{
  "status": "complete",
  "comparison_design": {
    "reports_per_arm": 150,
    "shared_underlying_response_genes": 150,
    "whole_report_blocks": true,
    "reports_split_across_packets": false,
    "arm_visible_to_grader": false,
    "reported_flag_visible_to_grader": false,
    "shuffle_report_generation_matched": true,
    "unshuffled_generation_matched": false,
    "unshuffled_generation": "260713",
    "shuffle_generation": "260730",
    "excluded_source_finding_types": [
      "buffered_response",
      "negative_result",
      "therapeutic_direction_warning"
    ]
  },
  "n_classified_findings": 2610,
  "admissibility_counts": {
    "uninterpretable_or_underpowered": 492,
    "load_bearing": 1649,
    "over_eager": 158,
    "evidence_only": 311
  },
  "retained_findings_by_layer_and_arm": {
    "primary": {
      "Unshuffled": 488,
      "Within-screen shuffled": 600,
      "Out-of-screen shuffled": 561
    },
    "sensitivity": {
      "Unshuffled": 624,
      "Within-screen shuffled": 685,
      "Out-of-screen shuffled": 649
    }
  },
  "placement_counts_by_layer_and_arm": {
    "primary": {
      "Unshuffled": 1787,
      "Within-screen shuffled": 2871,
      "Out-of-screen shuffled": 2977
    },
    "sensitivity": {
      "Unshuffled": 2295,
      "Within-screen shuffled": 3367,
      "Out-of-screen shuffled": 3456
    }
  },
  "finding_max_signal_primary": {
    "n_assigned_by_arm": {
      "Unshuffled": 472,
      "Within-screen shuffled": 600,
      "Out-of-screen shuffled": 561
    },
    "n_unassigned_by_arm": {
      "Unshuffled": 16,
      "Within-screen shuffled": 0,
      "Out-of-screen shuffled": 0
    },
    "definition": "One load-bearing finding per vote; maximum FDR<0.1 DEG count among its listed cell types."
  },
  "positive_pair_coverage_primary": {
    "Unshuffled": {
      "n_positive_target_celltype_pairs": 1124,
      "n_pairs_covered_by_primary_finding": 638,
      "percent_pairs_covered": 56.762,
      "n_pairs_uncovered": 486,
      "n_positive_cell_type_categories": 23,
      "n_cell_type_categories_covered": 22,
      "uncovered_cell_type_categories_json": "[\"017 CA3 CA2-FC DG Glut\"]",
      "n_pairs_with_multiple_findings": 431,
      "percent_all_pairs_with_multiple_findings": 38.345,
      "percent_covered_pairs_with_multiple_findings": 67.555,
      "n_pairs_with_multiple_distinct_flags": 344,
      "percent_all_pairs_with_multiple_distinct_flags": 30.605,
      "percent_covered_pairs_with_multiple_distinct_flags": 53.918
    },
    "Within-screen shuffled": {
      "n_positive_target_celltype_pairs": 1124,
      "n_pairs_covered_by_primary_finding": 856,
      "percent_pairs_covered": 76.157,
      "n_pairs_uncovered": 268,
      "n_positive_cell_type_categories": 23,
      "n_cell_type_categories_covered": 23,
      "uncovered_cell_type_categories_json": "[]",
      "n_pairs_with_multiple_findings": 563,
      "percent_all_pairs_with_multiple_findings": 50.089,
      "percent_covered_pairs_with_multiple_findings": 65.771,
      "n_pairs_with_multiple_distinct_flags": 480,
      "percent_all_pairs_with_multiple_distinct_flags": 42.705,
      "percent_covered_pairs_with_multiple_distinct_flags": 56.075
    },
    "Out-of-screen shuffled": {
      "n_positive_target_celltype_pairs": 1124,
      "n_pairs_covered_by_primary_finding": 933,
      "percent_pairs_covered": 83.007,
      "n_pairs_uncovered": 191,
      "n_positive_cell_type_categories": 23,
      "n_cell_type_categories_covered": 23,
      "uncovered_cell_type_categories_json": "[]",
      "n_pairs_with_multiple_findings": 644,
      "percent_all_pairs_with_multiple_findings": 57.295,
      "percent_covered_pairs_with_multiple_findings": 69.025,
      "n_pairs_with_multiple_distinct_flags": 458,
      "percent_all_pairs_with_multiple_distinct_flags": 40.747,
      "percent_covered_pairs_with_multiple_distinct_flags": 49.089
    }
  },
  "gold_calibration": {
    "n_gold_compared": 148,
    "admissibility_match": {
      "count": 120,
      "fraction": 0.8108
    },
    "source_relation_match": {
      "count": 113,
      "fraction": 0.7635
    },
    "flag_match": {
      "count": 119,
      "fraction": 0.8041
    },
    "primary_gate_match": {
      "count": 126,
      "fraction": 0.8514
    },
    "sensitivity_gate_match": {
      "count": 128,
      "fraction": 0.8649
    },
    "exact_tuple_match": {
      "count": 56,
      "fraction": 0.3784
    },
    "gold_flag_counts": {
      "inferred": 65,
      "agree": 27,
      "no_literature": 55,
      "disagree": 1
    },
    "production_flag_counts": {
      "no_literature": 68,
      "agree": 23,
      "inferred": 54,
      "disagree": 3
    }
  },
  "local_signal_boundaries": {
    "Strong": "≥100 target×cell-type DEGs at FDR<0.1",
    "Moderate": "25–99",
    "Low": "1–24",
    "No local DEGs": "0; absent canonical target×cell pairs are treated as 0"
  }
}