcholine transmembrane transporter activity def: "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] xref: Reactome:R-HSA-264615 "Loading of acetylcholine in synaptic vesicles" is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity is_a: GO:1901375 ! acetate ester transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine [Term] id: GO:0005310 name: dicarboxylic acid transmembrane transporter activity alt_id: GO:0005312 alt_id: GO:0015365 def: "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai] synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] synonym: "dicarboxylate carrier" NARROW [] synonym: "dicarboxylic acid permease activity" RELATED [] synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] xref: Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate" xref: Reactome:R-HSA-372843 "SLC25A10 mediates exchange of malate and phosphate" is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:35692 ! has primary input dicarboxylic acid relationship: part_of GO:0006835 ! dicarboxylic acid transport relationship: RO:0004009 CHEBI:35692 ! has primary input dicarboxylic acid [Term] id: GO:0005319 name: lipid transporter activity def: "Enables the directed movement of lipids into, out of or within a cell, or between cells." [GOC:ai] synonym: "apolipoprotein" RELATED [] synonym: "lipophorin" NARROW [] xref: Reactome:R-HSA-1369028 "ABCAs mediate lipid efflux" xref: Reactome:R-HSA-1369052 "ABCAs mediate lipid influx" xref: Reactome:R-HSA-174786 "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex" xref: Reactome:R-HSA-5334794 "FABPs bind LCFAs" xref: Reactome:R-HSA-5682285 "ABCA12 transports lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5682311 "Defective ABCA12 does not transport lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5683672 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5683714 "ABCA3 transports PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5688397 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-6801250 "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane" xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cytosol" xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL" xref: Reactome:R-HSA-8873834 "STARD10 transports PC from ER membrane to lamellar body membrane" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: part_of GO:0006869 {source="GO_REF:0000090"} ! lipid transport relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0005326 name: neurotransmitter transmembrane transporter activity def: "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai, ISBN:0198506732] synonym: "neurotransmitter transporter activity" RELATED [] xref: Reactome:R-HSA-374896 "Uptake of Noradrenaline" xref: Reactome:R-HSA-374919 "Noradrenaline clearance from the synaptic cleft" is_a: GO:0022857 ! transmembrane transporter activity relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0006836 {source="GO_REF:0000090"} ! neurotransmitter transport [Term] id: GO:0005372 name: water transmembrane transporter activity def: "Enables the transfer of water (H2O) from one side of a membrane to the other." [GOC:ai] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:15377 ! has primary input water relationship: part_of GO:0006833 ! water transport relationship: RO:0004009 CHEBI:15377 ! has primary input water [Term] id: GO:0005575 name: cellular_component alt_id: GO:0008372 def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 is_a: BFO:0000040 ! material entity union_of: GO:0032991 ! protein-containing complex union_of: GO:0044423 ! virion component union_of: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0008150 ! biological process property_value: IAO:0000111 "cellular_component" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0005576 name: extracellular region def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical structure [Term] id: GO:0005577 name: fibrinogen complex def: "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." [ISBN:0198547684] synonym: "fibrinogen" EXACT [] synonym: "fibrinogen alpha chain" NARROW [] synonym: "fibrinogen beta chain" NARROW [] synonym: "fibrinogen gamma chain" NARROW [] is_a: GO:0032991 ! protein-containing complex relationship: part_of GO:0005615 ! extracellular space property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0005581 name: collagen trimer def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0005583 name: fibrillar collagen trimer def: "Any triple helical collagen trimer that forms fibrils." [PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0098643 ! fibrillar collagen disjoint_from: GO:0030936 ! transmembrane collagen trimer relationship: part_of GO:0098643 ! fibrillar collagen [Term] id: GO:0005585 name: collagen type II trimer def: "A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils." [PMID:21421911] xref: Wikipedia:Collagen_type_II is_a: GO:0005583 ! fibrillar collagen trimer [Term] id: GO:0005587 name: collagen type IV trimer def: "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." [PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen_type_IV is_a: GO:0098642 ! network-forming collagen trimer relationship: part_of GO:0140154 ! chicken-wire-like collagen network property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30148" xsd:anyURI [Term] id: GO:0005604 name: basement membrane alt_id: GO:0005605 alt_id: GO:0008003 def: "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." [PMID:22505934, PMID:33605520, PMID:39223427] comment: Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer. synonym: "basal lamina" RELATED [] synonym: "basement lamina" RELATED [] synonym: "lamina densa" RELATED [] xref: Wikipedia:Basement_membrane is_a: GO:0031012 ! extracellular matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29267" xsd:anyURI [Term] id: GO:0005614 name: interstitial matrix def: "A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens." [PMID:33605520, PMID:39223427, PMID:8450001] is_a: GO:0031012 ! extracellular matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29267" xsd:anyURI [Term] id: GO:0005615 name: extracellular space def: "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] comment: Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical structure relationship: part_of GO:0005576 ! extracellular region property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0005622 name: intracellular anatomical structure def: "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "internal to cell" EXACT [] synonym: "intracellular" EXACT [] synonym: "nucleocytoplasm" RELATED [GOC:mah] synonym: "protoplasm" EXACT [] synonym: "protoplast" RELATED [GOC:mah] xref: Wikipedia:Intracellular is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17776" xsd:anyURI [Term] id: GO:0005634 name: nucleus def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_yeast synonym: "cell nucleus" EXACT [] synonym: "horsetail nucleus" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757] xref: NIF_Subcellular:sao1702920020 xref: Wikipedia:Cell_nucleus is_a: GO:0043231 ! intracellular membrane-bounded organelle disjoint_from: GO:0005737 ! cytoplasm disjoint_from: GO:0005829 ! cytosol relationship: in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0005635 name: nuclear envelope alt_id: GO:0005636 def: "The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport." [ISBN:0198547684, PMID:16164970] subset: goslim_chembl subset: goslim_generic subset: goslim_plant xref: Wikipedia:Nuclear_envelope is_a: GO:0031967 ! organelle envelope relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005634 ! nucleus relationship: part_of GO:0012505 ! endomembrane system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29832" xsd:anyURI [Term] id: GO:0005640 name: nuclear outer membrane def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." [ISBN:0198547684] synonym: "nucleus outer envelope" EXACT [] synonym: "perinuclear membrane" EXACT [] xref: NIF_Subcellular:sao1617136075 is_a: GO:0031965 ! nuclear membrane is_a: GO:0031968 ! organelle outer membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005634 ! nucleus relationship: bounding_layer_of GO:0005634 ! nucleus relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network [Term] id: GO:0005677 name: chromatin silencing complex def: "Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing." [GOC:mah] is_a: GO:0140513 ! nuclear protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of_part_of GO:0031507 ! heterochromatin formation relationship: capable_of_part_of GO:0031507 ! heterochromatin formation [Term] id: GO:0005694 name: chromosome def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684] comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] xref: Wikipedia:Chromosome is_a: GO:0043232 ! intracellular membraneless organelle [Term] id: GO:0005730 name: nucleolus def: "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast xref: NIF_Subcellular:sao1820400233 xref: Wikipedia:Nucleolus is_a: GO:0043232 ! intracellular membraneless organelle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0031981 ! nuclear lumen [Term] id: GO:0005737 name: cytoplasm def: "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005622 ! intracellular anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23023" xsd:anyURI [Term] id: GO:0005773 name: vacuole def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_yeast synonym: "vacuolar carboxypeptidase Y" RELATED [] xref: Wikipedia:Vacuole is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005774 name: vacuolar membrane def: "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." [GOC:ai] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005773 ! vacuole relationship: bounding_layer_of GO:0005773 ! vacuole relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005773 ! vacuole [Term] id: GO:0005775 name: vacuolar lumen def: "The volume enclosed within the vacuolar membrane." [ISBN:0198506732] is_a: GO:0070013 ! intracellular organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0005773 ! vacuole relationship: part_of GO:0005773 ! vacuole [Term] id: GO:0005794 name: Golgi apparatus def: "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." [ISBN:0198506732, PMID:9695800] comment: Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_yeast synonym: "Golgi" BROAD [] synonym: "Golgi complex" EXACT [] synonym: "Golgi ribbon" NARROW [] xref: NIF_Subcellular:sao451912436 xref: Wikipedia:Golgi_apparatus is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0012505 ! endomembrane system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14798" xsd:anyURI [Term] id: GO:0005798 name: Golgi-associated vesicle def: "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." [GOC:mah] comment: Note that this definition includes vesicles that are transiently associated with the Golgi. synonym: "Golgi vesicle" RELATED [] synonym: "vesicular component" RELATED [NIF_Subcellular:sao138219748] xref: NIF_Subcellular:sao819927218 is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0005829 name: cytosol def: "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." [GOC:hjd, GOC:jl] subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_plant xref: NIF_Subcellular:sao101633890 xref: Wikipedia:Cytosol is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005840 name: ribosome alt_id: GO:0033279 def: "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] xref: NIF_Subcellular:sao1429207766 xref: Wikipedia:Ribosome is_a: GO:0043232 ! intracellular membraneless organelle relationship: capable_of_part_of GO:0006412 ! translation relationship: has_part CHEBI:33697 ! ribonucleic acid relationship: has_part PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17777" xsd:anyURI [Term] id: GO:0005856 name: cytoskeleton def: "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, PMID:16959967, PMID:27419875] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote subset: goslim_yeast xref: Wikipedia:Cytoskeleton is_a: GO:0043232 ! intracellular membraneless organelle [Term] id: GO:0005874 name: microtubule def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] subset: goslim_metagenomics synonym: "microtubuli" EXACT [] synonym: "microtubulus" EXACT [] synonym: "neurotubule" NARROW [NIF_Subcellular:sao248349196] xref: NIF_Subcellular:sao1846835077 xref: Wikipedia:Microtubule is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0015630 ! microtubule cytoskeleton [Term] id: GO:0005879 name: axonemal microtubule def: "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." [GOC:cilia, ISBN:0815316194] is_a: GO:0005881 ! cytoplasmic microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005930 ! axoneme relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005930 ! axoneme property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0005880 name: nuclear microtubule def: "Any microtubule in the nucleus of a cell." [GOC:mah] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005634 ! nucleus relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005634 ! nucleus [Term] id: GO:0005881 name: cytoplasmic microtubule def: "Any microtubule in the cytoplasm of a cell." [GOC:mah] synonym: "non-spindle-associated astral microtubule" NARROW [] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005882 name: intermediate filament def: "A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins." [ISBN:0198506732, PMID:17493611, PMID:17551517, PMID:7979242] synonym: "intermediate filament associated protein" RELATED [] synonym: "type I intermediate filament associated protein" RELATED [] synonym: "type II intermediate filament associated protein" RELATED [] xref: FMA:63851 xref: NIF_Subcellular:sao952483289 xref: Wikipedia:Intermediate_filament is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0045111 ! intermediate filament cytoskeleton [Term] id: GO:0005884 name: actin filament def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339] synonym: "microfilament" EXACT [] xref: FMA:63850 xref: NIF_Subcellular:sao1588493326 xref: Wikipedia:Actin is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0005886 name: plasma membrane alt_id: GO:0005887 alt_id: GO:0005904 def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] synonym: "cytoplasmic membrane" EXACT [] synonym: "inner endospore membrane" NARROW [] synonym: "integral component of plasma membrane" NARROW [] synonym: "integral to plasma membrane" NARROW [] synonym: "juxtamembrane" BROAD [] synonym: "plasma membrane lipid bilayer" NARROW [GOC:mah] synonym: "plasmalemma" EXACT [] xref: NIF_Subcellular:sao1663586795 xref: Wikipedia:Cell_membrane is_a: GO:0016020 ! membrane relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0005902 name: microvillus def: "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." [ISBN:0815316194] comment: Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta. subset: goslim_pir synonym: "microvilli" RELATED [NIF_Subcellular:sao671419673] xref: NIF_Subcellular:sao671419673 xref: Wikipedia:Microvillus is_a: GO:0098858 ! actin-based cell projection relationship: has_part GO:0032432 ! actin filament bundle relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of CL:0000066 ! epithelial cell [Term] id: GO:0005911 name: cell-cell junction def: "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264] synonym: "cell-cell contact region" BROAD [] synonym: "cell-cell contact zone" BROAD [] synonym: "intercellular junction" EXACT [NIF_Subcellular:sao1395777368] xref: NIF_Subcellular:sao1922892319 is_a: GO:0070161 ! anchoring junction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22122" xsd:anyURI property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0005929 name: cilium alt_id: GO:0072372 def: "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." [GOC:cilia, GOC:curators, GOC:kmv, GOC:vw, ISBN:0198547684, PMID:16824949, PMID:17009929, PMID:20144998] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir synonym: "eukaryotic flagellum" EXACT [] synonym: "flagellum" RELATED [] synonym: "microtubule-based flagellum" EXACT [] synonym: "primary cilium" NARROW [] xref: FMA:67181 xref: NIF_Subcellular:sao787716553 xref: Wikipedia:Cilium is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0120025 ! plasma membrane bounded cell projection relationship: has_part GO:0030990 ! intraciliary transport particle relationship: in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0005930 name: axoneme alt_id: GO:0035085 alt_id: GO:0035086 def: "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, ISBN:0198547684] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane. subset: goslim_pir synonym: "ciliary axoneme" EXACT [] synonym: "cilium axoneme" EXACT [] synonym: "flagellar axoneme" EXACT [] synonym: "flagellum axoneme" EXACT [] xref: Wikipedia:Axoneme is_a: GO:0110165 ! cellular anatomical structure relationship: has_part GO:0005874 ! microtubule relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005856 ! cytoskeleton relationship: part_of GO:0097014 ! ciliary plasm property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0005938 name: cell cortex def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_yeast synonym: "cell periphery" RELATED [] synonym: "ectoplasm" NARROW [] synonym: "peripheral cytoplasm" RELATED [] xref: Wikipedia:Cell_cortex is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0071944 ! cell periphery relationship: part_of GO:0071944 ! cell periphery property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26298" xsd:anyURI [Term] id: GO:0005975 name: carbohydrate metabolic process alt_id: GO:0044261 alt_id: GO:0044723 def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:mah, ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "carbohydrate metabolism" EXACT [] xref: Reactome:R-HSA-71387 "Metabolism of carbohydrates" xref: Wikipedia:Carbohydrate_metabolism is_a: GO:0044238 ! primary metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:16646 ! has primary input or output carbohydrate relationship: RO:0004007 CHEBI:16646 ! has primary input or output carbohydrate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22880" xsd:anyURI created_by: jl creation_date: 2012-10-23T15:40:34Z [Term] id: GO:0005976 name: polysaccharide metabolic process alt_id: GO:0044263 def: "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [ISBN:0198547684] subset: goslim_pir synonym: "glycan metabolic process" NARROW [] synonym: "glycan metabolism" NARROW [] synonym: "multicellular organismal polysaccharide metabolic process" NARROW [] synonym: "polysaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18154 ! has primary input or output polysaccharide relationship: RO:0004007 CHEBI:18154 ! has primary input or output polysaccharide [Term] id: GO:0005977 name: glycogen metabolic process def: "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." [ISBN:0198506732] synonym: "glycogen metabolism" EXACT [] xref: Reactome:R-HSA-8982491 "Glycogen metabolism" is_a: GO:0006112 ! energy reserve metabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:28087 ! has primary input or output glycogen relationship: RO:0004007 CHEBI:28087 ! has primary input or output glycogen [Term] id: GO:0005978 name: glycogen biosynthetic process def: "The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen anabolism" EXACT [] synonym: "glycogen biosynthesis" EXACT [] synonym: "glycogen formation" EXACT [] synonym: "glycogen synthesis" EXACT [] xref: MetaCyc:PWY-7900 {source="skos:narrowMatch"} xref: Reactome:R-HSA-3322077 "Glycogen synthesis" is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009250 ! glucan biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:28087 ! has primary output glycogen relationship: RO:0004008 CHEBI:28087 ! has primary output glycogen property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28968" xsd:anyURI [Term] id: GO:0005979 name: regulation of glycogen biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "regulation of glycogen anabolism" EXACT [] synonym: "regulation of glycogen biosynthesis" EXACT [] synonym: "regulation of glycogen formation" EXACT [] synonym: "regulation of glycogen synthesis" EXACT [] is_a: GO:0010962 ! regulation of glucan biosynthetic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005978 ! regulates glycogen biosynthetic process relationship: RO:0002211 GO:0005978 ! regulates glycogen biosynthetic process [Term] id: GO:0005980 name: glycogen catabolic process def: "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen breakdown" EXACT [] synonym: "glycogen catabolism" EXACT [] synonym: "glycogen degradation" EXACT [] synonym: "glycogenolysis" EXACT [GOC:sl] xref: MetaCyc:PWY-7662 {source="skos:narrowMatch"} xref: Reactome:R-HSA-70221 "Glycogen breakdown (glycogenolysis)" is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009251 ! glucan catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:28087 ! has primary input glycogen relationship: RO:0004009 CHEBI:28087 ! has primary input glycogen property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28527" xsd:anyURI [Term] id: GO:0005981 name: regulation of glycogen catabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "regulation of glycogen breakdown" EXACT [] synonym: "regulation of glycogen catabolism" EXACT [] synonym: "regulation of glycogen degradation" EXACT [] synonym: "regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0043470 ! regulation of carbohydrate catabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005980 ! regulates glycogen catabolic process relationship: RO:0002211 GO:0005980 ! regulates glycogen catabolic process [Term] id: GO:0005996 name: monosaccharide metabolic process def: "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [ISBN:0198506732] synonym: "monosaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0044281 ! small molecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35381 ! has primary input or output monosaccharide relationship: RO:0004007 CHEBI:35381 ! has primary input or output monosaccharide [Term] id: GO:0006006 name: glucose metabolic process def: "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." [ISBN:0198506732] synonym: "cellular glucose metabolic process" EXACT [GOC:vw] synonym: "glucose metabolism" EXACT [] xref: Reactome:R-HSA-70326 "Glucose metabolism" is_a: GO:0019318 ! hexose metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:4167 ! has primary input or output D-glucopyranose relationship: RO:0004007 CHEBI:4167 ! has primary input or output D-glucopyranose [Term] id: GO:0006007 name: glucose catabolic process def: "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose." [GOC:ai] synonym: "glucose breakdown" EXACT [] synonym: "glucose catabolism" EXACT [] synonym: "glucose degradation" EXACT [] is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019320 ! hexose catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose relationship: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose [Term] id: GO:0006022 name: aminoglycan metabolic process def: "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan metabolism" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:22506 ! has primary input or output aminoglycan relationship: RO:0004007 CHEBI:22506 ! has primary input or output aminoglycan [Term] id: GO:0006023 name: aminoglycan biosynthetic process def: "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan anabolism" EXACT [] synonym: "aminoglycan biosynthesis" EXACT [] synonym: "aminoglycan formation" EXACT [] synonym: "aminoglycan synthesis" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:22506 ! has primary output aminoglycan relationship: RO:0004008 CHEBI:22506 ! has primary output aminoglycan [Term] id: GO:0006024 name: glycosaminoglycan biosynthetic process def: "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units." [PMID:38500384] synonym: "glycosaminoglycan anabolism" EXACT [] synonym: "glycosaminoglycan biosynthesis" EXACT [] synonym: "glycosaminoglycan formation" EXACT [] synonym: "glycosaminoglycan synthesis" EXACT [] is_a: GO:0006023 ! aminoglycan biosynthetic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18085 ! has primary output glycosaminoglycan relationship: RO:0004008 CHEBI:18085 ! has primary output glycosaminoglycan property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29745" xsd:anyURI [Term] id: GO:0006026 name: aminoglycan catabolic process def: "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan breakdown" EXACT [] synonym: "aminoglycan catabolism" EXACT [] synonym: "aminoglycan degradation" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:22506 ! has primary input aminoglycan relationship: RO:0004009 CHEBI:22506 ! has primary input aminoglycan [Term] id: GO:0006027 name: glycosaminoglycan catabolic process def: "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units." [PMID:38500384] synonym: "glycosaminoglycan breakdown" EXACT [] synonym: "glycosaminoglycan catabolism" EXACT [] synonym: "glycosaminoglycan degradation" EXACT [] xref: Reactome:R-HSA-2024101 "CS/DS degradation" is_a: GO:0006026 ! aminoglycan catabolic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18085 ! has primary input glycosaminoglycan relationship: RO:0004009 CHEBI:18085 ! has primary input glycosaminoglycan property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29745" xsd:anyURI [Term] id: GO:0006082 name: organic acid metabolic process def: "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] subset: goslim_pir synonym: "organic acid metabolism" EXACT [] is_a: GO:0044281 ! small molecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:64709 ! has primary input or output organic acid relationship: RO:0004007 CHEBI:64709 ! has primary input or output organic acid [Term] id: GO:0006083 name: acetate metabolic process def: "The chemical reactions and pathways involving acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate metabolism" EXACT [] is_a: GO:0032787 ! monocarboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:30089 ! has primary input or output acetate relationship: RO:0004007 CHEBI:30089 ! has primary input or output acetate [Term] id: GO:0006091 name: generation of precursor metabolites and energy def: "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." [GOC:jl] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_pombe subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "energy pathways" BROAD [] synonym: "intermediary metabolism" RELATED [GOC:mah] synonym: "metabolic energy generation" RELATED [] is_a: GO:0008152 ! metabolic process [Term] id: GO:0006094 name: gluconeogenesis def: "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [MetaCyc:GLUCONEO-PWY] synonym: "glucose biosynthesis" EXACT [] synonym: "glucose biosynthetic process" EXACT [] xref: MetaCyc:GLUCONEO-PWY {source="skos:narrowMatch"} xref: MetaCyc:PWY-6142 {source="skos:narrowMatch"} xref: MetaCyc:PWY66-399 {source="skos:narrowMatch"} xref: Reactome:R-HSA-70263 "Gluconeogenesis" xref: Wikipedia:Gluconeogenesis is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019319 ! hexose biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:4167 ! has primary output D-glucopyranose relationship: RO:0004008 CHEBI:4167 ! has primary output D-glucopyranose property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28953" xsd:anyURI [Term] id: GO:0006109 name: regulation of carbohydrate metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." [GOC:go_curators] synonym: "regulation of carbohydrate metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005975 ! regulates carbohydrate metabolic process relationship: RO:0002211 GO:0005975 ! regulates carbohydrate metabolic process [Term] id: GO:0006111 name: regulation of gluconeogenesis alt_id: GO:0090526 def: "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [GOC:go_curators] synonym: "regulation of gluconeogenesis involved in cellular glucose homeostasis" RELATED [] synonym: "regulation of glucose biosynthesis" BROAD [] synonym: "regulation of glucose biosynthetic process" BROAD [] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006094 ! regulates gluconeogenesis relationship: RO:0002211 GO:0006094 ! regulates gluconeogenesis created_by: tb creation_date: 2013-01-18T12:47:43Z [Term] id: GO:0006112 name: energy reserve metabolic process def: "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen." [GOC:mah] subset: goslim_pir synonym: "energy reserve metabolism" EXACT [] is_a: GO:0015980 ! energy derivation by oxidation of organic compounds [Term] id: GO:0006139 name: nucleobase-containing compound metabolic process alt_id: GO:0055134 def: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] subset: goslim_pir subset: goslim_plant synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0044238 ! primary metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:61120 ! has primary input or output nucleobase-containing molecular entity relationship: RO:0004007 CHEBI:61120 ! has primary input or output nucleobase-containing molecular entity [Term] id: GO:0006325 name: chromatin organization alt_id: GO:0006333 alt_id: GO:0006336 alt_id: GO:0016568 alt_id: GO:0031497 alt_id: GO:0034724 def: "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." [PMID:20404130] subset: goslim_generic subset: goslim_pombe subset: goslim_yeast synonym: "chromatin assembly" NARROW [] synonym: "chromatin assembly or disassembly" RELATED [] synonym: "chromatin assembly/disassembly" RELATED [] synonym: "chromatin maintenance" BROAD [] synonym: "chromatin modification" RELATED [] synonym: "chromatin organisation" EXACT [GOC:mah] synonym: "DNA replication-independent chromatin assembly" NARROW [] synonym: "DNA replication-independent chromatin organization" NARROW [] synonym: "DNA replication-independent nucleosome organisation" NARROW [] synonym: "DNA replication-independent nuclesome assembly" NARROW [] synonym: "establishment of chromatin architecture" EXACT [GOC:mah] synonym: "establishment or maintenance of chromatin architecture" EXACT [GOC:mah] synonym: "transcription-coupled nucleosome assembly" NARROW [] xref: Reactome:R-HSA-4839726 "Chromatin organization" is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0000785 ! results in organization of chromatin relationship: RO:0002592 GO:0000785 ! results in organization of chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22130" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23549" xsd:anyURI [Term] id: GO:0006338 name: chromatin remodeling alt_id: GO:0043044 def: "A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication." [GOC:jid, GOC:vw, PMID:12042764, PMID:12697820] synonym: "ATP-dependent chromatin remodeling" NARROW [] synonym: "ATP-dependent chromatin remodelling" NARROW [] synonym: "chromatin modeling" EXACT [] synonym: "chromatin modelling" EXACT [] synonym: "chromatin remodelling" EXACT [] is_a: GO:0006325 ! chromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21732" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21748" xsd:anyURI [Term] id: GO:0006399 name: tRNA metabolic process def: "The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established." [ISBN:0198506732] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe synonym: "tRNA metabolism" EXACT [] is_a: GO:0016070 ! RNA metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 SO:0000253 ! has primary input or output relationship: RO:0004007 SO:0000253 ! has primary input or output [Term] id: GO:0006401 name: RNA catabolic process def: "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] subset: goslim_yeast synonym: "RNA breakdown" EXACT [] synonym: "RNA catabolism" EXACT [] synonym: "RNA degradation" EXACT [] is_a: GO:0016070 ! RNA metabolic process is_a: GO:0141188 ! nucleic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0006403 name: RNA localization def: "A process in which RNA is transported to, or maintained in, a specific location." [GOC:ai] subset: goslim_drosophila synonym: "establishment and maintenance of RNA localization" EXACT [] synonym: "RNA localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization [Term] id: GO:0006404 name: RNA import into nucleus def: "The import of RNA from the cytoplasm to the nucleus." [GOC:ma] synonym: "RNA import into cell nucleus" EXACT [] synonym: "RNA transport from cytoplasm to nucleus" EXACT [] synonym: "RNA-nucleus import" EXACT [] is_a: GO:0050658 ! RNA transport is_a: GO:0051170 ! import into nucleus intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0031981 ! has target end location nuclear lumen intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0006405 name: RNA export from nucleus def: "The directed movement of RNA from the nucleus to the cytoplasm." [GOC:ma] synonym: "RNA export from cell nucleus" EXACT [] synonym: "RNA export out of nucleus" EXACT [] synonym: "RNA transport from nucleus to cytoplasm" EXACT [] synonym: "RNA-nucleus export" EXACT [] is_a: GO:0050658 ! RNA transport is_a: GO:0051168 ! nuclear export intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0031981 ! has target start location nuclear lumen intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0006409 name: tRNA export from nucleus def: "The directed movement of tRNA from the nucleus to the cytoplasm." [GOC:ma] synonym: "tRNA export from cell nucleus" EXACT [] synonym: "tRNA export out of nucleus" EXACT [] synonym: "tRNA transport from nucleus to cytoplasm" EXACT [] synonym: "tRNA-nucleus export" EXACT [] is_a: GO:0006405 ! RNA export from nucleus is_a: GO:0051031 ! tRNA transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0031981 ! has target start location nuclear lumen intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope intersection_of: RO:0004009 CHEBI:17843 ! has primary input transfer RNA [Term] id: GO:0006412 name: translation alt_id: GO:0006416 alt_id: GO:0006453 alt_id: GO:0043037 def: "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." [GOC:go_curators] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_prokaryote_ribbon synonym: "protein translation" EXACT [] xref: Reactome:R-HSA-72766 "Translation" xref: Wikipedia:Translation_(genetics) is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0019538 ! protein metabolic process is_a: GO:0043604 ! amide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_part GO:0000048 ! peptidyltransferase activity intersection_of: part_of GO:0010467 ! gene expression intersection_of: RO:0004008 PR:000000001 ! has primary output protein relationship: ends_with GO:0006415 ! translational termination relationship: has_part GO:0000048 ! peptidyltransferase activity relationship: has_part GO:0006414 ! translational elongation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0160307 ! protein biosynthetic process relationship: RO:0004008 PR:000000001 ! has primary output protein relationship: starts_with GO:0006413 ! translational initiation [Term] id: GO:0006413 name: translational initiation alt_id: GO:0006440 alt_id: GO:0006454 def: "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [ISBN:019879276X] subset: goslim_yeast synonym: "biopolymerisation" BROAD [] synonym: "biopolymerization" BROAD [] synonym: "protein synthesis initiation" BROAD [] synonym: "translation initiation" EXACT [] xref: Reactome:R-HSA-72613 "Eukaryotic Translation Initiation" is_a: GO:0008152 ! metabolic process relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0006412 ! translation relationship: starts_with GO:0001677 ! formation of translation initiation ternary complex [Term] id: GO:0006414 name: translational elongation alt_id: GO:0006442 alt_id: GO:0006455 def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." [GOC:ems] subset: goslim_yeast synonym: "protein synthesis elongation" BROAD [] synonym: "translation elongation" EXACT [] xref: Reactome:R-HSA-156842 "Eukaryotic Translation Elongation" is_a: GO:0009059 ! macromolecule biosynthetic process relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0006412 ! translation [Term] id: GO:0006415 name: translational termination alt_id: GO:0006443 alt_id: GO:0006456 def: "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." [GOC:hjd, ISBN:019879276X] synonym: "protein synthesis termination" BROAD [] synonym: "translation termination" EXACT [] synonym: "translational complex disassembly" EXACT [] xref: Reactome:R-HSA-72764 "Eukaryotic Translation Termination" is_a: GO:0032984 ! protein-containing complex disassembly relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0006412 ! translation [Term] id: GO:0006417 name: regulation of translation alt_id: GO:0006445 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] subset: goslim_yeast synonym: "regulation of protein anabolism" EXACT [] synonym: "regulation of protein biosynthesis" EXACT [] synonym: "regulation of protein formation" EXACT [] synonym: "regulation of protein synthesis" EXACT [] is_a: GO:0010608 ! post-transcriptional regulation of gene expression is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006412 ! regulates translation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0006412 ! regulates translation [Term] id: GO:0006446 name: regulation of translational initiation def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006413 ! regulates translational initiation relationship: RO:0002211 GO:0006413 ! regulates translational initiation [Term] id: GO:0006448 name: regulation of translational elongation def: "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006414 ! regulates translational elongation relationship: RO:0002211 GO:0006414 ! regulates translational elongation [Term] id: GO:0006449 name: regulation of translational termination def: "Any process that modulates the frequency, rate or extent of translational termination." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006415 ! regulates translational termination relationship: RO:0002211 GO:0006415 ! regulates translational termination [Term] id: GO:0006516 name: glycoprotein catabolic process def: "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein breakdown" EXACT [] synonym: "glycoprotein catabolism" EXACT [] synonym: "glycoprotein degradation" EXACT [] is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:0030163 ! protein catabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein [Term] id: GO:0006518 name: peptide metabolic process def: "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:go_curators] subset: goslim_pir synonym: "peptide metabolism" EXACT [] xref: Reactome:R-HSA-2980736 "Peptide hormone metabolism" is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:60466 ! has primary input or output peptide zwitterion relationship: RO:0004007 CHEBI:60466 ! has primary input or output peptide zwitterion [Term] id: GO:0006520 name: amino acid metabolic process alt_id: GO:0006519 def: "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." [ISBN:0198506732] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "amino acid and derivative metabolism" RELATED [] synonym: "cellular amino acid and derivative metabolic process" RELATED [] synonym: "cellular amino acid metabolic process" EXACT [] synonym: "cellular amino acid metabolism" EXACT [] is_a: GO:0044238 ! primary metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35238 ! has primary input or output amino-acid zwitterion relationship: RO:0004007 CHEBI:35238 ! has primary input or output amino-acid zwitterion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0006521 name: regulation of amino acid metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." [GOC:go_curators] synonym: "regulation of amino acid metabolism" EXACT [] xref: Reactome:R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006520 ! regulates amino acid metabolic process relationship: RO:0002211 GO:0006520 ! regulates amino acid metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] id: GO:0006576 name: biogenic amine metabolic process def: "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine metabolism" EXACT [] synonym: "cellular biogenic amine metabolic process" EXACT [] is_a: GO:0009308 ! amine metabolic process [Term] id: GO:0006581 name: acetylcholine catabolic process def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine breakdown" EXACT [] synonym: "acetylcholine catabolism" EXACT [] synonym: "acetylcholine degradation" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine [Term] id: GO:0006584 name: catecholamine metabolic process def: "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine metabolism" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009712 ! catechol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33567 ! has primary input or output catecholamine relationship: RO:0004007 CHEBI:33567 ! has primary input or output catecholamine [Term] id: GO:0006606 name: protein import into nucleus def: "The directed movement of a protein from the cytoplasm to the nucleus." [GOC:jl] synonym: "establishment of protein localization to nucleus" EXACT [GOC:mah] synonym: "protein import into cell nucleus" EXACT [] synonym: "protein nucleus import" EXACT [] synonym: "protein transport from cytoplasm to nucleus" EXACT [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0034504 ! protein localization to nucleus is_a: GO:0051170 ! import into nucleus is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0031981 ! has target end location nuclear lumen intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0006611 name: protein export from nucleus alt_id: GO:0097349 def: "The directed movement of a protein from the nucleus into the cytoplasm." [GOC:jl] synonym: "copper-induced protein export from nucleus" RELATED [GOC:al] synonym: "protein export from cell nucleus" EXACT [] synonym: "protein export out of nucleus" EXACT [] synonym: "protein transport from nucleus to cytoplasm" EXACT [] synonym: "protein-nucleus export" EXACT [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0051168 ! nuclear export intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0031981 ! has target start location nuclear lumen intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0006629 name: lipid metabolic process def: "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." [GOC:ma] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_pombe subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "lipid metabolism" EXACT [] xref: Reactome:R-HSA-556833 "Metabolism of lipids" xref: Wikipedia:Lipid_metabolism is_a: GO:0044238 ! primary metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18059 ! has primary input or output lipid relationship: RO:0004007 CHEBI:18059 ! has primary input or output lipid [Term] id: GO:0006643 name: membrane lipid metabolic process def: "The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] synonym: "membrane lipid metabolism" EXACT [] is_a: GO:0006629 ! lipid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: BFO:0000066 GO:0016020 ! occurs in membrane intersection_of: RO:0004007 CHEBI:18059 ! has primary input or output lipid relationship: BFO:0000066 GO:0016020 ! occurs in membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] id: GO:0006694 name: steroid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." [GOC:go_curators] synonym: "steroid anabolism" EXACT [] synonym: "steroid biosynthesis" EXACT [] synonym: "steroid formation" EXACT [] synonym: "steroid synthesis" EXACT [] synonym: "steroidogenesis" EXACT [] xref: Wikipedia:Steroid_metabolisms#Steroid_biosynthesis is_a: GO:0008202 ! steroid metabolic process is_a: GO:0008610 ! lipid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35341 ! has primary output steroid relationship: RO:0004008 CHEBI:35341 ! has primary output steroid [Term] id: GO:0006699 name: bile acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid anabolism" EXACT [] synonym: "bile acid biosynthesis" EXACT [] synonym: "bile acid formation" EXACT [] synonym: "bile acid synthesis" EXACT [] xref: Reactome:R-HSA-192105 "Synthesis of bile acids and bile salts" is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:36235 ! has primary output bile acid anion relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0004008 CHEBI:36235 ! has primary output bile acid anion [Term] id: GO:0006706 name: steroid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:go_curators] synonym: "steroid breakdown" EXACT [] synonym: "steroid catabolism" EXACT [] synonym: "steroid degradation" EXACT [] is_a: GO:0008202 ! steroid metabolic process is_a: GO:0016042 ! lipid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35341 ! has primary input steroid relationship: RO:0004009 CHEBI:35341 ! has primary input steroid [Term] id: GO:0006790 name: sulfur compound metabolic process def: "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:ai] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "sulfur metabolism" EXACT [] synonym: "sulphur metabolic process" EXACT [] synonym: "sulphur metabolism" EXACT [] xref: Wikipedia:Sulfur_metabolism is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:26835 ! has primary input or output sulfur molecular entity relationship: RO:0004007 CHEBI:26835 ! has primary input or output sulfur molecular entity [Term] id: GO:0006810 name: transport namespace: biological_process alt_id: GO:0015457 alt_id: GO:0015460 alt_id: GO:0044765 def: "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." [GOC:dos, GOC:dph, GOC:jl, GOC:mah] comment: Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote subset: goslim_prokaryote_ribbon synonym: "single-organism transport" RELATED [] xref: Reactome:R-HSA-382551 "Transport of small molecules" is_a: GO:0051234 ! establishment of localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI created_by: jl creation_date: 2012-12-13T16:25:32Z [Term] id: GO:0006811 name: monoatomic ion transport def: "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:ai] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "ion transport" BROAD [] xref: Reactome:R-HSA-425393 "Transport of inorganic cations/anions and amino acids/oligopeptides" is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion relationship: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion [Term] id: GO:0006812 name: monoatomic cation transport alt_id: GO:0006819 alt_id: GO:0015674 alt_id: GO:0072512 def: "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:ai] synonym: "cation transport" BROAD [] synonym: "di-, tri-valent inorganic cation transport" NARROW [GOC:mah] synonym: "trivalent inorganic cation transport" NARROW [] is_a: GO:0006811 ! monoatomic ion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation relationship: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation [Term] id: GO:0006814 name: sodium ion transport alt_id: GO:0006834 alt_id: GO:0016974 def: "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] synonym: "sodium channel auxiliary protein activity" RELATED [GOC:mah] synonym: "sodium transport" EXACT [] synonym: "sodium/potassium transport" BROAD [] synonym: "sodium:calcium exchange" NARROW [] synonym: "sodium:solute transport" NARROW [] is_a: GO:0030001 ! metal ion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) relationship: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) [Term] id: GO:0006833 name: water transport def: "The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] xref: Reactome:R-HSA-445717 "Aquaporin-mediated transport" is_a: GO:0042044 ! fluid transport intersection_of: GO:0042044 ! fluid transport intersection_of: RO:0004009 CHEBI:15377 ! has primary input water relationship: RO:0004009 CHEBI:15377 ! has primary input water [Term] id: GO:0006835 name: dicarboxylic acid transport alt_id: GO:0006841 def: "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "sodium:dicarboxylate transport" RELATED [] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion relationship: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion [Term] id: GO:0006836 name: neurotransmitter transport def: "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai] subset: goslim_pir synonym: "sodium:neurotransmitter transport" NARROW [] xref: Reactome:R-HSA-181429 "Serotonin Neurotransmitter Release Cycle" xref: Reactome:R-HSA-181430 "Norepinephrine Neurotransmitter Release Cycle" xref: Reactome:R-HSA-210500 "Glutamate Neurotransmitter Release Cycle" xref: Reactome:R-HSA-212676 "Dopamine Neurotransmitter Release Cycle" xref: Reactome:R-HSA-264642 "Acetylcholine Neurotransmitter Release Cycle" is_a: GO:0006810 ! transport relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0006837 name: serotonin transport def: "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] is_a: GO:0015844 ! monoamine transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) relationship: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0006846 name: acetate transport def: "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015718 ! monocarboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0006847 name: plasma membrane acetate transport def: "The directed movement of acetate across a plasma membrane." [GOC:ai] is_a: GO:0035433 ! acetate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0002342 GO:0005886 ! results in transport across plasma membrane [Term] id: GO:0006858 name: extracellular transport def: "The transport of substances that occurs outside cells." [GOC:go_curators] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region relationship: BFO:0000066 GO:0005576 ! occurs in extracellular region [Term] id: GO:0006860 name: extracellular amino acid transport def: "The directed extracellular movement of amino acids." [GOC:ai] is_a: GO:0006858 ! extracellular transport is_a: GO:0006865 ! amino acid transport intersection_of: GO:0006865 ! amino acid transport intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region [Term] id: GO:0006865 name: amino acid transport alt_id: GO:0006866 def: "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir subset: goslim_yeast xref: Reactome:R-HSA-352230 "Amino acid transport across the plasma membrane" is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion relationship: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion [Term] id: GO:0006869 name: lipid transport def: "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [ISBN:0198506732] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast xref: Reactome:R-HSA-1369062 "ABC transporters in lipid homeostasis" is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: part_of GO:0010876 ! lipid localization relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0006873 name: intracellular monoatomic ion homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:mah] subset: goslim_yeast synonym: "cellular ion homeostasis" BROAD [] synonym: "cellular monoatomic ion homeostasis" EXACT [] is_a: GO:0050801 ! monoatomic ion homeostasis is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: RO:0002332 CHEBI:24867 ! regulates levels of monoatomic ion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] id: GO:0006883 name: intracellular sodium ion homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell." [GOC:ai, GOC:mah] synonym: "cellular sodium ion homeostasis" EXACT [] is_a: GO:0030003 ! intracellular monoatomic cation homeostasis is_a: GO:0055078 ! sodium ion homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis intersection_of: RO:0002332 CHEBI:29101 ! regulates levels of sodium(1+) [Term] id: GO:0006884 name: cell volume homeostasis def: "Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of cell volume" EXACT [GOC:dph, GOC:tb] is_a: GO:0008361 ! regulation of cell size is_a: GO:0019725 ! cellular homeostasis [Term] id: GO:0006886 name: intracellular protein transport alt_id: GO:0032779 def: "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." [GOC:mah] subset: goslim_generic subset: goslim_prokaryote synonym: "copper-induced intracellular protein transport" RELATED [GOC:al] is_a: GO:0015031 ! protein transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: part_of GO:0008104 ! intracellular protein localization [Term] id: GO:0006887 name: exocytosis alt_id: GO:0016194 alt_id: GO:0016195 def: "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." [GOC:mah, ISBN:0716731363, PMID:22323285] subset: goslim_yeast synonym: "nonselective vesicle exocytosis" RELATED [] synonym: "vesicle exocytosis" EXACT [] xref: Wikipedia:Exocytosis is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0032940 ! secretion by cell intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: RO:0002608 GO:0070382 ! process has causal agent exocytic vesicle relationship: has_part GO:0099500 ! vesicle fusion to plasma membrane relationship: RO:0002608 GO:0070382 ! process has causal agent exocytic vesicle [Term] id: GO:0006892 name: post-Golgi vesicle-mediated transport def: "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." [GOC:ai, GOC:mah] synonym: "post-Golgi transport" EXACT [] xref: Reactome:R-HSA-199992 "trans-Golgi Network Vesicle Budding" is_a: GO:0048193 ! Golgi vesicle transport [Term] id: GO:0006893 name: Golgi to plasma membrane transport def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." [ISBN:0716731363] synonym: "Golgi to plasma membrane vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus [Term] id: GO:0006896 name: Golgi to vacuole transport def: "The directed movement of substances from the Golgi to the vacuole." [GOC:ai] synonym: "Golgi to vacuole vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0007034 ! vacuolar transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0005773 ! has target end location vacuole relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus relationship: RO:0002339 GO:0005773 ! has target end location vacuole [Term] id: GO:0006897 name: endocytosis alt_id: GO:0016193 alt_id: GO:0016196 alt_id: GO:0098701 def: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis] subset: goslim_yeast synonym: "endocytic import into cell" EXACT [] synonym: "nonselective vesicle endocytosis" RELATED [] synonym: "plasma membrane invagination" NARROW [] synonym: "vesicle endocytosis" EXACT [] xref: Wikipedia:Endocytosis is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0098657 ! import into cell relationship: has_part GO:0006900 ! vesicle budding from membrane relationship: has_part GO:0010324 ! membrane invagination relationship: RO:0002339 GO:0031410 ! has target end location cytoplasmic vesicle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25268" xsd:anyURI [Term] id: GO:0006900 name: vesicle budding from membrane alt_id: GO:0006902 alt_id: GO:1902591 def: "The evagination of a membrane, resulting in formation of a vesicle." [GOC:jid, GOC:tb] synonym: "membrane evagination" EXACT [] synonym: "nonselective vesicle assembly" RELATED [] synonym: "single organism membrane budding" RELATED [GOC:TermGenie] synonym: "single-organism membrane budding" RELATED [] synonym: "vesicle biosynthesis" EXACT [] synonym: "vesicle budding" RELATED [] synonym: "vesicle formation" EXACT [] is_a: GO:0016050 ! vesicle organization is_a: GO:0061024 ! membrane organization relationship: part_of GO:0016192 ! vesicle-mediated transport created_by: jl creation_date: 2013-12-19T15:26:17Z [Term] id: GO:0006903 name: vesicle targeting def: "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo." [GOC:mah, PMID:17335816] is_a: GO:0009987 ! cellular process relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0016192 ! vesicle-mediated transport relationship: part_of GO:0051650 ! establishment of vesicle localization [Term] id: GO:0006906 name: vesicle fusion def: "Fusion of the membrane of a transport vesicle with its target membrane." [GOC:jid] is_a: GO:0016050 ! vesicle organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0012506 ! results in fusion of vesicle membrane relationship: part_of GO:0016192 ! vesicle-mediated transport relationship: RO:0012008 GO:0012506 ! results in fusion of vesicle membrane [Term] id: GO:0006909 name: phagocytosis def: "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [ISBN:0198506732] xref: Reactome:R-HSA-9664417 "Leishmania phagocytosis" xref: Wikipedia:Phagocytosis is_a: GO:0006897 ! endocytosis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0006913 name: nucleocytoplasmic transport alt_id: GO:0000063 def: "The directed movement of molecules between the nucleus and the cytoplasm." [GOC:go_curators] comment: Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe synonym: "nucleocytoplasmic shuttling" NARROW [] is_a: GO:0051169 ! nuclear transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope intersection_of: RO:0002344 GO:0005829 ! results in transport to from or in cytosol intersection_of: RO:0002344 GO:0031981 ! results in transport to from or in nuclear lumen relationship: RO:0002342 GO:0005635 ! results in transport across nuclear envelope relationship: RO:0002344 GO:0005829 ! results in transport to from or in cytosol relationship: RO:0002344 GO:0031981 ! results in transport to from or in nuclear lumen [Term] id: GO:0006915 name: apoptotic process alt_id: GO:0006917 alt_id: GO:0008632 def: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] synonym: "activation of apoptosis" NARROW [] synonym: "apoptosis" NARROW [] synonym: "apoptosis activator activity" RELATED [] synonym: "apoptosis signaling" NARROW [] synonym: "apoptotic cell death" EXACT [GOC:sl] synonym: "apoptotic program" NARROW [GOC:add] synonym: "apoptotic programmed cell death" EXACT [] synonym: "caspase-dependent programmed cell death" RELATED [] synonym: "cell suicide" BROAD [] synonym: "cellular suicide" BROAD [] synonym: "commitment to apoptosis" RELATED [] synonym: "induction of apoptosis" RELATED [] synonym: "induction of apoptosis by p53" RELATED [] synonym: "programmed cell death by apoptosis" EXACT [] synonym: "signaling (initiator) caspase activity" RELATED [] synonym: "type I programmed cell death" NARROW [] xref: Reactome:R-HSA-109581 "Apoptosis" xref: Wikipedia:Apoptosis is_a: GO:0012501 ! programmed cell death relationship: ends_with GO:0097194 ! execution phase of apoptosis relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: starts_with GO:0097190 ! apoptotic signaling pathway property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0006921 name: cellular component disassembly involved in execution phase of apoptosis def: "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb] synonym: "cellular component disassembly involved in apoptosis" NARROW [] synonym: "cellular component disassembly involved in apoptotic process" BROAD [] synonym: "disassembly of cell structures" BROAD [] is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: part_of GO:0097194 ! execution phase of apoptosis relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: part_of GO:0097194 ! execution phase of apoptosis property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0006936 name: muscle contraction def: "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." [GOC:ef, GOC:mtg_muscle, ISBN:0198506732] subset: goslim_pir xref: Reactome:R-HSA-445355 "Smooth Muscle Contraction" xref: Wikipedia:Muscle_contraction is_a: GO:0003012 ! muscle system process relationship: BFO:0000066 UBERON:0002385 ! occurs in muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0006937 name: regulation of muscle contraction def: "Any process that modulates the frequency, rate or extent of muscle contraction." [GOC:go_curators] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006936 ! regulates muscle contraction relationship: RO:0002211 GO:0006936 ! regulates muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0006939 name: smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "visceral muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue relationship: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0006940 name: regulation of smooth muscle contraction def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006939 ! regulates smooth muscle contraction relationship: RO:0002211 GO:0006939 ! regulates smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0006941 name: striated muscle contraction def: "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." [GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "sarcomeric muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction relationship: BFO:0000066 UBERON:0002036 ! occurs in striated muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0006942 name: regulation of striated muscle contraction def: "Any process that modulates the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006941 ! regulates striated muscle contraction relationship: RO:0002211 GO:0006941 ! regulates striated muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0006949 name: syncytium formation def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." [ISBN:0198506732] subset: goslim_pir is_a: GO:0009987 ! cellular process is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 CL:0000228 ! results in formation of anatomical entity multinucleate cell relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002297 CL:0000228 ! results in formation of anatomical entity multinucleate cell [Term] id: GO:0006950 name: response to stress def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant subset: goslim_plant_ribbon synonym: "response to abiotic stress" RELATED [] synonym: "response to biotic stress" RELATED [] is_a: GO:0050896 ! response to stimulus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26810" xsd:anyURI [Term] id: GO:0006952 name: defense response alt_id: GO:0002217 alt_id: GO:0042829 def: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators] synonym: "antimicrobial peptide activity" RELATED [] synonym: "defence response" EXACT [] synonym: "defense/immunity protein activity" RELATED [] synonym: "physiological defense response" EXACT [] is_a: GO:0006950 ! response to stress [Term] id: GO:0006954 name: inflammatory response def: "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." [GO_REF:0000022, ISBN:0198506732] subset: goslim_generic synonym: "inflammation" BROAD [] xref: Wikipedia:Inflammation is_a: GO:0006952 ! defense response relationship: in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0006955 name: immune response def: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add] subset: goslim_drosophila is_a: GO:0002376 ! immune system process is_a: GO:0050896 ! response to stimulus property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0006996 name: organelle organization alt_id: GO:1902589 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_pir synonym: "organelle organisation" EXACT [] synonym: "organelle organization and biogenesis" RELATED [GOC:dph, GOC:jl, GOC:mah] synonym: "single organism organelle organization" EXACT [GOC:TermGenie] synonym: "single-organism organelle organization" RELATED [] xref: Reactome:R-HSA-1852241 "Organelle biogenesis and maintenance" is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0043226 ! results in organization of organelle relationship: RO:0002592 GO:0043226 ! results in organization of organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI created_by: jl creation_date: 2013-12-19T15:25:51Z [Term] id: GO:0006997 name: nucleus organization alt_id: GO:0048287 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] subset: goslim_candida subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "nuclear morphology" RELATED [] synonym: "nuclear organisation" EXACT [] synonym: "nuclear organization" EXACT [] synonym: "nuclear organization and biogenesis" RELATED [GOC:mah] synonym: "nucleus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005634 ! results in organization of nucleus relationship: RO:0002592 GO:0005634 ! results in organization of nucleus [Term] id: GO:0006998 name: nuclear envelope organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] synonym: "nuclear envelope organisation" EXACT [GOC:mah] synonym: "nuclear envelope organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005635 ! results in organization of nuclear envelope relationship: part_of GO:0006997 ! nucleus organization relationship: part_of GO:0010256 ! endomembrane system organization relationship: RO:0002592 GO:0005635 ! results in organization of nuclear envelope [Term] id: GO:0007000 name: nucleolus organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [GOC:dph, GOC:jid, GOC:jl, GOC:mah] synonym: "nucleolus organisation" EXACT [] synonym: "nucleolus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006997 ! nucleus organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005730 ! results in organization of nucleolus relationship: RO:0002592 GO:0005730 ! results in organization of nucleolus [Term] id: GO:0007009 name: plasma membrane organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl synonym: "plasma membrane organisation" EXACT [] synonym: "plasma membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005886 ! results in organization of plasma membrane relationship: part_of GO:0010256 ! endomembrane system organization relationship: RO:0002592 GO:0005886 ! results in organization of plasma membrane [Term] id: GO:0007010 name: cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_prokaryote subset: goslim_yeast synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] synonym: "cytoskeletal regulator activity" RELATED [] synonym: "cytoskeleton organisation" EXACT [] synonym: "cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005856 ! results in organization of cytoskeleton relationship: RO:0002592 GO:0005856 ! results in organization of cytoskeleton [Term] id: GO:0007015 name: actin filament organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:mah] synonym: "actin filament organisation" EXACT [] synonym: "regulation of actin filament localization" NARROW [] is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005884 ! results in organization of actin filament relationship: part_of GO:0030036 ! actin cytoskeleton organization relationship: RO:0002592 GO:0005884 ! results in organization of actin filament [Term] id: GO:0007017 name: microtubule-based process def: "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah] subset: goslim_chembl is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule relationship: RO:0002608 GO:0005874 ! process has causal agent microtubule property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0007018 name: microtubule-based movement def: "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] subset: goslim_drosophila subset: goslim_generic xref: Reactome:R-HSA-983189 "Kinesins" is_a: GO:0007017 ! microtubule-based process [Term] id: GO:0007019 name: microtubule depolymerization def: "The removal of tubulin heterodimers from one or both ends of a microtubule." [ISBN:0815316194] synonym: "microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "microtubule depolymerization during nuclear congression" NARROW [] synonym: "microtubule disassembly" EXACT [] synonym: "microtubule shortening" EXACT [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051261 ! protein depolymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005874 ! results in disassembly of microtubule relationship: RO:0002590 GO:0005874 ! results in disassembly of microtubule [Term] id: GO:0007020 name: microtubule nucleation def: "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." [GOC:go_curators, ISBN:0815316194, PMID:12517712] xref: Wikipedia:Microtubule_nucleation is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0046785 ! microtubule polymerization [Term] id: GO:0007026 name: negative regulation of microtubule depolymerization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." [GOC:mah, ISBN:0815316194] synonym: "down regulation of microtubule depolymerization" EXACT [] synonym: "down-regulation of microtubule depolymerization" EXACT [] synonym: "downregulation of microtubule depolymerization" EXACT [] synonym: "inhibition of microtubule depolymerization" NARROW [] synonym: "microtubule rescue" NARROW [GOC:dph, GOC:tb] synonym: "microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of microtubule disassembly" EXACT [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901880 ! negative regulation of protein depolymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007019 ! negatively regulates microtubule depolymerization relationship: RO:0002212 GO:0007019 ! negatively regulates microtubule depolymerization [Term] id: GO:0007027 name: negative regulation of axonemal microtubule depolymerization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." [GOC:dph, GOC:mah] synonym: "axonemal microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule depolymerization in axoneme" RELATED [GOC:dph] is_a: GO:0007026 ! negative regulation of microtubule depolymerization is_a: GO:0010937 ! regulation of cytoplasmic microtubule depolymerization is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060404 ! negatively regulates axonemal microtubule depolymerization relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002212 GO:0060404 ! negatively regulates axonemal microtubule depolymerization [Term] id: GO:0007028 name: cytoplasm organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:curators, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "cytoplasm organisation" EXACT [] synonym: "cytoplasm organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005737 ! results in organization of cytoplasm relationship: RO:0002592 GO:0005737 ! results in organization of cytoplasm [Term] id: GO:0007030 name: Golgi organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "Golgi apparatus organization" EXACT [] synonym: "Golgi organisation" EXACT [] synonym: "Golgi organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005794 ! results in organization of Golgi apparatus relationship: part_of GO:0010256 ! endomembrane system organization relationship: RO:0002592 GO:0005794 ! results in organization of Golgi apparatus [Term] id: GO:0007033 name: vacuole organization alt_id: GO:0044086 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GOC:mah] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "vacuolar assembly" NARROW [GOC:mah] synonym: "vacuole biogenesis" RELATED [GOC:mah] synonym: "vacuole organisation" EXACT [] synonym: "vacuole organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005773 ! results in organization of vacuole relationship: RO:0002592 GO:0005773 ! results in organization of vacuole [Term] id: GO:0007034 name: vacuolar transport def: "The directed movement of substances into, out of or within a vacuole." [GOC:ai] subset: goslim_chembl is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002344 GO:0005773 ! results in transport to from or in vacuole relationship: RO:0002344 GO:0005773 ! results in transport to from or in vacuole [Term] id: GO:0007039 name: protein catabolic process in the vacuole def: "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." [GOC:mah, GOC:vw] synonym: "vacuolar protein breakdown" RELATED [] synonym: "vacuolar protein catabolic process" RELATED [] synonym: "vacuolar protein catabolism" RELATED [] synonym: "vacuolar protein degradation" RELATED [] is_a: GO:0030163 ! protein catabolic process intersection_of: GO:0030163 ! protein catabolic process intersection_of: BFO:0000066 GO:0005773 ! occurs in vacuole relationship: BFO:0000066 GO:0005773 ! occurs in vacuole [Term] id: GO:0007043 name: cell-cell junction assembly def: "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." [GOC:ai] synonym: "intercellular junction assembly" EXACT [] is_a: GO:0034329 ! cell junction assembly is_a: GO:0045216 ! cell-cell junction organization intersection_of: GO:0034329 ! cell junction assembly intersection_of: RO:0002588 GO:0005911 ! results in assembly of cell-cell junction relationship: RO:0002588 GO:0005911 ! results in assembly of cell-cell junction property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007049 name: cell cycle def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators, GOC:mtg_cell_cycle] subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon synonym: "cell-division cycle" EXACT [] xref: Reactome:R-HSA-1640170 "Cell Cycle" xref: Wikipedia:Cell_cycle is_a: GO:0009987 ! cellular process [Term] id: GO:0007059 name: chromosome segregation def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:jl, GOC:mah, GOC:mtg_cell_cycle, GOC:vw] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_prokaryote subset: goslim_yeast synonym: "chromosome division" EXACT [] synonym: "chromosome transmission" RELATED [] xref: Wikipedia:Chromosome_segregation is_a: GO:0022402 ! cell cycle process [Term] id: GO:0007076 name: mitotic chromosome condensation def: "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194] xref: Reactome:R-HSA-2299718 "Condensation of Prophase Chromosomes" xref: Reactome:R-HSA-2514853 "Condensation of Prometaphase Chromosomes" is_a: GO:0030261 ! chromosome condensation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0030261 ! chromosome condensation intersection_of: part_of GO:0000278 ! mitotic cell cycle relationship: part_of GO:0000070 ! mitotic sister chromatid segregation [Term] id: GO:0007077 name: mitotic nuclear membrane disassembly def: "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." [GOC:bf, PMID:32848252] synonym: "local NEB" BROAD [] synonym: "mitotic nuclear envelope breakdown" EXACT [] synonym: "mitotic nuclear envelope catabolism" RELATED [] synonym: "mitotic nuclear envelope degradation" RELATED [] synonym: "mitotic nuclear envelope disassembly" RELATED [] synonym: "NEB" BROAD [] synonym: "nuclear envelope breakdown" BROAD [] xref: Reactome:R-HSA-2980766 "Nuclear Envelope Breakdown" is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0000278 ! mitotic cell cycle [Term] id: GO:0007088 name: regulation of mitotic nuclear division def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "regulation of mitosis" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0140014 ! regulates mitotic nuclear division relationship: RO:0002211 GO:0140014 ! regulates mitotic nuclear division [Term] id: GO:0007097 name: nuclear migration alt_id: GO:0040023 def: "The directed movement of the nucleus to a specific location within a cell." [GOC:ai] synonym: "establishment of cell nucleus localization" RELATED [] synonym: "establishment of localization of nucleus" RELATED [] synonym: "establishment of nucleus localisation" RELATED [GOC:mah] synonym: "establishment of nucleus localization" RELATED [] synonym: "establishment of position of nucleus" EXACT [] synonym: "nuclear movement" EXACT [] synonym: "nuclear positioning" EXACT [] synonym: "nucleus migration" EXACT [] synonym: "nucleus positioning" EXACT [] synonym: "positioning of nucleus" EXACT [] is_a: GO:0046907 ! intracellular transport is_a: GO:0051647 ! nucleus localization is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0004009 GO:0005634 ! has primary input nucleus [Term] id: GO:0007113 name: endomitotic cell cycle def: "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." [GOC:curators, GOC:dos, GOC:expert_vm] comment: Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins. synonym: "endomitosis" RELATED [] xref: Wikipedia:Mitosis#Endomitosis is_a: GO:0000278 ! mitotic cell cycle [Term] id: GO:0007135 name: meiosis II def: "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." [GOC:dph, GOC:mah, ISBN:0198547684] synonym: "meiosis II nuclear division" EXACT [] xref: Wikipedia:Meiosis#Meiosis_II is_a: GO:0061983 ! meiosis II cell cycle process is_a: GO:0140013 ! meiotic nuclear division [Term] id: GO:0007140 name: male meiotic nuclear division def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." [GOC:dph, GOC:mah, GOC:vw] synonym: "male meiosis" RELATED [] synonym: "male nuclear division" BROAD [] is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0048232 ! male gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle relationship: part_of GO:0048232 ! male gamete generation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007142 name: male meiosis II def: "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline." [GOC:dph, GOC:mah] synonym: "male meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007140 ! male meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: part_of GO:0048232 ! male gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007143 name: female meiotic nuclear division def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." [GOC:dph, GOC:ems, GOC:mah, GOC:vw] comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'. synonym: "female meiosis" BROAD [] synonym: "female meiotic division" BROAD [] is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0007292 ! female gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle relationship: part_of GO:0007292 ! female gamete generation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007147 name: female meiosis II def: "The cell cycle process in which the second meiotic division occurs in the female germline." [GOC:mah] synonym: "female meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007143 ! female meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: part_of GO:0007292 ! female gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007154 name: cell communication def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] subset: goslim_pir subset: goslim_plant xref: Wikipedia:Cell_signaling is_a: GO:0009987 ! cellular process [Term] id: GO:0007155 name: cell adhesion alt_id: GO:0098602 def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "cell adhesion molecule activity" RELATED [] synonym: "single organism cell adhesion" RELATED [] xref: Wikipedia:Cell_adhesion is_a: GO:0009987 ! cellular process created_by: dos creation_date: 2014-04-15T15:59:10Z [Term] id: GO:0007159 name: leukocyte cell-cell adhesion def: "The attachment of a leukocyte to another cell via adhesion molecules." [GOC:go_curators] synonym: "leukocyte adhesion" EXACT [] synonym: "leukocyte cell adhesion" EXACT [] is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: RO:0000057 CL:0000738 ! has participant leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0000057 CL:0000738 ! has participant leukocyte [Term] id: GO:0007162 name: negative regulation of cell adhesion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "cell adhesion receptor inhibitor activity" RELATED [] synonym: "down regulation of cell adhesion" EXACT [] synonym: "down-regulation of cell adhesion" EXACT [] synonym: "downregulation of cell adhesion" EXACT [] synonym: "inhibition of cell adhesion" NARROW [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007155 ! negatively regulates cell adhesion relationship: RO:0002212 GO:0007155 ! negatively regulates cell adhesion [Term] id: GO:0007163 name: establishment or maintenance of cell polarity alt_id: GO:0030012 alt_id: GO:0030467 def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote synonym: "cell polarity" RELATED [GOC:mah, GOC:vw] synonym: "establishment and/or maintenance of cell polarity" RELATED [] synonym: "establishment and/or maintenance of cell polarization" RELATED [] is_a: GO:0009987 ! cellular process [Term] id: GO:0007165 name: signal transduction alt_id: GO:0023014 alt_id: GO:0023015 alt_id: GO:0023016 alt_id: GO:0023033 alt_id: GO:0023045 def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant subset: goslim_plant_ribbon synonym: "signaling cascade" NARROW [] synonym: "signaling pathway" RELATED [] synonym: "signalling cascade" NARROW [] synonym: "signalling pathway" RELATED [] xref: Reactome:R-HSA-212718 "EGFR interacts with phospholipase C-gamma" xref: Wikipedia:Signal_transduction is_a: GO:0009987 ! cellular process is_a: GO:0050794 ! regulation of cellular process relationship: part_of GO:0007154 ! cell communication relationship: part_of GO:0023052 ! signaling relationship: part_of GO:0051716 ! cellular response to stimulus [Term] id: GO:0007267 name: cell-cell signaling def: "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." [GOC:dos, GOC:mah] subset: goslim_chembl subset: goslim_plant synonym: "cell-cell signalling" EXACT [] is_a: GO:0007154 ! cell communication is_a: GO:0023052 ! signaling [Term] id: GO:0007268 name: chemical synaptic transmission def: "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:jl, MeSH:D009435] subset: goslim_synapse synonym: "neurotransmission" RELATED [GOC:dph] synonym: "signal transmission across a synapse" BROAD [] synonym: "synaptic transmission" BROAD [] xref: Reactome:R-HSA-112316 "Neuronal System" xref: Reactome:R-HSA-442720 "CREB1 phosphorylation through the activation of Adenylate Cyclase" xref: Reactome:R-HSA-442729 "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde" xref: Reactome:R-HSA-442742 "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" xref: Reactome:R-HSA-451307 "Activation of Na-permeable kainate receptors" xref: Reactome:R-HSA-451308 "Activation of Ca-permeable Kainate Receptor" xref: Reactome:R-HSA-9619229 "Activation of RAC1 downstream of NMDARs" xref: Reactome:R-HSA-9619483 "Activation of AMPK downstream of NMDARs" xref: Reactome:R-HSA-9620244 "Long-term potentiation" xref: Wikipedia:Neurotransmission is_a: GO:0098916 ! anterograde trans-synaptic signaling relationship: RO:0000057 GO:0045202 ! has participant synapse [Term] id: GO:0007269 name: neurotransmitter secretion alt_id: GO:0010554 def: "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." [GOC:dph] comment: A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. subset: goslim_synapse synonym: "neurotransmitter release" EXACT [] synonym: "neurotransmitter secretory pathway" EXACT [] xref: Reactome:R-HSA-112310 "Neurotransmitter release cycle" is_a: GO:0006836 ! neurotransmitter transport is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099643 ! signal release from synapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: part_of GO:0007268 ! chemical synaptic transmission relationship: RO:0002338 GO:0098793 ! has target start location presynapse relationship: RO:0002339 GO:0043083 ! has target end location synaptic cleft [Term] id: GO:0007271 name: synaptic transmission, cholinergic def: "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, Wikipedia:Cholinergic] synonym: "cholinergic synaptic transmission" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission relationship: RO:0000057 CHEBI:15355 ! has participant acetylcholine [Term] id: GO:0007272 name: ensheathment of neurons def: "The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment." [GOC:dgh, GOC:dph, GOC:tb] synonym: "ionic insulation of neurons by glial cells" RELATED [] is_a: GO:0009987 ! cellular process relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007399 ! nervous system development relationship: RO:0000057 CL:0000125 ! has participant glial cell relationship: RO:0000057 CL:0000540 ! has participant neuron [Term] id: GO:0007274 name: neuromuscular synaptic transmission def: "The process of synaptic transmission from a neuron to a muscle, across a synapse." [GOC:dos, GOC:jl, MeSH:D009435] is_a: GO:0007268 ! chemical synaptic transmission [Term] id: GO:0007275 name: multicellular organism development namespace: biological_process def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] comment: Note that this term was 'developmental process'. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002295 UBERON:0000468 ! results in developmental progression of multicellular organism relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002295 UBERON:0000468 ! results in developmental progression of multicellular organism property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21234" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007276 name: gamete generation alt_id: GO:0009552 def: "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." [GOC:ems, GOC:mtg_sensu] synonym: "gametogenesis" RELATED [] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0019953 ! sexual reproduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007281 name: germ cell development def: "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators] synonym: "gametogenesis" NARROW [] synonym: "germ-cell development" EXACT [] synonym: "primordial germ cell development" NARROW [] xref: Reactome:R-HSA-9827857 "Specification of primordial germ cells" is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000586 ! results in development of germ cell relationship: part_of GO:0007276 ! gamete generation relationship: RO:0002296 CL:0000586 ! results in development of germ cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007283 name: spermatogenesis def: "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." [GOC:jid, ISBN:9780878933846, PMID:28073824, PMID:30990821] synonym: "generation of spermatozoa" EXACT systematic_synonym [] xref: Wikipedia:Spermatogenesis is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048232 ! male gamete generation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007284 name: spermatogonial cell division def: "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)." [GOC:bf, GOC:pr, ISBN:0879694238] comment: See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'. synonym: "spermatogonium division" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000020 ! has primary input spermatogonium relationship: part_of GO:0007283 ! spermatogenesis relationship: RO:0004009 CL:0000020 ! has primary input spermatogonium property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007285 name: primary spermatocyte growth def: "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." [GOC:jid, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000656 ! results in growth of primary spermatocyte relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0007283 ! spermatogenesis relationship: RO:0002343 CL:0000656 ! results in growth of primary spermatocyte property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007286 name: spermatid development def: "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." [GOC:dph, GOC:go_curators] synonym: "spermatid cell development" EXACT [] synonym: "spermiogenesis" EXACT [] xref: Wikipedia:Spermiogenesis is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000018 ! results in development of spermatid relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0048515 ! spermatid differentiation relationship: RO:0002296 CL:0000018 ! results in development of spermatid property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0007288 name: sperm axoneme assembly def: "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement." [GOC:bf, GOC:cilia, ISBN:0198547684] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035082 ! axoneme assembly intersection_of: GO:0035082 ! axoneme assembly intersection_of: BFO:0000066 CL:0000019 ! occurs in sperm relationship: BFO:0000066 CL:0000019 ! occurs in sperm relationship: part_of GO:0120316 ! sperm flagellum assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0007289 name: spermatid nucleus differentiation def: "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." [GOC:bf, GOC:dph, GOC:jl, GOC:mah] comment: See also the Cell Ontology term 'spermatid ; CL:0000018'. synonym: "spermatid nuclear differentiation" EXACT [] is_a: GO:0006997 ! nucleus organization relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0007286 ! spermatid development property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0007292 name: female gamete generation def: "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." [GOC:dph, ISBN:0198506732] is_a: GO:0007276 ! gamete generation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007293 name: germarium-derived egg chamber formation def: "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048477 ! oogenesis [Term] id: GO:0007308 name: oocyte construction alt_id: GO:0048110 def: "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:ems, GOC:mtg_sensu, GOC:tb, ISBN:0198506732] synonym: "oocyte arrangement" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048469 ! cell maturation intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002297 CL:0000023 ! results in formation of anatomical entity oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: RO:0002297 CL:0000023 ! results in formation of anatomical entity oocyte [Term] id: GO:0007309 name: oocyte axis specification alt_id: GO:0048111 def: "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] synonym: "oocyte axis determination" RELATED [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009798 ! axis specification intersection_of: GO:0009798 ! axis specification intersection_of: BFO:0000066 CL:0000023 ! occurs in oocyte relationship: BFO:0000066 CL:0000023 ! occurs in oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007308 ! oocyte construction [Term] id: GO:0007314 name: oocyte anterior/posterior axis specification alt_id: GO:0048112 def: "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] synonym: "oocyte anterior/posterior axis determination" EXACT [GOC:dph, GOC:tb] is_a: GO:0007309 ! oocyte axis specification is_a: GO:0009948 ! anterior/posterior axis specification intersection_of: GO:0009948 ! anterior/posterior axis specification intersection_of: BFO:0000066 CL:0000023 ! occurs in oocyte relationship: part_of GO:0008358 ! maternal determination of anterior/posterior axis, embryo [Term] id: GO:0007320 name: insemination def: "The introduction of semen or sperm into the genital tract of a female." [ISBN:0582227089] xref: Wikipedia:Insemination is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007620 ! copulation [Term] id: GO:0007338 name: single fertilization def: "The union of male and female gametes to form a zygote." [GOC:ems, GOC:mtg_sensu] synonym: "zygote biosynthesis" RELATED [] synonym: "zygote formation" RELATED [] xref: Reactome:R-HSA-1187000 "Fertilization" is_a: GO:0009566 ! fertilization relationship: in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:58024 [Term] id: GO:0007343 name: egg activation def: "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." [GOC:bf, PMID:9630751] xref: Wikipedia:Egg_activation is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000025 ! has primary input egg cell relationship: part_of GO:0007338 ! single fertilization relationship: RO:0004009 CL:0000025 ! has primary input egg cell [Term] id: GO:0007346 name: regulation of mitotic cell cycle def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "mitotic cell cycle modulation" EXACT [] synonym: "mitotic cell cycle regulation" EXACT [] synonym: "mitotic cell cycle regulator" RELATED [] synonym: "modulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: Reactome:R-HSA-2465910 "MASTL Facilitates Mitotic Progression" xref: Reactome:R-HSA-68911 "G2 Phase" is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000278 ! regulates mitotic cell cycle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0000278 ! regulates mitotic cell cycle [Term] id: GO:0007350 name: blastoderm segmentation def: "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0009880 ! embryonic pattern specification is_a: GO:0035282 ! segmentation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007351 name: tripartite regional subdivision def: "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions." [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0003002 ! regionalization relationship: part_of GO:0007350 ! blastoderm segmentation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007354 name: zygotic determination of anterior/posterior axis, embryo def: "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: BFO:0000066 CL:0000365 ! occurs in animal zygote relationship: BFO:0000066 CL:0000365 ! occurs in animal zygote property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007369 name: gastrulation def: "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846] subset: goslim_drosophila xref: Reactome:R-HSA-9758941 "Gastrulation" xref: Wikipedia:Gastrulation is_a: GO:0048598 ! embryonic morphogenesis relationship: has_part GO:0001705 ! ectoderm formation relationship: has_part GO:0001706 ! endoderm formation relationship: has_part GO:0001707 ! mesoderm formation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa [Term] id: GO:0007389 name: pattern specification process def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." [GOC:go_curators, GOC:isa_complete, ISBN:0521436125] subset: goslim_drosophila synonym: "pattern biosynthesis" RELATED [] synonym: "pattern formation" RELATED [] is_a: GO:0032501 ! multicellular organismal process relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0007275 ! multicellular organism development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007398 name: ectoderm development def: "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000924 ! results in development of ectoderm relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0000924 ! results in development of ectoderm [Term] id: GO:0007399 name: nervous system development def: "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh] subset: goslim_drosophila synonym: "pan-neural process" RELATED [] xref: Reactome:R-HSA-9675108 "Nervous system development" is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001016 ! results in development of nervous system relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0001016 ! results in development of nervous system [Term] id: GO:0007405 name: neuroblast proliferation alt_id: GO:0043349 alt_id: GO:0043350 def: "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000031 ! acts on population of neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048699 ! generation of neurons relationship: RO:0012003 CL:0000031 ! acts on population of neuroblast (sensu Vertebrata) [Term] id: GO:0007406 name: negative regulation of neuroblast proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai] synonym: "down regulation of neuroblast proliferation" EXACT [] synonym: "down-regulation of neuroblast proliferation" EXACT [] synonym: "downregulation of neuroblast proliferation" EXACT [] synonym: "inhibition of neuroblast proliferation" NARROW [] synonym: "suppression of neuroblast proliferation" EXACT [] is_a: GO:0050768 ! negative regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007405 ! negatively regulates neuroblast proliferation relationship: RO:0002212 GO:0007405 ! negatively regulates neuroblast proliferation [Term] id: GO:0007407 name: neuroblast activation alt_id: GO:0043351 alt_id: GO:0043352 def: "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048699 ! generation of neurons relationship: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) [Term] id: GO:0007409 name: axonogenesis alt_id: GO:0007410 def: "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells." [GOC:dph, GOC:jid, GOC:pg, GOC:pr, ISBN:0198506732] comment: Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon). synonym: "axon growth" NARROW [] synonym: "axon morphogenesis" EXACT [GOC:bf, PMID:23517308] synonym: "neuron long process generation" EXACT systematic_synonym [] is_a: GO:0048812 ! neuron projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0030424 ! results in morphogenesis of axon relationship: part_of GO:0048667 ! cell morphogenesis involved in neuron differentiation relationship: part_of GO:0061564 ! axon development relationship: RO:0002298 GO:0030424 ! results in morphogenesis of axon [Term] id: GO:0007416 name: synapse assembly def: "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." [GOC:mah] subset: goslim_synapse synonym: "synapse biogenesis" EXACT [GOC:mah] synonym: "synaptogenesis" EXACT [GOC:mah] xref: Wikipedia:Synaptogenesis is_a: GO:0034329 ! cell junction assembly is_a: GO:0050808 ! synapse organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0045202 ! results in assembly of synapse relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002588 GO:0045202 ! results in assembly of synapse [Term] id: GO:0007417 name: central nervous system development def: "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GOC:bf, GOC:jid, ISBN:0582227089] synonym: "CNS development" EXACT [] xref: Wikipedia:Neural_development is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001017 ! results in development of central nervous system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002296 UBERON:0001017 ! results in development of central nervous system [Term] id: GO:0007420 name: brain development def: "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000955 ! results in development of brain relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007417 ! central nervous system development relationship: part_of GO:0060322 ! head development relationship: RO:0002296 UBERON:0000955 ! results in development of brain [Term] id: GO:0007422 name: peripheral nervous system development def: "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000010 ! results in development of peripheral nervous system relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002296 UBERON:0000010 ! results in development of peripheral nervous system [Term] id: GO:0007423 name: sensory organ development def: "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators] subset: goslim_drosophila synonym: "sense organ development" EXACT [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000020 ! results in development of sense organ relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0000020 ! results in development of sense organ [Term] id: GO:0007439 name: ectodermal digestive tract development def: "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." [GOC:curators] synonym: "ectodermal gut development" RELATED [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002297 UBERON:0004906 ! results in formation of anatomical entity ectodermal part of digestive tract relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048565 ! digestive tract development relationship: RO:0002297 UBERON:0004906 ! results in formation of anatomical entity ectodermal part of digestive tract [Term] id: GO:0007440 name: foregut morphogenesis def: "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001041 ! results in morphogenesis of foregut relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: RO:0002298 UBERON:0001041 ! results in morphogenesis of foregut [Term] id: GO:0007442 name: hindgut morphogenesis def: "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001046 ! results in morphogenesis of hindgut relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: part_of GO:0061525 ! hindgut development relationship: RO:0002298 UBERON:0001046 ! results in morphogenesis of hindgut [Term] id: GO:0007492 name: endoderm development def: "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000925 ! results in development of endoderm relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0000925 ! results in development of endoderm [Term] id: GO:0007494 name: midgut development def: "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." [GOC:jid, UBERON:0001045] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001045 ! results in development of midgut relationship: RO:0002296 UBERON:0001045 ! results in development of midgut [Term] id: GO:0007498 name: mesoderm development def: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb] subset: goslim_drosophila is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000926 ! results in development of mesoderm relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0000926 ! results in development of mesoderm [Term] id: GO:0007506 name: gonadal mesoderm development def: "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003855 ! results in development of gonad mesenchyme relationship: part_of GO:0008406 ! gonad development relationship: RO:0002296 UBERON:0003855 ! results in development of gonad mesenchyme [Term] id: GO:0007507 name: heart development alt_id: GO:0007511 def: "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948] synonym: "cardiac development" RELATED [] synonym: "dorsal vessel development" NARROW [] xref: Wikipedia:Heart_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007100 ! results in development of primary circulatory organ relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0072359 ! circulatory system development relationship: RO:0002296 UBERON:0007100 ! results in development of primary circulatory organ [Term] id: GO:0007517 name: muscle organ development def: "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732] is_a: GO:0048513 ! animal organ development is_a: GO:0061061 ! muscle structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001630 ! results in development of muscle organ relationship: RO:0002296 UBERON:0001630 ! results in development of muscle organ [Term] id: GO:0007519 name: skeletal muscle tissue development alt_id: GO:0048637 def: "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." [GOC:mtg_muscle] synonym: "myogenesis" RELATED [] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001134 ! results in development of skeletal muscle tissue relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060538 ! skeletal muscle organ development relationship: RO:0002296 UBERON:0001134 ! results in development of skeletal muscle tissue [Term] id: GO:0007528 name: neuromuscular junction development def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." [GOC:mtg_OBO2OWL_2013] synonym: "neuromuscular junction organization" EXACT [] synonym: "neuromuscular junction stability" RELATED [GOC:pr] synonym: "NMJ stability" RELATED [GOC:pr] is_a: GO:0050808 ! synapse organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031594 ! results in organization of neuromuscular junction relationship: RO:0002592 GO:0031594 ! results in organization of neuromuscular junction [Term] id: GO:0007548 name: sex differentiation namespace: biological_process def: "The establishment of the sex of an organism by physical differentiation." [GOC:ai] xref: Wikipedia:Sexual_differentiation is_a: GO:0003006 ! developmental process involved in reproduction [Term] id: GO:0007565 name: female pregnancy namespace: biological_process def: "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." [ISBN:0192800825] subset: goslim_chembl synonym: "carrying of young" RELATED [] synonym: "gestation" EXACT [] xref: Wikipedia:Gestation is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process relationship: in_taxon NCBITaxon:40674 ! Mammalia [Term] id: GO:0007566 name: embryo implantation def: "Attachment of the blastocyst to the uterine lining." [GOC:isa_complete, PMID:10882512] synonym: "blastocyst implantation" EXACT [] is_a: GO:0022414 ! reproductive process relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0007275 ! multicellular organism development relationship: part_of GO:0007565 ! female pregnancy [Term] id: GO:0007585 name: respiratory gaseous exchange by respiratory system def: "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [ISBN:0198506732] subset: goslim_chembl synonym: "breathing" BROAD [] synonym: "respiration" BROAD [] is_a: GO:0032501 ! multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007586 name: digestion def: "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, ISBN:0198506732] subset: goslim_chembl subset: goslim_pir xref: Reactome:R-HSA-8935690 "Digestion" xref: Wikipedia:Digestion is_a: GO:0032501 ! multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007588 name: excretion def: "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." [ISBN:0192801023] subset: gocheck_do_not_annotate subset: goslim_pir xref: Wikipedia:Excretion is_a: GO:0003008 ! system process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0007589 name: body fluid secretion namespace: biological_process def: "The controlled release of a fluid by a cell or tissue in an animal." [GOC:ai, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0046903 ! secretion is_a: GO:0050878 ! regulation of body fluid levels [Term] id: GO:0007591 name: molting cycle, chitin-based cuticle namespace: biological_process def: "The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster." [GOC:jl, GOC:mtg_sensu] synonym: "chitin-based cuticle molting cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0042303 ! molting cycle [Term] id: GO:0007595 name: lactation namespace: biological_process def: "The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young." [ISBN:0198506732] synonym: "milk secretion" EXACT [GOC:pr] xref: Wikipedia:Lactation is_a: GO:0007589 ! body fluid secretion relationship: has_part GO:0060156 ! milk ejection reflex relationship: part_of GO:0030879 ! mammary gland development [Term] id: GO:0007600 name: sensory perception def: "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai, GOC:dph] subset: goslim_drosophila xref: Reactome:R-HSA-9709957 "Sensory Perception" xref: Wikipedia:Perception is_a: GO:0050877 ! nervous system process [Term] id: GO:0007601 name: visual perception def: "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." [GOC:ai] synonym: "sense of sight" EXACT [] synonym: "sensory visual perception" EXACT [] synonym: "vision" EXACT [] xref: Wikipedia:Visual_perception is_a: GO:0050953 ! sensory perception of light stimulus [Term] id: GO:0007605 name: sensory perception of sound def: "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." [GOC:ai] synonym: "hearing" EXACT [] synonym: "perception of sound" EXACT [] xref: Reactome:R-HSA-9659379 "Sensory processing of sound" xref: Wikipedia:Hearing_(sense) is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0007606 name: sensory perception of chemical stimulus def: "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "chemosensory perception" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0007608 name: sensory perception of smell def: "The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process." [GOC:ai] synonym: "olfaction" EXACT [] synonym: "scent perception" EXACT [] synonym: "sense of smell" EXACT [] synonym: "smell perception" EXACT [] xref: Wikipedia:Olfaction is_a: GO:0007606 ! sensory perception of chemical stimulus [Term] id: GO:0007610 name: behavior alt_id: GO:0023032 alt_id: GO:0044708 alt_id: GO:0044709 def: "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973] comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.\n2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis). subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_flybase_ribbon synonym: "behavioral response to stimulus" EXACT [] synonym: "behaviour" EXACT [] synonym: "behavioural response to stimulus" EXACT [] synonym: "single-organism behavior" RELATED [] xref: Wikipedia:Behavior is_a: GO:0032501 ! multicellular organismal process disjoint_from: GO:0032502 ! developmental process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002608 UBERON:0001016 ! process has causal agent nervous system created_by: jl creation_date: 2012-09-20T14:06:08Z [Term] id: GO:0007611 name: learning or memory def: "The acquisition and processing of information and/or the storage and retrieval of this information over time." [GOC:jid, PMID:8938125] is_a: GO:0007610 ! behavior is_a: GO:0050890 ! cognition [Term] id: GO:0007613 name: memory def: "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." [GOC:curators, ISBN:0582227089] xref: Wikipedia:Memory is_a: GO:0007611 ! learning or memory [Term] id: GO:0007617 name: mating behavior def: "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." [GOC:ai, GOC:dph] synonym: "mating behaviour" EXACT [] xref: Wikipedia:Mating_behaviour is_a: GO:0019098 ! reproductive behavior [Term] id: GO:0007620 name: copulation def: "The act of sexual union between male and female, involving the transfer of sperm." [ISBN:0721662544] is_a: GO:0007617 ! mating behavior [Term] id: GO:0007626 name: locomotory behavior def: "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph] subset: goslim_drosophila synonym: "behavior via locomotion" EXACT [] synonym: "locomotion in response to stimulus" EXACT [] synonym: "locomotory behavioral response to stimulus" EXACT [] synonym: "locomotory behaviour" EXACT [] synonym: "locomotory behavioural response to stimulus" EXACT [] is_a: GO:0007610 ! behavior [Term] id: GO:0008015 name: blood circulation alt_id: GO:0070261 def: "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:mtg_heart, ISBN:0192800825] subset: goslim_pir synonym: "hemolymph circulation" RELATED [] is_a: GO:0003013 ! circulatory system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0008016 name: regulation of heart contraction def: "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of cardiac contraction" EXACT [] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060047 ! regulates heart contraction relationship: RO:0002211 GO:0060047 ! regulates heart contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0008028 name: monocarboxylic acid transmembrane transporter activity alt_id: GO:0008505 def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai] synonym: "monocarboxylate carrier" NARROW [] synonym: "prostaglandin/thromboxane transporter activity" NARROW [] xref: Reactome:R-HSA-429749 "SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-433698 "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-9645220 "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol" is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:25384 ! has primary input monocarboxylic acid relationship: part_of GO:0015718 ! monocarboxylic acid transport relationship: RO:0004009 CHEBI:25384 ! has primary input monocarboxylic acid [Term] id: GO:0008078 name: mesodermal cell migration def: "The orderly movement of mesodermal cells from one site to another." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047] synonym: "mesoderm cell migration" EXACT [] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000222 ! results in movement of mesodermal cell relationship: RO:0002565 CL:0000222 ! results in movement of mesodermal cell property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0008088 name: axo-dendritic transport def: "The directed movement of organelles or molecules along microtubules in neuron projections." [ISBN:0815316194] subset: goslim_synapse synonym: "axon cargo transport" NARROW [] synonym: "axonal transport" NARROW [] synonym: "axoplasmic transport" NARROW [] xref: Wikipedia:Axoplasmic_transport is_a: GO:0010970 ! transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: BFO:0000066 GO:0043005 ! occurs in neuron projection intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule relationship: BFO:0000066 GO:0043005 ! occurs in neuron projection relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0008089 name: anterograde axonal transport def: "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." [ISBN:0815316194] subset: goslim_synapse synonym: "anterograde axon cargo transport" EXACT [] is_a: GO:0098930 ! axonal transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm intersection_of: RO:0002339 GO:0098793 ! has target end location presynapse intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule relationship: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm relationship: RO:0002339 GO:0098793 ! has target end location presynapse [Term] id: GO:0008090 name: retrograde axonal transport def: "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons." [ISBN:0815316194] subset: goslim_synapse synonym: "retrograde axon cargo transport" EXACT [] is_a: GO:0098930 ! axonal transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm intersection_of: RO:0002338 GO:0098793 ! has target start location presynapse intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule relationship: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm relationship: RO:0002338 GO:0098793 ! has target start location presynapse [Term] id: GO:0008104 name: intracellular protein localization alt_id: GO:0008105 alt_id: GO:0016249 alt_id: GO:0034613 def: "Any process in which a protein is transported to, or maintained in, a specific location." [GOC:ai] subset: goslim_drosophila synonym: "asymmetric protein localisation" RELATED [GOC:mah] synonym: "asymmetric protein localization" RELATED [] synonym: "cellular protein localisation" EXACT [GOC:mah] synonym: "cellular protein localization" EXACT [] synonym: "channel localizer activity" NARROW [GOC:mah] synonym: "establishment and maintenance of asymmetric protein localization" RELATED [] synonym: "establishment and maintenance of protein localization" RELATED [] synonym: "protein localisation" EXACT [GOC:mah] synonym: "protein localization" BROAD [] xref: Reactome:R-HSA-9609507 "Protein localization" is_a: GO:0033036 ! macromolecule localization relationship: RO:0004009 PR:000000001 ! has primary input protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0008150 name: biological process name: biological_process namespace: biological_process alt_id: GO:0000004 alt_id: GO:0007582 alt_id: GO:0044699 def: "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast synonym: "biological process" EXACT [] synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process is_a: http://rs.tdwg.org/dwc/terms/Event ! Event relationship: has_part GO:0003674 ! molecular_function property_value: IAO:0000111 "biological_process" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl created_by: jl creation_date: 2012-09-19T15:05:24Z [Term] id: GO:0008152 name: metabolic process alt_id: GO:0044236 alt_id: GO:0044710 def: "A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote_ribbon synonym: "metabolism" EXACT [] xref: Reactome:R-HSA-1430728 "Metabolism" xref: Wikipedia:Metabolism is_a: GO:0009987 ! cellular process disjoint_from: GO:0051179 ! localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28932" xsd:anyURI created_by: jl creation_date: 2012-10-17T15:46:40Z [Term] id: GO:0008202 name: steroid metabolic process def: "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [ISBN:0198547684] synonym: "steroid metabolism" EXACT [] xref: Reactome:R-HSA-8957322 "Metabolism of steroids" xref: Wikipedia:Steroid_metabolism is_a: GO:0006629 ! lipid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35341 ! has primary input or output steroid relationship: RO:0004007 CHEBI:35341 ! has primary input or output steroid [Term] id: GO:0008206 name: bile acid metabolic process def: "The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:go_curators] synonym: "bile acid metabolism" EXACT [] xref: Reactome:R-HSA-194068 "Bile acid and bile salt metabolism" is_a: GO:0008202 ! steroid metabolic process is_a: GO:0032787 ! monocarboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:36235 ! has primary input or output bile acid anion relationship: RO:0004007 CHEBI:36235 ! has primary input or output bile acid anion [Term] id: GO:0008219 name: cell death def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] is_a: GO:0009987 ! cellular process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24680" xsd:anyURI [Term] id: GO:0008283 name: cell population proliferation def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb] comment: This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms. subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "cell proliferation" RELATED [] is_a: GO:0009987 ! cellular process property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008284 name: positive regulation of cell population proliferation def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators] synonym: "activation of cell proliferation" NARROW [] synonym: "positive regulation of cell proliferation" RELATED [] synonym: "stimulation of cell proliferation" NARROW [] synonym: "up regulation of cell proliferation" EXACT [] synonym: "up-regulation of cell proliferation" EXACT [] synonym: "upregulation of cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008283 ! positively regulates cell population proliferation relationship: RO:0002213 GO:0008283 ! positively regulates cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008285 name: negative regulation of cell population proliferation def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] synonym: "down regulation of cell proliferation" EXACT [] synonym: "down-regulation of cell proliferation" EXACT [] synonym: "downregulation of cell proliferation" EXACT [] synonym: "inhibition of cell proliferation" NARROW [] synonym: "negative regulation of cell proliferation" RELATED [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008283 ! negatively regulates cell population proliferation relationship: RO:0002212 GO:0008283 ! negatively regulates cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008291 name: acetylcholine metabolic process def: "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752] synonym: "acetylcholine metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:15355 ! has primary input or output acetylcholine relationship: RO:0004007 CHEBI:15355 ! has primary input or output acetylcholine [Term] id: GO:0008292 name: acetylcholine biosynthetic process def: "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine anabolism" EXACT [] synonym: "acetylcholine biosynthesis" EXACT [] synonym: "acetylcholine formation" EXACT [] synonym: "acetylcholine synthesis" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:15355 ! has primary output acetylcholine relationship: RO:0004008 CHEBI:15355 ! has primary output acetylcholine [Term] id: GO:0008320 name: protein transmembrane transporter activity alt_id: GO:0015266 alt_id: GO:0015463 def: "Enables the transfer of a protein from one side of a membrane to the other." [GOC:jl] synonym: "protein channel activity" RELATED [] xref: Reactome:R-HSA-1268022 "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space" xref: Reactome:R-HSA-1299475 "TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix" xref: Reactome:R-HSA-184269 "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex" xref: Reactome:R-HSA-3149434 "Transport of GAG to the Plasma Membrane" xref: Reactome:R-HSA-5205661 "Pink1 is recruited from the cytoplasm to the mitochondria" xref: Reactome:R-HSA-5210943 "pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5210947 "pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5228406 "tetX HC transports tetX LC from target cell endosome membrane into cytosol" xref: Reactome:R-HSA-5229111 "AP4 transports APP from trans-Golgi network to endosome lumen" xref: Reactome:R-HSA-5244404 "botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244428 "botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244506 "botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5246514 "botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol" xref: Reactome:R-HSA-5250616 "botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250884 "botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250972 "botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5336420 "DT fragment B transports DT fragment A from target cell endosome membrane" xref: Reactome:R-HSA-9636375 "SecA2 transports SapM from cytoplasm to cytosol" xref: Reactome:R-HSA-9698930 "HCMV C Nucleocapsid Translocation" xref: Reactome:R-HSA-9698933 "HCMV B Nucleocapsid Translocation" xref: Reactome:R-HSA-9760705 "GspD2:GspC2:GspS2 transports LT from periplasmic to extracellular space" is_a: GO:0022884 ! macromolecule transmembrane transporter activity is_a: GO:0042887 ! amide transmembrane transporter activity is_a: GO:0140318 ! protein transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: part_of GO:0071806 {source="GO_REF:0000090"} ! protein transmembrane transport [Term] id: GO:0008324 name: monoatomic cation transmembrane transporter activity def: "Enables the transfer of cation from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "cation transmembrane transporter activity" BROAD [] synonym: "transmembrane cation transporter activity" EXACT [] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation relationship: part_of GO:0098655 ! monoatomic cation transmembrane transport relationship: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0008347 name: glial cell migration alt_id: GO:0043359 def: "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:jl, GOC:mtg_sensu] synonym: "glia cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000125 ! results in movement of glial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042063 ! gliogenesis relationship: RO:0002565 CL:0000125 ! results in movement of glial cell [Term] id: GO:0008354 name: germ cell migration def: "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl] synonym: "germ-cell migration" EXACT [] synonym: "pole cell migration" NARROW [] synonym: "primordial germ cell migration" RELATED [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000586 ! results in movement of germ cell relationship: part_of GO:0007276 ! gamete generation relationship: RO:0002565 CL:0000586 ! results in movement of germ cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008356 name: asymmetric cell division def: "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] synonym: "asymmetric cytokinesis" RELATED [] synonym: "asymmetrical cell division" EXACT [] synonym: "asymmetrical cytokinesis" RELATED [] xref: Wikipedia:Asymmetric_cell_division is_a: GO:0051301 ! cell division [Term] id: GO:0008358 name: maternal determination of anterior/posterior axis, embryo def: "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0008361 name: regulation of cell size def: "Any process that modulates the size of a cell." [GOC:go_curators] synonym: "cell size control" EXACT [] is_a: GO:0032535 ! regulation of cellular component size [Term] id: GO:0008366 name: axon ensheathment alt_id: GO:0042553 def: "Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal." [GOC:jl, ISBN:0878932437] synonym: "cellular axon ensheathment" EXACT [] synonym: "cellular nerve ensheathment" RELATED [] synonym: "nerve ensheathment" RELATED [] is_a: GO:0007272 ! ensheathment of neurons relationship: RO:0000057 GO:0030424 ! has participant axon [Term] id: GO:0008406 name: gonad development def: "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." [GOC:ems, ISBN:0198506732] synonym: "gonadogenesis" EXACT [GOC:cjm] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000991 ! results in development of gonad relationship: part_of GO:0045137 ! development of primary sexual characteristics relationship: RO:0002296 UBERON:0000991 ! results in development of gonad property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0008504 name: monoamine transmembrane transporter activity alt_id: GO:0015201 def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah] xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles" xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+, Cl- from extracellular region to cytosol" xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles" xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse" xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol" is_a: GO:0022804 ! active transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:63534 ! has primary input monoamine relationship: part_of GO:0015844 ! monoamine transport relationship: RO:0004009 CHEBI:63534 ! has primary input monoamine [Term] id: GO:0008544 name: epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003] synonym: "hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0009888 ! tissue development property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0008584 name: male gonad development def: "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." [GOC:jid] synonym: "testicular development" EXACT [GOC:sl] synonym: "testis development" EXACT [GOC:sl] xref: Reactome:R-HSA-9690406 "Transcriptional regulation of testis differentiation" is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000473 ! results in development of testis relationship: part_of GO:0046546 ! development of primary male sexual characteristics relationship: RO:0002296 UBERON:0000473 ! results in development of testis property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0008585 name: female gonad development alt_id: GO:0061039 def: "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:tb] synonym: "ovarian development" RELATED [GOC:sl] synonym: "ovary development" RELATED [GOC:sl] is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000992 ! results in development of ovary relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0046545 ! development of primary female sexual characteristics relationship: RO:0002296 UBERON:0000992 ! results in development of ovary [Term] id: GO:0008594 name: photoreceptor cell morphogenesis def: "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." [GOC:jid, GOC:mah] synonym: "photoreceptor development" RELATED [] is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000210 ! results in morphogenesis of photoreceptor cell relationship: part_of GO:0042461 ! photoreceptor cell development relationship: RO:0002298 CL:0000210 ! results in morphogenesis of photoreceptor cell [Term] id: GO:0008595 name: anterior/posterior axis specification, embryo def: "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] synonym: "anterior/posterior axis determination, embryo" RELATED [GOC:dph] is_a: GO:0000578 ! embryonic axis specification is_a: GO:0009948 ! anterior/posterior axis specification relationship: part_of GO:0007351 ! tripartite regional subdivision property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0008610 name: lipid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid anabolism" EXACT [] synonym: "lipid biosynthesis" EXACT [] synonym: "lipid formation" EXACT [] synonym: "lipid synthesis" EXACT [] synonym: "lipogenesis" EXACT [GOC:sl] is_a: GO:0006629 ! lipid metabolic process is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18059 ! has primary output lipid relationship: RO:0004008 CHEBI:18059 ! has primary output lipid [Term] id: GO:0008643 name: carbohydrate transport alt_id: GO:0006861 alt_id: GO:0008644 def: "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y." [GOC:ai] subset: goslim_pir subset: goslim_yeast synonym: "sugar transport" NARROW [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0008645 name: hexose transmembrane transport alt_id: GO:0008646 alt_id: GO:0008647 alt_id: GO:0035428 def: "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "hexose membrane transport" RELATED [] synonym: "hexose transport" RELATED [] synonym: "high-affinity hexose transport" NARROW [] synonym: "low-affinity hexose transport" NARROW [] xref: Reactome:R-HSA-189200 "Cellular hexose transport" is_a: GO:0015749 ! monosaccharide transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: RO:0004009 CHEBI:18133 ! has primary input hexose created_by: bf creation_date: 2010-04-08T10:27:23Z [Term] id: GO:0008652 name: amino acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732] synonym: "amino acid anabolism" EXACT [] synonym: "amino acid biosynthesis" EXACT [] synonym: "amino acid formation" EXACT [] synonym: "amino acid synthesis" EXACT [] synonym: "cellular amino acid biosynthetic process" EXACT [] xref: Wikipedia:Amino_acid_synthesis is_a: GO:0006520 ! amino acid metabolic process is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35238 ! has primary output amino-acid zwitterion relationship: RO:0004008 CHEBI:35238 ! has primary output amino-acid zwitterion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27304" xsd:anyURI [Term] id: GO:0009056 name: catabolic process alt_id: GO:0044243 alt_id: GO:0044712 def: "A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684] subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_chembl subset: goslim_plant subset: goslim_plant_ribbon synonym: "breakdown of chemical" EXACT [] synonym: "breakdown of molecule" EXACT [] synonym: "breakdown of substance" EXACT [] synonym: "catabolism" EXACT [] synonym: "cellular breakdown" EXACT [] synonym: "cellular catabolism" EXACT [] synonym: "cellular degradation" EXACT [] synonym: "degradation" EXACT [] xref: Wikipedia:Catabolism is_a: GO:0008152 ! metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28921" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28932" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29627" xsd:anyURI created_by: jl creation_date: 2012-10-17T15:52:35Z [Term] id: GO:0009057 name: macromolecule catabolic process alt_id: GO:0043285 alt_id: GO:0044266 def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "cellular macromolecule catabolic process" RELATED [] synonym: "cellular macromolecule catabolism" RELATED [] synonym: "cellular macromolecule degradation" RELATED [] synonym: "macromolecule breakdown" EXACT [] synonym: "macromolecule catabolism" EXACT [] synonym: "macromolecule degradation" EXACT [] synonym: "multicellular organismal macromolecule catabolic process" NARROW [] is_a: GO:0009056 ! catabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule relationship: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule [Term] id: GO:0009058 name: biosynthetic process alt_id: GO:0044274 alt_id: GO:0044711 def: "A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant subset: goslim_plant_ribbon synonym: "anabolism" EXACT [] synonym: "biosynthesis" EXACT [] synonym: "formation" BROAD [] synonym: "multicellular organismal biosynthetic process" NARROW [] synonym: "single-organism biosynthetic process" RELATED [] synonym: "synthesis" EXACT [] xref: Wikipedia:Anabolism is_a: GO:0008152 ! metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28932" xsd:anyURI created_by: jl creation_date: 2012-10-17T15:52:18Z [Term] id: GO:0009059 name: macromolecule biosynthetic process alt_id: GO:0043284 def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule anabolism" EXACT [] synonym: "macromolecule biosynthesis" EXACT [] synonym: "macromolecule formation" EXACT [] synonym: "macromolecule synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33694 ! has primary output biomacromolecule relationship: RO:0004008 CHEBI:33694 ! has primary output biomacromolecule property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15249" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25418" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI [Term] id: GO:0009063 name: amino acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai] synonym: "amino acid breakdown" EXACT [] synonym: "amino acid catabolism" EXACT [] synonym: "amino acid degradation" EXACT [] synonym: "cellular amino acid catabolic process" EXACT [] is_a: GO:0006520 ! amino acid metabolic process is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion relationship: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0009100 name: glycoprotein metabolic process def: "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] subset: goslim_drosophila synonym: "glycoprotein metabolism" EXACT [] is_a: GO:0019538 ! protein metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:17089 ! has primary input or output glycoprotein relationship: RO:0004007 CHEBI:17089 ! has primary input or output glycoprotein [Term] id: GO:0009101 name: glycoprotein biosynthetic process def: "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [PMID:35536965] subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "glycoprotein anabolism" EXACT [] synonym: "glycoprotein biosynthesis" EXACT [] synonym: "glycoprotein formation" EXACT [] synonym: "glycoprotein synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:17089 ! has primary output glycoprotein relationship: RO:0004008 CHEBI:17089 ! has primary output glycoprotein [Term] id: GO:0009112 name: nucleobase metabolic process def: "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma] synonym: "nucleobase metabolism" EXACT [] is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18282 ! has primary input or output nucleobase relationship: RO:0004007 CHEBI:18282 ! has primary input or output nucleobase [Term] id: GO:0009250 name: glucan biosynthetic process def: "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan anabolism" EXACT [] synonym: "glucan biosynthesis" EXACT [] synonym: "glucan formation" EXACT [] synonym: "glucan synthesis" EXACT [] is_a: GO:0000271 ! polysaccharide biosynthetic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:37163 ! has primary output glucan relationship: RO:0004008 CHEBI:37163 ! has primary output glucan [Term] id: GO:0009251 name: glucan catabolic process def: "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan breakdown" EXACT [] synonym: "glucan catabolism" EXACT [] synonym: "glucan degradation" EXACT [] is_a: GO:0000272 ! polysaccharide catabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:37163 ! has primary input glucan relationship: RO:0004009 CHEBI:37163 ! has primary input glucan [Term] id: GO:0009306 name: protein secretion alt_id: GO:0045166 alt_id: GO:0045731 def: "The controlled release of proteins from a cell." [GOC:ai] synonym: "glycoprotein secretion" NARROW [] synonym: "protein secretion during cell fate commitment" NARROW [] synonym: "protein secretion resulting in cell fate commitment" NARROW [] is_a: GO:0015031 ! protein transport is_a: GO:0032940 ! secretion by cell is_a: GO:0035592 ! establishment of protein localization to extracellular region is_a: GO:0071692 ! protein localization to extracellular region intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0009308 name: amine metabolic process alt_id: GO:0044106 def: "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] subset: goslim_chembl subset: goslim_pir synonym: "amine metabolism" EXACT [] synonym: "cellular amine metabolic process" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:32952 ! has primary input or output amine relationship: RO:0004007 CHEBI:32952 ! has primary input or output amine created_by: jl creation_date: 2009-07-15T11:55:44Z [Term] id: GO:0009309 name: amine biosynthetic process def: "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine anabolism" EXACT [] synonym: "amine biosynthesis" EXACT [] synonym: "amine formation" EXACT [] synonym: "amine synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0009308 ! amine metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:32952 ! has primary output amine relationship: RO:0004008 CHEBI:32952 ! has primary output amine [Term] id: GO:0009310 name: amine catabolic process def: "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine breakdown" EXACT [] synonym: "amine catabolism" EXACT [] synonym: "amine degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0009308 ! amine metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0009314 name: response to radiation def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:jl, Wikipedia:Electromagnetic_radiation] comment: Note that 'radiation' refers to electromagnetic radiation of any wavelength. synonym: "response to electromagnetic radiation stimulus" EXACT [] synonym: "response to radiation stimulus" EXACT [] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0009415 name: response to water def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." [GOC:jl] synonym: "response to water stimulus" EXACT [GOC:dos] is_a: GO:0001101 ! response to acid chemical is_a: GO:0009628 ! response to abiotic stimulus is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:15377 ! has primary input water relationship: RO:0004009 CHEBI:15377 ! has primary input water [Term] id: GO:0009416 name: response to light stimulus def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:go_curators, ISBN:0582227089] subset: goslim_plant is_a: GO:0009314 ! response to radiation intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:30212 ! has primary input photon relationship: RO:0004009 CHEBI:30212 ! has primary input photon [Term] id: GO:0009566 name: fertilization def: "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:tb, ISBN:0198506732] synonym: "syngamy" EXACT [] xref: Wikipedia:Fertilisation is_a: GO:0022414 ! reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: RO:0002297 CL:0010017 ! results in formation of anatomical entity zygote intersection_of: RO:0012008 GO:0043073 ! results in fusion of germ cell nucleus relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0019953 ! sexual reproduction relationship: RO:0002297 CL:0010017 ! results in formation of anatomical entity zygote relationship: RO:0012008 GO:0043073 ! results in fusion of germ cell nucleus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20176" xsd:anyURI [Term] id: GO:0009581 name: detection of external stimulus def: "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." [GOC:hb] synonym: "perception of external stimulus" RELATED [] is_a: GO:0009605 ! response to external stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009582 name: detection of abiotic stimulus def: "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." [GOC:hb] synonym: "perception of abiotic stimulus" RELATED [] is_a: GO:0009628 ! response to abiotic stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009583 name: detection of light stimulus def: "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." [GOC:go_curators] synonym: "detection of light" EXACT [] synonym: "perception of light" RELATED [] is_a: GO:0009416 ! response to light stimulus is_a: GO:0009581 ! detection of external stimulus is_a: GO:0009582 ! detection of abiotic stimulus [Term] id: GO:0009584 name: detection of visible light def: "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732] synonym: "perception of visible light" RELATED [] is_a: GO:0009583 ! detection of light stimulus [Term] id: GO:0009593 name: detection of chemical stimulus def: "The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal." [GOC:jl] synonym: "chemoperception" EXACT [] synonym: "chemoreception" RELATED [] synonym: "detection of chemical substance" EXACT [] synonym: "perception of chemical stimulus" RELATED [] synonym: "perception of chemical substance" RELATED [] is_a: GO:0051606 ! detection of stimulus relationship: part_of GO:0042221 ! response to chemical [Term] id: GO:0009605 name: response to external stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_drosophila subset: goslim_plant synonym: "response to environmental stimulus" EXACT [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009607 name: response to biotic stimulus def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_metagenomics subset: goslim_plant synonym: "response to biotic stress" NARROW [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009612 name: response to mechanical stimulus def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus." [GOC:hb] synonym: "chemi-mechanical coupling" RELATED [] synonym: "mechanical stimulus response" EXACT [] is_a: GO:0009605 ! response to external stimulus is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0009620 name: response to fungus alt_id: GO:0009621 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." [GOC:hb] synonym: "response to fungi" EXACT [] is_a: GO:0051707 ! response to other organism intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 NCBITaxon:4751 ! has primary input Fungi relationship: RO:0004009 NCBITaxon:4751 ! has primary input Fungi property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0009628 name: response to abiotic stimulus def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_metagenomics subset: goslim_plant synonym: "response to abiotic stress" NARROW [] is_a: GO:0050896 ! response to stimulus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16572" xsd:anyURI [Term] id: GO:0009636 name: response to toxic substance def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:lr] subset: goslim_chembl synonym: "detoxification response" NARROW [] synonym: "toxin resistance" RELATED [] synonym: "toxin susceptibility/resistance" RELATED [] is_a: GO:0042221 ! response to chemical [Term] id: GO:0009653 name: anatomical structure morphogenesis def: "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." [GOC:go_curators, ISBN:0521436125] synonym: "anatomical structure organization" EXACT [] synonym: "embryogenesis and morphogenesis" BROAD [] synonym: "morphogenesis" EXACT [] xref: Wikipedia:Morphogenesis is_a: GO:0032502 ! developmental process disjoint_from: GO:0048856 ! anatomical structure development disjoint_from: GO:0071695 ! anatomical structure maturation relationship: part_of GO:0048856 ! anatomical structure development [Term] id: GO:0009712 name: catechol-containing compound metabolic process def: "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." [GOC:sm, ISBN:0198547684] synonym: "catechol metabolic process" RELATED [] synonym: "catechol metabolism" RELATED [] is_a: GO:0018958 ! phenol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33566 ! has primary input or output catechols relationship: RO:0004007 CHEBI:33566 ! has primary input or output catechols [Term] id: GO:0009713 name: catechol-containing compound biosynthetic process def: "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] synonym: "catechol anabolism" RELATED [] synonym: "catechol biosynthesis" RELATED [] synonym: "catechol biosynthetic process" RELATED [] synonym: "catechol formation" RELATED [] synonym: "catechol synthesis" RELATED [] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0046189 ! phenol-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33566 ! has primary output catechols relationship: RO:0004008 CHEBI:33566 ! has primary output catechols [Term] id: GO:0009719 name: response to endogenous stimulus def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:sm] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_plant is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009725 name: response to hormone def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:jl] synonym: "growth regulator" RELATED [] synonym: "response to hormone stimulus" EXACT [GOC:dos] is_a: GO:0009719 ! response to endogenous stimulus is_a: GO:0042221 ! response to chemical property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0009743 name: response to carbohydrate def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:jl] synonym: "response to carbohydrate stimulus" EXACT [GOC:dos] is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0009746 name: response to hexose def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:jl] synonym: "response to hexose stimulus" EXACT [GOC:dos] is_a: GO:0034284 ! response to monosaccharide intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: RO:0004009 CHEBI:18133 ! has primary input hexose [Term] id: GO:0009749 name: response to glucose def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:jl] synonym: "response to glucose stimulus" EXACT [GOC:dos] is_a: GO:0009746 ! response to hexose intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose relationship: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose [Term] id: GO:0009786 name: regulation of asymmetric cell division def: "Any process that modulates the frequency, rate or extent of asymmetric cell division." [GOC:lr] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008356 ! regulates asymmetric cell division relationship: RO:0002211 GO:0008356 ! regulates asymmetric cell division [Term] id: GO:0009790 name: embryo development alt_id: GO:0009795 def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_plant synonym: "embryogenesis" EXACT [] synonym: "embryogenesis and morphogenesis" BROAD [] synonym: "embryonal development" EXACT [] xref: Reactome:R-HSA-5619507 "Activation of HOX genes during differentiation" xref: Wikipedia:Embryogenesis is_a: GO:0007275 ! multicellular organism development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000922 ! results in development of embryo relationship: RO:0002296 UBERON:0000922 ! results in development of embryo property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0009791 name: post-embryonic development def: "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." [GOC:go_curators] subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0007275 ! multicellular organism development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0009792 name: embryo development ending in birth or egg hatching def: "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] synonym: "embryogenesis" BROAD [] is_a: GO:0009790 ! embryo development relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0009798 name: axis specification def: "The establishment, maintenance and elaboration of a pattern along a line or around a point." [GOC:dph, GOC:go_curators, GOC:isa_complete] synonym: "axis determination" RELATED [] is_a: GO:0007389 ! pattern specification process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0009820 name: alkaloid metabolic process def: "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] subset: goslim_chembl synonym: "alkaloid metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:22315 ! has primary input or output alkaloid relationship: RO:0004007 CHEBI:22315 ! has primary input or output alkaloid [Term] id: GO:0009821 name: alkaloid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid anabolism" EXACT [] synonym: "alkaloid biosynthesis" EXACT [] synonym: "alkaloid formation" EXACT [] synonym: "alkaloid synthesis" EXACT [] is_a: GO:0009820 ! alkaloid metabolic process is_a: GO:0044550 ! secondary metabolite biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:22315 ! has primary output alkaloid relationship: RO:0004008 CHEBI:22315 ! has primary output alkaloid [Term] id: GO:0009822 name: alkaloid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid breakdown" EXACT [] synonym: "alkaloid catabolism" EXACT [] synonym: "alkaloid degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0009820 ! alkaloid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:22315 ! has primary input alkaloid relationship: RO:0004009 CHEBI:22315 ! has primary input alkaloid [Term] id: GO:0009880 name: embryonic pattern specification def: "The process that results in the patterns of cell differentiation that will arise in an embryo." [GOC:go_curators, ISBN:0521436125] synonym: "embryonic pattern biosynthesis" BROAD [] synonym: "embryonic pattern formation" BROAD [] synonym: "ventral/lateral system" RELATED [] is_a: GO:0007389 ! pattern specification process relationship: part_of GO:0009790 ! embryo development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0009887 name: animal organ morphogenesis def: "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544] synonym: "histogenesis and organogenesis" BROAD [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000062 ! results in morphogenesis of organ relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048513 ! animal organ development relationship: RO:0002298 UBERON:0000062 ! results in morphogenesis of organ [Term] id: GO:0009888 name: tissue development namespace: biological_process def: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208] synonym: "histogenesis" EXACT [] synonym: "histogenesis and organogenesis" BROAD [] xref: Wikipedia:Histogenesis is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000479 ! results in development of tissue relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002296 UBERON:0000479 ! results in development of tissue property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0009889 name: regulation of biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] subset: gocheck_do_not_annotate synonym: "regulation of anabolism" EXACT [] synonym: "regulation of biosynthesis" EXACT [] synonym: "regulation of formation" EXACT [] synonym: "regulation of synthesis" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009058 ! regulates biosynthetic process relationship: RO:0002211 GO:0009058 ! regulates biosynthetic process [Term] id: GO:0009890 name: negative regulation of biosynthetic process def: "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "down regulation of biosynthetic process" EXACT [] synonym: "down-regulation of biosynthetic process" EXACT [] synonym: "downregulation of biosynthetic process" EXACT [] synonym: "inhibition of biosynthetic process" NARROW [] synonym: "negative regulation of anabolism" EXACT [] synonym: "negative regulation of biosynthesis" EXACT [] synonym: "negative regulation of formation" EXACT [] synonym: "negative regulation of synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009058 ! negatively regulates biosynthetic process relationship: RO:0002212 GO:0009058 ! negatively regulates biosynthetic process [Term] id: GO:0009891 name: positive regulation of biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "activation of biosynthetic process" NARROW [] synonym: "positive regulation of anabolism" EXACT [] synonym: "positive regulation of biosynthesis" EXACT [] synonym: "positive regulation of formation" EXACT [] synonym: "positive regulation of synthesis" EXACT [] synonym: "stimulation of biosynthetic process" NARROW [] synonym: "up regulation of biosynthetic process" EXACT [] synonym: "up-regulation of biosynthetic process" EXACT [] synonym: "upregulation of biosynthetic process" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009058 ! positively regulates biosynthetic process relationship: RO:0002213 GO:0009058 ! positively regulates biosynthetic process [Term] id: GO:0009892 name: negative regulation of metabolic process alt_id: GO:0044252 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "down regulation of metabolic process" EXACT [] synonym: "down-regulation of metabolic process" EXACT [] synonym: "downregulation of metabolic process" EXACT [] synonym: "inhibition of metabolic process" NARROW [] synonym: "inhibition of organismal metabolic process" NARROW [] synonym: "negative regulation of metabolism" EXACT [] synonym: "negative regulation of multicellular organismal metabolic process" NARROW [] synonym: "negative regulation of organismal metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008152 ! negatively regulates metabolic process relationship: RO:0002212 GO:0008152 ! negatively regulates metabolic process [Term] id: GO:0009893 name: positive regulation of metabolic process alt_id: GO:0044253 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "activation of metabolic process" NARROW [] synonym: "positive regulation of metabolism" EXACT [] synonym: "positive regulation of multicellular organismal metabolic process" NARROW [] synonym: "positive regulation of organismal metabolism" NARROW [] synonym: "stimulation of metabolic process" NARROW [] synonym: "stimulation of organismal metabolic process" NARROW [] synonym: "up regulation of metabolic process" EXACT [] synonym: "up-regulation of metabolic process" EXACT [] synonym: "up-regulation of organismal metabolic process" NARROW [] synonym: "upregulation of metabolic process" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008152 ! positively regulates metabolic process relationship: RO:0002213 GO:0008152 ! positively regulates metabolic process [Term] id: GO:0009894 name: regulation of catabolic process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] subset: gocheck_do_not_annotate synonym: "regulation of breakdown" EXACT [] synonym: "regulation of catabolism" EXACT [] synonym: "regulation of degradation" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009056 ! regulates catabolic process relationship: RO:0002211 GO:0009056 ! regulates catabolic process [Term] id: GO:0009895 name: negative regulation of catabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "down regulation of catabolic process" EXACT [] synonym: "down-regulation of catabolic process" EXACT [] synonym: "downregulation of catabolic process" EXACT [] synonym: "inhibition of catabolic process" NARROW [] synonym: "negative regulation of breakdown" EXACT [] synonym: "negative regulation of catabolism" EXACT [] synonym: "negative regulation of degradation" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009056 ! negatively regulates catabolic process relationship: RO:0002212 GO:0009056 ! negatively regulates catabolic process [Term] id: GO:0009896 name: positive regulation of catabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "activation of catabolic process" NARROW [] synonym: "positive regulation of breakdown" EXACT [] synonym: "positive regulation of catabolism" EXACT [] synonym: "positive regulation of degradation" EXACT [] synonym: "stimulation of catabolic process" NARROW [] synonym: "up regulation of catabolic process" EXACT [] synonym: "up-regulation of catabolic process" EXACT [] synonym: "upregulation of catabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009056 ! positively regulates catabolic process relationship: RO:0002213 GO:0009056 ! positively regulates catabolic process [Term] id: GO:0009913 name: epidermal cell differentiation alt_id: GO:0043355 def: "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." [GOC:dph, GOC:go_curators, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb] synonym: "hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000362 ! results in acquisition of features of epidermal cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0008544 ! epidermis development relationship: RO:0002315 CL:0000362 ! results in acquisition of features of epidermal cell [Term] id: GO:0009914 name: hormone transport def: "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:tb] subset: goslim_pir is_a: GO:0006810 ! transport is_a: GO:0010817 ! regulation of hormone levels [Term] id: GO:0009948 name: anterior/posterior axis specification def: "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "anterior/posterior axis determination" RELATED [GOC:dph] is_a: GO:0009798 ! axis specification relationship: part_of GO:0009952 ! anterior/posterior pattern specification property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0009952 name: anterior/posterior pattern specification def: "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb] synonym: "anterior/posterior pattern formation" RELATED [] is_a: GO:0003002 ! regionalization property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0009966 name: regulation of signal transduction alt_id: GO:0035466 def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "regulation of signaling pathway" RELATED [] synonym: "regulation of signalling pathway" RELATED [GOC:mah] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007165 ! regulates signal transduction relationship: RO:0002211 GO:0007165 ! regulates signal transduction [Term] id: GO:0009967 name: positive regulation of signal transduction alt_id: GO:0035468 def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "activation of signal transduction" NARROW [] synonym: "positive regulation of signaling pathway" RELATED [] synonym: "positive regulation of signalling pathway" RELATED [GOC:mah] synonym: "stimulation of signal transduction" NARROW [] synonym: "up regulation of signal transduction" EXACT [] synonym: "up-regulation of signal transduction" EXACT [] synonym: "upregulation of signal transduction" EXACT [] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007165 ! positively regulates signal transduction relationship: RO:0002213 GO:0007165 ! positively regulates signal transduction [Term] id: GO:0009968 name: negative regulation of signal transduction alt_id: GO:0035467 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "down regulation of signal transduction" EXACT [] synonym: "down-regulation of signal transduction" EXACT [] synonym: "downregulation of signal transduction" EXACT [] synonym: "inhibition of signal transduction" NARROW [] synonym: "negative regulation of signaling pathway" RELATED [] synonym: "negative regulation of signalling pathway" RELATED [GOC:mah] xref: Reactome:R-HSA-8849472 "PTK6 Down-Regulation" is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007165 ! negatively regulates signal transduction relationship: RO:0002212 GO:0007165 ! negatively regulates signal transduction [Term] id: GO:0009987 name: cellular process alt_id: GO:0008151 alt_id: GO:0044763 alt_id: GO:0050875 def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate subset: goslim_plant synonym: "cell growth and/or maintenance" NARROW [] synonym: "cell physiology" EXACT [] synonym: "cellular physiological process" EXACT [] synonym: "single-organism cellular process" RELATED [] is_a: GO:0008150 ! biological process created_by: jl creation_date: 2012-12-11T16:56:55Z [Term] id: GO:0009992 name: intracellular water homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of water within a cell." [GOC:dph, GOC:tb] synonym: "cellular osmoregulation" RELATED [GOC:dph, GOC:tb] synonym: "cellular water homeostasis" EXACT [] is_a: GO:0006884 ! cell volume homeostasis is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: RO:0002332 CHEBI:15377 ! regulates levels of water relationship: RO:0002332 CHEBI:15377 ! regulates levels of water [Term] id: GO:0009994 name: oocyte differentiation def: "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." [GOC:go_curators, GOC:mtg_sensu] synonym: "oocyte cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000023 ! results in acquisition of features of oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048477 ! oogenesis relationship: RO:0002315 CL:0000023 ! results in acquisition of features of oocyte [Term] id: GO:0010001 name: glial cell differentiation alt_id: GO:0007404 alt_id: GO:0043360 def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." [GOC:go_curators, GOC:mtg_sensu] synonym: "glia cell differentiation" EXACT [] synonym: "neuroglia differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000125 ! results in acquisition of features of glial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042063 ! gliogenesis relationship: RO:0002315 CL:0000125 ! results in acquisition of features of glial cell [Term] id: GO:0010002 name: cardioblast differentiation def: "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] synonym: "cardiac precursor cell differentiation" EXACT [GOC:mtg_heart] synonym: "cardioblast cell differentiation" EXACT [] synonym: "cardiomyocyte generation" RELATED [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002664 ! results in acquisition of features of cardioblast relationship: RO:0002315 CL:0002664 ! results in acquisition of features of cardioblast [Term] id: GO:0010032 name: meiotic chromosome condensation def: "Compaction of chromatin structure prior to meiosis in eukaryotic cells." [PMID:10072401] synonym: "chromosome condensation involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0030261 ! chromosome condensation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0030261 ! chromosome condensation intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0010034 name: response to acetate def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:sm] is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0010038 name: response to metal ion def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:sm] synonym: "heavy metal sensitivity/resistance" RELATED [] synonym: "response to heavy metal" NARROW [] synonym: "response to metal" EXACT [] xref: Reactome:R-HSA-5660526 "Response to metal ions" is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation [Term] id: GO:0010070 name: zygote asymmetric cell division def: "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." [GOC:tb] synonym: "zygote asymmetric cytokinesis" RELATED [] is_a: GO:0008356 ! asymmetric cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000365 ! has primary input animal zygote relationship: RO:0004009 CL:0000365 ! has primary input animal zygote [Term] id: GO:0010160 name: formation of animal organ boundary alt_id: GO:0048862 def: "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." [GOC:dph, GOC:isa_complete, PMID:9611175] synonym: "organ boundary specification" EXACT [] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048859 ! formation of anatomical boundary intersection_of: BFO:0000066 UBERON:0000062 ! occurs in organ relationship: BFO:0000066 UBERON:0000062 ! occurs in organ relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048645 ! animal organ formation [Term] id: GO:0010171 name: body morphogenesis def: "The process in which the anatomical structures of the soma are generated and organized." [GOC:ems, ISBN:0140512888] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000468 ! results in morphogenesis of multicellular organism relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002298 UBERON:0000468 ! results in morphogenesis of multicellular organism [Term] id: GO:0010256 name: endomembrane system organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." [GOC:mah, GOC:sm] subset: goslim_drosophila synonym: "endomembrane organization" EXACT [] synonym: "endomembrane system organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0012505 ! results in organization of endomembrane system relationship: RO:0002592 GO:0012505 ! results in organization of endomembrane system [Term] id: GO:0010324 name: membrane invagination alt_id: GO:1902534 def: "The infolding of a membrane." [GOC:tb] subset: goslim_yeast synonym: "single-organism membrane invagination" RELATED [] is_a: GO:0061024 ! membrane organization created_by: jl creation_date: 2013-12-02T13:58:34Z [Term] id: GO:0010453 name: regulation of cell fate commitment def: "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045165 ! regulates cell fate commitment relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0045165 ! regulates cell fate commitment [Term] id: GO:0010454 name: negative regulation of cell fate commitment def: "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045165 ! negatively regulates cell fate commitment relationship: RO:0002212 GO:0045165 ! negatively regulates cell fate commitment [Term] id: GO:0010455 name: positive regulation of cell fate commitment def: "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045165 ! positively regulates cell fate commitment relationship: RO:0002213 GO:0045165 ! positively regulates cell fate commitment [Term] id: GO:0010463 name: mesenchymal cell proliferation def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0008019 ! acts on population of mesenchymal cell relationship: RO:0012003 CL:0008019 ! acts on population of mesenchymal cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0010464 name: regulation of mesenchymal cell proliferation def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010463 ! regulates mesenchymal cell proliferation relationship: RO:0002211 GO:0010463 ! regulates mesenchymal cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0010467 name: gene expression def: "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." [GOC:txnOH-2018, PMID:25934543, PMID:31580950] subset: goslim_flybase_ribbon xref: Wikipedia:Gene_expression is_a: GO:0009059 ! macromolecule biosynthetic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25419" xsd:anyURI [Term] id: GO:0010468 name: regulation of gene expression def: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] comment: This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation. subset: goslim_euk_cellular_processes_ribbon subset: goslim_plant_ribbon synonym: "gene regulation" RELATED [GOC:cjm] synonym: "regulation of gene product expression" RELATED [] synonym: "regulation of protein expression" NARROW [] xref: Reactome:R-HSA-163767 "PP2A-mediated dephosphorylation of key metabolic factors" xref: Reactome:R-HSA-9752946 "Expression and translocation of olfactory receptors" xref: Wikipedia:Regulation_of_gene_expression is_a: GO:0010556 ! regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010467 ! regulates gene expression relationship: RO:0002211 GO:0010467 ! regulates gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010470 name: regulation of gastrulation def: "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0045995 ! regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007369 ! regulates gastrulation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0007369 ! regulates gastrulation [Term] id: GO:0010481 name: epidermal cell division def: "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." [PMID:17450124] synonym: "hypodermal cell division" RELATED [GOC:kmv, GOC:rk] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000362 ! has primary input epidermal cell relationship: RO:0004009 CL:0000362 ! has primary input epidermal cell [Term] id: GO:0010482 name: regulation of epidermal cell division def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." [PMID:17450124] synonym: "regulation of hypodermal cell division" RELATED [GOC:kmv, GOC:rk] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010481 ! regulates epidermal cell division relationship: RO:0002211 GO:0010481 ! regulates epidermal cell division [Term] id: GO:0010496 name: intercellular transport alt_id: GO:1902585 def: "The movement of substances between cells." [GOC:dhl] synonym: "single organism intercellular transport" RELATED [GOC:TermGenie] synonym: "single-organism intercellular transport" RELATED [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 CL:0000000 ! has target start location cell intersection_of: RO:0002339 CL:0000000 ! has target end location cell intersection_of: RO:0002342 GO:0005615 ! results in transport across extracellular space relationship: RO:0002338 CL:0000000 ! has target start location cell relationship: RO:0002339 CL:0000000 ! has target end location cell relationship: RO:0002342 GO:0005615 ! results in transport across extracellular space created_by: jl creation_date: 2013-12-19T13:24:56Z [Term] id: GO:0010549 name: regulation of membrane disassembly def: "Any process that modulates the frequency, rate or extent of membrane disassembly." [GOC:dph, GOC:tb] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030397 ! regulates membrane disassembly relationship: RO:0002211 GO:0030397 ! regulates membrane disassembly [Term] id: GO:0010556 name: regulation of macromolecule biosynthetic process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009059 ! regulates macromolecule biosynthetic process relationship: RO:0002211 GO:0009059 ! regulates macromolecule biosynthetic process [Term] id: GO:0010557 name: positive regulation of macromolecule biosynthetic process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010604 ! positive regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009059 ! positively regulates macromolecule biosynthetic process relationship: RO:0002213 GO:0009059 ! positively regulates macromolecule biosynthetic process [Term] id: GO:0010558 name: negative regulation of macromolecule biosynthetic process def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] subset: gocheck_do_not_annotate is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010605 ! negative regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009059 ! negatively regulates macromolecule biosynthetic process relationship: RO:0002212 GO:0009059 ! negatively regulates macromolecule biosynthetic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30771" xsd:anyURI [Term] id: GO:0010559 name: regulation of glycoprotein biosynthetic process def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009101 ! regulates glycoprotein biosynthetic process relationship: RO:0002211 GO:0009101 ! regulates glycoprotein biosynthetic process [Term] id: GO:0010560 name: positive regulation of glycoprotein biosynthetic process def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009101 ! positively regulates glycoprotein biosynthetic process relationship: RO:0002213 GO:0009101 ! positively regulates glycoprotein biosynthetic process [Term] id: GO:0010561 name: negative regulation of glycoprotein biosynthetic process def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009101 ! negatively regulates glycoprotein biosynthetic process relationship: RO:0002212 GO:0009101 ! negatively regulates glycoprotein biosynthetic process [Term] id: GO:0010564 name: regulation of cell cycle process def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022402 ! regulates cell cycle process relationship: RO:0002211 GO:0022402 ! regulates cell cycle process [Term] id: GO:0010565 name: regulation of ketone metabolic process def: "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042180 ! regulates ketone metabolic process relationship: RO:0002211 GO:0042180 ! regulates ketone metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] id: GO:0010566 name: regulation of ketone biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0010565 ! regulation of ketone metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042181 ! regulates ketone biosynthetic process relationship: RO:0002211 GO:0042181 ! regulates ketone biosynthetic process [Term] id: GO:0010567 name: regulation of ketone catabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0010565 ! regulation of ketone metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042182 ! regulates ketone catabolic process relationship: RO:0002211 GO:0042182 ! regulates ketone catabolic process [Term] id: GO:0010594 name: regulation of endothelial cell migration def: "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043542 ! regulates endothelial cell migration relationship: RO:0002211 GO:0043542 ! regulates endothelial cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010595 name: positive regulation of endothelial cell migration def: "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043542 ! positively regulates endothelial cell migration relationship: RO:0002213 GO:0043542 ! positively regulates endothelial cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010596 name: negative regulation of endothelial cell migration def: "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043542 ! negatively regulates endothelial cell migration relationship: RO:0002212 GO:0043542 ! negatively regulates endothelial cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010604 name: positive regulation of macromolecule metabolic process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043170 ! positively regulates macromolecule metabolic process relationship: RO:0002213 GO:0043170 ! positively regulates macromolecule metabolic process [Term] id: GO:0010605 name: negative regulation of macromolecule metabolic process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043170 ! negatively regulates macromolecule metabolic process relationship: RO:0002212 GO:0043170 ! negatively regulates macromolecule metabolic process [Term] id: GO:0010608 name: post-transcriptional regulation of gene expression def: "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." [GOC:dph, GOC:tb] synonym: "posttranscriptional regulation of gene expression" EXACT [] is_a: GO:0010468 ! regulation of gene expression [Term] id: GO:0010611 name: regulation of cardiac muscle hypertrophy def: "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:dph, GOC:tb] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003300 ! regulates cardiac muscle hypertrophy relationship: RO:0002211 GO:0003300 ! regulates cardiac muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0010612 name: regulation of cardiac muscle adaptation def: "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:dph, GOC:tb] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014887 ! regulates cardiac muscle adaptation relationship: RO:0002211 GO:0014887 ! regulates cardiac muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0010613 name: positive regulation of cardiac muscle hypertrophy def: "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014742 ! positive regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003300 ! positively regulates cardiac muscle hypertrophy relationship: RO:0002213 GO:0003300 ! positively regulates cardiac muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0010614 name: negative regulation of cardiac muscle hypertrophy def: "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014741 ! negative regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003300 ! negatively regulates cardiac muscle hypertrophy relationship: RO:0002212 GO:0003300 ! negatively regulates cardiac muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0010615 name: positive regulation of cardiac muscle adaptation def: "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014744 ! positive regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014887 ! positively regulates cardiac muscle adaptation relationship: RO:0002213 GO:0014887 ! positively regulates cardiac muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0010616 name: negative regulation of cardiac muscle adaptation def: "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014745 ! negative regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014887 ! negatively regulates cardiac muscle adaptation relationship: RO:0002212 GO:0014887 ! negatively regulates cardiac muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0010623 name: programmed cell death involved in cell development def: "The activation of endogenous cellular processes that result in the death of a cell as part of its development." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] comment: This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure. synonym: "developmental programmed cell death" BROAD [] synonym: "programmed cell death involved in development" BROAD [] is_a: GO:0012501 ! programmed cell death is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0012501 ! programmed cell death intersection_of: part_of GO:0048468 ! cell development relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0048468 ! cell development [Term] id: GO:0010624 name: regulation of Schwann cell proliferation def: "Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014010 ! regulates Schwann cell proliferation relationship: RO:0002211 GO:0014010 ! regulates Schwann cell proliferation [Term] id: GO:0010625 name: positive regulation of Schwann cell proliferation def: "Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0010624 ! regulation of Schwann cell proliferation is_a: GO:0060252 ! positive regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014010 ! positively regulates Schwann cell proliferation relationship: RO:0002213 GO:0014010 ! positively regulates Schwann cell proliferation [Term] id: GO:0010626 name: negative regulation of Schwann cell proliferation def: "Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0010624 ! regulation of Schwann cell proliferation is_a: GO:0060253 ! negative regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014010 ! negatively regulates Schwann cell proliferation relationship: RO:0002212 GO:0014010 ! negatively regulates Schwann cell proliferation [Term] id: GO:0010628 name: positive regulation of gene expression def: "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010467 ! positively regulates gene expression relationship: RO:0002213 GO:0010467 ! positively regulates gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010629 name: negative regulation of gene expression def: "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] comment: This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation. synonym: "gene silencing" RELATED [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010467 ! negatively regulates gene expression relationship: RO:0002212 GO:0010467 ! negatively regulates gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010631 name: epithelial cell migration def: "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000066 ! results in movement of epithelial cell relationship: part_of GO:0090132 ! epithelium migration relationship: RO:0002565 CL:0000066 ! results in movement of epithelial cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0010632 name: regulation of epithelial cell migration def: "Any process that modulates the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0030334 ! regulation of cell migration is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010631 ! regulates epithelial cell migration relationship: RO:0002211 GO:0010631 ! regulates epithelial cell migration property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010633 name: negative regulation of epithelial cell migration def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010631 ! negatively regulates epithelial cell migration relationship: RO:0002212 GO:0010631 ! negatively regulates epithelial cell migration property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010634 name: positive regulation of epithelial cell migration def: "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010631 ! positively regulates epithelial cell migration relationship: RO:0002213 GO:0010631 ! positively regulates epithelial cell migration property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010638 name: positive regulation of organelle organization def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] subset: gocheck_do_not_annotate synonym: "positive regulation of organelle organisation" EXACT [GOC:mah] synonym: "positive regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006996 ! positively regulates organelle organization relationship: RO:0002213 GO:0006996 ! positively regulates organelle organization [Term] id: GO:0010639 name: negative regulation of organelle organization def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] subset: gocheck_do_not_annotate synonym: "negative regulation of organelle organisation" EXACT [GOC:mah] synonym: "negative regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006996 ! negatively regulates organelle organization relationship: RO:0002212 GO:0006996 ! negatively regulates organelle organization [Term] id: GO:0010646 name: regulation of cell communication def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007154 ! regulates cell communication relationship: RO:0002211 GO:0007154 ! regulates cell communication [Term] id: GO:0010647 name: positive regulation of cell communication def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007154 ! positively regulates cell communication relationship: RO:0002213 GO:0007154 ! positively regulates cell communication [Term] id: GO:0010648 name: negative regulation of cell communication def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007154 ! negatively regulates cell communication relationship: RO:0002212 GO:0007154 ! negatively regulates cell communication [Term] id: GO:0010656 name: negative regulation of muscle cell apoptotic process def: "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "negative regulation of muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010657 ! negatively regulates muscle cell apoptotic process relationship: RO:0002212 GO:0010657 ! negatively regulates muscle cell apoptotic process [Term] id: GO:0010657 name: muscle cell apoptotic process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." [CL:0000187, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "muscle cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000187 ! occurs in muscle cell relationship: BFO:0000066 CL:0000187 ! occurs in muscle cell relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0010658 name: striated muscle cell apoptotic process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "striated muscle cell apoptosis" NARROW [] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000737 ! occurs in striated muscle cell relationship: BFO:0000066 CL:0000737 ! occurs in striated muscle cell [Term] id: GO:0010659 name: cardiac muscle cell apoptotic process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [CL:0000746, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010658 ! striated muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell relationship: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell [Term] id: GO:0010660 name: regulation of muscle cell apoptotic process def: "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of muscle cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010657 ! regulates muscle cell apoptotic process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0010657 ! regulates muscle cell apoptotic process [Term] id: GO:0010661 name: positive regulation of muscle cell apoptotic process def: "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010657 ! positively regulates muscle cell apoptotic process relationship: RO:0002213 GO:0010657 ! positively regulates muscle cell apoptotic process [Term] id: GO:0010662 name: regulation of striated muscle cell apoptotic process def: "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010658 ! regulates striated muscle cell apoptotic process relationship: RO:0002211 GO:0010658 ! regulates striated muscle cell apoptotic process [Term] id: GO:0010663 name: positive regulation of striated muscle cell apoptotic process def: "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010658 ! positively regulates striated muscle cell apoptotic process relationship: RO:0002213 GO:0010658 ! positively regulates striated muscle cell apoptotic process [Term] id: GO:0010664 name: negative regulation of striated muscle cell apoptotic process def: "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of striated muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] synonym: "negative regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010658 ! negatively regulates striated muscle cell apoptotic process relationship: RO:0002212 GO:0010658 ! negatively regulates striated muscle cell apoptotic process [Term] id: GO:0010665 name: regulation of cardiac muscle cell apoptotic process def: "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010659 ! regulates cardiac muscle cell apoptotic process relationship: RO:0002211 GO:0010659 ! regulates cardiac muscle cell apoptotic process [Term] id: GO:0010666 name: positive regulation of cardiac muscle cell apoptotic process def: "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010663 ! positive regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010659 ! positively regulates cardiac muscle cell apoptotic process relationship: RO:0002213 GO:0010659 ! positively regulates cardiac muscle cell apoptotic process [Term] id: GO:0010667 name: negative regulation of cardiac muscle cell apoptotic process def: "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of cardiac muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] synonym: "negative regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010664 ! negative regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010659 ! negatively regulates cardiac muscle cell apoptotic process relationship: RO:0002212 GO:0010659 ! negatively regulates cardiac muscle cell apoptotic process [Term] id: GO:0010668 name: ectodermal cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000221 ! results in acquisition of features of ectodermal cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007398 ! ectoderm development relationship: RO:0002315 CL:0000221 ! results in acquisition of features of ectodermal cell [Term] id: GO:0010700 name: negative regulation of norepinephrine secretion def: "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033604 ! negative regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048243 ! negatively regulates norepinephrine secretion relationship: RO:0002212 GO:0048243 ! negatively regulates norepinephrine secretion [Term] id: GO:0010701 name: positive regulation of norepinephrine secretion def: "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033605 ! positive regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048243 ! positively regulates norepinephrine secretion relationship: RO:0002213 GO:0048243 ! positively regulates norepinephrine secretion [Term] id: GO:0010710 name: regulation of collagen catabolic process def: "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030574 ! regulates collagen catabolic process relationship: RO:0002211 GO:0030574 ! regulates collagen catabolic process [Term] id: GO:0010711 name: negative regulation of collagen catabolic process def: "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of collagen catabolic process" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010713 ! negative regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030574 ! negatively regulates collagen catabolic process relationship: RO:0002212 GO:0030574 ! negatively regulates collagen catabolic process [Term] id: GO:0010712 name: regulation of collagen metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032963 ! regulates collagen metabolic process relationship: RO:0002211 GO:0032963 ! regulates collagen metabolic process [Term] id: GO:0010713 name: negative regulation of collagen metabolic process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032963 ! negatively regulates collagen metabolic process relationship: RO:0002212 GO:0032963 ! negatively regulates collagen metabolic process [Term] id: GO:0010714 name: positive regulation of collagen metabolic process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "positive regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032963 ! positively regulates collagen metabolic process relationship: RO:0002213 GO:0032963 ! positively regulates collagen metabolic process [Term] id: GO:0010715 name: regulation of extracellular matrix disassembly def: "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022617 ! regulates extracellular matrix disassembly relationship: RO:0002211 GO:0022617 ! regulates extracellular matrix disassembly [Term] id: GO:0010716 name: negative regulation of extracellular matrix disassembly def: "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of extracellular matrix disassembly" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022617 ! negatively regulates extracellular matrix disassembly relationship: RO:0002212 GO:0022617 ! negatively regulates extracellular matrix disassembly [Term] id: GO:0010717 name: regulation of epithelial to mesenchymal transition def: "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001837 ! regulates epithelial to mesenchymal transition relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0001837 ! regulates epithelial to mesenchymal transition [Term] id: GO:0010718 name: positive regulation of epithelial to mesenchymal transition def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001837 ! positively regulates epithelial to mesenchymal transition relationship: RO:0002213 GO:0001837 ! positively regulates epithelial to mesenchymal transition [Term] id: GO:0010719 name: negative regulation of epithelial to mesenchymal transition def: "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001837 ! negatively regulates epithelial to mesenchymal transition relationship: RO:0002212 GO:0001837 ! negatively regulates epithelial to mesenchymal transition [Term] id: GO:0010720 name: positive regulation of cell development def: "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048468 ! positively regulates cell development relationship: RO:0002213 GO:0048468 ! positively regulates cell development [Term] id: GO:0010721 name: negative regulation of cell development def: "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048468 ! negatively regulates cell development relationship: RO:0002212 GO:0048468 ! negatively regulates cell development [Term] id: GO:0010761 name: fibroblast migration def: "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:BHF, GOC:dph, GOC:tb] synonym: "fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000057 ! results in movement of fibroblast relationship: RO:0002565 CL:0000057 ! results in movement of fibroblast property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0010762 name: regulation of fibroblast migration def: "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010761 ! regulates fibroblast migration relationship: RO:0002211 GO:0010761 ! regulates fibroblast migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010763 name: positive regulation of fibroblast migration def: "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010761 ! positively regulates fibroblast migration relationship: RO:0002213 GO:0010761 ! positively regulates fibroblast migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010764 name: negative regulation of fibroblast migration def: "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "negative regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010761 ! negatively regulates fibroblast migration relationship: RO:0002212 GO:0010761 ! negatively regulates fibroblast migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0010765 name: positive regulation of sodium ion transport def: "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006814 ! positively regulates sodium ion transport relationship: RO:0002213 GO:0006814 ! positively regulates sodium ion transport [Term] id: GO:0010766 name: negative regulation of sodium ion transport def: "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006814 ! negatively regulates sodium ion transport relationship: RO:0002212 GO:0006814 ! negatively regulates sodium ion transport [Term] id: GO:0010770 name: positive regulation of cell morphogenesis def: "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0022604 ! regulation of cell morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000902 ! positively regulates cell morphogenesis relationship: RO:0002213 GO:0000902 ! positively regulates cell morphogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24299" xsd:anyURI [Term] id: GO:0010771 name: negative regulation of cell morphogenesis def: "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0022604 ! regulation of cell morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000902 ! negatively regulates cell morphogenesis relationship: RO:0002212 GO:0000902 ! negatively regulates cell morphogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24299" xsd:anyURI [Term] id: GO:0010817 name: regulation of hormone levels def: "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0065008 ! regulation of biological quality [Term] id: GO:0010827 name: regulation of D-glucose transmembrane transport def: "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] synonym: "regulation of glucose transmembrane transport" EXACT [] synonym: "regulation of glucose transport" RELATED [] is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904659 ! regulates D-glucose transmembrane transport relationship: RO:0002211 GO:1904659 ! regulates D-glucose transmembrane transport [Term] id: GO:0010828 name: positive regulation of D-glucose transmembrane transport def: "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of glucose transmembrane transport" EXACT [] synonym: "positive regulation of glucose transport" RELATED [] is_a: GO:0010827 ! regulation of D-glucose transmembrane transport is_a: GO:0034764 ! positive regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904659 ! positively regulates D-glucose transmembrane transport relationship: RO:0002213 GO:1904659 ! positively regulates D-glucose transmembrane transport [Term] id: GO:0010829 name: negative regulation of D-glucose transmembrane transport def: "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] synonym: "negative regulation of glucose transmembrane transport" EXACT [] synonym: "negative regulation of glucose transport" RELATED [] is_a: GO:0010827 ! regulation of D-glucose transmembrane transport is_a: GO:0034763 ! negative regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904659 ! negatively regulates D-glucose transmembrane transport relationship: RO:0002212 GO:1904659 ! negatively regulates D-glucose transmembrane transport [Term] id: GO:0010830 name: regulation of myotube differentiation def: "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014902 ! regulates myotube differentiation relationship: RO:0002211 GO:0014902 ! regulates myotube differentiation [Term] id: GO:0010831 name: positive regulation of myotube differentiation def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014902 ! positively regulates myotube differentiation relationship: RO:0002213 GO:0014902 ! positively regulates myotube differentiation [Term] id: GO:0010832 name: negative regulation of myotube differentiation def: "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014902 ! negatively regulates myotube differentiation relationship: RO:0002212 GO:0014902 ! negatively regulates myotube differentiation [Term] id: GO:0010842 name: retina layer formation def: "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:1270266] synonym: "retinal lamination" EXACT [GOC:dph, GOC:tb] synonym: "retinal layer formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001781 ! results in formation of anatomical entity layer of retina relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003407 ! neural retina development relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye relationship: RO:0002297 UBERON:0001781 ! results in formation of anatomical entity layer of retina [Term] id: GO:0010876 name: lipid localization def: "Any process in which a lipid is transported to, or maintained in, a specific location." [GOC:BHF, GOC:dph, GOC:tb] synonym: "lipid localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0010893 name: positive regulation of steroid biosynthetic process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:tb] is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0046889 ! positive regulation of lipid biosynthetic process is_a: GO:0050810 ! regulation of steroid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006694 ! positively regulates steroid biosynthetic process relationship: RO:0002213 GO:0006694 ! positively regulates steroid biosynthetic process [Term] id: GO:0010894 name: negative regulation of steroid biosynthetic process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:BHF, GOC:tb] is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:0051055 ! negative regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006694 ! negatively regulates steroid biosynthetic process relationship: RO:0002212 GO:0006694 ! negatively regulates steroid biosynthetic process [Term] id: GO:0010906 name: regulation of glucose metabolic process def: "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006006 ! regulates glucose metabolic process relationship: RO:0002211 GO:0006006 ! regulates glucose metabolic process [Term] id: GO:0010907 name: positive regulation of glucose metabolic process def: "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "positive regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006006 ! positively regulates glucose metabolic process relationship: RO:0002213 GO:0006006 ! positively regulates glucose metabolic process [Term] id: GO:0010927 name: cellular component assembly involved in morphogenesis def: "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." [GOC:dph, GOC:tb] is_a: GO:0022607 ! cellular component assembly is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0022607 ! cellular component assembly intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0032989 ! cellular anatomical entity morphogenesis [Term] id: GO:0010937 name: regulation of cytoplasmic microtubule depolymerization def: "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." [GOC:dph, GOC:tb] is_a: GO:0031114 ! regulation of microtubule depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010938 ! regulates cytoplasmic microtubule depolymerization relationship: RO:0002211 GO:0010938 ! regulates cytoplasmic microtubule depolymerization [Term] id: GO:0010938 name: cytoplasmic microtubule depolymerization def: "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." [GOC:dph, GOC:tb] is_a: GO:0007019 ! microtubule depolymerization is_a: GO:0031122 ! cytoplasmic microtubule organization intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: BFO:0000066 GO:0005737 ! occurs in cytoplasm relationship: BFO:0000066 GO:0005737 ! occurs in cytoplasm [Term] id: GO:0010948 name: negative regulation of cell cycle process def: "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022402 ! negatively regulates cell cycle process relationship: RO:0002212 GO:0022402 ! negatively regulates cell cycle process created_by: tb creation_date: 2009-04-27T09:53:22Z [Term] id: GO:0010958 name: regulation of amino acid import across plasma membrane def: "Any process that modulates the frequency, rate or extent of amino acid import into a cell." [GOC:dph, GOC:tb] synonym: "regulation of amino acid import" BROAD [] is_a: GO:1903789 ! regulation of amino acid transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0089718 ! regulates amino acid import across plasma membrane relationship: RO:0002211 GO:0089718 ! regulates amino acid import across plasma membrane created_by: tb creation_date: 2009-05-06T11:33:12Z [Term] id: GO:0010959 name: regulation of metal ion transport def: "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030001 ! regulates metal ion transport relationship: RO:0002211 GO:0030001 ! regulates metal ion transport created_by: tb creation_date: 2009-05-06T11:40:55Z [Term] id: GO:0010962 name: regulation of glucan biosynthetic process def: "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:dph, GOC:tb] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009250 ! regulates glucan biosynthetic process relationship: RO:0002211 GO:0009250 ! regulates glucan biosynthetic process created_by: tb creation_date: 2009-05-11T12:17:53Z [Term] id: GO:0010968 name: regulation of microtubule nucleation def: "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0031113 ! regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007020 ! regulates microtubule nucleation relationship: RO:0002211 GO:0007020 ! regulates microtubule nucleation created_by: tb creation_date: 2009-05-20T11:51:21Z [Term] id: GO:0010970 name: transport along microtubule def: "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." [GOC:dph, GOC:mah, GOC:tb] synonym: "establishment of localization by movement along microtubule" EXACT [GOC:dph] synonym: "microtubule-based transport" BROAD [] synonym: "movement along microtubule" EXACT [] is_a: GO:0007018 ! microtubule-based movement is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule relationship: RO:0002341 GO:0005874 ! results in transport along microtubule created_by: tb creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0010975 name: regulation of neuron projection development def: "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "regulation of neurite development" NARROW [GOC:mah] synonym: "regulation of neurite formation" NARROW [GOC:mah] synonym: "regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031175 ! regulates neuron projection development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0031175 ! regulates neuron projection development created_by: tb creation_date: 2009-06-01T10:44:45Z [Term] id: GO:0010976 name: positive regulation of neuron projection development def: "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "positive regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "positive regulation of neurite development" NARROW [GOC:mah] synonym: "positive regulation of neurite formation" NARROW [GOC:mah] synonym: "positive regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031346 ! positive regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0031175 ! positively regulates neuron projection development relationship: RO:0002213 GO:0031175 ! positively regulates neuron projection development created_by: tb creation_date: 2009-06-01T10:46:44Z [Term] id: GO:0010977 name: negative regulation of neuron projection development def: "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "growth cone collapse" RELATED [GOC:pr] synonym: "negative regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "negative regulation of neurite development" NARROW [GOC:mah] synonym: "negative regulation of neurite formation" NARROW [GOC:mah] synonym: "negative regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031345 ! negative regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031175 ! negatively regulates neuron projection development relationship: RO:0002212 GO:0031175 ! negatively regulates neuron projection development created_by: tb creation_date: 2009-06-01T10:47:42Z [Term] id: GO:0012501 name: programmed cell death alt_id: GO:0016244 def: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] comment: Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] synonym: "nonapoptotic programmed cell death" NARROW [] synonym: "PCD" RELATED [] synonym: "RCD" RELATED [] synonym: "regulated cell death" BROAD [] xref: Reactome:R-HSA-5357801 "Programmed Cell Death" xref: Wikipedia:Programmed_cell_death is_a: GO:0008219 ! cell death intersection_of: GO:0008219 ! cell death intersection_of: starts_with GO:0007165 ! signal transduction relationship: starts_with GO:0007165 ! signal transduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24835" xsd:anyURI [Term] id: GO:0012505 name: endomembrane system def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] subset: goslim_candida subset: goslim_flybase_ribbon subset: goslim_yeast xref: Wikipedia:Endomembrane_system is_a: GO:0110165 ! cellular anatomical structure relationship: has_part GO:0005773 ! vacuole relationship: has_part GO:0005886 ! plasma membrane relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of CL:0000000 ! cell [Term] id: GO:0012506 name: vesicle membrane def: "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." [GOC:mah, GOC:vesicle] xref: NIF_Subcellular:sao1153182838 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0031982 ! vesicle relationship: part_of GO:0031982 ! vesicle [Term] id: GO:0014000 name: morula development def: "The process whose specific outcome is the progression of the morula over time. The morula is a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." [PMID:37935903, PMID:38386558, PMID:39361745] is_a: GO:0009790 ! embryo development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000085 ! results in development of morula relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002296 UBERON:0000085 ! results in development of morula property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29162" xsd:anyURI created_by: pg creation_date: 2024-11-12T09:13:07Z [Term] id: GO:0014003 name: oligodendrocyte development def: "The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system." [GOC:dgh, GOC:ef] synonym: "oligodendrocyte cell development" EXACT [] is_a: GO:0021782 ! glial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000128 ! results in development of oligodendrocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048709 ! oligodendrocyte differentiation relationship: RO:0002296 CL:0000128 ! results in development of oligodendrocyte [Term] id: GO:0014009 name: glial cell proliferation def: "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." [GOC:ef, ISBN:0878932585] synonym: "glia proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000125 ! acts on population of glial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042063 ! gliogenesis relationship: RO:0012003 CL:0000125 ! acts on population of glial cell [Term] id: GO:0014010 name: Schwann cell proliferation def: "The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:ef, ISBN:0878932585] is_a: GO:0014009 ! glial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000218 ! acts on population of myelinating Schwann cell relationship: RO:0012003 CL:0000218 ! acts on population of myelinating Schwann cell [Term] id: GO:0014013 name: regulation of gliogenesis def: "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] is_a: GO:0050767 ! regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042063 ! regulates gliogenesis relationship: RO:0002211 GO:0042063 ! regulates gliogenesis [Term] id: GO:0014014 name: negative regulation of gliogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "down regulation of gliogenesis" EXACT [] synonym: "down-regulation of gliogenesis" EXACT [] synonym: "downregulation of gliogenesis" EXACT [] synonym: "inhibition of gliogenesis" NARROW [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050768 ! negative regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042063 ! negatively regulates gliogenesis relationship: RO:0002212 GO:0042063 ! negatively regulates gliogenesis [Term] id: GO:0014015 name: positive regulation of gliogenesis def: "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "activation of gliogenesis" NARROW [] synonym: "stimulation of gliogenesis" NARROW [] synonym: "up regulation of gliogenesis" EXACT [] synonym: "up-regulation of gliogenesis" EXACT [] synonym: "upregulation of gliogenesis" EXACT [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050769 ! positive regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042063 ! positively regulates gliogenesis relationship: RO:0002213 GO:0042063 ! positively regulates gliogenesis [Term] id: GO:0014016 name: neuroblast differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." [GOC:ef, ISBN:0878932585] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000031 ! results in acquisition of features of neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048699 ! generation of neurons relationship: RO:0002315 CL:0000031 ! results in acquisition of features of neuroblast (sensu Vertebrata) [Term] id: GO:0014019 name: neuroblast development def: "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." [GOC:ef, ISBN:0878932585] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000031 ! results in development of neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014016 ! neuroblast differentiation relationship: RO:0002296 CL:0000031 ! results in development of neuroblast (sensu Vertebrata) [Term] id: GO:0014020 name: primary neural tube formation alt_id: GO:0014024 def: "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." [GOC:ef, ISBN:0878932585, PMID:15327780] synonym: "neural rod cavitation" RELATED [] synonym: "primary neural tube morphogenesis" EXACT [GOC:dph] synonym: "primary neurulation" EXACT [] is_a: GO:0001838 ! embryonic epithelial tube formation relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0001841 ! neural tube formation [Term] id: GO:0014023 name: neural rod formation def: "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005068 ! results in formation of anatomical entity neural rod relationship: in_taxon NCBITaxon:32443 ! Teleostei relationship: part_of GO:0014020 ! primary neural tube formation relationship: RO:0002297 UBERON:0005068 ! results in formation of anatomical entity neural rod [Term] id: GO:0014025 name: neural keel formation def: "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0007135 ! results in formation of anatomical entity neural keel relationship: in_taxon NCBITaxon:32443 ! Teleostei relationship: part_of GO:0014023 ! neural rod formation relationship: RO:0002297 UBERON:0007135 ! results in formation of anatomical entity neural keel [Term] id: GO:0014028 name: notochord formation def: "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002328 ! results in formation of anatomical entity notochord relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0007399 ! nervous system development relationship: part_of GO:0048570 ! notochord morphogenesis relationship: RO:0002297 UBERON:0002328 ! results in formation of anatomical entity notochord [Term] id: GO:0014029 name: neural crest formation def: "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:dh, GOC:ef] is_a: GO:0001837 ! epithelial to mesenchymal transition is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002342 ! results in formation of anatomical entity neural crest relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043009 ! chordate embryonic development relationship: RO:0002297 UBERON:0002342 ! results in formation of anatomical entity neural crest [Term] id: GO:0014031 name: mesenchymal cell development def: "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0008019 ! results in development of mesenchymal cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048762 ! mesenchymal cell differentiation relationship: RO:0002296 CL:0008019 ! results in development of mesenchymal cell [Term] id: GO:0014032 name: neural crest cell development def: "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048864 ! stem cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0011012 ! results in development of neural crest cell relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0014033 ! neural crest cell differentiation relationship: RO:0002296 CL:0011012 ! results in development of neural crest cell [Term] id: GO:0014033 name: neural crest cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." [GOC:dh, GOC:ef] is_a: GO:0048762 ! mesenchymal cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000333 ! results in acquisition of features of migratory neural crest cell relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002315 CL:0000333 ! results in acquisition of features of migratory neural crest cell [Term] id: GO:0014037 name: Schwann cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." [GOC:ef] is_a: GO:0010001 ! glial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000218 ! results in acquisition of features of myelinating Schwann cell relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0007422 ! peripheral nervous system development relationship: RO:0002315 CL:0000218 ! results in acquisition of features of myelinating Schwann cell [Term] id: GO:0014038 name: regulation of Schwann cell differentiation def: "Any process that modulates the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014037 ! regulates Schwann cell differentiation relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002211 GO:0014037 ! regulates Schwann cell differentiation [Term] id: GO:0014039 name: negative regulation of Schwann cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] synonym: "down regulation of Schwann cell differentiation" EXACT [] synonym: "down-regulation of Schwann cell differentiation" EXACT [] synonym: "downregulation of Schwann cell differentiation" EXACT [] synonym: "inhibition of Schwann cell differentiation" NARROW [] is_a: GO:0014038 ! regulation of Schwann cell differentiation is_a: GO:0045686 ! negative regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014037 ! negatively regulates Schwann cell differentiation relationship: RO:0002212 GO:0014037 ! negatively regulates Schwann cell differentiation [Term] id: GO:0014040 name: positive regulation of Schwann cell differentiation def: "Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] synonym: "activation of Schwann cell differentiation" NARROW [] synonym: "stimulation of Schwann cell differentiation" NARROW [] synonym: "up regulation of Schwann cell differentiation" EXACT [] synonym: "up-regulation of Schwann cell differentiation" EXACT [] synonym: "upregulation of Schwann cell differentiation" EXACT [] is_a: GO:0014038 ! regulation of Schwann cell differentiation is_a: GO:0045687 ! positive regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014037 ! positively regulates Schwann cell differentiation relationship: RO:0002213 GO:0014037 ! positively regulates Schwann cell differentiation [Term] id: GO:0014041 name: regulation of neuron maturation def: "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." [GOC:ef] is_a: GO:0045664 ! regulation of neuron differentiation is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042551 ! regulates neuron maturation relationship: RO:0002211 GO:0042551 ! regulates neuron maturation [Term] id: GO:0014042 name: positive regulation of neuron maturation def: "Any process that activates or increases the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "activation of neuron maturation" NARROW [] synonym: "stimulation of neuron maturation" NARROW [] synonym: "up regulation of neuron maturation" EXACT [] synonym: "up-regulation of neuron maturation" EXACT [] synonym: "upregulation of neuron maturation" EXACT [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903431 ! positive regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042551 ! positively regulates neuron maturation relationship: RO:0002213 GO:0042551 ! positively regulates neuron maturation [Term] id: GO:0014043 name: negative regulation of neuron maturation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "down regulation of neuron maturation" EXACT [] synonym: "down-regulation of neuron maturation" EXACT [] synonym: "downregulation of neuron maturation" EXACT [] synonym: "inhibition of neuron maturation" NARROW [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903430 ! negative regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042551 ! negatively regulates neuron maturation relationship: RO:0002212 GO:0042551 ! negatively regulates neuron maturation [Term] id: GO:0014044 name: Schwann cell development def: "The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." [GOC:dgh, GOC:ef] is_a: GO:0021782 ! glial cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000218 ! results in development of myelinating Schwann cell relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0014037 ! Schwann cell differentiation relationship: RO:0002296 CL:0000218 ! results in development of myelinating Schwann cell [Term] id: GO:0014055 name: acetylcholine secretion, neurotransmission def: "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." [GOC:ef] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0061526 ! acetylcholine secretion intersection_of: GO:0061526 ! acetylcholine secretion intersection_of: part_of GO:0007271 ! synaptic transmission, cholinergic relationship: part_of GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0014056 name: regulation of acetylcholine secretion, neurotransmission def: "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014055 ! regulates acetylcholine secretion, neurotransmission relationship: RO:0002211 GO:0014055 ! regulates acetylcholine secretion, neurotransmission [Term] id: GO:0014057 name: positive regulation of acetylcholine secretion, neurotransmission def: "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "activation of acetylcholine secretion" NARROW [] synonym: "stimulation of acetylcholine secretion" NARROW [] synonym: "up regulation of acetylcholine secretion" EXACT [] synonym: "up-regulation of acetylcholine secretion" EXACT [] synonym: "upregulation of acetylcholine secretion" EXACT [] is_a: GO:0001956 ! positive regulation of neurotransmitter secretion is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032224 ! positive regulation of synaptic transmission, cholinergic is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014055 ! positively regulates acetylcholine secretion, neurotransmission relationship: RO:0002213 GO:0014055 ! positively regulates acetylcholine secretion, neurotransmission [Term] id: GO:0014058 name: negative regulation of acetylcholine secretion, neurotransmission def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "down regulation of acetylcholine secretion" EXACT [] synonym: "down-regulation of acetylcholine secretion" EXACT [] synonym: "downregulation of acetylcholine secretion" EXACT [] synonym: "inhibition of acetylcholine secretion" NARROW [] is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032223 ! negative regulation of synaptic transmission, cholinergic is_a: GO:0046929 ! negative regulation of neurotransmitter secretion is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014055 ! negatively regulates acetylcholine secretion, neurotransmission relationship: RO:0002212 GO:0014055 ! negatively regulates acetylcholine secretion, neurotransmission [Term] id: GO:0014061 name: regulation of norepinephrine secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." [GOC:ef] synonym: "regulation of noradrenaline secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048243 ! regulates norepinephrine secretion relationship: RO:0002211 GO:0048243 ! regulates norepinephrine secretion [Term] id: GO:0014062 name: regulation of serotonin secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "regulation of serotonin release" RELATED [GOC:tb] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001820 ! regulates serotonin secretion relationship: RO:0002211 GO:0001820 ! regulates serotonin secretion [Term] id: GO:0014063 name: negative regulation of serotonin secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "down regulation of serotonin secretion" EXACT [] synonym: "down-regulation of serotonin secretion" EXACT [] synonym: "downregulation of serotonin secretion" EXACT [] synonym: "inhibition of serotonin secretion" NARROW [] synonym: "positive regulation of serotonin release" RELATED [GOC:tb] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043271 ! negative regulation of monoatomic ion transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001820 ! negatively regulates serotonin secretion relationship: RO:0002212 GO:0001820 ! negatively regulates serotonin secretion [Term] id: GO:0014064 name: positive regulation of serotonin secretion def: "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "activation of serotonin secretion" NARROW [] synonym: "positive regulation of serotonin release" RELATED [GOC:tb] synonym: "stimulation of serotonin secretion" NARROW [] synonym: "up regulation of serotonin secretion" EXACT [] synonym: "up-regulation of serotonin secretion" EXACT [] synonym: "upregulation of serotonin secretion" EXACT [] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043270 ! positive regulation of monoatomic ion transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001820 ! positively regulates serotonin secretion relationship: RO:0002213 GO:0001820 ! positively regulates serotonin secretion [Term] id: GO:0014075 name: response to amine def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:ef] synonym: "response to amine stimulus" EXACT [GOC:dos] is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0014706 name: striated muscle tissue development def: "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." [CL:0000737, GOC:dph, GOC:mtg_muscle] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002036 ! results in development of striated muscle tissue relationship: RO:0002296 UBERON:0002036 ! results in development of striated muscle tissue [Term] id: GO:0014733 name: regulation of skeletal muscle adaptation def: "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "regulation of skeletal muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043501 ! regulates skeletal muscle adaptation relationship: RO:0002211 GO:0043501 ! regulates skeletal muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014734 name: skeletal muscle hypertrophy def: "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014897 ! striated muscle hypertrophy is_a: GO:0043501 ! skeletal muscle adaptation intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014741 name: negative regulation of muscle hypertrophy def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014896 ! negatively regulates muscle hypertrophy relationship: RO:0002212 GO:0014896 ! negatively regulates muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014742 name: positive regulation of muscle hypertrophy def: "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014896 ! positively regulates muscle hypertrophy relationship: RO:0002213 GO:0014896 ! positively regulates muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014743 name: regulation of muscle hypertrophy def: "Any process that modulates the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014896 ! regulates muscle hypertrophy relationship: RO:0002211 GO:0014896 ! regulates muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014744 name: positive regulation of muscle adaptation def: "Any process that activates or increases the frequency, rate or extent of muscle adaptation." [GOC:mtg_muscle] synonym: "positive regulation of muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043500 ! positively regulates muscle adaptation relationship: RO:0002213 GO:0043500 ! positively regulates muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014745 name: negative regulation of muscle adaptation def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." [GOC:mtg_muscle] synonym: "negative regulation of muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043500 ! negatively regulates muscle adaptation relationship: RO:0002212 GO:0043500 ! negatively regulates muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014805 name: smooth muscle adaptation def: "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "smooth muscle plasticity" RELATED [] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue relationship: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014807 name: regulation of somitogenesis def: "Any process that modulates the frequency, rate or extent of somitogenesis." [GOC:mtg_muscle] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001756 ! regulates somitogenesis relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002211 GO:0001756 ! regulates somitogenesis [Term] id: GO:0014812 name: muscle cell migration def: "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000187, GOC:mtg_muscle] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000187 ! results in movement of muscle cell relationship: RO:0002565 CL:0000187 ! results in movement of muscle cell property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0014819 name: regulation of skeletal muscle contraction def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle] is_a: GO:0006942 ! regulation of striated muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003009 ! regulates skeletal muscle contraction relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0003009 ! regulates skeletal muscle contraction [Term] id: GO:0014821 name: phasic smooth muscle contraction def: "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations." [GOC:mtg_muscle] is_a: GO:0006939 ! smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014827 name: intestine smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine." [GOC:mtg_muscle, MA:0001539, MSH:D007422] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014831 name: gastro-intestinal system smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)." [GOC:mtg_muscle, MA:0001523, MSH:D041981] is_a: GO:0006939 ! smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014832 name: urinary bladder smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract." [GOC:mr, GOC:mtg_muscle, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0014848 ! urinary tract smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0014848 name: urinary tract smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." [GOC:ef, GOC:mtg_muscle, MA:0000325, MSH:D014551] is_a: GO:0006939 ! smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014849 name: ureter smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_muscle, MA:0000378] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014848 ! urinary tract smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014852 name: regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014819 ! regulation of skeletal muscle contraction [Term] id: GO:0014855 name: striated muscle cell proliferation def: "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:ef, GOC:mtg_muscle] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000737 ! acts on population of striated muscle cell relationship: RO:0012003 CL:0000737 ! acts on population of striated muscle cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0014856 name: skeletal muscle cell proliferation def: "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000188 ! acts on population of cell of skeletal muscle relationship: RO:0012003 CL:0000188 ! acts on population of cell of skeletal muscle property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0014857 name: regulation of skeletal muscle cell proliferation def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014856 ! regulates skeletal muscle cell proliferation relationship: RO:0002211 GO:0014856 ! regulates skeletal muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0014858 name: positive regulation of skeletal muscle cell proliferation def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014856 ! positively regulates skeletal muscle cell proliferation relationship: RO:0002213 GO:0014856 ! positively regulates skeletal muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0014859 name: negative regulation of skeletal muscle cell proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014856 ! negatively regulates skeletal muscle cell proliferation relationship: RO:0002212 GO:0014856 ! negatively regulates skeletal muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0014860 name: neurotransmitter secretion involved in regulation of skeletal muscle contraction def: "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." [GOC:dph, GOC:mtg_muscle, GOC:tb] synonym: "neurotransmitter secretion involved in control of skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: part_of GO:0014819 ! regulation of skeletal muscle contraction relationship: part_of GO:0014852 ! regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction [Term] id: GO:0014861 name: regulation of skeletal muscle contraction via regulation of action potential def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle] synonym: "regulation of skeletal muscle contraction via membrane action potential" RELATED [] is_a: GO:0014819 ! regulation of skeletal muscle contraction is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0100001 ! regulates regulation of skeletal muscle contraction by action potential relationship: RO:0002211 GO:0100001 ! regulates regulation of skeletal muscle contraction by action potential [Term] id: GO:0014866 name: skeletal myofibril assembly def: "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." [GOC:ef, GOC:mtg_muscle] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0098723 ! results in assembly of skeletal muscle myofibril relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002588 GO:0098723 ! results in assembly of skeletal muscle myofibril [Term] id: GO:0014872 name: myoblast division def: "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000056 ! has primary input myoblast relationship: RO:0004009 CL:0000056 ! has primary input myoblast [Term] id: GO:0014874 name: response to stimulus involved in regulation of muscle adaptation def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] synonym: "response to stimulus involved in regulation of muscle plasticity" RELATED [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation relationship: part_of GO:0043502 ! regulation of muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014878 name: response to electrical stimulus involved in regulation of muscle adaptation def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] synonym: "response to electrical stimulus involved in regulation of muscle plasticity" RELATED [] is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation is_a: GO:0051602 ! response to electrical stimulus intersection_of: GO:0051602 ! response to electrical stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014879 name: detection of electrical stimulus involved in regulation of muscle adaptation def: "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014878 ! response to electrical stimulus involved in regulation of muscle adaptation is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014887 name: cardiac muscle adaptation def: "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:mtg_muscle] synonym: "cardiac muscle plasticity" RELATED [] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue relationship: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014888 name: striated muscle adaptation def: "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "striated muscle plasticity" RELATED [] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0002036 ! occurs in striated muscle tissue relationship: BFO:0000066 UBERON:0002036 ! occurs in striated muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014895 name: smooth muscle hypertrophy def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." [GOC:mtg_muscle] is_a: GO:0014805 ! smooth muscle adaptation is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: BFO:0000066 UBERON:0001135 ! occurs in smooth muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014896 name: muscle hypertrophy def: "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." [GOC:mtg_muscle] xref: Wikipedia:Muscle_hypertrophy is_a: GO:0003012 ! muscle system process relationship: BFO:0000066 UBERON:0002385 ! occurs in muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014897 name: striated muscle hypertrophy def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: RO:0004009 UBERON:0002036 ! has primary input striated muscle tissue relationship: RO:0004009 UBERON:0002036 ! has primary input striated muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0014902 name: myotube differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002372 ! results in acquisition of features of myotube relationship: RO:0002315 CL:0002372 ! results in acquisition of features of myotube [Term] id: GO:0014904 name: myotube cell development def: "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0055002 ! striated muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0002372 ! results in development of myotube relationship: part_of GO:0014902 ! myotube differentiation relationship: RO:0002296 CL:0002372 ! results in development of myotube [Term] id: GO:0014909 name: smooth muscle cell migration def: "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000192 ! results in movement of smooth muscle cell relationship: RO:0002565 CL:0000192 ! results in movement of smooth muscle cell property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0014910 name: regulation of smooth muscle cell migration def: "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014909 ! regulates smooth muscle cell migration relationship: RO:0002211 GO:0014909 ! regulates smooth muscle cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0014911 name: positive regulation of smooth muscle cell migration def: "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014909 ! positively regulates smooth muscle cell migration relationship: RO:0002213 GO:0014909 ! positively regulates smooth muscle cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0014912 name: negative regulation of smooth muscle cell migration def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014909 ! negatively regulates smooth muscle cell migration relationship: RO:0002212 GO:0014909 ! negatively regulates smooth muscle cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0015031 name: protein transport alt_id: GO:0015831 def: "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_chembl subset: goslim_pir subset: goslim_yeast synonym: "enzyme transport" NARROW [] is_a: GO:0008104 ! intracellular protein localization is_a: GO:0042886 ! amide transport is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0015075 name: monoatomic ion transmembrane transporter activity def: "Enables the transfer of an ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "ion transmembrane transporter activity" BROAD [] synonym: "ion transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion relationship: part_of GO:0034220 {source="GO_REF:0000090"} ! monoatomic ion transmembrane transport relationship: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0015081 name: sodium ion transmembrane transporter activity alt_id: GO:0022816 def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF] synonym: "sodium transporter activity" EXACT [] is_a: GO:0046873 ! metal ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) relationship: part_of GO:0035725 ! sodium ion transmembrane transport relationship: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015106 name: bicarbonate transmembrane transporter activity def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] synonym: "hydrogencarbonate transmembrane transporter activity" EXACT [] xref: Reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate relationship: part_of GO:0015701 ! bicarbonate transport relationship: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26780" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015116 name: sulfate transmembrane transporter activity def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai] synonym: "sulfate permease activity" RELATED [] synonym: "sulphate transporter activity" EXACT [] xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol" xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol" xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol" xref: Reactome:R-HSA-9941470 "SLC26A11 imports SO4(2-) and H+ into cytosol" is_a: GO:1901682 ! sulfur compound transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:16189 ! has primary input sulfate relationship: part_of GO:1902358 {source="GO_REF:0000090"} ! sulfate transmembrane transport relationship: RO:0004009 CHEBI:16189 ! has primary input sulfate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015123 name: acetate transmembrane transporter activity def: "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai] is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: part_of GO:0035433 {source="GO_REF:0000090"} ! acetate transmembrane transport relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0015125 name: bile acid transmembrane transporter activity def: "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:ai] xref: Reactome:R-HSA-194079 "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194083 "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194130 "Transport (influx) of bile salts and acids by OATP-A" xref: Reactome:R-HSA-5661184 "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-5661198 "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-9733964 "SLC51A:SLC51B transports bile salts from cytosol to extracellular region" is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity is_a: GO:0170055 ! lipid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:3098 ! has primary input bile acid relationship: part_of GO:0015721 ! bile acid and bile salt transport relationship: RO:0004009 CHEBI:3098 ! has primary input bile acid [Term] id: GO:0015127 name: bilirubin transmembrane transporter activity def: "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684] xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-9661417 "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region" is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) relationship: part_of GO:0015723 ! bilirubin transport relationship: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0015144 name: carbohydrate transmembrane transporter activity alt_id: GO:1901476 def: "Enables the transfer of carbohydrate from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] synonym: "carbohydrate transporter activity" RELATED [] synonym: "sugar transporter" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: part_of GO:0034219 {source="GO_REF:0000090"} ! carbohydrate transmembrane transport relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0015145 name: monosaccharide transmembrane transporter activity def: "Enables the transfer of a monosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0051119 ! sugar transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: part_of GO:0015749 ! monosaccharide transmembrane transport relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide [Term] id: GO:0015149 name: hexose transmembrane transporter activity def: "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-189242 "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region" xref: Reactome:R-HSA-5638222 "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region" is_a: GO:0015145 ! monosaccharide transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: part_of GO:0008645 {source="GO_REF:0000090"} ! hexose transmembrane transport relationship: RO:0004009 CHEBI:18133 ! has primary input hexose [Term] id: GO:0015159 name: polysaccharide transmembrane transporter activity def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-9932121 "Unknown transporter exports CA to extracellular space" xref: Reactome:R-HSA-9932466 "Bcs complex exports pEtN-cellulose" is_a: GO:0015144 ! carbohydrate transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: part_of GO:0015774 ! polysaccharide transport relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0015171 name: amino acid transmembrane transporter activity alt_id: GO:0015359 def: "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "amino acid permease activity" EXACT [] synonym: "amino acid transporter activity" BROAD [] synonym: "amino acid/choline transmembrane transporter activity" NARROW [] synonym: "general amino acid permease activity" RELATED [] synonym: "hydroxy/aromatic amino acid permease activity" RELATED [] xref: Reactome:R-HSA-210439 "glutamate uptake by astrocytes" xref: Reactome:R-HSA-212642 "L-Glutamine transport into neurons" xref: Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine" xref: Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine" xref: Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol" xref: Reactome:R-HSA-352059 "SLC6A15-mediated amino acid uptake" xref: Reactome:R-HSA-352103 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352107 "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352108 "SLC38A2 (ATA2)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352119 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352136 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine" xref: Reactome:R-HSA-352158 "SLC16A10-mediated uptake of aromatic amino acids" xref: Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine" xref: Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine" xref: Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine" xref: Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine" xref: Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine" xref: Reactome:R-HSA-352371 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine" xref: Reactome:R-HSA-352379 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane" xref: Reactome:R-HSA-352385 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane" xref: Reactome:R-HSA-375405 "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-375417 "SLC36A1-mediated uptake of glycine, proline, and alanine" xref: Reactome:R-HSA-375473 "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375487 "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375768 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375770 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375776 "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375790 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-376200 "SLC7A10-mediated uptake of small neutral amino acids" xref: Reactome:R-HSA-378513 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate" xref: Reactome:R-HSA-379415 "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-379426 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine" xref: Reactome:R-HSA-379432 "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5653850 "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol" xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen" xref: Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion relationship: part_of GO:0003333 {source="GO_REF:0000090"} ! amino acid transmembrane transport relationship: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion [Term] id: GO:0015205 name: nucleobase transmembrane transporter activity alt_id: GO:0015392 def: "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:18282 ! has primary input nucleobase relationship: part_of GO:0015851 ! nucleobase transport relationship: RO:0004009 CHEBI:18282 ! has primary input nucleobase [Term] id: GO:0015629 name: actin cytoskeleton def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, ISBN:0395825172, ISBN:0815316194] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015630 name: microtubule cytoskeleton def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015669 name: gas transport def: "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport [Term] id: GO:0015671 name: oxygen transport def: "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] xref: Reactome:R-HSA-8981607 "Intracellular oxygen transport" is_a: GO:0015669 ! gas transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:15379 ! has primary input dioxygen relationship: RO:0004009 CHEBI:15379 ! has primary input dioxygen [Term] id: GO:0015695 name: organic cation transport def: "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." [GOC:ai] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:25697 ! has primary input organic cation relationship: RO:0004009 CHEBI:25697 ! has primary input organic cation [Term] id: GO:0015698 name: inorganic anion transport def: "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:krc] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:24834 ! has primary input inorganic anion relationship: RO:0004009 CHEBI:24834 ! has primary input inorganic anion [Term] id: GO:0015701 name: bicarbonate transport def: "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "hydrogencarbonate transport" EXACT [] xref: Reactome:R-HSA-1475029 "Reversible hydration of carbon dioxide" xref: Reactome:R-HSA-1480926 "O2/CO2 exchange in erythrocytes" xref: Reactome:R-HSA-425381 "Bicarbonate transporters" is_a: GO:0015711 ! organic anion transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate relationship: RO:0004009 CHEBI:17544 ! has primary input hydrogencarbonate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26780" xsd:anyURI [Term] id: GO:0015711 name: organic anion transport def: "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai, GOC:krc] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:25696 ! has primary input organic anion relationship: RO:0004009 CHEBI:25696 ! has primary input organic anion [Term] id: GO:0015718 name: monocarboxylic acid transport def: "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion relationship: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion [Term] id: GO:0015721 name: bile acid and bile salt transport def: "The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511] synonym: "bile acid transport" NARROW [] synonym: "bile salt transport" NARROW [] xref: Reactome:R-HSA-159418 "Recycling of bile acids and salts" is_a: GO:0006869 ! lipid transport is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:3098 ! has primary input bile acid relationship: RO:0004009 CHEBI:3098 ! has primary input bile acid [Term] id: GO:0015723 name: bilirubin transport def: "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0006835 ! dicarboxylic acid transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) relationship: RO:0004009 CHEBI:57977 ! has primary input bilirubin(2-) property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0015749 name: monosaccharide transmembrane transport alt_id: GO:1905950 def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GO_REF:0000069, GOC:TermGenie, GOC:vw] synonym: "monosaccharide transport" RELATED [] is_a: GO:0034219 ! carbohydrate transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide created_by: vw creation_date: 2017-02-19T10:41:27Z [Term] id: GO:0015774 name: polysaccharide transport def: "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai] is_a: GO:0008643 ! carbohydrate transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: part_of GO:0033037 ! polysaccharide localization relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0015833 name: peptide transport def: "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir is_a: GO:0042886 ! amide transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion relationship: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion [Term] id: GO:0015837 name: amine transport def: "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] subset: goslim_pir synonym: "amine/polyamine transport" RELATED [] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine relationship: RO:0004009 CHEBI:32952 ! has primary input amine [Term] id: GO:0015844 name: monoamine transport alt_id: GO:0015873 def: "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:63534 ! has primary input monoamine relationship: RO:0004009 CHEBI:63534 ! has primary input monoamine [Term] id: GO:0015849 name: organic acid transport def: "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] subset: goslim_pir is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:64709 ! has primary input organic acid relationship: RO:0004009 CHEBI:64709 ! has primary input organic acid [Term] id: GO:0015850 name: organic hydroxy compound transport def: "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." [GOC:ai] synonym: "organic alcohol transport" EXACT [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound relationship: RO:0004009 CHEBI:33822 ! has primary input organic hydroxy compound [Term] id: GO:0015851 name: nucleobase transport def: "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] synonym: "nucleobase transmembrane transport" EXACT [GOC:mah] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:18282 ! has primary input nucleobase relationship: RO:0004009 CHEBI:18282 ! has primary input nucleobase [Term] id: GO:0015870 name: acetylcholine transport def: "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] is_a: GO:0015695 ! organic cation transport is_a: GO:0071705 ! nitrogen compound transport is_a: GO:1901374 ! acetate ester transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine [Term] id: GO:0015874 name: norepinephrine transport def: "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai, ISBN:0198506732] synonym: "levarterenol transport" EXACT [] synonym: "noradrenaline transport" EXACT [] is_a: GO:0015695 ! organic cation transport is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) relationship: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0015931 name: nucleobase-containing compound transport def: "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir subset: goslim_yeast synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity relationship: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity [Term] id: GO:0015932 name: nucleobase-containing compound transmembrane transporter activity def: "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." [GOC:ai] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity" RELATED [GOC:dph, GOC:tb] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity relationship: part_of GO:0015931 ! nucleobase-containing compound transport relationship: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity [Term] id: GO:0015980 name: energy derivation by oxidation of organic compounds def: "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released." [GOC:mah] synonym: "chemoorganotrophy" EXACT [] is_a: GO:0006091 ! generation of precursor metabolites and energy [Term] id: GO:0016020 name: membrane alt_id: GO:0016021 alt_id: GO:0098589 alt_id: GO:0098805 def: "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "integral component of membrane" NARROW [] synonym: "integral to membrane" NARROW [] synonym: "membrane region" NARROW [] synonym: "region of membrane" NARROW [] synonym: "transmembrane" RELATED [GOC:mah] synonym: "whole membrane" NARROW [] xref: Wikipedia:Biological_membrane xref: Wikipedia:Transmembrane_protein is_a: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0031012 ! extracellular matrix creation_date: 2014-03-06T11:37:54Z [Term] id: GO:0016042 name: lipid catabolic process alt_id: GO:0006724 alt_id: GO:0044240 def: "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid breakdown" EXACT [] synonym: "lipid catabolism" EXACT [] synonym: "lipid degradation" EXACT [] synonym: "lipolysis" EXACT [] synonym: "multicellular organism lipid catabolic process" NARROW [] synonym: "multicellular organismal lipid catabolic process" NARROW [] xref: Wikipedia:Lipid_catabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0016043 name: cellular component organization alt_id: GO:0044235 alt_id: GO:0071842 def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:ai, GOC:jl, GOC:mah] subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon synonym: "cell organisation" EXACT [] synonym: "cell organization and biogenesis" RELATED [GOC:mah] synonym: "cellular component organisation at cellular level" EXACT [GOC:mah] synonym: "cellular component organisation in other organism" EXACT [GOC:mah] synonym: "cellular component organization at cellular level" EXACT [] synonym: "cellular component organization in other organism" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0005575 ! results in organization of cellular_component relationship: RO:0002592 GO:0005575 ! results in organization of cellular_component [Term] id: GO:0016049 name: cell growth alt_id: GO:0048591 def: "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:ai] subset: gocheck_do_not_annotate subset: goslim_drosophila subset: goslim_pir subset: goslim_plant synonym: "cell expansion" RELATED [] synonym: "cellular growth" EXACT [] synonym: "growth of cell" EXACT [] synonym: "metabolic process resulting in cell growth" RELATED [] synonym: "metabolism resulting in cell growth" RELATED [] synonym: "non-developmental cell growth" RELATED [GOC:mah] synonym: "non-developmental growth of a unicellular organism" RELATED [GOC:mah] is_a: GO:0009987 ! cellular process is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000000 ! results in growth of cell relationship: RO:0002343 CL:0000000 ! results in growth of cell [Term] id: GO:0016050 name: vesicle organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." [GOC:mah] subset: goslim_pir subset: goslim_yeast synonym: "vesicle organisation" EXACT [] synonym: "vesicle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031982 ! results in organization of vesicle relationship: RO:0002592 GO:0031982 ! results in organization of vesicle [Term] id: GO:0016051 name: carbohydrate biosynthetic process alt_id: GO:0006093 def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "anabolic carbohydrate metabolic process" EXACT [] synonym: "anabolic carbohydrate metabolism" EXACT [] synonym: "carbohydrate anabolism" EXACT [] synonym: "carbohydrate biosynthesis" EXACT [] synonym: "carbohydrate formation" EXACT [] synonym: "carbohydrate synthesis" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:16646 ! has primary output carbohydrate relationship: RO:0004008 CHEBI:16646 ! has primary output carbohydrate [Term] id: GO:0016052 name: carbohydrate catabolic process alt_id: GO:0006095 alt_id: GO:0044276 alt_id: GO:0044724 def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "carbohydrate breakdown" EXACT [] synonym: "carbohydrate catabolism" EXACT [] synonym: "carbohydrate degradation" EXACT [] synonym: "catabolic carbohydrate metabolic process" EXACT [] synonym: "catabolic carbohydrate metabolism" EXACT [] synonym: "multicellular organismal carbohydrate catabolic process" NARROW [] synonym: "single-organism carbohydrate catabolic process" RELATED [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate relationship: RO:0004009 CHEBI:16646 ! has primary input carbohydrate created_by: jl creation_date: 2012-10-23T16:34:39Z [Term] id: GO:0016053 name: organic acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid anabolism" EXACT [] synonym: "organic acid biosynthesis" EXACT [] synonym: "organic acid formation" EXACT [] synonym: "organic acid synthesis" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044283 ! small molecule biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:64709 ! has primary output organic acid relationship: RO:0004008 CHEBI:64709 ! has primary output organic acid [Term] id: GO:0016054 name: organic acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid breakdown" EXACT [] synonym: "organic acid catabolism" EXACT [] synonym: "organic acid degradation" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044282 ! small molecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:64709 ! has primary input organic acid relationship: RO:0004009 CHEBI:64709 ! has primary input organic acid [Term] id: GO:0016057 name: regulation of membrane potential in photoreceptor cell def: "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] synonym: "changes in polarization state of photoreceptor cell membrane" EXACT [GOC:dph, GOC:tb] is_a: GO:0042391 ! regulation of membrane potential intersection_of: GO:0042391 ! regulation of membrane potential intersection_of: BFO:0000066 CL:0000210 ! occurs in photoreceptor cell relationship: BFO:0000066 CL:0000210 ! occurs in photoreceptor cell [Term] id: GO:0016070 name: RNA metabolic process def: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_euk_cellular_processes_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_prokaryote synonym: "RNA metabolism" EXACT [] xref: Reactome:R-HSA-8953854 "Metabolism of RNA" is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33697 ! has primary input or output ribonucleic acid relationship: RO:0004007 CHEBI:33697 ! has primary input or output ribonucleic acid [Term] id: GO:0016078 name: tRNA decay def: "The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis." [GOC:ai] synonym: "tRNA breakdown" EXACT [] synonym: "tRNA catabolic process" EXACT [] synonym: "tRNA catabolism" EXACT [] synonym: "tRNA degradation" EXACT [] xref: Reactome:R-HSA-9708296 "tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis" is_a: GO:0006399 ! tRNA metabolic process is_a: GO:0006401 ! RNA catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 SO:0000253 ! has primary input relationship: RO:0004009 SO:0000253 ! has primary input property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27141" xsd:anyURI [Term] id: GO:0016192 name: vesicle-mediated transport alt_id: GO:0006899 def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_pir subset: goslim_pombe synonym: "nonselective vesicle transport" NARROW [] synonym: "protein sorting along secretory pathway" RELATED [] synonym: "vesicle trafficking" RELATED [] synonym: "vesicle transport" EXACT [] synonym: "vesicular transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002608 GO:0031982 ! process has causal agent vesicle relationship: RO:0002608 GO:0031982 ! process has causal agent vesicle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25421" xsd:anyURI [Term] id: GO:0016202 name: regulation of striated muscle tissue development def: "Any process that modulates the frequency, rate or extent of striated muscle development." [GOC:go_curators] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014706 ! regulates striated muscle tissue development relationship: RO:0002211 GO:0014706 ! regulates striated muscle tissue development [Term] id: GO:0016301 name: kinase activity def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. synonym: "phosphokinase activity" EXACT [] xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm" xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines" is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0016321 name: female meiosis chromosome segregation def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai] is_a: GO:0045132 ! meiotic chromosome segregation intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0007143 ! female meiotic nuclear division relationship: part_of GO:0007143 ! female meiotic nuclear division property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0016325 name: oocyte microtubule cytoskeleton organization alt_id: GO:0048130 def: "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11231123] synonym: "oocyte microtubule cytoskeleton organisation" EXACT [] is_a: GO:0030951 ! establishment or maintenance of microtubule cytoskeleton polarity intersection_of: GO:0016043 ! cellular component organization intersection_of: BFO:0000066 CL:0000023 ! occurs in oocyte intersection_of: RO:0002592 GO:0015630 ! results in organization of microtubule cytoskeleton relationship: BFO:0000066 CL:0000023 ! occurs in oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007308 ! oocyte construction [Term] id: GO:0016331 name: morphogenesis of embryonic epithelium def: "The process in which the anatomical structures of embryonic epithelia are generated and organized." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis [Term] id: GO:0016477 name: cell migration def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] xref: Wikipedia:Cell_migration is_a: GO:0048870 ! cell motility property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24787" xsd:anyURI property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0016482 name: cytosolic transport def: "The directed movement of substances or organelles within the cytosol." [GOC:ai] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005829 ! occurs in cytosol relationship: BFO:0000066 GO:0005829 ! occurs in cytosol property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26386" xsd:anyURI [Term] id: GO:0016525 name: negative regulation of angiogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." [GOC:go_curators] synonym: "down regulation of angiogenesis" EXACT [] synonym: "down-regulation of angiogenesis" EXACT [] synonym: "downregulation of angiogenesis" EXACT [] synonym: "inhibition of angiogenesis" NARROW [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001525 ! negatively regulates angiogenesis relationship: RO:0002212 GO:0001525 ! negatively regulates angiogenesis [Term] id: GO:0016528 name: sarcoplasm def: "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." [ISBN:0198547684] xref: Wikipedia:Sarcoplasm is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of CL:0000187 ! muscle cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000187 ! muscle cell [Term] id: GO:0016740 name: transferase activity def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [EC:2.-.-.-] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" xref: Reactome:R-HSA-5333607 "GSSeH combines with bGalNAc derivative to form GSSebGalNac" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0016746 name: acyltransferase activity alt_id: GO:0008415 def: "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)." [EC:2.3.-.-] subset: goslim_chembl subset: goslim_drosophila synonym: "transferase activity, transferring acyl groups" EXACT [] xref: EC:2.3.-.- xref: Reactome:R-HSA-159431 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine" xref: Reactome:R-HSA-192312 "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate" xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate" xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" is_a: GO:0016740 ! transferase activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20486" xsd:anyURI [Term] id: GO:0016755 name: aminoacyltransferase activity def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)." [GOC:jl] synonym: "transferase activity, transferring amino-acyl groups" EXACT [] xref: EC:2.3.2.- is_a: GO:0016746 ! acyltransferase activity [Term] id: GO:0016772 name: transferase activity, transferring phosphorus-containing groups is_a: GO:0016740 ! transferase activity property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0017085 name: response to insecticide def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." [GOC:curators] synonym: "insecticide resistance" RELATED [] synonym: "insecticide susceptibility/resistance" RELATED [] is_a: GO:0009636 ! response to toxic substance [Term] id: GO:0017126 name: nucleologenesis def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." [GOC:jl, ISBN:0198506732] synonym: "nucleolus assembly" NARROW [GOC:mah] synonym: "nucleolus biogenesis" EXACT [] is_a: GO:0007000 ! nucleolus organization is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: RO:0004008 GO:0005730 ! has primary output nucleolus relationship: RO:0004008 GO:0005730 ! has primary output nucleolus [Term] id: GO:0017145 name: stem cell division def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089] synonym: "stem cell renewal" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000034 ! has primary input stem cell relationship: RO:0004009 CL:0000034 ! has primary input stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0017148 name: negative regulation of translation alt_id: GO:0016478 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] synonym: "down regulation of protein biosynthetic process" EXACT [] synonym: "down-regulation of protein biosynthetic process" EXACT [] synonym: "downregulation of protein biosynthetic process" EXACT [] synonym: "inhibition of protein biosynthetic process" NARROW [] synonym: "negative regulation of protein anabolism" EXACT [] synonym: "negative regulation of protein biosynthesis" EXACT [] synonym: "negative regulation of protein biosynthetic process" EXACT [] synonym: "negative regulation of protein formation" EXACT [] synonym: "negative regulation of protein synthesis" EXACT [] synonym: "protein biosynthesis inhibitor activity" RELATED [] synonym: "protein biosynthetic process inhibitor activity" RELATED [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006412 ! negatively regulates translation relationship: RO:0002212 GO:0006412 ! negatively regulates translation [Term] id: GO:0017157 name: regulation of exocytosis def: "Any process that modulates the frequency, rate or extent of exocytosis." [GOC:go_curators] is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006887 ! regulates exocytosis relationship: RO:0002211 GO:0006887 ! regulates exocytosis [Term] id: GO:0018958 name: phenol-containing compound metabolic process def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] comment: Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds. synonym: "carbolic acid metabolic process" EXACT [] synonym: "carbolic acid metabolism" EXACT [] synonym: "hydroxybenzene metabolic process" EXACT [] synonym: "hydroxybenzene metabolism" EXACT [] synonym: "phenol-containing compound metabolism" EXACT [] xref: UM-BBD_pathwayID:phe is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33853 ! has primary input or output phenols relationship: RO:0004007 CHEBI:33853 ! has primary input or output phenols [Term] id: GO:0018989 name: apolysis namespace: biological_process def: "The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells." [GOC:jl] xref: Wikipedia:Apolysis is_a: GO:0022404 ! molting cycle process relationship: part_of GO:0007591 ! molting cycle, chitin-based cuticle [Term] id: GO:0019098 name: reproductive behavior alt_id: GO:0033057 alt_id: GO:0044704 alt_id: GO:0044705 def: "The specific behavior of an organism that is associated with reproduction." [GOC:jl, GOC:pr] synonym: "multi-organism reproductive behavior" NARROW [] synonym: "multicellular organism reproductive behavior" NARROW [] synonym: "reproductive behavior in a multicellular organism" EXACT [] synonym: "reproductive behaviour" EXACT [] synonym: "single-organism reproductive behavior" RELATED [] is_a: GO:0007610 ! behavior is_a: GO:0048609 ! multicellular organismal reproductive process intersection_of: GO:0007610 ! behavior intersection_of: GO:0048609 ! multicellular organismal reproductive process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23491" xsd:anyURI created_by: jl creation_date: 2012-09-19T16:01:37Z [Term] id: GO:0019216 name: regulation of lipid metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "regulation of lipid metabolism" EXACT [] xref: Reactome:R-HSA-2426168 "Activation of gene expression by SREBF (SREBP)" xref: Reactome:R-HSA-400206 "Regulation of lipid metabolism by PPARalpha" is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006629 ! regulates lipid metabolic process relationship: RO:0002211 GO:0006629 ! regulates lipid metabolic process [Term] id: GO:0019218 name: regulation of steroid metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "regulation of steroid metabolism" EXACT [] is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008202 ! regulates steroid metabolic process relationship: RO:0002211 GO:0008202 ! regulates steroid metabolic process [Term] id: GO:0019219 name: regulation of nucleobase-containing compound metabolic process def: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006139 ! regulates nucleobase-containing compound metabolic process relationship: RO:0002211 GO:0006139 ! regulates nucleobase-containing compound metabolic process [Term] id: GO:0019222 name: regulation of metabolic process alt_id: GO:0044246 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_metagenomics synonym: "regulation of metabolism" EXACT [] synonym: "regulation of multicellular organismal metabolic process" NARROW [] synonym: "regulation of organismal metabolic process" NARROW [GOC:tb] xref: Reactome:R-HSA-1989781 "PPARA activates gene expression" is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008152 ! regulates metabolic process relationship: RO:0002211 GO:0008152 ! regulates metabolic process [Term] id: GO:0019226 name: transmission of nerve impulse def: "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." [GOC:curators, ISBN:0815316194] synonym: "conduction of nerve impulse" EXACT [GOC:dph] synonym: "signal transmission along a neuron" EXACT [] is_a: GO:0050877 ! nervous system process relationship: has_part GO:0001508 ! action potential relationship: has_part GO:0007268 ! chemical synaptic transmission relationship: part_of GO:0007154 ! cell communication [Term] id: GO:0019228 name: neuronal action potential def: "An action potential that occurs in a neuron." [GOC:dph, GOC:isa_complete, GOC:tb] synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:0000540 ! occurs in neuron relationship: BFO:0000066 CL:0000540 ! occurs in neuron relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0019226 ! transmission of nerve impulse [Term] id: GO:0019233 name: sensory perception of pain def: "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. A painful stimulus is any physical or chemical event that has the potential to cause tissue damage (actual or perceived) and activates the nociceptive system." [GOC:curators] synonym: "nociception" RELATED [] synonym: "perception of physiological pain" NARROW [] xref: Wikipedia:Nociception is_a: GO:0007600 ! sensory perception property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29807" xsd:anyURI [Term] id: GO:0019318 name: hexose metabolic process def: "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose metabolism" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18133 ! has primary input or output hexose relationship: RO:0004007 CHEBI:18133 ! has primary input or output hexose [Term] id: GO:0019319 name: hexose biosynthetic process def: "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose anabolism" EXACT [] synonym: "hexose biosynthesis" EXACT [] synonym: "hexose formation" EXACT [] synonym: "hexose synthesis" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046364 ! monosaccharide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18133 ! has primary output hexose relationship: RO:0004008 CHEBI:18133 ! has primary output hexose [Term] id: GO:0019320 name: hexose catabolic process def: "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose breakdown" EXACT [] synonym: "hexose catabolism" EXACT [] synonym: "hexose degradation" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046365 ! monosaccharide catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose relationship: RO:0004009 CHEBI:18133 ! has primary input hexose [Term] id: GO:0019336 name: phenol-containing compound catabolic process def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] synonym: "phenol-containing compound breakdown" EXACT [] synonym: "phenol-containing compound catabolism" EXACT [] synonym: "phenol-containing compound degradation" EXACT [] xref: MetaCyc:PHENOLDEG-PWY is_a: GO:0009056 ! catabolic process is_a: GO:0018958 ! phenol-containing compound metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33853 ! has primary input phenols relationship: RO:0004009 CHEBI:33853 ! has primary input phenols [Term] id: GO:0019413 name: acetate biosynthetic process def: "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate anabolism" EXACT [] synonym: "acetate biosynthesis" EXACT [] synonym: "acetate formation" EXACT [] synonym: "acetate synthesis" EXACT [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:30089 ! has primary output acetate relationship: RO:0004008 CHEBI:30089 ! has primary output acetate [Term] id: GO:0019538 name: protein metabolic process alt_id: GO:0006411 alt_id: GO:0044267 alt_id: GO:0044268 def: "The chemical reactions and pathways involving a protein. Includes protein modification." [GOC:ma] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon synonym: "cellular protein metabolic process" EXACT [] synonym: "cellular protein metabolism" EXACT [] synonym: "multicellular organismal protein metabolic process" NARROW [] synonym: "protein metabolic process and modification" EXACT [] synonym: "protein metabolism" EXACT [] synonym: "protein metabolism and modification" EXACT [] xref: Reactome:R-HSA-392499 "Metabolism of proteins" xref: Wikipedia:Protein_metabolism is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:0043603 ! amide metabolic process is_a: GO:0044238 ! primary metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 PR:000000001 ! has primary input or output protein relationship: RO:0004007 PR:000000001 ! has primary input or output protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI [Term] id: GO:0019614 name: catechol-containing compound catabolic process def: "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] synonym: "catechol breakdown" RELATED [] synonym: "catechol catabolic process" RELATED [] synonym: "catechol catabolism" RELATED [] synonym: "catechol degradation" RELATED [] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0019336 ! phenol-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33566 ! has primary input catechols relationship: RO:0004009 CHEBI:33566 ! has primary input catechols [Term] id: GO:0019725 name: cellular homeostasis def: "Any process involved in the maintenance of an internal steady state at the level of the cell." [GOC:isa_complete, GOC:jl, ISBN:0395825172] subset: goslim_candida subset: goslim_euk_cellular_processes_ribbon subset: goslim_plant is_a: GO:0042592 ! homeostatic process intersection_of: GO:0042592 ! homeostatic process intersection_of: BFO:0000066 CL:0000000 ! occurs in cell disjoint_from: GO:0048872 ! homeostasis of number of cells relationship: BFO:0000066 CL:0000000 ! occurs in cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0019748 name: secondary metabolic process def: "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." [GOC:go_curators] subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_pombe synonym: "secondary metabolism" EXACT [] synonym: "secondary metabolite metabolic process" EXACT [] synonym: "secondary metabolite metabolism" EXACT [] xref: Wikipedia:Secondary_metabolism is_a: GO:0008152 ! metabolic process [Term] id: GO:0019752 name: carboxylic acid metabolic process def: "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "carboxylic acid metabolism" EXACT [] xref: Reactome:R-HSA-389661 "Glyoxylate metabolism and glycine degradation" is_a: GO:0043436 ! oxoacid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:29067 ! has primary input or output carboxylic acid anion relationship: RO:0004007 CHEBI:29067 ! has primary input or output carboxylic acid anion [Term] id: GO:0019755 name: one-carbon compound transport def: "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "one carbon compound transport" EXACT [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:64708 ! has primary input one-carbon compound relationship: RO:0004009 CHEBI:64708 ! has primary input one-carbon compound [Term] id: GO:0019827 name: stem cell population maintenance def: "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." [GOC:mah, ISBN:0878932437] synonym: "maintenance of pluripotency" RELATED [GOC:vk] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0098727 ! maintenance of cell number intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000034 ! acts on population of stem cell relationship: RO:0012003 CL:0000034 ! acts on population of stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0019867 name: outer membrane def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." [GOC:go_curators] subset: goslim_metagenomics is_a: GO:0016020 ! membrane [Term] id: GO:0019882 name: antigen processing and presentation alt_id: GO:0030333 def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] synonym: "antigen presentation" EXACT [] synonym: "antigen processing" EXACT [] xref: Wikipedia:Antigen_presentation is_a: GO:0002376 ! immune system process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0019953 name: sexual reproduction def: "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." [Wikipedia:Sexual_reproduction] comment: Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. subset: gocheck_do_not_annotate xref: Wikipedia:Sexual_reproduction is_a: GO:0022414 ! reproductive process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22929" xsd:anyURI [Term] id: GO:0021501 name: prechordal plate formation def: "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003063 ! results in formation of anatomical entity prechordal plate relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002297 UBERON:0003063 ! results in formation of anatomical entity prechordal plate [Term] id: GO:0021510 name: spinal cord development def: "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002240 ! results in development of spinal cord relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0007417 ! central nervous system development relationship: RO:0002296 UBERON:0002240 ! results in development of spinal cord [Term] id: GO:0021514 name: ventral spinal cord interneuron differentiation def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000066 UBERON:0002240 ! occurs in spinal cord intersection_of: RO:0002315 CL:0000099 ! results in acquisition of features of interneuron relationship: part_of GO:0021517 ! ventral spinal cord development relationship: RO:0002315 CL:0000099 ! results in acquisition of features of interneuron [Term] id: GO:0021515 name: cell differentiation in spinal cord def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000066 UBERON:0002240 ! occurs in spinal cord relationship: BFO:0000066 UBERON:0002240 ! occurs in spinal cord relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021510 ! spinal cord development [Term] id: GO:0021517 name: ventral spinal cord development def: "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002257 ! results in development of ventral horn of spinal cord relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021510 ! spinal cord development relationship: RO:0002296 UBERON:0002257 ! results in development of ventral horn of spinal cord [Term] id: GO:0021522 name: spinal cord motor neuron differentiation def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0011001 ! results in acquisition of features of spinal cord motor neuron relationship: part_of GO:0021517 ! ventral spinal cord development relationship: RO:0002315 CL:0011001 ! results in acquisition of features of spinal cord motor neuron [Term] id: GO:0021523 name: somatic motor neuron differentiation def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021522 ! spinal cord motor neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0005024 ! results in acquisition of features of somatomotor neuron relationship: RO:0002315 CL:0005024 ! results in acquisition of features of somatomotor neuron [Term] id: GO:0021532 name: neural tube patterning def: "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0003002 ! regionalization relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021915 ! neural tube development [Term] id: GO:0021533 name: cell differentiation in hindbrain def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021534 name: cell proliferation in hindbrain def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021535 name: cell migration in hindbrain def: "The orderly movement of a cell that will reside in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: BFO:0000066 UBERON:0002028 ! occurs in hindbrain relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021537 name: telencephalon development def: "The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] synonym: "cerebrum development" EXACT [GOC:sl, PMID:22331407] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001893 ! results in development of telencephalon relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0030900 ! forebrain development relationship: RO:0002296 UBERON:0001893 ! results in development of telencephalon [Term] id: GO:0021543 name: pallium development def: "The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000203 ! results in development of pallium relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021537 ! telencephalon development relationship: RO:0002296 UBERON:0000203 ! results in development of pallium [Term] id: GO:0021545 name: cranial nerve development def: "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021675 ! nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001785 ! results in development of cranial nerve relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002296 UBERON:0001785 ! results in development of cranial nerve [Term] id: GO:0021546 name: rhombomere development def: "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001892 ! results in development of rhombomere relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030902 ! hindbrain development relationship: RO:0002296 UBERON:0001892 ! results in development of rhombomere [Term] id: GO:0021547 name: midbrain-hindbrain boundary initiation def: "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:15541513] synonym: "isthmus biosynthesis" RELATED [GOC:cls] synonym: "isthmus formation" RELATED [GOC:cls] synonym: "MHB biosynthesis" EXACT [GOC:cls] synonym: "MHB formation" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary biosynthesis" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary formation" EXACT [GOC:cls] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003052 ! results in formation of anatomical entity midbrain-hindbrain boundary relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: RO:0002297 UBERON:0003052 ! results in formation of anatomical entity midbrain-hindbrain boundary [Term] id: GO:0021548 name: pons development def: "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000988 ! results in development of pons relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0022037 ! metencephalon development relationship: RO:0002296 UBERON:0000988 ! results in development of pons [Term] id: GO:0021550 name: medulla oblongata development def: "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla development" RELATED [GOC:cls] synonym: "myelencephalon development" RELATED [GOC:cls] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001896 ! results in development of medulla oblongata relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030902 ! hindbrain development relationship: RO:0002296 UBERON:0001896 ! results in development of medulla oblongata [Term] id: GO:0021551 name: central nervous system morphogenesis def: "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001017 ! results in morphogenesis of central nervous system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007417 ! central nervous system development relationship: RO:0002298 UBERON:0001017 ! results in morphogenesis of central nervous system [Term] id: GO:0021555 name: midbrain-hindbrain boundary morphogenesis def: "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] synonym: "isthmus morphogenesis" EXACT [GOC:cls] synonym: "MHB morphogenesis" EXACT [GOC:cls] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003052 ! results in morphogenesis of midbrain-hindbrain boundary relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: RO:0002298 UBERON:0003052 ! results in morphogenesis of midbrain-hindbrain boundary [Term] id: GO:0021556 name: central nervous system formation def: "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001017 ! results in formation of anatomical entity central nervous system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0021551 ! central nervous system morphogenesis relationship: RO:0002297 UBERON:0001017 ! results in formation of anatomical entity central nervous system [Term] id: GO:0021559 name: trigeminal nerve development def: "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V development" RELATED [GOC:cls] synonym: "cranial nerve 5 development" EXACT [GOC:cls] synonym: "cranial nerve V development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001645 ! results in development of trigeminal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0001645 ! results in development of trigeminal nerve [Term] id: GO:0021561 name: facial nerve development def: "The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII development" RELATED [GOC:cls] synonym: "cranial nerve 7 development" EXACT [GOC:cls] synonym: "cranial nerve VII development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001647 ! results in development of facial nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021783 ! preganglionic parasympathetic fiber development relationship: RO:0002296 UBERON:0001647 ! results in development of facial nerve [Term] id: GO:0021563 name: glossopharyngeal nerve development def: "Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX development" RELATED [GOC:cls] synonym: "cranial nerve 9 development" EXACT [GOC:cls] synonym: "cranial nerve IX development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001649 ! results in development of glossopharyngeal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0001649 ! results in development of glossopharyngeal nerve [Term] id: GO:0021564 name: vagus nerve development def: "The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X development" RELATED [GOC:cls] synonym: "cranial nerve 10 development" RELATED [GOC:cls] synonym: "cranial nerve X development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001759 ! results in development of vagus nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021783 ! preganglionic parasympathetic fiber development relationship: RO:0002296 UBERON:0001759 ! results in development of vagus nerve [Term] id: GO:0021565 name: accessory nerve development def: "The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI development" RELATED [GOC:cls] synonym: "cranial nerve 11 development" RELATED [GOC:cls] synonym: "cranial nerve XI development" EXACT [GOC:cls] synonym: "spinal accessory nerve development" EXACT [PMID:11533729] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002019 ! results in development of accessory XI nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: RO:0002296 UBERON:0002019 ! results in development of accessory XI nerve [Term] id: GO:0021566 name: hypoglossal nerve development def: "The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII development" RELATED [GOC:cls] synonym: "cranial nerve 12 development" RELATED [GOC:cls] synonym: "cranial nerve XII development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001650 ! results in development of hypoglossal nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: RO:0002296 UBERON:0001650 ! results in development of hypoglossal nerve [Term] id: GO:0021575 name: hindbrain morphogenesis def: "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "rhombencephalon morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002028 ! results in morphogenesis of hindbrain relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030902 ! hindbrain development relationship: RO:0002298 UBERON:0002028 ! results in morphogenesis of hindbrain [Term] id: GO:0021576 name: hindbrain formation def: "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002028 ! results in formation of anatomical entity hindbrain relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: RO:0002297 UBERON:0002028 ! results in formation of anatomical entity hindbrain [Term] id: GO:0021578 name: hindbrain maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0002028 ! results in maturation of hindbrain relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021626 ! central nervous system maturation relationship: part_of GO:0030902 ! hindbrain development relationship: RO:0002299 UBERON:0002028 ! results in maturation of hindbrain [Term] id: GO:0021579 name: medulla oblongata morphogenesis def: "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla morphogenesis" RELATED [] synonym: "myelencephalon morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001896 ! results in morphogenesis of medulla oblongata relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021550 ! medulla oblongata development relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: RO:0002298 UBERON:0001896 ! results in morphogenesis of medulla oblongata [Term] id: GO:0021580 name: medulla oblongata formation def: "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla biosynthesis" RELATED [] synonym: "medulla formation" RELATED [] synonym: "myelencephalon biosynthesis" RELATED [] synonym: "myelencephalon formation" RELATED [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001896 ! results in formation of anatomical entity medulla oblongata relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021576 ! hindbrain formation relationship: part_of GO:0021579 ! medulla oblongata morphogenesis relationship: RO:0002297 UBERON:0001896 ! results in formation of anatomical entity medulla oblongata [Term] id: GO:0021582 name: medulla oblongata maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla maturation" RELATED [] synonym: "myelencephalon maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001896 ! results in maturation of medulla oblongata relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021550 ! medulla oblongata development relationship: part_of GO:0021578 ! hindbrain maturation relationship: RO:0002299 UBERON:0001896 ! results in maturation of medulla oblongata [Term] id: GO:0021583 name: pons morphogenesis def: "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000988 ! results in morphogenesis of pons relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021548 ! pons development relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: RO:0002298 UBERON:0000988 ! results in morphogenesis of pons [Term] id: GO:0021584 name: pons formation def: "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000988 ! results in formation of anatomical entity pons relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021576 ! hindbrain formation relationship: part_of GO:0021583 ! pons morphogenesis relationship: RO:0002297 UBERON:0000988 ! results in formation of anatomical entity pons [Term] id: GO:0021586 name: pons maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0000988 ! results in maturation of pons relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021548 ! pons development relationship: part_of GO:0021578 ! hindbrain maturation relationship: RO:0002299 UBERON:0000988 ! results in maturation of pons [Term] id: GO:0021593 name: rhombomere morphogenesis def: "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001892 ! results in morphogenesis of rhombomere relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021546 ! rhombomere development relationship: RO:0002298 UBERON:0001892 ! results in morphogenesis of rhombomere [Term] id: GO:0021594 name: rhombomere formation def: "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001892 ! results in formation of anatomical entity rhombomere relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021593 ! rhombomere morphogenesis relationship: RO:0002297 UBERON:0001892 ! results in formation of anatomical entity rhombomere [Term] id: GO:0021602 name: cranial nerve morphogenesis def: "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001785 ! results in morphogenesis of cranial nerve relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021545 ! cranial nerve development relationship: RO:0002298 UBERON:0001785 ! results in morphogenesis of cranial nerve [Term] id: GO:0021603 name: cranial nerve formation def: "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001785 ! results in formation of anatomical entity cranial nerve relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021602 ! cranial nerve morphogenesis relationship: RO:0002297 UBERON:0001785 ! results in formation of anatomical entity cranial nerve [Term] id: GO:0021605 name: cranial nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021682 ! nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001785 ! results in maturation of cranial nerve relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021545 ! cranial nerve development relationship: RO:0002299 UBERON:0001785 ! results in maturation of cranial nerve [Term] id: GO:0021606 name: accessory nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI maturation" RELATED [] synonym: "spinal accessory nerve maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0002019 ! results in maturation of accessory XI nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0021565 ! accessory nerve development relationship: RO:0002299 UBERON:0002019 ! results in maturation of accessory XI nerve [Term] id: GO:0021607 name: accessory nerve morphogenesis def: "The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002019 ! results in morphogenesis of accessory XI nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0021565 ! accessory nerve development relationship: RO:0002298 UBERON:0002019 ! results in morphogenesis of accessory XI nerve [Term] id: GO:0021608 name: accessory nerve formation def: "The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI biosynthesis" RELATED [] synonym: "CN XI formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002019 ! results in formation of anatomical entity accessory XI nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0021607 ! accessory nerve morphogenesis relationship: RO:0002297 UBERON:0002019 ! results in formation of anatomical entity accessory XI nerve [Term] id: GO:0021610 name: facial nerve morphogenesis def: "The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001647 ! results in morphogenesis of facial nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021561 ! facial nerve development relationship: RO:0002298 UBERON:0001647 ! results in morphogenesis of facial nerve [Term] id: GO:0021611 name: facial nerve formation def: "The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII biosynthesis" RELATED [] synonym: "CN VII formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001647 ! results in formation of anatomical entity facial nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021610 ! facial nerve morphogenesis relationship: RO:0002297 UBERON:0001647 ! results in formation of anatomical entity facial nerve [Term] id: GO:0021613 name: facial nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001647 ! results in maturation of facial nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021561 ! facial nerve development relationship: RO:0002299 UBERON:0001647 ! results in maturation of facial nerve [Term] id: GO:0021614 name: glossopharyngeal nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001649 ! results in maturation of glossopharyngeal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021563 ! glossopharyngeal nerve development relationship: RO:0002299 UBERON:0001649 ! results in maturation of glossopharyngeal nerve [Term] id: GO:0021615 name: glossopharyngeal nerve morphogenesis def: "The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001649 ! results in morphogenesis of glossopharyngeal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021563 ! glossopharyngeal nerve development relationship: RO:0002298 UBERON:0001649 ! results in morphogenesis of glossopharyngeal nerve [Term] id: GO:0021616 name: glossopharyngeal nerve formation def: "The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX biosynthesis" RELATED [] synonym: "CN IX formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001649 ! results in formation of anatomical entity glossopharyngeal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021615 ! glossopharyngeal nerve morphogenesis relationship: RO:0002297 UBERON:0001649 ! results in formation of anatomical entity glossopharyngeal nerve [Term] id: GO:0021618 name: hypoglossal nerve morphogenesis def: "The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001650 ! results in morphogenesis of hypoglossal nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0021566 ! hypoglossal nerve development relationship: RO:0002298 UBERON:0001650 ! results in morphogenesis of hypoglossal nerve [Term] id: GO:0021619 name: hypoglossal nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001650 ! results in maturation of hypoglossal nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0021566 ! hypoglossal nerve development relationship: RO:0002299 UBERON:0001650 ! results in maturation of hypoglossal nerve [Term] id: GO:0021620 name: hypoglossal nerve formation def: "The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII biosynthesis" RELATED [] synonym: "CN XII formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001650 ! results in formation of anatomical entity hypoglossal nerve relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0021618 ! hypoglossal nerve morphogenesis relationship: RO:0002297 UBERON:0001650 ! results in formation of anatomical entity hypoglossal nerve [Term] id: GO:0021626 name: central nervous system maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007417 ! central nervous system development relationship: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system [Term] id: GO:0021635 name: trigeminal nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001645 ! results in maturation of trigeminal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021559 ! trigeminal nerve development relationship: RO:0002299 UBERON:0001645 ! results in maturation of trigeminal nerve [Term] id: GO:0021636 name: trigeminal nerve morphogenesis def: "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001645 ! results in morphogenesis of trigeminal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021559 ! trigeminal nerve development relationship: RO:0002298 UBERON:0001645 ! results in morphogenesis of trigeminal nerve [Term] id: GO:0021638 name: trigeminal nerve formation def: "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V biosynthesis" RELATED [] synonym: "CN V formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001645 ! results in formation of anatomical entity trigeminal nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis relationship: RO:0002297 UBERON:0001645 ! results in formation of anatomical entity trigeminal nerve [Term] id: GO:0021643 name: vagus nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001759 ! results in maturation of vagus nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021564 ! vagus nerve development relationship: RO:0002299 UBERON:0001759 ! results in maturation of vagus nerve [Term] id: GO:0021644 name: vagus nerve morphogenesis def: "The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001759 ! results in morphogenesis of vagus nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021564 ! vagus nerve development relationship: RO:0002298 UBERON:0001759 ! results in morphogenesis of vagus nerve [Term] id: GO:0021646 name: vagus nerve formation def: "The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X biosynthesis" RELATED [] synonym: "CN X formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001759 ! results in formation of anatomical entity vagus nerve relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021644 ! vagus nerve morphogenesis relationship: RO:0002297 UBERON:0001759 ! results in formation of anatomical entity vagus nerve [Term] id: GO:0021654 name: rhombomere boundary formation def: "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0018239 ! results in formation of anatomical entity rhombomere boundary relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021594 ! rhombomere formation relationship: RO:0002297 UBERON:0018239 ! results in formation of anatomical entity rhombomere boundary [Term] id: GO:0021675 name: nerve development def: "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001021 ! results in development of nerve relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002296 UBERON:0001021 ! results in development of nerve [Term] id: GO:0021682 name: nerve maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001021 ! results in maturation of nerve relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0021675 ! nerve development relationship: RO:0002299 UBERON:0001021 ! results in maturation of nerve [Term] id: GO:0021700 name: developmental maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] subset: goslim_chembl is_a: GO:0032502 ! developmental process [Term] id: GO:0021703 name: locus ceruleus development def: "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "locus caeruleus development" EXACT [] synonym: "locus coeruleus development" EXACT [] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002148 ! results in development of locus ceruleus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021548 ! pons development relationship: RO:0002296 UBERON:0002148 ! results in development of locus ceruleus [Term] id: GO:0021704 name: locus ceruleus morphogenesis def: "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002148 ! results in morphogenesis of locus ceruleus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021583 ! pons morphogenesis relationship: part_of GO:0021703 ! locus ceruleus development relationship: RO:0002298 UBERON:0002148 ! results in morphogenesis of locus ceruleus [Term] id: GO:0021705 name: locus ceruleus formation def: "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002148 ! results in formation of anatomical entity locus ceruleus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021584 ! pons formation relationship: part_of GO:0021704 ! locus ceruleus morphogenesis relationship: RO:0002297 UBERON:0002148 ! results in formation of anatomical entity locus ceruleus [Term] id: GO:0021706 name: locus ceruleus maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0002148 ! results in maturation of locus ceruleus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021586 ! pons maturation relationship: part_of GO:0021703 ! locus ceruleus development relationship: RO:0002299 UBERON:0002148 ! results in maturation of locus ceruleus [Term] id: GO:0021718 name: superior olivary nucleus development def: "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive development" RELATED [] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007247 ! results in development of nucleus of superior olivary complex relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021548 ! pons development relationship: RO:0002296 UBERON:0007247 ! results in development of nucleus of superior olivary complex [Term] id: GO:0021719 name: superior olivary nucleus morphogenesis def: "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007247 ! results in morphogenesis of nucleus of superior olivary complex relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021583 ! pons morphogenesis relationship: part_of GO:0021718 ! superior olivary nucleus development relationship: RO:0002298 UBERON:0007247 ! results in morphogenesis of nucleus of superior olivary complex [Term] id: GO:0021720 name: superior olivary nucleus formation def: "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0007247 ! results in formation of anatomical entity nucleus of superior olivary complex relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021584 ! pons formation relationship: part_of GO:0021719 ! superior olivary nucleus morphogenesis relationship: RO:0002297 UBERON:0007247 ! results in formation of anatomical entity nucleus of superior olivary complex [Term] id: GO:0021722 name: superior olivary nucleus maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0007247 ! results in maturation of nucleus of superior olivary complex relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021586 ! pons maturation relationship: part_of GO:0021718 ! superior olivary nucleus development relationship: RO:0002299 UBERON:0007247 ! results in maturation of nucleus of superior olivary complex [Term] id: GO:0021732 name: midbrain-hindbrain boundary maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] synonym: "isthmus maturation" RELATED [] synonym: "MHB maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0003052 ! results in maturation of midbrain-hindbrain boundary relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: RO:0002299 UBERON:0003052 ! results in maturation of midbrain-hindbrain boundary [Term] id: GO:0021743 name: hypoglossal nucleus development def: "The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002871 ! results in development of hypoglossal nucleus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021550 ! medulla oblongata development relationship: RO:0002296 UBERON:0002871 ! results in development of hypoglossal nucleus [Term] id: GO:0021751 name: salivary nucleus development def: "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004133 ! results in development of salivatory nucleus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021548 ! pons development relationship: RO:0002296 UBERON:0004133 ! results in development of salivatory nucleus [Term] id: GO:0021753 name: superior salivary nucleus development def: "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021751 ! salivary nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002149 ! results in development of superior salivatory nucleus relationship: RO:0002296 UBERON:0002149 ! results in development of superior salivatory nucleus [Term] id: GO:0021754 name: facial nucleus development def: "The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000127 ! results in development of facial nucleus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021548 ! pons development relationship: RO:0002296 UBERON:0000127 ! results in development of facial nucleus [Term] id: GO:0021782 name: glial cell development def: "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000125 ! results in development of glial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0010001 ! glial cell differentiation relationship: RO:0002296 CL:0000125 ! results in development of glial cell [Term] id: GO:0021783 name: preganglionic parasympathetic fiber development def: "The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion." [GO_REF:0000021, GOC:cjm, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0011930 ! results in development of preganglionic parasympathetic fiber relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007417 ! central nervous system development relationship: part_of GO:0048486 ! parasympathetic nervous system development relationship: RO:0002296 UBERON:0011930 ! results in development of preganglionic parasympathetic fiber [Term] id: GO:0021846 name: cell proliferation in forebrain def: "The creation of greater cell numbers in the forebrain due to cell division of progenitor cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000066 UBERON:0001890 ! occurs in forebrain relationship: BFO:0000066 UBERON:0001890 ! occurs in forebrain relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0030900 ! forebrain development [Term] id: GO:0021863 name: forebrain neuroblast differentiation def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] synonym: "abventricular progenitor cell differentiation" EXACT [PMID:16226447] synonym: "intermediate progenitor cell differentiation" EXACT [PMID:16226447] synonym: "non-surface dividing progenitor cell differentiation" EXACT [PMID:16226447] is_a: GO:0014016 ! neuroblast differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000042 ! results in acquisition of features of forebrain neuroblast relationship: part_of GO:0021872 ! forebrain generation of neurons relationship: RO:0002315 CL:1000042 ! results in acquisition of features of forebrain neuroblast [Term] id: GO:0021872 name: forebrain generation of neurons def: "The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "generation of neurons in forebrain" EXACT [] is_a: GO:0048699 ! generation of neurons relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0030900 ! forebrain development [Term] id: GO:0021879 name: forebrain neuron differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0012001 ! results in acquisition of features of neuron of the forebrain relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021872 ! forebrain generation of neurons relationship: RO:0002315 CL:0012001 ! results in acquisition of features of neuron of the forebrain [Term] id: GO:0021884 name: forebrain neuron development def: "The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021954 ! central nervous system neuron development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0012001 ! results in development of neuron of the forebrain relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021879 ! forebrain neuron differentiation relationship: RO:0002296 CL:0012001 ! results in development of neuron of the forebrain [Term] id: GO:0021885 name: forebrain cell migration def: "The orderly movement of a cell from one site to another at least one of which is located in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0016477 ! cell migration relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0030900 ! forebrain development [Term] id: GO:0021895 name: cerebral cortex neuron differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021879 ! forebrain neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010012 ! results in acquisition of features of cerebral cortex neuron relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002315 CL:0010012 ! results in acquisition of features of cerebral cortex neuron [Term] id: GO:0021903 name: rostrocaudal neural tube patterning def: "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] synonym: "anterior-posterior neural tube patterning" RELATED [GOC:dph] is_a: GO:0009952 ! anterior/posterior pattern specification relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021532 ! neural tube patterning [Term] id: GO:0021905 name: forebrain-midbrain boundary formation def: "The process whose specific outcome is the creation of the forebrain-midbrain boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0048856 ! anatomical structure development is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005075 ! results in formation of anatomical entity forebrain-midbrain boundary relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: RO:0002297 UBERON:0005075 ! results in formation of anatomical entity forebrain-midbrain boundary [Term] id: GO:0021906 name: hindbrain-spinal cord boundary formation def: "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005076 ! results in formation of anatomical entity hindbrain-spinal cord boundary relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: RO:0002297 UBERON:0005076 ! results in formation of anatomical entity hindbrain-spinal cord boundary [Term] id: GO:0021915 name: neural tube development def: "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001049 ! results in development of neural tube relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0007399 ! nervous system development relationship: part_of GO:0043009 ! chordate embryonic development relationship: RO:0002296 UBERON:0001049 ! results in development of neural tube [Term] id: GO:0021953 name: central nervous system neuron differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000029 ! results in acquisition of features of central nervous system neuron relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007417 ! central nervous system development relationship: RO:0002315 CL:2000029 ! results in acquisition of features of central nervous system neuron [Term] id: GO:0021954 name: central nervous system neuron development def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:2000029 ! results in development of central nervous system neuron relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0021953 ! central nervous system neuron differentiation relationship: RO:0002296 CL:2000029 ! results in development of central nervous system neuron [Term] id: GO:0021987 name: cerebral cortex development def: "The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "corticogenesis" NARROW [GOC:bf, PMID:25904839] synonym: "neocortex development" RELATED [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000956 ! results in development of cerebral cortex relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021543 ! pallium development relationship: RO:0002296 UBERON:0000956 ! results in development of cerebral cortex [Term] id: GO:0021990 name: neural plate formation def: "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878932437, ISBN:0878932585, PMID:15806586] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003075 ! results in formation of anatomical entity neural plate relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0001839 ! neural plate morphogenesis relationship: RO:0002297 UBERON:0003075 ! results in formation of anatomical entity neural plate [Term] id: GO:0021999 name: neural plate anterior/posterior regionalization def: "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "neural plate anterior/posterior pattern formation" RELATED [GOC:dph] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0060897 ! neural plate regionalization property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0022008 name: neurogenesis def: "Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] synonym: "nervous system cell generation" EXACT systematic_synonym [] synonym: "neural cell differentiation" RELATED [GOC:BHF, GOC:dph] xref: Wikipedia:Neurogenesis is_a: GO:0030154 ! cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007399 ! nervous system development [Term] id: GO:0022009 name: central nervous system vasculogenesis def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system relationship: RO:0002299 UBERON:0001017 ! results in maturation of central nervous system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21480" xsd:anyURI [Term] id: GO:0022010 name: central nervous system myelination def: "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "myelination in central nervous system" EXACT [] is_a: GO:0032291 ! axon ensheathment in central nervous system is_a: GO:0042552 ! myelination intersection_of: GO:0042552 ! myelination intersection_of: BFO:0000066 UBERON:0001017 ! occurs in central nervous system relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014003 ! oligodendrocyte development [Term] id: GO:0022011 name: myelination in peripheral nervous system def: "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "peripheral nervous system myelination" EXACT [] is_a: GO:0032292 ! peripheral nervous system axon ensheathment is_a: GO:0042552 ! myelination intersection_of: GO:0042552 ! myelination intersection_of: BFO:0000066 UBERON:0000010 ! occurs in peripheral nervous system relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0014044 ! Schwann cell development [Term] id: GO:0022029 name: telencephalon cell migration def: "The orderly movement of a cell from one site to another at least one of which is located in the telencephalon." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021885 ! forebrain cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002344 UBERON:0001893 ! results in transport to from or in telencephalon relationship: part_of GO:0021537 ! telencephalon development relationship: RO:0002344 UBERON:0001893 ! results in transport to from or in telencephalon [Term] id: GO:0022030 name: telencephalon glial cell migration def: "The orderly movement of glial cells through the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0008347 ! glial cell migration is_a: GO:0022029 ! telencephalon cell migration intersection_of: GO:0008347 ! glial cell migration intersection_of: RO:0002344 UBERON:0001893 ! results in transport to from or in telencephalon [Term] id: GO:0022032 name: telencephalon oligodendrocyte cell migration def: "The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0022030 ! telencephalon glial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002344 UBERON:0001893 ! results in transport to from or in telencephalon intersection_of: RO:0004009 CL:0000128 ! has primary input oligodendrocyte relationship: RO:0004009 CL:0000128 ! has primary input oligodendrocyte [Term] id: GO:0022035 name: rhombomere cell migration def: "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15629700] is_a: GO:0021535 ! cell migration in hindbrain intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002344 UBERON:0001892 ! results in transport to from or in rhombomere relationship: part_of GO:0021546 ! rhombomere development relationship: RO:0002344 UBERON:0001892 ! results in transport to from or in rhombomere [Term] id: GO:0022037 name: metencephalon development def: "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001895 ! results in development of metencephalon relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0030902 ! hindbrain development relationship: RO:0002296 UBERON:0001895 ! results in development of metencephalon [Term] id: GO:0022402 name: cell cycle process def: "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." [GOC:isa_complete, GOC:mtg_cell_cycle] subset: gocheck_do_not_annotate subset: goslim_euk_cellular_processes_ribbon is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0007049 ! cell cycle relationship: part_of GO:0007049 ! cell cycle [Term] id: GO:0022404 name: molting cycle process namespace: biological_process def: "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin." [GOC:isa_complete] is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0042303 ! molting cycle [Term] id: GO:0022405 name: hair cycle process namespace: biological_process def: "A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body." [GOC:isa_complete] is_a: GO:0022404 ! molting cycle process relationship: part_of GO:0042633 ! hair cycle [Term] id: GO:0022406 name: membrane docking def: "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:isa_complete, PMID:27875684] subset: goslim_pir is_a: GO:0009987 ! cellular process [Term] id: GO:0022407 name: regulation of cell-cell adhesion def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." [GOC:isa_complete] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098609 ! regulates cell-cell adhesion relationship: RO:0002211 GO:0098609 ! regulates cell-cell adhesion [Term] id: GO:0022408 name: negative regulation of cell-cell adhesion def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "down regulation of cell-cell adhesion" EXACT [] synonym: "down-regulation of cell-cell adhesion" EXACT [] synonym: "downregulation of cell-cell adhesion" EXACT [] synonym: "inhibition of cell-cell adhesion" NARROW [] is_a: GO:0007162 ! negative regulation of cell adhesion is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098609 ! negatively regulates cell-cell adhesion relationship: RO:0002212 GO:0098609 ! negatively regulates cell-cell adhesion [Term] id: GO:0022409 name: positive regulation of cell-cell adhesion def: "Any process that activates or increases the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "activation of cell-cell adhesion" NARROW [] synonym: "stimulation of cell-cell adhesion" NARROW [] synonym: "up regulation of cell-cell adhesion" EXACT [] synonym: "up-regulation of cell-cell adhesion" EXACT [] synonym: "upregulation of cell-cell adhesion" EXACT [] is_a: GO:0022407 ! regulation of cell-cell adhesion is_a: GO:0045785 ! positive regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098609 ! positively regulates cell-cell adhesion relationship: RO:0002213 GO:0098609 ! positively regulates cell-cell adhesion [Term] id: GO:0022411 name: cellular component disassembly alt_id: GO:0071845 def: "A cellular process that results in the breakdown of a cellular component." [GOC:isa_complete] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "cell structure disassembly" EXACT [] synonym: "cellular component disassembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002590 GO:0005575 ! results in disassembly of cellular_component disjoint_from: GO:0022607 ! cellular component assembly relationship: RO:0002590 GO:0005575 ! results in disassembly of cellular_component property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI [Term] id: GO:0022412 name: cellular process involved in reproduction in multicellular organism def: "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." [GOC:isa_complete] synonym: "reproductive cellular process in multicellular organism" EXACT [] is_a: GO:0009987 ! cellular process is_a: GO:0048609 ! multicellular organismal reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: GO:0048609 ! multicellular organismal reproductive process [Term] id: GO:0022414 name: reproductive process namespace: biological_process alt_id: GO:0019952 alt_id: GO:0044702 alt_id: GO:0050876 def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete] subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_plant_ribbon synonym: "single organism reproductive process" RELATED [] xref: Wikipedia:Reproduction is_a: GO:0008150 ! biological process disjoint_from: GO:0044848 ! biological phase property_value: IAO:0000111 "reproductive process" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27054" xsd:anyURI property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl created_by: jl creation_date: 2012-09-19T15:56:06Z [Term] id: GO:0022600 name: digestive system process def: "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, GOC:jid, GOC:mtg_cardio] subset: goslim_generic is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: part_of GO:0007586 ! digestion relationship: part_of GO:0007586 ! digestion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0022602 name: ovulation cycle process def: "A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [GOC:isa_complete] synonym: "estrous cycle process" RELATED [] synonym: "menstrual cycle process" RELATED [] is_a: GO:0022414 ! reproductive process is_a: GO:0048511 ! rhythmic process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0042698 ! ovulation cycle [Term] id: GO:0022603 name: regulation of anatomical structure morphogenesis def: "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." [GOC:mah] synonym: "regulation of morphogenesis" EXACT [] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009653 ! regulates anatomical structure morphogenesis relationship: RO:0002211 GO:0009653 ! regulates anatomical structure morphogenesis [Term] id: GO:0022604 name: regulation of cell morphogenesis def: "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." [GOC:isa_complete] synonym: "negative regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000902 ! regulates cell morphogenesis relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0000902 ! regulates cell morphogenesis [Term] id: GO:0022607 name: cellular component assembly alt_id: GO:0071844 def: "The aggregation, arrangement and bonding together of a cellular component." [GOC:isa_complete] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_pir synonym: "cell structure assembly" EXACT [] synonym: "cellular component assembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0005575 ! results in assembly of cellular_component relationship: part_of GO:0044085 ! cellular component biogenesis relationship: RO:0002588 GO:0005575 ! results in assembly of cellular_component [Term] id: GO:0022612 name: gland morphogenesis def: "The process in which the anatomical structures of a gland are generated and organized." [GOC:isa_complete] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002530 ! results in morphogenesis of gland relationship: part_of GO:0048732 ! gland development relationship: RO:0002298 UBERON:0002530 ! results in morphogenesis of gland [Term] id: GO:0022613 name: ribonucleoprotein complex biogenesis def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." [GOC:isa_complete, GOC:mah] synonym: "ribonucleoprotein complex biogenesis and assembly" EXACT [GOC:mah] synonym: "RNA-protein complex biogenesis" EXACT [GOC:mah] is_a: GO:0044085 ! cellular component biogenesis [Term] id: GO:0022617 name: extracellular matrix disassembly def: "A process that results in the breakdown of the extracellular matrix." [GOC:jid] xref: Reactome:R-HSA-1474228 "Degradation of the extracellular matrix" is_a: GO:0022411 ! cellular component disassembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0031012 ! results in disassembly of extracellular matrix relationship: RO:0002590 GO:0031012 ! results in disassembly of extracellular matrix [Term] id: GO:0022618 name: protein-RNA complex assembly def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." [GOC:jl] subset: goslim_chembl synonym: "ribonucleoprotein complex assembly" EXACT [] synonym: "RNA-protein complex assembly" EXACT [] synonym: "RNP complex assembly" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:1990904 ! results in assembly of ribonucleoprotein complex relationship: part_of GO:0022613 ! ribonucleoprotein complex biogenesis relationship: RO:0002588 GO:1990904 ! results in assembly of ribonucleoprotein complex [Term] id: GO:0022626 name: cytosolic ribosome alt_id: GO:0005830 alt_id: GO:0009281 alt_id: GO:0030871 def: "A ribosome located in the cytosol." [GOC:mtg_sensu] synonym: "70S ribosome" NARROW [] synonym: "80S ribosome" NARROW [] is_a: GO:0005840 ! ribosome intersection_of: GO:0005840 ! ribosome intersection_of: part_of GO:0005829 ! cytosol relationship: part_of GO:0005829 ! cytosol [Term] id: GO:0022804 name: active transmembrane transporter activity def: "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] synonym: "active carrier activity" EXACT [] synonym: "carrier activity" EXACT [] synonym: "permease activity" EXACT [] synonym: "pump activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity [Term] id: GO:0022857 name: transmembrane transporter activity alt_id: GO:0005386 alt_id: GO:0015563 alt_id: GO:0015646 alt_id: GO:0022891 alt_id: GO:0022892 def: "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729] subset: goslim_chembl subset: goslim_drosophila subset: goslim_yeast synonym: "substrate-specific transmembrane transporter activity" RELATED [] synonym: "substrate-specific transporter activity" RELATED [] synonym: "uptake permease activity" RELATED [] synonym: "uptake transmembrane transporter activity" RELATED [] xref: Reactome:R-HSA-1236947 "Egress of internalized antigen to the cytosol via sec61" xref: Reactome:R-HSA-429036 "SLC2A9 transports Fru, Glc, urate" xref: Reactome:R-HSA-434650 "MATEs mediate extrusion of xenobiotics" xref: Reactome:R-HSA-5638209 "Defective SLC2A9 does not transport Fru, Glc, urate" xref: Reactome:R-HSA-5671707 "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA" xref: Reactome:R-HSA-6784434 "An unknown carrier transports cytosolic glyoxylate to the peroxisome" xref: Reactome:R-HSA-6784436 "An unknown carrier transports mitochondrial glyoxylate to the cytosol" xref: Reactome:R-HSA-8954513 "NAASP translocates from mitochondrial matrix to cytosol" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane relationship: part_of GO:0055085 ! transmembrane transport relationship: RO:0002342 GO:0016020 ! results in transport across membrane [Term] id: GO:0022884 name: macromolecule transmembrane transporter activity def: "Enables the transfer of a macromolecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule relationship: RO:0004009 CHEBI:33694 ! has primary input biomacromolecule [Term] id: GO:0022898 name: regulation of transmembrane transporter activity def: "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." [GOC:dph, GOC:mtg_cardio, GOC:mtg_transport] subset: gocheck_obsoletion_candidate is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022857 ! regulates transmembrane transporter activity relationship: RO:0002211 GO:0022857 ! regulates transmembrane transporter activity [Term] id: GO:0023019 name: signal transduction involved in regulation of gene expression def: "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." [GOC:mtg_signal] synonym: "regulation of gene expression as a consequence of signal transmission" RELATED [GOC:bf] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: part_of GO:0010468 ! regulation of gene expression relationship: part_of GO:0010468 ! regulation of gene expression creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023051 name: regulation of signaling def: "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "regulation of signaling process" RELATED [GOC:bf] synonym: "regulation of signalling process" RELATED [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0023052 ! regulates signaling relationship: RO:0002211 GO:0023052 ! regulates signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023052 name: signaling alt_id: GO:0023046 alt_id: GO:0044700 def: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe subset: goslim_prokaryote subset: goslim_prokaryote_ribbon subset: goslim_yeast synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] synonym: "signalling process" RELATED [GOC:mah] synonym: "single organism signaling" RELATED [] is_a: GO:0050789 ! regulation of biological process created_by: jl creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023056 name: positive regulation of signaling def: "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "positive regulation of signaling process" RELATED [GOC:bf] synonym: "positive regulation of signalling process" EXACT [GOC:mah] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0023052 ! positively regulates signaling relationship: RO:0002213 GO:0023052 ! positively regulates signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023057 name: negative regulation of signaling def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "negative regulation of signaling process" RELATED [GOC:bf] synonym: "negative regulation of signalling process" RELATED [GOC:mah] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0023052 ! negatively regulates signaling relationship: RO:0002212 GO:0023052 ! negatively regulates signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023061 name: signal release def: "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." [GOC:mtg_signal] synonym: "signal secretion" EXACT [GOC:bf] is_a: GO:0032940 ! secretion by cell intersection_of: GO:0032940 ! secretion by cell intersection_of: part_of GO:0007267 ! cell-cell signaling relationship: part_of GO:0007267 ! cell-cell signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0030001 name: metal ion transport alt_id: GO:0070838 alt_id: GO:0070839 def: "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "divalent metal ion export" NARROW [] synonym: "divalent metal ion transport" NARROW [] synonym: "heavy metal ion transport" NARROW [] synonym: "metal ion export" NARROW [] is_a: GO:0006812 ! monoatomic cation transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23033" xsd:anyURI created_by: mah creation_date: 2009-07-31T01:07:46Z [Term] id: GO:0030003 name: intracellular monoatomic cation homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." [GOC:ceb, GOC:mah] synonym: "cellular cation homeostasis" BROAD [] synonym: "cellular monoatomic cation homeostasis" EXACT [] is_a: GO:0006873 ! intracellular monoatomic ion homeostasis is_a: GO:0055080 ! monoatomic cation homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: RO:0002332 CHEBI:23906 ! regulates levels of monoatomic cation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] id: GO:0030010 name: establishment of cell polarity alt_id: GO:0000283 alt_id: GO:0030468 def: "The specification and formation of anisotropic intracellular organization or cell growth patterns." [GOC:mah] synonym: "bud site selection/establishment of cell polarity" NARROW [] synonym: "cell polarization" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030016 name: myofibril def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194] xref: Wikipedia:Myofibril is_a: GO:0043292 ! contractile muscle fiber intersection_of: GO:0043292 ! contractile muscle fiber intersection_of: part_of CL:0000737 ! striated muscle cell relationship: part_of CL:0000737 ! striated muscle cell [Term] id: GO:0030017 name: sarcomere def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194] xref: Wikipedia:Sarcomere is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0030016 ! myofibril [Term] id: GO:0030029 name: actin filament-based process def: "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." [GOC:mah] synonym: "microfilament-based process" RELATED [] is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002608 GO:0005884 ! process has causal agent actin filament relationship: RO:0002608 GO:0005884 ! process has causal agent actin filament [Term] id: GO:0030030 name: cell projection organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:16318917] subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042995 ! results in organization of cell projection relationship: RO:0002592 GO:0042995 ! results in organization of cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI [Term] id: GO:0030031 name: cell projection assembly def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, PMID:18391171] synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0042995 ! results in assembly of cell projection relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002588 GO:0042995 ! results in assembly of cell projection [Term] id: GO:0030033 name: microvillus assembly def: "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah, ISBN:0815316194] synonym: "microvillus biogenesis" RELATED [GOC:mah] is_a: GO:0032528 ! microvillus organization is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005902 ! results in assembly of microvillus relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002588 GO:0005902 ! results in assembly of microvillus [Term] id: GO:0030036 name: actin cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_pombe synonym: "actin cytoskeleton organisation" EXACT [] synonym: "actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] synonym: "actin modulating activity" RELATED [] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0030029 ! actin filament-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0015629 ! results in organization of actin cytoskeleton relationship: RO:0002592 GO:0015629 ! results in organization of actin cytoskeleton property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI [Term] id: GO:0030048 name: actin filament-based movement def: "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GOC:BHF, GOC:mah] is_a: GO:0030029 ! actin filament-based process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0030050 name: vesicle transport along actin filament def: "Movement of a vesicle along an actin filament, mediated by motor proteins." [GOC:mah] is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005884 ! results in transport along actin filament intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0030054 name: cell junction def: "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." [GOC:aruk, GOC:bc, GOC:mah, ISBN:0198506732, PMID:26820516, PMID:28096264] subset: goslim_agr subset: goslim_drosophila subset: goslim_flybase_ribbon xref: Wikipedia:Cell_junction is_a: GO:0110165 ! cellular anatomical structure property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0030072 name: peptide hormone secretion def: "The regulated release of a peptide hormone from a cell." [GOC:mah] is_a: GO:0002790 ! peptide secretion is_a: GO:0046879 ! hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:25905 ! has primary input peptide hormone relationship: RO:0004009 CHEBI:25905 ! has primary input peptide hormone [Term] id: GO:0030073 name: insulin secretion def: "The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732] is_a: GO:0009306 ! protein secretion is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 PR:000009054 ! has primary input preproinsulin relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0004009 PR:000009054 ! has primary input preproinsulin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/11255" xsd:anyURI [Term] id: GO:0030097 name: hemopoiesis def: "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732] synonym: "blood cell biosynthesis" EXACT [] synonym: "blood cell formation" EXACT [] synonym: "haemopoiesis" EXACT [] synonym: "hematopoiesis" EXACT [] xref: Wikipedia:Haematopoiesis is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000988 ! results in development of hematopoietic cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 CL:0000988 ! results in development of hematopoietic cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI [Term] id: GO:0030098 name: lymphocyte differentiation alt_id: GO:0046650 def: "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "lymphocyte cell differentiation" EXACT [] synonym: "lymphocyte development" RELATED [GOC:add] synonym: "lymphocytic blood cell differentiation" EXACT [] is_a: GO:0046649 ! lymphocyte activation is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000542 ! results in acquisition of features of lymphocyte relationship: RO:0002315 CL:0000542 ! results in acquisition of features of lymphocyte [Term] id: GO:0030099 name: myeloid cell differentiation def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." [GOC:add, ISBN:0781735149] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000763 ! results in acquisition of features of myeloid cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0030097 ! hemopoiesis relationship: RO:0002315 CL:0000763 ! results in acquisition of features of myeloid cell [Term] id: GO:0030100 name: regulation of endocytosis def: "Any process that modulates the frequency, rate or extent of endocytosis." [GOC:go_curators] is_a: GO:0051128 ! regulation of cellular component organization is_a: GO:0060627 ! regulation of vesicle-mediated transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006897 ! regulates endocytosis relationship: RO:0002211 GO:0006897 ! regulates endocytosis [Term] id: GO:0030133 name: transport vesicle def: "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." [GOC:mah, PMID:22160157] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'. synonym: "constitutive secretory pathway transport vesicle" EXACT [] synonym: "Golgi to vacuole transport vesicle" NARROW [] synonym: "Golgi-vacuole transport vesicle" NARROW [] synonym: "secretory vesicle" RELATED [] xref: NIF_Subcellular:sao885490876 is_a: GO:0031410 ! cytoplasmic vesicle relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0030141 name: secretory granule def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198506732] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'. synonym: "secretory vesicle" BROAD [] is_a: GO:0099503 ! secretory vesicle relationship: part_of GO:0012505 ! endomembrane system property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0030154 name: cell differentiation def: "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant subset: goslim_plant_ribbon xref: Wikipedia:Cellular_differentiation is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0048869 ! cellular developmental process intersection_of: RO:0002315 CL:0000000 ! results in acquisition of features of cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002315 CL:0000000 ! results in acquisition of features of cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0030155 name: regulation of cell adhesion def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." [GOC:mah] synonym: "cell adhesion receptor regulator activity" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007155 ! regulates cell adhesion relationship: RO:0002211 GO:0007155 ! regulates cell adhesion [Term] id: GO:0030163 name: protein catabolic process alt_id: GO:0044254 alt_id: GO:0044257 def: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah] comment: This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children. subset: goslim_candida subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote synonym: "cellular protein breakdown" EXACT [] synonym: "cellular protein catabolic process" EXACT [] synonym: "cellular protein catabolism" EXACT [] synonym: "cellular protein degradation" EXACT [] synonym: "multicellular organismal protein catabolic process" NARROW [] synonym: "pheromone catabolic process" RELATED [] synonym: "pheromone catabolism" RELATED [] synonym: "protein breakdown" EXACT [] synonym: "protein catabolism" EXACT [] synonym: "protein degradation" EXACT [] xref: Wikipedia:Protein_catabolism is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0019538 ! protein metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0004009 PR:000000001 ! has primary input protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0030182 name: neuron differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron." [GOC:mah] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000540 ! results in acquisition of features of neuron relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048699 ! generation of neurons relationship: RO:0002315 CL:0000540 ! results in acquisition of features of neuron [Term] id: GO:0030198 name: extracellular matrix organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." [GOC:mah] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic synonym: "extracellular matrix organisation" EXACT [] synonym: "extracellular matrix organization and biogenesis" RELATED [GOC:mah] xref: Reactome:R-HSA-1474244 "Extracellular matrix organization" is_a: GO:0043062 ! extracellular structure organization is_a: GO:0045229 ! external encapsulating structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031012 ! results in organization of extracellular matrix relationship: RO:0002592 GO:0031012 ! results in organization of extracellular matrix [Term] id: GO:0030199 name: collagen fibril organization def: "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." [GOC:mah, ISBN:0815316194] synonym: "collagen fibril organisation" EXACT [] synonym: "fibrillar collagen organization" EXACT [GOC:mah] xref: Reactome:R-HSA-1474290 "Collagen formation" xref: Reactome:R-HSA-2214320 "Anchoring fibril formation" xref: Reactome:R-HSA-2243919 "Crosslinking of collagen fibrils" is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0098643 ! results in organization of fibrillar collagen relationship: RO:0002592 GO:0098643 ! results in organization of fibrillar collagen property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0030203 name: glycosaminoglycan metabolic process def: "The chemical reactions and pathways involving glycosaminoglycans, any of a group of linear polysaccharides composed of repeating disaccharide units." [PMID:38500384] synonym: "glycosaminoglycan metabolism" EXACT [] xref: Reactome:R-HSA-1630316 "Glycosaminoglycan metabolism" is_a: GO:0006022 ! aminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:18085 ! has primary input or output glycosaminoglycan relationship: RO:0004007 CHEBI:18085 ! has primary input or output glycosaminoglycan property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29745" xsd:anyURI [Term] id: GO:0030212 name: hyaluronan metabolic process def: "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine." [PMID:33171800, PMID:35536932] synonym: "hyaluronan metabolism" EXACT [] xref: Reactome:R-HSA-2142845 "Hyaluronan metabolism" is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:16336 ! has primary input or output hyaluronic acid relationship: RO:0004007 CHEBI:16336 ! has primary input or output hyaluronic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29745" xsd:anyURI [Term] id: GO:0030213 name: hyaluronan biosynthetic process def: "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine." [PMID:33171800, PMID:35536932] synonym: "hyaluronan anabolism" EXACT [] synonym: "hyaluronan biosynthesis" EXACT [] synonym: "hyaluronan formation" EXACT [] synonym: "hyaluronan synthesis" EXACT [] xref: Reactome:R-HSA-2142850 "Hyaluronan biosynthesis and export" is_a: GO:0006024 ! glycosaminoglycan biosynthetic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:16336 ! has primary output hyaluronic acid relationship: RO:0004008 CHEBI:16336 ! has primary output hyaluronic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29745" xsd:anyURI [Term] id: GO:0030214 name: hyaluronan catabolic process def: "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine." [PMID:33171800, PMID:35536932] synonym: "hyaluronan breakdown" EXACT [] synonym: "hyaluronan catabolism" EXACT [] synonym: "hyaluronan degradation" EXACT [] xref: MetaCyc:PWY-7645 xref: Reactome:R-HSA-2160916 "Hyaluronan uptake and degradation" is_a: GO:0006027 ! glycosaminoglycan catabolic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:16336 ! has primary input hyaluronic acid relationship: RO:0004009 CHEBI:16336 ! has primary input hyaluronic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27107" xsd:anyURI [Term] id: GO:0030217 name: T cell differentiation alt_id: GO:0042112 alt_id: GO:0046652 def: "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." [GO_REF:0000022, GOC:jid, GOC:mah] comment: Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "T cell development" RELATED [GOC:add] synonym: "T lymphocyte differentiation" EXACT [] synonym: "T-cell differentiation" EXACT [] synonym: "T-lymphocyte differentiation" EXACT [] is_a: GO:0030098 ! lymphocyte differentiation is_a: GO:0042110 ! T cell activation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000084 ! results in acquisition of features of T cell relationship: RO:0002315 CL:0000084 ! results in acquisition of features of T cell [Term] id: GO:0030218 name: erythrocyte differentiation def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." [GOC:mah] synonym: "erythrocyte cell differentiation" EXACT [] synonym: "erythropoiesis" EXACT [GOC:add, GOC:dph] synonym: "RBC differentiation" EXACT [CL:0000232] synonym: "red blood cell differentiation" EXACT [CL:0000232] xref: Wikipedia:Erythropoiesis is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000232 ! results in acquisition of features of erythrocyte relationship: part_of GO:0034101 ! erythrocyte homeostasis relationship: RO:0002315 CL:0000232 ! results in acquisition of features of erythrocyte [Term] id: GO:0030219 name: megakaryocyte differentiation def: "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." [GOC:mah] synonym: "megakaryocyte cell differentiation" EXACT [] is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000556 ! results in acquisition of features of megakaryocyte relationship: RO:0002315 CL:0000556 ! results in acquisition of features of megakaryocyte [Term] id: GO:0030239 name: myofibril assembly def: "Formation of myofibrils, the repeating units of striated muscle." [GOC:mah] is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0031032 ! actomyosin structure organization is_a: GO:0097435 ! supramolecular fiber organization is_a: GO:0140694 ! membraneless organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0030016 ! results in assembly of myofibril relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0055002 ! striated muscle cell development relationship: RO:0002588 GO:0030016 ! results in assembly of myofibril [Term] id: GO:0030261 name: chromosome condensation alt_id: GO:0000068 def: "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:mah, ISBN:0815316194] synonym: "DNA condensation" BROAD [Wikipedia:DNA_condensation] synonym: "eukaryotic chromosome condensation" EXACT [GOC:bf] synonym: "nuclear chromosome condensation" EXACT [GOC:bf] is_a: GO:0051276 ! chromosome organization [Term] id: GO:0030262 name: apoptotic nuclear changes def: "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." [GOC:mah, GOC:mtg_apoptosis] synonym: "apoptotic nuclear change" NARROW [] is_a: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0030263 name: apoptotic chromosome condensation def: "The compaction of chromatin during apoptosis." [GOC:mah] synonym: "pyknosis" EXACT [] xref: Wikipedia:Pyknosis is_a: GO:0030261 ! chromosome condensation relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: part_of GO:0030262 ! apoptotic nuclear changes property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0030264 name: nuclear fragmentation involved in apoptotic nuclear change def: "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976] synonym: "apoptotic nuclear fragmentation" EXACT [] synonym: "nuclear fragmentation during apoptosis" RELATED [GOC:dph, GOC:tb] synonym: "nucleus fragmentation" EXACT [] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: part_of GO:0030262 ! apoptotic nuclear changes relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: part_of GO:0030262 ! apoptotic nuclear changes property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0030278 name: regulation of ossification def: "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "regulation of bone biosynthesis" EXACT [] synonym: "regulation of bone formation" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001503 ! regulates ossification relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0001503 ! regulates ossification [Term] id: GO:0030279 name: negative regulation of ossification def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "down regulation of ossification" EXACT [] synonym: "down-regulation of ossification" EXACT [] synonym: "downregulation of ossification" EXACT [] synonym: "inhibition of ossification" NARROW [] synonym: "negative regulation of bone biosynthesis" EXACT [] synonym: "negative regulation of bone formation" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001503 ! negatively regulates ossification relationship: RO:0002212 GO:0001503 ! negatively regulates ossification [Term] id: GO:0030307 name: positive regulation of cell growth def: "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "activation of cell growth" NARROW [] synonym: "stimulation of cell growth" NARROW [] synonym: "up regulation of cell growth" EXACT [] synonym: "up-regulation of cell growth" EXACT [] synonym: "upregulation of cell growth" EXACT [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016049 ! positively regulates cell growth relationship: RO:0002213 GO:0016049 ! positively regulates cell growth [Term] id: GO:0030308 name: negative regulation of cell growth def: "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "down regulation of cell growth" EXACT [] synonym: "down-regulation of cell growth" EXACT [] synonym: "downregulation of cell growth" EXACT [] synonym: "inhibition of cell growth" NARROW [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016049 ! negatively regulates cell growth relationship: RO:0002212 GO:0016049 ! negatively regulates cell growth [Term] id: GO:0030312 name: external encapsulating structure def: "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." [GOC:go_curators] comment: The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_plant is_a: GO:0110165 ! cellular anatomical structure relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0030317 name: flagellated sperm motility alt_id: GO:0097724 alt_id: GO:1905419 def: "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm." [GO_REF:0000060, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:26680031] synonym: "flagellated sperm movement" EXACT [] synonym: "sperm flagellum movement" EXACT [GOC:cilia, GOC:krc] synonym: "sperm flagellum movement involved in flagellated sperm motility" EXACT [] synonym: "sperm flagellum movement involved in flagellated sperm movement" EXACT [GOC:TermGenie] synonym: "sperm motility" BROAD [] synonym: "sperm movement" BROAD [] xref: Wikipedia:Sperm_motility is_a: GO:0060285 ! cilium-dependent cell motility is_a: GO:0060294 ! cilium movement involved in cell motility is_a: GO:0097722 ! sperm motility intersection_of: GO:0060285 ! cilium-dependent cell motility intersection_of: RO:0002565 CL:0000019 ! results in movement of sperm property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0030323 name: respiratory tube development def: "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." [GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000117 ! results in development of respiratory tube relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0000117 ! results in development of respiratory tube [Term] id: GO:0030324 name: lung development def: "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:jid, UBERON:0002048] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002048 ! results in development of lung relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030323 ! respiratory tube development relationship: part_of GO:0060541 ! respiratory system development relationship: RO:0002296 UBERON:0002048 ! results in development of lung [Term] id: GO:0030334 name: regulation of cell migration def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016477 ! regulates cell migration relationship: RO:0002211 GO:0016477 ! regulates cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0030335 name: positive regulation of cell migration def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "activation of cell migration" NARROW [] synonym: "stimulation of cell migration" NARROW [] synonym: "up regulation of cell migration" EXACT [] synonym: "up-regulation of cell migration" EXACT [] synonym: "upregulation of cell migration" EXACT [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016477 ! positively regulates cell migration relationship: RO:0002213 GO:0016477 ! positively regulates cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0030336 name: negative regulation of cell migration def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "down regulation of cell migration" EXACT [] synonym: "down-regulation of cell migration" EXACT [] synonym: "downregulation of cell migration" EXACT [] synonym: "inhibition of cell migration" NARROW [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016477 ! negatively regulates cell migration relationship: RO:0002212 GO:0016477 ! negatively regulates cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0030397 name: membrane disassembly def: "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." [GOC:mah] synonym: "membrane breakdown" EXACT [] synonym: "membrane catabolism" EXACT [] synonym: "membrane degradation" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0016020 ! results in disassembly of membrane relationship: RO:0002590 GO:0016020 ! results in disassembly of membrane [Term] id: GO:0030421 name: defecation def: "The expulsion of feces from the rectum." [GOC:mah] xref: Wikipedia:Defecation is_a: GO:0007588 ! excretion is_a: GO:0022600 ! digestive system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0030424 name: axon def: "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." [GOC:nln, ISBN:0198506732] xref: NIF_Subcellular:sao1770195789 xref: Wikipedia:Axon is_a: GO:0043005 ! neuron projection [Term] id: GO:0030432 name: peristalsis def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards." [ISBN:0198506732] xref: Wikipedia:Peristalsis is_a: GO:0014821 ! phasic smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0030473 name: nuclear migration along microtubule alt_id: GO:0000065 def: "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." [GOC:mah, GOC:sgd_curators] synonym: "microtubule cytoskeleton-dependent nuclear positioning" EXACT [] synonym: "microtubule cytoskeleton-dependent nucleus positioning" EXACT [] synonym: "microtubule-dependent nuclear positioning" EXACT [] synonym: "microtubule-dependent nucleus positioning" EXACT [] synonym: "microtubule-mediated nuclear migration" EXACT [] synonym: "nuclear migration, microtubule-mediated" EXACT [] synonym: "nuclear movement, microtubule-mediated" BROAD [] synonym: "nucleus migration" BROAD [] synonym: "transport of nucleus by microtubules" EXACT [] synonym: "transport of nucleus, microtubule-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0072384 ! organelle transport along microtubule intersection_of: GO:0007097 ! nuclear migration intersection_of: RO:0002341 GO:0015630 ! results in transport along microtubule cytoskeleton relationship: RO:0002341 GO:0015630 ! results in transport along microtubule cytoskeleton [Term] id: GO:0030485 name: smooth muscle contractile fiber def: "The contractile fiber of smooth muscle cells." [GOC:mah] is_a: GO:0043292 ! contractile muscle fiber intersection_of: GO:0043292 ! contractile muscle fiber intersection_of: part_of CL:0000192 ! smooth muscle cell relationship: part_of CL:0000192 ! smooth muscle cell [Term] id: GO:0030539 name: male genitalia development def: "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure." [GOC:ems, ISBN:0140512888] synonym: "male genital development" EXACT [] is_a: GO:0048806 ! genitalia development is_a: GO:0061458 ! reproductive system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000079 ! results in development of male reproductive system relationship: part_of GO:0046661 ! male sex differentiation relationship: RO:0002296 UBERON:0000079 ! results in development of male reproductive system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0030540 name: female genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure." [GOC:mah] synonym: "female genital development" EXACT [] is_a: GO:0048806 ! genitalia development relationship: part_of GO:0046660 ! female sex differentiation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0030573 name: bile acid catabolic process alt_id: GO:0019613 def: "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid 7alpha-dehydroxylation pathway" NARROW [] synonym: "bile acid breakdown" EXACT [] synonym: "bile acid catabolism" EXACT [] synonym: "bile acid degradation" EXACT [] synonym: "cholate catabolic process" NARROW [] is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:36235 ! has primary input bile acid anion relationship: RO:0004009 CHEBI:36235 ! has primary input bile acid anion [Term] id: GO:0030574 name: collagen catabolic process def: "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." [GOC:mah, ISBN:0815316194] synonym: "collagen breakdown" EXACT [] synonym: "collagen catabolism" EXACT [] synonym: "collagen degradation" EXACT [] xref: Reactome:R-HSA-1442490 "Collagen degradation" is_a: GO:0009056 ! catabolic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 GO:0005581 ! has primary input collagen trimer relationship: RO:0004009 GO:0005581 ! has primary input collagen trimer [Term] id: GO:0030642 name: intracellular sulfate ion homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell." [GOC:mah, PMID:24193406] synonym: "cellular sulfate ion homeostasis" EXACT [] synonym: "sulphate ion homeostasis" BROAD [] is_a: GO:0055063 ! sulfate ion homeostasis is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis intersection_of: RO:0002332 CHEBI:16189 ! regulates levels of sulfate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24514" xsd:anyURI [Term] id: GO:0030658 name: transport vesicle membrane def: "The lipid bilayer surrounding a transport vesicle." [GOC:mah] synonym: "constitutive secretory pathway transport vesicle membrane" EXACT [] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0030133 ! transport vesicle relationship: bounding_layer_of GO:0030133 ! transport vesicle relationship: part_of GO:0030133 ! transport vesicle [Term] id: GO:0030659 name: cytoplasmic vesicle membrane def: "The lipid bilayer surrounding a cytoplasmic vesicle." [GOC:mah] is_a: GO:0012506 ! vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0031410 ! cytoplasmic vesicle relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0030660 name: Golgi-associated vesicle membrane def: "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." [GOC:mah] synonym: "Golgi vesicle membrane" RELATED [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005798 ! Golgi-associated vesicle relationship: bounding_layer_of GO:0005798 ! Golgi-associated vesicle relationship: part_of GO:0005798 ! Golgi-associated vesicle [Term] id: GO:0030667 name: secretory granule membrane def: "The lipid bilayer surrounding a secretory granule." [GOC:mah] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0030141 ! secretory granule relationship: bounding_layer_of GO:0030141 ! secretory granule relationship: part_of GO:0030141 ! secretory granule property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0030705 name: cytoskeleton-dependent intracellular transport def: "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." [GOC:mah] subset: goslim_chembl subset: goslim_drosophila is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0099513 ! results in transport along polymeric cytoskeletal fiber relationship: RO:0002341 GO:0099513 ! results in transport along polymeric cytoskeletal fiber [Term] id: GO:0030718 name: germ-line stem cell population maintenance def: "Any process by which an organism or tissue maintains a population of germ-line stem cells." [ISBN:0879694238] is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000014 ! acts on population of germ line stem cell relationship: RO:0012003 CL:0000014 ! acts on population of germ line stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0030720 name: oocyte localization involved in germarium-derived egg chamber formation def: "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." [GOC:mtg_sensu, PMID:10449356] synonym: "establishment and maintenance of oocyte localization in egg chamber" EXACT [] synonym: "establishment and maintenance of oocyte position during oogenesis" EXACT [] synonym: "oocyte localisation involved in germarium-derived egg chamber formation" EXACT [GOC:mah] synonym: "oocyte localization during germarium-derived egg chamber formation" RELATED [GOC:dph, GOC:tb] synonym: "oocyte localization during oogenesis" RELATED [] synonym: "oocyte positioning during oogenesis" NARROW [] synonym: "oogenesis, establishment and maintenance of oocyte localization" EXACT [] synonym: "oogenesis, oocyte localization" EXACT [] is_a: GO:0051674 ! localization of cell intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 CL:0000023 ! has primary input oocyte relationship: in_taxon NCBITaxon:50557 ! Insecta relationship: part_of GO:0007293 ! germarium-derived egg chamber formation relationship: RO:0004009 CL:0000023 ! has primary input oocyte [Term] id: GO:0030855 name: epithelial cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." [GOC:ecd, PMID:11839751] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000066 ! results in acquisition of features of epithelial cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0060429 ! epithelium development relationship: RO:0002315 CL:0000066 ! results in acquisition of features of epithelial cell [Term] id: GO:0030856 name: regulation of epithelial cell differentiation def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030855 ! regulates epithelial cell differentiation relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0030855 ! regulates epithelial cell differentiation [Term] id: GO:0030857 name: negative regulation of epithelial cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "down regulation of epithelial cell differentiation" EXACT [] synonym: "down-regulation of epithelial cell differentiation" EXACT [] synonym: "downregulation of epithelial cell differentiation" EXACT [] synonym: "inhibition of epithelial cell differentiation" NARROW [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030855 ! negatively regulates epithelial cell differentiation relationship: RO:0002212 GO:0030855 ! negatively regulates epithelial cell differentiation [Term] id: GO:0030858 name: positive regulation of epithelial cell differentiation def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "activation of epithelial cell differentiation" NARROW [] synonym: "stimulation of epithelial cell differentiation" NARROW [] synonym: "up regulation of epithelial cell differentiation" EXACT [] synonym: "up-regulation of epithelial cell differentiation" EXACT [] synonym: "upregulation of epithelial cell differentiation" EXACT [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030855 ! positively regulates epithelial cell differentiation relationship: RO:0002213 GO:0030855 ! positively regulates epithelial cell differentiation [Term] id: GO:0030879 name: mammary gland development namespace: biological_process def: "The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages." [PMID:9576833] synonym: "mammogenesis" NARROW [GOC:dph] is_a: GO:0048732 ! gland development [Term] id: GO:0030900 name: forebrain development def: "The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." [PMID:4975589, PMID:4992177] synonym: "prosencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001890 ! results in development of forebrain relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0007420 ! brain development relationship: RO:0002296 UBERON:0001890 ! results in development of forebrain [Term] id: GO:0030901 name: midbrain development def: "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." [PMID:4975589, PMID:4992177] synonym: "mesencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001891 ! results in development of midbrain relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0007420 ! brain development relationship: RO:0002296 UBERON:0001891 ! results in development of midbrain [Term] id: GO:0030902 name: hindbrain development def: "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." [PMID:4975589, PMID:4992177] synonym: "rhombencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002028 ! results in development of hindbrain relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007420 ! brain development relationship: RO:0002296 UBERON:0002028 ! results in development of hindbrain [Term] id: GO:0030903 name: notochord development def: "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:dgh] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002328 ! results in development of notochord relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002296 UBERON:0002328 ! results in development of notochord [Term] id: GO:0030910 name: olfactory placode formation def: "The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:dgh] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003050 ! results in formation of anatomical entity olfactory placode relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0043584 ! nose development relationship: part_of GO:0071699 ! olfactory placode morphogenesis relationship: RO:0002297 UBERON:0003050 ! results in formation of anatomical entity olfactory placode [Term] id: GO:0030916 name: otic vesicle formation def: "The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:dgh] synonym: "otocyst biosynthesis" EXACT [] synonym: "otocyst formation" EXACT [] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003051 ! results in formation of anatomical entity ear vesicle relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0071600 ! otic vesicle morphogenesis relationship: RO:0002297 UBERON:0003051 ! results in formation of anatomical entity ear vesicle [Term] id: GO:0030917 name: midbrain-hindbrain boundary development def: "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." [GOC:dgh] synonym: "isthmic organizer development" EXACT [] synonym: "isthmomesencephalic boundary development" EXACT [] synonym: "isthmus development" EXACT [] synonym: "MHB development" EXACT [] synonym: "midbrain-hindbrain orgainizer development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003052 ! results in development of midbrain-hindbrain boundary relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007420 ! brain development relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: RO:0002296 UBERON:0003052 ! results in development of midbrain-hindbrain boundary [Term] id: GO:0030936 name: transmembrane collagen trimer def: "Any collagen trimer that passes through a lipid bilayer membrane." [PMID:21421911] synonym: "MACIT" EXACT [ISBN:0198599587] is_a: GO:0005581 ! collagen trimer is_a: GO:0098797 ! plasma membrane protein complex intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0005886 ! plasma membrane [Term] id: GO:0030951 name: establishment or maintenance of microtubule cytoskeleton polarity def: "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." [GOC:mah] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity [Term] id: GO:0030952 name: establishment or maintenance of cytoskeleton polarity def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." [GOC:mah] synonym: "cytoskeleton polarization" RELATED [] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030990 name: intraciliary transport particle def: "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." [GOC:cilia, GOC:kmv, PMID:14570576, PMID:22118932, PMID:23945166] comment: Note that we deem cilia and microtubule-based flagella to be equivalent. subset: goslim_pir synonym: "IFT complex" RELATED [] synonym: "intraflagellar transport complex" EXACT [] synonym: "intraflagellar transport particle" EXACT [] is_a: GO:0032991 ! protein-containing complex relationship: capable_of_part_of GO:0035735 ! intraciliary transport involved in cilium assembly [Term] id: GO:0031012 name: extracellular matrix alt_id: GO:0005578 def: "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, PMID:21123617, PMID:28089324, PMID:33605520] subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_pir subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 xref: Wikipedia:Extracellular_matrix is_a: GO:0030312 ! external encapsulating structure disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle [Term] id: GO:0031016 name: pancreas development def: "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones." [GOC:cvs] xref: Wikipedia:Pancreas is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001264 ! results in development of pancreas relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0001264 ! results in development of pancreas property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23777" xsd:anyURI [Term] id: GO:0031017 name: exocrine pancreas development def: "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells." [GOC:cvs] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000017 ! results in development of exocrine pancreas relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031016 ! pancreas development relationship: part_of GO:0035272 ! exocrine system development relationship: part_of GO:0055123 ! digestive system development relationship: RO:0002296 UBERON:0000017 ! results in development of exocrine pancreas [Term] id: GO:0031018 name: endocrine pancreas development def: "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin." [GOC:cvs] xref: Reactome:R-HSA-186712 "Regulation of beta-cell development" is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000016 ! results in development of endocrine pancreas relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031016 ! pancreas development relationship: part_of GO:0035270 ! endocrine system development relationship: RO:0002296 UBERON:0000016 ! results in development of endocrine pancreas [Term] id: GO:0031022 name: nuclear migration along microfilament def: "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." [GOC:mah] synonym: "nuclear migration, microfilament-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport intersection_of: GO:0007097 ! nuclear migration intersection_of: RO:0002341 GO:0005884 ! results in transport along actin filament [Term] id: GO:0031032 name: actomyosin structure organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." [GOC:dph, GOC:jl, GOC:mah] comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins. synonym: "actomyosin organization" EXACT [] synonym: "actomyosin structure organisation" EXACT [] synonym: "actomyosin structure organization and biogenesis" RELATED [GOC:mah] is_a: GO:0030036 ! actin cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0042641 ! results in organization of actomyosin relationship: RO:0002592 GO:0042641 ! results in organization of actomyosin [Term] id: GO:0031045 name: dense core granule def: "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." [NIF_Subcellular:sao772007592, PMID:14690495] synonym: "dense core vesicle" EXACT syngo_official_label [GOC:kmv] xref: NIF_Subcellular:sao772007592 is_a: GO:0030141 ! secretory granule property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0031076 name: embryonic camera-type eye development def: "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." [GOC:mah, GOC:mtg_sensu] synonym: "embryonic eye development" EXACT [] is_a: GO:0043010 ! camera-type eye development is_a: GO:0048568 ! embryonic organ development [Term] id: GO:0031090 name: organelle membrane def: "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah] synonym: "intracellular membrane" RELATED [NIF_Subcellular:sao830981606] xref: NIF_Subcellular:sao830981606 is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031109 name: microtubule polymerization or depolymerization def: "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] synonym: "microtubule dynamics" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI [Term] id: GO:0031110 name: regulation of microtubule polymerization or depolymerization def: "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031109 ! regulates microtubule polymerization or depolymerization relationship: RO:0002211 GO:0031109 ! regulates microtubule polymerization or depolymerization [Term] id: GO:0031111 name: negative regulation of microtubule polymerization or depolymerization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "down-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "downregulation of microtubule polymerization or depolymerization" EXACT [] synonym: "inhibition of microtubule polymerization or depolymerization" NARROW [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051494 ! negative regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031109 ! negatively regulates microtubule polymerization or depolymerization relationship: RO:0002212 GO:0031109 ! negatively regulates microtubule polymerization or depolymerization [Term] id: GO:0031112 name: positive regulation of microtubule polymerization or depolymerization def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "activation of microtubule polymerization or depolymerization" NARROW [] synonym: "stimulation of microtubule polymerization or depolymerization" NARROW [] synonym: "up regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "up-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "upregulation of microtubule polymerization or depolymerization" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051495 ! positive regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0031109 ! positively regulates microtubule polymerization or depolymerization relationship: RO:0002213 GO:0031109 ! positively regulates microtubule polymerization or depolymerization [Term] id: GO:0031113 name: regulation of microtubule polymerization def: "Any process that modulates the frequency, rate or extent of microtubule polymerization." [GOC:mah] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0032271 ! regulation of protein polymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046785 ! regulates microtubule polymerization relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0046785 ! regulates microtubule polymerization [Term] id: GO:0031114 name: regulation of microtubule depolymerization def: "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "regulation of microtubule disassembly" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:1901879 ! regulation of protein depolymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007019 ! regulates microtubule depolymerization relationship: RO:0002211 GO:0007019 ! regulates microtubule depolymerization [Term] id: GO:0031115 name: negative regulation of microtubule polymerization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization" EXACT [] synonym: "down-regulation of microtubule polymerization" EXACT [] synonym: "downregulation of microtubule polymerization" EXACT [] synonym: "inhibition of microtubule polymerization" NARROW [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032272 ! negative regulation of protein polymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046785 ! negatively regulates microtubule polymerization relationship: RO:0002212 GO:0046785 ! negatively regulates microtubule polymerization [Term] id: GO:0031116 name: positive regulation of microtubule polymerization def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "activation of microtubule polymerization" NARROW [] synonym: "stimulation of microtubule polymerization" NARROW [] synonym: "up regulation of microtubule polymerization" EXACT [] synonym: "up-regulation of microtubule polymerization" EXACT [] synonym: "upregulation of microtubule polymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032273 ! positive regulation of protein polymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046785 ! positively regulates microtubule polymerization relationship: RO:0002213 GO:0046785 ! positively regulates microtubule polymerization [Term] id: GO:0031117 name: positive regulation of microtubule depolymerization def: "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "activation of microtubule depolymerization" NARROW [] synonym: "microtubule destabilization" EXACT [] synonym: "positive regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "positive regulation of microtubule disassembly" EXACT [] synonym: "stimulation of microtubule depolymerization" NARROW [] synonym: "up regulation of microtubule depolymerization" EXACT [] synonym: "up-regulation of microtubule depolymerization" EXACT [] synonym: "upregulation of microtubule depolymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901881 ! positive regulation of protein depolymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007019 ! positively regulates microtubule depolymerization relationship: RO:0002213 GO:0007019 ! positively regulates microtubule depolymerization [Term] id: GO:0031122 name: cytoplasmic microtubule organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." [GOC:mah] synonym: "cytoplasmic microtubule organisation" EXACT [] synonym: "cytoplasmic microtubule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005881 ! results in organization of cytoplasmic microtubule relationship: RO:0002592 GO:0005881 ! results in organization of cytoplasmic microtubule [Term] id: GO:0031128 name: developmental induction def: "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment relationship: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment relationship: in_taxon NCBITaxon:131567 ! cellular organisms property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0031175 name: neuron projection development def: "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah] synonym: "neurite biosynthesis" NARROW [] synonym: "neurite development" NARROW [GOC:dph] synonym: "neurite formation" NARROW [] synonym: "neurite growth" NARROW [] synonym: "neurite outgrowth" NARROW [] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: part_of GO:0048666 ! neuron development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048666 ! neuron development [Term] id: GO:0031252 name: cell leading edge def: "The area of a motile cell closest to the direction of movement." [GOC:pg] subset: goslim_pir synonym: "front of cell" EXACT [] synonym: "leading edge of cell" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of CL:0000000 ! cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0031253 name: cell projection membrane def: "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." [GOC:krc, GOC:mah] synonym: "membrane extension" RELATED [] synonym: "membrane projection" RELATED [] is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection relationship: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0031256 name: leading edge membrane def: "The portion of the plasma membrane surrounding the leading edge of a motile cell." [GOC:mah] is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0031252 ! cell leading edge property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0031333 name: negative regulation of protein-containing complex assembly def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "down regulation of protein complex assembly" EXACT [] synonym: "down-regulation of protein complex assembly" EXACT [] synonym: "downregulation of protein complex assembly" EXACT [] synonym: "inhibition of protein complex assembly" NARROW [] synonym: "negative regulation of protein complex assembly" RELATED [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0065003 ! negatively regulates protein-containing complex assembly relationship: RO:0002212 GO:0065003 ! negatively regulates protein-containing complex assembly [Term] id: GO:0031334 name: positive regulation of protein-containing complex assembly def: "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "activation of protein complex assembly" NARROW [] synonym: "positive regulation of protein complex assembly" RELATED [] synonym: "stimulation of protein complex assembly" NARROW [] synonym: "up regulation of protein complex assembly" EXACT [] synonym: "up-regulation of protein complex assembly" EXACT [] synonym: "upregulation of protein complex assembly" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0065003 ! positively regulates protein-containing complex assembly relationship: RO:0002213 GO:0065003 ! positively regulates protein-containing complex assembly [Term] id: GO:0031338 name: regulation of vesicle fusion def: "Any process that modulates the frequency, rate or extent of vesicle fusion." [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0060627 ! regulation of vesicle-mediated transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006906 ! regulates vesicle fusion relationship: RO:0002211 GO:0006906 ! regulates vesicle fusion [Term] id: GO:0031339 name: negative regulation of vesicle fusion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "down regulation of vesicle fusion" EXACT [] synonym: "down-regulation of vesicle fusion" EXACT [] synonym: "downregulation of vesicle fusion" EXACT [] synonym: "inhibition of vesicle fusion" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006906 ! negatively regulates vesicle fusion relationship: RO:0002212 GO:0006906 ! negatively regulates vesicle fusion [Term] id: GO:0031340 name: positive regulation of vesicle fusion def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "activation of vesicle fusion" NARROW [] synonym: "stimulation of vesicle fusion" NARROW [] synonym: "up regulation of vesicle fusion" EXACT [] synonym: "up-regulation of vesicle fusion" EXACT [] synonym: "upregulation of vesicle fusion" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006906 ! positively regulates vesicle fusion relationship: RO:0002213 GO:0006906 ! positively regulates vesicle fusion [Term] id: GO:0031344 name: regulation of cell projection organization def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "regulation of cell projection organisation" EXACT [] synonym: "regulation of cell projection organization and biogenesis" RELATED [GOC:mah] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030030 ! regulates cell projection organization relationship: RO:0002211 GO:0030030 ! regulates cell projection organization [Term] id: GO:0031345 name: negative regulation of cell projection organization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "down regulation of cell projection organization" EXACT [GOC:mah] synonym: "down-regulation of cell projection organization" EXACT [] synonym: "downregulation of cell projection organization" EXACT [] synonym: "inhibition of cell projection organization" NARROW [] synonym: "negative regulation of cell projection organisation" EXACT [] synonym: "negative regulation of cell projection organization and biogenesis" RELATED [GOC:mah] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030030 ! negatively regulates cell projection organization relationship: RO:0002212 GO:0030030 ! negatively regulates cell projection organization [Term] id: GO:0031346 name: positive regulation of cell projection organization def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "activation of cell projection organization" NARROW [] synonym: "positive regulation of cell projection organisation" EXACT [] synonym: "positive regulation of cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cell projection organization" NARROW [] synonym: "up regulation of cell projection organization" EXACT [] synonym: "up-regulation of cell projection organization" EXACT [] synonym: "upregulation of cell projection organization" EXACT [] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030030 ! positively regulates cell projection organization relationship: RO:0002213 GO:0030030 ! positively regulates cell projection organization [Term] id: GO:0031347 name: regulation of defense response def: "Any process that modulates the frequency, rate or extent of a defense response." [GOC:mah] is_a: GO:0080134 ! regulation of response to stress intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006952 ! regulates defense response relationship: RO:0002211 GO:0006952 ! regulates defense response [Term] id: GO:0031348 name: negative regulation of defense response def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah] synonym: "down regulation of defense response" EXACT [] synonym: "down-regulation of defense response" EXACT [] synonym: "downregulation of defense response" EXACT [] synonym: "inhibition of defense response" NARROW [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006952 ! negatively regulates defense response relationship: RO:0002212 GO:0006952 ! negatively regulates defense response [Term] id: GO:0031349 name: positive regulation of defense response def: "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah] synonym: "activation of defense response" NARROW [] synonym: "stimulation of defense response" NARROW [] synonym: "up regulation of defense response" EXACT [] synonym: "up-regulation of defense response" EXACT [] synonym: "upregulation of defense response" EXACT [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006952 ! positively regulates defense response relationship: RO:0002213 GO:0006952 ! positively regulates defense response [Term] id: GO:0031410 name: cytoplasmic vesicle alt_id: GO:0016023 def: "A vesicle found in the cytoplasm of a cell." [GOC:ai, GOC:mah, GOC:vesicles] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_generic subset: goslim_mouse subset: goslim_yeast synonym: "cytoplasmic membrane bounded vesicle" RELATED [] synonym: "cytoplasmic membrane-enclosed vesicle" RELATED [] synonym: "cytoplasmic, membrane-bounded vesicle" RELATED [] xref: NIF_Subcellular:sao180601769 is_a: GO:0097708 ! intracellular vesicle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0031445 name: regulation of heterochromatin formation def: "Any process that modulates the frequency, rate, extent or location of heterochromatin formation." [GOC:mah] synonym: "regulation of heterochromatin assembly" EXACT [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0120261 ! regulation of heterochromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031507 ! regulates heterochromatin formation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0031507 ! regulates heterochromatin formation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23553" xsd:anyURI [Term] id: GO:0031452 name: negative regulation of heterochromatin formation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation." [PMID:16855380] synonym: "chromatin decompaction" EXACT [] synonym: "chromatin decondensation" EXACT [PMID:16855380] synonym: "down regulation of heterochromatin formation" EXACT [] synonym: "down-regulation of heterochromatin formation" EXACT [] synonym: "downregulation of heterochromatin formation" EXACT [] synonym: "inhibition of heterochromatin formation" NARROW [] synonym: "negative regulation of heterochromatin assembly" EXACT [] is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0031445 ! regulation of heterochromatin formation is_a: GO:0120262 ! negative regulation of heterochromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031507 ! negatively regulates heterochromatin formation relationship: RO:0002212 GO:0031507 ! negatively regulates heterochromatin formation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23553" xsd:anyURI [Term] id: GO:0031453 name: positive regulation of heterochromatin formation def: "Any process that activates or increases the frequency, rate or extent of heterochromatin formation." [GOC:mah] synonym: "activation of heterochromatin formation" NARROW [] synonym: "positive regulation of heterochromatin assembly" EXACT [] synonym: "stimulation of heterochromatin formation" NARROW [] synonym: "up regulation of heterochromatin formation" EXACT [] synonym: "up-regulation of heterochromatin formation" EXACT [] synonym: "upregulation of heterochromatin formation" EXACT [] is_a: GO:0031445 ! regulation of heterochromatin formation is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0120263 ! positive regulation of heterochromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0031507 ! positively regulates heterochromatin formation relationship: RO:0002213 GO:0031507 ! positively regulates heterochromatin formation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23553" xsd:anyURI [Term] id: GO:0031503 name: protein-containing complex localization alt_id: GO:0034629 def: "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." [GOC:mah] synonym: "cellular protein complex localisation" RELATED [GOC:mah] synonym: "cellular protein complex localization" RELATED [] synonym: "cellular protein-containing complex localization" RELATED [] synonym: "establishment and maintenance of cellular protein complex localization" RELATED [] synonym: "establishment and maintenance of protein complex localization" EXACT [] synonym: "protein complex localisation" EXACT [GOC:mah] synonym: "protein complex localization" RELATED [] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: RO:0004009 GO:0032991 ! has primary input protein-containing complex relationship: RO:0004009 GO:0032991 ! has primary input protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI [Term] id: GO:0031507 name: heterochromatin formation alt_id: GO:0006342 alt_id: GO:0006343 alt_id: GO:0016440 alt_id: GO:0070869 alt_id: GO:1904497 def: "An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation." [PMID:25192661, PMID:33827924] synonym: "chromatin silencing" EXACT [] synonym: "chromatin-mediated silencing" EXACT [] synonym: "establishment of chromatin silencing" RELATED [] synonym: "establishment of heterochromatic silencing" RELATED [] synonym: "establishment of heterochromatin architecture" EXACT [GOC:mah] synonym: "establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region" NARROW [GOC:TermGenie] synonym: "establishment of heterochromatin architecture involved in chromatin silencing at pericentric region" NARROW [GOC:TermGenie] synonym: "heterochromatic silencing" RELATED [] synonym: "heterochromatin assembly" EXACT [] synonym: "heterochromatin assembly involved in chromatin silencing" RELATED [] synonym: "heterochromatin assembly involved in chromatin silencing at centromere outer repeat region" NARROW [] synonym: "heterochromatin assembly involved in chromatin silencing at pericentric region" NARROW [GOC:TermGenie] synonym: "heterochromatin formation involved in chromatin silencing" RELATED [] synonym: "heterochromatin formation involved in chromatin silencing at centromere outer repeat region" NARROW [GOC:TermGenie] synonym: "heterochromatin formation involved in chromatin silencing at pericentric region" NARROW [GOC:TermGenie] synonym: "heterochromatin maintenance" BROAD [] synonym: "TGS" BROAD [] synonym: "transcriptional gene silencing" RELATED [] xref: Reactome:R-HSA-5334118 "DNA methylation" is_a: GO:0022607 ! cellular component assembly is_a: GO:0045814 ! negative regulation of gene expression, epigenetic is_a: GO:0070828 ! heterochromatin organization intersection_of: GO:0006325 ! chromatin organization intersection_of: RO:0002588 GO:0000792 ! results in assembly of heterochromatin relationship: ends_with GO:0033696 ! heterochromatin boundary formation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002588 GO:0000792 ! results in assembly of heterochromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18954" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19112" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22030" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23553" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26702" xsd:anyURI [Term] id: GO:0031514 name: motile cilium alt_id: GO:0009434 alt_id: GO:0031512 def: "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931] synonym: "microtubule-based flagellum" RELATED [] synonym: "motile cilia" EXACT [] synonym: "motile primary cilia" RELATED [] synonym: "motile primary cilium" RELATED [] synonym: "motile secondary cilium" RELATED [] synonym: "nodal cilium" RELATED [] is_a: GO:0005929 ! cilium intersection_of: GO:0005929 ! cilium intersection_of: capable_of GO:0003341 ! cilium movement relationship: capable_of GO:0003341 ! cilium movement property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0031594 name: neuromuscular junction def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln] comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT. synonym: "motor endplate" RELATED [NIF_Subcellular:nlx_subcell_20090512] synonym: "NMJ" RELATED [GOC:ha] xref: NIF_Subcellular:sao1124888485 xref: Wikipedia:Neuromuscular_junction is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: overlaps CL:0000100 ! motor neuron intersection_of: overlaps CL:0000187 ! muscle cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: overlaps CL:0000100 ! motor neuron relationship: overlaps CL:0000187 ! muscle cell [Term] id: GO:0031641 name: regulation of myelination def: "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042552 ! regulates myelination relationship: RO:0002211 GO:0042552 ! regulates myelination [Term] id: GO:0031642 name: negative regulation of myelination def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] synonym: "down regulation of myelination" EXACT [] synonym: "down-regulation of myelination" EXACT [] synonym: "downregulation of myelination" EXACT [] synonym: "inhibition of myelination" NARROW [] is_a: GO:0031641 ! regulation of myelination is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042552 ! negatively regulates myelination relationship: RO:0002212 GO:0042552 ! negatively regulates myelination [Term] id: GO:0031643 name: positive regulation of myelination def: "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] synonym: "activation of myelination" NARROW [] synonym: "stimulation of myelination" NARROW [] synonym: "up regulation of myelination" EXACT [] synonym: "up-regulation of myelination" EXACT [] synonym: "upregulation of myelination" EXACT [] is_a: GO:0031641 ! regulation of myelination is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042552 ! positively regulates myelination relationship: RO:0002213 GO:0042552 ! positively regulates myelination [Term] id: GO:0031644 name: regulation of nervous system process def: "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "regulation of neurological system process" EXACT [] synonym: "regulation of neurophysiological process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050877 ! regulates nervous system process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0050877 ! regulates nervous system process [Term] id: GO:0031645 name: negative regulation of nervous system process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "down regulation of neurological process" EXACT [] synonym: "down-regulation of neurological process" EXACT [] synonym: "downregulation of neurological process" EXACT [] synonym: "inhibition of neurological process" NARROW [] synonym: "negative regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of neurological system process" EXACT [] synonym: "negative regulation of neurophysiological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050877 ! negatively regulates nervous system process relationship: RO:0002212 GO:0050877 ! negatively regulates nervous system process [Term] id: GO:0031646 name: positive regulation of nervous system process def: "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "activation of neurological process" NARROW [] synonym: "positive regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of neurological system process" EXACT [] synonym: "positive regulation of neurophysiological process" EXACT [] synonym: "stimulation of neurological process" NARROW [] synonym: "up regulation of neurological process" EXACT [] synonym: "up-regulation of neurological process" EXACT [] synonym: "upregulation of neurological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050877 ! positively regulates nervous system process relationship: RO:0002213 GO:0050877 ! positively regulates nervous system process [Term] id: GO:0031965 name: nuclear membrane def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz] xref: NIF_Subcellular:sao1687101204 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005634 ! nucleus relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005635 ! nuclear envelope [Term] id: GO:0031967 name: organelle envelope def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz] subset: goslim_mouse is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043229 ! intracellular organelle [Term] id: GO:0031968 name: organelle outer membrane def: "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." [GOC:mah] is_a: GO:0019867 ! outer membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043226 ! organelle intersection_of: part_of GO:0031967 ! organelle envelope relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0031967 ! organelle envelope [Term] id: GO:0031974 name: membrane-enclosed lumen def: "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." [GOC:add, GOC:mah] is_a: GO:0110165 ! cellular anatomical structure disjoint_from: GO:0045202 ! synapse [Term] id: GO:0031981 name: nuclear lumen def: "The volume enclosed by the nuclear inner membrane." [GOC:mah, GOC:pz] is_a: GO:0070013 ! intracellular organelle lumen relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005634 ! nucleus [Term] id: GO:0031982 name: vesicle alt_id: GO:0031988 def: "Any small, fluid-filled, spherical organelle enclosed by membrane." [GOC:mah, GOC:pz, GOC:vesicles] subset: goslim_pir synonym: "membrane-bounded vesicle" RELATED [] synonym: "membrane-enclosed vesicle" RELATED [] xref: NIF_Subcellular:sao221389602 xref: Wikipedia:Vesicle_(biology) is_a: GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031987 name: locomotion involved in locomotory behavior def: "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:mah] synonym: "locomotion during locomotory behaviour" EXACT [] is_a: GO:0040011 ! locomotion intersection_of: GO:0040011 ! locomotion intersection_of: part_of GO:0007626 ! locomotory behavior relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007626 ! locomotory behavior [Term] id: GO:0032024 name: positive regulation of insulin secretion def: "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah] synonym: "activation of insulin secretion" NARROW [] synonym: "stimulation of insulin secretion" NARROW [] synonym: "up regulation of insulin secretion" EXACT [] synonym: "up-regulation of insulin secretion" EXACT [] synonym: "upregulation of insulin secretion" EXACT [] xref: Reactome:R-HSA-399997 "Acetylcholine regulates insulin secretion" is_a: GO:0050714 ! positive regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030073 ! positively regulates insulin secretion relationship: RO:0002213 GO:0030073 ! positively regulates insulin secretion [Term] id: GO:0032057 name: negative regulation of translational initiation in response to stress def: "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "down regulation of translation initiation in response to stress" EXACT [] synonym: "down-regulation of translation initiation in response to stress" EXACT [] synonym: "downregulation of translation initiation in response to stress" EXACT [] synonym: "inhibition of translation initiation in response to stress" NARROW [] is_a: GO:0045947 ! negative regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: part_of GO:0006950 ! response to stress intersection_of: RO:0002212 GO:0006413 ! negatively regulates translational initiation relationship: part_of GO:0006950 ! response to stress [Term] id: GO:0032058 name: positive regulation of translational initiation in response to stress def: "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "activation of translation initiation in response to stress" NARROW [] synonym: "stimulation of translation initiation in response to stress" NARROW [] synonym: "up regulation of translation initiation in response to stress" EXACT [] synonym: "up-regulation of translation initiation in response to stress" EXACT [] synonym: "upregulation of translation initiation in response to stress" EXACT [] is_a: GO:0045948 ! positive regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: part_of GO:0006950 ! response to stress intersection_of: RO:0002213 GO:0006413 ! positively regulates translational initiation relationship: part_of GO:0006950 ! response to stress [Term] id: GO:0032059 name: bleb def: "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] subset: goslim_pir synonym: "plasma membrane bleb" EXACT [GOC:pr] xref: Wikipedia:Bleb_(cell_biology) is_a: GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0032060 name: bleb assembly def: "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] synonym: "blebbing" BROAD [GOC:pr] synonym: "cell blebbing" EXACT [] synonym: "membrane blebbing" BROAD [GOC:pr] synonym: "plasma membrane bleb assembly" EXACT [GOC:pr] synonym: "plasma membrane blebbing" EXACT [GOC:pr] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0032059 ! results in assembly of bleb relationship: RO:0002588 GO:0032059 ! results in assembly of bleb [Term] id: GO:0032065 name: maintenance of protein location in cell cortex def: "A process in which a protein or protein complex is maintained in a specific location in the cell cortex." [GOC:vw] synonym: "cortical protein anchoring" RELATED [] is_a: GO:0032507 ! maintenance of protein location in cell intersection_of: GO:0045185 ! maintenance of protein location intersection_of: BFO:0000066 GO:0005938 ! occurs in cell cortex relationship: BFO:0000066 GO:0005938 ! occurs in cell cortex [Term] id: GO:0032101 name: regulation of response to external stimulus def: "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009605 ! regulates response to external stimulus relationship: RO:0002211 GO:0009605 ! regulates response to external stimulus [Term] id: GO:0032102 name: negative regulation of response to external stimulus def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "down regulation of response to external stimulus" EXACT [] synonym: "down-regulation of response to external stimulus" EXACT [] synonym: "downregulation of response to external stimulus" EXACT [] synonym: "inhibition of response to external stimulus" NARROW [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009605 ! negatively regulates response to external stimulus relationship: RO:0002212 GO:0009605 ! negatively regulates response to external stimulus [Term] id: GO:0032103 name: positive regulation of response to external stimulus def: "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "activation of response to external stimulus" NARROW [] synonym: "stimulation of response to external stimulus" NARROW [] synonym: "up regulation of response to external stimulus" EXACT [] synonym: "up-regulation of response to external stimulus" EXACT [] synonym: "upregulation of response to external stimulus" EXACT [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009605 ! positively regulates response to external stimulus relationship: RO:0002213 GO:0009605 ! positively regulates response to external stimulus [Term] id: GO:0032127 name: dense core granule membrane def: "The lipid bilayer surrounding a dense core granule." [GOC:mah] synonym: "dense core vesicle membrane" EXACT [GOC:kmv] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0031045 ! dense core granule relationship: bounding_layer_of GO:0031045 ! dense core granule relationship: part_of GO:0031045 ! dense core granule property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0032222 name: regulation of synaptic transmission, cholinergic def: "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007271 ! regulates synaptic transmission, cholinergic relationship: RO:0002211 GO:0007271 ! regulates synaptic transmission, cholinergic [Term] id: GO:0032223 name: negative regulation of synaptic transmission, cholinergic def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "down regulation of synaptic transmission, cholinergic" EXACT [] synonym: "down-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "downregulation of synaptic transmission, cholinergic" EXACT [] synonym: "inhibition of synaptic transmission, cholinergic" NARROW [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050805 ! negative regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007271 ! negatively regulates synaptic transmission, cholinergic relationship: RO:0002212 GO:0007271 ! negatively regulates synaptic transmission, cholinergic [Term] id: GO:0032224 name: positive regulation of synaptic transmission, cholinergic def: "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "activation of synaptic transmission, cholinergic" NARROW [] synonym: "stimulation of synaptic transmission, cholinergic" NARROW [] synonym: "up regulation of synaptic transmission, cholinergic" EXACT [] synonym: "up-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "upregulation of synaptic transmission, cholinergic" EXACT [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050806 ! positive regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007271 ! positively regulates synaptic transmission, cholinergic relationship: RO:0002213 GO:0007271 ! positively regulates synaptic transmission, cholinergic [Term] id: GO:0032231 name: regulation of actin filament bundle assembly def: "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "regulation of actin cable assembly" EXACT [GOC:dph, GOC:tb] synonym: "regulation of actin filament bundle formation" RELATED [GOC:dph] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0110053 ! regulation of actin filament organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051017 ! regulates actin filament bundle assembly relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0051017 ! regulates actin filament bundle assembly [Term] id: GO:0032232 name: negative regulation of actin filament bundle assembly def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "down regulation of actin filament bundle formation" EXACT [] synonym: "down-regulation of actin filament bundle formation" EXACT [] synonym: "downregulation of actin filament bundle formation" EXACT [] synonym: "inhibition of actin filament bundle formation" NARROW [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051017 ! negatively regulates actin filament bundle assembly relationship: RO:0002212 GO:0051017 ! negatively regulates actin filament bundle assembly [Term] id: GO:0032233 name: positive regulation of actin filament bundle assembly def: "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "activation of actin filament bundle formation" NARROW [] synonym: "stimulation of actin filament bundle formation" NARROW [] synonym: "up regulation of actin filament bundle formation" EXACT [] synonym: "up-regulation of actin filament bundle formation" EXACT [] synonym: "upregulation of actin filament bundle formation" EXACT [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051017 ! positively regulates actin filament bundle assembly relationship: RO:0002213 GO:0051017 ! positively regulates actin filament bundle assembly [Term] id: GO:0032239 name: regulation of nucleobase-containing compound transport def: "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015931 ! regulates nucleobase-containing compound transport relationship: RO:0002211 GO:0015931 ! regulates nucleobase-containing compound transport [Term] id: GO:0032240 name: negative regulation of nucleobase-containing compound transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015931 ! negatively regulates nucleobase-containing compound transport relationship: RO:0002212 GO:0015931 ! negatively regulates nucleobase-containing compound transport [Term] id: GO:0032241 name: positive regulation of nucleobase-containing compound transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015931 ! positively regulates nucleobase-containing compound transport relationship: RO:0002213 GO:0015931 ! positively regulates nucleobase-containing compound transport [Term] id: GO:0032252 name: secretory granule localization def: "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] synonym: "secretory granule clustering" RELATED [] synonym: "secretory granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0030141 ! has primary input secretory granule relationship: RO:0004009 GO:0030141 ! has primary input secretory granule [Term] id: GO:0032253 name: dense core granule localization def: "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] synonym: "dense core granule clustering" RELATED [] synonym: "dense core granule localisation" EXACT [GOC:mah] synonym: "dense core vesicle localization" EXACT [GOC:kmv] is_a: GO:0032252 ! secretory granule localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0031045 ! has primary input dense core granule relationship: RO:0004009 GO:0031045 ! has primary input dense core granule [Term] id: GO:0032271 name: regulation of protein polymerization def: "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "regulation of protein polymerisation" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051258 ! regulates protein polymerization relationship: RO:0002211 GO:0051258 ! regulates protein polymerization [Term] id: GO:0032272 name: negative regulation of protein polymerization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "down regulation of protein polymerization" EXACT [] synonym: "down-regulation of protein polymerization" EXACT [] synonym: "downregulation of protein polymerization" EXACT [] synonym: "inhibition of protein polymerization" NARROW [] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051258 ! negatively regulates protein polymerization relationship: RO:0002212 GO:0051258 ! negatively regulates protein polymerization [Term] id: GO:0032273 name: positive regulation of protein polymerization def: "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "activation of protein polymerization" NARROW [] synonym: "stimulation of protein polymerization" NARROW [] synonym: "up regulation of protein polymerization" EXACT [] synonym: "up-regulation of protein polymerization" EXACT [] synonym: "upregulation of protein polymerization" EXACT [] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051258 ! positively regulates protein polymerization relationship: RO:0002213 GO:0051258 ! positively regulates protein polymerization [Term] id: GO:0032288 name: myelin assembly def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system." [GOC:dgh, GOC:dph, GOC:tb] synonym: "myelin formation" RELATED [GOC:dph, GOC:tb] synonym: "myelin sheath assembly" EXACT [] is_a: GO:0010927 ! cellular component assembly involved in morphogenesis intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0043209 ! results in assembly of myelin sheath relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042552 ! myelination relationship: RO:0002588 GO:0043209 ! results in assembly of myelin sheath [Term] id: GO:0032289 name: central nervous system myelin formation def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system." [GOC:dgh] synonym: "central nervous system myelin sheath formation" EXACT [] synonym: "myelin formation in central nervous system" EXACT [] is_a: GO:0032288 ! myelin assembly intersection_of: GO:0032288 ! myelin assembly intersection_of: BFO:0000066 UBERON:0001017 ! occurs in central nervous system relationship: BFO:0000066 UBERON:0001017 ! occurs in central nervous system relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0022010 ! central nervous system myelination [Term] id: GO:0032290 name: peripheral nervous system myelin formation def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system." [GOC:dgh] synonym: "myelin formation in peripheral nervous system" EXACT [] synonym: "peripheral nervous system myelin sheath formation" EXACT [] is_a: GO:0032288 ! myelin assembly intersection_of: GO:0032288 ! myelin assembly intersection_of: BFO:0000066 UBERON:0000010 ! occurs in peripheral nervous system relationship: BFO:0000066 UBERON:0000010 ! occurs in peripheral nervous system relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0022011 ! myelination in peripheral nervous system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19106" xsd:anyURI [Term] id: GO:0032291 name: axon ensheathment in central nervous system def: "The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh] synonym: "ensheathment of axons in central nervous system" EXACT [] is_a: GO:0008366 ! axon ensheathment intersection_of: GO:0008366 ! axon ensheathment intersection_of: BFO:0000066 UBERON:0001017 ! occurs in central nervous system relationship: BFO:0000066 UBERON:0001017 ! occurs in central nervous system relationship: in_taxon NCBITaxon:33213 ! Bilateria [Term] id: GO:0032292 name: peripheral nervous system axon ensheathment def: "The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh] synonym: "ensheathment of axons in peripheral nervous system" EXACT [] is_a: GO:0008366 ! axon ensheathment intersection_of: GO:0008366 ! axon ensheathment intersection_of: BFO:0000066 UBERON:0000010 ! occurs in peripheral nervous system relationship: BFO:0000066 UBERON:0000010 ! occurs in peripheral nervous system [Term] id: GO:0032330 name: regulation of chondrocyte differentiation def: "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002062 ! regulates chondrocyte differentiation relationship: RO:0002211 GO:0002062 ! regulates chondrocyte differentiation [Term] id: GO:0032331 name: negative regulation of chondrocyte differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "down regulation of chondrocyte differentiation" EXACT [] synonym: "down-regulation of chondrocyte differentiation" EXACT [] synonym: "downregulation of chondrocyte differentiation" EXACT [] synonym: "inhibition of chondrocyte differentiation" NARROW [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0061037 ! negative regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002062 ! negatively regulates chondrocyte differentiation relationship: RO:0002212 GO:0002062 ! negatively regulates chondrocyte differentiation [Term] id: GO:0032332 name: positive regulation of chondrocyte differentiation def: "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "activation of chondrocyte differentiation" NARROW [] synonym: "stimulation of chondrocyte differentiation" NARROW [] synonym: "up regulation of chondrocyte differentiation" EXACT [] synonym: "up-regulation of chondrocyte differentiation" EXACT [] synonym: "upregulation of chondrocyte differentiation" EXACT [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0061036 ! positive regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002062 ! positively regulates chondrocyte differentiation relationship: RO:0002213 GO:0002062 ! positively regulates chondrocyte differentiation [Term] id: GO:0032364 name: intracellular oxygen homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell." [GOC:rph] synonym: "cellular oxygen homeostasis" EXACT [] synonym: "oxygen homeostasis" BROAD [] is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis intersection_of: RO:0002332 CHEBI:15379 ! regulates levels of dioxygen relationship: RO:0002332 CHEBI:15379 ! regulates levels of dioxygen property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24224" xsd:anyURI [Term] id: GO:0032365 name: intracellular lipid transport def: "The directed movement of lipids within cells." [GOC:mah] is_a: GO:0006869 ! lipid transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0032368 name: regulation of lipid transport def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006869 ! regulates lipid transport relationship: RO:0002211 GO:0006869 ! regulates lipid transport [Term] id: GO:0032369 name: negative regulation of lipid transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of lipid transport" EXACT [] synonym: "down-regulation of lipid transport" EXACT [] synonym: "downregulation of lipid transport" EXACT [] synonym: "inhibition of lipid transport" NARROW [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051051 ! negative regulation of transport is_a: GO:1905953 ! negative regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006869 ! negatively regulates lipid transport relationship: RO:0002212 GO:0006869 ! negatively regulates lipid transport [Term] id: GO:0032370 name: positive regulation of lipid transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of lipid transport" NARROW [] synonym: "stimulation of lipid transport" NARROW [] synonym: "up regulation of lipid transport" EXACT [] synonym: "up-regulation of lipid transport" EXACT [] synonym: "upregulation of lipid transport" EXACT [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051050 ! positive regulation of transport is_a: GO:1905954 ! positive regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006869 ! positively regulates lipid transport relationship: RO:0002213 GO:0006869 ! positively regulates lipid transport [Term] id: GO:0032377 name: regulation of intracellular lipid transport def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032365 ! regulates intracellular lipid transport relationship: RO:0002211 GO:0032365 ! regulates intracellular lipid transport [Term] id: GO:0032378 name: negative regulation of intracellular lipid transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "down regulation of intracellular lipid transport" EXACT [] synonym: "down-regulation of intracellular lipid transport" EXACT [] synonym: "downregulation of intracellular lipid transport" EXACT [] synonym: "inhibition of intracellular lipid transport" NARROW [] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032387 ! negative regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032365 ! negatively regulates intracellular lipid transport relationship: RO:0002212 GO:0032365 ! negatively regulates intracellular lipid transport [Term] id: GO:0032379 name: positive regulation of intracellular lipid transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "activation of intracellular lipid transport" NARROW [] synonym: "stimulation of intracellular lipid transport" NARROW [] synonym: "up regulation of intracellular lipid transport" EXACT [] synonym: "up-regulation of intracellular lipid transport" EXACT [] synonym: "upregulation of intracellular lipid transport" EXACT [] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032388 ! positive regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032365 ! positively regulates intracellular lipid transport relationship: RO:0002213 GO:0032365 ! positively regulates intracellular lipid transport [Term] id: GO:0032386 name: regulation of intracellular transport def: "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] subset: gocheck_do_not_annotate is_a: GO:0051049 ! regulation of transport is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046907 ! regulates intracellular transport relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0046907 ! regulates intracellular transport [Term] id: GO:0032387 name: negative regulation of intracellular transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "down regulation of intracellular transport" EXACT [] synonym: "down-regulation of intracellular transport" EXACT [] synonym: "downregulation of intracellular transport" EXACT [] synonym: "inhibition of intracellular transport" NARROW [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046907 ! negatively regulates intracellular transport relationship: RO:0002212 GO:0046907 ! negatively regulates intracellular transport [Term] id: GO:0032388 name: positive regulation of intracellular transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "activation of intracellular transport" NARROW [] synonym: "stimulation of intracellular transport" NARROW [] synonym: "up regulation of intracellular transport" EXACT [] synonym: "up-regulation of intracellular transport" EXACT [] synonym: "upregulation of intracellular transport" EXACT [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046907 ! positively regulates intracellular transport relationship: RO:0002213 GO:0046907 ! positively regulates intracellular transport [Term] id: GO:0032410 name: negative regulation of transporter activity def: "Any process that stops or reduces the activity of a transporter." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of transporter activity" EXACT [] synonym: "down-regulation of transporter activity" EXACT [] synonym: "downregulation of transporter activity" EXACT [] synonym: "inhibition of transporter activity" NARROW [] is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005215 ! negatively regulates transporter activity relationship: RO:0002212 GO:0005215 ! negatively regulates transporter activity [Term] id: GO:0032411 name: positive regulation of transporter activity def: "Any process that activates or increases the activity of a transporter." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of transporter activity" NARROW [] synonym: "stimulation of transporter activity" NARROW [] synonym: "up regulation of transporter activity" EXACT [] synonym: "up-regulation of transporter activity" EXACT [] synonym: "upregulation of transporter activity" EXACT [] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005215 ! positively regulates transporter activity relationship: RO:0002213 GO:0005215 ! positively regulates transporter activity [Term] id: GO:0032413 name: negative regulation of ion transmembrane transporter activity def: "Any process that stops or reduces the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "down regulation of ion transporter activity" EXACT [] synonym: "down-regulation of ion transporter activity" EXACT [] synonym: "downregulation of ion transporter activity" EXACT [] synonym: "inhibition of ion transporter activity" NARROW [] synonym: "negative regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015075 ! negatively regulates monoatomic ion transmembrane transporter activity relationship: RO:0002212 GO:0015075 ! negatively regulates monoatomic ion transmembrane transporter activity [Term] id: GO:0032414 name: positive regulation of ion transmembrane transporter activity def: "Any process that activates or increases the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "activation of ion transporter activity" NARROW [] synonym: "positive regulation of ion transporter activity" EXACT [GOC:tb] synonym: "stimulation of ion transporter activity" NARROW [] synonym: "up regulation of ion transporter activity" EXACT [] synonym: "up-regulation of ion transporter activity" EXACT [] synonym: "upregulation of ion transporter activity" EXACT [] is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015075 ! positively regulates monoatomic ion transmembrane transporter activity relationship: RO:0002213 GO:0015075 ! positively regulates monoatomic ion transmembrane transporter activity [Term] id: GO:0032432 name: actin filament bundle alt_id: GO:0000141 alt_id: GO:0030482 def: "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah] synonym: "actin cable" RELATED [GOC:mah] is_a: GO:0110165 ! cellular anatomical structure relationship: has_part GO:0005884 ! actin filament relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0032501 name: multicellular organismal process namespace: biological_process alt_id: GO:0044707 alt_id: GO:0050874 def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "organismal physiological process" EXACT [] synonym: "single-multicellular organism process" RELATED [] is_a: GO:0008150 ! biological process disjoint_from: GO:0044848 ! biological phase property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2012-09-19T16:07:47Z [Term] id: GO:0032502 name: developmental process namespace: biological_process alt_id: GO:0044767 def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_pir synonym: "development" NARROW [] synonym: "single-organism developmental process" RELATED [] is_a: GO:0008150 ! biological process disjoint_from: GO:0044848 ! biological phase created_by: jl creation_date: 2012-12-19T12:21:31Z [Term] id: GO:0032507 name: maintenance of protein location in cell def: "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." [GOC:isa_complete, GOC:mah] synonym: "maintenance of protein localization in cell" RELATED [GOC:dph, GOC:tb] is_a: GO:0045185 ! maintenance of protein location is_a: GO:0051651 ! maintenance of location in cell intersection_of: GO:0045185 ! maintenance of protein location intersection_of: BFO:0000066 CL:0000000 ! occurs in cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0032528 name: microvillus organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah] synonym: "microvillus organisation" EXACT [GOC:mah] synonym: "microvillus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005902 ! results in organization of microvillus relationship: RO:0002592 GO:0005902 ! results in organization of microvillus property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0032530 name: regulation of microvillus organization def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah] synonym: "regulation of microvillus organisation" EXACT [GOC:mah] synonym: "regulation of microvillus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032528 ! regulates microvillus organization relationship: RO:0002211 GO:0032528 ! regulates microvillus organization property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0032534 name: regulation of microvillus assembly def: "A process that modulates the formation of a microvillus." [GOC:mah] synonym: "regulation of microvillus biogenesis" RELATED [GOC:mah] is_a: GO:0032530 ! regulation of microvillus organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030033 ! regulates microvillus assembly relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0030033 ! regulates microvillus assembly [Term] id: GO:0032535 name: regulation of cellular component size def: "A process that modulates the size of a cellular component." [GOC:mah] is_a: GO:0016043 ! cellular component organization is_a: GO:0090066 ! regulation of anatomical structure size [Term] id: GO:0032589 name: neuron projection membrane def: "The portion of the plasma membrane surrounding a neuron projection." [GOC:mah] is_a: GO:0031253 ! cell projection membrane is_a: GO:0031256 ! leading edge membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043005 ! neuron projection relationship: bounding_layer_of GO:0043005 ! neuron projection relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0043005 ! neuron projection [Term] id: GO:0032594 name: protein transport within lipid bilayer def: "The directed movement of a protein from one location to another within a lipid bilayer." [GOC:mah] synonym: "protein translocation within membrane" EXACT [] synonym: "receptor translocation within membrane" NARROW [] synonym: "receptor transport within lipid bilayer" NARROW [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0061024 ! membrane organization intersection_of: GO:0015031 ! protein transport intersection_of: BFO:0000066 GO:0016020 ! occurs in membrane relationship: BFO:0000066 GO:0016020 ! occurs in membrane [Term] id: GO:0032774 name: RNA biosynthetic process alt_id: GO:0062103 def: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH] comment: Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study. subset: gocheck_do_not_annotate synonym: "double-stranded RNA biosynthesis" NARROW [] synonym: "double-stranded RNA biosynthetic process" NARROW [] synonym: "dsRNA biosynthesis" NARROW [] synonym: "dsRNA biosynthetic process" NARROW [GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:rl] synonym: "RNA anabolism" EXACT [] synonym: "RNA biosynthesis" EXACT [] synonym: "RNA formation" EXACT [] synonym: "RNA synthesis" EXACT [] is_a: GO:0016070 ! RNA metabolic process is_a: GO:0141187 ! nucleic acid biosynthetic process intersection_of: GO:0009059 ! macromolecule biosynthetic process intersection_of: RO:0004008 CHEBI:33697 ! has primary output ribonucleic acid relationship: RO:0004008 CHEBI:33697 ! has primary output ribonucleic acid [Term] id: GO:0032782 name: bile acid secretion def: "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd] is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0046717 ! acid secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:36235 ! has primary input bile acid anion relationship: RO:0004009 CHEBI:36235 ! has primary input bile acid anion [Term] id: GO:0032787 name: monocarboxylic acid metabolic process def: "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:vk] subset: goslim_yeast synonym: "monocarboxylate metabolic process" EXACT [] synonym: "monocarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35757 ! has primary input or output monocarboxylic acid anion relationship: RO:0004007 CHEBI:35757 ! has primary input or output monocarboxylic acid anion [Term] id: GO:0032790 name: ribosome disassembly def: "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." [GOC:mah, GOC:vk] synonym: "ribosome dissociation factor" RELATED [] synonym: "ribosome recycling" NARROW [GOC:db, PMID:9463391] is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005840 ! results in disassembly of ribosome relationship: RO:0002590 GO:0005840 ! results in disassembly of ribosome [Term] id: GO:0032838 name: plasma membrane bounded cell projection cytoplasm def: "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." [GOC:krc, GOC:mah] is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0120025 ! plasma membrane bounded cell projection relationship: part_of GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0032868 name: response to insulin def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732] synonym: "response to insulin stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0042221 ! response to chemical intersection_of: RO:0004009 PR:000009054 ! has primary input preproinsulin relationship: RO:0004009 PR:000009054 ! has primary input preproinsulin property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0032869 name: cellular response to insulin stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732] is_a: GO:0032868 ! response to insulin is_a: GO:0071375 ! cellular response to peptide hormone stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 PR:000009054 ! has primary input preproinsulin property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0032870 name: cellular response to hormone stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:mah] is_a: GO:0009725 ! response to hormone is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:0071495 ! cellular response to endogenous stimulus property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0032871 name: regulation of karyogamy def: "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah] is_a: GO:1903353 ! regulation of nucleus organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000741 ! regulates karyogamy relationship: RO:0002211 GO:0000741 ! regulates karyogamy [Term] id: GO:0032878 name: regulation of establishment or maintenance of cell polarity def: "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007163 ! regulates establishment or maintenance of cell polarity relationship: RO:0002211 GO:0007163 ! regulates establishment or maintenance of cell polarity [Term] id: GO:0032879 name: regulation of localization def: "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah] subset: gocheck_do_not_annotate synonym: "regulation of localisation" EXACT [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051179 ! regulates localization relationship: RO:0002211 GO:0051179 ! regulates localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0032880 name: regulation of protein localization alt_id: GO:1903827 def: "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb] subset: goslim_chembl synonym: "regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein localization" EXACT [] synonym: "regulation of protein localisation" EXACT [GOC:mah] is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008104 ! regulates intracellular protein localization relationship: RO:0002211 GO:0008104 ! regulates intracellular protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:14Z [Term] id: GO:0032881 name: regulation of polysaccharide metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." [GOC:mah] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005976 ! regulates polysaccharide metabolic process relationship: RO:0002211 GO:0005976 ! regulates polysaccharide metabolic process [Term] id: GO:0032885 name: regulation of polysaccharide biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." [GOC:mah] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000271 ! regulates polysaccharide biosynthetic process relationship: RO:0002211 GO:0000271 ! regulates polysaccharide biosynthetic process [Term] id: GO:0032886 name: regulation of microtubule-based process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007017 ! regulates microtubule-based process relationship: RO:0002211 GO:0007017 ! regulates microtubule-based process [Term] id: GO:0032890 name: regulation of organic acid transport def: "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015849 ! regulates organic acid transport relationship: RO:0002211 GO:0015849 ! regulates organic acid transport [Term] id: GO:0032891 name: negative regulation of organic acid transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of organic acid transport" EXACT [] synonym: "down-regulation of organic acid transport" EXACT [] synonym: "downregulation of organic acid transport" EXACT [] synonym: "inhibition of organic acid transport" NARROW [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015849 ! negatively regulates organic acid transport relationship: RO:0002212 GO:0015849 ! negatively regulates organic acid transport [Term] id: GO:0032892 name: positive regulation of organic acid transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of organic acid transport" NARROW [] synonym: "stimulation of organic acid transport" NARROW [] synonym: "up regulation of organic acid transport" EXACT [] synonym: "up-regulation of organic acid transport" EXACT [] synonym: "upregulation of organic acid transport" EXACT [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015849 ! positively regulates organic acid transport relationship: RO:0002213 GO:0015849 ! positively regulates organic acid transport [Term] id: GO:0032940 name: secretion by cell def: "The controlled release of a substance by a cell." [GOC:mah] synonym: "cellular secretion" EXACT [] xref: Wikipedia:Secretion is_a: GO:0046903 ! secretion is_a: GO:0140352 ! export from cell [Term] id: GO:0032941 name: secretion by tissue namespace: biological_process def: "The controlled release of a substance by a tissue." [GOC:mah] synonym: "expulsion of gland contents" RELATED [GOC:mah] synonym: "tissue secretion" EXACT [] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0046903 ! secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0032943 name: mononuclear cell proliferation def: "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] synonym: "PBMC proliferation" NARROW [] synonym: "peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0070661 ! leukocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000842 ! acts on population of mononuclear leukocyte relationship: RO:0012003 CL:0000842 ! acts on population of mononuclear leukocyte [Term] id: GO:0032944 name: regulation of mononuclear cell proliferation def: "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "regulation of PBMC proliferation" NARROW [] synonym: "regulation of peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032943 ! regulates mononuclear cell proliferation relationship: RO:0002211 GO:0032943 ! regulates mononuclear cell proliferation [Term] id: GO:0032945 name: negative regulation of mononuclear cell proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "negative regulation of PBMC proliferation" NARROW [] synonym: "negative regulation of peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070664 ! negative regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032943 ! negatively regulates mononuclear cell proliferation relationship: RO:0002212 GO:0032943 ! negatively regulates mononuclear cell proliferation [Term] id: GO:0032946 name: positive regulation of mononuclear cell proliferation def: "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "activation of mononuclear cell proliferation" NARROW [] synonym: "positive regulation of PBMC proliferation" NARROW [] synonym: "positive regulation of peripheral blood mononuclear cell proliferation" NARROW [] synonym: "stimulation of mononuclear cell proliferation" NARROW [] synonym: "up regulation of mononuclear cell proliferation" EXACT [] synonym: "up-regulation of mononuclear cell proliferation" EXACT [] synonym: "upregulation of mononuclear cell proliferation" EXACT [] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070665 ! positive regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032943 ! positively regulates mononuclear cell proliferation relationship: RO:0002213 GO:0032943 ! positively regulates mononuclear cell proliferation [Term] id: GO:0032956 name: regulation of actin cytoskeleton organization def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah] synonym: "regulation of actin cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0032970 ! regulation of actin filament-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030036 ! regulates actin cytoskeleton organization relationship: RO:0002211 GO:0030036 ! regulates actin cytoskeleton organization [Term] id: GO:0032963 name: collagen metabolic process def: "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 GO:0005581 ! has primary input or output collagen trimer relationship: RO:0004007 GO:0005581 ! has primary input or output collagen trimer [Term] id: GO:0032964 name: collagen biosynthetic process def: "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen anabolism" EXACT [] synonym: "collagen biosynthesis" EXACT [] synonym: "collagen formation" EXACT [] synonym: "collagen synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 GO:0005581 ! has primary output collagen trimer relationship: RO:0004008 GO:0005581 ! has primary output collagen trimer [Term] id: GO:0032965 name: regulation of collagen biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "regulation of collagen anabolism" EXACT [] synonym: "regulation of collagen biosynthesis" EXACT [] synonym: "regulation of collagen formation" EXACT [] synonym: "regulation of collagen synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032964 ! regulates collagen biosynthetic process relationship: RO:0002211 GO:0032964 ! regulates collagen biosynthetic process [Term] id: GO:0032966 name: negative regulation of collagen biosynthetic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "negative regulation of collagen anabolism" EXACT [] synonym: "negative regulation of collagen biosynthesis" EXACT [] synonym: "negative regulation of collagen formation" EXACT [] synonym: "negative regulation of collagen synthesis" EXACT [] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0010713 ! negative regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032964 ! negatively regulates collagen biosynthetic process relationship: RO:0002212 GO:0032964 ! negatively regulates collagen biosynthetic process [Term] id: GO:0032967 name: positive regulation of collagen biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "positive regulation of collagen anabolism" EXACT [] synonym: "positive regulation of collagen biosynthesis" EXACT [] synonym: "positive regulation of collagen formation" EXACT [] synonym: "positive regulation of collagen synthesis" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0010714 ! positive regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032964 ! positively regulates collagen biosynthetic process relationship: RO:0002213 GO:0032964 ! positively regulates collagen biosynthetic process [Term] id: GO:0032970 name: regulation of actin filament-based process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030029 ! regulates actin filament-based process relationship: RO:0002211 GO:0030029 ! regulates actin filament-based process [Term] id: GO:0032973 name: amino acid export across plasma membrane alt_id: GO:0044746 def: "The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:jl] synonym: "amino acid efflux" EXACT [] synonym: "amino acid export" BROAD [] synonym: "amino acid transmembrane export" BROAD [] is_a: GO:0003333 ! amino acid transmembrane transport is_a: GO:0140115 ! export across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion created_by: jl creation_date: 2012-11-14T14:27:40Z [Term] id: GO:0032974 name: amino acid transmembrane export from vacuole def: "The directed movement of amino acids out of the vacuole, across the vacuolar membrane." [GOC:mah] synonym: "amino acid efflux from vacuole" EXACT [] synonym: "vacuolar amino acid export" EXACT [] is_a: GO:0003333 ! amino acid transmembrane transport is_a: GO:0034486 ! vacuolar transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0002338 GO:0005775 ! has target start location vacuolar lumen intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion relationship: RO:0002338 GO:0005775 ! has target start location vacuolar lumen relationship: RO:0002339 GO:0005829 ! has target end location cytosol [Term] id: GO:0032975 name: amino acid transmembrane import into vacuole def: "The directed movement of amino acids into the vacuole across the vacuolar membrane." [GOC:mah] synonym: "vacuolar amino acid import" EXACT [] is_a: GO:0003333 ! amino acid transmembrane transport is_a: GO:0034486 ! vacuolar transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0005775 ! has target end location vacuolar lumen intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion relationship: RO:0002338 GO:0005829 ! has target start location cytosol relationship: RO:0002339 GO:0005775 ! has target end location vacuolar lumen [Term] id: GO:0032984 name: protein-containing complex disassembly alt_id: GO:0034623 alt_id: GO:0043241 alt_id: GO:0043624 def: "The disaggregation of a protein-containing macromolecular complex into its constituent components." [GOC:mah] synonym: "cellular macromolecule complex disassembly" RELATED [] synonym: "cellular protein complex disassembly" RELATED [] synonym: "macromolecule complex disassembly" RELATED [] synonym: "protein complex disassembly" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0032991 ! results in disassembly of protein-containing complex relationship: RO:0002590 GO:0032991 ! results in disassembly of protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI [Term] id: GO:0032988 name: protein-RNA complex disassembly def: "The disaggregation of a protein-RNA complex into its constituent components." [GOC:mah] synonym: "ribonucleoprotein complex disassembly" EXACT [] synonym: "RNA-protein complex disassembly" EXACT [] synonym: "RNP complex disassembly" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:1990904 ! results in disassembly of ribonucleoprotein complex relationship: RO:0002590 GO:1990904 ! results in disassembly of ribonucleoprotein complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI [Term] id: GO:0032989 name: cellular anatomical entity morphogenesis def: "The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system." [GOC:dph, GOC:mah, GOC:tb] subset: goslim_pir synonym: "cellular component morphogenesis" EXACT [] synonym: "cellular structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0016043 ! cellular component organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25496" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26249" xsd:anyURI [Term] id: GO:0032991 name: protein-containing complex alt_id: GO:0043234 def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah] comment: A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole. subset: goslim_agr subset: goslim_chembl subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "macromolecular complex" EXACT [] synonym: "macromolecule complex" EXACT [] synonym: "protein complex" NARROW [] synonym: "protein containing complex" EXACT [] synonym: "protein-protein complex" NARROW [] is_a: COB:0000080 ! complex of molecules is_a: GO:0005575 ! cellular_component disjoint_from: GO:0110165 ! cellular anatomical structure relationship: has_part PR:000000001 ! protein property_value: editor_note "This is not covalently bonded, which conflicts with changes to the parent definition." xsd:string property_value: IAO:0000111 "protein-containing complex" xsd:string property_value: IAO:0000112 "A ribosome is a protein complex." xsd:string property_value: IAO:0000118 "protein complex" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0033002 name: muscle cell proliferation def: "The expansion of a muscle cell population by cell division." [CL:0000187, GOC:mah] synonym: "myocyte proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000187 ! acts on population of muscle cell relationship: RO:0012003 CL:0000187 ! acts on population of muscle cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0033013 name: tetrapyrrole metabolic process def: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] subset: goslim_pombe subset: goslim_prokaryote synonym: "tetrapyrrole metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:26932 ! has primary input or output tetrapyrrole relationship: RO:0004007 CHEBI:26932 ! has primary input or output tetrapyrrole [Term] id: GO:0033014 name: tetrapyrrole biosynthetic process def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole anabolism" EXACT [] synonym: "tetrapyrrole biosynthesis" EXACT [] synonym: "tetrapyrrole formation" EXACT [] synonym: "tetrapyrrole synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0033013 ! tetrapyrrole metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:26932 ! has primary output tetrapyrrole relationship: RO:0004008 CHEBI:26932 ! has primary output tetrapyrrole [Term] id: GO:0033015 name: tetrapyrrole catabolic process def: "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole breakdown" EXACT [] synonym: "tetrapyrrole catabolism" EXACT [] synonym: "tetrapyrrole degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0033013 ! tetrapyrrole metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:26932 ! has primary input tetrapyrrole relationship: RO:0004009 CHEBI:26932 ! has primary input tetrapyrrole [Term] id: GO:0033028 name: myeloid cell apoptotic process def: "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:15330259, PMID:17133093] synonym: "apoptosis of myeloid cells" EXACT [] synonym: "myeloid cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000763 ! occurs in myeloid cell relationship: BFO:0000066 CL:0000763 ! occurs in myeloid cell property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0033032 name: regulation of myeloid cell apoptotic process def: "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "regulation of myeloid cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033028 ! regulates myeloid cell apoptotic process relationship: RO:0002211 GO:0033028 ! regulates myeloid cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0033033 name: negative regulation of myeloid cell apoptotic process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "down regulation of myeloid cell apoptosis" EXACT [] synonym: "down-regulation of myeloid cell apoptosis" EXACT [] synonym: "downregulation of myeloid cell apoptosis" EXACT [] synonym: "inhibition of myeloid cell apoptosis" NARROW [] synonym: "negative regulation of myeloid cell apoptosis" NARROW [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033028 ! negatively regulates myeloid cell apoptotic process relationship: RO:0002212 GO:0033028 ! negatively regulates myeloid cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0033034 name: positive regulation of myeloid cell apoptotic process def: "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "activation of myeloid cell apoptosis" NARROW [] synonym: "positive regulation of myeloid cell apoptosis" NARROW [] synonym: "stimulation of myeloid cell apoptosis" NARROW [] synonym: "up regulation of myeloid cell apoptosis" EXACT [] synonym: "up-regulation of myeloid cell apoptosis" EXACT [] synonym: "upregulation of myeloid cell apoptosis" EXACT [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033028 ! positively regulates myeloid cell apoptotic process relationship: RO:0002213 GO:0033028 ! positively regulates myeloid cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0033036 name: macromolecule localization def: "Any process in which a macromolecule is transported to, or maintained in, a specific location." [GOC:mah] subset: gocheck_do_not_annotate subset: goslim_flybase_ribbon synonym: "macromolecule localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization [Term] id: GO:0033037 name: polysaccharide localization def: "Any process in which a polysaccharide is transported to, or maintained in, a specific location." [GOC:mah] synonym: "polysaccharide localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: RO:0004009 CHEBI:18154 ! has primary input polysaccharide relationship: RO:0004009 CHEBI:18154 ! has primary input polysaccharide [Term] id: GO:0033043 name: regulation of organelle organization def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah] subset: gocheck_do_not_annotate subset: goslim_yeast synonym: "regulation of organelle organisation" EXACT [GOC:mah] synonym: "regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006996 ! regulates organelle organization relationship: RO:0002211 GO:0006996 ! regulates organelle organization [Term] id: GO:0033044 name: regulation of chromosome organization def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." [GOC:mah] synonym: "regulation of chromosome organisation" EXACT [GOC:mah] synonym: "regulation of chromosome organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051276 ! regulates chromosome organization relationship: RO:0002211 GO:0051276 ! regulates chromosome organization [Term] id: GO:0033045 name: regulation of sister chromatid segregation def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033044 ! regulation of chromosome organization is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000819 ! regulates sister chromatid segregation relationship: RO:0002211 GO:0000819 ! regulates sister chromatid segregation [Term] id: GO:0033046 name: negative regulation of sister chromatid segregation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation is_a: GO:0051985 ! negative regulation of chromosome segregation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000819 ! negatively regulates sister chromatid segregation relationship: RO:0002212 GO:0000819 ! negatively regulates sister chromatid segregation [Term] id: GO:0033047 name: regulation of mitotic sister chromatid segregation def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000070 ! regulates mitotic sister chromatid segregation relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0000070 ! regulates mitotic sister chromatid segregation [Term] id: GO:0033048 name: negative regulation of mitotic sister chromatid segregation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033046 ! negative regulation of sister chromatid segregation is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000070 ! negatively regulates mitotic sister chromatid segregation relationship: RO:0002212 GO:0000070 ! negatively regulates mitotic sister chromatid segregation [Term] id: GO:0033059 name: cellular pigmentation def: "The deposition or aggregation of coloring matter in a cell." [GOC:mtg_MIT_16mar07] is_a: GO:0009987 ! cellular process is_a: GO:0043473 ! pigmentation [Term] id: GO:0033157 name: regulation of intracellular protein transport def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." [GOC:mah] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0051223 ! regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006886 ! regulates intracellular protein transport relationship: RO:0002211 GO:0006886 ! regulates intracellular protein transport [Term] id: GO:0033238 name: regulation of amine metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." [GOC:mah] synonym: "regulation of amine metabolism" EXACT [] synonym: "regulation of cellular amine metabolic process" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009308 ! regulates amine metabolic process relationship: RO:0002211 GO:0009308 ! regulates amine metabolic process [Term] id: GO:0033239 name: negative regulation of amine metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "negative regulation of amine metabolism" EXACT [] synonym: "negative regulation of cellular amine metabolic process" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0033238 ! regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009308 ! negatively regulates amine metabolic process relationship: RO:0002212 GO:0009308 ! negatively regulates amine metabolic process [Term] id: GO:0033240 name: positive regulation of amine metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "positive regulation of amine metabolism" EXACT [] synonym: "positive regulation of cellular amine metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0033238 ! regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009308 ! positively regulates amine metabolic process relationship: RO:0002213 GO:0009308 ! positively regulates amine metabolic process [Term] id: GO:0033241 name: regulation of amine catabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "regulation of amine breakdown" EXACT [] synonym: "regulation of amine catabolism" EXACT [] synonym: "regulation of amine degradation" EXACT [] synonym: "regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0033238 ! regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009310 ! regulates amine catabolic process relationship: RO:0002211 GO:0009310 ! regulates amine catabolic process [Term] id: GO:0033242 name: negative regulation of amine catabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "negative regulation of amine breakdown" EXACT [] synonym: "negative regulation of amine catabolism" EXACT [] synonym: "negative regulation of amine degradation" EXACT [] synonym: "negative regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009310 ! negatively regulates amine catabolic process relationship: RO:0002212 GO:0009310 ! negatively regulates amine catabolic process [Term] id: GO:0033243 name: positive regulation of amine catabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "positive regulation of amine breakdown" EXACT [] synonym: "positive regulation of amine catabolism" EXACT [] synonym: "positive regulation of amine degradation" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009310 ! positively regulates amine catabolic process relationship: RO:0002213 GO:0009310 ! positively regulates amine catabolic process [Term] id: GO:0033278 name: cell proliferation in midbrain def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." [GO_REF:0000021, GOC:dgf] synonym: "cell proliferation in mesencephalon" EXACT [] synonym: "mesencepahalic cell proliferation" RELATED [] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: BFO:0000066 UBERON:0001891 ! occurs in midbrain relationship: BFO:0000066 UBERON:0001891 ! occurs in midbrain relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030901 ! midbrain development [Term] id: GO:0033363 name: secretory granule organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "secretory granule organisation" EXACT [GOC:mah] synonym: "secretory granule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030141 ! results in organization of secretory granule relationship: part_of GO:0010256 ! endomembrane system organization relationship: RO:0002592 GO:0030141 ! results in organization of secretory granule [Term] id: GO:0033365 name: protein localization to organelle def: "A process in which a protein is transported to, or maintained in, a location within an organelle." [GOC:mah] subset: gocheck_do_not_annotate synonym: "protein localisation to organelle" EXACT [GOC:mah] synonym: "protein localization in organelle" EXACT [GOC:mah] is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0043226 ! has target end location organelle relationship: RO:0002339 GO:0043226 ! has target end location organelle [Term] id: GO:0033366 name: protein localization to secretory granule def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule." [GOC:mah] synonym: "protein localisation in secretory granule" EXACT [GOC:mah] synonym: "protein localization in secretory granule" EXACT [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0030141 ! has target end location secretory granule relationship: RO:0002339 GO:0030141 ! has target end location secretory granule [Term] id: GO:0033371 name: T cell secretory granule organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "T cell secretory granule organisation" EXACT [GOC:mah] synonym: "T cell secretory granule organization and biogenesis" RELATED [GOC:mah] synonym: "T lymphocyte secretory granule organization" EXACT [] synonym: "T-cell secretory granule organization" EXACT [] synonym: "T-lymphocyte secretory granule maturation" RELATED [] synonym: "T-lymphocyte secretory granule organization" EXACT [] is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell intersection_of: RO:0002592 GO:0030141 ! results in organization of secretory granule relationship: BFO:0000066 CL:0000084 ! occurs in T cell [Term] id: GO:0033500 name: carbohydrate homeostasis def: "A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell." [GOC:mah] is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:16646 ! regulates levels of carbohydrate relationship: RO:0002332 CHEBI:16646 ! regulates levels of carbohydrate [Term] id: GO:0033604 name: negative regulation of catecholamine secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "down regulation of catecholamine secretion" EXACT [] synonym: "down-regulation of catecholamine secretion" EXACT [] synonym: "downregulation of catecholamine secretion" EXACT [] synonym: "inhibition of catecholamine secretion" NARROW [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050432 ! negatively regulates catecholamine secretion relationship: RO:0002212 GO:0050432 ! negatively regulates catecholamine secretion [Term] id: GO:0033605 name: positive regulation of catecholamine secretion def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "activation of catecholamine secretion" NARROW [] synonym: "stimulation of catecholamine secretion" NARROW [] synonym: "up regulation of catecholamine secretion" EXACT [] synonym: "up-regulation of catecholamine secretion" EXACT [] synonym: "upregulation of catecholamine secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050432 ! positively regulates catecholamine secretion relationship: RO:0002213 GO:0050432 ! positively regulates catecholamine secretion [Term] id: GO:0033696 name: heterochromatin boundary formation alt_id: GO:0031454 def: "A process that forms a boundary that limits the spreading of heterochromatin along a chromosome." [GOC:mah] synonym: "maintenance of heterochromatin boundaries" RELATED [] synonym: "negative regulation of extent of heterochromatin assembly" RELATED [] synonym: "negative regulation of extent of heterochromatin formation" RELATED [] synonym: "negative regulation of heterochromatin spreading" RELATED [] synonym: "regulation of extent of heterochromatin assembly" RELATED [] synonym: "regulation of extent of heterochromatin formation" EXACT [] synonym: "regulation of heterochromatin spreading" RELATED [] is_a: GO:0070828 ! heterochromatin organization relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0031507 ! heterochromatin formation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22028" xsd:anyURI [Term] id: GO:0033750 name: ribosome localization alt_id: GO:0033753 def: "A process in which a ribosome is transported to, and/or maintained in, a specific location." [GOC:mah] synonym: "establishment of ribosome localisation" RELATED [] synonym: "establishment of ribosome localization" RELATED [] synonym: "ribosome localisation" RELATED [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005840 ! has primary input ribosome relationship: RO:0004009 GO:0005840 ! has primary input ribosome [Term] id: GO:0033762 name: response to glucagon def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:sl] synonym: "response to glucagon stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:5391 ! has primary input glucagon relationship: RO:0004009 CHEBI:5391 ! has primary input glucagon property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0033993 name: response to lipid def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:sl] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0004009 CHEBI:18059 ! has primary input lipid [Term] id: GO:0034067 name: protein localization to Golgi apparatus alt_id: GO:0000042 alt_id: GO:0072600 def: "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." [GOC:mah] synonym: "establishment of protein localisation to Golgi" NARROW [GOC:mah] synonym: "establishment of protein localization in Golgi" NARROW [] synonym: "establishment of protein localization to Golgi" NARROW [] synonym: "establishment of protein localization to Golgi apparatus" NARROW [GOC:mah] synonym: "protein localisation in Golgi apparatus" EXACT [GOC:mah] synonym: "protein localization in Golgi apparatus" EXACT [] synonym: "protein targeting to Golgi" RELATED [] synonym: "protein-Golgi targeting" RELATED [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005794 ! has target end location Golgi apparatus relationship: RO:0002339 GO:0005794 ! has target end location Golgi apparatus created_by: mah creation_date: 2011-02-14T02:26:36Z [Term] id: GO:0034101 name: erythrocyte homeostasis def: "Any process of regulating the production and elimination of erythrocytes within an organism." [GOC:add, PMID:10694114, PMID:14754397] synonym: "RBC homeostasis" EXACT [CL:0000232] synonym: "red blood cell homeostasis" EXACT [CL:0000232] is_a: GO:0002262 ! myeloid cell homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000232 ! acts on population of erythrocyte relationship: RO:0012003 CL:0000232 ! acts on population of erythrocyte property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0034219 name: carbohydrate transmembrane transport def: "The process in which a carbohydrate is transported across a membrane." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "carbohydrate membrane transport" EXACT [] synonym: "transmembrane carbohydrate transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0008643 ! carbohydrate transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate [Term] id: GO:0034220 name: monoatomic ion transmembrane transport alt_id: GO:0099131 def: "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "ATP hydrolysis coupled ion transmembrane transport" NARROW [] synonym: "ion membrane transport" EXACT [] synonym: "ion transmembrane transport" BROAD [] synonym: "transmembrane ion transport" EXACT [GOC:dph, GOC:tb] xref: Reactome:R-HSA-983712 "Ion channel transport" is_a: GO:0006811 ! monoatomic ion transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:24867 ! has primary input monoatomic ion [Term] id: GO:0034242 name: negative regulation of syncytium formation by plasma membrane fusion def: "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mah] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000768 ! negatively regulates syncytium formation by plasma membrane fusion relationship: RO:0002212 GO:0000768 ! negatively regulates syncytium formation by plasma membrane fusion [Term] id: GO:0034248 name: regulation of amide metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "regulation of amide metabolism" EXACT [] synonym: "regulation of cellular amide metabolic process" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043603 ! regulates amide metabolic process relationship: RO:0002211 GO:0043603 ! regulates amide metabolic process [Term] id: GO:0034249 name: negative regulation of amide metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "negative regulation of amide metabolism" EXACT [] synonym: "negative regulation of cellular amide metabolic process" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0034248 ! regulation of amide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043603 ! negatively regulates amide metabolic process relationship: RO:0002212 GO:0043603 ! negatively regulates amide metabolic process [Term] id: GO:0034250 name: positive regulation of amide metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "positive regulation of amide metabolism" EXACT [] synonym: "positive regulation of cellular amide metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0034248 ! regulation of amide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043603 ! positively regulates amide metabolic process relationship: RO:0002213 GO:0043603 ! positively regulates amide metabolic process [Term] id: GO:0034251 name: regulation of amide catabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "regulation of amide breakdown" EXACT [] synonym: "regulation of amide catabolism" EXACT [] synonym: "regulation of amide degradation" EXACT [] synonym: "regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0034248 ! regulation of amide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043605 ! regulates amide catabolic process relationship: RO:0002211 GO:0043605 ! regulates amide catabolic process [Term] id: GO:0034252 name: negative regulation of amide catabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "negative regulation of amide breakdown" EXACT [] synonym: "negative regulation of amide catabolism" EXACT [] synonym: "negative regulation of amide degradation" RELATED [] synonym: "negative regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043605 ! negatively regulates amide catabolic process relationship: RO:0002212 GO:0043605 ! negatively regulates amide catabolic process [Term] id: GO:0034253 name: positive regulation of amide catabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "positive regulation of amide breakdown" EXACT [] synonym: "positive regulation of amide catabolism" EXACT [] synonym: "positive regulation of amide degradation" RELATED [] synonym: "positive regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043605 ! positively regulates amide catabolic process relationship: RO:0002213 GO:0043605 ! positively regulates amide catabolic process [Term] id: GO:0034284 name: response to monosaccharide def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] synonym: "response to monosaccharide stimulus" EXACT [GOC:dos] is_a: GO:0009743 ! response to carbohydrate intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide [Term] id: GO:0034329 name: cell junction assembly def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." [GOC:mah] xref: Reactome:R-HSA-446728 "Cell junction organization" is_a: GO:0022607 ! cellular component assembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0030054 ! results in assembly of cell junction relationship: RO:0002588 GO:0030054 ! results in assembly of cell junction property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0034330 name: cell junction organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl subset: goslim_generic synonym: "cell junction assembly and maintenance" EXACT [] synonym: "cell junction biogenesis" RELATED [] synonym: "cell junction organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030054 ! results in organization of cell junction relationship: RO:0002592 GO:0030054 ! results in organization of cell junction [Term] id: GO:0034349 name: glial cell apoptotic process def: "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." [CL:0000125, GOC:mtg_apoptosis, GOC:sart] synonym: "apoptosis of glia" EXACT [] synonym: "apoptosis of glial cells" EXACT [] synonym: "glia apoptosis" EXACT [] synonym: "glia programmed cell death by apoptosis" EXACT [] synonym: "glial cell apoptosis" NARROW [] synonym: "glial cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of glia by apoptosis" EXACT [] synonym: "programmed cell death of glial cells by apoptosis" EXACT [] synonym: "programmed cell death, glia" EXACT [] synonym: "programmed cell death, glial cells" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000125 ! occurs in glial cell relationship: BFO:0000066 CL:0000125 ! occurs in glial cell property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0034350 name: regulation of glial cell apoptotic process def: "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "regulation of glial cell apoptosis" RELATED [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034349 ! regulates glial cell apoptotic process relationship: RO:0002211 GO:0034349 ! regulates glial cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0034351 name: negative regulation of glial cell apoptotic process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "down regulation of glial cell apoptosis" EXACT [] synonym: "down-regulation of glial cell apoptosis" EXACT [] synonym: "downregulation of glial cell apoptosis" EXACT [] synonym: "inhibition of glial cell apoptosis" NARROW [] synonym: "negative regulation of glial cell apoptosis" NARROW [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034349 ! negatively regulates glial cell apoptotic process relationship: RO:0002212 GO:0034349 ! negatively regulates glial cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0034352 name: positive regulation of glial cell apoptotic process def: "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "activation of glial cell apoptosis" NARROW [] synonym: "positive regulation of glial cell apoptosis" NARROW [] synonym: "stimulation of glial cell apoptosis" NARROW [] synonym: "up regulation of glial cell apoptosis" EXACT [] synonym: "up-regulation of glial cell apoptosis" EXACT [] synonym: "upregulation of glial cell apoptosis" EXACT [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034349 ! positively regulates glial cell apoptotic process relationship: RO:0002213 GO:0034349 ! positively regulates glial cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0034390 name: smooth muscle cell apoptotic process def: "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl] synonym: "apoptosis of smooth muscle cells" EXACT [] synonym: "programmed cell death of smooth muscle cells by apoptosis" EXACT [] synonym: "programmed cell death, smooth muscle cells" EXACT [] synonym: "SMC apoptosis" EXACT [] synonym: "smooth muscle cell apoptosis" NARROW [] synonym: "smooth muscle cell programmed cell death by apoptosis" EXACT [] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000192 ! occurs in smooth muscle cell relationship: BFO:0000066 CL:0000192 ! occurs in smooth muscle cell [Term] id: GO:0034391 name: regulation of smooth muscle cell apoptotic process def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "regulation of SMC apoptosis" EXACT [] synonym: "regulation of smooth muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034390 ! regulates smooth muscle cell apoptotic process relationship: RO:0002211 GO:0034390 ! regulates smooth muscle cell apoptotic process [Term] id: GO:0034392 name: negative regulation of smooth muscle cell apoptotic process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "down regulation of smooth muscle cell apoptosis" EXACT [] synonym: "down-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "downregulation of smooth muscle cell apoptosis" EXACT [] synonym: "inhibition of smooth muscle cell apoptosis" NARROW [] synonym: "negative regulation of SMC apoptosis" EXACT [] synonym: "negative regulation of smooth muscle cell apoptosis" NARROW [] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034390 ! negatively regulates smooth muscle cell apoptotic process relationship: RO:0002212 GO:0034390 ! negatively regulates smooth muscle cell apoptotic process [Term] id: GO:0034393 name: positive regulation of smooth muscle cell apoptotic process def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "activation of smooth muscle cell apoptosis" NARROW [] synonym: "positive regulation of SMC apoptosis" EXACT [] synonym: "positive regulation of smooth muscle cell apoptosis" NARROW [] synonym: "stimulation of smooth muscle cell apoptosis" NARROW [] synonym: "up regulation of smooth muscle cell apoptosis" EXACT [] synonym: "up-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "upregulation of smooth muscle cell apoptosis" EXACT [] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034390 ! positively regulates smooth muscle cell apoptotic process relationship: RO:0002213 GO:0034390 ! positively regulates smooth muscle cell apoptotic process [Term] id: GO:0034436 name: glycoprotein transport def: "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah, GOC:rl] is_a: GO:0015031 ! protein transport is_a: GO:1901264 ! carbohydrate derivative transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein [Term] id: GO:0034486 name: vacuolar transmembrane transport def: "The process in which a solute is transported from one side of the vacuolar membrane to the other." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "vacuolar membrane transport" EXACT [] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0002344 GO:0005773 ! results in transport to from or in vacuole relationship: RO:0002344 GO:0005773 ! results in transport to from or in vacuole [Term] id: GO:0034487 name: vacuolar amino acid transmembrane transport def: "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "vacuolar amino acid membrane transport" EXACT [] is_a: GO:0003333 ! amino acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0005774 ! results in transport across vacuolar membrane intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion relationship: RO:0002342 GO:0005774 ! results in transport across vacuolar membrane [Term] id: GO:0034502 name: protein localization to chromosome def: "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." [GOC:mah] synonym: "condensin localization to chromosome" NARROW [] synonym: "protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005694 ! has target end location chromosome relationship: RO:0002339 GO:0005694 ! has target end location chromosome [Term] id: GO:0034504 name: protein localization to nucleus alt_id: GO:0044744 def: "A process in which a protein transports or maintains the localization of another protein to the nucleus." [GOC:ecd] synonym: "protein localisation to nucleus" EXACT [GOC:mah] synonym: "protein localization in cell nucleus" EXACT [] synonym: "protein localization in nucleus" EXACT [GOC:mah] synonym: "protein targeting to nucleus" RELATED [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005634 ! has target end location nucleus relationship: RO:0002339 GO:0005634 ! has target end location nucleus creation_date: 2012-11-07T15:45:54Z [Term] id: GO:0034654 name: nucleobase-containing compound biosynthetic process def: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid anabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid formation" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" NARROW [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:61120 ! has primary output nucleobase-containing molecular entity relationship: RO:0004008 CHEBI:61120 ! has primary output nucleobase-containing molecular entity [Term] id: GO:0034655 name: nucleobase-containing compound catabolic process def: "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] subset: goslim_chembl synonym: "nucleobase, nucleoside, nucleotide and nucleic acid breakdown" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" RELATED [GOC:dph, GOC:tb] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid degradation" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity relationship: RO:0004009 CHEBI:61120 ! has primary input nucleobase-containing molecular entity [Term] id: GO:0034672 name: anterior/posterior pattern specification involved in pronephros development def: "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mah] synonym: "anterior/posterior pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0039017 ! pattern specification involved in pronephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0048793 ! pronephros development [Term] id: GO:0034762 name: regulation of transmembrane transport def: "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "regulation of membrane transport" EXACT [] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055085 ! regulates transmembrane transport relationship: RO:0002211 GO:0055085 ! regulates transmembrane transport [Term] id: GO:0034763 name: negative regulation of transmembrane transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane transport" EXACT [] synonym: "down-regulation of transmembrane transport" EXACT [] synonym: "downregulation of transmembrane transport" EXACT [] synonym: "inhibition of transmembrane transport" NARROW [] synonym: "negative regulation of membrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055085 ! negatively regulates transmembrane transport relationship: RO:0002212 GO:0055085 ! negatively regulates transmembrane transport [Term] id: GO:0034764 name: positive regulation of transmembrane transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "activation of transmembrane transport" NARROW [] synonym: "positive regulation of membrane transport" EXACT [] synonym: "stimulation of transmembrane transport" NARROW [] synonym: "up regulation of transmembrane transport" EXACT [] synonym: "up-regulation of transmembrane transport" EXACT [] synonym: "upregulation of transmembrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055085 ! positively regulates transmembrane transport relationship: RO:0002213 GO:0055085 ! positively regulates transmembrane transport [Term] id: GO:0034765 name: regulation of monoatomic ion transmembrane transport def: "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "regulation of ion membrane transport" EXACT [] synonym: "regulation of ion transmembrane transport" BROAD [] synonym: "regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034220 ! regulates monoatomic ion transmembrane transport relationship: RO:0002211 GO:0034220 ! regulates monoatomic ion transmembrane transport [Term] id: GO:0034766 name: negative regulation of monoatomic ion transmembrane transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane ion transport" EXACT [] synonym: "down-regulation of transmembrane ion transport" EXACT [] synonym: "downregulation of transmembrane ion transport" EXACT [] synonym: "inhibition of transmembrane ion transport" NARROW [] synonym: "negative regulation of ion membrane transport" EXACT [] synonym: "negative regulation of ion transmembrane transport" BROAD [] synonym: "negative regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034220 ! negatively regulates monoatomic ion transmembrane transport relationship: RO:0002212 GO:0034220 ! negatively regulates monoatomic ion transmembrane transport [Term] id: GO:0034767 name: positive regulation of monoatomic ion transmembrane transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "activation of transmembrane ion transport" NARROW [] synonym: "positive regulation of ion membrane transport" EXACT [] synonym: "positive regulation of ion transmembrane transport" BROAD [] synonym: "positive regulation of transmembrane ion transport" EXACT [] synonym: "stimulation of transmembrane ion transport" NARROW [] synonym: "up regulation of transmembrane ion transport" EXACT [] synonym: "up-regulation of transmembrane ion transport" EXACT [] synonym: "upregulation of transmembrane ion transport" EXACT [] is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034220 ! positively regulates monoatomic ion transmembrane transport relationship: RO:0002213 GO:0034220 ! positively regulates monoatomic ion transmembrane transport [Term] id: GO:0034769 name: basement membrane disassembly alt_id: GO:0060881 def: "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." [GOC:sart, PMID:17301221] comment: Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer. synonym: "basal lamina disassembly" RELATED [] is_a: GO:0022617 ! extracellular matrix disassembly is_a: GO:0071711 ! basement membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005604 ! results in disassembly of basement membrane relationship: RO:0002590 GO:0005604 ! results in disassembly of basement membrane created_by: dph creation_date: 2009-08-13T11:27:24Z [Term] id: GO:0035019 name: somatic stem cell population maintenance def: "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089] xref: Reactome:R-HSA-452723 "Transcriptional regulation of pluripotent stem cells" is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000723 ! acts on population of somatic stem cell relationship: RO:0012003 CL:0000723 ! acts on population of somatic stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0035039 name: male pronucleus assembly def: "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." [GOC:bf, PMID:11735001] synonym: "male pronucleus formation" RELATED [GOC:dph] is_a: GO:0006997 ! nucleus organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0001940 ! results in assembly of male pronucleus relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007338 ! single fertilization relationship: RO:0002588 GO:0001940 ! results in assembly of male pronucleus [Term] id: GO:0035040 name: sperm nuclear envelope removal def: "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." [GOC:bf, PMID:11735001] is_a: GO:0051081 ! nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: BFO:0000066 CL:0000019 ! occurs in sperm relationship: BFO:0000066 CL:0000019 ! occurs in sperm relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0035039 ! male pronucleus assembly [Term] id: GO:0035045 name: sperm plasma membrane disassembly def: "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." [GOC:bf, ISBN:0879694238] synonym: "sperm plasma membrane breakdown" EXACT [] synonym: "sperm plasma membrane catabolism" EXACT [] synonym: "sperm plasma membrane degradation" EXACT [] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030397 ! membrane disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0097524 ! results in disassembly of sperm plasma membrane relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0007338 ! single fertilization relationship: RO:0002590 GO:0097524 ! results in disassembly of sperm plasma membrane property_value: RO:0002161 NCBITaxon:58024 [Term] id: GO:0035050 name: embryonic heart tube development def: "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." [GOC:go_curators] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004141 ! results in development of heart tube relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007507 ! heart development relationship: part_of GO:0048568 ! embryonic organ development relationship: RO:0002296 UBERON:0004141 ! results in development of heart tube [Term] id: GO:0035051 name: cardiocyte differentiation def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." [GOC:bf] synonym: "cardiac cell differentiation" EXACT [] synonym: "heart cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002494 ! results in acquisition of features of cardiocyte relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007507 ! heart development relationship: RO:0002315 CL:0002494 ! results in acquisition of features of cardiocyte [Term] id: GO:0035082 name: axoneme assembly alt_id: GO:0035083 alt_id: GO:0035084 def: "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. synonym: "axoneme biogenesis" RELATED [GOC:mah] synonym: "ciliary axoneme assembly" EXACT [] synonym: "cilium axoneme assembly" EXACT [] synonym: "cilium axoneme biogenesis" RELATED [GOC:mah] synonym: "flagellar axoneme assembly" EXACT [] synonym: "flagellum axoneme assembly" EXACT [] is_a: GO:0001578 ! microtubule bundle formation is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005930 ! results in assembly of axoneme relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0060271 ! cilium assembly relationship: RO:0002588 GO:0005930 ! results in assembly of axoneme property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0035107 name: appendage morphogenesis def: "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000026 ! results in morphogenesis of appendage relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048736 ! appendage development relationship: RO:0002298 UBERON:0000026 ! results in morphogenesis of appendage [Term] id: GO:0035108 name: limb morphogenesis def: "The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping." [UBERON:0002101] synonym: "limb bud morphogenesis" NARROW [GOC:dph] is_a: GO:0035107 ! appendage morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002101 ! results in morphogenesis of limb relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0060173 ! limb development relationship: RO:0002298 UBERON:0002101 ! results in morphogenesis of limb [Term] id: GO:0035112 name: genitalia morphogenesis def: "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." [GOC:bf] synonym: "genital morphogenesis" RELATED [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000990 ! results in morphogenesis of reproductive system relationship: part_of GO:0048806 ! genitalia development relationship: RO:0002298 UBERON:0000990 ! results in morphogenesis of reproductive system [Term] id: GO:0035136 name: forelimb morphogenesis alt_id: GO:0035140 def: "The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human." [GOC:go_curators] synonym: "arm morphogenesis" NARROW [GOC:bf, GOC:cjm] is_a: GO:0035108 ! limb morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002102 ! results in morphogenesis of forelimb relationship: RO:0002298 UBERON:0002102 ! results in morphogenesis of forelimb [Term] id: GO:0035137 name: hindlimb morphogenesis def: "The process in which the anatomical structures of the hindlimb are generated and organized." [GOC:go_curators] is_a: GO:0035108 ! limb morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002103 ! results in morphogenesis of hindlimb relationship: RO:0002298 UBERON:0002103 ! results in morphogenesis of hindlimb [Term] id: GO:0035148 name: tube formation def: "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." [GOC:bf] synonym: "lumen formation in an anatomical structure" RELATED [GOC:dph, GOC:mah] synonym: "tube lumen formation" EXACT [GOC:dph, GOC:mah] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000025 ! results in formation of anatomical entity tube relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0035239 ! tube morphogenesis relationship: RO:0002297 UBERON:0000025 ! results in formation of anatomical entity tube [Term] id: GO:0035190 name: syncytial nuclear migration def: "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisions and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." [GOC:bf, ISBN:0879694238, PMID:8314839] is_a: GO:0007097 ! nuclear migration intersection_of: GO:0007097 ! nuclear migration intersection_of: BFO:0000066 CL:0000228 ! occurs in multinucleate cell relationship: BFO:0000066 CL:0000228 ! occurs in multinucleate cell relationship: in_taxon NCBITaxon:50557 ! Insecta relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm [Term] id: GO:0035234 name: ectopic germ cell programmed cell death def: "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." [PMID:12814944] synonym: "programmed cell death of ectopic germ cells" EXACT [] synonym: "programmed cell death, ectopic germ cells" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010623 ! programmed cell death involved in cell development intersection_of: GO:0012501 ! programmed cell death intersection_of: BFO:0000066 CL:0000586 ! occurs in germ cell relationship: BFO:0000066 CL:0000586 ! occurs in germ cell [Term] id: GO:0035239 name: tube morphogenesis def: "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:bf, PMID:14624839] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000025 ! results in morphogenesis of tube relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0035295 ! tube development relationship: RO:0002298 UBERON:0000025 ! results in morphogenesis of tube [Term] id: GO:0035260 name: internal genitalia morphogenesis def: "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [PMID:24793987, PMID:25247640] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004175 ! results in morphogenesis of internal genitalia relationship: RO:0002298 UBERON:0004175 ! results in morphogenesis of internal genitalia [Term] id: GO:0035261 name: external genitalia morphogenesis def: "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [PMID:24793987, PMID:25247640] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004176 ! results in morphogenesis of external genitalia relationship: RO:0002298 UBERON:0004176 ! results in morphogenesis of external genitalia [Term] id: GO:0035262 name: gonad morphogenesis def: "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." [ISBN:0198612001] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000991 ! results in morphogenesis of gonad relationship: part_of GO:0008406 ! gonad development relationship: RO:0002298 UBERON:0000991 ! results in morphogenesis of gonad [Term] id: GO:0035264 name: multicellular organism growth def: "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." [GOC:bf, GOC:curators, GOC:dph, GOC:tb] synonym: "body growth" RELATED [] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0000468 ! results in growth of multicellular organism relationship: RO:0002343 UBERON:0000468 ! results in growth of multicellular organism property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0035265 name: organ growth def: "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." [GOC:bf, ISBN:0471245208, ISBN:0721662544] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0000062 ! results in growth of organ relationship: RO:0002343 UBERON:0000062 ! results in growth of organ property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0035270 name: endocrine system development def: "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." [GOC:bf, Wikipedia:Development_of_the_endocrine_system] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000949 ! results in development of endocrine system relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0000949 ! results in development of endocrine system [Term] id: GO:0035272 name: exocrine system development def: "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." [GOC:bf, Wikipedia:Exocrine_gland] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002330 ! results in development of exocrine system relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0002330 ! results in development of exocrine system [Term] id: GO:0035282 name: segmentation def: "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." [PMID:10611687, PMID:9706689] xref: Wikipedia:Segmentation_(biology) is_a: GO:0003002 ! regionalization property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0035290 name: trunk segmentation def: "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." [PMID:1360402] is_a: GO:0035282 ! segmentation relationship: part_of GO:0007350 ! blastoderm segmentation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0035295 name: tube development def: "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000025 ! results in development of tube relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007275 ! multicellular organism development relationship: RO:0002296 UBERON:0000025 ! results in development of tube [Term] id: GO:0035322 name: mesenchymal cell migration involved in limb bud formation def: "The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud." [GOC:dgh] is_a: GO:0090497 ! mesenchymal cell migration intersection_of: GO:0090497 ! mesenchymal cell migration intersection_of: part_of GO:0060174 ! limb bud formation relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0090496 ! mesenchyme migration involved in limb bud formation created_by: bf creation_date: 2010-02-24T02:05:14Z [Term] id: GO:0035372 name: protein localization to microtubule def: "A process in which a protein is transported to, or maintained at, a microtubule." [GOC:bf, GOC:lb] synonym: "protein localisation to microtubule" EXACT [GOC:mah] is_a: GO:0072698 ! protein localization to microtubule cytoskeleton intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005874 ! has target end location microtubule relationship: RO:0002339 GO:0005874 ! has target end location microtubule created_by: bf creation_date: 2010-03-11T11:00:56Z [Term] id: GO:0035377 name: transepithelial water transport def: "The directed movement of water (H2O) from one side of an epithelium to the other." [GOC:yaf] is_a: GO:0006833 ! water transport is_a: GO:0042045 ! epithelial fluid transport intersection_of: GO:0042044 ! fluid transport intersection_of: RO:0002342 UBERON:0000483 ! results in transport across epithelium intersection_of: RO:0004009 CHEBI:15377 ! has primary input water created_by: bf creation_date: 2010-03-18T10:55:38Z [Term] id: GO:0035418 name: protein localization to synapse def: "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:bf] synonym: "protein localisation to synapse" EXACT [GOC:mah] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0045202 ! has target end location synapse relationship: RO:0002339 GO:0045202 ! has target end location synapse created_by: bf creation_date: 2010-03-29T10:58:53Z [Term] id: GO:0035433 name: acetate transmembrane transport def: "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "acetate membrane transport" EXACT [] is_a: GO:0006846 ! acetate transport is_a: GO:1905039 ! carboxylic acid transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate created_by: bf creation_date: 2010-04-08T10:59:01Z [Term] id: GO:0035441 name: cell migration involved in vasculogenesis def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." [GOC:dgh] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001570 ! vasculogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001570 ! vasculogenesis created_by: bf creation_date: 2010-04-09T03:53:01Z [Term] id: GO:0035556 name: intracellular signal transduction alt_id: GO:0007242 alt_id: GO:0007243 alt_id: GO:0023013 alt_id: GO:0023034 def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] subset: goslim_drosophila synonym: "intracellular signal transduction pathway" NARROW [] synonym: "intracellular signaling cascade" RELATED [GOC:signaling] synonym: "intracellular signaling pathway" RELATED [] synonym: "signal transmission via intracellular cascade" NARROW [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure relationship: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure created_by: bf creation_date: 2010-05-14T01:14:37Z [Term] id: GO:0035592 name: establishment of protein localization to extracellular region def: "The directed movement of a protein to a specific location within the extracellular region." [GOC:bf, GOC:BHF] synonym: "establishment of protein localisation in extracellular region" EXACT [GOC:mah] synonym: "establishment of protein localization in extracellular region" EXACT [] is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region relationship: RO:0002339 GO:0005576 ! has target end location extracellular region created_by: bf creation_date: 2010-11-09T10:25:08Z [Term] id: GO:0035622 name: intrahepatic bile duct development def: "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." [GOC:bf, PMID:20614624] synonym: "IHBD development" EXACT [PMID:20614624] synonym: "intrahepatic biliary duct development" EXACT [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003704 ! results in development of intrahepatic bile duct relationship: part_of GO:0001889 ! liver development relationship: RO:0002296 UBERON:0003704 ! results in development of intrahepatic bile duct created_by: bf creation_date: 2010-12-08T04:10:50Z [Term] id: GO:0035628 name: cystic duct development def: "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct." [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001152 ! results in development of cystic duct relationship: RO:0002296 UBERON:0001152 ! results in development of cystic duct created_by: bf creation_date: 2010-12-10T01:24:28Z [Term] id: GO:0035645 name: enteric smooth muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." [CL:0002504, GOC:BHF] synonym: "intestinal smooth muscle cell differentiation" EXACT [CL:0002504] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002504 ! results in acquisition of features of enteric smooth muscle cell relationship: part_of GO:0048565 ! digestive tract development relationship: RO:0002315 CL:0002504 ! results in acquisition of features of enteric smooth muscle cell created_by: bf creation_date: 2011-01-21T02:58:58Z [Term] id: GO:0035701 name: hematopoietic stem cell migration def: "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:BHF, PMID:20234092] synonym: "hemopoietic stem cell migration" EXACT [CL:0000037] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000037 ! results in movement of hematopoietic stem cell relationship: RO:0002565 CL:0000037 ! results in movement of hematopoietic stem cell property_value: RO:0002161 NCBITaxon:4890 created_by: bf creation_date: 2011-02-28T03:20:36Z [Term] id: GO:0035719 name: tRNA import into nucleus def: "The directed movement of tRNA from the cytoplasm to the nucleus." [GOC:vw, PMID:20032305] synonym: "retrograde tRNA transport into nucleus" EXACT [GOC:vw, PMID:20032305] synonym: "tRNA nuclear import" EXACT [GOC:vw] is_a: GO:0006404 ! RNA import into nucleus is_a: GO:0051031 ! tRNA transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0031981 ! has target end location nuclear lumen intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope intersection_of: RO:0004009 CHEBI:17843 ! has primary input transfer RNA created_by: bf creation_date: 2011-03-03T04:32:35Z [Term] id: GO:0035725 name: sodium ion transmembrane transport def: "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "sodium ion membrane transport" EXACT [] is_a: GO:0006814 ! sodium ion transport is_a: GO:0098655 ! monoatomic cation transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) created_by: bf creation_date: 2011-03-10T02:52:36Z [Term] id: GO:0035735 name: intraciliary transport involved in cilium assembly def: "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." [GOC:bf, GOC:cilia] synonym: "intraciliary transport involved in cilium morphogenesis" RELATED [] synonym: "intraflagellar transport" BROAD [] synonym: "intraflagellar transport involved in cilium morphogenesis" RELATED [] xref: Reactome:R-HSA-5620924 "Intraflagellar transport" is_a: GO:0042073 ! intraciliary transport intersection_of: GO:0042073 ! intraciliary transport intersection_of: part_of GO:0060271 ! cilium assembly relationship: part_of GO:0060271 ! cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: bf creation_date: 2011-03-17T10:55:42Z [Term] id: GO:0035736 name: cell proliferation involved in compound eye morphogenesis def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." [GOC:bf, GOC:sart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001745 ! compound eye morphogenesis relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0001745 ! compound eye morphogenesis created_by: bf creation_date: 2011-03-17T10:57:03Z [Term] id: GO:0035773 name: insulin secretion involved in cellular response to glucose stimulus def: "The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus." [GOC:bf, GOC:yaf, PMID:8492079] synonym: "insulin secretion involved in cellular response to glucose" EXACT [GOC:bf] is_a: GO:0030073 ! insulin secretion is_a: GO:0051649 ! establishment of localization in cell intersection_of: GO:0030073 ! insulin secretion intersection_of: part_of GO:0071333 ! cellular response to glucose stimulus relationship: part_of GO:0071333 ! cellular response to glucose stimulus created_by: bf creation_date: 2011-04-01T01:14:40Z [Term] id: GO:0035774 name: positive regulation of insulin secretion involved in cellular response to glucose stimulus def: "Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:bf, GOC:yaf] synonym: "positive regulation of insulin secretion in response to glucose" EXACT [GOC:bf] is_a: GO:0032024 ! positive regulation of insulin secretion is_a: GO:0061178 ! regulation of insulin secretion involved in cellular response to glucose stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035773 ! positively regulates insulin secretion involved in cellular response to glucose stimulus relationship: RO:0002213 GO:0035773 ! positively regulates insulin secretion involved in cellular response to glucose stimulus created_by: bf creation_date: 2011-04-01T01:49:09Z [Term] id: GO:0035778 name: pronephric nephron tubule epithelial cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] is_a: GO:0039014 ! cell differentiation involved in pronephros development is_a: GO:0072160 ! nephron tubule epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000090 ! results in acquisition of features of pronephric nephron tubule epithelial cell relationship: part_of GO:0039020 ! pronephric nephron tubule development relationship: RO:0002315 CL:1000090 ! results in acquisition of features of pronephric nephron tubule epithelial cell created_by: bf creation_date: 2011-04-04T11:07:47Z [Term] id: GO:0035779 name: angioblast cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." [CL:0000566, GOC:yaf] synonym: "angioblastic mesenchymal cell differentiation" EXACT [CL:0000566] is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000566 ! results in acquisition of features of angioblastic mesenchymal cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001568 ! blood vessel development relationship: RO:0002315 CL:0000566 ! results in acquisition of features of angioblastic mesenchymal cell created_by: bf creation_date: 2011-04-04T11:10:38Z [Term] id: GO:0035787 name: cell migration involved in kidney development def: "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001822 ! kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development created_by: bf creation_date: 2011-04-06T10:39:52Z [Term] id: GO:0035788 name: cell migration involved in metanephros development def: "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] synonym: "cell migration involved in metanephric kidney development" EXACT [GOC:bf] is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: bf creation_date: 2011-04-06T10:42:21Z [Term] id: GO:0035799 name: ureter maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:17881463] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0000056 ! results in maturation of ureter relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072189 ! ureter development relationship: RO:0002299 UBERON:0000056 ! results in maturation of ureter created_by: bf creation_date: 2011-04-14T01:13:39Z [Term] id: GO:0035809 name: regulation of urine volume def: "Any process that modulates the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf] synonym: "regulation of urinary volume" EXACT [] synonym: "regulation of urine flow" EXACT [] is_a: GO:0003014 ! renal system process is_a: GO:0050878 ! regulation of body fluid levels property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-04-20T01:17:38Z [Term] id: GO:0035834 name: indole alkaloid metabolic process def: "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid metabolism" EXACT [GOC:bf] is_a: GO:0009820 ! alkaloid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:38958 ! has primary input or output indole alkaloid relationship: RO:0004007 CHEBI:38958 ! has primary input or output indole alkaloid created_by: bf creation_date: 2011-05-04T03:17:44Z [Term] id: GO:0035835 name: indole alkaloid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid anabolism" EXACT [GOC:bf] synonym: "indole alkaloid biosynthesis" EXACT [GOC:bf] synonym: "indole alkaloid formation" EXACT [GOC:bf] synonym: "indole alkaloid synthesis" EXACT [GOC:bf] is_a: GO:0009821 ! alkaloid biosynthetic process is_a: GO:0035834 ! indole alkaloid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:38958 ! has primary output indole alkaloid relationship: RO:0004008 CHEBI:38958 ! has primary output indole alkaloid created_by: bf creation_date: 2011-05-04T03:18:31Z [Term] id: GO:0035844 name: cloaca development def: "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." [GOC:dgh, ISBN:0582227089] synonym: "cloacal development" EXACT [GOC:bf] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000162 ! results in development of cloaca relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001655 ! urogenital system development relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: RO:0002296 UBERON:0000162 ! results in development of cloaca created_by: bf creation_date: 2011-05-06T01:54:35Z [Term] id: GO:0035846 name: oviduct epithelium development def: "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." [GOC:yaf, PMID:34496237] synonym: "fallopian tube epithelium development" NARROW [GOC:yaf] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004804 ! results in development of oviduct epithelium relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0060066 ! oviduct development relationship: RO:0002296 UBERON:0004804 ! results in development of oviduct epithelium created_by: bf creation_date: 2011-05-10T10:53:05Z [Term] id: GO:0035847 name: uterine epithelium development def: "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:bf, GOC:yaf] synonym: "uterus epithelial development" EXACT [GOC:yaf] is_a: GO:0035846 ! oviduct epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006955 ! results in development of uterine epithelium relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0060065 ! uterus development relationship: RO:0002296 UBERON:0006955 ! results in development of uterine epithelium created_by: bf creation_date: 2011-05-10T10:57:45Z [Term] id: GO:0035848 name: oviduct morphogenesis def: "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:yaf, PMID:22918811] synonym: "fallopian tube morphogenesis" NARROW [GOC:yaf] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000993 ! results in morphogenesis of oviduct relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0060066 ! oviduct development relationship: RO:0002298 UBERON:0000993 ! results in morphogenesis of oviduct created_by: bf creation_date: 2011-05-10T11:01:20Z [Term] id: GO:0035850 name: epithelial cell differentiation involved in kidney development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: part_of GO:0001822 ! kidney development created_by: bf creation_date: 2011-05-11T11:34:21Z [Term] id: GO:0035855 name: megakaryocyte development def: "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk] synonym: "megakaryocyte cell development" EXACT [GOC:bf] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0000556 ! results in development of megakaryocyte relationship: part_of GO:0030219 ! megakaryocyte differentiation relationship: RO:0002296 CL:0000556 ! results in development of megakaryocyte created_by: bf creation_date: 2011-05-13T01:28:06Z [Term] id: GO:0035869 name: ciliary transition zone def: "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." [GOC:cilia, GOC:kmv, PMID:21422230] comment: Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone. synonym: "cilial transition zone" EXACT [] synonym: "cilium transition zone" EXACT [] synonym: "connecting cilium" RELATED [] is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005929 ! cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: bf creation_date: 2011-05-25T03:09:58Z [Term] id: GO:0035878 name: nail development def: "The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it." [GOC:bf, ISBN:0323025781, UBERON:0001705, Wikipedia:Nail_(anatomy)] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001705 ! results in development of nail relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0060173 ! limb development relationship: RO:0002296 UBERON:0001705 ! results in development of nail created_by: bf creation_date: 2011-05-31T02:30:34Z [Term] id: GO:0035883 name: enteroendocrine cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." [CL:0000164, GOC:bf] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000164 ! results in acquisition of features of enteroendocrine cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002315 CL:0000164 ! results in acquisition of features of enteroendocrine cell created_by: bf creation_date: 2011-06-06T11:48:51Z [Term] id: GO:0035886 name: vascular associated smooth muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." [GOC:sl, PMID:16151017, PMID:18267954] synonym: "vascular smooth muscle cell differentiation" EXACT [] synonym: "VSMC differentiation" EXACT [PMID:16151017] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000359 ! results in acquisition of features of vascular associated smooth muscle cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001944 ! vasculature development relationship: RO:0002315 CL:0000359 ! results in acquisition of features of vascular associated smooth muscle cell created_by: bf creation_date: 2011-06-08T11:23:52Z [Term] id: GO:0035887 name: aortic smooth muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." [GOC:sl] is_a: GO:0035886 ! vascular associated smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002539 ! results in acquisition of features of aortic smooth muscle cell relationship: RO:0002315 CL:0002539 ! results in acquisition of features of aortic smooth muscle cell created_by: bf creation_date: 2011-06-08T11:34:26Z [Term] id: GO:0035904 name: aorta development def: "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0060840 ! artery development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000947 ! results in development of aorta relationship: RO:0002296 UBERON:0000947 ! results in development of aorta created_by: bf creation_date: 2011-06-24T11:00:07Z [Term] id: GO:0035905 name: ascending aorta development def: "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001496 ! results in development of ascending aorta relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035904 ! aorta development relationship: RO:0002296 UBERON:0001496 ! results in development of ascending aorta created_by: bf creation_date: 2011-06-24T11:02:01Z [Term] id: GO:0035906 name: descending aorta development def: "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001514 ! results in development of descending aorta relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035904 ! aorta development relationship: RO:0002296 UBERON:0001514 ! results in development of descending aorta created_by: bf creation_date: 2011-06-24T11:05:22Z [Term] id: GO:0035907 name: dorsal aorta development def: "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035904 ! aorta development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005805 ! results in development of dorsal aorta relationship: RO:0002296 UBERON:0005805 ! results in development of dorsal aorta created_by: bf creation_date: 2011-06-24T11:07:01Z [Term] id: GO:0035909 name: aorta morphogenesis def: "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000947 ! results in morphogenesis of aorta relationship: part_of GO:0035904 ! aorta development relationship: RO:0002298 UBERON:0000947 ! results in morphogenesis of aorta created_by: bf creation_date: 2011-06-24T11:11:11Z [Term] id: GO:0035910 name: ascending aorta morphogenesis def: "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001496 ! results in morphogenesis of ascending aorta relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035905 ! ascending aorta development relationship: part_of GO:0035909 ! aorta morphogenesis relationship: RO:0002298 UBERON:0001496 ! results in morphogenesis of ascending aorta created_by: bf creation_date: 2011-06-24T11:14:52Z [Term] id: GO:0035911 name: descending aorta morphogenesis def: "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001514 ! results in morphogenesis of descending aorta relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035906 ! descending aorta development relationship: part_of GO:0035909 ! aorta morphogenesis relationship: RO:0002298 UBERON:0001514 ! results in morphogenesis of descending aorta created_by: bf creation_date: 2011-06-24T11:19:24Z [Term] id: GO:0035912 name: dorsal aorta morphogenesis def: "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035909 ! aorta morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005805 ! results in morphogenesis of dorsal aorta relationship: part_of GO:0035907 ! dorsal aorta development relationship: RO:0002298 UBERON:0005805 ! results in morphogenesis of dorsal aorta created_by: bf creation_date: 2011-06-24T11:22:14Z [Term] id: GO:0035914 name: skeletal muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." [CL:0000188, GOC:BHF, GOC:vk] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000188 ! results in acquisition of features of cell of skeletal muscle relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: RO:0002315 CL:0000188 ! results in acquisition of features of cell of skeletal muscle created_by: bf creation_date: 2011-06-24T02:36:19Z [Term] id: GO:0035929 name: steroid hormone secretion def: "The regulated release of any steroid that acts as a hormone into the circulatory system." [GOC:sl] is_a: GO:0060986 ! endocrine hormone secretion is_a: GO:0140353 ! lipid export from cell intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:26764 ! has primary input steroid hormone relationship: RO:0004009 CHEBI:26764 ! has primary input steroid hormone property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-20T01:01:00Z [Term] id: GO:0035935 name: androgen secretion def: "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." [GOC:sl] is_a: GO:0035929 ! steroid hormone secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-20T01:11:31Z [Term] id: GO:0035981 name: tongue muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell." [CL:0002673, GOC:yaf, PMID:3393851] is_a: GO:0098528 ! skeletal muscle fiber differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002673 ! results in acquisition of features of tongue muscle cell relationship: RO:0002315 CL:0002673 ! results in acquisition of features of tongue muscle cell created_by: bf creation_date: 2011-08-22T01:35:16Z [Term] id: GO:0035987 name: endodermal cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." [CL:0000223, GOC:yaf, PMID:17624332] synonym: "endoderm cell differentiation" EXACT [CL:0000223] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000223 ! results in acquisition of features of endodermal cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0001706 ! endoderm formation relationship: RO:0002315 CL:0000223 ! results in acquisition of features of endodermal cell created_by: bf creation_date: 2011-08-25T04:50:36Z [Term] id: GO:0035989 name: tendon development def: "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." [GOC:yaf, PMID:21412429, UBERON:0000043] synonym: "sinew development" RELATED [UBERON:0000043] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000043 ! results in development of tendon relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0000043 ! results in development of tendon created_by: bf creation_date: 2011-08-26T04:14:30Z [Term] id: GO:0035990 name: tendon cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance." [CL:0000388, GOC:yaf, PMID:21412429] synonym: "muscle attachment cell differentiation" EXACT [CL:0000388] synonym: "tenocyte differentiation" RELATED [CL:0000388] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000388 ! results in acquisition of features of tendon cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035992 ! tendon formation relationship: RO:0002315 CL:0000388 ! results in acquisition of features of tendon cell created_by: bf creation_date: 2011-08-26T04:16:06Z [Term] id: GO:0035992 name: tendon formation def: "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." [GOC:yaf, PMID:17567668, UBERON:0000043] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000043 ! results in formation of anatomical entity tendon relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035989 ! tendon development relationship: RO:0002297 UBERON:0000043 ! results in formation of anatomical entity tendon created_by: bf creation_date: 2011-08-30T01:35:10Z [Term] id: GO:0035993 name: deltoid tuberosity development def: "The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase." [GOC:yaf, PMID:17567668, UBERON:0002498, Wikipedia:Deltoid_tuberosity] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002498 ! results in development of deltopectoral crest relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0060173 ! limb development relationship: part_of GO:0060348 ! bone development relationship: RO:0002296 UBERON:0002498 ! results in development of deltopectoral crest created_by: bf creation_date: 2011-08-30T01:46:53Z [Term] id: GO:0036022 name: limb joint morphogenesis def: "The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner." [GOC:bf] synonym: "knee morphogenesis" NARROW [GOC:bf] synonym: "leg joint morphogenesis" NARROW [GOC:bf] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003657 ! results in morphogenesis of limb joint relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0035108 ! limb morphogenesis relationship: RO:0002298 UBERON:0003657 ! results in morphogenesis of limb joint created_by: bf creation_date: 2011-10-13T04:52:59Z [Term] id: GO:0036072 name: direct ossification def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." [GO_REF:0000034] is_a: GO:0001503 ! ossification created_by: bf creation_date: 2011-12-19T01:47:22Z [Term] id: GO:0036093 name: germ cell proliferation def: "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." [CL:0000586, GOC:kmv] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000586 ! acts on population of germ cell relationship: part_of GO:0007276 ! gamete generation relationship: RO:0012003 CL:0000586 ! acts on population of germ cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: bf creation_date: 2012-01-17T04:06:27Z [Term] id: GO:0036099 name: female germ-line stem cell population maintenance def: "The process by which an organism or tissue maintains a population of female germ-line stem cells." [GOC:sart] is_a: GO:0030718 ! germ-line stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: RO:0012003 CL:0000022 ! acts on population of female germ line stem cell relationship: RO:0012003 CL:0000022 ! acts on population of female germ line stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2012-01-26T01:58:10Z [Term] id: GO:0036135 name: Schwann cell migration def: "The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function." [CL:0002573, PMID:20335460] is_a: GO:0008347 ! glial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0002573 ! results in movement of Schwann cell relationship: RO:0002565 CL:0002573 ! results in movement of Schwann cell created_by: bf creation_date: 2012-03-06T10:44:39Z [Term] id: GO:0036145 name: dendritic cell homeostasis def: "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000451, GOC:uh, PMID:12570827, PMID:19176316] synonym: "DC homeostasis" RELATED [PMID:19176316] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000451 ! acts on population of dendritic cell relationship: RO:0012003 CL:0000451 ! acts on population of dendritic cell created_by: bf creation_date: 2012-03-12T11:05:36Z [Term] id: GO:0036194 name: muscle cell projection def: "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] synonym: "muscle arm" NARROW [GOC:kmv] synonym: "myocyte projection" EXACT [CL:0000187] synonym: "myopodia" NARROW [GOC:kmv] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000187 ! muscle cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000187 ! muscle cell created_by: bf creation_date: 2012-04-20T10:20:47Z [Term] id: GO:0036195 name: muscle cell projection membrane def: "The portion of the plasma membrane surrounding a muscle cell projection." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] is_a: GO:0031253 ! cell projection membrane intersection_of: GO:0031253 ! cell projection membrane intersection_of: part_of GO:0036194 ! muscle cell projection relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0036194 ! muscle cell projection created_by: bf creation_date: 2012-04-20T10:21:51Z [Term] id: GO:0036293 name: response to decreased oxygen levels def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." [GOC:al] comment: This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'. synonym: "response to lowered oxygen levels" EXACT [GOC:bf] is_a: GO:0070482 ! response to oxygen levels created_by: bf creation_date: 2012-07-20T01:05:46Z [Term] id: GO:0036304 name: umbilical cord morphogenesis def: "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:gr, PMID:15107403] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002331 ! results in morphogenesis of umbilical cord relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0061027 ! umbilical cord development relationship: RO:0002298 UBERON:0002331 ! results in morphogenesis of umbilical cord created_by: bf creation_date: 2012-08-08T10:12:11Z [Term] id: GO:0036305 name: ameloblast differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ." [CL:0000059] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000059 ! results in acquisition of features of ameloblast relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002315 CL:0000059 ! results in acquisition of features of ameloblast property_value: RO:0002161 NCBITaxon:8782 created_by: bf creation_date: 2012-08-08T13:49:15Z [Term] id: GO:0036333 name: hepatocyte homeostasis def: "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." [CL:0000182, GOC:nhn, PMID:19878874] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000182 ! acts on population of hepatocyte relationship: RO:0012003 CL:0000182 ! acts on population of hepatocyte property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2012-09-05T10:17:07Z [Term] id: GO:0036334 name: epidermal stem cell homeostasis def: "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." [CL:1000428, GOC:nhn, PMID:17666529] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:1000428 ! acts on population of stem cell of epidermis relationship: RO:0012003 CL:1000428 ! acts on population of stem cell of epidermis property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2012-09-05T10:21:23Z [Term] id: GO:0036336 name: dendritic cell migration def: "The movement of a dendritic cell within or between different tissues and organs of the body." [CL:0000451, GOC:nhn, PMID:19339990] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000451 ! results in movement of dendritic cell relationship: RO:0002565 CL:0000451 ! results in movement of dendritic cell created_by: bf creation_date: 2012-09-05T10:24:46Z [Term] id: GO:0036342 name: post-anal tail morphogenesis def: "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance." [GOC:bf, GOC:kmv, Wikipedia:Chordate] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007812 ! results in morphogenesis of post-anal tail relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002298 UBERON:0007812 ! results in morphogenesis of post-anal tail created_by: bf creation_date: 2012-09-11T13:54:49Z [Term] id: GO:0036376 name: sodium ion export across plasma membrane alt_id: GO:0071436 alt_id: GO:0098667 def: "The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:vw, PMID:14674689] synonym: "sodium export" RELATED [GOC:mah] synonym: "sodium ion export" RELATED [] synonym: "sodium ion export from cell" EXACT [] is_a: GO:0035725 ! sodium ion transmembrane transport is_a: GO:0140115 ! export across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) created_by: mah creation_date: 2009-12-16T11:13:55Z [Term] id: GO:0036477 name: somatodendritic compartment def: "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." [GOC:pad, GOC:PARL] is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000540 ! neuron created_by: bf creation_date: 2014-07-24T10:06:19Z [Term] id: GO:0036484 name: trunk neural crest cell migration def: "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." [GOC:bf, GOC:mat, GOC:PARL, PMID:2387238] synonym: "trunk NCC migration" EXACT [PMID:2387238] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000011 ! results in movement of migratory trunk neural crest cell relationship: part_of GO:0035290 ! trunk segmentation relationship: RO:0002565 CL:0000011 ! results in movement of migratory trunk neural crest cell created_by: bf creation_date: 2014-08-26T15:27:44Z [Term] id: GO:0036504 name: Golgi membrane fusion def: "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." [GOC:bf, GOC:PARL, PMID:12473691] synonym: "Golgi apparatus membrane fusion" EXACT [] synonym: "membrane fusion involved in Golgi reassembly" EXACT [GOC:bf] synonym: "post-mitotic fusion of Golgi membranes" EXACT [PMID:10811609] is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: RO:0012008 GO:0000139 ! results in fusion of Golgi membrane relationship: part_of GO:0090168 ! Golgi reassembly relationship: RO:0012008 GO:0000139 ! results in fusion of Golgi membrane created_by: bf creation_date: 2015-05-21T10:05:06Z [Term] id: GO:0039006 name: pronephric nephron tubule formation def: "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros." [GOC:mtg_kidney_jan10] synonym: "pronephric tubule formation" EXACT [GOC:mtg_kidney_jan10] synonym: "pronephros tubule formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005310 ! results in formation of anatomical entity pronephric nephron tubule relationship: part_of GO:0039008 ! pronephric nephron tubule morphogenesis relationship: part_of GO:0072116 ! pronephros formation relationship: RO:0002297 UBERON:0005310 ! results in formation of anatomical entity pronephric nephron tubule created_by: bf creation_date: 2010-07-02T09:37:27Z [Term] id: GO:0039007 name: pronephric nephron morphogenesis def: "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005309 ! results in morphogenesis of pronephric nephron relationship: part_of GO:0039019 ! pronephric nephron development relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: RO:0002298 UBERON:0005309 ! results in morphogenesis of pronephric nephron created_by: bf creation_date: 2010-07-02T09:38:53Z [Term] id: GO:0039008 name: pronephric nephron tubule morphogenesis def: "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron." [GOC:mtg_kidney_jan10, ZFA:00001558] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005310 ! results in morphogenesis of pronephric nephron tubule relationship: part_of GO:0039007 ! pronephric nephron morphogenesis relationship: part_of GO:0039020 ! pronephric nephron tubule development relationship: RO:0002298 UBERON:0005310 ! results in morphogenesis of pronephric nephron tubule created_by: bf creation_date: 2010-07-02T09:45:55Z [Term] id: GO:0039014 name: cell differentiation involved in pronephros development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "cell differentiation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T09:59:25Z [Term] id: GO:0039015 name: cell proliferation involved in pronephros development def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros." [GOC:mtg_kidney_jan10] synonym: "cell proliferation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:01:49Z [Term] id: GO:0039016 name: cell-cell signaling involved in pronephros development def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signaling involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in pronephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:03:16Z [Term] id: GO:0039017 name: pattern specification involved in pronephros development def: "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:04:39Z [Term] id: GO:0039019 name: pronephric nephron development def: "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10, XAO:00002785] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005309 ! results in development of pronephric nephron relationship: part_of GO:0048793 ! pronephros development relationship: RO:0002296 UBERON:0005309 ! results in development of pronephric nephron created_by: bf creation_date: 2010-07-02T10:10:20Z [Term] id: GO:0039020 name: pronephric nephron tubule development def: "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct." [GOC:mtg_kidney_jan10, PMID:19909807, PMID:9268568] is_a: GO:0072080 ! nephron tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005310 ! results in development of pronephric nephron tubule relationship: part_of GO:0039019 ! pronephric nephron development relationship: RO:0002296 UBERON:0005310 ! results in development of pronephric nephron tubule created_by: bf creation_date: 2010-07-02T10:11:36Z [Term] id: GO:0039022 name: pronephric duct development def: "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney." [GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003060 ! results in development of pronephric duct relationship: part_of GO:0048793 ! pronephros development relationship: RO:0002296 UBERON:0003060 ! results in development of pronephric duct created_by: bf creation_date: 2010-07-02T10:15:03Z [Term] id: GO:0039023 name: pronephric duct morphogenesis def: "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney." [GOC:mtg_kidney_jan10, XAO:0000063, ZFA:0000150] is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003060 ! results in morphogenesis of pronephric duct relationship: part_of GO:0039022 ! pronephric duct development relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: RO:0002298 UBERON:0003060 ! results in morphogenesis of pronephric duct created_by: bf creation_date: 2010-07-02T10:18:09Z [Term] id: GO:0040007 name: growth alt_id: GO:0048590 def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma] comment: See also the biological process term 'cell growth ; GO:0016049'. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_pir subset: goslim_plant synonym: "growth pattern" RELATED [] synonym: "non-developmental growth" RELATED [GOC:mah] is_a: GO:0008150 ! biological process relationship: in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0040008 name: regulation of growth def: "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0040007 ! regulates growth relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0040007 ! regulates growth [Term] id: GO:0040011 name: locomotion def: "Self-propelled movement of a cell or organism from one location to another." [GOC:dgh] subset: goslim_chembl subset: goslim_pir is_a: GO:0008150 ! biological process property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0040012 name: regulation of locomotion def: "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." [GOC:ems] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0040011 ! regulates locomotion relationship: RO:0002211 GO:0040011 ! regulates locomotion property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0040013 name: negative regulation of locomotion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "down regulation of locomotion" EXACT [] synonym: "down-regulation of locomotion" EXACT [] synonym: "downregulation of locomotion" EXACT [] synonym: "inhibition of locomotion" NARROW [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0040011 ! negatively regulates locomotion relationship: RO:0002212 GO:0040011 ! negatively regulates locomotion property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0040014 name: regulation of multicellular organism growth def: "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035264 ! regulates multicellular organism growth relationship: RO:0002211 GO:0035264 ! regulates multicellular organism growth property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0040015 name: negative regulation of multicellular organism growth def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "negative regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035264 ! negatively regulates multicellular organism growth relationship: RO:0002212 GO:0035264 ! negatively regulates multicellular organism growth property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0040016 name: embryonic cleavage def: "The first few specialized divisions of an activated animal egg." [GOC:clt, ISBN:0070524300] is_a: GO:0051301 ! cell division relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0009790 ! embryo development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0040017 name: positive regulation of locomotion def: "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "activation of locomotion" NARROW [] synonym: "stimulation of locomotion" NARROW [] synonym: "up regulation of locomotion" EXACT [] synonym: "up-regulation of locomotion" EXACT [] synonym: "upregulation of locomotion" EXACT [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0040011 ! positively regulates locomotion relationship: RO:0002213 GO:0040011 ! positively regulates locomotion property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0040018 name: positive regulation of multicellular organism growth def: "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "positive regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035264 ! positively regulates multicellular organism growth relationship: RO:0002213 GO:0035264 ! positively regulates multicellular organism growth property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0040019 name: positive regulation of embryonic development def: "Any process that activates or increases the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "activation of embryonic development" NARROW [] synonym: "stimulation of embryonic development" NARROW [] synonym: "up regulation of embryonic development" EXACT [] synonym: "up-regulation of embryonic development" EXACT [] synonym: "upregulation of embryonic development" EXACT [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009790 ! positively regulates embryo development relationship: RO:0002213 GO:0009790 ! positively regulates embryo development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0040020 name: regulation of meiotic nuclear division def: "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma] synonym: "regulation of meiosis" BROAD [GOC:vw] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0140013 ! regulates meiotic nuclear division relationship: RO:0002211 GO:0140013 ! regulates meiotic nuclear division [Term] id: GO:0040029 name: epigenetic regulation of gene expression def: "A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal." [PMID:10521337, PMID:11498582, PMID:22243696, PMID:34414474] subset: goslim_plant synonym: "regulation of gene expression, epigenetic" EXACT [] xref: Reactome:R-HSA-212165 "Epigenetic regulation of gene expression" xref: Reactome:R-HSA-8986944 "Transcriptional Regulation by MECP2" is_a: GO:0006338 ! chromatin remodeling is_a: GO:0010468 ! regulation of gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22201" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24794" xsd:anyURI [Term] id: GO:0040034 name: regulation of development, heterochronic def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:9442909] synonym: "developmental timing" RELATED [] synonym: "heterochronic regulation of development" EXACT [] synonym: "temporal regulation of development" EXACT [] is_a: GO:0050793 ! regulation of developmental process [Term] id: GO:0042044 name: fluid transport def: "The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport [Term] id: GO:0042045 name: epithelial fluid transport def: "The directed movement of fluid across epithelia." [GOC:jl, PMID:11390830] is_a: GO:0042044 ! fluid transport is_a: GO:0070633 ! transepithelial transport intersection_of: GO:0042044 ! fluid transport intersection_of: RO:0002342 UBERON:0000483 ! results in transport across epithelium [Term] id: GO:0042063 name: gliogenesis def: "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." [GOC:dgh, GOC:jid] synonym: "glial cell generation" EXACT systematic_synonym [] is_a: GO:0022008 ! neurogenesis intersection_of: GO:0008150 ! biological process intersection_of: RO:0002297 CL:0000125 ! results in formation of anatomical entity glial cell relationship: RO:0002297 CL:0000125 ! results in formation of anatomical entity glial cell [Term] id: GO:0042065 name: glial cell growth def: "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 CL:0000125 ! results in growth of glial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042063 ! gliogenesis relationship: RO:0002343 CL:0000125 ! results in growth of glial cell [Term] id: GO:0042069 name: regulation of catecholamine metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." [GOC:go_curators] synonym: "regulation of catecholamine metabolism" EXACT [] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006584 ! regulates catecholamine metabolic process relationship: RO:0002211 GO:0006584 ! regulates catecholamine metabolic process [Term] id: GO:0042073 name: intraciliary transport alt_id: GO:0035734 def: "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." [GOC:cilia, GOC:kmv, PMID:17981739, PMID:18180368, PMID:22869374] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "IFT" RELATED [] synonym: "intraflagellar transport" EXACT [] synonym: "intraflagellar transport involved in cilium organization" EXACT [] synonym: "intraflagellar transport involved in microtubule-based flagellum organisation" EXACT [] xref: Wikipedia:Intraflagellar_transport is_a: GO:0010970 ! transport along microtubule intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005929 ! occurs in cilium intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0032991 ! has primary input protein-containing complex relationship: BFO:0000066 GO:0005929 ! occurs in cilium relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0044782 ! cilium organization relationship: RO:0004009 GO:0032991 ! has primary input protein-containing complex property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0042074 name: cell migration involved in gastrulation def: "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." [GOC:jl, PMID:16099638] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0007369 ! gastrulation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007369 ! gastrulation [Term] id: GO:0042078 name: germ-line stem cell division alt_id: GO:0048131 def: "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jid, PMID:2279698] synonym: "germ-line stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000014 ! has primary input germ line stem cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0007281 ! germ cell development relationship: RO:0004009 CL:0000014 ! has primary input germ line stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0042098 name: T cell proliferation alt_id: GO:0042111 def: "The expansion of a T cell population by cell division. Follows T cell activation." [GOC:jl] synonym: "T lymphocyte proliferation" EXACT [] synonym: "T-cell proliferation" EXACT [] synonym: "T-lymphocyte proliferation" EXACT [] is_a: GO:0042110 ! T cell activation is_a: GO:0046651 ! lymphocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000084 ! acts on population of T cell relationship: RO:0012003 CL:0000084 ! acts on population of T cell [Term] id: GO:0042102 name: positive regulation of T cell proliferation def: "Any process that activates or increases the rate or extent of T cell proliferation." [GOC:ai] synonym: "activation of T cell proliferation" NARROW [] synonym: "positive regulation of T lymphocyte proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte proliferation" EXACT [] synonym: "stimulation of T cell proliferation" NARROW [] synonym: "up regulation of T cell proliferation" EXACT [] synonym: "up-regulation of T cell proliferation" EXACT [] synonym: "upregulation of T cell proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050671 ! positive regulation of lymphocyte proliferation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042098 ! positively regulates T cell proliferation relationship: RO:0002213 GO:0042098 ! positively regulates T cell proliferation [Term] id: GO:0042103 name: positive regulation of T cell homeostatic proliferation def: "Any process that activates or increases the rate or extent of resting T cell proliferation." [GOC:jl] synonym: "activation of T cell homeostatic proliferation" NARROW [] synonym: "positive regulation of resting T cell proliferation" EXACT [] synonym: "positive regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "positive regulation of T-cell homeostatic proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte homeostatic proliferation" EXACT [] synonym: "stimulation of T cell homeostatic proliferation" NARROW [] synonym: "up regulation of T cell homeostatic proliferation" EXACT [] synonym: "up-regulation of T cell homeostatic proliferation" EXACT [] synonym: "upregulation of T cell homeostatic proliferation" EXACT [] is_a: GO:0042102 ! positive regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001777 ! positively regulates T cell homeostatic proliferation relationship: RO:0002213 GO:0001777 ! positively regulates T cell homeostatic proliferation [Term] id: GO:0042110 name: T cell activation def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735149] synonym: "T lymphocyte activation" EXACT [] synonym: "T-cell activation" EXACT [] synonym: "T-lymphocyte activation" EXACT [] is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000084 ! has primary input T cell relationship: RO:0004009 CL:0000084 ! has primary input T cell [Term] id: GO:0042118 name: endothelial cell activation def: "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149, PMID:12851652, PMID:14581484] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000115 ! has primary input endothelial cell relationship: RO:0004009 CL:0000115 ! has primary input endothelial cell [Term] id: GO:0042127 name: regulation of cell population proliferation def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] synonym: "regulation of cell proliferation" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008283 ! regulates cell population proliferation relationship: RO:0002211 GO:0008283 ! regulates cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0042129 name: regulation of T cell proliferation def: "Any process that modulates the frequency, rate or extent of T cell proliferation." [GOC:jl] synonym: "regulation of T lymphocyte proliferation" EXACT [] synonym: "regulation of T-cell proliferation" EXACT [] synonym: "regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042098 ! regulates T cell proliferation relationship: RO:0002211 GO:0042098 ! regulates T cell proliferation [Term] id: GO:0042130 name: negative regulation of T cell proliferation def: "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." [GOC:jl] synonym: "down regulation of T cell proliferation" EXACT [] synonym: "down-regulation of T cell proliferation" EXACT [] synonym: "downregulation of T cell proliferation" EXACT [] synonym: "inhibition of T cell proliferation" NARROW [] synonym: "negative regulation of T lymphocyte proliferation" EXACT [] synonym: "negative regulation of T-cell proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050672 ! negative regulation of lymphocyte proliferation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042098 ! negatively regulates T cell proliferation relationship: RO:0002212 GO:0042098 ! negatively regulates T cell proliferation [Term] id: GO:0042175 name: nuclear outer membrane-endoplasmic reticulum membrane network def: "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." [GOC:bf, GOC:jl, GOC:mah, GOC:mcc, GOC:pr, GOC:vw] synonym: "NE-ER continuum" RELATED [] synonym: "NE-ER network" RELATED [] synonym: "nuclear envelope-endoplasmic reticulum continuum" RELATED [] synonym: "nuclear envelope-endoplasmic reticulum network" RELATED [GOC:mah] synonym: "nuclear envelope-ER network" RELATED [] synonym: "nuclear membrane-endoplasmic reticulum continuum" EXACT [GOC:mah] synonym: "nuclear membrane-ER network" EXACT [GOC:mah] is_a: GO:0016020 ! membrane relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0042176 name: regulation of protein catabolic process alt_id: GO:1903362 alt_id: GO:2000598 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators, GOC:jl] synonym: "regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein catabolic process" EXACT [] synonym: "regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "regulation of cyclin breakdown" NARROW [GOC:obol] synonym: "regulation of cyclin catabolic process" NARROW [] synonym: "regulation of cyclin catabolism" NARROW [GOC:obol] synonym: "regulation of cyclin degradation" NARROW [GOC:obol] synonym: "regulation of degradation of cyclin" NARROW [GOC:obol] synonym: "regulation of protein breakdown" EXACT [] synonym: "regulation of protein catabolism" EXACT [] synonym: "regulation of protein degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030163 ! regulates protein catabolic process relationship: RO:0002211 GO:0030163 ! regulates protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI created_by: kmv creation_date: 2014-08-21T15:05:45Z [Term] id: GO:0042177 name: negative regulation of protein catabolic process alt_id: GO:1903363 alt_id: GO:2000599 def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082] synonym: "down regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of protein catabolic process" EXACT [] synonym: "down-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein catabolic process" EXACT [] synonym: "downregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein catabolic process" EXACT [] synonym: "inhibition of cellular protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of protein catabolic process" NARROW [] synonym: "negative regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein catabolic process" EXACT [] synonym: "negative regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein breakdown" EXACT [] synonym: "negative regulation of protein catabolism" EXACT [] synonym: "negative regulation of protein degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030163 ! negatively regulates protein catabolic process relationship: RO:0002212 GO:0030163 ! negatively regulates protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0042180 name: ketone metabolic process def: "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:jl, ISBN:0787650153] subset: goslim_pir synonym: "ketone metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:17087 ! has primary input or output ketone relationship: RO:0004007 CHEBI:17087 ! has primary input or output ketone property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] id: GO:0042181 name: ketone biosynthetic process def: "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone anabolism" EXACT [] synonym: "ketone biosynthesis" EXACT [] synonym: "ketone formation" EXACT [] synonym: "ketone synthesis" EXACT [] is_a: GO:0042180 ! ketone metabolic process is_a: GO:0044283 ! small molecule biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:17087 ! has primary output ketone relationship: RO:0004008 CHEBI:17087 ! has primary output ketone [Term] id: GO:0042182 name: ketone catabolic process def: "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone breakdown" EXACT [] synonym: "ketone catabolism" EXACT [] synonym: "ketone degradation" EXACT [] is_a: GO:0042180 ! ketone metabolic process is_a: GO:0044282 ! small molecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:17087 ! has primary input ketone relationship: RO:0004009 CHEBI:17087 ! has primary input ketone [Term] id: GO:0042221 name: response to chemical def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant subset: goslim_plant_ribbon subset: goslim_yeast synonym: "response to chemical stimulus" EXACT [GOC:dos] synonym: "response to chemical substance" EXACT [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:24431 ! has primary input chemical entity relationship: RO:0004009 CHEBI:24431 ! has primary input chemical entity [Term] id: GO:0042254 name: ribosome biogenesis alt_id: GO:0007046 def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote subset: goslim_prokaryote_ribbon synonym: "ribosome biogenesis and assembly" EXACT [] is_a: GO:0022613 ! ribonucleoprotein complex biogenesis [Term] id: GO:0042255 name: ribosome assembly alt_id: GO:0042257 def: "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." [GOC:ma, PMID:30467428] subset: goslim_yeast synonym: "ribosomal subunit assembly" NARROW [GOC:mah, GOC:vw] is_a: GO:0140694 ! membraneless organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005840 ! results in assembly of ribosome relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0042254 ! ribosome biogenesis relationship: RO:0002588 GO:0005840 ! results in assembly of ribosome [Term] id: GO:0042303 name: molting cycle namespace: biological_process def: "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc." [GOC:jl, ISBN:0198506732] subset: goslim_drosophila subset: goslim_pir is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0042306 name: regulation of protein import into nucleus def: "Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus." [GOC:jl] synonym: "regulation of protein import into cell nucleus" EXACT [] synonym: "regulation of protein transport from cytoplasm to nucleus" EXACT [] synonym: "regulation of protein-nucleus import" EXACT [] is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0046822 ! regulation of nucleocytoplasmic transport is_a: GO:1900180 ! regulation of protein localization to nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006606 ! regulates protein import into nucleus relationship: RO:0002211 GO:0006606 ! regulates protein import into nucleus [Term] id: GO:0042307 name: positive regulation of protein import into nucleus def: "Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus." [GOC:jl] synonym: "activation of protein import into nucleus" NARROW [] synonym: "positive regulation of protein import into cell nucleus" EXACT [] synonym: "positive regulation of protein transport from cytoplasm to nucleus" EXACT [] synonym: "positive regulation of protein-nucleus import" EXACT [] synonym: "stimulation of protein import into nucleus" NARROW [] synonym: "up regulation of protein import into nucleus" EXACT [] synonym: "up-regulation of protein import into nucleus" EXACT [] synonym: "upregulation of protein import into nucleus" EXACT [] is_a: GO:0042306 ! regulation of protein import into nucleus is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport is_a: GO:0090316 ! positive regulation of intracellular protein transport is_a: GO:1900182 ! positive regulation of protein localization to nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006606 ! positively regulates protein import into nucleus relationship: RO:0002213 GO:0006606 ! positively regulates protein import into nucleus [Term] id: GO:0042308 name: negative regulation of protein import into nucleus def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus." [GOC:jl] synonym: "down regulation of protein import into nucleus" EXACT [] synonym: "down-regulation of protein import into nucleus" EXACT [] synonym: "downregulation of protein import into nucleus" EXACT [] synonym: "inhibition of protein import into nucleus" NARROW [] synonym: "negative regulation of protein import into cell nucleus" EXACT [] synonym: "negative regulation of protein transport from cytoplasm to nucleus" EXACT [] synonym: "negative regulation of protein-nucleus import" EXACT [] is_a: GO:0042306 ! regulation of protein import into nucleus is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport is_a: GO:0090317 ! negative regulation of intracellular protein transport is_a: GO:1900181 ! negative regulation of protein localization to nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006606 ! negatively regulates protein import into nucleus relationship: RO:0002212 GO:0006606 ! negatively regulates protein import into nucleus [Term] id: GO:0042391 name: regulation of membrane potential def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732] is_a: GO:0065008 ! regulation of biological quality relationship: has_part GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0042401 name: biogenic amine biosynthetic process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine anabolism" EXACT [] synonym: "biogenic amine biosynthesis" EXACT [] synonym: "biogenic amine formation" EXACT [] synonym: "biogenic amine synthesis" EXACT [] synonym: "cellular biogenic amine biosynthetic process" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009309 ! amine biosynthetic process [Term] id: GO:0042402 name: biogenic amine catabolic process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:go_curators, GOC:jl, ISBN:0198506732] synonym: "biogenic amine breakdown" EXACT [] synonym: "biogenic amine catabolism" EXACT [] synonym: "biogenic amine degradation" EXACT [] is_a: GO:0009310 ! amine catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] id: GO:0042415 name: norepinephrine metabolic process def: "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol metabolic process" EXACT [] synonym: "levarterenol metabolism" EXACT [] synonym: "noradrenaline metabolic process" EXACT [] synonym: "noradrenaline metabolism" EXACT [] synonym: "norepinephrine metabolism" EXACT [] is_a: GO:0006584 ! catecholamine metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:72587 ! has primary input or output (R)-noradrenaline(1+) relationship: RO:0004007 CHEBI:72587 ! has primary input or output (R)-noradrenaline(1+) [Term] id: GO:0042421 name: norepinephrine biosynthetic process def: "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol biosynthesis" EXACT [] synonym: "levarterenol biosynthetic process" EXACT [] synonym: "noradrenaline biosynthesis" EXACT [] synonym: "noradrenaline biosynthetic process" EXACT [] synonym: "norepinephrine anabolism" EXACT [] synonym: "norepinephrine biosynthesis" EXACT [] synonym: "norepinephrine formation" EXACT [] synonym: "norepinephrine synthesis" EXACT [] is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:0042423 ! catecholamine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:72587 ! has primary output (R)-noradrenaline(1+) relationship: RO:0004008 CHEBI:72587 ! has primary output (R)-noradrenaline(1+) [Term] id: GO:0042422 name: norepinephrine catabolic process def: "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol catabolic process" EXACT [] synonym: "levarterenol catabolism" EXACT [] synonym: "noradrenaline catabolic process" EXACT [] synonym: "noradrenaline catabolism" EXACT [] synonym: "norepinephrine breakdown" EXACT [] synonym: "norepinephrine catabolism" EXACT [] synonym: "norepinephrine degradation" EXACT [] xref: Wikipedia:Norepinephrine#Degradation is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:0042424 ! catecholamine catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) relationship: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0042423 name: catecholamine biosynthetic process def: "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine anabolism" EXACT [] synonym: "catecholamine biosynthesis" EXACT [] synonym: "catecholamine formation" EXACT [] synonym: "catecholamine synthesis" EXACT [] xref: Reactome:R-HSA-209905 "Catecholamine biosynthesis" xref: Wikipedia:Catecholamines is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0009713 ! catechol-containing compound biosynthetic process is_a: GO:0042401 ! biogenic amine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33567 ! has primary output catecholamine relationship: RO:0004008 CHEBI:33567 ! has primary output catecholamine [Term] id: GO:0042424 name: catecholamine catabolic process def: "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine breakdown" EXACT [] synonym: "catecholamine catabolism" EXACT [] synonym: "catecholamine degradation" EXACT [] is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0019614 ! catechol-containing compound catabolic process is_a: GO:0042402 ! biogenic amine catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0004009 CHEBI:33567 ! has primary input catecholamine [Term] id: GO:0042427 name: serotonin biosynthetic process def: "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin anabolism" EXACT [] synonym: "serotonin biosynthesis" EXACT [] synonym: "serotonin formation" EXACT [] synonym: "serotonin synthesis" EXACT [] xref: Wikipedia:Serotonin is_a: GO:0042428 ! serotonin metabolic process is_a: GO:0042435 ! indole-containing compound biosynthetic process is_a: GO:0046189 ! phenol-containing compound biosynthetic process is_a: GO:1901162 ! primary amino compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:350546 ! has primary output serotonin(1+) relationship: RO:0004008 CHEBI:350546 ! has primary output serotonin(1+) [Term] id: GO:0042428 name: serotonin metabolic process def: "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin metabolism" EXACT [] is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0042430 ! indole-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:350546 ! has primary input or output serotonin(1+) relationship: RO:0004007 CHEBI:350546 ! has primary input or output serotonin(1+) property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30537" xsd:anyURI [Term] id: GO:0042429 name: serotonin catabolic process def: "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin breakdown" EXACT [] synonym: "serotonin catabolism" EXACT [] synonym: "serotonin degradation" EXACT [] xref: Reactome:R-HSA-380612 "Metabolism of serotonin" is_a: GO:0019336 ! phenol-containing compound catabolic process is_a: GO:0042428 ! serotonin metabolic process is_a: GO:0042436 ! indole-containing compound catabolic process is_a: GO:1901161 ! primary amino compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) relationship: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0042430 name: indole-containing compound metabolic process alt_id: GO:0042434 def: "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl, GOC:mah] synonym: "indole and derivative metabolic process" EXACT [] synonym: "indole and derivative metabolism" EXACT [] synonym: "indole derivative metabolic process" NARROW [] synonym: "indole derivative metabolism" NARROW [] synonym: "indole-containing compound metabolism" EXACT [] synonym: "ketole metabolic process" EXACT [] synonym: "ketole metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:24828 ! has primary input or output indoles relationship: RO:0004007 CHEBI:24828 ! has primary input or output indoles [Term] id: GO:0042435 name: indole-containing compound biosynthetic process def: "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative biosynthesis" EXACT [] synonym: "indole derivative biosynthetic process" EXACT [] synonym: "indole-containing compound anabolism" EXACT [] synonym: "indole-containing compound biosynthesis" EXACT [] synonym: "indole-containing compound formation" EXACT [] synonym: "indole-containing compound synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0042430 ! indole-containing compound metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:24828 ! has primary output indoles relationship: RO:0004008 CHEBI:24828 ! has primary output indoles [Term] id: GO:0042436 name: indole-containing compound catabolic process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative catabolic process" EXACT [] synonym: "indole derivative catabolism" EXACT [] synonym: "indole-containing compound breakdown" EXACT [] synonym: "indole-containing compound catabolism" EXACT [] synonym: "indole-containing compound degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0042430 ! indole-containing compound metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:24828 ! has primary input indoles relationship: RO:0004009 CHEBI:24828 ! has primary input indoles [Term] id: GO:0042461 name: photoreceptor cell development alt_id: GO:0046531 def: "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." [GOC:go_curators] synonym: "photoreceptor morphogenesis" EXACT [] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000210 ! results in development of photoreceptor cell relationship: part_of GO:0046530 ! photoreceptor cell differentiation relationship: RO:0002296 CL:0000210 ! results in development of photoreceptor cell [Term] id: GO:0042462 name: eye photoreceptor cell development def: "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." [GOC:jl, ISBN:0192800981] is_a: GO:0042461 ! photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000287 ! results in development of eye photoreceptor cell relationship: part_of GO:0001754 ! eye photoreceptor cell differentiation relationship: RO:0002296 CL:0000287 ! results in development of eye photoreceptor cell [Term] id: GO:0042471 name: ear morphogenesis def: "The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GOC:jl, ISBN:0192801023] synonym: "hearing organ morphogenesis" EXACT [] is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001690 ! results in morphogenesis of ear relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043583 ! ear development relationship: RO:0002298 UBERON:0001690 ! results in morphogenesis of ear [Term] id: GO:0042472 name: inner ear morphogenesis def: "The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively." [GOC:jl, ISBN:0192801023] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001846 ! results in morphogenesis of internal ear relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0042471 ! ear morphogenesis relationship: part_of GO:0048839 ! inner ear development relationship: RO:0002298 UBERON:0001846 ! results in morphogenesis of internal ear [Term] id: GO:0042473 name: outer ear morphogenesis def: "The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull." [GOC:jl, ISBN:0192801023] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001691 ! results in morphogenesis of external ear relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0042471 ! ear morphogenesis relationship: RO:0002298 UBERON:0001691 ! results in morphogenesis of external ear [Term] id: GO:0042474 name: middle ear morphogenesis def: "The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)." [GOC:jl, ISBN:0192801023] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001756 ! results in morphogenesis of middle ear relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0042471 ! ear morphogenesis relationship: RO:0002298 UBERON:0001756 ! results in morphogenesis of middle ear [Term] id: GO:0042475 name: odontogenesis of dentin-containing tooth def: "The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel." [GOC:cjm, GOC:mah, GOC:mtg_sensu, PMID:10333884, PMID:15355794] comment: Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales. synonym: "odontogenesis of dentine-containing teeth" EXACT [] synonym: "odontogenesis of dentine-containing tooth" EXACT [GOC:mah] synonym: "odontogeny" BROAD [] synonym: "odontosis" BROAD [] synonym: "tooth development" BROAD [] is_a: GO:0042476 ! odontogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001091 ! results in morphogenesis of calcareous tooth relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002298 UBERON:0001091 ! results in morphogenesis of calcareous tooth property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042476 name: odontogenesis alt_id: GO:0042477 def: "The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food." [GOC:jl, GOC:mah] synonym: "odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "odontogeny" EXACT [] synonym: "odontosis" EXACT [] synonym: "tooth development" RELATED [] synonym: "tooth morphogenesis" EXACT [] xref: Wikipedia:Odontogenesis is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003913 ! results in morphogenesis of tooth-like structure relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002298 UBERON:0003913 ! results in morphogenesis of tooth-like structure property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042478 name: regulation of eye photoreceptor cell development def: "Any process that modulates the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "regulation of eye photoreceptor development" EXACT [] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042462 ! regulates eye photoreceptor cell development relationship: RO:0002211 GO:0042462 ! regulates eye photoreceptor cell development [Term] id: GO:0042479 name: positive regulation of eye photoreceptor cell development def: "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "activation of eye photoreceptor cell development" NARROW [] synonym: "positive regulation of eye photoreceptor development" EXACT [] synonym: "stimulation of eye photoreceptor cell development" NARROW [] synonym: "up regulation of eye photoreceptor cell development" EXACT [] synonym: "up-regulation of eye photoreceptor cell development" EXACT [] synonym: "upregulation of eye photoreceptor cell development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042462 ! positively regulates eye photoreceptor cell development relationship: RO:0002213 GO:0042462 ! positively regulates eye photoreceptor cell development [Term] id: GO:0042480 name: negative regulation of eye photoreceptor cell development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "down regulation of eye photoreceptor cell development" EXACT [] synonym: "down-regulation of eye photoreceptor cell development" EXACT [] synonym: "downregulation of eye photoreceptor cell development" EXACT [] synonym: "inhibition of eye photoreceptor cell development" NARROW [] synonym: "negative regulation of eye photoreceptor development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042462 ! negatively regulates eye photoreceptor cell development relationship: RO:0002212 GO:0042462 ! negatively regulates eye photoreceptor cell development [Term] id: GO:0042481 name: regulation of odontogenesis alt_id: GO:0042484 def: "Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] synonym: "regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "regulation of tooth development" EXACT [] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042476 ! regulates odontogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0042476 ! regulates odontogenesis property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042482 name: positive regulation of odontogenesis alt_id: GO:0042485 def: "Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] synonym: "activation of odontogenesis" NARROW [] synonym: "positive regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "positive regulation of tooth development" EXACT [] synonym: "stimulation of odontogenesis" NARROW [] synonym: "up regulation of odontogenesis" EXACT [] synonym: "up-regulation of odontogenesis" EXACT [] synonym: "upregulation of odontogenesis" EXACT [] is_a: GO:0042481 ! regulation of odontogenesis is_a: GO:0110110 ! positive regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042476 ! positively regulates odontogenesis relationship: RO:0002213 GO:0042476 ! positively regulates odontogenesis property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042483 name: negative regulation of odontogenesis alt_id: GO:0042486 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] synonym: "down regulation of odontogenesis" EXACT [] synonym: "down-regulation of odontogenesis" EXACT [] synonym: "downregulation of odontogenesis" EXACT [] synonym: "inhibition of odontogenesis" NARROW [] synonym: "negative regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "negative regulation of tooth development" EXACT [] is_a: GO:0042481 ! regulation of odontogenesis is_a: GO:0110111 ! negative regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042476 ! negatively regulates odontogenesis relationship: RO:0002212 GO:0042476 ! negatively regulates odontogenesis property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042487 name: regulation of odontogenesis of dentin-containing tooth def: "Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates." [GOC:jl, GOC:mtg_sensu, PMID:15355794] synonym: "regulation of odontogenesis of dentine-containing teeth" EXACT [] synonym: "regulation of odontogenesis of dentine-containing tooth" EXACT [GOC:mah] is_a: GO:0042481 ! regulation of odontogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042475 ! regulates odontogenesis of dentin-containing tooth relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0042475 ! regulates odontogenesis of dentin-containing tooth property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042488 name: positive regulation of odontogenesis of dentin-containing tooth def: "Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates." [GOC:jl, PMID:15355794] synonym: "activation of odontogenesis" BROAD [] synonym: "positive regulation of odontogenesis of dentine-containing teeth" EXACT [] synonym: "positive regulation of odontogenesis of dentine-containing tooth" RELATED [] synonym: "stimulation of odontogenesis" BROAD [] synonym: "up regulation of odontogenesis" BROAD [] synonym: "up-regulation of odontogenesis" BROAD [] synonym: "upregulation of odontogenesis" BROAD [] is_a: GO:0042482 ! positive regulation of odontogenesis is_a: GO:0042487 ! regulation of odontogenesis of dentin-containing tooth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042475 ! positively regulates odontogenesis of dentin-containing tooth relationship: RO:0002213 GO:0042475 ! positively regulates odontogenesis of dentin-containing tooth property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042489 name: negative regulation of odontogenesis of dentin-containing tooth def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx." [GOC:jl, GOC:mtg_sensu, PMID:15355794] synonym: "down regulation of odontogenesis" BROAD [] synonym: "down-regulation of odontogenesis" BROAD [] synonym: "downregulation of odontogenesis" BROAD [] synonym: "inhibition of odontogenesis" BROAD [] synonym: "negative regulation of odontogenesis" BROAD [] synonym: "negative regulation of odontogenesis of dentine-containing teeth" EXACT [] synonym: "negative regulation of odontogenesis of dentine-containing tooth" RELATED [] is_a: GO:0042483 ! negative regulation of odontogenesis is_a: GO:0042487 ! regulation of odontogenesis of dentin-containing tooth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042475 ! negatively regulates odontogenesis of dentin-containing tooth relationship: RO:0002212 GO:0042475 ! negatively regulates odontogenesis of dentin-containing tooth property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042551 name: neuron maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." [GOC:dph, GOC:jl] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000540 ! results in maturation of neuron relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048666 ! neuron development relationship: RO:0002299 CL:0000540 ! results in maturation of neuron [Term] id: GO:0042552 name: myelination def: "The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GOC:dgh, GOC:mah] synonym: "myelinogenesis" RELATED [GOC:cjm, HP:0003429] xref: Wikipedia:Myelin is_a: GO:0008366 ! axon ensheathment [Term] id: GO:0042588 name: zymogen granule def: "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." [GOC:jl, ISBN:0198506732] is_a: GO:0030141 ! secretory granule property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0042589 name: zymogen granule membrane def: "The lipid bilayer surrounding a zymogen granule." [GOC:jl] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0042588 ! zymogen granule relationship: bounding_layer_of GO:0042588 ! zymogen granule relationship: part_of GO:0042588 ! zymogen granule property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0042592 name: homeostatic process alt_id: GO:0032844 alt_id: GO:0032845 alt_id: GO:0032846 def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse synonym: "activation of homeostatic process" NARROW [] synonym: "homeostasis" EXACT [] synonym: "inhibition of homeostatic process" NARROW [] synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological process [Term] id: GO:0042593 name: glucose homeostasis def: "Any process involved in the maintenance of an internal steady state of glucose within an organism or cell." [GOC:go_curators] is_a: GO:0033500 ! carbohydrate homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:4167 ! regulates levels of D-glucopyranose relationship: RO:0002332 CHEBI:4167 ! regulates levels of D-glucopyranose [Term] id: GO:0042611 name: MHC protein complex def: "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0781735149, PMID:15928678, PMID:16153240] subset: goslim_pir is_a: GO:0098797 ! plasma membrane protein complex [Term] id: GO:0042613 name: MHC class II protein complex def: "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0120781859, PMID:15928678] is_a: GO:0042611 ! MHC protein complex [Term] id: GO:0042633 name: hair cycle namespace: biological_process def: "The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body." [GOC:go_curators, PMID:12230507] is_a: GO:0042303 ! molting cycle [Term] id: GO:0042637 name: catagen namespace: biological_process def: "The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced." [PMID:12535193] comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). subset: gocheck_do_not_annotate synonym: "hair regression" NARROW [] is_a: GO:0044851 ! hair cycle phase relationship: part_of GO:0048820 ! hair follicle maturation [Term] id: GO:0042638 name: exogen namespace: biological_process def: "The shedding phase of the hair cycle." [PMID:12230507] comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). subset: gocheck_do_not_annotate synonym: "hair shedding" NARROW [] is_a: GO:0044851 ! hair cycle phase relationship: part_of GO:0048820 ! hair follicle maturation [Term] id: GO:0042640 name: anagen namespace: biological_process def: "The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair." [PMID:12230507] comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). subset: gocheck_do_not_annotate synonym: "hair growth" RELATED [] is_a: GO:0044851 ! hair cycle phase relationship: part_of GO:0048820 ! hair follicle maturation [Term] id: GO:0042641 name: actomyosin def: "Any complex of actin, myosin, and accessory proteins." [GOC:go_curators] synonym: "actomyosin complex" EXACT [] synonym: "actomyosin structure" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0042670 name: retinal cone cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." [GOC:go_curators] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000573 ! results in acquisition of features of retinal cone cell relationship: RO:0002315 CL:0000573 ! results in acquisition of features of retinal cone cell [Term] id: GO:0042692 name: muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." [CL:0000187, GOC:go_curators] synonym: "myogenesis" RELATED [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000187 ! results in acquisition of features of muscle cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0061061 ! muscle structure development relationship: RO:0002315 CL:0000187 ! results in acquisition of features of muscle cell [Term] id: GO:0042698 name: ovulation cycle def: "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [ISBN:0721662544] is_a: GO:0048511 ! rhythmic process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0042702 name: uterine wall growth def: "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels." [GOC:jl] is_a: GO:0022602 ! ovulation cycle process is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: RO:0002343 UBERON:0000459 ! results in growth of uterine wall relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001553 ! luteinization relationship: RO:0002343 UBERON:0000459 ! results in growth of uterine wall [Term] id: GO:0042713 name: sperm ejaculation def: "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." [GOC:jl, PMID:26385403] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007320 ! insemination [Term] id: GO:0042762 name: regulation of sulfur metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators] synonym: "regulation of sulfur metabolism" EXACT [] synonym: "regulation of sulphur metabolic process" EXACT [] synonym: "regulation of sulphur metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006790 ! regulates sulfur compound metabolic process relationship: RO:0002211 GO:0006790 ! regulates sulfur compound metabolic process [Term] id: GO:0042886 name: amide transport def: "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] subset: goslim_pir is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:32988 ! has primary input amide relationship: RO:0004009 CHEBI:32988 ! has primary input amide [Term] id: GO:0042887 name: amide transmembrane transporter activity def: "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732] synonym: "amine/amide/polyamine channel activity" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:32988 ! has primary input amide relationship: part_of GO:0042886 ! amide transport relationship: RO:0004009 CHEBI:32988 ! has primary input amide [Term] id: GO:0042981 name: regulation of apoptotic process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym: "apoptosis regulator activity" RELATED [] synonym: "regulation of apoptosis" NARROW [] xref: Reactome:R-HSA-169911 "Regulation of Apoptosis" xref: Reactome:R-HSA-5633008 "TP53 Regulates Transcription of Cell Death Genes" is_a: GO:0043067 ! regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006915 ! regulates apoptotic process relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: RO:0002211 GO:0006915 ! regulates apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0042995 name: cell projection def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, PMID:16318917] subset: goslim_agr subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_prokaryote subset: goslim_prokaryote_ribbon synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of CL:0000000 ! cell [Term] id: GO:0042996 name: regulation of Golgi to plasma membrane protein transport def: "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] is_a: GO:0051223 ! regulation of protein transport is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903076 ! regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043001 ! regulates Golgi to plasma membrane protein transport relationship: RO:0002211 GO:0043001 ! regulates Golgi to plasma membrane protein transport [Term] id: GO:0042997 name: negative regulation of Golgi to plasma membrane protein transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "down regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "down-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "downregulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "inhibition of Golgi to plasma membrane protein transport" NARROW [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043001 ! negatively regulates Golgi to plasma membrane protein transport relationship: RO:0002212 GO:0043001 ! negatively regulates Golgi to plasma membrane protein transport [Term] id: GO:0042998 name: positive regulation of Golgi to plasma membrane protein transport def: "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "activation of Golgi to plasma membrane protein transport" NARROW [] synonym: "stimulation of Golgi to plasma membrane protein transport" NARROW [] synonym: "up regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "up-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "upregulation of Golgi to plasma membrane protein transport" EXACT [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043001 ! positively regulates Golgi to plasma membrane protein transport relationship: RO:0002213 GO:0043001 ! positively regulates Golgi to plasma membrane protein transport [Term] id: GO:0043001 name: Golgi to plasma membrane protein transport def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." [ISBN:0716731363] is_a: GO:0006893 ! Golgi to plasma membrane transport is_a: GO:0015031 ! protein transport is_a: GO:0061951 ! establishment of protein localization to plasma membrane is_a: GO:0072659 ! protein localization to plasma membrane intersection_of: GO:0015031 ! protein transport intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane intersection_of: RO:0002608 GO:0031982 ! process has causal agent vesicle [Term] id: GO:0043005 name: neuron projection def: "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:jl, PMID:3077060] subset: goslim_pir synonym: "nerve fiber" RELATED [GOC:dph] synonym: "neurite" NARROW [] synonym: "neuron process" EXACT [] synonym: "neuron protrusion" EXACT [NIF_Subcellular:sao250931889] synonym: "neuronal cell projection" EXACT [] xref: NIF_Subcellular:sao867568886 is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000540 ! neuron relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000540 ! neuron [Term] id: GO:0043009 name: chordate embryonic development def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." [GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: in_taxon NCBITaxon:7711 ! Chordata [Term] id: GO:0043010 name: camera-type eye development alt_id: GO:0001747 alt_id: GO:0031075 def: "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000019 ! results in development of camera-type eye relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0000019 ! results in development of camera-type eye [Term] id: GO:0043025 name: neuronal cell body def: "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." [GOC:go_curators] comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. subset: goslim_pir synonym: "neuron cell body" EXACT [] synonym: "neuronal cell soma" EXACT [] xref: NIF_Subcellular:sao1044911821 xref: Wikipedia:Soma_(biology) is_a: GO:0044297 ! cell body intersection_of: GO:0044297 ! cell body intersection_of: part_of CL:0000540 ! neuron relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0036477 ! somatodendritic compartment [Term] id: GO:0043029 name: T cell homeostasis def: "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:mgi_curators, ISBN:0781735149] comment: Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus. synonym: "T lymphocyte homeostasis" EXACT [] synonym: "T-cell homeostasis" EXACT [] synonym: "T-lymphocyte homeostasis" EXACT [] is_a: GO:0002260 ! lymphocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000084 ! acts on population of T cell relationship: RO:0012003 CL:0000084 ! acts on population of T cell [Term] id: GO:0043038 name: amino acid activation def: "The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule." [GOC:jl] is_a: GO:0006520 ! amino acid metabolic process [Term] id: GO:0043039 name: tRNA aminoacylation def: "The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules." [GOC:ma, GOC:mah] synonym: "amino acid activation" RELATED [] synonym: "aminoacyl-tRNA biosynthesis" EXACT [GOC:mah] synonym: "aminoacyl-tRNA biosynthetic process" EXACT [GOC:mah] synonym: "tRNA charging" EXACT [] is_a: GO:0006399 ! tRNA metabolic process is_a: GO:0043038 ! amino acid activation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15375" xsd:anyURI [Term] id: GO:0043043 name: peptide biosynthetic process def: "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." [GOC:dph, GOC:jl] synonym: "peptide anabolism" EXACT [] synonym: "peptide biosynthesis" EXACT [] synonym: "peptide formation" EXACT [] synonym: "peptide synthesis" EXACT [] xref: Reactome:R-HSA-9037628 "Rhesus blood group biosynthesis" is_a: GO:0006518 ! peptide metabolic process is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:60466 ! has primary output peptide zwitterion relationship: RO:0004008 CHEBI:60466 ! has primary output peptide zwitterion [Term] id: GO:0043049 name: otic placode formation def: "The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain." [GOC:go_curators, PMID:12668634] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003069 ! results in formation of anatomical entity otic placode relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030916 ! otic vesicle formation relationship: RO:0002297 UBERON:0003069 ! results in formation of anatomical entity otic placode [Term] id: GO:0043062 name: extracellular structure organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir subset: goslim_prokaryote synonym: "extracellular structure organisation" EXACT [] synonym: "extracellular structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005576 ! results in organization of extracellular region relationship: RO:0002592 GO:0005576 ! results in organization of extracellular region [Term] id: GO:0043065 name: positive regulation of apoptotic process def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. subset: goslim_chembl synonym: "activation of apoptosis" NARROW [] synonym: "positive regulation of apoptosis" NARROW [] synonym: "pro-apoptosis" RELATED [] synonym: "stimulation of apoptosis" NARROW [] synonym: "up regulation of apoptosis" EXACT [] synonym: "up-regulation of apoptosis" EXACT [] synonym: "upregulation of apoptosis" EXACT [] xref: Reactome:R-HSA-193648 "NRAGE signals death through JNK" xref: Reactome:R-HSA-205043 "NRIF signals cell death from the nucleus" is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043068 ! positive regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006915 ! positively regulates apoptotic process relationship: RO:0002213 GO:0006915 ! positively regulates apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0043066 name: negative regulation of apoptotic process alt_id: GO:0006916 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym: "anti-apoptosis" EXACT [] synonym: "apoptosis inhibitor activity" RELATED [] synonym: "down regulation of apoptosis" EXACT [] synonym: "down-regulation of apoptosis" EXACT [] synonym: "downregulation of apoptosis" EXACT [] synonym: "inhibition of apoptosis" NARROW [] synonym: "negative regulation of apoptosis" NARROW [] synonym: "pro-survival" RELATED [] xref: Reactome:R-HSA-193639 "p75NTR signals via NF-kB" xref: Reactome:R-HSA-211728 "Regulation of PAK-2p34 activity by PS-GAP/RHG10" xref: Reactome:R-HSA-211733 "Regulation of activated PAK-2p34 by proteasome mediated degradation" is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043069 ! negative regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006915 ! negatively regulates apoptotic process relationship: RO:0002212 GO:0006915 ! negatively regulates apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0043067 name: regulation of programmed cell death alt_id: GO:0043070 def: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "regulation of non-apoptotic programmed cell death" NARROW [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0012501 ! regulates programmed cell death relationship: RO:0002211 GO:0012501 ! regulates programmed cell death [Term] id: GO:0043068 name: positive regulation of programmed cell death alt_id: GO:0043071 def: "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "activation of programmed cell death" NARROW [] synonym: "positive regulation of non-apoptotic programmed cell death" NARROW [] synonym: "stimulation of programmed cell death" NARROW [] synonym: "up regulation of programmed cell death" EXACT [] synonym: "up-regulation of programmed cell death" EXACT [] synonym: "upregulation of programmed cell death" EXACT [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0012501 ! positively regulates programmed cell death relationship: RO:0002213 GO:0012501 ! positively regulates programmed cell death [Term] id: GO:0043069 name: negative regulation of programmed cell death alt_id: GO:0043072 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "down regulation of programmed cell death" EXACT [] synonym: "down-regulation of programmed cell death" EXACT [] synonym: "downregulation of programmed cell death" EXACT [] synonym: "inhibition of programmed cell death" NARROW [] synonym: "negative regulation of non-apoptotic programmed cell death" NARROW [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0012501 ! negatively regulates programmed cell death relationship: RO:0002212 GO:0012501 ! negatively regulates programmed cell death [Term] id: GO:0043073 name: germ cell nucleus def: "The nucleus of a germ cell, a reproductive cell in multicellular organisms." [CL:0000586, GOC:go_curators] synonym: "germ-cell nucleus" EXACT [] is_a: GO:0005634 ! nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000586 ! germ cell relationship: part_of CL:0000586 ! germ cell [Term] id: GO:0043083 name: synaptic cleft def: "The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released." [GOC:jl, PMID:30784960] subset: goslim_synapse xref: NIF_Subcellular:sao243541954 is_a: GO:0005576 ! extracellular region relationship: adjacent_to GO:0045202 ! synapse [Term] id: GO:0043085 name: positive regulation of catalytic activity alt_id: GO:0048554 def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: gocheck_obsoletion_candidate subset: goslim_chembl synonym: "activation of enzyme activity" NARROW [] synonym: "activation of metalloenzyme activity" NARROW [] synonym: "positive regulation of enzyme activity" EXACT [GOC:tb] synonym: "positive regulation of metalloenzyme activity" NARROW [] synonym: "stimulation of enzyme activity" NARROW [] synonym: "stimulation of metalloenzyme activity" NARROW [] synonym: "up regulation of enzyme activity" EXACT [] synonym: "up regulation of metalloenzyme activity" NARROW [] synonym: "up-regulation of enzyme activity" EXACT [] synonym: "up-regulation of metalloenzyme activity" NARROW [] synonym: "upregulation of enzyme activity" EXACT [] synonym: "upregulation of metalloenzyme activity" NARROW [] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003824 ! positively regulates catalytic activity relationship: RO:0002213 GO:0003824 ! positively regulates catalytic activity [Term] id: GO:0043086 name: negative regulation of catalytic activity alt_id: GO:0048553 def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: gocheck_obsoletion_candidate synonym: "down regulation of enzyme activity" EXACT [] synonym: "down regulation of metalloenzyme activity" NARROW [] synonym: "down-regulation of enzyme activity" EXACT [] synonym: "down-regulation of metalloenzyme activity" EXACT [] synonym: "downregulation of enzyme activity" EXACT [] synonym: "downregulation of metalloenzyme activity" NARROW [] synonym: "inhibition of enzyme activity" NARROW [] synonym: "inhibition of metalloenzyme activity" NARROW [] synonym: "negative regulation of enzyme activity" EXACT [GOC:tb] synonym: "negative regulation of metalloenzyme activity" NARROW [] is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003824 ! negatively regulates catalytic activity relationship: RO:0002212 GO:0003824 ! negatively regulates catalytic activity [Term] id: GO:0043133 name: hindgut contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, GOC:mtg_muscle, UBERON:0001046] is_a: GO:0006939 ! smooth muscle contraction is_a: GO:0022600 ! digestive system process intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: BFO:0000066 UBERON:0001046 ! occurs in hindgut relationship: BFO:0000066 UBERON:0001046 ! occurs in hindgut property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0043134 name: regulation of hindgut contraction def: "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, UBERON:0001046] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044058 ! regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043133 ! regulates hindgut contraction relationship: RO:0002211 GO:0043133 ! regulates hindgut contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0043143 name: regulation of translation by machinery localization def: "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." [GOC:jl] synonym: "establishment and maintenance of translational machinery localization" EXACT [] synonym: "establishment and maintenance of translational protein localization" EXACT [] synonym: "regulation of translation by machinery localisation" EXACT [GOC:mah] synonym: "translational machinery localization" EXACT [GOC:dph, GOC:tb] synonym: "translational protein localization" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: part_of GO:0006412 ! translation relationship: part_of GO:0006412 ! translation [Term] id: GO:0043170 name: macromolecule metabolic process alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33694 ! has primary input or output biomacromolecule relationship: RO:0004007 CHEBI:33694 ! has primary input or output biomacromolecule property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043171 name: peptide catabolic process def: "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:jl] synonym: "peptide breakdown" EXACT [] synonym: "peptide catabolism" EXACT [] synonym: "peptide degradation" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion relationship: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion [Term] id: GO:0043200 name: response to amino acid alt_id: GO:0010237 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:ef, GOC:mlg] synonym: "response to amino acid stimulus" EXACT [GOC:dos] is_a: GO:0001101 ! response to acid chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion relationship: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion [Term] id: GO:0043207 name: response to external biotic stimulus def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:go_curators] is_a: GO:0009605 ! response to external stimulus is_a: GO:0009607 ! response to biotic stimulus [Term] id: GO:0043209 name: myelin sheath def: "An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system." [GOC:cjm, GOC:jl, NIF_Subcellular:sao593830697, Wikipedia:Myelin] synonym: "astrocyte sheath" NARROW [NIF_Subcellular:nlx_subcell_20090204] synonym: "oligodendrocyte myelin sheath" NARROW [NIF_Subcellular:sao1279474730] synonym: "Schwann cell myelin sheath" NARROW [] xref: FMA:62983 xref: NIF_Subcellular:sao593830697 xref: Wikipedia:Myelin is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000125 ! glial cell [Term] id: GO:0043226 name: organelle def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_chembl subset: goslim_generic subset: goslim_pir subset: goslim_prokaryote subset: goslim_prokaryote_ribbon xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical structure [Term] id: GO:0043227 name: membrane-bounded organelle def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] subset: gocheck_do_not_annotate synonym: "membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao414196390 is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: has_part GO:0016020 ! membrane disjoint_from: GO:0043228 ! membraneless organelle relationship: has_part GO:0016020 ! membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28153" xsd:anyURI [Term] id: GO:0043228 name: membraneless organelle def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_mouse synonym: "biological condensate" RELATED [] synonym: "membrane-less organelle" EXACT [] synonym: "non-membrane-bounded organelle" EXACT [] synonym: "non-membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao1456184038 is_a: GO:0043226 ! organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21881" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28153" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29106" xsd:anyURI [Term] id: GO:0043229 name: intracellular organelle def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_pir is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure disjoint_from: GO:0043230 ! extracellular organelle relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005622 ! intracellular anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28153" xsd:anyURI [Term] id: GO:0043230 name: extracellular organelle def: "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." [GOC:jl, PMID:9914479] subset: goslim_pir is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: part_of GO:0005576 ! extracellular region relationship: part_of GO:0005576 ! extracellular region [Term] id: GO:0043231 name: intracellular membrane-bounded organelle def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "intracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043232 name: intracellular membraneless organelle def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "intracellular non-membrane-bounded organelle" EXACT [] synonym: "intracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! membraneless organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043228 ! membraneless organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29106" xsd:anyURI [Term] id: GO:0043233 name: organelle lumen def: "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." [GOC:jl, GOC:mah] subset: goslim_mouse is_a: GO:0031974 ! membrane-enclosed lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0043226 ! organelle relationship: part_of GO:0043226 ! organelle [Term] id: GO:0043242 name: negative regulation of protein-containing complex disassembly def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "down regulation of protein complex disassembly" EXACT [] synonym: "down-regulation of protein complex disassembly" EXACT [] synonym: "downregulation of protein complex disassembly" EXACT [] synonym: "inhibition of protein complex disassembly" NARROW [] synonym: "negative regulation of protein complex disassembly" RELATED [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032984 ! negatively regulates protein-containing complex disassembly relationship: RO:0002212 GO:0032984 ! negatively regulates protein-containing complex disassembly [Term] id: GO:0043243 name: positive regulation of protein-containing complex disassembly def: "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "activation of protein complex disassembly" NARROW [] synonym: "positive regulation of protein complex disassembly" RELATED [] synonym: "stimulation of protein complex disassembly" NARROW [] synonym: "up regulation of protein complex disassembly" EXACT [] synonym: "up-regulation of protein complex disassembly" EXACT [] synonym: "upregulation of protein complex disassembly" EXACT [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032984 ! positively regulates protein-containing complex disassembly relationship: RO:0002213 GO:0032984 ! positively regulates protein-containing complex disassembly [Term] id: GO:0043244 name: regulation of protein-containing complex disassembly def: "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "regulation of protein complex disassembly" RELATED [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032984 ! regulates protein-containing complex disassembly relationship: RO:0002211 GO:0032984 ! regulates protein-containing complex disassembly [Term] id: GO:0043249 name: erythrocyte maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." [GOC:devbiol, GOC:jl] synonym: "RBC maturation" EXACT [CL:0000232] synonym: "red blood cell maturation" EXACT [CL:0000232] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000232 ! results in maturation of erythrocyte relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048821 ! erythrocyte development relationship: RO:0002299 CL:0000232 ! results in maturation of erythrocyte [Term] id: GO:0043254 name: regulation of protein-containing complex assembly def: "Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl] synonym: "regulation of protein complex assembly" RELATED [] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0065003 ! regulates protein-containing complex assembly relationship: RO:0002211 GO:0065003 ! regulates protein-containing complex assembly [Term] id: GO:0043255 name: regulation of carbohydrate biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." [GOC:jl] synonym: "regulation of carbohydrate anabolism" EXACT [] synonym: "regulation of carbohydrate biosynthesis" EXACT [] synonym: "regulation of carbohydrate formation" EXACT [] synonym: "regulation of carbohydrate synthesis" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016051 ! regulates carbohydrate biosynthetic process relationship: RO:0002211 GO:0016051 ! regulates carbohydrate biosynthetic process [Term] id: GO:0043264 name: extracellular membraneless organelle def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:jl] synonym: "extracellular non-membrane-bounded organelle" EXACT [] synonym: "extracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! membraneless organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043228 ! membraneless organelle intersection_of: part_of GO:0005576 ! extracellular region property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29106" xsd:anyURI [Term] id: GO:0043269 name: regulation of monoatomic ion transport def: "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "regulation of ion transport" BROAD [] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006811 ! regulates monoatomic ion transport relationship: RO:0002211 GO:0006811 ! regulates monoatomic ion transport [Term] id: GO:0043270 name: positive regulation of monoatomic ion transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "activation of ion transport" NARROW [] synonym: "stimulation of ion transport" NARROW [] synonym: "up regulation of ion transport" EXACT [] synonym: "up-regulation of ion transport" EXACT [] synonym: "upregulation of ion transport" EXACT [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006811 ! positively regulates monoatomic ion transport relationship: RO:0002213 GO:0006811 ! positively regulates monoatomic ion transport [Term] id: GO:0043271 name: negative regulation of monoatomic ion transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "down regulation of ion transport" EXACT [] synonym: "down-regulation of ion transport" EXACT [] synonym: "downregulation of ion transport" EXACT [] synonym: "inhibition of ion transport" NARROW [] synonym: "negative regulation of ion transport" BROAD [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006811 ! negatively regulates monoatomic ion transport relationship: RO:0002212 GO:0006811 ! negatively regulates monoatomic ion transport [Term] id: GO:0043279 name: response to alkaloid def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:jl] is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:22315 ! has primary input alkaloid relationship: RO:0004009 CHEBI:22315 ! has primary input alkaloid [Term] id: GO:0043282 name: chordate pharyngeal muscle development def: "The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx." [GOC:go_curators] is_a: GO:0007517 ! muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000933 ! results in development of chordate pharyngeal muscle relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0160093 ! chordate pharynx development relationship: RO:0002296 UBERON:0000933 ! results in development of chordate pharyngeal muscle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18285" xsd:anyURI [Term] id: GO:0043292 name: contractile muscle fiber def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194] synonym: "contractile fibre" EXACT [] is_a: GO:0043232 ! intracellular membraneless organelle is_a: GO:0099512 ! supramolecular fiber relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000187 ! muscle cell relationship: part_of GO:0005737 ! cytoplasm property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27281" xsd:anyURI [Term] id: GO:0043362 name: nucleate erythrocyte maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." [GOC:devbiol, GOC:jl] synonym: "nucleate RBC maturation" EXACT [CL:0000232] synonym: "nucleate red blood cell maturation" EXACT [CL:0000232] is_a: GO:0043249 ! erythrocyte maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000562 ! results in maturation of nucleate erythrocyte relationship: part_of GO:0048823 ! nucleate erythrocyte development relationship: RO:0002299 CL:0000562 ! results in maturation of nucleate erythrocyte [Term] id: GO:0043363 name: nucleate erythrocyte differentiation def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." [GOC:jl] synonym: "nucleate RBC differentiation" EXACT [CL:0000232] synonym: "nucleate red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0030218 ! erythrocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000562 ! results in acquisition of features of nucleate erythrocyte relationship: RO:0002315 CL:0000562 ! results in acquisition of features of nucleate erythrocyte [Term] id: GO:0043434 name: response to peptide hormone def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [PMID:11027914, PMID:15134857, Wikipedia:Peptide_hormone] synonym: "response to peptide hormone stimulus" EXACT [GOC:dos] synonym: "response to polypeptide hormone stimulus" EXACT [] is_a: GO:0009725 ! response to hormone is_a: GO:1901698 ! response to nitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:25905 ! has primary input peptide hormone relationship: RO:0004009 CHEBI:25905 ! has primary input peptide hormone property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0043436 name: oxoacid metabolic process def: "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [Wikipedia:Oxyacid] synonym: "keto acid metabolic process" EXACT [] synonym: "keto acid metabolism" EXACT [] synonym: "ketoacid metabolic process" EXACT [] synonym: "ketoacid metabolism" EXACT [] synonym: "oxo acid metabolic process" EXACT [] synonym: "oxo acid metabolism" EXACT [] synonym: "oxoacid metabolism" EXACT [] is_a: GO:0006082 ! organic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35406 ! has primary input or output oxoanion relationship: RO:0004007 CHEBI:35406 ! has primary input or output oxoanion [Term] id: GO:0043455 name: regulation of secondary metabolic process def: "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] synonym: "regulation of secondary metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019748 ! regulates secondary metabolic process relationship: RO:0002211 GO:0019748 ! regulates secondary metabolic process [Term] id: GO:0043467 name: regulation of generation of precursor metabolites and energy def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." [GOC:jl] xref: Reactome:R-HSA-163685 "Integration of energy metabolism" is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006091 ! regulates generation of precursor metabolites and energy relationship: RO:0002211 GO:0006091 ! regulates generation of precursor metabolites and energy [Term] id: GO:0043470 name: regulation of carbohydrate catabolic process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." [GOC:mlg] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016052 ! regulates carbohydrate catabolic process relationship: RO:0002211 GO:0016052 ! regulates carbohydrate catabolic process [Term] id: GO:0043473 name: pigmentation def: "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." [GOC:jl] subset: goslim_chembl subset: goslim_pir is_a: GO:0008150 ! biological process relationship: in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0043500 name: muscle adaptation def: "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] subset: goslim_pir synonym: "muscle plasticity" RELATED [] is_a: GO:0003012 ! muscle system process is_a: GO:0050896 ! response to stimulus relationship: BFO:0000066 UBERON:0002385 ! occurs in muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0043501 name: skeletal muscle adaptation def: "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] synonym: "skeletal muscle plasticity" RELATED [] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue relationship: BFO:0000066 UBERON:0001134 ! occurs in skeletal muscle tissue property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0043502 name: regulation of muscle adaptation def: "Any process that modulates the frequency, rate or extent of muscle adaptation." [GOC:go_curators, GOC:mtg_muscle] synonym: "regulation of muscle plasticity" RELATED [] is_a: GO:0048583 ! regulation of response to stimulus is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043500 ! regulates muscle adaptation relationship: RO:0002211 GO:0043500 ! regulates muscle adaptation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0043523 name: regulation of neuron apoptotic process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of neuronal cells" EXACT [] synonym: "regulation of apoptosis of neurons" EXACT [] synonym: "regulation of neuron apoptosis" NARROW [] synonym: "regulation of neuron programmed cell death" EXACT [] synonym: "regulation of neuronal cell programmed cell death" EXACT [] synonym: "regulation of programmed cell death of neuronal cells" EXACT [] synonym: "regulation of programmed cell death, neurons" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051402 ! regulates neuron apoptotic process relationship: RO:0002211 GO:0051402 ! regulates neuron apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0043524 name: negative regulation of neuron apoptotic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "down regulation of neuron apoptosis" EXACT [] synonym: "down-regulation of neuron apoptosis" EXACT [] synonym: "downregulation of neuron apoptosis" EXACT [] synonym: "inhibition of neuron apoptosis" NARROW [] synonym: "negative regulation of neuron apoptosis" NARROW [] synonym: "negative regulation of programmed cell death, neurons" EXACT [] synonym: "neuron survival" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051402 ! negatively regulates neuron apoptotic process relationship: RO:0002212 GO:0051402 ! negatively regulates neuron apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0043525 name: positive regulation of neuron apoptotic process def: "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "activation of neuron apoptosis" NARROW [] synonym: "positive regulation of neuron apoptosis" NARROW [] synonym: "positive regulation of programmed cell death, neurons" EXACT [] synonym: "stimulation of neuron apoptosis" NARROW [] synonym: "up regulation of neuron apoptosis" EXACT [] synonym: "up-regulation of neuron apoptosis" EXACT [] synonym: "upregulation of neuron apoptosis" EXACT [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051402 ! positively regulates neuron apoptotic process relationship: RO:0002213 GO:0051402 ! positively regulates neuron apoptotic process property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0043534 name: blood vessel endothelial cell migration def: "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." [PMID:11166264] is_a: GO:0043542 ! endothelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000071 ! results in movement of blood vessel endothelial cell relationship: RO:0002565 CL:0000071 ! results in movement of blood vessel endothelial cell property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0043535 name: regulation of blood vessel endothelial cell migration def: "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] is_a: GO:0010594 ! regulation of endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043534 ! regulates blood vessel endothelial cell migration relationship: RO:0002211 GO:0043534 ! regulates blood vessel endothelial cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0043536 name: positive regulation of blood vessel endothelial cell migration def: "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "activation of blood vessel endothelial cell migration" NARROW [] synonym: "stimulation of blood vessel endothelial cell migration" NARROW [] synonym: "up regulation of blood vessel endothelial cell migration" EXACT [] synonym: "up-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "upregulation of blood vessel endothelial cell migration" EXACT [] is_a: GO:0010595 ! positive regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043534 ! positively regulates blood vessel endothelial cell migration relationship: RO:0002213 GO:0043534 ! positively regulates blood vessel endothelial cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0043537 name: negative regulation of blood vessel endothelial cell migration def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "down regulation of blood vessel endothelial cell migration" EXACT [] synonym: "down-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "downregulation of blood vessel endothelial cell migration" EXACT [] synonym: "inhibition of blood vessel endothelial cell migration" NARROW [] is_a: GO:0010596 ! negative regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043534 ! negatively regulates blood vessel endothelial cell migration relationship: RO:0002212 GO:0043534 ! negatively regulates blood vessel endothelial cell migration property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0043542 name: endothelial cell migration def: "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:go_curators] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000115 ! results in movement of endothelial cell relationship: RO:0002565 CL:0000115 ! results in movement of endothelial cell property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0043576 name: regulation of respiratory gaseous exchange def: "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007585 ! regulates respiratory gaseous exchange by respiratory system relationship: RO:0002211 GO:0007585 ! regulates respiratory gaseous exchange by respiratory system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0043583 name: ear development def: "The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GOC:jl, ISBN:0192801023] synonym: "hearing organ development" EXACT [] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001690 ! results in development of ear relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002296 UBERON:0001690 ! results in development of ear [Term] id: GO:0043584 name: nose development def: "The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [GOC:jl] synonym: "nasus development" EXACT [] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000004 ! results in development of nose relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060541 ! respiratory system development relationship: RO:0002296 UBERON:0000004 ! results in development of nose [Term] id: GO:0043585 name: nose morphogenesis def: "The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [GOC:jl] synonym: "nasus morphogenesis" EXACT [] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000004 ! results in morphogenesis of nose relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0043584 ! nose development relationship: RO:0002298 UBERON:0000004 ! results in morphogenesis of nose [Term] id: GO:0043586 name: tongue development def: "The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." [GOC:jl, UBERON:0001723] synonym: "glossa development" NARROW [] synonym: "lingua development" NARROW [] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001723 ! results in development of tongue relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002296 UBERON:0001723 ! results in development of tongue [Term] id: GO:0043587 name: tongue morphogenesis def: "The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." [GOC:jl, UBERON:0001723] synonym: "glossa morphogenesis" NARROW [] synonym: "lingua morphogenesis" EXACT [] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001723 ! results in morphogenesis of tongue relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043586 ! tongue development relationship: RO:0002298 UBERON:0001723 ! results in morphogenesis of tongue [Term] id: GO:0043588 name: skin development namespace: biological_process def: "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] synonym: "animal skin development" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002097 ! results in development of skin of body relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002296 UBERON:0002097 ! results in development of skin of body [Term] id: GO:0043589 name: skin morphogenesis def: "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002097 ! results in morphogenesis of skin of body relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043588 ! skin development relationship: RO:0002298 UBERON:0002097 ! results in morphogenesis of skin of body [Term] id: GO:0043603 name: amide metabolic process def: "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "amide metabolism" EXACT [] synonym: "cellular amide metabolic process" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:32988 ! has primary input or output amide relationship: RO:0004007 CHEBI:32988 ! has primary input or output amide property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI [Term] id: GO:0043604 name: amide biosynthetic process def: "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] is_a: GO:0009058 ! biosynthetic process is_a: GO:0043603 ! amide metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:32988 ! has primary output amide relationship: RO:0004008 CHEBI:32988 ! has primary output amide [Term] id: GO:0043605 name: amide catabolic process def: "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] synonym: "cellular amide catabolic process" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0043603 ! amide metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004008 CHEBI:32988 ! has primary output amide relationship: RO:0004008 CHEBI:32988 ! has primary output amide [Term] id: GO:0043648 name: dicarboxylic acid metabolic process def: "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "dicarboxylate metabolic process" EXACT [] synonym: "dicarboxylate metabolism" EXACT [] synonym: "dicarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:35693 ! has primary input or output dicarboxylic acid anion relationship: RO:0004007 CHEBI:35693 ! has primary input or output dicarboxylic acid anion [Term] id: GO:0043649 name: dicarboxylic acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate catabolic process" EXACT [] synonym: "dicarboxylate catabolism" EXACT [] synonym: "dicarboxylic acid breakdown" EXACT [] synonym: "dicarboxylic acid catabolism" EXACT [] synonym: "dicarboxylic acid degradation" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion relationship: RO:0004009 CHEBI:35693 ! has primary input dicarboxylic acid anion [Term] id: GO:0043650 name: dicarboxylic acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate biosynthesis" EXACT [] synonym: "dicarboxylate biosynthetic process" EXACT [] synonym: "dicarboxylic acid anabolism" EXACT [] synonym: "dicarboxylic acid biosynthesis" EXACT [] synonym: "dicarboxylic acid formation" EXACT [] synonym: "dicarboxylic acid synthesis" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35693 ! has primary output dicarboxylic acid anion relationship: RO:0004008 CHEBI:35693 ! has primary output dicarboxylic acid anion [Term] id: GO:0043931 name: ossification involved in bone maturation def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." [GOC:dph, GOC:mah, GOC:mtg_mpo] synonym: "ossification involved in bone modeling" NARROW [GO_REF:0000034] synonym: "ossification involved in skeletal development" EXACT [GOC:dph] is_a: GO:0001503 ! ossification intersection_of: GO:0001503 ! ossification intersection_of: part_of GO:0070977 ! bone maturation relationship: part_of GO:0070977 ! bone maturation [Term] id: GO:0043933 name: protein-containing complex organization alt_id: GO:0034600 alt_id: GO:0034621 alt_id: GO:0071822 def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." [GOC:mah] synonym: "cellular macromolecular complex organization" RELATED [] synonym: "cellular macromolecular complex subunit organisation" RELATED [] synonym: "cellular macromolecular complex subunit organization" RELATED [] synonym: "macromolecular complex organization" RELATED [] synonym: "macromolecular complex subunit organisation" RELATED [] synonym: "macromolecular complex subunit organization" RELATED [] synonym: "protein complex subunit organisation" EXACT [GOC:mah] synonym: "protein complex subunit organization" EXACT [] synonym: "protein-containing complex subunit organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0032991 ! results in organization of protein-containing complex relationship: RO:0002592 GO:0032991 ! results in organization of protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI created_by: mah creation_date: 2010-09-08T10:01:42Z [Term] id: GO:0044042 name: glucan metabolic process def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." [GOC:jl] synonym: "glucan metabolism" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:37163 ! has primary input or output glucan relationship: RO:0004007 CHEBI:37163 ! has primary input or output glucan [Term] id: GO:0044057 name: regulation of system process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003008 ! regulates system process relationship: RO:0002211 GO:0003008 ! regulates system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0044058 name: regulation of digestive system process def: "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jl] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022600 ! regulates digestive system process relationship: RO:0002211 GO:0022600 ! regulates digestive system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0044060 name: regulation of endocrine process def: "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [GOC:jl] synonym: "regulation of endocrine system process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050886 ! regulates endocrine process relationship: RO:0002211 GO:0050886 ! regulates endocrine process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0044062 name: regulation of excretion def: "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." [GOC:jl] is_a: GO:0044057 ! regulation of system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007588 ! regulates excretion relationship: RO:0002211 GO:0007588 ! regulates excretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0044065 name: regulation of respiratory system process def: "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." [GOC:jl] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003016 ! regulates respiratory system process relationship: RO:0002211 GO:0003016 ! regulates respiratory system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0044085 name: cellular component biogenesis alt_id: GO:0071843 def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." [GOC:jl, GOC:mah] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "cellular component biogenesis at cellular level" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27194" xsd:anyURI [Term] id: GO:0044087 name: regulation of cellular component biogenesis def: "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] subset: gocheck_do_not_annotate is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044085 ! regulates cellular component biogenesis relationship: RO:0002211 GO:0044085 ! regulates cellular component biogenesis [Term] id: GO:0044088 name: regulation of vacuole organization def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "regulation of vacuole biogenesis" RELATED [GOC:mah] synonym: "regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007033 ! regulates vacuole organization relationship: RO:0002211 GO:0007033 ! regulates vacuole organization [Term] id: GO:0044089 name: positive regulation of cellular component biogenesis def: "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044085 ! positively regulates cellular component biogenesis relationship: RO:0002213 GO:0044085 ! positively regulates cellular component biogenesis [Term] id: GO:0044090 name: positive regulation of vacuole organization def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "positive regulation of vacuole biogenesis" RELATED [GOC:mah] synonym: "positive regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044088 ! regulation of vacuole organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007033 ! positively regulates vacuole organization relationship: RO:0002213 GO:0007033 ! positively regulates vacuole organization [Term] id: GO:0044091 name: membrane biogenesis def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." [GOC:jl] is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: RO:0004008 GO:0016020 ! has primary output membrane relationship: RO:0004008 GO:0016020 ! has primary output membrane [Term] id: GO:0044092 name: negative regulation of molecular function def: "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] subset: gocheck_do_not_annotate is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003674 ! negatively regulates molecular_function relationship: RO:0002212 GO:0003674 ! negatively regulates molecular_function created_by: jl creation_date: 2009-04-21T04:07:27Z [Term] id: GO:0044093 name: positive regulation of molecular function def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] subset: gocheck_obsoletion_candidate is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003674 ! positively regulates molecular_function relationship: RO:0002213 GO:0003674 ! positively regulates molecular_function created_by: jl creation_date: 2009-04-21T04:11:06Z [Term] id: GO:0044207 name: translation initiation ternary complex def: "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:jl] synonym: "Met-tRNA/eIF2.GTP ternary complex" NARROW [] synonym: "translation initiation (ternary) complex" EXACT [] is_a: GO:1990904 ! ribonucleoprotein complex relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005737 ! cytoplasm created_by: jl creation_date: 2009-10-22T02:38:55Z [Term] id: GO:0044238 name: primary metabolic process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_euk_cellular_processes_ribbon subset: goslim_pir subset: goslim_plant_ribbon subset: goslim_prokaryote_ribbon synonym: "primary metabolism" EXACT [] xref: Wikipedia:Primary_metabolite is_a: GO:0008152 ! metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044258 name: intestinal lipid catabolic process def: "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas." [GOC:jl, PMID:7018485] synonym: "intestinal lipid breakdown" EXACT [] synonym: "intestinal lipid catabolism" EXACT [] synonym: "intestinal lipid degradation" EXACT [] is_a: GO:0016042 ! lipid catabolic process intersection_of: GO:0016042 ! lipid catabolic process intersection_of: BFO:0000066 UBERON:0000160 ! occurs in intestine relationship: BFO:0000066 UBERON:0000160 ! occurs in intestine [Term] id: GO:0044272 name: sulfur compound biosynthetic process def: "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur biosynthesis" NARROW [] synonym: "sulfur biosynthetic process" NARROW [] synonym: "sulfur compound anabolism" EXACT [] synonym: "sulfur compound biosynthesis" EXACT [] synonym: "sulfur compound formation" EXACT [] synonym: "sulfur compound synthesis" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:26835 ! has primary output sulfur molecular entity relationship: RO:0004008 CHEBI:26835 ! has primary output sulfur molecular entity [Term] id: GO:0044273 name: sulfur compound catabolic process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur catabolic process" NARROW [] synonym: "sulfur catabolism" NARROW [] synonym: "sulfur compound breakdown" EXACT [] synonym: "sulfur compound catabolism" EXACT [] synonym: "sulfur compound degradation" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity relationship: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity [Term] id: GO:0044281 name: small molecule metabolic process def: "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics synonym: "small molecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process created_by: jl creation_date: 2010-01-26T12:05:20Z [Term] id: GO:0044282 name: small molecule catabolic process def: "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. synonym: "small molecule catabolism" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0044281 ! small molecule metabolic process created_by: jl creation_date: 2010-01-26T12:06:10Z [Term] id: GO:0044283 name: small molecule biosynthetic process def: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. subset: goslim_prokaryote subset: goslim_prokaryote_ribbon synonym: "small molecule biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044281 ! small molecule metabolic process created_by: jl creation_date: 2010-01-26T12:06:49Z [Term] id: GO:0044297 name: cell body def: "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." [GOC:go_curators] comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. synonym: "cell soma" EXACT [] xref: FBbt:00005107 xref: FMA:67301 xref: Wikipedia:Cell_body is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of CL:0000000 ! cell property_value: RO:0002161 NCBITaxon:4890 created_by: jl creation_date: 2010-02-05T10:37:16Z [Term] id: GO:0044342 name: type B pancreatic cell proliferation def: "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin." [GOC:jl, GOC:yaf] synonym: "pancreatic B cell proliferation" EXACT [GOC:mah] synonym: "pancreatic beta cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000169 ! acts on population of type B pancreatic cell relationship: RO:0012003 CL:0000169 ! acts on population of type B pancreatic cell property_value: RO:0002161 NCBITaxon:4751 created_by: jl creation_date: 2010-08-25T01:44:51Z [Term] id: GO:0044346 name: fibroblast apoptotic process def: "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057, GOC:jl, GOC:mtg_apoptosis, GOC:yaf] synonym: "fibroblast apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000057 ! occurs in fibroblast relationship: BFO:0000066 CL:0000057 ! occurs in fibroblast property_value: RO:0002161 NCBITaxon:4896 created_by: jl creation_date: 2010-09-23T11:33:38Z [Term] id: GO:0044380 name: protein localization to cytoskeleton def: "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." [GOC:jl] synonym: "protein localisation to cytoskeleton" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005856 ! has target end location cytoskeleton relationship: RO:0002339 GO:0005856 ! has target end location cytoskeleton created_by: jl creation_date: 2011-12-13T11:43:24Z [Term] id: GO:0044419 name: biological process involved in interspecies interaction between organisms def: "Any process evolved to enable an interaction with an organism of a different species." [GOC:cc] subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_pir synonym: "interaction with another species" EXACT [] synonym: "interspecies interaction" EXACT [] synonym: "interspecies interaction between organisms" EXACT [] synonym: "interspecies interaction with other organisms" EXACT [] xref: Reactome:R-HSA-9824443 "Parasitic Infection Pathways" is_a: GO:0008150 ! biological process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20191" xsd:anyURI property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0044423 name: virion component def: "Any constituent part of a virion, a complete fully infectious extracellular virus particle." [] is_a: GO:0005575 ! cellular_component [Term] id: GO:0044458 name: motile cilium assembly alt_id: GO:1903887 def: "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:19776033, PMID:21129373, ZFIN:dsf] synonym: "motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "motile primary cilium assembly" RELATED [] synonym: "motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:0060271 ! cilium assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0031514 ! results in assembly of motile cilium relationship: RO:0002588 GO:0031514 ! results in assembly of motile cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2015-02-06T17:23:23Z [Term] id: GO:0044550 name: secondary metabolite biosynthetic process def: "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] subset: goslim_prokaryote synonym: "secondary metabolite biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0019748 ! secondary metabolic process created_by: jl creation_date: 2012-03-29T01:55:18Z [Term] id: GO:0044565 name: dendritic cell proliferation def: "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, PMID:18469816] is_a: GO:0032943 ! mononuclear cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000451 ! acts on population of dendritic cell relationship: RO:0012003 CL:0000451 ! acts on population of dendritic cell created_by: jl creation_date: 2012-04-05T04:31:39Z [Term] id: GO:0044566 name: chondrocyte activation def: "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." [CL:0000138, GOC:jl] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000138 ! has primary input chondrocyte relationship: RO:0004009 CL:0000138 ! has primary input chondrocyte created_by: jl creation_date: 2012-04-05T04:45:38Z [Term] id: GO:0044703 name: multi-organism reproductive process namespace: biological_process def: "A biological process that directly contributes to the process of producing new individuals, involving another organism." [GOC:jl] subset: gocheck_do_not_annotate subset: goslim_drosophila is_a: GO:0022414 ! reproductive process created_by: jl creation_date: 2012-09-19T15:56:30Z [Term] id: GO:0044706 name: multi-multicellular organism process namespace: biological_process def: "A multicellular organism process which involves another multicellular organism of the same or different species." [GOC:jl] is_a: GO:0032501 ! multicellular organismal process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21459" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2012-09-19T16:06:16Z [Term] id: GO:0044743 name: protein transmembrane import into intracellular organelle def: "The directed movement of proteins into an intracellular organelle, across a membrane." [GOC:jl] is_a: GO:0033365 ! protein localization to organelle is_a: GO:0065002 ! intracellular protein transmembrane transport is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0043229 ! has target end location intracellular organelle intersection_of: RO:0002342 GO:0031090 ! results in transport across organelle membrane intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0002338 GO:0005829 ! has target start location cytosol relationship: RO:0002339 GO:0043229 ! has target end location intracellular organelle relationship: RO:0002342 GO:0031090 ! results in transport across organelle membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29962" xsd:anyURI created_by: jl creation_date: 2012-11-07T15:37:36Z [Term] id: GO:0044782 name: cilium organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:jl] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. subset: goslim_drosophila subset: goslim_generic synonym: "microtubule-based flagellum organization" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005929 ! results in organization of cilium relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002592 GO:0005929 ! results in organization of cilium created_by: jl creation_date: 2013-03-27T15:09:58Z [Term] id: GO:0044848 name: biological phase namespace: biological_process def: "A distinct period or stage in a biological process or cycle." [GOC:jl] comment: Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase. subset: gocheck_do_not_annotate is_a: GO:0008150 ! biological process disjoint_from: GO:0050896 ! response to stimulus disjoint_from: GO:0051179 ! localization created_by: jl creation_date: 2014-07-16T13:12:40Z [Term] id: GO:0044851 name: hair cycle phase namespace: biological_process def: "The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body." [GOC:jl] comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). subset: gocheck_do_not_annotate is_a: GO:0044848 ! biological phase created_by: jl creation_date: 2014-07-16T14:22:09Z [Term] id: GO:0045026 name: plasma membrane fusion alt_id: GO:0006947 def: "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." [GOC:elh, GOC:mtg_muscle] synonym: "cell fusion" BROAD [] synonym: "cell-cell fusion" BROAD [] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0061025 ! membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005886 ! results in fusion of plasma membrane relationship: RO:0012008 GO:0005886 ! results in fusion of plasma membrane [Term] id: GO:0045095 name: keratin filament def: "A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins." [ISBN:0716731363] synonym: "acidic keratin" RELATED [] synonym: "basic/neutral keratin" RELATED [] is_a: GO:0005882 ! intermediate filament [Term] id: GO:0045103 name: intermediate filament-based process def: "Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins." [GOC:ai] is_a: GO:0009987 ! cellular process [Term] id: GO:0045104 name: intermediate filament cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins." [GOC:ai] synonym: "intermediate filament cytoskeleton organisation" EXACT [] synonym: "intermediate filament cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0045103 ! intermediate filament-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0045111 ! results in organization of intermediate filament cytoskeleton relationship: RO:0002592 GO:0045111 ! results in organization of intermediate filament cytoskeleton [Term] id: GO:0045109 name: intermediate filament organization def: "Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:ai] synonym: "intermediate filament organisation" EXACT [] is_a: GO:0045104 ! intermediate filament cytoskeleton organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005882 ! results in organization of intermediate filament relationship: RO:0002592 GO:0005882 ! results in organization of intermediate filament [Term] id: GO:0045110 name: intermediate filament bundle assembly def: "The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs." [ISBN:0716731363] synonym: "tonofilament assembly" NARROW [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0045109 ! intermediate filament organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002592 GO:0005882 ! results in organization of intermediate filament [Term] id: GO:0045111 name: intermediate filament cytoskeleton def: "Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell." [ISBN:0716731363] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0045120 name: pronucleus def: "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." [ISBN:0198506732] xref: Wikipedia:Pronucleus is_a: GO:0005634 ! nucleus relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0045132 name: meiotic chromosome segregation def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GOC:ai, GOC:mah] is_a: GO:0098813 ! nuclear chromosome segregation is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0140013 ! meiotic nuclear division relationship: part_of GO:0140013 ! meiotic nuclear division [Term] id: GO:0045137 name: development of primary sexual characteristics def: "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0007275 ! multicellular organism development relationship: part_of GO:0007548 ! sex differentiation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045144 name: meiotic sister chromatid segregation def: "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194] synonym: "meiosis II, chromosome segregation" EXACT [] is_a: GO:0000819 ! sister chromatid segregation is_a: GO:0045132 ! meiotic chromosome segregation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0000819 ! sister chromatid segregation intersection_of: part_of GO:0007135 ! meiosis II relationship: part_of GO:0007135 ! meiosis II [Term] id: GO:0045165 name: cell fate commitment def: "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." [ISBN:0716731185] comment: Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created. is_a: GO:0048869 ! cellular developmental process relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0030154 ! cell differentiation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0045168 name: cell-cell signaling involved in cell fate commitment def: "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "cell fate commitment, cell-cell signaling" EXACT [] synonym: "cell fate commitment, cell-cell signalling" EXACT [] synonym: "cell-cell signaling during in cell fate commitment" EXACT [] synonym: "cell-cell signaling resulting in cell fate commitment" EXACT [] synonym: "cell-cell signalling during cell fate commitment" EXACT [] synonym: "cell-cell signalling involved in cell fate specification" NARROW [GOC:dph, GOC:tb] synonym: "cell-cell signalling resulting in cell fate commitment" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0045165 ! cell fate commitment relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0045165 ! cell fate commitment [Term] id: GO:0045184 name: establishment of protein localization def: "The directed movement of a protein to a specific location." [GOC:bf] synonym: "establishment of protein localisation" EXACT [GOC:mah] synonym: "protein positioning" EXACT [] synonym: "protein recruitment" EXACT [] is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: RO:0004009 CHEBI:36080 ! has primary input protein [Term] id: GO:0045185 name: maintenance of protein location def: "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away." [GOC:bf] synonym: "active protein retrieval" NARROW [] synonym: "maintenance of protein localization" RELATED [GOC:dph, GOC:tb] synonym: "protein retention" NARROW [] synonym: "protein sequestering" NARROW [] is_a: GO:0051235 ! maintenance of location relationship: part_of GO:0008104 ! intracellular protein localization [Term] id: GO:0045196 name: establishment or maintenance of neuroblast polarity alt_id: GO:0043339 alt_id: GO:0043342 def: "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mah, GOC:mtg_sensu, PMID:19375318, PMID:20066083] synonym: "establishment and/or maintenance of neuroblast cell polarity" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0055059 ! asymmetric neuroblast division [Term] id: GO:0045200 name: establishment of neuroblast polarity alt_id: GO:0043340 alt_id: GO:0043343 def: "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mtg_sensu] synonym: "establishment of neuroblast cell polarity" EXACT [] is_a: GO:0030010 ! establishment of cell polarity is_a: GO:0045196 ! establishment or maintenance of neuroblast polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000031 ! occurs in neuroblast (sensu Vertebrata) relationship: BFO:0000066 CL:0000031 ! occurs in neuroblast (sensu Vertebrata) [Term] id: GO:0045202 name: synapse def: "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110] subset: goslim_agr subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_synapse synonym: "electrotonic synapse" RELATED [NIF_Subcellular:sao1311109124] synonym: "mixed synapse" NARROW [NIF_Subcellular:sao1506103497] synonym: "synaptic junction" EXACT [] xref: NIF_Subcellular:sao914572699 xref: Wikipedia:Chemical_synapse is_a: GO:0030054 ! cell junction relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0045214 name: sarcomere organization alt_id: GO:0006938 def: "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:bf] synonym: "sarcomere alignment" EXACT [] synonym: "sarcomere organisation" EXACT [] is_a: GO:0031032 ! actomyosin structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030017 ! results in organization of sarcomere relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0030239 ! myofibril assembly relationship: RO:0002592 GO:0030017 ! results in organization of sarcomere [Term] id: GO:0045216 name: cell-cell junction organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] synonym: "cell-cell junction assembly and maintenance" EXACT [] synonym: "cell-cell junction biogenesis" RELATED [] synonym: "cell-cell junction organisation" EXACT [GOC:mah] synonym: "intercellular junction assembly and maintenance" EXACT [] xref: Reactome:R-HSA-421270 "Cell-cell junction organization" is_a: GO:0034330 ! cell junction organization intersection_of: GO:0034330 ! cell junction organization intersection_of: RO:0002592 GO:0005911 ! results in organization of cell-cell junction relationship: RO:0002592 GO:0005911 ! results in organization of cell-cell junction [Term] id: GO:0045229 name: external encapsulating structure organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "external encapsulating structure organisation" EXACT [] synonym: "external encapsulating structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0030312 ! results in organization of external encapsulating structure relationship: RO:0002592 GO:0030312 ! results in organization of external encapsulating structure [Term] id: GO:0045321 name: leukocyte activation def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add] synonym: "immune cell activation" EXACT [] synonym: "leucocyte activation" EXACT [] xref: Wikipedia:Immunologic_activation is_a: GO:0001775 ! cell activation is_a: GO:0002376 ! immune system process intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000738 ! has primary input leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0004009 CL:0000738 ! has primary input leukocyte [Term] id: GO:0045444 name: fat cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." [CL:0000136, GOC:go_curators] synonym: "adipocyte cell differentiation" EXACT [] synonym: "adipocyte differentiation" EXACT [] synonym: "adipogenesis" RELATED [] synonym: "adipose cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000136 ! results in acquisition of features of adipocyte relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002315 CL:0000136 ! results in acquisition of features of adipocyte [Term] id: GO:0045445 name: myoblast differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "myoblast cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000056 ! results in acquisition of features of myoblast relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0061061 ! muscle structure development relationship: RO:0002315 CL:0000056 ! results in acquisition of features of myoblast [Term] id: GO:0045446 name: endothelial cell differentiation def: "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [CL:0000115, GOC:go_curators] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000115 ! results in acquisition of features of endothelial cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003158 ! endothelium development relationship: RO:0002315 CL:0000115 ! results in acquisition of features of endothelial cell [Term] id: GO:0045580 name: regulation of T cell differentiation def: "Any process that modulates the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "regulation of T cell development" RELATED [GOC:add] synonym: "regulation of T lymphocyte differentiation" EXACT [] synonym: "regulation of T-cell differentiation" EXACT [] synonym: "regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030217 ! regulates T cell differentiation relationship: RO:0002211 GO:0030217 ! regulates T cell differentiation [Term] id: GO:0045581 name: negative regulation of T cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "down regulation of T cell differentiation" EXACT [] synonym: "down-regulation of T cell differentiation" EXACT [] synonym: "downregulation of T cell differentiation" EXACT [] synonym: "inhibition of T cell differentiation" NARROW [] synonym: "negative regulation of T cell development" RELATED [GOC:add] synonym: "negative regulation of T lymphocyte differentiation" EXACT [] synonym: "negative regulation of T-cell differentiation" EXACT [] synonym: "negative regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045620 ! negative regulation of lymphocyte differentiation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030217 ! negatively regulates T cell differentiation relationship: RO:0002212 GO:0030217 ! negatively regulates T cell differentiation [Term] id: GO:0045582 name: positive regulation of T cell differentiation def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "activation of T cell differentiation" NARROW [] synonym: "positive regulation of T cell development" RELATED [GOC:add] synonym: "positive regulation of T lymphocyte differentiation" EXACT [] synonym: "positive regulation of T-cell differentiation" EXACT [] synonym: "positive regulation of T-lymphocyte differentiation" EXACT [] synonym: "stimulation of T cell differentiation" NARROW [] synonym: "up regulation of T cell differentiation" EXACT [] synonym: "up-regulation of T cell differentiation" EXACT [] synonym: "upregulation of T cell differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045621 ! positive regulation of lymphocyte differentiation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030217 ! positively regulates T cell differentiation relationship: RO:0002213 GO:0030217 ! positively regulates T cell differentiation [Term] id: GO:0045595 name: regulation of cell differentiation def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030154 ! regulates cell differentiation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0030154 ! regulates cell differentiation [Term] id: GO:0045596 name: negative regulation of cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "down regulation of cell differentiation" EXACT [] synonym: "down-regulation of cell differentiation" EXACT [] synonym: "downregulation of cell differentiation" EXACT [] synonym: "inhibition of cell differentiation" NARROW [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030154 ! negatively regulates cell differentiation relationship: RO:0002212 GO:0030154 ! negatively regulates cell differentiation [Term] id: GO:0045597 name: positive regulation of cell differentiation def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "activation of cell differentiation" NARROW [] synonym: "stimulation of cell differentiation" NARROW [] synonym: "up regulation of cell differentiation" EXACT [] synonym: "up-regulation of cell differentiation" EXACT [] synonym: "upregulation of cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030154 ! positively regulates cell differentiation relationship: RO:0002213 GO:0030154 ! positively regulates cell differentiation [Term] id: GO:0045598 name: regulation of fat cell differentiation def: "Any process that modulates the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "regulation of adipocyte cell differentiation" EXACT [] synonym: "regulation of adipocyte differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045444 ! regulates fat cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0045444 ! regulates fat cell differentiation [Term] id: GO:0045599 name: negative regulation of fat cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "down regulation of fat cell differentiation" EXACT [] synonym: "down-regulation of fat cell differentiation" EXACT [] synonym: "downregulation of fat cell differentiation" EXACT [] synonym: "inhibition of fat cell differentiation" NARROW [] synonym: "negative regulation of adipocyte cell differentiation" EXACT [] synonym: "negative regulation of adipocyte differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045444 ! negatively regulates fat cell differentiation relationship: RO:0002212 GO:0045444 ! negatively regulates fat cell differentiation [Term] id: GO:0045600 name: positive regulation of fat cell differentiation def: "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "activation of fat cell differentiation" NARROW [] synonym: "positive regulation of adipocyte cell differentiation" EXACT [] synonym: "positive regulation of adipocyte differentiation" EXACT [] synonym: "stimulation of fat cell differentiation" NARROW [] synonym: "up regulation of fat cell differentiation" EXACT [] synonym: "up-regulation of fat cell differentiation" EXACT [] synonym: "upregulation of fat cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045444 ! positively regulates fat cell differentiation relationship: RO:0002213 GO:0045444 ! positively regulates fat cell differentiation [Term] id: GO:0045601 name: regulation of endothelial cell differentiation def: "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045446 ! regulates endothelial cell differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0045446 ! regulates endothelial cell differentiation [Term] id: GO:0045602 name: negative regulation of endothelial cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "down regulation of endothelial cell differentiation" EXACT [] synonym: "down-regulation of endothelial cell differentiation" EXACT [] synonym: "downregulation of endothelial cell differentiation" EXACT [] synonym: "inhibition of endothelial cell differentiation" NARROW [] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045446 ! negatively regulates endothelial cell differentiation relationship: RO:0002212 GO:0045446 ! negatively regulates endothelial cell differentiation [Term] id: GO:0045603 name: positive regulation of endothelial cell differentiation def: "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "activation of endothelial cell differentiation" NARROW [] synonym: "stimulation of endothelial cell differentiation" NARROW [] synonym: "up regulation of endothelial cell differentiation" EXACT [] synonym: "up-regulation of endothelial cell differentiation" EXACT [] synonym: "upregulation of endothelial cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045446 ! positively regulates endothelial cell differentiation relationship: RO:0002213 GO:0045446 ! positively regulates endothelial cell differentiation [Term] id: GO:0045604 name: regulation of epidermal cell differentiation def: "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045682 ! regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009913 ! regulates epidermal cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0009913 ! regulates epidermal cell differentiation [Term] id: GO:0045605 name: negative regulation of epidermal cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "down regulation of epidermal cell differentiation" EXACT [] synonym: "down-regulation of epidermal cell differentiation" EXACT [] synonym: "downregulation of epidermal cell differentiation" EXACT [] synonym: "inhibition of epidermal cell differentiation" NARROW [] synonym: "negative regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045683 ! negative regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009913 ! negatively regulates epidermal cell differentiation relationship: RO:0002212 GO:0009913 ! negatively regulates epidermal cell differentiation [Term] id: GO:0045606 name: positive regulation of epidermal cell differentiation def: "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "activation of epidermal cell differentiation" NARROW [] synonym: "positive regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] synonym: "stimulation of epidermal cell differentiation" NARROW [] synonym: "up regulation of epidermal cell differentiation" EXACT [] synonym: "up-regulation of epidermal cell differentiation" EXACT [] synonym: "upregulation of epidermal cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045684 ! positive regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009913 ! positively regulates epidermal cell differentiation relationship: RO:0002213 GO:0009913 ! positively regulates epidermal cell differentiation [Term] id: GO:0045619 name: regulation of lymphocyte differentiation def: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "regulation of lymphocyte development" RELATED [GOC:add] is_a: GO:0051249 ! regulation of lymphocyte activation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030098 ! regulates lymphocyte differentiation relationship: RO:0002211 GO:0030098 ! regulates lymphocyte differentiation [Term] id: GO:0045620 name: negative regulation of lymphocyte differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "down regulation of lymphocyte differentiation" EXACT [] synonym: "down-regulation of lymphocyte differentiation" EXACT [] synonym: "downregulation of lymphocyte differentiation" EXACT [] synonym: "inhibition of lymphocyte differentiation" NARROW [] synonym: "negative regulation of lymphocyte development" RELATED [GOC:add] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030098 ! negatively regulates lymphocyte differentiation relationship: RO:0002212 GO:0030098 ! negatively regulates lymphocyte differentiation [Term] id: GO:0045621 name: positive regulation of lymphocyte differentiation def: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "activation of lymphocyte differentiation" NARROW [] synonym: "positive regulation of lymphocyte development" RELATED [GOC:add] synonym: "stimulation of lymphocyte differentiation" NARROW [] synonym: "up regulation of lymphocyte differentiation" EXACT [] synonym: "up-regulation of lymphocyte differentiation" EXACT [] synonym: "upregulation of lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030098 ! positively regulates lymphocyte differentiation relationship: RO:0002213 GO:0030098 ! positively regulates lymphocyte differentiation [Term] id: GO:0045637 name: regulation of myeloid cell differentiation def: "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] xref: Reactome:R-HSA-8939246 "RUNX1 regulates transcription of genes involved in differentiation of myeloid cells" is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030099 ! regulates myeloid cell differentiation relationship: RO:0002211 GO:0030099 ! regulates myeloid cell differentiation [Term] id: GO:0045638 name: negative regulation of myeloid cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "down regulation of myeloid cell differentiation" EXACT [] synonym: "down-regulation of myeloid cell differentiation" EXACT [] synonym: "downregulation of myeloid cell differentiation" EXACT [] synonym: "inhibition of myeloid cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030099 ! negatively regulates myeloid cell differentiation relationship: RO:0002212 GO:0030099 ! negatively regulates myeloid cell differentiation [Term] id: GO:0045639 name: positive regulation of myeloid cell differentiation def: "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "activation of myeloid cell differentiation" NARROW [] synonym: "stimulation of myeloid cell differentiation" NARROW [] synonym: "up regulation of myeloid cell differentiation" EXACT [] synonym: "up-regulation of myeloid cell differentiation" EXACT [] synonym: "upregulation of myeloid cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030099 ! positively regulates myeloid cell differentiation relationship: RO:0002213 GO:0030099 ! positively regulates myeloid cell differentiation [Term] id: GO:0045646 name: regulation of erythrocyte differentiation def: "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "regulation of RBC differentiation" EXACT [CL:0000232] synonym: "regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030218 ! regulates erythrocyte differentiation relationship: RO:0002211 GO:0030218 ! regulates erythrocyte differentiation [Term] id: GO:0045647 name: negative regulation of erythrocyte differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "down regulation of erythrocyte differentiation" EXACT [] synonym: "down-regulation of erythrocyte differentiation" EXACT [] synonym: "downregulation of erythrocyte differentiation" EXACT [] synonym: "inhibition of erythrocyte differentiation" NARROW [] synonym: "negative regulation of RBC differentiation" EXACT [CL:0000232] synonym: "negative regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030218 ! negatively regulates erythrocyte differentiation relationship: RO:0002212 GO:0030218 ! negatively regulates erythrocyte differentiation [Term] id: GO:0045648 name: positive regulation of erythrocyte differentiation def: "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "activation of erythrocyte differentiation" NARROW [] synonym: "positive regulation of RBC differentiation" EXACT [CL:0000232] synonym: "positive regulation of red blood cell differentiation" EXACT [CL:0000232] synonym: "stimulation of erythrocyte differentiation" NARROW [] synonym: "up regulation of erythrocyte differentiation" EXACT [] synonym: "up-regulation of erythrocyte differentiation" EXACT [] synonym: "upregulation of erythrocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030218 ! positively regulates erythrocyte differentiation relationship: RO:0002213 GO:0030218 ! positively regulates erythrocyte differentiation [Term] id: GO:0045652 name: regulation of megakaryocyte differentiation def: "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] xref: Reactome:R-HSA-8936459 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030219 ! regulates megakaryocyte differentiation relationship: RO:0002211 GO:0030219 ! regulates megakaryocyte differentiation [Term] id: GO:0045653 name: negative regulation of megakaryocyte differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "down regulation of megakaryocyte differentiation" EXACT [] synonym: "down-regulation of megakaryocyte differentiation" EXACT [] synonym: "downregulation of megakaryocyte differentiation" EXACT [] synonym: "inhibition of megakaryocyte differentiation" NARROW [] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030219 ! negatively regulates megakaryocyte differentiation relationship: RO:0002212 GO:0030219 ! negatively regulates megakaryocyte differentiation [Term] id: GO:0045654 name: positive regulation of megakaryocyte differentiation def: "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "activation of megakaryocyte differentiation" NARROW [] synonym: "stimulation of megakaryocyte differentiation" NARROW [] synonym: "up regulation of megakaryocyte differentiation" EXACT [] synonym: "up-regulation of megakaryocyte differentiation" EXACT [] synonym: "upregulation of megakaryocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030219 ! positively regulates megakaryocyte differentiation relationship: RO:0002213 GO:0030219 ! positively regulates megakaryocyte differentiation [Term] id: GO:0045661 name: regulation of myoblast differentiation def: "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045445 ! regulates myoblast differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0045445 ! regulates myoblast differentiation [Term] id: GO:0045662 name: negative regulation of myoblast differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "down regulation of myoblast differentiation" EXACT [] synonym: "down-regulation of myoblast differentiation" EXACT [] synonym: "downregulation of myoblast differentiation" EXACT [] synonym: "inhibition of myoblast differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045445 ! negatively regulates myoblast differentiation relationship: RO:0002212 GO:0045445 ! negatively regulates myoblast differentiation [Term] id: GO:0045663 name: positive regulation of myoblast differentiation def: "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "activation of myoblast differentiation" NARROW [] synonym: "stimulation of myoblast differentiation" NARROW [] synonym: "up regulation of myoblast differentiation" EXACT [] synonym: "up-regulation of myoblast differentiation" EXACT [] synonym: "upregulation of myoblast differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045445 ! positively regulates myoblast differentiation relationship: RO:0002213 GO:0045445 ! positively regulates myoblast differentiation [Term] id: GO:0045664 name: regulation of neuron differentiation def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030182 ! regulates neuron differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0030182 ! regulates neuron differentiation [Term] id: GO:0045665 name: negative regulation of neuron differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "down regulation of neuron differentiation" EXACT [] synonym: "down-regulation of neuron differentiation" EXACT [] synonym: "downregulation of neuron differentiation" EXACT [] synonym: "inhibition of neuron differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030182 ! negatively regulates neuron differentiation relationship: RO:0002212 GO:0030182 ! negatively regulates neuron differentiation [Term] id: GO:0045666 name: positive regulation of neuron differentiation def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "activation of neuron differentiation" NARROW [] synonym: "stimulation of neuron differentiation" NARROW [] synonym: "up regulation of neuron differentiation" EXACT [] synonym: "up-regulation of neuron differentiation" EXACT [] synonym: "upregulation of neuron differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030182 ! positively regulates neuron differentiation relationship: RO:0002213 GO:0030182 ! positively regulates neuron differentiation [Term] id: GO:0045682 name: regulation of epidermis development def: "Any process that modulates the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "regulation of epidermal development" EXACT [] synonym: "regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008544 ! regulates epidermis development relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0008544 ! regulates epidermis development property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0045683 name: negative regulation of epidermis development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "down regulation of epidermis development" EXACT [] synonym: "down-regulation of epidermis development" EXACT [] synonym: "downregulation of epidermis development" EXACT [] synonym: "inhibition of epidermis development" NARROW [] synonym: "negative regulation of epidermal development" EXACT [] synonym: "negative regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008544 ! negatively regulates epidermis development relationship: RO:0002212 GO:0008544 ! negatively regulates epidermis development property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0045684 name: positive regulation of epidermis development def: "Any process that activates or increases the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "activation of epidermis development" NARROW [] synonym: "positive regulation of epidermal development" EXACT [] synonym: "positive regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] synonym: "stimulation of epidermis development" NARROW [] synonym: "up regulation of epidermis development" EXACT [] synonym: "up-regulation of epidermis development" EXACT [] synonym: "upregulation of epidermis development" EXACT [] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008544 ! positively regulates epidermis development relationship: RO:0002213 GO:0008544 ! positively regulates epidermis development property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0045685 name: regulation of glial cell differentiation def: "Any process that modulates the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "regulation of glia cell differentiation" EXACT [] synonym: "regulation of neuroglia differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010001 ! regulates glial cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0010001 ! regulates glial cell differentiation [Term] id: GO:0045686 name: negative regulation of glial cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "down regulation of glial cell differentiation" EXACT [] synonym: "down-regulation of glial cell differentiation" EXACT [] synonym: "downregulation of glial cell differentiation" EXACT [] synonym: "inhibition of glial cell differentiation" NARROW [] synonym: "negative regulation of glia cell differentiation" EXACT [] synonym: "negative regulation of neuroglia differentiation" EXACT [] is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010001 ! negatively regulates glial cell differentiation relationship: RO:0002212 GO:0010001 ! negatively regulates glial cell differentiation [Term] id: GO:0045687 name: positive regulation of glial cell differentiation def: "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "activation of glial cell differentiation" NARROW [] synonym: "positive regulation of glia cell differentiation" EXACT [] synonym: "positive regulation of neuroglia differentiation" EXACT [] synonym: "stimulation of glial cell differentiation" NARROW [] synonym: "up regulation of glial cell differentiation" EXACT [] synonym: "up-regulation of glial cell differentiation" EXACT [] synonym: "upregulation of glial cell differentiation" EXACT [] is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010001 ! positively regulates glial cell differentiation relationship: RO:0002213 GO:0010001 ! positively regulates glial cell differentiation [Term] id: GO:0045700 name: regulation of spermatid nuclear differentiation def: "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903353 ! regulation of nucleus organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007289 ! regulates spermatid nucleus differentiation relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0007289 ! regulates spermatid nucleus differentiation property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0045701 name: negative regulation of spermatid nuclear differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "down regulation of spermatid nuclear differentiation" EXACT [] synonym: "down-regulation of spermatid nuclear differentiation" EXACT [] synonym: "downregulation of spermatid nuclear differentiation" EXACT [] synonym: "inhibition of spermatid nuclear differentiation" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007289 ! negatively regulates spermatid nucleus differentiation relationship: RO:0002212 GO:0007289 ! negatively regulates spermatid nucleus differentiation property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0045702 name: positive regulation of spermatid nuclear differentiation def: "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "activation of spermatid nuclear differentiation" NARROW [] synonym: "stimulation of spermatid nuclear differentiation" NARROW [] synonym: "up regulation of spermatid nuclear differentiation" EXACT [] synonym: "up-regulation of spermatid nuclear differentiation" EXACT [] synonym: "upregulation of spermatid nuclear differentiation" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007289 ! positively regulates spermatid nucleus differentiation relationship: RO:0002213 GO:0007289 ! positively regulates spermatid nucleus differentiation property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0045719 name: negative regulation of glycogen biosynthetic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen biosynthetic process" EXACT [] synonym: "down-regulation of glycogen biosynthetic process" EXACT [] synonym: "downregulation of glycogen biosynthetic process" EXACT [] synonym: "inhibition of glycogen biosynthetic process" NARROW [] synonym: "negative regulation of glycogen anabolism" EXACT [] synonym: "negative regulation of glycogen biosynthesis" EXACT [] synonym: "negative regulation of glycogen formation" EXACT [] synonym: "negative regulation of glycogen synthesis" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005978 ! negatively regulates glycogen biosynthetic process relationship: RO:0002212 GO:0005978 ! negatively regulates glycogen biosynthetic process [Term] id: GO:0045721 name: negative regulation of gluconeogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "down regulation of gluconeogenesis" EXACT [] synonym: "down-regulation of gluconeogenesis" EXACT [] synonym: "downregulation of gluconeogenesis" EXACT [] synonym: "inhibition of gluconeogenesis" NARROW [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006094 ! negatively regulates gluconeogenesis relationship: RO:0002212 GO:0006094 ! negatively regulates gluconeogenesis [Term] id: GO:0045722 name: positive regulation of gluconeogenesis def: "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "activation of gluconeogenesis" NARROW [] synonym: "stimulation of gluconeogenesis" NARROW [] synonym: "up regulation of gluconeogenesis" EXACT [] synonym: "up-regulation of gluconeogenesis" EXACT [] synonym: "upregulation of gluconeogenesis" EXACT [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0010907 ! positive regulation of glucose metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006094 ! positively regulates gluconeogenesis relationship: RO:0002213 GO:0006094 ! positively regulates gluconeogenesis [Term] id: GO:0045724 name: positive regulation of cilium assembly def: "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." [GOC:cilia, GOC:go_curators] synonym: "activation of cilium assembly" NARROW [] synonym: "positive regulation of flagellum assembly" BROAD [] synonym: "positive regulation of flagellum biogenesis" RELATED [GOC:mah] synonym: "stimulation of cilium assembly" NARROW [] synonym: "up regulation of cilium assembly" EXACT [] synonym: "up-regulation of cilium assembly" EXACT [] synonym: "upregulation of cilium assembly" EXACT [] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902117 ! positive regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060271 ! positively regulates cilium assembly relationship: RO:0002213 GO:0060271 ! positively regulates cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0045725 name: positive regulation of glycogen biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "activation of glycogen biosynthetic process" NARROW [] synonym: "positive regulation of glycogen anabolism" EXACT [] synonym: "positive regulation of glycogen biosynthesis" EXACT [] synonym: "positive regulation of glycogen formation" EXACT [] synonym: "positive regulation of glycogen synthesis" EXACT [] synonym: "stimulation of glycogen biosynthetic process" NARROW [] synonym: "up regulation of glycogen biosynthetic process" EXACT [] synonym: "up-regulation of glycogen biosynthetic process" EXACT [] synonym: "upregulation of glycogen biosynthetic process" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005978 ! positively regulates glycogen biosynthetic process relationship: RO:0002213 GO:0005978 ! positively regulates glycogen biosynthetic process [Term] id: GO:0045727 name: positive regulation of translation alt_id: GO:0045946 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of protein biosynthetic process" NARROW [] synonym: "positive regulation of protein anabolism" EXACT [] synonym: "positive regulation of protein biosynthesis" EXACT [] synonym: "positive regulation of protein biosynthetic process" EXACT [GOC:tb] synonym: "positive regulation of protein formation" EXACT [] synonym: "positive regulation of protein synthesis" EXACT [] synonym: "stimulation of protein biosynthetic process" NARROW [] synonym: "up regulation of protein biosynthetic process" EXACT [] synonym: "up-regulation of protein biosynthetic process" EXACT [] synonym: "upregulation of protein biosynthetic process" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006412 ! positively regulates translation relationship: RO:0002213 GO:0006412 ! positively regulates translation [Term] id: GO:0045732 name: positive regulation of protein catabolic process alt_id: GO:1903364 alt_id: GO:2000600 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators] synonym: "activation of cellular protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of cellular protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of cellular protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of cellular protein degradation" NARROW [GOC:TermGenie] synonym: "activation of protein catabolic process" NARROW [] synonym: "positive regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein catabolic process" EXACT [] synonym: "positive regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of cyclin breakdown" NARROW [GOC:obol] synonym: "positive regulation of cyclin catabolic process" NARROW [] synonym: "positive regulation of cyclin catabolism" NARROW [GOC:obol] synonym: "positive regulation of cyclin degradation" NARROW [GOC:obol] synonym: "positive regulation of degradation of cyclin" NARROW [GOC:obol] synonym: "positive regulation of protein breakdown" EXACT [] synonym: "positive regulation of protein catabolism" EXACT [] synonym: "positive regulation of protein degradation" EXACT [] synonym: "stimulation of protein catabolic process" NARROW [] synonym: "up regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein catabolic process" EXACT [] synonym: "up-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein catabolic process" EXACT [] synonym: "upregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030163 ! positively regulates protein catabolic process relationship: RO:0002213 GO:0030163 ! positively regulates protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0045733 name: acetate catabolic process alt_id: GO:0019663 def: "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate breakdown" EXACT [] synonym: "acetate catabolism" EXACT [] synonym: "acetate degradation" EXACT [] synonym: "homoacetate catabolic process" RELATED [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate relationship: RO:0004009 CHEBI:30089 ! has primary input acetate [Term] id: GO:0045734 name: regulation of acetate catabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "regulation of acetate breakdown" EXACT [] synonym: "regulation of acetate catabolism" EXACT [] synonym: "regulation of acetate degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0010565 ! regulation of ketone metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045733 ! regulates acetate catabolic process relationship: RO:0002211 GO:0045733 ! regulates acetate catabolic process [Term] id: GO:0045753 name: negative regulation of acetate catabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "down regulation of acetate catabolic process" EXACT [] synonym: "down-regulation of acetate catabolic process" EXACT [] synonym: "downregulation of acetate catabolic process" EXACT [] synonym: "inhibition of acetate catabolic process" NARROW [] synonym: "negative regulation of acetate breakdown" EXACT [] synonym: "negative regulation of acetate catabolism" EXACT [] synonym: "negative regulation of acetate degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045733 ! negatively regulates acetate catabolic process relationship: RO:0002212 GO:0045733 ! negatively regulates acetate catabolic process [Term] id: GO:0045754 name: positive regulation of acetate catabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "activation of acetate catabolic process" NARROW [] synonym: "positive regulation of acetate breakdown" EXACT [] synonym: "positive regulation of acetate catabolism" EXACT [] synonym: "positive regulation of acetate degradation" EXACT [] synonym: "stimulation of acetate catabolic process" NARROW [] synonym: "up regulation of acetate catabolic process" EXACT [] synonym: "up-regulation of acetate catabolic process" EXACT [] synonym: "upregulation of acetate catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045733 ! positively regulates acetate catabolic process relationship: RO:0002213 GO:0045733 ! positively regulates acetate catabolic process [Term] id: GO:0045759 name: negative regulation of action potential def: "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "down regulation of action potential" EXACT [] synonym: "down-regulation of action potential" EXACT [] synonym: "downregulation of action potential" EXACT [] synonym: "inhibition of action potential" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001508 ! negatively regulates action potential relationship: RO:0002212 GO:0001508 ! negatively regulates action potential property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0045760 name: positive regulation of action potential def: "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "activation of action potential" NARROW [] synonym: "stimulation of action potential" NARROW [] synonym: "up regulation of action potential" EXACT [] synonym: "up-regulation of action potential" EXACT [] synonym: "upregulation of action potential" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001508 ! positively regulates action potential relationship: RO:0002213 GO:0001508 ! positively regulates action potential property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0045763 name: negative regulation of amino acid metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "down regulation of amino acid metabolic process" EXACT [] synonym: "down-regulation of amino acid metabolic process" EXACT [] synonym: "downregulation of amino acid metabolic process" EXACT [] synonym: "inhibition of amino acid metabolic process" NARROW [] synonym: "negative regulation of amino acid metabolism" EXACT [] is_a: GO:0006521 ! regulation of amino acid metabolic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006520 ! negatively regulates amino acid metabolic process relationship: RO:0002212 GO:0006520 ! negatively regulates amino acid metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] id: GO:0045764 name: positive regulation of amino acid metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "activation of amino acid metabolic process" NARROW [] synonym: "positive regulation of amino acid metabolism" EXACT [] synonym: "positive regulation of cellular amino acid metabolic process" EXACT [] synonym: "stimulation of amino acid metabolic process" NARROW [] synonym: "up regulation of amino acid metabolic process" EXACT [] synonym: "up-regulation of amino acid metabolic process" EXACT [] synonym: "upregulation of amino acid metabolic process" EXACT [] is_a: GO:0006521 ! regulation of amino acid metabolic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006520 ! positively regulates amino acid metabolic process relationship: RO:0002213 GO:0006520 ! positively regulates amino acid metabolic process [Term] id: GO:0045765 name: regulation of angiogenesis def: "Any process that modulates the frequency, rate or extent of angiogenesis." [GOC:go_curators] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001525 ! regulates angiogenesis relationship: RO:0002211 GO:0001525 ! regulates angiogenesis [Term] id: GO:0045766 name: positive regulation of angiogenesis def: "Any process that activates or increases angiogenesis." [GOC:go_curators] synonym: "activation of angiogenesis" NARROW [] synonym: "stimulation of angiogenesis" NARROW [] synonym: "up regulation of angiogenesis" EXACT [] synonym: "up-regulation of angiogenesis" EXACT [] synonym: "upregulation of angiogenesis" EXACT [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:1904018 ! positive regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001525 ! positively regulates angiogenesis relationship: RO:0002213 GO:0001525 ! positively regulates angiogenesis [Term] id: GO:0045769 name: negative regulation of asymmetric cell division def: "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "down regulation of asymmetric cell division" EXACT [] synonym: "down-regulation of asymmetric cell division" EXACT [] synonym: "downregulation of asymmetric cell division" EXACT [] synonym: "inhibition of asymmetric cell division" NARROW [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051782 ! negative regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008356 ! negatively regulates asymmetric cell division relationship: RO:0002212 GO:0008356 ! negatively regulates asymmetric cell division [Term] id: GO:0045770 name: positive regulation of asymmetric cell division def: "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "activation of asymmetric cell division" NARROW [] synonym: "stimulation of asymmetric cell division" NARROW [] synonym: "up regulation of asymmetric cell division" EXACT [] synonym: "up-regulation of asymmetric cell division" EXACT [] synonym: "upregulation of asymmetric cell division" EXACT [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051781 ! positive regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008356 ! positively regulates asymmetric cell division relationship: RO:0002213 GO:0008356 ! positively regulates asymmetric cell division [Term] id: GO:0045778 name: positive regulation of ossification def: "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "activation of ossification" NARROW [] synonym: "positive regulation of bone biosynthesis" EXACT [] synonym: "positive regulation of bone formation" EXACT [] synonym: "stimulation of ossification" NARROW [] synonym: "up regulation of ossification" EXACT [] synonym: "up-regulation of ossification" EXACT [] synonym: "upregulation of ossification" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001503 ! positively regulates ossification relationship: RO:0002213 GO:0001503 ! positively regulates ossification [Term] id: GO:0045785 name: positive regulation of cell adhesion def: "Any process that activates or increases the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "activation of cell adhesion" NARROW [] synonym: "stimulation of cell adhesion" NARROW [] synonym: "up regulation of cell adhesion" EXACT [] synonym: "up-regulation of cell adhesion" EXACT [] synonym: "upregulation of cell adhesion" EXACT [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007155 ! positively regulates cell adhesion relationship: RO:0002213 GO:0007155 ! positively regulates cell adhesion [Term] id: GO:0045786 name: negative regulation of cell cycle def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through cell cycle" EXACT [] synonym: "down-regulation of progression through cell cycle" EXACT [] synonym: "downregulation of progression through cell cycle" EXACT [] synonym: "inhibition of progression through cell cycle" NARROW [] synonym: "negative regulation of cell cycle progression" EXACT [] synonym: "negative regulation of progression through cell cycle" EXACT [] xref: Reactome:R-HSA-193670 "p75NTR negatively regulates cell cycle via SC1" is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007049 ! negatively regulates cell cycle relationship: RO:0002212 GO:0007049 ! negatively regulates cell cycle [Term] id: GO:0045787 name: positive regulation of cell cycle def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators] synonym: "activation of progression through cell cycle" NARROW [] synonym: "positive regulation of cell cycle progression" EXACT [] synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through cell cycle" NARROW [] synonym: "up regulation of progression through cell cycle" EXACT [] synonym: "up-regulation of progression through cell cycle" EXACT [] synonym: "upregulation of progression through cell cycle" EXACT [] xref: Reactome:R-HSA-8849470 "PTK6 Regulates Cell Cycle" is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007049 ! positively regulates cell cycle relationship: RO:0002213 GO:0007049 ! positively regulates cell cycle [Term] id: GO:0045806 name: negative regulation of endocytosis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "down regulation of endocytosis" EXACT [] synonym: "down-regulation of endocytosis" EXACT [] synonym: "downregulation of endocytosis" EXACT [] synonym: "inhibition of endocytosis" NARROW [] is_a: GO:0030100 ! regulation of endocytosis is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006897 ! negatively regulates endocytosis relationship: RO:0002212 GO:0006897 ! negatively regulates endocytosis [Term] id: GO:0045807 name: positive regulation of endocytosis def: "Any process that activates or increases the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "activation of endocytosis" NARROW [] synonym: "stimulation of endocytosis" NARROW [] synonym: "up regulation of endocytosis" EXACT [] synonym: "up-regulation of endocytosis" EXACT [] synonym: "upregulation of endocytosis" EXACT [] is_a: GO:0030100 ! regulation of endocytosis is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006897 ! positively regulates endocytosis relationship: RO:0002213 GO:0006897 ! positively regulates endocytosis [Term] id: GO:0045814 name: negative regulation of gene expression, epigenetic def: "An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation." [PMID:22243696] synonym: "down regulation of gene expression, epigenetic" EXACT [] synonym: "down-regulation of gene expression, epigenetic" EXACT [] synonym: "downregulation of gene expression, epigenetic" EXACT [] synonym: "gene silencing" RELATED [] synonym: "inhibition of gene expression, epigenetic" NARROW [] xref: Reactome:R-HSA-212300 "PRC2 methylates histones and DNA" xref: Reactome:R-HSA-5250941 "Negative epigenetic regulation of rRNA expression" is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0040029 ! epigenetic regulation of gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22201" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30601" xsd:anyURI [Term] id: GO:0045818 name: negative regulation of glycogen catabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen catabolic process" EXACT [] synonym: "down-regulation of glycogen catabolic process" EXACT [] synonym: "downregulation of glycogen catabolic process" EXACT [] synonym: "inhibition of glycogen catabolic process" NARROW [] synonym: "negative regulation of glycogen breakdown" EXACT [] synonym: "negative regulation of glycogen catabolism" EXACT [] synonym: "negative regulation of glycogen degradation" EXACT [] synonym: "negative regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005980 ! negatively regulates glycogen catabolic process relationship: RO:0002212 GO:0005980 ! negatively regulates glycogen catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29024" xsd:anyURI [Term] id: GO:0045819 name: positive regulation of glycogen catabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "activation of glycogen catabolic process" NARROW [] synonym: "positive regulation of glycogen breakdown" EXACT [] synonym: "positive regulation of glycogen catabolism" EXACT [] synonym: "positive regulation of glycogen degradation" EXACT [] synonym: "positive regulation of glycogenolysis" EXACT [GOC:sl] synonym: "stimulation of glycogen catabolic process" NARROW [] synonym: "up regulation of glycogen catabolic process" EXACT [] synonym: "up-regulation of glycogen catabolic process" EXACT [] synonym: "upregulation of glycogen catabolic process" EXACT [] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005980 ! positively regulates glycogen catabolic process relationship: RO:0002213 GO:0005980 ! positively regulates glycogen catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29024" xsd:anyURI [Term] id: GO:0045822 name: negative regulation of heart contraction def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "down regulation of heart contraction" EXACT [] synonym: "down-regulation of heart contraction" EXACT [] synonym: "downregulation of heart contraction" EXACT [] synonym: "inhibition of heart contraction" NARROW [] synonym: "negative regulation of cardiac contraction" RELATED [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903523 ! negative regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060047 ! negatively regulates heart contraction relationship: RO:0002212 GO:0060047 ! negatively regulates heart contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045823 name: positive regulation of heart contraction def: "Any process that activates or increases the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "activation of heart contraction" NARROW [] synonym: "positive regulation of cardiac contraction" EXACT [] synonym: "stimulation of heart contraction" NARROW [] synonym: "up regulation of heart contraction" EXACT [] synonym: "up-regulation of heart contraction" EXACT [] synonym: "upregulation of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903524 ! positive regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060047 ! positively regulates heart contraction relationship: RO:0002213 GO:0060047 ! positively regulates heart contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045833 name: negative regulation of lipid metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "down regulation of lipid metabolic process" EXACT [] synonym: "down-regulation of lipid metabolic process" EXACT [] synonym: "downregulation of lipid metabolic process" EXACT [] synonym: "inhibition of lipid metabolic process" NARROW [] synonym: "negative regulation of lipid metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006629 ! negatively regulates lipid metabolic process relationship: RO:0002212 GO:0006629 ! negatively regulates lipid metabolic process [Term] id: GO:0045834 name: positive regulation of lipid metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "activation of lipid metabolic process" NARROW [] synonym: "positive regulation of lipid metabolism" EXACT [] synonym: "stimulation of lipid metabolic process" NARROW [] synonym: "up regulation of lipid metabolic process" EXACT [] synonym: "up-regulation of lipid metabolic process" EXACT [] synonym: "upregulation of lipid metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006629 ! positively regulates lipid metabolic process relationship: RO:0002213 GO:0006629 ! positively regulates lipid metabolic process [Term] id: GO:0045835 name: negative regulation of meiotic nuclear division def: "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "down regulation of meiosis" EXACT [] synonym: "down-regulation of meiosis" EXACT [] synonym: "downregulation of meiosis" EXACT [] synonym: "inhibition of meiosis" NARROW [] synonym: "negative regulation of meiosis" EXACT [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0140013 ! negatively regulates meiotic nuclear division relationship: RO:0002212 GO:0140013 ! negatively regulates meiotic nuclear division [Term] id: GO:0045836 name: positive regulation of meiotic nuclear division def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "activation of meiosis" NARROW [] synonym: "positive regulation of meiosis" EXACT [] synonym: "stimulation of meiosis" NARROW [] synonym: "up regulation of meiosis" EXACT [] synonym: "up-regulation of meiosis" EXACT [] synonym: "upregulation of meiosis" EXACT [] is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0140013 ! positively regulates meiotic nuclear division relationship: RO:0002213 GO:0140013 ! positively regulates meiotic nuclear division [Term] id: GO:0045839 name: negative regulation of mitotic nuclear division def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of mitosis" EXACT [] synonym: "down-regulation of mitosis" EXACT [] synonym: "downregulation of mitosis" EXACT [] synonym: "inhibition of mitosis" NARROW [] synonym: "negative regulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0045930 ! negative regulation of mitotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0140014 ! negatively regulates mitotic nuclear division relationship: RO:0002212 GO:0140014 ! negatively regulates mitotic nuclear division [Term] id: GO:0045840 name: positive regulation of mitotic nuclear division def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "activation of mitosis" NARROW [] synonym: "mitogenic activity" NARROW [] synonym: "positive regulation of mitosis" EXACT [] synonym: "stimulation of mitosis" NARROW [] synonym: "up regulation of mitosis" EXACT [] synonym: "up-regulation of mitosis" EXACT [] synonym: "upregulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0140014 ! positively regulates mitotic nuclear division relationship: RO:0002213 GO:0140014 ! positively regulates mitotic nuclear division [Term] id: GO:0045843 name: negative regulation of striated muscle tissue development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "down regulation of striated muscle development" EXACT [] synonym: "down-regulation of striated muscle development" EXACT [] synonym: "downregulation of striated muscle development" EXACT [] synonym: "inhibition of striated muscle development" NARROW [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048635 ! negative regulation of muscle organ development is_a: GO:1901862 ! negative regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014706 ! negatively regulates striated muscle tissue development relationship: RO:0002212 GO:0014706 ! negatively regulates striated muscle tissue development [Term] id: GO:0045844 name: positive regulation of striated muscle tissue development def: "Any process that activates or increases the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "activation of striated muscle development" NARROW [] synonym: "stimulation of striated muscle development" NARROW [] synonym: "up regulation of striated muscle development" EXACT [] synonym: "up-regulation of striated muscle development" EXACT [] synonym: "upregulation of striated muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048636 ! positive regulation of muscle organ development is_a: GO:1901863 ! positive regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014706 ! positively regulates striated muscle tissue development relationship: RO:0002213 GO:0014706 ! positively regulates striated muscle tissue development [Term] id: GO:0045900 name: negative regulation of translational elongation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "down regulation of translational elongation" EXACT [] synonym: "down-regulation of translational elongation" EXACT [] synonym: "downregulation of translational elongation" EXACT [] synonym: "inhibition of translational elongation" NARROW [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006414 ! negatively regulates translational elongation relationship: RO:0002212 GO:0006414 ! negatively regulates translational elongation [Term] id: GO:0045901 name: positive regulation of translational elongation def: "Any process that activates or increases the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "activation of translational elongation" NARROW [] synonym: "stimulation of translational elongation" NARROW [] synonym: "up regulation of translational elongation" EXACT [] synonym: "up-regulation of translational elongation" EXACT [] synonym: "upregulation of translational elongation" EXACT [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006414 ! positively regulates translational elongation relationship: RO:0002213 GO:0006414 ! positively regulates translational elongation [Term] id: GO:0045904 name: negative regulation of translational termination def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "down regulation of translational termination" EXACT [] synonym: "down-regulation of translational termination" EXACT [] synonym: "downregulation of translational termination" EXACT [] synonym: "inhibition of translational termination" NARROW [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0017148 ! negative regulation of translation is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006415 ! negatively regulates translational termination relationship: RO:0002212 GO:0006415 ! negatively regulates translational termination [Term] id: GO:0045905 name: positive regulation of translational termination def: "Any process that activates or increases the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "activation of translational termination" NARROW [] synonym: "stimulation of translational termination" NARROW [] synonym: "up regulation of translational termination" EXACT [] synonym: "up-regulation of translational termination" EXACT [] synonym: "upregulation of translational termination" EXACT [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006415 ! positively regulates translational termination relationship: RO:0002213 GO:0006415 ! positively regulates translational termination [Term] id: GO:0045912 name: negative regulation of carbohydrate metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "down regulation of carbohydrate metabolic process" EXACT [] synonym: "down-regulation of carbohydrate metabolic process" EXACT [] synonym: "downregulation of carbohydrate metabolic process" EXACT [] synonym: "inhibition of carbohydrate metabolic process" NARROW [] synonym: "negative regulation of carbohydrate metabolism" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005975 ! negatively regulates carbohydrate metabolic process relationship: RO:0002212 GO:0005975 ! negatively regulates carbohydrate metabolic process [Term] id: GO:0045913 name: positive regulation of carbohydrate metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "activation of carbohydrate metabolic process" NARROW [] synonym: "positive regulation of carbohydrate metabolism" EXACT [] synonym: "stimulation of carbohydrate metabolic process" NARROW [] synonym: "up regulation of carbohydrate metabolic process" EXACT [] synonym: "up-regulation of carbohydrate metabolic process" EXACT [] synonym: "upregulation of carbohydrate metabolic process" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005975 ! positively regulates carbohydrate metabolic process relationship: RO:0002213 GO:0005975 ! positively regulates carbohydrate metabolic process [Term] id: GO:0045920 name: negative regulation of exocytosis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "down regulation of exocytosis" EXACT [] synonym: "down-regulation of exocytosis" EXACT [] synonym: "downregulation of exocytosis" EXACT [] synonym: "inhibition of exocytosis" NARROW [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006887 ! negatively regulates exocytosis relationship: RO:0002212 GO:0006887 ! negatively regulates exocytosis [Term] id: GO:0045921 name: positive regulation of exocytosis def: "Any process that activates or increases the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "activation of exocytosis" NARROW [] synonym: "stimulation of exocytosis" NARROW [] synonym: "up regulation of exocytosis" EXACT [] synonym: "up-regulation of exocytosis" EXACT [] synonym: "upregulation of exocytosis" EXACT [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006887 ! positively regulates exocytosis relationship: RO:0002213 GO:0006887 ! positively regulates exocytosis [Term] id: GO:0045926 name: negative regulation of growth def: "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "down regulation of growth" EXACT [] synonym: "down-regulation of growth" EXACT [] synonym: "downregulation of growth" EXACT [] synonym: "inhibition of growth" NARROW [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0040007 ! negatively regulates growth relationship: RO:0002212 GO:0040007 ! negatively regulates growth [Term] id: GO:0045927 name: positive regulation of growth def: "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "activation of growth" NARROW [] synonym: "stimulation of growth" NARROW [] synonym: "up regulation of growth" EXACT [] synonym: "up-regulation of growth" EXACT [] synonym: "upregulation of growth" EXACT [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0040007 ! positively regulates growth relationship: RO:0002213 GO:0040007 ! positively regulates growth [Term] id: GO:0045930 name: negative regulation of mitotic cell cycle def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through mitotic cell cycle" EXACT [] synonym: "downregulation of progression through mitotic cell cycle" EXACT [] synonym: "inhibition of progression through mitotic cell cycle" NARROW [] synonym: "negative regulation of mitotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: Reactome:R-HSA-8854050 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000278 ! negatively regulates mitotic cell cycle relationship: RO:0002212 GO:0000278 ! negatively regulates mitotic cell cycle [Term] id: GO:0045931 name: positive regulation of mitotic cell cycle def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of progression through mitotic cell cycle" NARROW [] synonym: "positive regulation of mitotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through mitotic cell cycle" NARROW [] synonym: "up regulation of progression through mitotic cell cycle" EXACT [] synonym: "up-regulation of progression through mitotic cell cycle" EXACT [] synonym: "upregulation of progression through mitotic cell cycle" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000278 ! positively regulates mitotic cell cycle relationship: RO:0002213 GO:0000278 ! positively regulates mitotic cell cycle [Term] id: GO:0045932 name: negative regulation of muscle contraction def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "down regulation of muscle contraction" EXACT [] synonym: "down-regulation of muscle contraction" EXACT [] synonym: "downregulation of muscle contraction" EXACT [] synonym: "inhibition of muscle contraction" NARROW [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006936 ! negatively regulates muscle contraction relationship: RO:0002212 GO:0006936 ! negatively regulates muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045933 name: positive regulation of muscle contraction def: "Any process that activates or increases the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "activation of muscle contraction" NARROW [] synonym: "stimulation of muscle contraction" NARROW [] synonym: "up regulation of muscle contraction" EXACT [] synonym: "up-regulation of muscle contraction" EXACT [] synonym: "upregulation of muscle contraction" EXACT [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006936 ! positively regulates muscle contraction relationship: RO:0002213 GO:0006936 ! positively regulates muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045934 name: negative regulation of nucleobase-containing compound metabolic process def: "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006139 ! negatively regulates nucleobase-containing compound metabolic process relationship: RO:0002212 GO:0006139 ! negatively regulates nucleobase-containing compound metabolic process [Term] id: GO:0045939 name: negative regulation of steroid metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "down regulation of steroid metabolic process" EXACT [] synonym: "down-regulation of steroid metabolic process" EXACT [] synonym: "downregulation of steroid metabolic process" EXACT [] synonym: "inhibition of steroid metabolic process" NARROW [] synonym: "negative regulation of steroid metabolism" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008202 ! negatively regulates steroid metabolic process relationship: RO:0002212 GO:0008202 ! negatively regulates steroid metabolic process [Term] id: GO:0045940 name: positive regulation of steroid metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "activation of steroid metabolic process" NARROW [] synonym: "positive regulation of steroid metabolism" EXACT [] synonym: "stimulation of steroid metabolic process" NARROW [] synonym: "up regulation of steroid metabolic process" EXACT [] synonym: "up-regulation of steroid metabolic process" EXACT [] synonym: "upregulation of steroid metabolic process" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008202 ! positively regulates steroid metabolic process relationship: RO:0002213 GO:0008202 ! positively regulates steroid metabolic process [Term] id: GO:0045947 name: negative regulation of translational initiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "down regulation of translational initiation" EXACT [] synonym: "down-regulation of translational initiation" EXACT [] synonym: "downregulation of translational initiation" EXACT [] synonym: "inhibition of translational initiation" NARROW [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006413 ! negatively regulates translational initiation relationship: RO:0002212 GO:0006413 ! negatively regulates translational initiation [Term] id: GO:0045948 name: positive regulation of translational initiation def: "Any process that activates or increases the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "activation of translational initiation" NARROW [] synonym: "stimulation of translational initiation" NARROW [] synonym: "up regulation of translational initiation" EXACT [] synonym: "up-regulation of translational initiation" EXACT [] synonym: "upregulation of translational initiation" EXACT [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006413 ! positively regulates translational initiation relationship: RO:0002213 GO:0006413 ! positively regulates translational initiation [Term] id: GO:0045986 name: negative regulation of smooth muscle contraction def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "down regulation of smooth muscle contraction" EXACT [] synonym: "down-regulation of smooth muscle contraction" EXACT [] synonym: "downregulation of smooth muscle contraction" EXACT [] synonym: "inhibition of smooth muscle contraction" NARROW [] synonym: "smooth muscle relaxation" RELATED [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006939 ! negatively regulates smooth muscle contraction relationship: RO:0002212 GO:0006939 ! negatively regulates smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045987 name: positive regulation of smooth muscle contraction def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "activation of smooth muscle contraction" NARROW [] synonym: "stimulation of smooth muscle contraction" NARROW [] synonym: "up regulation of smooth muscle contraction" EXACT [] synonym: "up-regulation of smooth muscle contraction" EXACT [] synonym: "upregulation of smooth muscle contraction" EXACT [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006939 ! positively regulates smooth muscle contraction relationship: RO:0002213 GO:0006939 ! positively regulates smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045988 name: negative regulation of striated muscle contraction def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "down regulation of striated muscle contraction" EXACT [] synonym: "down-regulation of striated muscle contraction" EXACT [] synonym: "downregulation of striated muscle contraction" EXACT [] synonym: "inhibition of striated muscle contraction" NARROW [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006941 ! negatively regulates striated muscle contraction relationship: RO:0002212 GO:0006941 ! negatively regulates striated muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045989 name: positive regulation of striated muscle contraction def: "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "activation of striated muscle contraction" NARROW [] synonym: "stimulation of striated muscle contraction" NARROW [] synonym: "up regulation of striated muscle contraction" EXACT [] synonym: "up-regulation of striated muscle contraction" EXACT [] synonym: "upregulation of striated muscle contraction" EXACT [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006941 ! positively regulates striated muscle contraction relationship: RO:0002213 GO:0006941 ! positively regulates striated muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045992 name: negative regulation of embryonic development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "down regulation of embryonic development" EXACT [] synonym: "down-regulation of embryonic development" EXACT [] synonym: "downregulation of embryonic development" EXACT [] synonym: "inhibition of embryonic development" NARROW [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009790 ! negatively regulates embryo development relationship: RO:0002212 GO:0009790 ! negatively regulates embryo development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0045995 name: regulation of embryonic development def: "Any process that modulates the frequency, rate or extent of embryonic development." [GOC:go_curators] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009790 ! regulates embryo development relationship: RO:0002211 GO:0009790 ! regulates embryo development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046013 name: regulation of T cell homeostatic proliferation def: "Any process that modulates the frequency, rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "regulation of resting T cell proliferation" EXACT [] synonym: "regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "regulation of T-cell homeostatic proliferation" EXACT [] synonym: "regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001777 ! regulates T cell homeostatic proliferation relationship: RO:0002211 GO:0001777 ! regulates T cell homeostatic proliferation [Term] id: GO:0046014 name: negative regulation of T cell homeostatic proliferation def: "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "down regulation of T cell homeostatic proliferation" EXACT [] synonym: "down-regulation of T cell homeostatic proliferation" EXACT [] synonym: "downregulation of T cell homeostatic proliferation" EXACT [] synonym: "inhibition of T cell homeostatic proliferation" NARROW [] synonym: "negative regulation of resting T cell proliferation" EXACT [] synonym: "negative regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "negative regulation of T-cell homeostatic proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042130 ! negative regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001777 ! negatively regulates T cell homeostatic proliferation relationship: RO:0002212 GO:0001777 ! negatively regulates T cell homeostatic proliferation [Term] id: GO:0046112 name: nucleobase biosynthetic process def: "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase anabolism" EXACT [] synonym: "nucleobase biosynthesis" EXACT [] synonym: "nucleobase formation" EXACT [] synonym: "nucleobase synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0009112 ! nucleobase metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:18282 ! has primary output nucleobase relationship: RO:0004008 CHEBI:18282 ! has primary output nucleobase [Term] id: GO:0046113 name: nucleobase catabolic process def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase breakdown" EXACT [] synonym: "nucleobase catabolism" EXACT [] synonym: "nucleobase degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0009112 ! nucleobase metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:18282 ! has primary input nucleobase relationship: RO:0004009 CHEBI:18282 ! has primary input nucleobase [Term] id: GO:0046189 name: phenol-containing compound biosynthetic process def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [GOC:ai] synonym: "phenol-containing compound anabolism" EXACT [] synonym: "phenol-containing compound biosynthesis" EXACT [] synonym: "phenol-containing compound formation" EXACT [] synonym: "phenol-containing compound synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0018958 ! phenol-containing compound metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33853 ! has primary output phenols relationship: RO:0004008 CHEBI:33853 ! has primary output phenols [Term] id: GO:0046219 name: indolalkylamine biosynthetic process def: "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] synonym: "indolalkylamine anabolism" EXACT [] synonym: "indolalkylamine biosynthesis" EXACT [] synonym: "indolalkylamine formation" EXACT [] synonym: "indolalkylamine synthesis" EXACT [] xref: Reactome:R-HSA-209931 "Serotonin and melatonin biosynthesis" is_a: GO:0042401 ! biogenic amine biosynthetic process is_a: GO:0042435 ! indole-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:38631 ! has primary output aminoalkylindole relationship: RO:0004008 CHEBI:38631 ! has primary output aminoalkylindole [Term] id: GO:0046364 name: monosaccharide biosynthetic process def: "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide anabolism" EXACT [] synonym: "monosaccharide biosynthesis" EXACT [] synonym: "monosaccharide formation" EXACT [] synonym: "monosaccharide synthesis" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016051 ! carbohydrate biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35381 ! has primary output monosaccharide relationship: RO:0004008 CHEBI:35381 ! has primary output monosaccharide [Term] id: GO:0046365 name: monosaccharide catabolic process def: "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide breakdown" EXACT [] synonym: "monosaccharide catabolism" EXACT [] synonym: "monosaccharide degradation" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016052 ! carbohydrate catabolic process is_a: GO:0044282 ! small molecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide relationship: RO:0004009 CHEBI:35381 ! has primary input monosaccharide [Term] id: GO:0046394 name: carboxylic acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid anabolism" EXACT [] synonym: "carboxylic acid biosynthesis" EXACT [] synonym: "carboxylic acid formation" EXACT [] synonym: "carboxylic acid synthesis" EXACT [] is_a: GO:0016053 ! organic acid biosynthetic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:29067 ! has primary output carboxylic acid anion relationship: RO:0004008 CHEBI:29067 ! has primary output carboxylic acid anion [Term] id: GO:0046395 name: carboxylic acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid breakdown" EXACT [] synonym: "carboxylic acid catabolism" EXACT [] synonym: "carboxylic acid degradation" EXACT [] is_a: GO:0016054 ! organic acid catabolic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion relationship: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion [Term] id: GO:0046466 name: membrane lipid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] synonym: "membrane lipid breakdown" EXACT [] synonym: "membrane lipid catabolism" EXACT [] synonym: "membrane lipid degradation" EXACT [] synonym: "membrane lipid peroxidation" BROAD [GOC:tb] is_a: GO:0006643 ! membrane lipid metabolic process is_a: GO:0016042 ! lipid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0016020 ! occurs in membrane intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] id: GO:0046467 name: membrane lipid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] synonym: "membrane lipid anabolism" EXACT [] synonym: "membrane lipid biosynthesis" EXACT [] synonym: "membrane lipid formation" EXACT [] synonym: "membrane lipid synthesis" EXACT [] is_a: GO:0006643 ! membrane lipid metabolic process is_a: GO:0008610 ! lipid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: BFO:0000066 GO:0016020 ! occurs in membrane intersection_of: RO:0004008 CHEBI:18059 ! has primary output lipid [Term] id: GO:0046530 name: photoreceptor cell differentiation alt_id: GO:0007467 def: "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." [GOC:ai, ISBN:0198506732] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000210 ! results in acquisition of features of photoreceptor cell relationship: RO:0002315 CL:0000210 ! results in acquisition of features of photoreceptor cell [Term] id: GO:0046532 name: regulation of photoreceptor cell differentiation alt_id: GO:0045673 def: "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046530 ! regulates photoreceptor cell differentiation relationship: RO:0002211 GO:0046530 ! regulates photoreceptor cell differentiation [Term] id: GO:0046533 name: negative regulation of photoreceptor cell differentiation alt_id: GO:0045674 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "down regulation of photoreceptor cell differentiation" EXACT [] synonym: "down regulation of photoreceptor differentiation" EXACT [] synonym: "down-regulation of photoreceptor cell differentiation" EXACT [] synonym: "down-regulation of photoreceptor differentiation" EXACT [] synonym: "downregulation of photoreceptor cell differentiation" EXACT [] synonym: "downregulation of photoreceptor differentiation" EXACT [] synonym: "inhibition of photoreceptor cell differentiation" NARROW [] synonym: "inhibition of photoreceptor differentiation" NARROW [] synonym: "negative regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046530 ! negatively regulates photoreceptor cell differentiation relationship: RO:0002212 GO:0046530 ! negatively regulates photoreceptor cell differentiation [Term] id: GO:0046534 name: positive regulation of photoreceptor cell differentiation alt_id: GO:0045675 def: "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "activation of photoreceptor cell differentiation" NARROW [] synonym: "activation of photoreceptor differentiation" NARROW [] synonym: "positive regulation of photoreceptor differentiation" EXACT [] synonym: "stimulation of photoreceptor cell differentiation" NARROW [] synonym: "stimulation of photoreceptor differentiation" NARROW [] synonym: "up regulation of photoreceptor cell differentiation" EXACT [] synonym: "up regulation of photoreceptor differentiation" EXACT [] synonym: "up-regulation of photoreceptor cell differentiation" EXACT [] synonym: "up-regulation of photoreceptor differentiation" EXACT [] synonym: "upregulation of photoreceptor cell differentiation" EXACT [] synonym: "upregulation of photoreceptor differentiation" EXACT [] is_a: GO:0045666 ! positive regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046530 ! positively regulates photoreceptor cell differentiation relationship: RO:0002213 GO:0046530 ! positively regulates photoreceptor cell differentiation [Term] id: GO:0046545 name: development of primary female sexual characteristics def: "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: part_of GO:0046660 ! female sex differentiation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046546 name: development of primary male sexual characteristics def: "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: part_of GO:0046661 ! male sex differentiation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046548 name: retinal rod cell development def: "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000604 ! results in development of retinal rod cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060221 ! retinal rod cell differentiation relationship: RO:0002296 CL:0000604 ! results in development of retinal rod cell [Term] id: GO:0046549 name: retinal cone cell development def: "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000573 ! results in development of retinal cone cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0042670 ! retinal cone cell differentiation relationship: RO:0002296 CL:0000573 ! results in development of retinal cone cell [Term] id: GO:0046620 name: regulation of organ growth def: "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035265 ! regulates organ growth relationship: RO:0002211 GO:0035265 ! regulates organ growth property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046621 name: negative regulation of organ growth def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035265 ! negatively regulates organ growth relationship: RO:0002212 GO:0035265 ! negatively regulates organ growth property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046622 name: positive regulation of organ growth def: "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035265 ! positively regulates organ growth relationship: RO:0002213 GO:0035265 ! positively regulates organ growth property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046649 name: lymphocyte activation def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000542 ! has primary input lymphocyte relationship: RO:0004009 CL:0000542 ! has primary input lymphocyte [Term] id: GO:0046651 name: lymphocyte proliferation def: "The expansion of a lymphocyte population by cell division." [GOC:ai] is_a: GO:0032943 ! mononuclear cell proliferation is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000542 ! acts on population of lymphocyte relationship: RO:0012003 CL:0000542 ! acts on population of lymphocyte [Term] id: GO:0046660 name: female sex differentiation namespace: biological_process def: "The establishment of the sex of a female organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0007275 ! multicellular organism development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046661 name: male sex differentiation def: "The establishment of the sex of a male organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0007275 ! multicellular organism development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0046666 name: retinal cell programmed cell death def: "Programmed cell death that occurs in the developing retina." [GOC:bf] synonym: "programmed cell death, retina cells" EXACT [] synonym: "programmed cell death, retinal cells" EXACT [] synonym: "retina cell programmed cell death" EXACT [] synonym: "retina programmed cell death" EXACT [] synonym: "retinal programmed cell death" EXACT [] is_a: GO:0010623 ! programmed cell death involved in cell development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048592 ! eye morphogenesis [Term] id: GO:0046667 name: compound eye retinal cell programmed cell death def: "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." [PMID:12006672] is_a: GO:0046666 ! retinal cell programmed cell death intersection_of: GO:0046666 ! retinal cell programmed cell death intersection_of: RO:0002299 UBERON:0000018 ! results in maturation of compound eye relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0001745 ! compound eye morphogenesis relationship: RO:0002299 UBERON:0000018 ! results in maturation of compound eye [Term] id: GO:0046668 name: regulation of retinal cell programmed cell death def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046666 ! regulates retinal cell programmed cell death relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0046666 ! regulates retinal cell programmed cell death [Term] id: GO:0046669 name: regulation of compound eye retinal cell programmed cell death def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "regulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046668 ! regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046667 ! regulates compound eye retinal cell programmed cell death relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: RO:0002211 GO:0046667 ! regulates compound eye retinal cell programmed cell death [Term] id: GO:0046670 name: positive regulation of retinal cell programmed cell death def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "activation of retinal programmed cell death" NARROW [] synonym: "positive regulation of retinal programmed cell death" EXACT [GOC:tb] synonym: "stimulation of retinal programmed cell death" NARROW [] synonym: "up regulation of retinal programmed cell death" EXACT [] synonym: "up-regulation of retinal programmed cell death" EXACT [] synonym: "upregulation of retinal programmed cell death" EXACT [] is_a: GO:0043068 ! positive regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046666 ! positively regulates retinal cell programmed cell death relationship: RO:0002213 GO:0046666 ! positively regulates retinal cell programmed cell death [Term] id: GO:0046671 name: negative regulation of retinal cell programmed cell death def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "down regulation of retinal programmed cell death" EXACT [] synonym: "down-regulation of retinal programmed cell death" EXACT [] synonym: "downregulation of retinal programmed cell death" EXACT [] synonym: "inhibition of retinal programmed cell death" NARROW [] synonym: "negative regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043069 ! negative regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046666 ! negatively regulates retinal cell programmed cell death relationship: RO:0002212 GO:0046666 ! negatively regulates retinal cell programmed cell death [Term] id: GO:0046672 name: positive regulation of compound eye retinal cell programmed cell death def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "activation of retinal cell programmed cell death" BROAD [] synonym: "positive regulation of retinal cell programmed cell death" BROAD [] synonym: "stimulation of retinal cell programmed cell death" BROAD [] synonym: "up regulation of retinal cell programmed cell death" BROAD [] synonym: "up-regulation of retinal cell programmed cell death" BROAD [] synonym: "upregulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046670 ! positive regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046667 ! positively regulates compound eye retinal cell programmed cell death relationship: RO:0002213 GO:0046667 ! positively regulates compound eye retinal cell programmed cell death [Term] id: GO:0046673 name: negative regulation of compound eye retinal cell programmed cell death def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "down regulation of retinal cell programmed cell death" BROAD [] synonym: "down-regulation of retinal cell programmed cell death" BROAD [] synonym: "downregulation of retinal cell programmed cell death" BROAD [] synonym: "inhibition of retinal cell programmed cell death" BROAD [] synonym: "negative regulation of retina cell programmed cell death" BROAD [] synonym: "negative regulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046671 ! negative regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046667 ! negatively regulates compound eye retinal cell programmed cell death relationship: RO:0002212 GO:0046667 ! negatively regulates compound eye retinal cell programmed cell death [Term] id: GO:0046676 name: negative regulation of insulin secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin." [GOC:ai] synonym: "down regulation of insulin secretion" EXACT [] synonym: "down-regulation of insulin secretion" EXACT [] synonym: "downregulation of insulin secretion" EXACT [] synonym: "inhibition of insulin secretion" NARROW [] xref: Reactome:R-HSA-400042 "Adrenaline,noradrenaline inhibits insulin secretion" is_a: GO:0050709 ! negative regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030073 ! negatively regulates insulin secretion relationship: RO:0002212 GO:0030073 ! negatively regulates insulin secretion [Term] id: GO:0046681 name: response to carbamate def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." [ISBN:0721662544] synonym: "carbamate resistance" RELATED [] synonym: "carbamate susceptibility/resistance" RELATED [] is_a: GO:0017085 ! response to insecticide is_a: GO:1901698 ! response to nitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:13941 ! has primary input carbamate relationship: RO:0004009 CHEBI:13941 ! has primary input carbamate [Term] id: GO:0046692 name: sperm competition def: "Any process that contributes to the success of sperm fertilization in multiply-mated females." [PMID:10885514] xref: Wikipedia:Sperm_competition is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007320 ! insemination [Term] id: GO:0046697 name: decidualization def: "The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta." [ISBN:0721662544, PMID:11133685] synonym: "decidual cell reaction" EXACT [] xref: Wikipedia:Decidualization is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009888 ! tissue development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001893 ! maternal placenta development [Term] id: GO:0046716 name: muscle cell cellular homeostasis def: "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." [GOC:mah, PMID:3091429, PMID:7781901] synonym: "muscle fiber maintenance" NARROW [GOC:dph, GOC:tb] synonym: "muscle homeostasis" RELATED [GOC:dph] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: BFO:0000066 CL:0000187 ! occurs in muscle cell relationship: BFO:0000066 CL:0000187 ! occurs in muscle cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0046717 name: acid secretion def: "The controlled release of acid by a cell or a tissue." [GOC:ai] is_a: GO:0046903 ! secretion [Term] id: GO:0046785 name: microtubule polymerization def: "The addition of tubulin heterodimers to one or both ends of a microtubule." [GOC:ai, GOC:go_curators] synonym: "microtubule assembly" EXACT [] synonym: "microtubule formation" RELATED [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051258 ! protein polymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005874 ! results in assembly of microtubule relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002588 GO:0005874 ! results in assembly of microtubule relationship: starts_with GO:0007020 ! microtubule nucleation [Term] id: GO:0046822 name: regulation of nucleocytoplasmic transport def: "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." [GOC:bf] is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006913 ! regulates nucleocytoplasmic transport relationship: RO:0002211 GO:0006913 ! regulates nucleocytoplasmic transport [Term] id: GO:0046823 name: negative regulation of nucleocytoplasmic transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus." [GOC:bf] synonym: "down regulation of nucleocytoplasmic transport" EXACT [] synonym: "down-regulation of nucleocytoplasmic transport" EXACT [] synonym: "downregulation of nucleocytoplasmic transport" EXACT [] synonym: "inhibition of nucleocytoplasmic transport" NARROW [] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:0046822 ! regulation of nucleocytoplasmic transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006913 ! negatively regulates nucleocytoplasmic transport relationship: RO:0002212 GO:0006913 ! negatively regulates nucleocytoplasmic transport [Term] id: GO:0046824 name: positive regulation of nucleocytoplasmic transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." [GOC:bf] synonym: "activation of nucleocytoplasmic transport" NARROW [] synonym: "stimulation of nucleocytoplasmic transport" NARROW [] synonym: "up regulation of nucleocytoplasmic transport" EXACT [] synonym: "up-regulation of nucleocytoplasmic transport" EXACT [] synonym: "upregulation of nucleocytoplasmic transport" EXACT [] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:0046822 ! regulation of nucleocytoplasmic transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006913 ! positively regulates nucleocytoplasmic transport relationship: RO:0002213 GO:0006913 ! positively regulates nucleocytoplasmic transport [Term] id: GO:0046825 name: regulation of protein export from nucleus def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm." [GOC:bf] synonym: "regulation of protein export from cell nucleus" EXACT [] synonym: "regulation of protein export out of nucleus" EXACT [] synonym: "regulation of protein transport from nucleus to cytoplasm" EXACT [] synonym: "regulation of protein-nucleus export" EXACT [] is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0046822 ! regulation of nucleocytoplasmic transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006611 ! regulates protein export from nucleus relationship: RO:0002211 GO:0006611 ! regulates protein export from nucleus [Term] id: GO:0046826 name: negative regulation of protein export from nucleus def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm." [GOC:bf] synonym: "down regulation of protein export from nucleus" EXACT [] synonym: "down-regulation of protein export from nucleus" EXACT [] synonym: "downregulation of protein export from nucleus" EXACT [] synonym: "inhibition of protein export from nucleus" NARROW [] synonym: "negative regulation of protein export from cell nucleus" EXACT [] synonym: "negative regulation of protein export out of nucleus" EXACT [] synonym: "negative regulation of protein transport from nucleus to cytoplasm" EXACT [] synonym: "negative regulation of protein-nucleus export" EXACT [] is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport is_a: GO:0046825 ! regulation of protein export from nucleus is_a: GO:0051457 ! maintenance of protein location in nucleus is_a: GO:0090317 ! negative regulation of intracellular protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006611 ! negatively regulates protein export from nucleus relationship: RO:0002212 GO:0006611 ! negatively regulates protein export from nucleus [Term] id: GO:0046827 name: positive regulation of protein export from nucleus def: "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm." [GOC:bf] synonym: "activation of protein export from nucleus" NARROW [] synonym: "positive regulation of protein export from cell nucleus" EXACT [] synonym: "positive regulation of protein export out of nucleus" EXACT [] synonym: "positive regulation of protein transport from nucleus to cytoplasm" EXACT [] synonym: "positive regulation of protein-nucleus export" EXACT [] synonym: "stimulation of protein export from nucleus" NARROW [] synonym: "up regulation of protein export from nucleus" EXACT [] synonym: "up-regulation of protein export from nucleus" EXACT [] synonym: "upregulation of protein export from nucleus" EXACT [] is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport is_a: GO:0046825 ! regulation of protein export from nucleus is_a: GO:0090316 ! positive regulation of intracellular protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006611 ! positively regulates protein export from nucleus relationship: RO:0002213 GO:0006611 ! positively regulates protein export from nucleus [Term] id: GO:0046828 name: regulation of RNA import into nucleus def: "Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus." [GOC:bf] synonym: "regulation of RNA import into cell nucleus" EXACT [] synonym: "regulation of RNA transport from cytoplasm to nucleus" EXACT [] synonym: "regulation of RNA-nucleus import" EXACT [] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0046822 ! regulation of nucleocytoplasmic transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006404 ! regulates RNA import into nucleus relationship: RO:0002211 GO:0006404 ! regulates RNA import into nucleus [Term] id: GO:0046829 name: negative regulation of RNA import into nucleus def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus." [GOC:bf] synonym: "down regulation of RNA import into nucleus" EXACT [] synonym: "down-regulation of RNA import into nucleus" EXACT [] synonym: "downregulation of RNA import into nucleus" EXACT [] synonym: "inhibition of RNA import into nucleus" NARROW [] synonym: "negative regulation of RNA import into cell nucleus" EXACT [] synonym: "negative regulation of RNA transport from cytoplasm to nucleus" EXACT [] synonym: "negative regulation of RNA-nucleus import" EXACT [] is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport is_a: GO:0046828 ! regulation of RNA import into nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006404 ! negatively regulates RNA import into nucleus relationship: RO:0002212 GO:0006404 ! negatively regulates RNA import into nucleus [Term] id: GO:0046830 name: positive regulation of RNA import into nucleus def: "Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus." [GOC:bf] synonym: "activation of RNA import into nucleus" NARROW [] synonym: "positive regulation of RNA import into cell nucleus" EXACT [] synonym: "positive regulation of RNA transport from cytoplasm to nucleus" EXACT [] synonym: "positive regulation of RNA-nucleus import" EXACT [] synonym: "stimulation of RNA import into nucleus" NARROW [] synonym: "up regulation of RNA import into nucleus" EXACT [] synonym: "up-regulation of RNA import into nucleus" EXACT [] synonym: "upregulation of RNA import into nucleus" EXACT [] is_a: GO:0032241 ! positive regulation of nucleobase-containing compound transport is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport is_a: GO:0046828 ! regulation of RNA import into nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006404 ! positively regulates RNA import into nucleus relationship: RO:0002213 GO:0006404 ! positively regulates RNA import into nucleus [Term] id: GO:0046831 name: regulation of RNA export from nucleus def: "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm." [GOC:bf] synonym: "regulation of RNA export from cell nucleus" EXACT [] synonym: "regulation of RNA export out of nucleus" EXACT [] synonym: "regulation of RNA transport from nucleus to cytoplasm" EXACT [] synonym: "regulation of RNA-nucleus export" EXACT [] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0046822 ! regulation of nucleocytoplasmic transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006405 ! regulates RNA export from nucleus relationship: RO:0002211 GO:0006405 ! regulates RNA export from nucleus [Term] id: GO:0046832 name: negative regulation of RNA export from nucleus def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm." [GOC:bf] synonym: "down regulation of RNA export from nucleus" EXACT [] synonym: "down-regulation of RNA export from nucleus" EXACT [] synonym: "downregulation of RNA export from nucleus" EXACT [] synonym: "inhibition of RNA export from nucleus" NARROW [] synonym: "negative regulation of RNA export from cell nucleus" EXACT [] synonym: "negative regulation of RNA export out of nucleus" EXACT [] synonym: "negative regulation of RNA transport from nucleus to cytoplasm" EXACT [] synonym: "negative regulation of RNA-nucleus export" EXACT [] is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport is_a: GO:0046831 ! regulation of RNA export from nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006405 ! negatively regulates RNA export from nucleus relationship: RO:0002212 GO:0006405 ! negatively regulates RNA export from nucleus [Term] id: GO:0046833 name: positive regulation of RNA export from nucleus def: "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm." [GOC:bf] synonym: "activation of RNA export from nucleus" NARROW [] synonym: "positive regulation of RNA export from cell nucleus" EXACT [] synonym: "positive regulation of RNA export out of nucleus" EXACT [] synonym: "positive regulation of RNA transport from nucleus to cytoplasm" EXACT [] synonym: "positive regulation of RNA-nucleus export" EXACT [] synonym: "stimulation of RNA export from nucleus" NARROW [] synonym: "up regulation of RNA export from nucleus" EXACT [] synonym: "up-regulation of RNA export from nucleus" EXACT [] synonym: "upregulation of RNA export from nucleus" EXACT [] is_a: GO:0032241 ! positive regulation of nucleobase-containing compound transport is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport is_a: GO:0046831 ! regulation of RNA export from nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006405 ! positively regulates RNA export from nucleus relationship: RO:0002213 GO:0006405 ! positively regulates RNA export from nucleus [Term] id: GO:0046873 name: metal ion transmembrane transporter activity def: "Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai] synonym: "heavy metal ion porter activity" NARROW [] synonym: "heavy metal ion transporter activity" NARROW [] synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] synonym: "heavy metal-exporting ATPase activity" NARROW [] synonym: "high affinity metal ion uptake transporter activity" NARROW [] synonym: "low affinity metal ion uptake transporter activity" NARROW [] is_a: GO:0008324 ! monoatomic cation transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: part_of GO:0030001 ! metal ion transport relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation [Term] id: GO:0046879 name: hormone secretion def: "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [ISBN:0198506732] is_a: GO:0009914 ! hormone transport is_a: GO:0023061 ! signal release [Term] id: GO:0046883 name: regulation of hormone secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0010817 ! regulation of hormone levels is_a: GO:0023051 ! regulation of signaling is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046879 ! regulates hormone secretion relationship: RO:0002211 GO:0046879 ! regulates hormone secretion [Term] id: GO:0046887 name: positive regulation of hormone secretion def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "activation of hormone secretion" NARROW [] synonym: "stimulation of hormone secretion" NARROW [] synonym: "up regulation of hormone secretion" EXACT [] synonym: "up-regulation of hormone secretion" EXACT [] synonym: "upregulation of hormone secretion" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046879 ! positively regulates hormone secretion relationship: RO:0002213 GO:0046879 ! positively regulates hormone secretion [Term] id: GO:0046888 name: negative regulation of hormone secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "down regulation of hormone secretion" EXACT [] synonym: "down-regulation of hormone secretion" EXACT [] synonym: "downregulation of hormone secretion" EXACT [] synonym: "inhibition of hormone secretion" NARROW [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046879 ! negatively regulates hormone secretion relationship: RO:0002212 GO:0046879 ! negatively regulates hormone secretion [Term] id: GO:0046889 name: positive regulation of lipid biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "activation of lipid biosynthetic process" NARROW [] synonym: "positive regulation of lipid anabolism" EXACT [] synonym: "positive regulation of lipid biosynthesis" EXACT [] synonym: "positive regulation of lipid formation" EXACT [] synonym: "positive regulation of lipid synthesis" EXACT [] synonym: "positive regulation of lipogenesis" EXACT [GOC:sl] synonym: "stimulation of lipid biosynthetic process" NARROW [] synonym: "up regulation of lipid biosynthetic process" EXACT [] synonym: "up-regulation of lipid biosynthetic process" EXACT [] synonym: "upregulation of lipid biosynthetic process" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008610 ! positively regulates lipid biosynthetic process relationship: RO:0002213 GO:0008610 ! positively regulates lipid biosynthetic process [Term] id: GO:0046890 name: regulation of lipid biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "regulation of lipid anabolism" EXACT [] synonym: "regulation of lipid biosynthesis" EXACT [] synonym: "regulation of lipid formation" EXACT [] synonym: "regulation of lipid synthesis" EXACT [] synonym: "regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008610 ! regulates lipid biosynthetic process relationship: RO:0002211 GO:0008610 ! regulates lipid biosynthetic process [Term] id: GO:0046903 name: secretion namespace: biological_process def: "The controlled release of a substance by a cell or a tissue." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport [Term] id: GO:0046907 name: intracellular transport alt_id: GO:1902582 def: "The directed movement of substances within a cell." [GOC:ai] subset: gocheck_do_not_annotate synonym: "single organism intracellular transport" RELATED [GOC:TermGenie] synonym: "single-organism intracellular transport" RELATED [] is_a: GO:0006810 ! transport is_a: GO:0051641 ! cellular localization is_a: GO:0051649 ! establishment of localization in cell intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure relationship: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure created_by: jl creation_date: 2013-12-18T14:04:50Z [Term] id: GO:0046928 name: regulation of neurotransmitter secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." [GOC:ai] is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0051588 ! regulation of neurotransmitter transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007269 ! regulates neurotransmitter secretion relationship: RO:0002211 GO:0007269 ! regulates neurotransmitter secretion [Term] id: GO:0046929 name: negative regulation of neurotransmitter secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:ai] synonym: "conotoxin activity" NARROW [] synonym: "down regulation of neurotransmitter secretion" EXACT [] synonym: "down-regulation of neurotransmitter secretion" EXACT [] synonym: "downregulation of neurotransmitter secretion" EXACT [] synonym: "inhibition of neurotransmitter secretion" NARROW [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051589 ! negative regulation of neurotransmitter transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007269 ! negatively regulates neurotransmitter secretion relationship: RO:0002212 GO:0007269 ! negatively regulates neurotransmitter secretion [Term] id: GO:0046942 name: carboxylic acid transport def: "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] is_a: GO:0015711 ! organic anion transport is_a: GO:0015849 ! organic acid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion relationship: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion [Term] id: GO:0046943 name: carboxylic acid transmembrane transporter activity def: "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] xref: Reactome:R-HSA-390347 "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion relationship: part_of GO:1905039 ! carboxylic acid transmembrane transport relationship: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion [Term] id: GO:0047496 name: vesicle transport along microtubule def: "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:ecd, GOC:rl] synonym: "microtubule-based vesicle localization" EXACT [GOC:rl] is_a: GO:0072384 ! organelle transport along microtubule is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0006810 ! transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0048048 name: embryonic eye morphogenesis def: "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0048592 ! eye morphogenesis [Term] id: GO:0048066 name: developmental pigmentation def: "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." [ISBN:0582227089] synonym: "pigmentation during development" RELATED [] is_a: GO:0043473 ! pigmentation [Term] id: GO:0048070 name: regulation of developmental pigmentation def: "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "regulation of pigmentation during development" EXACT [GOC:dph, GOC:tb] is_a: GO:0120305 ! regulation of pigmentation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048066 ! regulates developmental pigmentation relationship: RO:0002211 GO:0048066 ! regulates developmental pigmentation [Term] id: GO:0048086 name: negative regulation of developmental pigmentation def: "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "down regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of pigmentation" NARROW [] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048066 ! negatively regulates developmental pigmentation relationship: RO:0002212 GO:0048066 ! negatively regulates developmental pigmentation [Term] id: GO:0048087 name: positive regulation of developmental pigmentation def: "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "activation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] synonym: "stimulation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] synonym: "up regulation of developmental pigmentation" EXACT [GOC:dph] synonym: "up-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048066 ! positively regulates developmental pigmentation relationship: RO:0002213 GO:0048066 ! positively regulates developmental pigmentation [Term] id: GO:0048103 name: somatic stem cell division def: "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." [GOC:jid, ISBN:0582227089] synonym: "somatic stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000723 ! has primary input somatic stem cell relationship: RO:0004009 CL:0000723 ! has primary input somatic stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048132 name: female germ-line stem cell asymmetric division alt_id: GO:0048141 def: "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." [GOC:jid, GOC:mtg_sensu] synonym: "female germ-line stem cell renewal" EXACT [] is_a: GO:0098728 ! germline stem cell asymmetric division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000022 ! has primary input female germ line stem cell relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048477 ! oogenesis relationship: RO:0004009 CL:0000022 ! has primary input female germ line stem cell [Term] id: GO:0048137 name: spermatocyte division def: "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids." [GOC:jid, GOC:pr, ISBN:0879694238] synonym: "spermatocyte cell division" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000017 ! has primary input spermatocyte relationship: part_of GO:0007283 ! spermatogenesis relationship: RO:0004009 CL:0000017 ! has primary input spermatocyte property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048144 name: fibroblast proliferation def: "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." [GOC:jid] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000057 ! acts on population of fibroblast relationship: RO:0012003 CL:0000057 ! acts on population of fibroblast property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048145 name: regulation of fibroblast proliferation def: "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048144 ! regulates fibroblast proliferation relationship: RO:0002211 GO:0048144 ! regulates fibroblast proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048146 name: positive regulation of fibroblast proliferation def: "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "activation of fibroblast proliferation" NARROW [] synonym: "stimulation of fibroblast proliferation" NARROW [] synonym: "up regulation of fibroblast proliferation" EXACT [] synonym: "up-regulation of fibroblast proliferation" EXACT [] synonym: "upregulation of fibroblast proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048144 ! positively regulates fibroblast proliferation relationship: RO:0002213 GO:0048144 ! positively regulates fibroblast proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048147 name: negative regulation of fibroblast proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "down regulation of fibroblast proliferation" EXACT [] synonym: "down-regulation of fibroblast proliferation" EXACT [] synonym: "downregulation of fibroblast proliferation" EXACT [] synonym: "inhibition of fibroblast proliferation" NARROW [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048144 ! negatively regulates fibroblast proliferation relationship: RO:0002212 GO:0048144 ! negatively regulates fibroblast proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048193 name: Golgi vesicle transport def: "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." [GOC:jid, ISBN:0716731363, PMID:10219233] subset: goslim_yeast synonym: "Golgi-derived vesicle transport" RELATED [] is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: RO:0002344 GO:0005798 ! results in transport to from or in Golgi-associated vesicle relationship: RO:0002344 GO:0005798 ! results in transport to from or in Golgi-associated vesicle [Term] id: GO:0048194 name: Golgi vesicle budding def: "The evagination of the Golgi membrane, resulting in formation of a vesicle." [GOC:jid, ISBN:0716731363, PMID:10219233] synonym: "dictyosome vesicle budding" NARROW [] synonym: "Golgi-derived vesicle budding" EXACT [] is_a: GO:0006900 ! vesicle budding from membrane intersection_of: GO:0006900 ! vesicle budding from membrane intersection_of: BFO:0000066 GO:0000139 ! occurs in Golgi membrane intersection_of: RO:0004008 GO:0005798 ! has primary output Golgi-associated vesicle relationship: BFO:0000066 GO:0000139 ! occurs in Golgi membrane relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: RO:0004008 GO:0005798 ! has primary output Golgi-associated vesicle [Term] id: GO:0048199 name: vesicle targeting, to, from or within Golgi def: "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "dictyosome vesicle targeting" NARROW [] synonym: "Golgi vesicle targeting" EXACT [] synonym: "vesicle targeting, to, from or within dictyosome" NARROW [] is_a: GO:0006903 ! vesicle targeting intersection_of: GO:0006903 ! vesicle targeting intersection_of: RO:0002344 GO:0005794 ! results in transport to from or in Golgi apparatus intersection_of: RO:0004009 GO:0005798 ! has primary input Golgi-associated vesicle relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: RO:0002344 GO:0005794 ! results in transport to from or in Golgi apparatus relationship: RO:0004009 GO:0005798 ! has primary input Golgi-associated vesicle [Term] id: GO:0048209 name: regulation of vesicle targeting, to, from or within Golgi def: "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "regulation of Golgi vesicle targeting" EXACT [] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048199 ! regulates vesicle targeting, to, from or within Golgi relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0048199 ! regulates vesicle targeting, to, from or within Golgi [Term] id: GO:0048232 name: male gamete generation def: "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." [GOC:dph, GOC:jid] is_a: GO:0007276 ! gamete generation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048240 name: sperm capacitation def: "A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium." [GOC:jid, ISBN:978-3-642-58301-8, PMID:11820818] comment: Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract. synonym: "sperm activation" RELATED [PMID:23180860] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0007286 ! spermatid development property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0048243 name: norepinephrine secretion def: "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." [GOC:ef, GOC:jid] synonym: "noradrenaline secretion" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0023061 ! signal release is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0048251 name: elastic fiber assembly def: "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." [GOC:jid, PMID:10841810, PMID:12615674] synonym: "elastic fibre assembly" EXACT [] synonym: "elastin fiber assembly" EXACT [GOC:BHF] synonym: "elastin fibre assembly" EXACT [GOC:BHF] is_a: GO:0085029 ! extracellular matrix assembly is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0071953 ! results in assembly of elastic fiber relationship: RO:0002588 GO:0071953 ! results in assembly of elastic fiber [Term] id: GO:0048280 name: vesicle fusion with Golgi apparatus def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." [GOC:jid] is_a: GO:0006906 ! vesicle fusion is_a: GO:0007030 ! Golgi organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005794 ! results in fusion of Golgi apparatus intersection_of: RO:0012008 GO:0031982 ! results in fusion of vesicle relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: RO:0012008 GO:0005794 ! results in fusion of Golgi apparatus relationship: RO:0012008 GO:0031982 ! results in fusion of vesicle [Term] id: GO:0048284 name: organelle fusion def: "The creation of a single organelle from two or more organelles." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0043226 ! results in fusion of organelle relationship: RO:0012008 GO:0043226 ! results in fusion of organelle [Term] id: GO:0048285 name: organelle fission def: "The creation of two or more organelles by division of one organelle." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fission_of GO:0043226 ! organelle relationship: results_in_fission_of GO:0043226 ! organelle [Term] id: GO:0048288 name: nuclear membrane fusion involved in karyogamy def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." [GOC:jid] synonym: "nuclear membrane fusion during karyogamy" RELATED [GOC:dph, GOC:tb] is_a: GO:0000740 ! nuclear membrane fusion intersection_of: GO:0000740 ! nuclear membrane fusion intersection_of: part_of GO:0000741 ! karyogamy relationship: part_of GO:0000741 ! karyogamy [Term] id: GO:0048308 name: organelle inheritance def: "The partitioning of organelles between daughter cells at cell division." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization [Term] id: GO:0048313 name: Golgi inheritance def: "The partitioning of Golgi apparatus between daughter cells at cell division." [GOC:jid, PMID:12851069] synonym: "Golgi apparatus inheritance" EXACT [] synonym: "Golgi division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi partitioning" EXACT [] xref: Reactome:R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" is_a: GO:0007030 ! Golgi organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: results_in_distribution_of GO:0005794 ! Golgi apparatus relationship: results_in_distribution_of GO:0005794 ! Golgi apparatus [Term] id: GO:0048318 name: axial mesoderm development def: "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003068 ! results in development of axial mesoderm relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002296 UBERON:0003068 ! results in development of axial mesoderm [Term] id: GO:0048319 name: axial mesoderm morphogenesis def: "The process in which the anatomical structures of the axial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003068 ! results in morphogenesis of axial mesoderm relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0048318 ! axial mesoderm development relationship: RO:0002298 UBERON:0003068 ! results in morphogenesis of axial mesoderm [Term] id: GO:0048320 name: axial mesoderm formation def: "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] xref: Reactome:R-HSA-9796292 "Formation of axial mesoderm" is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003068 ! results in formation of anatomical entity axial mesoderm relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0048319 ! axial mesoderm morphogenesis relationship: RO:0002297 UBERON:0003068 ! results in formation of anatomical entity axial mesoderm [Term] id: GO:0048332 name: mesoderm morphogenesis def: "The process in which the anatomical structures of the mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000926 ! results in morphogenesis of mesoderm relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007498 ! mesoderm development relationship: RO:0002298 UBERON:0000926 ! results in morphogenesis of mesoderm [Term] id: GO:0048333 name: mesodermal cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." [GOC:dgh] synonym: "mesoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000222 ! results in acquisition of features of mesodermal cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0001707 ! mesoderm formation relationship: RO:0002315 CL:0000222 ! results in acquisition of features of mesodermal cell [Term] id: GO:0048339 name: paraxial mesoderm development def: "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." [GOC:dgh] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003077 ! results in development of paraxial mesoderm relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0003077 ! results in development of paraxial mesoderm [Term] id: GO:0048340 name: paraxial mesoderm morphogenesis def: "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003077 ! results in morphogenesis of paraxial mesoderm relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0048339 ! paraxial mesoderm development relationship: RO:0002298 UBERON:0003077 ! results in morphogenesis of paraxial mesoderm [Term] id: GO:0048341 name: paraxial mesoderm formation def: "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] xref: Reactome:R-HSA-9793380 "Formation of paraxial mesoderm" is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003077 ! results in formation of anatomical entity paraxial mesoderm relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0048340 ! paraxial mesoderm morphogenesis relationship: RO:0002297 UBERON:0003077 ! results in formation of anatomical entity paraxial mesoderm [Term] id: GO:0048368 name: lateral mesoderm development def: "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." [GOC:go_curators] synonym: "lateral plate mesoderm development" EXACT [] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003081 ! results in development of lateral plate mesoderm relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0003081 ! results in development of lateral plate mesoderm [Term] id: GO:0048369 name: lateral mesoderm morphogenesis def: "The process in which the anatomical structures of the lateral mesoderm are generated and organized." [GOC:go_curators] synonym: "lateral plate mesoderm morphogenesis" EXACT [] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0048368 ! lateral mesoderm development relationship: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm [Term] id: GO:0048370 name: lateral mesoderm formation def: "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:jid] synonym: "lateral plate mesoderm biosynthesis" EXACT [] synonym: "lateral plate mesoderm formation" EXACT [] xref: Reactome:R-HSA-9758920 "Formation of lateral plate mesoderm" is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0048369 ! lateral mesoderm morphogenesis relationship: RO:0002298 UBERON:0003081 ! results in morphogenesis of lateral plate mesoderm [Term] id: GO:0048389 name: intermediate mesoderm development def: "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003064 ! results in development of intermediate mesoderm relationship: RO:0002296 UBERON:0003064 ! results in development of intermediate mesoderm [Term] id: GO:0048390 name: intermediate mesoderm morphogenesis def: "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003064 ! results in morphogenesis of intermediate mesoderm relationship: part_of GO:0048389 ! intermediate mesoderm development relationship: RO:0002298 UBERON:0003064 ! results in morphogenesis of intermediate mesoderm [Term] id: GO:0048391 name: intermediate mesoderm formation def: "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] xref: Reactome:R-HSA-9761174 "Formation of intermediate mesoderm" is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003064 ! results in formation of anatomical entity intermediate mesoderm relationship: part_of GO:0048390 ! intermediate mesoderm morphogenesis relationship: RO:0002297 UBERON:0003064 ! results in formation of anatomical entity intermediate mesoderm [Term] id: GO:0048468 name: cell development def: "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." [GOC:go_curators] subset: goslim_candida synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0008150 ! biological process intersection_of: RO:0002296 CL:0000000 ! results in development of cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0030154 ! cell differentiation relationship: RO:0002296 CL:0000000 ! results in development of cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048469 name: cell maturation def: "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." [GOC:go_curators] subset: goslim_pir synonym: "functional differentiation" RELATED [GOC:dph] is_a: GO:0048869 ! cellular developmental process is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000000 ! results in maturation of cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0048468 ! cell development relationship: RO:0002299 CL:0000000 ! results in maturation of cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048477 name: oogenesis alt_id: GO:0009993 alt_id: GO:0048157 def: "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] synonym: "ovum development" EXACT systematic_synonym [] xref: Wikipedia:Oogenesis is_a: GO:0007281 ! germ cell development is_a: GO:0007292 ! female gamete generation intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0000025 ! results in development of egg cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002296 CL:0000025 ! results in development of egg cell [Term] id: GO:0048483 name: autonomic nervous system development def: "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." [FMA:9905, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002410 ! results in development of autonomic nervous system relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002296 UBERON:0002410 ! results in development of autonomic nervous system [Term] id: GO:0048485 name: sympathetic nervous system development def: "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." [FMA:9906, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000013 ! results in development of sympathetic nervous system relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048483 ! autonomic nervous system development relationship: RO:0002296 UBERON:0000013 ! results in development of sympathetic nervous system [Term] id: GO:0048486 name: parasympathetic nervous system development def: "The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia." [FMA:9907, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000011 ! results in development of parasympathetic nervous system relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048483 ! autonomic nervous system development relationship: RO:0002296 UBERON:0000011 ! results in development of parasympathetic nervous system [Term] id: GO:0048505 name: regulation of timing of cell differentiation def: "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." [GOC:bf, GOC:dph, GOC:jid, GOC:tb] synonym: "timing of cell differentiation" RELATED [] is_a: GO:0040034 ! regulation of development, heterochronic is_a: GO:0045595 ! regulation of cell differentiation [Term] id: GO:0048511 name: rhythmic process def: "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." [GOC:jid] subset: goslim_pir synonym: "rhythm" RELATED [] is_a: GO:0008150 ! biological process relationship: in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0048513 name: animal organ development namespace: biological_process def: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid] synonym: "development of an organ" EXACT [] synonym: "organogenesis" EXACT [] xref: Wikipedia:Organogenesis is_a: GO:0048856 ! anatomical structure development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25943" xsd:anyURI [Term] id: GO:0048514 name: blood vessel morphogenesis def: "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:jid] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001981 ! results in morphogenesis of blood vessel relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001568 ! blood vessel development relationship: RO:0002298 UBERON:0001981 ! results in morphogenesis of blood vessel [Term] id: GO:0048515 name: spermatid differentiation def: "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:jid] synonym: "spermatid cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000018 ! results in acquisition of features of spermatid relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0007283 ! spermatogenesis relationship: RO:0002315 CL:0000018 ! results in acquisition of features of spermatid property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0048518 name: positive regulation of biological process alt_id: GO:0043119 def: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] subset: gocheck_do_not_annotate synonym: "activation of biological process" NARROW [] synonym: "positive regulation of physiological process" EXACT [] synonym: "stimulation of biological process" NARROW [] synonym: "up regulation of biological process" EXACT [] synonym: "up-regulation of biological process" EXACT [] synonym: "upregulation of biological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008150 ! positively regulates biological process relationship: RO:0002213 GO:0008150 ! positively regulates biological process [Term] id: GO:0048519 name: negative regulation of biological process alt_id: GO:0043118 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] subset: gocheck_do_not_annotate synonym: "down regulation of biological process" EXACT [] synonym: "down-regulation of biological process" EXACT [] synonym: "downregulation of biological process" EXACT [] synonym: "inhibition of biological process" NARROW [] synonym: "negative regulation of physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008150 ! negatively regulates biological process relationship: RO:0002212 GO:0008150 ! negatively regulates biological process [Term] id: GO:0048520 name: positive regulation of behavior def: "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "activation of behavior" NARROW [] synonym: "stimulation of behavior" NARROW [] synonym: "up regulation of behavior" EXACT [] synonym: "up-regulation of behavior" EXACT [] synonym: "upregulation of behavior" EXACT [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007610 ! positively regulates behavior relationship: RO:0002213 GO:0007610 ! positively regulates behavior [Term] id: GO:0048521 name: negative regulation of behavior def: "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "down regulation of behavior" EXACT [] synonym: "down-regulation of behavior" EXACT [] synonym: "downregulation of behavior" EXACT [] synonym: "inhibition of behavior" NARROW [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007610 ! negatively regulates behavior relationship: RO:0002212 GO:0007610 ! negatively regulates behavior [Term] id: GO:0048522 name: positive regulation of cellular process alt_id: GO:0051242 def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] subset: gocheck_do_not_annotate synonym: "activation of cellular process" NARROW [] synonym: "positive regulation of cellular physiological process" EXACT [] synonym: "stimulation of cellular process" NARROW [] synonym: "up regulation of cellular process" EXACT [] synonym: "up-regulation of cellular process" EXACT [] synonym: "upregulation of cellular process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009987 ! positively regulates cellular process relationship: RO:0002213 GO:0009987 ! positively regulates cellular process [Term] id: GO:0048523 name: negative regulation of cellular process alt_id: GO:0051243 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] subset: gocheck_do_not_annotate synonym: "down regulation of cellular process" EXACT [] synonym: "down-regulation of cellular process" EXACT [] synonym: "downregulation of cellular process" EXACT [] synonym: "inhibition of cellular process" NARROW [] synonym: "negative regulation of cellular physiological process" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009987 ! negatively regulates cellular process relationship: RO:0002212 GO:0009987 ! negatively regulates cellular process [Term] id: GO:0048534 name: hematopoietic or lymphoid organ development def: "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." [GOC:add, GOC:rl, ISBN:0781735149] synonym: "haematopoietic or lymphoid organ development" EXACT [] synonym: "haemopoietic or lymphoid organ development" EXACT [] synonym: "hemopoietic or lymphoid organ development" EXACT [] is_a: GO:0048513 ! animal organ development relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0002520 ! immune system development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048536 name: spleen development def: "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions." [GOC:add, ISBN:0781735149] is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002106 ! results in development of spleen relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002296 UBERON:0002106 ! results in development of spleen [Term] id: GO:0048539 name: bone marrow development def: "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." [GOC:add, ISBN:0781735149] is_a: GO:0009888 ! tissue development is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002371 ! results in development of bone marrow relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060348 ! bone development relationship: RO:0002296 UBERON:0002371 ! results in development of bone marrow [Term] id: GO:0048545 name: response to steroid hormone def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:go_curators] synonym: "response to steroid hormone stimulus" EXACT [GOC:dos] is_a: GO:0009725 ! response to hormone is_a: GO:0033993 ! response to lipid intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:26764 ! has primary input steroid hormone relationship: RO:0004009 CHEBI:26764 ! has primary input steroid hormone property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048546 name: digestive tract morphogenesis alt_id: GO:0048547 def: "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:dph, GOC:go_curators, PMID:12618131] synonym: "alimentary canal morphogenesis" EXACT [] synonym: "digestive tube morphogenesis" EXACT [] synonym: "gastrointestinal tract morphogenesis" EXACT [] synonym: "gut morphogenesis" BROAD [GOC:dph] synonym: "intestinal morphogenesis" NARROW [] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001555 ! results in morphogenesis of digestive tract relationship: part_of GO:0048565 ! digestive tract development relationship: RO:0002298 UBERON:0001555 ! results in morphogenesis of digestive tract [Term] id: GO:0048562 name: embryonic organ morphogenesis def: "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048598 ! embryonic morphogenesis relationship: part_of GO:0048568 ! embryonic organ development [Term] id: GO:0048565 name: digestive tract development def: "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:go_curators] synonym: "gut development" BROAD [GOC:dph] synonym: "intestinal development" NARROW [] synonym: "intestine development" NARROW [] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001555 ! results in development of digestive tract relationship: part_of GO:0055123 ! digestive system development relationship: RO:0002296 UBERON:0001555 ! results in development of digestive tract [Term] id: GO:0048568 name: embryonic organ development def: "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] synonym: "embryonic organogenesis" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: part_of GO:0009790 ! embryo development intersection_of: RO:0002296 UBERON:0000062 ! results in development of organ relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0009790 ! embryo development relationship: RO:0002296 UBERON:0000062 ! results in development of organ property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048570 name: notochord morphogenesis def: "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002328 ! results in morphogenesis of notochord relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0030903 ! notochord development relationship: RO:0002298 UBERON:0002328 ! results in morphogenesis of notochord [Term] id: GO:0048580 name: regulation of post-embryonic development def: "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009791 ! regulates post-embryonic development relationship: RO:0002211 GO:0009791 ! regulates post-embryonic development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048581 name: negative regulation of post-embryonic development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "down regulation of post-embryonic development" EXACT [] synonym: "down-regulation of post-embryonic development" EXACT [] synonym: "downregulation of post-embryonic development" EXACT [] synonym: "inhibition of post-embryonic development" NARROW [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009791 ! negatively regulates post-embryonic development relationship: RO:0002212 GO:0009791 ! negatively regulates post-embryonic development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048582 name: positive regulation of post-embryonic development def: "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "activation of post-embryonic development" NARROW [] synonym: "stimulation of post-embryonic development" NARROW [] synonym: "up regulation of post-embryonic development" EXACT [] synonym: "up-regulation of post-embryonic development" EXACT [] synonym: "upregulation of post-embryonic development" EXACT [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009791 ! positively regulates post-embryonic development relationship: RO:0002213 GO:0009791 ! positively regulates post-embryonic development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048583 name: regulation of response to stimulus def: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050896 ! regulates response to stimulus relationship: RO:0002211 GO:0050896 ! regulates response to stimulus [Term] id: GO:0048584 name: positive regulation of response to stimulus def: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "activation of response to stimulus" NARROW [] synonym: "stimulation of response to stimulus" NARROW [] synonym: "up regulation of response to stimulus" EXACT [] synonym: "up-regulation of response to stimulus" EXACT [] synonym: "upregulation of response to stimulus" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050896 ! positively regulates response to stimulus relationship: RO:0002213 GO:0050896 ! positively regulates response to stimulus [Term] id: GO:0048585 name: negative regulation of response to stimulus def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "down regulation of response to stimulus" EXACT [] synonym: "down-regulation of response to stimulus" EXACT [] synonym: "downregulation of response to stimulus" EXACT [] synonym: "inhibition of response to stimulus" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050896 ! negatively regulates response to stimulus relationship: RO:0002212 GO:0050896 ! negatively regulates response to stimulus [Term] id: GO:0048588 name: developmental cell growth def: "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." [GOC:go_curators, GOC:isa_complete] subset: gocheck_do_not_annotate synonym: "developmental growth of a unicellular organism" EXACT [] is_a: GO:0016049 ! cell growth is_a: GO:0048589 ! developmental growth relationship: part_of GO:0048468 ! cell development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048589 name: developmental growth def: "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:go_curators] is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: part_of GO:0032502 ! developmental process relationship: part_of GO:0032502 ! developmental process [Term] id: GO:0048592 name: eye morphogenesis alt_id: GO:0048748 def: "The process in which the anatomical structures of the eye are generated and organized." [GOC:jid, GOC:mtg_sensu] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000970 ! results in morphogenesis of eye relationship: part_of GO:0001654 ! eye development relationship: RO:0002298 UBERON:0000970 ! results in morphogenesis of eye [Term] id: GO:0048593 name: camera-type eye morphogenesis alt_id: GO:0048594 alt_id: GO:0048595 def: "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:jid, GOC:mtg_sensu] synonym: "camera-style eye morphogenesis" EXACT [GOC:dph] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000019 ! results in morphogenesis of camera-type eye relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0043010 ! camera-type eye development relationship: RO:0002298 UBERON:0000019 ! results in morphogenesis of camera-type eye [Term] id: GO:0048596 name: embryonic camera-type eye morphogenesis def: "The process in which the anatomical structures of the eye are generated and organized during embryonic development." [GOC:jid, GOC:mtg_sensu] synonym: "embryonic eye morphogenesis" BROAD [] is_a: GO:0048048 ! embryonic eye morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031076 ! embryonic camera-type eye development relationship: part_of GO:0048593 ! camera-type eye morphogenesis [Term] id: GO:0048598 name: embryonic morphogenesis alt_id: GO:0048828 def: "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." [GOC:jid, GOC:mtg_sensu] synonym: "embryonic anatomical structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0009790 ! embryo development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048599 name: oocyte development def: "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:go_curators] is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000023 ! results in development of oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0009994 ! oocyte differentiation relationship: RO:0002296 CL:0000023 ! results in development of oocyte [Term] id: GO:0048601 name: oocyte morphogenesis def: "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." [GOC:go_curators] synonym: "oocyte morphogenesis during differentiation" EXACT [] is_a: GO:0000902 ! cell morphogenesis is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 CL:0000023 ! results in morphogenesis of oocyte relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: RO:0002298 CL:0000023 ! results in morphogenesis of oocyte [Term] id: GO:0048608 name: reproductive structure development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0061458 ! reproductive system development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23445" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048609 name: multicellular organismal reproductive process def: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb] subset: gocheck_do_not_annotate subset: goslim_drosophila synonym: "organismal reproductive process" BROAD [] synonym: "reproductive process in a multicellular organism" EXACT [] xref: Reactome:R-HSA-1474165 "Reproduction" is_a: GO:0022414 ! reproductive process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27054" xsd:anyURI [Term] id: GO:0048627 name: myoblast development def: "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000056 ! results in development of myoblast relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0045445 ! myoblast differentiation relationship: RO:0002296 CL:0000056 ! results in development of myoblast [Term] id: GO:0048628 name: myoblast maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000056 ! results in maturation of myoblast relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048627 ! myoblast development relationship: RO:0002299 CL:0000056 ! results in maturation of myoblast [Term] id: GO:0048630 name: skeletal muscle tissue growth def: "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0001134 ! results in growth of skeletal muscle tissue relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: RO:0002343 UBERON:0001134 ! results in growth of skeletal muscle tissue [Term] id: GO:0048631 name: regulation of skeletal muscle tissue growth def: "Any process that modulates the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048630 ! regulates skeletal muscle tissue growth relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0048630 ! regulates skeletal muscle tissue growth [Term] id: GO:0048632 name: negative regulation of skeletal muscle tissue growth def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "down regulation of skeletal muscle growth" EXACT [] synonym: "down-regulation of skeletal muscle growth" EXACT [] synonym: "downregulation of skeletal muscle growth" EXACT [] synonym: "inhibition of skeletal muscle growth" NARROW [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048640 ! negative regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048630 ! negatively regulates skeletal muscle tissue growth relationship: RO:0002212 GO:0048630 ! negatively regulates skeletal muscle tissue growth [Term] id: GO:0048633 name: positive regulation of skeletal muscle tissue growth def: "Any process that activates, maintains or increases the rate of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "activation of skeletal muscle growth" NARROW [] synonym: "stimulation of skeletal muscle growth" NARROW [] synonym: "up regulation of skeletal muscle growth" EXACT [] synonym: "up-regulation of skeletal muscle growth" EXACT [] synonym: "upregulation of skeletal muscle growth" EXACT [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048630 ! positively regulates skeletal muscle tissue growth relationship: RO:0002213 GO:0048630 ! positively regulates skeletal muscle tissue growth [Term] id: GO:0048634 name: regulation of muscle organ development def: "Any process that modulates the frequency, rate or extent of muscle development." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007517 ! regulates muscle organ development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0007517 ! regulates muscle organ development [Term] id: GO:0048635 name: negative regulation of muscle organ development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." [GOC:go_curators] synonym: "down regulation of muscle development" EXACT [] synonym: "down-regulation of muscle development" EXACT [] synonym: "downregulation of muscle development" EXACT [] synonym: "inhibition of muscle development" NARROW [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007517 ! negatively regulates muscle organ development relationship: RO:0002212 GO:0007517 ! negatively regulates muscle organ development [Term] id: GO:0048636 name: positive regulation of muscle organ development def: "Any process that activates, maintains or increases the rate of muscle development." [GOC:go_curators] synonym: "activation of muscle development" NARROW [] synonym: "stimulation of muscle development" NARROW [] synonym: "up regulation of muscle development" EXACT [] synonym: "up-regulation of muscle development" EXACT [] synonym: "upregulation of muscle development" EXACT [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007517 ! positively regulates muscle organ development relationship: RO:0002213 GO:0007517 ! positively regulates muscle organ development [Term] id: GO:0048638 name: regulation of developmental growth def: "Any process that modulates the frequency, rate or extent of developmental growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048589 ! regulates developmental growth relationship: RO:0002211 GO:0048589 ! regulates developmental growth [Term] id: GO:0048639 name: positive regulation of developmental growth def: "Any process that activates, maintains or increases the rate of developmental growth." [GOC:go_curators] synonym: "activation of developmental growth" NARROW [] synonym: "stimulation of developmental growth" NARROW [] synonym: "up regulation of developmental growth" EXACT [] synonym: "up-regulation of developmental growth" EXACT [] synonym: "upregulation of developmental growth" EXACT [] is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048589 ! positively regulates developmental growth relationship: RO:0002213 GO:0048589 ! positively regulates developmental growth [Term] id: GO:0048640 name: negative regulation of developmental growth def: "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." [GOC:go_curators] synonym: "down regulation of developmental growth" EXACT [] synonym: "down-regulation of developmental growth" EXACT [] synonym: "downregulation of developmental growth" EXACT [] synonym: "inhibition of developmental growth" NARROW [] is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048589 ! negatively regulates developmental growth relationship: RO:0002212 GO:0048589 ! negatively regulates developmental growth [Term] id: GO:0048641 name: regulation of skeletal muscle tissue development def: "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007519 ! regulates skeletal muscle tissue development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0007519 ! regulates skeletal muscle tissue development [Term] id: GO:0048642 name: negative regulation of skeletal muscle tissue development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] synonym: "down regulation of skeletal muscle development" EXACT [] synonym: "down-regulation of skeletal muscle development" EXACT [] synonym: "downregulation of skeletal muscle development" EXACT [] synonym: "inhibition of skeletal muscle development" NARROW [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007519 ! negatively regulates skeletal muscle tissue development relationship: RO:0002212 GO:0007519 ! negatively regulates skeletal muscle tissue development [Term] id: GO:0048643 name: positive regulation of skeletal muscle tissue development def: "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." [GOC:go_curators] synonym: "activation of skeletal muscle development" NARROW [] synonym: "stimulation of skeletal muscle development" NARROW [] synonym: "up regulation of skeletal muscle development" EXACT [] synonym: "up-regulation of skeletal muscle development" EXACT [] synonym: "upregulation of skeletal muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007519 ! positively regulates skeletal muscle tissue development relationship: RO:0002213 GO:0007519 ! positively regulates skeletal muscle tissue development [Term] id: GO:0048644 name: muscle organ morphogenesis def: "The process in which the anatomical structures of muscle are generated and organized." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001630 ! results in morphogenesis of muscle organ relationship: part_of GO:0007517 ! muscle organ development relationship: RO:0002298 UBERON:0001630 ! results in morphogenesis of muscle organ [Term] id: GO:0048645 name: animal organ formation def: "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." [GOC:dph, GOC:jid] synonym: "animal organ primordium initiation" NARROW [] synonym: "initiation of an animal organ primordium" NARROW [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003103 ! results in formation of anatomical entity compound organ relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: RO:0002297 UBERON:0003103 ! results in formation of anatomical entity compound organ [Term] id: GO:0048646 name: anatomical structure formation involved in morphogenesis def: "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:jid, GOC:tb] comment: Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense. subset: goslim_chembl synonym: "formation of an anatomical structure involved in morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0032502 ! developmental process relationship: part_of GO:0009653 ! anatomical structure morphogenesis [Term] id: GO:0048659 name: smooth muscle cell proliferation def: "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." [CL:0000192, GOC:ebc, PMID:1840698] synonym: "SMC proliferation" EXACT [] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000192 ! acts on population of smooth muscle cell relationship: RO:0012003 CL:0000192 ! acts on population of smooth muscle cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048660 name: regulation of smooth muscle cell proliferation def: "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "regulation of SMC proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048659 ! regulates smooth muscle cell proliferation relationship: RO:0002211 GO:0048659 ! regulates smooth muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048661 name: positive regulation of smooth muscle cell proliferation def: "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "activation of smooth muscle cell proliferation" NARROW [] synonym: "positive regulation of SMC proliferation" EXACT [] synonym: "stimulation of smooth muscle cell proliferation" NARROW [] synonym: "up regulation of smooth muscle cell proliferation" EXACT [] synonym: "up-regulation of smooth muscle cell proliferation" EXACT [] synonym: "upregulation of smooth muscle cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048659 ! positively regulates smooth muscle cell proliferation relationship: RO:0002213 GO:0048659 ! positively regulates smooth muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048662 name: negative regulation of smooth muscle cell proliferation def: "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "down regulation of smooth muscle cell proliferation" EXACT [] synonym: "down-regulation of smooth muscle cell proliferation" EXACT [] synonym: "downregulation of smooth muscle cell proliferation" EXACT [] synonym: "inhibition of smooth muscle cell proliferation" NARROW [] synonym: "negative regulation of SMC proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048659 ! negatively regulates smooth muscle cell proliferation relationship: RO:0002212 GO:0048659 ! negatively regulates smooth muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0048666 name: neuron development def: "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000540 ! results in development of neuron relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0030182 ! neuron differentiation relationship: RO:0002296 CL:0000540 ! results in development of neuron [Term] id: GO:0048667 name: cell morphogenesis involved in neuron differentiation def: "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." [GOC:dph, GOC:tb] synonym: "neuron morphogenesis involved in differentiation" EXACT [GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0000902 ! cell morphogenesis intersection_of: part_of GO:0030182 ! neuron differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048666 ! neuron development [Term] id: GO:0048699 name: generation of neurons def: "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." [GOC:nln] synonym: "neuron generation" EXACT [] is_a: GO:0022008 ! neurogenesis [Term] id: GO:0048705 name: skeletal system morphogenesis def: "The process in which the anatomical structures of the skeleton are generated and organized." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb] synonym: "skeletal morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001434 ! results in morphogenesis of skeletal system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0001501 ! skeletal system development relationship: RO:0002298 UBERON:0001434 ! results in morphogenesis of skeletal system [Term] id: GO:0048709 name: oligodendrocyte differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system." [GOC:vp, PMID:15139015] is_a: GO:0010001 ! glial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000128 ! results in acquisition of features of oligodendrocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007417 ! central nervous system development relationship: RO:0002315 CL:0000128 ! results in acquisition of features of oligodendrocyte [Term] id: GO:0048713 name: regulation of oligodendrocyte differentiation def: "Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048709 ! regulates oligodendrocyte differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0048709 ! regulates oligodendrocyte differentiation [Term] id: GO:0048714 name: positive regulation of oligodendrocyte differentiation def: "Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "activation of oligodendrocyte differentiation" NARROW [] synonym: "stimulation of oligodendrocyte differentiation" NARROW [] synonym: "up regulation of oligodendrocyte differentiation" EXACT [] synonym: "up-regulation of oligodendrocyte differentiation" EXACT [] synonym: "upregulation of oligodendrocyte differentiation" EXACT [] is_a: GO:0045687 ! positive regulation of glial cell differentiation is_a: GO:0048713 ! regulation of oligodendrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048709 ! positively regulates oligodendrocyte differentiation relationship: RO:0002213 GO:0048709 ! positively regulates oligodendrocyte differentiation [Term] id: GO:0048715 name: negative regulation of oligodendrocyte differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "down regulation of oligodendrocyte differentiation" EXACT [] synonym: "down-regulation of oligodendrocyte differentiation" EXACT [] synonym: "downregulation of oligodendrocyte differentiation" EXACT [] synonym: "inhibition of oligodendrocyte differentiation" NARROW [] is_a: GO:0045686 ! negative regulation of glial cell differentiation is_a: GO:0048713 ! regulation of oligodendrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048709 ! negatively regulates oligodendrocyte differentiation relationship: RO:0002212 GO:0048709 ! negatively regulates oligodendrocyte differentiation [Term] id: GO:0048729 name: tissue morphogenesis def: "The process in which the anatomical structures of a tissue are generated and organized." [GOC:dph, GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000479 ! results in morphogenesis of tissue relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0009888 ! tissue development relationship: RO:0002298 UBERON:0000479 ! results in morphogenesis of tissue property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0048730 name: epidermis morphogenesis def: "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:jid, UBERON:0001003] synonym: "hypodermis morphogenesis" RELATED [GOC:kmv, GOC:rk] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007376 ! results in morphogenesis of outer epithelium relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0008544 ! epidermis development relationship: RO:0002298 UBERON:0007376 ! results in morphogenesis of outer epithelium [Term] id: GO:0048731 name: system development namespace: biological_process def: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid] subset: goslim_mouse is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000467 ! results in development of anatomical system relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0007275 ! multicellular organism development relationship: RO:0002296 UBERON:0000467 ! results in development of anatomical system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048732 name: gland development namespace: biological_process def: "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." [GOC:jid] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002530 ! results in development of gland relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0002530 ! results in development of gland [Term] id: GO:0048736 name: appendage development def: "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [GOC:jid, GOC:rc] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000026 ! results in development of appendage relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007275 ! multicellular organism development relationship: RO:0002296 UBERON:0000026 ! results in development of appendage [Term] id: GO:0048738 name: cardiac muscle tissue development def: "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] synonym: "heart muscle development" EXACT [] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001133 ! results in development of cardiac muscle tissue relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007507 ! heart development relationship: RO:0002296 UBERON:0001133 ! results in development of cardiac muscle tissue [Term] id: GO:0048741 name: skeletal muscle fiber development def: "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:ef, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "skeletal muscle fibre development" EXACT [] synonym: "skeletal myofiber development" EXACT [] synonym: "skeletal myofibre development" EXACT [] is_a: GO:0014904 ! myotube cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0008002 ! results in development of skeletal muscle fiber relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: RO:0002296 CL:0008002 ! results in development of skeletal muscle fiber [Term] id: GO:0048742 name: regulation of skeletal muscle fiber development def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:mtg_muscle, GOC:sm] synonym: "regulation of skeletal muscle fibre development" EXACT [] synonym: "regulation of skeletal myofiber development" EXACT [] synonym: "regulation of skeletal myofibre development" EXACT [] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048741 ! regulates skeletal muscle fiber development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0048741 ! regulates skeletal muscle fiber development [Term] id: GO:0048743 name: positive regulation of skeletal muscle fiber development def: "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "activation of skeletal muscle fiber development" NARROW [] synonym: "positive regulation of skeletal muscle fibre development" EXACT [] synonym: "positive regulation of skeletal myofiber development" EXACT [] synonym: "positive regulation of skeletal myofibre development" EXACT [] synonym: "stimulation of skeletal muscle fiber development" NARROW [] synonym: "up regulation of skeletal muscle fiber development" EXACT [] synonym: "up-regulation of skeletal muscle fiber development" EXACT [] synonym: "upregulation of skeletal muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048741 ! positively regulates skeletal muscle fiber development relationship: RO:0002213 GO:0048741 ! positively regulates skeletal muscle fiber development [Term] id: GO:0048744 name: negative regulation of skeletal muscle fiber development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "down regulation of skeletal muscle fiber development" EXACT [] synonym: "down-regulation of skeletal muscle fiber development" EXACT [] synonym: "downregulation of skeletal muscle fiber development" EXACT [] synonym: "inhibition of skeletal muscle fiber development" NARROW [] synonym: "negative regulation of skeletal muscle fibre development" EXACT [] synonym: "negative regulation of skeletal myofiber development" EXACT [] synonym: "negative regulation of skeletal myofibre development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048741 ! negatively regulates skeletal muscle fiber development relationship: RO:0002212 GO:0048741 ! negatively regulates skeletal muscle fiber development [Term] id: GO:0048745 name: smooth muscle tissue development def: "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001135 ! results in development of smooth muscle tissue relationship: RO:0002296 UBERON:0001135 ! results in development of smooth muscle tissue [Term] id: GO:0048749 name: compound eye development alt_id: GO:0007456 def: "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." [GOC:jid, GOC:mtg_sensu, Wikipedia:Eye] synonym: "insect-type retina development" EXACT [PMID:11735386] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000018 ! results in development of compound eye relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: RO:0002296 UBERON:0000018 ! results in development of compound eye [Term] id: GO:0048753 name: pigment granule organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." [GOC:rc] subset: goslim_pir synonym: "pigment granule organisation" EXACT [] synonym: "pigment granule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0048770 ! results in organization of pigment granule relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0033059 ! cellular pigmentation relationship: RO:0002592 GO:0048770 ! results in organization of pigment granule [Term] id: GO:0048754 name: branching morphogenesis of an epithelial tube def: "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." [GOC:dgh, GOC:dph, GOC:jid] synonym: "tubulogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0035239 ! tube morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: RO:0002298 UBERON:0000025 ! results in morphogenesis of tube relationship: part_of GO:0060562 ! epithelial tube morphogenesis [Term] id: GO:0048755 name: branching morphogenesis of a nerve def: "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." [GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001763 ! morphogenesis of a branching structure intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: RO:0002298 UBERON:0001021 ! results in morphogenesis of nerve relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002298 UBERON:0001021 ! results in morphogenesis of nerve [Term] id: GO:0048762 name: mesenchymal cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008019 ! results in acquisition of features of mesenchymal cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0060485 ! mesenchyme development relationship: RO:0002315 CL:0008019 ! results in acquisition of features of mesenchymal cell [Term] id: GO:0048770 name: pigment granule def: "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." [GOC:jid, GOC:mh] is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0048793 name: pronephros development def: "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:bf, GOC:mtg_kidney_jan10, PMID:10535314, PMID:15968585, PMID:18322540, XAO:00002000, ZFA:0000151] synonym: "pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002120 ! results in development of pronephros relationship: RO:0002296 UBERON:0002120 ! results in development of pronephros [Term] id: GO:0048799 name: animal organ maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." [GOC:curators] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0000062 ! results in maturation of organ relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0048513 ! animal organ development relationship: RO:0002299 UBERON:0000062 ! results in maturation of organ [Term] id: GO:0048806 name: genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." [GOC:jid] synonym: "genital development" EXACT [] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development relationship: part_of GO:0007548 ! sex differentiation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048808 name: male genitalia morphogenesis def: "The process in which the anatomical structures of male genitalia are generated and organized." [GOC:ems, ISBN:0140512888] synonym: "male genital morphogenesis" RELATED [] is_a: GO:0035112 ! genitalia morphogenesis is_a: GO:0090598 ! male anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000079 ! results in morphogenesis of male reproductive system relationship: part_of GO:0030539 ! male genitalia development relationship: RO:0002298 UBERON:0000079 ! results in morphogenesis of male reproductive system [Term] id: GO:0048812 name: neuron projection morphogenesis def: "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:mah] synonym: "neurite biosynthesis" NARROW [] synonym: "neurite formation" NARROW [] synonym: "neurite growth" NARROW [] synonym: "neurite morphogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0043005 ! results in morphogenesis of neuron projection relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0031175 ! neuron projection development relationship: RO:0002298 GO:0043005 ! results in morphogenesis of neuron projection [Term] id: GO:0048820 name: hair follicle maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state." [GOC:devbiol] is_a: GO:0022405 ! hair cycle process is_a: GO:0071695 ! anatomical structure maturation relationship: part_of GO:0001942 ! hair follicle development [Term] id: GO:0048821 name: erythrocyte development def: "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." [GOC:devbiol] synonym: "RBC development" EXACT [CL:0000232] synonym: "red blood cell development" EXACT [CL:0000232] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000232 ! results in development of erythrocyte relationship: part_of GO:0030218 ! erythrocyte differentiation relationship: RO:0002296 CL:0000232 ! results in development of erythrocyte [Term] id: GO:0048823 name: nucleate erythrocyte development def: "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] synonym: "nucleate RBC development" EXACT [CL:0000232] synonym: "nucleate red blood cell development" EXACT [CL:0000232] is_a: GO:0048821 ! erythrocyte development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000562 ! results in development of nucleate erythrocyte relationship: part_of GO:0043363 ! nucleate erythrocyte differentiation relationship: RO:0002296 CL:0000562 ! results in development of nucleate erythrocyte [Term] id: GO:0048839 name: inner ear development def: "The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure." [GOC:sr] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001846 ! results in development of internal ear relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043583 ! ear development relationship: RO:0002296 UBERON:0001846 ! results in development of internal ear [Term] id: GO:0048844 name: artery morphogenesis def: "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." [GOC:dsf, PMID:16740480] synonym: "arterial morphogenesis" EXACT [] synonym: "arteriogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001637 ! results in morphogenesis of artery relationship: part_of GO:0060840 ! artery development relationship: RO:0002298 UBERON:0001637 ! results in morphogenesis of artery [Term] id: GO:0048845 name: venous blood vessel morphogenesis def: "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." [GOC:dsf, PMID:16740480] synonym: "vein morphogenesis" BROAD [] synonym: "venous morphogenesis" EXACT [] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001638 ! results in morphogenesis of vein relationship: part_of GO:0060841 ! venous blood vessel development relationship: RO:0002298 UBERON:0001638 ! results in morphogenesis of vein [Term] id: GO:0048853 name: forebrain morphogenesis def: "The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." [GOC:cvs, GOC:dgh, GOC:dph, GOC:jid] synonym: "prosencephalon morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001890 ! results in morphogenesis of forebrain relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0030900 ! forebrain development relationship: part_of GO:0048854 ! brain morphogenesis relationship: RO:0002298 UBERON:0001890 ! results in morphogenesis of forebrain [Term] id: GO:0048854 name: brain morphogenesis def: "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dgh, GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000955 ! results in morphogenesis of brain relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007420 ! brain development relationship: RO:0002298 UBERON:0000955 ! results in morphogenesis of brain [Term] id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant subset: goslim_plant_ribbon synonym: "development of an anatomical structure" EXACT [] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 UBERON:0000061 ! results in development of anatomical structure relationship: RO:0002296 UBERON:0000061 ! results in development of anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048857 name: neural nucleus development def: "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." [GO_REF:0000021] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000125 ! results in development of neural nucleus relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002296 UBERON:0000125 ! results in development of neural nucleus [Term] id: GO:0048858 name: cell projection morphogenesis def: "The process in which the anatomical structures of a cell projection are generated and organized." [GO_REF:0000021] is_a: GO:0009653 ! anatomical structure morphogenesis is_a: GO:0030030 ! cell projection organization intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0042995 ! results in morphogenesis of cell projection relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0000902 ! cell morphogenesis relationship: RO:0002298 GO:0042995 ! results in morphogenesis of cell projection [Term] id: GO:0048859 name: formation of anatomical boundary def: "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0007651 ! results in formation of anatomical entity anatomical junction relationship: RO:0002297 UBERON:0007651 ! results in formation of anatomical entity anatomical junction [Term] id: GO:0048860 name: glioblast division def: "The process resulting in the physical partitioning and separation of a glioblast into daughter cells." [GOC:devbiol] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000030 ! has primary input glioblast relationship: RO:0004009 CL:0000030 ! has primary input glioblast [Term] id: GO:0048863 name: stem cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034, GOC:isa_complete] xref: Wikipedia:Stem_cell_differentiation is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000034 ! results in acquisition of features of stem cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002315 CL:0000034 ! results in acquisition of features of stem cell [Term] id: GO:0048864 name: stem cell development def: "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." [CL:0000034, GOC:isa_complete] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000034 ! results in development of stem cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048863 ! stem cell differentiation relationship: RO:0002296 CL:0000034 ! results in development of stem cell [Term] id: GO:0048869 name: cellular developmental process def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] is_a: GO:0009987 ! cellular process is_a: GO:0032502 ! developmental process [Term] id: GO:0048870 name: cell motility def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg] subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] is_a: GO:0009987 ! cellular process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0048871 name: multicellular organismal-level homeostasis def: "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." [GOC:isa_complete] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0042592 ! homeostatic process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048872 name: homeostasis of number of cells def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." [GOC:isa_complete] synonym: "cell population homeostasis" EXACT [] synonym: "homeostasis of cell number" EXACT [GOC:dph] is_a: GO:0048871 ! multicellular organismal-level homeostasis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0048878 name: chemical homeostasis def: "Any biological process involved in the maintenance of an internal steady state of a chemical." [GOC:isa_complete] subset: goslim_drosophila is_a: GO:0042592 ! homeostatic process intersection_of: GO:0042592 ! homeostatic process intersection_of: RO:0002332 CHEBI:24431 ! regulates levels of chemical entity relationship: RO:0002332 CHEBI:24431 ! regulates levels of chemical entity [Term] id: GO:0048880 name: sensory system development def: "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." [GOC:dgh] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001032 ! results in development of sensory system relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0001032 ! results in development of sensory system [Term] id: GO:0048934 name: peripheral nervous system neuron differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." [GOC:dgh] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:2000032 ! results in acquisition of features of peripheral nervous system neuron relationship: part_of GO:0007422 ! peripheral nervous system development relationship: RO:0002315 CL:2000032 ! results in acquisition of features of peripheral nervous system neuron [Term] id: GO:0048935 name: peripheral nervous system neuron development def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GOC:dgh] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:2000032 ! results in development of peripheral nervous system neuron relationship: part_of GO:0048934 ! peripheral nervous system neuron differentiation relationship: RO:0002296 CL:2000032 ! results in development of peripheral nervous system neuron [Term] id: GO:0050000 name: chromosome localization def: "Any process in which a chromosome is transported to, or maintained in, a specific location." [GOC:ai] synonym: "chromosome localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of chromosome localization" EXACT [] synonym: "establishment and maintenance of chromosome position" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005694 ! has primary input chromosome relationship: RO:0004009 GO:0005694 ! has primary input chromosome [Term] id: GO:0050432 name: catecholamine secretion def: "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, GOC:ef] is_a: GO:0032940 ! secretion by cell is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine [Term] id: GO:0050433 name: regulation of catecholamine secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." [GOC:ai] is_a: GO:0051952 ! regulation of amine transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050432 ! regulates catecholamine secretion relationship: RO:0002211 GO:0050432 ! regulates catecholamine secretion [Term] id: GO:0050657 name: nucleic acid transport def: "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] is_a: GO:0015931 ! nucleobase-containing compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33696 ! has primary input nucleic acid relationship: RO:0004009 CHEBI:33696 ! has primary input nucleic acid [Term] id: GO:0050658 name: RNA transport def: "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050657 ! nucleic acid transport is_a: GO:0051236 ! establishment of RNA localization intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0050670 name: regulation of lymphocyte proliferation def: "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." [GOC:ai] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046651 ! regulates lymphocyte proliferation relationship: RO:0002211 GO:0046651 ! regulates lymphocyte proliferation [Term] id: GO:0050671 name: positive regulation of lymphocyte proliferation def: "Any process that activates or increases the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "activation of lymphocyte proliferation" NARROW [] synonym: "stimulation of lymphocyte proliferation" NARROW [] synonym: "up regulation of lymphocyte proliferation" EXACT [] synonym: "up-regulation of lymphocyte proliferation" EXACT [] synonym: "upregulation of lymphocyte proliferation" EXACT [] is_a: GO:0032946 ! positive regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051251 ! positive regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046651 ! positively regulates lymphocyte proliferation relationship: RO:0002213 GO:0046651 ! positively regulates lymphocyte proliferation [Term] id: GO:0050672 name: negative regulation of lymphocyte proliferation def: "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "down regulation of lymphocyte proliferation" EXACT [] synonym: "down-regulation of lymphocyte proliferation" EXACT [] synonym: "downregulation of lymphocyte proliferation" EXACT [] synonym: "inhibition of lymphocyte proliferation" NARROW [] is_a: GO:0032945 ! negative regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051250 ! negative regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046651 ! negatively regulates lymphocyte proliferation relationship: RO:0002212 GO:0046651 ! negatively regulates lymphocyte proliferation [Term] id: GO:0050673 name: epithelial cell proliferation def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." [ISBN:0721662544] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000066 ! acts on population of epithelial cell relationship: RO:0012003 CL:0000066 ! acts on population of epithelial cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0050678 name: regulation of epithelial cell proliferation def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." [GOC:ai] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050673 ! regulates epithelial cell proliferation relationship: RO:0002211 GO:0050673 ! regulates epithelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0050679 name: positive regulation of epithelial cell proliferation def: "Any process that activates or increases the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "activation of epithelial cell proliferation" NARROW [] synonym: "stimulation of epithelial cell proliferation" NARROW [] synonym: "up regulation of epithelial cell proliferation" EXACT [] synonym: "up-regulation of epithelial cell proliferation" EXACT [] synonym: "upregulation of epithelial cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050673 ! positively regulates epithelial cell proliferation relationship: RO:0002213 GO:0050673 ! positively regulates epithelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0050680 name: negative regulation of epithelial cell proliferation def: "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "down regulation of epithelial cell proliferation" EXACT [] synonym: "down-regulation of epithelial cell proliferation" EXACT [] synonym: "downregulation of epithelial cell proliferation" EXACT [] synonym: "inhibition of epithelial cell proliferation" NARROW [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050673 ! negatively regulates epithelial cell proliferation relationship: RO:0002212 GO:0050673 ! negatively regulates epithelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0050708 name: regulation of protein secretion def: "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009306 ! regulates protein secretion relationship: RO:0002211 GO:0009306 ! regulates protein secretion [Term] id: GO:0050709 name: negative regulation of protein secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "down regulation of protein secretion" EXACT [] synonym: "down-regulation of protein secretion" EXACT [] synonym: "downregulation of protein secretion" EXACT [] synonym: "inhibition of protein secretion" NARROW [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009306 ! negatively regulates protein secretion relationship: RO:0002212 GO:0009306 ! negatively regulates protein secretion [Term] id: GO:0050714 name: positive regulation of protein secretion def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "activation of protein secretion" NARROW [] synonym: "stimulation of protein secretion" NARROW [] synonym: "up regulation of protein secretion" EXACT [] synonym: "up-regulation of protein secretion" EXACT [] synonym: "upregulation of protein secretion" EXACT [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009306 ! positively regulates protein secretion relationship: RO:0002213 GO:0009306 ! positively regulates protein secretion [Term] id: GO:0050727 name: regulation of inflammatory response def: "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." [GOC:ai] is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006954 ! regulates inflammatory response relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0006954 ! regulates inflammatory response [Term] id: GO:0050728 name: negative regulation of inflammatory response alt_id: GO:0030236 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "anti-inflammatory response" EXACT [] synonym: "down regulation of inflammatory response" EXACT [] synonym: "down-regulation of inflammatory response" EXACT [] synonym: "downregulation of inflammatory response" EXACT [] synonym: "inhibition of inflammatory response" NARROW [] xref: Reactome:R-HSA-9018678 "Biosynthesis of specialized proresolving mediators (SPMs)" is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006954 ! negatively regulates inflammatory response relationship: RO:0002212 GO:0006954 ! negatively regulates inflammatory response [Term] id: GO:0050729 name: positive regulation of inflammatory response def: "Any process that activates or increases the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "activation of inflammatory response" NARROW [] synonym: "stimulation of inflammatory response" NARROW [] synonym: "up regulation of inflammatory response" EXACT [] synonym: "up-regulation of inflammatory response" EXACT [] synonym: "upregulation of inflammatory response" EXACT [] is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006954 ! positively regulates inflammatory response relationship: RO:0002213 GO:0006954 ! positively regulates inflammatory response [Term] id: GO:0050764 name: regulation of phagocytosis def: "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." [GOC:ai] is_a: GO:0030100 ! regulation of endocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006909 ! regulates phagocytosis relationship: RO:0002211 GO:0006909 ! regulates phagocytosis property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0050765 name: negative regulation of phagocytosis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "down regulation of phagocytosis" EXACT [] synonym: "down-regulation of phagocytosis" EXACT [] synonym: "downregulation of phagocytosis" EXACT [] synonym: "inhibition of phagocytosis" NARROW [] is_a: GO:0045806 ! negative regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006909 ! negatively regulates phagocytosis relationship: RO:0002212 GO:0006909 ! negatively regulates phagocytosis property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0050766 name: positive regulation of phagocytosis def: "Any process that activates or increases the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "activation of phagocytosis" NARROW [] synonym: "stimulation of phagocytosis" NARROW [] synonym: "up regulation of phagocytosis" EXACT [] synonym: "up-regulation of phagocytosis" EXACT [] synonym: "upregulation of phagocytosis" EXACT [] is_a: GO:0045807 ! positive regulation of endocytosis is_a: GO:0050764 ! regulation of phagocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006909 ! positively regulates phagocytosis relationship: RO:0002213 GO:0006909 ! positively regulates phagocytosis property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0050767 name: regulation of neurogenesis def: "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." [GOC:ai] is_a: GO:0051960 ! regulation of nervous system development is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022008 ! regulates neurogenesis relationship: RO:0002211 GO:0022008 ! regulates neurogenesis [Term] id: GO:0050768 name: negative regulation of neurogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "down regulation of neurogenesis" EXACT [] synonym: "down-regulation of neurogenesis" EXACT [] synonym: "downregulation of neurogenesis" EXACT [] synonym: "inhibition of neurogenesis" NARROW [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051961 ! negative regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022008 ! negatively regulates neurogenesis relationship: RO:0002212 GO:0022008 ! negatively regulates neurogenesis [Term] id: GO:0050769 name: positive regulation of neurogenesis def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "activation of neurogenesis" NARROW [] synonym: "stimulation of neurogenesis" NARROW [] synonym: "up regulation of neurogenesis" EXACT [] synonym: "up-regulation of neurogenesis" EXACT [] synonym: "upregulation of neurogenesis" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051962 ! positive regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022008 ! positively regulates neurogenesis relationship: RO:0002213 GO:0022008 ! positively regulates neurogenesis [Term] id: GO:0050770 name: regulation of axonogenesis def: "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." [GOC:ai] xref: Reactome:R-HSA-193697 "p75NTR regulates axonogenesis" is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007409 ! regulates axonogenesis relationship: RO:0002211 GO:0007409 ! regulates axonogenesis [Term] id: GO:0050771 name: negative regulation of axonogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." [GOC:ai] synonym: "down regulation of axonogenesis" EXACT [] synonym: "down-regulation of axonogenesis" EXACT [] synonym: "downregulation of axonogenesis" EXACT [] synonym: "inhibition of axonogenesis" NARROW [] xref: Reactome:R-HSA-193634 "Axonal growth inhibition (RHOA activation)" is_a: GO:0010977 ! negative regulation of neuron projection development is_a: GO:0050768 ! negative regulation of neurogenesis is_a: GO:0050770 ! regulation of axonogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007409 ! negatively regulates axonogenesis relationship: RO:0002212 GO:0007409 ! negatively regulates axonogenesis [Term] id: GO:0050772 name: positive regulation of axonogenesis def: "Any process that activates or increases the frequency, rate or extent of axonogenesis." [GOC:ai] synonym: "activation of axonogenesis" NARROW [] synonym: "stimulation of axonogenesis" NARROW [] synonym: "up regulation of axonogenesis" EXACT [] synonym: "up-regulation of axonogenesis" EXACT [] synonym: "upregulation of axonogenesis" EXACT [] xref: Reactome:R-HSA-209563 "Axonal growth stimulation" is_a: GO:0031346 ! positive regulation of cell projection organization is_a: GO:0050769 ! positive regulation of neurogenesis is_a: GO:0050770 ! regulation of axonogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007409 ! positively regulates axonogenesis relationship: RO:0002213 GO:0007409 ! positively regulates axonogenesis [Term] id: GO:0050776 name: regulation of immune response def: "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] xref: Reactome:R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006955 ! regulates immune response relationship: RO:0002211 GO:0006955 ! regulates immune response property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0050777 name: negative regulation of immune response def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "down regulation of immune response" EXACT [] synonym: "down-regulation of immune response" EXACT [] synonym: "downregulation of immune response" EXACT [] synonym: "inhibition of immune response" NARROW [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006955 ! negatively regulates immune response relationship: RO:0002212 GO:0006955 ! negatively regulates immune response property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0050778 name: positive regulation of immune response def: "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "stimulation of immune response" NARROW [] synonym: "up regulation of immune response" EXACT [] synonym: "up-regulation of immune response" EXACT [] synonym: "upregulation of immune response" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006955 ! positively regulates immune response relationship: RO:0002213 GO:0006955 ! positively regulates immune response property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0050789 name: regulation of biological process alt_id: GO:0050791 def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_pir synonym: "regulation of physiological process" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008150 ! regulates biological process relationship: RO:0002211 GO:0008150 ! regulates biological process [Term] id: GO:0050790 name: regulation of catalytic activity alt_id: GO:0048552 def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw] subset: gocheck_obsoletion_candidate subset: goslim_chembl synonym: "regulation of enzyme activity" EXACT [] synonym: "regulation of metalloenzyme activity" NARROW [] is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003824 ! regulates catalytic activity relationship: RO:0002211 GO:0003824 ! regulates catalytic activity [Term] id: GO:0050793 name: regulation of developmental process def: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032502 ! regulates developmental process relationship: RO:0002211 GO:0032502 ! regulates developmental process [Term] id: GO:0050794 name: regulation of cellular process alt_id: GO:0051244 def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] subset: gocheck_do_not_annotate synonym: "regulation of cellular physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009987 ! regulates cellular process relationship: RO:0002211 GO:0009987 ! regulates cellular process [Term] id: GO:0050795 name: regulation of behavior def: "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:go_curators, GOC:pr] synonym: "regulation of behaviour" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007610 ! regulates behavior relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0007610 ! regulates behavior [Term] id: GO:0050796 name: regulation of insulin secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin." [GOC:ai] xref: Reactome:R-HSA-422356 "Regulation of insulin secretion" is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030073 ! regulates insulin secretion relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0030073 ! regulates insulin secretion [Term] id: GO:0050801 name: monoatomic ion homeostasis alt_id: GO:2000021 def: "Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:ai] synonym: "electrolyte homeostasis" RELATED [] synonym: "ion homeostasis" BROAD [] synonym: "negative regulation of crystal formation" RELATED [] synonym: "regulation of ion homeostasis" RELATED [] is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:24867 ! regulates levels of monoatomic ion relationship: RO:0002332 CHEBI:24867 ! regulates levels of monoatomic ion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] id: GO:0050803 name: regulation of synapse structure or activity def: "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai] is_a: GO:0065008 ! regulation of biological quality relationship: in_taxon NCBITaxon:6072 ! Eumetazoa [Term] id: GO:0050804 name: modulation of chemical synaptic transmission def: "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." [GOC:ai] subset: goslim_synapse synonym: "modulation of synaptic transmission" BROAD [] synonym: "regulation of chemical synaptic transmission" EXACT [] synonym: "regulation of synaptic transmission" EXACT [] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission relationship: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0050805 name: negative regulation of synaptic transmission def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "down regulation of synaptic transmission" EXACT [] synonym: "down-regulation of synaptic transmission" EXACT [] synonym: "downregulation of synaptic transmission" EXACT [] synonym: "inhibition of synaptic transmission" NARROW [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007268 ! negatively regulates chemical synaptic transmission relationship: RO:0002212 GO:0007268 ! negatively regulates chemical synaptic transmission [Term] id: GO:0050806 name: positive regulation of synaptic transmission def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "activation of synaptic transmission" NARROW [] synonym: "stimulation of synaptic transmission" NARROW [] synonym: "up regulation of synaptic transmission" EXACT [] synonym: "up-regulation of synaptic transmission" EXACT [] synonym: "upregulation of synaptic transmission" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007268 ! positively regulates chemical synaptic transmission relationship: RO:0002213 GO:0007268 ! positively regulates chemical synaptic transmission [Term] id: GO:0050807 name: regulation of synapse organization def: "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of synapse organisation" EXACT [GOC:mah] synonym: "regulation of synapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of synapse structure" EXACT [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050808 ! regulates synapse organization relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0050803 ! regulation of synapse structure or activity relationship: RO:0002211 GO:0050808 ! regulates synapse organization [Term] id: GO:0050808 name: synapse organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:pr] subset: goslim_drosophila subset: goslim_synapse synonym: "synapse development" RELATED [GOC:aruk] synonym: "synapse morphogenesis" RELATED [GOC:BHF] synonym: "synapse organisation" EXACT [] synonym: "synapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0034330 ! cell junction organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0045202 ! results in organization of synapse relationship: RO:0002592 GO:0045202 ! results in organization of synapse [Term] id: GO:0050810 name: regulation of steroid biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:ai] synonym: "regulation of steroid anabolism" EXACT [] synonym: "regulation of steroid biosynthesis" EXACT [] synonym: "regulation of steroid formation" EXACT [] synonym: "regulation of steroid synthesis" EXACT [] synonym: "regulation of steroidogenesis" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006694 ! regulates steroid biosynthetic process relationship: RO:0002211 GO:0006694 ! regulates steroid biosynthetic process [Term] id: GO:0050817 name: coagulation def: "The process in which a fluid solution, or part of it, changes into a solid or semisolid mass." [ISBN:0198506732] subset: goslim_pir synonym: "clotting" EXACT [] is_a: GO:0032501 ! multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0050818 name: regulation of coagulation def: "Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass." [GOC:ai] synonym: "regulation of clotting" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050817 ! regulates coagulation relationship: RO:0002211 GO:0050817 ! regulates coagulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0050819 name: negative regulation of coagulation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation." [GOC:ai] synonym: "anticoagulant activity" RELATED [] synonym: "down regulation of coagulation" EXACT [] synonym: "down-regulation of coagulation" EXACT [] synonym: "downregulation of coagulation" EXACT [] synonym: "inhibition of coagulation" NARROW [] synonym: "negative regulation of clotting" EXACT [] is_a: GO:0050818 ! regulation of coagulation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050817 ! negatively regulates coagulation relationship: RO:0002212 GO:0050817 ! negatively regulates coagulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0050820 name: positive regulation of coagulation def: "Any process that activates or increases the frequency, rate or extent of coagulation." [GOC:ai] synonym: "activation of coagulation" NARROW [] synonym: "positive regulation of clotting" EXACT [] synonym: "stimulation of coagulation" NARROW [] synonym: "up regulation of coagulation" EXACT [] synonym: "up-regulation of coagulation" EXACT [] synonym: "upregulation of coagulation" EXACT [] is_a: GO:0050818 ! regulation of coagulation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050817 ! positively regulates coagulation relationship: RO:0002213 GO:0050817 ! positively regulates coagulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0050832 name: defense response to fungus alt_id: GO:0009623 alt_id: GO:0009817 alt_id: GO:0042831 def: "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai] synonym: "defence response to fungi" EXACT [] synonym: "defence response to fungus" EXACT [] synonym: "defense response to fungi" EXACT [] synonym: "defense response to fungus, incompatible interaction" NARROW [] synonym: "resistance response to pathogenic fungi" NARROW [] synonym: "resistance response to pathogenic fungus" NARROW [] synonym: "response to parasitic fungi" NARROW [] synonym: "response to parasitic fungus" NARROW [] is_a: GO:0006952 ! defense response is_a: GO:0009620 ! response to fungus intersection_of: GO:0006952 ! defense response intersection_of: RO:0004009 NCBITaxon:4751 ! has primary input Fungi property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0050863 name: regulation of T cell activation def: "Any process that modulates the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "regulation of T lymphocyte activation" EXACT [] synonym: "regulation of T-cell activation" EXACT [] synonym: "regulation of T-lymphocyte activation" EXACT [] is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042110 ! regulates T cell activation relationship: RO:0002211 GO:0042110 ! regulates T cell activation [Term] id: GO:0050865 name: regulation of cell activation def: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001775 ! regulates cell activation relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0001775 ! regulates cell activation [Term] id: GO:0050866 name: negative regulation of cell activation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." [GOC:ai] synonym: "down regulation of cell activation" EXACT [] synonym: "down-regulation of cell activation" EXACT [] synonym: "downregulation of cell activation" EXACT [] synonym: "inhibition of cell activation" NARROW [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001775 ! negatively regulates cell activation relationship: RO:0002212 GO:0001775 ! negatively regulates cell activation [Term] id: GO:0050867 name: positive regulation of cell activation def: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai] synonym: "activation of cell activation" NARROW [] synonym: "stimulation of cell activation" NARROW [] synonym: "up regulation of cell activation" EXACT [] synonym: "up-regulation of cell activation" EXACT [] synonym: "upregulation of cell activation" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001775 ! positively regulates cell activation relationship: RO:0002213 GO:0001775 ! positively regulates cell activation [Term] id: GO:0050868 name: negative regulation of T cell activation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "down regulation of T cell activation" EXACT [] synonym: "down-regulation of T cell activation" EXACT [] synonym: "downregulation of T cell activation" EXACT [] synonym: "inhibition of T cell activation" NARROW [] synonym: "negative regulation of T lymphocyte activation" EXACT [] synonym: "negative regulation of T-cell activation" EXACT [] synonym: "negative regulation of T-lymphocyte activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042110 ! negatively regulates T cell activation relationship: RO:0002212 GO:0042110 ! negatively regulates T cell activation [Term] id: GO:0050870 name: positive regulation of T cell activation def: "Any process that activates or increases the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "activation of T cell activation" NARROW [] synonym: "positive regulation of T lymphocyte activation" EXACT [] synonym: "positive regulation of T-cell activation" EXACT [] synonym: "positive regulation of T-lymphocyte activation" EXACT [] synonym: "stimulation of T cell activation" NARROW [] synonym: "up regulation of T cell activation" EXACT [] synonym: "up-regulation of T cell activation" EXACT [] synonym: "upregulation of T cell activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042110 ! positively regulates T cell activation relationship: RO:0002213 GO:0042110 ! positively regulates T cell activation [Term] id: GO:0050877 name: nervous system process def: "An organ system process carried out by any of the organs or tissues of the neurological system." [GOC:ai, GOC:mtg_cardio] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_pir synonym: "neurological system process" EXACT [] synonym: "neurophysiological process" EXACT [] synonym: "pan-neural process" RELATED [] is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: RO:0000057 UBERON:0001016 ! has participant nervous system relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0000057 UBERON:0001016 ! has participant nervous system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13824" xsd:anyURI [Term] id: GO:0050878 name: regulation of body fluid levels namespace: biological_process def: "Any process that modulates the levels of body fluids." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_pir is_a: GO:0065008 ! regulation of biological quality [Term] id: GO:0050879 name: multicellular organismal movement def: "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." [GOC:dph, GOC:mtg_muscle, GOC:tb] subset: goslim_pir is_a: GO:0032501 ! multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0050881 name: musculoskeletal movement def: "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." [GOC:dph] is_a: GO:0050879 ! multicellular organismal movement is_a: GO:0050905 ! neuromuscular process [Term] id: GO:0050886 name: endocrine process def: "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [ISBN:0721662544] subset: goslim_generic subset: goslim_pir synonym: "endocrine physiological process" EXACT [] synonym: "endocrine physiology" EXACT [] is_a: GO:0003008 ! system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0050890 name: cognition def: "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." [ISBN:0721619908] subset: goslim_drosophila xref: Wikipedia:Cognition is_a: GO:0050877 ! nervous system process [Term] id: GO:0050891 name: multicellular organismal-level water homeostasis def: "A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell." [GOC:dph, GOC:tb] synonym: "body fluid osmoregulation" RELATED [GOC:dph, GOC:tb] synonym: "multicellular organismal water homeostasis" EXACT [] is_a: GO:0050878 ! regulation of body fluid levels is_a: GO:0140962 ! multicellular organismal-level chemical homeostasis intersection_of: GO:0048871 ! multicellular organismal-level homeostasis intersection_of: RO:0002332 CHEBI:15377 ! regulates levels of water relationship: RO:0002332 CHEBI:15377 ! regulates levels of water property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24554" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0050896 name: response to stimulus namespace: biological_process alt_id: GO:0051869 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_prokaryote subset: goslim_prokaryote_ribbon synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological process [Term] id: GO:0050900 name: leukocyte migration def: "The movement of a leukocyte within or between different tissues and organs of the body." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration" EXACT [] synonym: "immune cell trafficking" EXACT [] synonym: "leucocyte migration" EXACT [] synonym: "leucocyte trafficking" EXACT [] synonym: "leukocyte trafficking" EXACT [] xref: Reactome:R-HSA-202733 "Cell surface interactions at the vascular wall" is_a: GO:0002376 ! immune system process is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000738 ! results in movement of leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002565 CL:0000738 ! results in movement of leukocyte [Term] id: GO:0050905 name: neuromuscular process def: "Any process pertaining to the functions of the nervous and muscular systems of an organism." [GOC:ai] synonym: "neuromotor process" EXACT [] synonym: "neuromuscular physiological process" EXACT [] is_a: GO:0050877 ! nervous system process [Term] id: GO:0050906 name: detection of stimulus involved in sensory perception def: "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph] synonym: "sensory detection of stimulus" EXACT [] synonym: "sensory perception, sensory transduction of stimulus" EXACT [] synonym: "sensory perception, stimulus detection" EXACT [] synonym: "sensory transduction" EXACT [] xref: Wikipedia:Transduction_(physiology) is_a: GO:0051606 ! detection of stimulus intersection_of: GO:0051606 ! detection of stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007600 ! sensory perception [Term] id: GO:0050907 name: detection of chemical stimulus involved in sensory perception def: "The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of chemical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus during sensory perception" EXACT [] is_a: GO:0009593 ! detection of chemical stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0007606 ! sensory perception of chemical stimulus [Term] id: GO:0050908 name: detection of light stimulus involved in visual perception def: "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "sensory detection of light during visual perception" EXACT [] synonym: "sensory detection of light stimulus during visual perception" EXACT [] synonym: "sensory transduction of light during visual perception" EXACT [] synonym: "sensory transduction of light stimulus during visual perception" EXACT [] synonym: "visual perception, detection of light stimulus" EXACT [] synonym: "visual perception, sensory transduction during perception of light" EXACT [] synonym: "visual perception, sensory transduction of light stimulus" EXACT [] is_a: GO:0050962 ! detection of light stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: part_of GO:0007601 ! visual perception relationship: part_of GO:0007601 ! visual perception [Term] id: GO:0050909 name: sensory perception of taste def: "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process." [GOC:ai] synonym: "gustation" EXACT [] synonym: "sense of taste" EXACT [] synonym: "taste" EXACT [] synonym: "taste perception" EXACT [] xref: Reactome:R-HSA-9717189 "Sensory perception of taste" xref: Wikipedia:Taste is_a: GO:0007606 ! sensory perception of chemical stimulus [Term] id: GO:0050910 name: detection of mechanical stimulus involved in sensory perception of sound alt_id: GO:0009592 alt_id: GO:0055128 def: "The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal." [GOC:ai] synonym: "detection of sound" EXACT [] synonym: "hearing, sensory transduction of sound" EXACT [] synonym: "perception of sound, detection of mechanical stimulus" EXACT [] synonym: "perception of sound, sensory detection of mechanical stimulus" EXACT [] synonym: "perception of sound, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during perception of sound" EXACT [] synonym: "sensory transduction of mechanical stimulus during perception of sound" EXACT [] synonym: "sensory transduction of sound" EXACT [] is_a: GO:0050877 ! nervous system process is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0007605 ! sensory perception of sound relationship: part_of GO:0007605 ! sensory perception of sound [Term] id: GO:0050911 name: detection of chemical stimulus involved in sensory perception of smell def: "The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "perception of smell, detection of chemical stimulus" EXACT [] synonym: "perception of smell, sensory detection of chemical stimulus" EXACT [] synonym: "perception of smell, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of smell" EXACT [] synonym: "sensory detection of scent" EXACT [] synonym: "sensory detection of smell" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of smell" EXACT [] synonym: "sensory transduction of scent" EXACT [] synonym: "sensory transduction of smell" EXACT [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0007608 ! sensory perception of smell relationship: part_of GO:0007608 ! sensory perception of smell [Term] id: GO:0050912 name: detection of chemical stimulus involved in sensory perception of taste def: "The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "perception of taste, detection of chemical stimulus" EXACT [] synonym: "perception of taste, sensory detection of chemical stimulus" EXACT [] synonym: "perception of taste, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of taste" EXACT [] synonym: "sensory detection of taste" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of taste" EXACT [] synonym: "sensory transduction of taste" EXACT [] synonym: "taste perception" BROAD [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0050909 ! sensory perception of taste relationship: part_of GO:0050909 ! sensory perception of taste [Term] id: GO:0050931 name: pigment cell differentiation alt_id: GO:0043357 alt_id: GO:0043358 def: "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." [GOC:dgh] comment: Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore. synonym: "chromatophore differentiation" EXACT [] synonym: "pigmented cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000147 ! results in acquisition of features of pigment cell relationship: part_of GO:0048066 ! developmental pigmentation relationship: RO:0002315 CL:0000147 ! results in acquisition of features of pigment cell [Term] id: GO:0050932 name: regulation of pigment cell differentiation def: "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." [GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050931 ! regulates pigment cell differentiation relationship: RO:0002211 GO:0050931 ! regulates pigment cell differentiation [Term] id: GO:0050941 name: negative regulation of pigment cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "down regulation of pigment cell differentiation" EXACT [] synonym: "down-regulation of pigment cell differentiation" EXACT [] synonym: "downregulation of pigment cell differentiation" EXACT [] synonym: "inhibition of pigment cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0048086 ! negative regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050931 ! negatively regulates pigment cell differentiation relationship: RO:0002212 GO:0050931 ! negatively regulates pigment cell differentiation [Term] id: GO:0050942 name: positive regulation of pigment cell differentiation def: "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "activation of pigment cell differentiation" NARROW [] synonym: "stimulation of pigment cell differentiation" NARROW [] synonym: "up regulation of pigment cell differentiation" EXACT [] synonym: "up-regulation of pigment cell differentiation" EXACT [] synonym: "upregulation of pigment cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0048087 ! positive regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050931 ! positively regulates pigment cell differentiation relationship: RO:0002213 GO:0050931 ! positively regulates pigment cell differentiation [Term] id: GO:0050952 name: sensory perception of electrical stimulus def: "The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050953 name: sensory perception of light stimulus def: "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050954 name: sensory perception of mechanical stimulus def: "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "chemi-mechanical coupling" RELATED [] synonym: "mechanosensory perception" EXACT [] synonym: "perception of mechanical stimulus" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050956 name: electroception def: "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location." [GOC:ai, PMID:10210663, Wikipedia:Electroreception] synonym: "electroception sense" EXACT [] synonym: "electroceptive sense" EXACT [] xref: Wikipedia:Electroreception is_a: GO:0050952 ! sensory perception of electrical stimulus [Term] id: GO:0050962 name: detection of light stimulus involved in sensory perception def: "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." [GOC:ai, GOC:dos] synonym: "sensory detection of light stimulus" EXACT [] synonym: "sensory detection of light stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of light stimulus" EXACT [] synonym: "sensory perception, sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus during sensory perception" EXACT [] is_a: GO:0009583 ! detection of light stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050953 ! sensory perception of light stimulus [Term] id: GO:0050963 name: detection of electrical stimulus involved in sensory perception def: "The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of electrical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus during sensory perception" EXACT [] is_a: GO:0050906 ! detection of stimulus involved in sensory perception is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050952 ! sensory perception of electrical stimulus [Term] id: GO:0050964 name: detection of electrical stimulus involved in electroception def: "The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "detection of electrical stimulus during electroreception" RELATED [GOC:dph, GOC:tb] synonym: "electroception, detection of electrical stimulus" EXACT [] synonym: "electroception, sensory detection of electrical stimulus" EXACT [] synonym: "electroception, sensory transduction" EXACT [] synonym: "electroception, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during electroception" RELATED [] synonym: "sensory transduction of electrical stimulus during electroception" RELATED [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0050956 ! electroception relationship: part_of GO:0050956 ! electroception [Term] id: GO:0050966 name: detection of mechanical stimulus involved in sensory perception of pain def: "The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "mechanical nociception" RELATED [GOC:pr] synonym: "perception of pain, detection of mechanical stimulus" EXACT [] synonym: "perception of pain, sensory detection of mechanical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during perception of pain" EXACT [] synonym: "sensory transduction of mechanical stimulus during perception of pain" EXACT [] is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050967 name: detection of electrical stimulus involved in sensory perception of pain def: "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "detection of electrical stimulus during sensory perception of pain" RELATED [GOC:dph, GOC:tb] synonym: "perception of pain, detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during perception of pain" RELATED [] synonym: "sensory transduction of electrical stimulus during perception of pain" RELATED [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050968 name: detection of chemical stimulus involved in sensory perception of pain def: "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "chemical nociception" RELATED [GOC:pr] synonym: "perception of pain, detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of pain" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of pain" EXACT [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050974 name: detection of mechanical stimulus involved in sensory perception def: "The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of mechanical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory transduction of mechanical stimulus during sensory perception" EXACT [] is_a: GO:0050906 ! detection of stimulus involved in sensory perception is_a: GO:0050982 ! detection of mechanical stimulus intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0050975 name: sensory perception of touch def: "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." [GOC:ai] synonym: "perception of touch" EXACT [] synonym: "tactile sense" EXACT [] synonym: "taction" EXACT [] synonym: "tactition" EXACT [] xref: Wikipedia:Touch is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0050976 name: detection of mechanical stimulus involved in sensory perception of touch def: "The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "perception of touch, detection of mechanical stimulus" EXACT [] synonym: "perception of touch, sensory detection of mechanical stimulus" EXACT [] synonym: "perception of touch, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during perception of touch" EXACT [] synonym: "sensory transduction of mechanical stimulus during perception of touch" EXACT [] synonym: "tactition, sensory detection of mechanical stimulus" EXACT [] is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0050975 ! sensory perception of touch relationship: part_of GO:0050975 ! sensory perception of touch [Term] id: GO:0050981 name: detection of electrical stimulus def: "The series of events by which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] is_a: GO:0009582 ! detection of abiotic stimulus is_a: GO:0051602 ! response to electrical stimulus [Term] id: GO:0050982 name: detection of mechanical stimulus def: "The series of events by which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] is_a: GO:0009581 ! detection of external stimulus is_a: GO:0009582 ! detection of abiotic stimulus is_a: GO:0009612 ! response to mechanical stimulus [Term] id: GO:0050994 name: regulation of lipid catabolic process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "regulation of lipid breakdown" EXACT [] synonym: "regulation of lipid catabolism" EXACT [] synonym: "regulation of lipid degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016042 ! regulates lipid catabolic process relationship: RO:0002211 GO:0016042 ! regulates lipid catabolic process [Term] id: GO:0050995 name: negative regulation of lipid catabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "down regulation of lipid catabolic process" EXACT [] synonym: "down-regulation of lipid catabolic process" EXACT [] synonym: "downregulation of lipid catabolic process" EXACT [] synonym: "inhibition of lipid catabolic process" NARROW [] synonym: "negative regulation of lipid breakdown" EXACT [] synonym: "negative regulation of lipid catabolism" EXACT [] synonym: "negative regulation of lipid degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016042 ! negatively regulates lipid catabolic process relationship: RO:0002212 GO:0016042 ! negatively regulates lipid catabolic process [Term] id: GO:0050996 name: positive regulation of lipid catabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "activation of lipid catabolic process" NARROW [] synonym: "positive regulation of lipid breakdown" EXACT [] synonym: "positive regulation of lipid catabolism" EXACT [] synonym: "positive regulation of lipid degradation" EXACT [] synonym: "stimulation of lipid catabolic process" NARROW [] synonym: "up regulation of lipid catabolic process" EXACT [] synonym: "up-regulation of lipid catabolic process" EXACT [] synonym: "upregulation of lipid catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016042 ! positively regulates lipid catabolic process relationship: RO:0002213 GO:0016042 ! positively regulates lipid catabolic process [Term] id: GO:0051017 name: actin filament bundle assembly alt_id: GO:0045011 def: "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:ai] synonym: "actin bundling activity" RELATED [] synonym: "actin cable assembly" RELATED [GOC:mah] synonym: "actin cable formation" RELATED [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061572 ! actin filament bundle organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0032432 ! results in assembly of actin filament bundle relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002588 GO:0032432 ! results in assembly of actin filament bundle [Term] id: GO:0051031 name: tRNA transport def: "The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050658 ! RNA transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:17843 ! has primary input transfer RNA relationship: RO:0004009 CHEBI:17843 ! has primary input transfer RNA [Term] id: GO:0051032 name: nucleic acid transmembrane transporter activity def: "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai] is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33696 ! has primary input nucleic acid relationship: part_of GO:0050657 ! nucleic acid transport relationship: RO:0004009 CHEBI:33696 ! has primary input nucleic acid [Term] id: GO:0051033 name: RNA transmembrane transporter activity def: "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: Reactome:R-HSA-203906 "Exportin complex translocates pre-miRNA to cytosol" is_a: GO:0051032 ! nucleic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: part_of GO:0050658 ! RNA transport relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid [Term] id: GO:0051034 name: tRNA transmembrane transporter activity def: "Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other." [GOC:ai] is_a: GO:0051033 ! RNA transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:17843 ! has primary input transfer RNA relationship: part_of GO:0051031 ! tRNA transport relationship: RO:0004009 CHEBI:17843 ! has primary input transfer RNA [Term] id: GO:0051046 name: regulation of secretion def: "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046903 ! regulates secretion relationship: RO:0002211 GO:0046903 ! regulates secretion [Term] id: GO:0051047 name: positive regulation of secretion def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "activation of secretion" NARROW [] synonym: "stimulation of secretion" NARROW [] synonym: "up regulation of secretion" EXACT [] synonym: "up-regulation of secretion" EXACT [] synonym: "upregulation of secretion" EXACT [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046903 ! positively regulates secretion relationship: RO:0002213 GO:0046903 ! positively regulates secretion [Term] id: GO:0051048 name: negative regulation of secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "down regulation of secretion" EXACT [] synonym: "down-regulation of secretion" EXACT [] synonym: "downregulation of secretion" EXACT [] synonym: "inhibition of secretion" NARROW [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046903 ! negatively regulates secretion relationship: RO:0002212 GO:0046903 ! negatively regulates secretion [Term] id: GO:0051049 name: regulation of transport def: "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_yeast is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006810 ! regulates transport relationship: RO:0002211 GO:0006810 ! regulates transport [Term] id: GO:0051050 name: positive regulation of transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of transport" NARROW [] synonym: "stimulation of transport" NARROW [] synonym: "up regulation of transport" EXACT [] synonym: "up-regulation of transport" EXACT [] synonym: "upregulation of transport" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006810 ! positively regulates transport relationship: RO:0002213 GO:0006810 ! positively regulates transport [Term] id: GO:0051051 name: negative regulation of transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of transport" EXACT [] synonym: "down-regulation of transport" EXACT [] synonym: "downregulation of transport" EXACT [] synonym: "inhibition of transport" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006810 ! negatively regulates transport relationship: RO:0002212 GO:0006810 ! negatively regulates transport [Term] id: GO:0051055 name: negative regulation of lipid biosynthetic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "down regulation of lipid biosynthetic process" EXACT [] synonym: "down-regulation of lipid biosynthetic process" EXACT [] synonym: "downregulation of lipid biosynthetic process" EXACT [] synonym: "inhibition of lipid biosynthetic process" NARROW [] synonym: "negative regulation of lipid anabolism" EXACT [] synonym: "negative regulation of lipid biosynthesis" EXACT [] synonym: "negative regulation of lipid formation" EXACT [] synonym: "negative regulation of lipid synthesis" EXACT [] synonym: "negative regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008610 ! negatively regulates lipid biosynthetic process relationship: RO:0002212 GO:0008610 ! negatively regulates lipid biosynthetic process [Term] id: GO:0051078 name: meiotic nuclear membrane disassembly def: "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." [GOC:bf] synonym: "meiotic nuclear envelope breakdown" RELATED [] synonym: "meiotic nuclear envelope catabolism" RELATED [] synonym: "meiotic nuclear envelope degradation" RELATED [] synonym: "meiotic nuclear envelope disassembly" RELATED [] is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0051080 name: meiosis II nuclear membrane disassembly def: "The controlled breakdown of the nuclear membranes during the second division of meiosis." [GOC:bf] synonym: "meiosis II nuclear envelope breakdown" RELATED [] synonym: "meiosis II nuclear envelope catabolism" RELATED [] synonym: "meiosis II nuclear envelope degradation" RELATED [] synonym: "meiosis II nuclear envelope disassembly" RELATED [] is_a: GO:0051078 ! meiotic nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0007135 ! meiosis II relationship: part_of GO:0007135 ! meiosis II [Term] id: GO:0051081 name: nuclear membrane disassembly def: "The controlled breakdown of the nuclear membranes, for example during cellular division." [GOC:ai] synonym: "nuclear envelope breakdown" RELATED [] synonym: "nuclear envelope catabolism" RELATED [] synonym: "nuclear envelope degradation" RELATED [] synonym: "nuclear envelope disassembly" RELATED [] is_a: GO:0030397 ! membrane disassembly is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0031965 ! results in disassembly of nuclear membrane relationship: RO:0002590 GO:0031965 ! results in disassembly of nuclear membrane [Term] id: GO:0051093 name: negative regulation of developmental process def: "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "down regulation of developmental process" EXACT [] synonym: "down-regulation of developmental process" EXACT [] synonym: "downregulation of developmental process" EXACT [] synonym: "inhibition of developmental process" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032502 ! negatively regulates developmental process relationship: RO:0002212 GO:0032502 ! negatively regulates developmental process [Term] id: GO:0051094 name: positive regulation of developmental process def: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "activation of developmental process" NARROW [] synonym: "stimulation of developmental process" NARROW [] synonym: "up regulation of developmental process" EXACT [] synonym: "up-regulation of developmental process" EXACT [] synonym: "upregulation of developmental process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032502 ! positively regulates developmental process relationship: RO:0002213 GO:0032502 ! positively regulates developmental process [Term] id: GO:0051119 name: sugar transmembrane transporter activity def: "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "sugar/polyol channel activity" NARROW [] xref: Reactome:R-HSA-428779 "GLUT7 and GLUT11 transport glucose and fructose" xref: Reactome:R-HSA-8875902 "SLC45A3 transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-8876319 "SLC50A1 transports Glc from cytosol to extracellular region" is_a: GO:0015144 ! carbohydrate transmembrane transporter activity [Term] id: GO:0051128 name: regulation of cellular component organization def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] subset: gocheck_do_not_annotate synonym: "regulation of cell organisation" RELATED [GOC:mah] synonym: "regulation of cell organization" RELATED [GOC:mah] synonym: "regulation of cellular component organisation" EXACT [] synonym: "regulation of cellular component organization and biogenesis" RELATED [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016043 ! regulates cellular component organization relationship: RO:0002211 GO:0016043 ! regulates cellular component organization [Term] id: GO:0051129 name: negative regulation of cellular component organization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "down regulation of cell organization" EXACT [] synonym: "down-regulation of cell organization" EXACT [] synonym: "downregulation of cell organization" EXACT [] synonym: "inhibition of cell organization" NARROW [] synonym: "negative regulation of cell organisation" RELATED [GOC:mah] synonym: "negative regulation of cellular component organization and biogenesis" RELATED [GOC:mah] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016043 ! negatively regulates cellular component organization relationship: RO:0002212 GO:0016043 ! negatively regulates cellular component organization [Term] id: GO:0051130 name: positive regulation of cellular component organization def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "activation of cell organization" NARROW [] synonym: "positive regulation of cell organisation" EXACT [] synonym: "positive regulation of cellular component organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cell organization" NARROW [] synonym: "up regulation of cell organization" EXACT [] synonym: "up-regulation of cell organization" EXACT [] synonym: "upregulation of cell organization" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016043 ! positively regulates cellular component organization relationship: RO:0002213 GO:0016043 ! positively regulates cellular component organization [Term] id: GO:0051145 name: smooth muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." [CL:0000192, GOC:ai] synonym: "nonstriated muscle cell differentiation" EXACT [] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000192 ! results in acquisition of features of smooth muscle cell relationship: RO:0002315 CL:0000192 ! results in acquisition of features of smooth muscle cell [Term] id: GO:0051146 name: striated muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." [CL:0000737, GOC:ai] synonym: "voluntary muscle cell differentiation" NARROW [] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000737 ! results in acquisition of features of striated muscle cell relationship: RO:0002315 CL:0000737 ! results in acquisition of features of striated muscle cell [Term] id: GO:0051147 name: regulation of muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042692 ! regulates muscle cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0042692 ! regulates muscle cell differentiation [Term] id: GO:0051148 name: negative regulation of muscle cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "down regulation of muscle cell differentiation" EXACT [] synonym: "down-regulation of muscle cell differentiation" EXACT [] synonym: "downregulation of muscle cell differentiation" EXACT [] synonym: "inhibition of muscle cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042692 ! negatively regulates muscle cell differentiation relationship: RO:0002212 GO:0042692 ! negatively regulates muscle cell differentiation [Term] id: GO:0051149 name: positive regulation of muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "activation of muscle cell differentiation" NARROW [] synonym: "stimulation of muscle cell differentiation" NARROW [] synonym: "up regulation of muscle cell differentiation" EXACT [] synonym: "up-regulation of muscle cell differentiation" EXACT [] synonym: "upregulation of muscle cell differentiation" EXACT [] xref: Reactome:R-HSA-525793 "Myogenesis" is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042692 ! positively regulates muscle cell differentiation relationship: RO:0002213 GO:0042692 ! positively regulates muscle cell differentiation [Term] id: GO:0051150 name: regulation of smooth muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051145 ! regulates smooth muscle cell differentiation relationship: RO:0002211 GO:0051145 ! regulates smooth muscle cell differentiation [Term] id: GO:0051151 name: negative regulation of smooth muscle cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "down regulation of smooth muscle cell differentiation" EXACT [] synonym: "down-regulation of smooth muscle cell differentiation" EXACT [] synonym: "downregulation of smooth muscle cell differentiation" EXACT [] synonym: "inhibition of smooth muscle cell differentiation" NARROW [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051145 ! negatively regulates smooth muscle cell differentiation relationship: RO:0002212 GO:0051145 ! negatively regulates smooth muscle cell differentiation [Term] id: GO:0051152 name: positive regulation of smooth muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "activation of smooth muscle cell differentiation" NARROW [] synonym: "stimulation of smooth muscle cell differentiation" NARROW [] synonym: "up regulation of smooth muscle cell differentiation" EXACT [] synonym: "up-regulation of smooth muscle cell differentiation" EXACT [] synonym: "upregulation of smooth muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051145 ! positively regulates smooth muscle cell differentiation relationship: RO:0002213 GO:0051145 ! positively regulates smooth muscle cell differentiation [Term] id: GO:0051153 name: regulation of striated muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051146 ! regulates striated muscle cell differentiation relationship: RO:0002211 GO:0051146 ! regulates striated muscle cell differentiation [Term] id: GO:0051154 name: negative regulation of striated muscle cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "down regulation of striated muscle cell differentiation" EXACT [] synonym: "down-regulation of striated muscle cell differentiation" EXACT [] synonym: "downregulation of striated muscle cell differentiation" EXACT [] synonym: "inhibition of striated muscle cell differentiation" NARROW [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051146 ! negatively regulates striated muscle cell differentiation relationship: RO:0002212 GO:0051146 ! negatively regulates striated muscle cell differentiation [Term] id: GO:0051155 name: positive regulation of striated muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "activation of striated muscle cell differentiation" NARROW [] synonym: "stimulation of striated muscle cell differentiation" NARROW [] synonym: "up regulation of striated muscle cell differentiation" EXACT [] synonym: "up-regulation of striated muscle cell differentiation" EXACT [] synonym: "upregulation of striated muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051146 ! positively regulates striated muscle cell differentiation relationship: RO:0002213 GO:0051146 ! positively regulates striated muscle cell differentiation [Term] id: GO:0051168 name: nuclear export def: "The directed movement of substances out of the nucleus." [GOC:ai] synonym: "export from nucleus" EXACT [] synonym: "nucleus export" EXACT [] synonym: "substance nuclear export" EXACT [] is_a: GO:0006913 ! nucleocytoplasmic transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0031981 ! has target start location nuclear lumen intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope relationship: RO:0002338 GO:0031981 ! has target start location nuclear lumen relationship: RO:0002339 GO:0005829 ! has target end location cytosol [Term] id: GO:0051169 name: nuclear transport def: "The directed movement of substances into, out of, or within the nucleus." [GOC:ai] subset: goslim_yeast synonym: "nucleus transport" EXACT [] xref: Wikipedia:Nuclear_transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002344 GO:0005634 ! results in transport to from or in nucleus relationship: RO:0002344 GO:0005634 ! results in transport to from or in nucleus [Term] id: GO:0051170 name: import into nucleus alt_id: GO:1902593 def: "The directed movement of substances into the nucleus." [GOC:ai] synonym: "nuclear import" EXACT [] synonym: "nuclear translocation" EXACT [] is_a: GO:0006913 ! nucleocytoplasmic transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0031981 ! has target end location nuclear lumen intersection_of: RO:0002342 GO:0005635 ! results in transport across nuclear envelope relationship: RO:0002338 GO:0005829 ! has target start location cytosol relationship: RO:0002339 GO:0031981 ! has target end location nuclear lumen created_by: jl creation_date: 2013-12-19T15:26:34Z [Term] id: GO:0051179 name: localization namespace: biological_process alt_id: GO:1902578 def: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "establishment and maintenance of cellular component location" NARROW [] synonym: "establishment and maintenance of localization" EXACT [] synonym: "establishment and maintenance of position" EXACT [] synonym: "establishment and maintenance of substance location" NARROW [] synonym: "establishment and maintenance of substrate location" NARROW [] synonym: "localisation" EXACT [GOC:mah] synonym: "single organism localization" RELATED [GOC:TermGenie] synonym: "single-organism localization" RELATED [] is_a: GO:0008150 ! biological process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27052" xsd:anyURI created_by: jl creation_date: 2013-12-18T13:51:04Z [Term] id: GO:0051216 name: cartilage development def: "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:cjm, PMID:23251424] synonym: "cartilage biogenesis" EXACT [] synonym: "cartilage biosynthesis" EXACT [] synonym: "cartilage element development" EXACT [] synonym: "cartilage formation" EXACT [] synonym: "cartilage organ development" EXACT [] synonym: "chondrogenesis" EXACT [] xref: Wikipedia:Chondrogenesis is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007844 ! results in development of cartilage element relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0001501 ! skeletal system development relationship: part_of GO:0061448 ! connective tissue development relationship: RO:0002296 UBERON:0007844 ! results in development of cartilage element [Term] id: GO:0051222 name: positive regulation of protein transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of protein transport" NARROW [] synonym: "stimulation of protein transport" NARROW [] synonym: "up regulation of protein transport" EXACT [] synonym: "up-regulation of protein transport" EXACT [] synonym: "upregulation of protein transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1904951 ! positive regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015031 ! positively regulates protein transport relationship: RO:0002213 GO:0015031 ! positively regulates protein transport [Term] id: GO:0051223 name: regulation of protein transport def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015031 ! regulates protein transport relationship: RO:0002211 GO:0015031 ! regulates protein transport [Term] id: GO:0051224 name: negative regulation of protein transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of protein transport" EXACT [] synonym: "down-regulation of protein transport" EXACT [] synonym: "downregulation of protein transport" EXACT [] synonym: "inhibition of protein transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1904950 ! negative regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015031 ! negatively regulates protein transport relationship: RO:0002212 GO:0015031 ! negatively regulates protein transport [Term] id: GO:0051234 name: establishment of localization namespace: biological_process def: "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos] subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "establishment of localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI [Term] id: GO:0051235 name: maintenance of location def: "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] synonym: "maintenance of localization" EXACT [] synonym: "retention" NARROW [] synonym: "sequestering" NARROW [] synonym: "storage" NARROW [] is_a: GO:0051179 ! localization [Term] id: GO:0051236 name: establishment of RNA localization def: "The directed movement of RNA to a specific location." [GOC:ai] synonym: "establishment of RNA localisation" EXACT [GOC:mah] synonym: "RNA positioning" EXACT [] synonym: "RNA recruitment" EXACT [] is_a: GO:0051234 ! establishment of localization relationship: part_of GO:0006403 ! RNA localization [Term] id: GO:0051239 name: regulation of multicellular organismal process def: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032501 ! regulates multicellular organismal process relationship: RO:0002211 GO:0032501 ! regulates multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0051240 name: positive regulation of multicellular organismal process def: "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "activation of multicellular organismal process" NARROW [] synonym: "stimulation of multicellular organismal process" NARROW [] synonym: "up regulation of multicellular organismal process" EXACT [] synonym: "up-regulation of multicellular organismal process" EXACT [] synonym: "upregulation of multicellular organismal process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032501 ! positively regulates multicellular organismal process relationship: RO:0002213 GO:0032501 ! positively regulates multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0051241 name: negative regulation of multicellular organismal process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "down regulation of multicellular organismal process" EXACT [] synonym: "down-regulation of multicellular organismal process" EXACT [] synonym: "downregulation of multicellular organismal process" EXACT [] synonym: "inhibition of multicellular organismal process" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032501 ! negatively regulates multicellular organismal process relationship: RO:0002212 GO:0032501 ! negatively regulates multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0051246 name: regulation of protein metabolic process alt_id: GO:0032268 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "regulation of cellular protein metabolic process" RELATED [] synonym: "regulation of cellular protein metabolism" RELATED [] synonym: "regulation of protein metabolism" EXACT [] is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019538 ! regulates protein metabolic process relationship: RO:0002211 GO:0019538 ! regulates protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051247 name: positive regulation of protein metabolic process alt_id: GO:0032270 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "activation of cellular protein metabolic process" NARROW [] synonym: "activation of protein metabolic process" NARROW [] synonym: "positive regulation of cellular protein metabolic process" EXACT [] synonym: "positive regulation of cellular protein metabolism" EXACT [] synonym: "positive regulation of protein metabolism" EXACT [] synonym: "stimulation of cellular protein metabolic process" NARROW [] synonym: "stimulation of protein metabolic process" NARROW [] synonym: "up regulation of cellular protein metabolic process" EXACT [] synonym: "up regulation of protein metabolic process" EXACT [] synonym: "up-regulation of cellular protein metabolic process" EXACT [] synonym: "up-regulation of protein metabolic process" EXACT [] synonym: "upregulation of cellular protein metabolic process" EXACT [] synonym: "upregulation of protein metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019538 ! positively regulates protein metabolic process relationship: RO:0002213 GO:0019538 ! positively regulates protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051248 name: negative regulation of protein metabolic process alt_id: GO:0032269 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." [GOC:ai] synonym: "down regulation of cellular protein metabolic process" EXACT [] synonym: "down regulation of protein metabolic process" EXACT [] synonym: "down-regulation of cellular protein metabolic process" EXACT [] synonym: "down-regulation of protein metabolic process" EXACT [] synonym: "downregulation of cellular protein metabolic process" EXACT [] synonym: "downregulation of protein metabolic process" EXACT [] synonym: "inhibition of cellular protein metabolic process" NARROW [] synonym: "inhibition of protein metabolic process" NARROW [] synonym: "negative regulation of cellular protein metabolic process" EXACT [] synonym: "negative regulation of cellular protein metabolism" EXACT [] synonym: "negative regulation of protein metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019538 ! negatively regulates protein metabolic process relationship: RO:0002212 GO:0019538 ! negatively regulates protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051249 name: regulation of lymphocyte activation def: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai] is_a: GO:0002694 ! regulation of leukocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0046649 ! regulates lymphocyte activation relationship: RO:0002211 GO:0046649 ! regulates lymphocyte activation [Term] id: GO:0051250 name: negative regulation of lymphocyte activation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "down regulation of lymphocyte activation" EXACT [] synonym: "down-regulation of lymphocyte activation" EXACT [] synonym: "downregulation of lymphocyte activation" EXACT [] synonym: "inhibition of lymphocyte activation" NARROW [] is_a: GO:0002695 ! negative regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0046649 ! negatively regulates lymphocyte activation relationship: RO:0002212 GO:0046649 ! negatively regulates lymphocyte activation [Term] id: GO:0051251 name: positive regulation of lymphocyte activation def: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "activation of lymphocyte activation" NARROW [] synonym: "stimulation of lymphocyte activation" NARROW [] synonym: "up regulation of lymphocyte activation" EXACT [] synonym: "up-regulation of lymphocyte activation" EXACT [] synonym: "upregulation of lymphocyte activation" EXACT [] is_a: GO:0002696 ! positive regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0046649 ! positively regulates lymphocyte activation relationship: RO:0002213 GO:0046649 ! positively regulates lymphocyte activation [Term] id: GO:0051252 name: regulation of RNA metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "regulation of RNA metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016070 ! regulates RNA metabolic process relationship: RO:0002211 GO:0016070 ! regulates RNA metabolic process [Term] id: GO:0051253 name: negative regulation of RNA metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] subset: gocheck_do_not_annotate synonym: "down regulation of RNA metabolic process" EXACT [] synonym: "down-regulation of RNA metabolic process" EXACT [] synonym: "downregulation of RNA metabolic process" EXACT [] synonym: "inhibition of RNA metabolic process" NARROW [] synonym: "negative regulation of RNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016070 ! negatively regulates RNA metabolic process relationship: RO:0002212 GO:0016070 ! negatively regulates RNA metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30771" xsd:anyURI [Term] id: GO:0051254 name: positive regulation of RNA metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "activation of RNA metabolic process" NARROW [] synonym: "positive regulation of RNA metabolism" EXACT [] synonym: "stimulation of RNA metabolic process" NARROW [] synonym: "up regulation of RNA metabolic process" EXACT [] synonym: "up-regulation of RNA metabolic process" EXACT [] synonym: "upregulation of RNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016070 ! positively regulates RNA metabolic process relationship: RO:0002213 GO:0016070 ! positively regulates RNA metabolic process [Term] id: GO:0051258 name: protein polymerization def: "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." [GOC:ai] subset: goslim_pir synonym: "protein polymer biosynthesis" EXACT [] synonym: "protein polymer biosynthetic process" EXACT [] synonym: "protein polymer formation" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly [Term] id: GO:0051261 name: protein depolymerization def: "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." [GOC:ai] subset: goslim_pir synonym: "protein polymer breakdown" EXACT [] synonym: "protein polymer catabolic process" EXACT [] synonym: "protein polymer catabolism" EXACT [] synonym: "protein polymer degradation" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0051276 name: chromosome organization alt_id: GO:0006323 alt_id: GO:0007001 alt_id: GO:0051277 def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl subset: goslim_drosophila subset: goslim_pir synonym: "chromosome organisation" EXACT [] synonym: "chromosome organization and biogenesis" RELATED [GOC:mah] synonym: "DNA condensation" EXACT [] synonym: "DNA packaging" NARROW [] synonym: "maintenance of genome integrity" RELATED [] synonym: "nuclear genome maintenance" RELATED [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005694 ! results in organization of chromosome relationship: RO:0002592 GO:0005694 ! results in organization of chromosome property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22811" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/4585" xsd:anyURI [Term] id: GO:0051301 name: cell division def: "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." [GOC:di, GOC:go_curators, GOC:pr] comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division. subset: goslim_chembl subset: goslim_drosophila subset: goslim_pir xref: Wikipedia:Cell_division is_a: GO:0009987 ! cellular process [Term] id: GO:0051302 name: regulation of cell division def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051301 ! regulates cell division relationship: RO:0002211 GO:0051301 ! regulates cell division [Term] id: GO:0051321 name: meiotic cell cycle alt_id: GO:0007126 def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." [GOC:ai] comment: Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. subset: goslim_drosophila subset: goslim_yeast synonym: "meiosis" RELATED [] xref: Wikipedia:Meiosis is_a: GO:0007049 ! cell cycle is_a: GO:0022414 ! reproductive process intersection_of: GO:0007049 ! cell cycle intersection_of: has_part GO:0140013 ! meiotic nuclear division relationship: has_part GO:0140013 ! meiotic nuclear division relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0019953 ! sexual reproduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24599" xsd:anyURI [Term] id: GO:0051338 name: regulation of transferase activity def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_obsoletion_candidate synonym: "transferase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016740 ! regulates transferase activity relationship: RO:0002211 GO:0016740 ! regulates transferase activity [Term] id: GO:0051402 name: neuron apoptotic process def: "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540, GOC:mtg_apoptosis] synonym: "apoptosis of neuronal cells" EXACT [] synonym: "apoptosis of neurons" EXACT [] synonym: "neuron apoptosis" NARROW [] synonym: "neuron programmed cell death by apoptosis" EXACT [] synonym: "neuronal cell apoptosis" EXACT [] synonym: "neuronal cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of neuronal cells by apoptosis" EXACT [] synonym: "programmed cell death of neurons by apoptosis" EXACT [] synonym: "programmed cell death, neuronal cells" EXACT [] synonym: "programmed cell death, neurons" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000540 ! occurs in neuron relationship: BFO:0000066 CL:0000540 ! occurs in neuron property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0051410 name: detoxification of nitrogen compound def: "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." [GOC:ai] synonym: "detoxification of nitrogenous compound" EXACT [] synonym: "nitric oxide (NO) detoxification" NARROW [] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity relationship: part_of GO:1901698 ! response to nitrogen compound relationship: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity [Term] id: GO:0051445 name: regulation of meiotic cell cycle def: "Any process that modulates the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "meiotic cell cycle modulation" EXACT [] synonym: "meiotic cell cycle regulation" EXACT [] synonym: "meiotic cell cycle regulator" RELATED [] synonym: "modulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051321 ! regulates meiotic cell cycle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0051321 ! regulates meiotic cell cycle [Term] id: GO:0051446 name: positive regulation of meiotic cell cycle def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "activation of progression through meiotic cell cycle" NARROW [] synonym: "positive regulation of meiotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through meiotic cell cycle" NARROW [] synonym: "up regulation of progression through meiotic cell cycle" EXACT [] synonym: "up-regulation of progression through meiotic cell cycle" EXACT [] synonym: "upregulation of progression through meiotic cell cycle" EXACT [] is_a: GO:0045787 ! positive regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051321 ! positively regulates meiotic cell cycle relationship: RO:0002213 GO:0051321 ! positively regulates meiotic cell cycle [Term] id: GO:0051447 name: negative regulation of meiotic cell cycle def: "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "down regulation of progression through meiotic cell cycle" EXACT [] synonym: "down-regulation of progression through meiotic cell cycle" EXACT [] synonym: "downregulation of progression through meiotic cell cycle" EXACT [] synonym: "inhibition of progression through meiotic cell cycle" NARROW [] synonym: "negative regulation of meiotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0045786 ! negative regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051321 ! negatively regulates meiotic cell cycle relationship: RO:0002212 GO:0051321 ! negatively regulates meiotic cell cycle [Term] id: GO:0051450 name: myoblast proliferation def: "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000056 ! acts on population of myoblast relationship: RO:0012003 CL:0000056 ! acts on population of myoblast property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0051451 name: myoblast migration def: "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000056 ! results in movement of myoblast relationship: RO:0002565 CL:0000056 ! results in movement of myoblast property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0051457 name: maintenance of protein location in nucleus def: "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus." [GOC:ai] synonym: "maintenance of nuclear protein localization" EXACT [] synonym: "maintenance of protein localization in nucleus" RELATED [GOC:dph, GOC:tb] synonym: "maintenance of protein location in cell nucleus" EXACT [] synonym: "nuclear protein retention" NARROW [] synonym: "nuclear protein sequestering" NARROW [] synonym: "nuclear protein sequestration" NARROW [] synonym: "protein retention in nucleus" NARROW [] synonym: "protein sequestration in nucleus" NARROW [] synonym: "protein storage in nucleus" NARROW [] synonym: "protein-nuclear retention" NARROW [] synonym: "sequestration of protein in nucleus" NARROW [] synonym: "storage of protein in nucleus" NARROW [] is_a: GO:0072595 ! maintenance of protein localization in organelle intersection_of: GO:0045185 ! maintenance of protein location intersection_of: BFO:0000066 GO:0005634 ! occurs in nucleus relationship: BFO:0000066 GO:0005634 ! occurs in nucleus relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0034504 ! protein localization to nucleus [Term] id: GO:0051469 name: vesicle fusion with vacuole alt_id: GO:0042146 def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." [GOC:ai] synonym: "heterotypic vacuole fusion (non-autophagic)" RELATED [] synonym: "heterotypic vacuole fusion, non-autophagic" RELATED [] is_a: GO:0006906 ! vesicle fusion is_a: GO:0097576 ! vacuole fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005773 ! results in fusion of vacuole intersection_of: RO:0012008 GO:0031982 ! results in fusion of vesicle relationship: RO:0012008 GO:0031982 ! results in fusion of vesicle [Term] id: GO:0051493 name: regulation of cytoskeleton organization def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007010 ! regulates cytoskeleton organization relationship: RO:0002211 GO:0007010 ! regulates cytoskeleton organization [Term] id: GO:0051494 name: negative regulation of cytoskeleton organization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "down regulation of cytoskeleton organization" EXACT [] synonym: "down-regulation of cytoskeleton organization" EXACT [] synonym: "downregulation of cytoskeleton organization" EXACT [] synonym: "inhibition of cytoskeleton organization" NARROW [] synonym: "negative regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "negative regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007010 ! negatively regulates cytoskeleton organization relationship: RO:0002212 GO:0007010 ! negatively regulates cytoskeleton organization [Term] id: GO:0051495 name: positive regulation of cytoskeleton organization def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "activation of cytoskeleton organization" NARROW [] synonym: "positive regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "positive regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cytoskeleton organization" NARROW [] synonym: "up regulation of cytoskeleton organization" EXACT [] synonym: "up-regulation of cytoskeleton organization" EXACT [] synonym: "upregulation of cytoskeleton organization" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007010 ! positively regulates cytoskeleton organization relationship: RO:0002213 GO:0007010 ! positively regulates cytoskeleton organization [Term] id: GO:0051588 name: regulation of neurotransmitter transport def: "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006836 ! regulates neurotransmitter transport relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0006836 ! regulates neurotransmitter transport [Term] id: GO:0051589 name: negative regulation of neurotransmitter transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of neurotransmitter transport" EXACT [] synonym: "down-regulation of neurotransmitter transport" EXACT [] synonym: "downregulation of neurotransmitter transport" EXACT [] synonym: "inhibition of neurotransmitter transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006836 ! negatively regulates neurotransmitter transport relationship: RO:0002212 GO:0006836 ! negatively regulates neurotransmitter transport [Term] id: GO:0051590 name: positive regulation of neurotransmitter transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of neurotransmitter transport" NARROW [] synonym: "stimulation of neurotransmitter transport" NARROW [] synonym: "up regulation of neurotransmitter transport" EXACT [] synonym: "up-regulation of neurotransmitter transport" EXACT [] synonym: "upregulation of neurotransmitter transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006836 ! positively regulates neurotransmitter transport relationship: RO:0002213 GO:0006836 ! positively regulates neurotransmitter transport [Term] id: GO:0051602 name: response to electrical stimulus def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus." [GOC:ai] synonym: "response to electricity" RELATED [] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0051606 name: detection of stimulus def: "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." [GOC:add, GOC:ai, GOC:dph, GOC:mah] subset: goslim_pir synonym: "perception of stimulus" RELATED [] synonym: "stimulus detection" EXACT [] synonym: "stimulus sensing" RELATED [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051620 name: norepinephrine uptake def: "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] synonym: "levarterenol reuptake" EXACT [] synonym: "levarterenol uptake" EXACT [] synonym: "noradrenaline reuptake" EXACT [] synonym: "noradrenaline uptake" EXACT [] synonym: "norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "norepinephrine reuptake" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0090493 ! catecholamine uptake intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) [Term] id: GO:0051621 name: regulation of norepinephrine uptake def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." [GOC:ai] synonym: "regulation of levarterenol uptake" EXACT [] synonym: "regulation of noradrenaline uptake" EXACT [] synonym: "regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051620 ! regulates norepinephrine uptake relationship: RO:0002211 GO:0051620 ! regulates norepinephrine uptake [Term] id: GO:0051622 name: negative regulation of norepinephrine uptake def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "down regulation of norepinephrine uptake" EXACT [] synonym: "down-regulation of norepinephrine uptake" EXACT [] synonym: "downregulation of norepinephrine uptake" EXACT [] synonym: "negative regulation of levarterenol uptake" EXACT [] synonym: "negative regulation of noradrenaline uptake" EXACT [] synonym: "negative regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051620 ! negatively regulates norepinephrine uptake relationship: RO:0002212 GO:0051620 ! negatively regulates norepinephrine uptake [Term] id: GO:0051623 name: positive regulation of norepinephrine uptake def: "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "activation of norepinephrine uptake" NARROW [] synonym: "positive regulation of levarterenol uptake" EXACT [] synonym: "positive regulation of noradrenaline uptake" EXACT [] synonym: "positive regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of norepinephrine uptake" NARROW [] synonym: "up regulation of norepinephrine uptake" EXACT [] synonym: "up-regulation of norepinephrine uptake" EXACT [] synonym: "upregulation of norepinephrine uptake" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051620 ! positively regulates norepinephrine uptake relationship: RO:0002213 GO:0051620 ! positively regulates norepinephrine uptake [Term] id: GO:0051630 name: acetylcholine uptake def: "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:ai] synonym: "acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0015870 ! acetylcholine transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure [Term] id: GO:0051631 name: regulation of acetylcholine uptake def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." [GOC:ai] synonym: "regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051630 ! regulates acetylcholine uptake relationship: RO:0002211 GO:0051630 ! regulates acetylcholine uptake [Term] id: GO:0051632 name: negative regulation of acetylcholine uptake def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "down regulation of acetylcholine uptake" EXACT [] synonym: "down-regulation of acetylcholine uptake" EXACT [] synonym: "downregulation of acetylcholine uptake" EXACT [] synonym: "negative regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051630 ! negatively regulates acetylcholine uptake relationship: RO:0002212 GO:0051630 ! negatively regulates acetylcholine uptake [Term] id: GO:0051633 name: positive regulation of acetylcholine uptake def: "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "activation of acetylcholine uptake" NARROW [] synonym: "positive regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of acetylcholine uptake" NARROW [] synonym: "up regulation of acetylcholine uptake" EXACT [] synonym: "up-regulation of acetylcholine uptake" EXACT [] synonym: "upregulation of acetylcholine uptake" EXACT [] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051630 ! positively regulates acetylcholine uptake relationship: RO:0002213 GO:0051630 ! positively regulates acetylcholine uptake [Term] id: GO:0051640 name: organelle localization def: "Any process in which an organelle is transported to, and/or maintained in, a specific location." [GOC:ai] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "establishment and maintenance of organelle localization" EXACT [] synonym: "organelle localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0043226 ! has primary input organelle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0004009 GO:0043226 ! has primary input organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0051641 name: cellular localization alt_id: GO:1902580 def: "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." [GOC:tb, GOC:vw] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "cellular localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of cellular localization" EXACT [] synonym: "establishment and maintenance of localization in cell or cell membrane" EXACT [] synonym: "intracellular localization" NARROW [] synonym: "localization within cell" NARROW [] synonym: "single organism cellular localization" EXACT [GOC:TermGenie] synonym: "single-organism cellular localization" RELATED [] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI created_by: jl creation_date: 2013-12-18T14:04:32Z [Term] id: GO:0051645 name: Golgi localization def: "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "establishment and maintenance of Golgi localization" EXACT [] synonym: "Golgi apparatus localization" EXACT [] synonym: "Golgi body localization" EXACT [] synonym: "Golgi localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005794 ! has primary input Golgi apparatus relationship: RO:0004009 GO:0005794 ! has primary input Golgi apparatus [Term] id: GO:0051647 name: nucleus localization def: "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "cell nucleus localization" EXACT [] synonym: "establishment and maintenance of nucleus localization" EXACT [] synonym: "localization of nucleus" EXACT [] synonym: "nucleus localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005634 ! has primary input nucleus relationship: RO:0004009 GO:0005634 ! has primary input nucleus [Term] id: GO:0051648 name: vesicle localization def: "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cytoplasmic vesicle localization" EXACT [] synonym: "establishment and maintenance of vesicle localization" EXACT [] synonym: "vesicle localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle relationship: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0051649 name: establishment of localization in cell def: "Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "establishment of cellular localization" RELATED [GOC:dph, GOC:tb] synonym: "establishment of intracellular localization" NARROW [] synonym: "establishment of localisation in cell" EXACT [GOC:mah] synonym: "establishment of localization within cell" NARROW [] synonym: "positioning within cell" NARROW [] is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: BFO:0000066 CL:0000000 ! occurs in cell relationship: BFO:0000066 CL:0000000 ! occurs in cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0051641 ! cellular localization [Term] id: GO:0051650 name: establishment of vesicle localization def: "The directed movement of a vesicle to a specific location." [GOC:ai] synonym: "establishment of vesicle localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0051651 name: maintenance of location in cell def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." [GOC:ai] synonym: "cellular retention" NARROW [] synonym: "cellular sequestering" NARROW [] synonym: "cellular storage" NARROW [] synonym: "intracellular retention" NARROW [] synonym: "intracellular sequestering" NARROW [] synonym: "intracellular storage" NARROW [] synonym: "maintenance of cellular localization" RELATED [GOC:dph, GOC:tb] synonym: "maintenance of intracellular localization" NARROW [] synonym: "maintenance of localization in cell" RELATED [GOC:dph, GOC:tb] synonym: "maintenance of localization within cell" NARROW [] synonym: "retention within cell" NARROW [] synonym: "sequestering within cell" NARROW [] synonym: "storage within cell" NARROW [] is_a: GO:0009987 ! cellular process is_a: GO:0051235 ! maintenance of location intersection_of: GO:0051235 ! maintenance of location intersection_of: BFO:0000066 CL:0000000 ! occurs in cell relationship: BFO:0000066 CL:0000000 ! occurs in cell relationship: part_of GO:0051641 ! cellular localization [Term] id: GO:0051655 name: maintenance of vesicle location def: "Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] synonym: "maintenance of vesicle localization" RELATED [GOC:dph, GOC:tb] is_a: GO:0051648 ! vesicle localization is_a: GO:0051657 ! maintenance of organelle location intersection_of: GO:0051651 ! maintenance of location in cell intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0051656 name: establishment of organelle localization def: "The directed movement of an organelle to a specific location." [GOC:ai] synonym: "establishment of organelle localisation" EXACT [GOC:mah] is_a: GO:0051234 ! establishment of localization is_a: GO:0051640 ! organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 GO:0043226 ! has primary input organelle [Term] id: GO:0051657 name: maintenance of organelle location def: "Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] synonym: "maintenance of organelle localization" RELATED [GOC:dph, GOC:tb] is_a: GO:0051651 ! maintenance of location in cell relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0051640 ! organelle localization [Term] id: GO:0051658 name: maintenance of nucleus location def: "Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] synonym: "maintenance of cell nucleus location" EXACT [] synonym: "maintenance of nucleus localization" RELATED [GOC:dph, GOC:tb] is_a: GO:0051647 ! nucleus localization is_a: GO:0051657 ! maintenance of organelle location intersection_of: GO:0051651 ! maintenance of location in cell intersection_of: RO:0004009 GO:0005634 ! has primary input nucleus [Term] id: GO:0051668 name: localization within membrane def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." [GOC:ai] synonym: "establishment and maintenance of localization in membrane" EXACT [] synonym: "establishment and maintenance of position in membrane" EXACT [] synonym: "localisation within membrane" EXACT [GOC:mah] synonym: "localization to membrane" EXACT [] synonym: "positioning within membrane" NARROW [] is_a: GO:0051641 ! cellular localization intersection_of: GO:0051179 ! localization intersection_of: RO:0002339 GO:0016020 ! has target end location membrane relationship: RO:0002339 GO:0016020 ! has target end location membrane [Term] id: GO:0051674 name: localization of cell def: "Any process in which a cell is transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cell localization" EXACT [] synonym: "establishment and maintenance of cell localization" EXACT [] synonym: "establishment and maintenance of localization of cell" EXACT [] synonym: "localisation of cell" EXACT [GOC:mah] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 CL:0000000 ! has primary input cell relationship: RO:0004009 CL:0000000 ! has primary input cell [Term] id: GO:0051683 name: establishment of Golgi localization def: "The directed movement of the Golgi to a specific location." [GOC:ai] synonym: "establishment of Golgi apparatus localization" EXACT [] synonym: "establishment of Golgi body localization" EXACT [] synonym: "establishment of Golgi localisation" EXACT [GOC:mah] is_a: GO:0051645 ! Golgi localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: RO:0004009 GO:0005794 ! has primary input Golgi apparatus [Term] id: GO:0051684 name: maintenance of Golgi location def: "Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] synonym: "maintenance of Golgi apparatus localization" EXACT [] synonym: "maintenance of Golgi body localization" EXACT [] synonym: "maintenance of Golgi localization" RELATED [GOC:dph, GOC:tb] is_a: GO:0051645 ! Golgi localization is_a: GO:0051657 ! maintenance of organelle location intersection_of: GO:0051651 ! maintenance of location in cell intersection_of: RO:0004009 GO:0005794 ! has primary input Golgi apparatus [Term] id: GO:0051707 name: response to other organism alt_id: GO:0009613 alt_id: GO:0042828 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." [GOC:ai] is_a: GO:0043207 ! response to external biotic stimulus is_a: GO:0044419 ! biological process involved in interspecies interaction between organisms intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 NCBITaxon_Union:0000030 ! has primary input relationship: RO:0004009 NCBITaxon_Union:0000030 ! has primary input property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0051716 name: cellular response to stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate xref: Reactome:R-HSA-8953897 "Cellular responses to stimuli" is_a: GO:0009987 ! cellular process is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051726 name: regulation of cell cycle alt_id: GO:0000074 alt_id: GO:0007050 alt_id: GO:0071156 alt_id: GO:0071157 alt_id: GO:0071158 alt_id: GO:0071850 def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_yeast synonym: "arrest of mitotic cell cycle progression" NARROW [GOC:mah] synonym: "cell cycle arrest" NARROW [] synonym: "cell cycle modulation" EXACT [] synonym: "cell cycle regulation" EXACT [] synonym: "cell cycle regulator" RELATED [] synonym: "control of cell cycle progression" EXACT [] synonym: "mitotic cell cycle arrest" NARROW [] synonym: "modulation of cell cycle progression" EXACT [] synonym: "negative regulation of cell cycle arrest" NARROW [] synonym: "positive regulation of cell cycle arrest" NARROW [] synonym: "regulation of cell cycle arrest" NARROW [] synonym: "regulation of cell cycle progression" EXACT [] synonym: "regulation of progression through cell cycle" EXACT [] synonym: "tumor suppressor" RELATED [] xref: Reactome:R-HSA-156711 "Polo-like kinase mediated events" xref: Reactome:R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007049 ! regulates cell cycle relationship: RO:0002211 GO:0007049 ! regulates cell cycle [Term] id: GO:0051781 name: positive regulation of cell division def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai] synonym: "activation of cell division" NARROW [] synonym: "stimulation of cell division" NARROW [] synonym: "up regulation of cell division" EXACT [] synonym: "up-regulation of cell division" EXACT [] synonym: "upregulation of cell division" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051301 ! positively regulates cell division relationship: RO:0002213 GO:0051301 ! positively regulates cell division [Term] id: GO:0051782 name: negative regulation of cell division def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." [GOC:ai] synonym: "down regulation of cell division" EXACT [] synonym: "down-regulation of cell division" EXACT [] synonym: "downregulation of cell division" EXACT [] synonym: "inhibition of cell division" NARROW [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051301 ! negatively regulates cell division relationship: RO:0002212 GO:0051301 ! negatively regulates cell division [Term] id: GO:0051783 name: regulation of nuclear division def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000280 ! regulates nuclear division relationship: RO:0002211 GO:0000280 ! regulates nuclear division [Term] id: GO:0051784 name: negative regulation of nuclear division def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "down regulation of nuclear division" EXACT [] synonym: "down-regulation of nuclear division" EXACT [] synonym: "downregulation of nuclear division" EXACT [] synonym: "inhibition of nuclear division" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0000280 ! negatively regulates nuclear division relationship: RO:0002212 GO:0000280 ! negatively regulates nuclear division [Term] id: GO:0051785 name: positive regulation of nuclear division def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "activation of nuclear division" NARROW [] synonym: "stimulation of nuclear division" NARROW [] synonym: "up regulation of nuclear division" EXACT [] synonym: "up-regulation of nuclear division" EXACT [] synonym: "upregulation of nuclear division" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000280 ! positively regulates nuclear division relationship: RO:0002213 GO:0000280 ! positively regulates nuclear division [Term] id: GO:0051875 name: pigment granule localization def: "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0048770 ! has primary input pigment granule relationship: part_of GO:0033059 ! cellular pigmentation relationship: RO:0004009 GO:0048770 ! has primary input pigment granule [Term] id: GO:0051890 name: regulation of cardioblast differentiation def: "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] is_a: GO:1905207 ! regulation of cardiocyte differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010002 ! regulates cardioblast differentiation relationship: RO:0002211 GO:0010002 ! regulates cardioblast differentiation [Term] id: GO:0051891 name: positive regulation of cardioblast differentiation def: "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "activation of cardioblast differentiation" NARROW [] synonym: "stimulation of cardioblast differentiation" NARROW [] synonym: "up regulation of cardioblast differentiation" EXACT [] synonym: "up-regulation of cardioblast differentiation" EXACT [] synonym: "upregulation of cardioblast differentiation" EXACT [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010002 ! positively regulates cardioblast differentiation relationship: RO:0002213 GO:0010002 ! positively regulates cardioblast differentiation [Term] id: GO:0051892 name: negative regulation of cardioblast differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "down regulation of cardioblast differentiation" EXACT [] synonym: "down-regulation of cardioblast differentiation" EXACT [] synonym: "downregulation of cardioblast differentiation" EXACT [] synonym: "inhibition of cardioblast differentiation" NARROW [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010002 ! negatively regulates cardioblast differentiation relationship: RO:0002212 GO:0010002 ! negatively regulates cardioblast differentiation [Term] id: GO:0051904 name: pigment granule transport def: "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "pigment granule translocation" EXACT [] is_a: GO:0006810 ! transport is_a: GO:0051875 ! pigment granule localization is_a: GO:0051905 ! establishment of pigment granule localization intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 GO:0048770 ! has primary input pigment granule [Term] id: GO:0051905 name: establishment of pigment granule localization def: "The directed movement of a pigment granule to a specific location." [GOC:ai] synonym: "establishment of pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051650 ! establishment of vesicle localization relationship: part_of GO:0051875 ! pigment granule localization [Term] id: GO:0051930 name: regulation of sensory perception of pain def: "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0051931 ! regulation of sensory perception intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019233 ! regulates sensory perception of pain relationship: RO:0002211 GO:0019233 ! regulates sensory perception of pain [Term] id: GO:0051931 name: regulation of sensory perception def: "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007600 ! regulates sensory perception relationship: RO:0002211 GO:0007600 ! regulates sensory perception [Term] id: GO:0051937 name: catecholamine transport def: "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, ISBN:0198506732] is_a: GO:0015844 ! monoamine transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0004009 CHEBI:33567 ! has primary input catecholamine [Term] id: GO:0051952 name: regulation of amine transport def: "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015837 ! regulates amine transport relationship: RO:0002211 GO:0015837 ! regulates amine transport [Term] id: GO:0051953 name: negative regulation of amine transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amine transport" EXACT [] synonym: "down-regulation of amine transport" EXACT [] synonym: "downregulation of amine transport" EXACT [] synonym: "inhibition of amine transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0015837 ! negatively regulates amine transport relationship: RO:0002212 GO:0015837 ! negatively regulates amine transport [Term] id: GO:0051954 name: positive regulation of amine transport def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of amine transport" NARROW [] synonym: "stimulation of amine transport" NARROW [] synonym: "up regulation of amine transport" EXACT [] synonym: "up-regulation of amine transport" EXACT [] synonym: "upregulation of amine transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015837 ! positively regulates amine transport relationship: RO:0002213 GO:0015837 ! positively regulates amine transport [Term] id: GO:0051955 name: regulation of amino acid transport def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006865 ! regulates amino acid transport relationship: RO:0002211 GO:0006865 ! regulates amino acid transport [Term] id: GO:0051956 name: negative regulation of amino acid transport def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amino acid transport" EXACT [] synonym: "down-regulation of amino acid transport" EXACT [] synonym: "downregulation of amino acid transport" EXACT [] synonym: "inhibition of amino acid transport" NARROW [] synonym: "negative regulation of amino acid transmembrane transport" EXACT [GOC:mah] is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006865 ! negatively regulates amino acid transport relationship: RO:0002212 GO:0006865 ! negatively regulates amino acid transport [Term] id: GO:0051957 name: positive regulation of amino acid transport def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of amino acid transport" NARROW [] synonym: "positive regulation of amino acid transmembrane transport" EXACT [GOC:mah] synonym: "stimulation of amino acid transport" NARROW [] synonym: "up regulation of amino acid transport" EXACT [] synonym: "up-regulation of amino acid transport" EXACT [] synonym: "upregulation of amino acid transport" EXACT [] is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006865 ! positively regulates amino acid transport relationship: RO:0002213 GO:0006865 ! positively regulates amino acid transport [Term] id: GO:0051960 name: regulation of nervous system development def: "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007399 ! regulates nervous system development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0007399 ! regulates nervous system development [Term] id: GO:0051961 name: negative regulation of nervous system development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "down regulation of nervous system development" EXACT [] synonym: "down-regulation of nervous system development" EXACT [] synonym: "downregulation of nervous system development" EXACT [] synonym: "inhibition of nervous system development" NARROW [] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007399 ! negatively regulates nervous system development relationship: RO:0002212 GO:0007399 ! negatively regulates nervous system development [Term] id: GO:0051962 name: positive regulation of nervous system development def: "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "activation of nervous system development" NARROW [] synonym: "stimulation of nervous system development" NARROW [] synonym: "up regulation of nervous system development" EXACT [] synonym: "up-regulation of nervous system development" EXACT [] synonym: "upregulation of nervous system development" EXACT [] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007399 ! positively regulates nervous system development relationship: RO:0002213 GO:0007399 ! positively regulates nervous system development [Term] id: GO:0051963 name: regulation of synapse assembly def: "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] subset: goslim_synapse synonym: "regulation of synapse biogenesis" EXACT [] synonym: "regulation of synaptogenesis" EXACT [] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007416 ! regulates synapse assembly relationship: RO:0002211 GO:0007416 ! regulates synapse assembly [Term] id: GO:0051964 name: negative regulation of synapse assembly def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "down regulation of synapse assembly" EXACT [] synonym: "down-regulation of synapse assembly" EXACT [] synonym: "downregulation of synapse assembly" EXACT [] synonym: "inhibition of synapse assembly" NARROW [] synonym: "negative regulation of synapse biogenesis" EXACT [] synonym: "negative regulation of synaptogenesis" EXACT [] is_a: GO:0051961 ! negative regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901889 ! negative regulation of cell junction assembly is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007416 ! negatively regulates synapse assembly relationship: RO:0002212 GO:0007416 ! negatively regulates synapse assembly [Term] id: GO:0051965 name: positive regulation of synapse assembly def: "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "activation of synapse assembly" NARROW [] synonym: "positive regulation of synapse biogenesis" EXACT [] synonym: "positive regulation of synaptogenesis" EXACT [] synonym: "stimulation of synapse assembly" NARROW [] synonym: "up regulation of synapse assembly" EXACT [] synonym: "up-regulation of synapse assembly" EXACT [] synonym: "upregulation of synapse assembly" EXACT [] is_a: GO:0051962 ! positive regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901890 ! positive regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007416 ! positively regulates synapse assembly relationship: RO:0002213 GO:0007416 ! positively regulates synapse assembly [Term] id: GO:0051969 name: regulation of transmission of nerve impulse def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019226 ! regulates transmission of nerve impulse relationship: RO:0002211 GO:0019226 ! regulates transmission of nerve impulse [Term] id: GO:0051970 name: negative regulation of transmission of nerve impulse def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "down regulation of transmission of nerve impulse" EXACT [] synonym: "down-regulation of transmission of nerve impulse" EXACT [] synonym: "downregulation of transmission of nerve impulse" EXACT [] synonym: "inhibition of transmission of nerve impulse" NARROW [] synonym: "negative regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019226 ! negatively regulates transmission of nerve impulse relationship: RO:0002212 GO:0019226 ! negatively regulates transmission of nerve impulse [Term] id: GO:0051971 name: positive regulation of transmission of nerve impulse def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "activation of transmission of nerve impulse" NARROW [] synonym: "positive regulation of conduction of nerve impulse" EXACT [GOC:dph] synonym: "stimulation of transmission of nerve impulse" NARROW [] synonym: "up regulation of transmission of nerve impulse" EXACT [] synonym: "up-regulation of transmission of nerve impulse" EXACT [] synonym: "upregulation of transmission of nerve impulse" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019226 ! positively regulates transmission of nerve impulse relationship: RO:0002213 GO:0019226 ! positively regulates transmission of nerve impulse [Term] id: GO:0051983 name: regulation of chromosome segregation def: "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007059 ! regulates chromosome segregation relationship: RO:0002211 GO:0007059 ! regulates chromosome segregation [Term] id: GO:0051984 name: positive regulation of chromosome segregation def: "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "activation of chromosome segregation" NARROW [] synonym: "stimulation of chromosome segregation" NARROW [] synonym: "up regulation of chromosome segregation" EXACT [] synonym: "up-regulation of chromosome segregation" EXACT [] synonym: "upregulation of chromosome segregation" EXACT [] is_a: GO:0051983 ! regulation of chromosome segregation is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007059 ! positively regulates chromosome segregation relationship: RO:0002213 GO:0007059 ! positively regulates chromosome segregation [Term] id: GO:0051985 name: negative regulation of chromosome segregation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "down regulation of chromosome segregation" EXACT [] synonym: "down-regulation of chromosome segregation" EXACT [] synonym: "downregulation of chromosome segregation" EXACT [] synonym: "inhibition of chromosome segregation" NARROW [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007059 ! negatively regulates chromosome segregation relationship: RO:0002212 GO:0007059 ! negatively regulates chromosome segregation [Term] id: GO:0055001 name: muscle cell development alt_id: GO:0048747 def: "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol] synonym: "muscle fiber development" EXACT [] synonym: "muscle fibre development" EXACT [] synonym: "myofiber development" EXACT [] synonym: "myofibre development" EXACT [] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000187 ! results in development of muscle cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042692 ! muscle cell differentiation relationship: RO:0002296 CL:0000187 ! results in development of muscle cell [Term] id: GO:0055002 name: striated muscle cell development def: "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000737 ! results in development of striated muscle cell relationship: part_of GO:0051146 ! striated muscle cell differentiation relationship: RO:0002296 CL:0000737 ! results in development of striated muscle cell [Term] id: GO:0055003 name: cardiac myofibril assembly def: "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol] synonym: "cardiac myofibril development" EXACT [] synonym: "cardiac myofibril morphogenesis" EXACT [] synonym: "heart myofibril assembly" RELATED [] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0097512 ! results in assembly of cardiac myofibril relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0055013 ! cardiac muscle cell development relationship: RO:0002588 GO:0097512 ! results in assembly of cardiac myofibril [Term] id: GO:0055006 name: cardiac cell development def: "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." [GOC:devbiol] synonym: "cardiocyte development" EXACT [GOC:dph] synonym: "heart cell development" RELATED [] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0002494 ! results in development of cardiocyte relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0035051 ! cardiocyte differentiation relationship: RO:0002296 CL:0002494 ! results in development of cardiocyte [Term] id: GO:0055007 name: cardiac muscle cell differentiation def: "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiomyocyte differentiation" EXACT [] synonym: "heart muscle cell differentiation" RELATED [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000746 ! results in acquisition of features of cardiac muscle cell relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: RO:0002315 CL:0000746 ! results in acquisition of features of cardiac muscle cell [Term] id: GO:0055008 name: cardiac muscle tissue morphogenesis def: "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." [GOC:devbiol] synonym: "heart muscle morphogenesis" EXACT [] synonym: "myocardium morphogenesis" BROAD [GOC:mtg_heart] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001133 ! results in morphogenesis of cardiac muscle tissue relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: RO:0002298 UBERON:0001133 ! results in morphogenesis of cardiac muscle tissue [Term] id: GO:0055009 name: atrial cardiac muscle tissue morphogenesis def: "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." [GOC:devbiol] synonym: "atrial heart muscle morphogenesis" EXACT [] synonym: "atrial myocardium morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac atrium muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004490 ! results in morphogenesis of cardiac muscle tissue of atrium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: part_of GO:0003228 ! atrial cardiac muscle tissue development relationship: RO:0002298 UBERON:0004490 ! results in morphogenesis of cardiac muscle tissue of atrium [Term] id: GO:0055010 name: ventricular cardiac muscle tissue morphogenesis def: "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." [GOC:devbiol] synonym: "cardiac ventricle muscle morphogenesis" EXACT [] synonym: "ventricular heart muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0018649 ! results in morphogenesis of cardiac muscle tissue of ventricle relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis relationship: part_of GO:0003229 ! ventricular cardiac muscle tissue development relationship: RO:0002298 UBERON:0018649 ! results in morphogenesis of cardiac muscle tissue of ventricle [Term] id: GO:0055013 name: cardiac muscle cell development alt_id: GO:0048739 def: "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiac muscle fiber development" EXACT [] synonym: "cardiac muscle fibre development" EXACT [] synonym: "cardiomyocyte cell development" EXACT [GOC:mtg_muscle] synonym: "heart muscle cell development" EXACT [] synonym: "heart muscle fiber development" RELATED [] is_a: GO:0055002 ! striated muscle cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000746 ! results in development of cardiac muscle cell relationship: part_of GO:0055007 ! cardiac muscle cell differentiation relationship: RO:0002296 CL:0000746 ! results in development of cardiac muscle cell [Term] id: GO:0055017 name: cardiac muscle tissue growth def: "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:devbiol] synonym: "heart muscle growth" EXACT [] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0001133 ! results in growth of cardiac muscle tissue relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: part_of GO:0060419 ! heart growth relationship: RO:0002343 UBERON:0001133 ! results in growth of cardiac muscle tissue [Term] id: GO:0055018 name: regulation of cardiac muscle fiber development def: "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "regulation of cardiac muscle fibre development" EXACT [] synonym: "regulation of heart muscle fiber development" EXACT [] is_a: GO:0060284 ! regulation of cell development is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055013 ! regulates cardiac muscle cell development relationship: RO:0002211 GO:0055013 ! regulates cardiac muscle cell development [Term] id: GO:0055019 name: negative regulation of cardiac muscle fiber development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "down regulation of cardiac muscle fiber development" EXACT [] synonym: "down-regulation of cardiac muscle fiber development" EXACT [] synonym: "downregulation of cardiac muscle fiber development" EXACT [] synonym: "inhibition of cardiac muscle fiber development" NARROW [] synonym: "negative regulation of cardiac muscle fibre development" EXACT [] synonym: "negative regulation of heart muscle fiber development" RELATED [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055018 ! regulation of cardiac muscle fiber development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055013 ! negatively regulates cardiac muscle cell development relationship: RO:0002212 GO:0055013 ! negatively regulates cardiac muscle cell development [Term] id: GO:0055020 name: positive regulation of cardiac muscle fiber development def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "activation of cardiac muscle fiber development" NARROW [] synonym: "positive regulation of cardiac muscle fibre development" EXACT [] synonym: "positive regulation of heart muscle fiber development" EXACT [] synonym: "stimulation of cardiac muscle fiber development" NARROW [] synonym: "up regulation of cardiac muscle fiber development" EXACT [] synonym: "up-regulation of cardiac muscle fiber development" EXACT [] synonym: "upregulation of cardiac muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0055018 ! regulation of cardiac muscle fiber development is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055013 ! positively regulates cardiac muscle cell development relationship: RO:0002213 GO:0055013 ! positively regulates cardiac muscle cell development [Term] id: GO:0055021 name: regulation of cardiac muscle tissue growth def: "Any process that modulates the frequency, rate or extent of cardiac muscle growth." [GOC:vk] is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055017 ! regulates cardiac muscle tissue growth relationship: RO:0002211 GO:0055017 ! regulates cardiac muscle tissue growth [Term] id: GO:0055022 name: negative regulation of cardiac muscle tissue growth def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "down regulation of cardiac muscle growth" EXACT [] synonym: "down-regulation of cardiac muscle growth" EXACT [] synonym: "downregulation of cardiac muscle growth" EXACT [] synonym: "inhibition of cardiac muscle growth" NARROW [] synonym: "negative regulation of heart muscle growth" RELATED [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0061117 ! negative regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055017 ! negatively regulates cardiac muscle tissue growth relationship: RO:0002212 GO:0055017 ! negatively regulates cardiac muscle tissue growth [Term] id: GO:0055023 name: positive regulation of cardiac muscle tissue growth def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "activation of cardiac muscle growth" NARROW [] synonym: "positive regulation of heart muscle growth" EXACT [] synonym: "stimulation of cardiac muscle growth" NARROW [] synonym: "up regulation of cardiac muscle growth" EXACT [] synonym: "up-regulation of cardiac muscle growth" EXACT [] synonym: "upregulation of cardiac muscle growth" EXACT [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0060421 ! positive regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055017 ! positively regulates cardiac muscle tissue growth relationship: RO:0002213 GO:0055017 ! positively regulates cardiac muscle tissue growth [Term] id: GO:0055024 name: regulation of cardiac muscle tissue development def: "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "regulation of heart muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048738 ! regulates cardiac muscle tissue development relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0048738 ! regulates cardiac muscle tissue development [Term] id: GO:0055025 name: positive regulation of cardiac muscle tissue development def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "activation of cardiac muscle development" NARROW [] synonym: "positive regulation of heart muscle development" EXACT [] synonym: "stimulation of cardiac muscle development" NARROW [] synonym: "up regulation of cardiac muscle development" EXACT [] synonym: "up-regulation of cardiac muscle development" EXACT [] synonym: "upregulation of cardiac muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048738 ! positively regulates cardiac muscle tissue development relationship: RO:0002213 GO:0048738 ! positively regulates cardiac muscle tissue development [Term] id: GO:0055026 name: negative regulation of cardiac muscle tissue development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "down regulation of cardiac muscle development" EXACT [] synonym: "down-regulation of cardiac muscle development" EXACT [] synonym: "downregulation of cardiac muscle development" EXACT [] synonym: "inhibition of cardiac muscle development" NARROW [] synonym: "negative regulation of heart muscle development" EXACT [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048738 ! negatively regulates cardiac muscle tissue development relationship: RO:0002212 GO:0048738 ! negatively regulates cardiac muscle tissue development [Term] id: GO:0055056 name: D-glucose transmembrane transporter activity alt_id: GO:0015579 def: "Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:jid, GOC:jsg, GOC:mah] xref: Reactome:R-HSA-429094 "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol" xref: Reactome:R-HSA-450095 "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region" xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2" xref: Reactome:R-HSA-5339524 "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-5632804 "SLC2A1 tetramer does not transport Glc from extracellular region to cytosol" xref: Reactome:R-HSA-5632871 "Defective SLC2A10 does not transport Glc from extracellular region to cytosol" xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen" xref: Reactome:R-HSA-8981553 "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-8981564 "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-8981570 "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-8981574 "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol" is_a: GO:0015149 ! hexose transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose relationship: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27326" xsd:anyURI [Term] id: GO:0055057 name: neuroblast division def: "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167] synonym: "neuroblast cell division" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007405 ! neuroblast proliferation relationship: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) [Term] id: GO:0055059 name: asymmetric neuroblast division def: "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0045165 ! cell fate commitment is_a: GO:0055057 ! neuroblast division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000031 ! has primary input neuroblast (sensu Vertebrata) [Term] id: GO:0055063 name: sulfate ion homeostasis alt_id: GO:0080174 def: "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell." [GOC:jid, GOC:mah] synonym: "sulfate homeostasis" EXACT [] synonym: "sulphate ion homeostasis" EXACT [] is_a: GO:0098771 ! inorganic ion homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:16189 ! regulates levels of sulfate relationship: RO:0002332 CHEBI:16189 ! regulates levels of sulfate [Term] id: GO:0055078 name: sodium ion homeostasis def: "Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] is_a: GO:0055080 ! monoatomic cation homeostasis is_a: GO:0098771 ! inorganic ion homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:29101 ! regulates levels of sodium(1+) relationship: RO:0002332 CHEBI:29101 ! regulates levels of sodium(1+) [Term] id: GO:0055080 name: monoatomic cation homeostasis def: "Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." [GOC:ceb, GOC:jid, GOC:mah] synonym: "cation homeostasis" BROAD [] is_a: GO:0050801 ! monoatomic ion homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:23906 ! regulates levels of monoatomic cation relationship: RO:0002332 CHEBI:23906 ! regulates levels of monoatomic cation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] id: GO:0055082 name: intracellular chemical homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell." [GOC:isa_complete, GOC:jid] synonym: "cellular chemical homeostasis" EXACT [] is_a: GO:0019725 ! cellular homeostasis is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: RO:0002332 CHEBI:24431 ! regulates levels of chemical entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24514" xsd:anyURI [Term] id: GO:0055085 name: transmembrane transport alt_id: GO:0090662 def: "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:dph, GOC:jid] comment: Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes. subset: goslim_chembl subset: goslim_drosophila subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_pombe subset: goslim_yeast synonym: "ATP hydrolysis coupled transmembrane transport" NARROW [] synonym: "membrane transport" EXACT [] xref: Reactome:R-HSA-382556 "ABC-family proteins mediated transport" xref: Reactome:R-HSA-425407 "SLC-mediated transmembrane transport" xref: Reactome:R-HSA-5223345 "Miscellaneous transport and binding events" is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane relationship: RO:0002342 GO:0016020 ! results in transport across membrane created_by: tb creation_date: 2015-10-21T13:22:47Z [Term] id: GO:0055086 name: nucleobase-containing small molecule metabolic process def: "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw] subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote subset: goslim_yeast synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT [] xref: Reactome:R-HSA-15869 "Metabolism of nucleotides" xref: Reactome:R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0044281 ! small molecule metabolic process [Term] id: GO:0055088 name: lipid homeostasis def: "Any process involved in the maintenance of an internal steady state of lipid within an organism or cell." [GOC:BHF, GOC:rl] is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:18059 ! regulates levels of lipid relationship: RO:0002332 CHEBI:18059 ! regulates levels of lipid [Term] id: GO:0055107 name: Golgi to secretory granule transport def: "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." [GOC:curators] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0030141 ! has target end location secretory granule relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus relationship: RO:0002339 GO:0030141 ! has target end location secretory granule [Term] id: GO:0055108 name: Golgi to transport vesicle transport def: "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002338 GO:0005794 ! has target start location Golgi apparatus intersection_of: RO:0002339 GO:0030133 ! has target end location transport vesicle relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: RO:0002338 GO:0005794 ! has target start location Golgi apparatus relationship: RO:0002339 GO:0030133 ! has target end location transport vesicle [Term] id: GO:0055111 name: ingression involved in gastrulation with mouth forming second def: "The migration of individual cells into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437] is_a: GO:0042074 ! cell migration involved in gastrulation intersection_of: GO:0001667 ! ameboidal-type cell migration intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second relationship: in_taxon NCBITaxon:33511 ! Deuterostomia relationship: part_of GO:0001702 ! gastrulation with mouth forming second [Term] id: GO:0055117 name: regulation of cardiac muscle contraction def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060048 ! regulates cardiac muscle contraction relationship: RO:0002211 GO:0060048 ! regulates cardiac muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0055118 name: negative regulation of cardiac muscle contraction def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0045822 ! negative regulation of heart contraction is_a: GO:0045988 ! negative regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060048 ! negatively regulates cardiac muscle contraction relationship: RO:0002212 GO:0060048 ! negatively regulates cardiac muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0055123 name: digestive system development def: "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jid] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001007 ! results in development of digestive system relationship: RO:0002296 UBERON:0001007 ! results in development of digestive system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0055127 name: vibrational conductance of sound to the inner ear def: "The transmission of vibrations via ossicles to the inner ear." [GOC:mh] is_a: GO:0032501 ! multicellular organismal process relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007605 ! sensory perception of sound created_by: jid creation_date: 2009-10-13T10:59:39Z [Term] id: GO:0060004 name: reflex namespace: biological_process def: "An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness." [GOC:dph, ISBN:0877797099] xref: Wikipedia:Reflex is_a: GO:0009605 ! response to external stimulus [Term] id: GO:0060008 name: Sertoli cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000216 ! results in acquisition of features of Sertoli cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0008584 ! male gonad development relationship: RO:0002315 CL:0000216 ! results in acquisition of features of Sertoli cell [Term] id: GO:0060009 name: Sertoli cell development def: "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." [GOC:dph] is_a: GO:0002064 ! epithelial cell development is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000216 ! results in development of Sertoli cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0060008 ! Sertoli cell differentiation relationship: RO:0002296 CL:0000216 ! results in development of Sertoli cell [Term] id: GO:0060011 name: Sertoli cell proliferation def: "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000216 ! acts on population of Sertoli cell relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0008584 ! male gonad development relationship: RO:0012003 CL:0000216 ! acts on population of Sertoli cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0060021 name: roof of mouth development def: "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities." [GOC:dph, ISBN:0721662544] synonym: "palatum development" EXACT [ISBN:0721662544] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0007375 ! results in development of roof of mouth relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0007375 ! results in development of roof of mouth [Term] id: GO:0060022 name: hard palate development def: "The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes." [GOC:dph, ISBN:0721662544] synonym: "palatum durum development" EXACT [ISBN:0721662544] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003216 ! results in development of hard palate relationship: in_taxon NCBITaxon:32524 ! Amniota relationship: part_of GO:0062009 ! secondary palate development relationship: RO:0002296 UBERON:0003216 ! results in development of hard palate [Term] id: GO:0060037 name: pharyngeal system development def: "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0008814 ! results in development of pharyngeal arch system relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0043009 ! chordate embryonic development relationship: RO:0002296 UBERON:0008814 ! results in development of pharyngeal arch system [Term] id: GO:0060038 name: cardiac muscle cell proliferation def: "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rph, PMID:11161571] synonym: "cardiac myocyte proliferation" EXACT [] synonym: "cardiomyocyte proliferation" RELATED [GOC:dph, PMID:10074473] synonym: "heart muscle cell proliferation" EXACT [] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000746 ! acts on population of cardiac muscle cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0055017 ! cardiac muscle tissue growth relationship: RO:0012003 CL:0000746 ! acts on population of cardiac muscle cell [Term] id: GO:0060039 name: pericardium development def: "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." [GOC:dph, GOC:rph, PMID:15138308, PMID:16376438] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002407 ! results in development of pericardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007507 ! heart development relationship: RO:0002296 UBERON:0002407 ! results in development of pericardium [Term] id: GO:0060041 name: retina development in camera-type eye alt_id: GO:0002073 def: "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:bf, GOC:dph, ISBN:0815340729] synonym: "retina development in camera-style eye" EXACT [] synonym: "retinal development" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: part_of GO:0043010 ! camera-type eye development intersection_of: RO:0002296 UBERON:0000966 ! results in development of retina relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0043010 ! camera-type eye development relationship: RO:0002296 UBERON:0000966 ! results in development of retina [Term] id: GO:0060042 name: retina morphogenesis in camera-type eye def: "The process in which the anatomical structure of the retina is generated and organized." [GOC:bf, GOC:dph, GOC:mtg_sensu] synonym: "retina morphogenesis in camera-style eye" EXACT [] synonym: "retinogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000966 ! results in morphogenesis of retina relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: RO:0002298 UBERON:0000966 ! results in morphogenesis of retina [Term] id: GO:0060043 name: regulation of cardiac muscle cell proliferation def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "regulation of cardiomyocyte proliferation" RELATED [GOC:dph] synonym: "regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060038 ! regulates cardiac muscle cell proliferation relationship: RO:0002211 GO:0060038 ! regulates cardiac muscle cell proliferation [Term] id: GO:0060044 name: negative regulation of cardiac muscle cell proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "negative regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060038 ! negatively regulates cardiac muscle cell proliferation relationship: RO:0002212 GO:0060038 ! negatively regulates cardiac muscle cell proliferation [Term] id: GO:0060045 name: positive regulation of cardiac muscle cell proliferation def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "positive regulation of heart muscle cell proliferation" RELATED [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060038 ! positively regulates cardiac muscle cell proliferation relationship: RO:0002213 GO:0060038 ! positively regulates cardiac muscle cell proliferation [Term] id: GO:0060047 name: heart contraction def: "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph] synonym: "cardiac contraction" RELATED [] synonym: "heart beating" EXACT [] synonym: "hemolymph circulation" RELATED [] is_a: GO:0003015 ! heart process relationship: part_of GO:0008015 ! blood circulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060048 name: cardiac muscle contraction def: "Muscle contraction of cardiac muscle tissue." [GOC:dph] synonym: "heart muscle contraction" EXACT [] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue relationship: BFO:0000066 UBERON:0001133 ! occurs in cardiac muscle tissue relationship: part_of GO:0060047 ! heart contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060065 name: uterus development def: "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] synonym: "Mullerian tract development" RELATED [] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000995 ! results in development of uterus relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002296 UBERON:0000995 ! results in development of uterus [Term] id: GO:0060066 name: oviduct development def: "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, PMID:22918811, PMID:27875265] synonym: "fallopian tube development" NARROW [GOC:bf] synonym: "Mullerian tract development" RELATED [] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003889 ! results in development of fallopian tube relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: RO:0002296 UBERON:0003889 ! results in development of fallopian tube [Term] id: GO:0060067 name: cervix development def: "The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] synonym: "Mullerian tract development" RELATED [] is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000002 ! results in development of uterine cervix relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002296 UBERON:0000002 ! results in development of uterine cervix [Term] id: GO:0060068 name: vagina development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] is_a: GO:0030540 ! female genitalia development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000996 ! results in development of vagina relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0000996 ! results in development of vagina [Term] id: GO:0060073 name: micturition def: "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." [GOC:dph] synonym: "urination" EXACT [] synonym: "urine voiding" EXACT [] xref: Wikipedia:Urination is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060083 name: smooth muscle contraction involved in micturition def: "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." [GOC:dph, PMID:15827347] synonym: "smooth muscle contraction involved in urination" RELATED [] synonym: "urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:dph] is_a: GO:0014832 ! urinary bladder smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: part_of GO:0060073 ! micturition relationship: part_of GO:0060073 ! micturition property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0060084 name: synaptic transmission involved in micturition def: "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347] synonym: "synaptic transmission involved in urination" RELATED [] is_a: GO:0007274 ! neuromuscular synaptic transmission intersection_of: GO:0007268 ! chemical synaptic transmission intersection_of: part_of GO:0060073 ! micturition relationship: part_of GO:0060073 ! micturition [Term] id: GO:0060096 name: serotonin secretion, neurotransmission def: "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." [GOC:dph] synonym: "serotonin release, neurotransmission" RELATED [GOC:tb] is_a: GO:0001820 ! serotonin secretion is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) [Term] id: GO:0060135 name: maternal process involved in female pregnancy def: "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0007565 ! female pregnancy [Term] id: GO:0060136 name: embryonic process involved in female pregnancy def: "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: part_of GO:0007565 ! female pregnancy intersection_of: part_of GO:0009790 ! embryo development relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0007565 ! female pregnancy relationship: part_of GO:0009792 ! embryo development ending in birth or egg hatching [Term] id: GO:0060142 name: regulation of syncytium formation by plasma membrane fusion def: "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000768 ! regulates syncytium formation by plasma membrane fusion relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0000768 ! regulates syncytium formation by plasma membrane fusion [Term] id: GO:0060143 name: positive regulation of syncytium formation by plasma membrane fusion def: "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000768 ! positively regulates syncytium formation by plasma membrane fusion relationship: RO:0002213 GO:0000768 ! positively regulates syncytium formation by plasma membrane fusion [Term] id: GO:0060156 name: milk ejection reflex namespace: biological_process def: "A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness." [GOC:cjm, GOC:dph, GOC:mr, GOC:st] synonym: "milk ejection" EXACT [] is_a: GO:0007589 ! body fluid secretion is_a: GO:0032941 ! secretion by tissue is_a: GO:0060004 ! reflex relationship: part_of GO:0007595 ! lactation [Term] id: GO:0060157 name: urinary bladder development def: "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." [GOC:dph, GOC:ln, GOC:mr, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001255 ! results in development of urinary bladder relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0072001 ! renal system development relationship: RO:0002296 UBERON:0001255 ! results in development of urinary bladder property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0060166 name: olfactory pit development def: "The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx." [GOC:dph, ISBN:0124020607] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005870 ! results in development of olfactory pit relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0043584 ! nose development relationship: RO:0002296 UBERON:0005870 ! results in development of olfactory pit property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22589" xsd:anyURI [Term] id: GO:0060170 name: ciliary membrane alt_id: GO:0020017 def: "The portion of the plasma membrane surrounding a cilium." [GOC:cilia, GOC:dph, GOC:rph] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. synonym: "cilial membrane" EXACT [] synonym: "cilium membrane" EXACT [] synonym: "flagellar membrane" NARROW [] synonym: "flagellum membrane" NARROW [] is_a: GO:0031253 ! cell projection membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005929 ! cilium relationship: bounding_layer_of GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005929 ! cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060173 name: limb development def: "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." [GOC:dgh, GOC:dph, PMID:11487378] synonym: "limb bud development" NARROW [GOC:dph] synonym: "paired limb/fin development" EXACT [] xref: Wikipedia:Limb_development is_a: GO:0048736 ! appendage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004708 ! results in development of paired limb/fin relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0004708 ! results in development of paired limb/fin [Term] id: GO:0060174 name: limb bud formation def: "The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable." [GOC:dgh, GOC:dph] synonym: "limb formation" EXACT [] synonym: "limbbud formation" EXACT [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002101 ! results in formation of anatomical entity limb relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0035108 ! limb morphogenesis relationship: RO:0002297 UBERON:0002101 ! results in formation of anatomical entity limb [Term] id: GO:0060214 name: endocardium formation def: "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:bf, GOC:dph, PMID:17722983] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002165 ! results in formation of anatomical entity endocardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003160 ! endocardium morphogenesis relationship: RO:0002297 UBERON:0002165 ! results in formation of anatomical entity endocardium [Term] id: GO:0060218 name: hematopoietic stem cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:bf, GOC:BHF, GOC:dph, GOC:rl, PMID:15378083] synonym: "haematopoietic stem cell differentiation" EXACT [] synonym: "haemopoietic stem cell differentiation" EXACT [] synonym: "hemopoietic stem cell differentiation" EXACT [] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000037 ! results in acquisition of features of hematopoietic stem cell relationship: RO:0002315 CL:0000037 ! results in acquisition of features of hematopoietic stem cell [Term] id: GO:0060219 name: camera-type eye photoreceptor cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010009 ! results in acquisition of features of camera-type eye photoreceptor cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003407 ! neural retina development relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye relationship: RO:0002315 CL:0010009 ! results in acquisition of features of camera-type eye photoreceptor cell [Term] id: GO:0060221 name: retinal rod cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." [GOC:dph] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000604 ! results in acquisition of features of retinal rod cell relationship: RO:0002315 CL:0000604 ! results in acquisition of features of retinal rod cell [Term] id: GO:0060231 name: mesenchymal to epithelial transition def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "epithelial cell differentiation from mesenchymal cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] synonym: "mesenchymal-epithelial transition" EXACT [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000066 ! results in acquisition of features of epithelial cell intersection_of: RO:0004009 CL:0008019 ! has primary input mesenchymal cell relationship: RO:0004009 CL:0008019 ! has primary input mesenchymal cell [Term] id: GO:0060251 name: regulation of glial cell proliferation def: "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014009 ! regulates glial cell proliferation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0014009 ! regulates glial cell proliferation [Term] id: GO:0060252 name: positive regulation of glial cell proliferation def: "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014009 ! positively regulates glial cell proliferation relationship: RO:0002213 GO:0014009 ! positively regulates glial cell proliferation [Term] id: GO:0060253 name: negative regulation of glial cell proliferation def: "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014009 ! negatively regulates glial cell proliferation relationship: RO:0002212 GO:0014009 ! negatively regulates glial cell proliferation [Term] id: GO:0060255 name: regulation of macromolecule metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043170 ! regulates macromolecule metabolic process relationship: RO:0002211 GO:0043170 ! regulates macromolecule metabolic process [Term] id: GO:0060271 name: cilium assembly alt_id: GO:0042384 def: "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:BHF, GOC:cilia, GOC:dph, GOC:kmv, GOC:pr, GOC:vw, ISBN:0198506732, PMID:13978319, PMID:27350441] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "ciliogenesis" EXACT [] synonym: "cilium biogenesis" RELATED [GOC:mah] synonym: "cilium formation" EXACT [] synonym: "cilium morphogenesis" RELATED [] synonym: "cilium organization" RELATED [GOC:dph] synonym: "microtubule-based flagellum assembly" EXACT [] xref: Reactome:R-HSA-5617833 "Cilium Assembly" is_a: GO:0044782 ! cilium organization is_a: GO:0070925 ! organelle assembly is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005929 ! results in assembly of cilium relationship: has_part GO:0035082 ! axoneme assembly relationship: has_part GO:0035735 ! intraciliary transport involved in cilium assembly relationship: has_part GO:0061512 ! protein localization to cilium relationship: has_part GO:0097712 ! vesicle targeting, trans-Golgi to periciliary membrane compartment relationship: has_part GO:1905349 ! ciliary transition zone assembly relationship: RO:0002588 GO:0005929 ! results in assembly of cilium relationship: starts_with GO:0097711 ! ciliary basal body-plasma membrane docking property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060281 name: regulation of oocyte development def: "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb, PMID:2394318] is_a: GO:1905879 ! regulation of oogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048599 ! regulates oocyte development relationship: RO:0002211 GO:0048599 ! regulates oocyte development [Term] id: GO:0060282 name: positive regulation of oocyte development def: "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048599 ! positively regulates oocyte development relationship: RO:0002213 GO:0048599 ! positively regulates oocyte development [Term] id: GO:0060283 name: negative regulation of oocyte development def: "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048599 ! negatively regulates oocyte development relationship: RO:0002212 GO:0048599 ! negatively regulates oocyte development [Term] id: GO:0060284 name: regulation of cell development def: "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048468 ! regulates cell development relationship: RO:0002211 GO:0048468 ! regulates cell development [Term] id: GO:0060285 name: cilium-dependent cell motility alt_id: GO:0071974 def: "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, GOC:mtg_cambridge_2013] comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent. synonym: "ciliary cell motility" RELATED [] synonym: "cilium cell motility" EXACT [] synonym: "microtubule-based flagellar cell motility" EXACT [] is_a: GO:0001539 ! cilium or flagellum-dependent cell motility relationship: has_part GO:0003341 ! cilium movement relationship: in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060294 name: cilium movement involved in cell motility def: "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003341 ! cilium movement intersection_of: GO:0003341 ! cilium movement intersection_of: part_of GO:0048870 ! cell motility relationship: part_of GO:0060285 ! cilium-dependent cell motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060295 name: regulation of cilium movement involved in cell motility def: "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:1902019 ! regulation of cilium-dependent cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060294 ! regulates cilium movement involved in cell motility relationship: RO:0002211 GO:0060294 ! regulates cilium movement involved in cell motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:451864 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060297 name: regulation of sarcomere organization def: "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045214 ! regulates sarcomere organization relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0045214 ! regulates sarcomere organization [Term] id: GO:0060298 name: positive regulation of sarcomere organization def: "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045214 ! positively regulates sarcomere organization relationship: RO:0002213 GO:0045214 ! positively regulates sarcomere organization [Term] id: GO:0060299 name: negative regulation of sarcomere organization def: "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "negative regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045214 ! negatively regulates sarcomere organization relationship: RO:0002212 GO:0045214 ! negatively regulates sarcomere organization [Term] id: GO:0060322 name: head development def: "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000033 ! results in development of head relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0000033 ! results in development of head [Term] id: GO:0060323 name: head morphogenesis def: "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000033 ! results in morphogenesis of head relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0010171 ! body morphogenesis relationship: part_of GO:0060322 ! head development relationship: RO:0002298 UBERON:0000033 ! results in morphogenesis of head [Term] id: GO:0060324 name: face development def: "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001456 ! results in development of face relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0060322 ! head development relationship: RO:0002296 UBERON:0001456 ! results in development of face [Term] id: GO:0060325 name: face morphogenesis def: "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001456 ! results in morphogenesis of face relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0060323 ! head morphogenesis relationship: part_of GO:0060324 ! face development relationship: RO:0002298 UBERON:0001456 ! results in morphogenesis of face [Term] id: GO:0060341 name: regulation of cellular localization def: "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb] synonym: "regulation of cellular localisation" EXACT [GOC:mah] is_a: GO:0032879 ! regulation of localization is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051641 ! regulates cellular localization relationship: RO:0002211 GO:0051641 ! regulates cellular localization [Term] id: GO:0060343 name: trabecula formation def: "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] synonym: "trabecula biogenesis" RELATED [GOC:dph] synonym: "trabeculation" EXACT [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000440 ! results in formation of anatomical entity trabecula relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: part_of GO:0061383 ! trabecula morphogenesis relationship: RO:0002297 UBERON:0000440 ! results in formation of anatomical entity trabecula [Term] id: GO:0060344 name: liver trabecula formation def: "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "liver trabecula biogenesis" RELATED [] synonym: "liver trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0010183 ! results in formation of anatomical entity liver trabecula relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001889 ! liver development relationship: RO:0002297 UBERON:0010183 ! results in formation of anatomical entity liver trabecula [Term] id: GO:0060345 name: spleen trabecula formation def: "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "spleen trabecula biogenesis" RELATED [GOC:dph] synonym: "spleen trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001265 ! results in formation of anatomical entity trabecula of spleen relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0048536 ! spleen development relationship: RO:0002297 UBERON:0001265 ! results in formation of anatomical entity trabecula of spleen [Term] id: GO:0060347 name: heart trabecula formation def: "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "cardiac trabecula formation" EXACT [GOC:dph] synonym: "cardiac trabeculation" EXACT [GOC:dph] synonym: "heart trabecula biogenesis" RELATED [GOC:dph] synonym: "heart trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002511 ! results in formation of anatomical entity trabecula carnea relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: part_of GO:0061384 ! heart trabecula morphogenesis relationship: RO:0002297 UBERON:0002511 ! results in formation of anatomical entity trabecula carnea [Term] id: GO:0060348 name: bone development def: "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048513 ! animal organ development intersection_of: RO:0002296 UBERON:0001474 ! results in development of bone element relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001501 ! skeletal system development relationship: RO:0002296 UBERON:0001474 ! results in development of bone element [Term] id: GO:0060349 name: bone morphogenesis def: "The process in which bones are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001474 ! results in morphogenesis of bone element relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048705 ! skeletal system morphogenesis relationship: part_of GO:0060348 ! bone development relationship: RO:0002298 UBERON:0001474 ! results in morphogenesis of bone element [Term] id: GO:0060350 name: endochondral bone morphogenesis def: "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." [GOC:dph, PMID:11680679] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0002513 ! results in morphogenesis of endochondral bone relationship: RO:0002298 UBERON:0002513 ! results in morphogenesis of endochondral bone [Term] id: GO:0060351 name: cartilage development involved in endochondral bone morphogenesis def: "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." [GOC:dph] is_a: GO:0051216 ! cartilage development intersection_of: GO:0051216 ! cartilage development intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060350 ! endochondral bone morphogenesis [Term] id: GO:0060359 name: response to ammonium ion alt_id: GO:1903717 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] synonym: "response to ammonia" EXACT [] is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium [Term] id: GO:0060361 name: flight def: "Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement." [GOC:dph] is_a: GO:0040011 ! locomotion property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0060363 name: cranial suture morphogenesis def: "The process in which any suture between cranial bones is generated and organized." [GOC:dph, GOC:pr, GOC:sl] is_a: GO:0097094 ! craniofacial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003685 ! results in morphogenesis of cranial suture relationship: RO:0002298 UBERON:0003685 ! results in morphogenesis of cranial suture [Term] id: GO:0060364 name: frontal suture morphogenesis def: "The process in which the frontal suture is generated and organized." [GOC:dph, GOC:sl] synonym: "interfrontal suture morphogenesis" EXACT [] is_a: GO:0060363 ! cranial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002490 ! results in morphogenesis of frontal suture relationship: RO:0002298 UBERON:0002490 ! results in morphogenesis of frontal suture [Term] id: GO:0060379 name: cardiac muscle cell myoblast differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:dph, GOC:tb] synonym: "cardiac myoblast differentiation" RELATED [GOC:dph, GOC:tb] synonym: "myocardial precursor cell differentiation" EXACT [GOC:mtg_heart] is_a: GO:0010002 ! cardioblast differentiation is_a: GO:0045445 ! myoblast differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000513 ! results in acquisition of features of cardiac muscle myoblast relationship: RO:0002315 CL:0000513 ! results in acquisition of features of cardiac muscle myoblast [Term] id: GO:0060404 name: axonemal microtubule depolymerization def: "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [GOC:cilia, GOC:dph, GOC:krc, GOC:tb] is_a: GO:0010938 ! cytoplasmic microtubule depolymerization is_a: GO:0061523 ! cilium disassembly intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: BFO:0000066 GO:0005930 ! occurs in axoneme relationship: BFO:0000066 GO:0005930 ! occurs in axoneme [Term] id: GO:0060408 name: regulation of acetylcholine metabolic process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008291 ! regulates acetylcholine metabolic process relationship: RO:0002211 GO:0008291 ! regulates acetylcholine metabolic process [Term] id: GO:0060409 name: positive regulation of acetylcholine metabolic process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008291 ! positively regulates acetylcholine metabolic process relationship: RO:0002213 GO:0008291 ! positively regulates acetylcholine metabolic process [Term] id: GO:0060411 name: cardiac septum morphogenesis alt_id: GO:0003280 def: "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." [GOC:dph, GOC:mtg_heart] synonym: "heart septum morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002099 ! results in morphogenesis of cardiac septum relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: part_of GO:0003279 ! cardiac septum development relationship: RO:0002298 UBERON:0002099 ! results in morphogenesis of cardiac septum [Term] id: GO:0060412 name: ventricular septum morphogenesis def: "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." [GOC:dph] synonym: "interventricular septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002094 ! results in morphogenesis of interventricular septum relationship: part_of GO:0003281 ! ventricular septum development relationship: RO:0002298 UBERON:0002094 ! results in morphogenesis of interventricular septum [Term] id: GO:0060413 name: atrial septum morphogenesis alt_id: GO:0003287 def: "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." [GOC:dph, GOC:mtg_heart] synonym: "interatrial septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002085 ! results in morphogenesis of interatrial septum relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: part_of GO:0003283 ! atrial septum development relationship: RO:0002298 UBERON:0002085 ! results in morphogenesis of interatrial septum [Term] id: GO:0060414 name: aorta smooth muscle tissue morphogenesis def: "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, GOC:dph, Wikipedia:Aorta] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004178 ! results in morphogenesis of aorta smooth muscle tissue relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035909 ! aorta morphogenesis relationship: part_of GO:0048745 ! smooth muscle tissue development relationship: RO:0002298 UBERON:0004178 ! results in morphogenesis of aorta smooth muscle tissue [Term] id: GO:0060415 name: muscle tissue morphogenesis def: "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0048729 ! tissue morphogenesis intersection_of: RO:0002298 UBERON:0002385 ! results in morphogenesis of muscle tissue relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048644 ! muscle organ morphogenesis relationship: RO:0002298 UBERON:0002385 ! results in morphogenesis of muscle tissue [Term] id: GO:0060419 name: heart growth def: "The increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0000948 ! results in growth of heart relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0007507 ! heart development relationship: RO:0002343 UBERON:0000948 ! results in growth of heart [Term] id: GO:0060420 name: regulation of heart growth def: "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060419 ! regulates heart growth relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0060419 ! regulates heart growth [Term] id: GO:0060421 name: positive regulation of heart growth def: "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0046622 ! positive regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060419 ! positively regulates heart growth relationship: RO:0002213 GO:0060419 ! positively regulates heart growth [Term] id: GO:0060425 name: lung morphogenesis def: "The process in which the anatomical structures of the lung are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002048 ! results in morphogenesis of lung relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development relationship: RO:0002298 UBERON:0002048 ! results in morphogenesis of lung [Term] id: GO:0060426 name: lung vasculature development def: "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary vasculature development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000102 ! results in development of lung vasculature relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development relationship: RO:0002296 UBERON:0000102 ! results in development of lung vasculature [Term] id: GO:0060427 name: lung connective tissue development def: "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary connective tissue development" EXACT [] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000114 ! results in development of lung connective tissue relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development relationship: RO:0002296 UBERON:0000114 ! results in development of lung connective tissue [Term] id: GO:0060428 name: lung epithelium development def: "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary epithelium development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000115 ! results in development of lung epithelium relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development relationship: RO:0002296 UBERON:0000115 ! results in development of lung epithelium [Term] id: GO:0060429 name: epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:dph, GOC:mtg_lung] subset: goslim_drosophila is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000483 ! results in development of epithelium relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002296 UBERON:0000483 ! results in development of epithelium [Term] id: GO:0060431 name: primary lung bud formation def: "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." [GOC:dph, GOC:mtg_lung] synonym: "lung formation" EXACT [GOC:dph] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048645 ! animal organ formation is_a: GO:0060441 ! epithelial tube branching involved in lung morphogenesis is_a: GO:0060572 ! morphogenesis of an epithelial bud intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002048 ! results in formation of anatomical entity lung relationship: RO:0002297 UBERON:0002048 ! results in formation of anatomical entity lung [Term] id: GO:0060433 name: bronchus development def: "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph] is_a: GO:0030323 ! respiratory tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002185 ! results in development of bronchus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060541 ! respiratory system development relationship: RO:0002296 UBERON:0002185 ! results in development of bronchus [Term] id: GO:0060434 name: bronchus morphogenesis def: "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002185 ! results in morphogenesis of bronchus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060433 ! bronchus development relationship: RO:0002298 UBERON:0002185 ! results in morphogenesis of bronchus [Term] id: GO:0060437 name: lung growth def: "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:dph] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0002048 ! results in growth of lung relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development relationship: RO:0002343 UBERON:0002048 ! results in growth of lung [Term] id: GO:0060438 name: trachea development def: "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001005 ! results in development of respiratory airway relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0060541 ! respiratory system development relationship: RO:0002296 UBERON:0001005 ! results in development of respiratory airway [Term] id: GO:0060439 name: trachea morphogenesis def: "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001005 ! results in morphogenesis of respiratory airway relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0060438 ! trachea development relationship: RO:0002298 UBERON:0001005 ! results in morphogenesis of respiratory airway [Term] id: GO:0060440 name: trachea formation def: "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001005 ! results in formation of anatomical entity respiratory airway relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0060439 ! trachea morphogenesis relationship: RO:0002297 UBERON:0001005 ! results in formation of anatomical entity respiratory airway [Term] id: GO:0060441 name: epithelial tube branching involved in lung morphogenesis def: "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:mtg_lung] synonym: "lung branching morphogenesis" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: part_of GO:0060425 ! lung morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060425 ! lung morphogenesis [Term] id: GO:0060450 name: positive regulation of hindgut contraction def: "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0043133 ! positively regulates hindgut contraction relationship: RO:0002213 GO:0043133 ! positively regulates hindgut contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060451 name: negative regulation of hindgut contraction def: "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0043133 ! negatively regulates hindgut contraction relationship: RO:0002212 GO:0043133 ! negatively regulates hindgut contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060452 name: positive regulation of cardiac muscle contraction def: "Any process that increases the frequency, rate or extent of cardiac muscle contraction." [GOC:dph, GOC:tb] is_a: GO:0045823 ! positive regulation of heart contraction is_a: GO:0045989 ! positive regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060048 ! positively regulates cardiac muscle contraction relationship: RO:0002213 GO:0060048 ! positively regulates cardiac muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060453 name: regulation of gastric acid secretion def: "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001696 ! regulates gastric acid secretion relationship: RO:0002211 GO:0001696 ! regulates gastric acid secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060454 name: positive regulation of gastric acid secretion def: "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001696 ! positively regulates gastric acid secretion relationship: RO:0002213 GO:0001696 ! positively regulates gastric acid secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060455 name: negative regulation of gastric acid secretion def: "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001696 ! negatively regulates gastric acid secretion relationship: RO:0002212 GO:0001696 ! negatively regulates gastric acid secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060456 name: positive regulation of digestive system process def: "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022600 ! positively regulates digestive system process relationship: RO:0002213 GO:0022600 ! positively regulates digestive system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060457 name: negative regulation of digestive system process def: "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022600 ! negatively regulates digestive system process relationship: RO:0002212 GO:0022600 ! negatively regulates digestive system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0060458 name: right lung development def: "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "right pulmonary development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002167 ! results in development of right lung relationship: RO:0002296 UBERON:0002167 ! results in development of right lung [Term] id: GO:0060459 name: left lung development def: "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "left pulmonary development" EXACT [GOC:dph] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002168 ! results in development of left lung relationship: RO:0002296 UBERON:0002168 ! results in development of left lung [Term] id: GO:0060460 name: left lung morphogenesis def: "The process in which anatomical structures of the left lung are generated and organized." [GOC:dph] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002168 ! results in morphogenesis of left lung relationship: part_of GO:0060459 ! left lung development relationship: RO:0002298 UBERON:0002168 ! results in morphogenesis of left lung [Term] id: GO:0060461 name: right lung morphogenesis def: "The process in which anatomical structures of the right lung are generated and organized." [GOC:dph, GOC:mtg_lung] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002167 ! results in morphogenesis of right lung relationship: part_of GO:0060458 ! right lung development relationship: RO:0002298 UBERON:0002167 ! results in morphogenesis of right lung [Term] id: GO:0060462 name: lung lobe development def: "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000101 ! results in development of lobe of lung relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development relationship: RO:0002296 UBERON:0000101 ! results in development of lobe of lung [Term] id: GO:0060463 name: lung lobe morphogenesis def: "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000101 ! results in morphogenesis of lobe of lung relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060462 ! lung lobe development relationship: RO:0002298 UBERON:0000101 ! results in morphogenesis of lobe of lung [Term] id: GO:0060464 name: lung lobe formation def: "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000101 ! results in formation of anatomical entity lobe of lung relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060463 ! lung lobe morphogenesis relationship: RO:0002297 UBERON:0000101 ! results in formation of anatomical entity lobe of lung [Term] id: GO:0060465 name: pharynx development def: "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." [GOC:dph, GOC:rk] synonym: "pharyngeal development" RELATED [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006562 ! results in development of pharynx relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0048565 ! digestive tract development relationship: RO:0002296 UBERON:0006562 ! results in development of pharynx [Term] id: GO:0060467 name: negative regulation of fertilization def: "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:dph] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009566 ! negatively regulates fertilization relationship: RO:0002212 GO:0009566 ! negatively regulates fertilization [Term] id: GO:0060468 name: prevention of polyspermy def: "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." [GOC:dph] synonym: "negative regulation of fertilization involved in egg activation" EXACT [GOC:dph] synonym: "polyspermy block" EXACT [GOC:dph] is_a: GO:0060467 ! negative regulation of fertilization intersection_of: GO:0060467 ! negative regulation of fertilization intersection_of: part_of GO:0007343 ! egg activation relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0007343 ! egg activation [Term] id: GO:0060474 name: positive regulation of flagellated sperm motility involved in capacitation def: "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence." [GOC:cilia, GOC:dph, GOC:krc] synonym: "positive regulation of sperm motility involved in capacitation" RELATED [] is_a: GO:0022414 ! reproductive process is_a: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: part_of GO:0048240 ! sperm capacitation relationship: part_of GO:0048240 ! sperm capacitation property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060479 name: lung cell differentiation def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary cell differentiation" EXACT [GOC:dph] is_a: GO:0030154 ! cell differentiation relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development [Term] id: GO:0060485 name: mesenchyme development def: "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:dph] synonym: "mesenchymal development" EXACT [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003104 ! results in development of mesenchyme relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0048513 ! animal organ development relationship: RO:0002296 UBERON:0003104 ! results in development of mesenchyme [Term] id: GO:0060487 name: lung epithelial cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." [GOC:dph] synonym: "pulmonary epithelial cell differentiation" RELATED [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060479 ! lung cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000082 ! results in acquisition of features of epithelial cell of lung relationship: part_of GO:0060428 ! lung epithelium development relationship: RO:0002315 CL:0000082 ! results in acquisition of features of epithelial cell of lung [Term] id: GO:0060491 name: regulation of cell projection assembly def: "Any process that modulates the rate, frequency, or extent of cell projection assembly." [GOC:dph, GOC:tb] synonym: "regulation of cell projection formation" RELATED [GOC:dph, GOC:tb] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030031 ! regulates cell projection assembly relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0030031 ! regulates cell projection assembly [Term] id: GO:0060495 name: cell-cell signaling involved in lung development def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." [GOC:dph, GOC:mtg_lung] synonym: "cell-cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0030324 ! lung development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development [Term] id: GO:0060496 name: mesenchymal-epithelial cell signaling involved in lung development def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung." [GOC:dph, GOC:mtg_lung] synonym: "mesenchymal-epithelial cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0060495 ! cell-cell signaling involved in lung development is_a: GO:0060638 ! mesenchymal-epithelial cell signaling intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling intersection_of: part_of GO:0030324 ! lung development [Term] id: GO:0060497 name: mesenchymal-endodermal cell signaling def: "Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell." [GOC:dph] synonym: "mesenchymal-endodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0008019 ! has start location mesenchymal cell intersection_of: RO:0002232 CL:0000223 ! has end location endodermal cell relationship: RO:0002231 CL:0008019 ! has start location mesenchymal cell relationship: RO:0002232 CL:0000223 ! has end location endodermal cell [Term] id: GO:0060501 name: positive regulation of epithelial cell proliferation involved in lung morphogenesis def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." [GOC:dph] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060502 ! positively regulates epithelial cell proliferation involved in lung morphogenesis relationship: RO:0002213 GO:0060502 ! positively regulates epithelial cell proliferation involved in lung morphogenesis [Term] id: GO:0060502 name: epithelial cell proliferation involved in lung morphogenesis def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." [GOC:dph] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0060425 ! lung morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060428 ! lung epithelium development [Term] id: GO:0060532 name: bronchus cartilage development def: "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary cartilage development" EXACT [] is_a: GO:0051216 ! cartilage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001956 ! results in development of cartilage of bronchus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060433 ! bronchus development relationship: RO:0002296 UBERON:0001956 ! results in development of cartilage of bronchus created_by: dph creation_date: 2009-04-10T08:12:06Z [Term] id: GO:0060533 name: bronchus cartilage morphogenesis def: "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs." [GOC:dph] is_a: GO:0060536 ! cartilage morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001956 ! results in morphogenesis of cartilage of bronchus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060434 ! bronchus morphogenesis relationship: part_of GO:0060532 ! bronchus cartilage development relationship: RO:0002298 UBERON:0001956 ! results in morphogenesis of cartilage of bronchus created_by: dph creation_date: 2009-04-10T08:47:41Z [Term] id: GO:0060534 name: trachea cartilage development def: "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051216 ! cartilage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003604 ! results in development of trachea cartilage relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060438 ! trachea development relationship: RO:0002296 UBERON:0003604 ! results in development of trachea cartilage created_by: dph creation_date: 2009-04-10T09:00:18Z [Term] id: GO:0060535 name: trachea cartilage morphogenesis def: "The process in which the anatomical structures of cartilage in the trachea are generated and organized." [GOC:dph] is_a: GO:0060536 ! cartilage morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003604 ! results in morphogenesis of trachea cartilage relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060439 ! trachea morphogenesis relationship: part_of GO:0060534 ! trachea cartilage development relationship: RO:0002298 UBERON:0003604 ! results in morphogenesis of trachea cartilage created_by: dph creation_date: 2009-04-10T09:07:48Z [Term] id: GO:0060536 name: cartilage morphogenesis def: "The process in which the anatomical structures of cartilage are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007844 ! results in morphogenesis of cartilage element relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0051216 ! cartilage development relationship: RO:0002298 UBERON:0007844 ! results in morphogenesis of cartilage element created_by: dph creation_date: 2009-04-10T09:13:27Z [Term] id: GO:0060537 name: muscle tissue development def: "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002385 ! results in development of muscle tissue relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0002385 ! results in development of muscle tissue created_by: dph creation_date: 2009-04-10T08:05:37Z [Term] id: GO:0060538 name: skeletal muscle organ development def: "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." [GOC:dph] is_a: GO:0007517 ! muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0014892 ! results in development of skeletal muscle organ, vertebrate relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0014892 ! results in development of skeletal muscle organ, vertebrate created_by: dph creation_date: 2009-04-10T08:25:12Z [Term] id: GO:0060539 name: diaphragm development def: "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." [GOC:dph] is_a: GO:0060538 ! skeletal muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001103 ! results in development of diaphragm relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0060541 ! respiratory system development relationship: RO:0002296 UBERON:0001103 ! results in development of diaphragm created_by: dph creation_date: 2009-04-10T08:44:56Z [Term] id: GO:0060540 name: diaphragm morphogenesis def: "The process in which the anatomical structures of the diaphragm are generated and organized." [GOC:dph] is_a: GO:0048644 ! muscle organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001103 ! results in morphogenesis of diaphragm relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0060539 ! diaphragm development relationship: RO:0002298 UBERON:0001103 ! results in morphogenesis of diaphragm created_by: dph creation_date: 2009-04-10T08:47:51Z [Term] id: GO:0060541 name: respiratory system development def: "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." [GOC:dph] subset: goslim_drosophila is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001004 ! results in development of respiratory system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0001004 ! results in development of respiratory system created_by: dph creation_date: 2009-04-10T08:55:42Z [Term] id: GO:0060560 name: developmental growth involved in morphogenesis def: "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph] synonym: "differential growth" EXACT [GOC:dph] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009653 ! anatomical structure morphogenesis created_by: dph creation_date: 2009-04-28T08:42:53Z [Term] id: GO:0060561 name: apoptotic process involved in morphogenesis def: "Any apoptotic process that contributes to the shaping of an anatomical structure." [GOC:dph, GOC:mtg_apoptosis] synonym: "apoptosis involved in development" RELATED [] synonym: "apoptosis involved in morphogenesis" NARROW [] synonym: "morphogenetic apoptosis" RELATED [GOC:dph] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009653 ! anatomical structure morphogenesis property_value: RO:0002161 NCBITaxon:4896 created_by: dph creation_date: 2009-04-28T09:17:27Z [Term] id: GO:0060562 name: epithelial tube morphogenesis def: "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003914 ! results in morphogenesis of epithelial tube relationship: RO:0002298 UBERON:0003914 ! results in morphogenesis of epithelial tube created_by: dph creation_date: 2009-04-28T09:33:36Z [Term] id: GO:0060563 name: neuroepithelial cell differentiation def: "The process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, GOC:tb] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000710 ! results in acquisition of features of neurecto-epithelial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002315 CL:0000710 ! results in acquisition of features of neurecto-epithelial cell created_by: dph creation_date: 2009-04-29T01:50:05Z [Term] id: GO:0060571 name: morphogenesis of an epithelial fold def: "The morphogenetic process in which an epithelial sheet bends along a linear axis." [GOC:dph] synonym: "epithelial folding" EXACT [GOC:dph] synonym: "folding of an epithelial sheet" RELATED [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005157 ! results in morphogenesis of epithelial fold relationship: RO:0002298 UBERON:0005157 ! results in morphogenesis of epithelial fold created_by: dph creation_date: 2009-04-30T09:27:17Z [Term] id: GO:0060572 name: morphogenesis of an epithelial bud def: "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." [GOC:dph] is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005153 ! results in morphogenesis of epithelial bud relationship: RO:0002298 UBERON:0005153 ! results in morphogenesis of epithelial bud created_by: dph creation_date: 2009-04-30T09:38:35Z [Term] id: GO:0060574 name: intestinal epithelial cell maturation def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." [GOC:dph, PMID:18824147] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0002563 ! results in maturation of intestinal epithelial cell relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0060576 ! intestinal epithelial cell development relationship: RO:0002299 CL:0002563 ! results in maturation of intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:10:41Z [Term] id: GO:0060575 name: intestinal epithelial cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002563 ! results in acquisition of features of intestinal epithelial cell relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0048565 ! digestive tract development relationship: RO:0002315 CL:0002563 ! results in acquisition of features of intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:17:56Z [Term] id: GO:0060576 name: intestinal epithelial cell development def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0002563 ! results in development of intestinal epithelial cell relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0060575 ! intestinal epithelial cell differentiation relationship: RO:0002296 CL:0002563 ! results in development of intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:20:24Z [Term] id: GO:0060577 name: pulmonary vein morphogenesis def: "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." [GOC:dph] synonym: "pulmonary venous blood vessel morphogenesis" RELATED [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002016 ! results in morphogenesis of pulmonary vein relationship: RO:0002298 UBERON:0002016 ! results in morphogenesis of pulmonary vein created_by: dph creation_date: 2009-05-06T08:44:04Z [Term] id: GO:0060578 name: superior vena cava morphogenesis def: "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001585 ! results in morphogenesis of anterior vena cava relationship: RO:0002298 UBERON:0001585 ! results in morphogenesis of anterior vena cava created_by: dph creation_date: 2009-05-06T08:47:21Z [Term] id: GO:0060581 name: cell fate commitment involved in pattern specification def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." [GOC:dph] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: part_of GO:0007389 ! pattern specification process relationship: part_of GO:0007389 ! pattern specification process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2009-05-07T12:40:55Z [Term] id: GO:0060591 name: chondroblast differentiation def: "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." [GOC:dph] synonym: "chondrocyte progenitor cell differentiation" RELATED [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000058 ! results in acquisition of features of chondroblast relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0051216 ! cartilage development relationship: RO:0002315 CL:0000058 ! results in acquisition of features of chondroblast created_by: dph creation_date: 2009-05-11T07:47:36Z [Term] id: GO:0060612 name: adipose tissue development def: "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." [GOC:dph] synonym: "adipogenesis" RELATED [GOC:mah, GOC:sl] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001013 ! results in development of adipose tissue relationship: part_of GO:0048513 ! animal organ development relationship: RO:0002296 UBERON:0001013 ! results in development of adipose tissue created_by: dph creation_date: 2009-05-15T12:36:28Z [Term] id: GO:0060623 name: regulation of chromosome condensation def: "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:dph, GOC:tb] is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030261 ! regulates chromosome condensation relationship: RO:0002211 GO:0030261 ! regulates chromosome condensation created_by: dph creation_date: 2009-05-18T02:12:13Z [Term] id: GO:0060627 name: regulation of vesicle-mediated transport def: "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016192 ! regulates vesicle-mediated transport relationship: RO:0002211 GO:0016192 ! regulates vesicle-mediated transport created_by: dph creation_date: 2009-05-18T02:29:43Z [Term] id: GO:0060632 name: regulation of microtubule-based movement def: "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007018 ! regulates microtubule-based movement relationship: RO:0002211 GO:0007018 ! regulates microtubule-based movement created_by: dph creation_date: 2009-05-18T03:07:02Z [Term] id: GO:0060638 name: mesenchymal-epithelial cell signaling def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted." [GOC:dph] synonym: "mesenchymal-epithelial cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0008019 ! has start location mesenchymal cell intersection_of: RO:0002232 CL:0000066 ! has end location epithelial cell relationship: RO:0002231 CL:0008019 ! has start location mesenchymal cell relationship: RO:0002232 CL:0000066 ! has end location epithelial cell created_by: dph creation_date: 2009-05-19T03:59:05Z [Term] id: GO:0060669 name: embryonic placenta morphogenesis def: "The process in which the embryonic placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0007106 ! results in morphogenesis of chorionic villus relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001892 ! embryonic placenta development relationship: RO:0002298 UBERON:0007106 ! results in morphogenesis of chorionic villus created_by: dph creation_date: 2009-06-02T09:33:37Z [Term] id: GO:0060670 name: branching involved in labyrinthine layer morphogenesis def: "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." [GOC:dph, PMID:16916377] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0060713 ! labyrinthine layer morphogenesis relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis created_by: dph creation_date: 2009-06-02T10:40:40Z [Term] id: GO:0060671 name: epithelial cell differentiation involved in embryonic placenta development def: "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." [GOC:dph, PMID:16916377] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: part_of GO:0060711 ! labyrinthine layer development created_by: dph creation_date: 2009-06-02T11:40:52Z [Term] id: GO:0060673 name: cell-cell signaling involved in placenta development def: "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377] synonym: "cell-cell signalling involved in placenta development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001890 ! placenta development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-02T12:58:03Z [Term] id: GO:0060674 name: placenta blood vessel development def: "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." [GOC:dph, PMID:16916377] is_a: GO:0001568 ! blood vessel development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001890 ! placenta development created_by: dph creation_date: 2009-06-02T01:09:43Z [Term] id: GO:0060675 name: ureteric bud morphogenesis def: "The process in which the ureteric bud is generated and organized." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0072171 ! mesonephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000084 ! results in morphogenesis of ureteric bud relationship: part_of GO:0001657 ! ureteric bud development relationship: RO:0002298 UBERON:0000084 ! results in morphogenesis of ureteric bud created_by: dph creation_date: 2009-06-02T01:31:41Z [Term] id: GO:0060676 name: ureteric bud formation def: "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." [GOC:dph, PMID:16916378] xref: Reactome:R-HSA-9830674 "Formation of the ureteric bud" is_a: GO:0072172 ! mesonephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000084 ! results in formation of anatomical entity ureteric bud relationship: part_of GO:0060675 ! ureteric bud morphogenesis relationship: RO:0002297 UBERON:0000084 ! results in formation of anatomical entity ureteric bud created_by: dph creation_date: 2009-06-02T01:47:23Z [Term] id: GO:0060684 name: epithelial-mesenchymal cell signaling def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted." [GOC:dph] synonym: "epithelial-mesenchymal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000066 ! has start location epithelial cell intersection_of: RO:0002232 CL:0008019 ! has end location mesenchymal cell relationship: RO:0002231 CL:0000066 ! has start location epithelial cell relationship: RO:0002232 CL:0008019 ! has end location mesenchymal cell created_by: dph creation_date: 2009-06-03T06:36:46Z [Term] id: GO:0060688 name: regulation of morphogenesis of a branching structure def: "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." [GOC:dph] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001763 ! regulates morphogenesis of a branching structure relationship: RO:0002211 GO:0001763 ! regulates morphogenesis of a branching structure property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2009-06-05T12:41:44Z [Term] id: GO:0060706 name: cell differentiation involved in embryonic placenta development def: "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-09T10:26:42Z [Term] id: GO:0060711 name: labyrinthine layer development def: "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003946 ! results in development of placenta labyrinth relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001892 ! embryonic placenta development relationship: RO:0002296 UBERON:0003946 ! results in development of placenta labyrinth created_by: dph creation_date: 2009-06-09T03:27:43Z [Term] id: GO:0060713 name: labyrinthine layer morphogenesis def: "The process in which the labyrinthine layer of the placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003946 ! results in morphogenesis of placenta labyrinth relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0060669 ! embryonic placenta morphogenesis relationship: part_of GO:0060711 ! labyrinthine layer development relationship: RO:0002298 UBERON:0003946 ! results in morphogenesis of placenta labyrinth created_by: dph creation_date: 2009-06-10T08:10:19Z [Term] id: GO:0060714 name: labyrinthine layer formation def: "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003946 ! results in formation of anatomical entity placenta labyrinth relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis relationship: RO:0002297 UBERON:0003946 ! results in formation of anatomical entity placenta labyrinth created_by: dph creation_date: 2009-06-10T08:13:14Z [Term] id: GO:0060716 name: labyrinthine layer blood vessel development def: "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GOC:dph] is_a: GO:0048568 ! embryonic organ development is_a: GO:0060674 ! placenta blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004183 ! results in development of placental labyrinth blood vessel relationship: part_of GO:0060711 ! labyrinthine layer development relationship: RO:0002296 UBERON:0004183 ! results in development of placental labyrinth blood vessel created_by: dph creation_date: 2009-06-11T09:04:38Z [Term] id: GO:0060717 name: chorion development def: "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." [GOC:dph] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003124 ! results in development of chorion membrane relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002296 UBERON:0003124 ! results in development of chorion membrane created_by: dph creation_date: 2009-06-11T02:37:50Z [Term] id: GO:0060718 name: chorionic trophoblast cell differentiation def: "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [CL:0011101, GOC:dph, PMID:16983341] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0011101 ! results in acquisition of features of chorionic trophoblast cell relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0060717 ! chorion development relationship: RO:0002315 CL:0011101 ! results in acquisition of features of chorionic trophoblast cell created_by: dph creation_date: 2009-06-11T02:48:27Z [Term] id: GO:0060719 name: chorionic trophoblast cell development def: "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0011101, GOC:16983341, GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0011101 ! results in development of chorionic trophoblast cell relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0060718 ! chorionic trophoblast cell differentiation relationship: RO:0002296 CL:0011101 ! results in development of chorionic trophoblast cell created_by: dph creation_date: 2009-06-11T02:58:45Z [Term] id: GO:0060722 name: cell proliferation involved in embryonic placenta development def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." [GOC:dph] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-12T12:46:04Z [Term] id: GO:0060723 name: regulation of cell proliferation involved in embryonic placenta development def: "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060722 ! regulates cell proliferation involved in embryonic placenta development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002211 GO:0060722 ! regulates cell proliferation involved in embryonic placenta development created_by: dph creation_date: 2009-06-12T12:50:23Z [Term] id: GO:0060788 name: ectodermal placode formation def: "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005085 ! results in formation of anatomical entity ectodermal placode relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0071697 ! ectodermal placode morphogenesis relationship: RO:0002297 UBERON:0005085 ! results in formation of anatomical entity ectodermal placode created_by: dph creation_date: 2009-08-04T12:15:57Z [Term] id: GO:0060790 name: tooth placode formation def: "The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005087 ! results in formation of anatomical entity tooth placode relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0042475 ! odontogenesis of dentin-containing tooth relationship: RO:0002297 UBERON:0005087 ! results in formation of anatomical entity tooth placode property_value: RO:0002161 NCBITaxon:8782 created_by: dph creation_date: 2009-08-04T12:21:47Z [Term] id: GO:0060795 name: cell fate commitment involved in formation of primary germ layer def: "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: part_of GO:0001704 ! formation of primary germ layer relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0001704 ! formation of primary germ layer created_by: dph creation_date: 2009-08-04T03:11:22Z [Term] id: GO:0060800 name: regulation of cell differentiation involved in embryonic placenta development def: "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060706 ! regulates cell differentiation involved in embryonic placenta development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002211 GO:0060706 ! regulates cell differentiation involved in embryonic placenta development created_by: dph creation_date: 2009-08-06T01:20:25Z [Term] id: GO:0060806 name: negative regulation of cell differentiation involved in embryonic placenta development def: "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060800 ! regulation of cell differentiation involved in embryonic placenta development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060706 ! negatively regulates cell differentiation involved in embryonic placenta development relationship: RO:0002212 GO:0060706 ! negatively regulates cell differentiation involved in embryonic placenta development created_by: dph creation_date: 2009-08-06T02:02:18Z [Term] id: GO:0060815 name: regulation of translation involved in anterior/posterior axis specification def: "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0006417 ! regulation of translation intersection_of: part_of GO:0009948 ! anterior/posterior axis specification relationship: part_of GO:0009948 ! anterior/posterior axis specification property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2009-08-07T10:02:31Z [Term] id: GO:0060837 name: blood vessel endothelial cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000071 ! results in acquisition of features of blood vessel endothelial cell relationship: part_of GO:0001568 ! blood vessel development relationship: RO:0002315 CL:0000071 ! results in acquisition of features of blood vessel endothelial cell created_by: dph creation_date: 2009-08-11T03:47:36Z [Term] id: GO:0060840 name: artery development def: "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001637 ! results in development of artery relationship: RO:0002296 UBERON:0001637 ! results in development of artery created_by: dph creation_date: 2009-08-12T10:10:51Z [Term] id: GO:0060841 name: venous blood vessel development def: "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001638 ! results in development of vein relationship: RO:0002296 UBERON:0001638 ! results in development of vein created_by: dph creation_date: 2009-08-12T10:14:07Z [Term] id: GO:0060842 name: arterial endothelial cell differentiation def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000413 ! results in acquisition of features of endothelial cell of artery relationship: RO:0002315 CL:1000413 ! results in acquisition of features of endothelial cell of artery created_by: dph creation_date: 2009-08-12T10:41:34Z [Term] id: GO:0060843 name: venous endothelial cell differentiation def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002543 ! results in acquisition of features of vein endothelial cell relationship: RO:0002315 CL:0002543 ! results in acquisition of features of vein endothelial cell created_by: dph creation_date: 2009-08-12T10:43:40Z [Term] id: GO:0060887 name: limb epidermis development def: "The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0098773 ! skin epidermis development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009200 ! results in development of limb epidermis relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0060173 ! limb development relationship: RO:0002296 UBERON:0009200 ! results in development of limb epidermis created_by: dph creation_date: 2009-08-13T12:39:39Z [Term] id: GO:0060896 name: neural plate pattern specification def: "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:sdb_2009, GOC:tb] xref: Reactome:R-HSA-9834899 "Specification of the neural plate border" is_a: GO:0007389 ! pattern specification process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2009-08-13T02:06:27Z [Term] id: GO:0060897 name: neural plate regionalization def: "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0003002 ! regionalization is_a: GO:0060896 ! neural plate pattern specification property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2009-08-13T02:09:04Z [Term] id: GO:0060900 name: embryonic camera-type eye formation def: "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis created_by: dph creation_date: 2009-08-13T02:26:54Z [Term] id: GO:0060914 name: heart formation def: "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." [GOC:mtg_heart] synonym: "cardiogenesis" RELATED [GOC:mtg_heart] xref: Reactome:R-HSA-9733709 "Cardiogenesis" is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000948 ! results in formation of anatomical entity heart relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003007 ! heart morphogenesis relationship: RO:0002297 UBERON:0000948 ! results in formation of anatomical entity heart created_by: dph creation_date: 2009-09-17T09:02:13Z [Term] id: GO:0060915 name: mesenchymal cell differentiation involved in lung development def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0030324 ! lung development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development created_by: dph creation_date: 2009-09-18T11:45:33Z [Term] id: GO:0060916 name: mesenchymal cell proliferation involved in lung development def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0030324 ! lung development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0030324 ! lung development created_by: dph creation_date: 2009-09-18T11:50:17Z [Term] id: GO:0060920 name: cardiac pacemaker cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "pacemaker cell differentiation" BROAD [] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002072 ! results in acquisition of features of nodal myocyte relationship: RO:0002315 CL:0002072 ! results in acquisition of features of nodal myocyte created_by: dph creation_date: 2009-09-29T11:01:31Z [Term] id: GO:0060921 name: sinoatrial node cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell differentiation" EXACT [GOC:mtg_heart] synonym: "SAN cell differentiation" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node cell differentiation" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000409 ! results in acquisition of features of myocyte of sinoatrial node relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003163 ! sinoatrial node development relationship: RO:0002315 CL:1000409 ! results in acquisition of features of myocyte of sinoatrial node created_by: dph creation_date: 2009-09-29T11:03:30Z [Term] id: GO:0060922 name: atrioventricular node cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." [GOC:mtg_heart] synonym: "AV node cell differentiation" RELATED [GOC:mtg_heart] is_a: GO:0003292 ! cardiac septum cell differentiation is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000410 ! results in acquisition of features of myocyte of atrioventricular node relationship: part_of GO:0003162 ! atrioventricular node development relationship: RO:0002315 CL:1000410 ! results in acquisition of features of myocyte of atrioventricular node created_by: dph creation_date: 2009-09-29T11:07:06Z [Term] id: GO:0060926 name: cardiac pacemaker cell development def: "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "pacemaker cell development" BROAD [] is_a: GO:0055013 ! cardiac muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0002072 ! results in development of nodal myocyte relationship: part_of GO:0060920 ! cardiac pacemaker cell differentiation relationship: RO:0002296 CL:0002072 ! results in development of nodal myocyte created_by: dph creation_date: 2009-09-29T11:51:55Z [Term] id: GO:0060928 name: atrioventricular node cell development def: "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "AV node cell development" EXACT [GOC:mtg_heart] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:1000410 ! results in development of myocyte of atrioventricular node relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060922 ! atrioventricular node cell differentiation relationship: RO:0002296 CL:1000410 ! results in development of myocyte of atrioventricular node created_by: dph creation_date: 2009-09-29T11:59:26Z [Term] id: GO:0060931 name: sinoatrial node cell development def: "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell development" EXACT [GOC:mtg_heart] synonym: "SAN cell development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node cell development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:1000409 ! results in development of myocyte of sinoatrial node relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060921 ! sinoatrial node cell differentiation relationship: RO:0002296 CL:1000409 ! results in development of myocyte of sinoatrial node created_by: dph creation_date: 2009-09-29T12:05:47Z [Term] id: GO:0060932 name: His-Purkinje system cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010007 ! results in acquisition of features of His-Purkinje system cell relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0003164 ! His-Purkinje system development relationship: RO:0002315 CL:0010007 ! results in acquisition of features of His-Purkinje system cell created_by: dph creation_date: 2009-09-29T01:10:32Z [Term] id: GO:0060933 name: His-Purkinje system cell development def: "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0010007 ! results in development of His-Purkinje system cell relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0060932 ! His-Purkinje system cell differentiation relationship: RO:0002296 CL:0010007 ! results in development of His-Purkinje system cell created_by: dph creation_date: 2009-09-29T01:15:02Z [Term] id: GO:0060935 name: cardiac fibroblast cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002548 ! results in acquisition of features of fibroblast of cardiac tissue relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002315 CL:0002548 ! results in acquisition of features of fibroblast of cardiac tissue created_by: dph creation_date: 2009-09-29T01:20:04Z [Term] id: GO:0060936 name: cardiac fibroblast cell development def: "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0002548 ! results in development of fibroblast of cardiac tissue relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060935 ! cardiac fibroblast cell differentiation relationship: RO:0002296 CL:0002548 ! results in development of fibroblast of cardiac tissue created_by: dph creation_date: 2009-09-29T01:23:03Z [Term] id: GO:0060945 name: cardiac neuron differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." [GOC:mtg_heart] synonym: "heart neuron differentiation" EXACT [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0048934 ! peripheral nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010022 ! results in acquisition of features of cardiac neuron relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048483 ! autonomic nervous system development relationship: RO:0002315 CL:0010022 ! results in acquisition of features of cardiac neuron created_by: dph creation_date: 2009-09-29T02:45:33Z [Term] id: GO:0060946 name: cardiac blood vessel endothelial cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010006 ! results in acquisition of features of cardiac blood vessel endothelial cell relationship: RO:0002315 CL:0010006 ! results in acquisition of features of cardiac blood vessel endothelial cell created_by: dph creation_date: 2009-09-29T02:48:55Z [Term] id: GO:0060950 name: cardiac glial cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart] is_a: GO:0010001 ! glial cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0010020 ! results in acquisition of features of cardiac glial cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002315 CL:0010020 ! results in acquisition of features of cardiac glial cell created_by: dph creation_date: 2009-09-29T03:06:37Z [Term] id: GO:0060952 name: cardiac glial cell development def: "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." [GOC:mtg_heart] is_a: GO:0021782 ! glial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0010020 ! results in development of cardiac glial cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060950 ! cardiac glial cell differentiation relationship: RO:0002296 CL:0010020 ! results in development of cardiac glial cell created_by: dph creation_date: 2009-09-29T03:09:24Z [Term] id: GO:0060956 name: endocardial cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002350 ! results in acquisition of features of endocardial cell relationship: part_of GO:0003157 ! endocardium development relationship: RO:0002315 CL:0002350 ! results in acquisition of features of endocardial cell created_by: dph creation_date: 2009-09-29T03:20:39Z [Term] id: GO:0060958 name: endocardial cell development def: "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart] is_a: GO:0001885 ! endothelial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0002350 ! results in development of endocardial cell relationship: part_of GO:0060956 ! endocardial cell differentiation relationship: RO:0002296 CL:0002350 ! results in development of endocardial cell created_by: dph creation_date: 2009-09-29T03:26:59Z [Term] id: GO:0060959 name: cardiac neuron development def: "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "heart neuron development" EXACT [GOC:mtg_heart] is_a: GO:0048935 ! peripheral nervous system neuron development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0010022 ! results in development of cardiac neuron relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060945 ! cardiac neuron differentiation relationship: RO:0002296 CL:0010022 ! results in development of cardiac neuron created_by: dph creation_date: 2009-09-30T10:14:56Z [Term] id: GO:0060973 name: cell migration involved in heart development def: "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." [GOC:mtg_heart] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0007507 ! heart development relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0007507 ! heart development created_by: dph creation_date: 2009-10-06T10:53:49Z [Term] id: GO:0060974 name: cell migration involved in heart formation def: "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060914 ! heart formation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060914 ! heart formation created_by: dph creation_date: 2009-10-06T10:56:33Z [Term] id: GO:0060976 name: coronary vasculature development def: "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "cardiac blood vessel development" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature development" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart vasculature development" EXACT [GOC:mtg_heart] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003498 ! results in development of heart blood vessel relationship: part_of GO:0007507 ! heart development relationship: RO:0002296 UBERON:0003498 ! results in development of heart blood vessel created_by: dph creation_date: 2009-10-06T12:15:23Z [Term] id: GO:0060977 name: coronary vasculature morphogenesis def: "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:mtg_heart] synonym: "cardiac blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart vasculature morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003498 ! results in morphogenesis of heart blood vessel relationship: part_of GO:0060976 ! coronary vasculature development relationship: RO:0002298 UBERON:0003498 ! results in morphogenesis of heart blood vessel created_by: dph creation_date: 2009-10-06T12:28:23Z [Term] id: GO:0060978 name: angiogenesis involved in coronary vascular morphogenesis def: "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." [GOC:mtg_heart] synonym: "angiogenesis involved in cardiac vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "angiogenesis involved in heart vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel angiogenesis" EXACT [GOC:mtg_heart] synonym: "coronary vasculature angiogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001525 ! angiogenesis intersection_of: GO:0001525 ! angiogenesis intersection_of: part_of GO:0060976 ! coronary vasculature development relationship: part_of GO:0060977 ! coronary vasculature morphogenesis created_by: dph creation_date: 2009-10-06T02:02:12Z [Term] id: GO:0060979 name: vasculogenesis involved in coronary vascular morphogenesis def: "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." [GOC:mtg_heart] synonym: "coronary vasculogenesis" EXACT [GOC:mtg_heart] synonym: "vasculogenesis involved in coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: part_of GO:0060977 ! coronary vasculature morphogenesis relationship: part_of GO:0060977 ! coronary vasculature morphogenesis created_by: dph creation_date: 2009-10-06T02:19:42Z [Term] id: GO:0060980 name: cell migration involved in coronary vasculogenesis def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." [GOC:mtg_heart] is_a: GO:0035441 ! cell migration involved in vasculogenesis is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis relationship: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis created_by: dph creation_date: 2009-10-06T02:33:06Z [Term] id: GO:0060981 name: cell migration involved in coronary angiogenesis def: "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis created_by: dph creation_date: 2009-10-06T02:49:12Z [Term] id: GO:0060986 name: endocrine hormone secretion def: "The regulated release of a hormone into the circulatory system." [GOC:dph] is_a: GO:0046879 ! hormone secretion relationship: part_of GO:0050886 ! endocrine process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2010-01-11T09:03:48Z [Term] id: GO:0060993 name: kidney morphogenesis def: "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002113 ! results in morphogenesis of kidney relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002298 UBERON:0002113 ! results in morphogenesis of kidney created_by: dph creation_date: 2010-01-19T08:16:55Z [Term] id: GO:0060995 name: cell-cell signaling involved in kidney development def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in kidney development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001822 ! kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development created_by: dph creation_date: 2010-01-19T08:33:40Z [Term] id: GO:0061004 name: pattern specification involved in kidney development def: "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "kidney pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney pattern specification" EXACT [GOC:mtg_kidney_jan10] synonym: "pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001822 ! kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: part_of GO:0072048 ! renal system pattern specification created_by: dph creation_date: 2010-01-21T09:05:54Z [Term] id: GO:0061005 name: cell differentiation involved in kidney development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001822 ! kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development created_by: dph creation_date: 2010-01-21T09:13:55Z [Term] id: GO:0061006 name: regulation of cell proliferation involved in kidney morphogenesis def: "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0042127 ! regulation of cell population proliferation intersection_of: part_of GO:0060993 ! kidney morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060993 ! kidney morphogenesis created_by: dph creation_date: 2010-01-21T11:25:23Z [Term] id: GO:0061007 name: hepaticobiliary system process def: "A system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] subset: goslim_generic synonym: "hepatobiliary system process" EXACT [GOC:dph] is_a: GO:0003008 ! system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2010-01-22T09:09:10Z [Term] id: GO:0061008 name: hepaticobiliary system development def: "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] synonym: "hepatobiliary system development" EXACT [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002423 ! results in development of hepatobiliary system relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0002423 ! results in development of hepatobiliary system created_by: dph creation_date: 2010-01-22T09:11:59Z [Term] id: GO:0061009 name: common bile duct development def: "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine." [PMID:20614624] synonym: "bile duct development" EXACT [GOC:dph] synonym: "CBD development" EXACT [PMID:20614624] synonym: "EHBD development" BROAD [PMID:20614624] synonym: "extrahepatic bile duct development" BROAD [PMID:20614624] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002394 ! results in development of bile duct relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: RO:0002296 UBERON:0002394 ! results in development of bile duct created_by: dph creation_date: 2010-01-22T09:17:13Z [Term] id: GO:0061010 name: gallbladder development def: "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002110 ! results in development of gallbladder relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: RO:0002296 UBERON:0002110 ! results in development of gallbladder created_by: dph creation_date: 2010-01-22T09:38:44Z [Term] id: GO:0061011 name: hepatic duct development def: "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." [GOC:dph, PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001175 ! results in development of common hepatic duct relationship: RO:0002296 UBERON:0001175 ! results in development of common hepatic duct created_by: dph creation_date: 2010-01-22T09:44:39Z [Term] id: GO:0061017 name: hepatoblast differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." [GOC:dph, PMID:15226394] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000488 ! results in acquisition of features of cholangiocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001889 ! liver development relationship: RO:0002315 CL:1000488 ! results in acquisition of features of cholangiocyte created_by: dph creation_date: 2010-02-02T09:08:03Z [Term] id: GO:0061024 name: membrane organization alt_id: GO:0016044 alt_id: GO:0044802 def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] synonym: "membrane organization and biogenesis" RELATED [GOC:mah] synonym: "single-organism membrane organization" RELATED [] xref: Reactome:R-HSA-199991 "Membrane Trafficking" is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0016020 ! results in organization of membrane relationship: RO:0002592 GO:0016020 ! results in organization of membrane created_by: jl creation_date: 2010-02-08T02:43:11Z [Term] id: GO:0061025 name: membrane fusion alt_id: GO:0006944 alt_id: GO:0044801 def: "The membrane organization process that joins two lipid bilayers to form a single membrane." [GOC:dph, GOC:tb] subset: goslim_yeast synonym: "cellular membrane fusion" EXACT [] synonym: "single-organism membrane fusion" RELATED [] xref: Wikipedia:Lipid_bilayer_fusion is_a: GO:0061024 ! membrane organization intersection_of: GO:0061024 ! membrane organization intersection_of: RO:0012008 GO:0016020 ! results in fusion of membrane relationship: RO:0012008 GO:0016020 ! results in fusion of membrane created_by: jl creation_date: 2010-02-08T02:48:06Z [Term] id: GO:0061027 name: umbilical cord development def: "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002331 ! results in development of umbilical cord relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002296 UBERON:0002331 ! results in development of umbilical cord created_by: dph creation_date: 2010-02-09T09:09:22Z [Term] id: GO:0061032 name: visceral serous pericardium development def: "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." [GOC:dph, GOC:yaf] synonym: "epicardium development" EXACT [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002425 ! results in development of visceral serous pericardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060039 ! pericardium development relationship: RO:0002296 UBERON:0002425 ! results in development of visceral serous pericardium created_by: dph creation_date: 2010-02-09T09:52:49Z [Term] id: GO:0061035 name: regulation of cartilage development def: "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051216 ! regulates cartilage development relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0051216 ! regulates cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061036 name: positive regulation of cartilage development def: "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051216 ! positively regulates cartilage development relationship: RO:0002213 GO:0051216 ! positively regulates cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061037 name: negative regulation of cartilage development def: "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051216 ! negatively regulates cartilage development relationship: RO:0002212 GO:0051216 ! negatively regulates cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061038 name: uterus morphogenesis def: "The process in which anatomical structures of the uterus are generated and organized." [GOC:BHF, GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000995 ! results in morphogenesis of uterus relationship: in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0060065 ! uterus development relationship: RO:0002298 UBERON:0000995 ! results in morphogenesis of uterus created_by: dph creation_date: 2010-02-22T11:12:35Z [Term] id: GO:0061040 name: female gonad morphogenesis def: "The process in which a female gonad is generated and organized." [GOC:BHF, GOC:dph] synonym: "ovary morphogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0035262 ! gonad morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000992 ! results in morphogenesis of ovary relationship: part_of GO:0008585 ! female gonad development relationship: RO:0002298 UBERON:0000992 ! results in morphogenesis of ovary created_by: dph creation_date: 2010-02-22T11:29:28Z [Term] id: GO:0061046 name: regulation of branching involved in lung morphogenesis def: "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060441 ! regulates epithelial tube branching involved in lung morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0060441 ! regulates epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:41:38Z [Term] id: GO:0061047 name: positive regulation of branching involved in lung morphogenesis def: "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060441 ! positively regulates epithelial tube branching involved in lung morphogenesis relationship: RO:0002213 GO:0060441 ! positively regulates epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:50:01Z [Term] id: GO:0061048 name: negative regulation of branching involved in lung morphogenesis def: "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060441 ! negatively regulates epithelial tube branching involved in lung morphogenesis relationship: RO:0002212 GO:0060441 ! negatively regulates epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:51:31Z [Term] id: GO:0061049 name: cell growth involved in cardiac muscle cell development def: "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] synonym: "cardiac muscle cell hypertrophy" RELATED [GOC:dph] synonym: "cardiomyocyte growth" RELATED [GOC:dph] synonym: "heart muscle cell growth" RELATED [GOC:dph] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0016049 ! cell growth intersection_of: part_of GO:0055013 ! cardiac muscle cell development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003301 ! physiological cardiac muscle hypertrophy relationship: part_of GO:0055013 ! cardiac muscle cell development created_by: dph creation_date: 2010-02-25T12:56:07Z [Term] id: GO:0061050 name: regulation of cell growth involved in cardiac muscle cell development def: "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061049 ! regulates cell growth involved in cardiac muscle cell development relationship: RO:0002211 GO:0061049 ! regulates cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:05:16Z [Term] id: GO:0061051 name: positive regulation of cell growth involved in cardiac muscle cell development def: "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010613 ! positive regulation of cardiac muscle hypertrophy is_a: GO:0030307 ! positive regulation of cell growth is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061049 ! positively regulates cell growth involved in cardiac muscle cell development relationship: RO:0002213 GO:0061049 ! positively regulates cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:08:08Z [Term] id: GO:0061052 name: negative regulation of cell growth involved in cardiac muscle cell development def: "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010614 ! negative regulation of cardiac muscle hypertrophy is_a: GO:0030308 ! negative regulation of cell growth is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061049 ! negatively regulates cell growth involved in cardiac muscle cell development relationship: RO:0002212 GO:0061049 ! negatively regulates cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:11:30Z [Term] id: GO:0061053 name: somite development def: "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:dph] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002329 ! results in development of somite relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0009790 ! embryo development relationship: RO:0002296 UBERON:0002329 ! results in development of somite created_by: dph creation_date: 2010-03-02T12:05:13Z [Term] id: GO:0061054 name: dermatome development def: "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004016 ! results in development of dermatome relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0061053 ! somite development relationship: RO:0002296 UBERON:0004016 ! results in development of dermatome created_by: dph creation_date: 2010-03-02T12:07:37Z [Term] id: GO:0061055 name: myotome development def: "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003082 ! results in development of myotome relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0061053 ! somite development relationship: RO:0002296 UBERON:0003082 ! results in development of myotome created_by: dph creation_date: 2010-03-02T12:11:01Z [Term] id: GO:0061056 name: sclerotome development def: "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003089 ! results in development of sclerotome relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061053 ! somite development relationship: RO:0002296 UBERON:0003089 ! results in development of sclerotome created_by: dph creation_date: 2010-03-02T12:12:40Z [Term] id: GO:0061061 name: muscle structure development def: "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph] subset: goslim_drosophila is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005090 ! results in development of muscle structure relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0005090 ! results in development of muscle structure created_by: dph creation_date: 2010-03-09T08:55:14Z [Term] id: GO:0061062 name: regulation of nematode larval development def: "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048580 ! regulation of post-embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002119 ! regulates nematode larval development relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0002119 ! regulates nematode larval development created_by: dph creation_date: 2010-03-11T12:59:21Z [Term] id: GO:0061063 name: positive regulation of nematode larval development def: "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048582 ! positive regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002119 ! positively regulates nematode larval development relationship: RO:0002213 GO:0002119 ! positively regulates nematode larval development created_by: dph creation_date: 2010-03-11T01:03:34Z [Term] id: GO:0061064 name: negative regulation of nematode larval development def: "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048581 ! negative regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002119 ! negatively regulates nematode larval development relationship: RO:0002212 GO:0002119 ! negatively regulates nematode larval development created_by: dph creation_date: 2010-03-11T01:04:39Z [Term] id: GO:0061068 name: urethra development def: "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000057 ! results in development of urethra relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0072001 ! renal system development relationship: RO:0002296 UBERON:0000057 ! results in development of urethra created_by: dph creation_date: 2010-03-12T08:24:52Z [Term] id: GO:0061069 name: male urethra development def: "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001333 ! results in development of male urethra relationship: RO:0002296 UBERON:0001333 ! results in development of male urethra created_by: dph creation_date: 2010-03-12T08:28:19Z [Term] id: GO:0061070 name: female urethra development def: "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001334 ! results in development of female urethra relationship: RO:0002296 UBERON:0001334 ! results in development of female urethra created_by: dph creation_date: 2010-03-12T08:29:43Z [Term] id: GO:0061071 name: urethra epithelium development def: "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." [GOC:dph] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002325 ! results in development of epithelium of urethra relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061068 ! urethra development relationship: RO:0002296 UBERON:0002325 ! results in development of epithelium of urethra created_by: dph creation_date: 2010-03-12T08:36:53Z [Term] id: GO:0061072 name: iris morphogenesis def: "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001769 ! results in morphogenesis of iris relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: RO:0002298 UBERON:0001769 ! results in morphogenesis of iris created_by: dph creation_date: 2010-03-16T10:48:42Z [Term] id: GO:0061073 name: ciliary body morphogenesis def: "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001775 ! results in morphogenesis of ciliary body relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: RO:0002298 UBERON:0001775 ! results in morphogenesis of ciliary body created_by: dph creation_date: 2010-03-16T10:55:19Z [Term] id: GO:0061074 name: regulation of neural retina development def: "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003407 ! regulates neural retina development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003407 ! regulates neural retina development created_by: dph creation_date: 2010-03-16T11:47:05Z [Term] id: GO:0061075 name: positive regulation of neural retina development def: "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902868 ! positive regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003407 ! positively regulates neural retina development relationship: RO:0002213 GO:0003407 ! positively regulates neural retina development created_by: dph creation_date: 2010-03-16T11:59:48Z [Term] id: GO:0061076 name: negative regulation of neural retina development def: "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902867 ! negative regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003407 ! negatively regulates neural retina development relationship: RO:0002212 GO:0003407 ! negatively regulates neural retina development created_by: dph creation_date: 2010-03-16T12:46:11Z [Term] id: GO:0061080 name: right horn of sinus venosus development def: "The progression of the right horn of the sinus venosus from its formation to the mature structure." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005092 ! results in development of right horn of sinus venosus relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003235 ! sinus venosus development relationship: RO:0002296 UBERON:0005092 ! results in development of right horn of sinus venosus created_by: dph creation_date: 2010-04-08T02:45:10Z [Term] id: GO:0061100 name: lung neuroendocrine cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." [GOC:dph, PMID:9126746] is_a: GO:0061101 ! neuroendocrine cell differentiation is_a: GO:0061140 ! lung secretory cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000223 ! results in acquisition of features of pulmonary neuroendocrine cell relationship: RO:0002315 CL:1000223 ! results in acquisition of features of pulmonary neuroendocrine cell created_by: dph creation_date: 2010-04-27T03:28:46Z [Term] id: GO:0061101 name: neuroendocrine cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." [GOC:dph] is_a: GO:0030182 ! neuron differentiation is_a: GO:0060563 ! neuroepithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000165 ! results in acquisition of features of neuroendocrine cell relationship: RO:0002315 CL:0000165 ! results in acquisition of features of neuroendocrine cell created_by: dph creation_date: 2010-04-28T09:42:20Z [Term] id: GO:0061102 name: stomach neuroendocrine cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746] synonym: "gastric neuroendocrine cell differentiation" RELATED [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000222 ! results in acquisition of features of stomach neuroendocrine cell relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0062094 ! stomach development relationship: RO:0002315 CL:1000222 ! results in acquisition of features of stomach neuroendocrine cell created_by: dph creation_date: 2010-04-28T09:47:07Z [Term] id: GO:0061105 name: regulation of stomach neuroendocrine cell differentiation def: "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061102 ! regulates stomach neuroendocrine cell differentiation relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0061102 ! regulates stomach neuroendocrine cell differentiation created_by: dph creation_date: 2010-04-29T12:19:37Z [Term] id: GO:0061106 name: negative regulation of stomach neuroendocrine cell differentiation def: "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0061105 ! regulation of stomach neuroendocrine cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061102 ! negatively regulates stomach neuroendocrine cell differentiation relationship: RO:0002212 GO:0061102 ! negatively regulates stomach neuroendocrine cell differentiation created_by: dph creation_date: 2010-04-29T12:23:05Z [Term] id: GO:0061107 name: seminal vesicle development def: "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." [GOC:dph] is_a: GO:0048608 ! reproductive structure development is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000998 ! results in development of seminal vesicle relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002296 UBERON:0000998 ! results in development of seminal vesicle created_by: dph creation_date: 2010-04-30T10:17:30Z [Term] id: GO:0061108 name: seminal vesicle epithelium development def: "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004805 ! results in development of seminal vesicle epithelium relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0061107 ! seminal vesicle development relationship: RO:0002296 UBERON:0004805 ! results in development of seminal vesicle epithelium created_by: dph creation_date: 2010-04-30T10:19:54Z [Term] id: GO:0061109 name: dense core granule organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells." [GOC:dph] synonym: "dense core granule organisation" EXACT [GOC:mah] is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031045 ! results in organization of dense core granule relationship: RO:0002592 GO:0031045 ! results in organization of dense core granule created_by: dph creation_date: 2010-05-01T09:34:37Z [Term] id: GO:0061111 name: epithelial-mesenchymal cell signaling involved in lung development def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph] synonym: "epithelial-mesenchymal cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0060495 ! cell-cell signaling involved in lung development is_a: GO:0060684 ! epithelial-mesenchymal cell signaling intersection_of: GO:0060684 ! epithelial-mesenchymal cell signaling intersection_of: part_of GO:0030324 ! lung development created_by: dph creation_date: 2010-05-05T11:14:38Z [Term] id: GO:0061113 name: pancreas morphogenesis def: "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001264 ! results in morphogenesis of pancreas relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0031016 ! pancreas development relationship: RO:0002298 UBERON:0001264 ! results in morphogenesis of pancreas created_by: dph creation_date: 2010-05-05T11:55:30Z [Term] id: GO:0061114 name: branching involved in pancreas morphogenesis def: "The process in which the branches of the pancreas are generated and organized." [GOC:dph] is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0061113 ! pancreas morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061113 ! pancreas morphogenesis created_by: dph creation_date: 2010-05-05T12:03:04Z [Term] id: GO:0061117 name: negative regulation of heart growth def: "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:hjd] is_a: GO:0046621 ! negative regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060419 ! negatively regulates heart growth relationship: RO:0002212 GO:0060419 ! negatively regulates heart growth created_by: dph creation_date: 2010-05-17T07:31:28Z [Term] id: GO:0061130 name: pancreatic bud formation def: "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." [GOC:dph] is_a: GO:0048645 ! animal organ formation is_a: GO:0061114 ! branching involved in pancreas morphogenesis is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003922 ! results in formation of anatomical entity pancreatic epithelial bud relationship: RO:0002297 UBERON:0003922 ! results in formation of anatomical entity pancreatic epithelial bud created_by: dph creation_date: 2010-05-17T09:33:40Z [Term] id: GO:0061138 name: morphogenesis of a branching epithelium def: "The process in which the anatomical structures of a branched epithelium are generated and organized." [GOC:dph] is_a: GO:0001763 ! morphogenesis of a branching structure is_a: GO:0002009 ! morphogenesis of an epithelium created_by: dph creation_date: 2010-05-25T09:05:34Z [Term] id: GO:0061140 name: lung secretory cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." [GOC:dph] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000272 ! results in acquisition of features of lung secretory cell relationship: RO:0002315 CL:1000272 ! results in acquisition of features of lung secretory cell created_by: dph creation_date: 2010-05-25T09:28:53Z [Term] id: GO:0061147 name: endocardial endothelium development def: "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] is_a: GO:0003158 ! endothelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005316 ! results in development of endocardial endothelium relationship: part_of GO:0003157 ! endocardium development relationship: RO:0002296 UBERON:0005316 ! results in development of endocardial endothelium created_by: dph creation_date: 2010-06-03T09:15:31Z [Term] id: GO:0061148 name: extracellular matrix organization involved in endocardium development def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] synonym: "extracellular matrix organisation involved in endocardium development" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0030198 ! extracellular matrix organization intersection_of: part_of GO:0003157 ! endocardium development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003157 ! endocardium development created_by: dph creation_date: 2010-06-03T09:18:02Z [Term] id: GO:0061152 name: trachea submucosa development def: "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea." [GOC:dph, GOC:yaf] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002202 ! results in development of submucosa of trachea relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060438 ! trachea development relationship: RO:0002296 UBERON:0002202 ! results in development of submucosa of trachea created_by: dph creation_date: 2010-06-07T09:58:40Z [Term] id: GO:0061153 name: trachea gland development def: "The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection." [GOC:dph] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005203 ! results in development of trachea gland relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061152 ! trachea submucosa development relationship: RO:0002296 UBERON:0005203 ! results in development of trachea gland created_by: dph creation_date: 2010-06-07T10:10:51Z [Term] id: GO:0061154 name: endothelial tube morphogenesis def: "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:dph, GOC:yaf] is_a: GO:0003159 ! morphogenesis of an endothelium is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003915 ! results in morphogenesis of endothelial tube relationship: RO:0002298 UBERON:0003915 ! results in morphogenesis of endothelial tube created_by: dph creation_date: 2010-06-15T09:05:00Z [Term] id: GO:0061155 name: pulmonary artery endothelial tube morphogenesis def: "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." [GOC:dph, GOC:yaf] is_a: GO:0061154 ! endothelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005317 ! results in morphogenesis of pulmonary artery endothelium relationship: part_of GO:0061156 ! pulmonary artery morphogenesis relationship: RO:0002298 UBERON:0005317 ! results in morphogenesis of pulmonary artery endothelium created_by: dph creation_date: 2010-06-15T09:09:04Z [Term] id: GO:0061156 name: pulmonary artery morphogenesis def: "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." [GOC:dph, GOC:yaf] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002012 ! results in morphogenesis of pulmonary artery relationship: RO:0002298 UBERON:0002012 ! results in morphogenesis of pulmonary artery created_by: dph creation_date: 2010-06-15T09:13:47Z [Term] id: GO:0061178 name: regulation of insulin secretion involved in cellular response to glucose stimulus def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:BHF, GOC:dph] synonym: "regulation of insulin secretion in response to glucose" EXACT [GOC:dph] is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035773 ! regulates insulin secretion involved in cellular response to glucose stimulus relationship: RO:0002211 GO:0035773 ! regulates insulin secretion involved in cellular response to glucose stimulus created_by: dph creation_date: 2010-07-13T09:38:42Z [Term] id: GO:0061179 name: negative regulation of insulin secretion involved in cellular response to glucose stimulus def: "Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:BHF, GOC:dph] synonym: "negative regulation of insulin secretion in response to glucose" RELATED [GOC:dph] synonym: "negative regulation of insulin secretion involved in cellular response to glucose" EXACT [GOC:bf] is_a: GO:0046676 ! negative regulation of insulin secretion is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0061178 ! regulation of insulin secretion involved in cellular response to glucose stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035773 ! negatively regulates insulin secretion involved in cellular response to glucose stimulus relationship: RO:0002212 GO:0035773 ! negatively regulates insulin secretion involved in cellular response to glucose stimulus created_by: dph creation_date: 2010-07-13T09:41:46Z [Term] id: GO:0061181 name: regulation of chondrocyte development def: "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002063 ! regulates chondrocyte development relationship: RO:0002211 GO:0002063 ! regulates chondrocyte development created_by: dph creation_date: 2010-07-14T08:28:52Z [Term] id: GO:0061182 name: negative regulation of chondrocyte development def: "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0032331 ! negative regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002063 ! negatively regulates chondrocyte development relationship: RO:0002212 GO:0002063 ! negatively regulates chondrocyte development created_by: dph creation_date: 2010-07-14T08:33:05Z [Term] id: GO:0061183 name: regulation of dermatome development def: "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061054 ! regulates dermatome development relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002211 GO:0061054 ! regulates dermatome development created_by: dph creation_date: 2010-07-14T08:40:26Z [Term] id: GO:0061184 name: positive regulation of dermatome development def: "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0040019 ! positive regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061054 ! positively regulates dermatome development relationship: RO:0002213 GO:0061054 ! positively regulates dermatome development created_by: dph creation_date: 2010-07-14T08:42:03Z [Term] id: GO:0061185 name: negative regulation of dermatome development def: "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0045992 ! negative regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061054 ! negatively regulates dermatome development relationship: RO:0002212 GO:0061054 ! negatively regulates dermatome development created_by: dph creation_date: 2010-07-14T08:43:08Z [Term] id: GO:0061189 name: positive regulation of sclerotome development def: "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:BHF, GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0061190 ! regulation of sclerotome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061056 ! positively regulates sclerotome development relationship: RO:0002213 GO:0061056 ! positively regulates sclerotome development created_by: dph creation_date: 2010-07-14T09:17:23Z [Term] id: GO:0061190 name: regulation of sclerotome development def: "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061056 ! regulates sclerotome development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0061056 ! regulates sclerotome development created_by: dph creation_date: 2010-07-14T09:19:47Z [Term] id: GO:0061193 name: taste bud development def: "The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001727 ! results in development of taste bud relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043586 ! tongue development relationship: RO:0002296 UBERON:0001727 ! results in development of taste bud created_by: dph creation_date: 2010-07-27T10:55:08Z [Term] id: GO:0061194 name: taste bud morphogenesis def: "The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001727 ! results in morphogenesis of taste bud relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043587 ! tongue morphogenesis relationship: part_of GO:0061193 ! taste bud development relationship: RO:0002298 UBERON:0001727 ! results in morphogenesis of taste bud created_by: dph creation_date: 2010-07-27T11:01:31Z [Term] id: GO:0061195 name: taste bud formation def: "The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001727 ! results in formation of anatomical entity taste bud relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0061194 ! taste bud morphogenesis relationship: RO:0002297 UBERON:0001727 ! results in formation of anatomical entity taste bud created_by: dph creation_date: 2010-07-27T12:22:26Z [Term] id: GO:0061205 name: paramesonephric duct development def: "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." [GOC:dph, GOC:yaf] synonym: "Mullerian duct development" EXACT [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003890 ! results in development of Mullerian duct relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0003890 ! results in development of Mullerian duct created_by: dph creation_date: 2010-07-30T10:54:47Z [Term] id: GO:0061206 name: mesonephros morphogenesis def: "The process in which the anatomical structures of the mesonephros are generated and organized." [GOC:mtg_kidney_jan10] synonym: "Wolffian body morphogenesis" EXACT [GOC:dph] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000080 ! results in morphogenesis of mesonephros relationship: part_of GO:0001823 ! mesonephros development relationship: RO:0002298 UBERON:0000080 ! results in morphogenesis of mesonephros created_by: dph creation_date: 2010-08-17T03:11:10Z [Term] id: GO:0061208 name: cell differentiation involved in mesonephros development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:21:23Z [Term] id: GO:0061209 name: cell proliferation involved in mesonephros development def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:22:46Z [Term] id: GO:0061210 name: cell-cell signaling involved in mesonephros development def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in mesonephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:24:08Z [Term] id: GO:0061211 name: mesonephric collecting duct development def: "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005319 ! results in development of mesonephric collecting duct relationship: part_of GO:0001823 ! mesonephros development relationship: RO:0002296 UBERON:0005319 ! results in development of mesonephric collecting duct created_by: dph creation_date: 2010-08-17T03:25:51Z [Term] id: GO:0061213 name: positive regulation of mesonephros development def: "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001823 ! positively regulates mesonephros development relationship: RO:0002213 GO:0001823 ! positively regulates mesonephros development created_by: dph creation_date: 2010-08-17T03:39:35Z [Term] id: GO:0061214 name: mesonephric smooth muscle tissue development def: "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005321 ! results in development of mesonephric smooth muscle tissue relationship: part_of GO:0001823 ! mesonephros development relationship: RO:0002296 UBERON:0005321 ! results in development of mesonephric smooth muscle tissue created_by: dph creation_date: 2010-08-17T03:29:54Z [Term] id: GO:0061215 name: mesonephric nephron development def: "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005322 ! results in development of mesonephric nephron relationship: part_of GO:0001823 ! mesonephros development relationship: RO:0002296 UBERON:0005322 ! results in development of mesonephric nephron created_by: dph creation_date: 2010-08-17T03:31:08Z [Term] id: GO:0061217 name: regulation of mesonephros development def: "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001823 ! regulates mesonephros development relationship: RO:0002211 GO:0001823 ! regulates mesonephros development created_by: dph creation_date: 2010-08-17T03:35:31Z [Term] id: GO:0061218 name: negative regulation of mesonephros development def: "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001823 ! negatively regulates mesonephros development relationship: RO:0002212 GO:0001823 ! negatively regulates mesonephros development created_by: dph creation_date: 2010-08-17T03:43:06Z [Term] id: GO:0061219 name: mesonephric mesenchyme development def: "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005323 ! results in development of mesonephric mesenchyme relationship: part_of GO:0001823 ! mesonephros development relationship: RO:0002296 UBERON:0005323 ! results in development of mesonephric mesenchyme created_by: dph creation_date: 2010-08-17T03:45:44Z [Term] id: GO:0061221 name: mesonephric mesenchyme morphogenesis def: "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005323 ! results in morphogenesis of mesonephric mesenchyme relationship: part_of GO:0061219 ! mesonephric mesenchyme development relationship: RO:0002298 UBERON:0005323 ! results in morphogenesis of mesonephric mesenchyme created_by: dph creation_date: 2010-08-19T01:17:38Z [Term] id: GO:0061227 name: pattern specification involved in mesonephros development def: "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "mesonephros pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "mesonephros pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-19T02:22:22Z [Term] id: GO:0061228 name: mesonephric nephron morphogenesis def: "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005322 ! results in morphogenesis of mesonephric nephron relationship: part_of GO:0061206 ! mesonephros morphogenesis relationship: part_of GO:0061215 ! mesonephric nephron development relationship: RO:0002298 UBERON:0005322 ! results in morphogenesis of mesonephric nephron created_by: dph creation_date: 2010-08-19T02:26:24Z [Term] id: GO:0061235 name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis created_by: dph creation_date: 2010-08-19T02:57:11Z [Term] id: GO:0061241 name: mesonephric nephron epithelium development def: "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005330 ! results in development of mesonephric nephron epithelium relationship: part_of GO:0061215 ! mesonephric nephron development relationship: RO:0002296 UBERON:0005330 ! results in development of mesonephric nephron epithelium created_by: dph creation_date: 2010-08-19T03:11:59Z [Term] id: GO:0061243 name: mesonephric renal vesicle morphogenesis def: "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005331 ! results in morphogenesis of mesonephric renal vesicle relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis relationship: RO:0002298 UBERON:0005331 ! results in morphogenesis of mesonephric renal vesicle created_by: dph creation_date: 2010-08-19T03:20:21Z [Term] id: GO:0061261 name: mesenchymal to epithelial transition involved in mesonephros morphogenesis def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." [GOC:mtg_kidney_jan10] synonym: "mesonephric mesenchyme to epithelial transition" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0061208 ! cell differentiation involved in mesonephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0061206 ! mesonephros morphogenesis relationship: part_of GO:0061206 ! mesonephros morphogenesis created_by: dph creation_date: 2010-08-30T02:35:15Z [Term] id: GO:0061262 name: mesonephric renal vesicle formation def: "The developmental process pertaining to the initial formation of the mesonephros." [GOC:mtg_kidney_jan10] synonym: "mesonephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005331 ! results in formation of anatomical entity mesonephric renal vesicle relationship: part_of GO:0061243 ! mesonephric renal vesicle morphogenesis relationship: RO:0002297 UBERON:0005331 ! results in formation of anatomical entity mesonephric renal vesicle created_by: dph creation_date: 2010-08-30T02:41:20Z [Term] id: GO:0061271 name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0061262 ! mesonephric renal vesicle formation relationship: part_of GO:0061262 ! mesonephric renal vesicle formation created_by: dph creation_date: 2010-08-30T03:26:30Z [Term] id: GO:0061285 name: mesonephric capsule development def: "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006170 ! results in development of mesonephric capsule relationship: part_of GO:0001823 ! mesonephros development relationship: RO:0002296 UBERON:0006170 ! results in development of mesonephric capsule created_by: dph creation_date: 2010-09-02T01:50:06Z [Term] id: GO:0061286 name: mesonephric capsule morphogenesis def: "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0006170 ! results in morphogenesis of mesonephric capsule relationship: part_of GO:0061285 ! mesonephric capsule development relationship: RO:0002298 UBERON:0006170 ! results in morphogenesis of mesonephric capsule created_by: dph creation_date: 2010-09-02T01:53:31Z [Term] id: GO:0061287 name: mesonephric capsule formation def: "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0006170 ! results in formation of anatomical entity mesonephric capsule relationship: part_of GO:0061286 ! mesonephric capsule morphogenesis relationship: RO:0002297 UBERON:0006170 ! results in formation of anatomical entity mesonephric capsule created_by: dph creation_date: 2010-09-02T01:55:03Z [Term] id: GO:0061295 name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1901146 ! regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: RO:0002211 GO:0061235 ! regulates mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: RO:0002211 GO:1901146 ! regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:48:56Z [Term] id: GO:0061296 name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061218 ! negative regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1901146 ! negatively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: RO:0002212 GO:0061235 ! negatively regulates mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: RO:0002212 GO:1901146 ! negatively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:54:49Z [Term] id: GO:0061297 name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061213 ! positive regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1901146 ! positively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: RO:0002213 GO:0061235 ! positively regulates mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: RO:0002213 GO:1901146 ! positively regulates mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:58:59Z [Term] id: GO:0061298 name: retina vasculature development in camera-type eye def: "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] synonym: "retinal vasculature development" EXACT [GOC:dph] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004864 ! results in development of vasculature of retina relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: RO:0002296 UBERON:0004864 ! results in development of vasculature of retina created_by: dph creation_date: 2010-09-06T03:27:06Z [Term] id: GO:0061299 name: retina vasculature morphogenesis in camera-type eye def: "The process in which the vasculature of the retina is generated and organized." [GOC:BHF, GOC:dph] synonym: "retinal vasculature morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004864 ! results in morphogenesis of vasculature of retina relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061298 ! retina vasculature development in camera-type eye relationship: RO:0002298 UBERON:0004864 ! results in morphogenesis of vasculature of retina created_by: dph creation_date: 2010-09-06T03:28:25Z [Term] id: GO:0061303 name: cornea development in camera-type eye def: "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000964 ! results in development of cornea relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0043010 ! camera-type eye development relationship: RO:0002296 UBERON:0000964 ! results in development of cornea created_by: dph creation_date: 2010-09-14T02:09:08Z [Term] id: GO:0061304 name: retinal blood vessel morphogenesis def: "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] is_a: GO:0048514 ! blood vessel morphogenesis is_a: GO:0061299 ! retina vasculature morphogenesis in camera-type eye intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003501 ! results in morphogenesis of retina blood vessel relationship: RO:0002298 UBERON:0003501 ! results in morphogenesis of retina blood vessel created_by: dph creation_date: 2010-09-16T09:02:59Z [Term] id: GO:0061307 name: cardiac neural crest cell differentiation involved in heart development def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." [GOC:dph, GOC:mtg_heart, PMID:19705442] is_a: GO:0014033 ! neural crest cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0014033 ! neural crest cell differentiation intersection_of: part_of GO:0007507 ! heart development created_by: dph creation_date: 2010-09-23T08:50:56Z [Term] id: GO:0061308 name: cardiac neural crest cell development involved in heart development def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0014032 ! neural crest cell development intersection_of: GO:0014032 ! neural crest cell development intersection_of: part_of GO:0007507 ! heart development relationship: part_of GO:0061307 ! cardiac neural crest cell differentiation involved in heart development created_by: dph creation_date: 2010-09-23T09:01:49Z [Term] id: GO:0061309 name: cardiac neural crest cell development involved in outflow tract morphogenesis def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061308 ! cardiac neural crest cell development involved in heart development intersection_of: GO:0014032 ! neural crest cell development intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2010-09-23T09:08:37Z [Term] id: GO:0061323 name: cell proliferation involved in heart morphogenesis def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2010-09-28T09:05:26Z [Term] id: GO:0061325 name: cell proliferation involved in outflow tract morphogenesis def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2010-09-28T09:29:30Z [Term] id: GO:0061326 name: renal tubule development def: "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009773 ! results in development of renal tubule relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0072001 ! renal system development relationship: RO:0002296 UBERON:0009773 ! results in development of renal tubule created_by: dph creation_date: 2010-09-28T12:50:43Z [Term] id: GO:0061333 name: renal tubule morphogenesis def: "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0009773 ! results in morphogenesis of renal tubule relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0061326 ! renal tubule development relationship: RO:0002298 UBERON:0009773 ! results in morphogenesis of renal tubule created_by: dph creation_date: 2010-09-28T01:43:04Z [Term] id: GO:0061337 name: cardiac conduction def: "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." [GOC:dph] xref: Reactome:R-HSA-5576891 "Cardiac conduction" is_a: GO:0008016 ! regulation of heart contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2010-09-29T08:46:05Z [Term] id: GO:0061343 name: cell adhesion involved in heart morphogenesis def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0007155 ! cell adhesion intersection_of: GO:0007155 ! cell adhesion intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2010-09-29T11:34:06Z [Term] id: GO:0061344 name: regulation of cell adhesion involved in heart morphogenesis def: "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061343 ! regulates cell adhesion involved in heart morphogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0061343 ! regulates cell adhesion involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T11:35:27Z [Term] id: GO:0061351 name: neural precursor cell proliferation def: "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf] is_a: GO:0008283 ! cell population proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2010-10-01T11:06:04Z [Term] id: GO:0061383 name: trabecula morphogenesis def: "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000440 ! results in morphogenesis of trabecula relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002298 UBERON:0000440 ! results in morphogenesis of trabecula created_by: dph creation_date: 2010-12-02T08:51:45Z [Term] id: GO:0061384 name: heart trabecula morphogenesis def: "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0061383 ! trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002511 ! results in morphogenesis of trabecula carnea relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002298 UBERON:0002511 ! results in morphogenesis of trabecula carnea created_by: dph creation_date: 2010-12-02T08:54:20Z [Term] id: GO:0061385 name: fibroblast proliferation involved in heart morphogenesis def: "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph] is_a: GO:0048144 ! fibroblast proliferation is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0048144 ! fibroblast proliferation intersection_of: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2011-02-10T01:41:59Z [Term] id: GO:0061437 name: renal system vasculature development def: "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0001944 ! vasculature development relationship: part_of GO:0072001 ! renal system development created_by: dph creation_date: 2012-03-08T12:16:24Z [Term] id: GO:0061438 name: renal system vasculature morphogenesis def: "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061437 ! renal system vasculature development created_by: dph creation_date: 2012-03-08T12:21:56Z [Term] id: GO:0061439 name: kidney vasculature morphogenesis def: "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0006544 ! results in morphogenesis of kidney vasculature relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0061438 ! renal system vasculature morphogenesis relationship: part_of GO:0061440 ! kidney vasculature development relationship: RO:0002298 UBERON:0006544 ! results in morphogenesis of kidney vasculature created_by: dph creation_date: 2012-03-08T12:30:11Z [Term] id: GO:0061440 name: kidney vasculature development def: "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0061437 ! renal system vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006544 ! results in development of kidney vasculature relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0006544 ! results in development of kidney vasculature created_by: dph creation_date: 2012-03-08T12:39:09Z [Term] id: GO:0061441 name: renal artery morphogenesis def: "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." [GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001184 ! results in morphogenesis of renal artery relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0061439 ! kidney vasculature morphogenesis relationship: RO:0002298 UBERON:0001184 ! results in morphogenesis of renal artery created_by: dph creation_date: 2012-03-08T12:42:09Z [Term] id: GO:0061448 name: connective tissue development def: "The progression of a connective tissue over time, from its formation to the mature structure." [GOC:BHF] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002384 ! results in development of connective tissue relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0002384 ! results in development of connective tissue created_by: dph creation_date: 2012-03-22T12:53:41Z [Term] id: GO:0061450 name: trophoblast cell migration def: "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000351 ! results in movement of trophoblast cell relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of GO:0007566 ! embryo implantation relationship: RO:0002565 CL:0000351 ! results in movement of trophoblast cell created_by: dph creation_date: 2012-07-10T08:38:37Z [Term] id: GO:0061453 name: interstitial cell of Cajal differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." [GOC:dph] synonym: "ICC differentiation" RELATED [GOC:dph] is_a: GO:0060563 ! neuroepithelial cell differentiation is_a: GO:0060575 ! intestinal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0002088 ! results in acquisition of features of interstitial cell of Cajal relationship: RO:0002315 CL:0002088 ! results in acquisition of features of interstitial cell of Cajal created_by: dph creation_date: 2012-07-20T08:20:50Z [Term] id: GO:0061458 name: reproductive system development namespace: biological_process def: "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000990 ! results in development of reproductive system relationship: RO:0002296 UBERON:0000990 ! results in development of reproductive system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2012-08-22T17:47:53Z [Term] id: GO:0061469 name: regulation of type B pancreatic cell proliferation def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." [GOC:dph] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044342 ! regulates type B pancreatic cell proliferation relationship: RO:0002211 GO:0044342 ! regulates type B pancreatic cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2012-11-01T13:16:23Z [Term] id: GO:0061484 name: hematopoietic stem cell homeostasis def: "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." [GOC:dph, PMID:21508411] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell relationship: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2012-12-04T09:41:02Z [Term] id: GO:0061512 name: protein localization to cilium def: "A process in which a protein is transported to, or maintained in, a location within a cilium." [GOC:dph] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005929 ! has target end location cilium relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002339 GO:0005929 ! has target end location cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2013-03-22T15:41:44Z [Term] id: GO:0061515 name: myeloid cell development def: "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0030097 ! hemopoiesis intersection_of: GO:0048468 ! cell development intersection_of: RO:0002296 CL:0000763 ! results in development of myeloid cell relationship: part_of GO:0030099 ! myeloid cell differentiation relationship: RO:0002296 CL:0000763 ! results in development of myeloid cell created_by: dph creation_date: 2013-04-18T13:03:16Z [Term] id: GO:0061523 name: cilium disassembly def: "A cellular process that results in the breakdown of a cilium." [GOC:cilia, GOC:dph, PMID:17604723, PMID:27350441] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "cilium resorption" EXACT [GOC:dph] is_a: GO:0044782 ! cilium organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005929 ! results in disassembly of cilium relationship: RO:0002590 GO:0005929 ! results in disassembly of cilium created_by: dph creation_date: 2013-04-18T14:59:59Z [Term] id: GO:0061525 name: hindgut development def: "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." [GOC:dph] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001046 ! results in development of hindgut relationship: RO:0002296 UBERON:0001046 ! results in development of hindgut created_by: dph creation_date: 2013-06-14T11:22:21Z [Term] id: GO:0061526 name: acetylcholine secretion def: "The regulated release of acetylcholine by a cell." [GOC:dph] is_a: GO:0015870 ! acetylcholine transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine created_by: dph creation_date: 2013-06-21T15:40:39Z [Term] id: GO:0061533 name: norepinephrine secretion, neurotransmission def: "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." [GOC:dph] synonym: "noradrenaline secretion, neurotransmission" EXACT [GOC:dph] is_a: GO:0048243 ! norepinephrine secretion is_a: GO:0160043 ! catecholamine secretion, neurotransmission intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) created_by: dph creation_date: 2013-06-21T16:05:08Z [Term] id: GO:0061548 name: ganglion development def: "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "ganglia development" RELATED [GOC:dph] synonym: "gangliogenesis" NARROW [GOC:BHF, GOC:rl] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000045 ! results in development of ganglion relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007399 ! nervous system development relationship: RO:0002296 UBERON:0000045 ! results in development of ganglion created_by: dph creation_date: 2013-07-10T08:36:12Z [Term] id: GO:0061549 name: sympathetic ganglion development def: "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." [GOC:BHF, GOC:rl] synonym: "sympathetic ganglia development" RELATED [GOC:dph] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001806 ! results in development of sympathetic ganglion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048485 ! sympathetic nervous system development relationship: RO:0002296 UBERON:0001806 ! results in development of sympathetic ganglion created_by: dph creation_date: 2013-07-10T08:38:01Z [Term] id: GO:0061550 name: cranial ganglion development def: "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "cranial ganglia development" RELATED [GOC:dph] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001714 ! results in development of cranial ganglion relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021545 ! cranial nerve development relationship: RO:0002296 UBERON:0001714 ! results in development of cranial ganglion created_by: dph creation_date: 2013-07-10T08:40:14Z [Term] id: GO:0061551 name: trigeminal ganglion development def: "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "trigeminal ganglia development" RELATED [GOC:dph] is_a: GO:0061550 ! cranial ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001675 ! results in development of trigeminal ganglion relationship: RO:0002296 UBERON:0001675 ! results in development of trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:42:19Z [Term] id: GO:0061552 name: ganglion morphogenesis def: "The process in which the anatomical structures of ganglion are generated and organized." [GOC:dph] synonym: "ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000045 ! results in morphogenesis of ganglion relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0061548 ! ganglion development relationship: RO:0002298 UBERON:0000045 ! results in morphogenesis of ganglion created_by: dph creation_date: 2013-07-10T08:44:57Z [Term] id: GO:0061553 name: ganglion maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." [GOC:dph] synonym: "ganglia maturation" RELATED [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0000045 ! results in maturation of ganglion relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0061548 ! ganglion development relationship: RO:0002299 UBERON:0000045 ! results in maturation of ganglion created_by: dph creation_date: 2013-07-10T08:45:59Z [Term] id: GO:0061554 name: ganglion formation def: "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "ganglia formation" RELATED [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000045 ! results in formation of anatomical entity ganglion relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0061552 ! ganglion morphogenesis relationship: RO:0002297 UBERON:0000045 ! results in formation of anatomical entity ganglion created_by: dph creation_date: 2013-07-10T08:51:50Z [Term] id: GO:0061556 name: trigeminal ganglion morphogenesis def: "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." [GOC:dph] synonym: "trigeminal ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0061559 ! cranial ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001675 ! results in morphogenesis of trigeminal ganglion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis relationship: part_of GO:0061551 ! trigeminal ganglion development relationship: RO:0002298 UBERON:0001675 ! results in morphogenesis of trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:57:12Z [Term] id: GO:0061557 name: trigeminal ganglion maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." [GOC:dph] synonym: "trigeminal ganglia maturation" RELATED [GOC:dph] is_a: GO:0061558 ! cranial ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0001675 ! results in maturation of trigeminal ganglion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0021635 ! trigeminal nerve maturation relationship: part_of GO:0061551 ! trigeminal ganglion development relationship: RO:0002299 UBERON:0001675 ! results in maturation of trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:58:24Z [Term] id: GO:0061558 name: cranial ganglion maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." [GOC:dph] synonym: "cranial ganglia maturation" RELATED [GOC:dph] is_a: GO:0061553 ! ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: RO:0002299 UBERON:0001714 ! results in maturation of cranial ganglion relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021605 ! cranial nerve maturation relationship: part_of GO:0061550 ! cranial ganglion development relationship: RO:0002299 UBERON:0001714 ! results in maturation of cranial ganglion created_by: dph creation_date: 2013-07-10T08:59:52Z [Term] id: GO:0061559 name: cranial ganglion morphogenesis def: "The process in which the anatomical structure of a cranial ganglion is generated and organized." [GOC:dph] synonym: "cranial ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0061552 ! ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001714 ! results in morphogenesis of cranial ganglion relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0021602 ! cranial nerve morphogenesis relationship: part_of GO:0061550 ! cranial ganglion development relationship: RO:0002298 UBERON:0001714 ! results in morphogenesis of cranial ganglion created_by: dph creation_date: 2013-07-10T09:02:15Z [Term] id: GO:0061560 name: cranial ganglion formation def: "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "cranial ganglia formation" RELATED [GOC:dph] is_a: GO:0061554 ! ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001714 ! results in formation of anatomical entity cranial ganglion relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0061559 ! cranial ganglion morphogenesis relationship: RO:0002297 UBERON:0001714 ! results in formation of anatomical entity cranial ganglion created_by: dph creation_date: 2013-07-10T09:07:27Z [Term] id: GO:0061561 name: trigeminal ganglion formation def: "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "trigeminal ganglia formation" RELATED [GOC:dph] is_a: GO:0061560 ! cranial ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001675 ! results in formation of anatomical entity trigeminal ganglion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061556 ! trigeminal ganglion morphogenesis relationship: RO:0002297 UBERON:0001675 ! results in formation of anatomical entity trigeminal ganglion created_by: dph creation_date: 2013-07-10T09:08:13Z [Term] id: GO:0061564 name: axon development def: "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." [GOC:dph, GOC:pg, GOC:pr] is_a: GO:0031175 ! neuron projection development created_by: dph creation_date: 2013-07-18T14:43:01Z [Term] id: GO:0061572 name: actin filament bundle organization def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." [GOC:dph] synonym: "actin filament cable organization" RELATED [GOC:dph] is_a: GO:0007015 ! actin filament organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0032432 ! results in organization of actin filament bundle relationship: RO:0002592 GO:0032432 ! results in organization of actin filament bundle created_by: dph creation_date: 2013-08-02T11:24:11Z [Term] id: GO:0061580 name: colon epithelial cell migration def: "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0061582 ! intestinal epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0011108 ! results in movement of colon epithelial cell relationship: RO:0002565 CL:0011108 ! results in movement of colon epithelial cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4890 created_by: dph creation_date: 2013-12-23T07:26:54Z [Term] id: GO:0061581 name: corneal epithelial cell migration def: "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000575 ! results in movement of corneal epithelial cell relationship: RO:0002565 CL:0000575 ! results in movement of corneal epithelial cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4890 created_by: dph creation_date: 2013-12-23T07:28:29Z [Term] id: GO:0061582 name: intestinal epithelial cell migration def: "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0002563 ! results in movement of intestinal epithelial cell relationship: RO:0002565 CL:0002563 ! results in movement of intestinal epithelial cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4890 created_by: dph creation_date: 2013-12-23T07:30:55Z [Term] id: GO:0061626 name: pharyngeal arch artery morphogenesis def: "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." [GOC:BHF, GOC:dph, PMID:20122914] synonym: "aortic arch artery morphogenesis" BROAD [GOC:dph] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004363 ! results in morphogenesis of pharyngeal arch artery relationship: part_of GO:0060037 ! pharyngeal system development relationship: RO:0002298 UBERON:0004363 ! results in morphogenesis of pharyngeal arch artery created_by: dph creation_date: 2014-05-09T15:34:06Z [Term] id: GO:0061682 name: seminal vesicle morphogenesis def: "The process in which the anatomical structures of a seminal vesicle are generated and organized." [GOC:dph] is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000998 ! results in morphogenesis of seminal vesicle relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0061107 ! seminal vesicle development relationship: RO:0002298 UBERON:0000998 ! results in morphogenesis of seminal vesicle created_by: dph creation_date: 2015-03-04T13:33:49Z [Term] id: GO:0061683 name: branching involved in seminal vesicle morphogenesis def: "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph, PMID:16916376] synonym: "gonecyst branching morphogenesis" EXACT [GOC:dph] synonym: "seminal gland branching morphogenesis" EXACT [GOC:dph] synonym: "seminal vesicle branching" EXACT [GOC:dph] synonym: "seminal vesicle branching morphogenesis" EXACT [GOC:dph] is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0061682 ! seminal vesicle morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0061108 ! seminal vesicle epithelium development relationship: part_of GO:0061682 ! seminal vesicle morphogenesis created_by: dph creation_date: 2015-03-04T13:39:47Z [Term] id: GO:0061687 name: detoxification of inorganic compound def: "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity relationship: RO:0004009 CHEBI:24835 ! has primary input inorganic molecular entity created_by: dph creation_date: 2015-03-09T09:16:23Z [Term] id: GO:0061725 name: cytosolic lipolysis def: "The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases." [GOC:autophagy] is_a: GO:0016042 ! lipid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0005829 ! occurs in cytosol intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: BFO:0000066 GO:0005829 ! occurs in cytosol property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI created_by: dph creation_date: 2015-07-08T13:42:15Z [Term] id: GO:0061792 name: secretory granule maturation def: "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling." [GOC:bf, GOC:dph, GOC:PARL, PMID:16618809] is_a: GO:0033363 ! secretory granule organization is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 GO:0030141 ! results in maturation of secretory granule relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002299 GO:0030141 ! results in maturation of secretory granule property_value: RO:0002161 NCBITaxon:4890 created_by: dph creation_date: 2016-09-09T13:24:34Z [Term] id: GO:0061853 name: regulation of neuroblast migration def: "Any process that modulates the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097402 ! regulates neuroblast migration relationship: RO:0002211 GO:0097402 ! regulates neuroblast migration property_value: RO:0002161 NCBITaxon:451864 created_by: dph creation_date: 2017-03-08T18:17:07Z [Term] id: GO:0061854 name: positive regulation of neuroblast migration def: "Any process that activates or increases the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097402 ! positively regulates neuroblast migration relationship: RO:0002213 GO:0097402 ! positively regulates neuroblast migration property_value: RO:0002161 NCBITaxon:451864 created_by: dph creation_date: 2017-03-08T18:22:30Z [Term] id: GO:0061855 name: negative regulation of neuroblast migration def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097402 ! negatively regulates neuroblast migration relationship: RO:0002212 GO:0097402 ! negatively regulates neuroblast migration property_value: RO:0002161 NCBITaxon:451864 created_by: dph creation_date: 2017-03-08T18:26:21Z [Term] id: GO:0061900 name: glial cell activation def: "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:aruk, GOC:bc, PMID:18723082] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000125 ! has primary input glial cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0150076 ! neuroinflammatory response relationship: RO:0004009 CL:0000125 ! has primary input glial cell created_by: dph creation_date: 2017-06-13T13:06:23Z [Term] id: GO:0061938 name: protein localization to somatodendritic compartment def: "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." [PMID:18341993] synonym: "somatodendritic protein localization" EXACT [] is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0036477 ! has target end location somatodendritic compartment relationship: RO:0002339 GO:0036477 ! has target end location somatodendritic compartment created_by: dph creation_date: 2017-09-08T13:22:26Z [Term] id: GO:0061951 name: establishment of protein localization to plasma membrane def: "The directed movement of a protein to a specific location in a plasma membrane." [GOC:dph, GOC:vw] is_a: GO:0090150 ! establishment of protein localization to membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane relationship: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure relationship: RO:0002339 GO:0005886 ! has target end location plasma membrane created_by: dph creation_date: 2017-10-26T12:55:15Z [Term] id: GO:0061971 name: replacement bone morphogenesis def: "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." [PMID:29852585] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0012075 ! results in morphogenesis of replacement bone relationship: RO:0002298 UBERON:0012075 ! results in morphogenesis of replacement bone created_by: dph creation_date: 2018-02-12T18:10:59Z [Term] id: GO:0061972 name: dermal bone morphogenesis def: "The process in which bone which forms superficially in the organism are generated and organized." [PMID:12588850, PMID:15003632] is_a: GO:0061973 ! membrane bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0008907 ! results in morphogenesis of dermal bone relationship: RO:0002298 UBERON:0008907 ! results in morphogenesis of dermal bone created_by: dph creation_date: 2018-02-12T18:16:21Z [Term] id: GO:0061973 name: membrane bone morphogenesis def: "The process in which bone which forms deep in the organism are generated and organized." [PMID:14579374] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0002298 UBERON:0007842 ! results in morphogenesis of membrane bone relationship: RO:0002298 UBERON:0007842 ! results in morphogenesis of membrane bone created_by: dph creation_date: 2018-02-12T18:21:09Z [Term] id: GO:0061983 name: meiosis II cell cycle process def: "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." [PMID:29385397] synonym: "second meiotic division" EXACT [PMID:29385397] is_a: GO:1903046 ! meiotic cell cycle process created_by: dph creation_date: 2018-02-14T22:37:44Z [Term] id: GO:0062009 name: secondary palate development def: "The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences." [PMID:28784960] is_a: GO:0060021 ! roof of mouth development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001716 ! results in development of secondary palate relationship: in_taxon NCBITaxon:32524 ! Amniota relationship: RO:0002296 UBERON:0001716 ! results in development of secondary palate created_by: dph creation_date: 2018-02-26T22:55:20Z [Term] id: GO:0062012 name: regulation of small molecule metabolic process def: "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." [GOC:vw] synonym: "regulation of small molecule metabolism" EXACT [] xref: Reactome:R-HSA-9861718 "Regulation of pyruvate metabolism" is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044281 ! regulates small molecule metabolic process relationship: RO:0002211 GO:0044281 ! regulates small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:11:54Z [Term] id: GO:0062013 name: positive regulation of small molecule metabolic process def: "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "positive regulation of small molecule metabolism" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044281 ! positively regulates small molecule metabolic process relationship: RO:0002213 GO:0044281 ! positively regulates small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:25:10Z [Term] id: GO:0062014 name: negative regulation of small molecule metabolic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "negative regulation of small molecule metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044281 ! negatively regulates small molecule metabolic process relationship: RO:0002212 GO:0044281 ! negatively regulates small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:27:23Z [Term] id: GO:0062033 name: positive regulation of mitotic sister chromatid segregation def: "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." [PMID:12773390] is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation is_a: GO:0051984 ! positive regulation of chromosome segregation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0000070 ! positively regulates mitotic sister chromatid segregation relationship: RO:0002213 GO:0000070 ! positively regulates mitotic sister chromatid segregation created_by: dph creation_date: 2018-04-23T14:32:23Z [Term] id: GO:0062094 name: stomach development def: "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ." [PMID:11967278] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000945 ! results in development of stomach relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0048565 ! digestive tract development relationship: RO:0002296 UBERON:0000945 ! results in development of stomach created_by: dph creation_date: 2018-11-20T18:15:45Z [Term] id: GO:0062149 name: detection of stimulus involved in sensory perception of pain def: "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal." [PMID:19837031] is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0051606 ! detection of stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain relationship: part_of GO:0019233 ! sensory perception of pain created_by: dph creation_date: 2019-09-13T13:48:47Z [Term] id: GO:0062237 name: protein localization to postsynapse def: "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." [PMID:31189538] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0098794 ! has target end location postsynapse relationship: RO:0002339 GO:0098794 ! has target end location postsynapse created_by: dph creation_date: 2020-04-20T13:58:43Z [Term] id: GO:0065002 name: intracellular protein transmembrane transport def: "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." [GOC:isa_complete] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "intracellular membrane translocation of a protein" EXACT [] synonym: "intracellular protein membrane transport" EXACT [] synonym: "intracellular protein transport across a membrane" EXACT [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0071806 ! protein transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: BFO:0000066 GO:0005622 ! occurs in intracellular anatomical structure intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0065003 name: protein-containing complex assembly alt_id: GO:0006461 alt_id: GO:0034622 alt_id: GO:0043623 def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." [GOC:jl] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] synonym: "chaperone activity" RELATED [] synonym: "macromolecular complex assembly" RELATED [] synonym: "macromolecule complex assembly" RELATED [] synonym: "protein complex assembly" RELATED [] synonym: "protein complex formation" RELATED [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0032991 ! results in assembly of protein-containing complex relationship: RO:0002588 GO:0032991 ! results in assembly of protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI [Term] id: GO:0065007 name: biological regulation namespace: biological_process def: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "regulation" BROAD [] is_a: GO:0008150 ! biological process [Term] id: GO:0065008 name: regulation of biological quality namespace: biological_process def: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "regulation of biological attribute" EXACT [] synonym: "regulation of biological characteristic" EXACT [] is_a: GO:0065007 ! biological regulation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30599" xsd:anyURI [Term] id: GO:0065009 name: regulation of molecular function def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete] subset: gocheck_obsoletion_candidate subset: goslim_pir subset: goslim_plant synonym: "regulation of a molecular function" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003674 ! regulates molecular_function relationship: RO:0002211 GO:0003674 ! regulates molecular_function [Term] id: GO:0065010 name: extracellular membrane-bounded organelle def: "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete] synonym: "extracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: part_of GO:0005576 ! extracellular region [Term] id: GO:0070013 name: intracellular organelle lumen def: "An organelle lumen that is part of an intracellular organelle." [GOC:mah] is_a: GO:0043233 ! organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0043229 ! intracellular organelle relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0043229 ! intracellular organelle [Term] id: GO:0070050 name: neuron cellular homeostasis def: "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." [GOC:BHF, GOC:mah] synonym: "neuron maintenance" EXACT [] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: BFO:0000066 CL:0000540 ! occurs in neuron relationship: BFO:0000066 CL:0000540 ! occurs in neuron property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI [Term] id: GO:0070062 name: extracellular exosome def: "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] synonym: "exosome" EXACT [GOC:pr] synonym: "extracellular vesicular exosome" EXACT [GOC:vesicles] is_a: GO:1903561 ! extracellular vesicle relationship: part_of GO:0005615 ! extracellular space property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0070091 name: glucagon secretion def: "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:5391 ! has primary input glucagon relationship: RO:0004009 CHEBI:5391 ! has primary input glucagon [Term] id: GO:0070092 name: regulation of glucagon secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070091 ! regulates glucagon secretion relationship: RO:0002211 GO:0070091 ! regulates glucagon secretion [Term] id: GO:0070093 name: negative regulation of glucagon secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "down regulation of glucagon secretion" EXACT [] synonym: "down-regulation of glucagon secretion" EXACT [] synonym: "downregulation of glucagon secretion" EXACT [] synonym: "inhibition of glucagon secretion" NARROW [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070091 ! negatively regulates glucagon secretion relationship: RO:0002212 GO:0070091 ! negatively regulates glucagon secretion [Term] id: GO:0070094 name: positive regulation of glucagon secretion def: "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "activation of glucagon secretion" NARROW [] synonym: "stimulation of glucagon secretion" NARROW [] synonym: "up regulation of glucagon secretion" EXACT [] synonym: "up-regulation of glucagon secretion" EXACT [] synonym: "upregulation of glucagon secretion" EXACT [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070091 ! positively regulates glucagon secretion relationship: RO:0002213 GO:0070091 ! positively regulates glucagon secretion [Term] id: GO:0070161 name: anchoring junction def: "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." [ISBN:0815332181] synonym: "anchoring cell junction" EXACT [GOC:mah] is_a: GO:0030054 ! cell junction property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0070192 name: chromosome organization involved in meiotic cell cycle def: "A process of chromosome organization that is involved in a meiotic cell cycle." [GOC:mah] synonym: "chromosome organisation involved in meiosis" EXACT [GOC:mah] synonym: "meiotic chromosome organization" EXACT [GOC:mah] is_a: GO:0051276 ! chromosome organization is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051276 ! chromosome organization intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0070199 name: establishment of protein localization to chromosome def: "The directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0005694 ! has target end location chromosome relationship: RO:0002339 GO:0005694 ! has target end location chromosome [Term] id: GO:0070201 name: regulation of establishment of protein localization def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation" EXACT [GOC:mah] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0045184 ! regulates establishment of protein localization relationship: RO:0002211 GO:0045184 ! regulates establishment of protein localization [Term] id: GO:0070202 name: regulation of establishment of protein localization to chromosome def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070199 ! regulates establishment of protein localization to chromosome relationship: RO:0002211 GO:0070199 ! regulates establishment of protein localization to chromosome [Term] id: GO:0070227 name: lymphocyte apoptotic process def: "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "lymphocyte apoptosis" NARROW [] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000542 ! occurs in lymphocyte relationship: BFO:0000066 CL:0000542 ! occurs in lymphocyte [Term] id: GO:0070228 name: regulation of lymphocyte apoptotic process def: "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "regulation of lymphocyte apoptosis" NARROW [] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070227 ! regulates lymphocyte apoptotic process relationship: RO:0002211 GO:0070227 ! regulates lymphocyte apoptotic process [Term] id: GO:0070229 name: negative regulation of lymphocyte apoptotic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "down regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "down-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "downregulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "inhibition of lymphocyte apoptosis" NARROW [GOC:add] synonym: "negative regulation of lymphocyte apoptosis" NARROW [] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070227 ! negatively regulates lymphocyte apoptotic process relationship: RO:0002212 GO:0070227 ! negatively regulates lymphocyte apoptotic process [Term] id: GO:0070230 name: positive regulation of lymphocyte apoptotic process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "activation of lymphocyte apoptosis" NARROW [GOC:add] synonym: "positive regulation of lymphocyte apoptosis" NARROW [] synonym: "stimulation of lymphocyte apoptosis" NARROW [GOC:add] synonym: "up regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "up-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "upregulation of lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070227 ! positively regulates lymphocyte apoptotic process relationship: RO:0002213 GO:0070227 ! positively regulates lymphocyte apoptotic process [Term] id: GO:0070231 name: T cell apoptotic process def: "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "T cell apoptosis" NARROW [] synonym: "T lymphocyte apoptosis" EXACT [GOC:add] synonym: "T-cell apoptosis" EXACT [GOC:add] synonym: "T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070227 ! lymphocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000084 ! occurs in T cell relationship: BFO:0000066 CL:0000084 ! occurs in T cell [Term] id: GO:0070232 name: regulation of T cell apoptotic process def: "Any process that modulates the occurrence or rate of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "regulation of T cell apoptosis" NARROW [] synonym: "regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070231 ! regulates T cell apoptotic process relationship: RO:0002211 GO:0070231 ! regulates T cell apoptotic process [Term] id: GO:0070233 name: negative regulation of T cell apoptotic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "down regulation of T cell apoptosis" EXACT [GOC:add] synonym: "down-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "downregulation of T cell apoptosis" EXACT [GOC:add] synonym: "inhibition of T cell apoptosis" NARROW [GOC:add] synonym: "negative regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "negative regulation of T cell apoptosis" NARROW [] synonym: "negative regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070231 ! negatively regulates T cell apoptotic process relationship: RO:0002212 GO:0070231 ! negatively regulates T cell apoptotic process [Term] id: GO:0070234 name: positive regulation of T cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "activation of T cell apoptosis" NARROW [GOC:add] synonym: "positive regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "positive regulation of T cell apoptosis" NARROW [] synonym: "positive regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-lymphocyte apoptosis" EXACT [GOC:add] synonym: "stimulation of T cell apoptosis" NARROW [GOC:add] synonym: "up regulation of T cell apoptosis" EXACT [GOC:add] synonym: "up-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "upregulation of T cell apoptosis" EXACT [GOC:add] is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070231 ! positively regulates T cell apoptotic process relationship: RO:0002213 GO:0070231 ! positively regulates T cell apoptotic process [Term] id: GO:0070253 name: somatostatin secretion def: "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 CHEBI:64628 ! has primary input somatostatin relationship: RO:0004009 CHEBI:64628 ! has primary input somatostatin [Term] id: GO:0070254 name: mucus secretion def: "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." [GOC:add, ISBN:068340007X, ISBN:0721662544] synonym: "mucus production" EXACT [GOC:add] is_a: GO:0007589 ! body fluid secretion is_a: GO:0032941 ! secretion by tissue intersection_of: GO:0046903 ! secretion intersection_of: RO:0004009 UBERON:0000912 ! has primary input mucus relationship: RO:0004009 UBERON:0000912 ! has primary input mucus property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0070255 name: regulation of mucus secretion def: "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "regulation of mucus production" EXACT [GOC:add] is_a: GO:0050878 ! regulation of body fluid levels is_a: GO:0051046 ! regulation of secretion is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070254 ! regulates mucus secretion relationship: RO:0002211 GO:0070254 ! regulates mucus secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0070256 name: negative regulation of mucus secretion def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "negative regulation of mucus production" EXACT [GOC:add] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070254 ! negatively regulates mucus secretion relationship: RO:0002212 GO:0070254 ! negatively regulates mucus secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0070257 name: positive regulation of mucus secretion def: "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "positive regulation of mucus production" EXACT [GOC:add] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070254 ! positively regulates mucus secretion relationship: RO:0002213 GO:0070254 ! positively regulates mucus secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0070278 name: extracellular matrix constituent secretion def: "The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell." [GOC:mah] synonym: "ECM constituent secretion" EXACT [GOC:mah] synonym: "ECM secretion" EXACT [GOC:mah] is_a: GO:0032940 ! secretion by cell relationship: part_of GO:0030198 ! extracellular matrix organization [Term] id: GO:0070285 name: pigment cell development def: "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." [GOC:cvs] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0000147 ! results in development of pigment cell relationship: part_of GO:0050931 ! pigment cell differentiation relationship: RO:0002296 CL:0000147 ! results in development of pigment cell [Term] id: GO:0070293 name: renal absorption def: "A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)." [GOC:dph, GOC:mah, GOC:yaf] synonym: "nephron absorption" EXACT [GOC:mah] synonym: "renal reabsorption" EXACT [GOC:dph] is_a: GO:0003014 ! renal system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0070295 name: renal water absorption def: "A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:dph, GOC:mah] synonym: "nephron water absorption" EXACT [GOC:mah] synonym: "renal water reabsorption" EXACT [GOC:dph] is_a: GO:0003097 ! renal water transport is_a: GO:0070293 ! renal absorption property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0070341 name: fat cell proliferation def: "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." [GOC:mah, GOC:sl] synonym: "adipocyte proliferation" EXACT [GOC:sl] synonym: "adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000136 ! acts on population of adipocyte relationship: RO:0012003 CL:0000136 ! acts on population of adipocyte property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0070344 name: regulation of fat cell proliferation def: "Any process that modulates the frequency, rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070341 ! regulates fat cell proliferation relationship: RO:0002211 GO:0070341 ! regulates fat cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0070345 name: negative regulation of fat cell proliferation def: "Any process that stops or decreases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "down regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "down-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "downregulation of fat cell proliferation" EXACT [GOC:mah] synonym: "inhibition of fat cell proliferation" NARROW [GOC:mah] synonym: "negative regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "negative regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070341 ! negatively regulates fat cell proliferation relationship: RO:0002212 GO:0070341 ! negatively regulates fat cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0070346 name: positive regulation of fat cell proliferation def: "Any process that activates or increases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "activation of fat cell proliferation" NARROW [GOC:mah] synonym: "positive regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "positive regulation of adipose cell proliferation" EXACT [GOC:sl] synonym: "stimulation of fat cell proliferation" NARROW [GOC:mah] synonym: "up regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "up-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "upregulation of fat cell proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070341 ! positively regulates fat cell proliferation relationship: RO:0002213 GO:0070341 ! positively regulates fat cell proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0070365 name: hepatocyte differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." [CL:0000182, PMID:7588884] synonym: "liver cell differentiation" EXACT [GOC:mah] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000182 ! results in acquisition of features of hepatocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001889 ! liver development relationship: RO:0002315 CL:0000182 ! results in acquisition of features of hepatocyte [Term] id: GO:0070366 name: regulation of hepatocyte differentiation def: "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070365 ! regulates hepatocyte differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0070365 ! regulates hepatocyte differentiation [Term] id: GO:0070367 name: negative regulation of hepatocyte differentiation def: "Any process that stops or decreases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "down regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "down-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "downregulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "inhibition of hepatocyte differentiation" NARROW [GOC:mah] synonym: "negative regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070365 ! negatively regulates hepatocyte differentiation relationship: RO:0002212 GO:0070365 ! negatively regulates hepatocyte differentiation [Term] id: GO:0070368 name: positive regulation of hepatocyte differentiation def: "Any process that activates or increases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "activation of hepatocyte differentiation" NARROW [GOC:mah] synonym: "positive regulation of liver cell differentiation" EXACT [GOC:sl] synonym: "stimulation of hepatocyte differentiation" NARROW [GOC:mah] synonym: "up regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "up-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "upregulation of hepatocyte differentiation" EXACT [GOC:mah] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070365 ! positively regulates hepatocyte differentiation relationship: RO:0002213 GO:0070365 ! positively regulates hepatocyte differentiation [Term] id: GO:0070382 name: exocytic vesicle def: "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah] synonym: "exocytic constitutive secretory pathway transport vesicle" EXACT [] synonym: "exocytotic vesicle" EXACT [GOC:kad] is_a: GO:0030133 ! transport vesicle is_a: GO:0099503 ! secretory vesicle intersection_of: GO:0030133 ! transport vesicle intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane [Term] id: GO:0070444 name: oligodendrocyte progenitor proliferation def: "The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system." [GOC:mah, GOC:sl, PMID:15504915] synonym: "oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0002453 ! acts on population of oligodendrocyte precursor cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0042063 ! gliogenesis relationship: RO:0012003 CL:0002453 ! acts on population of oligodendrocyte precursor cell [Term] id: GO:0070445 name: regulation of oligodendrocyte progenitor proliferation def: "Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] synonym: "regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070444 ! regulates oligodendrocyte progenitor proliferation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0070444 ! regulates oligodendrocyte progenitor proliferation [Term] id: GO:0070446 name: negative regulation of oligodendrocyte progenitor proliferation def: "Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] synonym: "negative regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0070445 ! regulation of oligodendrocyte progenitor proliferation is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070444 ! negatively regulates oligodendrocyte progenitor proliferation relationship: RO:0002212 GO:0070444 ! negatively regulates oligodendrocyte progenitor proliferation [Term] id: GO:0070447 name: positive regulation of oligodendrocyte progenitor proliferation def: "Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] synonym: "positive regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0070445 ! regulation of oligodendrocyte progenitor proliferation is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070444 ! positively regulates oligodendrocyte progenitor proliferation relationship: RO:0002213 GO:0070444 ! positively regulates oligodendrocyte progenitor proliferation [Term] id: GO:0070482 name: response to oxygen levels def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." [GOC:BHF, GOC:mah] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0070483 name: detection of hypoxia def: "The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:BHF, GOC:mah] synonym: "detection of reduced oxygen levels" EXACT [GOC:vk] is_a: GO:0001666 ! response to hypoxia is_a: GO:0003032 ! detection of oxygen [Term] id: GO:0070507 name: regulation of microtubule cytoskeleton organization def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] synonym: "regulation of microtubule cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of microtubule dynamics" EXACT [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0000226 ! regulates microtubule cytoskeleton organization relationship: RO:0002211 GO:0000226 ! regulates microtubule cytoskeleton organization [Term] id: GO:0070586 name: cell-cell adhesion involved in gastrulation def: "The attachment of one cell to another cell affecting gastrulation." [GOC:dsf, PMID:19091770] is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: part_of GO:0007369 ! gastrulation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007369 ! gastrulation created_by: mah creation_date: 2009-04-24T02:48:23Z [Term] id: GO:0070587 name: regulation of cell-cell adhesion involved in gastrulation def: "Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation." [GOC:dsf, PMID:19091770] is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070586 ! regulates cell-cell adhesion involved in gastrulation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0070586 ! regulates cell-cell adhesion involved in gastrulation created_by: mah creation_date: 2009-04-24T02:51:07Z [Term] id: GO:0070633 name: transepithelial transport def: "The directed movement of a substance from one side of an epithelium to the other." [GOC:mah, GOC:yaf, ISBN:0716731363] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002342 UBERON:0000483 ! results in transport across epithelium relationship: RO:0002342 UBERON:0000483 ! results in transport across epithelium created_by: mah creation_date: 2009-05-06T03:31:02Z [Term] id: GO:0070634 name: transepithelial ammonium transport def: "The directed movement of ammonium ions from one side of an epithelium to the other." [GOC:mah, GOC:yaf] is_a: GO:0070633 ! transepithelial transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0070633 ! transepithelial transport intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium created_by: mah creation_date: 2009-05-06T03:34:43Z [Term] id: GO:0070661 name: leukocyte proliferation def: "The expansion of a leukocyte population by cell division." [GOC:add] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000738 ! acts on population of leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0012003 CL:0000738 ! acts on population of leukocyte created_by: mah creation_date: 2009-05-28T05:25:28Z [Term] id: GO:0070663 name: regulation of leukocyte proliferation def: "Any process that modulates the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070661 ! regulates leukocyte proliferation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0070661 ! regulates leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:30:39Z [Term] id: GO:0070664 name: negative regulation of leukocyte proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "down regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "down-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "downregulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "inhibition of leukocyte proliferation" NARROW [GOC:mah] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070661 ! negatively regulates leukocyte proliferation relationship: RO:0002212 GO:0070661 ! negatively regulates leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:34:50Z [Term] id: GO:0070665 name: positive regulation of leukocyte proliferation def: "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "activation of leukocyte proliferation" NARROW [GOC:mah] synonym: "stimulation of leukocyte proliferation" NARROW [GOC:mah] synonym: "up regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "up-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "upregulation of leukocyte proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070661 ! positively regulates leukocyte proliferation relationship: RO:0002213 GO:0070661 ! positively regulates leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:36:46Z [Term] id: GO:0070828 name: heterochromatin organization def: "Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin." [GOC:mah] synonym: "heterochromatin organisation" EXACT [GOC:mah] is_a: GO:0006325 ! chromatin organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0000792 ! results in organization of heterochromatin relationship: RO:0002592 GO:0000792 ! results in organization of heterochromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26702" xsd:anyURI created_by: mah creation_date: 2009-07-23T04:12:48Z [Term] id: GO:0070831 name: basement membrane assembly def: "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." [GOC:mah] comment: Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer. is_a: GO:0071711 ! basement membrane organization is_a: GO:0085029 ! extracellular matrix assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0005604 ! results in assembly of basement membrane relationship: RO:0002588 GO:0005604 ! results in assembly of basement membrane created_by: mah creation_date: 2009-07-23T05:01:51Z [Term] id: GO:0070857 name: regulation of bile acid biosynthetic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "regulation of bile acid formation" EXACT [GOC:mah] synonym: "regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010565 ! regulation of ketone metabolic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006699 ! regulates bile acid biosynthetic process relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0006699 ! regulates bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:09:02Z [Term] id: GO:0070858 name: negative regulation of bile acid biosynthetic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "down regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "down-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "downregulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "inhibition of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "negative regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "negative regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "negative regulation of bile acid formation" EXACT [GOC:mah] synonym: "negative regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010894 ! negative regulation of steroid biosynthetic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006699 ! negatively regulates bile acid biosynthetic process relationship: RO:0002212 GO:0006699 ! negatively regulates bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:16:40Z [Term] id: GO:0070859 name: positive regulation of bile acid biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "activation of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "positive regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "positive regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "positive regulation of bile acid formation" EXACT [GOC:mah] synonym: "positive regulation of bile acid synthesis" EXACT [GOC:mah] synonym: "stimulation of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "up regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "up-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "upregulation of bile acid biosynthetic process" EXACT [GOC:mah] is_a: GO:0010893 ! positive regulation of steroid biosynthetic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006699 ! positively regulates bile acid biosynthetic process relationship: RO:0002213 GO:0006699 ! positively regulates bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:22:58Z [Term] id: GO:0070873 name: regulation of glycogen metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0005977 ! regulates glycogen metabolic process relationship: RO:0002211 GO:0005977 ! regulates glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:44:53Z [Term] id: GO:0070874 name: negative regulation of glycogen metabolic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "negative regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0005977 ! negatively regulates glycogen metabolic process relationship: RO:0002212 GO:0005977 ! negatively regulates glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:50:41Z [Term] id: GO:0070875 name: positive regulation of glycogen metabolic process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "positive regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0010907 ! positive regulation of glucose metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0005977 ! positively regulates glycogen metabolic process relationship: RO:0002213 GO:0005977 ! positively regulates glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:53:55Z [Term] id: GO:0070887 name: cellular response to chemical stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate is_a: GO:0042221 ! response to chemical is_a: GO:0051716 ! cellular response to stimulus created_by: mah creation_date: 2009-08-27T04:41:45Z [Term] id: GO:0070925 name: organelle assembly def: "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] subset: gocheck_do_not_annotate subset: goslim_yeast is_a: GO:0006996 ! organelle organization is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0043226 ! results in assembly of organelle relationship: RO:0002588 GO:0043226 ! results in assembly of organelle created_by: mah creation_date: 2009-09-15T03:00:51Z [Term] id: GO:0070977 name: bone maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." [GOC:dph, GOC:mah] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0001474 ! results in maturation of bone element relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060348 ! bone development relationship: RO:0002299 UBERON:0001474 ! results in maturation of bone element created_by: mah creation_date: 2009-10-05T04:35:31Z [Term] id: GO:0071166 name: ribonucleoprotein complex localization def: "Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell." [GOC:mah] synonym: "cellular ribonucleoprotein complex localization" EXACT [GOC:mah] synonym: "establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:mah] synonym: "ribonucleoprotein complex localisation" EXACT [GOC:mah] synonym: "RNP localization" EXACT [GOC:mah] is_a: GO:0051641 ! cellular localization created_by: mah creation_date: 2009-11-19T04:46:05Z [Term] id: GO:0071168 name: protein localization to chromatin def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0034502 ! protein localization to chromosome intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0000785 ! has target end location chromatin relationship: RO:0002339 GO:0000785 ! has target end location chromatin created_by: mah creation_date: 2009-11-20T11:51:20Z [Term] id: GO:0071169 name: establishment of protein localization to chromatin def: "The directed movement of a protein to a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "establishment of protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0070199 ! establishment of protein localization to chromosome intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0000785 ! has target end location chromatin relationship: RO:0002339 GO:0000785 ! has target end location chromatin created_by: mah creation_date: 2009-11-20T11:52:43Z [Term] id: GO:0071214 name: cellular response to abiotic stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "cellular response to abiotic stress" NARROW [GOC:mah] is_a: GO:0009628 ! response to abiotic stimulus is_a: GO:0104004 ! cellular response to environmental stimulus created_by: mah creation_date: 2009-12-03T01:02:11Z [Term] id: GO:0071229 name: cellular response to acid chemical def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:mah, Wikipedia:Acid] comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if a cell were responding to glutamate, then the response would be glutamate-specific; the cell is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0071468 'cellular response to acidic pH' instead. subset: gocheck_do_not_annotate synonym: "cellular response to acid" BROAD [] synonym: "cellular response to acid anion" RELATED [] synonym: "cellular response to oxoanion" RELATED [] is_a: GO:0001101 ! response to acid chemical is_a: GO:0070887 ! cellular response to chemical stimulus created_by: mah creation_date: 2009-12-03T02:07:23Z [Term] id: GO:0071230 name: cellular response to amino acid stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:mah] synonym: "cellular response to amino acid" EXACT [GOC:mah] is_a: GO:0043200 ! response to amino acid is_a: GO:0071229 ! cellular response to acid chemical intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion created_by: mah creation_date: 2009-12-03T02:08:11Z [Term] id: GO:0071242 name: cellular response to ammonium ion alt_id: GO:1903718 def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] synonym: "cellular response to ammonia" EXACT [] is_a: GO:0060359 ! response to ammonium ion is_a: GO:1901699 ! cellular response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium created_by: mah creation_date: 2009-12-03T02:39:40Z [Term] id: GO:0071248 name: cellular response to metal ion def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:mah] synonym: "cellular response to heavy metal" NARROW [GOC:mah] synonym: "cellular response to metal" EXACT [GOC:mah] is_a: GO:0010038 ! response to metal ion is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation created_by: mah creation_date: 2009-12-03T02:46:31Z [Term] id: GO:0071311 name: cellular response to acetate def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:mah] is_a: GO:0010034 ! response to acetate is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:30089 ! has primary input acetate created_by: mah creation_date: 2009-12-10T04:48:16Z [Term] id: GO:0071312 name: cellular response to alkaloid def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:mah] is_a: GO:0043279 ! response to alkaloid is_a: GO:1901699 ! cellular response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:22315 ! has primary input alkaloid created_by: mah creation_date: 2009-12-10T04:50:58Z [Term] id: GO:0071322 name: cellular response to carbohydrate stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:mah] is_a: GO:0009743 ! response to carbohydrate is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate created_by: mah creation_date: 2009-12-10T05:13:33Z [Term] id: GO:0071326 name: cellular response to monosaccharide stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] is_a: GO:0034284 ! response to monosaccharide is_a: GO:0071322 ! cellular response to carbohydrate stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:35381 ! has primary input monosaccharide created_by: mah creation_date: 2009-12-10T05:27:18Z [Term] id: GO:0071331 name: cellular response to hexose stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:mah] is_a: GO:0009746 ! response to hexose is_a: GO:0071326 ! cellular response to monosaccharide stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose created_by: mah creation_date: 2009-12-10T05:37:00Z [Term] id: GO:0071333 name: cellular response to glucose stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:mah] is_a: GO:0001678 ! intracellular glucose homeostasis is_a: GO:0009749 ! response to glucose is_a: GO:0071331 ! cellular response to hexose stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose created_by: mah creation_date: 2009-12-10T05:38:03Z [Term] id: GO:0071375 name: cellular response to peptide hormone stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [GOC:mah] synonym: "cellular response to polypeptide hormone stimulus" EXACT [GOC:mah] is_a: GO:0032870 ! cellular response to hormone stimulus is_a: GO:0043434 ! response to peptide hormone is_a: GO:1901699 ! cellular response to nitrogen compound is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:25905 ! has primary input peptide hormone property_value: RO:0002161 NCBITaxon:4751 created_by: mah creation_date: 2009-12-11T03:24:18Z [Term] id: GO:0071377 name: cellular response to glucagon stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:mah] xref: Reactome:R-HSA-163359 "Glucagon signaling in metabolic regulation" is_a: GO:0033762 ! response to glucagon is_a: GO:0071375 ! cellular response to peptide hormone stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:5391 ! has primary input glucagon property_value: RO:0002161 NCBITaxon:4751 created_by: mah creation_date: 2009-12-11T03:25:07Z [Term] id: GO:0071383 name: cellular response to steroid hormone stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:mah] xref: Reactome:R-HSA-3371497 "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" is_a: GO:0032870 ! cellular response to hormone stimulus is_a: GO:0048545 ! response to steroid hormone is_a: GO:0071396 ! cellular response to lipid intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:26764 ! has primary input steroid hormone property_value: RO:0002161 NCBITaxon:4751 created_by: mah creation_date: 2009-12-11T03:49:02Z [Term] id: GO:0071396 name: cellular response to lipid def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:mah] is_a: GO:0033993 ! response to lipid is_a: GO:0070887 ! cellular response to chemical stimulus intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid created_by: mah creation_date: 2009-12-11T04:37:10Z [Term] id: GO:0071418 name: cellular response to amine stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:mah] is_a: GO:0014075 ! response to amine is_a: GO:1901699 ! cellular response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:32952 ! has primary input amine created_by: mah creation_date: 2009-12-14T04:08:17Z [Term] id: GO:0071425 name: hematopoietic stem cell proliferation def: "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." [CL:0000037, GOC:add, GOC:BHF, GOC:mah, GOC:rl] synonym: "hemopoietic stem cell proliferation" EXACT [] is_a: GO:0072089 ! stem cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0030097 ! hemopoiesis relationship: RO:0012003 CL:0000037 ! acts on population of hematopoietic stem cell created_by: mah creation_date: 2009-12-16T10:22:52Z [Term] id: GO:0071462 name: cellular response to water stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." [GOC:mah] is_a: GO:0009415 ! response to water is_a: GO:0071214 ! cellular response to abiotic stimulus is_a: GO:0071229 ! cellular response to acid chemical is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:15377 ! has primary input water created_by: mah creation_date: 2009-12-18T11:32:44Z [Term] id: GO:0071495 name: cellular response to endogenous stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate xref: Reactome:R-HSA-9860931 "Response of endothelial cells to shear stress" is_a: GO:0009719 ! response to endogenous stimulus created_by: mah creation_date: 2009-12-18T02:25:40Z [Term] id: GO:0071599 name: otic vesicle development def: "The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:mah] is_a: GO:0007423 ! sensory organ development is_a: GO:0035295 ! tube development is_a: GO:0048839 ! inner ear development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003051 ! results in development of ear vesicle relationship: RO:0002296 UBERON:0003051 ! results in development of ear vesicle created_by: mah creation_date: 2010-02-04T04:07:17Z [Term] id: GO:0071600 name: otic vesicle morphogenesis def: "The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:mah] is_a: GO:0042472 ! inner ear morphogenesis is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003051 ! results in morphogenesis of ear vesicle relationship: part_of GO:0071599 ! otic vesicle development relationship: RO:0002298 UBERON:0003051 ! results in morphogenesis of ear vesicle created_by: mah creation_date: 2010-02-04T04:07:27Z [Term] id: GO:0071626 name: mastication def: "The process of biting and mashing food with the teeth prior to swallowing." [GOC:gvg] synonym: "chewing" EXACT [GOC:mah] is_a: GO:0022600 ! digestive system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mah creation_date: 2010-02-10T11:19:48Z [Term] id: GO:0071674 name: mononuclear cell migration def: "The movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000842 ! results in movement of mononuclear leukocyte relationship: RO:0002565 CL:0000842 ! results in movement of mononuclear leukocyte created_by: mah creation_date: 2010-02-16T02:11:00Z [Term] id: GO:0071675 name: regulation of mononuclear cell migration def: "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0002685 ! regulation of leukocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071674 ! regulates mononuclear cell migration relationship: RO:0002211 GO:0071674 ! regulates mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:11:53Z [Term] id: GO:0071676 name: negative regulation of mononuclear cell migration def: "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "down regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "down-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "downregulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "inhibition of mononuclear cell migration" NARROW [GOC:mah] is_a: GO:0002686 ! negative regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071674 ! negatively regulates mononuclear cell migration relationship: RO:0002212 GO:0071674 ! negatively regulates mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:13:55Z [Term] id: GO:0071677 name: positive regulation of mononuclear cell migration def: "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "activation of mononuclear cell migration" NARROW [GOC:mah] synonym: "stimulation of mononuclear cell migration" NARROW [GOC:mah] synonym: "up regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "up-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "upregulation of mononuclear cell migration" EXACT [GOC:mah] is_a: GO:0002687 ! positive regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071674 ! positively regulates mononuclear cell migration relationship: RO:0002213 GO:0071674 ! positively regulates mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:15:29Z [Term] id: GO:0071692 name: protein localization to extracellular region def: "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." [GOC:mah] synonym: "protein localisation in extracellular region" EXACT [GOC:mah] synonym: "protein localization in extracellular region" EXACT [] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0002339 GO:0005576 ! has target end location extracellular region relationship: RO:0004009 PR:000000001 ! has primary input protein created_by: mah creation_date: 2010-02-25T04:00:13Z [Term] id: GO:0071695 name: anatomical structure maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." [GOC:mah] is_a: GO:0021700 ! developmental maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0000061 ! results in maturation of anatomical structure relationship: part_of GO:0048856 ! anatomical structure development relationship: RO:0002299 UBERON:0000061 ! results in maturation of anatomical structure created_by: mah creation_date: 2010-03-02T11:43:38Z [Term] id: GO:0071696 name: ectodermal placode development def: "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005085 ! results in development of ectodermal placode relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0005085 ! results in development of ectodermal placode created_by: mah creation_date: 2010-03-02T11:48:01Z [Term] id: GO:0071697 name: ectodermal placode morphogenesis def: "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005085 ! results in morphogenesis of ectodermal placode relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0071696 ! ectodermal placode development relationship: RO:0002298 UBERON:0005085 ! results in morphogenesis of ectodermal placode created_by: mah creation_date: 2010-03-02T11:49:51Z [Term] id: GO:0071698 name: olfactory placode development def: "The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] is_a: GO:0071696 ! ectodermal placode development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003050 ! results in development of olfactory placode relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002296 UBERON:0003050 ! results in development of olfactory placode created_by: mah creation_date: 2010-03-02T12:45:14Z [Term] id: GO:0071699 name: olfactory placode morphogenesis def: "The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0071697 ! ectodermal placode morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003050 ! results in morphogenesis of olfactory placode relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0071698 ! olfactory placode development relationship: RO:0002298 UBERON:0003050 ! results in morphogenesis of olfactory placode created_by: mah creation_date: 2010-03-02T12:45:45Z [Term] id: GO:0071700 name: olfactory placode maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0003050 ! results in maturation of olfactory placode relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: part_of GO:0071698 ! olfactory placode development relationship: RO:0002299 UBERON:0003050 ! results in maturation of olfactory placode created_by: mah creation_date: 2010-03-02T01:10:54Z [Term] id: GO:0071705 name: nitrogen compound transport def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity relationship: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity created_by: mah creation_date: 2010-03-08T03:56:28Z [Term] id: GO:0071709 name: membrane assembly def: "The aggregation, arrangement and bonding together of a set of components to form a membrane." [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0016020 ! results in assembly of membrane relationship: part_of GO:0044091 ! membrane biogenesis relationship: RO:0002588 GO:0016020 ! results in assembly of membrane created_by: mah creation_date: 2010-03-10T11:19:17Z [Term] id: GO:0071711 name: basement membrane organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." [GOC:mah] comment: Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer. synonym: "basement membrane organisation" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005604 ! results in organization of basement membrane relationship: RO:0002592 GO:0005604 ! results in organization of basement membrane created_by: mah creation_date: 2010-03-10T11:57:10Z [Term] id: GO:0071763 name: nuclear membrane organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." [GOC:mah] synonym: "nuclear membrane organisation" EXACT [GOC:mah] synonym: "nuclear membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0031965 ! results in organization of nuclear membrane relationship: part_of GO:0006998 ! nuclear envelope organization relationship: RO:0002592 GO:0031965 ! results in organization of nuclear membrane created_by: mah creation_date: 2010-03-29T03:59:35Z [Term] id: GO:0071764 name: nuclear outer membrane organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." [GOC:mah] synonym: "nuclear outer membrane organisation" EXACT [GOC:mah] synonym: "nuclear outer membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0005640 ! results in organization of nuclear outer membrane relationship: RO:0002592 GO:0005640 ! results in organization of nuclear outer membrane created_by: mah creation_date: 2010-03-29T04:03:37Z [Term] id: GO:0071806 name: protein transmembrane transport def: "The process in which a protein is transported across a membrane." [GOC:mah, GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "protein membrane transport" EXACT [] is_a: GO:0015031 ! protein transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein created_by: mah creation_date: 2010-09-03T02:54:26Z [Term] id: GO:0071826 name: protein-RNA complex organization def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." [GOC:mah] synonym: "protein-RNA complex subunit organization" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organisation" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organization" EXACT [] synonym: "RNA-protein complex subunit organization" EXACT [GOC:mah] is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:1990904 ! results in organization of ribonucleoprotein complex relationship: RO:0002592 GO:1990904 ! results in organization of ribonucleoprotein complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI created_by: mah creation_date: 2010-09-08T10:10:35Z [Term] id: GO:0071840 name: cellular component organization or biogenesis alt_id: GO:0071841 def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate subset: goslim_flybase_ribbon subset: goslim_metagenomics synonym: "cellular component organisation or biogenesis" EXACT [GOC:mah] synonym: "cellular component organisation or biogenesis at cellular level" EXACT [GOC:mah] synonym: "cellular component organization or biogenesis at cellular level" EXACT [] is_a: GO:0009987 ! cellular process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI created_by: mah creation_date: 2010-09-10T01:39:16Z [Term] id: GO:0071867 name: response to monoamine def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] synonym: "response to monoamine stimulus" EXACT [GOC:dos] is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:63534 ! has primary input monoamine relationship: RO:0004009 CHEBI:63534 ! has primary input monoamine created_by: mah creation_date: 2010-09-13T02:36:37Z [Term] id: GO:0071868 name: cellular response to monoamine stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] is_a: GO:0071867 ! response to monoamine is_a: GO:1901699 ! cellular response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:63534 ! has primary input monoamine created_by: mah creation_date: 2010-09-13T02:38:52Z [Term] id: GO:0071869 name: response to catecholamine def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] synonym: "response to catecholamine stimulus" EXACT [GOC:dos] is_a: GO:0071867 ! response to monoamine is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0004009 CHEBI:33567 ! has primary input catecholamine created_by: mah creation_date: 2010-09-13T02:51:13Z [Term] id: GO:0071870 name: cellular response to catecholamine stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] is_a: GO:0071868 ! cellular response to monoamine stimulus is_a: GO:0071869 ! response to catecholamine is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine created_by: mah creation_date: 2010-09-13T02:54:50Z [Term] id: GO:0071873 name: response to norepinephrine def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "response to noradrenaline stimulus" EXACT [GOC:mah] synonym: "response to norepinephrine stimulus" EXACT [GOC:dos] is_a: GO:0071869 ! response to catecholamine intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) relationship: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) created_by: mah creation_date: 2010-09-13T03:31:53Z [Term] id: GO:0071874 name: cellular response to norepinephrine stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "cellular response to noradrenaline stimulus" EXACT [GOC:mah] is_a: GO:0071870 ! cellular response to catecholamine stimulus is_a: GO:0071873 ! response to norepinephrine intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:72587 ! has primary input (R)-noradrenaline(1+) created_by: mah creation_date: 2010-09-13T03:33:32Z [Term] id: GO:0071887 name: leukocyte apoptotic process def: "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "leukocyte apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000738 ! occurs in leukocyte relationship: BFO:0000066 CL:0000738 ! occurs in leukocyte relationship: in_taxon NCBITaxon:7742 ! Vertebrata created_by: mah creation_date: 2010-09-14T12:44:09Z [Term] id: GO:0071895 name: odontoblast differentiation def: "The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin." [GOC:sl, PMID:20425127] is_a: GO:0060563 ! neuroepithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000060 ! results in acquisition of features of odontoblast relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002315 CL:0000060 ! results in acquisition of features of odontoblast created_by: mah creation_date: 2010-09-14T04:00:40Z [Term] id: GO:0071944 name: cell periphery def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical structure created_by: mah creation_date: 2010-10-04T01:51:47Z [Term] id: GO:0071953 name: elastic fiber def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620] synonym: "elastic fibre" EXACT [GOC:mah] synonym: "elastin fiber" EXACT [GOC:BHF] is_a: GO:0099512 ! supramolecular fiber relationship: part_of GO:0031012 ! extracellular matrix created_by: mah creation_date: 2010-10-11T11:44:57Z [Term] id: GO:0071971 name: extracellular exosome assembly def: "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." [GOC:mah, GOC:tfm, PMID:19442504, PMID:27462458] synonym: "extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:0016050 ! vesicle organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0070062 ! results in assembly of extracellular exosome relationship: part_of GO:0097734 ! extracellular exosome biogenesis relationship: RO:0002588 GO:0070062 ! results in assembly of extracellular exosome property_value: RO:0002161 NCBITaxon:4890 created_by: mah creation_date: 2010-10-18T03:44:18Z [Term] id: GO:0072001 name: renal system development def: "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:6996269] subset: gocheck_do_not_annotate synonym: "urinary system development" BROAD [GOC:yaf] synonym: "urinary tract development" BROAD [GOC:yaf, PMID:17881463] is_a: GO:0048731 ! system development intersection_of: GO:0048731 ! system development intersection_of: RO:0002296 UBERON:0001008 ! results in development of renal system relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0001008 ! results in development of renal system created_by: mah creation_date: 2010-01-25T10:31:00Z [Term] id: GO:0072003 name: kidney rudiment formation def: "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] synonym: "kidney anlage formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005095 ! results in formation of anatomical entity kidney rudiment relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060993 ! kidney morphogenesis relationship: RO:0002297 UBERON:0005095 ! results in formation of anatomical entity kidney rudiment created_by: mah creation_date: 2010-01-25T11:18:58Z [Term] id: GO:0072006 name: nephron development def: "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] synonym: "nephrogenesis" RELATED [GOC:rph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001285 ! results in development of nephron relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0001285 ! results in development of nephron created_by: mah creation_date: 2010-01-25T01:37:16Z [Term] id: GO:0072009 name: nephron epithelium development def: "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004211 ! results in development of nephron epithelium relationship: part_of GO:0072006 ! nephron development relationship: RO:0002296 UBERON:0004211 ! results in development of nephron epithelium created_by: mah creation_date: 2010-01-25T02:01:39Z [Term] id: GO:0072028 name: nephron morphogenesis def: "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001285 ! results in morphogenesis of nephron relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0060993 ! kidney morphogenesis relationship: part_of GO:0072006 ! nephron development relationship: RO:0002298 UBERON:0001285 ! results in morphogenesis of nephron created_by: mah creation_date: 2010-01-25T02:45:52Z [Term] id: GO:0072033 name: renal vesicle formation def: "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] synonym: "nephron epithelium formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004209 ! results in formation of anatomical entity renal vesicle relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072077 ! renal vesicle morphogenesis relationship: RO:0002297 UBERON:0004209 ! results in formation of anatomical entity renal vesicle created_by: mah creation_date: 2010-01-25T02:57:03Z [Term] id: GO:0072036 name: mesenchymal to epithelial transition involved in renal vesicle formation def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0072033 ! renal vesicle formation relationship: part_of GO:0072033 ! renal vesicle formation created_by: mah creation_date: 2010-01-25T03:04:24Z [Term] id: GO:0072038 name: mesenchymal stem cell maintenance involved in nephron morphogenesis def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0035019 ! somatic stem cell population maintenance relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072028 ! nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:08:05Z [Term] id: GO:0072039 name: regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904672 ! regulation of somatic stem cell population maintenance is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1901145 ! regulates mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0072038 ! regulates mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: RO:0002211 GO:1901145 ! regulates mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:08:34Z [Term] id: GO:0072040 name: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis is_a: GO:1904673 ! negative regulation of somatic stem cell population maintenance is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1901145 ! negatively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: RO:0002212 GO:0072038 ! negatively regulates mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: RO:0002212 GO:1901145 ! negatively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:09:30Z [Term] id: GO:0072041 name: positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis is_a: GO:1904674 ! positive regulation of somatic stem cell population maintenance is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1901145 ! positively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: RO:0002213 GO:0072038 ! positively regulates mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: RO:0002213 GO:1901145 ! positively regulates mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:10:32Z [Term] id: GO:0072044 name: collecting duct development def: "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001232 ! results in development of collecting duct of renal tubule relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0001232 ! results in development of collecting duct of renal tubule created_by: mah creation_date: 2010-01-25T03:18:06Z [Term] id: GO:0072048 name: renal system pattern specification def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system." [GOC:mtg_kidney_jan10] subset: gocheck_do_not_annotate synonym: "renal system pattern formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0072001 ! renal system development created_by: mah creation_date: 2010-01-25T03:31:51Z [Term] id: GO:0072055 name: renal cortex development def: "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001225 ! results in development of cortex of kidney relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0001225 ! results in development of cortex of kidney created_by: mah creation_date: 2010-01-25T04:01:12Z [Term] id: GO:0072056 name: pyramid development def: "The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts." [GOC:mtg_kidney_jan10] synonym: "kidney pyramid development" EXACT [GOC:mah] synonym: "pyramids development" EXACT [GOC:mah] synonym: "renal medulla development" EXACT [GOC:mah] synonym: "renal pyramid development" EXACT [GOC:mah] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004200 ! results in development of kidney pyramid relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0004200 ! results in development of kidney pyramid created_by: mah creation_date: 2010-01-25T04:01:36Z [Term] id: GO:0072059 name: cortical collecting duct development def: "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004203 ! results in development of cortical collecting duct relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002296 UBERON:0004203 ! results in development of cortical collecting duct created_by: mah creation_date: 2010-01-25T04:07:07Z [Term] id: GO:0072071 name: kidney interstitial fibroblast differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000692 ! results in acquisition of features of kidney interstitial fibroblast relationship: RO:0002315 CL:1000692 ! results in acquisition of features of kidney interstitial fibroblast created_by: mah creation_date: 2010-01-25T04:34:31Z [Term] id: GO:0072073 name: kidney epithelium development def: "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004819 ! results in development of kidney epithelium relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0004819 ! results in development of kidney epithelium created_by: mah creation_date: 2010-01-25T04:37:42Z [Term] id: GO:0072074 name: kidney mesenchyme development def: "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003918 ! results in development of kidney mesenchyme relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0003918 ! results in development of kidney mesenchyme created_by: mah creation_date: 2010-01-25T04:39:04Z [Term] id: GO:0072075 name: metanephric mesenchyme development def: "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003220 ! results in development of metanephric mesenchyme relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0003220 ! results in development of metanephric mesenchyme created_by: mah creation_date: 2010-01-25T04:40:11Z [Term] id: GO:0072076 name: nephrogenic mesenchyme development def: "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004208 ! results in development of nephrogenic mesenchyme relationship: part_of GO:0072006 ! nephron development relationship: RO:0002296 UBERON:0004208 ! results in development of nephrogenic mesenchyme created_by: mah creation_date: 2010-01-25T04:40:44Z [Term] id: GO:0072077 name: renal vesicle morphogenesis def: "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004209 ! results in morphogenesis of renal vesicle relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072087 ! renal vesicle development relationship: part_of GO:0072088 ! nephron epithelium morphogenesis relationship: RO:0002298 UBERON:0004209 ! results in morphogenesis of renal vesicle created_by: mah creation_date: 2010-02-01T02:21:06Z [Term] id: GO:0072078 name: nephron tubule morphogenesis def: "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061333 ! renal tubule morphogenesis is_a: GO:0072088 ! nephron epithelium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001231 ! results in morphogenesis of nephron tubule relationship: part_of GO:0072080 ! nephron tubule development relationship: RO:0002298 UBERON:0001231 ! results in morphogenesis of nephron tubule created_by: mah creation_date: 2010-02-01T02:25:14Z [Term] id: GO:0072079 name: nephron tubule formation def: "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001231 ! results in formation of anatomical entity nephron tubule relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072078 ! nephron tubule morphogenesis relationship: RO:0002297 UBERON:0001231 ! results in formation of anatomical entity nephron tubule created_by: mah creation_date: 2010-02-01T02:29:26Z [Term] id: GO:0072080 name: nephron tubule development def: "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061326 ! renal tubule development is_a: GO:0072009 ! nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001231 ! results in development of nephron tubule relationship: RO:0002296 UBERON:0001231 ! results in development of nephron tubule created_by: mah creation_date: 2010-02-01T02:32:12Z [Term] id: GO:0072087 name: renal vesicle development def: "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004209 ! results in development of renal vesicle relationship: part_of GO:0072009 ! nephron epithelium development relationship: RO:0002296 UBERON:0004209 ! results in development of renal vesicle created_by: mah creation_date: 2010-02-08T01:18:31Z [Term] id: GO:0072088 name: nephron epithelium morphogenesis def: "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004211 ! results in morphogenesis of nephron epithelium relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072009 ! nephron epithelium development relationship: part_of GO:0072028 ! nephron morphogenesis relationship: RO:0002298 UBERON:0004211 ! results in morphogenesis of nephron epithelium created_by: mah creation_date: 2010-02-08T01:19:06Z [Term] id: GO:0072089 name: stem cell proliferation def: "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000034 ! acts on population of stem cell relationship: has_part GO:0017145 ! stem cell division relationship: RO:0012003 CL:0000034 ! acts on population of stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: mah creation_date: 2010-02-08T02:03:36Z [Term] id: GO:0072091 name: regulation of stem cell proliferation def: "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072089 ! regulates stem cell proliferation relationship: RO:0002211 GO:0072089 ! regulates stem cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: mah creation_date: 2010-02-08T02:09:03Z [Term] id: GO:0072093 name: metanephric renal vesicle formation def: "The developmental process pertaining to the initial formation of the metanephros." [GOC:mtg_kidney_jan10] synonym: "metanephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005147 ! results in formation of anatomical entity metanephric renal vesicle relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis relationship: RO:0002297 UBERON:0005147 ! results in formation of anatomical entity metanephric renal vesicle created_by: mah creation_date: 2010-02-10T01:17:11Z [Term] id: GO:0072098 name: anterior/posterior pattern specification involved in kidney development def: "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "anterior/posterior pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney anterior/posterior pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-02-10T02:06:24Z [Term] id: GO:0072099 name: anterior/posterior pattern specification involved in ureteric bud development def: "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "ureteric bud anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0061227 ! pattern specification involved in mesonephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0001657 ! ureteric bud development relationship: part_of GO:0001657 ! ureteric bud development created_by: mah creation_date: 2010-02-10T02:12:09Z [Term] id: GO:0072105 name: ureteric peristalsis def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0014849 ! ureter smooth muscle contraction is_a: GO:0030432 ! peristalsis intersection_of: GO:0030432 ! peristalsis intersection_of: BFO:0000066 UBERON:0000056 ! occurs in ureter relationship: BFO:0000066 UBERON:0000056 ! occurs in ureter property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mah creation_date: 2010-02-10T03:07:54Z [Term] id: GO:0072106 name: regulation of ureteric bud formation def: "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060676 ! regulates ureteric bud formation relationship: RO:0002211 GO:0060676 ! regulates ureteric bud formation created_by: mah creation_date: 2010-02-12T02:34:40Z [Term] id: GO:0072107 name: positive regulation of ureteric bud formation def: "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0072106 ! regulation of ureteric bud formation is_a: GO:0110110 ! positive regulation of animal organ morphogenesis is_a: GO:1905278 ! positive regulation of epithelial tube formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060676 ! positively regulates ureteric bud formation relationship: RO:0002213 GO:0060676 ! positively regulates ureteric bud formation created_by: mah creation_date: 2010-02-12T02:37:28Z [Term] id: GO:0072108 name: positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis def: "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003337 ! positively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: RO:0002213 GO:0003337 ! positively regulates mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: mah creation_date: 2010-02-12T02:45:57Z [Term] id: GO:0072111 name: cell proliferation involved in kidney development def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001822 ! kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-02-22T10:48:45Z [Term] id: GO:0072114 name: pronephros morphogenesis def: "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney morphogenesis" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002120 ! results in morphogenesis of pronephros relationship: part_of GO:0048793 ! pronephros development relationship: RO:0002298 UBERON:0002120 ! results in morphogenesis of pronephros created_by: mah creation_date: 2010-02-22T11:12:15Z [Term] id: GO:0072116 name: pronephros formation def: "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048645 ! animal organ formation is_a: GO:0072003 ! kidney rudiment formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002120 ! results in formation of anatomical entity pronephros relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: RO:0002297 UBERON:0002120 ! results in formation of anatomical entity pronephros created_by: mah creation_date: 2010-02-22T11:16:26Z [Term] id: GO:0072120 name: pronephros maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney maturation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 UBERON:0002120 ! results in maturation of pronephros relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0048793 ! pronephros development relationship: RO:0002299 UBERON:0002120 ! results in maturation of pronephros created_by: mah creation_date: 2010-02-22T11:25:48Z [Term] id: GO:0072127 name: renal capsule development def: "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002015 ! results in development of kidney capsule relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development relationship: RO:0002296 UBERON:0002015 ! results in development of kidney capsule created_by: mah creation_date: 2010-02-22T02:02:55Z [Term] id: GO:0072128 name: renal capsule morphogenesis def: "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002015 ! results in morphogenesis of kidney capsule relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072127 ! renal capsule development relationship: RO:0002298 UBERON:0002015 ! results in morphogenesis of kidney capsule created_by: mah creation_date: 2010-02-22T02:06:19Z [Term] id: GO:0072129 name: renal capsule formation def: "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0002015 ! results in formation of anatomical entity kidney capsule relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072128 ! renal capsule morphogenesis relationship: RO:0002297 UBERON:0002015 ! results in formation of anatomical entity kidney capsule created_by: mah creation_date: 2010-02-22T02:08:14Z [Term] id: GO:0072131 name: kidney mesenchyme morphogenesis def: "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003918 ! results in morphogenesis of kidney mesenchyme relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072074 ! kidney mesenchyme development relationship: RO:0002298 UBERON:0003918 ! results in morphogenesis of kidney mesenchyme created_by: mah creation_date: 2010-02-22T02:16:43Z [Term] id: GO:0072132 name: mesenchyme morphogenesis def: "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003104 ! results in morphogenesis of mesenchyme relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: part_of GO:0060485 ! mesenchyme development relationship: RO:0002298 UBERON:0003104 ! results in morphogenesis of mesenchyme created_by: mah creation_date: 2010-02-22T02:17:15Z [Term] id: GO:0072133 name: metanephric mesenchyme morphogenesis def: "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003220 ! results in morphogenesis of metanephric mesenchyme relationship: part_of GO:0072075 ! metanephric mesenchyme development relationship: RO:0002298 UBERON:0003220 ! results in morphogenesis of metanephric mesenchyme created_by: mah creation_date: 2010-02-22T02:20:14Z [Term] id: GO:0072134 name: nephrogenic mesenchyme morphogenesis def: "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0004208 ! results in morphogenesis of nephrogenic mesenchyme relationship: part_of GO:0072076 ! nephrogenic mesenchyme development relationship: RO:0002298 UBERON:0004208 ! results in morphogenesis of nephrogenic mesenchyme created_by: mah creation_date: 2010-02-22T02:21:16Z [Term] id: GO:0072138 name: mesenchymal cell proliferation involved in ureteric bud development def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development." [GOC:mtg_kidney_jan10] synonym: "ureteric bud mesenchymal cell proliferation" BROAD [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation is_a: GO:0061209 ! cell proliferation involved in mesonephros development intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0001657 ! ureteric bud development relationship: part_of GO:0001657 ! ureteric bud development created_by: mah creation_date: 2010-02-22T02:40:38Z [Term] id: GO:0072141 name: renal interstitial fibroblast development def: "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048468 ! cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:1000692 ! results in development of kidney interstitial fibroblast relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072071 ! kidney interstitial fibroblast differentiation relationship: RO:0002296 CL:1000692 ! results in development of kidney interstitial fibroblast created_by: mah creation_date: 2010-02-24T01:39:05Z [Term] id: GO:0072155 name: epithelial cell migration involved in nephron tubule morphogenesis def: "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0010631 ! epithelial cell migration is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0010631 ! epithelial cell migration intersection_of: part_of GO:0072078 ! nephron tubule morphogenesis relationship: part_of GO:0072078 ! nephron tubule morphogenesis created_by: mah creation_date: 2010-02-24T02:21:25Z [Term] id: GO:0072160 name: nephron tubule epithelial cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000494 ! results in acquisition of features of nephron tubule epithelial cell relationship: part_of GO:0072080 ! nephron tubule development relationship: RO:0002315 CL:1000494 ! results in acquisition of features of nephron tubule epithelial cell created_by: mah creation_date: 2010-02-24T02:40:11Z [Term] id: GO:0072161 name: mesenchymal cell differentiation involved in kidney development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development is_a: GO:2001012 ! mesenchymal cell differentiation involved in renal system development intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0072074 ! kidney mesenchyme development created_by: mah creation_date: 2010-02-26T01:31:49Z [Term] id: GO:0072163 name: mesonephric epithelium development def: "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005103 ! results in development of mesonephric epithelium relationship: part_of GO:0001823 ! mesonephros development relationship: RO:0002296 UBERON:0005103 ! results in development of mesonephric epithelium created_by: mah creation_date: 2010-02-26T01:40:43Z [Term] id: GO:0072164 name: mesonephric tubule development def: "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000083 ! results in development of mesonephric tubule relationship: RO:0002296 UBERON:0000083 ! results in development of mesonephric tubule created_by: mah creation_date: 2010-02-26T01:45:58Z [Term] id: GO:0072170 name: metanephric tubule development def: "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005106 ! results in development of metanephric tubule relationship: RO:0002296 UBERON:0005106 ! results in development of metanephric tubule created_by: mah creation_date: 2010-02-26T01:58:18Z [Term] id: GO:0072171 name: mesonephric tubule morphogenesis def: "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000083 ! results in morphogenesis of mesonephric tubule relationship: part_of GO:0072164 ! mesonephric tubule development relationship: RO:0002298 UBERON:0000083 ! results in morphogenesis of mesonephric tubule created_by: mah creation_date: 2010-02-26T02:02:13Z [Term] id: GO:0072172 name: mesonephric tubule formation def: "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000083 ! results in formation of anatomical entity mesonephric tubule relationship: part_of GO:0072171 ! mesonephric tubule morphogenesis relationship: RO:0002297 UBERON:0000083 ! results in formation of anatomical entity mesonephric tubule created_by: mah creation_date: 2010-02-26T02:02:37Z [Term] id: GO:0072173 name: metanephric tubule morphogenesis def: "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005106 ! results in morphogenesis of metanephric tubule relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072170 ! metanephric tubule development relationship: RO:0002298 UBERON:0005106 ! results in morphogenesis of metanephric tubule created_by: mah creation_date: 2010-02-26T02:06:42Z [Term] id: GO:0072174 name: metanephric tubule formation def: "The developmental process pertaining to the initial formation of a metanephric tubule." [GOC:mtg_kidney_jan10] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005106 ! results in formation of anatomical entity metanephric tubule relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072173 ! metanephric tubule morphogenesis relationship: RO:0002297 UBERON:0005106 ! results in formation of anatomical entity metanephric tubule created_by: mah creation_date: 2010-02-26T02:07:41Z [Term] id: GO:0072175 name: epithelial tube formation def: "The developmental process pertaining to the initial formation of an epithelial tube." [GOC:mtg_kidney_jan10] is_a: GO:0035148 ! tube formation intersection_of: GO:0035148 ! tube formation intersection_of: RO:0002297 UBERON:0003914 ! results in formation of anatomical entity epithelial tube relationship: part_of GO:0060562 ! epithelial tube morphogenesis relationship: RO:0002297 UBERON:0003914 ! results in formation of anatomical entity epithelial tube property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI created_by: mah creation_date: 2010-02-26T02:15:40Z [Term] id: GO:0072176 name: nephric duct development def: "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009201 ! results in development of nephric duct relationship: RO:0002296 UBERON:0009201 ! results in development of nephric duct created_by: mah creation_date: 2010-02-26T02:27:31Z [Term] id: GO:0072177 name: mesonephric duct development def: "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct development" EXACT [GOC:dph] is_a: GO:0072164 ! mesonephric tubule development is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003074 ! results in development of mesonephric duct relationship: RO:0002296 UBERON:0003074 ! results in development of mesonephric duct created_by: mah creation_date: 2010-02-26T02:32:22Z [Term] id: GO:0072178 name: nephric duct morphogenesis def: "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0009201 ! results in morphogenesis of nephric duct relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072176 ! nephric duct development relationship: RO:0002298 UBERON:0009201 ! results in morphogenesis of nephric duct created_by: mah creation_date: 2010-02-26T02:35:29Z [Term] id: GO:0072179 name: nephric duct formation def: "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] xref: Reactome:R-HSA-9830364 "Formation of the nephric duct" is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0009201 ! results in formation of anatomical entity nephric duct relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072178 ! nephric duct morphogenesis relationship: RO:0002297 UBERON:0009201 ! results in formation of anatomical entity nephric duct created_by: mah creation_date: 2010-02-26T02:35:55Z [Term] id: GO:0072180 name: mesonephric duct morphogenesis def: "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct morphogenesis" RELATED [GOC:dph] is_a: GO:0072171 ! mesonephric tubule morphogenesis is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003074 ! results in morphogenesis of mesonephric duct relationship: part_of GO:0072177 ! mesonephric duct development relationship: RO:0002298 UBERON:0003074 ! results in morphogenesis of mesonephric duct created_by: mah creation_date: 2010-02-26T02:37:13Z [Term] id: GO:0072181 name: mesonephric duct formation def: "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct formation" EXACT [GOC:dph] is_a: GO:0072172 ! mesonephric tubule formation is_a: GO:0072179 ! nephric duct formation is_a: GO:0072180 ! mesonephric duct morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0003074 ! results in formation of anatomical entity mesonephric duct relationship: RO:0002297 UBERON:0003074 ! results in formation of anatomical entity mesonephric duct created_by: mah creation_date: 2010-02-26T02:38:03Z [Term] id: GO:0072182 name: regulation of nephron tubule epithelial cell differentiation def: "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072160 ! regulates nephron tubule epithelial cell differentiation relationship: RO:0002211 GO:0072160 ! regulates nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-02-26T02:45:09Z [Term] id: GO:0072183 name: negative regulation of nephron tubule epithelial cell differentiation def: "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:0090185 ! negative regulation of kidney development is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072160 ! negatively regulates nephron tubule epithelial cell differentiation relationship: RO:0002212 GO:0072160 ! negatively regulates nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-02-26T02:47:25Z [Term] id: GO:0072189 name: ureter development def: "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000056 ! results in development of ureter relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072001 ! renal system development relationship: RO:0002296 UBERON:0000056 ! results in development of ureter created_by: mah creation_date: 2010-03-01T01:44:14Z [Term] id: GO:0072191 name: ureter smooth muscle development def: "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0009919 ! results in development of ureter smooth muscle relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072189 ! ureter development relationship: RO:0002296 UBERON:0009919 ! results in development of ureter smooth muscle created_by: mah creation_date: 2010-03-01T01:48:53Z [Term] id: GO:0072193 name: ureter smooth muscle cell differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter." [GOC:mtg_kidney_jan10] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000979 ! results in acquisition of features of ureter smooth muscle cell relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072191 ! ureter smooth muscle development relationship: RO:0002315 CL:1000979 ! results in acquisition of features of ureter smooth muscle cell created_by: mah creation_date: 2010-03-01T01:55:01Z [Term] id: GO:0072194 name: kidney smooth muscle tissue development def: "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-03-01T02:05:30Z [Term] id: GO:0072197 name: ureter morphogenesis def: "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000056 ! results in morphogenesis of ureter relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072189 ! ureter development relationship: RO:0002298 UBERON:0000056 ! results in morphogenesis of ureter created_by: mah creation_date: 2010-03-01T02:24:55Z [Term] id: GO:0072198 name: mesenchymal cell proliferation involved in ureter development def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development." [GOC:mtg_kidney_jan10] synonym: "ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0072189 ! ureter development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072189 ! ureter development created_by: mah creation_date: 2010-03-01T03:24:41Z [Term] id: GO:0072199 name: regulation of mesenchymal cell proliferation involved in ureter development def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] synonym: "regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072198 ! regulates mesenchymal cell proliferation involved in ureter development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0072198 ! regulates mesenchymal cell proliferation involved in ureter development created_by: mah creation_date: 2010-03-01T03:38:13Z [Term] id: GO:0072200 name: negative regulation of mesenchymal cell proliferation involved in ureter development def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] synonym: "negative regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "negative regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072198 ! negatively regulates mesenchymal cell proliferation involved in ureter development relationship: RO:0002212 GO:0072198 ! negatively regulates mesenchymal cell proliferation involved in ureter development created_by: mah creation_date: 2010-03-01T03:42:31Z [Term] id: GO:0072201 name: negative regulation of mesenchymal cell proliferation def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010463 ! negatively regulates mesenchymal cell proliferation relationship: RO:0002212 GO:0010463 ! negatively regulates mesenchymal cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: mah creation_date: 2010-03-01T03:43:29Z [Term] id: GO:0072202 name: cell differentiation involved in metanephros development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state." [GOC:mah, GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:40:14Z [Term] id: GO:0072203 name: cell proliferation involved in metanephros development def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:42:27Z [Term] id: GO:0072204 name: cell-cell signaling involved in metanephros development def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in metanephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:54:36Z [Term] id: GO:0072205 name: metanephric collecting duct development def: "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004737 ! results in development of metanephric collecting duct relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0004737 ! results in development of metanephric collecting duct created_by: mah creation_date: 2010-03-18T11:15:37Z [Term] id: GO:0072207 name: metanephric epithelium development def: "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005108 ! results in development of metanephric epithelium relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0005108 ! results in development of metanephric epithelium created_by: mah creation_date: 2010-03-18T11:50:37Z [Term] id: GO:0072208 name: metanephric smooth muscle tissue development def: "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005109 ! results in development of metanephric smooth muscle tissue relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0005109 ! results in development of metanephric smooth muscle tissue created_by: mah creation_date: 2010-03-18T11:51:59Z [Term] id: GO:0072210 name: metanephric nephron development def: "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] xref: Reactome:R-HSA-9831926 "Nephron development" is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005110 ! results in development of metanephric nephron relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0005110 ! results in development of metanephric nephron created_by: mah creation_date: 2010-03-18T12:52:57Z [Term] id: GO:0072211 name: metanephric pyramids development def: "The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts." [GOC:mtg_kidney_jan10] synonym: "metanephric kidney pyramid development" EXACT [GOC:mah] synonym: "metanephric pyramid development" EXACT [GOC:mah] synonym: "metanephric renal medulla development" EXACT [GOC:mah] synonym: "metanephric renal pyramid development" EXACT [GOC:mah] is_a: GO:0072056 ! pyramid development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005111 ! results in development of metanephric pyramid relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0005111 ! results in development of metanephric pyramid created_by: mah creation_date: 2010-03-18T01:04:51Z [Term] id: GO:0072213 name: metanephric capsule development def: "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005137 ! results in development of metanephric capsule relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0005137 ! results in development of metanephric capsule created_by: mah creation_date: 2010-03-18T01:25:19Z [Term] id: GO:0072214 name: metanephric cortex development def: "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development is_a: GO:0072055 ! renal cortex development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005113 ! results in development of metanephric cortex mesenchyme relationship: part_of GO:0001656 ! metanephros development relationship: RO:0002296 UBERON:0005113 ! results in development of metanephric cortex mesenchyme created_by: mah creation_date: 2010-03-18T01:29:49Z [Term] id: GO:0072215 name: regulation of metanephros development def: "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001656 ! regulates metanephros development relationship: RO:0002211 GO:0001656 ! regulates metanephros development [Term] id: GO:0072216 name: positive regulation of metanephros development def: "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001656 ! positively regulates metanephros development relationship: RO:0002213 GO:0001656 ! positively regulates metanephros development created_by: mah creation_date: 2010-03-18T01:40:12Z [Term] id: GO:0072217 name: negative regulation of metanephros development def: "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001656 ! negatively regulates metanephros development relationship: RO:0002212 GO:0001656 ! negatively regulates metanephros development created_by: mah creation_date: 2010-03-18T01:45:48Z [Term] id: GO:0072219 name: metanephric cortical collecting duct development def: "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0072059 ! cortical collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005115 ! results in development of metanephric cortical collecting duct relationship: RO:0002296 UBERON:0005115 ! results in development of metanephric cortical collecting duct created_by: mah creation_date: 2010-03-18T03:34:52Z [Term] id: GO:0072234 name: metanephric nephron tubule development def: "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072080 ! nephron tubule development is_a: GO:0072170 ! metanephric tubule development is_a: GO:0072243 ! metanephric nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005146 ! results in development of metanephric nephron tubule relationship: RO:0002296 UBERON:0005146 ! results in development of metanephric nephron tubule created_by: mah creation_date: 2010-03-18T03:41:23Z [Term] id: GO:0072243 name: metanephric nephron epithelium development def: "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005134 ! results in development of metanephric nephron epithelium relationship: RO:0002296 UBERON:0005134 ! results in development of metanephric nephron epithelium created_by: mah creation_date: 2010-03-19T03:29:49Z [Term] id: GO:0072257 name: metanephric nephron tubule epithelial cell differentiation def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0072160 ! nephron tubule epithelial cell differentiation is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:1000123 ! results in acquisition of features of metanephric nephron tubule epithelial cell relationship: part_of GO:0072234 ! metanephric nephron tubule development relationship: RO:0002315 CL:1000123 ! results in acquisition of features of metanephric nephron tubule epithelial cell created_by: mah creation_date: 2010-03-19T04:11:02Z [Term] id: GO:0072265 name: metanephric capsule morphogenesis def: "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005137 ! results in morphogenesis of metanephric capsule relationship: part_of GO:0072213 ! metanephric capsule development relationship: RO:0002298 UBERON:0005137 ! results in morphogenesis of metanephric capsule created_by: mah creation_date: 2010-03-30T02:54:49Z [Term] id: GO:0072266 name: metanephric capsule formation def: "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005137 ! results in formation of anatomical entity metanephric capsule relationship: part_of GO:0072265 ! metanephric capsule morphogenesis relationship: RO:0002297 UBERON:0005137 ! results in formation of anatomical entity metanephric capsule created_by: mah creation_date: 2010-03-30T02:56:35Z [Term] id: GO:0072268 name: pattern specification involved in metanephros development def: "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "metanephros pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "metanephros pattern specification" EXACT [GOC:mtg_kidney_jan10] synonym: "pattern formation involved in metanephros development" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-30T03:06:30Z [Term] id: GO:0072273 name: metanephric nephron morphogenesis def: "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005110 ! results in morphogenesis of metanephric nephron relationship: part_of GO:0003338 ! metanephros morphogenesis relationship: part_of GO:0072210 ! metanephric nephron development relationship: RO:0002298 UBERON:0005110 ! results in morphogenesis of metanephric nephron created_by: mah creation_date: 2010-03-30T03:33:19Z [Term] id: GO:0072282 name: metanephric nephron tubule morphogenesis def: "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis is_a: GO:0072173 ! metanephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005146 ! results in morphogenesis of metanephric nephron tubule relationship: part_of GO:0072234 ! metanephric nephron tubule development relationship: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: RO:0002298 UBERON:0005146 ! results in morphogenesis of metanephric nephron tubule created_by: mah creation_date: 2010-04-01T03:25:11Z [Term] id: GO:0072283 name: metanephric renal vesicle morphogenesis def: "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005147 ! results in morphogenesis of metanephric renal vesicle relationship: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: RO:0002298 UBERON:0005147 ! results in morphogenesis of metanephric renal vesicle created_by: mah creation_date: 2010-04-01T03:28:00Z [Term] id: GO:0072285 name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0072093 ! metanephric renal vesicle formation relationship: part_of GO:0072093 ! metanephric renal vesicle formation created_by: mah creation_date: 2010-04-01T03:43:31Z [Term] id: GO:0072289 name: metanephric nephron tubule formation def: "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation is_a: GO:0072174 ! metanephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0005146 ! results in formation of anatomical entity metanephric nephron tubule relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis relationship: RO:0002297 UBERON:0005146 ! results in formation of anatomical entity metanephric nephron tubule created_by: mah creation_date: 2010-04-09T03:47:44Z [Term] id: GO:0072290 name: epithelial cell migration involved in metanephric nephron tubule morphogenesis def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0035788 ! cell migration involved in metanephros development is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis intersection_of: GO:0010631 ! epithelial cell migration intersection_of: part_of GO:0072282 ! metanephric nephron tubule morphogenesis relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis created_by: mah creation_date: 2010-04-09T03:52:29Z [Term] id: GO:0072304 name: regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1901147 ! regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: RO:0002211 GO:0072309 ! regulates mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: RO:0002211 GO:1901147 ! regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072305 name: negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900212 ! negative regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1901147 ! negatively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: RO:0002212 GO:0072309 ! negatively regulates mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: RO:0002212 GO:1901147 ! negatively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072306 name: positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900213 ! positive regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1901147 ! positively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: RO:0002213 GO:0072309 ! positively regulates mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: RO:0002213 GO:1901147 ! positively regulates mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072307 name: regulation of metanephric nephron tubule epithelial cell differentiation def: "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072257 ! regulates metanephric nephron tubule epithelial cell differentiation relationship: RO:0002211 GO:0072257 ! regulates metanephric nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072308 name: negative regulation of metanephric nephron tubule epithelial cell differentiation def: "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072183 ! negative regulation of nephron tubule epithelial cell differentiation is_a: GO:0072307 ! regulation of metanephric nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072257 ! negatively regulates metanephric nephron tubule epithelial cell differentiation relationship: RO:0002212 GO:0072257 ! negatively regulates metanephric nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072309 name: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: part_of GO:0072273 ! metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072329 name: monocarboxylic acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion relationship: RO:0004009 CHEBI:35757 ! has primary input monocarboxylic acid anion created_by: mah creation_date: 2010-11-02T04:41:55Z [Term] id: GO:0072330 name: monocarboxylic acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] synonym: "monocarboxylic acid anabolism" EXACT [GOC:mah] synonym: "monocarboxylic acid biosynthesis" EXACT [GOC:mah] synonym: "monocarboxylic acid formation" EXACT [GOC:mah] synonym: "monocarboxylic acid synthesis" EXACT [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:35757 ! has primary output monocarboxylic acid anion relationship: RO:0004008 CHEBI:35757 ! has primary output monocarboxylic acid anion created_by: mah creation_date: 2010-11-02T04:51:32Z [Term] id: GO:0072348 name: sulfur compound transport def: "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "sulfur-containing compound transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity relationship: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity created_by: mah creation_date: 2010-11-11T11:43:56Z [Term] id: GO:0072359 name: circulatory system development alt_id: GO:0072358 def: "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." [GOC:mah, UBERON:0001009] subset: goslim_drosophila synonym: "cardiovascular system development" NARROW [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001009 ! results in development of circulatory system relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002296 UBERON:0001009 ! results in development of circulatory system created_by: mah creation_date: 2010-11-16T11:27:39Z [Term] id: GO:0072360 name: vascular cord development def: "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." [GOC:mah, PMID:7084422, ZFA:0005077] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006965 ! results in development of vascular cord relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0072359 ! circulatory system development relationship: RO:0002296 UBERON:0006965 ! results in development of vascular cord created_by: mah creation_date: 2010-11-16T11:46:55Z [Term] id: GO:0072384 name: organelle transport along microtubule def: "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:mah] synonym: "microtubule-based organelle localization" EXACT [GOC:rl] is_a: GO:0010970 ! transport along microtubule is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0043226 ! has primary input organelle created_by: mah creation_date: 2010-12-01T04:59:11Z [Term] id: GO:0072488 name: ammonium transmembrane transport alt_id: GO:0015696 def: "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "ammonia transport" BROAD [] synonym: "ammonium membrane transport" EXACT [] synonym: "ammonium transport" BROAD [] is_a: GO:0055085 ! transmembrane transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22228" xsd:anyURI created_by: mah creation_date: 2010-12-10T10:29:57Z [Term] id: GO:0072520 name: seminiferous tubule development def: "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa." [GOC:BHF, GOC:mah, UBERON:0001343] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001343 ! results in development of seminiferous tubule of testis relationship: part_of GO:0008584 ! male gonad development relationship: RO:0002296 UBERON:0001343 ! results in development of seminiferous tubule of testis created_by: mah creation_date: 2011-01-04T12:50:36Z [Term] id: GO:0072537 name: fibroblast activation def: "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [CL:0000057, GOC:BHF, GOC:mah] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: RO:0004009 CL:0000057 ! has primary input fibroblast relationship: RO:0004009 CL:0000057 ! has primary input fibroblast created_by: mah creation_date: 2011-01-14T04:35:08Z [Term] id: GO:0072560 name: type B pancreatic cell maturation def: "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF] comment: These processes continue to 60 DPA in Gossypium spp. synonym: "pancreatic B cell maturation" EXACT [CL:0000169, GOC:mah] synonym: "pancreatic beta cell maturation" EXACT [CL:0000169, GOC:mah] is_a: GO:0002070 ! epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 CL:0000169 ! results in maturation of type B pancreatic cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003323 ! type B pancreatic cell development relationship: RO:0002299 CL:0000169 ! results in maturation of type B pancreatic cell created_by: mah creation_date: 2011-01-27T01:57:14Z [Term] id: GO:0072575 name: epithelial cell proliferation involved in liver morphogenesis def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver." [GOC:BHF, GOC:mah] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0072576 ! liver morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0072576 ! liver morphogenesis created_by: mah creation_date: 2011-02-02T03:37:50Z [Term] id: GO:0072576 name: liver morphogenesis def: "The process in which the anatomical structures of the liver are generated and organized." [GOC:mah] is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002107 ! results in morphogenesis of liver relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0001889 ! liver development relationship: RO:0002298 UBERON:0002107 ! results in morphogenesis of liver created_by: mah creation_date: 2011-02-02T03:41:30Z [Term] id: GO:0072577 name: endothelial cell apoptotic process def: "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "apoptosis of endothelial cells" EXACT [GOC:mah] synonym: "endothelial cell apoptosis" NARROW [] synonym: "endothelial cell programmed cell death by apoptosis" EXACT [GOC:mah] synonym: "killing of endothelial cells" EXACT [GOC:mah] synonym: "programmed cell death of endothelial cells by apoptosis" EXACT [GOC:mah] synonym: "programmed cell death, endothelial cells" EXACT [GOC:mah] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000115 ! occurs in endothelial cell relationship: BFO:0000066 CL:0000115 ! occurs in endothelial cell property_value: RO:0002161 NCBITaxon:4896 created_by: mah creation_date: 2011-02-02T03:56:24Z [Term] id: GO:0072592 name: oxygen metabolic process def: "The chemical reactions and pathways involving diatomic oxygen (O2)." [GOC:mah] synonym: "diatomic oxygen metabolic process" EXACT [CHEBI:33263] synonym: "oxygen metabolism" EXACT [GOC:mah] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:15379 ! has primary input or output dioxygen relationship: RO:0004007 CHEBI:15379 ! has primary input or output dioxygen created_by: mah creation_date: 2011-02-11T10:46:51Z [Term] id: GO:0072594 name: establishment of protein localization to organelle def: "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah] synonym: "establishment of protein localisation to organelle" EXACT [GOC:mah] is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0043226 ! has target end location organelle relationship: RO:0002339 GO:0043226 ! has target end location organelle created_by: mah creation_date: 2011-02-14T01:56:51Z [Term] id: GO:0072595 name: maintenance of protein localization in organelle def: "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah] synonym: "maintenance of protein localisation to organelle" EXACT [GOC:mah] synonym: "maintenance of protein localization to organelle" EXACT [] is_a: GO:0032507 ! maintenance of protein location in cell intersection_of: GO:0045185 ! maintenance of protein location intersection_of: BFO:0000066 GO:0043226 ! occurs in organelle relationship: BFO:0000066 GO:0043226 ! occurs in organelle relationship: part_of GO:0033365 ! protein localization to organelle created_by: mah creation_date: 2011-02-14T02:09:13Z [Term] id: GO:0072657 name: protein localization to membrane def: "A process in which a protein is transported to, or maintained in, a specific location in a membrane." [GOC:mah] subset: goslim_prokaryote synonym: "protein localisation in membrane" EXACT [GOC:mah] synonym: "protein localization in membrane" EXACT [] is_a: GO:0008104 ! intracellular protein localization is_a: GO:0051668 ! localization within membrane intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0016020 ! has target end location membrane created_by: mah creation_date: 2011-02-14T02:35:18Z [Term] id: GO:0072659 name: protein localization to plasma membrane alt_id: GO:0072661 alt_id: GO:0090002 def: "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." [GOC:mah] subset: goslim_generic subset: goslim_pombe synonym: "protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "protein localization in plasma membrane" RELATED [] synonym: "protein targeting to plasma membrane" RELATED [] synonym: "protein-plasma membrane targeting" RELATED [GOC:mah] is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane relationship: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure relationship: RO:0002339 GO:0005886 ! has target end location plasma membrane created_by: tb creation_date: 2009-07-10T10:29:23Z [Term] id: GO:0072665 name: protein localization to vacuole def: "A process in which a protein is transported to, or maintained at, a location in a vacuole." [GOC:ecd] synonym: "protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005773 ! has target end location vacuole relationship: RO:0002339 GO:0005773 ! has target end location vacuole created_by: mah creation_date: 2011-02-14T02:55:35Z [Term] id: GO:0072666 name: establishment of protein localization to vacuole def: "The directed movement of a protein to a specific location in a vacuole." [GOC:mah] synonym: "establishment of protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0005773 ! has target end location vacuole relationship: RO:0002339 GO:0005773 ! has target end location vacuole created_by: mah creation_date: 2011-02-14T02:56:29Z [Term] id: GO:0072667 name: maintenance of protein location in vacuole def: "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere." [GOC:mah] is_a: GO:0072595 ! maintenance of protein localization in organelle intersection_of: GO:0045185 ! maintenance of protein location intersection_of: BFO:0000066 GO:0005773 ! occurs in vacuole relationship: BFO:0000066 GO:0005773 ! occurs in vacuole relationship: part_of GO:0072665 ! protein localization to vacuole created_by: mah creation_date: 2011-02-14T02:56:57Z [Term] id: GO:0072676 name: lymphocyte migration def: "The movement of a lymphocyte within or between different tissues and organs of the body." [CL:0000542, GOC:BHF, GOC:mah] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000542 ! results in movement of lymphocyte relationship: RO:0002565 CL:0000542 ! results in movement of lymphocyte created_by: mah creation_date: 2011-02-22T03:38:12Z [Term] id: GO:0072678 name: T cell migration def: "The movement of a T cell within or between different tissues and organs of the body." [CL:0000084, GOC:BHF, GOC:mah] synonym: "T lymphocyte migration" EXACT [CL:0000084] synonym: "T-cell migration" EXACT [CL:0000084] synonym: "T-lymphocyte migration" EXACT [CL:0000084] is_a: GO:0072676 ! lymphocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000084 ! results in movement of T cell relationship: RO:0002565 CL:0000084 ! results in movement of T cell created_by: mah creation_date: 2011-02-22T03:40:40Z [Term] id: GO:0072697 name: protein localization to cell cortex def: "A process in which a protein is transported to, or maintained in, the cell cortex." [GOC:mah] synonym: "protein localisation to cell cortex" EXACT [GOC:mah] is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005938 ! has target end location cell cortex relationship: RO:0002339 GO:0005938 ! has target end location cell cortex created_by: mah creation_date: 2012-04-11T01:16:33Z [Term] id: GO:0072698 name: protein localization to microtubule cytoskeleton def: "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." [GOC:mah] synonym: "protein localisation to microtubule cytoskeleton" EXACT [GOC:mah] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0015630 ! has target end location microtubule cytoskeleton relationship: RO:0002339 GO:0015630 ! has target end location microtubule cytoskeleton created_by: mah creation_date: 2012-04-11T01:19:35Z [Term] id: GO:0080090 name: regulation of primary metabolic process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044238 ! regulates primary metabolic process relationship: RO:0002211 GO:0044238 ! regulates primary metabolic process created_by: dhl creation_date: 2009-04-22T04:30:52Z [Term] id: GO:0080134 name: regulation of response to stress def: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006950 ! regulates response to stress relationship: RO:0002211 GO:0006950 ! regulates response to stress created_by: dhl creation_date: 2009-05-06T04:51:28Z [Term] id: GO:0080144 name: intracellular amino acid homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell." [PMID:19955263] synonym: "amino acid homeostasis" BROAD [] synonym: "cellular amino acid homeostasis" EXACT [] is_a: GO:0055082 ! intracellular chemical homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis intersection_of: RO:0002332 CHEBI:35238 ! regulates levels of amino-acid zwitterion relationship: RO:0002332 CHEBI:35238 ! regulates levels of amino-acid zwitterion created_by: dhl creation_date: 2010-01-27T04:47:27Z [Term] id: GO:0080154 name: regulation of fertilization def: "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:DHL, PMID:20478994] is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009566 ! regulates fertilization relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0009566 ! regulates fertilization created_by: dhl creation_date: 2010-09-01T03:44:27Z [Term] id: GO:0085029 name: extracellular matrix assembly def: "The aggregation, arrangement and bonding together of the extracellular matrix." [GOC:jl] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0031012 ! results in assembly of extracellular matrix relationship: RO:0002588 GO:0031012 ! results in assembly of extracellular matrix created_by: jl creation_date: 2010-07-14T12:52:49Z [Term] id: GO:0086001 name: cardiac muscle cell action potential def: "An action potential that occurs in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell relationship: BFO:0000066 CL:0000746 ! occurs in cardiac muscle cell property_value: RO:0002161 NCBITaxon:4895 created_by: tb creation_date: 2011-11-10T07:45:11Z [Term] id: GO:0086015 name: SA node cell action potential def: "An action potential that occurs in a sinoatrial node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell action potential" EXACT [] synonym: "SAN cardiac muscle cell action potential" EXACT [] synonym: "sinoatrial node cardiac muscle cell action potential" EXACT [] synonym: "sinus node cardiac muscle cell action potential" NARROW [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:1000409 ! occurs in myocyte of sinoatrial node relationship: BFO:0000066 CL:1000409 ! occurs in myocyte of sinoatrial node relationship: part_of GO:0086018 ! SA node cell to atrial cardiac muscle cell signaling property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0086016 name: AV node cell action potential def: "An action potential that occurs in an atrioventricular node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:1000410 ! occurs in myocyte of atrioventricular node relationship: BFO:0000066 CL:1000410 ! occurs in myocyte of atrioventricular node relationship: part_of GO:0086027 ! AV node cell to bundle of His cell signaling property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086017 name: Purkinje myocyte action potential def: "An action potential that occurs in a Purkinje myocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: BFO:0000066 CL:0002068 ! occurs in Purkinje myocyte relationship: BFO:0000066 CL:0002068 ! occurs in Purkinje myocyte relationship: part_of GO:0086029 ! Purkinje myocyte to ventricular cardiac muscle cell signaling property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086018 name: SA node cell to atrial cardiac muscle cell signaling def: "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell signalling" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "sinus node cardiomyocyte to atrial cardiomyocyte signalling" NARROW [] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086070 ! SA node cell to atrial cardiac muscle cell communication property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-10T09:15:01Z [Term] id: GO:0086019 name: cell-cell signaling involved in cardiac conduction def: "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "cell-cell signalling involved in cardiac conduction" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling is_a: GO:0086065 ! cell communication involved in cardiac conduction intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0061337 ! cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2011-11-16T03:43:52Z [Term] id: GO:0086027 name: AV node cell to bundle of His cell signaling def: "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node to bundle of His cell signaling" EXACT [] synonym: "AV node cell to bundle of His cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086067 ! AV node cell to bundle of His cell communication property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086029 name: Purkinje myocyte to ventricular cardiac muscle cell signaling def: "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "Purkinje myocyte to ventricular cardiac muscle cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0002068 ! has start location Purkinje myocyte intersection_of: RO:0002232 CL:2000046 ! has end location ventricular cardiac muscle cell relationship: RO:0002231 CL:0002068 ! has start location Purkinje myocyte relationship: RO:0002232 CL:2000046 ! has end location ventricular cardiac muscle cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086065 name: cell communication involved in cardiac conduction def: "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0007154 ! cell communication intersection_of: GO:0007154 ! cell communication intersection_of: part_of GO:0061337 ! cardiac conduction relationship: part_of GO:0061337 ! cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2011-11-22T08:57:02Z [Term] id: GO:0086067 name: AV node cell to bundle of His cell communication def: "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cell to bundle of His cell communication" EXACT [] is_a: GO:0086065 ! cell communication involved in cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2011-11-22T09:11:44Z [Term] id: GO:0086068 name: Purkinje myocyte to ventricular cardiac muscle cell communication def: "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086065 ! cell communication involved in cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2011-11-22T09:14:49Z [Term] id: GO:0086070 name: SA node cell to atrial cardiac muscle cell communication def: "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell communication" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "sinus node cardiomyocyte to atrial cardiomyocyte communication" NARROW [] is_a: GO:0086065 ! cell communication involved in cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: dph creation_date: 2011-11-22T09:32:45Z [Term] id: GO:0089718 name: amino acid import across plasma membrane alt_id: GO:0043092 alt_id: GO:0044745 alt_id: GO:1902837 def: "The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol." [GOC:krc, PMID:8195186] synonym: "amino acid import into cell" EXACT [] synonym: "amino acid transmembrane import" BROAD [] synonym: "L-amino acid import" BROAD [] synonym: "L-amino acid uptake" NARROW [] is_a: GO:0003333 ! amino acid transmembrane transport is_a: GO:0098739 ! import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:35238 ! has primary input amino-acid zwitterion created_by: jl creation_date: 2012-11-14T14:21:41Z [Term] id: GO:0090009 name: primitive streak formation def: "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] xref: Reactome:R-HSA-9754189 "Germ layer formation at gastrulation" is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004341 ! results in formation of anatomical entity primitive streak relationship: in_taxon NCBITaxon:33511 ! Deuterostomia relationship: part_of GO:0001702 ! gastrulation with mouth forming second relationship: part_of GO:0009948 ! anterior/posterior axis specification relationship: RO:0002297 UBERON:0004341 ! results in formation of anatomical entity primitive streak created_by: tb creation_date: 2009-07-29T10:31:31Z [Term] id: GO:0090063 name: positive regulation of microtubule nucleation def: "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031116 ! positive regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007020 ! positively regulates microtubule nucleation relationship: RO:0002213 GO:0007020 ! positively regulates microtubule nucleation created_by: tb creation_date: 2009-08-12T11:33:09Z [Term] id: GO:0090066 name: regulation of anatomical structure size def: "Any process that modulates the size of an anatomical structure." [GOC:dph, GOC:tb] is_a: GO:0065008 ! regulation of biological quality created_by: tb creation_date: 2009-09-02T11:00:08Z [Term] id: GO:0090068 name: positive regulation of cell cycle process def: "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022402 ! positively regulates cell cycle process relationship: RO:0002213 GO:0022402 ! positively regulates cell cycle process created_by: tb creation_date: 2009-09-09T11:39:52Z [Term] id: GO:0090069 name: regulation of ribosome biogenesis def: "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042254 ! regulates ribosome biogenesis relationship: RO:0002211 GO:0042254 ! regulates ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090070 name: positive regulation of ribosome biogenesis def: "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042254 ! positively regulates ribosome biogenesis relationship: RO:0002213 GO:0042254 ! positively regulates ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090071 name: negative regulation of ribosome biogenesis def: "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042254 ! negatively regulates ribosome biogenesis relationship: RO:0002212 GO:0042254 ! negatively regulates ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090087 name: regulation of peptide transport def: "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015833 ! regulates peptide transport relationship: RO:0002211 GO:0015833 ! regulates peptide transport created_by: tb creation_date: 2009-10-23T11:21:38Z [Term] id: GO:0090091 name: positive regulation of extracellular matrix disassembly def: "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022617 ! positively regulates extracellular matrix disassembly relationship: RO:0002213 GO:0022617 ! positively regulates extracellular matrix disassembly created_by: tb creation_date: 2009-11-04T10:03:25Z [Term] id: GO:0090130 name: tissue migration def: "The process in which the population of cells that make up a tissue undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0032501 ! multicellular organismal process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2009-12-07T03:13:55Z [Term] id: GO:0090131 name: mesenchyme migration def: "The process in which the population of cells that make up a mesenchyme undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090130 ! tissue migration relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0072132 ! mesenchyme morphogenesis created_by: tb creation_date: 2009-12-07T03:15:17Z [Term] id: GO:0090132 name: epithelium migration def: "The process in which the population of cells that make up an epithelium undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090130 ! tissue migration property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2009-12-07T03:19:34Z [Term] id: GO:0090138 name: regulation of actin cytoskeleton organization by cell-cell adhesion def: "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "regulation of actin cytoskeleton organisation by cell-cell adhesion" EXACT [GOC:mah] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: RO:0002211 GO:0030036 ! regulates actin cytoskeleton organization created_by: tb creation_date: 2009-12-08T02:05:00Z [Term] id: GO:0090150 name: establishment of protein localization to membrane def: "The directed movement of a protein to a specific location in a membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "establishment of protein localisation in membrane" EXACT [GOC:mah] synonym: "establishment of protein localization in membrane" EXACT [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0051668 ! localization within membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: RO:0002339 GO:0016020 ! has target end location membrane created_by: tb creation_date: 2009-12-08T03:18:51Z [Term] id: GO:0090162 name: establishment of epithelial cell polarity def: "The specification and formation of anisotropic intracellular organization of an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: BFO:0000066 CL:0000066 ! occurs in epithelial cell relationship: BFO:0000066 CL:0000066 ! occurs in epithelial cell created_by: tb creation_date: 2009-12-08T08:58:27Z [Term] id: GO:0090166 name: Golgi disassembly def: "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus disassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005794 ! results in disassembly of Golgi apparatus relationship: part_of GO:0048313 ! Golgi inheritance relationship: RO:0002590 GO:0005794 ! results in disassembly of Golgi apparatus created_by: tb creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090168 name: Golgi reassembly def: "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus reassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:0022607 ! cellular component assembly relationship: part_of GO:0048313 ! Golgi inheritance created_by: tb creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090170 name: regulation of Golgi inheritance def: "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048313 ! regulates Golgi inheritance relationship: RO:0002211 GO:0048313 ! regulates Golgi inheritance created_by: tb creation_date: 2009-12-11T10:21:59Z [Term] id: GO:0090171 name: chondrocyte morphogenesis def: "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002299 CL:0000138 ! results in maturation of chondrocyte relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0002063 ! chondrocyte development relationship: RO:0002299 CL:0000138 ! results in maturation of chondrocyte created_by: tb creation_date: 2009-12-11T10:36:02Z [Term] id: GO:0090174 name: organelle membrane fusion def: "The joining of two lipid bilayers to form a single organelle membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048284 ! organelle fusion is_a: GO:0061025 ! membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: RO:0012008 GO:0031090 ! results in fusion of organelle membrane relationship: RO:0012008 GO:0031090 ! results in fusion of organelle membrane created_by: tb creation_date: 2009-12-11T11:44:58Z [Term] id: GO:0090183 name: regulation of kidney development def: "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001822 ! regulates kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0001822 ! regulates kidney development created_by: tb creation_date: 2009-12-18T10:50:56Z [Term] id: GO:0090184 name: positive regulation of kidney development def: "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "positive regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001822 ! positively regulates kidney development relationship: RO:0002213 GO:0001822 ! positively regulates kidney development created_by: tb creation_date: 2009-12-18T10:52:01Z [Term] id: GO:0090185 name: negative regulation of kidney development def: "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "negative regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001822 ! negatively regulates kidney development relationship: RO:0002212 GO:0001822 ! negatively regulates kidney development created_by: tb creation_date: 2009-12-18T10:58:45Z [Term] id: GO:0090189 name: regulation of branching involved in ureteric bud morphogenesis def: "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:0090183 ! regulation of kidney development is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001658 ! regulates branching involved in ureteric bud morphogenesis relationship: RO:0002211 GO:0001658 ! regulates branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090190 name: positive regulation of branching involved in ureteric bud morphogenesis def: "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001658 ! positively regulates branching involved in ureteric bud morphogenesis relationship: RO:0002213 GO:0001658 ! positively regulates branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090191 name: negative regulation of branching involved in ureteric bud morphogenesis def: "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001658 ! negatively regulates branching involved in ureteric bud morphogenesis relationship: RO:0002212 GO:0001658 ! negatively regulates branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090257 name: regulation of muscle system process def: "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." [GOC:dph, GOC:tb] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003012 ! regulates muscle system process relationship: RO:0002211 GO:0003012 ! regulates muscle system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2010-02-03T11:48:13Z [Term] id: GO:0090273 name: regulation of somatostatin secretion def: "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070253 ! regulates somatostatin secretion relationship: RO:0002211 GO:0070253 ! regulates somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090274 name: positive regulation of somatostatin secretion def: "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070253 ! positively regulates somatostatin secretion relationship: RO:0002213 GO:0070253 ! positively regulates somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090275 name: negative regulation of somatostatin secretion def: "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070253 ! negatively regulates somatostatin secretion relationship: RO:0002212 GO:0070253 ! negatively regulates somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090276 name: regulation of peptide hormone secretion def: "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030072 ! regulates peptide hormone secretion relationship: RO:0002211 GO:0030072 ! regulates peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090277 name: positive regulation of peptide hormone secretion def: "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002793 ! positive regulation of peptide secretion is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030072 ! positively regulates peptide hormone secretion relationship: RO:0002213 GO:0030072 ! positively regulates peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090278 name: negative regulation of peptide hormone secretion def: "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002792 ! negative regulation of peptide secretion is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030072 ! negatively regulates peptide hormone secretion relationship: RO:0002212 GO:0030072 ! negatively regulates peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090299 name: regulation of neural crest formation def: "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014029 ! regulates neural crest formation relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002211 GO:0014029 ! regulates neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090300 name: positive regulation of neural crest formation def: "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb] is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014029 ! positively regulates neural crest formation relationship: RO:0002213 GO:0014029 ! positively regulates neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090301 name: negative regulation of neural crest formation def: "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb] is_a: GO:0010719 ! negative regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014029 ! negatively regulates neural crest formation relationship: RO:0002212 GO:0014029 ! negatively regulates neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090304 name: nucleic acid metabolic process def: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:33696 ! has primary input or output nucleic acid relationship: RO:0004007 CHEBI:33696 ! has primary input or output nucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26133" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27052" xsd:anyURI created_by: tb creation_date: 2010-04-07T10:18:47Z [Term] id: GO:0090316 name: positive regulation of intracellular protein transport def: "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051222 ! positive regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006886 ! positively regulates intracellular protein transport relationship: RO:0002213 GO:0006886 ! positively regulates intracellular protein transport created_by: tb creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090317 name: negative regulation of intracellular protein transport def: "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051224 ! negative regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006886 ! negatively regulates intracellular protein transport relationship: RO:0002212 GO:0006886 ! negatively regulates intracellular protein transport created_by: tb creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090325 name: regulation of locomotion involved in locomotory behavior def: "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050795 ! regulation of behavior intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031987 ! regulates locomotion involved in locomotory behavior relationship: RO:0002211 GO:0031987 ! regulates locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:24:29Z [Term] id: GO:0090326 name: positive regulation of locomotion involved in locomotory behavior def: "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048520 ! positive regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002213 GO:0031987 ! positively regulates locomotion involved in locomotory behavior relationship: RO:0002213 GO:0031987 ! positively regulates locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090327 name: negative regulation of locomotion involved in locomotory behavior def: "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048521 ! negative regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031987 ! negatively regulates locomotion involved in locomotory behavior relationship: RO:0002212 GO:0031987 ! negatively regulates locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090425 name: acinar cell differentiation def: "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." [GOC:dph, GOC:tb] is_a: GO:0002067 ! glandular epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000622 ! results in acquisition of features of acinar cell relationship: RO:0002315 CL:0000622 ! results in acquisition of features of acinar cell created_by: tb creation_date: 2012-05-04T09:24:48Z [Term] id: GO:0090435 name: protein localization to nuclear envelope def: "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." [GOC:tb] synonym: "protein localization in nuclear envelope" EXACT [] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005635 ! has target end location nuclear envelope relationship: RO:0002339 GO:0005635 ! has target end location nuclear envelope created_by: tb creation_date: 2012-07-30T01:50:41Z [Term] id: GO:0090493 name: catecholamine uptake def: "The directed movement of catecholamine into a cell." [GOC:dph, GOC:tb] is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure created_by: tb creation_date: 2012-10-17T11:06:17Z [Term] id: GO:0090496 name: mesenchyme migration involved in limb bud formation def: "The migration of mesenchymal tissue that contributes to the formation of a limb bud." [GOC:dph, GOC:tb] is_a: GO:0090131 ! mesenchyme migration intersection_of: GO:0090131 ! mesenchyme migration intersection_of: part_of GO:0060174 ! limb bud formation relationship: in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of GO:0060174 ! limb bud formation created_by: tb creation_date: 2012-10-17T12:04:20Z [Term] id: GO:0090497 name: mesenchymal cell migration def: "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." [GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0008019 ! results in movement of mesenchymal cell relationship: RO:0002565 CL:0008019 ! results in movement of mesenchymal cell property_value: RO:0002161 NCBITaxon:4890 created_by: tb creation_date: 2012-10-17T12:08:17Z [Term] id: GO:0090596 name: sensory organ morphogenesis def: "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:kmv, ISBN:978-0199210893] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0000020 ! results in morphogenesis of sense organ relationship: part_of GO:0007423 ! sensory organ development relationship: RO:0002298 UBERON:0000020 ! results in morphogenesis of sense organ created_by: tb creation_date: 2014-08-22T13:23:20Z [Term] id: GO:0090598 name: male anatomical structure morphogenesis def: "The processes by which anatomical structures that are only present in the male organism are generated and organized." [GOC:kmv, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0014403 ! results in morphogenesis of male anatomical structure relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0046661 ! male sex differentiation relationship: RO:0002298 UBERON:0014403 ! results in morphogenesis of male anatomical structure property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2014-08-22T13:29:45Z [Term] id: GO:0090685 name: RNA localization to nucleus def: "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." [GOC:mah, PMID:26305931] synonym: "RNA localisation to nucleus" EXACT [GOC:mah] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: RO:0002339 GO:0005634 ! has target end location nucleus relationship: RO:0002339 GO:0005634 ! has target end location nucleus created_by: tb creation_date: 2016-07-19T17:00:49Z [Term] id: GO:0090741 name: pigment granule membrane def: "Any membrane that is part of a pigment granule." [PMID:11294610] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0048770 ! pigment granule relationship: bounding_layer_of GO:0048770 ! pigment granule relationship: part_of GO:0048770 ! pigment granule created_by: tb creation_date: 2017-05-16T22:33:39Z [Term] id: GO:0097014 name: ciliary plasm def: "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." [GOC:BHF, GOC:cilia, GOC:dos, PMID:17895364] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm". synonym: "cilial cytoplasm" RELATED [] synonym: "ciliary cytoplasm" RELATED [] synonym: "cilium cytoplasm" RELATED [] synonym: "cilium plasm" EXACT [] synonym: "microtubule-based flagellar cytoplasm" RELATED [] synonym: "microtubule-based flagellar matrix" NARROW [] synonym: "microtubule-based flagellum cytoplasm" RELATED [] synonym: "microtubule-based flagellum matrix" NARROW [] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005929 ! cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: pr creation_date: 2011-03-23T01:52:31Z [Term] id: GO:0097026 name: dendritic cell dendrite assembly def: "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, PMID:12200351] comment: Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals. synonym: "dendritic extension" BROAD [] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0097511 ! results in assembly of dendritic cell dendrite relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002588 GO:0097511 ! results in assembly of dendritic cell dendrite created_by: pr creation_date: 2011-03-31T04:52:53Z [Term] id: GO:0097028 name: dendritic cell differentiation def: "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:pr] comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'. is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000451 ! results in acquisition of features of dendritic cell relationship: RO:0002315 CL:0000451 ! results in acquisition of features of dendritic cell created_by: pr creation_date: 2011-04-01T10:08:42Z [Term] id: GO:0097048 name: dendritic cell apoptotic process def: "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:BHF, GOC:mtg_apoptosis, PMID:15059845] synonym: "dendritic cell apoptosis" NARROW [] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000451 ! occurs in dendritic cell relationship: BFO:0000066 CL:0000451 ! occurs in dendritic cell created_by: pr creation_date: 2011-05-04T02:18:59Z [Term] id: GO:0097049 name: motor neuron apoptotic process def: "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:BHF, GOC:mtg_apoptosis, PMID:14523086] synonym: "motoneuron apoptosis" EXACT [] synonym: "motor neuron apoptosis" NARROW [] is_a: GO:0051402 ! neuron apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000100 ! occurs in motor neuron relationship: BFO:0000066 CL:0000100 ! occurs in motor neuron property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-05-04T02:21:43Z [Term] id: GO:0097050 name: type B pancreatic cell apoptotic process def: "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF, GOC:mtg_apoptosis, PMID:16087305] synonym: "pancreatic B cell apoptosis" EXACT [] synonym: "pancreatic beta cell apoptosis" EXACT [] synonym: "type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000169 ! occurs in type B pancreatic cell relationship: BFO:0000066 CL:0000169 ! occurs in type B pancreatic cell property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2011-05-04T02:24:38Z [Term] id: GO:0097060 name: synaptic membrane def: "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:BHF, PMID:20410104] subset: goslim_synapse is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0098590 ! plasma membrane region intersection_of: part_of GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0045202 ! synapse created_by: pr creation_date: 2011-06-07T11:22:09Z [Term] id: GO:0097084 name: vascular associated smooth muscle cell development def: "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] synonym: "vascular smooth muscle cell development" EXACT [] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 CL:0000359 ! results in development of vascular associated smooth muscle cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: RO:0002296 CL:0000359 ! results in development of vascular associated smooth muscle cell created_by: pr creation_date: 2011-06-20T04:03:08Z [Term] id: GO:0097094 name: craniofacial suture morphogenesis def: "The process in which any suture between cranial and/or facial bones is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0009198 ! results in morphogenesis of craniofacial suture relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060349 ! bone morphogenesis relationship: part_of GO:1904888 ! cranial skeletal system development relationship: RO:0002298 UBERON:0009198 ! results in morphogenesis of craniofacial suture created_by: pr creation_date: 2011-07-05T02:51:54Z [Term] id: GO:0097095 name: frontonasal suture morphogenesis def: "The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized." [GOC:pr, GOC:sl, PMID:12416537, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] synonym: "nasofrontal suture morphogenesis" EXACT [] is_a: GO:0097094 ! craniofacial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0005404 ! results in morphogenesis of frontonasal suture relationship: RO:0002298 UBERON:0005404 ! results in morphogenesis of frontonasal suture created_by: pr creation_date: 2011-07-05T02:57:46Z [Term] id: GO:0097096 name: facial suture morphogenesis def: "The process in which any suture between facial bones is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] is_a: GO:0097094 ! craniofacial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0009199 ! results in morphogenesis of facial suture relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002298 UBERON:0009199 ! results in morphogenesis of facial suture created_by: pr creation_date: 2011-07-05T03:06:27Z [Term] id: GO:0097097 name: nasal suture morphogenesis def: "The process in which the nasal suture is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] synonym: "internasal suture morphogenesis" EXACT [] is_a: GO:0097096 ! facial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0009203 ! results in morphogenesis of internasal suture relationship: RO:0002298 UBERON:0009203 ! results in morphogenesis of internasal suture created_by: pr creation_date: 2011-07-05T03:09:04Z [Term] id: GO:0097152 name: mesenchymal cell apoptotic process def: "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [CL:0000134, GOC:mtg_apoptosis, GOC:yaf, PMID:18231833] synonym: "mesenchymal cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0008019 ! occurs in mesenchymal cell relationship: BFO:0000066 CL:0008019 ! occurs in mesenchymal cell property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-09-06T02:31:59Z [Term] id: GO:0097186 name: amelogenesis def: "The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage." [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346] synonym: "enamel development" EXACT [] is_a: GO:0042475 ! odontogenesis of dentin-containing tooth is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001752 ! results in formation of anatomical entity enamel relationship: RO:0002297 UBERON:0001752 ! results in formation of anatomical entity enamel property_value: RO:0002161 NCBITaxon:8782 created_by: pr creation_date: 2011-11-21T09:01:24Z [Term] id: GO:0097187 name: dentinogenesis def: "The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin." [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346] synonym: "dentin development" EXACT [] synonym: "dentine development" EXACT [] is_a: GO:0042475 ! odontogenesis of dentin-containing tooth is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0001751 ! results in formation of anatomical entity dentine relationship: RO:0002297 UBERON:0001751 ! results in formation of anatomical entity dentine property_value: RO:0002161 NCBITaxon:8782 created_by: pr creation_date: 2011-11-21T09:04:17Z [Term] id: GO:0097190 name: apoptotic signaling pathway alt_id: GO:0008624 def: "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis] comment: This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways. synonym: "apoptotic signalling pathway" EXACT [GOC:mah] synonym: "induction of apoptosis by extracellular signals" EXACT [] xref: Reactome:R-HSA-193681 "Ceramide signalling" xref: Reactome:R-HSA-204998 "Cell death signalling via NRAGE, NRIF and NADE" xref: Reactome:R-HSA-75157 "FasL/ CD95L signaling" is_a: GO:0007165 ! signal transduction relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: part_of GO:0006915 ! apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-11-23T09:30:23Z [Term] id: GO:0097194 name: execution phase of apoptosis def: "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:mtg_apoptosis, PMID:21760595] synonym: "apoptosis" NARROW [] synonym: "execution phase of apoptotic process" EXACT [] xref: Reactome:R-HSA-75153 "Apoptotic execution phase" is_a: GO:0009987 ! cellular process relationship: has_part GO:0032060 ! bleb assembly relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: part_of GO:0006915 ! apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-11-23T09:45:24Z [Term] id: GO:0097237 name: cellular response to toxic substance def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:pr] is_a: GO:0009636 ! response to toxic substance is_a: GO:0070887 ! cellular response to chemical stimulus created_by: pr creation_date: 2012-02-02T12:23:31Z [Term] id: GO:0097252 name: oligodendrocyte apoptotic process def: "Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons." [CL:0000128, GOC:mtg_apoptosis, GOC:yaf, PMID:16723520] synonym: "oligodendrocyte apoptosis" NARROW [] is_a: GO:0034349 ! glial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000128 ! occurs in oligodendrocyte relationship: BFO:0000066 CL:0000128 ! occurs in oligodendrocyte property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-03-05T10:51:15Z [Term] id: GO:0097254 name: renal tubular secretion def: "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs." [GOC:rph, PMID:25287933, Wikipedia:Renal_secretion#Secretion] is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: pr creation_date: 2012-03-05T02:03:58Z [Term] id: GO:0097272 name: ammonium homeostasis def: "Any biological process involved in the maintenance of an internal steady state of ammonium." [GOC:yaf, PMID:12695560] synonym: "ammonia homeostasis" EXACT [] is_a: GO:0098771 ! inorganic ion homeostasis intersection_of: GO:0048878 ! chemical homeostasis intersection_of: RO:0002332 CHEBI:28938 ! regulates levels of ammonium relationship: RO:0002332 CHEBI:28938 ! regulates levels of ammonium created_by: pr creation_date: 2012-03-22T02:51:22Z [Term] id: GO:0097275 name: intracellular ammonium homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell." [GOC:yaf, PMID:12695560] synonym: "cellular ammonia