1 Introduction

In this study we compare a range of polygenic scoring approaches within a reference standardised framework, whereby the polygenic scores are derived using a previously defined set of variants, and LD and minor allele frequency (MAF) are estimated using an ancestry matched reference genotype data sample. This ensures the performance of the methods will hold true when implementing them within a clinical context, which will require reference-standardisation of polygenic scoring.


2 Aims

  1. Compare the predictive utility of polygenic scores derived using a range of methods.
  2. Compare predictive utility of models including multiple PRSs based on difference parameters, to those using a single PRS selected using 10-fold cross-validation or pseudo-validation.


3 Methods

3.1 Samples

  • UK Biobank
  • TEDS


3.2 Outcomes

  • UK Biobank
    • Depression (binary)
    • Intelligence (continuous)
    • Body mass index (BMI - continuous)
    • Height (continuous)
    • Coronary Artery Disease (CAD - Binary)
    • Type II Diabetes (T2D - Binary)
    • Inflammatory Bowel Disorder (IBD - Binary)
    • Rheumatoid arthritis (RheuArth - Binary)
    • Multiple Slerosis (MultiScler - Binary)
    • Prostate Cancer (Binary)
    • Breast Cancer (Binary)
  • TEDS
    • ADHD traits (continuous)
    • Height (continuous)
    • Body mass index (BMI - continuous)
    • GCSE scores (continuous)


3.3 Genotypic data

Both target sample underwent stringent quality control prior to imputation using the HRC-reference. After imputation, genotypes were converted to PLINK hard-calls, and only HapMap3 SNPs were retained. Eureopean individuals within the target samples were identified and retained if they were within the 3SD of the 1KG European mean of the first 100 principal components.


3.4 GWAS summary statistics

For each target phenotype, the largest independent phenotype-matched GWAS was selected for calculating polygenic scores. More information can be found in the table below.

Preparing GWAS sumstats table for UK Biobank phenotypes

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Phenotype_prep.config')
source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config')

library(data.table)

pheno<-fread('/users/k1806347/brc_scratch/Data/GWAS_sumstats/QC_sumstats_list_270121.csv')

ukb_pheno=c('Depression','Intelligence','BMI','Height','T2D','CAD','IBD','MultiScler','RheuArth','Breast_Cancer','Prostate_Cancer')
ukb_gwas=c('DEPR06','COLL01','BODY04','HEIG03','DIAB05','COAD01','CROH01','SCLE03','RHEU02','BRCA01','PRCA01')
ukb_prev=c(0.15,NA,NA,NA,0.05,0.03,0.013,0.00164,0.005,0.125,0.125)
ukb_dat<-data.frame(pheno=ukb_pheno,gwas=ukb_gwas,prev=ukb_prev)

pheno_ukb<-pheno[(pheno$code %in% ukb_gwas),]
pheno_ukb<-pheno_ukb[,c('code','phenotype_name','reference_year','pmid','n_cases','n_controls','n_total')]
names(pheno_ukb)<-c('code','trait','year','PMID','Ncases','Ncontrols','sample_size_discovery')

ldsc_res<-NULL
for(i in ukb_gwas){
  tmp<-read.table(paste0(gwas_rep_munged,'/',i,'_herit.log'), sep='&')
}

pheno_ukb$ldsc_h2_observed<-NA
pheno_ukb$ldsc_h2_se<-NA
pheno_ukb$ldsc_lambda_GC<-NA
pheno_ukb$ldsc_intercept<-NA
pheno_ukb$ldsc_intercept_se<-NA

ldsc_logs<-list.files(path='/scratch/groups/ukbiobank/sumstats/munged', pattern='_herit.log')
ldsc_logs<-gsub('_herit.log','',ldsc_logs)

for(i in 1:dim(pheno_ukb)[1]){
  if((pheno_ukb$code[i] %in% ldsc_logs)){
    ldsc_logs_i<-read.fwf(paste0(gwas_rep_munged,'/',pheno_ukb$code[i],'_herit.log'),widths = 1000000)
        
    pheno_ukb$ldsc_h2_observed[i]<-as.numeric(gsub(' .*','', gsub('Total Observed scale h2: ','',ldsc_logs_i[grepl('Total Observed scale h2: ', ldsc_logs_i$V1),])))
    pheno_ukb$ldsc_h2_se[i]<-as.numeric(gsub("\\)",'', gsub(".*\\(",'', gsub('Total Observed scale h2: ','',ldsc_logs_i[grepl('Total Observed scale h2: ', ldsc_logs_i$V1),]))))
    pheno_ukb$ldsc_lambda_GC[i]<-as.numeric(gsub('Lambda GC: ','',ldsc_logs_i[grepl('Lambda GC: ', ldsc_logs_i$V1),]))
    pheno_ukb$ldsc_intercept[i]<-as.numeric(gsub(' .*','', gsub("Intercept: ",'',ldsc_logs_i[grepl("Intercept: ", ldsc_logs_i$V1),])))
    pheno_ukb$ldsc_intercept_se[i]<-as.numeric(gsub("\\)",'', gsub(".*\\(",'', gsub("Intercept: ",'',ldsc_logs_i[grepl("Intercept: ", ldsc_logs_i$V1),]))))
  }
}

pheno_ukb$pop_prev<-ukb_dat$prev[match(pheno_ukb$code, ukb_dat$gwas)]
pheno_ukb$Target_Phenotype<-ukb_dat$pheno[match(pheno_ukb$code, ukb_dat$gwas)]
pheno_ukb$Ncases<-as.numeric(gsub(',','',pheno_ukb$Ncases))
pheno_ukb$Ncontrols<-as.numeric(gsub(',','',pheno_ukb$Ncontrols))
pheno_ukb$samp_prev<-pheno_ukb$Ncases/(pheno_ukb$Ncases+pheno_ukb$Ncontrols)

h2l_R2 <- function(k, r2, p) {
  # K baseline disease risk
  # r2 from a linear regression model attributable to genomic profile risk score
  # P proportion of sample that are cases
  # calculates proportion of variance explained on the liability scale
  #from ABC at http://www.complextraitgenomics.com/software/
  #Lee SH, Goddard ME, Wray NR, Visscher PM. (2012) A better coefficient of determination for genetic profile analysis. Genet Epidemiol. 2012 Apr;36(3):214-24.
  x= qnorm(1-k)
  z= dnorm(x)
  i=z/k
  C= k*(1-k)*k*(1-k)/(z^2*p*(1-p))
  theta= i*((p-k)/(1-k))*(i*((p-k)/(1-k))-x)
  h2l_R2 = C*r2 / (1 + C*theta*r2)
}

se_h2l_R2 <- function(k,h2,se, p) {
  # K baseline disease risk
  # r2 from a linear regression model attributable to genomic profile risk score
  # P proportion of sample that are cases
  # calculates proportion of variance explained on the liability scale
  #from ABC at http://www.complextraitgenomics.com/software/
  #Lee SH, Goddard ME, Wray NR, Visscher PM. (2012) A better coefficient of determination for genetic profile analysis. Genet Epidemiol. 2012 Apr;36(3):214-24.

  #SE on the liability (From a Taylor series expansion)
  #var(h2l_r2) = [d(h2l_r2)/d(R2v)]^2*var(R2v) with d being calculus differentiation
  x= qnorm(1-k)
  z= dnorm(x)
  i=z/k
  C= k*(1-k)*k*(1-k)/(z^2*p*(1-p))
  theta= i*((p-k)/(1-k))*(i*((p-k)/(1-k))-x)
  se_h2l_R2 = C*(1-h2*theta)*se
}

pheno_ukb$ldsc_h2_observed<-as.numeric(pheno_ukb$ldsc_h2_observed)
pheno_ukb$ldsc_h2_se<-as.numeric(pheno_ukb$ldsc_h2_se)

pheno_ukb$h2_liab<-round(h2l_R2(k=pheno_ukb$pop_prev, r2=pheno_ukb$ldsc_h2_observed, p=pheno_ukb$samp_prev),3)
pheno_ukb$h2_liab_se<-round(se_h2l_R2(k=pheno_ukb$pop_prev, h2=pheno_ukb$ldsc_h2_observed, se=pheno_ukb$ldsc_h2_se, p=pheno_ukb$samp_prev),3)

pheno_ukb$ldsc_h2_observed<-paste0(pheno_ukb$ldsc_h2_observed," (", pheno_ukb$ldsc_h2_se,")")
pheno_ukb$ldsc_h2_se<-NULL
pheno_ukb$h2_liab[!is.na(pheno_ukb$Ncases)]<-paste0(pheno_ukb$h2_liab[!is.na(pheno_ukb$Ncases)]," (", pheno_ukb$h2_liab_se[!is.na(pheno_ukb$Ncases)],")")
pheno_ukb$h2_liab_se<-NULL
pheno_ukb$ldsc_intercept<-paste0(pheno_ukb$ldsc_intercept," (", pheno_ukb$ldsc_intercept_se,")")
pheno_ukb$ldsc_intercept_se<-NULL

pheno_ukb$Trait<-c('BMI','CAD','Intelligence',"Crohn's Disease",'Major Depression','T2D','Height','RheuArth','MultiScler','Prostate Cancer','Breast Cancer')
pheno_ukb<-pheno_ukb[match(ukb_dat$gwas,pheno_ukb$code),]

pheno_ukb<-pheno_ukb[,c('Trait','code','trait','year','PMID','Ncases','Ncontrols','sample_size_discovery','ldsc_h2_observed','h2_liab','ldsc_intercept','ldsc_lambda_GC')]
names(pheno_ukb)<-c('Target Phenotype','Code','GWAS Phenotype','Year','PMID','Ncase','Ncontrol','N','h2_obs','h2_liab','Intercept','Lambda')

write.csv(pheno_ukb, '/users/k1806347/brc_scratch/Data/GWAS_sumstats/UKBB_phenotype_GWAS_descrip.csv', row.names=F, quote=F)

