http://purl.obolibrary.org/obo/AISM_0000174 http://purl.obolibrary.org/obo/PATO_0000001 http://purl.obolibrary.org/obo/UBERON_0001062 István Mikó (imiko) https://orcid.org/0000-0003-2938-9075 Jennifer C. Girón (jgiron) https://orcid.org/0000-0002-0851-6883 Luis A. González Montaña (lagonzalezmo) https://orcid.org/0000-0002-9136-9932 Sergei Tarasov (starasov) https://orcid.org/0000-0001-5237-2330 The ontology for the Anatomy of the Insect SkeletoMuscular system (AISM) contains terms used to describe the cuticle - as a single anatomical structure - and the skeletal muscle system, to be used in insect biodiversity research. Ontology for the Anatomy of the Insect SkeletoMuscular system 2023-01-22 This annotation property defines a "sensu", which is the combination of a bibliographic reference, a label and a class (represented by verbatim and logical definitions). Given this model, independent observations can be inferred across to compute synonymy (multiple labels attached to one), homonymy (one label attached to multiple classes). Yoder MJ, Mikó I, Seltmann KC, Bertone MA, Deans AR (2010) A Gross Anatomy Ontology for Hymenoptera. PLOS ONE 5: e15991. https://doi.org/10.1371/journal.pone.0015991.g004 This annotation property is on the label of a class in owl. sensu This annotation property defines a "sensu", which is the combination of a bibliographic reference, a label and a class (represented by verbatim and logical definitions). Given this model, independent observations can be inferred across to compute synonymy (multiple labels attached to one), homonymy (one label attached to multiple classes). Yoder MJ, Mikó I, Seltmann KC, Bertone MA, Deans AR (2010) A Gross Anatomy Ontology for Hymenoptera. PLOS ONE 5: e15991. https://doi.org/10.1371/journal.pone.0015991.g004 This annotation property is on the label of a class in owl. imiko https://orcid.org/0000-0003-2938-9075 2020-11-17 definition The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> definition definition IAO:0000116 uberon editor_note true editor_note editor note editor note curator note An administrative note of use for a curator but of no use for a user PERSON:Alan Ruttenberg IAO:0000232 uberon curator_notes true curator_notes curator note curator note curator notes has ontology root term Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root. Nicolas Matentzoglu IAO:0000700 uberon has_ontology_root_term true has_ontology_root_term has ontology root term has ontology root term preferred_root If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL is a defining property chain axiom If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R. is a defining property chain axiom where second argument is reflexive http://purl.org/dc/elements/1.1/description uberon dc-description true dc-description description http://purl.org/dc/elements/1.1/title uberon dc-title true dc-title title http://purl.org/dc/terms/contributor uberon dc-contributor true dc-contributor contributor A related resource that references, cites, or otherwise points to the described resource. uberon dcterms-isReferencedBy true dcterms-isReferencedBy is referenced by isReferencedBy http://purl.org/dc/terms/license uberon dcterms-license true dcterms-license license Date on which the resource was changed. date_modified subset_property database_cross_reference An alternative label for a class or property which has the exact same meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/20 has exact synonym has_exact_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/20 A preferred label. 2022-03-03 skos:prefLabel X lateral to y if x is further from the midsagittal plane than y. lateral_to X lateral to y if x is further from the midsagittal plane than y. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 lateral_to imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 X medial to y if x is closer to the midsagittal plane than y. medial_to X medial to y if x is closer to the midsagittal plane than y. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 medial_to imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 x encircles y if both x and y are regions of the 2D structure z, or 2D cross-sections of a 3D object z, and the boundary of y on z is exclusively continuous with x. encircles x encircles y if both x and y are regions of the 2D structure z, or 2D cross-sections of a 3D object z, and the boundary of y on z is exclusively continuous with x. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 encircles imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 y is encircled by x if both x and y are regions of the 2D structure z, or 2D cross-sections of a 3D object z, and the boundary of y on z is exclusively continuous with y. encircled by y is encircled by x if both x and y are regions of the 2D structure z, or 2D cross-sections of a 3D object z, and the boundary of y on z is exclusively continuous with y. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 encircled by imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 sclerite A encircles_via_conjunctiva sclerite B if A is encircled_via_conjuntiva X that encircles B encircles via conjunctiva sclerite A encircles_via_conjunctiva sclerite B if A is encircled_via_conjuntiva X that encircles B starasov https://orcid.org/0000-0001-5237-2330 2021-05-31 sclerite B is encircled_via_conjunctiva if sclerite A encircles_via_conjuntiva X sclerite B encircled via conjunctiva sclerite B is encircled_via_conjunctiva if sclerite A encircles_via_conjuntiva X sclerite B jgiron https://orcid.org/0000-0002-0851-6883 2021-06-14 is part of my brain is part of my body (continuant parthood, two material entities) my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity) this day is part of this year (occurrent parthood) a core relation that holds between a part and its whole Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'. part_of BFO:0000050 external protein quality spatial uberon part_of part_of part of part of part_of http://www.obofoundry.org/ro/#OBO_REL:part_of has part my body has part my brain (continuant parthood, two material entities) my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity) this year has part this day (occurrent parthood) a core relation that holds between a whole and its part Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'. has_part BFO:0000051 external protein quality spatial uberon has_part has_part has part has part has_part preceded by x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other. is preceded by preceded_by http://www.obofoundry.org/ro/#OBO_REL:preceded_by BFO:0000062 external uberon preceded_by preceded_by preceded by preceded by precedes x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. BFO:0000063 external uberon precedes precedes precedes precedes occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t occurs_in unfolds in unfolds_in BFO:0000066 external gene_ontology occurs_in occurs_in Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant occurs in occurs in site of [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t BFO:0000067 uberon contains_process contains_process Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant contains process contains process x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. BSPO:0000096 rostral_to spatial uberon anterior_to anterior_to anterior to x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. BSPO:cjm x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal). BSPO:0000097 spatial uberon distal_to distal_to distal to x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal). BSPO:cjm x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). BSPO:0000098 spatial uberon dorsal_to dorsal_to dorsal to x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). BSPO:cjm x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. BSPO:0000099 caudal to spatial uberon posterior_to posterior_to posterior to x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. BSPO:cjm caudal to x proximal to y iff x is closer to the point of attachment with the body than y. BSPO:0000100 spatial uberon proximal_to proximal_to The elbow is proximal to the hand, but distal to the shoulder. proximal to x proximal to y iff x is closer to the point of attachment with the body than y. BSPO:cjm x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). BSPO:0000102 spatial uberon ventral_to ventral_to ventral to x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). BSPO:cjm Crosses at an angle that is 90 degrees, or close to 90 degrees. In any non-linear organism, the main axes are rarely perpendicular when taken through the organism as a whole. BSPO:0000104 spatial approximately_perpendicular_to approximately_perpendicular_to approximately perpendicular to Crosses at an angle that is 90 degrees, or close to 90 degrees. In any non-linear organism, the main axes are rarely perpendicular when taken through the organism as a whole. BSPO:cjm On the opposite side from. For example, the left arm is contralateral to the right arm (and the right leg). BSPO:0000106 spatial contralateral_to contralateral_to contralateral to On the opposite side from. For example, the left arm is contralateral to the right arm (and the right leg). BSPO:cjm Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines. BSPO:0000107 spatial uberon deep_to deep_to deep to Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines. BSPO:cjm Near the outer surface of the organism. Thus, skin is superficial to the muscle layer. BSPO:0000108 spatial uberon superficial_to superficial_to superficial to Near the outer surface of the organism. Thus, skin is superficial to the muscle layer. BSPO:cjm Closer to the left side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is left of some instance y of Y, and there exists some organism o such that x part of o and y part of o. BSPO:0000110 spatial left_of left_of left of Closer to the left side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is left of some instance y of Y, and there exists some organism o such that x part of o and y part of o. BSPO:cjm Closer to the right side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is right of some instance y of Y, and there exists some organism o such that x part of o and y part of o. BSPO:0000111 spatial right_of right_of right of Closer to the right side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is right of some instance y of Y, and there exists some organism o such that x part of o and y part of o. BSPO:cjm Direcly opposite to. i.e. on the opposite side through the axis. BSPO:0000113 spatial opposite_to opposite_to opposite to Direcly opposite to. i.e. on the opposite side through the axis. BSPO:cjm X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion. BSPO:0000120 spatial uberon in_left_side_of in_left_side_of in left side of https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion. BSPO:PATO_mtg_2009 X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion. BSPO:0000121 spatial uberon in_right_side_of in_right_side_of in right side of https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion. BSPO:PATO_mtg_2009 X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion. BSPO:0000122 spatial uberon in_posterior_side_of in_posterior_side_of in posterior side of X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion. BSPO:PATO_mtg_2009 X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion. BSPO:0000123 spatial uberon in_anterior_side_of in_anterior_side_of in anterior side of X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion. BSPO:PATO_mtg_2009 x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion. BSPO:0000124 spatial uberon in_proximal_side_of in_proximal_side_of in proximal side of x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion. BSPO:PATO_mtg_2009 x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion. BSPO:0000125 spatial uberon in_distal_side_of in_distal_side_of in distal side of x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion. BSPO:PATO_mtg_2009 X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure BSPO:0000126 spatial uberon in_lateral_side_of in_lateral_side_of in lateral side of https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure UBERON:cjm x is parallel t y iff x and y are lines or planes which when extended indefinitely do not cross. spatial parallel_to parallel to x is parallel t y iff x and y are lines or planes which when extended indefinitely do not cross. BSPO:curators X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y BSPO:0001106 spatial uberon proximalmost_part_of proximalmost_part_of proximalmost part of X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y https://orcid.org/0000-0002-6601-2165 x immediately deep to y iff x deep_to y and x is contiguous with y. BSPO:0001107 spatial uberon immediately_deep_to immediately_deep_to immediately deep to x immediately deep to y iff x deep_to y and x is contiguous with y. BSPO:curators X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y BSPO:0001108 spatial uberon distalmost_part_of distalmost_part_of distalmost part of X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y https://orcid.org/0000-0002-6601-2165 X intersects median plane of iff X crosses the midine plane of Y. BSPO:0005001 spatial uberon intersects_midsagittal_plane_of intersects_midsagittal_plane_of intersects midsagittal plane of BSPO:0015001 spatial finishes_axis finishes_axis A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. If s finishes axis x, and x has end point p, then x overlaps p finishes axis crossing at right angles BSPO:0015005 spatial orthogonal_to orthogonal_to orthogonal to crossing at right angles BSPO:cjm Intersects at two points. BSPO:0015006 spatial passes_through passes_through passes through Intersects at two points. BSPO:cjm BSPO:0015007 spatial starts_axis starts_axis A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. . If s starts axis x, and x has start point p, then x overlaps p starts axis BSPO:0015008 spatial surface_of surface_of placeholder. used for relation between anatomical surface and an anatomical side. surface of x immediately superficial to y iff x superficial to y and x is contiguous with y. BSPO:0015014 spatial uberon immediately_superficial_to immediately_superficial_to immediately superficial to x immediately superficial to y iff x superficial to y and x is contiguous with y. BSPO:curators X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion. BSPO:0015101 spatial uberon in_dorsal_side_of in_dorsal_side_of in dorsal side of X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion. BSPO:cjm GOREL:0002003 external results_in_distribution_of results_in_distribution_of results in distribution of results_in_distribution_of GOREL:0002004 external results_in_fission_of results_in_fission_of results in fission of results_in_fission_of This document is about information artifacts and their representations A (currently) primitive relation that relates an information artifact to an entity. 