reviewer_id,survey_packet,item_position,comparison_id,comparison_class,target,codex_source_run,codex_rank,display_A_source,display_B_source,raw_display_preference_score,preference_category,codex_title,distributed_agents_title
R01,1,1,comparison_01,match,Dctn1,caveat30_r01,1,Codex,Distributed Agents,4,Distributed Agents,Dctn1 loss selectively activates a neuronal sterol-biosynthesis program,Acute Dctn1 perturbation evokes a recurrent neuronal SREBP2-like sterol-biosynthesis program
R01,1,2,comparison_02,match,Srsf1,caveat30_r01,4,Distributed Agents,Codex,1,Distributed Agents,Srsf1 loss elicits a pan-neuronal splice-factor autoregulatory response,Acute `Srsf1` disruption elicits a recurrent mixed-direction neuronal RNA-processing response
R02,2,1,comparison_03,match,Zfp423,caveat30_r03,25,Distributed Agents,Codex,2,Distributed Agents,Zfp423 loss disrupts Grid2ip/Cd47 and derepresses Ntsr1 in Prkcd/Grin2c thalamic neurons,Acute Zfp423 loss remodels postmitotic Prkcd/Grin2c thalamic neuronal identity and excitability
R02,2,2,comparison_04,match,Prdm10,caveat30_r02,24,Codex,Distributed Agents,3,Tie,"Prdm10 perturbation reveals a conserved Madd, Cadm3, Ptov1, Stmn2, Myt1, and Uchl1 repression signature","Prdm10 disruption reveals a recurrent neuronal adhesion, axonal-support, synaptic, and excitability program"
R03,3,1,comparison_05,match,Elp1,caveat30_r03,14,Codex,Distributed Agents,4,Distributed Agents,Elp1 perturbation activates an amino-acid starvation and integrated-stress-like program in thalamic glutamatergic neurons,Acute Elp1 perturbation activates an ATF4-centered amino-acid-starvation program in postmitotic thalamic neurons
R03,3,2,comparison_06,match,Apc,caveat30_r03,12,Distributed Agents,Codex,2,Distributed Agents,Apc loss activates canonical Wnt feedback in Prkcd/Grin2c thalamic neurons,APC perturbation couples canonical Wnt activation to synaptic and adhesion remodeling in postmitotic thalamic neurons
R04,4,1,comparison_07,match,U2af2,caveat30_r03,22,Distributed Agents,Codex,3,Tie,U2af2 perturbation depresses spliceosomal and calcium-handling genes in thalamic and midbrain neurons,U2af2 disruption elicits recurrent feedback across neuronal RNP and RNA-processing genes
R04,4,2,comparison_08,match,Tpr,caveat30_r01,11,Codex,Distributed Agents,4,Distributed Agents,Tpr loss induces a nuclear-transport transcriptional program centered on Ranbp6 and Xpo1,Acute Tpr disruption elicits a recurrent neuronal nuclear-transport and RNA-processing response
R05,5,1,comparison_09,match,Rnpc3,caveat30_r03,21,Codex,Distributed Agents,4,Distributed Agents,"Rnpc3 loss creates a core spliceosome response centered on Mapk8, Ap2a1, Wdfy1, Pcyt2, and Pten",Rnpc3 disruption produces recurrent Mapk8 and Pcyt2 induction across postnatal neuronal groups
R05,5,2,comparison_10,match,Kansl1,caveat30_r03,16,Distributed Agents,Codex,3,Tie,Kansl1 loss perturbs midbrain lysosomal and Golgi trafficking transcripts,Acute neuronal `Kansl1` perturbation depresses autophagy–lysosome and membrane-trafficking transcripts across neuronal classes
R06,6,1,comparison_11,refinement,Rab7,caveat30_r01,19,Distributed Agents,Codex,2,Distributed Agents,Rab7 loss elicits a lysosomal hydrolase and sterol-response state,Recurrent lysosomal and vacuolar-acidification gene induction after neuronal Rab7 perturbation