Show GWAS for UK Biobank phenotypes

GWAS used for each UK Biobank phenotype
Target Phenotype Code GWAS Phenotype Year PMID Ncase Ncontrol N h2-obs (SE) h2-liab (SE) Intercept Lambda
Major Depression DEPR06 major depressive disorder 2018 29700475 116404 314990 431394 0.0551 (0.0023) 0.085 (0.004) 1.0169 (0.0088) 1.3894
Intelligence COLL01 college completion 2013 23722424 NA NA 95427 0.1048 (0.0075) NA 1.0214 (0.0086) 1.1940
BMI BODY04 BMI 2015 25673413 NA NA 322154 0.1297 (0.0056) NA 0.6729 (0.0076) 1.0772
Height HEIG03 height 2014 25282103 NA NA 253288 0.312 (0.0141) NA 1.3254 (0.0185) 2.0007
T2D DIAB05 diabetes type 2 2017 28566273 26676 132532 159208 0.0781 (0.0053) 0.124 (0.008) 0.9984 (0.0083) 1.1459
CAD COAD01 coronary artery disease 2015 26343387 60801 123504 184305 0.0661 (0.0045) 0.057 (0.004) 0.8875 (0.0074) 1.0466
Crohn’s Disease CROH01 crohn disease 2015 26192919 5956 14927 20883 0.4751 (0.0538) 0.542 (0.059) 1.0316 (0.0092) 1.1396
MultiScler SCLE03 multiple sclerosis 2011 21833088 9772 17376 27148 0.0493 (0.0262) 0.021 (0.012) 1.0599 (0.0085) 1.0375
RheuArth RHEU02 rheumatoid arthritis 2014 24390342 14361 43923 58284 0.1406 (0.0176) 0.102 (0.013) 0.9511 (0.0076) 1.0466
Breast Cancer BRCA01 breast cancer 2017 29059683 122977 105974 228951 0.1326 (0.0108) 0.157 (0.013) 1.1001 (0.0125) 1.3581
Prostate Cancer PRCA01 prostate cancer 2017 29892016 79148 61106 140254 0.1635 (0.0238) 0.198 (0.029) 1.0804 (0.0153) 1.2201

Preparing GWAS sumstats table for TEDS phenotypes

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Phenotype_prep.config')
source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config')

library(data.table)

pheno<-fread('/users/k1806347/brc_scratch/Data/GWAS_sumstats/QC_sumstats_list_270121.csv')

teds_pheno=c('Height21', 'BMI21', 'GCSE', 'ADHD')
teds_gwas=c('HEIG03', 'BODY11', 'EDUC03', 'ADHD04')
teds_prev=c(NA,NA,NA,0.05)
teds_dat<-data.frame(pheno=teds_pheno,gwas=teds_gwas,prev=teds_prev)

pheno_teds<-pheno[(pheno$code %in% teds_gwas),]
pheno_teds<-pheno_teds[,c('code','phenotype_name','reference_year','pmid','n_cases','n_controls','n_total')]
names(pheno_teds)<-c('code','trait','year','PMID','Ncases','Ncontrols','sample_size_discovery')

ldsc_res<-NULL
for(i in teds_gwas){
  tmp<-read.table(paste0(gwas_rep_munged,'/',i,'_herit.log'), sep='&')
}

pheno_teds$ldsc_h2_observed<-NA
pheno_teds$ldsc_h2_se<-NA
pheno_teds$ldsc_lambda_GC<-NA
pheno_teds$ldsc_intercept<-NA
pheno_teds$ldsc_intercept_se<-NA

ldsc_logs<-list.files(path='/scratch/groups/ukbiobank/sumstats/munged', pattern='_herit.log')
ldsc_logs<-gsub('_herit.log','',ldsc_logs)

for(i in 1:dim(pheno_teds)[1]){
  if((pheno_teds$code[i] %in% ldsc_logs)){
    ldsc_logs_i<-read.fwf(paste0(gwas_rep_munged,'/',pheno_teds$code[i],'_herit.log'),widths = 1000000)
        
    pheno_teds$ldsc_h2_observed[i]<-as.numeric(gsub(' .*','', gsub('Total Observed scale h2: ','',ldsc_logs_i[grepl('Total Observed scale h2: ', ldsc_logs_i$V1),])))
    pheno_teds$ldsc_h2_se[i]<-as.numeric(gsub("\\)",'', gsub(".*\\(",'', gsub('Total Observed scale h2: ','',ldsc_logs_i[grepl('Total Observed scale h2: ', ldsc_logs_i$V1),]))))
    pheno_teds$ldsc_lambda_GC[i]<-as.numeric(gsub('Lambda GC: ','',ldsc_logs_i[grepl('Lambda GC: ', ldsc_logs_i$V1),]))
    pheno_teds$ldsc_intercept[i]<-as.numeric(gsub(' .*','', gsub("Intercept: ",'',ldsc_logs_i[grepl("Intercept: ", ldsc_logs_i$V1),])))
    pheno_teds$ldsc_intercept_se[i]<-as.numeric(gsub("\\)",'', gsub(".*\\(",'', gsub("Intercept: ",'',ldsc_logs_i[grepl("Intercept: ", ldsc_logs_i$V1),]))))
  }
}

pheno_teds$pop_prev<-teds_dat$prev[match(pheno_teds$code, teds_dat$gwas)]
pheno_teds$Target_Phenotype<-teds_dat$pheno[match(pheno_teds$code, teds_dat$gwas)]
pheno_teds$Ncases<-as.numeric(gsub(',','',pheno_teds$Ncases))
pheno_teds$Ncontrols<-as.numeric(gsub(',','',pheno_teds$Ncontrols))
pheno_teds$samp_prev<-pheno_teds$Ncases/(pheno_teds$Ncases+pheno_teds$Ncontrols)

h2l_R2 <- function(k, r2, p) {
  # K baseline disease risk
  # r2 from a linear regression model attributable to genomic profile risk score
  # P proportion of sample that are cases
  # calculates proportion of variance explained on the liability scale
  #from ABC at http://www.complextraitgenomics.com/software/
  #Lee SH, Goddard ME, Wray NR, Visscher PM. (2012) A better coefficient of determination for genetic profile analysis. Genet Epidemiol. 2012 Apr;36(3):214-24.
  x= qnorm(1-k)
  z= dnorm(x)
  i=z/k
  C= k*(1-k)*k*(1-k)/(z^2*p*(1-p))
  theta= i*((p-k)/(1-k))*(i*((p-k)/(1-k))-x)
  h2l_R2 = C*r2 / (1 + C*theta*r2)
}

se_h2l_R2 <- function(k,h2,se, p) {
  # K baseline disease risk
  # r2 from a linear regression model attributable to genomic profile risk score
  # P proportion of sample that are cases
  # calculates proportion of variance explained on the liability scale
  #from ABC at http://www.complextraitgenomics.com/software/
  #Lee SH, Goddard ME, Wray NR, Visscher PM. (2012) A better coefficient of determination for genetic profile analysis. Genet Epidemiol. 2012 Apr;36(3):214-24.

  #SE on the liability (From a Taylor series expansion)
  #var(h2l_r2) = [d(h2l_r2)/d(R2v)]^2*var(R2v) with d being calculus differentiation
  x= qnorm(1-k)
  z= dnorm(x)
  i=z/k
  C= k*(1-k)*k*(1-k)/(z^2*p*(1-p))
  theta= i*((p-k)/(1-k))*(i*((p-k)/(1-k))-x)
  se_h2l_R2 = C*(1-h2*theta)*se
}

pheno_teds$ldsc_h2_observed<-as.numeric(pheno_teds$ldsc_h2_observed)
pheno_teds$ldsc_h2_se<-as.numeric(pheno_teds$ldsc_h2_se)

pheno_teds$h2_liab<-round(h2l_R2(k=pheno_teds$pop_prev, r2=pheno_teds$ldsc_h2_observed, p=pheno_teds$samp_prev),3)
pheno_teds$h2_liab_se<-round(se_h2l_R2(k=pheno_teds$pop_prev, h2=pheno_teds$ldsc_h2_observed, se=pheno_teds$ldsc_h2_se, p=pheno_teds$samp_prev),3)

pheno_teds$ldsc_h2_observed<-paste0(pheno_teds$ldsc_h2_observed," (", pheno_teds$ldsc_h2_se,")")
pheno_teds$ldsc_h2_se<-NULL
pheno_teds$h2_liab[!is.na(pheno_teds$Ncases)]<-paste0(pheno_teds$h2_liab[!is.na(pheno_teds$Ncases)]," (", pheno_teds$h2_liab_se[!is.na(pheno_teds$Ncases)],")")
pheno_teds$h2_liab_se<-NULL
pheno_teds$ldsc_intercept<-paste0(pheno_teds$ldsc_intercept," (", pheno_teds$ldsc_intercept_se,")")
pheno_teds$ldsc_intercept_se<-NULL

pheno_teds$Trait<-c("ADHD symptoms",'BMI','GCSE','Height')
pheno_teds<-pheno_teds[match(teds_dat$gwas,pheno_teds$code),]

pheno_teds<-pheno_teds[,c('Trait','code','trait','year','PMID','Ncases','Ncontrols','sample_size_discovery','ldsc_h2_observed','h2_liab','ldsc_intercept','ldsc_lambda_GC')]
names(pheno_teds)<-c('Target Phenotype','Code','GWAS Phenotype','Year','PMID','Ncase','Ncontrol','N','h2_obs','h2_liab','Intercept','Lambda')

write.csv(pheno_teds, '/users/k1806347/brc_scratch/Data/GWAS_sumstats/TEDS_phenotype_GWAS_descrip.csv', row.names=F, quote=F)

Show GWAS for TEDS phenotypes

GWAS used for each TEDS phenotype
Target Phenotype Code GWAS Phenotype Year PMID Ncase Ncontrol N h2-obs (SE) h2-liab (SE) Intercept Lambda
Height HEIG03 height 2014 25282103 NA NA 253288 0.312 (0.0141) NA 1.3254 (0.0185) 2.0007
BMI BODY11 BMI 2018 30124842 NA NA 681275 0.1908 (0.0053) NA 1.1864 (0.0206) 2.7872
GCSE EDUC03 years educational attainment 2018 30038396 NA NA 766345 0.1066 (0.0026) NA 1.0301 (0.0137) 2.0940
ADHD symptoms ADHD04 ADHD 2017 30478444 20183 35191 55374 0.3635 (0.0227) 0.426 (0.026) 1.0295 (0.0096) 1.2431


3.5 Polygenic scoring

Polygenic scores were derived using the following methods:

  1. p-value thresholding and clumping (pT + clump).
  2. lassosum - Lasso-based shrinkage method.
  3. PRScs - Bayesian shrinkage method.
  4. SBLUP - Summary statistic-based BLUP estimates
  5. SBayesR - Bayesian shrinkage method
  6. LDpred - Bayesian shrinkage method
  7. DBSLMM - Bayesian shrinkage method
  8. LDpred2 - Bayesian shrinkage method

Polygenic scores were derived using a reference standardised pipeline. Two references were used for all methods, the European subset of the 1KG reference (described here), and an independant subset of 10K European individuals from UK Biobank (described here). In brief, all scores were derived using HapMap3 SNPs only, modelling LD based on these references Any HapMap3 missing in the target sample are imputed using the reference estimated allele frequency.