7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of "mentions" relation. Weaken the is_about relationship to be primitive. We will try to build it back up by elaborating the various subproperties that are more precisely defined. Some currently missing phenomena that should be considered "about" are predications - "The only person who knows the answer is sitting beside me" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic. person:Alan Ruttenberg Smith, Ceusters, Ruttenberg, 2000 years of philosophy is about A person's name denotes the person. A variable name in a computer program denotes some piece of memory. Lexically equivalent strings can denote different things, for instance "Alan" can denote different people. In each case of use, there is a case of the denotation relation obtaining, between "Alan" and the person that is being named. A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically 2009-11-10 Alan Ruttenberg. Old definition said the following to emphasize the generic nature of this relation. We no longer have 'specifically denotes', which would have been primitive, so make this relation primitive. g denotes r =def r is a portion of reality there is some c that is a concretization of g every c that is a concretization of g specifically denotes r person:Alan Ruttenberg Conversations with Barry Smith, Werner Ceusters, Bjoern Peters, Michel Dumontier, Melanie Courtot, James Malone, Bill Hogan denotes inverse of the relation 'denotes' Person: Jie Zheng, Chris Stoeckert, Mike Conlon denoted by has_specified_output has_specified_output The inverse property of is_specified_output_of PERSON: Alan Ruttenberg PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Courtot has_specified_output is_specified_output_of is_specified_output_of A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. Alan Ruttenberg PERSON:Bjoern Peters is_specified_output_of inheres in this fragility is a characteristic of this vase this red color is a characteristic of this apple a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence. inheres_in RO:0000052 characteristic_of Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing. characteristic of bearer of this apple is bearer of this red color this vase is bearer of this fragility Inverse of characteristic_of A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist. bearer_of is bearer of RO:0000053 external bearer_of bearer_of has_characteristic bearer of has characteristic participates in this blood clot participates in this blood coagulation this input material (or this output material) participates in this process this investigator participates in this investigation a relation between a continuant and a process, in which the continuant is somehow involved in the process participates_in RO:0000056 external uberon participates_in participates_in participates in participates in has participant this blood coagulation has participant this blood clot this investigation has participant this investigator this process has participant this input material (or this output material) a relation between a process and a continuant, in which the continuant is somehow involved in the process Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. has_participant http://www.obofoundry.org/ro/#OBO_REL:has_participant RO:0000057 external has_participant has_participant has participant has participant this catalysis function is a function of this enzyme a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists. function_of is function of RO:0000079 function_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. function of this red color is a quality of this apple a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence A quality inheres in its bearer at all times for which the quality exists. is quality of quality_of RO:0000080 quality_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. quality of this investigator role is a role of this person a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists. is role of role_of RO:0000081 role_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. role of this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function) a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists. has_function RO:0000085 has_function has function this apple has quality this red color a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist. has_quality RO:0000086 protein uberon has_quality false has_quality has quality has quality has_quality this person has role this investigator role (more colloquially: this person has this role of investigator) a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists. has_role RO:0000087 has_role has role a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence RO:0000091 has_disposition has disposition inverse of has disposition RO:0000092 disposition_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. disposition of is location of my head is the location of my brain this cage is the location of this rat a relation between two independent continuants, the location and the target, in which the target is entirely within the location Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ location_of RO:0001015 uberon location_of location_of location of location of contained in Containment is location not involving parthood, and arises only where some immaterial continuant is involved. Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition): Intended meaning: domain: material entity range: spatial region or site (immaterial continuant) contained_in RO:0001018 contained_in contained in contains RO:0001019 uberon contains contains contains contains located in my brain is located in my head this rat is located in this cage a relation between two independent continuants, the target and the location, in which the target is entirely within the location Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ located_in http://www.obofoundry.org/ro/#OBO_REL:located_in RO:0001025 uberon located_in located_in located in located in This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation. This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation. the surface of my skin is a 2D boundary of my body a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts. Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape. 2D_boundary_of boundary of is 2D boundary of is boundary of surface of RO:0002000 2D_boundary_of 2D boundary of boundary_of my body has 2D boundary the surface of my skin a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts. Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape. David Osumi-Sutherland has boundary has_2D_boundary RO:0002002 uberon has_boundary has_2D_boundary has_boundary has 2D boundary has 2D boundary has_boundary David Osumi-Sutherland http://www.ncbi.nlm.nih.gov/pubmed/22402613 RO:0002005 uberon innervated_by innervated_by innervated_by innervated_by X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 David Osumi-Sutherland RO:0002007 external uberon bounding_layer_of bounding_layer_of A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane. bounding layer of bounding layer of A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other. Note from NCEAS meeting: consider changing primary label David Osumi-Sutherland Example: if we define region of chromosome as any subdivision of a chromosome along its long axis, then we can define a region of chromosome that contains only gene x as 'chromosome region' that coincident_with some 'gene x', where the term gene X corresponds to a genomic sequence. coincident with A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. dos 2017-05-24T09:30:46Z RO:0002013 external has_regulatory_component_activity has_regulatory_component_activity has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. dos 2017-05-24T09:31:01Z RO:0002014 external has_negative_regulatory_component_activity has_negative_regulatory_component_activity By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'. has negative regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. dos 2017-05-24T09:31:17Z RO:0002015 has_positive_regulatory_component_activity By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'. has positive regulatory component activity dos 2017-05-24T09:44:33Z RO:0002017 has_component_activity A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B. has component activity w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. dos 2017-05-24T09:49:21Z RO:0002018 has_component_process has component process A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. dos 2017-07-20T17:19:37Z RO:0002021 occurs_across occurs across dos 2017-09-17T13:52:24Z RO:0002022 directly_regulated_by Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. directly regulated by Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. GOC:dos Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. dos 2017-09-17T13:52:38Z RO:0002023 directly_negatively_regulated_by directly negatively regulated by Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. GOC:dos Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. dos 2017-09-17T13:52:47Z RO:0002024 directly_positively_regulated_by directly positively regulated by Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. GOC:dos A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. dos 2017-09-22T14:14:36Z RO:0002025 has_effector_activity This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations. has effector activity A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. GOC:dos David Osumi-Sutherland <= RO:0002081 before_or_simultaneous_with Primitive instance level timing relation between events before or simultaneous with David Osumi-Sutherland RO:0002082 uberon simultaneous_with simultaneous_with t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2) simultaneous with simultaneous with David Osumi-Sutherland RO:0002086 ends_after X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) ends after David Osumi-Sutherland starts_at_end_of RO:0002087 external uberon immediately_preceded_by immediately_preceded_by X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) immediately preceded by immediately preceded by David Osumi-Sutherland ends_at_start_of meets RO:0002090 external immediately_precedes immediately_precedes X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) immediately precedes immediately precedes Relation between a neuron and an anatomical structure that its soma is part of. Relation between a neuron and an anatomical structure that its soma is part of. David Osumi-Sutherland <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0043025> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y) BFO_0000051 some (GO_0043025 and BFO_0000050 some ?Y) RO:0002100 fly_anatomy.ontology has_soma_location has_soma_location has soma location Relation between a neuron and an anatomical structure that its soma is part of. FBC:DOS Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814] Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. Alexander Diehl Chris Mungall Lindsay Cowell <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0005886> and <http://purl.obolibrary.org/obo/BFO_0000051> some ?Y) RO:0002104 has_plasma_membrane_part has plasma membrane part x overlaps y if and only if there exists some z such that x has part z and z part of y x overlaps y iff they have some part in common. http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y) RO:0002131 external spatial uberon overlaps overlaps "(forall (x y) (iff (overlaps x y) (exists (z) (and (part of z x) (part of z y)))))" CLIF [] overlaps overlaps true x overlaps y iff they have some part in common. BSPO:cjm Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. David Osumi-Sutherland <http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?))) RO_0002132 some (GO_0043005 that (RO_0002131 some (GO_0045202 that BFO_0000050 some ?Y))) RO:0002134 fly_anatomy.ontology uberon innervates innervates innervates innervates Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. FBC:DOS X continuous_with Y if and only if X and Y share a fiat boundary. David Osumi-Sutherland connected to The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint) RO:0002150 uberon continuous_with continuous_with continuous with continuous with FMA:85972 lactation SubClassOf 'only in taxon' some 'Mammalia' U only_in_taxon T: U is a feature found in only in organisms of species of taxon T. The feature cannot be found in an organism of any species outside of (not subsumed by) that taxon. Down-propagates in U hierarchy, up-propagates in T hierarchy (species taxonomy). Implies applicable_to_taxon. x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g. 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria Chris Mungall RO:0002160 never_outside_taxon specific_to specific_to_taxon protein uberon only_in_taxon false only_in_taxon Down-propagates. The original name for this in the paper is 'specific_to'. Applicable to genes because some genes are lost in sub-species (strains) of a species. only in taxon only_in_taxon U only_in_taxon T: U is a feature found in only in organisms of species of taxon T. The feature cannot be found in an organism of any species outside of (not subsumed by) that taxon. Down-propagates in U hierarchy, up-propagates in T hierarchy (species taxonomy). Implies applicable_to_taxon. ROC:Waclaw x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. Chris Mungall Jennifer Deegan RO:0002162 uberon in_taxon in_taxon Connects a biological entity to its taxon of origin. in taxon A is spatially_disjoint_from B if and only if they have no parts in common There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. Chris Mungall Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy BFO_0000051 exactly 0 (BFO_0000050 some ?Y) RO:0002163 spatially_disjoint_from spatially disjoint from https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones). a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b RO:0002170 uberon connected_to connected_to connected to connected to https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern The M8 connects Glasgow and Edinburgh a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones). c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system. RO:0002176 uberon connects connects connects connects https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. attached to part of (anatomical structure to anatomical structure) RO:0002177 uberon attaches_to_part_of attached_to_part_of attaches_to_part_of attached to part of attached to part of true Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy. Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure RO:0002178 uberon supplies supplies supplies supplies Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure. Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure RO:0002179 uberon drains drains drains drains w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity. For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit. RO:0002180 external uberon has_component has_component has component has component x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y Chris Mungall David Osumi-Sutherland Melissa Haendel Terry Meehan RO:0002202 uberon develops_from develops_from This is the transitive form of the develops from relation develops from develops from inverse of develops from Chris Mungall David Osumi-Sutherland Terry Meehan RO:0002203 develops_into develops into Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. Chris Mungall David Osumi-Sutherland has developmental precursor FBbt RO:0002207 uberon directly_develops_from directly_develops_from TODO - add child relations from DOS directly develops from directly develops from inverse of directly develops from developmental precursor of RO:0002210 directly_develops_into directly develops into p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q. Chris Mungall David Hill Tanya Berardini GO Regulation precludes parthood; the regulatory process may not be within the regulated process. regulates (processual) false RO:0002211 external gene_ontology regulates regulates regulates regulates p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q. Chris Mungall negatively regulates (process to process) RO:0002212 external gene_ontology negatively_regulates negatively_regulates negatively regulates negatively regulates p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q. Chris Mungall positively regulates (process to process) RO:0002213 external gene_ontology positively_regulates positively_regulates positively regulates positively regulates mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974) osteoclast SubClassOf 'capable of' some 'bone resorption' A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. Chris Mungall has function realized in For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)". RO:0002215 external uberon capable_of capable_of capable of capable of c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. Chris Mungall has function in RO:0002216 external uberon capable_of_part_of capable_of_part_of capable of part of capable of part of true x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x Chris Mungall RO:0002219 uberon surrounded_by surrounded_by surrounded by surrounded by A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts. The epidermis layer of a vertebrate is adjacent to the dermis. The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies. The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used. x adjacent to y if and only if x and y share a boundary. This relation acts as a join point with BSPO Chris Mungall RO:0002220 external spatial uberon adjacent_to adjacent_to adjacent to adjacent to A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts. inverse of surrounded by Chris Mungall RO:0002221 uberon surrounds surrounds surrounds surrounds Chris Mungall Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends. https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1 RO:0002222 temporally_related_to A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations. temporally related to inverse of starts with Chris Mungall Allen RO:0002223 uberon starts starts starts starts Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall started by RO:0002224 external uberon starts_with starts_with starts with starts with x develops from part of y if and only if there exists some z such that x develops from z and z is part of y Chris Mungall RO:0002225 uberon develops_from_part_of develops_from_part_of develops from part of develops from part of x develops_in y if x is located in y whilst x is developing Chris Mungall EHDAA2 Jonathan Bard, EHDAA2 RO:0002226 uberon develops_in develops_in develops in develops in inverse of ends with Chris Mungall RO:0002229 uberon ends ends ends ends x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall finished by RO:0002230 external uberon ends_with ends_with ends with ends with x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y Chris Mungall starts with process that occurs in RO:0002231 external has_start_location has_start_location has start location has start location x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y Chris Mungall ends with process that occurs in RO:0002232 external has_end_location has_end_location has end location has end location p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. Chris Mungall consumes RO:0002233 external has_input has_input has input has input p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. Chris Mungall produces RO:0002234 external has_output has_output has output has output Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong] x has developmental contribution from y iff x has some part z such that z develops from y Chris Mungall RO:0002254 uberon has_developmental_contribution_from has_developmental_contribution_from has developmental contribution from has developmental contribution from inverse of has developmental contribution from Chris Mungall RO:0002255 developmentally_contributes_to developmentally contributes to t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor anatomical structure type T to T', where T' develops_from T t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T Chris Mungall David Osumi-Sutherland Melissa Haendel induced by Developmental Biology, Gilbert, 8th edition, figure 6.5(F) GO:0001759 We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm] RO:0002256 uberon developmentally_induced_by developmentally_induced_by developmentally induced by developmentally induced by Inverse of developmentally induced by Chris Mungall RO:0002257 developmentally_induces developmentally induces Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p false Chris Mungall In general you should not use this relation to make assertions - use one of the more specific relations below this one RO:0002258 developmentally_preceded_by This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from developmentally preceded by A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision. c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. RO:0002263 acts_upstream_of acts upstream of A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway. c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. RO:0002264 affects acts_upstream_of_or_within acts upstream of or within x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage Chris Mungall replaces RO:0002285 uberon developmentally_replaces developmentally_replaces developmentally replaces developmentally replaces Inverse of developmentally preceded by Chris Mungall RO:0002286 developmentally_succeeded_by developmentally succeeded by 'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue Chris Mungall RO:0002287 part_of_developmental_precursor_of part of developmental precursor of p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint. Chris Mungall RO:0002295 external results_in_developmental_progression_of results_in_developmental_progression_of results in developmental progression of results in developmental progression of every flower development (GO:0009908) results in development of some flower (PO:0009046) p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. Chris Mungall http://www.geneontology.org/GO.doc.development.shtml RO:0002296 external results_in_development_of results_in_development_of results in development of results in development of an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists. every "endocardial cushion formation" (GO:0003272) results_in_formation_of some "endocardial cushion" (UBERON:0002062) Chris Mungall GOC:mtg_berkeley_2013 RO:0002297 external results_in_formation_of results_in_formation_of results in formation of results in formation of an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape. tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723) The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. Chris Mungall GOC:mtg_berkeley_2013 RO:0002298 external results_in_morphogenesis_of results_in_morphogenesis_of results in morphogenesis of results in morphogenesis of an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474) The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. Chris Mungall GOC:mtg_berkeley_2013 RO:0002299 external results_in_maturation_of results_in_maturation_of results in maturation of results in maturation of p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q. cjm RO:0002304 external causally_upstream_of,_positive_effect causally_upstream_of,_positive_effect holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y causally upstream of, positive effect p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q. cjm RO:0002305 external causally_upstream_of,_negative_effect causally_upstream_of,_negative_effect causally upstream of, negative effect q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. Because part_of is transitive, inheres in is a sub-relation of characteristic of part of Chris Mungall inheres in part of RO:0002314 characteristic_of_part_of characteristic of part of true an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast. The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity Chris Mungall GOC:mtg_berkeley_2013 RO:0002315 external results_in_acquisition_of_features_of results_in_acquisition_of_features_of results in acquisition of features of results in acquisition of features of A relationship that holds via some environmental process Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution. RO:0002320 evolutionarily_related_to evolutionarily related to A mereological relationship or a topological relationship Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships RO:0002323 mereotopologically_related_to mereotopologically related to A relationship that holds between entities participating in some developmental process (GO:0032502) Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development RO:0002324 developmentally_related_to developmentally related to a particular instances of akt-2 enables some instance of protein kinase activity c enables p iff c is capable of p and c acts to execute p. Chris Mungall catalyzes executes has is catalyzing is executing This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized. RO:0002327 enables enables A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. Chris Mungall This is a grouping relation that collects relations used for the purpose of connecting structure and function RO:0002328 uberon functionally_related_to functionally_related_to functionally related to functionally related to this relation holds between c and p when c is part of some c', and c' is capable of p. Chris Mungall false RO:0002329 part_of_structure_that_is_capable_of part of structure that is capable of true c involved_in p if and only if c enables some process p', and p' is part of p Chris Mungall actively involved in enables part of RO:0002331 involved_in involved in inverse of enables Chris Mungall RO:0002333 enabled_by enabled by inverse of regulates Chris Mungall regulated by (processual) RO:0002334 external regulated_by regulated_by regulated by regulated by inverse of negatively regulates Chris Mungall RO:0002335 external negatively_regulated_by negatively_regulated_by negatively regulated by negatively regulated by inverse of positively regulates Chris Mungall RO:0002336 external positively_regulated_by positively_regulated_by positively regulated by positively regulated by A relationship that holds via some process of localization Chris Mungall Do not use this relation directly. It is a grouping relation. RO:0002337 related_via_localization_to related via localization to This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. Chris Mungall RO:0002338 external has_target_start_location has_target_start_location has target start location has target start location This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. Chris Mungall RO:0002339 external has_target_end_location has_target_end_location has target end location has target end location Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l Chris Mungall RO:0002341 external results_in_transport_along results_in_transport_along results in transport along results in transport along Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. Chris Mungall RO:0002342 external results_in_transport_across results_in_transport_across results in transport across results in transport across 'pollen tube growth' results_in growth_of some 'pollen tube' Chris Mungall RO:0002343 external results_in_growth_of results_in_growth_of results in growth of results in growth of 'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739) Chris Mungall RO:0002344 external results_in_transport_to_from_or_in results_in_transport_to_from_or_in results in transport to from or in results in transport to from or in An organism that is a member of a population of organisms is member of is a mereological relation between a item and a collection. is member of member part of SIO RO:0002350 member_of member of has member is a mereological relation between a collection and an item. SIO RO:0002351 uberon has_member has_member has member has member inverse of has input Chris Mungall RO:0002352 uberon input_of input_of input of input of inverse of has output Chris Mungall RO:0002353 external protein uberon output_of false output_of output of output of output_of Chris Mungall RO:0002354 formed_as_result_of formed as result of a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a Chris Mungall attached to (anatomical structure to anatomical structure) RO:0002371 uberon attaches_to attached_to attaches_to attached to attached to m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. Chris Mungall Wikipedia:Insertion_(anatomy) RO:0002372 uberon has_muscle_origin has_muscle_origin has muscle origin has muscle origin We need to import uberon muscle to create a stricter domain constraint m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. Chris Mungall Wikipedia:Insertion_(anatomy) RO:0002373 uberon has_muscle_insertion has_muscle_insertion has muscle insertion has muscle insertion We need to import uberon muscle into RO to use as a stricter domain constraint A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network. Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves) RO:0002375 in_branching_relationship_with in branching relationship with https://github.com/obophenotype/uberon/issues/170 Deschutes River tributary_of Columbia River inferior epigastric vein tributary_of external iliac vein x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein. Chris Mungall drains into drains to tributary channel of http://en.wikipedia.org/wiki/Tributary http://www.medindia.net/glossary/venous_tributary.htm This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries) RO:0002376 uberon tributary_of tributary_of tributary of tributary of http://en.wikipedia.org/wiki/Tributary A lump of clay and a statue x spatially_coextensive_with y if and inly if x and y have the same location Chris Mungall This relation is added for formal completeness. It is unlikely to be used in many practical scenarios RO:0002379 spatially_coextensive_with spatially coextensive with In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y Chris Mungall RO:0002380 uberon branching_part_of branching_part_of branching part of branching part of FMA:85994 x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). Chris Mungall RO:0002384 has_developmental_potential_involving has developmental potential involving x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y Chris Mungall RO:0002385 uberon has_potential_to_developmentally_contribute_to has_potential_to_developmentally_contribute_to has potential to developmentally contribute to has potential to developmentally contribute to x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y Chris Mungall RO:0002386 has_potential_to_developmentally_induce has potential to developmentally induce x has the potential to develop into y iff x develops into y or if x is capable of developing into y Chris Mungall RO:0002387 uberon has_potential_to_develop_into has_potential_to_develop_into has potential to develop into has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y Chris Mungall RO:0002388 has_potential_to_directly_develop_into has potential to directly develop into inverse of upstream of Chris Mungall RO:0002404 external causally_downstream_of causally_downstream_of causally downstream of causally downstream of Chris Mungall RO:0002405 external immediately_causally_downstream_of immediately_causally_downstream_of immediately causally downstream of immediately causally downstream of p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q. Chris Mungall indirectly activates RO:0002407 indirectly_positively_regulates indirectly positively regulates p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q. Chris Mungall indirectly inhibits RO:0002409 indirectly_negatively_regulates indirectly negatively regulates relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yield a cross-product of different relation types. Chris Mungall Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. RO:0002410 causally_related_to causally related to relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. https://en.wikipedia.org/wiki/Causality p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. Chris Mungall RO:0002411 external causally_upstream_of causally_upstream_of causally upstream of causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. Chris Mungall RO:0002412 external immediately_causally_upstream_of immediately_causally_upstream_of immediately causally upstream of immediately causally upstream of p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q. We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2 Chris Mungall influences (processual) RO:0002418 external affects causally_upstream_of_or_within causally_upstream_of_or_within causally upstream of or within inverse of causally upstream of or within Chris Mungall RO:0002427 external causally_downstream_of_or_within causally_downstream_of_or_within causally downstream of or within c involved in regulation of p if c is involved in some p' and p' regulates some p Chris Mungall RO:0002428 involved_in_regulation_of involved in regulation of c involved in regulation of p if c is involved in some p' and p' positively regulates some p Chris Mungall RO:0002429 involved_in_positive_regulation_of involved in positive regulation of c involved in regulation of p if c is involved in some p' and p' negatively regulates some p Chris Mungall RO:0002430 involved_in_negative_regulation_of involved in negative regulation of c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p OWL does not allow defining object properties via a Union Chris Mungall involved in or reguates RO:0002431 involved_in_or_involved_in_regulation_of involved in or involved in regulation of A protein that enables activity in a cytosol. c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. Chris Mungall executes activity in RO:0002432 enables activity in is_active_in is active in true c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. GOC:cjm GOC:dos p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm. Chris Mungall RO:0002433 uberon contributes_to_morphology_of contributes_to_morphology_of contributes to morphology of A relationship that holds between two entities in which the processes executed by the two entities are causally connected. Considering relabeling as 'pairwise interacts with' This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact. Chris Mungall Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules. RO:0002434 in pairwise interaction with interacts_with interacts with http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ http://purl.obolibrary.org/obo/MI_0914 An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. Chris Mungall binds molecularly binds with RO:0002436 molecularly_interacts_with molecularly interacts with http://purl.obolibrary.org/obo/MI_0915 Axiomatization to GO to be added later Chris Mungall An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y. RO:0002447 phosphorylates phosphorylates The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. Chris Mungall Vasundra Touré RO:0002448 molecularly controls directly_regulates_activity_of directly regulates activity of The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. Chris Mungall Vasundra Touré directly inhibits RO:0002449 molecularly decreases activity of directly_negatively_regulates_activity_of directly negatively regulates activity of The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. Chris Mungall Vasundra Touré directly activates RO:0002450 molecularly increases activity of directly_positively_regulates_activity_of directly positively regulates activity of Chris Mungall This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning. RO:0002464 helper_property_(not_for_use_in_curation) helper property (not for use in curation) 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate' x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. Chris Mungall RO:0002473 uberon composed_primarily_of composed_primarily_of composed primarily of p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. Chris Mungall RO:0002479 has_part_that_occurs_in has part that occurs in true Chris Mungall RO:0002481 is_kinase_activity is kinase activity Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage. RO:0002487 relation_between_physical_entity_and_a_process_or_stage relation between physical entity and a process or stage x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). Chris Mungall RO:0002488 uberon existence_starts_during existence_starts_during existence starts during x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). Chris Mungall RO:0002489 uberon existence_starts_with existence_starts_with existence starts with x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) Chris Mungall RO:0002490 existence_overlaps The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence overlaps x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y) Chris Mungall RO:0002491 exists during uberon existence_starts_and_ends_during existence_starts_and_ends_during The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence starts and ends during Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). Chris Mungall RO:0002492 ceases_to_exist_during uberon existence_ends_during existence_ends_during The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends during Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. https://orcid.org/0000-0002-6601-2165 x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). Chris Mungall RO:0002493 uberon existence_ends_with existence_ends_with The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends with x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships Chris Mungall RO:0002494 uberon transformation_of transformation_of transformation of x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t Chris Mungall RO:0002495 uberon immediate_transformation_of immediate_transformation_of immediate transformation of x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). Chris Mungall RO:0002496 uberon existence_starts_during_or_after existence_starts_during_or_after The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence starts during or after x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. Chris Mungall RO:0002497 uberon existence_ends_during_or_before existence_ends_during_or_before The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends during or before A relationship between a material entity and a process where the material entity has some causal role that influences the process RO:0002500 causal_agent_in_process causal agent in process p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q. Chris Mungall Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. RO:0002501 causal_relation_between_processes causal relation between processes Chris Mungall RO:0002502 depends_on depends on The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch Chris Mungall Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. RO:0002506 causal_relation_between_entities causal relation between entities Forelimb SubClassOf has_skeleton some 'Forelimb skeleton' A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision. Chris Mungall has supporting framework The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell). RO:0002551 uberon has_skeleton has_skeleton has skeleton This should be to a more restricted class, but not the Uberon class may be too restricted since it is a composition-based definition of skeleton rather than functional. Chris Mungall causally influenced by (entity-centric) RO:0002559 causally_influenced_by causally influenced by Chris Mungall RO:0002563 interaction_relation_helper_property interaction relation helper property http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ Chris Mungall RO:0002564 molecular_interaction_relation_helper_property molecular interaction relation helper property The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). Chris Mungall Vasundra Touré causally influences (entity-centric) RO:0002566 causally_influences causally influences A relation that holds between elements of a musculoskeletal system or its analogs. Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes. RO:0002567 biomechanically_related_to biomechanically related to m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. Chris Mungall Wikipedia:Antagonist_(muscle) RO:0002568 uberon has_muscle_antagonist has_muscle_antagonist has muscle antagonist inverse of branching part of Chris Mungall RO:0002569 uberon has_branching_part has_branching_part has branching part x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull. Chris Mungall GOC:cjm RO:0002571 uberon lumen_of lumen_of lumen of s is luminal space of x iff s is lumen_of x and s is an immaterial entity Chris Mungall RO:0002572 uberon luminal_space_of luminal_space_of luminal space of inverse of has skeleton Chris Mungall RO:0002576 uberon skeleton_of skeleton_of skeleton of p directly regulates q iff p is immediately causally upstream of q and p regulates q. Chris Mungall directly regulates (processual) RO:0002578 external directly_regulates directly_regulates directly regulates gland SubClassOf 'has part structure that is capable of' some 'secretion by cell' s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p Chris Mungall RO:0002584 has_part_structure_that_is_capable_of has part structure that is capable of p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p RO:0002586 results_in_breakdown_of results in breakdown of RO:0002588 external results_in_assembly_of results_in_assembly_of results in assembly of RO:0002590 external results_in_disassembly_of results_in_disassembly_of results in disassembly of p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c RO:0002592 external results_in_organization_of results_in_organization_of results in organization of A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. Chris Mungall RO:0002595 causal_relation_between_material_entity_and_a_process causal relation between material entity and a process pyrethroid -> growth Holds between c and p if and only if c is capable of some activity a, and a regulates p. RO:0002596 capable_of_regulating capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. RO:0002597 capable_of_negatively_regulating capable of negatively regulating renin -> arteriolar smooth muscle contraction Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. RO:0002598 capable_of_positively_regulating capable of positively regulating Inverse of 'causal agent in process' RO:0002608 external process_has_causal_agent process_has_causal_agent process has causal agent p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q. directly positively regulates (process to process) RO:0002629 external directly_positively_regulates directly_positively_regulates directly positively regulates p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q. directly negatively regulates (process to process) RO:0002630 external directly_negatively_regulates directly_negatively_regulates directly negatively regulates a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. Melissa Haendel RO:0003000 external uberon produces produces Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue. produces