homeostasis" EXACT [] synonym: "cellular ammonium homeostasis" EXACT [] is_a: GO:0055082 ! intracellular chemical homeostasis is_a: GO:0097272 ! ammonium homeostasis intersection_of: GO:0055082 ! intracellular chemical homeostasis intersection_of: RO:0002332 CHEBI:28938 ! regulates levels of ammonium created_by: pr creation_date: 2012-03-22T02:54:38Z [Term] id: GO:0097284 name: hepatocyte apoptotic process def: "Any apoptotic process in a hepatocyte, the main structural component of the liver." [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020] synonym: "hepatocyte apoptosis" NARROW [] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000182 ! occurs in hepatocyte relationship: BFO:0000066 CL:0000182 ! occurs in hepatocyte property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2012-03-29T10:23:21Z [Term] id: GO:0097355 name: protein localization to heterochromatin def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." [GOC:mah] synonym: "protein localisation to heterochromatin" EXACT [GOC:mah] is_a: GO:0071168 ! protein localization to chromatin intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0000792 ! has target end location heterochromatin relationship: RO:0002339 GO:0000792 ! has target end location heterochromatin created_by: pr creation_date: 2012-07-03T03:19:07Z [Term] id: GO:0097360 name: chorionic trophoblast cell proliferation def: "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population." [CL:0011101, GOC:BHF, PMID:15150278] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0011101 ! acts on population of chorionic trophoblast cell relationship: RO:0012003 CL:0011101 ! acts on population of chorionic trophoblast cell property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2012-07-19T10:17:37Z [Term] id: GO:0097386 name: glial cell projection def: "A prolongation or process extending from a glial cell." [GOC:mc] synonym: "glial process" RELATED [] synonym: "glial projection" RELATED [] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000125 ! glial cell relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000125 ! glial cell created_by: pr creation_date: 2012-10-22T13:55:54Z [Term] id: GO:0097402 name: neuroblast migration def: "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." [CL:0000031, GOC:jc, PMID:15543145] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000031 ! results in movement of neuroblast (sensu Vertebrata) relationship: RO:0002565 CL:0000031 ! results in movement of neuroblast (sensu Vertebrata) property_value: RO:0002161 NCBITaxon:4890 created_by: pr creation_date: 2012-10-29T08:24:37Z [Term] id: GO:0097427 name: microtubule bundle def: "An arrangement of closely apposed microtubules running parallel to each other." [NIF_Subcellular:sao1872343973] synonym: "microtubule fascicle" EXACT [] xref: NIF_Subcellular:sao1872343973 is_a: GO:0110165 ! cellular anatomical structure relationship: has_part GO:0005874 ! microtubule relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005856 ! cytoskeleton created_by: pr creation_date: 2012-11-07T15:01:27Z [Term] id: GO:0097435 name: supramolecular fiber organization alt_id: GO:0043206 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:pr] synonym: "extracellular fibril organisation" NARROW [] synonym: "extracellular fibril organization" NARROW [] synonym: "extracellular fibril organization and biogenesis" NARROW [GOC:mah] synonym: "fibril organisation" RELATED [] synonym: "fibril organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0099512 ! results in organization of supramolecular fiber relationship: RO:0002592 GO:0099512 ! results in organization of supramolecular fiber created_by: pr creation_date: 2012-11-27T15:46:25Z [Term] id: GO:0097454 name: Schwann cell microvillus def: "Small finger-like extension of a Schwann cell that contacts the nodal membrane." [NIF_Subcellular:sao1890444066, PMID:15988042] xref: NIF_Subcellular:sao1890444066 is_a: GO:0005902 ! microvillus is_a: GO:0097386 ! glial cell projection intersection_of: GO:0005902 ! microvillus intersection_of: part_of CL:0002573 ! Schwann cell relationship: part_of CL:0002573 ! Schwann cell created_by: pr creation_date: 2012-12-19T13:01:02Z [Term] id: GO:0097473 name: retinal rod cell apoptotic process def: "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000604, GOC:jc, PMID:17202487] synonym: "rod photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000604 ! occurs in retinal rod cell relationship: BFO:0000066 CL:0000604 ! occurs in retinal rod cell property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2013-03-21T09:44:45Z [Term] id: GO:0097474 name: retinal cone cell apoptotic process def: "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000573, GOC:jc] synonym: "cone photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000573 ! occurs in retinal cone cell relationship: BFO:0000066 CL:0000573 ! occurs in retinal cone cell property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2013-03-21T09:46:22Z [Term] id: GO:0097475 name: motor neuron migration def: "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:yaf, PMID:20711475] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000100 ! results in movement of motor neuron relationship: RO:0002565 CL:0000100 ! results in movement of motor neuron created_by: pr creation_date: 2013-04-23T13:00:46Z [Term] id: GO:0097476 name: spinal cord motor neuron migration def: "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [CL:0011001, GOC:yaf, PMID:20711475] is_a: GO:0097475 ! motor neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0011001 ! results in movement of spinal cord motor neuron relationship: RO:0002565 CL:0011001 ! results in movement of spinal cord motor neuron created_by: pr creation_date: 2013-04-23T13:03:46Z [Term] id: GO:0097511 name: dendritic cell dendrite def: "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, GOC:cjm, PMID:12200351] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000451 ! dendritic cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of CL:0000451 ! dendritic cell created_by: pr creation_date: 2013-10-16T13:02:25Z [Term] id: GO:0097512 name: cardiac myofibril def: "A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:cjm, GOC:devbiol] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: part_of CL:0000746 ! cardiac muscle cell relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of CL:0000746 ! cardiac muscle cell created_by: pr creation_date: 2013-10-16T13:04:58Z [Term] id: GO:0097524 name: sperm plasma membrane def: "A plasma membrane that is part of a sperm cell." [GOC:cjm] is_a: GO:0005886 ! plasma membrane intersection_of: GO:0005886 ! plasma membrane intersection_of: part_of CL:0000019 ! sperm relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of CL:0000019 ! sperm property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: pr creation_date: 2013-10-18T11:31:17Z [Term] id: GO:0097529 name: myeloid leukocyte migration def: "The movement of a myeloid leukocyte within or between different tissues and organs of the body." [GOC:cvs, PMID:22342843, PMID:24157461] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000766 ! results in movement of myeloid leukocyte relationship: RO:0002565 CL:0000766 ! results in movement of myeloid leukocyte created_by: pr creation_date: 2013-11-11T13:59:43Z [Term] id: GO:0097534 name: lymphoid lineage cell migration def: "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." [GOC:pr, PMID:22342843] synonym: "lymphoid lineage restricted progenitor cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000838 ! results in movement of lymphoid lineage restricted progenitor cell relationship: RO:0002565 CL:0000838 ! results in movement of lymphoid lineage restricted progenitor cell property_value: RO:0002161 NCBITaxon:4890 created_by: pr creation_date: 2013-11-28T10:47:15Z [Term] id: GO:0097576 name: vacuole fusion def: "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." [GOC:pr, GOC:vw, Wikipedia:Vacuole] is_a: GO:0007033 ! vacuole organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0009987 ! cellular process intersection_of: RO:0012008 GO:0005773 ! results in fusion of vacuole relationship: RO:0012008 GO:0005773 ! results in fusion of vacuole created_by: pr creation_date: 2014-02-28T09:49:31Z [Term] id: GO:0097708 name: intracellular vesicle def: "Any vesicle that is part of the intracellular region." [GOC:vesicles] is_a: GO:0031982 ! vesicle is_a: GO:0043231 ! intracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005622 ! intracellular anatomical structure created_by: pr creation_date: 2016-03-29T17:39:45Z [Term] id: GO:0097711 name: ciliary basal body-plasma membrane docking def: "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane." [GOC:cilia, PMID:13978319, PMID:23348840, PMID:23530209, PMID:25686250, PMID:26981235] comment: Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella. synonym: "anchoring of the basal body to the plasma membrane" RELATED [] synonym: "ciliary basal body docking" EXACT [] xref: Reactome:R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" is_a: GO:0140056 ! organelle localization by membrane tethering relationship: part_of GO:0060271 ! cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: pr creation_date: 2016-08-05T16:12:33Z [Term] id: GO:0097712 name: vesicle targeting, trans-Golgi to periciliary membrane compartment def: "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:cilia, PMID:20106869, PMID:23351793, PMID:24814148, PMID:26485645] is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi relationship: part_of GO:0060271 ! cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: pr creation_date: 2016-08-05T16:16:28Z [Term] id: GO:0097722 name: sperm motility def: "Any process involved in the controlled movement of a sperm cell." [GOC:cilia, GOC:krc] subset: gocheck_do_not_annotate synonym: "sperm movement" EXACT [] is_a: GO:0022414 ! reproductive process is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: RO:0002565 CL:0000019 ! results in movement of sperm relationship: RO:0002565 CL:0000019 ! results in movement of sperm property_value: RO:0002161 NCBITaxon:4890 created_by: pr creation_date: 2016-09-01T12:00:45Z [Term] id: GO:0097734 name: extracellular exosome biogenesis def: "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:bf, GOC:PARL, PMID:19442504, PMID:25392495] synonym: "exosome assembly or secretion" EXACT [] synonym: "exosome biogenesis" EXACT [] synonym: "exosome production" EXACT [] synonym: "ILV assembly" RELATED [] synonym: "intraluminal vesicle assembly" RELATED [] is_a: GO:0140112 ! extracellular vesicle biogenesis created_by: pr creation_date: 2016-10-03T14:35:25Z [Term] id: GO:0098523 name: neuromuscular junction of myotube def: "A neuromuscular junction in which the target muscle cell is a myotube." [GOC:dos] comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes. is_a: GO:0031594 ! neuromuscular junction intersection_of: GO:0045202 ! synapse intersection_of: overlaps CL:0000100 ! motor neuron intersection_of: overlaps CL:0002372 ! myotube relationship: overlaps CL:0002372 ! myotube created_by: dos creation_date: 2013-10-14T12:05:12Z [Term] id: GO:0098528 name: skeletal muscle fiber differentiation def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." [GOC:dos] is_a: GO:0014902 ! myotube differentiation is_a: GO:0035914 ! skeletal muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0008002 ! results in acquisition of features of skeletal muscle fiber relationship: RO:0002315 CL:0008002 ! results in acquisition of features of skeletal muscle fiber created_by: dos creation_date: 2013-10-15T14:00:34Z [Term] id: GO:0098544 name: maintenance of protein complex location def: "Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away." [GOC:dos] is_a: GO:0051235 ! maintenance of location intersection_of: GO:0051235 ! maintenance of location intersection_of: RO:0004009 GO:0032991 ! has primary input protein-containing complex relationship: RO:0004009 GO:0032991 ! has primary input protein-containing complex created_by: dos creation_date: 2013-11-15T18:20:16Z [Term] id: GO:0098545 name: maintenance of protein complex location in cytoplasm def: "Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere." [GOC:dos] is_a: GO:0051651 ! maintenance of location in cell is_a: GO:0098544 ! maintenance of protein complex location intersection_of: GO:0098544 ! maintenance of protein complex location intersection_of: BFO:0000066 GO:0005737 ! occurs in cytoplasm intersection_of: RO:0004009 GO:0032991 ! has primary input protein-containing complex relationship: BFO:0000066 GO:0005737 ! occurs in cytoplasm created_by: dos creation_date: 2013-11-15T20:49:15Z [Term] id: GO:0098588 name: bounding membrane of organelle def: "The lipid bilayer that forms the outer-most layer of an organelle." [GOC:dos] comment: Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes. is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043226 ! organelle relationship: bounding_layer_of GO:0043226 ! organelle created_by: dos creation_date: 2014-02-26T13:41:31Z [Term] id: GO:0098590 name: plasma membrane region def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos] comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. subset: gocheck_do_not_annotate synonym: "region of plasma membrane" EXACT [] is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0005886 ! plasma membrane created_by: dos creation_date: 2014-03-06T11:55:32Z [Term] id: GO:0098609 name: cell-cell adhesion alt_id: GO:0016337 def: "The attachment of one cell to another cell via adhesion molecules." [GOC:dos] synonym: "single organismal cell-cell adhesion" RELATED [] is_a: GO:0007155 ! cell adhesion created_by: dos creation_date: 2014-04-16T13:40:03Z [Term] id: GO:0098635 name: protein complex involved in cell-cell adhesion def: "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." [GOC:dos] is_a: GO:0098636 ! protein complex involved in cell adhesion intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of_part_of GO:0098609 ! cell-cell adhesion relationship: capable_of_part_of GO:0098609 ! cell-cell adhesion [Term] id: GO:0098636 name: protein complex involved in cell adhesion alt_id: GO:1990307 def: "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." [GOC:dos] synonym: "cell adhesion complex" RELATED [] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of_part_of GO:0007155 ! cell adhesion relationship: capable_of_part_of GO:0007155 ! cell adhesion [Term] id: GO:0098642 name: network-forming collagen trimer def: "A collagen trimer that forms networks." [PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0098645 ! collagen network relationship: part_of GO:0098645 ! collagen network [Term] id: GO:0098643 name: fibrillar collagen def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:20386646, PMID:21421911, PMID:29853175] synonym: "banded collagen fibril" EXACT [] is_a: GO:0098644 ! complex of collagen trimers relationship: part_of GO:0140152 ! collagenous component of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29474" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30146" xsd:anyURI [Term] id: GO:0098644 name: complex of collagen trimers def: "A complex of collagen trimers such as a fibril or collagen network." [GOC:dos] synonym: "Supramolecular aggregate of collagen" EXACT [PMID:19693541] synonym: "Supramolecular collagen assembly" EXACT [PMID:21421911] is_a: GO:0099080 ! supramolecular complex relationship: has_part GO:0005581 ! collagen trimer relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0031012 ! extracellular matrix [Term] id: GO:0098645 name: collagen network def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] is_a: GO:0098644 ! complex of collagen trimers [Term] id: GO:0098655 name: monoatomic cation transmembrane transport alt_id: GO:0099132 def: "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:dos, GOC:vw] synonym: "ATP hydrolysis coupled cation transmembrane transport" NARROW [] synonym: "cation transmembrane transport" BROAD [] is_a: GO:0006812 ! monoatomic cation transport is_a: GO:0034220 ! monoatomic ion transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:23906 ! has primary input monoatomic cation [Term] id: GO:0098657 name: import into cell def: "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dos] synonym: "uptake" BROAD [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005737 ! has target end location cytoplasm intersection_of: RO:0004009 CHEBI:24431 ! has primary input chemical entity relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005737 ! has target end location cytoplasm relationship: RO:0004009 CHEBI:24431 ! has primary input chemical entity [Term] id: GO:0098658 name: inorganic anion import across plasma membrane def: "The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "inorganic anion import into cell" EXACT [] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0099587 ! inorganic ion import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:24834 ! has primary input inorganic anion [Term] id: GO:0098659 name: inorganic cation import across plasma membrane def: "The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "inorganic cation import into cell" EXACT [] is_a: GO:0099587 ! inorganic ion import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:36915 ! has primary input inorganic cation relationship: RO:0004009 CHEBI:36915 ! has primary input inorganic cation [Term] id: GO:0098704 name: carbohydrate import across plasma membrane alt_id: GO:0097319 def: "The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "carbohydrate import into cell" EXACT [] is_a: GO:0034219 ! carbohydrate transmembrane transport is_a: GO:0098739 ! import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:16646 ! has primary input carbohydrate created_by: pr creation_date: 2012-05-31T02:45:02Z [Term] id: GO:0098708 name: D-glucose import across plasma membrane alt_id: GO:0061490 alt_id: GO:1990821 def: "The directed movement of D-glucose from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "glucose import across plasma membrane" EXACT [] synonym: "glucose import into cell" EXACT [] synonym: "high affinity glucose import" NARROW [] is_a: GO:0140271 ! hexose import across plasma membrane is_a: GO:1904659 ! D-glucose transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose created_by: al creation_date: 2012-12-06T14:54:07Z [Term] id: GO:0098719 name: sodium ion import across plasma membrane alt_id: GO:0097369 alt_id: GO:1990118 def: "The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "sodium import" EXACT [] synonym: "sodium ion import" RELATED [] synonym: "sodium ion import into cell" EXACT [] is_a: GO:0035725 ! sodium ion transmembrane transport is_a: GO:0098659 ! inorganic cation import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:29101 ! has primary input sodium(1+) created_by: pr creation_date: 2012-08-03T16:55:52Z [Term] id: GO:0098722 name: asymmetric stem cell division def: "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." [GOC:dos, PMID:18513950] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0017145 ! stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000034 ! has primary input stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0098723 name: skeletal muscle myofibril def: "A myofibril of a skeletal muscle fiber." [GOC:dos] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: part_of CL:0008002 ! skeletal muscle fiber relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of CL:0008002 ! skeletal muscle fiber [Term] id: GO:0098727 name: maintenance of cell number def: "Any process by which the numbers of cells of a particular type or in a tissue are maintained." [GOC:dos] is_a: GO:0032502 ! developmental process [Term] id: GO:0098728 name: germline stem cell asymmetric division def: "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." [GOC:dos] is_a: GO:0042078 ! germ-line stem cell division is_a: GO:0098722 ! asymmetric stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: RO:0004009 CL:0000014 ! has primary input germ line stem cell property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0098739 name: import across plasma membrane def: "The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "uptake" BROAD [] is_a: GO:0055085 ! transmembrane transport is_a: GO:0098657 ! import into cell intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane relationship: RO:0002339 GO:0005829 ! has target end location cytosol relationship: RO:0002342 GO:0005886 ! results in transport across plasma membrane [Term] id: GO:0098751 name: bone cell development def: "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dos] comment: Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development. subset: gocheck_do_not_annotate is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: RO:0002296 CL:0001035 ! results in development of bone cell relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060348 ! bone development relationship: RO:0002296 CL:0001035 ! results in development of bone cell [Term] id: GO:0098754 name: detoxification def: "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:dos] subset: goslim_euk_cellular_processes_ribbon subset: goslim_generic subset: goslim_pombe subset: goslim_prokaryote subset: goslim_prokaryote_ribbon is_a: GO:0008150 ! biological process relationship: part_of GO:0009636 ! response to toxic substance [Term] id: GO:0098771 name: inorganic ion homeostasis def: "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell." [GOC:dos] subset: goslim_pombe is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0042592 ! homeostatic process intersection_of: RO:0002332 CHEBI:36914 ! regulates levels of inorganic ion relationship: RO:0002332 CHEBI:36914 ! regulates levels of inorganic ion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24455" xsd:anyURI [Term] id: GO:0098773 name: skin epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." [GOC:dos] is_a: GO:0008544 ! epidermis development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001003 ! results in development of skin epidermis relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0043588 ! skin development relationship: RO:0002296 UBERON:0001003 ! results in development of skin epidermis [Term] id: GO:0098793 name: presynapse def: "The part of a synapse that is part of the presynaptic cell." [GOC:dos] subset: goslim_synapse synonym: "presynaptic terminal" EXACT [] is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000540 ! neuron relationship: part_of GO:0045202 ! synapse [Term] id: GO:0098794 name: postsynapse def: "The part of a synapse that is part of the post-synaptic cell." [GOC:dos] subset: goslim_synapse is_a: GO:0110165 ! cellular anatomical structure relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of CL:0000000 ! cell relationship: part_of GO:0045202 ! synapse [Term] id: GO:0098796 name: membrane protein complex def: "Any protein complex that is part of a membrane." [GOC:dos] subset: goslim_metagenomics is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0016020 ! membrane relationship: part_of GO:0016020 ! membrane [Term] id: GO:0098797 name: plasma membrane protein complex def: "Any protein complex that is part of the plasma membrane." [GOC:dos] is_a: GO:0098796 ! membrane protein complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0005886 ! plasma membrane [Term] id: GO:0098801 name: regulation of renal system process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system." [GOC:dos] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003014 ! regulates renal system process relationship: RO:0002211 GO:0003014 ! regulates renal system process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 [Term] id: GO:0098813 name: nuclear chromosome segregation def: "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:dos] is_a: GO:0007059 ! chromosome segregation [Term] id: GO:0098840 name: protein transport along microtubule def: "The directed movement of a protein along a microtubule, mediated by motor proteins." [PMID:25987607] synonym: "microtubule-based protein transport" BROAD [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0010970 ! transport along microtubule is_a: GO:0099118 ! microtubule-based protein transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0098858 name: actin-based cell projection def: "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." [PMID:15661519] is_a: GO:0120025 ! plasma membrane bounded cell projection relationship: has_part GO:0005884 ! actin filament [Term] id: GO:0098867 name: intramembranous bone growth def: "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." [PMID:26399686] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0002514 ! results in growth of intramembranous bone relationship: RO:0002343 UBERON:0002514 ! results in growth of intramembranous bone [Term] id: GO:0098868 name: bone growth def: "The increase in size or mass of a bone that contributes to the shaping of that bone." [GOC:dos] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: RO:0002343 UBERON:0001474 ! results in growth of bone element relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060348 ! bone development relationship: RO:0002343 UBERON:0001474 ! results in growth of bone element [Term] id: GO:0098871 name: postsynaptic actin cytoskeleton def: "The actin cytoskeleton that is part of a postsynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099571 ! postsynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse [Term] id: GO:0098876 name: vesicle-mediated transport to the plasma membrane def: "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." [GOC:dos] is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0051668 ! localization within membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002339 GO:0005886 ! has target end location plasma membrane intersection_of: RO:0002608 GO:0031982 ! process has causal agent vesicle relationship: ends_with GO:0006887 ! exocytosis relationship: RO:0002339 GO:0005886 ! has target end location plasma membrane [Term] id: GO:0098883 name: synapse pruning def: "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." [GOC:dos, PMID:12062020, PMID:18083105, PMID:22632716, PMID:29844190] subset: goslim_synapse synonym: "synapse clearance" EXACT [GOC:aruk, GOC:bc, PMID:22632716] synonym: "synapse disassembly" EXACT syngo_official_label [PMID:12062020] synonym: "synapse elimination" EXACT [GOC:aruk, GOC:bc, PMID:18083105, PMID:29844190] synonym: "synapse removal" EXACT [GOC:aruk, GOC:bc, PMID:22632716] is_a: GO:0050808 ! synapse organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0045202 ! results in disassembly of synapse relationship: RO:0002590 GO:0045202 ! results in disassembly of synapse [Term] id: GO:0098900 name: regulation of action potential def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] comment: The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term. is_a: GO:0042391 ! regulation of membrane potential is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0001508 ! regulates action potential relationship: RO:0002211 GO:0001508 ! regulates action potential property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0098901 name: regulation of cardiac muscle cell action potential def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086001 ! regulates cardiac muscle cell action potential relationship: RO:0002211 GO:0086001 ! regulates cardiac muscle cell action potential property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0098904 name: regulation of AV node cell action potential def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "regulation of AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086016 ! regulates AV node cell action potential relationship: RO:0002211 GO:0086016 ! regulates AV node cell action potential property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098906 name: regulation of Purkinje myocyte action potential def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086017 ! regulates Purkinje myocyte action potential relationship: RO:0002211 GO:0086017 ! regulates Purkinje myocyte action potential property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098907 name: regulation of SA node cell action potential def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of SA node cardiac muscle cell action potential" EXACT [] synonym: "regulation of SAN cardiac muscle cell action potential" EXACT [] synonym: "regulation of sinoatrial node cardiac muscle cell action potential" EXACT [] synonym: "regulation of sinus node cardiac muscle cell action potential" NARROW [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0086015 ! regulates SA node cell action potential relationship: RO:0002211 GO:0086015 ! regulates SA node cell action potential property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0098908 name: regulation of neuronal action potential def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dph, GOC:isa_complete, GOC:tb] synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] is_a: GO:0051969 ! regulation of transmission of nerve impulse is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0019228 ! regulates neuronal action potential relationship: RO:0002211 GO:0019228 ! regulates neuronal action potential [Term] id: GO:0098916 name: anterograde trans-synaptic signaling def: "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098793 ! has start location presynapse intersection_of: RO:0002232 GO:0098794 ! has end location postsynapse relationship: RO:0002231 GO:0098793 ! has start location presynapse relationship: RO:0002232 GO:0098794 ! has end location postsynapse [Term] id: GO:0098917 name: retrograde trans-synaptic signaling def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse relationship: RO:0002231 GO:0098794 ! has start location postsynapse relationship: RO:0002232 GO:0098793 ! has end location presynapse [Term] id: GO:0098920 name: retrograde trans-synaptic signaling by lipid def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." [GOC:dos] subset: goslim_synapse is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099541 ! trans-synaptic signaling by lipid intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse intersection_of: RO:0002608 CHEBI:18059 ! process has causal agent lipid [Term] id: GO:0098926 name: postsynaptic signal transduction def: "Signal transduction in which the initial step occurs in a postsynapse." [GOC:dos] subset: goslim_synapse synonym: "postsynaptic signaling pathway" EXACT syngo_official_label [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0099536 ! synaptic signaling relationship: RO:0002231 GO:0098794 ! has start location postsynapse [Term] id: GO:0098928 name: presynaptic signal transduction def: "Signal transduction in which the initial step occurs in a presynapse." [GOC:dos] subset: goslim_synapse synonym: "presynaptic signaling pathway" EXACT syngo_official_label [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: RO:0002231 GO:0098793 ! has start location presynapse relationship: RO:0002231 GO:0098793 ! has start location presynapse [Term] id: GO:0098930 name: axonal transport def: "The directed movement of organelles or molecules along microtubules in axons." [ISBN:0815316194] subset: goslim_synapse synonym: "axon cargo transport" EXACT [] synonym: "axoplasmic transport" EXACT [] xref: Wikipedia:Axoplasmic_transport is_a: GO:0008088 ! axo-dendritic transport intersection_of: GO:0046907 ! intracellular transport intersection_of: BFO:0000066 GO:0030424 ! occurs in axon intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule relationship: BFO:0000066 GO:0030424 ! occurs in axon [Term] id: GO:0098974 name: postsynaptic actin cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099188 ! postsynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0098871 ! results in organization of postsynaptic actin cytoskeleton relationship: RO:0002592 GO:0098871 ! results in organization of postsynaptic actin cytoskeleton [Term] id: GO:0098975 name: postsynapse of neuromuscular junction def: "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." [GOC:dos, Wikipedia:Neuromuscular_junction&oldid=723623502] is_a: GO:0098794 ! postsynapse intersection_of: GO:0098794 ! postsynapse intersection_of: part_of CL:0000187 ! muscle cell intersection_of: part_of GO:0031594 ! neuromuscular junction relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000187 ! muscle cell relationship: part_of GO:0031594 ! neuromuscular junction [Term] id: GO:0098981 name: cholinergic synapse def: "A synapse that uses acetylcholine as a neurotransmitter." [GOC:dos] subset: goslim_synapse is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: capable_of GO:0007271 ! synaptic transmission, cholinergic relationship: capable_of GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0098992 name: neuronal dense core vesicle def: "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals." [GOC:dos, ISBN:978-0-07-181001-2, Wikipedia:Neuropeptide&oldid=713905176] subset: goslim_synapse is_a: GO:0031045 ! dense core granule intersection_of: GO:0031045 ! dense core granule intersection_of: part_of CL:0000540 ! neuron relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of CL:0000540 ! neuron [Term] id: GO:0099003 name: vesicle-mediated transport in synapse def: "Any vesicle-mediated transport that occurs in a synapse." [GOC:dos] subset: goslim_synapse is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0099012 name: neuronal dense core vesicle membrane def: "The lipid bilayer surrounding a neuronal dense core vesicle." [GOC:dos] subset: goslim_synapse is_a: GO:0032127 ! dense core granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0098992 ! neuronal dense core vesicle relationship: bounding_layer_of GO:0098992 ! neuronal dense core vesicle relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0098992 ! neuronal dense core vesicle [Term] id: GO:0099014 name: neuronal dense core vesicle organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle." [GOC:dos] is_a: GO:0061109 ! dense core granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0098992 ! results in organization of neuronal dense core vesicle relationship: RO:0002592 GO:0098992 ! results in organization of neuronal dense core vesicle [Term] id: GO:0099054 name: presynapse assembly def: "The aggregation, arrangement and bonding together of a set of components to form a presynapse." [GOC:bf, GOC:dos, GOC:PARL, PMID:24449494] subset: goslim_synapse synonym: "presynapse biogenesis" EXACT [GOC:mah] synonym: "presynaptic terminal assembly" EXACT [PMID:24449494] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099172 ! presynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0098793 ! results in assembly of presynapse relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007416 ! synapse assembly relationship: RO:0002588 GO:0098793 ! results in assembly of presynapse [Term] id: GO:0099068 name: postsynapse assembly def: "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:bf, GOC:dos, GOCL:PARL] synonym: "postsynapse biogenesis" EXACT [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099173 ! postsynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002588 GO:0098794 ! results in assembly of postsynapse relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0007416 ! synapse assembly relationship: RO:0002588 GO:0098794 ! results in assembly of postsynapse [Term] id: GO:0099080 name: supramolecular complex def: "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." [GOC:dos] subset: gocheck_do_not_annotate is_a: GO:0110165 ! cellular anatomical structure [Term] id: GO:0099081 name: supramolecular polymer def: "A polymeric supramolecular structure." [GOC:dos] is_a: GO:0099080 ! supramolecular complex intersection_of: GO:0099080 ! supramolecular complex intersection_of: RO:0000053 PATO:0015006 ! bearer of polymeric relationship: RO:0000053 PATO:0015006 ! bearer of polymeric [Term] id: GO:0099082 name: retrograde trans-synaptic signaling by neuropeptide def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] subset: goslim_synapse is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse intersection_of: RO:0002608 CHEBI:60466 ! process has causal agent peptide zwitterion [Term] id: GO:0099083 name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission def: "Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide is_a: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission intersection_of: RO:0002231 GO:0098794 ! has start location postsynapse intersection_of: RO:0002232 GO:0098793 ! has end location presynapse intersection_of: RO:0002608 CHEBI:60466 ! process has causal agent peptide zwitterion [Term] id: GO:0099098 name: microtubule polymerization based movement def: "The movement of a cellular component as a result of microtubule polymerization." [GOC:cjm, ISBN:0815316194] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: has_part GO:0046785 ! microtubule polymerization relationship: has_part GO:0046785 ! microtubule polymerization relationship: in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0099111 name: microtubule-based transport def: "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule relationship: RO:0002608 GO:0005874 ! process has causal agent microtubule [Term] id: GO:0099112 name: microtubule polymerization based protein transport def: "The transport of a protein driven by polymerization of a microtubule to which it is attached." [GOC:dos, GOC:vw, PMID:11018050] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0007017 ! microtubule-based process is_a: GO:0099118 ! microtubule-based protein transport intersection_of: GO:0046907 ! intracellular transport intersection_of: has_part GO:0046785 ! microtubule polymerization intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: has_part GO:0046785 ! microtubule polymerization [Term] id: GO:0099118 name: microtubule-based protein transport def: "A microtubule-based process that results in the transport of proteins." [GOC:vw] is_a: GO:0015031 ! protein transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002608 GO:0005874 ! process has causal agent microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0099140 name: presynaptic actin cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099187 ! presynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0099143 ! results in organization of presynaptic actin cytoskeleton relationship: RO:0002592 GO:0099143 ! results in organization of presynaptic actin cytoskeleton created_by: dos creation_date: 2017-06-09T18:34:19Z [Term] id: GO:0099143 name: presynaptic actin cytoskeleton def: "The actin cytoskeleton that is part of a presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099569 ! presynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: part_of GO:0098793 ! presynapse created_by: dos creation_date: 2017-06-09T18:36:19Z [Term] id: GO:0099156 name: cell-cell signaling via exosome def: "Cell-cell signaling in which the ligand is carried between cells by an exosome." [GOC:dos, PMID:19837038] synonym: "exosome mediated" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002608 GO:0070062 ! process has causal agent extracellular exosome relationship: RO:0002608 GO:0070062 ! process has causal agent extracellular exosome created_by: dos creation_date: 2017-07-05T16:40:45Z [Term] id: GO:0099157 name: trans-synaptic signaling via exosome def: "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." [GOC:dos, PMID:19837038] subset: goslim_synapse synonym: "exosome mediated transynaptic signalling" EXACT [] synonym: "trans-synaptic signalling via exosome" EXACT [] is_a: GO:0099156 ! cell-cell signaling via exosome is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002608 GO:0070062 ! process has causal agent extracellular exosome created_by: dos creation_date: 2017-07-05T16:49:44Z [Term] id: GO:0099160 name: postsynaptic intermediate filament cytoskeleton def: "The intermediate filament cytoskeleton that is part of a postsynapse." [GOC:dos, PMID:25869803] subset: goslim_synapse is_a: GO:0045111 ! intermediate filament cytoskeleton is_a: GO:0099571 ! postsynaptic cytoskeleton intersection_of: GO:0045111 ! intermediate filament cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse created_by: dos creation_date: 2017-08-28T15:26:08Z [Term] id: GO:0099170 name: postsynaptic modulation of chemical synaptic transmission def: "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." [GOC:dos] subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse created_by: dos creation_date: 2017-09-11T17:09:17Z [Term] id: GO:0099171 name: presynaptic modulation of chemical synaptic transmission def: "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." [GOC:dos] subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse created_by: dos creation_date: 2017-09-11T17:09:31Z [Term] id: GO:0099172 name: presynapse organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." [GOC:dos] subset: goslim_synapse synonym: "presynapse development" EXACT [] synonym: "presynapse morphogenesis" RELATED [GOC:BHF] synonym: "presynapse organisation" EXACT [] synonym: "presynapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0098793 ! results in organization of presynapse relationship: part_of GO:0050808 ! synapse organization relationship: RO:0002592 GO:0098793 ! results in organization of presynapse [Term] id: GO:0099173 name: postsynapse organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." [GOC:dos] subset: goslim_synapse synonym: "postsynapse development" EXACT [] synonym: "postsynapse morphogenesis" RELATED [GOC:BHF] synonym: "postsynapse organisation" EXACT [] synonym: "postsynapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0098794 ! results in organization of postsynapse relationship: part_of GO:0050808 ! synapse organization relationship: RO:0002592 GO:0098794 ! results in organization of postsynapse [Term] id: GO:0099174 name: regulation of presynapse organization def: "Any process that modulates the physical form of a presynapse." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of presynapse organisation" EXACT [GOC:mah] synonym: "regulation of presynapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of presynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099172 ! regulates presynapse organization relationship: RO:0002211 GO:0099172 ! regulates presynapse organization [Term] id: GO:0099175 name: regulation of postsynapse organization def: "Any process that modulates the physical form of a postsynapse." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of postsynapse organisation" EXACT [GOC:mah] synonym: "regulation of postsynapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of postsynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099173 ! regulates postsynapse organization relationship: RO:0002211 GO:0099173 ! regulates postsynapse organization [Term] id: GO:0099177 name: regulation of trans-synaptic signaling def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." [GOC:dos] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099537 ! regulates trans-synaptic signaling relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0099537 ! regulates trans-synaptic signaling [Term] id: GO:0099182 name: presynaptic intermediate filament cytoskeleton def: "The intermediate filament cytoskeleton that is part of a presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0045111 ! intermediate filament cytoskeleton is_a: GO:0099569 ! presynaptic cytoskeleton intersection_of: GO:0045111 ! intermediate filament cytoskeleton intersection_of: part_of GO:0098793 ! presynapse created_by: dos creation_date: 2017-12-01T18:10:21Z [Term] id: GO:0099185 name: postsynaptic intermediate filament cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0045104 ! intermediate filament cytoskeleton organization is_a: GO:0099188 ! postsynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0099160 ! results in organization of postsynaptic intermediate filament cytoskeleton relationship: RO:0002592 GO:0099160 ! results in organization of postsynaptic intermediate filament cytoskeleton created_by: dos creation_date: 2017-12-20T13:47:30Z [Term] id: GO:0099187 name: presynaptic cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." [GOC:dos] is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0009987 ! cellular process intersection_of: RO:0002592 GO:0099569 ! results in organization of presynaptic cytoskeleton relationship: part_of GO:0099172 ! presynapse organization relationship: RO:0002592 GO:0099569 ! results in organization of presynaptic cytoskeleton created_by: dos creation_date: 2017-12-20T15:05:34Z [Term] id: GO:0099188 name: postsynaptic cytoskeleton organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0099571 ! results in organization of postsynaptic cytoskeleton relationship: part_of GO:0099173 ! postsynapse organization relationship: RO:0002592 GO:0099571 ! results in organization of postsynaptic cytoskeleton created_by: dos creation_date: 2017-12-20T15:06:57Z [Term] id: GO:0099500 name: vesicle fusion to plasma membrane def: "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." [GOC:aruk, GOC:bc, ISBN:0071120009, PMID:18618940] is_a: GO:0006906 ! vesicle fusion is_a: GO:0140029 ! exocytic process intersection_of: GO:0061025 ! membrane fusion intersection_of: part_of GO:0006887 ! exocytosis intersection_of: RO:0012008 GO:0012506 ! results in fusion of vesicle membrane intersection_of: RO:0012008 GO:0098590 ! results in fusion of plasma membrane region relationship: RO:0012008 GO:0098590 ! results in fusion of plasma membrane region [Term] id: GO:0099501 name: exocytic vesicle membrane def: "The lipid bilayer surrounding an exocytic vesicle." [GOC:dos] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030658 ! transport vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0070382 ! exocytic vesicle relationship: bounding_layer_of GO:0070382 ! exocytic vesicle relationship: part_of GO:0070382 ! exocytic vesicle [Term] id: GO:0099503 name: secretory vesicle def: "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." [GOC:dos] subset: goslim_drosophila is_a: GO:0031410 ! cytoplasmic vesicle intersection_of: GO:0031982 ! vesicle intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane relationship: capable_of GO:0099500 ! vesicle fusion to plasma membrane [Term] id: GO:0099512 name: supramolecular fiber alt_id: GO:0043205 def: "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:dos] synonym: "fibril" RELATED [] is_a: GO:0099081 ! supramolecular polymer intersection_of: GO:0099080 ! supramolecular complex intersection_of: RO:0000053 PATO:0002309 ! bearer of fiber shaped intersection_of: RO:0000053 PATO:0015006 ! bearer of polymeric relationship: RO:0000053 PATO:0002309 ! bearer of fiber shaped [Term] id: GO:0099513 name: polymeric cytoskeletal fiber def: "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." [GOC:dos] is_a: GO:0099512 ! supramolecular fiber intersection_of: GO:0099512 ! supramolecular fiber intersection_of: part_of GO:0005856 ! cytoskeleton intersection_of: RO:0000053 PATO:0015006 ! bearer of polymeric relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0005856 ! cytoskeleton [Term] id: GO:0099515 name: actin filament-based transport def: "The transport of organelles or other particles from one location in the cell to another along actin filaments." [GOC:dos, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0005884 ! results in transport along actin filament relationship: RO:0002341 GO:0005884 ! results in transport along actin filament created_by: tb creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0099518 name: vesicle cytoskeletal trafficking def: "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." [GOC:ecd, GOC:rl] synonym: "cytoskeletal fiber-based vesicle localization" EXACT [GOC:rl] synonym: "vesicle cytoskeletal transport" EXACT [] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: RO:0002341 GO:0099513 ! results in transport along polymeric cytoskeletal fiber intersection_of: RO:0004009 GO:0031982 ! has primary input vesicle [Term] id: GO:0099519 name: dense core granule cytoskeletal transport def: "The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments." [GOC:kmv, PMID:23358451] synonym: "dense core vesicle cytoskeletal trafficking" EXACT [] is_a: GO:0099518 ! vesicle cytoskeletal trafficking is_a: GO:1901950 ! dense core granule transport intersection_of: GO:0046907 ! intracellular transport intersection_of: BFO:0000066 GO:0030424 ! occurs in axon intersection_of: RO:0002341 GO:0099513 ! results in transport along polymeric cytoskeletal fiber intersection_of: RO:0004009 GO:0031045 ! has primary input dense core granule relationship: BFO:0000066 GO:0030424 ! occurs in axon [Term] id: GO:0099522 name: cytosolic region def: "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol." [GOC:dos] subset: gocheck_do_not_annotate synonym: "region of cytosol" EXACT [] is_a: GO:0005829 ! cytosol intersection_of: GO:0005829 ! cytosol intersection_of: part_of GO:0005829 ! cytosol relationship: part_of GO:0005829 ! cytosol [Term] id: GO:0099523 name: presynaptic cytosol def: "The region of the cytosol consisting of all cytosol that is part of the presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0099522 ! cytosolic region intersection_of: GO:0005829 ! cytosol intersection_of: part_of GO:0005829 ! cytosol intersection_of: part_of GO:0098793 ! presynapse relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0098793 ! presynapse [Term] id: GO:0099524 name: postsynaptic cytosol def: "The region of the cytosol consisting of all cytosol that is part of the postsynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0099522 ! cytosolic region intersection_of: GO:0005829 ! cytosol intersection_of: part_of GO:0005829 ! cytosol intersection_of: part_of GO:0098794 ! postsynapse relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0098794 ! postsynapse [Term] id: GO:0099531 name: presynaptic process involved in chemical synaptic transmission def: "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." [GOC:dos] subset: gocheck_obsoletion_candidate subset: goslim_synapse is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: part_of GO:0007268 ! chemical synaptic transmission relationship: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: part_of GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099536 name: synaptic signaling def: "Cell-cell signaling to, from or within a synapse." [GOC:dos] subset: goslim_drosophila subset: goslim_synapse is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0099537 name: trans-synaptic signaling def: "Cell-cell signaling in either direction across the synaptic cleft." [GOC:dos] subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling [Term] id: GO:0099538 name: synaptic signaling via neuropeptide def: "Cell-cell signaling to or from a synapse, mediated by a peptide." [GOC:dos] subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling intersection_of: GO:0099536 ! synaptic signaling intersection_of: RO:0002608 CHEBI:60466 ! process has causal agent peptide zwitterion relationship: RO:0002608 CHEBI:60466 ! process has causal agent peptide zwitterion [Term] id: GO:0099540 name: trans-synaptic signaling by neuropeptide def: "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." [GOC:dos] subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling is_a: GO:0099538 ! synaptic signaling via neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002608 CHEBI:60466 ! process has causal agent peptide zwitterion [Term] id: GO:0099541 name: trans-synaptic signaling by lipid def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." [GOC:dos] subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002608 CHEBI:18059 ! process has causal agent lipid relationship: RO:0002608 CHEBI:18059 ! process has causal agent lipid [Term] id: GO:0099546 name: protein catabolic process, modulating synaptic transmission def: "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." [GOC:dos, PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0099547 name: regulation of translation at synapse, modulating synaptic transmission def: "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0006412 ! regulates translation intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0099550 name: trans-synaptic signaling, modulating synaptic transmission def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0099551 name: trans-synaptic signaling by neuropeptide, modulating synaptic transmission def: "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission intersection_of: RO:0002608 CHEBI:60466 ! process has causal agent peptide zwitterion [Term] id: GO:0099552 name: trans-synaptic signaling by lipid, modulating synaptic transmission def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:21531987] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099541 ! trans-synaptic signaling by lipid is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission intersection_of: RO:0002608 CHEBI:18059 ! process has causal agent lipid [Term] id: GO:0099568 name: cytoplasmic region def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." [GOC:dos] subset: gocheck_do_not_annotate is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0099569 name: presynaptic cytoskeleton def: "The portion of the cytoskeleton contained within the presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: part_of GO:0098793 ! presynapse relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0098793 ! presynapse [Term] id: GO:0099571 name: postsynaptic cytoskeleton def: "The portion of the cytoskeleton contained within the postsynapse." [GOC:dos, PMID:19889835] subset: goslim_synapse is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0098794 ! postsynapse [Term] id: GO:0099574 name: regulation of protein catabolic process at synapse, modulating synaptic transmission def: "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission intersection_of: RO:0002211 GO:0009056 ! regulates catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein [Term] id: GO:0099575 name: regulation of protein catabolic process at presynapse, modulating synaptic transmission def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0099576 name: regulation of protein catabolic process at postsynapse, modulating synaptic transmission def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0099577 name: regulation of translation at presynapse, modulating synaptic transmission def: "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140244 ! regulation of translation at presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0006412 ! regulates translation intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0099578 name: regulation of translation at postsynapse, modulating synaptic transmission def: "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140245 ! regulation of translation at postsynapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0006412 ! regulates translation intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission [Term] id: GO:0099587 name: inorganic ion import across plasma membrane def: "The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "inorganic ion import into cell" EXACT [] is_a: GO:0098739 ! import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:36914 ! has primary input inorganic ion relationship: RO:0004009 CHEBI:36914 ! has primary input inorganic ion [Term] id: GO:0099612 name: protein localization to axon def: "A process in which a protein is transported to or maintained in a location within an axon." [GOC:dos, PMID:26157139] is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0030424 ! has target end location axon relationship: RO:0002339 GO:0030424 ! has target end location axon [Term] id: GO:0099632 name: protein transport within plasma membrane def: "A process in which protein is transported from one region of the plasma membrane to another." [GOC:dos] is_a: GO:0032594 ! protein transport within lipid bilayer intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005886 ! occurs in plasma membrane intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: BFO:0000066 GO:0005886 ! occurs in plasma membrane [Term] id: GO:0099640 name: axo-dendritic protein transport def: "The directed movement of proteins along microtubules in neuron projections." [ISBN:0815316194] subset: goslim_synapse synonym: "axonal protein transport" NARROW [] is_a: GO:0008088 ! axo-dendritic transport is_a: GO:0098840 ! protein transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: BFO:0000066 GO:0043005 ! occurs in neuron projection intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0099641 name: anterograde axonal protein transport def: "The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons." [GOC:dos] subset: goslim_synapse synonym: "anterograde axon cargo transport" BROAD [] is_a: GO:0008089 ! anterograde axonal transport is_a: GO:0099640 ! axo-dendritic protein transport is_a: GO:1905383 ! protein localization to presynapse intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm intersection_of: RO:0002339 GO:0098793 ! has target end location presynapse intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0099642 name: retrograde axonal protein transport def: "The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons." [ISBN:0815316194] subset: goslim_synapse synonym: "retrograde axon cargo transport" BROAD [] is_a: GO:0008090 ! retrograde axonal transport is_a: GO:0099640 ! axo-dendritic protein transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm intersection_of: RO:0002338 GO:0098793 ! has target start location presynapse intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 PR:000000001 ! has primary input protein [Term] id: GO:0099643 name: signal release from synapse def: "Any signal release from a synapse." [GOC:dos] subset: goslim_synapse is_a: GO:0023061 ! signal release intersection_of: GO:0023061 ! signal release intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0099536 ! synaptic signaling [Term] id: GO:0099738 name: cell cortex region def: "The complete extent of cell cortex that underlies some some region of the plasma membrane." [GOC:dos] subset: gocheck_do_not_annotate synonym: "perimembrane region" EXACT [] is_a: GO:0005938 ! cell cortex is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005938 ! cell cortex intersection_of: part_of GO:0005938 ! cell cortex relationship: part_of GO:0005938 ! cell cortex [Term] id: GO:0100001 name: regulation of skeletal muscle contraction by action potential def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol] is_a: GO:0001508 ! action potential is_a: GO:0014819 ! regulation of skeletal muscle contraction intersection_of: GO:0001508 ! action potential intersection_of: RO:0002211 GO:0003009 ! regulates skeletal muscle contraction created_by: cjm creation_date: 2015-04-02T04:13:19Z [Term] id: GO:0101023 name: vascular endothelial cell proliferation def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:23201774] is_a: GO:0001935 ! endothelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000071 ! acts on population of blood vessel endothelial cell relationship: RO:0012003 CL:0000071 ! acts on population of blood vessel endothelial cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0101024 name: mitotic nuclear membrane organization def: "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." [GOC:vw, PMID:15147872] comment: This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown. synonym: "nuclear membrane organization involved in mitotic nuclear division" EXACT [] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: part_of GO:0140014 ! mitotic nuclear division relationship: part_of GO:0140014 ! mitotic nuclear division property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19949" xsd:anyURI [Term] id: GO:0101025 name: nuclear membrane biogenesis def: "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." [GOC:vw] is_a: GO:0044091 ! membrane biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: RO:0004008 GO:0031965 ! has primary output nuclear membrane relationship: part_of GO:0071763 ! nuclear membrane organization relationship: RO:0004008 GO:0031965 ! has primary output nuclear membrane [Term] id: GO:0104004 name: cellular response to environmental stimulus def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus." [GOC:dos] is_a: GO:0051716 ! cellular response to stimulus created_by: dos creation_date: 2017-02-17T16:02:42Z [Term] id: GO:0106027 name: neuron projection organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." [GOC:aruk, GOC:bc, PMID:11585923] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0043005 ! results in organization of neuron projection relationship: RO:0002592 GO:0043005 ! results in organization of neuron projection created_by: hjd creation_date: 2017-06-23T18:30:18Z [Term] id: GO:0106214 name: regulation of vesicle fusion with Golgi apparatus def: "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048280 ! regulates vesicle fusion with Golgi apparatus relationship: RO:0002211 GO:0048280 ! regulates vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:12:22Z [Term] id: GO:0106215 name: negative regulation of vesicle fusion with Golgi apparatus def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031339 ! negative regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048280 ! negatively regulates vesicle fusion with Golgi apparatus relationship: RO:0002212 GO:0048280 ! negatively regulates vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:17:17Z [Term] id: GO:0106216 name: positive regulation of vesicle fusion with Golgi apparatus def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031340 ! positive regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048280 ! positively regulates vesicle fusion with Golgi apparatus relationship: RO:0002213 GO:0048280 ! positively regulates vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:20:59Z [Term] id: GO:0110011 name: regulation of basement membrane organization def: "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." [GOC:ha, PMID:27404358] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071711 ! regulates basement membrane organization relationship: RO:0002211 GO:0071711 ! regulates basement membrane organization created_by: kmv [Term] id: GO:0110020 name: regulation of actomyosin structure organization def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." [GOC:lf, PMID:22790195] is_a: GO:0032956 ! regulation of actin cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031032 ! regulates actomyosin structure organization relationship: RO:0002211 GO:0031032 ! regulates actomyosin structure organization created_by: kmv creation_date: 2017-06-20T19:28:58Z [Term] id: GO:0110021 name: cardiac muscle myoblast proliferation def: "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0051450 ! myoblast proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000513 ! acts on population of cardiac muscle myoblast relationship: RO:0012003 CL:0000513 ! acts on population of cardiac muscle myoblast property_value: RO:0002161 NCBITaxon:4751 created_by: kmv creation_date: 2017-06-29T14:35:24Z [Term] id: GO:0110022 name: regulation of cardiac muscle myoblast proliferation def: "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0110021 ! regulates cardiac muscle myoblast proliferation relationship: RO:0002211 GO:0110021 ! regulates cardiac muscle myoblast proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: kmv creation_date: 2017-06-29T15:11:47Z [Term] id: GO:0110023 name: negative regulation of cardiac muscle myoblast proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000818 ! negative regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0110021 ! negatively regulates cardiac muscle myoblast proliferation relationship: RO:0002212 GO:0110021 ! negatively regulates cardiac muscle myoblast proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: kmv creation_date: 2017-06-29T15:18:30Z [Term] id: GO:0110024 name: positive regulation of cardiac muscle myoblast proliferation def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000288 ! positive regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0110021 ! positively regulates cardiac muscle myoblast proliferation relationship: RO:0002213 GO:0110021 ! positively regulates cardiac muscle myoblast proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: kmv creation_date: 2017-06-29T15:24:16Z [Term] id: GO:0110053 name: regulation of actin filament organization def: "Any process that modulates the frequency, rate or extent of actin filament organization." [GOC:kmv] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007015 ! regulates actin filament organization relationship: RO:0002211 GO:0007015 ! regulates actin filament organization created_by: kmv creation_date: 2017-09-20T19:52:57Z [Term] id: GO:0110057 name: regulation of blood vessel endothelial cell differentiation def: "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060837 ! regulates blood vessel endothelial cell differentiation relationship: RO:0002211 GO:0060837 ! regulates blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:32:09Z [Term] id: GO:0110058 name: positive regulation of blood vessel endothelial cell differentiation def: "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045603 ! positive regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060837 ! positively regulates blood vessel endothelial cell differentiation relationship: RO:0002213 GO:0060837 ! positively regulates blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:38:19Z [Term] id: GO:0110059 name: negative regulation of blood vessel endothelial cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060837 ! negatively regulates blood vessel endothelial cell differentiation relationship: RO:0002212 GO:0060837 ! negatively regulates blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:47:29Z [Term] id: GO:0110077 name: vesicle-mediated intercellular transport def: "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." [GOC:sp, PMID:29328915, PMID:29328916] synonym: "endosomal trafficking" RELATED [] is_a: GO:0010496 ! intercellular transport is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0010496 ! intercellular transport intersection_of: RO:0002608 GO:1903561 ! process has causal agent extracellular vesicle relationship: RO:0002608 GO:1903561 ! process has causal agent extracellular vesicle created_by: kmv creation_date: 2018-01-29T14:46:52Z [Term] id: GO:0110079 name: regulation of placenta blood vessel development def: "Any process that modulates the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060674 ! regulates placenta blood vessel development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002211 GO:0060674 ! regulates placenta blood vessel development created_by: kmv creation_date: 2018-02-01T14:49:12Z [Term] id: GO:0110080 name: positive regulation of placenta blood vessel development def: "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060674 ! positively regulates placenta blood vessel development relationship: RO:0002213 GO:0060674 ! positively regulates placenta blood vessel development created_by: kmv creation_date: 2018-02-01T14:55:30Z [Term] id: GO:0110081 name: negative regulation of placenta blood vessel development def: "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060674 ! negatively regulates placenta blood vessel development relationship: RO:0002212 GO:0060674 ! negatively regulates placenta blood vessel development created_by: kmv creation_date: 2018-02-01T15:01:11Z [Term] id: GO:0110110 name: positive regulation of animal organ morphogenesis def: "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009887 ! positively regulates animal organ morphogenesis relationship: RO:0002213 GO:0009887 ! positively regulates animal organ morphogenesis created_by: kmv creation_date: 2018-07-05T14:10:14Z [Term] id: GO:0110111 name: negative regulation of animal organ morphogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009887 ! negatively regulates animal organ morphogenesis relationship: RO:0002212 GO:0009887 ! negatively regulates animal organ morphogenesis created_by: kmv creation_date: 2018-07-05T14:25:21Z [Term] id: GO:0110116 name: regulation of compound eye photoreceptor cell differentiation def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001751 ! regulates compound eye photoreceptor cell differentiation relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: RO:0002211 GO:0001751 ! regulates compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:08:49Z [Term] id: GO:0110117 name: positive regulation of compound eye photoreceptor cell differentiation def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001751 ! positively regulates compound eye photoreceptor cell differentiation relationship: RO:0002213 GO:0001751 ! positively regulates compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:13:28Z [Term] id: GO:0110118 name: negative regulation of compound eye photoreceptor cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001751 ! negatively regulates compound eye photoreceptor cell differentiation relationship: RO:0002212 GO:0001751 ! negatively regulates compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:15:52Z [Term] id: GO:0110122 name: myotube cell migration def: "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." [GOC:ha, PMID:29122742] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0002372 ! results in movement of myotube relationship: RO:0002565 CL:0002372 ! results in movement of myotube property_value: RO:0002161 NCBITaxon:4890 created_by: kmv creation_date: 2018-08-22T20:58:09Z [Term] id: GO:0110123 name: regulation of myotube cell migration def: "Any process that modulates the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0110122 ! regulates myotube cell migration relationship: RO:0002211 GO:0110122 ! regulates myotube cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: kmv creation_date: 2018-08-22T21:06:53Z [Term] id: GO:0110124 name: positive regulation of myotube cell migration def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0110122 ! positively regulates myotube cell migration relationship: RO:0002213 GO:0110122 ! positively regulates myotube cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: kmv creation_date: 2018-08-22T21:09:38Z [Term] id: GO:0110125 name: negative regulation of myotube cell migration def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0110122 ! negatively regulates myotube cell migration relationship: RO:0002212 GO:0110122 ! negatively regulates myotube cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: kmv creation_date: 2018-08-22T21:12:47Z [Term] id: GO:0110165 name: cellular anatomical entity name: cellular anatomical structure def: "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses." [GOC:kmv] def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "cellular anatomical entity" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure relationship: has_part COB:0000013 ! molecule property_value: editor_note "Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes." xsd:string property_value: editor_note "Overlaps with some cellular components from GO" xsd:string property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28978" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z [Term] id: GO:0120025 name: plasma membrane bounded cell projection def: "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] is_a: GO:0042995 ! cell projection intersection_of: GO:0042995 ! cell projection intersection_of: has_part GO:0098590 ! plasma membrane region relationship: has_part GO:0098590 ! plasma membrane region property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13193" xsd:anyURI created_by: krc creation_date: 2017-03-21T17:26:07Z [Term] id: GO:0120031 name: plasma membrane bounded cell projection assembly def: "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] synonym: "eupodium" NARROW [GOC:krc, GOC:rjd, PMID:10328951, PMID:9096956] is_a: GO:0030031 ! cell projection assembly is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0120025 ! results in assembly of plasma membrane bounded cell projection relationship: RO:0002588 GO:0120025 ! results in assembly of plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-24T23:56:08Z [Term] id: GO:0120032 name: regulation of plasma membrane bounded cell projection assembly def: "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0060491 ! regulation of cell projection assembly is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0120031 ! regulates plasma membrane bounded cell projection assembly relationship: RO:0002211 GO:0120031 ! regulates plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:27:04Z [Term] id: GO:0120033 name: negative regulation of plasma membrane bounded cell projection assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0120031 ! negatively regulates plasma membrane bounded cell projection assembly relationship: RO:0002212 GO:0120031 ! negatively regulates plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:34:31Z [Term] id: GO:0120034 name: positive regulation of plasma membrane bounded cell projection assembly def: "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031346 ! positive regulation of cell projection organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0120031 ! positively regulates plasma membrane bounded cell projection assembly relationship: RO:0002213 GO:0120031 ! positively regulates plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:34:45Z [Term] id: GO:0120035 name: regulation of plasma membrane bounded cell projection organization def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." [GOC:krc] is_a: GO:0031344 ! regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0120036 ! regulates plasma membrane bounded cell projection organization relationship: RO:0002211 GO:0120036 ! regulates plasma membrane bounded cell projection organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T16:02:06Z [Term] id: GO:0120036 name: plasma membrane bounded cell projection organization def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc] is_a: GO:0030030 ! cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: RO:0002592 GO:0120025 ! results in organization of plasma membrane bounded cell projection relationship: RO:0002592 GO:0120025 ! results in organization of plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T16:07:02Z [Term] id: GO:0120039 name: plasma membrane bounded cell projection morphogenesis def: "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." [GOC:krc] is_a: GO:0048858 ! cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 GO:0120025 ! results in morphogenesis of plasma membrane bounded cell projection relationship: RO:0002298 GO:0120025 ! results in morphogenesis of plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-28T23:39:37Z [Term] id: GO:0120111 name: neuron projection cytoplasm def: "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." [GOC:ha] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0043005 ! neuron projection relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0043005 ! neuron projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14472" xsd:anyURI created_by: krc creation_date: 2017-11-01T18:58:12Z [Term] id: GO:0120158 name: positive regulation of collagen catabolic process def: "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:dph, GOC:tb] synonym: "activation of collagen catabolic process" NARROW [GOC:dph, GOC:tb] synonym: "positive regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "up-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010714 ! positive regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030574 ! positively regulates collagen catabolic process relationship: RO:0002213 GO:0030574 ! positively regulates collagen catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15720" xsd:anyURI created_by: krc creation_date: 2018-05-11T16:31:42Z [Term] id: GO:0120178 name: steroid hormone biosynthetic process def: "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:krc, GOC:nln] is_a: GO:0006694 ! steroid biosynthetic process intersection_of: GO:0006694 ! steroid biosynthetic process intersection_of: RO:0004008 CHEBI:26764 ! has primary output steroid hormone relationship: RO:0004008 CHEBI:26764 ! has primary output steroid hormone property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16000" xsd:anyURI created_by: krc creation_date: 2019-05-20T22:34:00Z [Term] id: GO:0120186 name: negative regulation of protein localization to chromatin def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "negative regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071168 ! negatively regulates protein localization to chromatin relationship: RO:0002212 GO:0071168 ! negatively regulates protein localization to chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI created_by: krc creation_date: 2018-07-14T00:19:32Z [Term] id: GO:0120187 name: positive regulation of protein localization to chromatin def: "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "positive regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071168 ! positively regulates protein localization to chromatin relationship: RO:0002213 GO:0071168 ! positively regulates protein localization to chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI created_by: krc creation_date: 2018-07-14T00:21:28Z [Term] id: GO:0120188 name: regulation of bile acid secretion def: "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032782 ! regulates bile acid secretion relationship: RO:0002211 GO:0032782 ! regulates bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:28:58Z [Term] id: GO:0120189 name: positive regulation of bile acid secretion def: "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0032892 ! positive regulation of organic acid transport is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032782 ! positively regulates bile acid secretion relationship: RO:0002213 GO:0032782 ! positively regulates bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:36:17Z [Term] id: GO:0120190 name: negative regulation of bile acid secretion def: "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0032891 ! negative regulation of organic acid transport is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032782 ! negatively regulates bile acid secretion relationship: RO:0002212 GO:0032782 ! negatively regulates bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:38:34Z [Term] id: GO:0120222 name: regulation of blastocyst development def: "Any process that modulates the frequency, rate or extent of blastocyst development." [GOC:krc, PMID:29593216] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001824 ! regulates blastocyst development relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002211 GO:0001824 ! regulates blastocyst development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18871" xsd:anyURI created_by: krc creation_date: 2020-02-17T19:59:20Z [Term] id: GO:0120223 name: larynx morphogenesis def: "The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." [GOC:krc, PMID:28177282] synonym: "laryngeal morphogenesis" EXACT [GOC:krc, PMID:28177282] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001737 ! results in morphogenesis of larynx relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0120224 ! larynx development relationship: RO:0002298 UBERON:0001737 ! results in morphogenesis of larynx property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18924" xsd:anyURI created_by: krc creation_date: 2020-02-22T01:42:04Z [Term] id: GO:0120224 name: larynx development def: "The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." [GOC:krc, PMID:28177282] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001737 ! results in development of larynx relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0060541 ! respiratory system development relationship: RO:0002296 UBERON:0001737 ! results in development of larynx property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18924" xsd:anyURI created_by: krc creation_date: 2020-02-24T17:13:10Z [Term] id: GO:0120229 name: protein localization to motile cilium def: "A process in which a protein is transported to, or maintained in, a location within a motile cilium." [GOC:krc, PMID:27486780] synonym: "protein localization to nonmotile primary cilium" RELATED [] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0031514 ! has target end location motile cilium relationship: RO:0002339 GO:0031514 ! has target end location motile cilium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19588" xsd:anyURI property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2020-06-05T23:43:04Z [Term] id: GO:0120261 name: regulation of heterochromatin organization def: "Any process that modulates the frequency, rate, extent or location of heterochromatin organization." [GOC:krc] is_a: GO:1902275 ! regulation of chromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070828 ! regulates heterochromatin organization relationship: RO:0002211 GO:0070828 ! regulates heterochromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20020" xsd:anyURI created_by: krc creation_date: 2020-09-29T20:00:04Z [Term] id: GO:0120262 name: negative regulation of heterochromatin organization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization." [GOC:krc] synonym: "down regulation of heterochromatin organization" EXACT [] synonym: "down-regulation of heterochromatin organization" EXACT [] synonym: "downregulation of heterochromatin organization" EXACT [] synonym: "inhibition of heterochromatin organization" NARROW [] is_a: GO:0120261 ! regulation of heterochromatin organization is_a: GO:1905268 ! negative regulation of chromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070828 ! negatively regulates heterochromatin organization relationship: RO:0002212 GO:0070828 ! negatively regulates heterochromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20020" xsd:anyURI created_by: krc creation_date: 2020-09-29T20:12:30Z [Term] id: GO:0120263 name: positive regulation of heterochromatin organization def: "Any process that activates or increases the frequency, rate or extent of heterochromatin organization." [GOC:krc] synonym: "activation of heterochromatin organization" NARROW [] synonym: "stimulation of heterochromatin organization" NARROW [] synonym: "up regulation of heterochromatin organization" EXACT [] synonym: "up-regulation of heterochromatin organization" EXACT [] synonym: "upregulation of heterochromatin organization" EXACT [] is_a: GO:0120261 ! regulation of heterochromatin organization is_a: GO:1905269 ! positive regulation of chromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070828 ! positively regulates heterochromatin organization relationship: RO:0002213 GO:0070828 ! positively regulates heterochromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20020" xsd:anyURI created_by: krc creation_date: 2020-09-29T20:19:19Z [Term] id: GO:0120275 name: cerebral blood circulation def: "The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:krc, PMID:25397684] synonym: "cerebrum blood circulation" EXACT [] synonym: "telencephelon blood circulation" EXACT [] is_a: GO:0008015 ! blood circulation intersection_of: GO:0008015 ! blood circulation intersection_of: BFO:0000066 UBERON:0001893 ! occurs in telencephalon relationship: BFO:0000066 UBERON:0001893 ! occurs in telencephalon property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: krc creation_date: 2020-10-20T19:13:51Z [Term] id: GO:0120276 name: regulation of cerebral blood circulation def: "Any process that modulates the frequency, rate or extent of cerebral blood circulation." [GOC:krc, PMID:25397684] synonym: "regulation of cerebrum blood circulation" EXACT [] synonym: "regulation of telencephalon blood circulation" EXACT [] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0120275 ! regulates cerebral blood circulation relationship: RO:0002211 GO:0120275 ! regulates cerebral blood circulation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: krc creation_date: 2020-10-21T06:52:22Z [Term] id: GO:0120277 name: positive regulation of cerebral blood circulation def: "Any process that activates or increases the frequency, rate or extent of cerebral blood circulation." [GOC:krc, PMID:25397684] synonym: "activation of cerebral blood circulation" NARROW [] synonym: "positive regulation of cerebrum blood circulation" EXACT [] synonym: "positive regulation of telencephalon blood circulation" EXACT [] synonym: "up regulation of cerebral blood circulation" EXACT [] synonym: "up-regulation of cerebral blood circulation" EXACT [] synonym: "upregulation of cerebral blood circulation" EXACT [] is_a: GO:0120276 ! regulation of cerebral blood circulation is_a: GO:1903524 ! positive regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0120275 ! positively regulates cerebral blood circulation relationship: RO:0002213 GO:0120275 ! positively regulates cerebral blood circulation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: krc creation_date: 2020-10-21T06:55:42Z [Term] id: GO:0120278 name: negative regulation of cerebral blood circulation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation." [GOC:krc, PMID:25397684] synonym: "down regulation of cerebral blood circulation" EXACT [] synonym: "down-regulation of cerebral blood circulation" EXACT [] synonym: "downregulation of cerebral blood circulation" EXACT [] synonym: "inhibition of cerebral blood circulation" NARROW [] synonym: "negative regulation of cerebrum blood circulation" EXACT [] synonym: "negative regulation of telencephalon blood circulation" EXACT [] is_a: GO:0120276 ! regulation of cerebral blood circulation is_a: GO:1903523 ! negative regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0120275 ! negatively regulates cerebral blood circulation relationship: RO:0002212 GO:0120275 ! negatively regulates cerebral blood circulation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: krc creation_date: 2020-10-21T07:02:05Z [Term] id: GO:0120305 name: regulation of pigmentation def: "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." [GOC:krc] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0043473 ! regulates pigmentation relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0043473 ! regulates pigmentation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20524" xsd:anyURI created_by: krc creation_date: 2021-02-09T19:37:35Z [Term] id: GO:0120316 name: sperm flagellum assembly def: "The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium)." [GOC:krc, PMID:32791035] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0044458 ! motile cilium assembly intersection_of: GO:0044458 ! motile cilium assembly intersection_of: BFO:0000066 CL:0000019 ! occurs in sperm relationship: BFO:0000066 CL:0000019 ! occurs in sperm relationship: part_of GO:0007286 ! spermatid development relationship: part_of GO:0030317 ! flagellated sperm motility property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21361" xsd:anyURI property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2021-04-29T01:27:27Z [Term] id: GO:0120331 name: endothelial tube formation def: "The developmental process pertaining to the initial formation of an endothelial tube." [GOC:sl, PMID:23239824] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0035148 ! tube formation intersection_of: RO:0002297 UBERON:0003915 ! results in formation of anatomical entity endothelial tube relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0061154 ! endothelial tube morphogenesis relationship: RO:0002297 UBERON:0003915 ! results in formation of anatomical entity endothelial tube property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI created_by: krc creation_date: 2022-05-25T16:17:59Z [Term] id: GO:0140001 name: morula formation def: "The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." [PMID:37935903, PMID:38386558, PMID:39361745] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0000085 ! results in formation of anatomical entity morula relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002297 UBERON:0000085 ! results in formation of anatomical entity morula property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29162" xsd:anyURI created_by: pg creation_date: 2024-11-12T09:29:56Z [Term] id: GO:0140013 name: meiotic nuclear division def: "One of the two nuclear divisions that occur as part of the meiotic cell cycle." [PMID:9334324] subset: goslim_generic synonym: "meiosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0051321 ! meiotic cell cycle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI created_by: pg creation_date: 2017-03-23T09:40:00Z [Term] id: GO:0140014 name: mitotic nuclear division def: "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [ISBN:0198547684] subset: goslim_chembl subset: goslim_generic synonym: "mitosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0000278 ! mitotic cell cycle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI created_by: pg creation_date: 2017-03-23T14:44:23Z [Term] id: GO:0140029 name: exocytic process def: "The cellular processes that contribute to exocytosis." [Wikipedia:Exocytosis] subset: gocheck_do_not_annotate is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0006887 ! exocytosis relationship: part_of GO:0006887 ! exocytosis created_by: pg creation_date: 2017-05-15T13:20:45Z [Term] id: GO:0140039 name: cell-cell adhesion in response to extracellular stimulus def: "The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus." [PMID:14996911] is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: part_of GO:0051716 ! cellular response to stimulus relationship: part_of GO:0051716 ! cellular response to stimulus created_by: pg creation_date: 2017-05-24T11:37:30Z [Term] id: GO:0140056 name: organelle localization by membrane tethering def: "The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other." [PMID:27875684] subset: goslim_pombe is_a: GO:0022406 ! membrane docking is_a: GO:0051640 ! organelle localization created_by: pg creation_date: 2017-06-27T09:58:51Z [Term] id: GO:0140096 name: catalytic activity, acting on a protein def: "Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: goslim_prokaryote is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0004009 PR:000000001 ! has primary input protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-14T10:32:59Z [Term] id: GO:0140098 name: catalytic activity, acting on RNA def: "Catalytic activity that acts to modify RNA." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: goslim_prokaryote is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid relationship: RO:0004009 CHEBI:33697 ! has primary input ribonucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14208" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI created_by: pg creation_date: 2017-09-14T12:05:21Z [Term] id: GO:0140101 name: catalytic activity, acting on a tRNA def: "Catalytic activity that acts to modify a tRNA." [GOC:molecular_function_refactoring, GOC:pdt] comment: Note that this term excludes activities for which a charged tRNA acts as an amino acid donor. is_a: GO:0140098 ! catalytic activity, acting on RNA intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:17843 ! has primary input transfer RNA relationship: RO:0004009 CHEBI:17843 ! has primary input transfer RNA property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25516" xsd:anyURI created_by: pg creation_date: 2017-09-15T18:41:41Z [Term] id: GO:0140103 name: catalytic activity, acting on a glycoprotein def: "Catalysis of a biochemical reaction in which one of the substrates is a glycoprotein." [GOC:molecular_function_refactoring, GOC:pdt] is_a: GO:0140096 ! catalytic activity, acting on a protein intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-15T19:27:54Z [Term] id: GO:0140112 name: extracellular vesicle biogenesis def: "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content." [PMID:28736435] synonym: "extracellular vesicle assembly" EXACT [] is_a: GO:0044085 ! cellular component biogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14256" xsd:anyURI created_by: pg creation_date: 2017-10-23T11:53:42Z [Term] id: GO:0140115 name: export across plasma membrane def: "The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:pg] synonym: "efflux" BROAD [] is_a: GO:0055085 ! transmembrane transport is_a: GO:0140352 ! export from cell intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane relationship: RO:0002338 GO:0005829 ! has target start location cytosol relationship: RO:0002342 GO:0005886 ! results in transport across plasma membrane created_by: pg creation_date: 2017-10-24T14:38:16Z [Term] id: GO:0140139 name: solid phase of basement membrane def: "The solid compartment of the basement membrane ECM, including a specific subset of basement membrane collagens and basement membrane glycoproteins like laminins or nidogens." [PMID:33972551] is_a: GO:0030312 ! external encapsulating structure relationship: part_of GO:0005604 ! basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29504" xsd:anyURI created_by: pg creation_date: 2025-03-20T11:44:22Z [Term] id: GO:0140143 name: collagenous component of basement membrane def: "Collagenous component of basement membrane ECMs, including collagen IV and other types of collagen specifically expressed in basement membrane." [PMID:21123617, PMID:21421915, PMID:28040522, PMID:28324731, PMID:31387942, PMID:39223427] is_a: GO:0030312 ! external encapsulating structure relationship: part_of GO:0140139 ! solid phase of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29472" xsd:anyURI created_by: pg creation_date: 2025-03-20T11:47:59Z [Term] id: GO:0140151 name: solid phase of interstitial matrix def: "The solid compartment of the interstitial matrix, including interstitial collagens such as fibrillar and fibril-associated collagens and non-collagenous glycoproteins like fibronectin and elastin." [PMID:3284468, PMID:34807416] is_a: GO:0030312 ! external encapsulating structure relationship: part_of GO:0005614 ! interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29505" xsd:anyURI created_by: pg creation_date: 2025-03-20T11:44:22Z [Term] id: GO:0140152 name: collagenous component of interstitial matrix def: "Main components of the interstitial matrix solid phase, including fibrillar and fibril-associated collagens." [PMID:12064927, PMID:17550969, PMID:21421911, PMID:28101870, PMID:39223427] is_a: GO:0030312 ! external encapsulating structure relationship: part_of GO:0140151 ! solid phase of interstitial matrix property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29473" xsd:anyURI created_by: pg creation_date: 2025-03-20T11:47:59Z [Term] id: GO:0140154 name: chicken-wire-like collagen network def: "Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane." [PMID:21421911, PMID:21421915, PMID:31387942] is_a: GO:0098645 ! collagen network relationship: part_of GO:0140143 ! collagenous component of basement membrane property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29401" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/30149" xsd:anyURI created_by: pg creation_date: 2025-03-26T06:42:53Z [Term] id: GO:0140157 name: ammonium import across plasma membrane def: "The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol." [GOC:vw, PMID:16999738] is_a: GO:0072488 ! ammonium transmembrane transport is_a: GO:0098659 ! inorganic cation import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium created_by: pg creation_date: 2018-01-26T12:39:56Z [Term] id: GO:0140236 name: translation at presynapse def: "Translation that occurs at the presynapse." [PMID:27321671] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI created_by: pg creation_date: 2018-07-13T13:00:33Z [Term] id: GO:0140237 name: translation at presynapse, modulating chemical synaptic transmission def: "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." [PMID:27321671] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140236 ! translation at presynapse intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission relationship: RO:0002211 GO:0007268 ! regulates chemical synaptic transmission property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI created_by: pg creation_date: 2018-07-13T13:07:23Z [Term] id: GO:0140238 name: presynaptic endocytosis def: "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:24719103] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006897 ! endocytosis is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099003 ! vesicle-mediated transport in synapse intersection_of: GO:0006897 ! endocytosis intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse relationship: BFO:0000066 GO:0098793 ! occurs in presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/230" xsd:anyURI created_by: pg creation_date: 2018-07-15T07:33:55Z [Term] id: GO:0140239 name: postsynaptic endocytosis def: "A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:12839988] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006897 ! endocytosis is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099003 ! vesicle-mediated transport in synapse intersection_of: GO:0006897 ! endocytosis intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/230" xsd:anyURI created_by: pg creation_date: 2018-07-15T07:38:27Z [Term] id: GO:0140241 name: translation at synapse def: "Translation that occurs at the synapse." [PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006412 ! translation intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:23:12Z [Term] id: GO:0140242 name: translation at postsynapse def: "Translation that occurs at the postsynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:26:27Z [Term] id: GO:0140243 name: regulation of translation at synapse def: "Any process that regulates translation occurring at the synapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0006412 ! regulates translation relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:26Z [Term] id: GO:0140244 name: regulation of translation at presynapse def: "Any process that regulates translation occurring at the presynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0006412 ! regulates translation relationship: BFO:0000066 GO:0098793 ! occurs in presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:33Z [Term] id: GO:0140245 name: regulation of translation at postsynapse def: "Any process that regulates translation occurring at the postsynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0006412 ! regulates translation relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:54Z [Term] id: GO:0140246 name: protein catabolic process at synapse def: "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0030163 ! protein catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0004009 CHEBI:36080 ! has primary input protein property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:12:51Z [Term] id: GO:0140247 name: protein catabolic process at presynapse def: "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse." [PMID:27764673] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098793 ! occurs in presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:23:49Z [Term] id: GO:0140249 name: protein catabolic process at postsynapse def: "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:25:04Z [Term] id: GO:0140250 name: regulation protein catabolic process at synapse def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse." [PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0045202 ! occurs in synapse intersection_of: RO:0002211 GO:0009056 ! regulates catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0045202 ! occurs in synapse relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0004009 CHEBI:36080 ! has primary input protein property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:34:56Z [Term] id: GO:0140251 name: regulation protein catabolic process at presynapse def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse." [PMID:27764673] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098793 ! occurs in presynapse intersection_of: RO:0002211 GO:0009056 ! regulates catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098793 ! occurs in presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:35:39Z [Term] id: GO:0140252 name: regulation protein catabolic process at postsynapse def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: BFO:0000066 GO:0098794 ! occurs in postsynapse intersection_of: RO:0002211 GO:0009056 ! regulates catabolic process intersection_of: RO:0004009 CHEBI:36080 ! has primary input protein relationship: BFO:0000066 GO:0098794 ! occurs in postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:35:56Z [Term] id: GO:0140253 name: cell-cell fusion def: "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." [Wikipedia:Cell_fusion] synonym: "cell cell fusion" EXACT [] synonym: "cell fusion" BROAD [] is_a: GO:0009987 ! cellular process relationship: has_part GO:0045026 ! plasma membrane fusion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15939" xsd:anyURI created_by: pg creation_date: 2018-08-13T18:38:18Z [Term] id: GO:0140271 name: hexose import across plasma membrane def: "The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol." [PMID:10735857] is_a: GO:0008645 ! hexose transmembrane transport is_a: GO:0098704 ! carbohydrate import across plasma membrane intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:18133 ! has primary input hexose created_by: pg creation_date: 2018-10-01T08:49:49Z [Term] id: GO:0140318 name: protein transporter activity def: "Directly binding to a specific protein and delivering it to a specific cellular location." [PMID:18706423] comment: Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation. synonym: "protein carrier activity" RELATED [] synonym: "protein transport chaperone" RELATED [] xref: Reactome:R-HSA-2248891 "M6PR transports activated ARSA to the lysosome" xref: Reactome:R-HSA-9662747 "iRHOM2 transports ADAM17 from ER to the Golgi-network" xref: Reactome:R-HSA-9662818 "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0004009 PR:000000001 ! has primary input protein relationship: RO:0004009 PR:000000001 ! has primary input protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17073" xsd:anyURI created_by: pg creation_date: 2019-04-01T10:41:38Z [Term] id: GO:0140352 name: export from cell def: "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." [GOC:pg] synonym: "efflux" BROAD [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region relationship: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure relationship: RO:0002339 GO:0005576 ! has target end location extracellular region created_by: pg creation_date: 2019-05-22T11:20:45Z [Term] id: GO:0140353 name: lipid export from cell def: "The directed movement of a lipid from a cell, into the extracellular region." [GOC:pg] synonym: "lipid efflux" BROAD [] is_a: GO:0006869 ! lipid transport is_a: GO:0140352 ! export from cell intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005622 ! has target start location intracellular anatomical structure intersection_of: RO:0002339 GO:0005576 ! has target end location extracellular region intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid created_by: pg creation_date: 2019-05-22T11:33:07Z [Term] id: GO:0140354 name: lipid import into cell def: "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:pg] synonym: "lipid uptake" BROAD [] is_a: GO:0006869 ! lipid transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid relationship: RO:0002338 GO:0005576 ! has target start location extracellular region relationship: RO:0002339 GO:0005622 ! has target end location intracellular anatomical structure created_by: pg creation_date: 2019-05-22T11:38:15Z [Term] id: GO:0140513 name: nuclear protein-containing complex def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." [GOC:pg] subset: gocheck_do_not_annotate synonym: "nuclear complex" EXACT [] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0005634 ! nucleus relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005634 ! nucleus created_by: pg creation_date: 2020-09-09T05:12:38Z [Term] id: GO:0140572 name: vacuole fission def: "The division of a vacuole within a cell to form two or more separate vacuoles." [PMID:19643199] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: results_in_fission_of GO:0005773 ! vacuole relationship: results_in_fission_of GO:0005773 ! vacuole property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20639" xsd:anyURI created_by: pg creation_date: 2021-01-04T10:17:58Z [Term] id: GO:0140640 name: catalytic activity, acting on a nucleic acid def: "Catalytic activity that acts to modify a nucleic acid." [GOC:pg] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: RO:0004009 CHEBI:33696 ! has primary input nucleic acid relationship: RO:0004009 CHEBI:33696 ! has primary input nucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21402" xsd:anyURI created_by: pg creation_date: 2021-05-11T06:31:07Z [Term] id: GO:0140694 name: membraneless organelle assembly def: "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." [PMID:28225081] synonym: "non-membrane-bounded organelle assembly" EXACT [] synonym: "non-membrane-bounded organelle formation" EXACT [] synonym: "non-membrane-enclosed organelle assembly" EXACT [] synonym: "non-membrane-enclosed organelle formation" EXACT [] is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0043228 ! results in assembly of membraneless organelle relationship: RO:0002588 GO:0043228 ! results in assembly of membraneless organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21939" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29106" xsd:anyURI created_by: pg creation_date: 2021-08-09T15:30:06Z [Term] id: GO:0140734 name: ammonium excretion def: "The elimination of ammonium ions from an excretory cell." [PMID:25740900] synonym: "ammonia excretion" RELATED [] is_a: GO:0007588 ! excretion intersection_of: GO:0007588 ! excretion intersection_of: RO:0004009 CHEBI:28938 ! has primary input ammonium relationship: RO:0004009 CHEBI:28938 ! has primary input ammonium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: pg creation_date: 2021-11-24T17:55:51Z [Term] id: GO:0140820 name: cytosol to Golgi apparatus transport def: "The directed movement of substances from the cytosol into the Golgi apparatus of a cell." [PMID:28373556] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0002338 GO:0005829 ! has target start location cytosol intersection_of: RO:0002339 GO:0005794 ! has target end location Golgi apparatus intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane relationship: RO:0002338 GO:0005829 ! has target start location cytosol relationship: RO:0002339 GO:0005794 ! has target end location Golgi apparatus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21524" xsd:anyURI created_by: pg creation_date: 2022-05-16T06:59:22Z [Term] id: GO:0140961 name: cellular detoxification of metal ion def: "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion." [PMID:26729300, PMID:33046888, PMID:34442707] synonym: "cellular detoxification of metal cation" EXACT [] is_a: GO:0061687 ! detoxification of inorganic compound is_a: GO:1990748 ! cellular detoxification intersection_of: GO:1990748 ! cellular detoxification intersection_of: RO:0004009 CHEBI:25213 ! has primary input metal cation relationship: RO:0004009 CHEBI:25213 ! has primary input metal cation created_by: pg creation_date: 2022-12-07T15:35:18Z [Term] id: GO:0140962 name: multicellular organismal-level chemical homeostasis def: "A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell." [GOC:curators] synonym: "multicellular organism level chemical homeostasis" EXACT [] synonym: "organismal level chemical homeostasis" EXACT [] is_a: GO:0048871 ! multicellular organismal-level homeostasis is_a: GO:0048878 ! chemical homeostasis intersection_of: GO:0048871 ! multicellular organismal-level homeostasis intersection_of: RO:0002332 CHEBI:24431 ! regulates levels of chemical entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24554" xsd:anyURI property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: pg creation_date: 2022-12-12T09:11:06Z [Term] id: GO:0141187 name: nucleic acid biosynthetic process def: "The biosynthetic process resulting in the formation of a nucleic acid." [GOC:dph, GOC:tb] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:33696 ! has primary output nucleic acid relationship: RO:0004008 CHEBI:33696 ! has primary output nucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27408" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27633" xsd:anyURI created_by: pg creation_date: 2024-03-25T07:33:40Z [Term] id: GO:0141188 name: nucleic acid catabolic process def: "The cellular DNA metabolic process resulting in the breakdown of a nucleic acid." [GOC:curators] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0034655 ! nucleobase-containing compound catabolic process is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:33696 ! has primary input nucleic acid relationship: RO:0004009 CHEBI:33696 ! has primary input nucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27408" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27633" xsd:anyURI created_by: pg creation_date: 2024-03-25T07:35:06Z [Term] id: GO:0150052 name: regulation of postsynapse assembly def: "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:aruk, GOC:bc, PMID:16394100, PMID:16672654, PMID:28185854] subset: goslim_synapse is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099175 ! regulation of postsynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099068 ! regulates postsynapse assembly relationship: RO:0002211 GO:0099068 ! regulates postsynapse assembly created_by: bc creation_date: 2018-05-08T16:38:55Z [Term] id: GO:0150063 name: visual system development def: "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways." [GOC:aruk, GOC:bc, GOC:krc, PMID:15004427, PMID:20647017, PMID:22632727] synonym: "optic pathway development" RELATED [] synonym: "visual pathway development" RELATED [] is_a: GO:0048880 ! sensory system development created_by: bc creation_date: 2018-07-23T10:31:58Z [Term] id: GO:0150076 name: neuroinflammatory response def: "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] synonym: "nerve tissue inflammatory response" EXACT [] synonym: "nervous tissue inflammatory response" EXACT [] synonym: "neural tissue inflammatory response" EXACT [] is_a: GO:0006954 ! inflammatory response created_by: bc creation_date: 2018-07-26T12:25:34Z [Term] id: GO:0150077 name: regulation of neuroinflammatory response def: "Any process that modulates the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0150076 ! regulates neuroinflammatory response relationship: RO:0002211 GO:0150076 ! regulates neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:32:18Z [Term] id: GO:0150078 name: positive regulation of neuroinflammatory response def: "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc] is_a: GO:0050729 ! positive regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0150076 ! positively regulates neuroinflammatory response relationship: RO:0002213 GO:0150076 ! positively regulates neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:35:50Z [Term] id: GO:0150079 name: negative regulation of neuroinflammatory response def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:11099416, PMID:18164423] is_a: GO:0050728 ! negative regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0150076 ! negatively regulates neuroinflammatory response relationship: RO:0002212 GO:0150076 ! negatively regulates neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:38:08Z [Term] id: GO:0150098 name: glial cell-neuron signaling def: "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum." [GOC:aruk, GOC:bc, PMID:14980203, PMID:16144764, PMID:16547515, PMID:18685038, PMID:27788368, PMID:9459440] synonym: "glia-neuron signaling" EXACT [] synonym: "glia-neuron signalling" EXACT [] synonym: "glia-neurone signaling" EXACT [] synonym: "glia-neurone signalling" EXACT [] synonym: "glial cell- neuron signalling" EXACT [] synonym: "glial cell-neurone signalling" EXACT [] synonym: "glial cell-neurone singaling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000125 ! has start location glial cell intersection_of: RO:0002232 CL:0000540 ! has end location neuron relationship: RO:0002231 CL:0000125 ! has start location glial cell relationship: RO:0002232 CL:0000540 ! has end location neuron created_by: bc creation_date: 2018-12-17T12:28:09Z [Term] id: GO:0150099 name: neuron-glial cell signaling def: "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine." [GOC:aruk, GOC:bc, PMID:10195197, PMID:10196584, PMID:10377338, PMID:10493741, PMID:11356870, PMID:11399439, PMID:15252819, PMID:27788368] synonym: "neuron-glia signaling" EXACT [] synonym: "neuron-glia signalling" EXACT [] synonym: "neuron-glial cell signalling" EXACT [] synonym: "neurone-glia signaling" EXACT [] synonym: "neurone-glia signalling" EXACT [] synonym: "neurone-glial cell signaling" EXACT [] synonym: "neurone-glial cell signalling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: RO:0002231 CL:0000540 ! has start location neuron intersection_of: RO:0002232 CL:0000125 ! has end location glial cell relationship: RO:0002231 CL:0000540 ! has start location neuron relationship: RO:0002232 CL:0000125 ! has end location glial cell created_by: bc creation_date: 2018-12-17T12:30:12Z [Term] id: GO:0150105 name: protein localization to cell-cell junction def: "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005911 ! has target end location cell-cell junction relationship: RO:0002339 GO:0005911 ! has target end location cell-cell junction created_by: bc creation_date: 2019-06-11T11:00:18Z [Term] id: GO:0150106 name: regulation of protein localization to cell-cell junction def: "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0150105 ! regulates protein localization to cell-cell junction relationship: RO:0002211 GO:0150105 ! regulates protein localization to cell-cell junction created_by: bc creation_date: 2019-06-11T11:17:15Z [Term] id: GO:0150107 name: positive regulation of protein localization to cell-cell junction def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0150105 ! positively regulates protein localization to cell-cell junction relationship: RO:0002213 GO:0150105 ! positively regulates protein localization to cell-cell junction created_by: bc creation_date: 2019-06-11T11:23:58Z [Term] id: GO:0150111 name: regulation of transepithelial transport def: "Any process that modulates the frequency, rate or extent of transepithelial transport." [GOC:aruk, PMID:27593915] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070633 ! regulates transepithelial transport relationship: RO:0002211 GO:0070633 ! regulates transepithelial transport created_by: bc creation_date: 2019-09-15T07:16:49Z [Term] id: GO:0150119 name: negative regulation of protein localization to cell-cell junction def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc] synonym: "negative regulation of protein localisation to cell-cell junction" EXACT [] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0150105 ! negatively regulates protein localization to cell-cell junction relationship: RO:0002212 GO:0150105 ! negatively regulates protein localization to cell-cell junction created_by: bc creation_date: 2019-11-21T13:53:34Z [Term] id: GO:0150146 name: cell junction disassembly def: "The disaggregation of a cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0030054 ! results in disassembly of cell junction relationship: RO:0002590 GO:0030054 ! results in disassembly of cell junction created_by: bc creation_date: 2019-12-08T11:12:13Z [Term] id: GO:0150147 name: cell-cell junction disassembly def: "The disaggregation of a cell-cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0045216 ! cell-cell junction organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005911 ! results in disassembly of cell-cell junction relationship: RO:0002590 GO:0005911 ! results in disassembly of cell-cell junction created_by: bc creation_date: 2019-12-08T11:16:14Z [Term] id: GO:0160038 name: somatic sensory system development def: "The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain." [PMID:25832476, PMID:31399790] synonym: "somatosensory system development" EXACT [] is_a: GO:0048880 ! sensory system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003942 ! results in development of somatosensory system relationship: RO:0002296 UBERON:0003942 ! results in development of somatosensory system created_by: rynl creation_date: 2022-07-07T16:49:26Z [Term] id: GO:0160043 name: catecholamine secretion, neurotransmission def: "The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter." [PMID:10191060] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: RO:0004009 CHEBI:33567 ! has primary input catecholamine property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23804" xsd:anyURI created_by: rynl creation_date: 2022-08-17T00:36:44Z [Term] id: GO:0160048 name: craniofacial suture closure def: "The process of fusing together the edges of a craniofacial suture." [PMID:33842480] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: RO:0012008 UBERON:0009198 ! results in fusion of craniofacial suture relationship: RO:0012008 UBERON:0009198 ! results in fusion of craniofacial suture property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23213" xsd:anyURI created_by: rynl creation_date: 2022-08-19T23:18:54Z [Term] id: GO:0160093 name: chordate pharynx development def: "The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure." [PMID:23020903] is_a: GO:0060465 ! pharynx development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001042 ! results in development of chordate pharynx relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002296 UBERON:0001042 ! results in development of chordate pharynx property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18285" xsd:anyURI created_by: rynl creation_date: 2023-08-29T21:05:28Z [Term] id: GO:0160307 name: protein biosynthetic process def: "The chemical reactions and pathways resulting in the formation of protein." [Wikipedia:Protein_biosynthesis] synonym: "protein biosynthesis" EXACT [] synonym: "protein synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0019538 ! protein metabolic process is_a: GO:0043604 ! amide biosynthetic process intersection_of: GO:0009059 ! macromolecule biosynthetic process intersection_of: has_part GO:0043039 ! tRNA aminoacylation intersection_of: RO:0004008 PR:000000001 ! has primary output protein relationship: has_part GO:0043039 ! tRNA aminoacylation relationship: part_of GO:0010467 ! gene expression relationship: RO:0004008 PR:000000001 ! has primary output protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15375" xsd:anyURI created_by: rynl creation_date: 2025-09-29T23:16:32Z [Term] id: GO:0170055 name: lipid transmembrane transporter activity def: "Enables the transfer of a lipid from one side of a membrane to the other." [GOC:curators] subset: gocheck_do_not_annotate is_a: GO:0005319 ! lipid transporter activity is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:18059 ! has primary input lipid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27252" xsd:anyURI created_by: ew creation_date: 2024-03-15T18:47:58Z [Term] id: GO:1900015 name: regulation of cytokine production involved in inflammatory response def: "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] is_a: GO:0001817 ! regulation of cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002534 ! regulates cytokine production involved in inflammatory response relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0002534 ! regulates cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:27Z [Term] id: GO:1900016 name: negative regulation of cytokine production involved in inflammatory response def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "down regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] synonym: "down regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] synonym: "negative regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002534 ! negatively regulates cytokine production involved in inflammatory response relationship: RO:0002212 GO:0002534 ! negatively regulates cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:31Z [Term] id: GO:1900017 name: positive regulation of cytokine production involved in inflammatory response def: "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "positive regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] synonym: "up regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] synonym: "up regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002534 ! positively regulates cytokine production involved in inflammatory response relationship: RO:0002213 GO:0002534 ! positively regulates cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:35Z [Term] id: GO:1900073 name: regulation of neuromuscular synaptic transmission def: "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007274 ! regulates neuromuscular synaptic transmission relationship: RO:0002211 GO:0007274 ! regulates neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:10Z [Term] id: GO:1900074 name: negative regulation of neuromuscular synaptic transmission def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] synonym: "down regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "down-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "downregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "inhibition of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] is_a: GO:0050805 ! negative regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007274 ! negatively regulates neuromuscular synaptic transmission relationship: RO:0002212 GO:0007274 ! negatively regulates neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:18Z [Term] id: GO:1900075 name: positive regulation of neuromuscular synaptic transmission def: "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] synonym: "activation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "up regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "up-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "upregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007274 ! positively regulates neuromuscular synaptic transmission relationship: RO:0002213 GO:0007274 ! positively regulates neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:22Z [Term] id: GO:1900076 name: regulation of cellular response to insulin stimulus def: "Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus." [GOC:TermGenie, GOC:yaf] is_a: GO:0048583 ! regulation of response to stimulus is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032869 ! regulates cellular response to insulin stimulus relationship: RO:0002211 GO:0032869 ! regulates cellular response to insulin stimulus property_value: RO:0002161 NCBITaxon:4751 created_by: yaf creation_date: 2012-01-31T11:22:22Z [Term] id: GO:1900077 name: negative regulation of cellular response to insulin stimulus def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus." [GOC:TermGenie, GOC:yaf] synonym: "down regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] synonym: "inhibition of cellular response to insulin stimulus" NARROW [GOC:TermGenie] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:1900076 ! regulation of cellular response to insulin stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032869 ! negatively regulates cellular response to insulin stimulus relationship: RO:0002212 GO:0032869 ! negatively regulates cellular response to insulin stimulus property_value: RO:0002161 NCBITaxon:4751 created_by: yaf creation_date: 2012-01-31T11:23:15Z [Term] id: GO:1900078 name: positive regulation of cellular response to insulin stimulus def: "Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus." [GOC:TermGenie, GOC:yaf] synonym: "activation of cellular response to insulin stimulus" NARROW [GOC:TermGenie] synonym: "up regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:1900076 ! regulation of cellular response to insulin stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032869 ! positively regulates cellular response to insulin stimulus relationship: RO:0002213 GO:0032869 ! positively regulates cellular response to insulin stimulus property_value: RO:0002161 NCBITaxon:4751 created_by: yaf creation_date: 2012-01-31T11:24:30Z [Term] id: GO:1900115 name: extracellular regulation of signal transduction def: "Any regulation of signal transduction that takes place in the extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0009966 ! regulation of signal transduction intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region relationship: BFO:0000066 GO:0005576 ! occurs in extracellular region created_by: bf creation_date: 2012-02-22T10:21:48Z [Term] id: GO:1900116 name: extracellular negative regulation of signal transduction def: "Any negative regulation of signal transduction that takes place in extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "down regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "down-regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "downregulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "extracellular inhibition of signaling pathway" NARROW [GOC:bf] synonym: "inhibition of signal transduction in extracellular region" NARROW [GOC:TermGenie] synonym: "negative regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "negative regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1900115 ! extracellular regulation of signal transduction intersection_of: GO:0009968 ! negative regulation of signal transduction intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region created_by: bf creation_date: 2012-02-22T10:27:56Z [Term] id: GO:1900117 name: regulation of execution phase of apoptosis def: "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097194 ! regulates execution phase of apoptosis relationship: in_taxon NCBITaxon:33154 ! Opisthokonta relationship: RO:0002211 GO:0097194 ! regulates execution phase of apoptosis property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-02-22T11:26:20Z [Term] id: GO:1900118 name: negative regulation of execution phase of apoptosis def: "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "down regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "inhibition of execution phase of apoptosis" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097194 ! negatively regulates execution phase of apoptosis relationship: RO:0002212 GO:0097194 ! negatively regulates execution phase of apoptosis property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-02-22T11:26:24Z [Term] id: GO:1900119 name: positive regulation of execution phase of apoptosis def: "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "activation of execution phase of apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097194 ! positively regulates execution phase of apoptosis relationship: RO:0002213 GO:0097194 ! positively regulates execution phase of apoptosis property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-02-22T11:26:27Z [Term] id: GO:1900125 name: regulation of hyaluronan biosynthetic process def: "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030213 ! regulates hyaluronan biosynthetic process relationship: RO:0002211 GO:0030213 ! regulates hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:21Z [Term] id: GO:1900126 name: negative regulation of hyaluronan biosynthetic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "down regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030213 ! negatively regulates hyaluronan biosynthetic process relationship: RO:0002212 GO:0030213 ! negatively regulates hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:29Z [Term] id: GO:1900127 name: positive regulation of hyaluronan biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "activation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030213 ! positively regulates hyaluronan biosynthetic process relationship: RO:0002213 GO:0030213 ! positively regulates hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:33Z [Term] id: GO:1900141 name: regulation of oligodendrocyte apoptotic process def: "Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] synonym: "regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:0034350 ! regulation of glial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097252 ! regulates oligodendrocyte apoptotic process relationship: RO:0002211 GO:0097252 ! regulates oligodendrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: yaf creation_date: 2012-03-06T10:22:45Z [Term] id: GO:1900142 name: negative regulation of oligodendrocyte apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] synonym: "down regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of oligodendrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:0034351 ! negative regulation of glial cell apoptotic process is_a: GO:1900141 ! regulation of oligodendrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097252 ! negatively regulates oligodendrocyte apoptotic process relationship: RO:0002212 GO:0097252 ! negatively regulates oligodendrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: yaf creation_date: 2012-03-06T10:22:50Z [Term] id: GO:1900143 name: positive regulation of oligodendrocyte apoptotic process def: "Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] synonym: "activation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of oligodendrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034352 ! positive regulation of glial cell apoptotic process is_a: GO:1900141 ! regulation of oligodendrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097252 ! positively regulates oligodendrocyte apoptotic process relationship: RO:0002213 GO:0097252 ! positively regulates oligodendrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: yaf creation_date: 2012-03-06T10:22:54Z [Term] id: GO:1900147 name: regulation of Schwann cell migration def: "Any process that modulates the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0036135 ! regulates Schwann cell migration relationship: RO:0002211 GO:0036135 ! regulates Schwann cell migration created_by: bf creation_date: 2012-03-06T04:14:50Z [Term] id: GO:1900148 name: negative regulation of Schwann cell migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] synonym: "down regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of Schwann cell migration" NARROW [GOC:TermGenie] is_a: GO:1900147 ! regulation of Schwann cell migration is_a: GO:1903976 ! negative regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0036135 ! negatively regulates Schwann cell migration relationship: RO:0002212 GO:0036135 ! negatively regulates Schwann cell migration created_by: bf creation_date: 2012-03-06T04:14:55Z [Term] id: GO:1900149 name: positive regulation of Schwann cell migration def: "Any process that activates or increases the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] synonym: "activation of Schwann cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of Schwann cell migration" EXACT [GOC:TermGenie] is_a: GO:1900147 ! regulation of Schwann cell migration is_a: GO:1903977 ! positive regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0036135 ! positively regulates Schwann cell migration relationship: RO:0002213 GO:0036135 ! positively regulates Schwann cell migration created_by: bf creation_date: 2012-03-06T04:14:58Z [Term] id: GO:1900150 name: regulation of defense response to fungus alt_id: GO:2000072 def: "Any process that modulates the frequency, rate or extent of defense response to fungus." [GOC:dhl, GOC:TermGenie, PMID:22242006] synonym: "regulation of defence response to fungi" EXACT [GOC:TermGenie] synonym: "regulation of defence response to fungus" EXACT [GOC:TermGenie] synonym: "regulation of defense response to fungi" EXACT [GOC:TermGenie] synonym: "regulation of defense response to fungi, incompatible interaction" NARROW [GOC:obol] synonym: "regulation of defense response to fungus, incompatible interaction" NARROW [] synonym: "regulation of resistance response to pathogenic fungi" NARROW [GOC:obol] synonym: "regulation of resistance response to pathogenic fungus" NARROW [GOC:obol] synonym: "regulation of response to pathogenic fungus (incompatible interaction)" NARROW [GOC:obol] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050832 ! regulates defense response to fungus relationship: RO:0002211 GO:0050832 ! regulates defense response to fungus property_value: RO:0002161 NCBITaxon:4895 created_by: dhl creation_date: 2012-03-06T10:00:16Z [Term] id: GO:1900180 name: regulation of protein localization to nucleus def: "Any process that modulates the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034504 ! regulates protein localization to nucleus relationship: RO:0002211 GO:0034504 ! regulates protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:44Z [Term] id: GO:1900181 name: negative regulation of protein localization to nucleus def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in cell nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to nucleus" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034504 ! negatively regulates protein localization to nucleus relationship: RO:0002212 GO:0034504 ! negatively regulates protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:48Z [Term] id: GO:1900182 name: positive regulation of protein localization to nucleus def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "activation of protein localisation to nucleus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in cell nucleus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "activation of protein localization to nucleus" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034504 ! positively regulates protein localization to nucleus relationship: RO:0002213 GO:0034504 ! positively regulates protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:52Z [Term] id: GO:1900193 name: regulation of oocyte maturation def: "Any process that modulates the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001556 ! regulates oocyte maturation relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0001556 ! regulates oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:18Z [Term] id: GO:1900194 name: negative regulation of oocyte maturation def: "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "down regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "inhibition of oocyte maturation" NARROW [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001556 ! negatively regulates oocyte maturation relationship: RO:0002212 GO:0001556 ! negatively regulates oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:27Z [Term] id: GO:1900195 name: positive regulation of oocyte maturation def: "Any process that activates or increases the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "activation of oocyte maturation" NARROW [GOC:TermGenie] synonym: "up regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001556 ! positively regulates oocyte maturation relationship: RO:0002213 GO:0001556 ! positively regulates oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:35Z [Term] id: GO:1900200 name: mesenchymal cell apoptotic process involved in metanephros development def: "Any mesenchymal cell apoptotic process that is involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:0097152 ! mesenchymal cell apoptotic process is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0001656 ! metanephros development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0001656 ! metanephros development created_by: yaf creation_date: 2012-03-21T11:58:05Z [Term] id: GO:1900204 name: apoptotic process involved in metanephric collecting duct development def: "Any apoptotic process that is involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0072205 ! metanephric collecting duct development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072205 ! metanephric collecting duct development created_by: yaf creation_date: 2012-03-21T01:21:32Z [Term] id: GO:1900205 name: apoptotic process involved in metanephric nephron tubule development def: "Any apoptotic process that is involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0072234 ! metanephric nephron tubule development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072234 ! metanephric nephron tubule development created_by: yaf creation_date: 2012-03-21T01:21:45Z [Term] id: GO:1900206 name: regulation of pronephric nephron tubule development def: "Any process that modulates the frequency, rate or extent of pronephric nephron tubule development." [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0039020 ! regulates pronephric nephron tubule development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0039020 ! regulates pronephric nephron tubule development created_by: bf creation_date: 2012-03-22T09:23:13Z [Term] id: GO:1900207 name: negative regulation of pronephric nephron tubule development def: "Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development." [GOC:bf, GOC:TermGenie, PMID:9758706] synonym: "down regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of pronephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1900206 ! regulation of pronephric nephron tubule development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0039020 ! negatively regulates pronephric nephron tubule development relationship: RO:0002212 GO:0039020 ! negatively regulates pronephric nephron tubule development created_by: bf creation_date: 2012-03-22T09:23:23Z [Term] id: GO:1900211 name: regulation of mesenchymal cell apoptotic process involved in metanephros development def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:1904748 ! regulation of apoptotic process involved in development is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1900200 ! regulates mesenchymal cell apoptotic process involved in metanephros development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:1900200 ! regulates mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:52:50Z [Term] id: GO:1900212 name: negative regulation of mesenchymal cell apoptotic process involved in metanephros development def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "inhibition of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] synonym: "negative regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1900200 ! negatively regulates mesenchymal cell apoptotic process involved in metanephros development relationship: RO:0002212 GO:1900200 ! negatively regulates mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:53:00Z [Term] id: GO:1900213 name: positive regulation of mesenchymal cell apoptotic process involved in metanephros development def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] synonym: "positive regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] synonym: "up regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1900200 ! positively regulates mesenchymal cell apoptotic process involved in metanephros development relationship: RO:0002213 GO:1900200 ! positively regulates mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:53:09Z [Term] id: GO:1900214 name: regulation of apoptotic process involved in metanephric collecting duct development def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1900204 ! regulates apoptotic process involved in metanephric collecting duct development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:1900204 ! regulates apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:21Z [Term] id: GO:1900215 name: negative regulation of apoptotic process involved in metanephric collecting duct development def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1900204 ! negatively regulates apoptotic process involved in metanephric collecting duct development relationship: RO:0002212 GO:1900204 ! negatively regulates apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:31Z [Term] id: GO:1900216 name: positive regulation of apoptotic process involved in metanephric collecting duct development def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1900204 ! positively regulates apoptotic process involved in metanephric collecting duct development relationship: RO:0002213 GO:1900204 ! positively regulates apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:39Z [Term] id: GO:1900217 name: regulation of apoptotic process involved in metanephric nephron tubule development def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1900205 ! regulates apoptotic process involved in metanephric nephron tubule development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:1900205 ! regulates apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:53:51Z [Term] id: GO:1900218 name: negative regulation of apoptotic process involved in metanephric nephron tubule development def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1900205 ! negatively regulates apoptotic process involved in metanephric nephron tubule development relationship: RO:0002212 GO:1900205 ! negatively regulates apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:54:01Z [Term] id: GO:1900219 name: positive regulation of apoptotic process involved in metanephric nephron tubule development def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1900205 ! positively regulates apoptotic process involved in metanephric nephron tubule development relationship: RO:0002213 GO:1900205 ! positively regulates apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:54:09Z [Term] id: GO:1900247 name: regulation of cytoplasmic translational elongation def: "Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation." [GOC:TermGenie] is_a: GO:0006448 ! regulation of translational elongation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002182 ! regulates cytoplasmic translational elongation relationship: RO:0002211 GO:0002182 ! regulates cytoplasmic translational elongation created_by: vw creation_date: 2012-04-03T05:07:02Z [Term] id: GO:1900248 name: negative regulation of cytoplasmic translational elongation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation." [GOC:TermGenie] synonym: "down regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] synonym: "down-regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] synonym: "downregulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] synonym: "inhibition of cytoplasmic translational elongation" NARROW [GOC:TermGenie] is_a: GO:0045900 ! negative regulation of translational elongation is_a: GO:1900247 ! regulation of cytoplasmic translational elongation is_a: GO:2000766 ! negative regulation of cytoplasmic translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002182 ! negatively regulates cytoplasmic translational elongation relationship: RO:0002212 GO:0002182 ! negatively regulates cytoplasmic translational elongation created_by: vw creation_date: 2012-04-03T05:07:14Z [Term] id: GO:1900249 name: positive regulation of cytoplasmic translational elongation def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation." [GOC:TermGenie] synonym: "activation of cytoplasmic translational elongation" NARROW [GOC:TermGenie] synonym: "up regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] synonym: "up-regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] synonym: "upregulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] is_a: GO:0045901 ! positive regulation of translational elongation is_a: GO:1900247 ! regulation of cytoplasmic translational elongation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002182 ! positively regulates cytoplasmic translational elongation relationship: RO:0002213 GO:0002182 ! positively regulates cytoplasmic translational elongation created_by: vw creation_date: 2012-04-03T05:07:24Z [Term] id: GO:1900366 name: negative regulation of defense response to insect def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "down regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "inhibition of defense response to insect" NARROW [GOC:TermGenie] synonym: "inhibition of physiological defense response to insect" NARROW [GOC:TermGenie] synonym: "negative regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "susceptibility to insect" RELATED [] is_a: GO:0002832 ! negative regulation of response to biotic stimulus is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002213 ! negatively regulates defense response to insect relationship: RO:0002212 GO:0002213 ! negatively regulates defense response to insect property_value: RO:0002161 NCBITaxon:4895 created_by: dhl creation_date: 2012-04-12T04:44:00Z [Term] id: GO:1900367 name: positive regulation of defense response to insect def: "Any process that activates or increases the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "activation of defense response to insect" NARROW [GOC:TermGenie] synonym: "activation of physiological defense response to insect" NARROW [GOC:TermGenie] synonym: "positive regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of physiological defense response to insect" EXACT [GOC:TermGenie] is_a: GO:0002833 ! positive regulation of response to biotic stimulus is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002213 ! positively regulates defense response to insect relationship: RO:0002213 GO:0002213 ! positively regulates defense response to insect property_value: RO:0002161 NCBITaxon:4895 created_by: dhl creation_date: 2012-04-12T04:44:10Z [Term] id: GO:1900376 name: regulation of secondary metabolite biosynthetic process def: "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0043455 ! regulation of secondary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044550 ! regulates secondary metabolite biosynthetic process relationship: RO:0002211 GO:0044550 ! regulates secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:23Z [Term] id: GO:1900377 name: negative regulation of secondary metabolite biosynthetic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "inhibition of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] synonym: "negative regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044550 ! negatively regulates secondary metabolite biosynthetic process relationship: RO:0002212 GO:0044550 ! negatively regulates secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:32Z [Term] id: GO:1900378 name: positive regulation of secondary metabolite biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "activation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] synonym: "positive regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044550 ! positively regulates secondary metabolite biosynthetic process relationship: RO:0002213 GO:0044550 ! positively regulates secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:41Z [Term] id: GO:1901135 name: carbohydrate derivative metabolic process def: "The chemical reactions and pathways involving carbohydrate derivative." [GOC:TermGenie] subset: goslim_agr subset: goslim_generic subset: goslim_mouse subset: goslim_prokaryote synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:63299 ! has primary input or output carbohydrate derivative relationship: RO:0004007 CHEBI:63299 ! has primary input or output carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:09Z [Term] id: GO:1901136 name: carbohydrate derivative catabolic process def: "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative breakdown" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative catabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative degradation" EXACT [GOC:TermGenie] is_a: GO:0009056 ! catabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative relationship: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:31Z [Term] id: GO:1901137 name: carbohydrate derivative biosynthetic process def: "The chemical reactions and pathways resulting in the formation of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative anabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative biosynthesis" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative formation" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative synthesis" EXACT [GOC:TermGenie] is_a: GO:0009058 ! biosynthetic process is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:63299 ! has primary output carbohydrate derivative relationship: RO:0004008 CHEBI:63299 ! has primary output carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:39Z [Term] id: GO:1901142 name: insulin metabolic process def: "The chemical reactions and pathways involving insulin." [GOC:TermGenie] synonym: "insulin metabolism" EXACT [GOC:TermGenie] is_a: GO:0019538 ! protein metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 PR:000009054 ! has primary input or output preproinsulin relationship: RO:0004007 PR:000009054 ! has primary input or output preproinsulin property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon:4751 created_by: pm creation_date: 2012-07-13T12:32:40Z [Term] id: GO:1901143 name: insulin catabolic process def: "The chemical reactions and pathways resulting in the breakdown of insulin." [GOC:TermGenie] synonym: "insulin breakdown" EXACT [GOC:TermGenie] synonym: "insulin catabolism" EXACT [GOC:TermGenie] synonym: "insulin degradation" EXACT [GOC:TermGenie] is_a: GO:0030163 ! protein catabolic process is_a: GO:1901142 ! insulin metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 PR:000009054 ! has primary input preproinsulin relationship: RO:0004009 PR:000009054 ! has primary input preproinsulin property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon:4751 created_by: pm creation_date: 2012-07-13T12:33:03Z [Term] id: GO:1901145 name: mesenchymal cell apoptotic process involved in nephron morphogenesis def: "Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis is_a: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0072028 ! nephron morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of GO:0072028 ! nephron morphogenesis created_by: pr creation_date: 2012-07-13T01:43:51Z [Term] id: GO:1901146 name: mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis def: "Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis created_by: pr creation_date: 2012-07-13T02:40:43Z [Term] id: GO:1901147 name: mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis def: "Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: part_of GO:0072273 ! metanephric nephron morphogenesis created_by: pr creation_date: 2012-07-13T02:41:12Z [Term] id: GO:1901148 name: gene expression involved in extracellular matrix organization def: "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form." [GOC:pg, GOC:TermGenie, PMID:18668558] synonym: "expression of extracellular matrix proteins" EXACT [GOC:bf] synonym: "extracellular matrix protein production" RELATED [GOC:pg] is_a: GO:0010467 ! gene expression intersection_of: GO:0010467 ! gene expression intersection_of: part_of GO:0030198 ! extracellular matrix organization relationship: part_of GO:0030198 ! extracellular matrix organization created_by: bf creation_date: 2012-07-16T03:29:30Z [Term] id: GO:1901161 name: primary amino compound catabolic process def: "The chemical reactions and pathways resulting in the breakdown of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound breakdown" EXACT [GOC:TermGenie] synonym: "primary amino compound catabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound degradation" EXACT [GOC:TermGenie] is_a: GO:0009056 ! catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:50994 ! has primary input primary amino compound relationship: RO:0004009 CHEBI:50994 ! has primary input primary amino compound created_by: bf creation_date: 2012-07-18T04:45:06Z [Term] id: GO:1901162 name: primary amino compound biosynthetic process def: "The chemical reactions and pathways resulting in the formation of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound anabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound biosynthesis" EXACT [GOC:TermGenie] synonym: "primary amino compound formation" EXACT [GOC:TermGenie] synonym: "primary amino compound synthesis" EXACT [GOC:TermGenie] is_a: GO:0009058 ! biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:50994 ! has primary output primary amino compound relationship: RO:0004008 CHEBI:50994 ! has primary output primary amino compound created_by: bf creation_date: 2012-07-18T04:45:14Z [Term] id: GO:1901163 name: regulation of trophoblast cell migration def: "Any process that modulates the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061450 ! regulates trophoblast cell migration relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: RO:0002211 GO:0061450 ! regulates trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:06Z [Term] id: GO:1901164 name: negative regulation of trophoblast cell migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of trophoblast cell migration" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061450 ! negatively regulates trophoblast cell migration relationship: RO:0002212 GO:0061450 ! negatively regulates trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:28Z [Term] id: GO:1901165 name: positive regulation of trophoblast cell migration def: "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "activation of trophoblast cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of trophoblast cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061450 ! positively regulates trophoblast cell migration relationship: RO:0002213 GO:0061450 ! positively regulates trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:35Z [Term] id: GO:1901166 name: neural crest cell migration involved in autonomic nervous system development def: "Any neural crest cell migration that is involved in autonomic nervous system development." [GOC:BHF, GOC:TermGenie] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0048483 ! autonomic nervous system development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048483 ! autonomic nervous system development created_by: vk creation_date: 2012-07-19T08:39:56Z [Term] id: GO:1901190 name: regulation of formation of translation initiation ternary complex def: "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001677 ! regulates formation of translation initiation ternary complex relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0001677 ! regulates formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:26:58Z [Term] id: GO:1901191 name: negative regulation of formation of translation initiation ternary complex def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "down regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "downregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "downregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "inhibition of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] synonym: "inhibition of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "negative regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0045947 ! negative regulation of translational initiation is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001677 ! negatively regulates formation of translation initiation ternary complex relationship: RO:0002212 GO:0001677 ! negatively regulates formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:27:21Z [Term] id: GO:1901192 name: positive regulation of formation of translation initiation ternary complex def: "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "activation of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] synonym: "activation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "positive regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "upregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "upregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001677 ! positively regulates formation of translation initiation ternary complex relationship: RO:0002213 GO:0001677 ! positively regulates formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:27:29Z [Term] id: GO:1901201 name: regulation of extracellular matrix assembly def: "Any process that modulates the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0085029 ! regulates extracellular matrix assembly relationship: RO:0002211 GO:0085029 ! regulates extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:00Z [Term] id: GO:1901202 name: negative regulation of extracellular matrix assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "inhibition of extracellular matrix assembly" NARROW [GOC:TermGenie] is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0085029 ! negatively regulates extracellular matrix assembly relationship: RO:0002212 GO:0085029 ! negatively regulates extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:24Z [Term] id: GO:1901203 name: positive regulation of extracellular matrix assembly def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "activation of extracellular matrix assembly" NARROW [GOC:TermGenie] synonym: "up regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0085029 ! positively regulates extracellular matrix assembly relationship: RO:0002213 GO:0085029 ! positively regulates extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:32Z [Term] id: GO:1901210 name: regulation of cardiac chamber formation def: "Any process that modulates the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003207 ! regulates cardiac chamber formation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003207 ! regulates cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:18:35Z [Term] id: GO:1901211 name: negative regulation of cardiac chamber formation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac chamber formation" NARROW [GOC:TermGenie] synonym: "inhibition of heart chamber formation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003207 ! negatively regulates cardiac chamber formation relationship: RO:0002212 GO:0003207 ! negatively regulates cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:18:57Z [Term] id: GO:1901212 name: positive regulation of cardiac chamber formation def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "activation of cardiac chamber formation" NARROW [GOC:TermGenie] synonym: "activation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:1901210 ! regulation of cardiac chamber formation is_a: GO:1901221 ! positive regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003207 ! positively regulates cardiac chamber formation relationship: RO:0002213 GO:0003207 ! positively regulates cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:19:05Z [Term] id: GO:1901219 name: regulation of cardiac chamber morphogenesis def: "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:2000826 ! regulation of heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003206 ! regulates cardiac chamber morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003206 ! regulates cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:11Z [Term] id: GO:1901220 name: negative regulation of cardiac chamber morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of heart chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003206 ! negatively regulates cardiac chamber morphogenesis relationship: RO:0002212 GO:0003206 ! negatively regulates cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:34Z [Term] id: GO:1901221 name: positive regulation of cardiac chamber morphogenesis def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "activation of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of heart chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003206 ! positively regulates cardiac chamber morphogenesis relationship: RO:0002213 GO:0003206 ! positively regulates cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:42Z [Term] id: GO:1901264 name: carbohydrate derivative transport def: "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:jl, GOC:TermGenie] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative relationship: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative created_by: bf creation_date: 2012-08-16T14:51:22Z [Term] id: GO:1901317 name: regulation of flagellated sperm motility def: "Any process that modulates the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] synonym: "regulation of sperm motility" BROAD [] synonym: "regulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0060295 ! regulation of cilium movement involved in cell motility is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030317 ! regulates flagellated sperm motility relationship: RO:0002211 GO:0030317 ! regulates flagellated sperm motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:451864 property_value: RO:0002161 NCBITaxon:5782 created_by: hjd creation_date: 2012-08-22T20:50:14Z [Term] id: GO:1901318 name: negative regulation of flagellated sperm motility def: "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] synonym: "down regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "down regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "down-regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "down-regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "downregulation of sperm motility" BROAD [GOC:TermGenie] synonym: "downregulation of sperm movement" BROAD [GOC:TermGenie] synonym: "inhibition of sperm motility" NARROW [GOC:TermGenie] synonym: "inhibition of sperm movement" BROAD [GOC:TermGenie] synonym: "negative regulation of sperm motility" BROAD [] synonym: "negative regulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0003354 ! negative regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:1902020 ! negative regulation of cilium-dependent cell motility is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030317 ! negatively regulates flagellated sperm motility relationship: RO:0002212 GO:0030317 ! negatively regulates flagellated sperm motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:451864 property_value: RO:0002161 NCBITaxon:5782 created_by: hjd creation_date: 2012-08-22T20:50:35Z [Term] id: GO:1901329 name: regulation of odontoblast differentiation def: "Any process that modulates the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071895 ! regulates odontoblast differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0071895 ! regulates odontoblast differentiation created_by: hjd creation_date: 2012-08-31T16:50:05Z [Term] id: GO:1901330 name: negative regulation of odontoblast differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] synonym: "down regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of odontoblast differentiation" NARROW [GOC:TermGenie] is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation is_a: GO:1901329 ! regulation of odontoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071895 ! negatively regulates odontoblast differentiation relationship: RO:0002212 GO:0071895 ! negatively regulates odontoblast differentiation created_by: hjd creation_date: 2012-08-31T16:50:27Z [Term] id: GO:1901331 name: positive regulation of odontoblast differentiation def: "Any process that activates or increases the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] synonym: "activation of odontoblast differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of odontoblast differentiation" EXACT [GOC:TermGenie] is_a: GO:1901329 ! regulation of odontoblast differentiation is_a: GO:1902913 ! positive regulation of neuroepithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071895 ! positively regulates odontoblast differentiation relationship: RO:0002213 GO:0071895 ! positively regulates odontoblast differentiation created_by: hjd creation_date: 2012-08-31T16:50:35Z [Term] id: GO:1901342 name: regulation of vasculature development def: "Any process that modulates the frequency, rate or extent of vasculature development." [GOC:TermGenie] synonym: "regulation of vascular system development" RELATED [GOC:TermGenie] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001944 ! regulates vasculature development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0001944 ! regulates vasculature development created_by: bf creation_date: 2012-09-06T09:16:15Z [Term] id: GO:1901343 name: negative regulation of vasculature development def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development." [GOC:TermGenie] synonym: "down regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "down regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "down-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "downregulation of vascular system development" RELATED [GOC:TermGenie] synonym: "downregulation of vasculature development" EXACT [GOC:TermGenie] synonym: "inhibition of vascular system development" RELATED [GOC:TermGenie] synonym: "inhibition of vasculature development" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular system development" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001944 ! negatively regulates vasculature development relationship: RO:0002212 GO:0001944 ! negatively regulates vasculature development created_by: bf creation_date: 2012-09-06T09:17:24Z [Term] id: GO:1901374 name: acetate ester transport def: "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: RO:0004009 CHEBI:47622 ! has primary input acetate ester relationship: RO:0004009 CHEBI:47622 ! has primary input acetate ester created_by: bf creation_date: 2012-09-28T10:42:13Z [Term] id: GO:1901375 name: acetate ester transmembrane transporter activity def: "Enables the transfer of an acetate ester from one side of a membrane to the other." [GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:47622 ! has primary input acetate ester relationship: part_of GO:1901374 ! acetate ester transport relationship: RO:0004009 CHEBI:47622 ! has primary input acetate ester created_by: bf creation_date: 2012-09-28T10:47:08Z [Term] id: GO:1901382 name: regulation of chorionic trophoblast cell proliferation def: "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097360 ! regulates chorionic trophoblast cell proliferation relationship: RO:0002211 GO:0097360 ! regulates chorionic trophoblast cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: vk creation_date: 2012-10-01T10:03:13Z [Term] id: GO:1901383 name: negative regulation of chorionic trophoblast cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097360 ! negatively regulates chorionic trophoblast cell proliferation relationship: RO:0002212 GO:0097360 ! negatively regulates chorionic trophoblast cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: vk creation_date: 2012-10-01T10:04:23Z [Term] id: GO:1901384 name: positive regulation of chorionic trophoblast cell proliferation def: "Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "activation of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097360 ! positively regulates chorionic trophoblast cell proliferation relationship: RO:0002213 GO:0097360 ! positively regulates chorionic trophoblast cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: vk creation_date: 2012-10-01T10:04:41Z [Term] id: GO:1901401 name: regulation of tetrapyrrole metabolic process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033013 ! regulates tetrapyrrole metabolic process relationship: RO:0002211 GO:0033013 ! regulates tetrapyrrole metabolic process created_by: tt creation_date: 2012-10-01T14:34:03Z [Term] id: GO:1901404 name: regulation of tetrapyrrole catabolic process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033015 ! regulates tetrapyrrole catabolic process relationship: RO:0002211 GO:0033015 ! regulates tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:38:12Z [Term] id: GO:1901405 name: negative regulation of tetrapyrrole catabolic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033015 ! negatively regulates tetrapyrrole catabolic process relationship: RO:0002212 GO:0033015 ! negatively regulates tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:39:22Z [Term] id: GO:1901406 name: positive regulation of tetrapyrrole catabolic process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033015 ! positively regulates tetrapyrrole catabolic process relationship: RO:0002213 GO:0033015 ! positively regulates tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:39:40Z [Term] id: GO:1901457 name: regulation of response to acetate def: "Any process that modulates the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010034 ! regulates response to acetate relationship: RO:0002211 GO:0010034 ! regulates response to acetate created_by: tt creation_date: 2012-10-02T14:25:06Z [Term] id: GO:1901458 name: negative regulation of response to acetate def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "down-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "downregulation of response to acetate" EXACT [GOC:TermGenie] synonym: "inhibition of response to acetate" NARROW [GOC:TermGenie] is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010034 ! negatively regulates response to acetate relationship: RO:0002212 GO:0010034 ! negatively regulates response to acetate created_by: tt creation_date: 2012-10-02T14:26:15Z [Term] id: GO:1901459 name: positive regulation of response to acetate def: "Any process that activates or increases the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of response to acetate" NARROW [GOC:TermGenie] synonym: "up regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "up-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "upregulation of response to acetate" EXACT [GOC:TermGenie] is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010034 ! positively regulates response to acetate relationship: RO:0002213 GO:0010034 ! positively regulates response to acetate created_by: tt creation_date: 2012-10-02T14:26:34Z [Term] id: GO:1901463 name: regulation of tetrapyrrole biosynthetic process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033014 ! regulates tetrapyrrole biosynthetic process relationship: RO:0002211 GO:0033014 ! regulates tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:34:14Z [Term] id: GO:1901464 name: negative regulation of tetrapyrrole biosynthetic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033014 ! negatively regulates tetrapyrrole biosynthetic process relationship: RO:0002212 GO:0033014 ! negatively regulates tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:35:26Z [Term] id: GO:1901465 name: positive regulation of tetrapyrrole biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033014 ! positively regulates tetrapyrrole biosynthetic process relationship: RO:0002213 GO:0033014 ! positively regulates tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:35:43Z [Term] id: GO:1901505 name: carbohydrate derivative transmembrane transporter activity def: "Enables the transfer of carbohydrate derivative from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] synonym: "carbohydrate derivative transporter activity" RELATED [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative relationship: part_of GO:1901264 {source="GO_REF:0000090"} ! carbohydrate derivative transport relationship: RO:0004009 CHEBI:63299 ! has primary input carbohydrate derivative created_by: pr creation_date: 2012-10-17T10:31:22Z [Term] id: GO:1901509 name: regulation of endothelial tube morphogenesis def: "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis." [GOC:dph, GOC:TermGenie] is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061154 ! regulates endothelial tube morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0061154 ! regulates endothelial tube morphogenesis created_by: dph creation_date: 2012-10-17T14:30:40Z [Term] id: GO:1901532 name: regulation of hematopoietic progenitor cell differentiation def: "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002244 ! regulates hematopoietic progenitor cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0002244 ! regulates hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:01Z [Term] id: GO:1901533 name: negative regulation of hematopoietic progenitor cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "down regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "down regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "down-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "downregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "inhibition of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002244 ! negatively regulates hematopoietic progenitor cell differentiation relationship: RO:0002212 GO:0002244 ! negatively regulates hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:06Z [Term] id: GO:1901534 name: positive regulation of hematopoietic progenitor cell differentiation def: "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "activation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "activation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "activation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "activation of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic progenitor cell differentiation" EXACT [] synonym: "up regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "up regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "up-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "upregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002244 ! positively regulates hematopoietic progenitor cell differentiation relationship: RO:0002213 GO:0002244 ! positively regulates hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:14Z [Term] id: GO:1901550 name: regulation of endothelial cell development def: "Any process that modulates the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] is_a: GO:0045601 ! regulation of endothelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001885 ! regulates endothelial cell development relationship: RO:0002211 GO:0001885 ! regulates endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:50Z [Term] id: GO:1901551 name: negative regulation of endothelial cell development def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "down regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial cell development" NARROW [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001885 ! negatively regulates endothelial cell development relationship: RO:0002212 GO:0001885 ! negatively regulates endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:54Z [Term] id: GO:1901552 name: positive regulation of endothelial cell development def: "Any process that activates or increases the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "activation of endothelial cell development" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001885 ! positively regulates endothelial cell development relationship: RO:0002213 GO:0001885 ! positively regulates endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:58Z [Term] id: GO:1901589 name: axon microtubule bundle def: "An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment." [GOC:TermGenie, NIF_Subcellular:sao707332678] synonym: "axon microtubule fascicle" EXACT [] synonym: "microtubule bundle of axon" EXACT [GOC:TermGenie] synonym: "microtubule fascicle of axon" EXACT [GOC:TermGenie] xref: NIF_Subcellular:sao707332678 is_a: GO:0097427 ! microtubule bundle intersection_of: GO:0097427 ! microtubule bundle intersection_of: part_of GO:0030424 ! axon relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of GO:0030424 ! axon created_by: pr creation_date: 2012-11-07T15:37:12Z [Term] id: GO:1901605 name: alpha-amino acid metabolic process def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0006520 ! amino acid metabolic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: RO:0004007 CHEBI:78608 ! has primary input or output alpha-amino-acid zwitterion relationship: RO:0004007 CHEBI:78608 ! has primary input or output alpha-amino-acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:50Z [Term] id: GO:1901606 name: alpha-amino acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie] synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie] is_a: GO:0009063 ! amino acid catabolic process is_a: GO:0046395 ! carboxylic acid catabolic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: RO:0004009 CHEBI:78608 ! has primary input alpha-amino-acid zwitterion relationship: RO:0004009 CHEBI:78608 ! has primary input alpha-amino-acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:54Z [Term] id: GO:1901607 name: alpha-amino acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid anabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie] synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie] synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] is_a: GO:0008652 ! amino acid biosynthetic process is_a: GO:0046394 ! carboxylic acid biosynthetic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: RO:0004008 CHEBI:78608 ! has primary output alpha-amino-acid zwitterion relationship: RO:0004008 CHEBI:78608 ! has primary output alpha-amino-acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:58Z [Term] id: GO:1901608 name: regulation of vesicle transport along microtubule def: "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0047496 ! regulates vesicle transport along microtubule relationship: RO:0002211 GO:0047496 ! regulates vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:44Z [Term] id: GO:1901609 name: negative regulation of vesicle transport along microtubule def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "down regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "downregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "inhibition of vesicle transport along microtubule" NARROW [GOC:TermGenie] synonym: "negative regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0047496 ! negatively regulates vesicle transport along microtubule relationship: RO:0002212 GO:0047496 ! negatively regulates vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:48Z [Term] id: GO:1901610 name: positive regulation of vesicle transport along microtubule def: "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "activation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "activation of vesicle transport along microtubule" NARROW [GOC:TermGenie] synonym: "positive regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "upregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0047496 ! positively regulates vesicle transport along microtubule relationship: RO:0002213 GO:0047496 ! positively regulates vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:53Z [Term] id: GO:1901652 name: response to peptide def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion relationship: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion created_by: pr creation_date: 2012-11-20T09:45:15Z [Term] id: GO:1901653 name: cellular response to peptide def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1901652 ! response to peptide intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion created_by: pr creation_date: 2012-11-20T09:45:19Z [Term] id: GO:1901654 name: response to ketone alt_id: GO:1990369 def: "A response that results in a state of tolerance to ketone." [GOC:mengo_curators, PMID:23356676] synonym: "process resulting in tolerance to ketone" NARROW [] is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:17087 ! has primary input ketone relationship: RO:0004009 CHEBI:17087 ! has primary input ketone created_by: pr creation_date: 2012-11-20T10:55:47Z [Term] id: GO:1901655 name: cellular response to ketone def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus." [GOC:pr, GOC:TermGenie] is_a: GO:1901654 ! response to ketone is_a: GO:1901701 ! cellular response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:17087 ! has primary input ketone created_by: pr creation_date: 2012-11-20T10:55:51Z [Term] id: GO:1901682 name: sulfur compound transmembrane transporter activity def: "Enables the transfer of a sulfur compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] synonym: "sulfur molecular entity transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity relationship: RO:0004009 CHEBI:26835 ! has primary input sulfur molecular entity created_by: pr creation_date: 2012-11-26T20:45:29Z [Term] id: GO:1901692 name: regulation of compound eye retinal cell apoptotic process def: "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990010 ! regulates compound eye retinal cell apoptotic process relationship: RO:0002211 GO:1990010 ! regulates compound eye retinal cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-12-12T10:28:35Z [Term] id: GO:1901693 name: negative regulation of compound eye retinal cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "down regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990010 ! negatively regulates compound eye retinal cell apoptotic process relationship: RO:0002212 GO:1990010 ! negatively regulates compound eye retinal cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-12-12T10:28:40Z [Term] id: GO:1901694 name: positive regulation of compound eye retinal cell apoptotic process alt_id: GO:0046675 def: "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "activation of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] synonym: "induction of compound eye retinal cell programmed cell death" RELATED [] synonym: "up regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0046672 ! positive regulation of compound eye retinal cell programmed cell death is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990010 ! positively regulates compound eye retinal cell apoptotic process relationship: RO:0002213 GO:1990010 ! positively regulates compound eye retinal cell apoptotic process created_by: pr creation_date: 2012-12-12T10:28:45Z [Term] id: GO:1901698 name: response to nitrogen compound def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "response to nitrogen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity relationship: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27194" xsd:anyURI created_by: pr creation_date: 2012-12-13T15:06:08Z [Term] id: GO:1901699 name: cellular response to nitrogen compound def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "cellular response to nitrogen molecular entity" EXACT [] is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:51143 ! has primary input nitrogen molecular entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27194" xsd:anyURI created_by: pr creation_date: 2012-12-13T15:06:13Z [Term] id: GO:1901700 name: response to oxygen-containing compound def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_annotate synonym: "response to oxygen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:25806 ! has primary input oxygen molecular entity relationship: RO:0004009 CHEBI:25806 ! has primary input oxygen molecular entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/27194" xsd:anyURI created_by: pr creation_date: 2012-12-13T15:11:37Z [Term] id: GO:1901701 name: cellular response to oxygen-containing compound def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "cellular response to oxygen molecular entity" EXACT [] is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:25806 ! has primary input oxygen molecular entity created_by: pr creation_date: 2012-12-13T15:11:42Z [Term] id: GO:1901702 name: salt transmembrane transporter activity def: "Enables the transfer of salt from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: RO:0004009 CHEBI:24866 ! has primary input salt relationship: RO:0004009 CHEBI:24866 ! has primary input salt created_by: pr creation_date: 2012-12-13T15:14:47Z [Term] id: GO:1901706 name: mesenchymal cell differentiation involved in bone development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state." [GOC:hjd, GOC:TermGenie, PMID:21571217] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0060348 ! bone development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060348 ! bone development created_by: hjd creation_date: 2012-12-14T16:04:16Z [Term] id: GO:1901722 name: regulation of cell proliferation involved in kidney development def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072111 ! regulates cell proliferation involved in kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0072111 ! regulates cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:31Z [Term] id: GO:1901723 name: negative regulation of cell proliferation involved in kidney development def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "down regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "inhibition of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072111 ! negatively regulates cell proliferation involved in kidney development relationship: RO:0002212 GO:0072111 ! negatively regulates cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:35Z [Term] id: GO:1901724 name: positive regulation of cell proliferation involved in kidney development def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "activation of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] synonym: "up regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072111 ! positively regulates cell proliferation involved in kidney development relationship: RO:0002213 GO:0072111 ! positively regulates cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:40Z [Term] id: GO:1901861 name: regulation of muscle tissue development def: "Any process that modulates the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060537 ! regulates muscle tissue development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0060537 ! regulates muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:47Z [Term] id: GO:1901862 name: negative regulation of muscle tissue development def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "down regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of muscle tissue development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060537 ! negatively regulates muscle tissue development relationship: RO:0002212 GO:0060537 ! negatively regulates muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:52Z [Term] id: GO:1901863 name: positive regulation of muscle tissue development def: "Any process that activates or increases the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "activation of muscle tissue development" NARROW [GOC:TermGenie] synonym: "up regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060537 ! positively regulates muscle tissue development relationship: RO:0002213 GO:0060537 ! positively regulates muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:57Z [Term] id: GO:1901879 name: regulation of protein depolymerization def: "Any process that modulates the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051261 ! regulates protein depolymerization relationship: RO:0002211 GO:0051261 ! regulates protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:23Z [Term] id: GO:1901880 name: negative regulation of protein depolymerization def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "down regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "inhibition of protein depolymerization" NARROW [GOC:TermGenie] synonym: "inhibition of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051261 ! negatively regulates protein depolymerization relationship: RO:0002212 GO:0051261 ! negatively regulates protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:28Z [Term] id: GO:1901881 name: positive regulation of protein depolymerization def: "Any process that activates or increases the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "activation of protein depolymerization" NARROW [GOC:TermGenie] synonym: "activation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "activation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051261 ! positively regulates protein depolymerization relationship: RO:0002213 GO:0051261 ! positively regulates protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:32Z [Term] id: GO:1901888 name: regulation of cell junction assembly def: "Any process that modulates the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0034329 ! regulates cell junction assembly relationship: RO:0002211 GO:0034329 ! regulates cell junction assembly property_value: RO:0002161 NCBITaxon:4751 created_by: tb creation_date: 2013-02-06T19:40:32Z [Term] id: GO:1901889 name: negative regulation of cell junction assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "down regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "inhibition of cell junction assembly" NARROW [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0034329 ! negatively regulates cell junction assembly relationship: RO:0002212 GO:0034329 ! negatively regulates cell junction assembly property_value: RO:0002161 NCBITaxon:4751 created_by: tb creation_date: 2013-02-06T19:40:41Z [Term] id: GO:1901890 name: positive regulation of cell junction assembly def: "Any process that activates or increases the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "activation of cell junction assembly" NARROW [GOC:TermGenie] synonym: "up regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell junction assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0034329 ! positively regulates cell junction assembly relationship: RO:0002213 GO:0034329 ! positively regulates cell junction assembly property_value: RO:0002161 NCBITaxon:4751 created_by: tb creation_date: 2013-02-06T19:40:46Z [Term] id: GO:1901950 name: dense core granule transport def: "The directed movement a dense core granule within a cell." [GOC:kmv, GOC:TermGenie, PMID:23358451] comment: goslim_synapse synonym: "dense core vesicle transport" EXACT [GOC:TermGenie] is_a: GO:0016482 ! cytosolic transport is_a: GO:0032253 ! dense core granule localization is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:0005829 ! occurs in cytosol intersection_of: RO:0004009 GO:0031045 ! has primary input dense core granule created_by: pr creation_date: 2013-02-19T13:00:52Z [Term] id: GO:1901951 name: regulation of anterograde dense core granule transport def: "Any process that modulates the frequency, rate or extent of anterograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] is_a: GO:1901608 ! regulation of vesicle transport along microtubule is_a: GO:1904809 ! regulation of dense core granule transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990048 ! regulates anterograde neuronal dense core vesicle transport relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:1990048 ! regulates anterograde neuronal dense core vesicle transport created_by: pr creation_date: 2013-02-19T13:36:21Z [Term] id: GO:1901952 name: negative regulation of anterograde dense core granule transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] synonym: "down regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "down-regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "downregulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "inhibition of anterograde dense core granule transport" NARROW [GOC:TermGenie] is_a: GO:1901609 ! negative regulation of vesicle transport along microtubule is_a: GO:1901951 ! regulation of anterograde dense core granule transport is_a: GO:1904810 ! negative regulation of dense core granule transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990048 ! negatively regulates anterograde neuronal dense core vesicle transport relationship: RO:0002212 GO:1990048 ! negatively regulates anterograde neuronal dense core vesicle transport created_by: pr creation_date: 2013-02-19T13:36:30Z [Term] id: GO:1901953 name: positive regulation of anterograde dense core granule transport def: "Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] synonym: "activation of anterograde dense core granule transport" NARROW [GOC:TermGenie] synonym: "up regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "up-regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "upregulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] is_a: GO:1901610 ! positive regulation of vesicle transport along microtubule is_a: GO:1901951 ! regulation of anterograde dense core granule transport is_a: GO:1904811 ! positive regulation of dense core granule transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990048 ! positively regulates anterograde neuronal dense core vesicle transport relationship: RO:0002213 GO:1990048 ! positively regulates anterograde neuronal dense core vesicle transport created_by: pr creation_date: 2013-02-19T13:36:35Z [Term] id: GO:1901954 name: regulation of retrograde dense core granule transport def: "Any process that modulates the frequency, rate or extent of retrograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] is_a: GO:1901608 ! regulation of vesicle transport along microtubule is_a: GO:1904809 ! regulation of dense core granule transport is_a: GO:2001017 ! regulation of retrograde axon cargo transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990049 ! regulates retrograde neuronal dense core vesicle transport relationship: RO:0002211 GO:1990049 ! regulates retrograde neuronal dense core vesicle transport created_by: pr creation_date: 2013-02-19T13:36:43Z [Term] id: GO:1901955 name: negative regulation of retrograde dense core granule transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] synonym: "down regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "down-regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "downregulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "inhibition of retrograde dense core granule transport" NARROW [GOC:TermGenie] is_a: GO:1901609 ! negative regulation of vesicle transport along microtubule is_a: GO:1901954 ! regulation of retrograde dense core granule transport is_a: GO:1904810 ! negative regulation of dense core granule transport is_a: GO:2001018 ! negative regulation of retrograde axon cargo transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990049 ! negatively regulates retrograde neuronal dense core vesicle transport relationship: RO:0002212 GO:1990049 ! negatively regulates retrograde neuronal dense core vesicle transport created_by: pr creation_date: 2013-02-19T13:36:47Z [Term] id: GO:1901956 name: positive regulation of retrograde dense core granule transport def: "Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] synonym: "activation of retrograde dense core granule transport" NARROW [GOC:TermGenie] synonym: "up regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "up-regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] synonym: "upregulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] is_a: GO:1901610 ! positive regulation of vesicle transport along microtubule is_a: GO:1901954 ! regulation of retrograde dense core granule transport is_a: GO:1904811 ! positive regulation of dense core granule transport is_a: GO:2001019 ! positive regulation of retrograde axon cargo transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990049 ! positively regulates retrograde neuronal dense core vesicle transport relationship: RO:0002213 GO:1990049 ! positively regulates retrograde neuronal dense core vesicle transport created_by: pr creation_date: 2013-02-19T13:36:52Z [Term] id: GO:1901963 name: regulation of cell proliferation involved in outflow tract morphogenesis def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061325 ! regulates cell proliferation involved in outflow tract morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0061325 ! regulates cell proliferation involved in outflow tract morphogenesis created_by: dph creation_date: 2013-02-20T20:30:26Z [Term] id: GO:1901964 name: positive regulation of cell proliferation involved in outflow tract morphogenesis def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] synonym: "activation of cell proliferation involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061325 ! positively regulates cell proliferation involved in outflow tract morphogenesis relationship: RO:0002213 GO:0061325 ! positively regulates cell proliferation involved in outflow tract morphogenesis created_by: dph creation_date: 2013-02-20T20:30:31Z [Term] id: GO:1902017 name: regulation of cilium assembly def: "Any process that modulates the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "regulation of cilium biogenesis" RELATED [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060271 ! regulates cilium assembly relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0060271 ! regulates cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2013-03-26T18:10:51Z [Term] id: GO:1902018 name: negative regulation of cilium assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "down regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of ciliogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cilium assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of cilium biogenesis" RELATED [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902116 ! negative regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060271 ! negatively regulates cilium assembly relationship: RO:0002212 GO:0060271 ! negatively regulates cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2013-03-26T18:10:56Z [Term] id: GO:1902019 name: regulation of cilium-dependent cell motility def: "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "regulation of ciliary cell motility" RELATED [] synonym: "regulation of cilium cell motility" EXACT [] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060285 ! regulates cilium-dependent cell motility relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0060285 ! regulates cilium-dependent cell motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:451864 property_value: RO:0002161 NCBITaxon:5782 created_by: jl creation_date: 2013-03-27T14:42:38Z [Term] id: GO:1902020 name: negative regulation of cilium-dependent cell motility def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "down regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "down-regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "downregulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "inhibition of ciliary cell motility" NARROW [GOC:TermGenie] synonym: "negative regulation of ciliary cell motility" RELATED [] synonym: "negative regulation of cilium cell motility" EXACT [] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060285 ! negatively regulates cilium-dependent cell motility relationship: RO:0002212 GO:0060285 ! negatively regulates cilium-dependent cell motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:451864 property_value: RO:0002161 NCBITaxon:5782 created_by: jl creation_date: 2013-03-27T14:42:42Z [Term] id: GO:1902033 name: regulation of hematopoietic stem cell proliferation def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071425 ! regulates hematopoietic stem cell proliferation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0071425 ! regulates hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:19Z [Term] id: GO:1902034 name: negative regulation of hematopoietic stem cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:1903707 ! negative regulation of hemopoiesis is_a: GO:2000647 ! negative regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071425 ! negatively regulates hematopoietic stem cell proliferation relationship: RO:0002212 GO:0071425 ! negatively regulates hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:24Z [Term] id: GO:1902035 name: positive regulation of hematopoietic stem cell proliferation def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "activation of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:2000648 ! positive regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071425 ! positively regulates hematopoietic stem cell proliferation relationship: RO:0002213 GO:0071425 ! positively regulates hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:31Z [Term] id: GO:1902036 name: regulation of hematopoietic stem cell differentiation def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] xref: Reactome:R-HSA-8939236 "RUNX1 regulates transcription of genes involved in differentiation of HSCs" is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060218 ! regulates hematopoietic stem cell differentiation relationship: RO:0002211 GO:0060218 ! regulates hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:09Z [Term] id: GO:1902037 name: negative regulation of hematopoietic stem cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060218 ! negatively regulates hematopoietic stem cell differentiation relationship: RO:0002212 GO:0060218 ! negatively regulates hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:14Z [Term] id: GO:1902038 name: positive regulation of hematopoietic stem cell differentiation def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "activation of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060218 ! positively regulates hematopoietic stem cell differentiation relationship: RO:0002213 GO:0060218 ! positively regulates hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:19Z [Term] id: GO:1902074 name: response to salt def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] synonym: "response to salinity" NARROW [GOC:mls] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:24866 ! has primary input salt relationship: RO:0004009 CHEBI:24866 ! has primary input salt created_by: mls creation_date: 2013-04-22T15:41:57Z [Term] id: GO:1902075 name: cellular response to salt def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] synonym: "cellular response to salinity" NARROW [GOC:mls] is_a: GO:0070887 ! cellular response to chemical stimulus is_a: GO:1902074 ! response to salt intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:24866 ! has primary input salt created_by: mls creation_date: 2013-04-22T15:42:02Z [Term] id: GO:1902093 name: positive regulation of flagellated sperm motility def: "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:jh2, GOC:krc, GOC:TermGenie, PMID:7513657] synonym: "activation of sperm motility" NARROW [GOC:TermGenie] synonym: "activation of sperm movement" BROAD [GOC:TermGenie] synonym: "positive regulation of sperm motility" BROAD [] synonym: "positive regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "up regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "up regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "up-regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "up-regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "upregulation of sperm motility" BROAD [GOC:TermGenie] synonym: "upregulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0003353 ! positive regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:2000155 ! positive regulation of cilium-dependent cell motility is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030317 ! positively regulates flagellated sperm motility relationship: RO:0002213 GO:0030317 ! positively regulates flagellated sperm motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:451864 property_value: RO:0002161 NCBITaxon:5782 created_by: bf creation_date: 2013-04-29T09:15:25Z [Term] id: GO:1902105 name: regulation of leukocyte differentiation def: "Any process that modulates the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002521 ! regulates leukocyte differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0002521 ! regulates leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:42Z [Term] id: GO:1902106 name: negative regulation of leukocyte differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "down regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of immune cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of leucocyte differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903707 ! negative regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002521 ! negatively regulates leukocyte differentiation relationship: RO:0002212 GO:0002521 ! negatively regulates leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:47Z [Term] id: GO:1902107 name: positive regulation of leukocyte differentiation def: "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "activation of immune cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of leucocyte differentiation" NARROW [GOC:TermGenie] synonym: "activation of leukocyte differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903708 ! positive regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002521 ! positively regulates leukocyte differentiation relationship: RO:0002213 GO:0002521 ! positively regulates leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:52Z [Term] id: GO:1902115 name: regulation of organelle assembly def: "Any process that modulates the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0070925 ! regulates organelle assembly relationship: RO:0002211 GO:0070925 ! regulates organelle assembly created_by: pr creation_date: 2013-05-14T09:43:21Z [Term] id: GO:1902116 name: negative regulation of organelle assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "down regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "downregulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "inhibition of organelle assembly" NARROW [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0070925 ! negatively regulates organelle assembly relationship: RO:0002212 GO:0070925 ! negatively regulates organelle assembly created_by: pr creation_date: 2013-05-14T09:43:31Z [Term] id: GO:1902117 name: positive regulation of organelle assembly def: "Any process that activates or increases the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "activation of organelle assembly" NARROW [GOC:TermGenie] synonym: "up regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "upregulation of organelle assembly" EXACT [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0070925 ! positively regulates organelle assembly relationship: RO:0002213 GO:0070925 ! positively regulates organelle assembly created_by: pr creation_date: 2013-05-14T09:43:36Z [Term] id: GO:1902217 name: erythrocyte apoptotic process def: "Any apoptotic process in an erythrocyte." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "RBC apoptosis" NARROW [GOC:TermGenie] synonym: "RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033028 ! myeloid cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000232 ! occurs in erythrocyte relationship: BFO:0000066 CL:0000232 ! occurs in erythrocyte property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-13T10:02:29Z [Term] id: GO:1902250 name: regulation of erythrocyte apoptotic process def: "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902217 ! regulates erythrocyte apoptotic process relationship: RO:0002211 GO:1902217 ! regulates erythrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-20T19:30:53Z [Term] id: GO:1902251 name: negative regulation of erythrocyte apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "down regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of erythrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of RBC apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of red blood cell apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902217 ! negatively regulates erythrocyte apoptotic process relationship: RO:0002212 GO:1902217 ! negatively regulates erythrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-20T19:30:59Z [Term] id: GO:1902252 name: positive regulation of erythrocyte apoptotic process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "activation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of erythrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "activation of RBC apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of red blood cell apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902217 ! positively regulates erythrocyte apoptotic process relationship: RO:0002213 GO:1902217 ! positively regulates erythrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-20T19:31:04Z [Term] id: GO:1902256 name: regulation of apoptotic process involved in outflow tract morphogenesis def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003275 ! regulates apoptotic process involved in outflow tract morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003275 ! regulates apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:24Z [Term] id: GO:1902257 name: negative regulation of apoptotic process involved in outflow tract morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "down regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003275 ! negatively regulates apoptotic process involved in outflow tract morphogenesis relationship: RO:0002212 GO:0003275 ! negatively regulates apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:30Z [Term] id: GO:1902258 name: positive regulation of apoptotic process involved in outflow tract morphogenesis def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "activation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003275 ! positively regulates apoptotic process involved in outflow tract morphogenesis relationship: RO:0002213 GO:0003275 ! positively regulates apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:42Z [Term] id: GO:1902262 name: apoptotic process involved in blood vessel morphogenesis def: "Any apoptotic process that is involved in blood vessel morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16163358] synonym: "apoptosis involved in patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "apoptotic cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "apoptotic program involved in patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in patterning of blood vessels" RELATED [GOC:TermGenie] synonym: "type I programmed cell death involved in patterning of blood vessels" NARROW [GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0048514 ! blood vessel morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0048514 ! blood vessel morphogenesis created_by: dph creation_date: 2013-06-25T16:16:00Z [Term] id: GO:1902275 name: regulation of chromatin organization alt_id: GO:0001672 alt_id: GO:1903308 def: "Any process that modulates the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:bf, GOC:TermGenie, GOC:vw, PMID:18314879] synonym: "regulation of chromatin assembly or disassembly" RELATED [] synonym: "regulation of chromatin assembly/disassembly" RELATED [] synonym: "regulation of chromatin modification" RELATED [] synonym: "regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006325 ! regulates chromatin organization relationship: RO:0002211 GO:0006325 ! regulates chromatin organization created_by: bf creation_date: 2013-07-01T13:21:52Z [Term] id: GO:1902305 name: regulation of sodium ion transmembrane transport def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035725 ! regulates sodium ion transmembrane transport relationship: RO:0002211 GO:0035725 ! regulates sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:33:53Z [Term] id: GO:1902306 name: negative regulation of sodium ion transmembrane transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "down regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "inhibition of sodium ion membrane transport" NARROW [GOC:TermGenie] synonym: "inhibition of sodium ion transmembrane transport" NARROW [GOC:TermGenie] synonym: "negative regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0010766 ! negative regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904063 ! negative regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035725 ! negatively regulates sodium ion transmembrane transport relationship: RO:0002212 GO:0035725 ! negatively regulates sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:34:01Z [Term] id: GO:1902307 name: positive regulation of sodium ion transmembrane transport def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "activation of sodium ion membrane transport" NARROW [GOC:TermGenie] synonym: "activation of sodium ion transmembrane transport" NARROW [GOC:TermGenie] synonym: "positive regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0010765 ! positive regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904064 ! positive regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035725 ! positively regulates sodium ion transmembrane transport relationship: RO:0002213 GO:0035725 ! positively regulates sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:34:18Z [Term] id: GO:1902337 name: regulation of apoptotic process involved in morphogenesis def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060561 ! regulates apoptotic process involved in morphogenesis relationship: RO:0002211 GO:0060561 ! regulates apoptotic process involved in morphogenesis property_value: RO:0002161 NCBITaxon:4896 created_by: sart creation_date: 2013-07-29T15:03:16Z [Term] id: GO:1902338 name: negative regulation of apoptotic process involved in morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "down regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060561 ! negatively regulates apoptotic process involved in morphogenesis relationship: RO:0002212 GO:0060561 ! negatively regulates apoptotic process involved in morphogenesis property_value: RO:0002161 NCBITaxon:4896 created_by: sart creation_date: 2013-07-29T15:03:25Z [Term] id: GO:1902339 name: positive regulation of apoptotic process involved in morphogenesis def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "activation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "activation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060561 ! positively regulates apoptotic process involved in morphogenesis relationship: RO:0002213 GO:0060561 ! positively regulates apoptotic process involved in morphogenesis property_value: RO:0002161 NCBITaxon:4896 created_by: sart creation_date: 2013-07-29T15:03:33Z [Term] id: GO:1902340 name: negative regulation of chromosome condensation def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." [GOC:TermGenie, PMID:23219725] synonym: "down regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "inhibition of chromosome condensation" NARROW [GOC:TermGenie] synonym: "inhibition of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear chromosome condensation" NARROW [GOC:TermGenie] synonym: "negative regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030261 ! negatively regulates chromosome condensation relationship: RO:0002212 GO:0030261 ! negatively regulates chromosome condensation created_by: dgf creation_date: 2013-07-29T20:54:14Z [Term] id: GO:1902358 name: sulfate transmembrane transport def: "The directed movement of sulfate across a membrane." [GOC:dph, GOC:TermGenie, PMID:9055073] synonym: "sulphate transport" EXACT [] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0055085 ! transmembrane transport is_a: GO:0072348 ! sulfur compound transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:16189 ! has primary input sulfate relationship: RO:0004009 CHEBI:16189 ! has primary input sulfate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28653" xsd:anyURI created_by: dph creation_date: 2013-08-14T14:46:04Z [Term] id: GO:1902369 name: negative regulation of RNA catabolic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:16640457] synonym: "down regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "inhibition of RNA breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of RNA catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of RNA catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of RNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA degradation" EXACT [GOC:TermGenie] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0051253 ! negative regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006401 ! negatively regulates RNA catabolic process relationship: RO:0002212 GO:0006401 ! negatively regulates RNA catabolic process created_by: bf creation_date: 2013-08-22T14:59:39Z [Term] id: GO:1902370 name: regulation of tRNA catabolic process def: "Any process that modulates the frequency, rate or extent of tRNA catabolic process." [GOC:bf, GOC:TermGenie] synonym: "regulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "regulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "regulation of tRNA degradation" EXACT [GOC:TermGenie] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:1903326 ! regulation of tRNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0016078 ! regulates tRNA decay relationship: RO:0002211 GO:0016078 ! regulates tRNA decay created_by: bf creation_date: 2013-08-22T15:08:12Z [Term] id: GO:1902371 name: negative regulation of tRNA catabolic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:22919049] synonym: "down regulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of tRNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tRNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of tRNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tRNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of tRNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tRNA degradation" EXACT [GOC:TermGenie] synonym: "inhibition of tRNA breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of tRNA catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of tRNA catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of tRNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tRNA degradation" EXACT [GOC:TermGenie] is_a: GO:1902369 ! negative regulation of RNA catabolic process is_a: GO:1902370 ! regulation of tRNA catabolic process is_a: GO:1903327 ! negative regulation of tRNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0016078 ! negatively regulates tRNA decay relationship: RO:0002212 GO:0016078 ! negatively regulates tRNA decay created_by: bf creation_date: 2013-08-22T15:08:20Z [Term] id: GO:1902372 name: positive regulation of tRNA catabolic process def: "Any process that activates or increases the frequency, rate or extent of tRNA catabolic process." [GOC:bf, GOC:TermGenie] synonym: "activation of tRNA breakdown" NARROW [GOC:TermGenie] synonym: "activation of tRNA catabolic process" NARROW [GOC:TermGenie] synonym: "activation of tRNA catabolism" NARROW [GOC:TermGenie] synonym: "activation of tRNA degradation" NARROW [GOC:TermGenie] synonym: "positive regulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tRNA degradation" EXACT [GOC:TermGenie] synonym: "up regulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of tRNA catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tRNA degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of tRNA catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tRNA degradation" EXACT [GOC:TermGenie] synonym: "upregulation of tRNA breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of tRNA catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tRNA catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tRNA degradation" EXACT [GOC:TermGenie] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:1902370 ! regulation of tRNA catabolic process is_a: GO:1903328 ! positive regulation of tRNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0016078 ! positively regulates tRNA decay relationship: RO:0002213 GO:0016078 ! positively regulates tRNA decay created_by: bf creation_date: 2013-08-22T15:08:29Z [Term] id: GO:1902414 name: protein localization to cell junction def: "A process in which a protein is transported to, or maintained in, a location within a cell junction." [GOC:TermGenie, PMID:18332111] synonym: "protein localisation in cell junction" EXACT [GOC:TermGenie] synonym: "protein localisation to cell junction" EXACT [GOC:TermGenie] synonym: "protein localization in cell junction" EXACT [GOC:TermGenie] is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0030054 ! has target end location cell junction relationship: RO:0002339 GO:0030054 ! has target end location cell junction created_by: tb creation_date: 2013-09-13T16:55:57Z [Term] id: GO:1902434 name: sulfate import across plasma membrane def: "The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:TermGenie, PMID:14723223] synonym: "sulfate import into cell" EXACT [] synonym: "sulphate import into cell" EXACT [] is_a: GO:0098658 ! inorganic anion import across plasma membrane is_a: GO:1902358 ! sulfate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: RO:0002338 GO:0005576 ! has target start location extracellular region intersection_of: RO:0002339 GO:0005829 ! has target end location cytosol intersection_of: RO:0002342 GO:0005886 ! results in transport across plasma membrane intersection_of: RO:0004009 CHEBI:16189 ! has primary input sulfate created_by: mah creation_date: 2013-10-07T14:12:38Z [Term] id: GO:1902455 name: negative regulation of stem cell population maintenance def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "down regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "downregulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "inhibition of stem cell maintenance" NARROW [GOC:TermGenie] synonym: "negative regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019827 ! negatively regulates stem cell population maintenance relationship: RO:0002212 GO:0019827 ! negatively regulates stem cell population maintenance property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: cjm creation_date: 2013-10-16T22:19:17Z [Term] id: GO:1902459 name: positive regulation of stem cell population maintenance def: "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "activation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "activation of stem cell maintenance" NARROW [GOC:TermGenie] synonym: "positive regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "upregulation of stem cell maintenance" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019827 ! positively regulates stem cell population maintenance relationship: RO:0002213 GO:0019827 ! positively regulates stem cell population maintenance property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: cjm creation_date: 2013-10-16T22:27:47Z [Term] id: GO:1902463 name: protein localization to cell leading edge def: "A process in which a protein is transported to, or maintained in, a location within a cell leading edge." [GOC:lb, GOC:TermGenie, PMID:21543326] synonym: "protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0031252 ! has target end location cell leading edge relationship: RO:0002339 GO:0031252 ! has target end location cell leading edge created_by: jl creation_date: 2013-10-22T12:36:07Z [Term] id: GO:1902473 name: regulation of protein localization to synapse def: "Any process that modulates the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "regulation of protein localisation to synapse" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035418 ! regulates protein localization to synapse relationship: RO:0002211 GO:0035418 ! regulates protein localization to synapse created_by: kmv creation_date: 2013-10-25T15:09:09Z [Term] id: GO:1902474 name: positive regulation of protein localization to synapse def: "Any process that activates or increases the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "activation of protein localisation to synapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization to synapse" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to synapse" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035418 ! positively regulates protein localization to synapse relationship: RO:0002213 GO:0035418 ! positively regulates protein localization to synapse created_by: kmv creation_date: 2013-10-25T15:09:18Z [Term] id: GO:1902484 name: Sertoli cell apoptotic process def: "Any apoptotic process in a Sertoli cell." [GOC:ic, GOC:TermGenie, PMID:17761895] synonym: "Sertoli cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000216 ! occurs in Sertoli cell relationship: BFO:0000066 CL:0000216 ! occurs in Sertoli cell property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2013-11-06T11:27:34Z [Term] id: GO:1902488 name: cholangiocyte apoptotic process def: "Any apoptotic process in a cholangiocyte." [GOC:TermGenie, PMID:22961800] synonym: "cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:1000488 ! occurs in cholangiocyte relationship: BFO:0000066 CL:1000488 ! occurs in cholangiocyte property_value: RO:0002161 NCBITaxon:4751 created_by: cls creation_date: 2013-11-12T15:30:08Z [Term] id: GO:1902489 name: hepatoblast apoptotic process def: "Any apoptotic process in a hepatoblast." [GOC:TermGenie, PMID:22412967] synonym: "hepatoblast apoptosis" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0005026 ! occurs in hepatoblast relationship: BFO:0000066 CL:0005026 ! occurs in hepatoblast property_value: RO:0002161 NCBITaxon:4896 created_by: cls creation_date: 2013-11-12T17:02:52Z [Term] id: GO:1902490 name: regulation of sperm capacitation def: "Any process that modulates the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "regulation of sperm activation" RELATED [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048240 ! regulates sperm capacitation relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0048240 ! regulates sperm capacitation property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: hjd creation_date: 2013-11-12T21:17:03Z [Term] id: GO:1902491 name: negative regulation of sperm capacitation def: "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "down regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "down regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "down-regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "down-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "downregulation of sperm activation" RELATED [GOC:TermGenie] synonym: "downregulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "inhibition of sperm activation" RELATED [GOC:TermGenie] synonym: "inhibition of sperm capacitation" NARROW [GOC:TermGenie] synonym: "negative regulation of sperm activation" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048240 ! negatively regulates sperm capacitation relationship: RO:0002212 GO:0048240 ! negatively regulates sperm capacitation property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: hjd creation_date: 2013-11-12T21:17:12Z [Term] id: GO:1902492 name: positive regulation of sperm capacitation def: "Any process that activates or increases the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "activation of sperm activation" RELATED [GOC:TermGenie] synonym: "activation of sperm capacitation" NARROW [GOC:TermGenie] synonym: "positive regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "up-regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "upregulation of sperm activation" RELATED [GOC:TermGenie] synonym: "upregulation of sperm capacitation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048240 ! positively regulates sperm capacitation relationship: RO:0002213 GO:0048240 ! positively regulates sperm capacitation property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: hjd creation_date: 2013-11-12T21:17:21Z [Term] id: GO:1902494 name: catalytic complex def: "A protein complex which is capable of catalytic activity." [GOC:bhm, GOC:TermGenie, PMID:8077207] subset: goslim_metagenomics synonym: "enzyme complex" EXACT [GOC:bhm, GOC:jl] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0003824 ! catalytic activity relationship: capable_of GO:0003824 ! catalytic activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19980" xsd:anyURI created_by: bhm creation_date: 2013-11-13T16:18:47Z [Term] id: GO:1902495 name: transmembrane transporter complex def: "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other." [GOC:bhm, GOC:TermGenie, PMID:18024586] is_a: GO:0098796 ! membrane protein complex is_a: GO:1990351 ! transporter complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0022857 ! transmembrane transporter activity relationship: capable_of GO:0022857 ! transmembrane transporter activity created_by: bhm creation_date: 2013-11-13T16:23:04Z [Term] id: GO:1902513 name: regulation of organelle transport along microtubule def: "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." [GOC:dph, GOC:TermGenie, PMID:21147087] synonym: "regulation of microtubule-based organelle localization" EXACT [GOC:TermGenie] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072384 ! regulates organelle transport along microtubule relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0072384 ! regulates organelle transport along microtubule created_by: dph creation_date: 2013-11-15T20:15:17Z [Term] id: GO:1902531 name: regulation of intracellular signal transduction alt_id: GO:0010627 def: "Any process that modulates the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "regulation of intracellular protein kinase cascade" NARROW [] synonym: "regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035556 ! regulates intracellular signal transduction relationship: RO:0002211 GO:0035556 ! regulates intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:32:52Z [Term] id: GO:1902532 name: negative regulation of intracellular signal transduction alt_id: GO:0010741 def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "down regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "down regulation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "down regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "down regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "down regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "down-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "down-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "down-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down-regulation of signal transmission via intracellular cascade" RELATED [GOC:TermGenie] synonym: "downregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "downregulation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "downregulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "downregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "downregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signal transduction" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling chain" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "inhibition of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "inhibition of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "negative regulation of intracellular protein kinase cascade" EXACT [] synonym: "negative regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "negative regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "negative regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "negative regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035556 ! negatively regulates intracellular signal transduction relationship: RO:0002212 GO:0035556 ! negatively regulates intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:33:01Z [Term] id: GO:1902533 name: positive regulation of intracellular signal transduction alt_id: GO:0010740 def: "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." [GOC:BHF, GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "activation of intracellular signal transduction" NARROW [GOC:TermGenie] synonym: "activation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling chain" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "activation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "activation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "positive regulation of intracellular protein kinase cascade" NARROW [] synonym: "positive regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "positive regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "positive regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "positive regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "positive regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "positive regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "up regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "up regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "up regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "up-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "up-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "up-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up-regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "upregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "upregulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "upregulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "upregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "upregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035556 ! positively regulates intracellular signal transduction relationship: RO:0002213 GO:0035556 ! positively regulates intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:33:10Z [Term] id: GO:1902570 name: protein localization to nucleolus def: "A process in which a protein is transported to, or maintained in, a location within a nucleolus." [GOC:TermGenie, PMID:22809626] synonym: "protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005730 ! has target end location nucleolus relationship: RO:0002339 GO:0005730 ! has target end location nucleolus created_by: mah creation_date: 2013-12-10T16:25:28Z [Term] id: GO:1902679 name: negative regulation of RNA biosynthetic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "down regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of RNA anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of RNA biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of RNA biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of RNA formation" NARROW [GOC:TermGenie] synonym: "inhibition of RNA synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0051253 ! negative regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032774 ! negatively regulates RNA biosynthetic process relationship: RO:0002212 GO:0032774 ! negatively regulates RNA biosynthetic process created_by: jl creation_date: 2014-02-05T16:32:01Z [Term] id: GO:1902680 name: positive regulation of RNA biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "activation of RNA anabolism" NARROW [GOC:TermGenie] synonym: "activation of RNA biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of RNA biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of RNA formation" NARROW [GOC:TermGenie] synonym: "activation of RNA synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "upregulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0051254 ! positive regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032774 ! positively regulates RNA biosynthetic process relationship: RO:0002213 GO:0032774 ! positively regulates RNA biosynthetic process created_by: jl creation_date: 2014-02-05T16:32:10Z [Term] id: GO:1902692 name: regulation of neuroblast proliferation def: "Any process that modulates the frequency, rate or extent of neuroblast proliferation." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:21168496] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007405 ! regulates neuroblast proliferation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0007405 ! regulates neuroblast proliferation created_by: rl creation_date: 2014-02-18T10:03:31Z [Term] id: GO:1902738 name: regulation of chondrocyte differentiation involved in endochondral bone morphogenesis def: "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:8662546] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:1903010 ! regulation of bone development is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003413 ! regulates chondrocyte differentiation involved in endochondral bone morphogenesis relationship: RO:0002211 GO:0003413 ! regulates chondrocyte differentiation involved in endochondral bone morphogenesis created_by: mr creation_date: 2014-02-26T15:36:15Z [Term] id: GO:1902742 name: apoptotic process involved in development def: "Any apoptotic process that is involved in anatomical structure development." [GO_REF:0000060, GOC:mtg_apoptosis, GOC:pg, GOC:TermGenie] synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic process involved in anatomical structure development" EXACT [] synonym: "apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0048856 ! anatomical structure development relationship: part_of GO:0048856 ! anatomical structure development property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2014-02-28T13:09:43Z [Term] id: GO:1902761 name: positive regulation of chondrocyte development def: "Any process that activates or increases the frequency, rate or extent of chondrocyte development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] synonym: "activation of chondrocyte development" NARROW [GOC:TermGenie] synonym: "up regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "up-regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "upregulation of chondrocyte development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0032332 ! positive regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002063 ! positively regulates chondrocyte development relationship: RO:0002213 GO:0002063 ! positively regulates chondrocyte development created_by: mr creation_date: 2014-03-07T17:45:55Z [Term] id: GO:1902809 name: regulation of skeletal muscle fiber differentiation def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098528 ! regulates skeletal muscle fiber differentiation relationship: RO:0002211 GO:0098528 ! regulates skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:26Z [Term] id: GO:1902810 name: negative regulation of skeletal muscle fiber differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "down regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] is_a: GO:0010832 ! negative regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001015 ! negative regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098528 ! negatively regulates skeletal muscle fiber differentiation relationship: RO:0002212 GO:0098528 ! negatively regulates skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:32Z [Term] id: GO:1902811 name: positive regulation of skeletal muscle fiber differentiation def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "activation of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] is_a: GO:0010831 ! positive regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001016 ! positive regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098528 ! positively regulates skeletal muscle fiber differentiation relationship: RO:0002213 GO:0098528 ! positively regulates skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:38Z [Term] id: GO:1902816 name: regulation of protein localization to microtubule def: "Any process that modulates the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035372 ! regulates protein localization to microtubule relationship: RO:0002211 GO:0035372 ! regulates protein localization to microtubule created_by: tb creation_date: 2014-03-27T22:07:12Z [Term] id: GO:1902817 name: negative regulation of protein localization to microtubule def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "down regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to microtubule" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to microtubule" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:1902816 ! regulation of protein localization to microtubule is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035372 ! negatively regulates protein localization to microtubule relationship: RO:0002212 GO:0035372 ! negatively regulates protein localization to microtubule created_by: tb creation_date: 2014-03-27T22:07:18Z [Term] id: GO:1902838 name: regulation of nuclear migration along microtubule def: "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "regulation of nuclear movement, microtubule-mediated" BROAD [GOC:TermGenie] synonym: "regulation of nucleus migration" BROAD [GOC:TermGenie] synonym: "regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030473 ! regulates nuclear migration along microtubule relationship: RO:0002211 GO:0030473 ! regulates nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:23Z [Term] id: GO:1902839 name: negative regulation of nuclear migration along microtubule def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "down regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear migration along microtubule" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "inhibition of transport of nucleus by microtubules" NARROW [GOC:TermGenie] synonym: "inhibition of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030473 ! negatively regulates nuclear migration along microtubule relationship: RO:0002212 GO:0030473 ! negatively regulates nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:29Z [Term] id: GO:1902840 name: positive regulation of nuclear migration along microtubule def: "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "activation of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] synonym: "activation of nuclear migration along microtubule" NARROW [GOC:TermGenie] synonym: "activation of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "activation of transport of nucleus by microtubules" NARROW [GOC:TermGenie] synonym: "activation of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "positive regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030473 ! positively regulates nuclear migration along microtubule relationship: RO:0002213 GO:0030473 ! positively regulates nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:35Z [Term] id: GO:1902850 name: microtubule cytoskeleton organization involved in mitosis def: "Any microtubule cytoskeleton organization that is involved in mitosis." [GO_REF:0000060, GOC:TermGenie, PMID:18799626] synonym: "microtubule cytoskeleton organisation involved in mitosis" EXACT [GOC:TermGenie] synonym: "microtubule cytoskeleton organization and biogenesis involved in mitosis" RELATED [GOC:TermGenie] synonym: "microtubule dynamics involved in mitosis" EXACT [GOC:TermGenie] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000226 ! microtubule cytoskeleton organization intersection_of: part_of GO:0000278 ! mitotic cell cycle created_by: vw creation_date: 2014-04-02T14:19:38Z [Term] id: GO:1902863 name: regulation of embryonic camera-type eye development def: "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0031076 ! regulates embryonic camera-type eye development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0031076 ! regulates embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:00Z [Term] id: GO:1902864 name: negative regulation of embryonic camera-type eye development def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "inhibition of embryonic camera-type eye development" NARROW [GOC:TermGenie] synonym: "inhibition of embryonic eye development" NARROW [GOC:TermGenie] synonym: "negative regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0031076 ! negatively regulates embryonic camera-type eye development relationship: RO:0002212 GO:0031076 ! negatively regulates embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:06Z [Term] id: GO:1902865 name: positive regulation of embryonic camera-type eye development def: "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of embryonic camera-type eye development" NARROW [GOC:TermGenie] synonym: "activation of embryonic eye development" NARROW [GOC:TermGenie] synonym: "positive regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0031076 ! positively regulates embryonic camera-type eye development relationship: RO:0002213 GO:0031076 ! positively regulates embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:12Z [Term] id: GO:1902866 name: regulation of retina development in camera-type eye def: "Any process that modulates the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "regulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060041 ! regulates retina development in camera-type eye relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0060041 ! regulates retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:17Z [Term] id: GO:1902867 name: negative regulation of retina development in camera-type eye def: "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "down regulation of retinal development" RELATED [GOC:TermGenie] synonym: "down-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retinal development" RELATED [GOC:TermGenie] synonym: "downregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "downregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "downregulation of retinal development" RELATED [GOC:TermGenie] synonym: "inhibition of retina development in camera-style eye" NARROW [GOC:TermGenie] synonym: "inhibition of retina development in camera-type eye" NARROW [GOC:TermGenie] synonym: "inhibition of retinal development" RELATED [GOC:TermGenie] synonym: "negative regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "negative regulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060041 ! negatively regulates retina development in camera-type eye relationship: RO:0002212 GO:0060041 ! negatively regulates retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:23Z [Term] id: GO:1902868 name: positive regulation of retina development in camera-type eye def: "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of retina development in camera-style eye" NARROW [GOC:TermGenie] synonym: "activation of retina development in camera-type eye" NARROW [GOC:TermGenie] synonym: "activation of retinal development" RELATED [GOC:TermGenie] synonym: "positive regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "positive regulation of retinal development" RELATED [GOC:TermGenie] synonym: "up regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "up regulation of retinal development" RELATED [GOC:TermGenie] synonym: "up-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retinal development" RELATED [GOC:TermGenie] synonym: "upregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "upregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "upregulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060041 ! positively regulates retina development in camera-type eye relationship: RO:0002213 GO:0060041 ! positively regulates retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:29Z [Term] id: GO:1902875 name: regulation of embryonic pattern specification def: "Any process that modulates the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of embryonic pattern biosynthesis" BROAD [GOC:TermGenie] synonym: "regulation of embryonic pattern formation" BROAD [GOC:TermGenie] synonym: "regulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009880 ! regulates embryonic pattern specification relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0009880 ! regulates embryonic pattern specification property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mr creation_date: 2014-04-03T15:25:15Z [Term] id: GO:1902876 name: negative regulation of embryonic pattern specification def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "down regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "down-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "down-regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "downregulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "downregulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "inhibition of embryonic pattern specification" NARROW [GOC:TermGenie] synonym: "inhibition of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "negative regulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009880 ! negatively regulates embryonic pattern specification relationship: RO:0002212 GO:0009880 ! negatively regulates embryonic pattern specification property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mr creation_date: 2014-04-03T15:25:20Z [Term] id: GO:1902877 name: positive regulation of embryonic pattern specification def: "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of embryonic pattern specification" NARROW [GOC:TermGenie] synonym: "activation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "positive regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "up regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "up regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "up-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "up-regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "upregulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "upregulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009880 ! positively regulates embryonic pattern specification relationship: RO:0002213 GO:0009880 ! positively regulates embryonic pattern specification property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mr creation_date: 2014-04-03T15:25:26Z [Term] id: GO:1902903 name: regulation of supramolecular fiber organization def: "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "regulation of fibril organisation" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097435 ! regulates supramolecular fiber organization relationship: RO:0002211 GO:0097435 ! regulates supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:36Z [Term] id: GO:1902904 name: negative regulation of supramolecular fiber organization def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "down regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "down regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "down-regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "down-regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "downregulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "downregulation of fibril organization" RELATED [GOC:TermGenie] synonym: "inhibition of fibril organisation" NARROW [GOC:TermGenie] synonym: "inhibition of fibril organization" NARROW [GOC:TermGenie] synonym: "negative regulation of fibril organisation" RELATED [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097435 ! negatively regulates supramolecular fiber organization relationship: RO:0002212 GO:0097435 ! negatively regulates supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:42Z [Term] id: GO:1902905 name: positive regulation of supramolecular fiber organization def: "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "activation of fibril organisation" NARROW [GOC:TermGenie] synonym: "activation of fibril organization" NARROW [GOC:TermGenie] synonym: "positive regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "up-regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up-regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "upregulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "upregulation of fibril organization" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097435 ! positively regulates supramolecular fiber organization relationship: RO:0002213 GO:0097435 ! positively regulates supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:48Z [Term] id: GO:1902913 name: positive regulation of neuroepithelial cell differentiation def: "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16916506] synonym: "activation of neuroepithelial cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060563 ! positively regulates neuroepithelial cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002213 GO:0060563 ! positively regulates neuroepithelial cell differentiation created_by: mr creation_date: 2014-04-18T21:06:42Z [Term] id: GO:1903008 name: organelle disassembly def: "The disaggregation of an organelle into its constituent components." [GO_REF:0000079, GOC:TermGenie] synonym: "organelle degradation" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0043226 ! results in disassembly of organelle relationship: RO:0002590 GO:0043226 ! results in disassembly of organelle created_by: jl creation_date: 2014-05-13T12:36:03Z [Term] id: GO:1903010 name: regulation of bone development def: "Any process that modulates the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060348 ! regulates bone development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0060348 ! regulates bone development created_by: mr creation_date: 2014-05-13T22:41:53Z [Term] id: GO:1903011 name: negative regulation of bone development def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "down regulation of bone development" EXACT [GOC:TermGenie] synonym: "down-regulation of bone development" EXACT [GOC:TermGenie] synonym: "downregulation of bone development" EXACT [GOC:TermGenie] synonym: "inhibition of bone development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060348 ! negatively regulates bone development relationship: RO:0002212 GO:0060348 ! negatively regulates bone development created_by: mr creation_date: 2014-05-13T22:42:00Z [Term] id: GO:1903012 name: positive regulation of bone development def: "Any process that activates or increases the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "activation of bone development" NARROW [GOC:TermGenie] synonym: "up regulation of bone development" EXACT [GOC:TermGenie] synonym: "up-regulation of bone development" EXACT [GOC:TermGenie] synonym: "upregulation of bone development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060348 ! positively regulates bone development relationship: RO:0002213 GO:0060348 ! positively regulates bone development created_by: mr creation_date: 2014-05-13T22:42:06Z [Term] id: GO:1903018 name: regulation of glycoprotein metabolic process def: "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009100 ! regulates glycoprotein metabolic process relationship: RO:0002211 GO:0009100 ! regulates glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:19Z [Term] id: GO:1903019 name: negative regulation of glycoprotein metabolic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "down regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0051248 ! negative regulation of protein metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0009100 ! negatively regulates glycoprotein metabolic process relationship: RO:0002212 GO:0009100 ! negatively regulates glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:25Z [Term] id: GO:1903020 name: positive regulation of glycoprotein metabolic process def: "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "activation of glycoprotein metabolic process" NARROW [GOC:TermGenie] synonym: "activation of glycoprotein metabolism" NARROW [GOC:TermGenie] synonym: "positive regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0051247 ! positive regulation of protein metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009100 ! positively regulates glycoprotein metabolic process relationship: RO:0002213 GO:0009100 ! positively regulates glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:31Z [Term] id: GO:1903037 name: regulation of leukocyte cell-cell adhesion def: "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007159 ! regulates leukocyte cell-cell adhesion relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0007159 ! regulates leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:29:58Z [Term] id: GO:1903038 name: negative regulation of leukocyte cell-cell adhesion def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "down regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "inhibition of leukocyte adhesion" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte cell adhesion" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] synonym: "negative regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "negative regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022408 ! negative regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007159 ! negatively regulates leukocyte cell-cell adhesion relationship: RO:0002212 GO:0007159 ! negatively regulates leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:30:05Z [Term] id: GO:1903039 name: positive regulation of leukocyte cell-cell adhesion def: "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "activation of leukocyte adhesion" NARROW [GOC:TermGenie] synonym: "activation of leukocyte cell adhesion" NARROW [GOC:TermGenie] synonym: "activation of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] synonym: "positive regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "positive regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022409 ! positive regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007159 ! positively regulates leukocyte cell-cell adhesion relationship: RO:0002213 GO:0007159 ! positively regulates leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:30:15Z [Term] id: GO:1903045 name: neural crest cell migration involved in sympathetic nervous system development def: "Any neural crest cell migration that is involved in sympathetic nervous system development." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19325129] comment: Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development is_a: GO:1901166 ! neural crest cell migration involved in autonomic nervous system development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0048485 ! sympathetic nervous system development relationship: part_of GO:0048485 ! sympathetic nervous system development created_by: rl creation_date: 2014-05-22T07:06:02Z [Term] id: GO:1903046 name: meiotic cell cycle process def: "A process that is part of the meiotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] subset: gocheck_do_not_annotate subset: goslim_pombe is_a: GO:0022402 ! cell cycle process is_a: GO:0022414 ! reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0051321 ! meiotic cell cycle disjoint_from: GO:1903047 ! mitotic cell cycle process relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0051321 ! meiotic cell cycle created_by: jl creation_date: 2014-05-22T14:22:28Z [Term] id: GO:1903047 name: mitotic cell cycle process def: "A process that is part of the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] subset: gocheck_do_not_annotate is_a: GO:0022402 ! cell cycle process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0000278 ! mitotic cell cycle relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0000278 ! mitotic cell cycle created_by: jl creation_date: 2014-05-22T14:22:34Z [Term] id: GO:1903053 name: regulation of extracellular matrix organization def: "Any process that modulates the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030198 ! regulates extracellular matrix organization relationship: RO:0002211 GO:0030198 ! regulates extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:41Z [Term] id: GO:1903054 name: negative regulation of extracellular matrix organization def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "down regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of extracellular matrix organisation" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular matrix organization" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030198 ! negatively regulates extracellular matrix organization relationship: RO:0002212 GO:0030198 ! negatively regulates extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:47Z [Term] id: GO:1903055 name: positive regulation of extracellular matrix organization def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "activation of extracellular matrix organisation" NARROW [GOC:TermGenie] synonym: "activation of extracellular matrix organization" NARROW [GOC:TermGenie] synonym: "activation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030198 ! positively regulates extracellular matrix organization relationship: RO:0002213 GO:0030198 ! positively regulates extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:53Z [Term] id: GO:1903076 name: regulation of protein localization to plasma membrane alt_id: GO:0090003 alt_id: GO:1905963 def: "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "regulation of establishment of protein localization in plasma membrane" RELATED [] synonym: "regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] synonym: "regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein targeting to plasma membrane" RELATED [] synonym: "regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072659 ! regulates protein localization to plasma membrane relationship: RO:0002211 GO:0072659 ! regulates protein localization to plasma membrane created_by: tb creation_date: 2009-07-10T10:32:44Z [Term] id: GO:1903077 name: negative regulation of protein localization to plasma membrane alt_id: GO:0090005 alt_id: GO:1905964 def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "down regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "down regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "down-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "down-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "downregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "downregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "inhibition of protein localisation in plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein targeting to plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein-plasma membrane targeting" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "negative regulation of establishment of protein localization in plasma membrane" RELATED [] synonym: "negative regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "negative regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] synonym: "negative regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein targeting to plasma membrane" RELATED [] synonym: "negative regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072659 ! negatively regulates protein localization to plasma membrane relationship: RO:0002212 GO:0072659 ! negatively regulates protein localization to plasma membrane created_by: tb creation_date: 2014-05-29T17:10:16Z [Term] id: GO:1903078 name: positive regulation of protein localization to plasma membrane alt_id: GO:0090004 alt_id: GO:1905965 def: "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "activation of protein localisation in plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein targeting to plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein-plasma membrane targeting" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "positive regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "positive regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein targeting to plasma membrane" RELATED [] synonym: "positive regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "up regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "up regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "up-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "up-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "upregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "upregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072659 ! positively regulates protein localization to plasma membrane relationship: RO:0002213 GO:0072659 ! positively regulates protein localization to plasma membrane created_by: tb creation_date: 2009-07-10T10:34:17Z [Term] id: GO:1903115 name: regulation of actin filament-based movement def: "Any process that modulates the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] is_a: GO:0032970 ! regulation of actin filament-based process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030048 ! regulates actin filament-based movement relationship: RO:0002211 GO:0030048 ! regulates actin filament-based movement created_by: al creation_date: 2014-06-12T16:55:57Z [Term] id: GO:1903116 name: positive regulation of actin filament-based movement def: "Any process that activates or increases the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] synonym: "activation of actin filament-based movement" NARROW [GOC:TermGenie] synonym: "up regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "up-regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "upregulation of actin filament-based movement" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:1903115 ! regulation of actin filament-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030048 ! positively regulates actin filament-based movement relationship: RO:0002213 GO:0030048 ! positively regulates actin filament-based movement created_by: al creation_date: 2014-06-12T16:56:04Z [Term] id: GO:1903119 name: protein localization to actin cytoskeleton def: "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localisation to actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localization in actin cytoskeleton" EXACT [GOC:TermGenie] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0015629 ! has target end location actin cytoskeleton relationship: RO:0002339 GO:0015629 ! has target end location actin cytoskeleton created_by: mah creation_date: 2014-06-16T11:27:09Z [Term] id: GO:1903120 name: protein localization to actin filament bundle def: "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localisation to actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localization in actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localization to actin cable" RELATED [GOC:mah] is_a: GO:1903119 ! protein localization to actin cytoskeleton intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0032432 ! has target end location actin filament bundle relationship: RO:0002339 GO:0032432 ! has target end location actin filament bundle created_by: mah creation_date: 2014-06-16T11:27:16Z [Term] id: GO:1903131 name: mononuclear cell differentiation def: "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell." [CL:0000842, GO_REF:0000086, GOC:TermGenie, PMID:24759906] is_a: GO:0002521 ! leukocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: RO:0002315 CL:0000842 ! results in acquisition of features of mononuclear leukocyte relationship: RO:0002315 CL:0000842 ! results in acquisition of features of mononuclear leukocyte created_by: cls creation_date: 2014-06-25T15:47:09Z [Term] id: GO:1903224 name: regulation of endodermal cell differentiation def: "Any process that modulates the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035987 ! regulates endodermal cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0035987 ! regulates endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:35Z [Term] id: GO:1903225 name: negative regulation of endodermal cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "down regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of endoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of endodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035987 ! negatively regulates endodermal cell differentiation relationship: RO:0002212 GO:0035987 ! negatively regulates endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:41Z [Term] id: GO:1903226 name: positive regulation of endodermal cell differentiation def: "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "activation of endoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of endodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035987 ! positively regulates endodermal cell differentiation relationship: RO:0002213 GO:0035987 ! positively regulates endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:47Z [Term] id: GO:1903276 name: regulation of sodium ion export across plasma membrane alt_id: GO:1903273 def: "Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17095720] synonym: "regulation of sodium export" RELATED [GOC:TermGenie] synonym: "regulation of sodium ion export" RELATED [] synonym: "regulation of sodium ion export from cell" EXACT [] is_a: GO:1902305 ! regulation of sodium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0036376 ! regulates sodium ion export across plasma membrane relationship: RO:0002211 GO:0036376 ! regulates sodium ion export across plasma membrane created_by: rl creation_date: 2014-08-08T17:06:46Z [Term] id: GO:1903277 name: negative regulation of sodium ion export across plasma membrane alt_id: GO:1903274 def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17095720] synonym: "down regulation of sodium export" RELATED [GOC:TermGenie] synonym: "down regulation of sodium ion export" RELATED [GOC:TermGenie] synonym: "down regulation of sodium ion export from cell" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium export" RELATED [GOC:TermGenie] synonym: "down-regulation of sodium ion export" RELATED [GOC:TermGenie] synonym: "down-regulation of sodium ion export from cell" EXACT [GOC:TermGenie] synonym: "downregulation of sodium export" RELATED [GOC:TermGenie] synonym: "downregulation of sodium ion export" RELATED [GOC:TermGenie] synonym: "downregulation of sodium ion export from cell" EXACT [GOC:TermGenie] synonym: "inhibition of sodium export" NARROW [GOC:TermGenie] synonym: "inhibition of sodium ion export" NARROW [GOC:TermGenie] synonym: "inhibition of sodium ion export from cell" NARROW [GOC:TermGenie] synonym: "negative regulation of sodium export" RELATED [GOC:TermGenie] synonym: "negative regulation of sodium ion export" RELATED [] synonym: "negative regulation of sodium ion export from cell" EXACT [] is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport is_a: GO:1903276 ! regulation of sodium ion export across plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0036376 ! negatively regulates sodium ion export across plasma membrane relationship: RO:0002212 GO:0036376 ! negatively regulates sodium ion export across plasma membrane created_by: rl creation_date: 2014-08-08T17:10:22Z [Term] id: GO:1903278 name: positive regulation of sodium ion export across plasma membrane alt_id: GO:1903275 def: "Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17095720] synonym: "activation of sodium export" NARROW [GOC:TermGenie] synonym: "activation of sodium ion export" NARROW [GOC:TermGenie] synonym: "activation of sodium ion export from cell" NARROW [GOC:TermGenie] synonym: "positive regulation of sodium export" RELATED [GOC:TermGenie] synonym: "positive regulation of sodium ion export" RELATED [] synonym: "positive regulation of sodium ion export from cell" EXACT [] synonym: "up regulation of sodium export" RELATED [GOC:TermGenie] synonym: "up regulation of sodium ion export" RELATED [GOC:TermGenie] synonym: "up regulation of sodium ion export from cell" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium export" RELATED [GOC:TermGenie] synonym: "up-regulation of sodium ion export" RELATED [GOC:TermGenie] synonym: "up-regulation of sodium ion export from cell" EXACT [GOC:TermGenie] synonym: "upregulation of sodium export" RELATED [GOC:TermGenie] synonym: "upregulation of sodium ion export" RELATED [GOC:TermGenie] synonym: "upregulation of sodium ion export from cell" EXACT [GOC:TermGenie] is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport is_a: GO:1903276 ! regulation of sodium ion export across plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0036376 ! positively regulates sodium ion export across plasma membrane relationship: RO:0002213 GO:0036376 ! positively regulates sodium ion export across plasma membrane created_by: rl creation_date: 2014-08-08T17:10:30Z [Term] id: GO:1903292 name: protein localization to Golgi membrane def: "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane." [GO_REF:0000087, GOC:TermGenie, PMID:11378902] synonym: "protein localisation in Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localization in Golgi membrane" EXACT [GOC:TermGenie] is_a: GO:0034067 ! protein localization to Golgi apparatus is_a: GO:0072657 ! protein localization to membrane intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0000139 ! has target end location Golgi membrane relationship: RO:0002339 GO:0000139 ! has target end location Golgi membrane created_by: mah creation_date: 2014-08-12T14:22:31Z [Term] id: GO:1903326 name: regulation of tRNA metabolic process def: "Any process that modulates the frequency, rate or extent of tRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "regulation of tRNA metabolism" EXACT [GOC:TermGenie] is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006399 ! regulates tRNA metabolic process relationship: RO:0002211 GO:0006399 ! regulates tRNA metabolic process created_by: vw creation_date: 2014-08-18T13:08:50Z [Term] id: GO:1903327 name: negative regulation of tRNA metabolic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of tRNA metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tRNA metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tRNA metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tRNA metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tRNA metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tRNA metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tRNA metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of tRNA metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of tRNA metabolism" EXACT [GOC:TermGenie] is_a: GO:0051253 ! negative regulation of RNA metabolic process is_a: GO:1903326 ! regulation of tRNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006399 ! negatively regulates tRNA metabolic process relationship: RO:0002212 GO:0006399 ! negatively regulates tRNA metabolic process created_by: vw creation_date: 2014-08-18T13:08:58Z [Term] id: GO:1903328 name: positive regulation of tRNA metabolic process def: "Any process that activates or increases the frequency, rate or extent of tRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "activation of tRNA metabolic process" NARROW [GOC:TermGenie] synonym: "activation of tRNA metabolism" NARROW [GOC:TermGenie] synonym: "positive regulation of tRNA metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tRNA metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tRNA metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tRNA metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tRNA metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tRNA metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tRNA metabolism" EXACT [GOC:TermGenie] is_a: GO:0051254 ! positive regulation of RNA metabolic process is_a: GO:1903326 ! regulation of tRNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006399 ! positively regulates tRNA metabolic process relationship: RO:0002213 GO:0006399 ! positively regulates tRNA metabolic process created_by: vw creation_date: 2014-08-18T13:09:06Z [Term] id: GO:1903335 name: regulation of vacuolar transport def: "Any process that modulates the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007034 ! regulates vacuolar transport relationship: RO:0002211 GO:0007034 ! regulates vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:04Z [Term] id: GO:1903336 name: negative regulation of vacuolar transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "down-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "downregulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "inhibition of vacuolar transport" NARROW [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007034 ! negatively regulates vacuolar transport relationship: RO:0002212 GO:0007034 ! negatively regulates vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:11Z [Term] id: GO:1903337 name: positive regulation of vacuolar transport def: "Any process that activates or increases the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "activation of vacuolar transport" NARROW [GOC:TermGenie] synonym: "up regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "up-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "upregulation of vacuolar transport" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007034 ! positively regulates vacuolar transport relationship: RO:0002213 GO:0007034 ! positively regulates vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:19Z [Term] id: GO:1903353 name: regulation of nucleus organization def: "Any process that modulates the frequency, rate or extent of nucleus organization." [GO_REF:0000058, GOC:TermGenie, PMID:16943282] synonym: "regulation of nuclear morphology" RELATED [GOC:TermGenie] synonym: "regulation of nuclear organisation" EXACT [GOC:TermGenie] synonym: "regulation of nuclear organization" EXACT [GOC:TermGenie] synonym: "regulation of nuclear organization and biogenesis" RELATED [GOC:TermGenie] synonym: "regulation of nucleus organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006997 ! regulates nucleus organization relationship: RO:0002211 GO:0006997 ! regulates nucleus organization created_by: hjd creation_date: 2014-08-20T19:36:16Z [Term] id: GO:1903358 name: regulation of Golgi organization def: "Any process that modulates the frequency, rate or extent of Golgi organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:17562788] synonym: "regulation of Golgi organisation" EXACT [GOC:TermGenie] synonym: "regulation of Golgi organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007030 ! regulates Golgi organization relationship: RO:0002211 GO:0007030 ! regulates Golgi organization created_by: als creation_date: 2014-08-21T10:22:22Z [Term] id: GO:1903375 name: facioacoustic ganglion development def: "The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure." [GO_REF:0000094, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] synonym: "acoustico-facial VII-VIII ganglion complex development" EXACT [UBERON:0012175] synonym: "acousticofacial ganglion development" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion complex VII-VIII development" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion development" EXACT [GOC:TermGenie] synonym: "facio-acoustic VII-VIII ganglion complex development" EXACT [GOC:TermGenie] is_a: GO:0061550 ! cranial ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0012175 ! results in development of acoustico-facial VII-VIII ganglion complex relationship: RO:0002296 UBERON:0012175 ! results in development of acoustico-facial VII-VIII ganglion complex created_by: bf creation_date: 2014-08-26T12:40:36Z [Term] id: GO:1903379 name: regulation of mitotic chromosome condensation def: "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0060623 ! regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007076 ! regulates mitotic chromosome condensation relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0007076 ! regulates mitotic chromosome condensation created_by: al creation_date: 2014-08-26T13:57:13Z [Term] id: GO:1903380 name: positive regulation of mitotic chromosome condensation def: "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] synonym: "activation of mitotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "up regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903379 ! regulation of mitotic chromosome condensation is_a: GO:1905821 ! positive regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007076 ! positively regulates mitotic chromosome condensation relationship: RO:0002213 GO:0007076 ! positively regulates mitotic chromosome condensation created_by: al creation_date: 2014-08-26T13:57:29Z [Term] id: GO:1903412 name: response to bile acid def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] is_a: GO:0033993 ! response to lipid is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:3098 ! has primary input bile acid relationship: RO:0004009 CHEBI:3098 ! has primary input bile acid created_by: rl creation_date: 2014-09-03T12:45:43Z [Term] id: GO:1903413 name: cellular response to bile acid def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] is_a: GO:0071396 ! cellular response to lipid is_a: GO:1901701 ! cellular response to oxygen-containing compound is_a: GO:1903412 ! response to bile acid intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:3098 ! has primary input bile acid created_by: rl creation_date: 2014-09-03T12:45:51Z [Term] id: GO:1903429 name: regulation of cell maturation def: "Any process that modulates the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "regulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048469 ! regulates cell maturation relationship: RO:0002211 GO:0048469 ! regulates cell maturation created_by: jl creation_date: 2014-09-15T13:31:23Z [Term] id: GO:1903430 name: negative regulation of cell maturation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "down regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "down regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "down-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "downregulation of cell maturation" EXACT [GOC:TermGenie] synonym: "downregulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "inhibition of cell maturation" NARROW [GOC:TermGenie] synonym: "inhibition of functional differentiation" RELATED [GOC:TermGenie] synonym: "negative regulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048469 ! negatively regulates cell maturation relationship: RO:0002212 GO:0048469 ! negatively regulates cell maturation created_by: jl creation_date: 2014-09-15T13:31:32Z [Term] id: GO:1903431 name: positive regulation of cell maturation def: "Any process that activates or increases the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "activation of cell maturation" NARROW [GOC:TermGenie] synonym: "activation of functional differentiation" RELATED [GOC:TermGenie] synonym: "positive regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "up regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "up regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "up-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "upregulation of cell maturation" EXACT [GOC:TermGenie] synonym: "upregulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048469 ! positively regulates cell maturation relationship: RO:0002213 GO:0048469 ! positively regulates cell maturation created_by: jl creation_date: 2014-09-15T13:31:41Z [Term] id: GO:1903441 name: protein localization to ciliary membrane def: "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane." [GO_REF:0000087, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22139371] synonym: "protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0060170 ! has target end location ciliary membrane relationship: RO:0002339 GO:0060170 ! has target end location ciliary membrane property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: pr creation_date: 2014-09-16T15:15:39Z [Term] id: GO:1903522 name: regulation of blood circulation def: "Any process that modulates the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "regulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008015 ! regulates blood circulation relationship: RO:0002211 GO:0008015 ! regulates blood circulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mr creation_date: 2014-10-06T18:38:56Z [Term] id: GO:1903523 name: negative regulation of blood circulation def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "down regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "down regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "down-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "downregulation of blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "inhibition of blood circulation" NARROW [GOC:TermGenie] synonym: "inhibition of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "negative regulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008015 ! negatively regulates blood circulation relationship: RO:0002212 GO:0008015 ! negatively regulates blood circulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mr creation_date: 2014-10-06T18:39:05Z [Term] id: GO:1903524 name: positive regulation of blood circulation def: "Any process that activates or increases the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "activation of blood circulation" NARROW [GOC:TermGenie] synonym: "activation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "positive regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "up regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "up-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "upregulation of blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008015 ! positively regulates blood circulation relationship: RO:0002213 GO:0008015 ! positively regulates blood circulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: mr creation_date: 2014-10-06T18:39:13Z [Term] id: GO:1903530 name: regulation of secretion by cell def: "Any process that modulates the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032940 ! regulates secretion by cell relationship: RO:0002211 GO:0032940 ! regulates secretion by cell created_by: pm creation_date: 2014-10-08T13:24:59Z [Term] id: GO:1903531 name: negative regulation of secretion by cell def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "down regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "downregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "inhibition of cellular secretion" NARROW [GOC:TermGenie] synonym: "inhibition of secretion by cell" NARROW [GOC:TermGenie] synonym: "negative regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051048 ! negative regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032940 ! negatively regulates secretion by cell relationship: RO:0002212 GO:0032940 ! negatively regulates secretion by cell created_by: pm creation_date: 2014-10-08T13:25:08Z [Term] id: GO:1903532 name: positive regulation of secretion by cell def: "Any process that activates or increases the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "activation of cellular secretion" NARROW [GOC:TermGenie] synonym: "activation of secretion by cell" NARROW [GOC:TermGenie] synonym: "positive regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "upregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion by cell" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051047 ! positive regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032940 ! positively regulates secretion by cell relationship: RO:0002213 GO:0032940 ! positively regulates secretion by cell created_by: pm creation_date: 2014-10-08T13:25:17Z [Term] id: GO:1903537 name: meiotic cell cycle process involved in oocyte maturation def: "Any meiotic cell cycle process that is involved in oocyte maturation." [GO_REF:0000060, GOC:jz, GOC:TermGenie, PMID:25212395] synonym: "meiosis involved in oocyte maturation" BROAD [] is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:1903046 ! meiotic cell cycle process intersection_of: part_of GO:0001556 ! oocyte maturation relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0001556 ! oocyte maturation created_by: pr creation_date: 2014-10-09T10:46:14Z [Term] id: GO:1903538 name: regulation of meiotic cell cycle process involved in oocyte maturation def: "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25212395] synonym: "regulation of meiosis involved in oocyte maturation" BROAD [GOC:TermGenie] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1903537 ! regulates meiotic cell cycle process involved in oocyte maturation relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:1903537 ! regulates meiotic cell cycle process involved in oocyte maturation created_by: pr creation_date: 2014-10-09T10:52:38Z [Term] id: GO:1903541 name: regulation of exosomal secretion def: "Any process that modulates the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0017157 ! regulation of exocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990182 ! regulates exosomal secretion relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:1990182 ! regulates exosomal secretion property_value: RO:0002161 NCBITaxon:4890 created_by: pga creation_date: 2014-10-14T11:38:52Z [Term] id: GO:1903542 name: negative regulation of exosomal secretion def: "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "down regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "down-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "downregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "inhibition of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "inhibition of exosomal secretion" NARROW [GOC:TermGenie] synonym: "inhibition of exosomal secretory pathway" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] synonym: "inhibition of secretion of exosome" NARROW [GOC:TermGenie] synonym: "negative regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "negative regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "negative regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0045920 ! negative regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990182 ! negatively regulates exosomal secretion relationship: RO:0002212 GO:1990182 ! negatively regulates exosomal secretion property_value: RO:0002161 NCBITaxon:4890 created_by: pga creation_date: 2014-10-14T11:39:02Z [Term] id: GO:1903543 name: positive regulation of exosomal secretion def: "Any process that activates or increases the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "activation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "activation of exosomal secretion" NARROW [GOC:TermGenie] synonym: "activation of exosomal secretory pathway" NARROW [GOC:TermGenie] synonym: "activation of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] synonym: "activation of secretion of exosome" NARROW [GOC:TermGenie] synonym: "positive regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "positive regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "positive regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "positive regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "up regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "up-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "upregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0045921 ! positive regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990182 ! positively regulates exosomal secretion relationship: RO:0002213 GO:1990182 ! positively regulates exosomal secretion property_value: RO:0002161 NCBITaxon:4890 created_by: pga creation_date: 2014-10-14T11:39:10Z [Term] id: GO:1903551 name: regulation of extracellular exosome assembly def: "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071971 ! regulates extracellular exosome assembly relationship: RO:0002211 GO:0071971 ! regulates extracellular exosome assembly property_value: RO:0002161 NCBITaxon:4890 created_by: pga creation_date: 2014-10-20T15:37:25Z [Term] id: GO:1903552 name: negative regulation of extracellular exosome assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "inhibition of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071971 ! negatively regulates extracellular exosome assembly relationship: RO:0002212 GO:0071971 ! negatively regulates extracellular exosome assembly property_value: RO:0002161 NCBITaxon:4890 created_by: pga creation_date: 2014-10-20T15:37:33Z [Term] id: GO:1903553 name: positive regulation of extracellular exosome assembly def: "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "activation of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] synonym: "positive regulation of extracellular vesicular exosome assembly" RELATED [GOC:vesicles] synonym: "up regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071971 ! positively regulates extracellular exosome assembly relationship: RO:0002213 GO:0071971 ! positively regulates extracellular exosome assembly property_value: RO:0002161 NCBITaxon:4890 created_by: pga creation_date: 2014-10-20T15:37:42Z [Term] id: GO:1903561 name: extracellular vesicle def: "Any vesicle that is part of the extracellular region." [GO_REF:0000064, GOC:pm, GOC:TermGenie, PMID:24769233] synonym: "microparticle" RELATED [GOC:vesicles] is_a: GO:0031982 ! vesicle is_a: GO:0065010 ! extracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005576 ! extracellular region created_by: jl creation_date: 2014-10-22T14:26:11Z [Term] id: GO:1903564 name: regulation of protein localization to cilium def: "Any process that modulates the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061512 ! regulates protein localization to cilium relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0061512 ! regulates protein localization to cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2014-10-24T20:58:11Z [Term] id: GO:1903565 name: negative regulation of protein localization to cilium def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "inhibition of protein localization to cilium" NARROW [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061512 ! negatively regulates protein localization to cilium relationship: RO:0002212 GO:0061512 ! negatively regulates protein localization to cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2014-10-24T20:58:20Z [Term] id: GO:1903566 name: positive regulation of protein localization to cilium def: "Any process that activates or increases the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "activation of protein localization to cilium" NARROW [GOC:TermGenie] synonym: "up regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cilium" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061512 ! positively regulates protein localization to cilium relationship: RO:0002213 GO:0061512 ! positively regulates protein localization to cilium property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2014-10-24T20:58:28Z [Term] id: GO:1903567 name: regulation of protein localization to ciliary membrane def: "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1903441 ! regulates protein localization to ciliary membrane relationship: RO:0002211 GO:1903441 ! regulates protein localization to ciliary membrane property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2014-10-24T21:32:51Z [Term] id: GO:1903568 name: negative regulation of protein localization to ciliary membrane def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to ciliary membrane" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903565 ! negative regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1903441 ! negatively regulates protein localization to ciliary membrane relationship: RO:0002212 GO:1903441 ! negatively regulates protein localization to ciliary membrane property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2014-10-24T21:32:59Z [Term] id: GO:1903569 name: positive regulation of protein localization to ciliary membrane def: "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "activation of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to ciliary membrane" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903566 ! positive regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1903441 ! positively regulates protein localization to ciliary membrane relationship: RO:0002213 GO:1903441 ! positively regulates protein localization to ciliary membrane property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2014-10-24T21:33:08Z [Term] id: GO:1903697 name: negative regulation of microvillus assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "down regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "down regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "downregulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of microvillus assembly" NARROW [GOC:TermGenie] synonym: "inhibition of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of microvillus biogenesis" RELATED [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030033 ! negatively regulates microvillus assembly relationship: RO:0002212 GO:0030033 ! negatively regulates microvillus assembly created_by: als creation_date: 2014-12-03T11:45:08Z [Term] id: GO:1903698 name: positive regulation of microvillus assembly def: "Any process that activates or increases the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "activation of microvillus assembly" NARROW [GOC:TermGenie] synonym: "activation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "up regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "upregulation of microvillus biogenesis" RELATED [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030033 ! positively regulates microvillus assembly relationship: RO:0002213 GO:0030033 ! positively regulates microvillus assembly created_by: als creation_date: 2014-12-03T11:45:17Z [Term] id: GO:1903701 name: substantia propria of cornea development def: "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12556382] synonym: "corneal stroma development" EXACT [GOC:TermGenie] synonym: "stroma of cornea development" EXACT [GOC:TermGenie] synonym: "substantia propria development" RELATED [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001777 ! results in development of substantia propria of cornea relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0001777 ! results in development of substantia propria of cornea created_by: cls creation_date: 2014-12-03T13:12:09Z [Term] id: GO:1903702 name: esophagus development def: "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0-683-40008-8] synonym: "esophageal development" EXACT [MGI:csmith] synonym: "gullet development" EXACT [GOC:TermGenie] synonym: "oesophagus development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001043 ! results in development of esophagus relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0001043 ! results in development of esophagus created_by: cls creation_date: 2014-12-03T14:41:30Z [Term] id: GO:1903706 name: regulation of hemopoiesis def: "Any process that modulates the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030097 ! regulates hemopoiesis relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0030097 ! regulates hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:13Z [Term] id: GO:1903707 name: negative regulation of hemopoiesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "down regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "inhibition of blood cell biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of blood cell formation" NARROW [GOC:TermGenie] synonym: "inhibition of haemopoiesis" NARROW [GOC:TermGenie] synonym: "inhibition of hematopoiesis" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoiesis" NARROW [GOC:TermGenie] synonym: "negative regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030097 ! negatively regulates hemopoiesis relationship: RO:0002212 GO:0030097 ! negatively regulates hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:21Z [Term] id: GO:1903708 name: positive regulation of hemopoiesis def: "Any process that activates or increases the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "activation of blood cell biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of blood cell formation" NARROW [GOC:TermGenie] synonym: "activation of haemopoiesis" NARROW [GOC:TermGenie] synonym: "activation of hematopoiesis" NARROW [GOC:TermGenie] synonym: "activation of hemopoiesis" NARROW [GOC:TermGenie] synonym: "positive regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030097 ! positively regulates hemopoiesis relationship: RO:0002213 GO:0030097 ! positively regulates hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:30Z [Term] id: GO:1903709 name: uterine gland development def: "The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:23619340] synonym: "endometrial gland development" EXACT [GOC:TermGenie] synonym: "endometrium gland development" EXACT [GOC:TermGenie] synonym: "glandulae uterinae development" RELATED [GOC:TermGenie] synonym: "glandular part of endometrium development" RELATED [GOC:TermGenie] synonym: "set of uterine glands development" RELATED [GOC:TermGenie] synonym: "uterine glands development" EXACT [GOC:TermGenie] synonym: "uterine glands set development" EXACT [GOC:TermGenie] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002451 ! results in development of endometrial gland relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002296 UBERON:0002451 ! results in development of endometrial gland created_by: cls creation_date: 2014-12-04T18:57:21Z [Term] id: GO:1903729 name: regulation of plasma membrane organization def: "Any process that modulates the frequency, rate or extent of plasma membrane organization." [GO_REF:0000058, GOC:TermGenie, PMID:24514900] synonym: "regulation of plasma membrane organisation" EXACT [GOC:TermGenie] synonym: "regulation of plasma membrane organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007009 ! regulates plasma membrane organization relationship: RO:0002211 GO:0007009 ! regulates plasma membrane organization created_by: al creation_date: 2014-12-10T18:59:44Z [Term] id: GO:1903778 name: protein localization to vacuolar membrane def: "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane." [GO_REF:0000087, GOC:TermGenie, PMID:25378562] synonym: "protein localisation in vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localization in vacuolar membrane" EXACT [GOC:TermGenie] is_a: GO:0072657 ! protein localization to membrane is_a: GO:0072665 ! protein localization to vacuole intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005774 ! has target end location vacuolar membrane relationship: RO:0002339 GO:0005774 ! has target end location vacuolar membrane created_by: mah creation_date: 2015-01-07T13:15:54Z [Term] id: GO:1903779 name: regulation of cardiac conduction def: "Any process that modulates the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] xref: Reactome:R-HSA-5578768 "Physiological factors" xref: Reactome:R-HSA-5578775 "Ion homeostasis" is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061337 ! regulates cardiac conduction relationship: RO:0002211 GO:0061337 ! regulates cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: rph creation_date: 2015-01-07T13:20:11Z [Term] id: GO:1903780 name: negative regulation of cardiac conduction def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "down regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac conduction" NARROW [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061337 ! negatively regulates cardiac conduction relationship: RO:0002212 GO:0061337 ! negatively regulates cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: rph creation_date: 2015-01-07T13:20:20Z [Term] id: GO:1903781 name: positive regulation of cardiac conduction def: "Any process that activates or increases the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "activation of cardiac conduction" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac conduction" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061337 ! positively regulates cardiac conduction relationship: RO:0002213 GO:0061337 ! positively regulates cardiac conduction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: rph creation_date: 2015-01-07T13:20:28Z [Term] id: GO:1903782 name: regulation of sodium ion import across plasma membrane def: "Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:19376779] is_a: GO:1902305 ! regulation of sodium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098719 ! regulates sodium ion import across plasma membrane relationship: RO:0002211 GO:0098719 ! regulates sodium ion import across plasma membrane created_by: nc creation_date: 2015-01-07T16:48:43Z [Term] id: GO:1903783 name: negative regulation of sodium ion import across plasma membrane def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:19376779] synonym: "down regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "inhibition of sodium ion import across plasma membrane" NARROW [GOC:TermGenie] is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport is_a: GO:1903782 ! regulation of sodium ion import across plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098719 ! negatively regulates sodium ion import across plasma membrane relationship: RO:0002212 GO:0098719 ! negatively regulates sodium ion import across plasma membrane created_by: nc creation_date: 2015-01-07T16:48:51Z [Term] id: GO:1903784 name: positive regulation of sodium ion import across plasma membrane def: "Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:19376779] synonym: "activation of sodium ion import across plasma membrane" NARROW [GOC:TermGenie] synonym: "up regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport is_a: GO:1903782 ! regulation of sodium ion import across plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098719 ! positively regulates sodium ion import across plasma membrane relationship: RO:0002213 GO:0098719 ! positively regulates sodium ion import across plasma membrane created_by: nc creation_date: 2015-01-07T16:49:00Z [Term] id: GO:1903789 name: regulation of amino acid transmembrane transport def: "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:16115814] synonym: "regulation of amino acid membrane transport" EXACT [GOC:TermGenie] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003333 ! regulates amino acid transmembrane transport relationship: RO:0002211 GO:0003333 ! regulates amino acid transmembrane transport created_by: al creation_date: 2015-01-08T17:42:18Z [Term] id: GO:1903828 name: negative regulation of protein localization def: "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "inhibition of cellular protein localisation" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein localization" NARROW [GOC:TermGenie] synonym: "negative regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein localization" EXACT [] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008104 ! negatively regulates intracellular protein localization relationship: RO:0002212 GO:0008104 ! negatively regulates intracellular protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:24Z [Term] id: GO:1903829 name: positive regulation of protein localization def: "Any process that activates or increases the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "positive regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein localization" EXACT [] synonym: "up regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localization" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008104 ! positively regulates intracellular protein localization relationship: RO:0002213 GO:0008104 ! positively regulates intracellular protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:33Z [Term] id: GO:1903831 name: signal transduction involved in cellular response to ammonium ion def: "Any signal transduction that is involved in cellular response to ammonium ion." [GO_REF:0000060, GOC:TermGenie, PMID:16297994] synonym: "signaling cascade involved in cellular response to ammonium ion" NARROW [GOC:TermGenie] synonym: "signaling pathway involved in cellular response to ammonium ion" RELATED [GOC:TermGenie] synonym: "signalling cascade involved in cellular response to ammonium ion" NARROW [GOC:TermGenie] synonym: "signalling pathway involved in cellular response to ammonium ion" RELATED [GOC:TermGenie] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: part_of GO:0071242 ! cellular response to ammonium ion relationship: part_of GO:0071242 ! cellular response to ammonium ion created_by: al creation_date: 2015-01-21T17:52:09Z [Term] id: GO:1903847 name: regulation of aorta morphogenesis def: "Any process that modulates the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035909 ! regulates aorta morphogenesis relationship: RO:0002211 GO:0035909 ! regulates aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:00:51Z [Term] id: GO:1903848 name: negative regulation of aorta morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "down regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of aorta morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905652 ! negative regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035909 ! negatively regulates aorta morphogenesis relationship: RO:0002212 GO:0035909 ! negatively regulates aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:01:01Z [Term] id: GO:1903849 name: positive regulation of aorta morphogenesis def: "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "activation of aorta morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of aorta morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905653 ! positive regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035909 ! positively regulates aorta morphogenesis relationship: RO:0002213 GO:0035909 ! positively regulates aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:01:09Z [Term] id: GO:1903867 name: extraembryonic membrane development def: "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0073040584] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0005631 ! results in development of extraembryonic membrane relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0005631 ! results in development of extraembryonic membrane created_by: cjm creation_date: 2015-02-05T00:42:16Z [Term] id: GO:1903903 name: regulation of establishment of T cell polarity def: "Any process that modulates the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:2000114 ! regulation of establishment of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001768 ! regulates establishment of T cell polarity relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0001768 ! regulates establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:21Z [Term] id: GO:1903904 name: negative regulation of establishment of T cell polarity def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "down regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "inhibition of establishment of T cell polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T-cell polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "inhibition of T cell polarization" NARROW [GOC:TermGenie] synonym: "inhibition of T lymphocyte polarization" NARROW [GOC:TermGenie] synonym: "inhibition of T-cell polarization" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050868 ! negative regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001768 ! negatively regulates establishment of T cell polarity relationship: RO:0002212 GO:0001768 ! negatively regulates establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:30Z [Term] id: GO:1903905 name: positive regulation of establishment of T cell polarity def: "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "activation of establishment of T cell polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T-cell polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "activation of T cell polarization" NARROW [GOC:TermGenie] synonym: "activation of T lymphocyte polarization" NARROW [GOC:TermGenie] synonym: "activation of T-cell polarization" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050870 ! positive regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001768 ! positively regulates establishment of T cell polarity relationship: RO:0002213 GO:0001768 ! positively regulates establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:40Z [Term] id: GO:1903941 name: negative regulation of respiratory gaseous exchange def: "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "down regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "down-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "downregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "inhibition of respiratory gaseous exchange" NARROW [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007585 ! negatively regulates respiratory gaseous exchange by respiratory system relationship: RO:0002212 GO:0007585 ! negatively regulates respiratory gaseous exchange by respiratory system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-02-17T20:26:24Z [Term] id: GO:1903942 name: positive regulation of respiratory gaseous exchange def: "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "activation of respiratory gaseous exchange" NARROW [GOC:TermGenie] synonym: "up regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "up-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "upregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007585 ! positively regulates respiratory gaseous exchange by respiratory system relationship: RO:0002213 GO:0007585 ! positively regulates respiratory gaseous exchange by respiratory system property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-02-17T20:26:35Z [Term] id: GO:1903943 name: regulation of hepatocyte apoptotic process def: "Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097284 ! regulates hepatocyte apoptotic process relationship: RO:0002211 GO:0097284 ! regulates hepatocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-02-19T12:54:40Z [Term] id: GO:1903944 name: negative regulation of hepatocyte apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "down regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of hepatocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097284 ! negatively regulates hepatocyte apoptotic process relationship: RO:0002212 GO:0097284 ! negatively regulates hepatocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-02-19T12:54:50Z [Term] id: GO:1903945 name: positive regulation of hepatocyte apoptotic process def: "Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "activation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of hepatocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097284 ! positively regulates hepatocyte apoptotic process relationship: RO:0002213 GO:0097284 ! positively regulates hepatocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-02-19T12:54:59Z [Term] id: GO:1903950 name: negative regulation of AV node cell action potential def: "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "down regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "inhibition of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "inhibition of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "inhibition of AV node cell action potential" NARROW [GOC:TermGenie] synonym: "negative regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "negative regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0086016 ! negatively regulates AV node cell action potential relationship: RO:0002212 GO:0086016 ! negatively regulates AV node cell action potential property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: nc creation_date: 2015-02-20T14:59:41Z [Term] id: GO:1903951 name: positive regulation of AV node cell action potential def: "Any process that activates or increases the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "activation of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "activation of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "activation of AV node cell action potential" NARROW [GOC:TermGenie] synonym: "positive regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "positive regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0086016 ! positively regulates AV node cell action potential relationship: RO:0002213 GO:0086016 ! positively regulates AV node cell action potential property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4895 property_value: RO:0002161 NCBITaxon:4932 created_by: nc creation_date: 2015-02-20T14:59:50Z [Term] id: GO:1903975 name: regulation of glial cell migration def: "Any process that modulates the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008347 ! regulates glial cell migration relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0008347 ! regulates glial cell migration created_by: nc creation_date: 2015-03-02T15:13:31Z [Term] id: GO:1903976 name: negative regulation of glial cell migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "down regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of glia cell migration" NARROW [GOC:TermGenie] synonym: "inhibition of glial cell migration" NARROW [GOC:TermGenie] synonym: "negative regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008347 ! negatively regulates glial cell migration relationship: RO:0002212 GO:0008347 ! negatively regulates glial cell migration created_by: nc creation_date: 2015-03-02T15:13:38Z [Term] id: GO:1903977 name: positive regulation of glial cell migration def: "Any process that activates or increases the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "activation of glia cell migration" NARROW [GOC:TermGenie] synonym: "activation of glial cell migration" NARROW [GOC:TermGenie] synonym: "positive regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glial cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008347 ! positively regulates glial cell migration relationship: RO:0002213 GO:0008347 ! positively regulates glial cell migration created_by: nc creation_date: 2015-03-02T15:13:43Z [Term] id: GO:1904014 name: response to serotonin def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] is_a: GO:0071867 ! response to monoamine is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) relationship: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) created_by: sl creation_date: 2015-03-06T19:33:54Z [Term] id: GO:1904015 name: cellular response to serotonin def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] is_a: GO:0071868 ! cellular response to monoamine stimulus is_a: GO:1901701 ! cellular response to oxygen-containing compound is_a: GO:1904014 ! response to serotonin intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:350546 ! has primary input serotonin(1+) created_by: sl creation_date: 2015-03-06T19:34:00Z [Term] id: GO:1904018 name: positive regulation of vasculature development def: "Any process that activates or increases the frequency, rate or extent of vasculature development." [GO_REF:0000058, GOC:TermGenie, PMID:21472453] synonym: "activation of vascular system development" RELATED [GOC:TermGenie] synonym: "activation of vasculature development" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "upregulation of vascular system development" RELATED [GOC:TermGenie] synonym: "upregulation of vasculature development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001944 ! positively regulates vasculature development relationship: RO:0002213 GO:0001944 ! positively regulates vasculature development created_by: sl creation_date: 2015-03-06T22:17:04Z [Term] id: GO:1904019 name: epithelial cell apoptotic process def: "Any apoptotic process in an epithelial cell." [GO_REF:0000085, GOC:TermGenie, PMID:19137015] synonym: "epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000066 ! occurs in epithelial cell relationship: BFO:0000066 CL:0000066 ! occurs in epithelial cell property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-03-06T22:27:17Z [Term] id: GO:1904026 name: regulation of collagen fibril organization def: "Any process that modulates the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "regulation of collagen fibrillogenesis" RELATED [] synonym: "regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030199 ! regulates collagen fibril organization relationship: RO:0002211 GO:0030199 ! regulates collagen fibril organization property_value: RO:0002161 NCBITaxon:4751 created_by: ae creation_date: 2015-03-12T12:36:52Z [Term] id: GO:1904027 name: negative regulation of collagen fibril organization def: "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "down regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "downregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "inhibition of collagen fibril organisation" NARROW [GOC:TermGenie] synonym: "inhibition of collagen fibril organization" NARROW [GOC:TermGenie] synonym: "inhibition of fibrillar collagen organization" NARROW [GOC:TermGenie] synonym: "negative regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1903054 ! negative regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030199 ! negatively regulates collagen fibril organization relationship: RO:0002212 GO:0030199 ! negatively regulates collagen fibril organization property_value: RO:0002161 NCBITaxon:4751 created_by: ae creation_date: 2015-03-12T12:36:59Z [Term] id: GO:1904028 name: positive regulation of collagen fibril organization def: "Any process that activates or increases the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "activation of collagen fibril organisation" NARROW [GOC:TermGenie] synonym: "activation of collagen fibril organization" NARROW [GOC:TermGenie] synonym: "activation of fibrillar collagen organization" NARROW [GOC:TermGenie] synonym: "positive regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "upregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1903055 ! positive regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030199 ! positively regulates collagen fibril organization relationship: RO:0002213 GO:0030199 ! positively regulates collagen fibril organization property_value: RO:0002161 NCBITaxon:4751 created_by: ae creation_date: 2015-03-12T12:37:06Z [Term] id: GO:1904035 name: regulation of epithelial cell apoptotic process def: "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904019 ! regulates epithelial cell apoptotic process relationship: RO:0002211 GO:1904019 ! regulates epithelial cell apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-03-13T22:05:41Z [Term] id: GO:1904036 name: negative regulation of epithelial cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "down regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904019 ! negatively regulates epithelial cell apoptotic process relationship: RO:0002212 GO:1904019 ! negatively regulates epithelial cell apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-03-13T22:05:47Z [Term] id: GO:1904037 name: positive regulation of epithelial cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "activation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904019 ! positively regulates epithelial cell apoptotic process relationship: RO:0002213 GO:1904019 ! positively regulates epithelial cell apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-03-13T22:05:53Z [Term] id: GO:1904054 name: regulation of cholangiocyte proliferation def: "Any process that modulates the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990705 ! regulates cholangiocyte proliferation relationship: RO:0002211 GO:1990705 ! regulates cholangiocyte proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-03-18T17:56:14Z [Term] id: GO:1904055 name: negative regulation of cholangiocyte proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "down regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of cholangiocyte proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of hepatoblast proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990705 ! negatively regulates cholangiocyte proliferation relationship: RO:0002212 GO:1990705 ! negatively regulates cholangiocyte proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-03-18T17:56:20Z [Term] id: GO:1904056 name: positive regulation of cholangiocyte proliferation def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "activation of cholangiocyte proliferation" NARROW [GOC:TermGenie] synonym: "activation of hepatoblast proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990705 ! positively regulates cholangiocyte proliferation relationship: RO:0002213 GO:1990705 ! positively regulates cholangiocyte proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-03-18T17:56:26Z [Term] id: GO:1904057 name: negative regulation of sensory perception of pain def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "down regulation of nociception" EXACT [GOC:TermGenie] synonym: "down regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "down regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "down-regulation of nociception" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "down-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "downregulation of nociception" EXACT [GOC:TermGenie] synonym: "downregulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "downregulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "inhibition of nociception" NARROW [GOC:TermGenie] synonym: "inhibition of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "inhibition of sensory perception of pain" NARROW [GOC:TermGenie] synonym: "negative regulation of nociception" EXACT [GOC:TermGenie] synonym: "negative regulation of perception of physiological pain" NARROW [GOC:TermGenie] is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019233 ! negatively regulates sensory perception of pain relationship: RO:0002212 GO:0019233 ! negatively regulates sensory perception of pain created_by: sl creation_date: 2015-03-18T20:33:57Z [Term] id: GO:1904058 name: positive regulation of sensory perception of pain def: "Any process that activates or increases the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "activation of nociception" NARROW [GOC:TermGenie] synonym: "activation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "activation of sensory perception of pain" NARROW [GOC:TermGenie] synonym: "positive regulation of nociception" EXACT [GOC:TermGenie] synonym: "positive regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up regulation of nociception" EXACT [GOC:TermGenie] synonym: "up regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "up-regulation of nociception" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "upregulation of nociception" EXACT [GOC:TermGenie] synonym: "upregulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "upregulation of sensory perception of pain" EXACT [GOC:TermGenie] is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019233 ! positively regulates sensory perception of pain relationship: RO:0002213 GO:0019233 ! positively regulates sensory perception of pain created_by: sl creation_date: 2015-03-18T20:34:03Z [Term] id: GO:1904062 name: regulation of monoatomic cation transmembrane transport def: "Any process that modulates the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "regulation of cation transmembrane transport" BROAD [] is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098655 ! regulates monoatomic cation transmembrane transport relationship: RO:0002211 GO:0098655 ! regulates monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:43Z [Term] id: GO:1904063 name: negative regulation of cation transmembrane transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "down regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "inhibition of cation transmembrane transport" NARROW [GOC:TermGenie] is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098655 ! negatively regulates monoatomic cation transmembrane transport relationship: RO:0002212 GO:0098655 ! negatively regulates monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:50Z [Term] id: GO:1904064 name: positive regulation of cation transmembrane transport def: "Any process that activates or increases the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "activation of cation transmembrane transport" NARROW [GOC:TermGenie] synonym: "up regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of cation transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098655 ! positively regulates monoatomic cation transmembrane transport relationship: RO:0002213 GO:0098655 ! positively regulates monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:55Z [Term] id: GO:1904073 name: regulation of trophectodermal cell proliferation def: "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001834 ! regulates trophectodermal cell proliferation relationship: in_taxon NCBITaxon:32525 ! Theria relationship: RO:0002211 GO:0001834 ! regulates trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:55:56Z [Term] id: GO:1904074 name: negative regulation of trophectodermal cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "down regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of trophectoderm cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of trophectodermal cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001834 ! negatively regulates trophectodermal cell proliferation relationship: RO:0002212 GO:0001834 ! negatively regulates trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:56:02Z [Term] id: GO:1904075 name: positive regulation of trophectodermal cell proliferation def: "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "activation of trophectoderm cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of trophectodermal cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001834 ! positively regulates trophectodermal cell proliferation relationship: RO:0002213 GO:0001834 ! positively regulates trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:56:08Z [Term] id: GO:1904106 name: protein localization to microvillus def: "A process in which a protein is transported to, or maintained in, a location within a microvillus." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890] synonym: "protein localisation in microvillus" EXACT [GOC:TermGenie] synonym: "protein localisation to microvillus" EXACT [GOC:TermGenie] synonym: "protein localization in microvillus" EXACT [GOC:TermGenie] is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005902 ! has target end location microvillus relationship: RO:0002339 GO:0005902 ! has target end location microvillus created_by: kmv creation_date: 2015-04-01T18:14:41Z [Term] id: GO:1904115 name: axon cytoplasm def: "Any cytoplasm that is part of a axon." [GO_REF:0000064, GOC:TermGenie, PMID:18667152] synonym: "axoplasm" EXACT [] is_a: GO:0120111 ! neuron projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0030424 ! axon relationship: part_of GO:0030424 ! axon property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14472" xsd:anyURI created_by: sl creation_date: 2015-04-06T18:13:14Z [Term] id: GO:1904118 name: regulation of otic vesicle morphogenesis def: "Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071600 ! regulates otic vesicle morphogenesis relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002211 GO:0071600 ! regulates otic vesicle morphogenesis created_by: pga creation_date: 2015-04-07T14:00:56Z [Term] id: GO:1904119 name: negative regulation of otic vesicle morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] synonym: "down regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of otic vesicle morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0110111 ! negative regulation of animal organ morphogenesis is_a: GO:1904118 ! regulation of otic vesicle morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071600 ! negatively regulates otic vesicle morphogenesis relationship: RO:0002212 GO:0071600 ! negatively regulates otic vesicle morphogenesis created_by: pga creation_date: 2015-04-07T14:01:02Z [Term] id: GO:1904120 name: positive regulation of otic vesicle morphogenesis def: "Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] synonym: "activation of otic vesicle morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0110110 ! positive regulation of animal organ morphogenesis is_a: GO:1904118 ! regulation of otic vesicle morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071600 ! positively regulates otic vesicle morphogenesis relationship: RO:0002213 GO:0071600 ! positively regulates otic vesicle morphogenesis created_by: pga creation_date: 2015-04-07T14:01:08Z [Term] id: GO:1904145 name: negative regulation of meiotic cell cycle process involved in oocyte maturation def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "down regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "inhibition of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:1900194 ! negative regulation of oocyte maturation is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1903537 ! negatively regulates meiotic cell cycle process involved in oocyte maturation relationship: RO:0002212 GO:1903537 ! negatively regulates meiotic cell cycle process involved in oocyte maturation created_by: tb creation_date: 2015-04-14T15:59:22Z [Term] id: GO:1904146 name: positive regulation of meiotic cell cycle process involved in oocyte maturation def: "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "activation of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] synonym: "up regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1903537 ! positively regulates meiotic cell cycle process involved in oocyte maturation relationship: RO:0002213 GO:1903537 ! positively regulates meiotic cell cycle process involved in oocyte maturation created_by: tb creation_date: 2015-04-14T15:59:28Z [Term] id: GO:1904170 name: regulation of bleb assembly def: "Any process that modulates the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032060 ! regulates bleb assembly relationship: RO:0002211 GO:0032060 ! regulates bleb assembly created_by: als creation_date: 2015-04-23T09:32:19Z [Term] id: GO:1904171 name: negative regulation of bleb assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "down regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "down-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "downregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "inhibition of bleb assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cell blebbing" NARROW [GOC:TermGenie] synonym: "negative regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0032060 ! negatively regulates bleb assembly relationship: RO:0002212 GO:0032060 ! negatively regulates bleb assembly created_by: als creation_date: 2015-04-23T09:32:25Z [Term] id: GO:1904172 name: positive regulation of bleb assembly def: "Any process that activates or increases the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "activation of bleb assembly" NARROW [GOC:TermGenie] synonym: "activation of cell blebbing" NARROW [GOC:TermGenie] synonym: "positive regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "upregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0032060 ! positively regulates bleb assembly relationship: RO:0002213 GO:0032060 ! positively regulates bleb assembly created_by: als creation_date: 2015-04-23T09:32:31Z [Term] id: GO:1904177 name: regulation of adipose tissue development def: "Any process that modulates the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "regulation of adipogenesis" RELATED [GOC:TermGenie] xref: Reactome:R-HSA-9843745 "Adipogenesis" is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060612 ! regulates adipose tissue development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0060612 ! regulates adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:01Z [Term] id: GO:1904178 name: negative regulation of adipose tissue development def: "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "down regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "down regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of adipogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of adipose tissue development" NARROW [GOC:TermGenie] synonym: "negative regulation of adipogenesis" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060612 ! negatively regulates adipose tissue development relationship: RO:0002212 GO:0060612 ! negatively regulates adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:07Z [Term] id: GO:1904179 name: positive regulation of adipose tissue development def: "Any process that activates or increases the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "activation of adipogenesis" RELATED [GOC:TermGenie] synonym: "activation of adipose tissue development" NARROW [GOC:TermGenie] synonym: "positive regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of adipose tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060612 ! positively regulates adipose tissue development relationship: RO:0002213 GO:0060612 ! positively regulates adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:13Z [Term] id: GO:1904192 name: regulation of cholangiocyte apoptotic process def: "Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902488 ! regulates cholangiocyte apoptotic process relationship: RO:0002211 GO:1902488 ! regulates cholangiocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-05-06T15:25:48Z [Term] id: GO:1904193 name: negative regulation of cholangiocyte apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "down regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902488 ! negatively regulates cholangiocyte apoptotic process relationship: RO:0002212 GO:1902488 ! negatively regulates cholangiocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-05-06T15:25:55Z [Term] id: GO:1904194 name: positive regulation of cholangiocyte apoptotic process def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "activation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902488 ! positively regulates cholangiocyte apoptotic process relationship: RO:0002213 GO:1902488 ! positively regulates cholangiocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-05-06T15:26:00Z [Term] id: GO:1904204 name: regulation of skeletal muscle hypertrophy def: "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] is_a: GO:0014733 ! regulation of skeletal muscle adaptation is_a: GO:0014743 ! regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014734 ! regulates skeletal muscle hypertrophy relationship: RO:0002211 GO:0014734 ! regulates skeletal muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-05-08T17:38:13Z [Term] id: GO:1904205 name: negative regulation of skeletal muscle hypertrophy def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "down regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "inhibition of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014734 ! negatively regulates skeletal muscle hypertrophy relationship: RO:0002212 GO:0014734 ! negatively regulates skeletal muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-05-08T17:38:19Z [Term] id: GO:1904206 name: positive regulation of skeletal muscle hypertrophy def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "activation of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] synonym: "up regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014734 ! positively regulates skeletal muscle hypertrophy relationship: RO:0002213 GO:0014734 ! positively regulates skeletal muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-05-08T17:38:25Z [Term] id: GO:1904269 name: cell leading edge cell cortex def: "The cell cortex of the leading edge of a cell." [GO_REF:0000064, GOC:kmv, GOC:TermGenie, PMID:25843030] synonym: "cell cortex of cell leading edge" EXACT [GOC:TermGenie] synonym: "cell cortex of front of cell" EXACT [GOC:TermGenie] synonym: "cell cortex of leading edge of cell" EXACT [GOC:TermGenie] synonym: "cell periphery of cell leading edge" RELATED [GOC:TermGenie] synonym: "cell periphery of front of cell" RELATED [GOC:TermGenie] synonym: "cell periphery of leading edge of cell" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of cell leading edge" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of front of cell" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of leading edge of cell" RELATED [GOC:TermGenie] is_a: GO:0099738 ! cell cortex region intersection_of: GO:0099738 ! cell cortex region intersection_of: part_of GO:0031252 ! cell leading edge relationship: part_of GO:0031252 ! cell leading edge property_value: RO:0002161 NCBITaxon:4751 created_by: kmv creation_date: 2015-05-28T19:16:03Z [Term] id: GO:1904304 name: regulation of gastro-intestinal system smooth muscle contraction def: "Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] is_a: GO:0006940 ! regulation of smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014831 ! regulates gastro-intestinal system smooth muscle contraction relationship: RO:0002211 GO:0014831 ! regulates gastro-intestinal system smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-06-09T23:18:42Z [Term] id: GO:1904305 name: negative regulation of gastro-intestinal system smooth muscle contraction def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "down regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014831 ! negatively regulates gastro-intestinal system smooth muscle contraction relationship: RO:0002212 GO:0014831 ! negatively regulates gastro-intestinal system smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-06-09T23:18:48Z [Term] id: GO:1904306 name: positive regulation of gastro-intestinal system smooth muscle contraction def: "Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "activation of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014831 ! positively regulates gastro-intestinal system smooth muscle contraction relationship: RO:0002213 GO:0014831 ! positively regulates gastro-intestinal system smooth muscle contraction property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-06-09T23:18:54Z [Term] id: GO:1904318 name: regulation of smooth muscle contraction involved in micturition def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044062 ! regulation of excretion is_a: GO:0098801 ! regulation of renal system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060083 ! regulates smooth muscle contraction involved in micturition relationship: RO:0002211 GO:0060083 ! regulates smooth muscle contraction involved in micturition property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 property_value: RO:0002161 NCBITaxon:8782 created_by: sl creation_date: 2015-06-10T18:46:11Z [Term] id: GO:1904319 name: negative regulation of smooth muscle contraction involved in micturition def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "down regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "down regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "down regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "down-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "down-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "downregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "downregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "inhibition of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] synonym: "inhibition of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "inhibition of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "negative regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "negative regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060083 ! negatively regulates smooth muscle contraction involved in micturition relationship: RO:0002212 GO:0060083 ! negatively regulates smooth muscle contraction involved in micturition property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 property_value: RO:0002161 NCBITaxon:8782 created_by: sl creation_date: 2015-06-10T18:46:17Z [Term] id: GO:1904320 name: positive regulation of smooth muscle contraction involved in micturition def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "activation of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] synonym: "activation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "activation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "positive regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "positive regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "up regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "up regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "up regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "up-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "up-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "upregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "upregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060083 ! positively regulates smooth muscle contraction involved in micturition relationship: RO:0002213 GO:0060083 ! positively regulates smooth muscle contraction involved in micturition property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 property_value: RO:0002161 NCBITaxon:8782 created_by: sl creation_date: 2015-06-10T18:46:23Z [Term] id: GO:1904341 name: regulation of colon smooth muscle contraction def: "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990765 ! regulates colon smooth muscle contraction relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:1990765 ! regulates colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:16:58Z [Term] id: GO:1904342 name: negative regulation of colon smooth muscle contraction def: "Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "down regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of colon smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990765 ! negatively regulates colon smooth muscle contraction relationship: RO:0002212 GO:1990765 ! negatively regulates colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:17:05Z [Term] id: GO:1904343 name: positive regulation of colon smooth muscle contraction def: "Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "activation of colon smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990765 ! positively regulates colon smooth muscle contraction relationship: RO:0002213 GO:1990765 ! positively regulates colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:17:11Z [Term] id: GO:1904344 name: regulation of gastric mucosal blood circulation def: "Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990768 ! regulates gastric mucosal blood circulation relationship: RO:0002211 GO:1990768 ! regulates gastric mucosal blood circulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-06-11T21:20:31Z [Term] id: GO:1904345 name: negative regulation of gastric mucosal blood circulation def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "down regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "inhibition of gastric mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "inhibition of stomach mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "negative regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903523 ! negative regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990768 ! negatively regulates gastric mucosal blood circulation relationship: RO:0002212 GO:1990768 ! negatively regulates gastric mucosal blood circulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-06-11T21:20:44Z [Term] id: GO:1904346 name: positive regulation of gastric mucosal blood circulation def: "Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "activation of gastric mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "activation of stomach mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "positive regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903524 ! positive regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990768 ! positively regulates gastric mucosal blood circulation relationship: RO:0002213 GO:1990768 ! positively regulates gastric mucosal blood circulation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-06-11T21:20:50Z [Term] id: GO:1904347 name: regulation of small intestine smooth muscle contraction def: "Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990770 ! regulates small intestine smooth muscle contraction relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:1990770 ! regulates small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:34Z [Term] id: GO:1904348 name: negative regulation of small intestine smooth muscle contraction def: "Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "down regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990770 ! negatively regulates small intestine smooth muscle contraction relationship: RO:0002212 GO:1990770 ! negatively regulates small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:40Z [Term] id: GO:1904349 name: positive regulation of small intestine smooth muscle contraction def: "Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "activation of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990770 ! positively regulates small intestine smooth muscle contraction relationship: RO:0002213 GO:1990770 ! positively regulates small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:46Z [Term] id: GO:1904350 name: regulation of protein catabolic process in the vacuole def: "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0042176 ! regulation of protein catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007039 ! regulates protein catabolic process in the vacuole relationship: RO:0002211 GO:0007039 ! regulates protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:36Z [Term] id: GO:1904351 name: negative regulation of protein catabolic process in the vacuole def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "down regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "down regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "down-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "down-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "downregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "downregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "inhibition of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] synonym: "inhibition of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0042177 ! negative regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007039 ! negatively regulates protein catabolic process in the vacuole relationship: RO:0002212 GO:0007039 ! negatively regulates protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:42Z [Term] id: GO:1904352 name: positive regulation of protein catabolic process in the vacuole def: "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "activation of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] synonym: "activation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "up regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "up regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "up-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "up-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "upregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "upregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0045732 ! positive regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007039 ! positively regulates protein catabolic process in the vacuole relationship: RO:0002213 GO:0007039 ! positively regulates protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:49Z [Term] id: GO:1904375 name: regulation of protein localization to cell periphery def: "Any process that modulates the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990778 ! regulates protein localization to cell periphery relationship: RO:0002211 GO:1990778 ! regulates protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:25Z [Term] id: GO:1904376 name: negative regulation of protein localization to cell periphery def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "down regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "inhibition of protein localization to cell periphery" NARROW [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990778 ! negatively regulates protein localization to cell periphery relationship: RO:0002212 GO:1990778 ! negatively regulates protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:32Z [Term] id: GO:1904377 name: positive regulation of protein localization to cell periphery def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "activation of protein localization to cell periphery" NARROW [GOC:TermGenie] synonym: "up regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990778 ! positively regulates protein localization to cell periphery relationship: RO:0002213 GO:1990778 ! positively regulates protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:37Z [Term] id: GO:1904396 name: regulation of neuromuscular junction development def: "Any process that modulates the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "regulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007528 ! regulates neuromuscular junction development relationship: RO:0002211 GO:0007528 ! regulates neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:42Z [Term] id: GO:1904397 name: negative regulation of neuromuscular junction development def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "down regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "down regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "down regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "down-regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "downregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "downregulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "inhibition of neuromuscular junction development" NARROW [GOC:TermGenie] synonym: "inhibition of neuromuscular junction organization" NARROW [GOC:TermGenie] synonym: "inhibition of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "inhibition of NMJ stability" RELATED [GOC:TermGenie] synonym: "negative regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "negative regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "negative regulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:1904396 ! regulation of neuromuscular junction development is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007528 ! negatively regulates neuromuscular junction development relationship: RO:0002212 GO:0007528 ! negatively regulates neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:48Z [Term] id: GO:1904398 name: positive regulation of neuromuscular junction development def: "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "activation of neuromuscular junction development" NARROW [GOC:TermGenie] synonym: "activation of neuromuscular junction organization" NARROW [GOC:TermGenie] synonym: "activation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "activation of NMJ stability" RELATED [GOC:TermGenie] synonym: "positive regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "positive regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "positive regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "up regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "up regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "up-regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "upregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "upregulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1904396 ! regulation of neuromuscular junction development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007528 ! positively regulates neuromuscular junction development relationship: RO:0002213 GO:0007528 ! positively regulates neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:54Z [Term] id: GO:1904409 name: regulation of secretory granule organization def: "Any process that modulates the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033363 ! regulates secretory granule organization relationship: RO:0002211 GO:0033363 ! regulates secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:42Z [Term] id: GO:1904410 name: negative regulation of secretory granule organization def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "down regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "down regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of secretory granule organisation" NARROW [GOC:TermGenie] synonym: "inhibition of secretory granule organization" NARROW [GOC:TermGenie] synonym: "inhibition of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033363 ! negatively regulates secretory granule organization relationship: RO:0002212 GO:0033363 ! negatively regulates secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:49Z [Term] id: GO:1904411 name: positive regulation of secretory granule organization def: "Any process that activates or increases the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "activation of secretory granule organisation" NARROW [GOC:TermGenie] synonym: "activation of secretory granule organization" NARROW [GOC:TermGenie] synonym: "activation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033363 ! positively regulates secretory granule organization relationship: RO:0002213 GO:0033363 ! positively regulates secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:55Z [Term] id: GO:1904412 name: regulation of cardiac ventricle development def: "Any process that modulates the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003231 ! regulates cardiac ventricle development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003231 ! regulates cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:15Z [Term] id: GO:1904413 name: negative regulation of cardiac ventricle development def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "down regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac ventricle development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003231 ! negatively regulates cardiac ventricle development relationship: RO:0002212 GO:0003231 ! negatively regulates cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:21Z [Term] id: GO:1904414 name: positive regulation of cardiac ventricle development def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "activation of cardiac ventricle development" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003231 ! positively regulates cardiac ventricle development relationship: RO:0002213 GO:0003231 ! positively regulates cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:27Z [Term] id: GO:1904456 name: negative regulation of neuronal action potential def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "down regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "down regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "down-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "downregulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "downregulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "inhibition of generation of action potential" RELATED [GOC:TermGenie] synonym: "inhibition of neuronal action potential" NARROW [GOC:TermGenie] synonym: "negative regulation of generation of action potential" RELATED [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0051970 ! negative regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0019228 ! negatively regulates neuronal action potential relationship: RO:0002212 GO:0019228 ! negatively regulates neuronal action potential created_by: sl creation_date: 2015-07-09T18:02:40Z [Term] id: GO:1904457 name: positive regulation of neuronal action potential def: "Any process that activates or increases the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "activation of generation of action potential" RELATED [GOC:TermGenie] synonym: "activation of neuronal action potential" NARROW [GOC:TermGenie] synonym: "positive regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "upregulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "upregulation of neuronal action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0051971 ! positive regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0019228 ! positively regulates neuronal action potential relationship: RO:0002213 GO:0019228 ! positively regulates neuronal action potential created_by: sl creation_date: 2015-07-09T18:02:46Z [Term] id: GO:1904484 name: cloacal gland development def: "The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:mr, GOC:TermGenie, PMID:18805421] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0012478 ! results in development of cloacal gland relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0012478 ! results in development of cloacal gland created_by: mr creation_date: 2015-07-15T22:14:39Z [Term] id: GO:1904491 name: protein localization to ciliary transition zone def: "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:21422230] synonym: "protein localisation in ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary transition zone" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0035869 ! has target end location ciliary transition zone relationship: RO:0002339 GO:0035869 ! has target end location ciliary transition zone property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: kmv creation_date: 2015-07-17T20:43:21Z [Term] id: GO:1904587 name: response to glycoprotein def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] synonym: "response to glycoproteins" EXACT [] is_a: GO:1901698 ! response to nitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein relationship: RO:0004009 CHEBI:17089 ! has primary input glycoprotein created_by: sl creation_date: 2015-08-20T16:46:24Z [Term] id: GO:1904588 name: cellular response to glycoprotein def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] synonym: "cellular response to glycoproteins" EXACT [] is_a: GO:1901699 ! cellular response to nitrogen compound is_a: GO:1901701 ! cellular response to oxygen-containing compound is_a: GO:1904587 ! response to glycoprotein intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:17089 ! has primary input glycoprotein created_by: sl creation_date: 2015-08-20T16:46:30Z [Term] id: GO:1904606 name: fat cell apoptotic process def: "Any apoptotic process in a fat cell." [GO_REF:0000085, GOC:TermGenie, PMID:17024416] synonym: "adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000136 ! occurs in adipocyte relationship: BFO:0000066 CL:0000136 ! occurs in adipocyte property_value: RO:0002161 NCBITaxon:4896 created_by: sl creation_date: 2015-08-27T18:13:06Z [Term] id: GO:1904649 name: regulation of fat cell apoptotic process def: "Any process that modulates the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904606 ! regulates fat cell apoptotic process relationship: RO:0002211 GO:1904606 ! regulates fat cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: sl creation_date: 2015-08-31T20:59:28Z [Term] id: GO:1904650 name: negative regulation of fat cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "down regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of adipocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of adipose cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of fat cell apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904606 ! negatively regulates fat cell apoptotic process relationship: RO:0002212 GO:1904606 ! negatively regulates fat cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: sl creation_date: 2015-08-31T20:59:34Z [Term] id: GO:1904651 name: positive regulation of fat cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "activation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of adipocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of adipose cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of fat cell apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904606 ! positively regulates fat cell apoptotic process relationship: RO:0002213 GO:1904606 ! positively regulates fat cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: sl creation_date: 2015-08-31T20:59:40Z [Term] id: GO:1904659 name: D-glucose transmembrane transport alt_id: GO:0015758 def: "The process in which D-glucose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:9090050] synonym: "glucose transmembrane transport" EXACT [] synonym: "glucose transport" RELATED [] is_a: GO:0008645 ! hexose transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose relationship: RO:0004009 CHEBI:4167 ! has primary input D-glucopyranose created_by: vw creation_date: 2015-09-04T17:20:16Z [Term] id: GO:1904671 name: negative regulation of cell differentiation involved in stem cell population maintenance def: "Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down-regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "downregulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "inhibition of cell differentiation involved in stem cell population maintenance" NARROW [GOC:TermGenie] synonym: "negative regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0045596 ! negative regulation of cell differentiation intersection_of: part_of GO:0019827 ! stem cell population maintenance relationship: part_of GO:0019827 ! stem cell population maintenance property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2015-09-12T00:46:08Z [Term] id: GO:1904672 name: regulation of somatic stem cell population maintenance def: "Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035019 ! regulates somatic stem cell population maintenance relationship: RO:0002211 GO:0035019 ! regulates somatic stem cell population maintenance property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: rph creation_date: 2015-09-14T08:40:19Z [Term] id: GO:1904673 name: negative regulation of somatic stem cell population maintenance def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of somatic stem cell population maintenance" NARROW [GOC:TermGenie] is_a: GO:1902455 ! negative regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035019 ! negatively regulates somatic stem cell population maintenance relationship: RO:0002212 GO:0035019 ! negatively regulates somatic stem cell population maintenance property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: rph creation_date: 2015-09-14T08:40:25Z [Term] id: GO:1904674 name: positive regulation of somatic stem cell population maintenance def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "activation of somatic stem cell population maintenance" NARROW [GOC:TermGenie] synonym: "up regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] is_a: GO:1902459 ! positive regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035019 ! positively regulates somatic stem cell population maintenance relationship: RO:0002213 GO:0035019 ! positively regulates somatic stem cell population maintenance property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: rph creation_date: 2015-09-14T08:40:32Z [Term] id: GO:1904675 name: regulation of somatic stem cell division def: "Any process that modulates the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:2000035 ! regulation of stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048103 ! regulates somatic stem cell division relationship: RO:0002211 GO:0048103 ! regulates somatic stem cell division property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: rph creation_date: 2015-09-14T08:47:22Z [Term] id: GO:1904676 name: negative regulation of somatic stem cell division def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "inhibition of somatic stem cell division" NARROW [GOC:TermGenie] synonym: "inhibition of somatic stem cell renewal" NARROW [GOC:TermGenie] synonym: "negative regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051782 ! negative regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048103 ! negatively regulates somatic stem cell division relationship: RO:0002212 GO:0048103 ! negatively regulates somatic stem cell division property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: rph creation_date: 2015-09-14T08:47:28Z [Term] id: GO:1904677 name: positive regulation of somatic stem cell division def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "activation of somatic stem cell division" NARROW [GOC:TermGenie] synonym: "activation of somatic stem cell renewal" NARROW [GOC:TermGenie] synonym: "positive regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051781 ! positive regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048103 ! positively regulates somatic stem cell division relationship: RO:0002213 GO:0048103 ! positively regulates somatic stem cell division property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: rph creation_date: 2015-09-14T08:47:34Z [Term] id: GO:1904680 name: peptide transmembrane transporter activity alt_id: GO:0015197 alt_id: GO:0015637 def: "Enables the transfer of a peptide from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, GOC:vw] synonym: "peptide transporter activity" RELATED [] synonym: "peptide uptake permease activity" RELATED [] xref: Reactome:R-HSA-1500817 "Glutathione is taken up by the bacterium" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: RO:0002342 GO:0016020 ! results in transport across membrane intersection_of: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion relationship: RO:0004009 CHEBI:60466 ! has primary input peptide zwitterion created_by: tb creation_date: 2015-09-22T18:50:41Z [Term] id: GO:1904688 name: regulation of cytoplasmic translational initiation def: "Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation." [GO_REF:0000058, GOC:TermGenie, PMID:12242291] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:2000765 ! regulation of cytoplasmic translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002183 ! regulates cytoplasmic translational initiation relationship: RO:0002211 GO:0002183 ! regulates cytoplasmic translational initiation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21560" xsd:anyURI created_by: dos creation_date: 2015-09-25T14:39:38Z [Term] id: GO:1904689 name: negative regulation of cytoplasmic translational initiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation." [GO_REF:0000058, GOC:TermGenie, PMID:12242291] synonym: "down regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] synonym: "downregulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] synonym: "inhibition of cytoplasmic translational initiation" NARROW [GOC:TermGenie] is_a: GO:0045947 ! negative regulation of translational initiation is_a: GO:1904688 ! regulation of cytoplasmic translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002183 ! negatively regulates cytoplasmic translational initiation relationship: RO:0002212 GO:0002183 ! negatively regulates cytoplasmic translational initiation created_by: dos creation_date: 2015-09-25T14:39:44Z [Term] id: GO:1904690 name: positive regulation of cytoplasmic translational initiation def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation." [GO_REF:0000058, GOC:TermGenie, PMID:12242291] synonym: "activation of cytoplasmic translational initiation" NARROW [GOC:TermGenie] synonym: "up regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] synonym: "upregulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] is_a: GO:0045948 ! positive regulation of translational initiation is_a: GO:1904688 ! regulation of cytoplasmic translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002183 ! positively regulates cytoplasmic translational initiation relationship: RO:0002213 GO:0002183 ! positively regulates cytoplasmic translational initiation created_by: dos creation_date: 2015-09-25T14:39:50Z [Term] id: GO:1904691 name: negative regulation of type B pancreatic cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "down regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of pancreatic B cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044342 ! negatively regulates type B pancreatic cell proliferation relationship: RO:0002212 GO:0044342 ! negatively regulates type B pancreatic cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-09-25T15:23:38Z [Term] id: GO:1904692 name: positive regulation of type B pancreatic cell proliferation def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "activation of pancreatic B cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044342 ! positively regulates type B pancreatic cell proliferation relationship: RO:0002213 GO:0044342 ! positively regulates type B pancreatic cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-09-25T15:23:44Z [Term] id: GO:1904693 name: midbrain morphogenesis def: "The developmental process by which a midbrain is generated and organized." [GO_REF:0000083, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250] synonym: "MB morphogenesis" BROAD [GOC:TermGenie] synonym: "mesencephalon morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0001891 ! results in morphogenesis of midbrain relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030901 ! midbrain development relationship: part_of GO:0048854 ! brain morphogenesis relationship: RO:0002298 UBERON:0001891 ! results in morphogenesis of midbrain created_by: bf creation_date: 2015-09-29T09:15:28Z [Term] id: GO:1904697 name: regulation of acinar cell proliferation def: "Any process that modulates the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990863 ! regulates acinar cell proliferation relationship: RO:0002211 GO:1990863 ! regulates acinar cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-09-30T15:19:50Z [Term] id: GO:1904698 name: negative regulation of acinar cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "down regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of acinar cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of acinic cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of acinous cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990863 ! negatively regulates acinar cell proliferation relationship: RO:0002212 GO:1990863 ! negatively regulates acinar cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-09-30T15:19:57Z [Term] id: GO:1904699 name: positive regulation of acinar cell proliferation def: "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "activation of acinar cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of acinic cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of acinous cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990863 ! positively regulates acinar cell proliferation relationship: RO:0002213 GO:1990863 ! positively regulates acinar cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-09-30T15:20:03Z [Term] id: GO:1904705 name: regulation of vascular associated smooth muscle cell proliferation def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1990874 ! regulates vascular associated smooth muscle cell proliferation relationship: RO:0002211 GO:1990874 ! regulates vascular associated smooth muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-10-01T16:05:20Z [Term] id: GO:1904706 name: negative regulation of vascular associated smooth muscle cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "down regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "negative regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048662 ! negative regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1990874 ! negatively regulates vascular associated smooth muscle cell proliferation relationship: RO:0002212 GO:1990874 ! negatively regulates vascular associated smooth muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-10-01T16:05:26Z [Term] id: GO:1904707 name: positive regulation of vascular associated smooth muscle cell proliferation def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "activation of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of VSMC proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "positive regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048661 ! positive regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1990874 ! positively regulates vascular associated smooth muscle cell proliferation relationship: RO:0002213 GO:1990874 ! positively regulates vascular associated smooth muscle cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-10-01T16:05:32Z [Term] id: GO:1904738 name: vascular associated smooth muscle cell migration def: "The orderly movement of a vascular associated smooth muscle cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "vascular smooth muscle cell migration" EXACT [] is_a: GO:0014909 ! smooth muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000359 ! results in movement of vascular associated smooth muscle cell relationship: RO:0002565 CL:0000359 ! results in movement of vascular associated smooth muscle cell property_value: RO:0002161 NCBITaxon:4890 created_by: rph creation_date: 2015-10-15T09:56:00Z [Term] id: GO:1904746 name: negative regulation of apoptotic process involved in development def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: U4PR86 in PMID:22801495 inferred from mutant phenotype synonym: "down regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902742 ! negatively regulates apoptotic process involved in development relationship: RO:0002212 GO:1902742 ! negatively regulates apoptotic process involved in development property_value: RO:0002161 NCBITaxon:4896 created_by: es creation_date: 2015-10-19T14:12:27Z [Term] id: GO:1904747 name: positive regulation of apoptotic process involved in development def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: U4PR86 in PMID:22801495 inferred from mutant phenotype synonym: "activation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902742 ! positively regulates apoptotic process involved in development relationship: RO:0002213 GO:1902742 ! positively regulates apoptotic process involved in development property_value: RO:0002161 NCBITaxon:4896 created_by: es creation_date: 2015-10-19T14:12:34Z [Term] id: GO:1904748 name: regulation of apoptotic process involved in development def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: Q10943 in PMID:22801495, inferred from mutant phenotype synonym: "regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902742 ! regulates apoptotic process involved in development relationship: RO:0002211 GO:1902742 ! regulates apoptotic process involved in development property_value: RO:0002161 NCBITaxon:4896 created_by: es creation_date: 2015-10-19T15:02:28Z [Term] id: GO:1904749 name: regulation of protein localization to nucleolus def: "Any process that modulates the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902570 ! regulates protein localization to nucleolus relationship: RO:0002211 GO:1902570 ! regulates protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:17Z [Term] id: GO:1904750 name: negative regulation of protein localization to nucleolus def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "down regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to nucleolus" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900181 ! negative regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902570 ! negatively regulates protein localization to nucleolus relationship: RO:0002212 GO:1902570 ! negatively regulates protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:24Z [Term] id: GO:1904751 name: positive regulation of protein localization to nucleolus def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "activation of protein localisation in nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localization to nucleolus" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900182 ! positive regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902570 ! positively regulates protein localization to nucleolus relationship: RO:0002213 GO:1902570 ! positively regulates protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:30Z [Term] id: GO:1904752 name: regulation of vascular associated smooth muscle cell migration def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014910 ! regulation of smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1904738 ! regulates vascular associated smooth muscle cell migration relationship: RO:0002211 GO:1904738 ! regulates vascular associated smooth muscle cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: rph creation_date: 2015-10-19T15:49:52Z [Term] id: GO:1904753 name: negative regulation of vascular associated smooth muscle cell migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "down regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014912 ! negative regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1904738 ! negatively regulates vascular associated smooth muscle cell migration relationship: RO:0002212 GO:1904738 ! negatively regulates vascular associated smooth muscle cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: rph creation_date: 2015-10-19T15:49:58Z [Term] id: GO:1904754 name: positive regulation of vascular associated smooth muscle cell migration def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "activation of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014911 ! positive regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1904738 ! positively regulates vascular associated smooth muscle cell migration relationship: RO:0002213 GO:1904738 ! positively regulates vascular associated smooth muscle cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: rph creation_date: 2015-10-19T15:50:05Z [Term] id: GO:1904770 name: intramembranous bone morphogenesis def: "The developmental process by which an intramembranous bone is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:26399686] synonym: "intramembranous bones morphogenesis" RELATED [GOC:TermGenie] synonym: "membrane bone morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002514 ! results in morphogenesis of intramembranous bone relationship: RO:0002298 UBERON:0002514 ! results in morphogenesis of intramembranous bone created_by: dos creation_date: 2015-10-28T11:46:04Z [Term] id: GO:1904776 name: regulation of protein localization to cell cortex def: "Any process that modulates the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072697 ! regulates protein localization to cell cortex relationship: RO:0002211 GO:0072697 ! regulates protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:01Z [Term] id: GO:1904777 name: negative regulation of protein localization to cell cortex def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "down regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to cell cortex" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to cell cortex" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072697 ! negatively regulates protein localization to cell cortex relationship: RO:0002212 GO:0072697 ! negatively regulates protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:08Z [Term] id: GO:1904778 name: positive regulation of protein localization to cell cortex def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "activation of protein localisation to cell cortex" NARROW [GOC:TermGenie] synonym: "activation of protein localization to cell cortex" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072697 ! positively regulates protein localization to cell cortex relationship: RO:0002213 GO:0072697 ! positively regulates protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:15Z [Term] id: GO:1904809 name: regulation of dense core granule transport def: "Any process that modulates the frequency, rate or extent of dense core granule transport." [GO_REF:0000058, GOC:TermGenie, PMID:22699897] comment: cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype). synonym: "regulation of dense core vesicle transport" EXACT [GOC:TermGenie] is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1901950 ! regulates dense core granule transport relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:1901950 ! regulates dense core granule transport created_by: es creation_date: 2015-11-11T10:40:10Z [Term] id: GO:1904810 name: negative regulation of dense core granule transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport." [GO_REF:0000058, GOC:TermGenie, PMID:22699897] comment: cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype). synonym: "down regulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "down regulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "down-regulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "down-regulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "downregulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "downregulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "inhibition of dense core granule transport" NARROW [GOC:TermGenie] synonym: "inhibition of dense core vesicle transport" NARROW [GOC:TermGenie] synonym: "negative regulation of dense core vesicle transport" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1904809 ! regulation of dense core granule transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1901950 ! negatively regulates dense core granule transport relationship: RO:0002212 GO:1901950 ! negatively regulates dense core granule transport created_by: es creation_date: 2015-11-11T10:40:18Z [Term] id: GO:1904811 name: positive regulation of dense core granule transport def: "Any process that activates or increases the frequency, rate or extent of dense core granule transport." [GO_REF:0000058, GOC:TermGenie, PMID:22699897] comment: cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype). synonym: "activation of dense core granule transport" NARROW [GOC:TermGenie] synonym: "activation of dense core vesicle transport" NARROW [GOC:TermGenie] synonym: "positive regulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "up regulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "up regulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "up-regulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "up-regulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "upregulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "upregulation of dense core vesicle transport" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1904809 ! regulation of dense core granule transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1901950 ! positively regulates dense core granule transport relationship: RO:0002213 GO:1901950 ! positively regulates dense core granule transport created_by: es creation_date: 2015-11-11T10:40:25Z [Term] id: GO:1904817 name: serous membrane development def: "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "serosa development" RELATED [GOC:TermGenie] synonym: "tunica serosa development" EXACT [GOC:TermGenie] synonym: "wall of serous sac development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0000042 ! results in development of serous membrane relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002296 UBERON:0000042 ! results in development of serous membrane created_by: dph creation_date: 2015-11-17T19:00:01Z [Term] id: GO:1904818 name: visceral peritoneum development def: "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001178 ! results in development of visceral peritoneum relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:1904820 ! peritoneum development relationship: RO:0002296 UBERON:0001178 ! results in development of visceral peritoneum created_by: dph creation_date: 2015-11-17T19:00:17Z [Term] id: GO:1904819 name: parietal peritoneum development def: "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "peritoneal cavity lining development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001366 ! results in development of parietal peritoneum relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:1904820 ! peritoneum development relationship: RO:0002296 UBERON:0001366 ! results in development of parietal peritoneum created_by: dph creation_date: 2015-11-17T19:00:24Z [Term] id: GO:1904820 name: peritoneum development def: "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "peritonaeum development" RELATED [GOC:TermGenie] is_a: GO:1904817 ! serous membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0002358 ! results in development of peritoneum relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002296 UBERON:0002358 ! results in development of peritoneum created_by: dph creation_date: 2015-11-18T17:23:51Z [Term] id: GO:1904829 name: regulation of aortic smooth muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035887 ! regulates aortic smooth muscle cell differentiation relationship: RO:0002211 GO:0035887 ! regulates aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:40Z [Term] id: GO:1904830 name: negative regulation of aortic smooth muscle cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "down regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905064 ! negative regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035887 ! negatively regulates aortic smooth muscle cell differentiation relationship: RO:0002212 GO:0035887 ! negatively regulates aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:47Z [Term] id: GO:1904831 name: positive regulation of aortic smooth muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "activation of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905065 ! positive regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035887 ! positively regulates aortic smooth muscle cell differentiation relationship: RO:0002213 GO:0035887 ! positively regulates aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:54Z [Term] id: GO:1904836 name: facioacoustic ganglion morphogenesis def: "The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized." [GO_REF:0000083, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] synonym: "acoustico-facial VII-VIII ganglion complex morphogenesis" EXACT [UBERON:0012175] synonym: "acousticofacial ganglion morphogenesis" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion complex morphogenesis" RELATED [GOC:TermGenie] synonym: "facio-acoustic ganglion complex VII-VIII morphogenesis" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion morphogenesis" EXACT [GOC:TermGenie] synonym: "facio-acoustic VII-VIII ganglion complex morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0061559 ! cranial ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0012175 ! results in morphogenesis of acoustico-facial VII-VIII ganglion complex relationship: part_of GO:1903375 ! facioacoustic ganglion development relationship: RO:0002298 UBERON:0012175 ! results in morphogenesis of acoustico-facial VII-VIII ganglion complex created_by: bf creation_date: 2015-12-01T17:02:06Z [Term] id: GO:1904888 name: cranial skeletal system development def: "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000094, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11262227] synonym: "cranial skeleton development" NARROW [GOC:TermGenie] synonym: "craniofacial development" NARROW [PMID:11262227] synonym: "cranium development" RELATED [GOC:TermGenie] synonym: "osteocranium development" NARROW [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0010323 ! results in development of cranial skeletal system relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002296 UBERON:0010323 ! results in development of cranial skeletal system created_by: bf creation_date: 2016-01-07T13:45:06Z [Term] id: GO:1904933 name: regulation of cell proliferation in midbrain def: "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0033278 ! regulates cell proliferation in midbrain relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002211 GO:0033278 ! regulates cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:11Z [Term] id: GO:1904934 name: negative regulation of cell proliferation in midbrain def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "down regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "down regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "down-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "down-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "downregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "downregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "inhibition of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] synonym: "inhibition of cell proliferation in midbrain" NARROW [GOC:TermGenie] synonym: "inhibition of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "negative regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "negative regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0033278 ! negatively regulates cell proliferation in midbrain relationship: RO:0002212 GO:0033278 ! negatively regulates cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:19Z [Term] id: GO:1904935 name: positive regulation of cell proliferation in midbrain def: "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302] synonym: "activation of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] synonym: "activation of cell proliferation in midbrain" NARROW [GOC:TermGenie] synonym: "activation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "positive regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "positive regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "up regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "up regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "up-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "up-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "upregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "upregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0033278 ! positively regulates cell proliferation in midbrain relationship: RO:0002213 GO:0033278 ! positively regulates cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:27Z [Term] id: GO:1904936 name: interneuron migration def: "The orderly movement of an interneuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] synonym: "inter neuron migration" EXACT [GOC:ah] synonym: "inter-neuron migration" EXACT [GOC:ah] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000099 ! results in movement of interneuron relationship: RO:0002565 CL:0000099 ! results in movement of interneuron created_by: ah creation_date: 2016-02-01T14:04:32Z [Term] id: GO:1904937 name: sensory neuron migration def: "The orderly movement of a sensory neuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000101 ! results in movement of sensory neuron relationship: RO:0002565 CL:0000101 ! results in movement of sensory neuron created_by: ah creation_date: 2016-02-01T14:15:50Z [Term] id: GO:1904942 name: regulation of cardiac ventricle formation def: "Any process that modulates the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003211 ! regulates cardiac ventricle formation relationship: RO:0002211 GO:0003211 ! regulates cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:16Z [Term] id: GO:1904943 name: negative regulation of cardiac ventricle formation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "down regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac ventricle formation" NARROW [GOC:TermGenie] is_a: GO:1901211 ! negative regulation of cardiac chamber formation is_a: GO:1904413 ! negative regulation of cardiac ventricle development is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003211 ! negatively regulates cardiac ventricle formation relationship: RO:0002212 GO:0003211 ! negatively regulates cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:24Z [Term] id: GO:1904944 name: positive regulation of cardiac ventricle formation def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "activation of cardiac ventricle formation" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] is_a: GO:1901212 ! positive regulation of cardiac chamber formation is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003211 ! positively regulates cardiac ventricle formation relationship: RO:0002213 GO:0003211 ! positively regulates cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:31Z [Term] id: GO:1904950 name: negative regulation of establishment of protein localization def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "down regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "downregulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "inhibition of establishment of protein localisation" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of protein localization" NARROW [GOC:TermGenie] synonym: "inhibition of protein positioning" NARROW [GOC:TermGenie] synonym: "inhibition of protein recruitment" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045184 ! negatively regulates establishment of protein localization relationship: RO:0002212 GO:0045184 ! negatively regulates establishment of protein localization created_by: mec creation_date: 2016-02-05T09:59:24Z [Term] id: GO:1904951 name: positive regulation of establishment of protein localization def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "activation of establishment of protein localisation" NARROW [GOC:TermGenie] synonym: "activation of establishment of protein localization" NARROW [GOC:TermGenie] synonym: "activation of protein positioning" NARROW [GOC:TermGenie] synonym: "activation of protein recruitment" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "upregulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0045184 ! positively regulates establishment of protein localization relationship: RO:0002213 GO:0045184 ! positively regulates establishment of protein localization created_by: mec creation_date: 2016-02-05T09:59:32Z [Term] id: GO:1904987 name: regulation of endothelial cell activation def: "Any process that modulates the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042118 ! regulates endothelial cell activation relationship: RO:0002211 GO:0042118 ! regulates endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:09Z [Term] id: GO:1904988 name: negative regulation of endothelial cell activation def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "down regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial cell activation" NARROW [GOC:TermGenie] is_a: GO:0050866 ! negative regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042118 ! negatively regulates endothelial cell activation relationship: RO:0002212 GO:0042118 ! negatively regulates endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:18Z [Term] id: GO:1904989 name: positive regulation of endothelial cell activation def: "Any process that activates or increases the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "activation of endothelial cell activation" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell activation" EXACT [GOC:TermGenie] is_a: GO:0050867 ! positive regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042118 ! positively regulates endothelial cell activation relationship: RO:0002213 GO:0042118 ! positively regulates endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:25Z [Term] id: GO:1905038 name: regulation of membrane lipid metabolic process def: "Any process that modulates the frequency, rate or extent of membrane lipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:25954280] synonym: "regulation of membrane lipid metabolism" EXACT [GOC:TermGenie] is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006643 ! regulates membrane lipid metabolic process relationship: RO:0002211 GO:0006643 ! regulates membrane lipid metabolic process created_by: tb creation_date: 2016-03-08T20:41:32Z [Term] id: GO:1905039 name: carboxylic acid transmembrane transport def: "The process in which carboxylic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:10869563] is_a: GO:0046942 ! carboxylic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: RO:0004009 CHEBI:29067 ! has primary input carboxylic acid anion created_by: vw creation_date: 2016-03-09T15:33:53Z [Term] id: GO:1905040 name: otic placode development def: "The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure." [GO_REF:0000094, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] synonym: "auditory placode development" RELATED [GOC:TermGenie] synonym: "ear placode development" RELATED [GOC:TermGenie] synonym: "ear/otic placode development" RELATED [GOC:TermGenie] synonym: "octaval placode development" RELATED [GOC:TermGenie] synonym: "octaval VIII placode development" RELATED [GOC:TermGenie] synonym: "placoda otica development" EXACT [GOC:TermGenie] is_a: GO:0071696 ! ectodermal placode development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0003069 ! results in development of otic placode relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002296 UBERON:0003069 ! results in development of otic placode created_by: bf creation_date: 2016-03-10T09:30:20Z [Term] id: GO:1905063 name: regulation of vascular associated smooth muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035886 ! regulates vascular associated smooth muscle cell differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0035886 ! regulates vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:14:53Z [Term] id: GO:1905064 name: negative regulation of vascular associated smooth muscle cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "down regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035886 ! negatively regulates vascular associated smooth muscle cell differentiation relationship: RO:0002212 GO:0035886 ! negatively regulates vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:15:03Z [Term] id: GO:1905065 name: positive regulation of vascular associated smooth muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "activation of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of VSMC differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035886 ! positively regulates vascular associated smooth muscle cell differentiation relationship: RO:0002213 GO:0035886 ! positively regulates vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:15:13Z [Term] id: GO:1905069 name: allantois development def: "The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:17440924, PMID:21470579] synonym: "allantoic bud development" RELATED [GOC:TermGenie] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0004340 ! results in development of allantois relationship: in_taxon NCBITaxon:32524 ! Amniota relationship: RO:0002296 UBERON:0004340 ! results in development of allantois created_by: cls creation_date: 2016-03-21T15:18:21Z [Term] id: GO:1905126 name: regulation of axo-dendritic protein transport def: "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "regulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099640 ! regulates axo-dendritic protein transport relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0099640 ! regulates axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:31Z [Term] id: GO:1905127 name: negative regulation of axo-dendritic protein transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "down regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "down regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "down-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "down-regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "downregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "downregulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "inhibition of axo-dendritic protein transport" NARROW [GOC:TermGenie] synonym: "inhibition of axonal protein transport" NARROW [GOC:TermGenie] synonym: "negative regulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0090317 ! negative regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0099640 ! negatively regulates axo-dendritic protein transport relationship: RO:0002212 GO:0099640 ! negatively regulates axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:40Z [Term] id: GO:1905128 name: positive regulation of axo-dendritic protein transport def: "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "activation of axo-dendritic protein transport" NARROW [GOC:TermGenie] synonym: "activation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "positive regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "up regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "up regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "up-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "up-regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "upregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "upregulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0090316 ! positive regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0099640 ! positively regulates axo-dendritic protein transport relationship: RO:0002213 GO:0099640 ! positively regulates axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:48Z [Term] id: GO:1905139 name: apical ectodermal ridge formation def: "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:TermGenie, PMID:18359901, PMID:9323126, PMID:9596583] synonym: "AER formation" RELATED [GOC:TermGenie] synonym: "apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: RO:0002297 UBERON:0004356 ! results in formation of anatomical entity apical ectodermal ridge relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0035107 ! appendage morphogenesis relationship: RO:0002297 UBERON:0004356 ! results in formation of anatomical entity apical ectodermal ridge created_by: dph creation_date: 2016-04-13T11:46:40Z [Term] id: GO:1905140 name: regulation of apical ectodermal ridge formation def: "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "regulation of AER formation" RELATED [GOC:TermGenie] synonym: "regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905139 ! regulates apical ectodermal ridge formation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:1905139 ! regulates apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:40Z [Term] id: GO:1905141 name: negative regulation of apical ectodermal ridge formation def: "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "down regulation of AER formation" RELATED [GOC:TermGenie] synonym: "down regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "down regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "down-regulation of AER formation" RELATED [GOC:TermGenie] synonym: "down-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "downregulation of AER formation" RELATED [GOC:TermGenie] synonym: "downregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "inhibition of AER formation" RELATED [GOC:TermGenie] synonym: "inhibition of apical ectodermal ridge formation" NARROW [GOC:TermGenie] synonym: "inhibition of apical epidermal ridge formation" NARROW [GOC:TermGenie] synonym: "inhibition of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "negative regulation of AER formation" RELATED [GOC:TermGenie] synonym: "negative regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "negative regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905139 ! negatively regulates apical ectodermal ridge formation relationship: RO:0002212 GO:1905139 ! negatively regulates apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:48Z [Term] id: GO:1905142 name: positive regulation of apical ectodermal ridge formation def: "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "activation of AER formation" RELATED [GOC:TermGenie] synonym: "positive regulation of AER formation" RELATED [GOC:TermGenie] synonym: "positive regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "positive regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "up regulation of AER formation" RELATED [GOC:TermGenie] synonym: "up regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "up-regulation of AER formation" RELATED [GOC:TermGenie] synonym: "up-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "upregulation of AER formation" RELATED [GOC:TermGenie] synonym: "upregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905139 ! positively regulates apical ectodermal ridge formation relationship: RO:0002213 GO:1905139 ! positively regulates apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:57Z [Term] id: GO:1905144 name: response to acetylcholine def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] is_a: GO:1901698 ! response to nitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine relationship: RO:0004009 CHEBI:15355 ! has primary input acetylcholine created_by: dos creation_date: 2016-04-14T08:54:49Z [Term] id: GO:1905145 name: cellular response to acetylcholine def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] is_a: GO:1901699 ! cellular response to nitrogen compound is_a: GO:1901701 ! cellular response to oxygen-containing compound is_a: GO:1905144 ! response to acetylcholine intersection_of: GO:0070887 ! cellular response to chemical stimulus intersection_of: RO:0004009 CHEBI:15355 ! has primary input acetylcholine created_by: dos creation_date: 2016-04-14T08:54:58Z [Term] id: GO:1905147 name: regulation of smooth muscle hypertrophy def: "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014895 ! regulates smooth muscle hypertrophy relationship: RO:0002211 GO:0014895 ! regulates smooth muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bc creation_date: 2016-04-15T12:47:07Z [Term] id: GO:1905148 name: negative regulation of smooth muscle hypertrophy def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "down regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "inhibition of smooth muscle hypertrophy" NARROW [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014895 ! negatively regulates smooth muscle hypertrophy relationship: RO:0002212 GO:0014895 ! negatively regulates smooth muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bc creation_date: 2016-04-15T12:47:16Z [Term] id: GO:1905149 name: positive regulation of smooth muscle hypertrophy def: "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "activation of smooth muscle hypertrophy" NARROW [GOC:TermGenie] synonym: "up regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014895 ! positively regulates smooth muscle hypertrophy relationship: RO:0002213 GO:0014895 ! positively regulates smooth muscle hypertrophy property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bc creation_date: 2016-04-15T12:47:24Z [Term] id: GO:1905153 name: regulation of membrane invagination def: "Any process that modulates the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010324 ! regulates membrane invagination relationship: RO:0002211 GO:0010324 ! regulates membrane invagination created_by: bf creation_date: 2016-04-18T15:43:54Z [Term] id: GO:1905154 name: negative regulation of membrane invagination def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] synonym: "down regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "down-regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "downregulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "inhibition of membrane invagination" NARROW [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1905153 ! regulation of membrane invagination intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010324 ! negatively regulates membrane invagination relationship: RO:0002212 GO:0010324 ! negatively regulates membrane invagination created_by: bf creation_date: 2016-04-18T15:44:04Z [Term] id: GO:1905155 name: positive regulation of membrane invagination def: "Any process that activates or increases the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] synonym: "activation of membrane invagination" NARROW [GOC:TermGenie] synonym: "up regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "up-regulation of membrane invagination" EXACT [GOC:TermGenie] synonym: "upregulation of membrane invagination" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905153 ! regulation of membrane invagination intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010324 ! positively regulates membrane invagination relationship: RO:0002213 GO:0010324 ! positively regulates membrane invagination created_by: bf creation_date: 2016-04-18T15:44:12Z [Term] id: GO:1905207 name: regulation of cardiocyte differentiation def: "Any process that modulates the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035051 ! regulates cardiocyte differentiation relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0035051 ! regulates cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:01Z [Term] id: GO:1905208 name: negative regulation of cardiocyte differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "down regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of cardiocyte differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of heart cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035051 ! negatively regulates cardiocyte differentiation relationship: RO:0002212 GO:0035051 ! negatively regulates cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:09Z [Term] id: GO:1905209 name: positive regulation of cardiocyte differentiation def: "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "activation of cardiac cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of cardiocyte differentiation" NARROW [GOC:TermGenie] synonym: "activation of heart cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035051 ! positively regulates cardiocyte differentiation relationship: RO:0002213 GO:0035051 ! positively regulates cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:16Z [Term] id: GO:1905213 name: negative regulation of mitotic chromosome condensation def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:23219725] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:1902340 ! negative regulation of chromosome condensation is_a: GO:1903379 ! regulation of mitotic chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007076 ! negatively regulates mitotic chromosome condensation relationship: RO:0002212 GO:0007076 ! negatively regulates mitotic chromosome condensation created_by: vw creation_date: 2016-06-03T08:41:08Z [Term] id: GO:1905223 name: epicardium morphogenesis def: "The developmental process by which an epicardium is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] synonym: "heart epicardium morphogenesis" EXACT [GOC:TermGenie] synonym: "pericardium visceral mesothelium morphogenesis" RELATED [GOC:TermGenie] synonym: "visceral serous pericardium of heart morphogenesis" EXACT [GOC:TermGenie] synonym: "visceral serous pericardium proper morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0002348 ! results in morphogenesis of epicardium relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002298 UBERON:0002348 ! results in morphogenesis of epicardium created_by: rl creation_date: 2016-06-07T10:02:32Z [Term] id: GO:1905268 name: negative regulation of chromatin organization alt_id: GO:0045798 alt_id: GO:1903309 def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "down regulation of chromatin assembly or disassembly" RELATED [] synonym: "down regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin assembly or disassembly" RELATED [] synonym: "down-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin assembly or disassembly" RELATED [] synonym: "downregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "inhibition of chromatin assembly or disassembly" NARROW [] synonym: "inhibition of chromatin organisation" NARROW [GOC:TermGenie] synonym: "inhibition of chromatin organization" NARROW [GOC:TermGenie] synonym: "inhibition of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] synonym: "negative regulation of chromatin assembly or disassembly" RELATED [] synonym: "negative regulation of chromatin assembly/disassembly" EXACT [] synonym: "negative regulation of chromatin modification" RELATED [] synonym: "negative regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902275 ! regulation of chromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006325 ! negatively regulates chromatin organization relationship: RO:0002212 GO:0006325 ! negatively regulates chromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI created_by: pr creation_date: 2016-06-15T20:14:47Z [Term] id: GO:1905269 name: positive regulation of chromatin organization alt_id: GO:0045799 alt_id: GO:1903310 def: "Any process that activates or increases the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "activation of chromatin assembly or disassembly" NARROW [] synonym: "activation of chromatin organisation" NARROW [GOC:TermGenie] synonym: "activation of chromatin organization" NARROW [GOC:TermGenie] synonym: "activation of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] synonym: "positive regulation of chromatin assembly or disassembly" RELATED [] synonym: "positive regulation of chromatin assembly/disassembly" RELATED [] synonym: "positive regulation of chromatin modification" RELATED [] synonym: "positive regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "stimulation of chromatin assembly or disassembly" NARROW [] synonym: "up regulation of chromatin assembly or disassembly" RELATED [] synonym: "up regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin assembly or disassembly" RELATED [] synonym: "up-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin assembly or disassembly" EXACT [] synonym: "upregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:1902275 ! regulation of chromatin organization is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006325 ! positively regulates chromatin organization relationship: RO:0002213 GO:0006325 ! positively regulates chromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI created_by: pr creation_date: 2016-06-15T20:14:56Z [Term] id: GO:1905276 name: regulation of epithelial tube formation def: "Any process that modulates the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072175 ! regulates epithelial tube formation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0072175 ! regulates epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:41Z [Term] id: GO:1905277 name: negative regulation of epithelial tube formation def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "down regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "inhibition of epithelial tube formation" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072175 ! negatively regulates epithelial tube formation relationship: RO:0002212 GO:0072175 ! negatively regulates epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:49Z [Term] id: GO:1905278 name: positive regulation of epithelial tube formation def: "Any process that activates or increases the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "activation of epithelial tube formation" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial tube formation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072175 ! positively regulates epithelial tube formation relationship: RO:0002213 GO:0072175 ! positively regulates epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:57Z [Term] id: GO:1905288 name: vascular associated smooth muscle cell apoptotic process def: "Any apoptotic process in a vascular associated smooth muscle cell." [GO_REF:0000085, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034390 ! smooth muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0000359 ! occurs in vascular associated smooth muscle cell relationship: BFO:0000066 CL:0000359 ! occurs in vascular associated smooth muscle cell created_by: rph creation_date: 2016-06-23T13:24:20Z [Term] id: GO:1905292 name: regulation of neural crest cell differentiation def: "Any process that modulates the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0014033 ! regulates neural crest cell differentiation relationship: in_taxon NCBITaxon:89593 ! Craniata relationship: RO:0002211 GO:0014033 ! regulates neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:01Z [Term] id: GO:1905293 name: negative regulation of neural crest cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "down regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of neural crest cell differentiation" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0014033 ! negatively regulates neural crest cell differentiation relationship: RO:0002212 GO:0014033 ! negatively regulates neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:09Z [Term] id: GO:1905294 name: positive regulation of neural crest cell differentiation def: "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "activation of neural crest cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0014033 ! positively regulates neural crest cell differentiation relationship: RO:0002213 GO:0014033 ! positively regulates neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:16Z [Term] id: GO:1905298 name: regulation of intestinal epithelial cell development def: "Any process that modulates the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060576 ! regulates intestinal epithelial cell development relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002211 GO:0060576 ! regulates intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:40:47Z [Term] id: GO:1905299 name: negative regulation of intestinal epithelial cell development def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "down regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "inhibition of intestinal epithelial cell development" NARROW [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060576 ! negatively regulates intestinal epithelial cell development relationship: RO:0002212 GO:0060576 ! negatively regulates intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:40:55Z [Term] id: GO:1905300 name: positive regulation of intestinal epithelial cell development def: "Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "activation of intestinal epithelial cell development" NARROW [GOC:TermGenie] synonym: "up regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060576 ! positively regulates intestinal epithelial cell development relationship: RO:0002213 GO:0060576 ! positively regulates intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:41:02Z [Term] id: GO:1905304 name: regulation of cardiac myofibril assembly def: "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "regulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0060284 ! regulation of cell development is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902115 ! regulation of organelle assembly is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055003 ! regulates cardiac myofibril assembly relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0055003 ! regulates cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:01:49Z [Term] id: GO:1905305 name: negative regulation of cardiac myofibril assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "down regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "downregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "inhibition of cardiac myofibril assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cardiac myofibril development" NARROW [GOC:TermGenie] synonym: "inhibition of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055003 ! negatively regulates cardiac myofibril assembly relationship: RO:0002212 GO:0055003 ! negatively regulates cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:01:58Z [Term] id: GO:1905306 name: positive regulation of cardiac myofibril assembly def: "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "activation of cardiac myofibril assembly" NARROW [GOC:TermGenie] synonym: "activation of cardiac myofibril development" NARROW [GOC:TermGenie] synonym: "activation of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "positive regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "up regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "upregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1902905 ! positive regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055003 ! positively regulates cardiac myofibril assembly relationship: RO:0002213 GO:0055003 ! positively regulates cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:02:07Z [Term] id: GO:1905310 name: regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis def: "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003253 ! regulates cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003253 ! regulates cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:26Z [Term] id: GO:1905311 name: negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003253 ! negatively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: RO:0002212 GO:0003253 ! negatively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:35Z [Term] id: GO:1905312 name: positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis def: "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "activation of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003253 ! positively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: RO:0002213 GO:0003253 ! positively regulates cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:43Z [Term] id: GO:1905315 name: cell proliferation involved in endocardial cushion morphogenesis def: "Any cell proliferation that is involved in endocardial cushion morphogenesis." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20652948] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0003203 ! endocardial cushion morphogenesis created_by: rl creation_date: 2016-07-12T13:56:36Z [Term] id: GO:1905319 name: mesenchymal stem cell migration def: "The orderly movement of a mesenchymal stem cell from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:24924806, PMID:25181476] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: RO:0002565 CL:0000134 ! results in movement of mesenchymal stem cell relationship: RO:0002565 CL:0000134 ! results in movement of mesenchymal stem cell property_value: RO:0002161 NCBITaxon:4890 created_by: sl creation_date: 2016-07-14T17:13:02Z [Term] id: GO:1905320 name: regulation of mesenchymal stem cell migration def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905319 ! regulates mesenchymal stem cell migration relationship: RO:0002211 GO:1905319 ! regulates mesenchymal stem cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: sl creation_date: 2016-07-15T22:19:14Z [Term] id: GO:1905321 name: negative regulation of mesenchymal stem cell migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "down regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of mesenchymal stem cell migration" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905319 ! negatively regulates mesenchymal stem cell migration relationship: RO:0002212 GO:1905319 ! negatively regulates mesenchymal stem cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: sl creation_date: 2016-07-15T22:19:22Z [Term] id: GO:1905322 name: positive regulation of mesenchymal stem cell migration def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "activation of mesenchymal stem cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905319 ! positively regulates mesenchymal stem cell migration relationship: RO:0002213 GO:1905319 ! positively regulates mesenchymal stem cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: sl creation_date: 2016-07-15T22:19:29Z [Term] id: GO:1905330 name: regulation of morphogenesis of an epithelium def: "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002009 ! regulates morphogenesis of an epithelium relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0002009 ! regulates morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:13:49Z [Term] id: GO:1905331 name: negative regulation of morphogenesis of an epithelium def: "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "down regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "downregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "inhibition of epithelium morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of morphogenesis of an epithelium" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002009 ! negatively regulates morphogenesis of an epithelium relationship: RO:0002212 GO:0002009 ! negatively regulates morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:13:57Z [Term] id: GO:1905332 name: positive regulation of morphogenesis of an epithelium def: "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "activation of epithelium morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of morphogenesis of an epithelium" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "upregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002009 ! positively regulates morphogenesis of an epithelium relationship: RO:0002213 GO:0002009 ! positively regulates morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:14:05Z [Term] id: GO:1905349 name: ciliary transition zone assembly def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:21725307, PMID:23644468, PMID:24448408, PMID:26595381, PMID:26982032] synonym: "cilial transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilial transition zone formation" EXACT [GOC:TermGenie] synonym: "ciliary transition zone formation" EXACT [GOC:TermGenie] synonym: "cilium transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilium transition zone formation" EXACT [GOC:TermGenie] is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: RO:0002588 GO:0035869 ! results in assembly of ciliary transition zone relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0060271 ! cilium assembly relationship: RO:0002588 GO:0035869 ! results in assembly of ciliary transition zone property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: pr creation_date: 2016-08-04T14:49:43Z [Term] id: GO:1905383 name: protein localization to presynapse def: "A process in which a protein is transported to, or maintained in, a location within a presynapse." [GO_REF:0000087, GOC:TermGenie, PMID:24449494] synonym: "protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "recruitment of presynaptic proteins" EXACT [PMID:24449494] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0098793 ! has target end location presynapse relationship: RO:0002339 GO:0098793 ! has target end location presynapse created_by: dos creation_date: 2016-08-18T14:42:59Z [Term] id: GO:1905384 name: regulation of protein localization to presynapse def: "Any process that modulates the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905383 ! regulates protein localization to presynapse relationship: RO:0002211 GO:1905383 ! regulates protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:00Z [Term] id: GO:1905385 name: negative regulation of protein localization to presynapse def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "down regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905383 ! negatively regulates protein localization to presynapse relationship: RO:0002212 GO:1905383 ! negatively regulates protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:08Z [Term] id: GO:1905386 name: positive regulation of protein localization to presynapse def: "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "activation of protein localisation in presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization in presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization to presynapse" NARROW [GOC:TermGenie] synonym: "activation of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902474 ! positive regulation of protein localization to synapse is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905383 ! positively regulates protein localization to presynapse relationship: RO:0002213 GO:1905383 ! positively regulates protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:21Z [Term] id: GO:1905432 name: regulation of retrograde trans-synaptic signaling by neuropeptide def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099082 ! regulates retrograde trans-synaptic signaling by neuropeptide relationship: RO:0002211 GO:0099082 ! regulates retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:56:47Z [Term] id: GO:1905433 name: negative regulation of retrograde trans-synaptic signaling by neuropeptide def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "down regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "down-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "downregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "inhibition of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] synonym: "inhibition of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] synonym: "negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0099082 ! negatively regulates retrograde trans-synaptic signaling by neuropeptide relationship: RO:0002212 GO:0099082 ! negatively regulates retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:56:55Z [Term] id: GO:1905434 name: positive regulation of retrograde trans-synaptic signaling by neuropeptide def: "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "activation of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] synonym: "positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] synonym: "up regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "up-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "upregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0099082 ! positively regulates retrograde trans-synaptic signaling by neuropeptide relationship: RO:0002213 GO:0099082 ! positively regulates retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:57:02Z [Term] id: GO:1905453 name: regulation of myeloid progenitor cell differentiation def: "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002318 ! regulates myeloid progenitor cell differentiation relationship: RO:0002211 GO:0002318 ! regulates myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:18Z [Term] id: GO:1905454 name: negative regulation of myeloid progenitor cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002318 ! negatively regulates myeloid progenitor cell differentiation relationship: RO:0002212 GO:0002318 ! negatively regulates myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:26Z [Term] id: GO:1905455 name: positive regulation of myeloid progenitor cell differentiation def: "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "activation of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002318 ! positively regulates myeloid progenitor cell differentiation relationship: RO:0002213 GO:0002318 ! positively regulates myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:33Z [Term] id: GO:1905456 name: regulation of lymphoid progenitor cell differentiation def: "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002320 ! regulates lymphoid progenitor cell differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0002320 ! regulates lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:40Z [Term] id: GO:1905457 name: negative regulation of lymphoid progenitor cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002320 ! negatively regulates lymphoid progenitor cell differentiation relationship: RO:0002212 GO:0002320 ! negatively regulates lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:48Z [Term] id: GO:1905458 name: positive regulation of lymphoid progenitor cell differentiation def: "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "activation of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002320 ! positively regulates lymphoid progenitor cell differentiation relationship: RO:0002213 GO:0002320 ! positively regulates lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:55Z [Term] id: GO:1905459 name: regulation of vascular associated smooth muscle cell apoptotic process def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1905288 ! regulates vascular associated smooth muscle cell apoptotic process relationship: RO:0002211 GO:1905288 ! regulates vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:33:54Z [Term] id: GO:1905460 name: negative regulation of vascular associated smooth muscle cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "down regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034392 ! negative regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1905288 ! negatively regulates vascular associated smooth muscle cell apoptotic process relationship: RO:0002212 GO:1905288 ! negatively regulates vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:34:03Z [Term] id: GO:1905461 name: positive regulation of vascular associated smooth muscle cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "activation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "activation of VSMC apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034393 ! positive regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1905288 ! positively regulates vascular associated smooth muscle cell apoptotic process relationship: RO:0002213 GO:1905288 ! positively regulates vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:34:10Z [Term] id: GO:1905475 name: regulation of protein localization to membrane def: "Any process that modulates the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072657 ! regulates protein localization to membrane relationship: RO:0002211 GO:0072657 ! regulates protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:03Z [Term] id: GO:1905476 name: negative regulation of protein localization to membrane def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "down regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to membrane" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072657 ! negatively regulates protein localization to membrane relationship: RO:0002212 GO:0072657 ! negatively regulates protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:10Z [Term] id: GO:1905477 name: positive regulation of protein localization to membrane def: "Any process that activates or increases the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "activation of protein localisation in membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to membrane" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to membrane" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072657 ! positively regulates protein localization to membrane relationship: RO:0002213 GO:0072657 ! positively regulates protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:18Z [Term] id: GO:1905483 name: regulation of motor neuron migration def: "Any process that modulates the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097475 ! regulates motor neuron migration relationship: RO:0002211 GO:0097475 ! regulates motor neuron migration created_by: hbye creation_date: 2016-09-23T12:49:54Z [Term] id: GO:1905484 name: negative regulation of motor neuron migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "down regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "down-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "downregulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "inhibition of motor neuron migration" NARROW [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001223 ! negative regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097475 ! negatively regulates motor neuron migration relationship: RO:0002212 GO:0097475 ! negatively regulates motor neuron migration created_by: hbye creation_date: 2016-09-23T12:50:11Z [Term] id: GO:1905485 name: positive regulation of motor neuron migration def: "Any process that activates or increases the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "activation of motor neuron migration" NARROW [GOC:TermGenie] synonym: "up regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "up-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "upregulation of motor neuron migration" EXACT [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001224 ! positive regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097475 ! positively regulates motor neuron migration relationship: RO:0002213 GO:0097475 ! positively regulates motor neuron migration created_by: hbye creation_date: 2016-09-23T12:50:19Z [Term] id: GO:1905492 name: positive regulation of branching morphogenesis of a nerve def: "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "activation of branching morphogenesis of a nerve" NARROW [GOC:TermGenie] synonym: "up regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "up-regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "upregulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048755 ! positively regulates branching morphogenesis of a nerve relationship: RO:0002213 GO:0048755 ! positively regulates branching morphogenesis of a nerve created_by: hbye creation_date: 2016-09-23T14:11:52Z [Term] id: GO:1905503 name: regulation of motile cilium assembly def: "Any process that modulates the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "regulation of motile primary cilium assembly" RELATED [] synonym: "regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "regulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:1902017 ! regulation of cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044458 ! regulates motile cilium assembly relationship: RO:0002211 GO:0044458 ! regulates motile cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2016-09-27T18:27:47Z [Term] id: GO:1905504 name: negative regulation of motile cilium assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "down regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "down regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "down regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "down-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "downregulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "downregulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "inhibition of motile primary cilia assembly" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilia formation" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilium assembly" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilium formation" NARROW [GOC:TermGenie] synonym: "inhibition of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "inhibition of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilium assembly" RELATED [] synonym: "negative regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "negative regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:1902018 ! negative regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044458 ! negatively regulates motile cilium assembly relationship: RO:0002212 GO:0044458 ! negatively regulates motile cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2016-09-27T18:27:55Z [Term] id: GO:1905505 name: positive regulation of motile cilium assembly def: "Any process that activates or increases the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "activation of motile primary cilia assembly" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilia formation" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilium assembly" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilium formation" NARROW [GOC:TermGenie] synonym: "activation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "activation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilium assembly" RELATED [] synonym: "positive regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "positive regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "up regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "up regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "up-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "upregulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "upregulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:0045724 ! positive regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044458 ! positively regulates motile cilium assembly relationship: RO:0002213 GO:0044458 ! positively regulates motile cilium assembly property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4751 property_value: RO:0002161 NCBITaxon:5782 created_by: krc creation_date: 2016-09-27T18:28:03Z [Term] id: GO:1905516 name: positive regulation of fertilization def: "Any process that activates or increases the frequency, rate or extent of fertilization." [GO_REF:0000058, GOC:hbye, GOC:TermGenie, PMID:27564576] synonym: "activation of fertilization" NARROW [GOC:TermGenie] synonym: "activation of syngamy" NARROW [GOC:TermGenie] synonym: "positive regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up-regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up-regulation of syngamy" EXACT [GOC:TermGenie] synonym: "upregulation of fertilization" EXACT [GOC:TermGenie] synonym: "upregulation of syngamy" EXACT [GOC:TermGenie] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0009566 ! positively regulates fertilization relationship: RO:0002213 GO:0009566 ! positively regulates fertilization created_by: pr creation_date: 2016-09-30T14:32:32Z [Term] id: GO:1905553 name: regulation of blood vessel branching def: "Any process that modulates the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001569 ! regulates branching involved in blood vessel morphogenesis relationship: RO:0002211 GO:0001569 ! regulates branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:33Z [Term] id: GO:1905554 name: negative regulation of blood vessel branching def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "down-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "downregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "inhibition of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "negative regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0016525 ! negative regulation of angiogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001569 ! negatively regulates branching involved in blood vessel morphogenesis relationship: RO:0002212 GO:0001569 ! negatively regulates branching involved in blood vessel morphogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/29454" xsd:anyURI created_by: nc creation_date: 2016-10-12T14:19:41Z [Term] id: GO:1905555 name: positive regulation of blood vessel branching def: "Any process that activates or increases the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "activation of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "positive regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "up-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "upregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of patterning of blood vessels" EXACT [GOC:TermGenie] is_a: GO:0045766 ! positive regulation of angiogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001569 ! positively regulates branching involved in blood vessel morphogenesis relationship: RO:0002213 GO:0001569 ! positively regulates branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:49Z [Term] id: GO:1905557 name: regulation of mitotic nuclear envelope disassembly def: "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010549 ! regulation of membrane disassembly is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007077 ! regulates mitotic nuclear membrane disassembly relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: RO:0002211 GO:0007077 ! regulates mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:14:57Z [Term] id: GO:1905558 name: negative regulation of mitotic nuclear envelope disassembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "down regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007077 ! negatively regulates mitotic nuclear membrane disassembly relationship: RO:0002212 GO:0007077 ! negatively regulates mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:15:08Z [Term] id: GO:1905559 name: positive regulation of mitotic nuclear envelope disassembly def: "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "activation of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007077 ! positively regulates mitotic nuclear membrane disassembly relationship: RO:0002213 GO:0007077 ! positively regulates mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:15:17Z [Term] id: GO:1905562 name: regulation of vascular endothelial cell proliferation def: "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] is_a: GO:0001936 ! regulation of endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0101023 ! regulates vascular endothelial cell proliferation relationship: RO:0002211 GO:0101023 ! regulates vascular endothelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: nc creation_date: 2016-10-17T09:24:17Z [Term] id: GO:1905563 name: negative regulation of vascular endothelial cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0001937 ! negative regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0101023 ! negatively regulates vascular endothelial cell proliferation relationship: RO:0002212 GO:0101023 ! negatively regulates vascular endothelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: nc creation_date: 2016-10-17T09:24:26Z [Term] id: GO:1905564 name: positive regulation of vascular endothelial cell proliferation def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "activation of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0001938 ! positive regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0101023 ! positively regulates vascular endothelial cell proliferation relationship: RO:0002213 GO:0101023 ! positively regulates vascular endothelial cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: nc creation_date: 2016-10-17T09:24:35Z [Term] id: GO:1905606 name: regulation of presynapse assembly def: "Any process that modulates the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] subset: goslim_synapse synonym: "regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099174 ! regulation of presynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0099054 ! regulates presynapse assembly relationship: RO:0002211 GO:0099054 ! regulates presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:13Z [Term] id: GO:1905607 name: negative regulation of presynapse assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "down regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "inhibition of presynapse assembly" NARROW [GOC:TermGenie] synonym: "inhibition of presynapse biogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of presynaptic terminal assembly" NARROW [GOC:TermGenie] synonym: "negative regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051964 ! negative regulation of synapse assembly is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0099054 ! negatively regulates presynapse assembly relationship: RO:0002212 GO:0099054 ! negatively regulates presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:20Z [Term] id: GO:1905608 name: positive regulation of presynapse assembly def: "Any process that activates or increases the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "activation of presynapse assembly" NARROW [GOC:TermGenie] synonym: "activation of presynapse biogenesis" NARROW [GOC:TermGenie] synonym: "activation of presynaptic terminal assembly" NARROW [GOC:TermGenie] synonym: "positive regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0099054 ! positively regulates presynapse assembly relationship: RO:0002213 GO:0099054 ! positively regulates presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:28Z [Term] id: GO:1905627 name: regulation of serotonin biosynthetic process def: "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0042427 ! regulates serotonin biosynthetic process relationship: RO:0002211 GO:0042427 ! regulates serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:20Z [Term] id: GO:1905628 name: negative regulation of serotonin biosynthetic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "down regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of serotonin anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin formation" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0042427 ! negatively regulates serotonin biosynthetic process relationship: RO:0002212 GO:0042427 ! negatively regulates serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:28Z [Term] id: GO:1905629 name: positive regulation of serotonin biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "activation of serotonin anabolism" NARROW [GOC:TermGenie] synonym: "activation of serotonin biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of serotonin biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of serotonin formation" NARROW [GOC:TermGenie] synonym: "activation of serotonin synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0042427 ! positively regulates serotonin biosynthetic process relationship: RO:0002213 GO:0042427 ! positively regulates serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:36Z [Term] id: GO:1905634 name: regulation of protein localization to chromatin def: "Any process that modulates the frequency, rate or extent of protein localization to chromatin." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] synonym: "regulation of protein localisation to chromatin" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071168 ! regulates protein localization to chromatin relationship: RO:0002211 GO:0071168 ! regulates protein localization to chromatin created_by: pga creation_date: 2016-11-01T16:33:52Z [Term] id: GO:1905651 name: regulation of artery morphogenesis def: "Any process that modulates the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048844 ! regulates artery morphogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0048844 ! regulates artery morphogenesis created_by: rph creation_date: 2016-11-09T12:19:37Z [Term] id: GO:1905652 name: negative regulation of artery morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "down regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of arterial morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of arteriogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of artery morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:1905651 ! regulation of artery morphogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048844 ! negatively regulates artery morphogenesis relationship: RO:0002212 GO:0048844 ! negatively regulates artery morphogenesis created_by: rph creation_date: 2016-11-09T12:19:53Z [Term] id: GO:1905653 name: positive regulation of artery morphogenesis def: "Any process that activates or increases the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "activation of arterial morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of arteriogenesis" NARROW [GOC:TermGenie] synonym: "activation of artery morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of artery morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048844 ! positively regulates artery morphogenesis relationship: RO:0002213 GO:0048844 ! positively regulates artery morphogenesis created_by: rph creation_date: 2016-11-09T12:20:01Z [Term] id: GO:1905690 name: nucleus disassembly def: "The disaggregation of a nucleus into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] synonym: "cell nucleus disassembly" EXACT [GOC:TermGenie] is_a: GO:0006997 ! nucleus organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: RO:0002590 GO:0005634 ! results in disassembly of nucleus relationship: RO:0002590 GO:0005634 ! results in disassembly of nucleus created_by: pr creation_date: 2016-11-14T13:38:57Z [Term] id: GO:1905720 name: cytoplasmic microtubule bundle def: "Any microtubule bundle that is part of a cytoplasm." [GO_REF:0000064, GOC:TermGenie, PMID:11007487, PMID:26124291] synonym: "microtubule bundle of cytoplasm" EXACT [GOC:TermGenie] synonym: "microtubule fascicle of cytoplasm" EXACT [GOC:TermGenie] is_a: GO:0097427 ! microtubule bundle intersection_of: GO:0097427 ! microtubule bundle intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm created_by: mah creation_date: 2016-11-24T16:52:02Z [Term] id: GO:1905748 name: hard palate morphogenesis def: "The developmental process by which a hard palate is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:23419067] synonym: "palatum durum morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: RO:0002298 UBERON:0003216 ! results in morphogenesis of hard palate relationship: in_taxon NCBITaxon:32524 ! Amniota relationship: RO:0002298 UBERON:0003216 ! results in morphogenesis of hard palate created_by: pga creation_date: 2016-12-09T12:22:24Z [Term] id: GO:1905755 name: protein localization to cytoplasmic microtubule def: "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule." [GO_REF:0000087, GOC:TermGenie, PMID:15177031] synonym: "protein localisation to cytoplasmic microtubule" EXACT [GOC:TermGenie] is_a: GO:0035372 ! protein localization to microtubule intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0005881 ! has target end location cytoplasmic microtubule relationship: RO:0002339 GO:0005881 ! has target end location cytoplasmic microtubule created_by: mah creation_date: 2016-12-12T15:31:07Z [Term] id: GO:1905770 name: regulation of mesodermal cell differentiation def: "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048333 ! regulates mesodermal cell differentiation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0048333 ! regulates mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:13Z [Term] id: GO:1905771 name: negative regulation of mesodermal cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "down regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of mesoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of mesodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048333 ! negatively regulates mesodermal cell differentiation relationship: RO:0002212 GO:0048333 ! negatively regulates mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:23Z [Term] id: GO:1905772 name: positive regulation of mesodermal cell differentiation def: "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "activation of mesoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of mesodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048333 ! positively regulates mesodermal cell differentiation relationship: RO:0002213 GO:0048333 ! positively regulates mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:32Z [Term] id: GO:1905787 name: regulation of detection of mechanical stimulus involved in sensory perception of touch def: "Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] synonym: "regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0051931 ! regulation of sensory perception intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0050976 ! regulates detection of mechanical stimulus involved in sensory perception of touch relationship: RO:0002211 GO:0050976 ! regulates detection of mechanical stimulus involved in sensory perception of touch created_by: hbye creation_date: 2017-01-09T15:11:04Z [Term] id: GO:1905788 name: negative regulation of detection of mechanical stimulus involved in sensory perception of touch def: "Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] synonym: "down regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "down regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down-regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down-regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "downregulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "downregulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "downregulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "inhibition of detection of mechanical stimulus involved in sensory perception of touch" NARROW [GOC:TermGenie] synonym: "inhibition of perception of touch, detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "inhibition of perception of touch, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "inhibition of perception of touch, sensory transduction of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "inhibition of sensory detection of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "inhibition of sensory transduction of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "inhibition of tactition, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "negative regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "negative regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "negative regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "negative regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "negative regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "negative regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:1905787 ! regulation of detection of mechanical stimulus involved in sensory perception of touch intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050976 ! negatively regulates detection of mechanical stimulus involved in sensory perception of touch relationship: RO:0002212 GO:0050976 ! negatively regulates detection of mechanical stimulus involved in sensory perception of touch created_by: hbye creation_date: 2017-01-09T15:11:14Z [Term] id: GO:1905789 name: positive regulation of detection of mechanical stimulus involved in sensory perception of touch def: "Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] synonym: "activation of detection of mechanical stimulus involved in sensory perception of touch" NARROW [GOC:TermGenie] synonym: "activation of perception of touch, detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "activation of perception of touch, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "activation of perception of touch, sensory transduction of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "activation of sensory detection of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "activation of sensory transduction of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "activation of tactition, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "positive regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "positive regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "positive regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "positive regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "positive regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "positive regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "up regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up-regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up-regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "upregulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "upregulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "upregulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:1905787 ! regulation of detection of mechanical stimulus involved in sensory perception of touch intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0050976 ! positively regulates detection of mechanical stimulus involved in sensory perception of touch relationship: RO:0002213 GO:0050976 ! positively regulates detection of mechanical stimulus involved in sensory perception of touch created_by: hbye creation_date: 2017-01-09T15:11:23Z [Term] id: GO:1905806 name: regulation of synapse pruning def: "Any process that modulates the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] subset: goslim_synapse synonym: "regulation of synapse clearance" EXACT [] synonym: "regulation of synapse disassembly" EXACT syngo_official_label [] synonym: "regulation of synapse elimination" EXACT [] synonym: "regulation of synapse removal" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0098883 ! regulates synapse pruning relationship: RO:0002211 GO:0098883 ! regulates synapse pruning created_by: tb creation_date: 2017-01-11T22:03:15Z [Term] id: GO:1905807 name: negative regulation of synapse pruning def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "inhibition of synapse disassembly" NARROW [GOC:TermGenie] synonym: "regulation of synapse clearance" BROAD [] synonym: "regulation of synapse disassembly" BROAD [] synonym: "regulation of synapse elimination" BROAD [] synonym: "regulation of synapse removal" BROAD [] is_a: GO:1905806 ! regulation of synapse pruning is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0098883 ! negatively regulates synapse pruning relationship: RO:0002212 GO:0098883 ! negatively regulates synapse pruning created_by: tb creation_date: 2017-01-11T22:03:24Z [Term] id: GO:1905808 name: positive regulation of synapse pruning def: "Any process that activates or increases the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "activation of synapse disassembly" NARROW [GOC:TermGenie] synonym: "regulation of synapse clearance" BROAD [] synonym: "regulation of synapse disassembly" BROAD [] synonym: "regulation of synapse elimination" BROAD [] synonym: "regulation of synapse removal" BROAD [] synonym: "up regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of synapse disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905806 ! regulation of synapse pruning intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0098883 ! positively regulates synapse pruning relationship: RO:0002213 GO:0098883 ! positively regulates synapse pruning created_by: tb creation_date: 2017-01-11T22:03:33Z [Term] id: GO:1905809 name: negative regulation of synapse organization def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "down regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of synapse development" EXACT [GOC:TermGenie] synonym: "downregulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organization" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of synapse development" NARROW [GOC:TermGenie] synonym: "inhibition of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of synapse organisation" NARROW [GOC:TermGenie] synonym: "inhibition of synapse organization" NARROW [GOC:TermGenie] synonym: "inhibition of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of synapse development" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0050808 ! negatively regulates synapse organization relationship: RO:0002212 GO:0050808 ! negatively regulates synapse organization created_by: tb creation_date: 2017-01-11T22:03:41Z [Term] id: GO:1905821 name: positive regulation of chromosome condensation def: "Any process that activates or increases the frequency, rate or extent of chromosome condensation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17268547] synonym: "activation of chromosome condensation" NARROW [GOC:TermGenie] synonym: "activation of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "activation of nuclear chromosome condensation" NARROW [GOC:TermGenie] synonym: "positive regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030261 ! positively regulates chromosome condensation relationship: RO:0002213 GO:0030261 ! positively regulates chromosome condensation created_by: bhm creation_date: 2017-01-13T14:13:44Z [Term] id: GO:1905833 name: negative regulation of microtubule nucleation def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." [GO_REF:0000058, GOC:TermGenie, PMID:27689799] synonym: "down regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule nucleation" NARROW [GOC:TermGenie] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031115 ! negative regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007020 ! negatively regulates microtubule nucleation relationship: RO:0002212 GO:0007020 ! negatively regulates microtubule nucleation created_by: hbye creation_date: 2017-01-17T12:00:56Z [Term] id: GO:1905867 name: epididymis development def: "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12388089] synonym: "epididymus development" EXACT [GOC:TermGenie] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0001301 ! results in development of epididymis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002296 UBERON:0001301 ! results in development of epididymis created_by: sl creation_date: 2017-01-27T00:00:33Z [Term] id: GO:1905871 name: regulation of protein localization to cell leading edge def: "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:1902463 ! regulates protein localization to cell leading edge relationship: RO:0002211 GO:1902463 ! regulates protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:34:55Z [Term] id: GO:1905872 name: negative regulation of protein localization to cell leading edge def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "down regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to cell leading edge" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:1902463 ! negatively regulates protein localization to cell leading edge relationship: RO:0002212 GO:1902463 ! negatively regulates protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:35:04Z [Term] id: GO:1905873 name: positive regulation of protein localization to cell leading edge def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "activation of protein localisation in cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localization in cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localization to cell leading edge" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:1902463 ! positively regulates protein localization to cell leading edge relationship: RO:0002213 GO:1902463 ! positively regulates protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:35:13Z [Term] id: GO:1905879 name: regulation of oogenesis def: "Any process that modulates the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048477 ! regulates oogenesis relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0048477 ! regulates oogenesis created_by: hbye creation_date: 2017-01-31T09:31:05Z [Term] id: GO:1905880 name: negative regulation of oogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "down regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of ovum development" EXACT [GOC:TermGenie] synonym: "down-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "downregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of ovum development" EXACT [GOC:TermGenie] synonym: "inhibition of oogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of ovum development" NARROW [GOC:TermGenie] synonym: "negative regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048477 ! negatively regulates oogenesis relationship: RO:0002212 GO:0048477 ! negatively regulates oogenesis created_by: hbye creation_date: 2017-01-31T09:31:15Z [Term] id: GO:1905881 name: positive regulation of oogenesis def: "Any process that activates or increases the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "activation of oogenesis" NARROW [GOC:TermGenie] synonym: "activation of ovum development" NARROW [GOC:TermGenie] synonym: "positive regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "upregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048477 ! positively regulates oogenesis relationship: RO:0002213 GO:0048477 ! positively regulates oogenesis created_by: hbye creation_date: 2017-01-31T09:31:23Z [Term] id: GO:1905899 name: regulation of smooth muscle tissue development def: "Any process that modulates the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048745 ! regulates smooth muscle tissue development relationship: RO:0002211 GO:0048745 ! regulates smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:16Z [Term] id: GO:1905900 name: negative regulation of smooth muscle tissue development def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "down regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of smooth muscle tissue development" NARROW [GOC:TermGenie] is_a: GO:1901862 ! negative regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048745 ! negatively regulates smooth muscle tissue development relationship: RO:0002212 GO:0048745 ! negatively regulates smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:24Z [Term] id: GO:1905901 name: positive regulation of smooth muscle tissue development def: "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "activation of smooth muscle tissue development" NARROW [GOC:TermGenie] synonym: "up regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:1901863 ! positive regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048745 ! positively regulates smooth muscle tissue development relationship: RO:0002213 GO:0048745 ! positively regulates smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:33Z [Term] id: GO:1905902 name: regulation of mesoderm formation def: "Any process that modulates the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001707 ! regulates mesoderm formation relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0001707 ! regulates mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:20Z [Term] id: GO:1905903 name: negative regulation of mesoderm formation def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "down regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "inhibition of mesoderm formation" NARROW [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000381 ! negative regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001707 ! negatively regulates mesoderm formation relationship: RO:0002212 GO:0001707 ! negatively regulates mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:29Z [Term] id: GO:1905904 name: positive regulation of mesoderm formation def: "Any process that activates or increases the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "activation of mesoderm formation" NARROW [GOC:TermGenie] synonym: "up regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm formation" EXACT [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000382 ! positive regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001707 ! positively regulates mesoderm formation relationship: RO:0002213 GO:0001707 ! positively regulates mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:38Z [Term] id: GO:1905921 name: regulation of acetylcholine biosynthetic process def: "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008292 ! regulates acetylcholine biosynthetic process relationship: RO:0002211 GO:0008292 ! regulates acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:30Z [Term] id: GO:1905922 name: negative regulation of acetylcholine biosynthetic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "down regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of acetylcholine anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine formation" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008292 ! negatively regulates acetylcholine biosynthetic process relationship: RO:0002212 GO:0008292 ! negatively regulates acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:39Z [Term] id: GO:1905923 name: positive regulation of acetylcholine biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "activation of acetylcholine anabolism" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine formation" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0060409 ! positive regulation of acetylcholine metabolic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008292 ! positively regulates acetylcholine biosynthetic process relationship: RO:0002213 GO:0008292 ! positively regulates acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:48Z [Term] id: GO:1905936 name: regulation of germ cell proliferation def: "Any process that modulates the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0036093 ! regulates germ cell proliferation relationship: RO:0002211 GO:0036093 ! regulates germ cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: hbye creation_date: 2017-02-09T14:51:31Z [Term] id: GO:1905937 name: negative regulation of germ cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of germ cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0036093 ! negatively regulates germ cell proliferation relationship: RO:0002212 GO:0036093 ! negatively regulates germ cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: hbye creation_date: 2017-02-09T14:51:41Z [Term] id: GO:1905938 name: positive regulation of germ cell proliferation def: "Any process that activates or increases the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "activation of germ cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of germ cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0036093 ! positively regulates germ cell proliferation relationship: RO:0002213 GO:0036093 ! positively regulates germ cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: hbye creation_date: 2017-02-09T14:51:51Z [Term] id: GO:1905939 name: regulation of gonad development def: "Any process that modulates the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008406 ! regulates gonad development relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0008406 ! regulates gonad development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: hbye creation_date: 2017-02-09T17:01:50Z [Term] id: GO:1905940 name: negative regulation of gonad development def: "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of gonad development" EXACT [GOC:TermGenie] synonym: "downregulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of gonad development" NARROW [GOC:TermGenie] synonym: "inhibition of gonadogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008406 ! negatively regulates gonad development relationship: RO:0002212 GO:0008406 ! negatively regulates gonad development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: hbye creation_date: 2017-02-09T17:01:59Z [Term] id: GO:1905941 name: positive regulation of gonad development def: "Any process that activates or increases the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "activation of gonad development" NARROW [GOC:TermGenie] synonym: "activation of gonadogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of gonad development" EXACT [GOC:TermGenie] synonym: "upregulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008406 ! positively regulates gonad development relationship: RO:0002213 GO:0008406 ! positively regulates gonad development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: hbye creation_date: 2017-02-09T17:02:08Z [Term] id: GO:1905952 name: regulation of lipid localization def: "Any process that modulates the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0010876 ! regulates lipid localization relationship: RO:0002211 GO:0010876 ! regulates lipid localization created_by: rz creation_date: 2017-02-21T12:12:22Z [Term] id: GO:1905953 name: negative regulation of lipid localization def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "down regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localization" EXACT [GOC:TermGenie] synonym: "inhibition of lipid localisation" NARROW [GOC:TermGenie] synonym: "inhibition of lipid localization" NARROW [GOC:TermGenie] synonym: "negative regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0010876 ! negatively regulates lipid localization relationship: RO:0002212 GO:0010876 ! negatively regulates lipid localization created_by: rz creation_date: 2017-02-21T12:12:41Z [Term] id: GO:1905954 name: positive regulation of lipid localization def: "Any process that activates or increases the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "activation of lipid localisation" NARROW [GOC:TermGenie] synonym: "activation of lipid localization" NARROW [GOC:TermGenie] synonym: "positive regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localization" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0010876 ! positively regulates lipid localization relationship: RO:0002213 GO:0010876 ! positively regulates lipid localization created_by: rz creation_date: 2017-02-21T12:12:49Z [Term] id: GO:1905955 name: negative regulation of endothelial tube morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "down regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial tube morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061154 ! negatively regulates endothelial tube morphogenesis relationship: RO:0002212 GO:0061154 ! negatively regulates endothelial tube morphogenesis created_by: rph creation_date: 2017-02-21T15:17:31Z [Term] id: GO:1905956 name: positive regulation of endothelial tube morphogenesis def: "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "activation of endothelial tube morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061154 ! positively regulates endothelial tube morphogenesis relationship: RO:0002213 GO:0061154 ! positively regulates endothelial tube morphogenesis created_by: rph creation_date: 2017-02-21T15:17:39Z [Term] id: GO:1990009 name: retinal cell apoptotic process alt_id: GO:0046674 def: "Any apoptotic process in a retinal cell." [GOC:mtg_apoptosis, PMID:15558487, PMID:24664675] synonym: "induction of retinal programmed cell death" RELATED [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0009004 ! occurs in retinal cell relationship: BFO:0000066 CL:0009004 ! occurs in retinal cell property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-12-12T10:15:08Z [Term] id: GO:1990010 name: compound eye retinal cell apoptotic process def: "Any apoptotic process in a compound eye retinal cell." [GOC:mtg_apoptosis, PMID:12021768] is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: BFO:0000066 CL:0009001 ! occurs in compound eye retinal cell relationship: BFO:0000066 CL:0009001 ! occurs in compound eye retinal cell property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2012-12-12T10:21:07Z [Term] id: GO:1990048 name: anterograde neuronal dense core vesicle transport def: "The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse." [GOC:kmv, PMID:23358451] subset: goslim_synapse synonym: "anterograde dense core granule trafficking" EXACT [] synonym: "anterograde dense core granule transport" EXACT [] is_a: GO:0008089 ! anterograde axonal transport is_a: GO:0047496 ! vesicle transport along microtubule is_a: GO:0099519 ! dense core granule cytoskeletal transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm intersection_of: RO:0002339 GO:0098793 ! has target end location presynapse intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0098992 ! has primary input neuronal dense core vesicle relationship: RO:0004009 GO:0098992 ! has primary input neuronal dense core vesicle [Term] id: GO:1990049 name: retrograde neuronal dense core vesicle transport def: "The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body." [GOC:kmv, PMID:23358451, PMID:24762653] subset: goslim_synapse synonym: "retrograde dense core granule trafficking" EXACT [] synonym: "retrograde dense core granule transport" EXACT [] is_a: GO:0008090 ! retrograde axonal transport is_a: GO:0047496 ! vesicle transport along microtubule is_a: GO:0099519 ! dense core granule cytoskeletal transport intersection_of: GO:0006810 ! transport intersection_of: BFO:0000066 GO:1904115 ! occurs in axon cytoplasm intersection_of: RO:0002338 GO:0098793 ! has target start location presynapse intersection_of: RO:0002341 GO:0005874 ! results in transport along microtubule intersection_of: RO:0004009 GO:0098992 ! has primary input neuronal dense core vesicle relationship: RO:0004009 GO:0098992 ! has primary input neuronal dense core vesicle created_by: pr creation_date: 2013-02-19T13:31:44Z [Term] id: GO:1990182 name: exosomal secretion def: "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:hjd, PMID:10572093, PMID:12154376, PMID:16773132, PMID:18617898] synonym: "exosomal protein secretion" NARROW [PMID:18617898] synonym: "exosomal secretory pathway" EXACT [PMID:18617898] synonym: "extracellular vesicular exosome secretion" EXACT [GOC:hjd] synonym: "multi-vesicular body fusion with plasma membrane" EXACT [] synonym: "secretion of exosome" EXACT [PMID:18617898] is_a: GO:0006887 ! exocytosis is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0006887 ! exocytosis intersection_of: RO:0004009 GO:0070062 ! has primary input extracellular exosome relationship: part_of GO:0097734 ! extracellular exosome biogenesis relationship: RO:0004009 GO:0070062 ! has primary input extracellular exosome property_value: RO:0002161 NCBITaxon:4890 created_by: hjd creation_date: 2013-09-04T21:08:14Z [Term] id: GO:1990234 name: transferase complex def: "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." [GOC:bhm, PMID:16540464] is_a: GO:1902494 ! catalytic complex intersection_of: GO:1902494 ! catalytic complex intersection_of: capable_of GO:0016740 ! transferase activity relationship: capable_of GO:0016740 ! transferase activity created_by: bhm creation_date: 2013-11-12T13:20:12Z [Term] id: GO:1990280 name: RNA localization to chromatin def: "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin." [GOC:dos, GOC:mah, PMID:22582262] synonym: "RNA localisation to chromatin" EXACT [] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: RO:0002339 GO:0000785 ! has target end location chromatin relationship: RO:0002339 GO:0000785 ! has target end location chromatin created_by: mah creation_date: 2014-01-30T15:55:34Z [Term] id: GO:1990351 name: transporter complex def: "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells." [GOC:bhm, PMID:15449578] comment: An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay). is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0005215 ! transporter activity relationship: capable_of GO:0005215 ! transporter activity created_by: bhm creation_date: 2014-03-26T14:23:27Z [Term] id: GO:1990375 name: baculum development def: "The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure." [GOC:sl, PMID:21471296] synonym: "os penis development" EXACT [GOC:sl] synonym: "penile bone development" EXACT [GOC:sl] synonym: "penis bone development" EXACT [GOC:sl] is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: RO:0002296 UBERON:0006435 ! results in development of os penis relationship: in_taxon NCBITaxon:40674 ! Mammalia relationship: RO:0002296 UBERON:0006435 ! results in development of os penis created_by: sl creation_date: 2014-05-01T23:59:13Z [Term] id: GO:1990502 name: dense core granule maturation def: "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis." [GOC:kmv, PMID:22654674] synonym: "dense core vesicle maturation" EXACT [] is_a: GO:0061792 ! secretory granule maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: RO:0002299 GO:0031045 ! results in maturation of dense core granule relationship: RO:0002299 GO:0031045 ! results in maturation of dense core granule property_value: RO:0002161 NCBITaxon:4890 created_by: kmv creation_date: 2014-09-30T20:35:11Z [Term] id: GO:1990580 name: regulation of cytoplasmic translational termination def: "Any process that modulates the frequency, rate or extent of cytoplasmic translational termination." [PMID:11570975] is_a: GO:0006449 ! regulation of translational termination is_a: GO:2000765 ! regulation of cytoplasmic translation intersection_of: GO:0050789 ! regulation of biological process intersection_of: RO:0002211 GO:0002184 ! regulates cytoplasmic translational termination relationship: RO:0002211 GO:0002184 ! regulates cytoplasmic translational termination created_by: vw creation_date: 2014-12-10T15:48:55Z [Term] id: GO:1990705 name: cholangiocyte proliferation def: "The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water." [PMID:24434010] synonym: "hepatoblast proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:1000488 ! acts on population of cholangiocyte relationship: RO:0012003 CL:1000488 ! acts on population of cholangiocyte property_value: RO:0002161 NCBITaxon:4751 creation_date: 2015-03-16T23:23:50Z [Term] id: GO:1990748 name: cellular detoxification def: "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw] is_a: GO:0009987 ! cellular process is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: BFO:0000066 CL:0000000 ! occurs in cell relationship: BFO:0000066 CL:0000000 ! occurs in cell relationship: part_of GO:0097237 ! cellular response to toxic substance created_by: vw creation_date: 2015-05-18T16:17:46Z [Term] id: GO:1990765 name: colon smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum." [PMID:24170253] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: BFO:0000066 UBERON:0001155 ! occurs in colon relationship: BFO:0000066 UBERON:0001155 ! occurs in colon relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014827 ! intestine smooth muscle contraction created_by: sl creation_date: 2015-06-10T18:29:21Z [Term] id: GO:1990768 name: gastric mucosal blood circulation def: "The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products." [PMID:10807413] synonym: "stomach mucosal blood circulation" EXACT [] is_a: GO:0008015 ! blood circulation intersection_of: GO:0008015 ! blood circulation intersection_of: BFO:0000066 UBERON:0004786 ! occurs in gastrointestinal system mucosa relationship: BFO:0000066 UBERON:0004786 ! occurs in gastrointestinal system mucosa property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: sl creation_date: 2015-06-10T20:11:09Z [Term] id: GO:1990770 name: small intestine smooth muscle contraction def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine." [PMID:11991626] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: BFO:0000066 UBERON:0002108 ! occurs in small intestine relationship: BFO:0000066 UBERON:0002108 ! occurs in small intestine relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014827 ! intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T18:02:33Z [Term] id: GO:1990778 name: protein localization to cell periphery def: "A process in which a protein is transported to, or maintained in, the cell periphery." [PMID:18216290] is_a: GO:0008104 ! intracellular protein localization intersection_of: GO:0008104 ! intracellular protein localization intersection_of: RO:0002339 GO:0071944 ! has target end location cell periphery relationship: RO:0002339 GO:0071944 ! has target end location cell periphery creation_date: 2015-06-18T22:37:39Z [Term] id: GO:1990849 name: vacuolar localization def: "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell." [PMID:26283797] synonym: "maintenance of vacuolar localization" EXACT [] synonym: "maintenance of vacuolar location" NARROW [] synonym: "maintenance of vacuole localization" EXACT [] synonym: "maintenance of vacuole location" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: RO:0004009 GO:0005773 ! has primary input vacuole relationship: RO:0004009 GO:0005773 ! has primary input vacuole property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22182" xsd:anyURI created_by: mcc creation_date: 2015-09-10T08:16:02Z [Term] id: GO:1990863 name: acinar cell proliferation def: "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)." [PMID:9788538] synonym: "acinic cell proliferation" EXACT [] synonym: "acinous cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000622 ! acts on population of acinar cell relationship: RO:0012003 CL:0000622 ! acts on population of acinar cell property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-09-25T14:26:09Z [Term] id: GO:1990874 name: vascular associated smooth muscle cell proliferation def: "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [PMID:23246467] synonym: "vascular smooth muscle cell proliferation" EXACT [] synonym: "VSMC proliferation" EXACT [] is_a: GO:0048659 ! smooth muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: RO:0012003 CL:0000359 ! acts on population of vascular associated smooth muscle cell relationship: RO:0012003 CL:0000359 ! acts on population of vascular associated smooth muscle cell property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-09-29T16:34:59Z [Term] id: GO:1990904 name: ribonucleoprotein complex alt_id: GO:0030529 alt_id: GO:1990903 def: "A macromolecular complex that contains both RNA and protein molecules." [GOC:krc, GOC:vesicles] subset: goslim_pir synonym: "extracellular ribonucleoprotein complex" NARROW [] synonym: "intracellular ribonucleoprotein complex" NARROW [] synonym: "protein-RNA complex" EXACT [] synonym: "RNA-protein complex" EXACT [] synonym: "RNP" EXACT [] xref: Wikipedia:Ribonucleoprotein is_a: GO:0032991 ! protein-containing complex relationship: has_part CHEBI:33697 ! ribonucleic acid created_by: pr creation_date: 2015-11-19T12:26:37Z [Term] id: GO:1990917 name: ooplasm def: "The cytoplasm of an ovum." [PMID:19022436] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of CL:0000025 ! egg cell relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of CL:0000025 ! egg cell created_by: sl creation_date: 2015-12-10T21:40:16Z [Term] id: GO:2000018 name: regulation of male gonad development def: "Any process that modulates the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "regulation of testicular development" EXACT [GOC:obol] synonym: "regulation of testis development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008584 ! regulates male gonad development relationship: RO:0002211 GO:0008584 ! regulates male gonad development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2010-07-15T03:29:05Z [Term] id: GO:2000019 name: negative regulation of male gonad development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "negative regulation of testicular development" EXACT [GOC:obol] synonym: "negative regulation of testis development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008584 ! negatively regulates male gonad development relationship: RO:0002212 GO:0008584 ! negatively regulates male gonad development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2010-07-15T03:29:10Z [Term] id: GO:2000020 name: positive regulation of male gonad development def: "Any process that activates or increases the frequency, rate or extent of male gonad development." [GOC:obol] synonym: "positive regulation of testicular development" EXACT [GOC:obol] synonym: "positive regulation of testis development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008584 ! positively regulates male gonad development relationship: RO:0002213 GO:0008584 ! positively regulates male gonad development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2010-07-15T03:29:13Z [Term] id: GO:2000026 name: regulation of multicellular organismal development def: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007275 ! regulates multicellular organism development relationship: in_taxon NCBITaxon:131567 ! cellular organisms relationship: RO:0002211 GO:0007275 ! regulates multicellular organism development property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: tb creation_date: 2010-08-05T11:25:59Z [Term] id: GO:2000027 name: regulation of animal organ morphogenesis def: "Any process that modulates the frequency, rate or extent of animal organ morphogenesis." [GOC:obol] synonym: "regulation of histogenesis and organogenesis" RELATED [GOC:obol] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0009887 ! regulates animal organ morphogenesis relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0009887 ! regulates animal organ morphogenesis created_by: tb creation_date: 2010-08-05T11:26:27Z [Term] id: GO:2000035 name: regulation of stem cell division def: "Any process that modulates the frequency, rate or extent of stem cell division." [GOC:obol] synonym: "regulation of stem cell renewal" EXACT [GOC:obol] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0017145 ! regulates stem cell division relationship: RO:0002211 GO:0017145 ! regulates stem cell division property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: tb creation_date: 2010-08-05T11:34:53Z [Term] id: GO:2000036 name: regulation of stem cell population maintenance def: "Any process that modulates the frequency, rate or extent of stem cell population maintenance." [GOC:obol] synonym: "regulation of maintenance of pluripotency" RELATED [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0019827 ! regulates stem cell population maintenance relationship: RO:0002211 GO:0019827 ! regulates stem cell population maintenance property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: tb creation_date: 2010-08-05T11:35:25Z [Term] id: GO:2000061 name: regulation of ureter smooth muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072193 ! regulates ureter smooth muscle cell differentiation relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0072193 ! regulates ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:16Z [Term] id: GO:2000062 name: negative regulation of ureter smooth muscle cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072193 ! negatively regulates ureter smooth muscle cell differentiation relationship: RO:0002212 GO:0072193 ! negatively regulates ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:23Z [Term] id: GO:2000063 name: positive regulation of ureter smooth muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072193 ! positively regulates ureter smooth muscle cell differentiation relationship: RO:0002213 GO:0072193 ! positively regulates ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:28Z [Term] id: GO:2000068 name: regulation of defense response to insect def: "Any process that modulates the frequency, rate or extent of defense response to insect." [GOC:obol] synonym: "regulation of physiological defense response to insect" EXACT [GOC:obol] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002213 ! regulates defense response to insect relationship: RO:0002211 GO:0002213 ! regulates defense response to insect property_value: RO:0002161 NCBITaxon:4895 created_by: tb creation_date: 2010-08-23T09:30:00Z [Term] id: GO:2000074 name: regulation of type B pancreatic cell development def: "Any process that modulates the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "regulation of pancreatic beta cell development" EXACT [GOC:obol] xref: Reactome:R-HSA-211163 "AKT-mediated inactivation of FOXO1A" is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003323 ! regulates type B pancreatic cell development relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003323 ! regulates type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:19:37Z [Term] id: GO:2000077 name: negative regulation of type B pancreatic cell development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "negative regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "negative regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003323 ! negatively regulates type B pancreatic cell development relationship: RO:0002212 GO:0003323 ! negatively regulates type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:21:17Z [Term] id: GO:2000078 name: positive regulation of type B pancreatic cell development def: "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "positive regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "positive regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003323 ! positively regulates type B pancreatic cell development relationship: RO:0002213 GO:0003323 ! positively regulates type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:21:19Z [Term] id: GO:2000084 name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis def: "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061261 ! regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: RO:0002211 GO:0061261 ! regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:06:41Z [Term] id: GO:2000085 name: negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "negative regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061261 ! negatively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: RO:0002212 GO:0061261 ! negatively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:08:21Z [Term] id: GO:2000086 name: positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis def: "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "positive regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061261 ! positively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: RO:0002213 GO:0061261 ! positively regulates mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:08:24Z [Term] id: GO:2000106 name: regulation of leukocyte apoptotic process def: "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "regulation of leukocyte apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071887 ! regulates leukocyte apoptotic process relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0071887 ! regulates leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:05Z [Term] id: GO:2000107 name: negative regulation of leukocyte apoptotic process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "negative regulation of leukocyte apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071887 ! negatively regulates leukocyte apoptotic process relationship: RO:0002212 GO:0071887 ! negatively regulates leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:09Z [Term] id: GO:2000108 name: positive regulation of leukocyte apoptotic process def: "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "positive regulation of leukocyte apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071887 ! positively regulates leukocyte apoptotic process relationship: RO:0002213 GO:0071887 ! positively regulates leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:12Z [Term] id: GO:2000114 name: regulation of establishment of cell polarity def: "Any process that modulates the frequency, rate or extent of establishment of cell polarity." [GOC:dph] synonym: "regulation of bud site selection/establishment of cell polarity" RELATED [GOC:obol] synonym: "regulation of cell polarization" EXACT [GOC:obol] is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030010 ! regulates establishment of cell polarity relationship: RO:0002211 GO:0030010 ! regulates establishment of cell polarity created_by: dph creation_date: 2010-09-16T01:22:36Z [Term] id: GO:2000136 name: regulation of cell proliferation involved in heart morphogenesis def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061323 ! regulates cell proliferation involved in heart morphogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0061323 ! regulates cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:53Z [Term] id: GO:2000137 name: negative regulation of cell proliferation involved in heart morphogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061323 ! negatively regulates cell proliferation involved in heart morphogenesis relationship: RO:0002212 GO:0061323 ! negatively regulates cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:55Z [Term] id: GO:2000138 name: positive regulation of cell proliferation involved in heart morphogenesis def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061323 ! positively regulates cell proliferation involved in heart morphogenesis relationship: RO:0002213 GO:0061323 ! positively regulates cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:57Z [Term] id: GO:2000145 name: regulation of cell motility def: "Any process that modulates the frequency, rate or extent of cell motility." [GOC:mah] synonym: "regulation of cell locomotion" EXACT [GOC:obol] synonym: "regulation of cell movement" RELATED [GOC:obol] synonym: "regulation of movement of a cell" EXACT [GOC:obol] xref: Reactome:R-HSA-6785631 "ERBB2 Regulates Cell Motility" is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048870 ! regulates cell motility relationship: RO:0002211 GO:0048870 ! regulates cell motility property_value: RO:0002161 NCBITaxon:451864 created_by: mah creation_date: 2010-10-01T09:41:21Z [Term] id: GO:2000146 name: negative regulation of cell motility def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." [GOC:mah] synonym: "negative regulation of cell locomotion" EXACT [GOC:obol] synonym: "negative regulation of cell movement" RELATED [GOC:obol] synonym: "negative regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048870 ! negatively regulates cell motility relationship: RO:0002212 GO:0048870 ! negatively regulates cell motility property_value: RO:0002161 NCBITaxon:451864 created_by: mah creation_date: 2010-10-01T09:41:26Z [Term] id: GO:2000147 name: positive regulation of cell motility def: "Any process that activates or increases the frequency, rate or extent of cell motility." [GOC:mah] synonym: "positive regulation of cell locomotion" EXACT [GOC:obol] synonym: "positive regulation of cell movement" RELATED [GOC:obol] synonym: "positive regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048870 ! positively regulates cell motility relationship: RO:0002213 GO:0048870 ! positively regulates cell motility property_value: RO:0002161 NCBITaxon:451864 created_by: mah creation_date: 2010-10-01T09:41:30Z [Term] id: GO:2000155 name: positive regulation of cilium-dependent cell motility def: "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl] synonym: "positive regulation of ciliary cell motility" RELATED [] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060285 ! positively regulates cilium-dependent cell motility relationship: RO:0002213 GO:0060285 ! positively regulates cilium-dependent cell motility property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:451864 property_value: RO:0002161 NCBITaxon:5782 created_by: mah creation_date: 2010-10-04T12:41:05Z [Term] id: GO:2000172 name: regulation of branching morphogenesis of a nerve def: "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048755 ! regulates branching morphogenesis of a nerve relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0048755 ! regulates branching morphogenesis of a nerve created_by: rl creation_date: 2010-10-07T12:07:54Z [Term] id: GO:2000173 name: negative regulation of branching morphogenesis of a nerve def: "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048755 ! negatively regulates branching morphogenesis of a nerve relationship: RO:0002212 GO:0048755 ! negatively regulates branching morphogenesis of a nerve created_by: rl creation_date: 2010-10-07T12:07:56Z [Term] id: GO:2000174 name: regulation of pro-T cell differentiation def: "Any process that modulates the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002572 ! regulates pro-T cell differentiation relationship: RO:0002211 GO:0002572 ! regulates pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:30Z [Term] id: GO:2000175 name: negative regulation of pro-T cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "negative regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045581 ! negative regulation of T cell differentiation is_a: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002572 ! negatively regulates pro-T cell differentiation relationship: RO:0002212 GO:0002572 ! negatively regulates pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:33Z [Term] id: GO:2000176 name: positive regulation of pro-T cell differentiation def: "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "positive regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045582 ! positive regulation of T cell differentiation is_a: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002572 ! positively regulates pro-T cell differentiation relationship: RO:0002213 GO:0002572 ! positively regulates pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:35Z [Term] id: GO:2000177 name: regulation of neural precursor cell proliferation def: "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061351 ! regulates neural precursor cell proliferation relationship: RO:0002211 GO:0061351 ! regulates neural precursor cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2010-10-13T12:40:41Z [Term] id: GO:2000178 name: negative regulation of neural