3.5.1 UK Biobank

pT + clump: Sparse

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J pt_clump

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer/Scaled_polygenic_scorer.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump/${gwas}/1KGPhase3.w_hm3.${gwas} \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/sbatch.sh

######
# UKBB ref
######

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir -p ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J pt_clump

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer/Scaled_polygenic_scorer.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/pt_clump/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/pt_clump/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/pt_clump/sbatch.sh

pT + clump: Dense

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 25G
#SBATCH -t 72:00:00
#SBATCH -J pt_clump_dense

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_dense/Scaled_polygenic_scorer_dense.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.GWAS_sumstats_clumped.txt \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --prsice_path ${prsice_path} \
    --rscript ${rscript} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/todo.txt | cut -d' ' -f1)%5 ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/sbatch.sh

# BODY04 and PRCA01 aren't finishing
# Run in batches
# Split phenotype files into batches
library(data.table)
source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')
source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config')

pheno<-c('BMI', 'Prostate_Cancer')
for(i in pheno){
  pheno_file<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',i,'.txt'))
  
  pheno_file_split<-split(pheno_file, (as.numeric(rownames(pheno_file))-1) %/% 5000)
  
  for(k in 1:length(pheno_file_split)){
    write.table(pheno_file_split[[k]], paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',i,'.subset_',k,'.txt'), col.names=T, row.names=F, quote=F)
  }
}
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

# BODY04
# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/sbatch_BODY04.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -t 72:00:00
#SBATCH -J pt_clump_dense

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=BODY04
pheno=BMI
subset=${SLURM_ARRAY_TASK_ID}

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_dense/Scaled_polygenic_scorer_dense.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.subset_${subset}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.GWAS_sumstats_clumped.txt \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --prsice_path ${prsice_path} \
    --rscript ${rscript} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/${gwas}.subset_${subset}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-10 ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/sbatch_BODY04.sh


# PRCA01
# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/sbatch_PRCA01.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -t 72:00:00
#SBATCH -J pt_clump_dense

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=PRCA01
pheno=Prostate_Cancer
subset=${SLURM_ARRAY_TASK_ID}

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_dense/Scaled_polygenic_scorer_dense.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.subset_${subset}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.GWAS_sumstats_clumped.txt \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --prsice_path ${prsice_path} \
    --rscript ${rscript} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/${gwas}.subset_${subset}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-10 ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/sbatch_PRCA01.sh

# Combine the score from the different batches
library(data.table)
source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')
source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config')

gwas<-c('BODY04', 'PRCA01')

for(i in gwas){
tmp<-NULL
  for(k in 1:10){
    print(k)
    tmp<-rbind(tmp, fread(paste0(UKBB_output,'/PRS_for_comparison/1KG_ref/pt_clump_dense/',i,'.subset_',k,'/UKBB.subset.w_hm3.',i,'.profiles')))
  }

dir.create(paste0(UKBB_output,'/PRS_for_comparison/1KG_ref/pt_clump_dense/',i))
fwrite(tmp, paste0(UKBB_output,'/PRS_for_comparison/1KG_ref/pt_clump_dense/',i,'/UKBB.subset.w_hm3.',i,'.profiles'), col.names=T, row.names=F, quote=F, sep=' ')
}

pT + clump: Sparse (non-nested)

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J pt_clump_nonnested

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer/Scaled_polygenic_scorer.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_nonnested/${gwas}/1KGPhase3.w_hm3.${gwas} \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_nonnested/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/sbatch.sh

lassosum

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.lassosum_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 15G
#SBATCH -n 5
#SBATCH -J lassosum

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_lassosum/Scaled_polygenic_scorer_lassosum.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/lassosum/${gwas}/1KGPhase3.w_hm3.${gwas} \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/lassosum/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --pheno_name ${gwas} \
    --n_cores 5 \
    --plink ${plink1_9} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/lassosum/sbatch.sh

######
# UKBB ref
######

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.lassosum_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 15G
#SBATCH -n 5
#SBATCH -J lassosum

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_lassosum/Scaled_polygenic_scorer_lassosum.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/lassosum/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/lassosum/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --pheno_name ${gwas} \
    --n_cores 5 \
    --plink ${plink1_9} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/lassosum/sbatch.sh

PRScs

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.PRScs_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J PRScs

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_PRScs/Scaled_polygenic_scorer_PRScs.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/PRScs/${gwas}/1KGPhase3.w_hm3.${gwas} \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/PRScs/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/PRScs/sbatch.sh

SBLUP

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.SBLUP_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBLUP

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBLUP/Scaled_polygenic_scorer_SBLUP.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBLUP/${gwas}/GWAS_sumstats_SBLUP.sblup.cojo \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBLUP/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBLUP/sbatch.sh

######
# UKBB ref
######

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.SBLUP_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBLUP

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBLUP/Scaled_polygenic_scorer_SBLUP.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBLUP/${gwas}/GWAS_sumstats_SBLUP.sblup.cojo \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBLUP/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBLUP/sbatch.sh

SBayesR

########
# 1KG ref
######## 
####
# Standard
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch.sh

####
# P<0.4
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_P4.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_P4/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_P4.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_P4.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_P4.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_P4.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_P4/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_P4/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}_P4/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_P4.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_P4.sh


####
# GCTB v2.03
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTB_203/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTB_203.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}_GCTB_203/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203.txt | cut -d' ' -f1)%5 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTB_203.sh

####
# GCTB v2.03 forced robust parameterisation
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203_robust.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTB_203_robust/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203_robust.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTB_203_robust.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203_robust.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203_robust.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}_GCTB_203_robust/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTB_203_robust.txt | cut -d' ' -f1)%5 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTB_203_robust.sh

########
# GCTB ref
######## 
####
# Standard
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}_GCTBref/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref.sh

####
# P<0.4
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_P4.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_P4/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_P4.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref_P4.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_P4.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_P4.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_P4/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_P4/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}_GCTBref_P4/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_P4.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref_P4.sh

####
# GCTB v2.03
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_GCTB_203/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref_GCTB_203.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}_GCTBref_GCTB_203/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref_GCTB_203.sh

####
# GCTB v2.03 with forced robust mode
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203_robust.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_GCTB_203_robust/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203_robust.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref_GCTB_203_robust.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203_robust.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203_robust.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203_robust/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203_robust/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas}_GCTBref_GCTB_203_robust/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/todo_GCTBref_GCTB_203_robust.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/sbatch_GCTBref_GCTB_203_robust.sh

########################
# Calculate polygenic scores using UKBB reference
########################
####
# Standard
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch.sh

####
# P<0.4
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_P4.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}_P4/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_P4.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch_P4.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_P4.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_P4.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_P4/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_P4/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas}_P4/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_P4.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch_P4.sh

####
# GCTB v2.03
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}_GCTB_203/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch_GCTB_203.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas}_GCTB_203/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch_GCTB_203.sh

####
# GCTB v2.03 robust parameterisation
####
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203_robust.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}_GCTB_203_robust/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203_robust.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch_GCTB_203_robust.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J SBayesR

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203_robust.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203_robust.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/GWAS_sumstats_SBayesR.GW.snpRes \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas}_GCTB_203_robust/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/todo_GCTB_203_robust.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/sbatch_GCTB_203_robust.sh

LDPred

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.LDPred_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J LDPred

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred/Scaled_polygenic_scorer_LDPred.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred/${gwas}/1KGPhase3.w_hm3.${gwas} \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred/sbatch.sh

######
# UKBB ref
######
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.LDPred_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J LDPred

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred/Scaled_polygenic_scorer_LDPred.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred/sbatch.sh

LDPred2

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.LDPred_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -n 6
#SBATCH --nodes 1
#SBATCH -J LDPred2

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred2/Scaled_polygenic_scorer_LDPred2.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred2/${gwas}/1KGPhase3.w_hm3.${gwas} \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred2/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --n_cores 6 \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/todo.txt | cut -d' ' -f1)%5 ${UKBB_output}/PRS_for_comparison/1KG_ref/LDPred2/sbatch.sh

######
# UKBB ref
######
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.LDPred_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -n 6
#SBATCH -J LDPred2

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred2/Scaled_polygenic_scorer_LDPred2.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred2/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred2/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --n_cores 6 \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/LDPred2/sbatch.sh

DBSLMM

########
# 1KG ref
######## 
# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.DBSLMM_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J DBSLMM

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_DBSLMM/Scaled_polygenic_scorer_DBSLMM.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/DBSLMM/${gwas}/1KGPhase3.w_hm3.${gwas}.dbslmm.GW.txt \
    --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/DBSLMM/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/1KG_ref/DBSLMM/sbatch.sh

######
# UKBB ref
######

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

# Create directory
mkdir ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM

# Create file listing GWAS that haven't been processed.
> ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/todo.txt
for i in $(seq 1 11);do
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
if [ ! -f ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.DBSLMM_profiles ]; then
echo ${gwas_i} ${pheno_i} >> ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/todo.txt
fi
done

# Create shell script to run using sbatch
cat > ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/sbatch.sh << 'EOF'
#!/bin/sh

#SBATCH -p shared,brc
#SBATCH --mem 10G
#SBATCH -J DBSLMM

. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config

gwas=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $1}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/todo.txt)
pheno=$(awk -v var="$SLURM_ARRAY_TASK_ID" 'NR == var {print $2}' ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/todo.txt)

echo $gwas
echo $pheno

/users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_DBSLMM/Scaled_polygenic_scorer_DBSLMM.R \
    --target_plink_chr ${UKBB_output}/Genotype/Harmonised/UKBB.w_hm3.QCd.AllSNP.chr \
    --target_keep ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno}.txt \
    --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/DBSLMM/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.dbslmm.GW.txt \
    --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/DBSLMM/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
    --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
    --plink ${plink1_9} \
    --pheno_name ${gwas} \
    --output ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/${gwas}/UKBB.subset.w_hm3.${gwas}

EOF

sbatch --array 1-$(wc -l ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/todo.txt | cut -d' ' -f1)%3 ${UKBB_output}/PRS_for_comparison/UKBB_ref/DBSLMM/sbatch.sh


3.5.2 TEDS

pT + clump: Sparse

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Calculate polygenic scores based on 1KG reference.
n=0
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 5G -p brc,shared -J pTclump /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer/Scaled_polygenic_scorer.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump/${gwas}/1KGPhase3.w_hm3.${gwas} \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/pt_clump/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

# Calculate polygenic scores based on UKBB reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J pTclump /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer/Scaled_polygenic_scorer.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/pt_clump/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/pt_clump/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/pt_clump/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

pT + clump: Dense

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Calculate polygenic scores for for Europeans only for now.
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J PRS_dense /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_dense/Scaled_polygenic_scorer_dense.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.GWAS_sumstats_clumped.txt \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_dense/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --prsice_path ${prsice_path} \
  --rscript ${rscript} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/pt_clump_dense/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

pT + clump: Sparse (non-nested)