produces a produced_by b iff some process that occurs_in b has_output a. Melissa Haendel RO:0003001 external uberon produced_by produced_by produced by produced by p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. cjm 2018-12-13T11:26:17Z RO:0004007 external has_primary_input_or_output has_primary_input_or_output has primary input or output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. cjm 2018-12-13T11:26:32Z RO:0004008 external has_primary_output has_primary_output has primary output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. GOC:cjm GOC:dph GOC:kva GOC:pt PMID:27812932 p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. cjm 2018-12-13T11:26:56Z RO:0004009 external has_primary_input has_primary_input has primary input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. GOC:cjm GOC:dph GOC:kva GOC:pt PMID:27812932 Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. cjm 2018-01-25T23:20:13Z RO:0004031 enables_subfunction enables subfunction cjm 2018-01-26T23:49:30Z RO:0004032 acts_upstream_of_or_within,_positive_effect acts upstream of or within, positive effect cjm 2018-01-26T23:49:51Z RO:0004033 acts_upstream_of_or_within,_negative_effect acts upstream of or within, negative effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive cjm 2018-01-26T23:53:14Z RO:0004034 acts_upstream_of,_positive_effect acts upstream of, positive effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative cjm 2018-01-26T23:53:22Z RO:0004035 acts_upstream_of,_negative_effect acts upstream of, negative effect cjm 2018-03-13T23:55:05Z RO:0004046 causally_upstream_of_or_within,_negative_effect causally upstream of or within, negative effect cjm 2018-03-13T23:55:19Z RO:0004047 causally_upstream_of_or_within,_positive_effect causally upstream of or within, positive effect The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. Vasundra Touré RO:0011002 regulates_activity_of regulates activity of p acts on population of c iff c' is a collection, has members of type c, and p has participant c pg 2020-06-08T17:21:33Z RO:0012003 external acts_on_population_of acts_on_population_of acts on population of acts on population of pg 2021-02-26T07:28:29Z RO:0012008 external results_in_fusion_of results_in_fusion_of results in fusion of results in fusion of p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q. pg 2022-09-26T06:07:17Z RO:0012011 indirectly_causally_upstream_of indirectly causally upstream of p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q. pg 2022-09-26T06:08:01Z RO:0012012 indirectly_regulates indirectly regulates q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015006 different_in_magnitude_relative_to different in magnitude relative to q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015007 increased_in_magnitude_relative_to This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'. increased in magnitude relative to q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'. decreased in magnitude relative to q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. RO:0015011 has_cross_section Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round. has cross section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. https://orcid.org/0000-0002-6601-2165 q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e. There are frequently two ways to state the same thing: we can say 'spermatocyte lacks asters' or 'asters absent from spermatocyte'. In this case the quality is 'lacking all parts of type' - it is a (relational) quality of the spermatocyte, and it is with respect to instances of 'aster'. One of the popular requirements of PATO is that it continue to support 'absent', so we need to relate statements which use this quality to the 'lacking all parts of type' quality. reciprocal of q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e. https://orcid.org/0000-0002-6601-2165 A diagnostic testing device utilizes a specimen. X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y. https://orcid.org/0000-0001-9625-1899 https://orcid.org/0000-0003-2620-0345 A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input. See github ticket https://github.com/oborel/obo-relations/issues/497 2021-11-08T12:00:00Z utilizes RO:0017001 device_utilizes_material device utilizes material A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C. RO:0019000 gene_ontology regulates_characteristic regulates_characteristic regulates characteristic A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C. RO:0019001 gene_ontology positively_regulates_characteristic positively_regulates_characteristic positively regulates characteristic A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C. RO:0019002 gene_ontology negatively_regulates_characteristic negatively_regulates_characteristic negatively regulates characteristic p has anatomical participant c iff p has participant c, and c is an anatomical entity cjm 2018-09-26T01:08:58Z RO:0040036 external results_in_changes_to_anatomical_or_cellular_structure results_in_changes_to_anatomical_or_cellular_structure results in changes to anatomical or cellular structure http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y lacks_part http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y) lacks_plasma_membrane_part OBSOLETE. q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015008 quality decreased_in_magnitude_relative_to Refer to https://github.com/pato-ontology/pato/issues/454 for obsoletion reason. This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'. obsolete decreased_in_magnitude_relative_to true OBSOLETE. q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. PATOC:CJM OBSOLETE. q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015006 quality different_in_magnitude_relative_to Refer to https://github.com/pato-ontology/pato/issues/454 for obsoletion reason. obsolete different_in_magnitude_relative_to true OBSOLETE. q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. PATOC:CJM OBSOLETE. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015007 quality increased_in_magnitude_relative_to Refer to https://github.com/pato-ontology/pato/issues/454. This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'. obsolete increased_in_magnitude_relative_to true OBSOLETE. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. PATOC:CJM OBSOLETE. q1 similar_in_magnitude_relative_to q2 if and only if magnitude(q1) =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015009 quality similar_in_magnitude_relative_to Refer to https://github.com/pato-ontology/pato/issues/454 for obsoletion reason. obsolete similar_in_magnitude_relative_to true OBSOLETE. q1 similar_in_magnitude_relative_to q2 if and only if magnitude(q1) =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. PATOC:CJM protein has_gene_template false has_gene_template x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. uberon anteriorly_connected_to anteriorly connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern carries uberon channel_for channel for uberon channels_from channels_from uberon channels_into channels_into x is a conduit for y iff y passes through the lumen of x. uberon conduit_for conduit for x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. uberon distally_connected_to distally connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y uberon extends_fibers_into extends_fibers_into X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y https://orcid.org/0000-0002-7073-9172 Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. uberon filtered_through Relationship between a fluid and a filtration barrier, where the portion of fluid arises as a transformation of another portion of fluid on the other side of the barrier, with larger particles removed filtered through a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s. add to RO uberon indirectly_supplies indirectly_supplies uberon layer_part_of layer part of x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. uberon posteriorly_connected_to posteriorly connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern uberon protects protects x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. uberon proximally_connected_to proximally connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern c site_of p if c is the bearer of a disposition that is realized by a process that has p as part. uberon capable_of_has_part site_of site_of uberon subdivision_of placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B subdivision of Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. uberon synapsed_by synapsed by . uberon transitively_anteriorly_connected_to transitively anteriorly connected to . http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern uberon transitively_connected_to transitively_connected to . uberon transitively_distally_connected_to transitively distally connected to . http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern . uberon transitively_proximally_connected_to transitively proximally connected to . http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern A protein coding gene resilin in fruit fly. gene FlyBase:FBgn0034157 Category=external. resilin (fruit fly) A protein coding gene resilin in fruit fly. PRO:DNx The projection of the inner surface of the cuticle. cuticular internal depression imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The projection of the inner surface of the cuticle. jgiron https://orcid.org/0000-0002-0851-6883 2021-05-19 The region of cuticle that is composed two articular surfaces that are adjacent to each other. Articulations are 'anatomical clusters', collections of not direclty connected (continuous) sclerite surfaces that are adjacent to another sclerite. The cranio-mandibular articulation is the articular surface of the cranium and the adjacent articular surface of the mandible. The articular surfaces are sometimes located on the same sclerite. insect articulation imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of cuticle that is composed two articular surfaces that are adjacent to each other. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 Articulations are 'anatomical clusters', collections of not direclty connected (continuous) sclerite surfaces that are adjacent to another sclerite. The cranio-mandibular articulation is the articular surface of the cranium and the adjacent articular surface of the mandible. The articular surfaces are sometimes located on the same sclerite. imiko https://orcid.org/0000-0003-2938-9075 The region of the insect cuticle that is less flexible than the neighboring conjunctiva(e) (conjunctiva(e) that the sclerite is continuous with. http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00004475 http://purl.obolibrary.org/obo/HAO_0000909 http://purl.obolibrary.org/obo/UBERON_6004475 esclerito insect sclerite imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of the insect cuticle that is less flexible than the neighboring conjunctiva(e) (conjunctiva(e) that the sclerite is continuous with. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00004475 sclerite http://purl.obolibrary.org/obo/HAO_0000909 The area of the cuticle that is less flexible than adjacent conjunctivae. sclerite http://purl.obolibrary.org/obo/UBERON_6004475 insect sclerite esclerito jgiron https://orcid.org/0000-0002-0851-6883 2023-01-09 insect sclerite Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Sclerite: distinctly sclerotized region of the integument, with thick layer of exocuticle." Modified 2023-01-09: specifying insect sclerite. jgiron https://orcid.org/0000-0002-0851-6883 The region of the insect cuticle that is more flexible than the neighboring sclerite(s) [sclerite(s) that the conjunctiva is continuous with]. Conjunctivae are more flexible and usually less thick than sclerties of the cuticle allowing the sclerites to move relative to each other. Micro-CT based methods cannot be used to accurately differentiate slcerites from conjunctiuvae. CLSM (the excitation wavelengths of sclerites and conjunctivae are different in response of 488 nm emission vawelength), histological sections or simple dissections need to be applied to define relative flexibility of the insect cuticle. If a conjunctiva entirelly encircles a sclerite, then the 'encircles' and 'encircled by' object properties are used to link the sclerite and the conjunctiva even in cases in which the encircled sclerites or conjunctivae are part of an evagination allowing to model spatial relationship between appendage segments: the pedicel is encircled by the scapal-pedicellar conjunctiva, which is encircled by the scape or the the coxa encircles the coxo-femoral conjunctiuva that encircels the femur. http://purl.obolibrary.org/obo/HAO_0000221 membrane conjunctiva imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of the insect cuticle that is more flexible than the neighboring sclerite(s) [sclerite(s) that the conjunctiva is continuous with]. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 Conjunctivae are more flexible and usually less thick than sclerties of the cuticle allowing the sclerites to move relative to each other. Micro-CT based methods cannot be used to accurately differentiate slcerites from conjunctiuvae. CLSM (the excitation wavelengths of sclerites and conjunctivae are different in response of 488 nm emission vawelength), histological sections or simple dissections need to be applied to define relative flexibility of the insect cuticle. If a conjunctiva entirelly encircles a sclerite, then the 'encircles' and 'encircled by' object properties are used to link the sclerite and the conjunctiva even in cases in which the encircled sclerites or conjunctivae are part of an evagination allowing to model spatial relationship between appendage segments: the pedicel is encircled by the scapal-pedicellar conjunctiva, which is encircled by the scape or the the coxa encircles the coxo-femoral conjunctiuva that encircels the femur. imiko https://orcid.org/0000-0003-2938-9075 http://purl.obolibrary.org/obo/HAO_0000221 The area of the cuticle that is more flexible than adjacent sclerites. conjunctiva membrane Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Membrane: very flexible, unsclerotized area of the integument." The region of the cuticle that corresponds to a concave surface. External cuticular depression. The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Concavities sometimes correspons with invaginations of the cuticle and the underlaying sinlge layer epidermis, somtimes correspond to a decreased cuticular thickness. cuticular depression imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of the cuticle that corresponds to a concave surface. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 External cuticular depression. The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Concavities sometimes correspons with invaginations of the cuticle and the underlaying sinlge layer epidermis, somtimes correspond to a decreased cuticular thickness. imiko https://orcid.org/0000-0003-2938-9075 The region of cuticle that corresponds with an invagination of the single layer epidermis (epidermal fold). The cuticular invagination sometimes corresponds to a cuticular depression (concavity on the surface of the cuticle). cuticular invagination imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of cuticle that corresponds with an invagination of the single layer epidermis (epidermal fold). The cuticular invagination sometimes corresponds to a cuticular depression (concavity on the surface of the cuticle). imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 The region of cuticle with higher content of resilin. elastic cuticle imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of cuticle with higher content of resilin. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 elastic cuticle 2020-10-27 The region of the cuticle that corresponds to a convex surface. The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Convexities sometimes correspons with evaginations of the cuticle and the underlaying sinlge layer epidermis and sometimes correspond to an increased cuticular thickness." cuticular protrusion imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of the cuticle that corresponds to a convex surface. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Convexities sometimes correspons with evaginations of the cuticle and the underlaying sinlge layer epidermis and sometimes correspond to an increased cuticular thickness." imiko https://orcid.org/0000-0003-2938-9075 A part or structure that is produced by evagination. evaginated imiko https://orcid.org/0000-0003-2938-9075 A part or structure that is produced by evagination. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 evaginated imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 The articulation between the mandible and the cranium. cranio-mandibular articulation imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The articulation between the mandible and the cranium. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 The articulation between the cardo and the cranium. cranio-cardinal articulation imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The articulation between the cardo and the cranium. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 The articulation between the scapus and the cranium. cranio-antennal articulation imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The articulation between the scapus and the cranium. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 The articulation between the head and the neck. head-cervical articulation imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The articulation between the head and the neck. imiko https://orcid.org/0000-0003-2938-9075 2020-10-27 The sclerite of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and to the cuticle of stipes by the stipito-cardinal conjunctiva. cuticle of cardo imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 The sclerite of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and to the cuticle of stipes by the stipito-cardinal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-02-19 cuticle of cardo Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Cardo: basal element of maxilla, articulating with head capsule; usually moved by one cranial muscle and one tentorial muscle." The sclerite of the insect head that is attached to the neck membrane and the oral foraminal conjunctiva, bears the eye cuticle and surrounds the brain cephalic capsule insect cranium head capsule imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The sclerite of the insect head that is attached to the neck membrane and the oral foraminal conjunctiva, bears the eye cuticle and surrounds the brain jgiron https://orcid.org/0000-0002-0851-6883 2021-02-19 cephalic capsule jgiron https://orcid.org/0000-0002-0851-6883 insect cranium imiko https://orcid.org/0000-0003-2938-9075 head capsule Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "The head capsule is almost always a rigid, well sclerotized structural unit, equipped with a defined set of appendages. It is reinforced by strengthening ridges and the endoskeletal tentorium" The axillary sclerite that is on the dorsal region of the basal wing conjunctiva and lateral to the first axillary sclerite. dorsal second axillary sclerite imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 The axillary sclerite that is on the dorsal region of the basal wing conjunctiva and lateral to the first axillary sclerite. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-10 Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the tergum by the metanoto-abdominal tergite I conjunctiva and to the anterior margin of the abdominal tergite II by the abdominal tergite I-abdominal tergite II conjunctiva. abdominal tergite I jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the tergum by the metanoto-abdominal tergite I conjunctiva and to the anterior margin of the abdominal tergite II by the abdominal tergite I-abdominal tergite II conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-03-18 The axillary sclerite that is part of the dorsal region of the basal wing conjunctiva and is anterior to the third axillary sclerite. first axillary sclerite imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The axillary sclerite that is part of the dorsal region of the basal wing conjunctiva and is anterior to the third axillary sclerite. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-10 The cuticle of the appendage of the insect maxilla that is attached to the stipes by the stipito-galeal conjunctiva. cuticle of galea jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the appendage of the insect maxilla that is attached to the stipes by the stipito-galeal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of galea Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Galea: outer endite lobe of maxilla, usually semimembranous and equipped with sensilla (mainly chemoreceptors)." 2021-12-08 The cuticle of the paired appendage of the labium that is attached to the palpiger by the palpigero-palpal conjunctiva. cuticle of labial palpus imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the paired appendage of the labium that is attached to the palpiger by the palpigero-palpal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of labial palpus Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Labial palp: tactile appendage of the labium." 2021-12-08 The cuticle of the appendage of the insect maxilla that is attached to the cuticle of stipes by the stipito-lacinial conjunctiva. cuticle of lacinia jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the appendage of the insect maxilla that is attached to the cuticle of stipes by the stipito-lacinial conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of lacinia Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Lacinia: inner endite lobe of maxilla, usually firmly connected or fused with stipes; usually sclerotized, with mesally curved apex and articulated spines arranged along mesal edge." 2021-12-08 The region of cuticle that corresponds with an evagination of the cuticle and the single layer epidermis (epidermal fold). The cuticular evagination usually corresponds to a cuticular protrusion (convexity on the surface of the cuticle). cuticular evagination jgiron https://orcid.org/0000-0002-0851-6883 2021-08-01 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The region of cuticle that corresponds with an evagination of the cuticle and the single layer epidermis (epidermal fold). The cuticular evagination usually corresponds to a cuticular protrusion (convexity on the surface of the cuticle). imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 The cuticular protrusion that does not correspond to an evagination. solid cuticular protrusion imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The cuticular protrusion that does not correspond to an evagination. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 solid cuticular protrusion 2020-11-11 The evagination of the cuticle that is musculated (connected to the body via muscles). cuticle of insect appendage jgiron https://orcid.org/0000-0002-0851-6883 2021-08-01 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The evagination of the cuticle that is musculated (connected to the body via muscles). imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 cuticle of insect appendage Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp. https://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf "any part, piece, or organ attached by a joint to the body or to any other main structure" 2021-12-08 The cuticle of the paired appendage of the insect thorax that is composed of coxa, trochanter, femur, tibia, tarsus, and pretarsus. cuticle of insect leg jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the paired appendage of the insect thorax that is composed of coxa, trochanter, femur, tibia, tarsus, and pretarsus. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of insect leg 2021-12-08 The cuticle of the appendage of the head capsule that is connected by the antenniferal-scapal conjunctiva to the cuticle of the scapus, which is connected by the scapal-pedicellar conjunctiva to the cuticle of the pedicellus; the cuticle of the pedicellus is connected by the pedicellar-first flagellomeral conjunctiva to the cuticle of the first flagellomere; the cuticle of the first flagellomere is connected by interflagellomeral conjunctiva to the next cuticle of flagellomere. Further cuticle of flagellomeres are connected to each other by interflagellomeral conjunctiva. cuticle of antenna imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the appendage of the head capsule that is connected by the antenniferal-scapal conjunctiva to the cuticle of the scapus, which is connected by the scapal-pedicellar conjunctiva to the cuticle of the pedicellus; the cuticle of the pedicellus is connected by the pedicellar-first flagellomeral conjunctiva to the cuticle of the first flagellomere; the cuticle of the first flagellomere is connected by interflagellomeral conjunctiva to the next cuticle of flagellomere. Further cuticle of flagellomeres are connected to each other by interflagellomeral conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of antenna Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Antenna: head appendage of segment 2, innervated by deutocerebrum; in Insecta composed of scapus, pedicellus and flagellum; primarily multisegmented and filiform." 2021-12-08 The cuticle of the flat, paired appendage on the dorso-lateral region of the pterothorax. cuticle of insect wing imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the flat, paired appendage on the dorso-lateral region of the pterothorax. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-21 cuticle of insect wing Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp. https://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf "in adult insects or subimago of Ephemeroptera, paired mambranous appendages, supported by veins, located on the mesothorax or metathorax, functioning in flight" 2021-12-08 The cuticle of the paired appendage of the prothorax that is anterior to the cuticle of a mid leg and composed of cuticle of procoxa, cuticle of protrochanter, cuticle of profemur, cuticle of protibia, cuticle of protarsus, and cuticle of propretarsus. cuticle of fore leg jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the paired appendage of the prothorax that is anterior to the cuticle of a mid leg and composed of cuticle of procoxa, cuticle of protrochanter, cuticle of profemur, cuticle of protibia, cuticle of protarsus, and cuticle of propretarsus. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-03 cuticle of fore leg 2021-12-08 The cuticle of the paired appendage of the mesothorax that is posterior to the cuticle of a fore leg, anterior to the cuticle of a hind leg, and composed of cuticle of mesocoxa, cuticle of mesotrochanter, cuticle of mesofemur, cuticle of mesotibia, cuticle of mesotarsus, and cuticle of mesopretarsus. cuticle of mid leg jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the paired appendage of the mesothorax that is posterior to the cuticle of a fore leg, anterior to the cuticle of a hind leg, and composed of cuticle of mesocoxa, cuticle of mesotrochanter, cuticle of mesofemur, cuticle of mesotibia, cuticle of mesotarsus, and cuticle of mesopretarsus. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-03 cuticle of mid leg 2021-12-08 The cuticle of the paired appendage of the metathorax that is posterior to the cuticle of a mid leg and composed of cuticle of metacoxa, cuticle of metatrochanter, cuticle of metafemur, cuticle of metatibia, cuticle of metatarsus, and cuticle of metapretarsus. cuticle of hind leg jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the paired appendage of the metathorax that is posterior to the cuticle of a mid leg and composed of cuticle of metacoxa, cuticle of metatrochanter, cuticle of metafemur, cuticle of metatibia, cuticle of metatarsus, and cuticle of metapretarsus. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-03 cuticle of hind leg 2021-12-08 The cuticle of the paired insect wing that is continuous with the mesonotum. cuticle of fore wing imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The cuticle of the paired insect wing that is continuous with the mesonotum. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-21 cuticle of fore wing 2021-12-08 The cuticle of the paired insect wing that is continuous with the metanotum. cuticle of hind wing imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The cuticle of the paired insect wing that is continuous with the metanotum. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-21 cuticle of hind wing 2021-12-08 The unicellular cuticular evagination that constitutes a sclerite with its base surrounded by socket membrane. cuticular seta imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The unicellular cuticular evagination that constitutes a sclerite with its base surrounded by socket membrane. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 cuticular seta Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Seta (=macrotrichium): articulated hair with socket, formed by trichogen cell." 2021-12-10 2020-11-11 The multicellular evagination of the cuticle that corresponds to an epithelial fold, composed of some sclerite that is encricled by a conjunctiva (moveable). The difference between an appendage and a spur is the lack of muscles attached to the spur, otherwise, the mandible would be also a spur. Spines are multicellular evaginations that are not encircled by conjunctivae. Moveable beetle horns are spurs while not moveable beetle horns are spines. cuticular spur imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The multicellular evagination of the cuticle that corresponds to an epithelial fold, composed of some sclerite that is encricled by a conjunctiva (moveable). imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 The difference between an appendage and a spur is the lack of muscles attached to the spur, otherwise, the mandible would be also a spur. Spines are multicellular evaginations that are not encircled by conjunctivae. Moveable beetle horns are spurs while not moveable beetle horns are spines. imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 cuticular spur Richards AG, Richards PA (1979) The cuticular protuberances of insects. International Journal of Insect Morphology and Embryology 8: 143–157. "Multicellular protuberances without differentiation of specialized cells" 2021-12-10 https://doi.org/10.1016/0020-7322(79)90013-8 The seta that is flat. cuticular scale imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The seta that is flat. imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 cuticular scale 2021-12-10 The cuticle of the mouthpart and appendage that is attached to the clypeus by the clypeo-labral conjunctiva and to the proximal margin of the epipharynx. cuticle of labrum imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the mouthpart and appendage that is attached to the clypeus by the clypeo-labral conjunctiva and to the proximal margin of the epipharynx. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of labrum Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Labrum: unpaired upper lip, connected with distal edge of clypeus." 2021-12-08 The cuticle of the mouthpart and sclerite between the cuticle of the labrum and the cuticle of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and the cranio-mandibular muscle. cuticle of insect mandible imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the mouthpart and sclerite between the cuticle of the labrum and the cuticle of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and the cranio-mandibular muscle. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of insect mandible Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "The mandibles are the paired appendages of the 4th head segment and receive their innervation from the anterior part of the suboesophageal ganglion [...] They are primarily a compact, undivided and strongly sclerotized element without appendages." 2021-12-08 The cuticle of the mouthpart appendage of the head capsule, between the cuticle of the insect mandible and the cuticle of the labium, composed of cuticle of cardo, which is attached to the cuticle of stipes by the cardo-stipital conjunctiva; the cuticle of stipes, which is attached to the cuticle of galea by the stipito-galeal conjunctiva, to the cuticle of lacinia by the stipito-lacinial conjunctiva, and to the cuticle of palpifer by the stipito-palpiferal conjunctiva; the cuticle of palpifer is attached to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva. cuticle of insect maxilla imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the mouthpart appendage of the head capsule, between the cuticle of the insect mandible and the cuticle of the labium, composed of cuticle of cardo, which is attached to the cuticle of stipes by the cardo-stipital conjunctiva; the cuticle of stipes, which is attached to the cuticle of galea by the stipito-galeal conjunctiva, to the cuticle of lacinia by the stipito-lacinial conjunctiva, and to the cuticle of palpifer by the stipito-palpiferal conjunctiva; the cuticle of palpifer is attached to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of insect maxilla Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Maxilla: head appendage of segment 5, innervated by maxillary nerve originating from intermediate part of suboesophageal complex; primarily composed of cardo, stipes, endite lobes (lacinia, galea) and maxillary palp." 2021-12-08 The conjunctiva of the insect thorax that connects the mesothorax and the metathorax. mesothoracic-metathoracic conjunctiva imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The conjunctiva of the insect thorax that connects the mesothorax and the metathorax. jgiron https://orcid.org/0000-0002-0851-6883 2021-03-18 The conjunctiva of the insect thorax joining the prothorax and the mesothorax. prothoracic-mesothoracic conjunctiva jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The conjunctiva of the insect thorax joining the prothorax and the mesothorax. jgiron https://orcid.org/0000-0002-0851-6883 2020-03-18 The cuticle of the appendage of the insect leg that is attached to the cuticle of tarsus by the tarso-pretarsal conjunctiva. ungues cuticle of pretarsus jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the appendage of the insect leg that is attached to the cuticle of tarsus by the tarso-pretarsal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 ungues Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Ungues: pretarsal claws; unpaired in Collembola and Protura, usually paired in Diplura and Insecta." cuticle of pretarsus 2021-12-08 The cuticle of the appendage of the cuticle of labium composed of the cuticle of glossa and cuticle of paraglossa jointly. cuticle of ligula imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the appendage of the cuticle of labium composed of the cuticle of glossa and cuticle of paraglossa jointly. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of ligula Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp. https://www.jstor.org/stable/10.7591/j.ctv1nhm1j "Ligula - The terminal lobes of the labium collectively, or a terminal part of the labium formed by the union of the lobes." 2021-12-08 The cuticle of the appendage of the labium, and part of the ligula, that is attached to the prementum by the premental-glossal conjunctiva. cuticle of glossa imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the appendage of the labium, and part of the ligula, that is attached to the prementum by the premental-glossal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of glossa Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Glossa: paired inner endite lobes of the prementum." 2021-12-08 The cuticle of the paired appendage of the labium, and part of the ligula, that is attached to the cuticle of prementum by the premental-paraglossal conjunctiva. cuticle of paraglossa imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the paired appendage of the labium, and part of the ligula, that is attached to the cuticle of prementum by the premental-paraglossal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of paraglossa Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Paraglossa: paired outer endite lobes of the prementum (labium)." 2021-12-08 The cuticle of the appendage of the insect maxilla that is attached to the cuticle of palpifer by the palpifero-palpal conjunctiva. cuticle of maxillary palpus imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the appendage of the insect maxilla that is attached to the cuticle of palpifer by the palpifero-palpal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of maxillary palpus Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Palp: tactile appendage of maxilla" 2021-12-08 The notum or sclerite on the dorsal region of the mesothorax that is posterior to the pronotum, connected via the mesonoto-mesopleural conjuntiva to the dorsal margin of the mesopleuron, that is not adjacent to the mesocoxa, but attached to it by the mesocoxal muscle. mesonotum jcgiron imiko https://orcid.org/0000-0003-2938-9075 jcgiron jgiron https://orcid.org/0000-0002-0851-6883 jcgiron jcgiron jcgiron jcgiron The notum or sclerite on the dorsal region of the mesothorax that is posterior to the pronotum, connected via the mesonoto-mesopleural conjuntiva to the dorsal margin of the mesopleuron, that is not adjacent to the mesocoxa, but attached to it by the mesocoxal muscle. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 The sclerite that is continuous with the basal mesocoxal conjunctiva and the basal wing conjunctiva and contains the mesofurca. mesopectus imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The sclerite that is continuous with the basal mesocoxal conjunctiva and the basal wing conjunctiva and contains the mesofurca. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 mesopectus 2020-11-11 The trochantin that is located on the ventro-lateral region of the mesothorax and is attached to a mesocoxa and surrounded by the basal mesocoxal conjunctiva. mesotrochantin jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The trochantin that is located on the ventro-lateral region of the mesothorax and is attached to a mesocoxa and surrounded by the basal mesocoxal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 mesotrochantin 2020-11-11 imiko https://orcid.org/0000-0003-2938-9075 The trochantin that is located on the ventro-lateral region of the prothorax and is attached to a procoxa and surrounded by the basal procoxal conjunctiva. protrochantin imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The trochantin that is located on the ventro-lateral region of the prothorax and is attached to a procoxa and surrounded by the basal procoxal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 protrochantin 2020-11-11 The trochantin that is located on the ventro-lateral region of the metathorax and is attached to a metacoxa and surrounded by the basal metacoxal conjunctiva. metatrochantin imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The trochantin that is located on the ventro-lateral region of the metathorax and is attached to a metacoxa and surrounded by the basal metacoxal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 metatrochantin 2020-11-11 The sclerite of the labium that is connected to the mentum by the mental-premental conjunctiva, to the palpiger by the premental-palpigeral conjunctiva, to the paraglossa by the premental-paraglossal conjunctiva, and to the glossa by the premental-glossal conjunctiva. prementum imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The sclerite of the labium that is connected to the mentum by the mental-premental conjunctiva, to the palpiger by the premental-palpigeral conjunctiva, to the paraglossa by the premental-paraglossal conjunctiva, and to the glossa by the premental-glossal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-02-19 prementum Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Prementum: distal main element of labium, bearing the endite lobes (glossa and paraglossa) and the labial palp." The sclerite that is posterior to the pronotum and receives the site of attachment of the dilutor muscle of the first thoracic spiracle. prepectus imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The sclerite that is posterior to the pronotum and receives the site of attachment of the dilutor muscle of the first thoracic spiracle. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 prepectus 2020-11-11 The notum or sclerite on the dorsal region of the prothorax that is attached to cranial muscles, procoxal muscles, contiuous posterioirly with the neck membrane and with pronoto-propleural conjunctiva and not adjacent (not touching) to the procoxa. pronotum imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The notum or sclerite on the dorsal region of the prothorax that is attached to cranial muscles, procoxal muscles, contiuous posterioirly with the neck membrane and with pronoto-propleural conjunctiva and not adjacent (not touching) to the procoxa. imiko https://orcid.org/0000-0003-2938-9075 2022-03-09 2021-03-18 pronotum Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Pronotum: prothoracic tergum." The cuticle of the mere that is part of the labial palpus. cuticle of labial palpomere jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the mere that is part of the labial palpus. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-21 cuticle of labial palpomere 2021-12-08 The sclerite on the ventral region of the prothorax that bears the profurca and is attached to the propleuro-prosternal conjunctiva. prosternum imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The sclerite on the ventral region of the prothorax that bears the profurca and is attached to the propleuro-prosternal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-09 The sclerite that is cylindrical and encircles and is encircled by conjunctiva. ring sclerite imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 The sclerite that is cylindrical and encircles and is encircled by conjunctiva. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 The ring sclerite that is part of an appendage and is attached to muscle. cuticle of appendage segment imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The ring sclerite that is part of an appendage and is attached to muscle. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 cuticle of appendage segment 2021-12-08 The cuticle of the segment of the mid leg that is attached to the latero-ventral region of the mesothorax by the basal mesocoxal conjunctiva and to the mesotrochanter by the mesocoxal-mesotrochanteral conjunctiva. cuticle of mesocoxa imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of the mid leg that is attached to the latero-ventral region of the mesothorax by the basal mesocoxal conjunctiva and to the mesotrochanter by the mesocoxal-mesotrochanteral conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of mesocoxa 2021-12-08 The cuticle of the segment of the hind leg that is attached to the latero-ventral region of the metathorax by the basal metacoxal conjunctiva and to the metatrochanter by the metacoxal-metatrochanteral conjunctiva. cuticle of metacoxa imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of the hind leg that is attached to the latero-ventral region of the metathorax by the basal metacoxal conjunctiva and to the metatrochanter by the metacoxal-metatrochanteral conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of metacoxa 2021-12-08 The cuticle of the segment of the fore leg that is attached to the latero-ventral region of the prothorax by the basal procoxal conjunctiva and to the protrochanter by the procoxal-protrochanteral conjunctiva. cuticle of procoxa imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of the fore leg that is attached to the latero-ventral region of the prothorax by the basal procoxal conjunctiva and to the protrochanter by the procoxal-protrochanteral conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of procoxa 2021-12-08 The cuticle of the segment of a fore leg attached to the distal margin of the profemur by the profemoro-protibial conjunctiva and to the proximal margin of the protarsus by the protibio-protarsal conjunctiva. cuticle of protibia jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a fore leg attached to the distal margin of the profemur by the profemoro-protibial conjunctiva and to the proximal margin of the protarsus by the protibio-protarsal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-03 cuticle of protibia 2021-12-08 The cuticle of the segment of a mid leg attached to the distal margin of the mesofemur by the mesofemoro-mesotibial conjunctiva and to the proximal margin of the mesotarsus by the mesotibio-mesotarsal conjunctiva. cuticle of mesotibia jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a mid leg attached to the distal margin of the mesofemur by the mesofemoro-mesotibial conjunctiva and to the proximal margin of the mesotarsus by the mesotibio-mesotarsal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-03 cuticle of mesotibia 2021-12-08 The cuticle of the segment of a hind leg attached to the distal margin of the metafemur by the metafemoro-metatibial conjunctiva and to the proximal margin of the metatarsus by the metatibio-metatarsal conjunctiva. cuticle of metatibia jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a hind leg attached to the distal margin of the metafemur by the metafemoro-metatibial conjunctiva and to the proximal margin of the metatarsus by the metatibio-metatarsal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-03 cuticle of metatibia 2021-12-08 The cuticle of the segment of a fore leg attached to the distal margin of the protrochanter by the protrochantero-profemoral conjunctiva and to the proximal margin of the protibia by the profemoro-protibial conjunctiva. cuticle of profemur jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a fore leg attached to the distal margin of the protrochanter by the protrochantero-profemoral conjunctiva and to the proximal margin of the protibia by the profemoro-protibial conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of profemur 2021-12-08 The cuticle of the segment of a mid leg attached to the distal margin of the mesotrochanter by the mesotrochantero-mesofemoral conjunctiva and to the proximal margin of the mesotibia by the mesofemoro-mesotibial conjunctiva. cuticle of mesofemur jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a mid leg attached to the distal margin of the mesotrochanter by the mesotrochantero-mesofemoral conjunctiva and to the proximal margin of the mesotibia by the mesofemoro-mesotibial conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of mesofemur 2021-12-08 The cuticle of the segment of a hind leg attached to the distal margin of the metatrochanter by the metatrochantero-metafemoral conjunctiva and to the proximal margin of the metatibia by the metafemoro-metatibial conjunctiva. cuticle of metafemur jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a hind leg attached to the distal margin of the metatrochanter by the metatrochantero-metafemoral conjunctiva and to the proximal margin of the metatibia by the metafemoro-metatibial conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of metafemur 2021-12-08 The ring sclerite that is part of an appendage and is not attached to somatic muscle. cuticle of mere imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The ring sclerite that is part of an appendage and is not attached to somatic muscle. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-21 cuticle of mere 2021-12-08 The cuticle of the mere that is part of the tarsus. cuticle of tarsomere imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the mere that is part of the tarsus. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-21 cuticle of tarsomere "Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Tarsomere: subelement of tarsus in Insecta; number often taxon-specific, sometimes differing on legs of different segments (diagnostic value: tarsal formula)." 2021-12-08 The cuticle of the segment of a leg attached to the distal margin of the femur by the femoro-tibial conjunctiva and to the proximal margin of the tarsus by the tibio-tarsal conjunctiva. cuticle of tibia jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a leg attached to the distal margin of the femur by the femoro-tibial conjunctiva and to the proximal margin of the tarsus by the tibio-tarsal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-04-03 cuticle of tibia Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Tibia: 4th element of leg; usually cylindrical and equipped with paired terminal spurs, often with rows of spines." 2021-12-08 The cuticle of the segment of a leg attached to the distal margin of the trochanter by the trochantero-femoral conjunctiva and to the proximal margin of the tibia by the femoro-tibial conjunctiva. cuticle of femur jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of a leg attached to the distal margin of the trochanter by the trochantero-femoral conjunctiva and to the proximal margin of the tibia by the femoro-tibial conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of femur Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Femur: 3rd element of leg, often largest part." 2021-12-08 The cuticle of the segment of the leg that is attached to the latero-ventral region of the insect thorax by the basal coxal conjunctiva and to the trochanter by the coxal-trochanteral conjunctiva. cuticle of coxa imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the segment of the leg that is attached to the latero-ventral region of the insect thorax by the basal coxal conjunctiva and to the trochanter by the coxal-trochanteral conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-03-18 cuticle of coxa Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Coxa: basal element of leg; articulated with pleural, sternal and usually also trochantinal elements of thoracic segment." 2021-12-08 The somatic muscle that is attached to the head capsule. insect cranial muscle lagonzalezmo https://orcid.org/0000-0002-9136-9932 2021-12-13 lagonzalezmo https://orcid.org/0000-0002-9136-9932 The somatic muscle that is attached to the head capsule. lagonzalezmo https://orcid.org/0000-0002-9136-9932 2021-04-04 The somatic muscle that is attached to the head capsule and the antenna. cranio-antennal muscle lagonzalezmo https://orcid.org/0000-0002-9136-9932 lagonzalezmo https://orcid.org/0000-0002-9136-9932 The somatic muscle that is attached to the head capsule and the antenna. lagonzalezmo https://orcid.org/0000-0002-9136-9932 2021-12-13 2021-04-04 The somatic muscle that is attached to the head capsule and the insect mandible. cranio-mandibular muscle imiko https://orcid.org/0000-0003-2938-9075 lagonzalezmo https://orcid.org/0000-0002-9136-9932 The somatic muscle that is attached to the head capsule and the insect mandible. lagonzalezmo https://orcid.org/0000-0002-9136-9932 2021-12-13 2021-04-04 The somatic muscle that is attached to the head capsule and the labium. cranio-labial muscle lagonzalezmo https://orcid.org/0000-0002-9136-9932 lagonzalezmo https://orcid.org/0000-0002-9136-9932 The somatic muscle that is attached to the head capsule and the labium. lagonzalezmo https://orcid.org/0000-0002-9136-9932 2021-04-04 The somatic muscle that is attached to the head capsule and the labrum. cranio-labral muscle lagonzalezmo https://orcid.org/0000-0002-9136-9932 lagonzalezmo https://orcid.org/0000-0002-9136-9932 The somatic muscle that is attached to the head capsule and the labrum. lagonzalezmo https://orcid.org/0000-0002-9136-9932 2021-12-13 2021-04-04 The coxal muscle of the mesocoxa. mesocoxal muscle imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The coxal muscle of the mesocoxa. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 mesocoxal muscle 2020-11-11 The somatic muscle that inserts in the coxa. All of the coxal muscles, except the second sternal-metacoxal muscle, are attached to the thorax. coxal muscle imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The somatic muscle that inserts in the coxa. imiko https://orcid.org/0000-0003-2938-9075 2021-12-13 2021-04-21 All of the coxal muscles, except the second sternal-metacoxal muscle, are attached to the thorax. imiko https://orcid.org/0000-0003-2938-9075 The cuticle of the mouthpart appendage composed of the cuticle of submentum, which is attached by the submental-mental conjunctiva to the cuticle of mentum, which is attached by the mental-premental conjunctiva to the cuticle of prementum, which is attached to the cuticle of palpiger by the premental-palpigeral conjunctiva, the cuticle of paraglossa by the premental-paraglossal conjunctiva, and the cuticle of glossa by the premental-glossal conjunctiva; the cuticle of palpiger is attached by the palpigero-palpal conjunctiva to the cuticle of labial palpus. cuticle of labium imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The cuticle of the mouthpart appendage composed of the cuticle of submentum, which is attached by the submental-mental conjunctiva to the cuticle of mentum, which is attached by the mental-premental conjunctiva to the cuticle of prementum, which is attached to the cuticle of palpiger by the premental-palpigeral conjunctiva, the cuticle of paraglossa by the premental-paraglossal conjunctiva, and the cuticle of glossa by the premental-glossal conjunctiva; the cuticle of palpiger is attached by the palpigero-palpal conjunctiva to the cuticle of labial palpus. jgiron https://orcid.org/0000-0002-0851-6883 2021-12-08 2021-02-19 cuticle of labium Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "The labium or lower lip forms the posterior (orthognathous head) or ventral (prognathous head) closure of the preoral space and of the salivarium. It is homologous to the maxilla (2nd maxilla) of crustaceans, but its proximal parts form a structural unit without a recognizable median line or suture." 2021-12-08 The elastic cuticle of the head capsule that is transparent and covers the eye. eye cuticle imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 imiko https://orcid.org/0000-0003-2938-9075 The elastic cuticle of the head capsule that is transparent and covers the eye. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-21 eye cuticle 2020-11-11 The resilin rich region that connects two sclerites. insect ligament imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The resilin rich region that connects two sclerites. imiko https://orcid.org/0000-0003-2938-9075 2021-04-21 insect ligament Modified 2023-01-09 to specify insect ligament. jgiron https://orcid.org/0000-0002-0851-6883 2020-11-11 The apodeme of elastic cuticle that is continuous with somatic muscle. The usually cylindircal evagination of the cuticle that is resilin rich and is continuous with somatic muscles. cuticular tendon imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The apodeme of elastic cuticle that is continuous with somatic muscle. 2022-06-22 jgiron https://orcid.org/0000-0002-0851-6883 The usually cylindircal evagination of the cuticle that is resilin rich and is continuous with somatic muscles. imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 cuticular tendon Klass K-D (2001) The female abdomen of the viviparous earwig Hemimerus vosseleri (Insecta: Dermaptera: Hemimeridae), with a discussion of the postgenital abdomen of Insecta. Zoological Journal of the Linnean Society 131: 251–307. https://doi.org/10.1111/j.1096-3642.2001.tb02239.x "tendon is used herein to designate membranous internal cuticular projections" The branching invagination of elastic cuticle that is cylindrical and contains taenidia. insect trachea imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 imiko https://orcid.org/0000-0003-2938-9075 The branching invagination of elastic cuticle that is cylindrical and contains taenidia. imiko https://orcid.org/0000-0003-2938-9075 2020-11-11 insect trachea Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Trachea: tube-shaped elements of the tracheal system." Modified 2023-01-09 to specify insect trachea. jgiron https://orcid.org/0000-0002-0851-6883 The conjunctiva of the insect head that is attached to the salivarium and to the oral foraminal conjunctiva. hypopharynx imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The conjunctiva of the insect head that is attached to the salivarium and to the oral foraminal conjunctiva. jgiron https://orcid.org/0000-0002-0851-6883 2021-02-19 hypopharynx Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. https://doi.org/10.1515/9783110264043 "Hypopharynx: median unpaired lobe between mouthparts and epipharynx; anterior (dorsal) surface continuous with anterior pharynx." The conjunctiva of the insect thorax that joins the mesopleuron and the metapleuron. mesopleuro-metapleural conjunctiva imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The conjunctiva of the insect thorax that joins the mesopleuron and the metapleuron. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-09 The conjunctiva of the mesothorax that joins the metasternum and the metacoxa. metasterno-metacoxal conjunctiva imiko https://orcid.org/0000-0003-2938-9075 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The conjunctiva of the mesothorax that joins the metasternum and the metacoxa. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-09 The conjunctiva of the prothorax that joins the prosternum and the procoxa. prosternal-procoxal conjunctiva jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 jgiron https://orcid.org/0000-0002-0851-6883 The conjunctiva of the prothorax that joins the prosternum and the procoxa. jgiron https://orcid.org/0000-0002-0851-6883 2021-04-09 The conjunctiva of the metathorax that joins the metapleuron and the metacoxa. metapleuro-metacoxal co