# Hackseq Projects 2016 + [Project 1](https://github.com/hackseq/hackseq_projects_2016/issues/10) Implement an evaluation framework for software that manipulates HGVS-formatted variants + [Project 2](https://github.com/hackseq/hackseq_projects_2016/issues/9) Design a tool to optimize the parameters of any command line tool + [Project 4](https://github.com/hackseq/hackseq_projects_2016/issues/7) Pseudo-WGS variant calling for common cell types aggregating ChIP-seq, RNA-seq and DHS from ENCODE and Roadmap Epigenomics data + [Project 5](https://github.com/hackseq/hackseq_projects_2016/issues/6) A framework to evaluate profiles from DNA-binding site collections represented in peak sequences from ChIP-Seq assays + [Project 6](https://github.com/hackseq/hackseq_projects_2016/issues/5) Inferring sex chromosome and autosomal ploidy in NGS data + [Project 7](https://github.com/hackseq/hackseq_projects_2016/issues/4) Visualization of single cell RNA-seq data from tens of thousands of cells in real time + [Project 8](https://github.com/hackseq/hackseq_projects_2016/issues/3) Explore the use of 10x Genomics' Linked-Reads to unlock currently inaccessible parts of the genome + [Project 9](https://github.com/hackseq/hackseq_projects_2016/issues/2) Selection of tag SNPs for an African SNP array by LD and haplotype based methods + [Project 10](https://github.com/hackseq/hackseq_projects_2016/issues/1) Develop an open-source, automated pipeline to close bacterial genomes with long read technologies