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Calculate polygenic scores based on 1KG reference
n=0
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J pTclump /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer/Scaled_polygenic_scorer.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_nonnested/${gwas}/1KGPhase3.w_hm3.${gwas} \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/pt_clump_nonnested/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/pt_clump_nonnested/${gwas}/TEDS.w_hm3.${gwas}.EUR
n=$(($n+1))
done

lassosum

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Calculate scores using the 1KG reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J lassosum /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_lassosum/Scaled_polygenic_scorer_lassosum.R \
  --target_plink_chr /users/k1806347/brc_scratch/Data/TEDS/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/lassosum/${gwas}/1KGPhase3.w_hm3.${gwas} \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/lassosum/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --pheno_name ${gwas} \
  --plink ${plink1_9} \
  --n_cores 1 \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/lassosum/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

# Calculate scores using the UKBB reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J lassosum /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_lassosum/Scaled_polygenic_scorer_lassosum.R \
  --target_plink_chr /users/k1806347/brc_scratch/Data/TEDS/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/lassosum/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/lassosum/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --pheno_name ${gwas} \
  --plink ${plink1_9} \
  --n_cores 1 \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/lassosum/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

PRScs

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Calculate scores using My 1KG reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J PRScs /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_PRScs/Scaled_polygenic_scorer_PRScs.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/PRScs/${gwas}_My1KGRef/1KGPhase3.w_hm3.${gwas} \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/PRScs/${gwas}_My1KGRef/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/PRScs/${gwas}_My1KGRef/TEDS.w_hm3.${gwas}.EUR
done

# Calculate scores using the PRScs 1KG reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J PRScs /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_PRScs/Scaled_polygenic_scorer_PRScs.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/PRScs/${gwas}/1KGPhase3.w_hm3.${gwas} \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/PRScs/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/PRScs/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

SBLUP

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBLUP /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBLUP/Scaled_polygenic_scorer_SBLUP.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBLUP/${gwas}/GWAS_sumstats_SBLUP.sblup.cojo \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBLUP/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBLUP/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBLUP /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBLUP/Scaled_polygenic_scorer_SBLUP.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBLUP/${gwas}/GWAS_sumstats_SBLUP.sblup.cojo \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBLUP/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/SBLUP/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

SBayesR

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

##########################
# Calculate polygenic scores using 1KG reference
##########################
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

# P<0.4
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_P4/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_P4/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}_P4/TEDS.w_hm3.${gwas}.EUR
done

# GCTB v2.03
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}_GCTB_203/TEDS.w_hm3.${gwas}.EUR
done

# GCTB v2.03 forced robust
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}_GCTB_203_robust/TEDS.w_hm3.${gwas}.EUR
done

##########################
# Calculate polygenic scores using UKBB reference
##########################

for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 5G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/SBayesR/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

# P<0.4
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 5G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_P4/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_P4/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/SBayesR/${gwas}_P4/TEDS.w_hm3.${gwas}.EUR
done

# GCTB v2.03
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 5G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/SBayesR/${gwas}_GCTB_203/TEDS.w_hm3.${gwas}.EUR
done

# GCTB v2.03 forced robust
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 5G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/SBayesR/${gwas}_GCTB_203_robust/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/SBayesR/${gwas}_GCTB_203_robust/TEDS.w_hm3.${gwas}.EUR
done

##########################
# Calculate polygenic scores using GCTB reference
##########################

for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}_GCTBref/TEDS.w_hm3.${gwas}.EUR
done

# P<0.4
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_P4/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_P4/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}_GCTBref_P4/TEDS.w_hm3.${gwas}.EUR
done

# GCTB V2.03
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}_GCTBref_GCTB_203/TEDS.w_hm3.${gwas}.EUR
done

# GCTB V2.03 forced robust
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J SBayesR /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_SBayesR/Scaled_polygenic_scorer_SBayesR.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203_robust/GWAS_sumstats_SBayesR.GW.snpRes \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/SBayesR/${gwas}_GCTBref_GCTB_203_robust/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/SBayesR/${gwas}_GCTBref_GCTB_203_robust/TEDS.w_hm3.${gwas}.EUR
done

LDPred

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Calculate scores using the 1KG reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J LDPred /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred/Scaled_polygenic_scorer_LDPred.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred/${gwas}/1KGPhase3.w_hm3.${gwas} \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/LDPred/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

# Calculate scores using the UKBB reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J LDPred /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred/Scaled_polygenic_scorer_LDPred.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/LDPred/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

LDPred2

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Calculate scores using the 1KG reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J LDPred2 /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred2/Scaled_polygenic_scorer_LDPred2.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred2/${gwas}/1KGPhase3.w_hm3.${gwas} \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/LDPred2/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/LDPred2/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

# Calculate scores using the UKBB reference
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 10G -p brc,shared -J LDPred2 /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_LDPred2/Scaled_polygenic_scorer_LDPred2.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred2/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas} \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/LDPred2/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/LDPred2/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

DBSLMM

# Set required variables
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

###
# 1KG ref
###
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 5G -p brc,shared -J DBSLMM /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_DBSLMM/Scaled_polygenic_scorer_DBSLMM.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${Geno_1KG_dir}/Score_files_for_polygenic/DBSLMM/${gwas}/1KGPhase3.w_hm3.${gwas}.dbslmm.GW.txt \
  --ref_scale ${Geno_1KG_dir}/Score_files_for_polygenic/DBSLMM/${gwas}/1KGPhase3.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${Geno_1KG_dir}/freq_files/EUR/1KGPhase3.w_hm3.EUR.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/1KG_ref/DBSLMM/${gwas}/TEDS.w_hm3.${gwas}.EUR
done

###
# UKB ref
###
for gwas in $(echo HEIG03 EDUC03 ADHD04 BODY11);do
sbatch -n 1 --mem 5G -p brc,shared -J DBSLMM /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Scaled_polygenic_scorer_DBSLMM/Scaled_polygenic_scorer_DBSLMM.R \
  --target_plink_chr ${TEDS_output_dir}/Genotype/Harmonised/TEDS.w_hm3.QCd.AllSNP.chr \
    --target_keep ${TEDS_output_dir}/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
  --ref_score ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/DBSLMM/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.dbslmm.GW.txt \
  --ref_scale ${UKBB_output}/UKBB_ref/Score_files_for_polygenic/DBSLMM/${gwas}/UKBB.noPheno.EUR.10K.w_hm3.${gwas}.EUR.scale \
  --ref_freq_chr ${UKBB_output}/UKBB_ref/genotype/UKBB.noPheno.EUR.10K.chr \
  --plink ${plink1_9} \
  --pheno_name ${gwas} \
  --output ${TEDS_output_dir}/prs_comparison/UKBB_ref/DBSLMM/${gwas}/TEDS.w_hm3.${gwas}.EUR
done


3.6 Estimating predictive ability

Models containing a single predictor were derived using generalised linear model (GLM). Models containing multiple predictors were derived using elastic-net regularisation to reduce the likelihood of overfitting and account for multicollinearity when modelling highly correlated predictors. 10-fold cross validation was performed using 80% of individuals to identify optimal parameters, with subsequent test-set validation in the remaining 20% of individuals to estimate the predictive utility among individuals not included in the parameter selection process.

First compare the three pT+clump approaches using just using the 1KG reference. Then compare the pT+clump (sparse) and other PRS methods in a range of scenarios. I am seperating these analysese as the former is computationally intensive due to the many thresholds of PRSice.

Model building and evaluation was performed using an Rscript called Model_builder_V2.R (more information here).


3.6.1 UK Biobank

pT + clump comparison

##############################
# Evaluating predictive utility of pT + clump PRSs across multiple pTs individually and in combination
##############################
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Make required directories
for pheno_i in $(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer);do
mkdir -p /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs
done

# Create a file listing the predictors files
pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs-dense.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_dense/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs_nonnested.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/pt_clump_nonnested/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.profiles
EOF

done

# Derive and evaluate models
pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)
prev=$(echo 0.15 NA NA NA 0.05 0.03 0.013 0.00164 0.005 0.125 0.125)

# pT + clump (sparse)
for i in $(seq 1 11);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
    --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs \
    --n_core 2 \
    --compare_predictors F \
    --assoc T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs.predictor_groups
done

# pT + clump (dense)
for i in $(seq 1 11);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 50G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
    --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs-dense \
    --n_core 2 \
    --assoc F \
    --compare_predictors T \
    --eval_only T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs-dense.predictor_groups
done

# pT + clump (non-nested)
for i in $(seq 1 11);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
    --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs_nonnested \
    --n_core 2 \
    --compare_predictors F \
    --assoc T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs_nonnested.predictor_groups
done

SBayesR approaches

SBayesR is performing poorly or some outcomes. I have contacted the authors of SBayesR for further advice. SBayesR seems sensitive to the assumption that each variant effect is estimated in the same sample. To fulfill this assumption authors suggest removing variants that deviate substantially from the sample size median. I have already done this but some GWAS did not have sample size information available and in two cases SBayesR did not perform well even after sample size truncation. Here, the authors suggest imputing sample size based on the SE and MAF of variants and resticting the GWAS to variants with a P<0.4. I also run the analysis using the SBayesR analysis using the GCTB-released LD reference to ensure this isn’t affecting the results.

################################
# Evaluate use of SBayesR PRS
################################
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Create a file listing the predictors files
pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)

for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')

# 1KG ref
cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_P4/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTB_203/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTB_203_robust/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

# GCTB ref
cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_P4.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_P4/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_GCTB_203.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_GCTB_203/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_GCTB_203_robust/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

# UKB ref
cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}_P4/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}_GCTB_203/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
${UKBB_output}/PRS_for_comparison/UKBB_ref/SBayesR/${gwas_i}_GCTB_203_robust/UKBB.subset.w_hm3.${gwas_i}.SBayesR_profiles
EOF

done

pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)
prev=$(echo 0.15 NA NA NA 0.05 0.03 0.013 0.00164 0.005 0.125 0.125)

# Run with 1KG
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs_SBayesR \
  --n_core 2 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups
done

# Run with 1KG and P4 threshold
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_P4.EUR-PRSs_SBayesR \
  --n_core 2 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups
done

# Run with 1KG and GCTB v2.03
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR \
  --n_core 2 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups
done

# Run with 1KG and GCTB v2.03 with forced robust parameterisation
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR \
  --n_core 1 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups
done

# Run with GCTB ref
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref.EUR-PRSs_SBayesR \
  --n_core 2 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref.EUR-PRSs_SBayesR.predictor_groups
done

# Run with GCTB ref with P4 threshold
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_P4.EUR-PRSs_SBayesR \
  --n_core 2 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_P4.EUR-PRSs_SBayesR.predictor_groups
done

# Run with GCTB ref and GCTB v2.03
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_GCTB_203.EUR-PRSs_SBayesR \
  --n_core 2 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_GCTB_203.EUR-PRSs_SBayesR.predictor_groups
done

# Run with GCTB ref and GCTB v2.03 and forced robust
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR \
  --n_core 1 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups
done

# Run with UKB reference
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs_SBayesR \
  --n_core 1 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups
done

# Run with UKB reference with P4 thresh
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_P4.EUR-PRSs_SBayesR \
  --n_core 1 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups
done