R06,6,2,comparison_12,refinement,Ogt,caveat30_r01,12,Codex,Distributed Agents,1,Codex,Ogt loss represses RNA-processing and cholesterol-turnover transcripts while relieving Xpo1,Acute neuronal `Ogt` loss evokes a recurrent RNA-processing and export signature
R07,7,1,comparison_13,refinement,Wdr26,caveat30_r01,2,Codex,Distributed Agents,3,Tie,Wdr26 loss produces a cerebellar GABA channel-and-splicing signature,Bidirectional receptor and ion-channel repatterning after `Wdr26` perturbation in cerebellar GABAergic neurons
R07,7,2,comparison_14,refinement,Thap11,caveat30_r03,9,Distributed Agents,Codex,2,Distributed Agents,Thap11 perturbation reveals a conserved Rabac1-Sdccag8-Gdap1 mitochondrial/ciliary module,THAP11 loss reveals persistent mitochondrial electron-transport dependence in postmitotic neurons
R08,8,1,comparison_15,refinement,Naa20,caveat30_r01,10,Distributed Agents,Codex,2,Distributed Agents,NatB catalytic-subunit loss represses a Peg3-Kifc2-Snhg11 program in many neurons,A recurrent RNA-processing response to neuronal Naa20 perturbation
R08,8,2,comparison_16,refinement,Tsc1,caveat30_r01,3,Codex,Distributed Agents,2,Codex,Acute Tsc1 and Tsc2 loss couples mTOR derepression to a sterol-lysosome module in postnatal neurons,Acute *Tsc1* perturbation repeatedly induces a neuronal sterol-biosynthesis program
R09,9,1,comparison_17,refinement,Tardbp,caveat30_r01,25,Codex,Distributed Agents,3,Tie,"TDP-43 loss induces Ppp6c, Gabpa, and trafficking transcripts while repressing Snrnp70",Tardbp loss recurrently increases endomembrane transcripts while repressing Snrnp70 across neuronal classes
R09,9,2,comparison_18,refinement,Uba5,caveat30_r01,7,Distributed Agents,Codex,2,Distributed Agents,Uba5 loss links neuronal UFMylation to mitochondrial translation and V-ATPase repression,Uba5 loss elicits recurrent mitochondrial and oxidative-phosphorylation transcriptional remodeling in postmitotic neurons
R10,10,1,comparison_19,refinement,Rora,caveat30_r01,24,Distributed Agents,Codex,1,Distributed Agents,"Rora loss acutely represses Prkcg, Rasa4, Tnnt1, and Pcp4 in Grin2c thalamic neurons",Acute *Rora* perturbation tilts PKC–Ras–Rap–Rho signaling in Prkcd/Grin2c thalamic neurons
R10,10,2,comparison_20,refinement,Atp6v0c,caveat30_r01,18,Codex,Distributed Agents,4,Distributed Agents,Atp6v0c loss coordinately reduces V-ATPase and calcium-channel transcripts,Atp6v0c perturbation recurrently co-depletes Atp6v0a1 and exposes a thalamic excitability-associated state
R11,1,1,comparison_01,match,Dctn1,caveat30_r01,1,Codex,Distributed Agents,4,Distributed Agents,Dctn1 loss selectively activates a neuronal sterol-biosynthesis program,Acute Dctn1 perturbation evokes a recurrent neuronal SREBP2-like sterol-biosynthesis program
R11,1,2,comparison_02,match,Srsf1,caveat30_r01,4,Distributed Agents,Codex,2,Distributed Agents,Srsf1 loss elicits a pan-neuronal splice-factor autoregulatory response,Acute `Srsf1` disruption elicits a recurrent mixed-direction neuronal RNA-processing response
R12,2,1,comparison_03,match,Zfp423,caveat30_r03,25,Distributed Agents,Codex,4,Codex,Zfp423 loss disrupts Grid2ip/Cd47 and derepresses Ntsr1 in Prkcd/Grin2c thalamic neurons,Acute Zfp423 loss remodels postmitotic Prkcd/Grin2c thalamic neuronal identity and excitability
R12,2,2,comparison_04,match,Prdm10,caveat30_r02,24,Codex,Distributed Agents,2,Codex,"Prdm10 perturbation reveals a conserved Madd, Cadm3, Ptov1, Stmn2, Myt1, and Uchl1 repression signature","Prdm10 disruption reveals a recurrent neuronal adhesion, axonal-support, synaptic, and excitability program"
