# Galaxy MCP Server This project provides a Model Context Protocol (MCP) server for interacting with the Galaxy bioinformatics platform. It enables AI assistants and other clients to connect to Galaxy instances, search and execute tools, manage workflows, and access other features of the Galaxy ecosystem. ## Project Overview The repository holds two independent implementations of the same Galaxy operation set, and the contract that keeps them in step: - [`python/`](python/) -- the Python MCP server, published to PyPI as `galaxy-mcp`. It reaches Galaxy through BioBlend. See the [Python README](python/README.md). - [`typescript/`](typescript/) -- a pnpm workspace published to npm as `@galaxyproject/galaxy-ops`, `galaxy-cli` and `galaxy-mcp`: one framework-free core (`galaxy-ops`) with a command line and a stdio MCP server on top. See the [TypeScript README](typescript/README.md). - [`contract/`](contract/) -- what both are held to: the Python surface manifest, golden results replayed through both, the snapshot of Galaxy's built-in server, and the registry of known differences. See the [contract README](contract/README.md). The two are meant to stay in step: an operation keeps its name and its meaning across both. They are still separate codebases with separate release trains, though, so each README lists the operations that surface actually has -- read the one you are using. [ROADMAP.md](ROADMAP.md) explains why there are two implementations, how they relate to Galaxy's built-in MCP server, and what comes next. [PARITY.md](PARITY.md) is the generated, CI-checked record of where they differ. ## Key Features - **Galaxy Connection**: Connect to any Galaxy instance with a URL and API key - **OAuth Login (optional)**: Offer browser-based sign-in that exchanges credentials for temporary Galaxy API keys - **Server Information**: Retrieve comprehensive server details including version, configuration, and capabilities - **Tools Management**: Search the tool catalog, inspect a tool's inputs, and execute Galaxy tools - **User-Defined Tools**: Create, list, run, and deactivate unprivileged user-defined tools - **Workflow Integration**: Find and import workflows from the Intergalactic Workflow Commission (IWC), then invoke them and follow their invocations - **History Operations**: Manage Galaxy histories, datasets, and collections, and inspect the jobs behind them - **File Management**: Upload files to Galaxy from local storage or from a URL, and download results back - **Pages**: Read and write Galaxy-flavored markdown pages -- history-attached notebooks and standalone reports -- including their revision history - **Verified Container Recommendation (optional)**: Resolve a real `quay.io/biocontainers` image for a set of conda packages instead of guessing one -- see [Optional extras](#optional-extras) - **Mock-based test suite**: The default suite runs entirely against mocked Galaxy responses, so it needs no server; a separate suite against a live Galaxy is opt-in and skips when no credentials are configured ## Optional extras ### `container-recommend` Enables the `recommend_biocontainer` tool, which resolves a verified `quay.io/biocontainers` image for a set of conda packages. Authoring a user-defined tool means naming a container, and a hallucinated image tag is the most common way a UDT passes validation and then dies at run time with `manifest unknown`. This wraps `galaxy.tool_util.deps.mulled.recommend` -- the same resolver Galaxy's own custom-tool agent uses (added in Galaxy 26.1, galaxyproject/galaxy#22981) -- so the image is checked against quay.io rather than invented. It is an extra rather than a hard dependency because `galaxy-tool-util` pulls in lxml and conda-package-streaming, and every other tool on this server works without it. The tool is **only registered when the extra is installed**, so a stock install simply doesn't advertise it. ```bash uvx --from 'galaxy-mcp[container-recommend]' galaxy-mcp # or, for a local checkout: cd python && uv sync --extra container-recommend ``` The same resolver is also available as a standalone CLI once installed: `mulled-recommend samtools=1.17`. ### `code-mode` Collapses the whole tool catalog into three meta-tools -- `search`, `get_schema`, and `run_galaxy_tool` -- so an agent pays for a tool's schema only when it decides to use it. The extra pulls in `pydantic-monty`, the sandboxed interpreter that runs the submitted code. Without the extra the server still starts, but asking for code mode is an error rather than a silent downgrade. ```bash uvx --from 'galaxy-mcp[code-mode]' galaxy-mcp --discovery-mode code ``` See [Tool discovery mode](python/README.md#tool-discovery-mode-experimental) in the Python README for what the trade-off buys you. ## Quick Start The `galaxy-mcp` CLI ships with both stdio (local) and HTTP transports. Choose the setup that matches your client: ```bash # Stdio transport (default) – great for local development tools uvx galaxy-mcp # HTTP transport with OAuth (for remote/browser clients) # Generate the session secret ONCE (`openssl rand -hex 32`) and store it. Every # restart and every replica must use the same value, or tokens issued earlier -- # or by another replica -- stop decrypting. export GALAXY_URL="https://usegalaxy.org.au/" # Target Galaxy instance export GALAXY_MCP_PUBLIC_URL="https://mcp.example.com" # Public base URL for OAuth redirects export GALAXY_MCP_SESSION_SECRET="" uvx galaxy-mcp --transport streamable-http --host 0.0.0.0 --port 8000 ``` When running over stdio you can provide long-lived credentials via environment variables: ```bash export GALAXY_URL="https://usegalaxy.org/" export GALAXY_API_KEY="your-api-key" ``` For OAuth flows the server exchanges user credentials for short-lived Galaxy API keys on demand, so you typically leave `GALAXY_API_KEY` unset. For non-OAuth HTTP clients, `connect(url=..., api_key=...)` stores Galaxy credentials per MCP session rather than globally, for a URL the operator allowed (`GALAXY_URL` or `GALAXY_MCP_EXTRA_ALLOWED_URLS`). That keeps sessions apart but is not authentication: the HTTP transports bind to `127.0.0.1` by default, refuse to serve a non-loopback address without OAuth unless you pass `--allow-unauthenticated`, and disable the tools that touch the server's filesystem. See [Serving over HTTP](python/README.md#serving-over-http). ### Alternative Installation ```bash # Install from PyPI pip install galaxy-mcp # Run (stdio by default) galaxy-mcp # Or from source using uv cd python uv sync uv run galaxy-mcp --transport streamable-http --port 8000 ``` ## Container Usage Images are published to the GitHub Container Registry as [`ghcr.io/galaxyproject/galaxy-mcp`](https://github.com/galaxyproject/galaxy-mcp/pkgs/container/galaxy-mcp). Use `:latest` (default) or pin a release, e.g. `:1.10.0`. The published image defaults to stdio transport (no HTTP listener): ```bash docker run --rm -it \ -e GALAXY_URL="https://usegalaxy.org/" \ -e GALAXY_API_KEY="your-api-key" \ ghcr.io/galaxyproject/galaxy-mcp ``` For OAuth + HTTP: ```bash # Generate once and keep it -- do NOT inline `openssl rand` here, or each # container start mints a key that invalidates every token issued before it. export GALAXY_MCP_SESSION_SECRET="" docker run --rm -it -p 8000:8000 \ -e GALAXY_URL="https://usegalaxy.org.au/" \ -e GALAXY_MCP_TRANSPORT="streamable-http" \ -e GALAXY_MCP_PUBLIC_URL="https://mcp.example.com" \ -e GALAXY_MCP_SESSION_SECRET \ ghcr.io/galaxyproject/galaxy-mcp ``` ## Connect to Claude Desktop - Ensure that GalaxyMCP runs with `uvx galaxy-mcp` - Add `export GALAXY_URL=https://usegalaxy.org` to your .bashrc (or equiv) - Download and install [claude desktop](https://www.claude.com/download) - Go to Settings -> Developer -> Edit Config - Add this to `claude_desktop_config.json` ``` { "mcpServers": { "galaxy-mcp": { "command": "uvx", "args": ["galaxy-mcp"], "env": { "GALAXY_URL": "https://usegalaxy.org", "GALAXY_API_KEY": "SECRETS" } } } } ``` - Under the developer menu, you should now see `galaxy-mcp` as running (you may need to restart Claude desktop) - Prompt Claude with "can you connect to galaxy" - If you have not provided the optional env config you'll be asked for connection details which you can provide like "Use my Galaxy API key: XXXXXXX" - Talk to Claude to work with your galaxy instance, e.g. "give a summary with my histories" ## Development Guidelines See the [Python implementation README](python/README.md) for specific instructions and documentation. ## License [MIT](LICENSE)