# Run with UKB reference with GCTB v2.03
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR \
  --n_core 1 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups
done

# Run with UKB reference with GCTB v2.03 with robust parameterisation
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
pheno_file_i=$(echo ${pheno_file} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR \
  --n_core 1 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups
done

Tabulate SBayesR heritability and convergence info for SBayesR

####
# Create a table comparing SBayesR analyses across LD references 
####

library(data.table)

gwas<-c('DEPR06','COLL01','BODY04','HEIG03','DIAB05','COAD01','CROH01','SCLE03','RHEU02','EDUC03','ADHD04','BODY11','PRCA01','BRCA01')

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

#Processing<-c('','_P4')
#Processing_name<-c('Original','P<0.4')

Processing<-c('','_P4','_GCTB_203','_GCTB_203_robust')
Processing_name<-c('Original','P<0.4','v2.03','v2.03 robust')

GCTB_hsq_all<-NULL
for(process in 1:length(Processing)){
  for(i in 1:length(gwas)){
    GCTB_log<-read.table(paste0(Geno_1KG_dir,'/Score_files_for_polygenic/SBayesR/', gwas[i],Processing[process],'/1KGPhase3.w_hm3.',gwas[i],'.log'), sep='&')
  
    if(sum(grepl('Per variant N is not pres', GCTB_log$V1)) > 0 ){
        perVar<-F
    } else {
        perVar<-T
    }

    if(sum(grepl('No results for chromosomes', GCTB_log$V1)) > 0 ){
        Complete<-F
    } else {
        Complete<-T
    }
  
    hsq<-GCTB_log$V1[grepl('SNP-heritability estimate is ', GCTB_log$V1)]
    hsq<-gsub('\\.$','',gsub('SNP-heritability estimate is ','',hsq))
    hsq_est<-as.numeric(as.character(gsub(' .*','',hsq)))
    hsq_se<-as.numeric(as.character(gsub("\\)",'',gsub(".*\\(SD=",'',hsq))))
    
    tmp<-data.frame( Ref='1KG',
                     Process=Processing_name[process],
                     GWAS=gwas[i],
                     perVar=perVar,
                     Complete=Complete,
                     SBayesR_H2=paste0(round(hsq_est,3)," (SE=",round(hsq_se,3),")"))
                     
    GCTB_hsq_all<-rbind(GCTB_hsq_all, tmp)
  }

  GCTB_N_tab_UKB<-NULL
  for(i in 1:length(gwas)){
    GCTB_log<-read.table(paste0(UKBB_output,'/UKBB_ref/Score_files_for_polygenic/SBayesR/', gwas[i],Processing[process],'/UKBB.noPheno.EUR.10K.w_hm3.',gwas[i],'.log'), sep='&')
  
    if(sum(grepl('Per variant N is not pres', GCTB_log$V1)) > 0 ){
        perVar<-F
    } else {
        perVar<-T
    }
  
    if(sum(grepl('No results for chromosomes', GCTB_log$V1)) > 0 ){
        Complete<-F
    } else {
        Complete<-T
    }

    hsq<-GCTB_log$V1[grepl('SNP-heritability estimate is ', GCTB_log$V1)]
    hsq<-gsub('\\.$','',gsub('SNP-heritability estimate is ','',hsq))
    hsq_est<-as.numeric(as.character(gsub(' .*','',hsq)))
    hsq_se<-as.numeric(as.character(gsub("\\)",'',gsub(".*\\(SD=",'',hsq))))
    
    tmp<-data.frame( Ref='UKB',
                     Process=Processing_name[process],
                     GWAS=gwas[i],
                     perVar=perVar,
                     Complete=Complete,
                     SBayesR_H2=paste0(round(hsq_est,3)," (SE=",round(hsq_se,3),")"))
                     
    GCTB_hsq_all<-rbind(GCTB_hsq_all, tmp)  
 }

  GCTB_N_tab_GCTB<-NULL
  for(i in 1:length(gwas)){
    GCTB_log<-read.table(paste0(Geno_1KG_dir,'/Score_files_for_polygenic/SBayesR/', gwas[i],'_GCTBref',Processing[process],'/1KGPhase3.w_hm3.',gwas[i],'.log'), sep='&')
  
    if(sum(grepl('Per variant N is not pres', GCTB_log$V1)) > 0 ){
        perVar<-F
    } else {
        perVar<-T
    }
  
    if(sum(grepl('No results for chromosomes', GCTB_log$V1)) > 0 ){
        Complete<-F
    } else {
        Complete<-T
    }

    hsq<-GCTB_log$V1[grepl('SNP-heritability estimate is ', GCTB_log$V1)]
    hsq<-gsub('\\.$','',gsub('SNP-heritability estimate is ','',hsq))
    hsq_est<-as.numeric(as.character(gsub(' .*','',hsq)))
    hsq_se<-as.numeric(as.character(gsub("\\)",'',gsub(".*\\(SD=",'',hsq))))
    
    tmp<-data.frame( Ref='GCTB',
                     Process=Processing_name[process],
                     GWAS=gwas[i],
                     perVar=perVar,
                     Complete=Complete,
                     SBayesR_H2=paste0(round(hsq_est,3)," (SE=",round(hsq_se,3),")"))
                     
    GCTB_hsq_all<-rbind(GCTB_hsq_all, tmp)  
  }
}

GCTB_hsq_all$SBayesR_H2_est<-as.numeric(gsub(' .*','',GCTB_hsq_all$SBayesR_H2))
GCTB_hsq_all$SBayesR_H2_se<-as.numeric(gsub("\\)",'',gsub(".*\\(SE=",'',GCTB_hsq_all$SBayesR_H2)))
GCTB_hsq_all$SBayesR_H2<-NULL

GCTB_hsq_all$Converge<-F
GCTB_hsq_all$Converge[GCTB_hsq_all$SBayesR_H2_est < 1.2 & GCTB_hsq_all$Complete == T]<-T

GCTB_hsq_all_use<-NULL
for(i in 1:length(gwas)){
  for(k in c('1KG','UKB','GCTB')){
    GCTB_hsq_all_i_k<-GCTB_hsq_all[GCTB_hsq_all$GWAS == gwas[i] & GCTB_hsq_all$Ref == k,]
    GCTB_hsq_all_i_k$Use<-F
    for(j in 1:length(Processing)){
      if(GCTB_hsq_all_i_k$Converge[j] == T){
        GCTB_hsq_all_i_k$Use[j]<-T
        break()
      }
    }
    GCTB_hsq_all_use<-rbind(GCTB_hsq_all_use, GCTB_hsq_all_i_k)
  }
}

write.csv(GCTB_hsq_all_use, '/users/k1806347/brc_scratch/Analyses/PRS_comparison/SBayesR_H2_comp.csv', row.names=F, quote=F)

# Note. there are several GWAS that do not converge even with P<0.4.
# Estimates of h2 look more reasonable for the robust version of GCTB.