R13,3,1,comparison_05,match,Elp1,caveat30_r03,14,Codex,Distributed Agents,5,Distributed Agents,Elp1 perturbation activates an amino-acid starvation and integrated-stress-like program in thalamic glutamatergic neurons,Acute Elp1 perturbation activates an ATF4-centered amino-acid-starvation program in postmitotic thalamic neurons
R13,3,2,comparison_06,match,Apc,caveat30_r03,12,Distributed Agents,Codex,2,Distributed Agents,Apc loss activates canonical Wnt feedback in Prkcd/Grin2c thalamic neurons,APC perturbation couples canonical Wnt activation to synaptic and adhesion remodeling in postmitotic thalamic neurons
R14,4,1,comparison_07,match,U2af2,caveat30_r03,22,Distributed Agents,Codex,2,Distributed Agents,U2af2 perturbation depresses spliceosomal and calcium-handling genes in thalamic and midbrain neurons,U2af2 disruption elicits recurrent feedback across neuronal RNP and RNA-processing genes
R14,4,2,comparison_08,match,Tpr,caveat30_r01,11,Codex,Distributed Agents,5,Distributed Agents,Tpr loss induces a nuclear-transport transcriptional program centered on Ranbp6 and Xpo1,Acute Tpr disruption elicits a recurrent neuronal nuclear-transport and RNA-processing response
R15,5,1,comparison_09,match,Rnpc3,caveat30_r03,21,Codex,Distributed Agents,4,Distributed Agents,"Rnpc3 loss creates a core spliceosome response centered on Mapk8, Ap2a1, Wdfy1, Pcyt2, and Pten",Rnpc3 disruption produces recurrent Mapk8 and Pcyt2 induction across postnatal neuronal groups
R15,5,2,comparison_10,match,Kansl1,caveat30_r03,16,Distributed Agents,Codex,2,Distributed Agents,Kansl1 loss perturbs midbrain lysosomal and Golgi trafficking transcripts,Acute neuronal `Kansl1` perturbation depresses autophagy–lysosome and membrane-trafficking transcripts across neuronal classes
R16,6,1,comparison_11,refinement,Rab7,caveat30_r01,19,Distributed Agents,Codex,1,Distributed Agents,Rab7 loss elicits a lysosomal hydrolase and sterol-response state,Recurrent lysosomal and vacuolar-acidification gene induction after neuronal Rab7 perturbation
R16,6,2,comparison_12,refinement,Ogt,caveat30_r01,12,Codex,Distributed Agents,4,Distributed Agents,Ogt loss represses RNA-processing and cholesterol-turnover transcripts while relieving Xpo1,Acute neuronal `Ogt` loss evokes a recurrent RNA-processing and export signature
R17,7,1,comparison_13,refinement,Wdr26,caveat30_r01,2,Codex,Distributed Agents,5,Distributed Agents,Wdr26 loss produces a cerebellar GABA channel-and-splicing signature,Bidirectional receptor and ion-channel repatterning after `Wdr26` perturbation in cerebellar GABAergic neurons
R17,7,2,comparison_14,refinement,Thap11,caveat30_r03,9,Distributed Agents,Codex,1,Distributed Agents,Thap11 perturbation reveals a conserved Rabac1-Sdccag8-Gdap1 mitochondrial/ciliary module,THAP11 loss reveals persistent mitochondrial electron-transport dependence in postmitotic neurons
R18,8,1,comparison_15,refinement,Naa20,caveat30_r01,10,Distributed Agents,Codex,1,Distributed Agents,NatB catalytic-subunit loss represses a Peg3-Kifc2-Snhg11 program in many neurons,A recurrent RNA-processing response to neuronal Naa20 perturbation
R18,8,2,comparison_16,refinement,Tsc1,caveat30_r01,3,Codex,Distributed Agents,4,Distributed Agents,Acute Tsc1 and Tsc2 loss couples mTOR derepression to a sterol-lysosome module in postnatal neurons,Acute *Tsc1* perturbation repeatedly induces a neuronal sterol-biosynthesis program
