Quantitative and qualitative variables describing ...
INCENTIVE Project Controlled Vocabulary
assay
variable
An analyte assay that measures the presence or amount of antibodies to a specified antigen.
antigen specific antibodies assay
multiplex assay that measures the amount and avidity of a specific IgG subclass to several influenza virus antigens
quantitative suspension multiplex assay to measure IgG subclasses and avidity to influenza virus antigens
A mass spectrometry assay where a sample mixture is first separated by liquid chromatography before being converted into ions which are characterized by using mass spectrometry based on their mass-to-charge ratio and relative abundance.
liquid chromatography mass spectrometry assay
A proteomics profiling assay that detects proteins in a blood plasma specimen.
plasma proteomics assay
An RNA sequencing assay that determines an RNA sequence by analyzing the transcibed regions of the genome and or to quantitate transcript abundance.
RNA-seq assay
A molecular assay that permits the simultaneous measurement of an array of proteins in a single, small volume sample.
multiplex bead-based assay
A type of solid-phase multiplex assay that uses microbeads coated with recombinant or infinity purified antigens from a single allele for the detection and identification of an antibody that would bind and react to this antigen.
singleplex bead-based assay
A cytometry assay in which an input cell population is put in solution, is passed by a laser, and optical sensors are used to detect scattering of the laser light and/or fluorescence of specific markers to count and characterize the particles in solution.
flow cytometry assay
An analyte assay in which a series of beads coated with antibodies, antigens, or other small molecules are used to detect an analyte of interest.
cytometric bead array assay
subject
antibody crossreactivity between vaccine antigens
functionality of vaccine induced antibodies
antibodies as biomarkers of vaccine protection
A substance used as an indicator of a biological state.
biomarker
A marked decrease in contrast enhancement that is not due to actual tumor shrinkage, but that may be due to immunotherapy.
immunoresponse
The mechanism by which a pharmacologically active substance produces an effect on a living organism or in a biochemical system.
mechanism of action
vaccine response evaluation
biomarker links pre-vaccination response to vaccine response
A microbial phenotype that is observed at the level of an individual cell. This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we recommend that it not be used for direct annotation. Please consider using a more specific term to annotate each phenotype.
cell phenotype
The functionality of a cell.
cell functionality
levels of immunoglobulin 1 against recombinant hemaglutionin from the strain A/California/04/2009 wt rHA H1 7871
levels IgG1-rHA_C
levels of immunoglobulin 1 against recombinant hemaglutionin from the strain A/California/04/2009 wt rHA H1 7871 with urea
levels IgG1-rHA_C with urea
avidity of immunoglobulin 1 against recombinant hemaglutionin from the strain A/California/04/2009 wt rHA H1 7871
avidity levels IgG1-rHA_C
levels of immunoglobulin 1 against recombinant hemaglutionin from the strain A/Brisbane/02/2018 wt rHA H1 20235
levels IgG1-rHA_B
levels of immunoglobulin 1 against recombinant hemaglutionin from the strain A/Brisbane/02/2018 wt rHA H1 20235 with urea
levels IgG1-rHA_B with urea
avidity of immunoglobulin 1 against recombinant hemaglutionin from the strain A/Brisbane/02/2018 wt rHA H1 20235
avidity levels IgG1-rHA_B
relative concentration of lipids in plasma
absolute concentration of metablites in plasma
relative concentration of proteins in plasma
count of reads of RNAs
corrected P-value of RNAs
fold change of RNAs
retention time of lipids in plasma
mass to charge of lipids in plasma
chemical shift of metabolites in plasma
intensity of metabolites in plasma
fluorescence of multiple cytokines with luminex
fluorescence of multiple cytokines with simoa
cytokine concentration
average enzyme per beads
fluorescence intensity of immune cell populations in human blood samples
median fluorescence intensity of antibodies bound to markers on immune cells in human blood samples
frequeny of immune cell populations (phenotype and functionality) in human blood samples
counts of immune cell populations (phenotype and functionality) in human blood samples
fluorescence intensity of antibody bound to soluble factors in human blood samples
mean fluorescence intensity of antibody bound to soluble factors in human blood samples
property
A time interval from the start of chromatography when an analyte exits a chromatographic column.
retention time
retention time of peptides in plasma
mass to charge of peptides in plasma
intensity of peptides in plasma
entity
A protein or polypeptide is a long polymer of amino acids joined together by peptide bonds. The sequence of the amino acids is defined by the genetic code. Here, a protein is a perturbagen whereby its ability to modulate a physiological process or a disease pathology is assessed.
protein
Plasma is the fluid (noncellular) portion of the circulating blood, as distinguished from the serum that is the fluid portion of the blood obtained by removal of the fibrin clot and blood cells after coagulation.
plasma
A compound of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
peptide
The bipedal primate mammal, Homo sapiens; belonging to man or mankind; pertaining to man or to the race of man; use of man as experimental subject or unit of analysis in research.
human
A class of hydrocarbon-containing organic compounds. Lipids are insoluble in water but soluble in nonpolar solvents and play important roles in living organisms: these roles include functioning as energy storage molecules, serving as structural components of cell membranes, and constituting important signaling molecules. Lipids can be subdivided into 2 groups: fatty acids and glycerides.
lipid
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
metabolite
RNA or ribonucleic acid is a polymer of nucleotides with a backbone made of ribose sugar and phosphate groups linked together by ester bonds. RNA has the base uracil instead of thymine, which is present in DNA.
RNA
A liquid tissue; its major function is to transport oxygen throughout the body. It also supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection. Several hormones also travel in the blood.
blood
IgG1-rHA_C
IgG1-rHA_B
IgG2-rHA_C
A class of soluble glycoproteins which act nonenzymatically through specific receptors to regulate immune responses. Cytokines are derived from both immune and non-immune cells and are intercellular mediators that differ from hormones in that they are produced by a number of tissue or cell types rather than by specialized glands.
cytokine
A type of protein made by B lymphocytes in response to a foreign substance (antigen). Each antibody only binds to a specific antigen, helping to destroy the antigen directly or by assisting white blood cells to destroy the antigen.
antibody
Molecules that catalyze a chemical reaction. They are usually proteins, although catalytic RNA and DNA molecules have been identified.
enzyme
a cultured cell population comprised of a single type of immune system cell
cultured immune cell population
Determining the number or amount of something.
count
Fluorescence is a luminescence (i.e., optical phenomenon) in cold bodies, in which a molecule absorbs a high-energy photon, and re-emits it as a lower-energy (longer-wavelength) photon. The energy difference between the absorbed and emitted photons ends up as molecular vibrations (heat).
flourescence
human donor
A unit of measure for the mean fluorescence intensity.
mean fluorescence intensity unit
Frequency is the number of occurrences of a repeating event per unit time
frequency
constraint
A status indicating that an individual has received a vaccination.
vaccinated
A concentration which relatively low.
diluted
A position on a scale measuring intensity, quality, or amount.
level
Showing characteristics of life; displaying signs of life.
alive
concentration of soluble factors in human blood samples
concentration is the amount of substance per unit volume of a solution
concentration