Show SBayesR heritability and N info

SBayesR heritability and N info
Ref Process GWAS perVar Complete SBayesR_H2_est SBayesR_H2_se Converge Use
1KG Original DEPR06 TRUE TRUE 0.035 0.002 TRUE TRUE
1KG P<0.4 DEPR06 TRUE TRUE 0.092 0.003 TRUE FALSE
1KG v2.03 DEPR06 TRUE TRUE 0.035 0.002 TRUE FALSE
1KG v2.03 robust DEPR06 TRUE TRUE 0.043 0.003 TRUE FALSE
UKB Original DEPR06 TRUE TRUE 0.057 0.002 TRUE TRUE
UKB P<0.4 DEPR06 TRUE TRUE 0.138 0.003 TRUE FALSE
UKB v2.03 DEPR06 TRUE TRUE 0.057 0.002 TRUE FALSE
UKB v2.03 robust DEPR06 TRUE TRUE 0.057 0.002 TRUE FALSE
GCTB Original DEPR06 TRUE TRUE 0.058 0.002 TRUE TRUE
GCTB P<0.4 DEPR06 TRUE TRUE 0.140 0.003 TRUE FALSE
GCTB v2.03 DEPR06 TRUE TRUE 0.059 0.002 TRUE FALSE
GCTB v2.03 robust DEPR06 TRUE TRUE 0.058 0.002 TRUE FALSE
1KG Original COLL01 FALSE TRUE 0.113 0.007 TRUE TRUE
1KG P<0.4 COLL01 FALSE TRUE 0.343 0.010 TRUE FALSE
1KG v2.03 COLL01 FALSE TRUE 0.115 0.007 TRUE FALSE
1KG v2.03 robust COLL01 FALSE TRUE 0.112 0.031 TRUE FALSE
UKB Original COLL01 FALSE TRUE 0.162 0.007 TRUE TRUE
UKB P<0.4 COLL01 FALSE TRUE 0.504 0.013 TRUE FALSE
UKB v2.03 COLL01 FALSE TRUE 0.165 0.008 TRUE FALSE
UKB v2.03 robust COLL01 FALSE TRUE 0.141 0.006 TRUE FALSE
GCTB Original COLL01 FALSE TRUE 0.168 0.007 TRUE TRUE
GCTB P<0.4 COLL01 FALSE TRUE 0.531 0.014 TRUE FALSE
GCTB v2.03 COLL01 FALSE TRUE 0.171 0.007 TRUE FALSE
GCTB v2.03 robust COLL01 FALSE TRUE 0.146 0.007 TRUE FALSE
1KG Original BODY04 TRUE TRUE 0.248 0.059 TRUE TRUE
1KG P<0.4 BODY04 TRUE TRUE 0.192 0.016 TRUE FALSE
1KG v2.03 BODY04 TRUE TRUE 0.255 0.064 TRUE FALSE
1KG v2.03 robust BODY04 TRUE TRUE 0.048 0.003 TRUE FALSE
UKB Original BODY04 TRUE TRUE 1.397 0.680 FALSE FALSE
UKB P<0.4 BODY04 TRUE TRUE 1.048 0.420 TRUE TRUE
UKB v2.03 BODY04 TRUE TRUE 1.399 0.680 FALSE FALSE
UKB v2.03 robust BODY04 TRUE TRUE 0.061 0.002 TRUE FALSE
GCTB Original BODY04 TRUE TRUE 0.920 0.430 TRUE TRUE
GCTB P<0.4 BODY04 TRUE TRUE 0.701 0.265 TRUE FALSE
GCTB v2.03 BODY04 TRUE TRUE 0.957 0.461 TRUE FALSE
GCTB v2.03 robust BODY04 TRUE TRUE 0.059 0.002 TRUE FALSE
1KG Original HEIG03 TRUE TRUE 0.718 0.109 TRUE TRUE
1KG P<0.4 HEIG03 TRUE TRUE 0.560 0.057 TRUE FALSE
1KG v2.03 HEIG03 TRUE TRUE 0.719 0.110 TRUE FALSE
1KG v2.03 robust HEIG03 TRUE TRUE 0.251 0.005 TRUE FALSE
UKB Original HEIG03 TRUE TRUE 3.876 1.436 FALSE FALSE
UKB P<0.4 HEIG03 TRUE TRUE 3.163 1.174 FALSE FALSE
UKB v2.03 HEIG03 TRUE TRUE 3.877 1.437 FALSE FALSE
UKB v2.03 robust HEIG03 TRUE TRUE 0.433 0.004 TRUE TRUE
GCTB Original HEIG03 TRUE FALSE 2.806 1.142 FALSE FALSE
GCTB P<0.4 HEIG03 TRUE FALSE 2.424 0.887 FALSE FALSE
GCTB v2.03 HEIG03 TRUE TRUE 2.958 1.157 FALSE FALSE
GCTB v2.03 robust HEIG03 TRUE TRUE 0.440 0.004 TRUE TRUE
1KG Original DIAB05 TRUE TRUE 0.065 0.005 TRUE TRUE
1KG P<0.4 DIAB05 TRUE TRUE 0.225 0.007 TRUE FALSE
1KG v2.03 DIAB05 TRUE TRUE 0.066 0.006 TRUE FALSE
1KG v2.03 robust DIAB05 TRUE TRUE 0.059 0.006 TRUE FALSE
UKB Original DIAB05 TRUE TRUE 0.093 0.005 TRUE TRUE
UKB P<0.4 DIAB05 TRUE TRUE 0.340 0.009 TRUE FALSE
UKB v2.03 DIAB05 TRUE TRUE 0.094 0.005 TRUE FALSE
UKB v2.03 robust DIAB05 TRUE TRUE 0.084 0.005 TRUE FALSE
GCTB Original DIAB05 TRUE TRUE 0.092 0.005 TRUE TRUE
GCTB P<0.4 DIAB05 TRUE TRUE 0.344 0.009 TRUE FALSE
GCTB v2.03 DIAB05 TRUE TRUE 0.093 0.005 TRUE FALSE
GCTB v2.03 robust DIAB05 TRUE TRUE 0.085 0.005 TRUE FALSE
1KG Original COAD01 FALSE TRUE 0.033 0.003 TRUE TRUE
1KG P<0.4 COAD01 FALSE TRUE 0.156 0.005 TRUE FALSE
1KG v2.03 COAD01 FALSE TRUE 0.036 0.003 TRUE FALSE
1KG v2.03 robust COAD01 FALSE TRUE 0.035 0.004 TRUE FALSE
UKB Original COAD01 FALSE TRUE 0.077 0.019 TRUE TRUE
UKB P<0.4 COAD01 FALSE TRUE 0.247 0.020 TRUE FALSE
UKB v2.03 COAD01 FALSE TRUE 0.078 0.019 TRUE FALSE
UKB v2.03 robust COAD01 FALSE TRUE 0.043 0.003 TRUE FALSE
GCTB Original COAD01 FALSE TRUE 0.077 0.021 TRUE TRUE
GCTB P<0.4 COAD01 FALSE TRUE 0.232 0.007 TRUE FALSE
GCTB v2.03 COAD01 FALSE TRUE 0.072 0.016 TRUE FALSE
GCTB v2.03 robust COAD01 FALSE TRUE 0.042 0.003 TRUE FALSE
1KG Original CROH01 FALSE TRUE 0.774 0.246 TRUE TRUE
1KG P<0.4 CROH01 FALSE TRUE 1.468 0.047 FALSE FALSE
1KG v2.03 CROH01 FALSE TRUE 0.905 0.301 TRUE FALSE
1KG v2.03 robust CROH01 FALSE TRUE 0.389 0.042 TRUE FALSE
UKB Original CROH01 FALSE FALSE 0.640 0.141 FALSE FALSE
UKB P<0.4 CROH01 FALSE TRUE 2.073 0.058 FALSE FALSE
UKB v2.03 CROH01 FALSE TRUE 0.589 0.056 TRUE TRUE
UKB v2.03 robust CROH01 FALSE TRUE 0.476 0.031 TRUE FALSE
GCTB Original CROH01 FALSE FALSE 0.835 0.120 FALSE FALSE
GCTB P<0.4 CROH01 FALSE TRUE 2.120 0.057 FALSE FALSE
GCTB v2.03 CROH01 FALSE TRUE 0.933 0.164 TRUE TRUE
GCTB v2.03 robust CROH01 FALSE TRUE 0.485 0.027 TRUE FALSE
1KG Original SCLE03 FALSE TRUE 0.689 0.077 TRUE TRUE
1KG P<0.4 SCLE03 FALSE TRUE 1.345 0.051 FALSE FALSE
1KG v2.03 SCLE03 FALSE TRUE 0.713 0.085 TRUE FALSE
1KG v2.03 robust SCLE03 FALSE TRUE 0.239 0.024 TRUE FALSE
UKB Original SCLE03 FALSE FALSE 0.741 0.094 FALSE FALSE
UKB P<0.4 SCLE03 FALSE FALSE 1.784 0.049 FALSE FALSE
UKB v2.03 SCLE03 FALSE TRUE 0.742 0.092 TRUE TRUE
UKB v2.03 robust SCLE03 FALSE TRUE 0.303 0.021 TRUE FALSE
GCTB Original SCLE03 FALSE FALSE 0.767 0.126 FALSE FALSE
GCTB P<0.4 SCLE03 FALSE FALSE 1.845 0.051 FALSE FALSE
GCTB v2.03 SCLE03 FALSE TRUE 0.697 0.080 TRUE TRUE
GCTB v2.03 robust SCLE03 FALSE TRUE 0.289 0.022 TRUE FALSE
1KG Original RHEU02 FALSE TRUE 0.244 0.011 TRUE TRUE
1KG P<0.4 RHEU02 FALSE TRUE 0.536 0.018 TRUE FALSE
1KG v2.03 RHEU02 FALSE TRUE 0.244 0.011 TRUE FALSE
1KG v2.03 robust RHEU02 FALSE TRUE 0.226 0.015 TRUE FALSE
UKB Original RHEU02 FALSE TRUE 0.358 0.021 TRUE TRUE
UKB P<0.4 RHEU02 FALSE TRUE 0.778 0.022 TRUE FALSE
UKB v2.03 RHEU02 FALSE TRUE 0.365 0.033 TRUE FALSE
UKB v2.03 robust RHEU02 FALSE TRUE 0.352 0.016 TRUE FALSE
GCTB Original RHEU02 FALSE TRUE 0.358 0.012 TRUE TRUE
GCTB P<0.4 RHEU02 FALSE TRUE 0.787 0.022 TRUE FALSE
GCTB v2.03 RHEU02 FALSE TRUE 0.360 0.012 TRUE FALSE
GCTB v2.03 robust RHEU02 FALSE TRUE 0.366 0.016 TRUE FALSE
1KG Original EDUC03 FALSE TRUE 0.063 0.002 TRUE TRUE
1KG P<0.4 EDUC03 FALSE TRUE 0.093 0.002 TRUE FALSE
1KG v2.03 EDUC03 FALSE TRUE 0.063 0.002 TRUE FALSE
1KG v2.03 robust EDUC03 FALSE TRUE 0.063 0.002 TRUE FALSE
UKB Original EDUC03 FALSE TRUE 0.106 0.001 TRUE TRUE
UKB P<0.4 EDUC03 FALSE TRUE 0.143 0.002 TRUE FALSE
UKB v2.03 EDUC03 FALSE TRUE 0.106 0.001 TRUE FALSE
UKB v2.03 robust EDUC03 FALSE TRUE 0.106 0.001 TRUE FALSE
GCTB Original EDUC03 FALSE TRUE 0.108 0.001 TRUE TRUE
GCTB P<0.4 EDUC03 FALSE TRUE 0.143 0.002 TRUE FALSE
GCTB v2.03 EDUC03 FALSE TRUE 0.108 0.001 TRUE FALSE
GCTB v2.03 robust EDUC03 FALSE TRUE 0.109 0.001 TRUE FALSE
1KG Original ADHD04 FALSE TRUE 0.254 0.013 TRUE TRUE
1KG P<0.4 ADHD04 FALSE TRUE 0.902 0.027 TRUE FALSE
1KG v2.03 ADHD04 FALSE TRUE 0.260 0.012 TRUE FALSE
1KG v2.03 robust ADHD04 FALSE TRUE 0.313 0.042 TRUE FALSE
UKB Original ADHD04 FALSE TRUE 0.378 0.016 TRUE TRUE
UKB P<0.4 ADHD04 FALSE TRUE 1.274 0.033 FALSE FALSE
UKB v2.03 ADHD04 FALSE TRUE 0.385 0.015 TRUE FALSE
UKB v2.03 robust ADHD04 FALSE TRUE 0.384 0.015 TRUE FALSE
GCTB Original ADHD04 FALSE TRUE 0.390 0.016 TRUE TRUE
GCTB P<0.4 ADHD04 FALSE TRUE 1.295 0.034 FALSE FALSE
GCTB v2.03 ADHD04 FALSE TRUE 0.395 0.016 TRUE FALSE
GCTB v2.03 robust ADHD04 FALSE TRUE 0.390 0.016 TRUE FALSE
1KG Original BODY11 TRUE TRUE 0.123 0.002 TRUE TRUE
1KG P<0.4 BODY11 TRUE TRUE 0.158 0.002 TRUE FALSE
1KG v2.03 BODY11 TRUE TRUE 0.124 0.002 TRUE FALSE
1KG v2.03 robust BODY11 TRUE TRUE 0.123 0.003 TRUE FALSE
UKB Original BODY11 TRUE TRUE 0.213 0.003 TRUE TRUE
UKB P<0.4 BODY11 TRUE TRUE 0.251 0.002 TRUE FALSE
UKB v2.03 BODY11 TRUE TRUE 0.211 0.002 TRUE FALSE
UKB v2.03 robust BODY11 TRUE TRUE 0.211 0.002 TRUE FALSE
GCTB Original BODY11 TRUE TRUE 0.217 0.003 TRUE TRUE
GCTB P<0.4 BODY11 TRUE TRUE 0.253 0.002 TRUE FALSE
GCTB v2.03 BODY11 TRUE TRUE 0.217 0.003 TRUE FALSE
GCTB v2.03 robust BODY11 TRUE TRUE 0.216 0.002 TRUE FALSE
1KG Original PRCA01 FALSE TRUE 0.124 0.004 TRUE TRUE
1KG P<0.4 PRCA01 FALSE TRUE 0.244 0.005 TRUE FALSE
1KG v2.03 PRCA01 FALSE TRUE 0.126 0.004 TRUE FALSE
1KG v2.03 robust PRCA01 FALSE TRUE 0.124 0.005 TRUE FALSE
UKB Original PRCA01 FALSE TRUE 0.241 0.021 TRUE TRUE
UKB P<0.4 PRCA01 FALSE TRUE 0.351 0.007 TRUE FALSE
UKB v2.03 PRCA01 FALSE TRUE 0.242 0.022 TRUE FALSE
UKB v2.03 robust PRCA01 FALSE TRUE 0.161 0.004 TRUE FALSE
GCTB Original PRCA01 FALSE TRUE 0.195 0.020 TRUE TRUE
GCTB P<0.4 PRCA01 FALSE TRUE 0.357 0.007 TRUE FALSE
GCTB v2.03 PRCA01 FALSE TRUE 0.197 0.021 TRUE FALSE
GCTB v2.03 robust PRCA01 FALSE TRUE 0.163 0.005 TRUE FALSE
1KG Original BRCA01 FALSE TRUE 0.107 0.003 TRUE TRUE
1KG P<0.4 BRCA01 FALSE TRUE 0.209 0.004 TRUE FALSE
1KG v2.03 BRCA01 FALSE TRUE 0.107 0.003 TRUE FALSE
1KG v2.03 robust BRCA01 FALSE TRUE 0.106 0.004 TRUE FALSE
UKB Original BRCA01 FALSE TRUE 0.158 0.003 TRUE TRUE
UKB P<0.4 BRCA01 FALSE TRUE 0.304 0.005 TRUE FALSE
UKB v2.03 BRCA01 FALSE TRUE 0.158 0.003 TRUE FALSE
UKB v2.03 robust BRCA01 FALSE TRUE 0.158 0.004 TRUE FALSE
GCTB Original BRCA01 FALSE TRUE 0.160 0.003 TRUE TRUE
GCTB P<0.4 BRCA01 FALSE TRUE 0.308 0.005 TRUE FALSE
GCTB v2.03 BRCA01 FALSE TRUE 0.160 0.003 TRUE FALSE
GCTB v2.03 robust BRCA01 FALSE TRUE 0.160 0.004 TRUE FALSE

