{
  "cohort_contract": {
    "Distributed Agents": "three-run framework cohort from the 2026-08-26 odd-seed export",
    "Codex": "three-run framework cohort from the 2026-08-26 odd-seed export",
    "note": "All agent answers contain 50 non-seed predictions. Deterministic rankings were converted to the same contract by removing the 50 visible odd-ranked seeds before selecting their first 50 candidates."
  },
  "cohorts": {
    "Distributed Agents": {
      "hits_at_50": [
        19,
        18,
        17
      ],
      "median_recall_at_50": 0.36,
      "recall_at_50": [
        0.38,
        0.36,
        0.34
      ],
      "runs": [
        {
          "answer_sha256": "b34e07cb12b6153ff1c314c31a43dfc0789b8c63c244eb6f7cacac8e246704ee",
          "path": "[local file: rep1]"
        },
        {
          "answer_sha256": "b2753359d56c91777eb7354f96bdf7c6b7cfc101f0af4f49e336b8037a605ef9",
          "path": "[local file: rep2]"
        },
        {
          "answer_sha256": "d6af50752d2426e7b8cdbc6dd007c983c3f718ae20c32323793961554a3fb0a1",
          "path": "[local file: rep3]"
        }
      ]
    },
    "Codex": {
      "hits_at_50": [
        9,
        12,
        9
      ],
      "median_recall_at_50": 0.18,
      "recall_at_50": [
        0.18,
        0.24,
        0.18
      ],
      "runs": [
        {
          "answer_sha256": "83504ecb9cbb312550a3bd5cc03b10bf7c759b96fd5fcdd5050de409a3193cae",
          "path": "[local file: rep1]"
        },
        {
          "answer_sha256": "8b7225657c04d5c76a820228c51be3b995b614fc611c20e5c87bae584555dbfb",
          "path": "[local file: rep2]"
        },
        {
          "answer_sha256": "1c9834a1a24b6044db7575528cc11b02326ec44f61eb3b792ccf9084882b2179",
          "path": "[local file: rep3]"
        }
      ]
    },
    "DepMap": {
      "hits_at_50": [
        13
      ],
      "implementation": "negative pan-cancer median Chronos gene effect",
      "median_recall_at_50": 0.26,
      "ranking_artifacts": [
        {
          "path": "[local file: depmap_top100_annotated.csv]",
          "sha256": "8979587b4476d7d1eb4e778b1ada03589c05d14410bbc157bcdbbd1f1cb25236"
        }
      ],
      "recall_at_50": [
        0.26
      ],
      "source_system": "DepMap cancer cell lines"
    },
    "Top DEG": {
      "hits_at_50": [
        7
      ],
      "implementation": "151 TH survivor-cell DEG count at adjusted p < 0.05; ties by summed then mean absolute log fold-change",
      "median_recall_at_50": 0.14,
      "ranking_artifacts": [
        {
          "path": "[local file: complete_starting_deg_ranking.tsv]",
          "sha256": "40084ce5e00af5dca9b82d52b43ca472c431c832950e029ccff9cad5f56bcddd"
        }
      ],
      "recall_at_50": [
        0.14
      ],
      "source_system": "same-experiment differential-expression table"
    }
  },
  "cutoffs": [
    5,
    10,
    15,
    20,
    25,
    30,
    35,
    40,
    45,
    50
  ],
  "schema_version": "depletion-recall-comparison-v1",
  "task": "q7-depletion-odd-seed",
  "truth": {
    "path": "[local file: top150_depletion_151_TH_Prkcd_Grin2c_Glut_predicted_group.csv]",
    "sha256": "010909c44c65491d86d69ed6a567b8b00d4316338cd1fbd35984b4cef21c7441"
  },
  "truth_count": 50,
  "truth_definition": "50 even-ranked held-out targets from the canonical Fisher top-100 depletion ranking for 151 TH Prkcd Grin2c Glut"
}