R19,9,1,comparison_17,refinement,Tardbp,caveat30_r01,25,Codex,Distributed Agents,4,Distributed Agents,"TDP-43 loss induces Ppp6c, Gabpa, and trafficking transcripts while repressing Snrnp70",Tardbp loss recurrently increases endomembrane transcripts while repressing Snrnp70 across neuronal classes
R19,9,2,comparison_18,refinement,Uba5,caveat30_r01,7,Distributed Agents,Codex,2,Distributed Agents,Uba5 loss links neuronal UFMylation to mitochondrial translation and V-ATPase repression,Uba5 loss elicits recurrent mitochondrial and oxidative-phosphorylation transcriptional remodeling in postmitotic neurons
R20,10,1,comparison_19,refinement,Rora,caveat30_r01,24,Distributed Agents,Codex,2,Distributed Agents,"Rora loss acutely represses Prkcg, Rasa4, Tnnt1, and Pcp4 in Grin2c thalamic neurons",Acute *Rora* perturbation tilts PKC–Ras–Rap–Rho signaling in Prkcd/Grin2c thalamic neurons
R20,10,2,comparison_20,refinement,Atp6v0c,caveat30_r01,18,Codex,Distributed Agents,5,Distributed Agents,Atp6v0c loss coordinately reduces V-ATPase and calcium-channel transcripts,Atp6v0c perturbation recurrently co-depletes Atp6v0a1 and exposes a thalamic excitability-associated state
R21,1,1,comparison_01,match,Dctn1,caveat30_r01,1,Codex,Distributed Agents,2,Codex,Dctn1 loss selectively activates a neuronal sterol-biosynthesis program,Acute Dctn1 perturbation evokes a recurrent neuronal SREBP2-like sterol-biosynthesis program
R21,1,2,comparison_02,match,Srsf1,caveat30_r01,4,Distributed Agents,Codex,5,Codex,Srsf1 loss elicits a pan-neuronal splice-factor autoregulatory response,Acute `Srsf1` disruption elicits a recurrent mixed-direction neuronal RNA-processing response
R22,2,1,comparison_03,match,Zfp423,caveat30_r03,25,Distributed Agents,Codex,1,Distributed Agents,Zfp423 loss disrupts Grid2ip/Cd47 and derepresses Ntsr1 in Prkcd/Grin2c thalamic neurons,Acute Zfp423 loss remodels postmitotic Prkcd/Grin2c thalamic neuronal identity and excitability
R22,2,2,comparison_04,match,Prdm10,caveat30_r02,24,Codex,Distributed Agents,4,Distributed Agents,"Prdm10 perturbation reveals a conserved Madd, Cadm3, Ptov1, Stmn2, Myt1, and Uchl1 repression signature","Prdm10 disruption reveals a recurrent neuronal adhesion, axonal-support, synaptic, and excitability program"
R23,3,1,comparison_05,match,Elp1,caveat30_r03,14,Codex,Distributed Agents,4,Distributed Agents,Elp1 perturbation activates an amino-acid starvation and integrated-stress-like program in thalamic glutamatergic neurons,Acute Elp1 perturbation activates an ATF4-centered amino-acid-starvation program in postmitotic thalamic neurons
R23,3,2,comparison_06,match,Apc,caveat30_r03,12,Distributed Agents,Codex,2,Distributed Agents,Apc loss activates canonical Wnt feedback in Prkcd/Grin2c thalamic neurons,APC perturbation couples canonical Wnt activation to synaptic and adhesion remodeling in postmitotic thalamic neurons
R24,4,1,comparison_07,match,U2af2,caveat30_r03,22,Distributed Agents,Codex,2,Distributed Agents,U2af2 perturbation depresses spliceosomal and calcium-handling genes in thalamic and midbrain neurons,U2af2 disruption elicits recurrent feedback across neuronal RNP and RNA-processing genes
R24,4,2,comparison_08,match,Tpr,caveat30_r01,11,Codex,Distributed Agents,4,Distributed Agents,Tpr loss induces a nuclear-transport transcriptional program centered on Ranbp6 and Xpo1,Acute Tpr disruption elicits a recurrent neuronal nuclear-transport and RNA-processing response