Compare all methods

# We need to read in polygenic scores based on a range of parameters, pseudovalidated scores as a seperate group.
# Create a file listing the predictors files
# For SBayesR, use P<0.4 score for those that do not converge.

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

GCTB_hsq_all<-read.csv('/users/k1806347/brc_scratch/Analyses/PRS_comparison/SBayesR_H2_comp.csv')

pheno<-c('Depression','Intelligence','BMI','Height','T2D','CAD','IBD','MultiScler','RheuArth','Breast_Cancer','Prostate_Cancer')
gwas<-c('DEPR06','COLL01','BODY04','HEIG03','DIAB05','COAD01','CROH01','SCLE03','RHEU02','BRCA01','PRCA01')

for(i in 1:length(pheno)){
  for(ref in c('1KG','UKBB')){
    pred_file<-NULL
    
    # pT+clump (sparse)
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/pt_clump/',gwas[i],'/UKBB.subset.w_hm3.',gwas[i],'.profiles'), 
  group='pT+clump'))
    
    # lassosum
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/lassosum/',gwas[i],'/UKBB.subset.w_hm3.',gwas[i],'.lassosum_profiles'), 
  group='lassosum'))
    
    if(ref == '1KG'){
      # PRScs
      pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/PRScs/',gwas[i],'/UKBB.subset.w_hm3.',gwas[i],'.PRScs_profiles'),
    group='PRScs'))
    }       
  
    # SBLUP
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/SBLUP/',gwas[i],'/UKBB.subset.w_hm3.',gwas[i],'.SBLUP_profiles'),
  group='SBLUP'))
  
    # SBayesR
    # Note use Robust implementation
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/SBayesR/',gwas[i],'_GCTB_203_robust/UKBB.subset.w_hm3.',gwas[i],'.SBayesR_profiles'),
  group='SBayesR'))

    # LDPred
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/LDPred/',gwas[i],'/UKBB.subset.w_hm3.',gwas[i],'.LDPred_profiles'),
  group='LDPred'))
    
    # DBSLMM
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/DBSLMM/',gwas[i],'/UKBB.subset.w_hm3.',gwas[i],'.DBSLMM_profiles'),
  group='DBSLMM'))

    # LDPred2
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(UKBB_output,'/PRS_for_comparison/',ref,'_ref/LDPred2/',gwas[i],'/UKBB.subset.w_hm3.',gwas[i],'.LDPred_profiles'),
  group='LDPred2'))
             
    # Write out list of predictors with groups
    if(ref == '1KG'){
      write.table(pred_file, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/UKBB.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'), row.names=F, col.names=T, quote=F)
    } else {
      write.table(pred_file, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/UKBB.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'), row.names=F, col.names=T, quote=F)
    }
  }
}
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Run Model_builder_V2.R
pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)
prev=$(echo 0.15 NA NA NA 0.05 0.03 0.013 0.00164 0.005 0.125 0.125)

# 1KG reference
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 30G -n 3 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp \
  --n_core 3 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp.predictor_groups
done

# UKBB reference
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 30G -n 3 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs.AllMethodComp \
  --n_core 3 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs.AllMethodComp.predictor_groups
done

Compare all methods with PCs regressed

#############
# Regress project PCs from all polygenic scores
#############

library(data.table)

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

pheno<-c('Depression','Intelligence','BMI','Height','T2D','CAD','IBD','MultiScler','RheuArth','Breast_Cancer','Prostate_Cancer')
gwas<-c('DEPR06','COLL01','BODY04','HEIG03','DIAB05','COAD01','CROH01','SCLE03','RHEU02','BRCA01','PRCA01')

# Read in PCs
pcs<-fread(paste0(UKBB_output,'/Projected_PCs/EUR/UKBB.w_hm3.EUR.eigenvec'))
# Extract the first 20PCs
pcs<-pcs[,c('FID','IID',paste0('PC',1:20))]

for(ref in c('1KG')){
  for(i in 1:length(gwas)){
  
    # Read in list of predictors
    if(ref == '1KG'){
      pred_file<-fread(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/UKBB.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'))
    } else {
      pred_file<-fread(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/UKBB.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'))
    }
    
    for(file in 1:dim(pred_file)[1]){
      # Read in predictors
      file_i<-fread(pred_file$predictors[file])
      
      # Merge with PCs
      file_i_pcs<-merge(file_i, pcs, by=c('FID','IID'))
      for(col_i in names(file_i_pcs)[grepl(gwas[i], names(file_i_pcs))]){
        file_i_pcs_col_i<-file_i_pcs[,c(col_i,paste0('PC',1:20)), with=F]
        names(file_i_pcs_col_i)[names(file_i_pcs_col_i) == col_i]<-'y'
        
        # Regress covariates, scale residuals and round to three decimal places
        file_i_pcs[[paste0(col_i,'_resid')]]<-round(as.numeric(scale(resid(lm(as.formula(paste0('y ~ ', paste(paste0('PC', 1:20), collapse=' + '))), data=file_i_pcs_col_i)))),3)
      }
      
      # Extract residual columns
      file_i_resid<-file_i_pcs[,c('FID','IID',names(file_i_pcs)[grepl('_resid',names(file_i_pcs))]), with=F]
      
      # Save the residuals
      output<-gsub(paste0(ref,'_ref'),paste0(ref,'_ref_PCresid'),pred_file$predictors[file])
      tmp<-sub('.*/','',output)
      output_dir<-sub(paste0(tmp,'*.'),'',output)
      system(paste0('mkdir -p ',output_dir))
      
      write.table(file_i_resid, output, col.names=T, row.names=F, quote=F)
    }
    
    # Write out new list of predictors for residuals
    pred_file_resid<-pred_file
    pred_file_resid$predictors<-gsub(paste0(ref,'_ref'),paste0(ref,'_ref_PCresid'),pred_file$predictors)
    
    if(ref == '1KG'){
      write.table(pred_file_resid, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/UKBB.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.PCresid.predictor_groups'), col.names=T, row.names=F, quote=F)
    } else {
      write.table(pred_file_resid, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/UKBB.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.PCresid.predictor_groups'), col.names=T, row.names=F, quote=F)
    }
  }
}
. /users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config

# Run Model_builder_V2.R
pheno=$(echo Depression Intelligence BMI Height T2D CAD IBD MultiScler RheuArth Breast_Cancer Prostate_Cancer)
gwas=$(echo DEPR06 COLL01 BODY04 HEIG03 DIAB05 COAD01 CROH01 SCLE03 RHEU02 BRCA01 PRCA01)
prev=$(echo 0.15 NA NA NA 0.05 0.03 0.013 0.00164 0.005 0.125 0.125)

# 1KG reference
for i in $(seq 1 11);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 30G -n 3 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
  --pheno ${UKBB_output}/Phenotype/PRS_comp_subset/UKBB.${pheno_i}.txt \
  --keep /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam \
  --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp.PCresid \
  --n_core 3 \
  --compare_predictors T \
  --assoc T \
  --outcome_pop_prev ${prev_i} \
  --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/${pheno_i}/Association_withPRSs/UKBB.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp.PCresid.predictor_groups
done


3.6.2 TEDS

pT + clump comparison

##############################
# Evaluating predictive utility of pT + clump PRSs across multiple pTs individually and in combination
##############################

# Make required directories
for pheno_i in $(echo Height21 BMI21 GCSE ADHD);do
mkdir -p /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs
done

# Create a file listing the predictors files
pheno=$(echo Height21 BMI21 GCSE ADHD)
gwas=$(echo HEIG03 BODY11 EDUC03 ADHD04)

for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/pt_clump/${gwas_i}/TEDS.w_hm3.${gwas_i}.EUR.profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs-dense.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/pt_clump_dense/${gwas_i}/TEDS.w_hm3.${gwas_i}.EUR.profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs_nonnested.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/pt_clump_nonnested/${gwas_i}/TEDS.w_hm3.${gwas_i}.EUR.profiles
EOF

done

pheno=$(echo Height21 BMI21 GCSE ADHD)
gwas=$(echo HEIG03 BODY11 EDUC03 ADHD04)
prev=$(echo NA NA NA NA)

# pT+clump (sparse)
for i in $(seq 1 4);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
      --keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs \
    --n_core 2 \
    --compare_predictors T \
    --assoc T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs.predictor_groups
done

# pT+clump (dense)
for i in $(seq 1 4);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 20G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
      --keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs-dense \
    --n_core 2 \
    --assoc T \
    --compare_predictors T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs-dense.predictor_groups
done

# pT+clump (non-nested)
for i in $(seq 1 4);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
      --keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs_nonnested \
    --n_core 2 \
    --compare_predictors T \
    --assoc T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs_nonnested.predictor_groups
done

SBayesR comparison

################################
# Evaluate use of multiple PRSs based on different shrinkage parameters, and use of pseudo-validated PRS (PRScs)
################################