precursor cell proliferation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061351 ! negatively regulates neural precursor cell proliferation relationship: RO:0002212 GO:0061351 ! negatively regulates neural precursor cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2010-10-13T12:40:43Z [Term] id: GO:2000179 name: positive regulation of neural precursor cell proliferation def: "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061351 ! positively regulates neural precursor cell proliferation relationship: RO:0002213 GO:0061351 ! positively regulates neural precursor cell proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2010-10-13T12:40:45Z [Term] id: GO:2000181 name: negative regulation of blood vessel morphogenesis def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis." [GOC:dph, GOC:yaf] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901343 ! negative regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048514 ! negatively regulates blood vessel morphogenesis relationship: RO:0002212 GO:0048514 ! negatively regulates blood vessel morphogenesis created_by: dph creation_date: 2010-10-13T12:46:31Z [Term] id: GO:2000194 name: regulation of female gonad development def: "Any process that modulates the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "regulation of ovarian development" EXACT [GOC:obol] synonym: "regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008585 ! regulates female gonad development relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0008585 ! regulates female gonad development created_by: yaf creation_date: 2010-10-19T10:45:34Z [Term] id: GO:2000195 name: negative regulation of female gonad development def: "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "negative regulation of ovarian development" EXACT [GOC:obol] synonym: "negative regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008585 ! negatively regulates female gonad development relationship: RO:0002212 GO:0008585 ! negatively regulates female gonad development created_by: yaf creation_date: 2010-10-19T10:45:38Z [Term] id: GO:2000196 name: positive regulation of female gonad development def: "Any process that activates or increases the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "positive regulation of ovarian development" EXACT [GOC:obol] synonym: "positive regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008585 ! positively regulates female gonad development relationship: RO:0002213 GO:0008585 ! positively regulates female gonad development created_by: yaf creation_date: 2010-10-19T10:45:41Z [Term] id: GO:2000197 name: regulation of ribonucleoprotein complex localization def: "Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization." [GOC:mah] synonym: "regulation of cellular ribonucleoprotein complex localization" EXACT [GOC:obol] synonym: "regulation of establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:obol] synonym: "regulation of ribonucleoprotein complex localisation" EXACT [GOC:mah] synonym: "regulation of RNP localization" EXACT [GOC:obol] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0071166 ! regulates ribonucleoprotein complex localization relationship: RO:0002211 GO:0071166 ! regulates ribonucleoprotein complex localization created_by: mah creation_date: 2010-10-26T10:35:48Z [Term] id: GO:2000198 name: negative regulation of ribonucleoprotein complex localization def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization." [GOC:mah] synonym: "negative regulation of cellular ribonucleoprotein complex localization" EXACT [GOC:obol] synonym: "negative regulation of establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:obol] synonym: "negative regulation of ribonucleoprotein complex localisation" EXACT [GOC:mah] synonym: "negative regulation of RNP localization" EXACT [GOC:obol] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0071166 ! negatively regulates ribonucleoprotein complex localization relationship: RO:0002212 GO:0071166 ! negatively regulates ribonucleoprotein complex localization created_by: mah creation_date: 2010-10-26T10:35:52Z [Term] id: GO:2000199 name: positive regulation of ribonucleoprotein complex localization def: "Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization." [GOC:mah] synonym: "positive regulation of cellular ribonucleoprotein complex localization" EXACT [GOC:obol] synonym: "positive regulation of establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:obol] synonym: "positive regulation of ribonucleoprotein complex localisation" EXACT [GOC:mah] synonym: "positive regulation of RNP localization" EXACT [GOC:obol] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0071166 ! positively regulates ribonucleoprotein complex localization relationship: RO:0002213 GO:0071166 ! positively regulates ribonucleoprotein complex localization created_by: mah creation_date: 2010-10-26T10:35:55Z [Term] id: GO:2000226 name: regulation of pancreatic A cell differentiation def: "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003310 ! regulates pancreatic A cell differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0003310 ! regulates pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:37Z [Term] id: GO:2000227 name: negative regulation of pancreatic A cell differentiation def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "negative regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003310 ! negatively regulates pancreatic A cell differentiation relationship: RO:0002212 GO:0003310 ! negatively regulates pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:40Z [Term] id: GO:2000228 name: positive regulation of pancreatic A cell differentiation def: "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "positive regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003310 ! positively regulates pancreatic A cell differentiation relationship: RO:0002213 GO:0003310 ! positively regulates pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:42Z [Term] id: GO:2000238 name: regulation of tRNA export from nucleus def: "Any process that modulates the frequency, rate or extent of tRNA export from nucleus." [GOC:mah] synonym: "regulation of tRNA export from cell nucleus" EXACT [GOC:obol] synonym: "regulation of tRNA export out of nucleus" EXACT [GOC:obol] synonym: "regulation of tRNA transport from nucleus to cytoplasm" EXACT [GOC:obol] synonym: "regulation of tRNA-nucleus export" EXACT [GOC:obol] is_a: GO:0046831 ! regulation of RNA export from nucleus is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0006409 ! regulates tRNA export from nucleus relationship: RO:0002211 GO:0006409 ! regulates tRNA export from nucleus created_by: mah creation_date: 2010-11-10T12:39:33Z [Term] id: GO:2000239 name: negative regulation of tRNA export from nucleus def: "Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus." [GOC:mah] synonym: "negative regulation of tRNA export from cell nucleus" EXACT [GOC:obol] synonym: "negative regulation of tRNA export out of nucleus" EXACT [GOC:obol] synonym: "negative regulation of tRNA transport from nucleus to cytoplasm" EXACT [GOC:obol] synonym: "negative regulation of tRNA-nucleus export" EXACT [GOC:obol] is_a: GO:0046832 ! negative regulation of RNA export from nucleus is_a: GO:2000198 ! negative regulation of ribonucleoprotein complex localization is_a: GO:2000238 ! regulation of tRNA export from nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0006409 ! negatively regulates tRNA export from nucleus relationship: RO:0002212 GO:0006409 ! negatively regulates tRNA export from nucleus created_by: mah creation_date: 2010-11-10T12:39:36Z [Term] id: GO:2000240 name: positive regulation of tRNA export from nucleus def: "Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus." [GOC:mah] synonym: "positive regulation of tRNA export from cell nucleus" EXACT [GOC:obol] synonym: "positive regulation of tRNA export out of nucleus" EXACT [GOC:obol] synonym: "positive regulation of tRNA transport from nucleus to cytoplasm" EXACT [GOC:obol] synonym: "positive regulation of tRNA-nucleus export" EXACT [GOC:obol] is_a: GO:0046833 ! positive regulation of RNA export from nucleus is_a: GO:2000199 ! positive regulation of ribonucleoprotein complex localization is_a: GO:2000238 ! regulation of tRNA export from nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0006409 ! positively regulates tRNA export from nucleus relationship: RO:0002213 GO:0006409 ! positively regulates tRNA export from nucleus created_by: mah creation_date: 2010-11-10T12:39:38Z [Term] id: GO:2000241 name: regulation of reproductive process def: "Any process that modulates the frequency, rate or extent of reproductive process." [GOC:mah] subset: gocheck_do_not_annotate is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0022414 ! regulates reproductive process relationship: RO:0002211 GO:0022414 ! regulates reproductive process created_by: mah creation_date: 2010-11-10T02:44:02Z [Term] id: GO:2000242 name: negative regulation of reproductive process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0022414 ! negatively regulates reproductive process relationship: RO:0002212 GO:0022414 ! negatively regulates reproductive process created_by: mah creation_date: 2010-11-10T02:44:05Z [Term] id: GO:2000243 name: positive regulation of reproductive process def: "Any process that activates or increases the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0022414 ! positively regulates reproductive process relationship: RO:0002213 GO:0022414 ! positively regulates reproductive process created_by: mah creation_date: 2010-11-10T02:44:08Z [Term] id: GO:2000248 name: negative regulation of establishment or maintenance of neuroblast polarity def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity." [GOC:obol] synonym: "negative regulation of establishment and/or maintenance of neuroblast cell polarity" EXACT [GOC:obol] is_a: GO:0010454 ! negative regulation of cell fate commitment is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity is_a: GO:0045769 ! negative regulation of asymmetric cell division intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0045196 ! negatively regulates establishment or maintenance of neuroblast polarity relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002212 GO:0045196 ! negatively regulates establishment or maintenance of neuroblast polarity created_by: vw creation_date: 2010-11-11T11:40:34Z [Term] id: GO:2000254 name: regulation of male germ cell proliferation def: "Any process that modulates the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905936 ! regulation of germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002176 ! regulates male germ cell proliferation relationship: RO:0002211 GO:0002176 ! regulates male germ cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2010-11-18T09:29:44Z [Term] id: GO:2000255 name: negative regulation of male germ cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905937 ! negative regulation of germ cell proliferation is_a: GO:2000242 ! negative regulation of reproductive process is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002176 ! negatively regulates male germ cell proliferation relationship: RO:0002212 GO:0002176 ! negatively regulates male germ cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2010-11-18T09:29:47Z [Term] id: GO:2000256 name: positive regulation of male germ cell proliferation def: "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905938 ! positive regulation of germ cell proliferation is_a: GO:2000243 ! positive regulation of reproductive process is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002176 ! positively regulates male germ cell proliferation relationship: RO:0002213 GO:0002176 ! positively regulates male germ cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2010-11-18T09:29:50Z [Term] id: GO:2000269 name: regulation of fibroblast apoptotic process def: "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "regulation of fibroblast apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0044346 ! regulates fibroblast apoptotic process relationship: RO:0002211 GO:0044346 ! regulates fibroblast apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: jl creation_date: 2010-11-23T01:07:23Z [Term] id: GO:2000270 name: negative regulation of fibroblast apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "negative regulation of fibroblast apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0044346 ! negatively regulates fibroblast apoptotic process relationship: RO:0002212 GO:0044346 ! negatively regulates fibroblast apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: jl creation_date: 2010-11-23T01:07:27Z [Term] id: GO:2000271 name: positive regulation of fibroblast apoptotic process def: "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "positive regulation of fibroblast apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0044346 ! positively regulates fibroblast apoptotic process relationship: RO:0002213 GO:0044346 ! positively regulates fibroblast apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: jl creation_date: 2010-11-23T01:07:29Z [Term] id: GO:2000282 name: regulation of amino acid biosynthetic process def: "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "regulation of cellular amino acid anabolism" EXACT [GOC:obol] synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] synonym: "regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol] synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol] is_a: GO:0006521 ! regulation of amino acid metabolic process is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008652 ! regulates amino acid biosynthetic process relationship: RO:0002211 GO:0008652 ! regulates amino acid biosynthetic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI created_by: vw creation_date: 2010-12-10T11:54:19Z [Term] id: GO:2000283 name: negative regulation of amino acid biosynthetic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." [GOC:obol] synonym: "negative regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "negative regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of amino acid formation" EXACT [GOC:obol] synonym: "negative regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "negative regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045763 ! negative regulation of amino acid metabolic process is_a: GO:2000282 ! regulation of amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008652 ! negatively regulates amino acid biosynthetic process relationship: RO:0002212 GO:0008652 ! negatively regulates amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:23Z [Term] id: GO:2000284 name: positive regulation of amino acid biosynthetic process def: "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "positive regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "positive regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of amino acid formation" EXACT [GOC:obol] synonym: "positive regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "positive regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0045764 ! positive regulation of amino acid metabolic process is_a: GO:2000282 ! regulation of amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008652 ! positively regulates amino acid biosynthetic process relationship: RO:0002213 GO:0008652 ! positively regulates amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:27Z [Term] id: GO:2000287 name: positive regulation of myotome development def: "Any process that activates or increases the frequency, rate or extent of myotome development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000290 ! regulation of myotome development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061055 ! positively regulates myotome development relationship: RO:0002213 GO:0061055 ! positively regulates myotome development created_by: rl creation_date: 2010-12-16T05:17:15Z [Term] id: GO:2000288 name: positive regulation of myoblast proliferation def: "Any process that activates or increases the frequency, rate or extent of myoblast proliferation." [GOC:BHF] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051450 ! positively regulates myoblast proliferation relationship: RO:0002213 GO:0051450 ! positively regulates myoblast proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2010-12-16T05:20:52Z [Term] id: GO:2000290 name: regulation of myotome development def: "Any process that modulates the frequency, rate or extent of myotome development." [GOC:mah] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061055 ! regulates myotome development relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002211 GO:0061055 ! regulates myotome development created_by: mah creation_date: 2010-12-20T10:22:05Z [Term] id: GO:2000291 name: regulation of myoblast proliferation def: "Any process that modulates the frequency, rate or extent of myoblast proliferation." [GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0051450 ! regulates myoblast proliferation relationship: RO:0002211 GO:0051450 ! regulates myoblast proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: mah creation_date: 2010-12-20T10:34:26Z [Term] id: GO:2000292 name: regulation of defecation def: "Any process that modulates the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0044062 ! regulation of excretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0030421 ! regulates defecation relationship: RO:0002211 GO:0030421 ! regulates defecation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2010-12-21T09:23:08Z [Term] id: GO:2000293 name: negative regulation of defecation def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060457 ! negative regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0030421 ! negatively regulates defecation relationship: RO:0002212 GO:0030421 ! negatively regulates defecation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2010-12-21T09:23:13Z [Term] id: GO:2000294 name: positive regulation of defecation def: "Any process that activates or increases the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060456 ! positive regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0030421 ! positively regulates defecation relationship: RO:0002213 GO:0030421 ! positively regulates defecation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2010-12-21T09:23:16Z [Term] id: GO:2000351 name: regulation of endothelial cell apoptotic process def: "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "regulation of endothelial cell apoptosis" NARROW [] synonym: "regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072577 ! regulates endothelial cell apoptotic process relationship: RO:0002211 GO:0072577 ! regulates endothelial cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: mah creation_date: 2011-02-03T10:43:16Z [Term] id: GO:2000352 name: negative regulation of endothelial cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "negative regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of endothelial cell apoptosis" NARROW [] synonym: "negative regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072577 ! negatively regulates endothelial cell apoptotic process relationship: RO:0002212 GO:0072577 ! negatively regulates endothelial cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: mah creation_date: 2011-02-03T10:43:20Z [Term] id: GO:2000353 name: positive regulation of endothelial cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "positive regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of endothelial cell apoptosis" NARROW [] synonym: "positive regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072577 ! positively regulates endothelial cell apoptotic process relationship: RO:0002213 GO:0072577 ! positively regulates endothelial cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: mah creation_date: 2011-02-03T10:43:23Z [Term] id: GO:2000374 name: regulation of oxygen metabolic process def: "Any process that modulates the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072592 ! regulates oxygen metabolic process relationship: RO:0002211 GO:0072592 ! regulates oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:32Z [Term] id: GO:2000380 name: regulation of mesoderm development def: "Any process that modulates the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007498 ! regulates mesoderm development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0007498 ! regulates mesoderm development created_by: vk creation_date: 2011-02-15T03:09:46Z [Term] id: GO:2000381 name: negative regulation of mesoderm development def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007498 ! negatively regulates mesoderm development relationship: RO:0002212 GO:0007498 ! negatively regulates mesoderm development created_by: vk creation_date: 2011-02-15T03:10:02Z [Term] id: GO:2000382 name: positive regulation of mesoderm development def: "Any process that activates or increases the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007498 ! positively regulates mesoderm development relationship: RO:0002213 GO:0007498 ! positively regulates mesoderm development created_by: vk creation_date: 2011-02-15T03:10:12Z [Term] id: GO:2000383 name: regulation of ectoderm development def: "Any process that modulates the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0007398 ! regulates ectoderm development relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0007398 ! regulates ectoderm development created_by: vk creation_date: 2011-02-15T03:17:10Z [Term] id: GO:2000384 name: negative regulation of ectoderm development def: "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007398 ! negatively regulates ectoderm development relationship: RO:0002212 GO:0007398 ! negatively regulates ectoderm development created_by: vk creation_date: 2011-02-15T03:17:27Z [Term] id: GO:2000385 name: positive regulation of ectoderm development def: "Any process that activates or increases the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007398 ! positively regulates ectoderm development relationship: RO:0002213 GO:0007398 ! positively regulates ectoderm development created_by: vk creation_date: 2011-02-15T03:17:39Z [Term] id: GO:2000401 name: regulation of lymphocyte migration def: "Any process that modulates the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072676 ! regulates lymphocyte migration relationship: RO:0002211 GO:0072676 ! regulates lymphocyte migration created_by: mah creation_date: 2011-02-23T10:45:19Z [Term] id: GO:2000402 name: negative regulation of lymphocyte migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071676 ! negative regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072676 ! negatively regulates lymphocyte migration relationship: RO:0002212 GO:0072676 ! negatively regulates lymphocyte migration created_by: mah creation_date: 2011-02-23T10:45:47Z [Term] id: GO:2000403 name: positive regulation of lymphocyte migration def: "Any process that activates or increases the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071677 ! positive regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072676 ! positively regulates lymphocyte migration relationship: RO:0002213 GO:0072676 ! positively regulates lymphocyte migration created_by: mah creation_date: 2011-02-23T10:46:06Z [Term] id: GO:2000404 name: regulation of T cell migration def: "Any process that modulates the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "regulation of T-cell migration" EXACT [GOC:obol] synonym: "regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0072678 ! regulates T cell migration relationship: RO:0002211 GO:0072678 ! regulates T cell migration created_by: mah creation_date: 2011-02-23T10:48:24Z [Term] id: GO:2000405 name: negative regulation of T cell migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "negative regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "negative regulation of T-cell migration" EXACT [GOC:obol] synonym: "negative regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000402 ! negative regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072678 ! negatively regulates T cell migration relationship: RO:0002212 GO:0072678 ! negatively regulates T cell migration created_by: mah creation_date: 2011-02-23T10:48:52Z [Term] id: GO:2000406 name: positive regulation of T cell migration def: "Any process that activates or increases the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "positive regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "positive regulation of T-cell migration" EXACT [GOC:obol] synonym: "positive regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000403 ! positive regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072678 ! positively regulates T cell migration relationship: RO:0002213 GO:0072678 ! positively regulates T cell migration created_by: mah creation_date: 2011-02-23T10:49:12Z [Term] id: GO:2000471 name: regulation of hematopoietic stem cell migration def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035701 ! regulates hematopoietic stem cell migration relationship: RO:0002211 GO:0035701 ! regulates hematopoietic stem cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: bf creation_date: 2011-03-09T09:34:08Z [Term] id: GO:2000472 name: negative regulation of hematopoietic stem cell migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "negative regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035701 ! negatively regulates hematopoietic stem cell migration relationship: RO:0002212 GO:0035701 ! negatively regulates hematopoietic stem cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: bf creation_date: 2011-03-09T09:34:54Z [Term] id: GO:2000473 name: positive regulation of hematopoietic stem cell migration def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "positive regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035701 ! positively regulates hematopoietic stem cell migration relationship: RO:0002213 GO:0035701 ! positively regulates hematopoietic stem cell migration property_value: RO:0002161 NCBITaxon:451864 created_by: bf creation_date: 2011-03-09T09:35:25Z [Term] id: GO:2000495 name: regulation of cell proliferation involved in compound eye morphogenesis def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035736 ! regulates cell proliferation involved in compound eye morphogenesis relationship: in_taxon NCBITaxon:6656 ! Arthropoda relationship: RO:0002211 GO:0035736 ! regulates cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:18:34Z [Term] id: GO:2000496 name: negative regulation of cell proliferation involved in compound eye morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035736 ! negatively regulates cell proliferation involved in compound eye morphogenesis relationship: RO:0002212 GO:0035736 ! negatively regulates cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:19:22Z [Term] id: GO:2000497 name: positive regulation of cell proliferation involved in compound eye morphogenesis def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035736 ! positively regulates cell proliferation involved in compound eye morphogenesis relationship: RO:0002213 GO:0035736 ! positively regulates cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:19:54Z [Term] id: GO:2000542 name: negative regulation of gastrulation def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0045992 ! negative regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0007369 ! negatively regulates gastrulation relationship: RO:0002212 GO:0007369 ! negatively regulates gastrulation created_by: yaf creation_date: 2011-04-01T04:10:08Z [Term] id: GO:2000543 name: positive regulation of gastrulation def: "Any process that activates or increases the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0040019 ! positive regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0007369 ! positively regulates gastrulation relationship: RO:0002213 GO:0007369 ! positively regulates gastrulation created_by: yaf creation_date: 2011-04-01T04:10:15Z [Term] id: GO:2000547 name: regulation of dendritic cell dendrite assembly def: "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097026 ! regulates dendritic cell dendrite assembly relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0097026 ! regulates dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:21:55Z [Term] id: GO:2000548 name: negative regulation of dendritic cell dendrite assembly def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "negative regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097026 ! negatively regulates dendritic cell dendrite assembly relationship: RO:0002212 GO:0097026 ! negatively regulates dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:22:01Z [Term] id: GO:2000549 name: positive regulation of dendritic cell dendrite assembly def: "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "positive regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097026 ! positively regulates dendritic cell dendrite assembly relationship: RO:0002213 GO:0097026 ! positively regulates dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:22:06Z [Term] id: GO:2000606 name: regulation of cell proliferation involved in mesonephros development def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0061209 ! regulates cell proliferation involved in mesonephros development relationship: RO:0002211 GO:0061209 ! regulates cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:19Z [Term] id: GO:2000607 name: negative regulation of cell proliferation involved in mesonephros development def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901723 ! negative regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0061209 ! negatively regulates cell proliferation involved in mesonephros development relationship: RO:0002212 GO:0061209 ! negatively regulates cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:23Z [Term] id: GO:2000608 name: positive regulation of cell proliferation involved in mesonephros development def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0061209 ! positively regulates cell proliferation involved in mesonephros development relationship: RO:0002213 GO:0061209 ! positively regulates cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:25Z [Term] id: GO:2000647 name: negative regulation of stem cell proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0072089 ! negatively regulates stem cell proliferation relationship: RO:0002212 GO:0072089 ! negatively regulates stem cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2011-04-27T01:04:22Z [Term] id: GO:2000648 name: positive regulation of stem cell proliferation def: "Any process that activates or increases the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072089 ! positively regulates stem cell proliferation relationship: RO:0002213 GO:0072089 ! positively regulates stem cell proliferation property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4751 created_by: dph creation_date: 2011-04-27T01:04:25Z [Term] id: GO:2000649 name: regulation of sodium ion transmembrane transporter activity def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:1902305 ! regulation of sodium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0015081 ! regulates sodium ion transmembrane transporter activity relationship: RO:0002211 GO:0015081 ! regulates sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:42:53Z [Term] id: GO:2000651 name: positive regulation of sodium ion transmembrane transporter activity def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0015081 ! positively regulates sodium ion transmembrane transporter activity relationship: RO:0002213 GO:0015081 ! positively regulates sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:43:00Z [Term] id: GO:2000668 name: regulation of dendritic cell apoptotic process def: "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097048 ! regulates dendritic cell apoptotic process relationship: RO:0002211 GO:0097048 ! regulates dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:16Z [Term] id: GO:2000669 name: negative regulation of dendritic cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097048 ! negatively regulates dendritic cell apoptotic process relationship: RO:0002212 GO:0097048 ! negatively regulates dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:21Z [Term] id: GO:2000670 name: positive regulation of dendritic cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097048 ! positively regulates dendritic cell apoptotic process relationship: RO:0002213 GO:0097048 ! positively regulates dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:26Z [Term] id: GO:2000671 name: regulation of motor neuron apoptotic process def: "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097049 ! regulates motor neuron apoptotic process relationship: RO:0002211 GO:0097049 ! regulates motor neuron apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-05-09T10:56:17Z [Term] id: GO:2000672 name: negative regulation of motor neuron apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "negative regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043524 ! negative regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097049 ! negatively regulates motor neuron apoptotic process relationship: RO:0002212 GO:0097049 ! negatively regulates motor neuron apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-05-09T10:56:21Z [Term] id: GO:2000673 name: positive regulation of motor neuron apoptotic process def: "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "positive regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043525 ! positive regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097049 ! positively regulates motor neuron apoptotic process relationship: RO:0002213 GO:0097049 ! positively regulates motor neuron apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-05-09T10:56:24Z [Term] id: GO:2000674 name: regulation of type B pancreatic cell apoptotic process def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097050 ! regulates type B pancreatic cell apoptotic process relationship: RO:0002211 GO:0097050 ! regulates type B pancreatic cell apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2011-05-09T11:51:09Z [Term] id: GO:2000675 name: negative regulation of type B pancreatic cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "negative regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "negative regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097050 ! negatively regulates type B pancreatic cell apoptotic process relationship: RO:0002212 GO:0097050 ! negatively regulates type B pancreatic cell apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2011-05-09T11:51:12Z [Term] id: GO:2000676 name: positive regulation of type B pancreatic cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "positive regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "positive regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097050 ! positively regulates type B pancreatic cell apoptotic process relationship: RO:0002213 GO:0097050 ! positively regulates type B pancreatic cell apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2011-05-09T11:51:15Z [Term] id: GO:2000690 name: regulation of cardiac muscle cell myoblast differentiation def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045661 ! regulation of myoblast differentiation is_a: GO:0051890 ! regulation of cardioblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060379 ! regulates cardiac muscle cell myoblast differentiation relationship: RO:0002211 GO:0060379 ! regulates cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:01Z [Term] id: GO:2000691 name: negative regulation of cardiac muscle cell myoblast differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "negative regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "negative regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045662 ! negative regulation of myoblast differentiation is_a: GO:0051892 ! negative regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060379 ! negatively regulates cardiac muscle cell myoblast differentiation relationship: RO:0002212 GO:0060379 ! negatively regulates cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:06Z [Term] id: GO:2000696 name: regulation of epithelial cell differentiation involved in kidney development def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035850 ! regulates epithelial cell differentiation involved in kidney development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0035850 ! regulates epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:52Z [Term] id: GO:2000697 name: negative regulation of epithelial cell differentiation involved in kidney development def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035850 ! negatively regulates epithelial cell differentiation involved in kidney development relationship: RO:0002212 GO:0035850 ! negatively regulates epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:55Z [Term] id: GO:2000698 name: positive regulation of epithelial cell differentiation involved in kidney development def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035850 ! positively regulates epithelial cell differentiation involved in kidney development relationship: RO:0002213 GO:0035850 ! positively regulates epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:57Z [Term] id: GO:2000700 name: positive regulation of cardiac muscle cell myoblast differentiation def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "positive regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "positive regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045663 ! positive regulation of myoblast differentiation is_a: GO:0051891 ! positive regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060379 ! positively regulates cardiac muscle cell myoblast differentiation relationship: RO:0002213 GO:0060379 ! positively regulates cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:09Z [Term] id: GO:2000725 name: regulation of cardiac muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051153 ! regulation of striated muscle cell differentiation is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0055007 ! regulates cardiac muscle cell differentiation relationship: RO:0002211 GO:0055007 ! regulates cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:06Z [Term] id: GO:2000726 name: negative regulation of cardiac muscle cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "negative regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "negative regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0055007 ! negatively regulates cardiac muscle cell differentiation relationship: RO:0002212 GO:0055007 ! negatively regulates cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:11Z [Term] id: GO:2000727 name: positive regulation of cardiac muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "positive regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "positive regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0055007 ! positively regulates cardiac muscle cell differentiation relationship: RO:0002213 GO:0055007 ! positively regulates cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:15Z [Term] id: GO:2000729 name: positive regulation of mesenchymal cell proliferation involved in ureter development def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development." [GOC:obol] synonym: "positive regulation of ureter mesenchymal cell proliferation" RELATED [GOC:obol] synonym: "positive regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:obol] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072198 ! positively regulates mesenchymal cell proliferation involved in ureter development relationship: RO:0002213 GO:0072198 ! positively regulates mesenchymal cell proliferation involved in ureter development created_by: yaf creation_date: 2011-06-10T02:27:19Z [Term] id: GO:2000736 name: regulation of stem cell differentiation def: "Any process that modulates the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0048863 ! regulates stem cell differentiation relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0048863 ! regulates stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:16Z [Term] id: GO:2000737 name: negative regulation of stem cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0048863 ! negatively regulates stem cell differentiation relationship: RO:0002212 GO:0048863 ! negatively regulates stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:20Z [Term] id: GO:2000738 name: positive regulation of stem cell differentiation def: "Any process that activates or increases the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0048863 ! positively regulates stem cell differentiation relationship: RO:0002213 GO:0048863 ! positively regulates stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:23Z [Term] id: GO:2000765 name: regulation of cytoplasmic translation def: "Any process that modulates the frequency, rate or extent of cytoplasmic translation." [GOC:obol] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0002181 ! regulates cytoplasmic translation relationship: RO:0002211 GO:0002181 ! regulates cytoplasmic translation created_by: vw creation_date: 2011-06-20T10:39:19Z [Term] id: GO:2000766 name: negative regulation of cytoplasmic translation def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation." [GOC:obol] is_a: GO:0017148 ! negative regulation of translation is_a: GO:2000765 ! regulation of cytoplasmic translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0002181 ! negatively regulates cytoplasmic translation relationship: RO:0002212 GO:0002181 ! negatively regulates cytoplasmic translation created_by: vw creation_date: 2011-06-20T10:39:23Z [Term] id: GO:2000767 name: positive regulation of cytoplasmic translation def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic translation." [GOC:obol] is_a: GO:0045727 ! positive regulation of translation is_a: GO:2000765 ! regulation of cytoplasmic translation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0002181 ! positively regulates cytoplasmic translation relationship: RO:0002213 GO:0002181 ! positively regulates cytoplasmic translation created_by: vw creation_date: 2011-06-20T10:39:26Z [Term] id: GO:2000768 name: positive regulation of nephron tubule epithelial cell differentiation def: "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:obol] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0072160 ! positively regulates nephron tubule epithelial cell differentiation relationship: RO:0002213 GO:0072160 ! positively regulates nephron tubule epithelial cell differentiation created_by: yaf creation_date: 2011-06-22T11:55:06Z [Term] id: GO:2000790 name: regulation of mesenchymal cell proliferation involved in lung development def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060916 ! regulates mesenchymal cell proliferation involved in lung development relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0060916 ! regulates mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:50Z [Term] id: GO:2000791 name: negative regulation of mesenchymal cell proliferation involved in lung development def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060916 ! negatively regulates mesenchymal cell proliferation involved in lung development relationship: RO:0002212 GO:0060916 ! negatively regulates mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:53Z [Term] id: GO:2000792 name: positive regulation of mesenchymal cell proliferation involved in lung development def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0060916 ! positively regulates mesenchymal cell proliferation involved in lung development relationship: RO:0002213 GO:0060916 ! positively regulates mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:56Z [Term] id: GO:2000794 name: regulation of epithelial cell proliferation involved in lung morphogenesis def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0060502 ! regulates epithelial cell proliferation involved in lung morphogenesis relationship: in_taxon NCBITaxon:7776 ! Gnathostomata relationship: RO:0002211 GO:0060502 ! regulates epithelial cell proliferation involved in lung morphogenesis created_by: pr creation_date: 2011-06-25T07:22:38Z [Term] id: GO:2000795 name: negative regulation of epithelial cell proliferation involved in lung morphogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0060502 ! negatively regulates epithelial cell proliferation involved in lung morphogenesis relationship: RO:0002212 GO:0060502 ! negatively regulates epithelial cell proliferation involved in lung morphogenesis created_by: pr creation_date: 2011-06-25T07:22:42Z [Term] id: GO:2000818 name: negative regulation of myoblast proliferation def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051450 ! negatively regulates myoblast proliferation relationship: RO:0002212 GO:0051450 ! negatively regulates myoblast proliferation property_value: RO:0002161 NCBITaxon:4751 created_by: pr creation_date: 2011-07-12T03:06:04Z [Term] id: GO:2000826 name: regulation of heart morphogenesis def: "Any process that modulates the frequency, rate or extent of heart morphogenesis." [GOC:BHF] synonym: "regulation of cardiac morphogenesis" RELATED [GOC:obol] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003007 ! regulates heart morphogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: RO:0002211 GO:0003007 ! regulates heart morphogenesis created_by: vk creation_date: 2011-07-19T10:08:58Z [Term] id: GO:2000831 name: regulation of steroid hormone secretion def: "Any process that modulates the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0044060 ! regulation of endocrine process is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035929 ! regulates steroid hormone secretion relationship: RO:0002211 GO:0035929 ! regulates steroid hormone secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-26T08:38:46Z [Term] id: GO:2000832 name: negative regulation of steroid hormone secretion def: "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035929 ! negatively regulates steroid hormone secretion relationship: RO:0002212 GO:0035929 ! negatively regulates steroid hormone secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-26T08:38:50Z [Term] id: GO:2000833 name: positive regulation of steroid hormone secretion def: "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035929 ! positively regulates steroid hormone secretion relationship: RO:0002213 GO:0035929 ! positively regulates steroid hormone secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-26T08:38:51Z [Term] id: GO:2000834 name: regulation of androgen secretion def: "Any process that modulates the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035935 ! regulates androgen secretion relationship: RO:0002211 GO:0035935 ! regulates androgen secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-26T08:39:45Z [Term] id: GO:2000835 name: negative regulation of androgen secretion def: "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000832 ! negative regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035935 ! negatively regulates androgen secretion relationship: RO:0002212 GO:0035935 ! negatively regulates androgen secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-26T08:39:48Z [Term] id: GO:2000836 name: positive regulation of androgen secretion def: "Any process that activates or increases the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000833 ! positive regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035935 ! positively regulates androgen secretion relationship: RO:0002213 GO:0035935 ! positively regulates androgen secretion property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: bf creation_date: 2011-07-26T08:39:51Z [Term] id: GO:2000977 name: regulation of forebrain neuron differentiation def: "Any process that modulates the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0021879 ! regulates forebrain neuron differentiation relationship: in_taxon NCBITaxon:7711 ! Chordata relationship: RO:0002211 GO:0021879 ! regulates forebrain neuron differentiation created_by: yaf creation_date: 2011-08-03T12:09:12Z [Term] id: GO:2000978 name: negative regulation of forebrain neuron differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:2000977 ! regulation of forebrain neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0021879 ! negatively regulates forebrain neuron differentiation relationship: RO:0002212 GO:0021879 ! negatively regulates forebrain neuron differentiation created_by: yaf creation_date: 2011-08-03T12:09:16Z [Term] id: GO:2000979 name: positive regulation of forebrain neuron differentiation def: "Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] is_a: GO:0045666 ! positive regulation of neuron differentiation is_a: GO:2000977 ! regulation of forebrain neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0021879 ! positively regulates forebrain neuron differentiation relationship: RO:0002213 GO:0021879 ! positively regulates forebrain neuron differentiation created_by: yaf creation_date: 2011-08-03T12:09:19Z [Term] id: GO:2001012 name: mesenchymal cell differentiation involved in renal system development def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] synonym: "mesenchymal cell differentiation involved in urinary system development" RELATED [GOC:obol] synonym: "mesenchymal cell differentiation involved in urinary tract development" RELATED [GOC:obol] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0072001 ! renal system development relationship: part_of GO:0072001 ! renal system development created_by: yaf creation_date: 2011-08-09T04:05:14Z [Term] id: GO:2001013 name: epithelial cell proliferation involved in renal tubule morphogenesis def: "Any epithelial cell proliferation that is involved in renal tubule morphogenesis." [GOC:obol] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0061333 ! renal tubule morphogenesis relationship: in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0061333 ! renal tubule morphogenesis created_by: yaf creation_date: 2011-08-12T11:37:29Z [Term] id: GO:2001014 name: regulation of skeletal muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035914 ! regulates skeletal muscle cell differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0035914 ! regulates skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:37Z [Term] id: GO:2001015 name: negative regulation of skeletal muscle cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035914 ! negatively regulates skeletal muscle cell differentiation relationship: RO:0002212 GO:0035914 ! negatively regulates skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:41Z [Term] id: GO:2001016 name: positive regulation of skeletal muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035914 ! positively regulates skeletal muscle cell differentiation relationship: RO:0002213 GO:0035914 ! positively regulates skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:44Z [Term] id: GO:2001017 name: regulation of retrograde axon cargo transport def: "Any process that modulates the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] synonym: "regulation of retrograde axonal transport" EXACT [GOC:obol] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0008090 ! regulates retrograde axonal transport relationship: in_taxon NCBITaxon:33208 ! Metazoa relationship: RO:0002211 GO:0008090 ! regulates retrograde axonal transport created_by: kmv creation_date: 2011-08-11T09:44:42Z [Term] id: GO:2001018 name: negative regulation of retrograde axon cargo transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] synonym: "negative regulation of retrograde axonal transport" EXACT [GOC:obol] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:2001017 ! regulation of retrograde axon cargo transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0008090 ! negatively regulates retrograde axonal transport relationship: RO:0002212 GO:0008090 ! negatively regulates retrograde axonal transport created_by: kmv creation_date: 2011-08-11T09:44:46Z [Term] id: GO:2001019 name: positive regulation of retrograde axon cargo transport def: "Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] synonym: "positive regulation of retrograde axonal transport" EXACT [GOC:obol] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:2001017 ! regulation of retrograde axon cargo transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0008090 ! positively regulates retrograde axonal transport relationship: RO:0002213 GO:0008090 ! positively regulates retrograde axonal transport created_by: kmv creation_date: 2011-08-11T09:44:49Z [Term] id: GO:2001035 name: regulation of tongue muscle cell differentiation def: "Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035981 ! regulates tongue muscle cell differentiation relationship: RO:0002211 GO:0035981 ! regulates tongue muscle cell differentiation created_by: yaf creation_date: 2011-08-24T11:10:16Z [Term] id: GO:2001036 name: negative regulation of tongue muscle cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] is_a: GO:1902810 ! negative regulation of skeletal muscle fiber differentiation is_a: GO:2001035 ! regulation of tongue muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035981 ! negatively regulates tongue muscle cell differentiation relationship: RO:0002212 GO:0035981 ! negatively regulates tongue muscle cell differentiation created_by: yaf creation_date: 2011-08-24T11:10:20Z [Term] id: GO:2001037 name: positive regulation of tongue muscle cell differentiation def: "Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] is_a: GO:1902811 ! positive regulation of skeletal muscle fiber differentiation is_a: GO:2001035 ! regulation of tongue muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035981 ! positively regulates tongue muscle cell differentiation relationship: RO:0002213 GO:0035981 ! positively regulates tongue muscle cell differentiation created_by: yaf creation_date: 2011-08-24T11:10:22Z [Term] id: GO:2001049 name: regulation of tendon cell differentiation def: "Any process that modulates the frequency, rate or extent of tendon cell differentiation." [GOC:obol] synonym: "regulation of muscle attachment cell differentiation" EXACT [GOC:obol] synonym: "regulation of tenocyte differentiation" RELATED [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0035990 ! regulates tendon cell differentiation relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0035990 ! regulates tendon cell differentiation created_by: yaf creation_date: 2011-09-01T09:20:32Z [Term] id: GO:2001050 name: negative regulation of tendon cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation." [GOC:obol] synonym: "negative regulation of muscle attachment cell differentiation" EXACT [GOC:obol] synonym: "negative regulation of tenocyte differentiation" RELATED [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001049 ! regulation of tendon cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0035990 ! negatively regulates tendon cell differentiation relationship: RO:0002212 GO:0035990 ! negatively regulates tendon cell differentiation created_by: yaf creation_date: 2011-09-01T09:20:38Z [Term] id: GO:2001051 name: positive regulation of tendon cell differentiation def: "Any process that activates or increases the frequency, rate or extent of tendon cell differentiation." [GOC:obol] synonym: "positive regulation of muscle attachment cell differentiation" EXACT [GOC:obol] synonym: "positive regulation of tenocyte differentiation" RELATED [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001049 ! regulation of tendon cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0035990 ! positively regulates tendon cell differentiation relationship: RO:0002213 GO:0035990 ! positively regulates tendon cell differentiation created_by: yaf creation_date: 2011-09-01T09:20:42Z [Term] id: GO:2001053 name: regulation of mesenchymal cell apoptotic process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097152 ! regulates mesenchymal cell apoptotic process relationship: RO:0002211 GO:0097152 ! regulates mesenchymal cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: yaf creation_date: 2011-09-08T02:49:59Z [Term] id: GO:2001054 name: negative regulation of mesenchymal cell apoptotic process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097152 ! negatively regulates mesenchymal cell apoptotic process relationship: RO:0002212 GO:0097152 ! negatively regulates mesenchymal cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: yaf creation_date: 2011-09-08T02:50:05Z [Term] id: GO:2001055 name: positive regulation of mesenchymal cell apoptotic process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097152 ! positively regulates mesenchymal cell apoptotic process relationship: RO:0002213 GO:0097152 ! positively regulates mesenchymal cell apoptotic process property_value: RO:0002161 NCBITaxon:4896 created_by: yaf creation_date: 2011-09-08T02:50:09Z [Term] id: GO:2001141 name: regulation of RNA biosynthetic process def: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] synonym: "regulation of RNA anabolism" EXACT [GOC:obol] synonym: "regulation of RNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of RNA formation" EXACT [GOC:obol] synonym: "regulation of RNA synthesis" EXACT [GOC:obol] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0032774 ! regulates RNA biosynthetic process relationship: RO:0002211 GO:0032774 ! regulates RNA biosynthetic process created_by: dph creation_date: 2011-10-17T11:36:25Z [Term] id: GO:2001151 name: regulation of renal water transport def: "Any process that modulates the frequency, rate or extent of renal water transport." [GOC:obol] is_a: GO:0050878 ! regulation of body fluid levels is_a: GO:0051049 ! regulation of transport is_a: GO:0098801 ! regulation of renal system process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0003097 ! regulates renal water transport relationship: RO:0002211 GO:0003097 ! regulates renal water transport property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: yaf creation_date: 2011-10-24T11:37:51Z [Term] id: GO:2001152 name: negative regulation of renal water transport def: "Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport." [GOC:obol] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2001151 ! regulation of renal water transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0003097 ! negatively regulates renal water transport relationship: RO:0002212 GO:0003097 ! negatively regulates renal water transport property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: yaf creation_date: 2011-10-24T11:37:57Z [Term] id: GO:2001153 name: positive regulation of renal water transport def: "Any process that activates or increases the frequency, rate or extent of renal water transport." [GOC:obol] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2001151 ! regulation of renal water transport intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0003097 ! positively regulates renal water transport relationship: RO:0002213 GO:0003097 ! positively regulates renal water transport property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: yaf creation_date: 2011-10-24T11:38:01Z [Term] id: GO:2001198 name: regulation of dendritic cell differentiation def: "Any process that modulates the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097028 ! regulates dendritic cell differentiation relationship: RO:0002211 GO:0097028 ! regulates dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:27Z [Term] id: GO:2001199 name: negative regulation of dendritic cell differentiation def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902106 ! negative regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097028 ! negatively regulates dendritic cell differentiation relationship: RO:0002212 GO:0097028 ! negatively regulates dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:33Z [Term] id: GO:2001200 name: positive regulation of dendritic cell differentiation def: "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902107 ! positive regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097028 ! positively regulates dendritic cell differentiation relationship: RO:0002213 GO:0097028 ! positively regulates dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:36Z [Term] id: GO:2001212 name: regulation of vasculogenesis def: "Any process that modulates the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001570 ! regulates vasculogenesis relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: RO:0002211 GO:0001570 ! regulates vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:31Z [Term] id: GO:2001213 name: negative regulation of vasculogenesis def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "negative regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001570 ! negatively regulates vasculogenesis relationship: RO:0002212 GO:0001570 ! negatively regulates vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:36Z [Term] id: GO:2001214 name: positive regulation of vasculogenesis def: "Any process that activates or increases the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "positive regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001570 ! positively regulates vasculogenesis relationship: RO:0002213 GO:0001570 ! positively regulates vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:39Z [Term] id: GO:2001222 name: regulation of neuron migration def: "Any process that modulates the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "regulation of neuron guidance" RELATED [GOC:obol] synonym: "regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0001764 ! regulates neuron migration relationship: in_taxon NCBITaxon:6072 ! Eumetazoa relationship: RO:0002211 GO:0001764 ! regulates neuron migration created_by: kmv creation_date: 2011-11-17T10:01:38Z [Term] id: GO:2001223 name: negative regulation of neuron migration def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "negative regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "negative regulation of neuron guidance" RELATED [GOC:obol] synonym: "negative regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0001764 ! negatively regulates neuron migration relationship: RO:0002212 GO:0001764 ! negatively regulates neuron migration created_by: kmv creation_date: 2011-11-17T10:01:45Z [Term] id: GO:2001224 name: positive regulation of neuron migration def: "Any process that activates or increases the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "positive regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "positive regulation of neuron guidance" RELATED [GOC:obol] synonym: "positive regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0001764 ! positively regulates neuron migration relationship: RO:0002213 GO:0001764 ! positively regulates neuron migration created_by: kmv creation_date: 2011-11-17T10:01:49Z [Term] id: GO:2001233 name: regulation of apoptotic signaling pathway def: "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002211 GO:0097190 ! regulates apoptotic signaling pathway relationship: RO:0002211 GO:0097190 ! regulates apoptotic signaling pathway property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-11-24T01:20:49Z [Term] id: GO:2001234 name: negative regulation of apoptotic signaling pathway def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "negative regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0097190 ! negatively regulates apoptotic signaling pathway relationship: RO:0002212 GO:0097190 ! negatively regulates apoptotic signaling pathway property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-11-24T01:20:54Z [Term] id: GO:2001235 name: positive regulation of apoptotic signaling pathway def: "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "positive regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0097190 ! positively regulates apoptotic signaling pathway relationship: RO:0002213 GO:0097190 ! positively regulates apoptotic signaling pathway property_value: RO:0002161 NCBITaxon:4896 created_by: pr creation_date: 2011-11-24T01:20:58Z [Term] id: GO:2001251 name: negative regulation of chromosome organization def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "negative regulation of chromosome organisation" EXACT [GOC:obol] synonym: "negative regulation of chromosome organization and biogenesis" RELATED [GOC:obol] synonym: "negative regulation of maintenance of genome integrity" RELATED [GOC:obol] synonym: "negative regulation of nuclear genome maintenance" RELATED [GOC:obol] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002212 GO:0051276 ! negatively regulates chromosome organization relationship: RO:0002212 GO:0051276 ! negatively regulates chromosome organization created_by: yaf creation_date: 2011-12-02T02:01:20Z [Term] id: GO:2001252 name: positive regulation of chromosome organization def: "Any process that activates or increases the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "positive regulation of chromosome organisation" EXACT [GOC:obol] synonym: "positive regulation of chromosome organization and biogenesis" RELATED [GOC:obol] synonym: "positive regulation of maintenance of genome integrity" RELATED [GOC:obol] synonym: "positive regulation of nuclear genome maintenance" RELATED [GOC:obol] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: RO:0002213 GO:0051276 ! positively regulates chromosome organization relationship: RO:0002213 GO:0051276 ! positively regulates chromosome organization created_by: yaf creation_date: 2011-12-02T02:01:26Z [Term] id: IAO:0000003 name: measurement unit label def: "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure." [] is_a: IAO:0000009 ! datum label property_value: IAO:0000111 "measurement unit label" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000005 name: objective specification def: "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved." [] is_a: IAO:0000033 ! directive information entity property_value: editor_note "2009-03-16: original definition when imported from OBI read: \"objective is an non realizable information entity which can serve as that proper part of a plan towards which the realization of the plan is directed.\"" xsd:string property_value: editor_note "2014-03-31: In the example of usage (\"In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction\") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that." xsd:string property_value: editor_note "Answers the question, why did you do this experiment?" xsd:string property_value: IAO:0000111 "objective specification" xsd:string property_value: IAO:0000112 "In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Barry Smith" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Jennifer Fostel" xsd:string property_value: IAO:0000118 "goal specification" xsd:string property_value: IAO:0000119 "OBI Plan and Planned Process/Roles Branch" xsd:string property_value: IAO:0000119 "OBI_0000217" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000007 name: action specification def: "A directive information entity that describes an action the bearer will take." [] is_a: IAO:0000033 ! directive information entity property_value: IAO:0000112 "Pour the contents of flask 1 into flask 2" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "OBI Plan and Planned Process branch" xsd:string [Term] id: IAO:0000009 name: datum label def: "A label is a symbol that is part of some other datum and is used to either partially define the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label" [] is_a: IAO:0000030 ! information content entity property_value: IAO:0000111 "datum label" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000010 name: software def: "Software is a plan specification composed of a series of instructions that can be \ninterpreted by or directly executed by a processing unit." [] is_a: IAO:0000104 ! plan specification property_value: IAO:0000111 "software" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000027 name: data item def: "a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." [] def: "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." [] is_a: IAO:0000030 ! information content entity property_value: editor_note "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers." xsd:string property_value: editor_note "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum." xsd:string property_value: editor_note "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym." xsd:string property_value: editor_note "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/" xsd:string property_value: editor_note "JAR: datum -- well, this will be very tricky to define, but maybe some \ninformation-like stuff that might be put into a computer and that is \nmeant, by someone, to denote and/or to be interpreted by some \nprocess... I would include lists, tables, sentences... I think I might \ndefer to Barry, or to Brian Cantwell Smith\n\nJAR: A data item is an approximately justified approximately true approximate belief" xsd:string property_value: IAO:0000111 "data item" xsd:string property_value: IAO:0000112 "Data items include counts of things, analyte concentrations, and statistical summaries." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string property_value: IAO:0000117 "PERSON: Jonathan Rees" xsd:string property_value: IAO:0000118 "data" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl property_value: IAO:0000412 http://purl.obolibrary.org/obo/ogms.owl [Term] id: IAO:0000030 name: information content entity def: "A generically dependent continuant that is about some thing." [] is_a: BFO:0000031 ! generically dependent continuant relationship: IAO:0000136 BFO:0000001 ! is about entity property_value: editor_note "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)." xsd:string property_value: editor_note "information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).\n\nPrevious. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity." xsd:string property_value: editor_note "Pier: 'data, information or knowledge'. OR 'representation'" xsd:string property_value: IAO:0000111 "information content entity" xsd:string property_value: IAO:0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string property_value: IAO:0000119 "OBI_0000142" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl property_value: IAO:0000412 http://purl.obolibrary.org/obo/ogms.owl [Term] id: IAO:0000033 name: directive information entity def: "An information content entity whose concretizations indicate to their bearer how to realize them in a process." [] is_a: IAO:0000030 ! information content entity relationship: IAO:0000136 BFO:0000017 ! is about realizable entity property_value: editor_note "2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was \"is the specification of a process that can be concretized and realized by an actor\" with alternative term \"instruction\".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term." xsd:string property_value: editor_note "2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it." xsd:string property_value: editor_note "8/6/2009 Alan Ruttenberg: Changed label from \"information entity about a realizable\" after discussions at ICBO" xsd:string property_value: editor_note "Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan" xsd:string property_value: IAO:0000111 "directive information entity" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000037 name: dot plot def: "A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions." [] is_a: IAO:0000038 ! graph property_value: IAO:0000111 "dot plot" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000038 name: graph def: "A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way." [] is_a: IAO:0000308 ! figure property_value: IAO:0000111 "graph" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000064 name: algorithm def: "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata." [] is_a: IAO:0000104 ! plan specification property_value: IAO:0000111 "algorithm" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000078 name: curation status specification def: "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: editor_note "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)" xsd:string property_value: IAO:0000111 "curation status specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON:Bill Bug" xsd:string property_value: IAO:0000119 "GROUP:OBI:" xsd:string property_value: IAO:0000119 "OBI_0000266" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000098 name: data format specification def: "A data format specification is the information content borne by the document published defining the specification.\nExample: The ISO document specifying what encompasses an XML document; The instructions in a XSD file" [] is_a: IAO:0000033 ! directive information entity property_value: IAO:0000111 "data format specification" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000100 name: data set def: "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets." [] is_a: IAO:0000027 ! data item property_value: IAO:0000111 "data set" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000101 name: image def: "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface." [] is_a: IAO:0000308 ! figure property_value: IAO:0000111 "image" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000102 name: data about an ontology part def: "Data about an ontology part is a data item about a part of an ontology, for example a term" [] def: "data about an ontology part is a data item about a part of an ontology, for example a term" [] is_a: IAO:0000027 ! data item property_value: IAO:0000111 "data about an ontology part" xsd:string property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string [Term] id: IAO:0000104 name: plan specification def: "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified." [] def: "A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified." [] comment: 2/3/2009 Comment from OBI review.\n\nAction specification not well enough specified.\nConditional specification not well enough specified.\nQuestion whether all plan specifications have objective specifications.\n\nRequest that IAO either clarify these or change definitions not to use them is_a: IAO:0000033 ! directive information entity relationship: has_part IAO:0000005 ! objective specification relationship: has_part IAO:0000007 ! action specification property_value: editor_note "2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was \" a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan\". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term." xsd:string property_value: editor_note "2014-03-31: A plan specification can have other parts, such as conditional specifications." xsd:string property_value: editor_note "Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved" xsd:string property_value: IAO:0000111 "plan specification" xsd:string property_value: IAO:0000112 "PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "OBI Plan and Planned Process branch" xsd:string property_value: IAO:0000119 "OBI_0000344" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000109 name: measurement datum def: "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device." [] is_a: IAO:0000027 ! data item relationship: OBI:0001938 OBI:0001933 ! has value specification value specification property_value: editor_note "2/2/2009 is_specified_output of some assay?" xsd:string property_value: IAO:0000111 "measurement datum" xsd:string property_value: IAO:0000112 "Examples of measurement data are the recoding of the weight of a mouse as {40,mass,\"grams\"}, the recording of an observation of the behavior of the mouse {,process,\"agitated\"}, the recording of the expression level of a gene as measured through the process of microarray experiment {3.4,luminosity,}." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "person:Chris Stoeckert" xsd:string property_value: IAO:0000119 "group:OBI" xsd:string property_value: IAO:0000119 "OBI_0000305" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000178 name: material information bearer def: "A material entity in which a concretization of an information content entity inheres." [] is_a: BFO:0000040 ! material entity property_value: IAO:0000111 "material information bearer" xsd:string property_value: IAO:0000112 "a brain" xsd:string property_value: IAO:0000112 "a hard drive" xsd:string property_value: IAO:0000112 "A page of a paperback novel with writing on it. The paper itself is a material information bearer, the pattern of ink is the information carrier." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "GROUP: IAO" xsd:string [Term] id: IAO:0000179 name: histogram def: "A histogram is a report graph which is a statistical description of a\ndistribution in terms of occurrence frequencies of different event classes." [] is_a: IAO:0000038 ! graph property_value: IAO:0000111 "histogram" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000180 name: heatmap def: "A heatmap is a report graph which is a graphical representation of data\nwhere the values taken by a variable(s) are shown as colors in a\ntwo-dimensional map." [] is_a: IAO:0000038 ! graph property_value: IAO:0000111 "heatmap" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000183 name: dendrogram def: "A dendrogram is a report graph which is a tree diagram\nfrequently used to illustrate the arrangement of the clusters produced by a\nclustering algorithm." [] is_a: IAO:0000038 ! graph property_value: IAO:0000111 "dendrogram" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000184 name: scatter plot def: "A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis." [] is_a: IAO:0000038 ! graph property_value: IAO:0000111 "scatter plot" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000225 name: obsolescence reason specification def: "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: editor_note "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology." xsd:string property_value: IAO:0000111 "obsolescence reason specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string [Term] id: IAO:0000308 name: figure def: "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something." [] is_a: IAO:0000030 ! information content entity property_value: IAO:0000111 "figure" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000310 name: document def: "A collection of information content entities intended to be understood together as a whole" [] is_a: IAO:0000030 ! information content entity property_value: IAO:0000111 "document" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/iao.owl [Term] id: IAO:0000409 name: denotator type def: "A denotator type indicates how a term should be interpreted from an ontological perspective." [] is_a: IAO:0000102 ! data about an ontology part property_value: IAO:0000111 "denotator type" xsd:string property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string [Term] id: NBO:0000001 name: body part movement def: "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]" [] synonym: "stationary movement" EXACT [] is_a: NBO:0000338 ! kinesthetic behavior created_by: George Gkoutos [Term] id: NBO:0000007 name: mouth movement def: "The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC]" [] synonym: "mouth part movement" NARROW [] synonym: "other moved mouth parts" NARROW [] is_a: NBO:0000001 ! body part movement created_by: George Gkoutos [Term] id: NBO:0000073 name: chewing def: "The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]" [] synonym: "chew" EXACT [] synonym: "gnaw" EXACT [] synonym: "mastication" EXACT [] is_a: NBO:0000747 ! jaw movement created_by: George Gkoutos [Term] id: NBO:0000313 name: behavior process alt_id: NBO:0000000 def: "\"The action, reaction, or performance of an organism in response to external or internal stimuli.\" [GO:GO\\:0007610]" [] synonym: "behavior" EXACT [] synonym: "behaviour" EXACT [] is_a: GO:0007610 ! behavior created_by: George Gkoutos [Term] id: NBO:0000338 name: kinesthetic behavior def: "\"Movement behavior of the body or its parts.\"" [] is_a: NBO:0000313 ! behavior process created_by: George Gkoutos [Term] id: NBO:0000747 name: jaw movement is_a: NBO:0000007 ! mouth movement created_by: gkoutos [Term] id: NBO:0001786 name: regulation of behavior def: "\"Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.\" [GO:0050795]" [] is_a: NBO:0000313 ! behavior process relationship: RO:0002211 NBO:0000313 ! regulates behavior process created_by: George Gkoutos [Term] id: NCBITaxon:1 name: root namespace: ncbi_taxonomy synonym: "all" RELATED synonym [] xref: GC_ID:1 xref: PMID:30365038 xref: PMID:32761142 [Term] id: NCBITaxon:10066 name: Muridae xref: GC_ID:1 xref: PMID:15371245 is_a: NCBITaxon:337687 ! Muroidea [Term] id: NCBITaxon:10088 name: Mus synonym: "mice" EXACT genbank_common_name [] synonym: "mouse" EXACT OMO:0003003 [] synonym: "Mus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae disjoint_from: NCBITaxon:10114 ! Rattus [Term] id: NCBITaxon:10090 name: Mus musculus alt_id: NCBITaxon:85055 synonym: "house mouse" EXACT genbank_common_name [] synonym: "mouse" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:862507 ! Mus [Term] id: NCBITaxon:10114 name: Rattus synonym: "rat" EXACT OMO:0003003 [] synonym: "rats" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae [Term] id: NCBITaxon:10239 name: Viruses is_a: OBI:0100026 ! organism property_value: IAO:0000111 "Viruses" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:105389 name: Sedentaria synonym: "Palpata" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6341 ! Polychaeta [Term] id: NCBITaxon:105391 name: Canalipalpata xref: GC_ID:1 is_a: NCBITaxon:105389 ! Sedentaria [Term] id: NCBITaxon:110814 name: Xenoturbellida xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha disjoint_from: NCBITaxon:147099 ! Acoelomorpha [Term] id: NCBITaxon:110815 name: Xenoturbella xref: GC_ID:1 is_a: NCBITaxon:1547233 ! Xenoturbellidae [Term] id: NCBITaxon:117565 name: Myxini synonym: "Agnatha" RELATED in_part [] synonym: "Hyperotreti" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1476529 ! Cyclostomata disjoint_from: NCBITaxon:117569 ! Hyperoartia [Term] id: NCBITaxon:117569 name: Hyperoartia synonym: "Agnatha" RELATED in_part [] synonym: "Cephalaspidomorphi" RELATED in_part [] synonym: "lampreys" EXACT genbank_common_name [] synonym: "Monorhina" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:1476529 ! Cyclostomata [Term] id: NCBITaxon:117570 name: Teleostomi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata disjoint_from: NCBITaxon:7777 ! Chondrichthyes property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:117571 name: Euteleostomi namespace: ncbi_taxonomy alt_id: NCBITaxon:40673 synonym: "bony vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi property_value: has_rank NCBITaxon:clade property_value: IAO:0000111 "Euteleostomi" xsd:string property_value: IAO:0000118 "bony vertebrates" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:118072 name: Coelacanthimorpha synonym: "Actinistia" RELATED synonym [] synonym: "Choanichthyes" RELATED in_part [] synonym: "Crossopterygii" RELATED in_part [] synonym: "lobe-finned fishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8287 ! Sarcopterygii disjoint_from: NCBITaxon:1338369 ! Dipnotetrapodomorpha [Term] id: NCBITaxon:119089 name: Chromadorea alt_id: NCBITaxon:27837 synonym: "Adenophorea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6231 ! Nematoda [Term] id: NCBITaxon:1206794 name: Ecdysozoa xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia disjoint_from: NCBITaxon:2697495 ! Spiralia [Term] id: NCBITaxon:1206795 name: Lophotrochozoa xref: GC_ID:1 is_a: NCBITaxon:2697495 ! Spiralia [Term] id: NCBITaxon:123365 name: Neoteleostei xref: GC_ID:1 is_a: NCBITaxon:1489388 ! Euteleosteomorpha [Term] id: NCBITaxon:123366 name: Eurypterygia synonym: "Eurypterygii" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123365 ! Neoteleostei [Term] id: NCBITaxon:123367 name: Ctenosquamata xref: GC_ID:1 is_a: NCBITaxon:123366 ! Eurypterygia [Term] id: NCBITaxon:123368 name: Acanthomorphata synonym: "Acanthomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123367 ! Ctenosquamata [Term] id: NCBITaxon:123369 name: Euacanthomorphacea synonym: "Euacanthomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123368 ! Acanthomorphata [Term] id: NCBITaxon:124129 name: Acipenserinae xref: GC_ID:1 is_a: NCBITaxon:7900 ! Acipenseridae [Term] id: NCBITaxon:124130 name: Acipenserini xref: GC_ID:1 is_a: NCBITaxon:124129 ! Acipenserinae [Term] id: NCBITaxon:1312402 name: Xenacoelomorpha xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria disjoint_from: NCBITaxon:33317 ! Protostomia disjoint_from: NCBITaxon:33511 ! Deuterostomia [Term] id: NCBITaxon:131567 name: cellular organisms namespace: ncbi_taxonomy synonym: "biota" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1 ! root property_value: has_rank http://purl.obolibrary.org/obo/NCBITaxon_cellular_root property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:9000002 [Term] id: NCBITaxon:1329799 name: Archelosauria synonym: "Archosauria-Testudines" RELATED synonym [] synonym: "Testudines + Archosauria group" RELATED synonym [] xref: GC_ID:1 xref: PMID:22839753 xref: PMID:25450099 is_a: NCBITaxon:32561 ! Sauria disjoint_from: NCBITaxon:8504 ! Lepidosauria [Term] id: NCBITaxon:1329911 name: Toxicofera xref: GC_ID:1 xref: PMID:16286089 xref: PMID:19281946 xref: PMID:22982760 is_a: NCBITaxon:1329912 ! Episquamata [Term] id: NCBITaxon:1329912 name: Episquamata xref: GC_ID:1 xref: PMID:16286089 xref: PMID:22982760 is_a: NCBITaxon:1329950 ! Unidentata [Term] id: NCBITaxon:1329950 name: Unidentata xref: GC_ID:1 xref: PMID:22982760 is_a: NCBITaxon:1329961 ! Bifurcata [Term] id: NCBITaxon:1329961 name: Bifurcata synonym: "split-tongued squamates" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:22982760 is_a: NCBITaxon:8509 ! Squamata [Term] id: NCBITaxon:1338369 name: Dipnotetrapodomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8287 ! Sarcopterygii property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:1437010 name: Boreoeutheria namespace: ncbi_taxonomy synonym: "Boreotheria" RELATED synonym [] xref: GC_ID:1 xref: PMID:11743200 xref: PMID:11791233 is_a: NCBITaxon:9347 ! Eutheria disjoint_from: NCBITaxon:311790 ! Afrotheria disjoint_from: NCBITaxon:9348 ! Xenarthra property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:147099 name: Acoelomorpha xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha [Term] id: NCBITaxon:1476529 name: Cyclostomata synonym: "Agnatha" RELATED synonym [] synonym: "jawless vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata disjoint_from: NCBITaxon:7776 ! Gnathostomata [Term] id: NCBITaxon:1489340 name: Elopocephalai xref: GC_ID:1 is_a: NCBITaxon:32443 ! Teleostei disjoint_from: NCBITaxon:1489341 ! Osteoglossocephalai [Term] id: NCBITaxon:1489341 name: Osteoglossocephalai xref: GC_ID:1 is_a: NCBITaxon:32443 ! Teleostei [Term] id: NCBITaxon:1489388 name: Euteleosteomorpha xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala disjoint_from: NCBITaxon:186634 ! Otomorpha [Term] id: NCBITaxon:1489872 name: Percomorphaceae xref: GC_ID:1 is_a: NCBITaxon:123369 ! Euacanthomorphacea [Term] id: NCBITaxon:1489922 name: Eupercaria synonym: "Percomorpharia" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1489872 ! Percomorphaceae [Term] id: NCBITaxon:1547233 name: Xenoturbellidae xref: GC_ID:1 is_a: NCBITaxon:110814 ! Xenoturbellida [Term] id: NCBITaxon:182222 name: Muraeninae xref: GC_ID:1 is_a: NCBITaxon:46660 ! Muraenidae [Term] id: NCBITaxon:186622 name: Acipenseroidei xref: GC_ID:1 is_a: NCBITaxon:7899 ! Acipenseriformes [Term] id: NCBITaxon:186623 name: Actinopteri xref: GC_ID:1 is_a: NCBITaxon:7898 ! Actinopterygii [Term] id: NCBITaxon:186624 name: Elopocephala xref: GC_ID:1 is_a: NCBITaxon:1489340 ! Elopocephalai [Term] id: NCBITaxon:186625 name: Clupeocephala xref: GC_ID:1 is_a: NCBITaxon:1489341 ! Osteoglossocephalai [Term] id: NCBITaxon:186626 name: Otophysi synonym: "Otophysa" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:32519 ! Ostariophysi [Term] id: NCBITaxon:186627 name: Cypriniphysae synonym: "Cypriniphysi" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186626 ! Otophysi [Term] id: NCBITaxon:186634 name: Otomorpha synonym: "Ostarioclupeomorpha" RELATED synonym [] synonym: "Otocephala" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala [Term] id: NCBITaxon:189497 name: Echidna xref: GC_ID:1 is_a: NCBITaxon:182222 ! Muraeninae [Term] id: NCBITaxon:1963758 name: Myomorpha synonym: "mice and others" EXACT genbank_common_name [] synonym: "Sciurognathi" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:9989 ! Rodentia [Term] id: NCBITaxon:197562 name: Pancrustacea xref: GC_ID:1 xref: PMID:10874751 xref: PMID:11557979 is_a: NCBITaxon:197563 ! Mandibulata [Term] id: NCBITaxon:197563 name: Mandibulata synonym: "mandibulates" EXACT OMO:0003003 [] xref: GC_ID:1 xref: PMID:11557979 xref: PMID:9727836 is_a: NCBITaxon:6656 ! Arthropoda [Term] id: NCBITaxon:2 name: Bacteria is_a: OBI:0100026 ! organism property_value: IAO:0000111 "Bacteria" xsd:string property_value: IAO:0000118 "eubacteria" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:207598 name: Homininae synonym: "Homo/Pan/Gorilla group" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:9604 ! Hominidae [Term] id: NCBITaxon:2157 name: Archaea is_a: OBI:0100026 ! organism property_value: IAO:0000111 "Archaea" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:2301116 name: Rhabditina xref: GC_ID:1 is_a: NCBITaxon:6236 ! Rhabditida [Term] id: NCBITaxon:2301119 name: Rhabditomorpha xref: GC_ID:1 is_a: NCBITaxon:2301116 ! Rhabditina [Term] id: NCBITaxon:262014 name: Xenopus synonym: "Xenopus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:8353 ! Xenopus [Term] id: NCBITaxon:2653789 name: Whippomorpha xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla disjoint_from: NCBITaxon:35497 ! Suina disjoint_from: NCBITaxon:9834 ! Tylopoda disjoint_from: NCBITaxon:9845 ! Ruminantia [Term] id: NCBITaxon:2697495 name: Spiralia xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia [Term] id: NCBITaxon:2743709 name: Danionidae xref: GC_ID:1 is_a: NCBITaxon:30727 ! Cyprinoidei [Term] id: NCBITaxon:2743711 name: Danioninae xref: GC_ID:1 is_a: NCBITaxon:2743709 ! Danionidae [Term] id: NCBITaxon:2759 name: Eukaryota namespace: ncbi_taxonomy synonym: "Eucarya" RELATED synonym [] synonym: "Eucaryotae" RELATED synonym [] synonym: "eucaryotes" EXACT genbank_common_name [] synonym: "Eukarya" RELATED synonym [] synonym: "Eukaryotae" RELATED synonym [] synonym: "eukaryotes" EXACT genbank_common_name [] synonym: "eukaryotes" EXACT common_name [] synonym: "eukaryotes" RELATED blast_name [] xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: COB:0000022 ! organism is_a: NCBITaxon:131567 ! cellular organisms is_a: OBI:0100026 ! organism property_value: has_rank NCBITaxon:domain property_value: has_rank NCBITaxon:superkingdom property_value: IAO:0000111 "Eukaryota" xsd:string property_value: IAO:0000118 "eucaryotes" xsd:string property_value: IAO:0000118 "eukaryotes" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0000037 [Term] id: NCBITaxon:27592 name: Bovinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9895 ! Bovidae property_value: has_rank NCBITaxon:subfamily property_value: TAXRANK:1000000 TAXRANK:0000024 [Term] id: NCBITaxon:2841271 name: Testudinata xref: GC_ID:1 is_a: NCBITaxon:1329799 ! Archelosauria disjoint_from: NCBITaxon:8492 ! Archosauria [Term] id: NCBITaxon:30319 name: Pipoidea xref: GC_ID:1 is_a: NCBITaxon:8342 ! Anura [Term] id: NCBITaxon:30727 name: Cyprinoidei synonym: "Cyprinoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7952 ! Cypriniformes [Term] id: NCBITaxon:3072905 name: Pinnipedia synonym: "pinnipeds" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379584 ! Caniformia disjoint_from: NCBITaxon:9608 ! Canidae [Term] id: NCBITaxon:3073799 name: Columbimorphae synonym: "pigeons, sandgrouse & allies" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:3078114 ! Neoaves [Term] id: NCBITaxon:3078114 name: Neoaves xref: GC_ID:1 is_a: NCBITaxon:8825 ! Neognathae [Term] id: NCBITaxon:31022 name: Tetraodontiformes synonym: "pufferfishes and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1489922 ! Eupercaria [Term] id: NCBITaxon:31028 name: Tetraodontoidei xref: GC_ID:1 is_a: NCBITaxon:31022 ! Tetraodontiformes [Term] id: NCBITaxon:31031 name: Tetraodontidae synonym: "puffer fishes" EXACT OMO:0003003 [] synonym: "puffers" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32517 ! Tetradontoidea [Term] id: NCBITaxon:31032 name: Takifugu synonym: "Fugu" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:31031 ! Tetraodontidae [Term] id: NCBITaxon:31033 name: Takifugu rubripes synonym: "Fugu rubripes" RELATED synonym [] synonym: "Sphaeroides rubripes" RELATED synonym [] synonym: "Tetraodon rubripes" RELATED synonym [] synonym: "tiger puffer" EXACT OMO:0003003 [] synonym: "torafugu" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:31032 ! Takifugu [Term] id: NCBITaxon:311790 name: Afrotheria xref: GC_ID:1 xref: PMID:11114173 xref: PMID:11214319 xref: PMID:12128031 xref: PMID:12878460 xref: PMID:15306319 xref: PMID:9214502 xref: PMID:9667998 is_a: NCBITaxon:9347 ! Eutheria disjoint_from: NCBITaxon:9348 ! Xenarthra [Term] id: NCBITaxon:314145 name: Laurasiatheria namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11214318 xref: PMID:11214319 xref: PMID:12878460 is_a: NCBITaxon:1437010 ! Boreoeutheria disjoint_from: NCBITaxon:314146 ! Euarchontoglires property_value: has_rank NCBITaxon:superorder property_value: TAXRANK:1000000 TAXRANK:0000020 [Term] id: NCBITaxon:314146 name: Euarchontoglires namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:12878460 xref: PMID:15522813 is_a: NCBITaxon:1437010 ! Boreoeutheria property_value: has_rank NCBITaxon:superorder property_value: IAO:0000111 "Euarchontoglires" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0000020 [Term] id: NCBITaxon:314147 name: Glires namespace: ncbi_taxonomy synonym: "Rodents and rabbits" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:15522813 is_a: NCBITaxon:314146 ! Euarchontoglires disjoint_from: NCBITaxon:9443 ! Primates property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:314293 name: Simiiformes synonym: "Anthropoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:376913 ! Haplorrhini [Term] id: NCBITaxon:314295 name: Hominoidea synonym: "ape" EXACT OMO:0003003 [] synonym: "apes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9526 ! Catarrhini [Term] id: NCBITaxon:32341 name: Sophophora xref: GC_ID:1 is_a: NCBITaxon:7215 ! Drosophila [Term] id: NCBITaxon:32346 name: melanogaster group xref: GC_ID:1 is_a: NCBITaxon:32341 ! Sophophora [Term] id: NCBITaxon:32351 name: melanogaster subgroup xref: GC_ID:1 is_a: NCBITaxon:32346 ! melanogaster group [Term] id: NCBITaxon:32440 name: Chondrostei xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri disjoint_from: NCBITaxon:41665 ! Neopterygii [Term] id: NCBITaxon:32443 name: Teleostei synonym: "teleost fishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:41665 ! Neopterygii [Term] id: NCBITaxon:32517 name: Tetradontoidea xref: GC_ID:1 is_a: NCBITaxon:31028 ! Tetraodontoidei [Term] id: NCBITaxon:32519 name: Ostariophysi xref: GC_ID:1 is_a: NCBITaxon:186634 ! Otomorpha [Term] id: NCBITaxon:32521 name: Elopomorpha xref: GC_ID:1 is_a: NCBITaxon:186624 ! Elopocephala [Term] id: NCBITaxon:32523 name: Tetrapoda namespace: ncbi_taxonomy synonym: "tetrapods" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha disjoint_from: NCBITaxon:7878 ! Dipnomorpha property_value: has_rank NCBITaxon:clade property_value: IAO:0000111 "Tetrapoda" xsd:string property_value: IAO:0000118 "tetrapods" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:32524 name: Amniota namespace: ncbi_taxonomy synonym: "amniotes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda disjoint_from: NCBITaxon:8292 ! Amphibia property_value: has_rank NCBITaxon:clade property_value: IAO:0000111 "Amniota" xsd:string property_value: IAO:0000118 "amniotes" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:32525 name: Theria namespace: ncbi_taxonomy synonym: "Theria" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia disjoint_from: NCBITaxon:9254 ! Prototheria property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:32561 name: Sauria namespace: ncbi_taxonomy synonym: "Diapsida" RELATED synonym [] synonym: "diapsids" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8457 ! Sauropsida property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:33090 name: Viridiplantae synonym: "Chlorobionta" RELATED synonym [] synonym: "Chlorophyta/Embryophyta group" EXACT equivalent_name [] synonym: "chlorophyte/embryophyte group" EXACT equivalent_name [] synonym: "Chloroplastida" RELATED synonym [] synonym: "green plants" EXACT OMO:0003003 [] synonym: "green plants" RELATED blast_name [] xref: GC_ID:1 xref: PMID:16248873 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota disjoint_from: NCBITaxon:33154 ! Opisthokonta [Term] id: NCBITaxon:33154 name: Opisthokonta namespace: ncbi_taxonomy synonym: "Fungi/Metazoa group" RELATED synonym [] synonym: "opisthokonts" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:clade property_value: IAO:0000111 "Opisthokonta" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:33208 name: Metazoa namespace: ncbi_taxonomy synonym: "Animalia" RELATED synonym [] synonym: "animals" EXACT genbank_common_name [] synonym: "animals" RELATED blast_name [] synonym: "metazoans" EXACT OMO:0003003 [] synonym: "metazoans" EXACT genbank_common_name [] synonym: "multicellular animals" EXACT OMO:0003003 [] synonym: "multicellular animals" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:4751 ! Fungi property_value: has_rank NCBITaxon:kingdom property_value: IAO:0000111 "Metazoa" xsd:string property_value: IAO:0000118 "metazoans" xsd:string property_value: IAO:0000118 "multicellular animals" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0000017 [Term] id: NCBITaxon:33213 name: Bilateria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa disjoint_from: NCBITaxon:6073 ! Cnidaria property_value: has_rank NCBITaxon:clade property_value: IAO:0000111 "Bilateria" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:33317 name: Protostomia xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria disjoint_from: NCBITaxon:33511 ! Deuterostomia [Term] id: NCBITaxon:33340 name: Neoptera xref: GC_ID:1 is_a: NCBITaxon:7496 ! Pterygota [Term] id: NCBITaxon:33392 name: Endopterygota synonym: "Holometabola" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:33340 ! Neoptera [Term] id: NCBITaxon:33511 name: Deuterostomia namespace: ncbi_taxonomy synonym: "deuterostomes" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:33554 name: Carnivora namespace: ncbi_taxonomy synonym: "carnivores" EXACT genbank_common_name [] synonym: "carnivores" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314145 ! Laurasiatheria disjoint_from: NCBITaxon:91561 ! Artiodactyla disjoint_from: NCBITaxon:9787 ! Perissodactyla property_value: has_rank NCBITaxon:order property_value: TAXRANK:1000000 TAXRANK:0000003 [Term] id: NCBITaxon:337687 name: Muroidea xref: GC_ID:1 xref: PMID:15019624 xref: PMID:15371245 is_a: NCBITaxon:1963758 ! Myomorpha [Term] id: NCBITaxon:338152 name: Felinae namespace: ncbi_taxonomy alt_id: NCBITaxon:338151 synonym: "Acinonychinae" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:9681 ! Felidae property_value: has_rank NCBITaxon:subfamily property_value: TAXRANK:1000000 TAXRANK:0000024 [Term] id: NCBITaxon:34878 name: Cervinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9850 ! Cervidae property_value: has_rank NCBITaxon:subfamily property_value: TAXRANK:1000000 TAXRANK:0000024 [Term] id: NCBITaxon:35497 name: Suina namespace: ncbi_taxonomy synonym: "Suiformes" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla disjoint_from: NCBITaxon:9834 ! Tylopoda disjoint_from: NCBITaxon:9845 ! Ruminantia property_value: has_rank NCBITaxon:suborder property_value: TAXRANK:1000000 TAXRANK:0000014 [Term] id: NCBITaxon:35500 name: Pecora namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9845 ! Ruminantia property_value: has_rank NCBITaxon:infraorder property_value: TAXRANK:1000000 TAXRANK:0000013 [Term] id: NCBITaxon:376913 name: Haplorrhini xref: GC_ID:1 is_a: NCBITaxon:9443 ! Primates [Term] id: NCBITaxon:379583 name: Feliformia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33554 ! Carnivora property_value: has_rank NCBITaxon:suborder property_value: TAXRANK:1000000 TAXRANK:0000014 [Term] id: NCBITaxon:379584 name: Caniformia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33554 ! Carnivora property_value: has_rank NCBITaxon:suborder property_value: TAXRANK:1000000 TAXRANK:0000014 [Term] id: NCBITaxon:39107 name: Murinae alt_id: NCBITaxon:109679 xref: GC_ID:1 is_a: NCBITaxon:10066 ! Muridae [Term] id: NCBITaxon:40674 name: Mammalia namespace: ncbi_taxonomy synonym: "mammals" EXACT genbank_common_name [] synonym: "mammals" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota disjoint_from: NCBITaxon:8457 ! Sauropsida property_value: has_rank NCBITaxon:class property_value: IAO:0000111 "Mammalia" xsd:string property_value: IAO:0000118 "mammals" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0000002 [Term] id: NCBITaxon:41324 name: Siboglinidae alt_id: NCBITaxon:167797 alt_id: NCBITaxon:27906 alt_id: NCBITaxon:29174 alt_id: NCBITaxon:41329 alt_id: NCBITaxon:54122 alt_id: NCBITaxon:55674 alt_id: NCBITaxon:55678 alt_id: NCBITaxon:6422 synonym: "Frenulata" RELATED synonym [] synonym: "Lamellibrachiidae" RELATED synonym [] synonym: "Obturata" RELATED synonym [] synonym: "Oligobrachiidae" RELATED synonym [] synonym: "Perviata" RELATED synonym [] synonym: "Pogonophora" RELATED synonym [] synonym: "pogonophores" EXACT OMO:0003003 [] synonym: "Polybrachiidae" RELATED synonym [] synonym: "Sclerolinidae" RELATED synonym [] synonym: "tube worms" EXACT genbank_common_name [] synonym: "tube worms" RELATED blast_name [] synonym: "Vestimentifera" RELATED synonym [] synonym: "vestimentiferans" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:6362 ! Sabellida [Term] id: NCBITaxon:41665 name: Neopterygii synonym: "Neopterygi" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri [Term] id: NCBITaxon:41666 name: Batrachia xref: GC_ID:1 is_a: NCBITaxon:8292 ! Amphibia [Term] id: NCBITaxon:436486 name: Dinosauria synonym: "dinosaurs" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:8492 ! Archosauria [Term] id: NCBITaxon:436489 name: Saurischia xref: GC_ID:1 is_a: NCBITaxon:436486 ! Dinosauria [Term] id: NCBITaxon:436491 name: Theropoda xref: GC_ID:1 is_a: NCBITaxon:436489 ! Saurischia [Term] id: NCBITaxon:436492 name: Coelurosauria xref: GC_ID:1 is_a: NCBITaxon:436491 ! Theropoda [Term] id: NCBITaxon:43733 name: Muscomorpha alt_id: NCBITaxon:43732 synonym: "Asilomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7203 ! Brachycera [Term] id: NCBITaxon:43738 name: Schizophora xref: GC_ID:1 is_a: NCBITaxon:480117 ! Cyclorrhapha [Term] id: NCBITaxon:43741 name: Acalyptratae xref: GC_ID:1 is_a: NCBITaxon:43738 ! Schizophora [Term] id: NCBITaxon:43746 name: Ephydroidea xref: GC_ID:1 is_a: NCBITaxon:43741 ! Acalyptratae [Term] id: NCBITaxon:43845 name: Drosophilinae xref: GC_ID:1 is_a: NCBITaxon:7214 ! Drosophilidae [Term] id: NCBITaxon:46660 name: Muraenidae synonym: "moray eels" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7933 ! Anguilliformes [Term] id: NCBITaxon:46877 name: Drosophilini xref: GC_ID:1 is_a: NCBITaxon:43845 ! Drosophilinae [Term] id: NCBITaxon:4751 name: Fungi synonym: "fungi" RELATED blast_name [] synonym: "Mycota" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:12684019 is_a: NCBITaxon:33154 ! Opisthokonta [Term] id: NCBITaxon:480117 name: Cyclorrhapha xref: GC_ID:1 is_a: NCBITaxon:480118 ! Eremoneura [Term] id: NCBITaxon:480118 name: Eremoneura xref: GC_ID:1 is_a: NCBITaxon:43733 ! Muscomorpha [Term] id: NCBITaxon:50557 name: Insecta synonym: "insects" EXACT genbank_common_name [] synonym: "insects" RELATED blast_name [] synonym: "true insects" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:6960 ! Hexapoda [Term] id: NCBITaxon:55879 name: Rhabditoidea xref: GC_ID:1 is_a: NCBITaxon:2301119 ! Rhabditomorpha [Term] id: NCBITaxon:55885 name: Peloderinae xref: GC_ID:1 is_a: NCBITaxon:6243 ! Rhabditidae [Term] id: NCBITaxon:6040 name: Porifera synonym: "Parazoa" RELATED synonym [] synonym: "sponges" EXACT genbank_common_name [] synonym: "sponges" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa disjoint_from: NCBITaxon:6072 ! Eumetazoa [Term] id: NCBITaxon:6072 name: Eumetazoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:6073 name: Cnidaria synonym: "cnidarians" EXACT genbank_common_name [] synonym: "cnidarians" RELATED blast_name [] synonym: "Coelenterata" RELATED in_part [] synonym: "coelenterates" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa [Term] id: NCBITaxon:6157 name: Platyhelminthes synonym: "flatworm" EXACT OMO:0003003 [] synonym: "flatworms" EXACT genbank_common_name [] synonym: "flatworms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa disjoint_from: NCBITaxon:6340 ! Annelida [Term] id: NCBITaxon:6231 name: Nematoda synonym: "Nemata" RELATED synonym [] synonym: "nematode" EXACT OMO:0003003 [] synonym: "nematodes" EXACT genbank_common_name [] synonym: "nematodes" RELATED blast_name [] synonym: "roundworm" EXACT OMO:0003003 [] synonym: "roundworms" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa disjoint_from: NCBITaxon:88770 ! Panarthropoda [Term] id: NCBITaxon:6236 name: Rhabditida alt_id: NCBITaxon:33251 alt_id: NCBITaxon:6308 synonym: "Strongylida" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:119089 ! Chromadorea [Term] id: NCBITaxon:6237 name: Caenorhabditis xref: GC_ID:1 is_a: NCBITaxon:55885 ! Peloderinae [Term] id: NCBITaxon:6239 name: Caenorhabditis elegans synonym: "Rhabditis elegans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6237 ! Caenorhabditis [Term] id: NCBITaxon:6243 name: Rhabditidae alt_id: NCBITaxon:54603 xref: GC_ID:1 is_a: NCBITaxon:55879 ! Rhabditoidea [Term] id: NCBITaxon:6340 name: Annelida synonym: "annelid worms" EXACT OMO:0003003 [] synonym: "segmented worms" EXACT genbank_common_name [] synonym: "segmented worms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa [Term] id: NCBITaxon:6341 name: Polychaeta synonym: "polychaetes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:6340 ! Annelida [Term] id: NCBITaxon:6362 name: Sabellida xref: GC_ID:1 is_a: NCBITaxon:105391 ! Canalipalpata [Term] id: NCBITaxon:6656 name: Arthropoda synonym: "arthropods" EXACT genbank_common_name [] synonym: "arthropods" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:88770 ! Panarthropoda [Term] id: NCBITaxon:6960 name: Hexapoda synonym: "Atelocerata" RELATED in_part [] synonym: "hexapods" EXACT genbank_common_name [] synonym: "hexapods" RELATED blast_name [] synonym: "Tracheata" RELATED in_part [] synonym: "Uniramia" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:197562 ! Pancrustacea [Term] id: NCBITaxon:7147 name: Diptera synonym: "flies" EXACT genbank_common_name [] synonym: "flies" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33392 ! Endopterygota [Term] id: NCBITaxon:7203 name: Brachycera xref: GC_ID:1 is_a: NCBITaxon:7147 ! Diptera [Term] id: NCBITaxon:7214 name: Drosophilidae synonym: "pomace flies" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:43746 ! Ephydroidea [Term] id: NCBITaxon:7215 name: Drosophila alt_id: NCBITaxon:7326 synonym: "Drosophila" EXACT scientific_name [] synonym: "fruit flies" EXACT genbank_common_name [] synonym: "fruit fly" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:46877 ! Drosophilini [Term] id: NCBITaxon:7227 name: Drosophila melanogaster alt_id: NCBITaxon:2267365 synonym: "fruit fly" EXACT genbank_common_name [] synonym: "Sophophora melanogaster" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:32351 ! melanogaster subgroup [Term] id: NCBITaxon:7496 name: Pterygota synonym: "Pterygota" EXACT scientific_name [] synonym: "winged insects" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:85512 ! Dicondylia [Term] id: NCBITaxon:7586 name: Echinodermata synonym: "echinoderms" EXACT genbank_common_name [] synonym: "echinoderms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33511 ! Deuterostomia disjoint_from: NCBITaxon:7711 ! Chordata [Term] id: NCBITaxon:7711 name: Chordata namespace: ncbi_taxonomy synonym: "chordates" EXACT genbank_common_name [] synonym: "chordates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33511 ! Deuterostomia property_value: has_rank NCBITaxon:phylum property_value: TAXRANK:1000000 TAXRANK:0000001 [Term] id: NCBITaxon:7712 name: Tunicata synonym: "tunicates" EXACT genbank_common_name [] synonym: "tunicates" RELATED blast_name [] synonym: "Urochordata" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata disjoint_from: NCBITaxon:89593 ! Craniata [Term] id: NCBITaxon:7742 name: Vertebrata namespace: ncbi_taxonomy synonym: "Vertebrata" EXACT scientific_name [] synonym: "vertebrates" EXACT genbank_common_name [] synonym: "vertebrates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:89593 ! Craniata property_value: has_rank NCBITaxon:clade property_value: IAO:0000111 "Vertebrata " xsd:string property_value: IAO:0000118 "Vertebrata" xsd:string property_value: IAO:0000118 "vertebrates" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:7745 name: Petromyzontiformes synonym: "lampreys" EXACT genbank_common_name [] synonym: "lampreys" RELATED blast_name [] synonym: "Petromyzoniformes" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:117569 ! Hyperoartia [Term] id: NCBITaxon:7761 name: Myxiniformes synonym: "hagfishes" EXACT genbank_common_name [] synonym: "hagfishes" RELATED blast_name [] synonym: "Myxinoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:117565 ! Myxini [Term] id: NCBITaxon:7762 name: Myxinidae synonym: "hagfishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7761 ! Myxiniformes [Term] id: NCBITaxon:7776 name: Gnathostomata namespace: ncbi_taxonomy synonym: "Gnathostomata" EXACT scientific_name [] synonym: "jawed vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:7777 name: Chondrichthyes synonym: "cartilaginous fishes" EXACT genbank_common_name [] synonym: "cartilaginous fishes" RELATED blast_name [] synonym: "fish" EXACT OMO:0003003 [] synonym: "fishes" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata [Term] id: NCBITaxon:7778 name: Elasmobranchii synonym: "elasmobranchs" EXACT OMO:0003003 [] synonym: "sharks & rays" EXACT genbank_common_name [] synonym: "sharks & rays" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:7777 ! Chondrichthyes disjoint_from: NCBITaxon:7863 ! Holocephali [Term] id: NCBITaxon:7863 name: Holocephali xref: GC_ID:1 is_a: NCBITaxon:7777 ! Chondrichthyes [Term] id: NCBITaxon:7864 name: Chimaeriformes synonym: "chimaeras" EXACT genbank_common_name [] synonym: "chimaeras" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:7863 ! Holocephali [Term] id: NCBITaxon:7878 name: Dipnomorpha synonym: "Choanichthyes" RELATED in_part [] synonym: "Dipneusti" RELATED synonym [] synonym: "dipnoans" EXACT OMO:0003003 [] synonym: "Dipnoi" RELATED synonym [] synonym: "fish" EXACT OMO:0003003 [] synonym: "fishes" EXACT OMO:0003003 [] synonym: "lungfishes" EXACT genbank_common_name [] synonym: "lungfishes" RELATED blast_name [] synonym: "Osteichthyes" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha [Term] id: NCBITaxon:7898 name: Actinopterygii synonym: "Actinopterygi" RELATED synonym [] synonym: "bony fishes" RELATED blast_name [] synonym: "fish" EXACT OMO:0003003 [] synonym: "fishes" EXACT OMO:0003003 [] synonym: "Osteichthyes" RELATED in_part [] synonym: "ray-finned fishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi disjoint_from: NCBITaxon:8287 ! Sarcopterygii [Term] id: NCBITaxon:7899 name: Acipenseriformes synonym: "sturgeons and paddlefish" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32440 ! Chondrostei [Term] id: NCBITaxon:7900 name: Acipenseridae synonym: "sturgeons" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:186622 ! Acipenseroidei [Term] id: NCBITaxon:7901 name: Acipenser xref: GC_ID:1 is_a: NCBITaxon:124130 ! Acipenserini [Term] id: NCBITaxon:7933 name: Anguilliformes alt_id: NCBITaxon:30678 synonym: "true eels" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32521 ! Elopomorpha [Term] id: NCBITaxon:7952 name: Cypriniformes synonym: "carps and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:186627 ! Cypriniphysae [Term] id: NCBITaxon:7954 name: Danio alt_id: NCBITaxon:46777 alt_id: NCBITaxon:487617 synonym: "Brachydanio" RELATED synonym [] synonym: "Celestichthys" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2743711 ! Danioninae [Term] id: NCBITaxon:7955 name: Danio rerio alt_id: NCBITaxon:27702 alt_id: NCBITaxon:37966 synonym: "Brachydanio rerio" RELATED synonym [] synonym: "Brachydanio rerio frankei" RELATED synonym [] synonym: "Cyprinus rerio" RELATED synonym [] synonym: "Danio frankei" RELATED synonym [] synonym: "Danio rerio frankei" RELATED synonym [] synonym: "leopard danio" EXACT OMO:0003003 [] synonym: "zebra danio" EXACT OMO:0003003 [] synonym: "zebra fish" EXACT OMO:0003003 [] synonym: "zebrafish" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7954 ! Danio [Term] id: NCBITaxon:8287 name: Sarcopterygii namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi property_value: has_rank NCBITaxon:superclass property_value: TAXRANK:1000000 TAXRANK:0000015 [Term] id: NCBITaxon:8292 name: Amphibia namespace: ncbi_taxonomy synonym: "amphibians" EXACT genbank_common_name [] synonym: "amphibians" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda property_value: has_rank NCBITaxon:class property_value: TAXRANK:1000000 TAXRANK:0000002 [Term] id: NCBITaxon:8342 name: Anura synonym: "anurans" EXACT OMO:0003003 [] synonym: "frogs" EXACT OMO:0003003 [] synonym: "frogs & toads" EXACT genbank_common_name [] synonym: "frogs & toads" RELATED blast_name [] synonym: "Salientia" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:41666 ! Batrachia [Term] id: NCBITaxon:8352 name: Pipidae synonym: "pipid frogs" EXACT OMO:0003003 [] synonym: "tongueless frogs" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:30319 ! Pipoidea [Term] id: NCBITaxon:8353 name: Xenopus synonym: "Xenopus" EXACT scientific_name [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8360 ! Xenopodinae [Term] id: NCBITaxon:8355 name: Xenopus laevis synonym: "African clawed frog" EXACT genbank_common_name [] synonym: "Bufo laevis" RELATED synonym [] synonym: "clawed frog" EXACT OMO:0003003 [] synonym: "common platanna" EXACT OMO:0003003 [] synonym: "platanna" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:262014 ! Xenopus [Term] id: NCBITaxon:8360 name: Xenopodinae synonym: "Siluraninae" RELATED synonym [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8352 ! Pipidae [Term] id: NCBITaxon:8457 name: Sauropsida namespace: ncbi_taxonomy synonym: "sauropsids" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:8459 name: Testudines synonym: "anapsid reptiles" EXACT OMO:0003003 [] synonym: "Anapsida" RELATED synonym [] synonym: "reptiles" RELATED in_part [] synonym: "Reptilia" RELATED in_part [] synonym: "turtles" EXACT genbank_common_name [] synonym: "turtles" RELATED blast_name [] xref: GC_ID:1 xref: PMID:22839753 xref: PMID:25450099 is_a: NCBITaxon:2841271 ! Testudinata [Term] id: NCBITaxon:8492 name: Archosauria xref: GC_ID:1 is_a: NCBITaxon:1329799 ! Archelosauria [Term] id: NCBITaxon:8504 name: Lepidosauria namespace: ncbi_taxonomy synonym: "lepidosaurs" EXACT OMO:0003003 [] synonym: "lizards & snakes" EXACT genbank_common_name [] synonym: "lizards & snakes" RELATED blast_name [] synonym: "reptiles" RELATED in_part [] synonym: "Reptilia" RELATED in_part [] xref: GC_ID:1 xref: PMID:22982760 is_a: NCBITaxon:32561 ! Sauria property_value: has_rank NCBITaxon:class property_value: TAXRANK:1000000 TAXRANK:0000002 [Term] id: NCBITaxon:8505 name: Sphenodontia synonym: "beaked reptiles" EXACT genbank_common_name [] synonym: "Rhynchocephalia" RELATED synonym [] synonym: "rhynchocephalians" EXACT OMO:0003003 [] synonym: "Rhynchosauria" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:8504 ! Lepidosauria disjoint_from: NCBITaxon:8509 ! Squamata [Term] id: NCBITaxon:8506 name: Sphenodontidae xref: GC_ID:1 is_a: NCBITaxon:8505 ! Sphenodontia [Term] id: NCBITaxon:8507 name: Sphenodon xref: GC_ID:1 is_a: NCBITaxon:8506 ! Sphenodontidae [Term] id: NCBITaxon:8509 name: Squamata synonym: "squamates" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:16286089 xref: PMID:22982760 xref: PMID:23627680 is_a: NCBITaxon:8504 ! Lepidosauria [Term] id: NCBITaxon:85512 name: Dicondylia xref: GC_ID:1 is_a: NCBITaxon:50557 ! Insecta [Term] id: NCBITaxon:8570 name: Serpentes synonym: "Ophidia" RELATED synonym [] synonym: "snakes" EXACT genbank_common_name [] synonym: "snakes" RELATED blast_name [] xref: GC_ID:1 xref: PMID:19281946 is_a: NCBITaxon:1329911 ! Toxicofera [Term] id: NCBITaxon:862507 name: Mus synonym: "Mus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:10088 ! Mus [Term] id: NCBITaxon:8782 name: Aves synonym: "avian" RELATED synonym [] synonym: "birds" EXACT genbank_common_name [] synonym: "birds" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:436492 ! Coelurosauria [Term] id: NCBITaxon:8783 name: Palaeognathae xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves disjoint_from: NCBITaxon:8825 ! Neognathae [Term] id: NCBITaxon:8798 name: Struthioniformes synonym: "ostriches" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8783 ! Palaeognathae [Term] id: NCBITaxon:8799 name: Struthionidae xref: GC_ID:1 is_a: NCBITaxon:8798 ! Struthioniformes [Term] id: NCBITaxon:8800 name: Struthio xref: GC_ID:1 is_a: NCBITaxon:8799 ! Struthionidae [Term] id: NCBITaxon:8801 name: Struthio camelus synonym: "African ostrich" EXACT genbank_common_name [] synonym: "ostrich" EXACT OMO:0003003 [] synonym: "Struthio camelus domesticus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:8800 ! Struthio [Term] id: NCBITaxon:8825 name: Neognathae xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves [Term] id: NCBITaxon:88770 name: Panarthropoda xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa [Term] id: NCBITaxon:8929 name: Columbiformes synonym: "pigeons and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:3073799 ! Columbimorphae [Term] id: NCBITaxon:8930 name: Columbidae synonym: "pigeons" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8929 ! Columbiformes [Term] id: NCBITaxon:89593 name: Craniata namespace: ncbi_taxonomy synonym: "Craniata" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata property_value: has_rank NCBITaxon:subphylum property_value: TAXRANK:1000000 TAXRANK:0000008 [Term] id: NCBITaxon:91561 name: Artiodactyla namespace: ncbi_taxonomy synonym: "Cetartiodactyla" RELATED synonym [] synonym: "even-toed ungulates & whales" EXACT genbank_common_name [] synonym: "even-toed ungulates & whales" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314145 ! Laurasiatheria disjoint_from: NCBITaxon:9787 ! Perissodactyla property_value: has_rank NCBITaxon:order property_value: TAXRANK:1000000 TAXRANK:0000003 [Term] id: NCBITaxon:9254 name: Prototheria xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia [Term] id: NCBITaxon:9255 name: Monotremata synonym: "egg-laying mammals" EXACT OMO:0003003 [] synonym: "monotremes" EXACT genbank_common_name [] synonym: "monotremes" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:9254 ! Prototheria [Term] id: NCBITaxon:9256 name: Ornithorhynchidae xref: GC_ID:1 is_a: NCBITaxon:9255 ! Monotremata disjoint_from: NCBITaxon:9259 ! Tachyglossidae [Term] id: NCBITaxon:9257 name: Ornithorhynchus xref: GC_ID:1 is_a: NCBITaxon:9256 ! Ornithorhynchidae [Term] id: NCBITaxon:9259 name: Tachyglossidae synonym: "echidnas" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9255 ! Monotremata [Term] id: NCBITaxon:9263 name: Metatheria synonym: "Marsupialia" RELATED synonym [] synonym: "marsupials" EXACT genbank_common_name [] synonym: "marsupials" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32525 ! Theria disjoint_from: NCBITaxon:9347 ! Eutheria [Term] id: NCBITaxon:9347 name: Eutheria namespace: ncbi_taxonomy synonym: "eutherian mammals" EXACT OMO:0003003 [] synonym: "placental mammals" EXACT OMO:0003003 [] synonym: "Placentalia" RELATED synonym [] synonym: "placentals" EXACT genbank_common_name [] synonym: "placentals" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32525 ! Theria property_value: has_rank NCBITaxon:clade property_value: TAXRANK:1000000 TAXRANK:0001004 [Term] id: NCBITaxon:9348 name: Xenarthra synonym: "armadillos and others" EXACT genbank_common_name [] synonym: "Edentata" RELATED in_part [] xref: GC_ID:1 xref: PMID:11214319 is_a: NCBITaxon:9347 ! Eutheria [Term] id: NCBITaxon:9359 name: Dasypodidae synonym: "armadillo" EXACT OMO:0003003 [] synonym: "armadillos" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:948951 ! Cingulata [Term] id: NCBITaxon:9443 name: Primates synonym: "Primata" RELATED synonym [] synonym: "primate" EXACT equivalent_name [] synonym: "primates" EXACT genbank_common_name [] synonym: "primates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314146 ! Euarchontoglires [Term] id: NCBITaxon:948951 name: Cingulata xref: GC_ID:1 is_a: NCBITaxon:9348 ! Xenarthra [Term] id: NCBITaxon:9526 name: Catarrhini xref: GC_ID:1 is_a: NCBITaxon:314293 ! Simiiformes [Term] id: NCBITaxon:9596 name: Pan alt_id: NCBITaxon:317028 alt_id: NCBITaxon:445518 synonym: "chimpanzees" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:207598 ! Homininae disjoint_from: NCBITaxon:9605 ! Homo [Term] id: NCBITaxon:9604 name: Hominidae synonym: "great apes" EXACT genbank_common_name [] synonym: "Pongidae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:314295 ! Hominoidea [Term] id: NCBITaxon:9605 name: Homo synonym: "humans" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:207598 ! Homininae [Term] id: NCBITaxon:9606 name: Homo sapiens synonym: "human" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9605 ! Homo property_value: IAO:0000111 "Homo sapiens" xsd:string property_value: IAO:0000118 "human" xsd:string property_value: IAO:0000118 "human being" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:9608 name: Canidae namespace: ncbi_taxonomy synonym: "dog, coyote, wolf, fox" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379584 ! Caniformia property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9611 name: Canis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9608 ! Canidae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9632 name: Ursidae namespace: ncbi_taxonomy synonym: "bears" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379584 ! Caniformia property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9639 name: Ursus namespace: ncbi_taxonomy alt_id: NCBITaxon:29068 xref: GC_ID:1 is_a: NCBITaxon:9632 ! Ursidae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9681 name: Felidae namespace: ncbi_taxonomy synonym: "cat family" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379583 ! Feliformia property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9682 name: Felis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:338152 ! Felinae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9709 name: Phocidae synonym: "crawling seals" EXACT OMO:0003003 [] synonym: "earless seals" EXACT OMO:0003003 [] synonym: "seal" EXACT OMO:0003003 [] synonym: "seals" EXACT OMO:0003003 [] synonym: "true seals" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:3072905 ! Pinnipedia [Term] id: NCBITaxon:9721 name: Cetacea synonym: "cetaceans" EXACT OMO:0003003 [] synonym: "whale" EXACT OMO:0003003 [] synonym: "whales" EXACT OMO:0003003 [] synonym: "whales & dolphins" EXACT genbank_common_name [] synonym: "whales & dolphins" RELATED blast_name [] synonym: "whales, dolphins & porpoises" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:2653789 ! Whippomorpha [Term] id: NCBITaxon:9761 name: Mysticeti synonym: "baleen whales" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9721 ! Cetacea [Term] id: NCBITaxon:9787 name: Perissodactyla namespace: ncbi_taxonomy synonym: "odd-toed ungulates" EXACT genbank_common_name [] synonym: "odd-toed ungulates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314145 ! Laurasiatheria property_value: has_rank NCBITaxon:order property_value: TAXRANK:1000000 TAXRANK:0000003 [Term] id: NCBITaxon:9788 name: Equidae namespace: ncbi_taxonomy synonym: "horses" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9787 ! Perissodactyla property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9789 name: Equus namespace: ncbi_taxonomy alt_id: NCBITaxon:1225530 alt_id: NCBITaxon:35506 alt_id: NCBITaxon:35507 alt_id: NCBITaxon:35508 alt_id: NCBITaxon:35509 alt_id: NCBITaxon:35510 alt_id: NCBITaxon:475184 synonym: "Amerhippus" RELATED synonym [] synonym: "Asinus" RELATED synonym [] synonym: "Dolichohippus" RELATED synonym [] synonym: "Equus subg. Amerhippus" RELATED synonym [] synonym: "Equus subg. Asinus" RELATED synonym [] synonym: "Equus subg. Dolichohippus" RELATED synonym [] synonym: "Equus subg. Equus" RELATED synonym [] synonym: "Equus subg. Hemionus" RELATED synonym [] synonym: "Equus subg. Hippotigris" RELATED synonym [] synonym: "Equus subgen. Sussemionus" RELATED synonym [] synonym: "Hemionus" RELATED synonym [] synonym: "Hippotigris" RELATED synonym [] synonym: "Sussemionus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:9788 ! Equidae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9815 name: Tubulidentata synonym: "aardvarks" EXACT genbank_common_name [] synonym: "Edentata" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:311790 ! Afrotheria [Term] id: NCBITaxon:9816 name: Orycteropodidae synonym: "aardvark" EXACT genbank_common_name [] synonym: "aardvarks" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:9815 ! Tubulidentata [Term] id: NCBITaxon:9821 name: Suidae namespace: ncbi_taxonomy alt_id: NCBITaxon:39423 synonym: "boars" EXACT OMO:0003003 [] synonym: "pigs" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:35497 ! Suina property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9822 name: Sus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9821 ! Suidae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9834 name: Tylopoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla disjoint_from: NCBITaxon:9845 ! Ruminantia property_value: has_rank NCBITaxon:suborder property_value: TAXRANK:1000000 TAXRANK:0000014 [Term] id: NCBITaxon:9835 name: Camelidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9834 ! Tylopoda property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9836 name: Camelus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9835 ! Camelidae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9845 name: Ruminantia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla property_value: has_rank NCBITaxon:suborder property_value: TAXRANK:1000000 TAXRANK:0000014 [Term] id: NCBITaxon:9850 name: Cervidae namespace: ncbi_taxonomy synonym: "deer" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:35500 ! Pecora property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9859 name: Cervus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:34878 ! Cervinae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9895 name: Bovidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:35500 ! Pecora property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9903 name: Bos namespace: ncbi_taxonomy synonym: "cattle" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:27592 ! Bovinae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9922 name: Capra namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9963 ! Caprinae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9935 name: Ovis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9963 ! Caprinae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9963 name: Caprinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9895 ! Bovidae property_value: has_rank NCBITaxon:subfamily property_value: TAXRANK:1000000 TAXRANK:0000024 [Term] id: NCBITaxon:9975 name: Lagomorpha namespace: ncbi_taxonomy synonym: "rabbits & hares" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314147 ! Glires disjoint_from: NCBITaxon:9989 ! Rodentia property_value: has_rank NCBITaxon:order property_value: TAXRANK:1000000 TAXRANK:0000003 [Term] id: NCBITaxon:9979 name: Leporidae namespace: ncbi_taxonomy synonym: "rabbits and hares" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9975 ! Lagomorpha property_value: has_rank NCBITaxon:family property_value: TAXRANK:1000000 TAXRANK:0000004 [Term] id: NCBITaxon:9980 name: Lepus namespace: ncbi_taxonomy synonym: "hares" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9979 ! Leporidae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9984 name: Oryctolagus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9979 ! Leporidae property_value: has_rank NCBITaxon:genus property_value: TAXRANK:1000000 TAXRANK:0000005 [Term] id: NCBITaxon:9989 name: Rodentia synonym: "rodent" EXACT OMO:0003003 [] synonym: "rodents" EXACT genbank_common_name [] synonym: "rodents" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314147 ! Glires [Term] id: OBA:0000001 name: biological attribute namespace: oba is_a: PATO:0000001 ! quality [Term] id: OBA:0000015 name: anatomical structure size namespace: oba def: "The size of a anatomical structure." [AUTO:patterns/patterns/entity_attribute] synonym: "size of anatomical structure" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:2045412 ! anatomical entity morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000061 ! inheres in anatomical structure relationship: RO:0000052 UBERON:0000061 ! inheres in anatomical structure [Term] id: OBA:0002007 name: reproductive system size def: "The size of a reproductive system." [AUTO:patterns/patterns/entity_attribute] synonym: "size of reproductive system" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0002160 ! reproductive system morphology trait is_a: OBA:VT0005389 ! reproductive system trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000990 ! inheres in reproductive system [Term] id: OBA:0002017 name: gonad size def: "The size of a gonad." [AUTO:patterns/patterns/entity_attribute] synonym: "size of gonad" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0002160 ! reproductive system morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000991 ! inheres in gonad relationship: RO:0000052 UBERON:0000991 ! inheres in gonad [Term] id: OBA:0002019 name: uterus position def: "The position of a uterus." [AUTO:patterns/patterns/entity_attribute] synonym: "position of uterus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000213 ! female reproductive system quality is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0000995 ! inheres in uterus relationship: RO:0000052 UBERON:0000995 ! inheres in uterus [Term] id: OBA:0002024 name: mouth size def: "The size of a mouth." [AUTO:patterns/patterns/entity_attribute] synonym: "size of mouth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000452 ! mouth morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000165 ! inheres in mouth relationship: RO:0000052 UBERON:0000165 ! inheres in mouth [Term] id: OBA:0002033 name: secondary palate size def: "The size of a secondary palate." [AUTO:patterns/patterns/entity_attribute] synonym: "size of secondary palate" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0003755 ! palate morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001716 ! inheres in secondary palate relationship: RO:0000052 UBERON:0001716 ! inheres in secondary palate [Term] id: OBA:0002043 name: secondary palate height def: "The height of a secondary palate." [AUTO:patterns/patterns/entity_attribute] synonym: "height of secondary palate" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002033 ! secondary palate size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0001716 ! inheres in secondary palate [Term] id: OBA:0002055 name: face size def: "The size of a face." [AUTO:patterns/patterns/entity_attribute] synonym: "size of face" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0003743 ! facial morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001456 ! inheres in face relationship: RO:0000052 UBERON:0001456 ! inheres in face [Term] id: OBA:0002056 name: face length def: "The length of a face." [AUTO:patterns/patterns/entity_attribute] synonym: "length of face" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002055 ! face size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001456 ! inheres in face [Term] id: OBA:0002074 name: ear position def: "The position of a ear." [AUTO:patterns/patterns/entity_attribute] synonym: "position of ear" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005382 ! head trait is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0001690 ! inheres in ear relationship: RO:0000052 UBERON:0001690 ! inheres in ear [Term] id: OBA:0002077 name: external ear position def: "The position of a external ear." [AUTO:patterns/patterns/entity_attribute] synonym: "position of external ear" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005382 ! head trait is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0001691 ! inheres in external ear relationship: RO:0000052 UBERON:0001691 ! inheres in external ear [Term] id: OBA:0002080 name: external acoustic meatus size def: "The size of a external acoustic meatus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of external acoustic meatus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0006033 ! external auditory canal morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001352 ! inheres in external acoustic meatus relationship: RO:0000052 UBERON:0001352 ! inheres in external acoustic meatus [Term] id: OBA:0002102 name: neck length def: "The length of a neck." [AUTO:patterns/patterns/entity_attribute] synonym: "length of neck" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002103 ! neck size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0000974 ! inheres in neck [Term] id: OBA:0002103 name: neck size def: "The size of a neck." [AUTO:patterns/patterns/entity_attribute] synonym: "size of neck" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0005710 ! neck morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000974 ! inheres in neck relationship: RO:0000052 UBERON:0000974 ! inheres in neck [Term] id: OBA:0002132 name: dentition position def: "The position of a dentition." [AUTO:patterns/patterns/entity_attribute] synonym: "position of dentition" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0100003 ! anatomical entity attribute is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0003672 ! inheres in dentition relationship: RO:0000052 UBERON:0003672 ! inheres in dentition [Term] id: OBA:0002134 name: dentition size def: "The size of a dentition." [AUTO:patterns/patterns/entity_attribute] synonym: "size of dentition" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0004155 ! skeletal system morphology is_a: OBA:2045412 ! anatomical entity morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003672 ! inheres in dentition relationship: RO:0000052 UBERON:0003672 ! inheres in dentition [Term] id: OBA:0002161 name: diaphysis length def: "The length of a diaphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "length of diaphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002587 ! diaphysis size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004769 ! inheres in diaphysis [Term] id: OBA:0002162 name: ilium size def: "The size of a ilium." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ilium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: OBA:VT0005354 ! ilium morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001273 ! inheres in ilium relationship: RO:0000052 UBERON:0001273 ! inheres in ilium [Term] id: OBA:0002168 name: skin of body size def: "The size of a skin of body." [AUTO:patterns/patterns/entity_attribute] synonym: "size of skin of body" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:1000459 ! skin of body quality is_a: OBA:VT0100020 ! integumentary system morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002097 ! inheres in skin of body relationship: RO:0000052 UBERON:0002097 ! inheres in skin of body [Term] id: OBA:0002188 name: manus size def: "The size of a manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0000572 ! autopod morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002398 ! inheres in manus relationship: RO:0000052 UBERON:0002398 ! inheres in manus [Term] id: OBA:0002191 name: distal segment of manual digit position def: "The position of a distal segment of manual digit." [AUTO:patterns/patterns/entity_attribute] synonym: "position of distal segment of manual digit" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000423 ! distal segment of manual digit quality is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0009552 ! inheres in distal segment of manual digit relationship: RO:0000052 UBERON:0009552 ! inheres in distal segment of manual digit [Term] id: OBA:0002195 name: metacarpal bone size def: "The size of a metacarpal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metacarpal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002651 ! long bone size is_a: OBA:0003763 ! metacarpal bone morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002374 ! inheres in metacarpal bone relationship: RO:0000052 UBERON:0002374 ! inheres in metacarpal bone [Term] id: OBA:0002214 name: manual digit size def: "The size of a manual digit." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0002110 ! digit morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002389 ! inheres in manual digit relationship: RO:0000052 UBERON:0002389 ! inheres in manual digit [Term] id: OBA:0002225 name: diastema between upper central incisors length def: "The length of a diastema between upper central incisors." [AUTO:patterns/patterns/entity_attribute] synonym: "length of diastema between upper central incisors" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: FOVT:0001346 ! diastema between central incisors length is_a: OBA:0003499 ! midface morphology intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0035116 ! inheres in diastema between upper central incisors relationship: RO:0000052 UBERON:0035116 ! inheres in diastema between upper central incisors [Term] id: OBA:0002251 name: metatarsal bone size def: "The size of a metatarsal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metatarsal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002651 ! long bone size is_a: OBA:VT0003072 ! metatarsus morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001448 ! inheres in metatarsal bone relationship: RO:0000052 UBERON:0001448 ! inheres in metatarsal bone [Term] id: OBA:0002261 name: pedal digit length def: "The length of a pedal digit." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002262 ! pedal digit size is_a: OBA:VT0002544 ! digit length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001466 ! inheres in pedal digit [Term] id: OBA:0002262 name: pedal digit size def: "The size of a pedal digit." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:1000314 ! pedal digit quality is_a: OBA:VT0000556 ! hindlimb morphology trait is_a: OBA:VT0002110 ! digit morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001466 ! inheres in pedal digit relationship: RO:0000052 UBERON:0001466 ! inheres in pedal digit [Term] id: OBA:0002264 name: pedal digit 1 length def: "The length of a pedal digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002261 ! pedal digit length is_a: OBA:0003048 ! pedal digit 1 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003631 ! inheres in pedal digit 1 [Term] id: OBA:0002265 name: calcaneus morphology def: "The morphology of a calcaneus." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of calcaneus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0002810 ! tarsal bone morphology intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001450 ! characteristic of part of calcaneus relationship: RO:0002314 UBERON:0001450 ! characteristic of part of calcaneus [Term] id: OBA:0002267 name: distal phalanx of pes length def: "The length of a distal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003079 ! distal phalanx of pes size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003867 ! inheres in distal phalanx of pes [Term] id: OBA:0002271 name: pedal digit 2 length def: "The length of a pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002261 ! pedal digit length is_a: OBA:0003358 ! pedal digit 2 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003632 ! inheres in pedal digit 2 [Term] id: OBA:0002334 name: nipple size def: "The size of a nipple." [AUTO:patterns/patterns/entity_attribute] synonym: "size of nipple" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0006078 ! nipple morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002030 ! inheres in relationship: RO:0000052 UBERON:0002030 ! inheres in [Term] id: OBA:0002336 name: nipple position def: "The position of a nipple." [AUTO:patterns/patterns/entity_attribute] synonym: "position of nipple" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000057 ! gland quality is_a: OBA:VT0100003 ! organism subdivision trait is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0002030 ! inheres in relationship: RO:0000052 UBERON:0002030 ! inheres in [Term] id: OBA:0002346 name: foramen magnum size def: "The size of a foramen magnum." [AUTO:patterns/patterns/entity_attribute] synonym: "size of foramen magnum" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0005278 ! foramen magnum morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003687 ! inheres in foramen magnum relationship: RO:0000052 UBERON:0003687 ! inheres in foramen magnum [Term] id: OBA:0002360 name: trochanter size def: "The size of a trochanter." [AUTO:patterns/patterns/entity_attribute] synonym: "size of trochanter" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0004029 ! trochanter morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000980 ! inheres in trochanter relationship: RO:0000052 UBERON:0000980 ! inheres in trochanter [Term] id: OBA:0002374 name: radius bone size def: "The size of a radius bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of radius bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002651 ! long bone size is_a: OBA:0002657 ! forelimb zeugopod bone size is_a: OBA:VT0000552 ! radius morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001423 ! inheres in radius bone relationship: RO:0000052 UBERON:0001423 ! inheres in radius bone [Term] id: OBA:0002379 name: ulna size def: "The size of a ulna." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ulna" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002651 ! long bone size is_a: OBA:0002657 ! forelimb zeugopod bone size is_a: OBA:VT0005108 ! ulna morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001424 ! inheres in ulna relationship: RO:0000052 UBERON:0001424 ! inheres in ulna [Term] id: OBA:0002381 name: long bone length def: "The length of a long bone." [AUTO:patterns/patterns/entity_attribute] synonym: "length of long bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002651 ! long bone size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002495 ! inheres in long bone [Term] id: OBA:0002382 name: tarsal region size def: "The size of a tarsal region." [AUTO:patterns/patterns/entity_attribute] synonym: "size of tarsal region" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0005104 ! tarsus morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004454 ! inheres in tarsal region relationship: RO:0000052 UBERON:0004454 ! inheres in tarsal region [Term] id: OBA:0002383 name: skeletal joint size def: "The size of a skeletal joint." [AUTO:patterns/patterns/entity_attribute] synonym: "size of skeletal joint" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0003754 ! skeletal joint morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000982 ! inheres in skeletal joint relationship: RO:0000052 UBERON:0000982 ! inheres in skeletal joint [Term] id: OBA:0002384 name: fibula size def: "The size of a fibula." [AUTO:patterns/patterns/entity_attribute] synonym: "size of fibula" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002651 ! long bone size is_a: OBA:VT0002187 ! fibula morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001446 ! inheres in fibula relationship: RO:0000052 UBERON:0001446 ! inheres in fibula [Term] id: OBA:0002386 name: patella size def: "The size of a patella." [AUTO:patterns/patterns/entity_attribute] synonym: "size of patella" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000138 ! bone element size is_a: OBA:VT0005353 ! patella morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002446 ! inheres in patella relationship: RO:0000052 UBERON:0002446 ! inheres in patella [Term] id: OBA:0002389 name: proximal epiphysis of femur size def: "The size of a proximal epiphysis of femur." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal epiphysis of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003163 ! epiphysis size is_a: OBA:VT0000559 ! femur morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004412 ! inheres in proximal epiphysis of femur relationship: RO:0000052 UBERON:0004412 ! inheres in proximal epiphysis of femur [Term] id: OBA:0002390 name: pubis size def: "The size of a pubis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pubis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: OBA:2050103 ! hip bone size is_a: OBA:VT0010088 ! pubis morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001275 ! inheres in pubis relationship: RO:0000052 UBERON:0001275 ! inheres in pubis [Term] id: OBA:0002391 name: ischium size def: "The size of a ischium." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ischium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: OBA:2050103 ! hip bone size is_a: OBA:VT0010087 ! ischium morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001274 ! inheres in ischium relationship: RO:0000052 UBERON:0001274 ! inheres in ischium [Term] id: OBA:0002393 name: acetabular part of hip bone position def: "The position of a acetabular part of hip bone." [AUTO:patterns/patterns/entity_attribute] synonym: "position of acetabular part of hip bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000334 ! acetabular part of hip bone quality is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0001269 ! inheres in acetabular part of hip bone relationship: RO:0000052 UBERON:0001269 ! inheres in acetabular part of hip bone [Term] id: OBA:0002395 name: pubic symphysis size def: "The size of a pubic symphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pubic symphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002383 ! skeletal joint size is_a: OBA:0004782 ! pubic symphysis morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003699 ! inheres in pubic symphysis relationship: RO:0000052 UBERON:0003699 ! inheres in pubic symphysis [Term] id: OBA:0002412 name: acetabular part of hip bone size def: "The size of a acetabular part of hip bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of acetabular part of hip bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0003754 ! skeletal joint morphology is_a: OBA:1000334 ! acetabular part of hip bone quality is_a: OBA:VT0005354 ! ilium morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001269 ! inheres in acetabular part of hip bone relationship: RO:0000052 UBERON:0001269 ! inheres in acetabular part of hip bone [Term] id: OBA:0002413 name: pelvic girdle bone/zone size def: "The size of a pelvic girdle bone/zone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pelvic girdle bone/zone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003356 ! pelvic girdle bone/zone morphology is_a: OBA:1000138 ! bone element size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0007830 ! inheres in pelvic girdle bone/zone relationship: RO:0000052 UBERON:0007830 ! inheres in pelvic girdle bone/zone [Term] id: OBA:0002434 name: fused sacrum position def: "The position of a fused sacrum." [AUTO:patterns/patterns/entity_attribute] synonym: "position of fused sacrum" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100003 ! organism subdivision trait is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0003690 ! inheres in fused sacrum relationship: RO:0000052 UBERON:0003690 ! inheres in fused sacrum [Term] id: OBA:0002452 name: middle phalanx of pes length def: "The length of a middle phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003083 ! middle phalanx of pes size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003866 ! inheres in middle phalanx of pes [Term] id: OBA:0002474 name: humerus diaphysis size def: "The size of a humerus diaphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of humerus diaphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0005296 ! humerus morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004652 ! inheres in humerus diaphysis relationship: RO:0000052 UBERON:0004652 ! inheres in humerus diaphysis [Term] id: OBA:0002478 name: forelimb zeugopod bone morphology def: "The morphology of a forelimb zeugopod bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of forelimb zeugopod bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003695 ! bone of appendage girdle complex morphology is_a: OBA:1000066 ! endochondral bone morphology is_a: OBA:VT0003855 ! forelimb zeugopod morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003466 ! characteristic of part of forelimb zeugopod bone relationship: RO:0002314 UBERON:0003466 ! characteristic of part of forelimb zeugopod bone [Term] id: OBA:0002496 name: epiphysis of radius size def: "The size of a epiphysis of radius." [AUTO:patterns/patterns/entity_attribute] synonym: "size of epiphysis of radius" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003163 ! epiphysis size is_a: OBA:VT0000552 ! radius morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004385 ! inheres in epiphysis of radius relationship: RO:0000052 UBERON:0004385 ! inheres in epiphysis of radius [Term] id: OBA:0002514 name: distal phalanx of manual digit 3 length def: "The length of a distal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004312 ! inheres in distal phalanx of manual digit 3 [Term] id: OBA:0002517 name: middle phalanx of manual digit 5 length def: "The length of a middle phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002895 ! middle phalanx of manual digit 5 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004323 ! inheres in middle phalanx of manual digit 5 [Term] id: OBA:0002519 name: distal phalanx of manual digit 5 length def: "The length of a distal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002909 ! distal phalanx of manual digit 5 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004314 ! inheres in distal phalanx of manual digit 5 [Term] id: OBA:0002546 name: facial skeleton size def: "The size of a facial skeleton." [AUTO:patterns/patterns/entity_attribute] synonym: "size of facial skeleton" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "viscerocranium size" RELATED [] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0005274 ! facial skeleton morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0011156 ! inheres in facial skeleton relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0011156 ! inheres in facial skeleton [Term] id: OBA:0002556 name: fused sacrum size def: "The size of a fused sacrum." [AUTO:patterns/patterns/entity_attribute] synonym: "size of fused sacrum" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0004993 ! fused sacrum morphology is_a: OBA:1000138 ! bone element size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003690 ! inheres in fused sacrum relationship: RO:0000052 UBERON:0003690 ! inheres in fused sacrum [Term] id: OBA:0002564 name: tarsal bone size def: "The size of a tarsal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of tarsal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002810 ! tarsal bone morphology is_a: OBA:1000138 ! bone element size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001447 ! inheres in tarsal bone relationship: RO:0000052 UBERON:0001447 ! inheres in tarsal bone [Term] id: OBA:0002565 name: metatarsal bone of digit 3 length def: "The length of a metatarsal bone of digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 3 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 3 maximal length (M1)" EXACT [] synonym: "metatarsal III greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "third metatarsal maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000413 ! metatarsal bone of digit 3 quality intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003652 ! inheres in metatarsal bone of digit 3 [Term] id: OBA:0002567 name: metatarsal bone of digit 4 length def: "The length of a metatarsal bone of digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 4 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 4 maximal length (M1)" EXACT [] synonym: "metatarsal IV greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metatarsal IV maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000611 ! metatarsal bone of digit 4 quality intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003653 ! inheres in metatarsal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003653 ! inheres in metatarsal bone of digit 4 [Term] id: OBA:0002569 name: metatarsal bone of digit 5 length def: "The length of a metatarsal bone of digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 5 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 5 maximal length (M1)" EXACT [] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000254 ! metatarsal bone of digit 5 quality intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003654 ! inheres in metatarsal bone of digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003654 ! inheres in metatarsal bone of digit 5 [Term] id: OBA:0002587 name: diaphysis size def: "The size of a diaphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of diaphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0004214 ! long bone diaphysis morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004769 ! inheres in diaphysis relationship: RO:0000052 UBERON:0004769 ! inheres in diaphysis [Term] id: OBA:0002588 name: phalanx of pes length def: "The length of a phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:VT0002543 ! phalanx length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001449 ! inheres in phalanx of pes [Term] id: OBA:0002603 name: synovial joint size def: "The size of a synovial joint." [AUTO:patterns/patterns/entity_attribute] synonym: "size of synovial joint" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002383 ! skeletal joint size is_a: OBA:1000205 ! synovial joint quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002217 ! inheres in synovial joint relationship: RO:0000052 UBERON:0002217 ! inheres in synovial joint [Term] id: OBA:0002620 name: chest size def: "The size of a chest." [AUTO:patterns/patterns/entity_attribute] synonym: "size of chest" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0003917 ! chest morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001443 ! inheres in relationship: RO:0000052 UBERON:0001443 ! inheres in [Term] id: OBA:0002651 name: long bone size def: "The size of a long bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of long bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000138 ! bone element size is_a: OBA:VT0003723 ! long bone morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002495 ! inheres in long bone relationship: RO:0000052 UBERON:0002495 ! inheres in long bone [Term] id: OBA:0002653 name: pedal digit 3 length def: "The length of a pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002261 ! pedal digit length is_a: OBA:0003359 ! pedal digit 3 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003633 ! inheres in pedal digit 3 [Term] id: OBA:0002657 name: forelimb zeugopod bone size def: "The size of a forelimb zeugopod bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of forelimb zeugopod bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002478 ! forelimb zeugopod bone morphology is_a: OBA:1000138 ! bone element size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003466 ! inheres in forelimb zeugopod bone relationship: RO:0000052 UBERON:0003466 ! inheres in forelimb zeugopod bone [Term] id: OBA:0002661 name: middle phalanx of manus length def: "The length of a middle phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002683 ! phalanx of manus length is_a: OBA:0003009 ! middle phalanx of manus size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003864 ! inheres in middle phalanx of manus [Term] id: OBA:0002674 name: phalanx size def: "The size of a phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002651 ! long bone size is_a: OBA:VT0005306 ! phalanx morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003221 ! inheres in phalanx relationship: RO:0000052 UBERON:0003221 ! inheres in phalanx [Term] id: OBA:0002676 name: metacarpal bone of digit 2 length def: "The length of a metacarpal bone of digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 2 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 2 maximal length (M1)" EXACT [] synonym: "metacarpal II greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metacarpal II length" EXACT [] synonym: "metacarpal II maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003646 ! inheres in metacarpal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003646 ! inheres in metacarpal bone of digit 2 [Term] id: OBA:0002681 name: proximal phalanx of manus length def: "The length of a proximal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002683 ! phalanx of manus length is_a: OBA:0003012 ! proximal phalanx of manus size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002234 ! inheres in proximal phalanx of manus [Term] id: OBA:0002683 name: phalanx of manus length def: "The length of a phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:VT0002543 ! phalanx length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001436 ! inheres in phalanx of manus [Term] id: OBA:0002703 name: primary dentition size def: "The size of a primary dentition." [AUTO:patterns/patterns/entity_attribute] synonym: "size of primary dentition" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002134 ! dentition size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0007116 ! inheres in primary dentition relationship: RO:0000052 UBERON:0007116 ! inheres in primary dentition [Term] id: OBA:0002710 name: premolar tooth size def: "The size of a premolar tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "size of premolar tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003215 ! premolar tooth morphology is_a: OBA:1000112 ! tooth size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0007120 ! inheres in premolar tooth relationship: RO:0000052 UBERON:0007120 ! inheres in premolar tooth [Term] id: OBA:0002716 name: distal epiphysis of radius size def: "The size of a distal epiphysis of radius." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal epiphysis of radius" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002496 ! epiphysis of radius size is_a: OBA:1000600 ! distal epiphysis of radius quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004407 ! inheres in distal epiphysis of radius relationship: RO:0000052 UBERON:0004407 ! inheres in distal epiphysis of radius [Term] id: OBA:0002726 name: distal epiphysis of femur size def: "The size of a distal epiphysis of femur." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal epiphysis of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003163 ! epiphysis size is_a: OBA:1000180 ! distal epiphysis of femur quality is_a: OBA:VT0000559 ! femur morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004406 ! inheres in distal epiphysis of femur relationship: RO:0000052 UBERON:0004406 ! inheres in distal epiphysis of femur [Term] id: OBA:0002741 name: glenoid fossa size def: "The size of a glenoid fossa." [AUTO:patterns/patterns/entity_attribute] synonym: "size of glenoid fossa" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000409 ! glenoid fossa quality is_a: OBA:2045412 ! anatomical entity morphology is_a: OBA:VT0010003 ! bone morphology trait is_a: OBA:VT0010089 ! shoulder girdle morphology trait is_a: OBA:VT0010091 ! appendicular skeleton morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0006657 ! inheres in glenoid fossa relationship: RO:0000052 UBERON:0006657 ! inheres in glenoid fossa [Term] id: OBA:0002807 name: pedal digit 4 length def: "The length of a pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002261 ! pedal digit length is_a: OBA:0003360 ! pedal digit 4 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003634 ! inheres in pedal digit 4 [Term] id: OBA:0002810 name: tarsal bone morphology def: "The morphology of a tarsal bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of tarsal bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003695 ! bone of appendage girdle complex morphology is_a: OBA:1000066 ! endochondral bone morphology is_a: OBA:1000508 ! tarsal bone quality is_a: OBA:VT0005104 ! tarsus morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001447 ! characteristic of part of tarsal bone [Term] id: OBA:0002823 name: vertebra size def: "The size of a vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "size of vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000138 ! bone element size is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002412 ! inheres in vertebra relationship: RO:0000052 UBERON:0002412 ! inheres in vertebra [Term] id: OBA:0002828 name: lumbar vertebra 5 size def: "The size of a lumbar vertebra 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of lumbar vertebra 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010518 ! lumbar vertebra size trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004621 ! inheres in lumbar vertebra 5 relationship: RO:0000052 UBERON:0004621 ! inheres in lumbar vertebra 5 [Term] id: OBA:0002830 name: cervical vertebra size def: "The size of a cervical vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "size of cervical vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002823 ! vertebra size is_a: OBA:0003760 ! cervical vertebra morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002413 ! inheres in cervical vertebra relationship: RO:0000052 UBERON:0002413 ! inheres in cervical vertebra [Term] id: OBA:0002845 name: external ear morphology def: "The morphology of a external ear." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of external ear" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0002102 ! ear morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001691 ! characteristic of part of external ear relationship: RO:0002314 UBERON:0001691 ! characteristic of part of external ear [Term] id: OBA:0002854 name: vagina size def: "The size of a vagina." [AUTO:patterns/patterns/entity_attribute] synonym: "size of vagina" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0001139 ! vagina morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000996 ! inheres in vagina relationship: RO:0000052 UBERON:0000996 ! inheres in vagina [Term] id: OBA:0002863 name: lesser trochanter size def: "The size of a lesser trochanter." [AUTO:patterns/patterns/entity_attribute] synonym: "size of lesser trochanter" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002360 ! trochanter size is_a: OBA:VT0000131 ! long bone epiphysis morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002504 ! inheres in lesser trochanter relationship: RO:0000052 UBERON:0002504 ! inheres in lesser trochanter [Term] id: OBA:0002864 name: head of femur size def: "The size of a head of femur." [AUTO:patterns/patterns/entity_attribute] synonym: "size of head of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000131 ! long bone epiphysis morphology trait is_a: OBA:VT0000559 ! femur morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0006767 ! inheres in head of femur relationship: RO:0000052 UBERON:0006767 ! inheres in head of femur [Term] id: OBA:0002895 name: middle phalanx of manual digit 5 size def: "The size of a middle phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002931 ! manual digit 5 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004323 ! inheres in middle phalanx of manual digit 5 relationship: RO:0000052 UBERON:0004323 ! inheres in middle phalanx of manual digit 5 [Term] id: OBA:0002903 name: proximal phalanx of manual digit 5 length def: "The length of a proximal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002904 ! proximal phalanx of manual digit 5 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004331 ! inheres in proximal phalanx of manual digit 5 [Term] id: OBA:0002904 name: proximal phalanx of manual digit 5 size def: "The size of a proximal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002931 ! manual digit 5 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004331 ! inheres in proximal phalanx of manual digit 5 relationship: RO:0000052 UBERON:0004331 ! inheres in proximal phalanx of manual digit 5 [Term] id: OBA:0002909 name: distal phalanx of manual digit 5 size def: "The size of a distal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002931 ! manual digit 5 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004314 ! inheres in distal phalanx of manual digit 5 relationship: RO:0000052 UBERON:0004314 ! inheres in distal phalanx of manual digit 5 [Term] id: OBA:0002918 name: distal phalanx of manual digit 4 length def: "The length of a distal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002919 ! distal phalanx of manual digit 4 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004313 ! inheres in distal phalanx of manual digit 4 [Term] id: OBA:0002919 name: distal phalanx of manual digit 4 size def: "The size of a distal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002936 ! manual digit 4 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004313 ! inheres in distal phalanx of manual digit 4 relationship: RO:0000052 UBERON:0004313 ! inheres in distal phalanx of manual digit 4 [Term] id: OBA:0002920 name: middle phalanx of manual digit 4 size def: "The size of a middle phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002936 ! manual digit 4 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004322 ! inheres in middle phalanx of manual digit 4 relationship: RO:0000052 UBERON:0004322 ! inheres in middle phalanx of manual digit 4 [Term] id: OBA:0002921 name: middle phalanx of manual digit 4 length def: "The length of a middle phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002920 ! middle phalanx of manual digit 4 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004322 ! inheres in middle phalanx of manual digit 4 [Term] id: OBA:0002923 name: proximal phalanx of manual digit 4 length def: "The length of a proximal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002927 ! proximal phalanx of manual digit 4 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004330 ! inheres in proximal phalanx of manual digit 4 [Term] id: OBA:0002927 name: proximal phalanx of manual digit 4 size def: "The size of a proximal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002936 ! manual digit 4 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004330 ! inheres in proximal phalanx of manual digit 4 relationship: RO:0000052 UBERON:0004330 ! inheres in proximal phalanx of manual digit 4 [Term] id: OBA:0002931 name: manual digit 5 phalanx size def: "The size of a manual digit 5 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 5 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003639 ! inheres in manual digit 5 phalanx relationship: RO:0000052 UBERON:0003639 ! inheres in manual digit 5 phalanx [Term] id: OBA:0002935 name: manual digit length def: "The length of a manual digit." [AUTO:patterns/patterns/entity_attribute] synonym: "length of manual digit" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002214 ! manual digit size is_a: OBA:VT0002544 ! digit length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002389 ! inheres in manual digit [Term] id: OBA:0002936 name: manual digit 4 phalanx size def: "The size of a manual digit 4 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 4 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000158 ! manual digit 4 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003638 ! inheres in manual digit 4 phalanx relationship: RO:0000052 UBERON:0003638 ! inheres in manual digit 4 phalanx [Term] id: OBA:0002939 name: distal phalanx of manual digit 3 size def: "The size of a distal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002948 ! manual digit 3 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004312 ! inheres in distal phalanx of manual digit 3 relationship: RO:0000052 UBERON:0004312 ! inheres in distal phalanx of manual digit 3 [Term] id: OBA:0002943 name: middle phalanx of manual digit 3 size def: "The size of a middle phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002948 ! manual digit 3 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004321 ! inheres in middle phalanx of manual digit 3 relationship: RO:0000052 UBERON:0004321 ! inheres in middle phalanx of manual digit 3 [Term] id: OBA:0002947 name: middle phalanx of manual digit 3 length def: "The length of a middle phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002943 ! middle phalanx of manual digit 3 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004321 ! inheres in middle phalanx of manual digit 3 [Term] id: OBA:0002948 name: manual digit 3 phalanx size def: "The size of a manual digit 3 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 3 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003637 ! inheres in manual digit 3 phalanx relationship: RO:0000052 UBERON:0003637 ! inheres in manual digit 3 phalanx [Term] id: OBA:0002952 name: proximal phalanx of manual digit 3 size def: "The size of a proximal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002948 ! manual digit 3 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004329 ! inheres in proximal phalanx of manual digit 3 relationship: RO:0000052 UBERON:0004329 ! inheres in proximal phalanx of manual digit 3 [Term] id: OBA:0002956 name: proximal phalanx of manual digit 3 length def: "The length of a proximal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004329 ! inheres in proximal phalanx of manual digit 3 [Term] id: OBA:0002962 name: manual digit 2 phalanx size def: "The size of a manual digit 2 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 2 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003636 ! inheres in manual digit 2 phalanx relationship: RO:0000052 UBERON:0003636 ! inheres in manual digit 2 phalanx [Term] id: OBA:0002966 name: distal phalanx of manual digit 2 size def: "The size of a distal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002962 ! manual digit 2 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004311 ! inheres in distal phalanx of manual digit 2 relationship: RO:0000052 UBERON:0004311 ! inheres in distal phalanx of manual digit 2 [Term] id: OBA:0002970 name: distal phalanx of manual digit 2 length def: "The length of a distal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002966 ! distal phalanx of manual digit 2 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004311 ! inheres in distal phalanx of manual digit 2 [Term] id: OBA:0002971 name: middle phalanx of manual digit 2 size def: "The size of a middle phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002962 ! manual digit 2 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004320 ! inheres in middle phalanx of manual digit 2 relationship: RO:0000052 UBERON:0004320 ! inheres in middle phalanx of manual digit 2 [Term] id: OBA:0002975 name: middle phalanx of manual digit 2 length def: "The length of a middle phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002971 ! middle phalanx of manual digit 2 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004320 ! inheres in middle phalanx of manual digit 2 [Term] id: OBA:0002976 name: proximal phalanx of manual digit 2 size def: "The size of a proximal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002962 ! manual digit 2 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004328 ! inheres in proximal phalanx of manual digit 2 relationship: RO:0000052 UBERON:0004328 ! inheres in proximal phalanx of manual digit 2 [Term] id: OBA:0002980 name: proximal phalanx of manual digit 2 length def: "The length of a proximal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002976 ! proximal phalanx of manual digit 2 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004328 ! inheres in proximal phalanx of manual digit 2 [Term] id: OBA:0002986 name: proximal phalanx of manual digit 1 size def: "The size of a proximal phalanx of manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:0005188 ! manual digit 1 morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004338 ! inheres in proximal phalanx of manual digit 1 relationship: RO:0000052 UBERON:0004338 ! inheres in proximal phalanx of manual digit 1 [Term] id: OBA:0002989 name: proximal phalanx of manual digit 1 length def: "The length of a proximal phalanx of manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002986 ! proximal phalanx of manual digit 1 size is_a: OBA:0002995 ! manual digit 1 phalanx length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004338 ! inheres in proximal phalanx of manual digit 1 [Term] id: OBA:0002990 name: distal phalanx of manual digit 1 size def: "The size of a distal phalanx of manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:0005188 ! manual digit 1 morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004337 ! inheres in distal phalanx of manual digit 1 relationship: RO:0000052 UBERON:0004337 ! inheres in distal phalanx of manual digit 1 [Term] id: OBA:0002995 name: manual digit 1 phalanx length def: "The length of a manual digit 1 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "length of manual digit 1 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002683 ! phalanx of manus length is_a: OBA:0005188 ! manual digit 1 morphology intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003620 ! inheres in manual digit 1 phalanx relationship: RO:0000052 UBERON:0003620 ! inheres in manual digit 1 phalanx [Term] id: OBA:0002999 name: phalanx of manus size def: "The size of a phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002674 ! phalanx size is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0010104 ! forelimb long bone morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001436 ! inheres in phalanx of manus relationship: RO:0000052 UBERON:0001436 ! inheres in phalanx of manus [Term] id: OBA:0003003 name: manual digit 1 length def: "The length of a manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002935 ! manual digit length is_a: OBA:0003234 ! manual digit 1 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001463 ! inheres in manual digit 1 [Term] id: OBA:0003005 name: forelimb zeugopod bone length def: "The length of a forelimb zeugopod bone." [AUTO:patterns/patterns/entity_attribute] synonym: "length of forelimb zeugopod bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002657 ! forelimb zeugopod bone size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003466 ! inheres in forelimb zeugopod bone [Term] id: OBA:0003006 name: distal phalanx of manus size def: "The size of a distal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003865 ! inheres in distal phalanx of manus relationship: RO:0000052 UBERON:0003865 ! inheres in distal phalanx of manus [Term] id: OBA:0003009 name: middle phalanx of manus size def: "The size of a middle phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000382 ! middle phalanx of manus quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003864 ! inheres in middle phalanx of manus relationship: RO:0000052 UBERON:0003864 ! inheres in middle phalanx of manus [Term] id: OBA:0003012 name: proximal phalanx of manus size def: "The size of a proximal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002234 ! inheres in proximal phalanx of manus relationship: RO:0000052 UBERON:0002234 ! inheres in proximal phalanx of manus [Term] id: OBA:0003016 name: distal phalanx of manus length def: "The length of a distal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002683 ! phalanx of manus length is_a: OBA:0003006 ! distal phalanx of manus size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003865 ! inheres in distal phalanx of manus [Term] id: OBA:0003040 name: metacarpal bone of digit 1 size def: "The size of a metacarpal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metacarpal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002195 ! metacarpal bone size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003645 ! inheres in metacarpal bone of digit 1 relationship: RO:0000052 UBERON:0003645 ! inheres in metacarpal bone of digit 1 [Term] id: OBA:0003043 name: metacarpal bone of digit 1 length def: "The length of a metacarpal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 1 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 1 maximal length (M1)" EXACT [] synonym: "metacarpal I length" EXACT [] is_a: OBA:0003040 ! metacarpal bone of digit 1 size is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003645 ! inheres in metacarpal bone of digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003044 name: metacarpal bone of digit 3 length def: "The length of a metacarpal bone of digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpa III greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metacarpal bone of digit 3 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 3 maximal length (M1)" EXACT [] synonym: "metacarpal III length" EXACT [] synonym: "third metacarpal maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003647 ! inheres in metacarpal bone of digit 3 [Term] id: OBA:0003045 name: metacarpal bone of digit 4 length def: "The length of a metacarpal bone of digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 4 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 4 maximal length (M1)" EXACT [] synonym: "metacarpal IV greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metacarpal IV length" EXACT [] synonym: "metacarpal IV maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003648 ! inheres in metacarpal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003648 ! inheres in metacarpal bone of digit 4 [Term] id: OBA:0003046 name: metacarpal bone of digit 5 length def: "The length of a metacarpal bone of digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 5 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 5 maximal length (M1)" EXACT [] synonym: "metacarpal V greatest length" RELATED [ISBN:9780873659505] synonym: "metacarpal V length" EXACT [] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003649 ! inheres in metacarpal bone of digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003649 ! inheres in metacarpal bone of digit 5 [Term] id: OBA:0003047 name: metacarpal bone length def: "The length of a metacarpal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: FOVT:0001141 ! metapodial bone length is_a: OBA:0002195 ! metacarpal bone size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002374 ! inheres in metacarpal bone [Term] id: OBA:0003048 name: pedal digit 1 size def: "The size of a pedal digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002262 ! pedal digit size is_a: OBA:0004592 ! pedal digit 1 morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003631 ! inheres in pedal digit 1 relationship: RO:0000052 UBERON:0003631 ! inheres in pedal digit 1 [Term] id: OBA:0003049 name: pedal digit 1 phalanx size def: "The size of a pedal digit 1 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 1 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:0004592 ! pedal digit 1 morphology is_a: OBA:1000161 ! pedal digit 1 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003640 ! inheres in pedal digit 1 phalanx relationship: RO:0000052 UBERON:0003640 ! inheres in pedal digit 1 phalanx [Term] id: OBA:0003053 name: metatarsal bone of digit 1 size def: "The size of a metatarsal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metatarsal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000597 ! metatarsal bone of digit 1 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003650 ! inheres in metatarsal bone of digit 1 relationship: RO:0000052 UBERON:0003650 ! inheres in metatarsal bone of digit 1 [Term] id: OBA:0003057 name: distal phalanx of pedal digit 1 size def: "The size of a distal phalanx of pedal digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003049 ! pedal digit 1 phalanx size is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004315 ! inheres in distal phalanx of pedal digit 1 relationship: RO:0000052 UBERON:0004315 ! inheres in distal phalanx of pedal digit 1 [Term] id: OBA:0003061 name: proximal phalanx of pedal digit 1 size def: "The size of a proximal phalanx of pedal digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003049 ! pedal digit 1 phalanx size is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004332 ! inheres in proximal phalanx of pedal digit 1 relationship: RO:0000052 UBERON:0004332 ! inheres in proximal phalanx of pedal digit 1 [Term] id: OBA:0003066 name: metatarsal bone of digit 1 length def: "The length of a metatarsal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 1 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 1 maximal length (M1)" EXACT [] is_a: OBA:0003053 ! metatarsal bone of digit 1 size is_a: OBA:0004033 ! metatarsal bone length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003650 ! inheres in metatarsal bone of digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003067 name: pedal digit 1 phalanx length def: "The length of a pedal digit 1 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit 1 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003049 ! pedal digit 1 phalanx size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003640 ! inheres in pedal digit 1 phalanx [Term] id: OBA:0003075 name: phalanx of pes size def: "The size of a phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002674 ! phalanx size is_a: OBA:1000501 ! phalanx of pes quality is_a: OBA:VT0010105 ! hindlimb long bone morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001449 ! inheres in phalanx of pes relationship: RO:0000052 UBERON:0001449 ! inheres in phalanx of pes [Term] id: OBA:0003079 name: distal phalanx of pes size def: "The size of a distal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003867 ! inheres in distal phalanx of pes relationship: RO:0000052 UBERON:0003867 ! inheres in distal phalanx of pes [Term] id: OBA:0003083 name: middle phalanx of pes size def: "The size of a middle phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003866 ! inheres in middle phalanx of pes relationship: RO:0000052 UBERON:0003866 ! inheres in middle phalanx of pes [Term] id: OBA:0003087 name: proximal phalanx of pes size def: "The size of a proximal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000212 ! proximal phalanx of pes quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003868 ! inheres in proximal phalanx of pes relationship: RO:0000052 UBERON:0003868 ! inheres in proximal phalanx of pes [Term] id: OBA:0003100 name: hard palate size def: "The size of a hard palate." [AUTO:patterns/patterns/entity_attribute] synonym: "size of hard palate" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0003756 ! hard palate morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003216 ! inheres in hard palate relationship: RO:0000052 UBERON:0003216 ! inheres in hard palate [Term] id: OBA:0003105 name: chest length def: "The length of a chest." [AUTO:patterns/patterns/entity_attribute] synonym: "length of chest" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002620 ! chest size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001443 ! inheres in [Term] id: OBA:0003111 name: pedal digit 2 phalanx size def: "The size of a pedal digit 2 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 2 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000353 ! pedal digit 2 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003641 ! inheres in pedal digit 2 phalanx relationship: RO:0000052 UBERON:0003641 ! inheres in pedal digit 2 phalanx [Term] id: OBA:0003115 name: pedal digit 3 phalanx size def: "The size of a pedal digit 3 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 3 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000378 ! pedal digit 3 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003642 ! inheres in pedal digit 3 phalanx relationship: RO:0000052 UBERON:0003642 ! inheres in pedal digit 3 phalanx [Term] id: OBA:0003119 name: pedal digit 4 phalanx size def: "The size of a pedal digit 4 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 4 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000575 ! pedal digit 4 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003862 ! inheres in pedal digit 4 phalanx relationship: RO:0000052 UBERON:0003862 ! inheres in pedal digit 4 phalanx [Term] id: OBA:0003123 name: pedal digit 5 phalanx size def: "The size of a pedal digit 5 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 5 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000329 ! pedal digit 5 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003863 ! inheres in pedal digit 5 phalanx relationship: RO:0000052 UBERON:0003863 ! inheres in pedal digit 5 phalanx [Term] id: OBA:0003127 name: proximal phalanx of pedal digit 2 size def: "The size of a proximal phalanx of pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003111 ! pedal digit 2 phalanx size is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004333 ! inheres in proximal phalanx of pedal digit 2 relationship: RO:0000052 UBERON:0004333 ! inheres in proximal phalanx of pedal digit 2 [Term] id: OBA:0003131 name: middle phalanx of pedal digit 2 size def: "The size of a middle phalanx of pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003111 ! pedal digit 2 phalanx size is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004324 ! inheres in middle phalanx of pedal digit 2 relationship: RO:0000052 UBERON:0004324 ! inheres in middle phalanx of pedal digit 2 [Term] id: OBA:0003135 name: distal phalanx of pedal digit 2 size def: "The size of a distal phalanx of pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003111 ! pedal digit 2 phalanx size is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004316 ! inheres in distal phalanx of pedal digit 2 relationship: RO:0000052 UBERON:0004316 ! inheres in distal phalanx of pedal digit 2 [Term] id: OBA:0003163 name: epiphysis size def: "The size of a epiphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of epiphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000131 ! long bone epiphysis morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001437 ! inheres in epiphysis relationship: RO:0000052 UBERON:0001437 ! inheres in epiphysis [Term] id: OBA:0003215 name: premolar tooth morphology def: "The morphology of a premolar tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of premolar tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000593 ! premolar tooth quality is_a: OBA:VT0002100 ! tooth morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0007120 ! characteristic of part of premolar tooth [Term] id: OBA:0003231 name: tragus position def: "The position of a tragus." [AUTO:patterns/patterns/entity_attribute] synonym: "position of tragus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005382 ! head trait is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0010887 ! inheres in tragus relationship: RO:0000052 UBERON:0010887 ! inheres in tragus [Term] id: OBA:0003232 name: tragus size def: "The size of a tragus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of tragus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0002177 ! outer ear morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0010887 ! inheres in tragus relationship: RO:0000052 UBERON:0010887 ! inheres in tragus [Term] id: OBA:0003233 name: distal segment of manual digit size def: "The size of a distal segment of manual digit." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal segment of manual digit" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:1000423 ! distal segment of manual digit quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0002110 ! digit morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0009552 ! inheres in distal segment of manual digit relationship: RO:0000052 UBERON:0009552 ! inheres in distal segment of manual digit [Term] id: OBA:0003234 name: manual digit 1 size def: "The size of a manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002214 ! manual digit size is_a: OBA:0005188 ! manual digit 1 morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001463 ! inheres in manual digit 1 relationship: RO:0000052 UBERON:0001463 ! inheres in manual digit 1 [Term] id: OBA:0003272 name: metatarsal bone of digit 2 length def: "The length of a metatarsal bone of digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 2 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 2 maximal length (M1)" EXACT [] synonym: "metatarsal II greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metatarsal II maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000491 ! metatarsal bone of digit 2 quality intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003651 ! inheres in metatarsal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: RO:0000052 UBERON:0003651 ! inheres in metatarsal bone of digit 2 [Term] id: OBA:0003278 name: pedal digit 5 length def: "The length of a pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002261 ! pedal digit length is_a: OBA:0003361 ! pedal digit 5 size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003635 ! inheres in pedal digit 5 [Term] id: OBA:0003281 name: proximal phalanx of pes length def: "The length of a proximal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003087 ! proximal phalanx of pes size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003868 ! inheres in proximal phalanx of pes [Term] id: OBA:0003298 name: proximal epiphysis of tibia size def: "The size of a proximal epiphysis of tibia." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal epiphysis of tibia" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003163 ! epiphysis size is_a: OBA:1000148 ! proximal epiphysis of tibia quality is_a: OBA:VT0000558 ! tibia morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0008772 ! inheres in proximal epiphysis of tibia relationship: RO:0000052 UBERON:0008772 ! inheres in proximal epiphysis of tibia [Term] id: OBA:0003304 name: midface position def: "The position of a midface." [AUTO:patterns/patterns/entity_attribute] synonym: "position of midface" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000496 ! midface quality is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0004089 ! inheres in midface relationship: RO:0000052 UBERON:0004089 ! inheres in midface [Term] id: OBA:0003306 name: calcaneus position def: "The position of a calcaneus." [AUTO:patterns/patterns/entity_attribute] synonym: "position of calcaneus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000508 ! tarsal bone quality is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0001450 ! inheres in calcaneus relationship: RO:0000052 UBERON:0001450 ! inheres in calcaneus [Term] id: OBA:0003330 name: calcaneus size def: "The size of a calcaneus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of calcaneus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002265 ! calcaneus morphology is_a: OBA:0002564 ! tarsal bone size intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001450 ! inheres in calcaneus relationship: RO:0000052 UBERON:0001450 ! inheres in calcaneus [Term] id: OBA:0003356 name: pelvic girdle bone/zone morphology def: "The morphology of a pelvic girdle bone/zone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of pelvic girdle bone/zone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003695 ! bone of appendage girdle complex morphology is_a: OBA:VT0010090 ! pelvic girdle morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0007830 ! characteristic of part of pelvic girdle bone/zone relationship: RO:0002314 UBERON:0007830 ! characteristic of part of pelvic girdle bone/zone [Term] id: OBA:0003358 name: pedal digit 2 size def: "The size of a pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002262 ! pedal digit size is_a: OBA:1000191 ! pedal digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003632 ! inheres in pedal digit 2 relationship: RO:0000052 UBERON:0003632 ! inheres in pedal digit 2 [Term] id: OBA:0003359 name: pedal digit 3 size def: "The size of a pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002262 ! pedal digit size is_a: OBA:1000446 ! pedal digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003633 ! inheres in pedal digit 3 relationship: RO:0000052 UBERON:0003633 ! inheres in pedal digit 3 [Term] id: OBA:0003360 name: pedal digit 4 size def: "The size of a pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002262 ! pedal digit size is_a: OBA:1000269 ! pedal digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003634 ! inheres in pedal digit 4 relationship: RO:0000052 UBERON:0003634 ! inheres in pedal digit 4 [Term] id: OBA:0003361 name: pedal digit 5 size def: "The size of a pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002262 ! pedal digit size is_a: OBA:1000297 ! pedal digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003635 ! inheres in pedal digit 5 relationship: RO:0000052 UBERON:0003635 ! inheres in pedal digit 5 [Term] id: OBA:0003366 name: distal phalanx of pedal digit 3 size def: "The size of a distal phalanx of pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003115 ! pedal digit 3 phalanx size is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004317 ! inheres in distal phalanx of pedal digit 3 relationship: RO:0000052 UBERON:0004317 ! inheres in distal phalanx of pedal digit 3 [Term] id: OBA:0003367 name: distal phalanx of pedal digit 4 size def: "The size of a distal phalanx of pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003119 ! pedal digit 4 phalanx size is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004318 ! inheres in distal phalanx of pedal digit 4 relationship: RO:0000052 UBERON:0004318 ! inheres in distal phalanx of pedal digit 4 [Term] id: OBA:0003368 name: distal phalanx of pedal digit 5 size def: "The size of a distal phalanx of pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003123 ! pedal digit 5 phalanx size is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004319 ! inheres in distal phalanx of pedal digit 5 relationship: RO:0000052 UBERON:0004319 ! inheres in distal phalanx of pedal digit 5 [Term] id: OBA:0003369 name: middle phalanx of pedal digit 3 size def: "The size of a middle phalanx of pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003115 ! pedal digit 3 phalanx size is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004325 ! inheres in middle phalanx of pedal digit 3 relationship: RO:0000052 UBERON:0004325 ! inheres in middle phalanx of pedal digit 3 [Term] id: OBA:0003370 name: middle phalanx of pedal digit 4 size def: "The size of a middle phalanx of pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003119 ! pedal digit 4 phalanx size is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004326 ! inheres in middle phalanx of pedal digit 4 relationship: RO:0000052 UBERON:0004326 ! inheres in middle phalanx of pedal digit 4 [Term] id: OBA:0003371 name: middle phalanx of pedal digit 5 size def: "The size of a middle phalanx of pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003123 ! pedal digit 5 phalanx size is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004327 ! inheres in middle phalanx of pedal digit 5 relationship: RO:0000052 UBERON:0004327 ! inheres in middle phalanx of pedal digit 5 [Term] id: OBA:0003372 name: proximal phalanx of pedal digit 3 size def: "The size of a proximal phalanx of pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003115 ! pedal digit 3 phalanx size is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004334 ! inheres in proximal phalanx of pedal digit 3 relationship: RO:0000052 UBERON:0004334 ! inheres in proximal phalanx of pedal digit 3 [Term] id: OBA:0003373 name: proximal phalanx of pedal digit 4 size def: "The size of a proximal phalanx of pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003119 ! pedal digit 4 phalanx size is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004335 ! inheres in proximal phalanx of pedal digit 4 relationship: RO:0000052 UBERON:0004335 ! inheres in proximal phalanx of pedal digit 4 [Term] id: OBA:0003374 name: proximal phalanx of pedal digit 5 size def: "The size of a proximal phalanx of pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003123 ! pedal digit 5 phalanx size is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004336 ! inheres in proximal phalanx of pedal digit 5 relationship: RO:0000052 UBERON:0004336 ! inheres in proximal phalanx of pedal digit 5 [Term] id: OBA:0003394 name: vagina position def: "The position of a vagina." [AUTO:patterns/patterns/entity_attribute] synonym: "position of vagina" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000213 ! female reproductive system quality is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0000996 ! inheres in vagina relationship: RO:0000052 UBERON:0000996 ! inheres in vagina [Term] id: OBA:0003407 name: ilium height def: "The height of a ilium." [AUTO:patterns/patterns/entity_attribute] synonym: "height of ilium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002162 ! ilium size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0001273 ! inheres in ilium [Term] id: OBA:0003426 name: external ear length def: "The length of a external ear." [AUTO:patterns/patterns/entity_attribute] synonym: "ear length" BROAD [] synonym: "length of external ear" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000017 ! outer ear size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001691 ! inheres in external ear relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003439 name: ear size def: "The size of a ear." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ear" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0002102 ! ear morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001690 ! inheres in ear relationship: RO:0000052 UBERON:0001690 ! inheres in ear [Term] id: OBA:0003443 name: axial skeleton plus cranial skeleton size def: "The size of a axial skeleton plus cranial skeleton." [AUTO:patterns/patterns/entity_attribute] synonym: "size of axial skeleton plus cranial skeleton" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0003694 ! axial skeleton plus cranial skeleton morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0005944 ! inheres in axial skeleton plus cranial skeleton relationship: RO:0000052 UBERON:0005944 ! inheres in axial skeleton plus cranial skeleton [Term] id: OBA:0003499 name: midface morphology def: "The morphology of a midface." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of midface" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000496 ! midface quality is_a: OBA:VT0003743 ! facial morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0004089 ! characteristic of part of midface [Term] id: OBA:0003500 name: midface length def: "The length of a midface." [AUTO:patterns/patterns/entity_attribute] synonym: "length of midface" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0003499 ! midface morphology is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0004089 ! inheres in midface relationship: RO:0000052 UBERON:0004089 ! inheres in midface [Term] id: OBA:0003618 name: zone of skin size def: "The size of a zone of skin." [AUTO:patterns/patterns/entity_attribute] synonym: "size of zone of skin" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0002096 ! skin morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0000014 ! inheres in zone of skin relationship: RO:0000052 UBERON:0000014 ! inheres in zone of skin [Term] id: OBA:0003694 name: axial skeleton plus cranial skeleton morphology def: "The morphology of a axial skeleton plus cranial skeleton." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of axial skeleton plus cranial skeleton" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0004155 ! skeletal system morphology intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0005944 ! characteristic of part of axial skeleton plus cranial skeleton relationship: RO:0002314 UBERON:0005944 ! characteristic of part of axial skeleton plus cranial skeleton [Term] id: OBA:0003695 name: bone of appendage girdle complex morphology def: "The morphology of a bone of appendage girdle complex." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of bone of appendage girdle complex" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0010003 ! bone morphology trait is_a: OBA:VT0010091 ! appendicular skeleton morphology trait is_a: OBA:VT0100003 ! organism subdivision trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0010740 ! characteristic of part of bone of appendage girdle complex relationship: RO:0002314 UBERON:0010740 ! characteristic of part of bone of appendage girdle complex [Term] id: OBA:0003722 name: jaw skeleton size def: "The size of a jaw skeleton." [AUTO:patterns/patterns/entity_attribute] synonym: "size of jaw skeleton" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0000454 ! jaw morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001708 ! inheres in jaw skeleton relationship: RO:0000052 UBERON:0001708 ! inheres in jaw skeleton [Term] id: OBA:0003742 name: anatomical system position def: "The position of a anatomical system." [AUTO:patterns/patterns/entity_attribute] synonym: "position of anatomical system" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0015074 ! organ system trait is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0000467 ! inheres in anatomical system [Term] id: OBA:0003754 name: skeletal joint morphology def: "The morphology of a skeletal joint." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of skeletal joint" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0002932 ! joint morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0000982 ! characteristic of part of skeletal joint relationship: RO:0002314 UBERON:0000982 ! characteristic of part of skeletal joint [Term] id: OBA:0003760 name: cervical vertebra morphology def: "The morphology of a cervical vertebra." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of cervical vertebra" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0005710 ! neck morphology is_a: OBA:1000660 ! trunk or cervical vertebra quality is_a: OBA:VT0000137 ! vertebra morphology trait is_a: OBA:VT0002114 ! axial skeleton morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0002413 ! characteristic of part of cervical vertebra relationship: RO:0002314 UBERON:0002413 ! characteristic of part of cervical vertebra [Term] id: OBA:0003763 name: metacarpal bone morphology def: "The morphology of a metacarpal bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of metacarpal bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0003073 ! metacarpus morphology trait is_a: OBA:VT0010104 ! forelimb long bone morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0002374 ! characteristic of part of metacarpal bone relationship: RO:0002314 UBERON:0002374 ! characteristic of part of metacarpal bone [Term] id: OBA:0003917 name: chest morphology def: "The morphology of a chest." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of chest" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0004134 ! thorax morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001443 ! characteristic of part of relationship: RO:0002314 UBERON:0001443 ! characteristic of part of [Term] id: OBA:0003980 name: supraoccipital bone size def: "The size of a supraoccipital bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of supraoccipital bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000138 ! bone element size is_a: OBA:VT0000078 ! supraoccipital bone morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0004747 ! inheres in supraoccipital bone relationship: RO:0000052 UBERON:0004747 ! inheres in supraoccipital bone [Term] id: OBA:0004002 name: shoulder bone morphology def: "The morphology of a shoulder bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of shoulder bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003695 ! bone of appendage girdle complex morphology intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003461 ! characteristic of part of shoulder bone relationship: RO:0002314 UBERON:0003461 ! characteristic of part of shoulder bone [Term] id: OBA:0004026 name: vertebral bone 1 morphology def: "The morphology of a vertebral bone 1." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of vertebral bone 1" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001092 ! characteristic of part of vertebral bone 1 relationship: RO:0002314 UBERON:0001092 ! characteristic of part of vertebral bone 1 [Term] id: OBA:0004027 name: vertebral bone 2 morphology def: "The morphology of a vertebral bone 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of vertebral bone 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001093 ! characteristic of part of vertebral bone 2 relationship: RO:0002314 UBERON:0001093 ! characteristic of part of vertebral bone 2 [Term] id: OBA:0004029 name: trochanter morphology def: "The morphology of a trochanter." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of trochanter" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000559 ! femur morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0000980 ! characteristic of part of trochanter relationship: RO:0002314 UBERON:0000980 ! characteristic of part of trochanter [Term] id: OBA:0004033 name: metatarsal bone length def: "The length of a metatarsal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: FOVT:0001141 ! metapodial bone length is_a: OBA:0002251 ! metatarsal bone size intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001448 ! inheres in metatarsal bone [Term] id: OBA:0004048 name: lumbar vertebra length def: "The length of a lumbar vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "length of lumbar vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002414 ! inheres in lumbar vertebra [Term] id: OBA:0004075 name: incisor tooth length def: "The length of a incisor tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "length of incisor tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000113 ! incisor size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001098 ! inheres in incisor tooth [Term] id: OBA:0004154 name: olfactory system morphology def: "The morphology of a olfactory system." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of olfactory system" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0005725 ! characteristic of part of olfactory system relationship: RO:0002314 UBERON:0005725 ! characteristic of part of olfactory system [Term] id: OBA:0004155 name: skeletal system morphology def: "The morphology of a skeletal system." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of skeletal system" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001434 ! characteristic of part of skeletal system relationship: RO:0002314 UBERON:0001434 ! characteristic of part of skeletal system [Term] id: OBA:0004257 name: molar tooth size def: "The size of a molar tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "size of molar tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000112 ! tooth size is_a: OBA:VT0002689 ! molar morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0003655 ! inheres in molar tooth relationship: RO:0000052 UBERON:0003655 ! inheres in molar tooth [Term] id: OBA:0004448 name: cranium height def: "The height of a cranium." [AUTO:patterns/patterns/entity_attribute] synonym: "height of cranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010613 ! cranium size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: RO:0000052 UBERON:0003128 ! inheres in cranium [Term] id: OBA:0004552 name: vagina mass def: "The mass of a vagina." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of vagina" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000213 ! female reproductive system quality is_a: OBA:2045413 ! anatomical entity mass intersection_of: PATO:0000125 ! mass intersection_of: RO:0000052 UBERON:0000996 ! inheres in vagina relationship: RO:0000052 UBERON:0000996 ! inheres in vagina [Term] id: OBA:0004592 name: pedal digit 1 morphology def: "The morphology of a pedal digit 1." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of pedal digit 1" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000314 ! pedal digit quality is_a: OBA:VT0000556 ! hindlimb morphology trait is_a: OBA:VT0002110 ! digit morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003631 ! characteristic of part of pedal digit 1 relationship: RO:0002314 UBERON:0003631 ! characteristic of part of pedal digit 1 [Term] id: OBA:0004643 name: male reproductive organ morphology def: "The morphology of a male reproductive organ." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of male reproductive organ" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0001145 ! male reproductive system morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003135 ! characteristic of part of male reproductive organ relationship: RO:0002314 UBERON:0003135 ! characteristic of part of male reproductive organ [Term] id: OBA:0004650 name: female reproductive organ morphology def: "The morphology of a female reproductive organ." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of female reproductive organ" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0001119 ! female reproductive system morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003134 ! characteristic of part of female reproductive organ relationship: RO:0002314 UBERON:0003134 ! characteristic of part of female reproductive organ [Term] id: OBA:0004651 name: internal female genitalia morphology def: "The morphology of a internal female genitalia." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of internal female genitalia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0004650 ! female reproductive organ morphology intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003975 ! characteristic of part of internal female genitalia relationship: RO:0002314 UBERON:0003975 ! characteristic of part of internal female genitalia [Term] id: OBA:0004725 name: embryo mass def: "The mass of a embryo." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of embryo" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000069 ! embryo trait is_a: OBA:VT0001259 ! body mass intersection_of: PATO:0000125 ! mass intersection_of: RO:0000052 UBERON:0000922 ! inheres in embryo [Term] id: OBA:0004782 name: pubic symphysis morphology def: "The morphology of a pubic symphysis." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of pubic symphysis" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003754 ! skeletal joint morphology is_a: OBA:VT0010088 ! pubis morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003699 ! characteristic of part of pubic symphysis relationship: RO:0002314 UBERON:0003699 ! characteristic of part of pubic symphysis [Term] id: OBA:0004840 name: navicular bone of pes morphology def: "The morphology of a navicular bone of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of navicular bone of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0002810 ! tarsal bone morphology is_a: OBA:1000189 ! navicular bone of pes quality intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001451 ! characteristic of part of navicular bone of pes [Term] id: OBA:0004895 name: palate bone size def: "The size of a palate bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of palate bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000065 ! dermal bone morphology is_a: OBA:1000138 ! bone element size is_a: OBA:VT0002116 ! craniofacial bone morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0012071 ! inheres in palate bone relationship: RO:0000052 UBERON:0012071 ! inheres in palate bone [Term] id: OBA:0004900 name: vomer size def: "The size of a vomer." [AUTO:patterns/patterns/entity_attribute] synonym: "size of vomer" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0004895 ! palate bone size is_a: OBA:VT0000098 ! vomer bone morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0002396 ! inheres in vomer relationship: RO:0000052 UBERON:0002396 ! inheres in vomer [Term] id: OBA:0004993 name: fused sacrum morphology def: "The morphology of a fused sacrum." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of fused sacrum" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0002114 ! axial skeleton morphology trait is_a: OBA:VT0010003 ! bone morphology trait is_a: OBA:VT0010086 ! vertebral column morphology trait is_a: OBA:VT1000739 ! rump morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003690 ! characteristic of part of fused sacrum relationship: RO:0002314 UBERON:0003690 ! characteristic of part of fused sacrum [Term] id: OBA:0005188 name: manual digit 1 morphology def: "The morphology of a manual digit 1." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of manual digit 1" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0002110 ! digit morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0001463 ! characteristic of part of manual digit 1 relationship: RO:0002314 UBERON:0001463 ! characteristic of part of manual digit 1 [Term] id: OBA:0005278 name: foramen magnum morphology def: "The morphology of a foramen magnum." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of foramen magnum" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000438 ! skull morphology trait is_a: OBA:VT0010003 ! bone morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003687 ! characteristic of part of foramen magnum relationship: RO:0002314 UBERON:0003687 ! characteristic of part of foramen magnum [Term] id: OBA:0005468 name: limb long bone morphology def: "The morphology of a limb long bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of limb long bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003695 ! bone of appendage girdle complex morphology is_a: OBA:1000066 ! endochondral bone morphology is_a: OBA:VT0002109 ! limb morphology trait is_a: OBA:VT0003723 ! long bone morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0003606 ! characteristic of part of limb long bone relationship: RO:0002314 UBERON:0003606 ! characteristic of part of limb long bone [Term] id: OBA:0005564 name: cranium length def: "The length of a cranium." [AUTO:patterns/patterns/entity_attribute] synonym: "length of cranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010613 ! cranium size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0003128 ! inheres in cranium [Term] id: OBA:0005710 name: neck morphology def: "The morphology of a neck." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of neck" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0100003 ! organism subdivision trait is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0000974 ! characteristic of part of neck relationship: RO:0002314 UBERON:0000974 ! characteristic of part of neck [Term] id: OBA:0005755 name: tail position def: "The position of a tail." [AUTO:patterns/patterns/entity_attribute] synonym: "position of tail" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100003 ! organism subdivision trait is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0002415 ! inheres in tail relationship: RO:0000052 UBERON:0002415 ! inheres in tail [Term] id: OBA:0005862 name: exocrine gland morphology def: "The morphology of a exocrine gland." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of exocrine gland" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0002163 ! gland morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0002365 ! characteristic of part of exocrine gland relationship: RO:0002314 UBERON:0002365 ! characteristic of part of exocrine gland [Term] id: OBA:0006029 name: horn size def: "The size of a horn." [AUTO:patterns/patterns/entity_attribute] synonym: "size of horn" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:0006030 ! horn morphology intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0006967 ! inheres in horn relationship: RO:0000052 UBERON:0006967 ! inheres in horn [Term] id: OBA:0006030 name: horn morphology def: "The morphology of a horn." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of horn" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000432 ! head morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0006967 ! characteristic of part of horn relationship: RO:0002314 UBERON:0006967 ! characteristic of part of horn [Term] id: OBA:0100002 name: biological process attribute namespace: oba def: "The quality of a biological process." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of biological process" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0000001 {is_asserted="true"} ! biological attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 GO:0008150 ! characteristic of part of biological process relationship: RO:0002314 GO:0008150 ! characteristic of part of biological process [Term] id: OBA:0100003 name: anatomical entity attribute namespace: oba def: "The quality of a anatomical entity." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of anatomical entity" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0000001 {is_asserted="true"} ! biological attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001062 ! characteristic of part of anatomical entity relationship: RO:0002314 UBERON:0001062 ! characteristic of part of anatomical entity [Term] id: OBA:1000030 name: upper arm circumference namespace: oba def: "The circumference of a forelimb stylopod." [AUTO:patterns/patterns/entity_attribute] synonym: "circumference of forelimb stylopod" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "forelimb stylopod circumference trait" EXACT [GOC:TermGenie] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0003854 ! forelimb stylopod morphology trait is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0003822 ! inheres in forelimb stylopod relationship: RO:0000052 UBERON:0003822 ! inheres in forelimb stylopod created_by: cjmungall creation_date: 2013-06-17T17:53:31Z [Term] id: OBA:1000031 name: neck circumference namespace: oba def: "The circumference of a neck." [AUTO:patterns/patterns/entity_attribute] synonym: "circumference of neck" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "neck circumference trait" EXACT [GOC:TermGenie] is_a: OBA:0002103 ! neck size is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0000974 ! inheres in neck created_by: cjmungall creation_date: 2013-06-17T17:53:34Z [Term] id: OBA:1000033 name: upper leg circumference namespace: oba def: "The circumference of a hindlimb stylopod." [AUTO:patterns/patterns/entity_attribute] synonym: "circumference of hindlimb stylopod" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "hindlimb stylopod circumference trait" EXACT [GOC:TermGenie] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0003856 ! hindlimb stylopod morphology trait is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: RO:0000052 UBERON:0000376 ! inheres in hindlimb stylopod relationship: RO:0000052 UBERON:0000376 ! inheres in hindlimb stylopod created_by: cjmungall creation_date: 2013-06-17T17:53:39Z [Term] id: OBA:1000048 name: manus length namespace: oba def: "The length of a manus." [AUTO:patterns/patterns/entity_attribute] synonym: "hand length" EXACT [] synonym: "length of manus" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "manus length trait" EXACT [GOC:TermGenie] is_a: OBA:0002188 ! manus size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002398 ! inheres in manus created_by: cjmungall creation_date: 2014-01-27T23:51:00Z [Term] id: OBA:1000049 name: pes length namespace: oba def: "The length of a pes." [AUTO:patterns/patterns/entity_attribute] synonym: "foot length" EXACT [] synonym: "hindfoot length" EXACT [] synonym: "length of pes" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "pes length trait" EXACT [GOC:TermGenie] is_a: OBA:VT0000573 ! hind paw size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0002387 ! inheres in pes relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 created_by: cjmungall creation_date: 2014-01-27T23:51:06Z [Term] id: OBA:1000057 name: gland quality namespace: oba def: "The quality of a gland." [obo:oba/patterns/entity_attribute_part_of] synonym: "gland quality trait" EXACT [GOC:TermGenie] synonym: "quality of gland" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0002530 ! characteristic of part of gland relationship: RO:0002314 UBERON:0002530 ! characteristic of part of gland created_by: cjmungall creation_date: 2014-02-02T00:49:38Z [Term] id: OBA:1000064 name: dermal bone quality namespace: oba def: "The quality of a dermal bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "dermal bone quality trait" EXACT [GOC:TermGenie] synonym: "quality of dermal bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0008907 ! characteristic of part of dermal bone relationship: RO:0002314 UBERON:0008907 ! characteristic of part of dermal bone created_by: cjmungall creation_date: 2014-02-22T16:19:16Z [Term] id: OBA:1000065 name: dermal bone morphology namespace: oba def: "The morphology of a dermal bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "dermal bone morphology trait" EXACT [GOC:TermGenie] synonym: "morphology of dermal bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000064 ! dermal bone quality is_a: OBA:VT0010003 ! bone morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0008907 ! characteristic of part of dermal bone created_by: cjmungall creation_date: 2014-02-22T16:24:50Z [Term] id: OBA:1000066 name: endochondral bone morphology namespace: oba def: "The morphology of a endochondral bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "endochondral bone morphology trait" EXACT [GOC:TermGenie] synonym: "morphology of endochondral bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:VT0010003 ! bone morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: RO:0002314 UBERON:0002513 ! characteristic of part of endochondral bone created_by: cjmungall creation_date: 2014-02-22T16:24:56Z [Term] id: OBA:1000067 name: endochondral bone quality namespace: oba def: "The quality of a endochondral bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "endochondral bone quality trait" EXACT [GOC:TermGenie] synonym: "quality of endochondral bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0002513 ! characteristic of part of endochondral bone relationship: RO:0002314 UBERON:0002513 ! characteristic of part of endochondral bone created_by: cjmungall creation_date: 2014-02-22T16:25:02Z [Term] id: OBA:1000099 name: appendage trait namespace: oba def: "The quality of a appendage." [obo:oba/patterns/entity_attribute_part_of] synonym: "appendage quality trait" EXACT [GOC:TermGenie] synonym: "quality of appendage" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0100003 ! organism subdivision trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0000026 ! characteristic of part of appendage relationship: RO:0002314 UBERON:0000026 ! characteristic of part of appendage created_by: cjmungall creation_date: 2014-07-07T02:17:51Z [Term] id: OBA:1000101 name: axial skeleton plus cranial skeleton length namespace: oba def: "The length of a axial skeleton plus cranial skeleton." [AUTO:patterns/patterns/entity_attribute] synonym: "axial skeleton plus cranial skeleton length trait" EXACT [GOC:TermGenie] synonym: "length of axial skeleton plus cranial skeleton" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003443 ! axial skeleton plus cranial skeleton size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0005944 ! inheres in axial skeleton plus cranial skeleton created_by: cjmungall creation_date: 2014-07-07T02:21:22Z [Term] id: OBA:1000102 name: vertebral column length namespace: oba def: "The length of a vertebral column." [AUTO:patterns/patterns/entity_attribute] synonym: "length of vertebral column" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "vertebral column length trait" EXACT [GOC:TermGenie] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0010086 ! vertebral column morphology trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: RO:0000052 UBERON:0001130 ! inheres in vertebral column relationship: RO:0000052 UBERON:0001130 ! inheres in vertebral column created_by: cjmungall creation_date: 2014-07-07T02:21:25Z [Term] id: OBA:1000107 name: testis position namespace: oba def: "The position of a testis." [AUTO:patterns/patterns/entity_attribute] synonym: "position of testis" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "testis position trait" EXACT [GOC:TermGenie] is_a: OBA:1000521 ! male reproductive system attribute is_a: PATO:0000140 intersection_of: PATO:0000140 intersection_of: RO:0000052 UBERON:0000473 ! inheres in testis relationship: RO:0000052 UBERON:0000473 ! inheres in testis created_by: cjmungall creation_date: 2014-07-15T22:55:29Z [Term] id: OBA:1000112 name: tooth size namespace: oba def: "The size of a calcareous tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "calcareous tooth size trait" EXACT [GOC:TermGenie] synonym: "size of calcareous tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0002100 ! tooth morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001091 ! inheres in calcareous tooth relationship: RO:0000052 UBERON:0001091 ! inheres in calcareous tooth created_by: cjmungall creation_date: 2014-07-27T01:19:07Z [Term] id: OBA:1000113 name: incisor size namespace: oba def: "The size of a incisor tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "incisor tooth size trait" EXACT [GOC:TermGenie] synonym: "size of incisor tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000112 ! tooth size is_a: OBA:VT0005358 ! incisor morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001098 ! inheres in incisor tooth relationship: RO:0000052 UBERON:0001098 ! inheres in incisor tooth created_by: cjmungall creation_date: 2014-07-27T01:19:11Z [Term] id: OBA:1000138 name: bone element size namespace: oba def: "The size of a bone element." [AUTO:patterns/patterns/entity_attribute] synonym: "bone element size trait" EXACT [GOC:TermGenie] synonym: "size of bone element" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0000015 ! anatomical structure size is_a: OBA:VT0010003 ! bone morphology trait intersection_of: PATO:0000117 ! size intersection_of: RO:0000052 UBERON:0001474 ! inheres in bone element relationship: RO:0000052 UBERON:0001474 ! inheres in bone element created_by: cjmungall creation_date: 2015-03-03T00:34:47Z [Term] id: OBA:1000148 name: proximal epiphysis of tibia quality def: "The quality of a proximal epiphysis of tibia." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal epiphysis of tibia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000340 ! tibia quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0008772 ! characteristic of part of proximal epiphysis of tibia relationship: RO:0002314 UBERON:0008772 ! characteristic of part of proximal epiphysis of tibia [Term] id: OBA:1000150 name: proximal phalanx of manual digit 5 quality def: "The quality of a proximal phalanx of manual digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004331 ! characteristic of part of proximal phalanx of manual digit 5 relationship: RO:0002314 UBERON:0004331 ! characteristic of part of proximal phalanx of manual digit 5 [Term] id: OBA:1000158 name: manual digit 4 phalanx quality def: "The quality of a manual digit 4 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of manual digit 4 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000632 ! phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003638 ! characteristic of part of manual digit 4 phalanx relationship: RO:0002314 UBERON:0003638 ! characteristic of part of manual digit 4 phalanx [Term] id: OBA:1000161 name: pedal digit 1 phalanx quality def: "The quality of a pedal digit 1 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 1 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003640 ! characteristic of part of pedal digit 1 phalanx relationship: RO:0002314 UBERON:0003640 ! characteristic of part of pedal digit 1 phalanx [Term] id: OBA:1000170 name: proximal phalanx of pedal digit 2 quality def: "The quality of a proximal phalanx of pedal digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000353 ! pedal digit 2 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004333 ! characteristic of part of proximal phalanx of pedal digit 2 relationship: RO:0002314 UBERON:0004333 ! characteristic of part of proximal phalanx of pedal digit 2 [Term] id: OBA:1000171 name: forelimb stylopod quality def: "The quality of a forelimb stylopod." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of forelimb stylopod" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000099 ! appendage trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003822 ! characteristic of part of forelimb stylopod relationship: RO:0002314 UBERON:0003822 ! characteristic of part of forelimb stylopod [Term] id: OBA:1000175 name: middle phalanx of pedal digit 5 quality def: "The quality of a middle phalanx of pedal digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000329 ! pedal digit 5 phalanx quality is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004327 ! characteristic of part of middle phalanx of pedal digit 5 relationship: RO:0002314 UBERON:0004327 ! characteristic of part of middle phalanx of pedal digit 5 [Term] id: OBA:1000177 name: ilium quality def: "The quality of a ilium." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of ilium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:VT0100003 ! organism subdivision trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001273 ! characteristic of part of ilium relationship: RO:0002314 UBERON:0001273 ! characteristic of part of ilium [Term] id: OBA:1000178 name: proximal phalanx of manual digit 3 quality def: "The quality of a proximal phalanx of manual digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004329 ! characteristic of part of proximal phalanx of manual digit 3 relationship: RO:0002314 UBERON:0004329 ! characteristic of part of proximal phalanx of manual digit 3 [Term] id: OBA:1000180 name: distal epiphysis of femur quality def: "The quality of a distal epiphysis of femur." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal epiphysis of femur" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000621 ! femur quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004406 ! characteristic of part of distal epiphysis of femur relationship: RO:0002314 UBERON:0004406 ! characteristic of part of distal epiphysis of femur [Term] id: OBA:1000189 name: navicular bone of pes quality def: "The quality of a navicular bone of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of navicular bone of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000508 ! tarsal bone quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001451 ! characteristic of part of navicular bone of pes relationship: RO:0002314 UBERON:0001451 ! characteristic of part of navicular bone of pes [Term] id: OBA:1000190 name: distal phalanx of manus quality def: "The quality of a distal phalanx of manus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000423 ! distal segment of manual digit quality is_a: OBA:1000632 ! phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003865 ! characteristic of part of distal phalanx of manus relationship: RO:0002314 UBERON:0003865 ! characteristic of part of distal phalanx of manus [Term] id: OBA:1000191 name: pedal digit 2 quality def: "The quality of a pedal digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000314 ! pedal digit quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003632 ! characteristic of part of pedal digit 2 relationship: RO:0002314 UBERON:0003632 ! characteristic of part of pedal digit 2 [Term] id: OBA:1000196 name: distal epiphysis of tibia quality def: "The quality of a distal epiphysis of tibia." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal epiphysis of tibia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000340 ! tibia quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004405 ! characteristic of part of distal epiphysis of tibia relationship: RO:0002314 UBERON:0004405 ! characteristic of part of distal epiphysis of tibia [Term] id: OBA:1000204 name: proximal phalanx of manual digit 4 quality def: "The quality of a proximal phalanx of manual digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000158 ! manual digit 4 phalanx quality is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004330 ! characteristic of part of proximal phalanx of manual digit 4 relationship: RO:0002314 UBERON:0004330 ! characteristic of part of proximal phalanx of manual digit 4 [Term] id: OBA:1000205 name: synovial joint quality def: "The quality of a synovial joint." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of synovial joint" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0002217 ! characteristic of part of synovial joint relationship: RO:0002314 UBERON:0002217 ! characteristic of part of synovial joint [Term] id: OBA:1000208 name: middle phalanx of manual digit 4 quality def: "The quality of a middle phalanx of manual digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of manual digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000158 ! manual digit 4 phalanx quality is_a: OBA:1000382 ! middle phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004322 ! characteristic of part of middle phalanx of manual digit 4 relationship: RO:0002314 UBERON:0004322 ! characteristic of part of middle phalanx of manual digit 4 [Term] id: OBA:1000210 name: distal phalanx of manual digit 3 quality def: "The quality of a distal phalanx of manual digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004312 ! characteristic of part of distal phalanx of manual digit 3 relationship: RO:0002314 UBERON:0004312 ! characteristic of part of distal phalanx of manual digit 3 [Term] id: OBA:1000212 name: proximal phalanx of pes quality def: "The quality of a proximal phalanx of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003868 ! characteristic of part of proximal phalanx of pes relationship: RO:0002314 UBERON:0003868 ! characteristic of part of proximal phalanx of pes [Term] id: OBA:1000213 name: female reproductive system quality def: "The quality of a female reproductive system." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of female reproductive system" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0000474 ! characteristic of part of female reproductive system relationship: RO:0002314 UBERON:0000474 ! characteristic of part of female reproductive system [Term] id: OBA:1000215 name: proximal phalanx of pedal digit 4 quality def: "The quality of a proximal phalanx of pedal digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000575 ! pedal digit 4 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004335 ! characteristic of part of proximal phalanx of pedal digit 4 relationship: RO:0002314 UBERON:0004335 ! characteristic of part of proximal phalanx of pedal digit 4 [Term] id: OBA:1000228 name: proximal phalanx of manual digit 2 quality def: "The quality of a proximal phalanx of manual digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004328 ! characteristic of part of proximal phalanx of manual digit 2 relationship: RO:0002314 UBERON:0004328 ! characteristic of part of proximal phalanx of manual digit 2 [Term] id: OBA:1000240 name: proximal phalanx of pedal digit 5 quality def: "The quality of a proximal phalanx of pedal digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000329 ! pedal digit 5 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004336 ! characteristic of part of proximal phalanx of pedal digit 5 relationship: RO:0002314 UBERON:0004336 ! characteristic of part of proximal phalanx of pedal digit 5 [Term] id: OBA:1000249 name: basicranium quality def: "The quality of a basicranium." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of basicranium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000429 ! skull quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0002517 ! characteristic of part of basicranium relationship: RO:0002314 UBERON:0002517 ! characteristic of part of basicranium [Term] id: OBA:1000254 name: metatarsal bone of digit 5 quality def: "The quality of a metatarsal bone of digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of metatarsal bone of digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:1000099 ! appendage trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003654 ! characteristic of part of metatarsal bone of digit 5 relationship: RO:0002314 UBERON:0003654 ! characteristic of part of metatarsal bone of digit 5 [Term] id: OBA:1000269 name: pedal digit 4 quality def: "The quality of a pedal digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000314 ! pedal digit quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003634 ! characteristic of part of pedal digit 4 relationship: RO:0002314 UBERON:0003634 ! characteristic of part of pedal digit 4 [Term] id: OBA:1000271 name: distal phalanx of manual digit 5 quality def: "The quality of a distal phalanx of manual digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004314 ! characteristic of part of distal phalanx of manual digit 5 relationship: RO:0002314 UBERON:0004314 ! characteristic of part of distal phalanx of manual digit 5 [Term] id: OBA:1000283 name: distal phalanx of pedal digit 5 quality def: "The quality of a distal phalanx of pedal digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000329 ! pedal digit 5 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004319 ! characteristic of part of distal phalanx of pedal digit 5 relationship: RO:0002314 UBERON:0004319 ! characteristic of part of distal phalanx of pedal digit 5 [Term] id: OBA:1000291 name: distal phalanx of manual digit 4 quality def: "The quality of a distal phalanx of manual digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000158 ! manual digit 4 phalanx quality is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004313 ! characteristic of part of distal phalanx of manual digit 4 relationship: RO:0002314 UBERON:0004313 ! characteristic of part of distal phalanx of manual digit 4 [Term] id: OBA:1000297 name: pedal digit 5 quality def: "The quality of a pedal digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000314 ! pedal digit quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003635 ! characteristic of part of pedal digit 5 relationship: RO:0002314 UBERON:0003635 ! characteristic of part of pedal digit 5 [Term] id: OBA:1000298 name: thoracic region of vertebral column quality def: "The quality of a thoracic region of vertebral column." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of thoracic region of vertebral column" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0015059 ! thorax trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0006073 ! characteristic of part of thoracic region of vertebral column relationship: RO:0002314 UBERON:0006073 ! characteristic of part of thoracic region of vertebral column [Term] id: OBA:1000299 name: middle phalanx of pedal digit 4 quality def: "The quality of a middle phalanx of pedal digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000492 ! middle phalanx of pes quality is_a: OBA:1000575 ! pedal digit 4 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004326 ! characteristic of part of middle phalanx of pedal digit 4 relationship: RO:0002314 UBERON:0004326 ! characteristic of part of middle phalanx of pedal digit 4 [Term] id: OBA:1000300 name: ulna quality def: "The quality of a ulna." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of ulna" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:1000099 ! appendage trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001424 ! characteristic of part of ulna relationship: RO:0002314 UBERON:0001424 ! characteristic of part of ulna [Term] id: OBA:1000304 name: proximal epiphysis of radius quality def: "The quality of a proximal epiphysis of radius." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal epiphysis of radius" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000591 ! radius bone quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004413 ! characteristic of part of proximal epiphysis of radius relationship: RO:0002314 UBERON:0004413 ! characteristic of part of proximal epiphysis of radius [Term] id: OBA:1000314 name: pedal digit quality def: "The quality of a pedal digit." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000577 ! digit quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001466 ! characteristic of part of pedal digit relationship: RO:0002314 UBERON:0001466 ! characteristic of part of pedal digit [Term] id: OBA:1000325 name: distal phalanx of manual digit 2 quality def: "The quality of a distal phalanx of manual digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004311 ! characteristic of part of distal phalanx of manual digit 2 relationship: RO:0002314 UBERON:0004311 ! characteristic of part of distal phalanx of manual digit 2 [Term] id: OBA:1000326 name: humerus quality def: "The quality of a humerus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of humerus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:1000171 ! forelimb stylopod quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0000976 ! characteristic of part of humerus relationship: RO:0002314 UBERON:0000976 ! characteristic of part of humerus [Term] id: OBA:1000328 name: distal phalanx of pedal digit 3 quality def: "The quality of a distal phalanx of pedal digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000378 ! pedal digit 3 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004317 ! characteristic of part of distal phalanx of pedal digit 3 relationship: RO:0002314 UBERON:0004317 ! characteristic of part of distal phalanx of pedal digit 3 [Term] id: OBA:1000329 name: pedal digit 5 phalanx quality def: "The quality of a pedal digit 5 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 5 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000297 ! pedal digit 5 quality is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003863 ! characteristic of part of pedal digit 5 phalanx relationship: RO:0002314 UBERON:0003863 ! characteristic of part of pedal digit 5 phalanx [Term] id: OBA:1000334 name: acetabular part of hip bone quality def: "The quality of a acetabular part of hip bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of acetabular part of hip bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000177 ! ilium quality is_a: OBA:1000346 ! hip joint quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001269 ! characteristic of part of acetabular part of hip bone relationship: RO:0002314 UBERON:0001269 ! characteristic of part of acetabular part of hip bone [Term] id: OBA:1000335 name: cuspid quality def: "The quality of a cuspid." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of cuspid" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0100003 ! anatomical entity attribute intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003674 ! characteristic of part of cuspid relationship: RO:0002314 UBERON:0003674 ! characteristic of part of cuspid [Term] id: OBA:1000340 name: tibia quality def: "The quality of a tibia." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of tibia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:1000375 ! hindlimb zeugopod quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0000979 ! characteristic of part of tibia relationship: RO:0002314 UBERON:0000979 ! characteristic of part of tibia [Term] id: OBA:1000346 name: hip joint quality def: "The quality of a hip joint." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of hip joint" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000205 ! synovial joint quality is_a: OBA:VT0100003 ! organism subdivision trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001486 ! characteristic of part of hip joint relationship: RO:0002314 UBERON:0001486 ! characteristic of part of hip joint [Term] id: OBA:1000353 name: pedal digit 2 phalanx quality def: "The quality of a pedal digit 2 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 2 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000191 ! pedal digit 2 quality is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003641 ! characteristic of part of pedal digit 2 phalanx relationship: RO:0002314 UBERON:0003641 ! characteristic of part of pedal digit 2 phalanx [Term] id: OBA:1000375 name: hindlimb zeugopod quality def: "The quality of a hindlimb zeugopod." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of hindlimb zeugopod" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000099 ! appendage trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003823 ! characteristic of part of hindlimb zeugopod relationship: RO:0002314 UBERON:0003823 ! characteristic of part of hindlimb zeugopod [Term] id: OBA:1000378 name: pedal digit 3 phalanx quality def: "The quality of a pedal digit 3 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 3 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000446 ! pedal digit 3 quality is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003642 ! characteristic of part of pedal digit 3 phalanx relationship: RO:0002314 UBERON:0003642 ! characteristic of part of pedal digit 3 phalanx [Term] id: OBA:1000380 name: diaphysis of radius quality def: "The quality of a diaphysis of radius." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of diaphysis of radius" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000552 ! diaphysis quality is_a: OBA:1000591 ! radius bone quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001028 ! characteristic of part of diaphysis of radius relationship: RO:0002314 UBERON:0001028 ! characteristic of part of diaphysis of radius [Term] id: OBA:1000382 name: middle phalanx of manus quality def: "The quality of a middle phalanx of manus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of manus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000632 ! phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003864 ! characteristic of part of middle phalanx of manus relationship: RO:0002314 UBERON:0003864 ! characteristic of part of middle phalanx of manus [Term] id: OBA:1000389 name: middle phalanx of pedal digit 2 quality def: "The quality of a middle phalanx of pedal digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000353 ! pedal digit 2 phalanx quality is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004324 ! characteristic of part of middle phalanx of pedal digit 2 relationship: RO:0002314 UBERON:0004324 ! characteristic of part of middle phalanx of pedal digit 2 [Term] id: OBA:1000394 name: proximal epiphysis of humerus quality def: "The quality of a proximal epiphysis of humerus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal epiphysis of humerus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000326 ! humerus quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004411 ! characteristic of part of proximal epiphysis of humerus relationship: RO:0002314 UBERON:0004411 ! characteristic of part of proximal epiphysis of humerus [Term] id: OBA:1000409 name: glenoid fossa quality def: "The quality of a glenoid fossa." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of glenoid fossa" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0100003 ! organism subdivision trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0006657 ! characteristic of part of glenoid fossa relationship: RO:0002314 UBERON:0006657 ! characteristic of part of glenoid fossa [Term] id: OBA:1000413 name: metatarsal bone of digit 3 quality def: "The quality of a metatarsal bone of digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of metatarsal bone of digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:1000099 ! appendage trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0003652 ! characteristic of part of metatarsal bone of digit 3 relationship: RO:0002314 UBERON:0003652 ! characteristic of part of metatarsal bone of digit 3 [Term] id: OBA:1000416 name: ischium quality def: "The quality of a ischium." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of ischium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000067 ! endochondral bone quality is_a: OBA:VT0100003 ! organism subdivision trait intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0001274 ! characteristic of part of ischium relationship: RO:0002314 UBERON:0001274 ! characteristic of part of ischium [Term] id: OBA:1000419 name: middle phalanx of pedal digit 3 quality def: "The quality of a middle phalanx of pedal digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000378 ! pedal digit 3 phalanx quality is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004325 ! characteristic of part of middle phalanx of pedal digit 3 relationship: RO:0002314 UBERON:0004325 ! characteristic of part of middle phalanx of pedal digit 3 [Term] id: OBA:1000422 name: proximal phalanx of pedal digit 3 quality def: "The quality of a proximal phalanx of pedal digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000378 ! pedal digit 3 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004334 ! characteristic of part of proximal phalanx of pedal digit 3 relationship: RO:0002314 UBERON:0004334 ! characteristic of part of proximal phalanx of pedal digit 3 [Term] id: OBA:1000423 name: distal segment of manual digit quality def: "The quality of a distal segment of manual digit." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal segment of manual digit" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000577 ! digit quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0009552 ! characteristic of part of distal segment of manual digit relationship: RO:0002314 UBERON:0009552 ! characteristic of part of distal segment of manual digit [Term] id: OBA:1000427 name: distal phalanx of pedal digit 2 quality def: "The quality of a distal phalanx of pedal digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000353 ! pedal digit 2 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: RO:0002314 UBERON:0004316 ! characteristic of part of distal phalanx of pedal digit 2 relationship: RO:0002314 UBERON:0004316 ! characteristic of part of distal phalanx of pedal digit 2 [Term] id: OBA:1000429 name: skull quality def: "The quality of a skull." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of skull" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0005382 ! head trait intersection_