R25,5,1,comparison_09,match,Rnpc3,caveat30_r03,21,Codex,Distributed Agents,4,Distributed Agents,"Rnpc3 loss creates a core spliceosome response centered on Mapk8, Ap2a1, Wdfy1, Pcyt2, and Pten",Rnpc3 disruption produces recurrent Mapk8 and Pcyt2 induction across postnatal neuronal groups
R25,5,2,comparison_10,match,Kansl1,caveat30_r03,16,Distributed Agents,Codex,2,Distributed Agents,Kansl1 loss perturbs midbrain lysosomal and Golgi trafficking transcripts,Acute neuronal `Kansl1` perturbation depresses autophagy–lysosome and membrane-trafficking transcripts across neuronal classes
R26,6,1,comparison_11,refinement,Rab7,caveat30_r01,19,Distributed Agents,Codex,1,Distributed Agents,Rab7 loss elicits a lysosomal hydrolase and sterol-response state,Recurrent lysosomal and vacuolar-acidification gene induction after neuronal Rab7 perturbation
R26,6,2,comparison_12,refinement,Ogt,caveat30_r01,12,Codex,Distributed Agents,4,Distributed Agents,Ogt loss represses RNA-processing and cholesterol-turnover transcripts while relieving Xpo1,Acute neuronal `Ogt` loss evokes a recurrent RNA-processing and export signature
R27,7,1,comparison_13,refinement,Wdr26,caveat30_r01,2,Codex,Distributed Agents,2,Codex,Wdr26 loss produces a cerebellar GABA channel-and-splicing signature,Bidirectional receptor and ion-channel repatterning after `Wdr26` perturbation in cerebellar GABAergic neurons
R27,7,2,comparison_14,refinement,Thap11,caveat30_r03,9,Distributed Agents,Codex,1,Distributed Agents,Thap11 perturbation reveals a conserved Rabac1-Sdccag8-Gdap1 mitochondrial/ciliary module,THAP11 loss reveals persistent mitochondrial electron-transport dependence in postmitotic neurons
R28,8,1,comparison_15,refinement,Naa20,caveat30_r01,10,Distributed Agents,Codex,1,Distributed Agents,NatB catalytic-subunit loss represses a Peg3-Kifc2-Snhg11 program in many neurons,A recurrent RNA-processing response to neuronal Naa20 perturbation
R28,8,2,comparison_16,refinement,Tsc1,caveat30_r01,3,Codex,Distributed Agents,4,Distributed Agents,Acute Tsc1 and Tsc2 loss couples mTOR derepression to a sterol-lysosome module in postnatal neurons,Acute *Tsc1* perturbation repeatedly induces a neuronal sterol-biosynthesis program
R29,9,1,comparison_17,refinement,Tardbp,caveat30_r01,25,Codex,Distributed Agents,5,Distributed Agents,"TDP-43 loss induces Ppp6c, Gabpa, and trafficking transcripts while repressing Snrnp70",Tardbp loss recurrently increases endomembrane transcripts while repressing Snrnp70 across neuronal classes
R29,9,2,comparison_18,refinement,Uba5,caveat30_r01,7,Distributed Agents,Codex,4,Codex,Uba5 loss links neuronal UFMylation to mitochondrial translation and V-ATPase repression,Uba5 loss elicits recurrent mitochondrial and oxidative-phosphorylation transcriptional remodeling in postmitotic neurons
R30,10,1,comparison_19,refinement,Rora,caveat30_r01,24,Distributed Agents,Codex,4,Codex,"Rora loss acutely represses Prkcg, Rasa4, Tnnt1, and Pcp4 in Grin2c thalamic neurons",Acute *Rora* perturbation tilts PKC–Ras–Rap–Rho signaling in Prkcd/Grin2c thalamic neurons
R30,10,2,comparison_20,refinement,Atp6v0c,caveat30_r01,18,Codex,Distributed Agents,2,Codex,Atp6v0c loss coordinately reduces V-ATPase and calcium-channel transcripts,Atp6v0c perturbation recurrently co-depletes Atp6v0a1 and exposes a thalamic excitability-associated state