# Create a file listing the predictors files
pheno=$(echo Height21 BMI21 GCSE ADHD)
gwas=$(echo HEIG03 BODY11 EDUC03 ADHD04)

for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')

# 1KG
cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}_P4/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}_GCTB_203/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}_GCTB_203_robust/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

# GCTB
cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_P4.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_P4/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_GCTB_203.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_GCTB_203/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/1KG_ref/SBayesR/${gwas_i}_GCTBref_GCTB_203_robust/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

# UKB ref
cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/UKBB_ref/SBayesR/${gwas_i}/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/UKBB_ref/SBayesR/${gwas_i}_P4/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/UKBB_ref/SBayesR/${gwas_i}_GCTB_203/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

cat > /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups <<EOF
predictors 
/users/k1806347/brc_scratch/Data/TEDS/prs_comparison/UKBB_ref/SBayesR/${gwas_i}_GCTB_203_robust/TEDS.w_hm3.${gwas_i}.EUR.SBayesR_profiles
EOF

done

# Derive and evaluate
pheno=$(echo Height21 BMI21 GCSE ADHD)
gwas=$(echo HEIG03 BODY11 EDUC03 ADHD04)
prev=$(echo NA NA NA NA)

####
# 1KG ref
####

for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups
done

# P < 0.4
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_P4.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups
done

# GCTB v2.03
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups
done

# GCTB v2.03 robust
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups
done

####
# GCTB ref
####

# Original
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref.EUR-PRSs_SBayesR.predictor_groups
done

# P<0.4
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_P4.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_P4.EUR-PRSs_SBayesR.predictor_groups
done

# GCTB v2.03
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_GCTB_203.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_GCTB_203.EUR-PRSs_SBayesR.predictor_groups
done

# GCTB v2.03 robust
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups
done

###
# UKBB ref
###

for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs_SBayesR.predictor_groups
done

# P<0.4
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_P4.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_P4.EUR-PRSs_SBayesR.predictor_groups
done

# GCTB v2.03
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_GCTB_203.EUR-PRSs_SBayesR.predictor_groups
done

# GCTB v2.03 robust
for i in $(seq 1 4);do
pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 5G -n 1 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
--pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
--keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
--out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR \
--n_core 1 \
--compare_predictors T \
--assoc T \
--outcome_pop_prev ${prev_i} \
--predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}_GCTB_203_robust.EUR-PRSs_SBayesR.predictor_groups
done

Compare all methods

# We need to read in polygenic scores based on a range of parameters, pseudovalidated scores as a seperate group.
# Create a file listing the predictors files

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

pheno<-c('Height21','BMI21','GCSE','ADHD')
gwas<-c('HEIG03','BODY11','EDUC03','ADHD04')

GCTB_hsq_all<-read.csv('/users/k1806347/brc_scratch/Analyses/PRS_comparison/SBayesR_H2_comp.csv')

Processing<-c('','_P4')
Processing_name<-c('Original','P<0.4')

for(i in 1:length(pheno)){
  for(ref in c('1KG','UKBB')){
    if(ref == '1KG'){
      dat_path<-paste0(TEDS_output_dir,'/prs_comparison/1KG_ref/')
    } else {
      dat_path<-paste0(TEDS_output_dir,'/prs_comparison/UKBB_ref/')
    }
    pred_file<-NULL
    
    # pT+clump (sparse)
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'pt_clump/',gwas[i],'/TEDS.w_hm3.',gwas[i],'.EUR.profiles'), 
  group='pT+clump'))
    
    # lassosum
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'lassosum/',gwas[i],'/TEDS.w_hm3.',gwas[i],'.EUR.lassosum_profiles'), 
  group='lassosum'))
    
    if(ref == '1KG'){
      # PRScs
      pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'PRScs/',gwas[i],'/TEDS.w_hm3.',gwas[i],'.EUR.PRScs_profiles'),
      group='PRScs'))
    }          

    # SBLUP
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'SBLUP/',gwas[i],'/TEDS.w_hm3.',gwas[i],'.EUR.SBLUP_profiles'),
  group='SBLUP'))
  
    # SBayesR
    # Use robust mode
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'SBayesR/',gwas[i],'_GCTB_203_robust/TEDS.w_hm3.',gwas[i],'.EUR.SBayesR_profiles'),
  group='SBayesR'))

    # LDPred
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'LDPred/',gwas[i],'/TEDS.w_hm3.',gwas[i],'.EUR.LDPred_profiles'),
  group='LDPred'))
                
    # DBSLMM
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'DBSLMM/',gwas[i],'/TEDS.w_hm3.',gwas[i],'.EUR.DBSLMM_profiles'),
  group='DBSLMM'))

    # LDPred2
    pred_file<-rbind(pred_file,data.frame( predictors=paste0(dat_path,'LDPred2/',gwas[i],'/TEDS.w_hm3.',gwas[i],'.EUR.LDPred_profiles'),
  group='LDPred2'))

    # Write out list of predictors with groups
    if(ref == '1KG'){
        write.table(pred_file, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/TEDS.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'), row.names=F, col.names=T, quote=F)
    } else {
        write.table(pred_file, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/TEDS.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'), row.names=F, col.names=T, quote=F)
    }
  }
}
# Run Model_builder_V2.R
pheno=$(echo Height21 BMI21 GCSE ADHD)
gwas=$(echo HEIG03 BODY11 EDUC03 ADHD04)
prev=$(echo NA NA NA NA)

# 1KG ref
for i in $(seq 1 4);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
      --keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp \
    --n_core 2 \
    --compare_predictors T \
    --assoc T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp.predictor_groups
done

# UKB ref
for i in $(seq 1 4);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
      --keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs.AllMethodComp \
    --n_core 2 \
    --compare_predictors T \
    --assoc T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.UKBB_ref.${gwas_i}.EUR-PRSs.AllMethodComp.predictor_groups
done

Compare all methods with PCs regressed

#############
# Regress project PCs from all polygenic scores
#############

library(data.table)

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

pheno<-c('Height21','BMI21','GCSE','ADHD')
gwas<-c('HEIG03','BODY11','EDUC03','ADHD04')

# Read in PCs
pcs<-fread(paste0('/users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.eigenvec'))
# Extract the first 20PCs
pcs<-pcs[,c('FID','IID',paste0('PC',1:20))]

for(ref in c('1KG')){
  for(i in 1:length(gwas)){
  
    # Read in list of predictors
    if(ref == '1KG'){
      pred_file<-fread(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/TEDS.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'))
    } else {
      pred_file<-fread(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/TEDS.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.predictor_groups'))
    }
    
    for(file in 1:dim(pred_file)[1]){
      # Read in predictors
      file_i<-fread(pred_file$predictors[file])
      
      # Merge with PCs
      file_i_pcs<-merge(file_i, pcs, by=c('FID','IID'))
      for(col_i in names(file_i_pcs)[grepl(gwas[i], names(file_i_pcs))]){
        file_i_pcs_col_i<-file_i_pcs[,c(col_i,paste0('PC',1:20)), with=F]
        names(file_i_pcs_col_i)[names(file_i_pcs_col_i) == col_i]<-'y'
        
        # Regress covariates, scale residuals and round to three decimal places
        file_i_pcs[[paste0(col_i,'_resid')]]<-round(as.numeric(scale(resid(lm(as.formula(paste0('y ~ ', paste(paste0('PC', 1:20), collapse=' + '))), data=file_i_pcs_col_i)))),3)
      }
      
      # Extract residual columns
      file_i_resid<-file_i_pcs[,c('FID','IID',names(file_i_pcs)[grepl('_resid',names(file_i_pcs))]), with=F]
      
      # Save the residuals
      output<-gsub(paste0(ref,'_ref'),paste0(ref,'_ref_PCresid'),pred_file$predictors[file])
      tmp<-sub('.*/','',output)
      output_dir<-sub(paste0(tmp,'*.'),'',output)
      system(paste0('mkdir -p ',output_dir))
      
      write.table(file_i_resid, output, col.names=T, row.names=F, quote=F)
    }
    
    # Write out new list of predictors for residuals
    pred_file_resid<-pred_file
    pred_file_resid$predictors<-gsub(paste0(ref,'_ref'),paste0(ref,'_ref_PCresid'),pred_file$predictors)
    
    if(ref == '1KG'){
      write.table(pred_file_resid, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/TEDS.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.PCresid.predictor_groups'), col.names=T, row.names=F, quote=F)
    } else {
      write.table(pred_file_resid, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/TEDS.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.PCresid.predictor_groups'), col.names=T, row.names=F, quote=F)
    }
  }
}

# Run Model_builder_V2.R
pheno=$(echo Height21 BMI21 GCSE ADHD)
gwas=$(echo HEIG03 BODY11 EDUC03 ADHD04)
prev=$(echo NA NA NA NA)

# 1KG ref
for i in $(seq 1 4);do
  pheno_i=$(echo ${pheno} | cut -f ${i} -d ' ')
  gwas_i=$(echo ${gwas} | cut -f ${i} -d ' ')
  prev_i=$(echo ${prev} | cut -f ${i} -d ' ')

sbatch --mem 10G -n 2 -p brc,shared /users/k1806347/brc_scratch/Software/Rscript.sh /users/k1806347/brc_scratch/Software/MyGit/GenoPred/Scripts/Model_builder/Model_builder_V2.R \
    --pheno /users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_${pheno_i}.txt \
      --keep /users/k1806347/brc_scratch/Data/TEDS/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep \
    --out /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp.PCresid \
    --n_core 2 \
    --compare_predictors T \
    --assoc T \
    --outcome_pop_prev ${prev_i} \
    --predictors /users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/${pheno_i}/Association_withPRSs/TEDS.w_hm3.${gwas_i}.EUR-PRSs.AllMethodComp.PCresid.predictor_groups
done


3.7 Estimating polygenicity of phenotypes

3.7.1 SBayesR

Show code using SBayesR results

library(data.table)
source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Pipeline_prep.config')

gwas<-c('DEPR06','COLL01','HEIG03','BODY04','DIAB05','COAD01','CROH01','SCLE03','RHEU02','EDUC03','ADHD04','BODY11','PRCA01','BRCA01')
pop_prev<-c(0.15,NA,NA,NA,0.05,0.03,0.013,0.00164,0.005,NA,0.05,NA,0.125,0.125)
samp_prev<-c(0.28,NA,NA,NA,0.168,0.33,0.285,0.36,0.246,NA,0.364,NA,0.564,0.537)

h2l_R2 <- function(k, r2, p) {
  # K baseline disease risk
  # r2 from a linear regression model attributable to genomic profile risk score
  # P proportion of sample that are cases
  # calculates proportion of variance explained on the liability scale
  #from ABC at http://www.complextraitgenomics.com/software/
  #Lee SH, Goddard ME, Wray NR, Visscher PM. (2012) A better coefficient of determination for genetic profile analysis. Genet Epidemiol. 2012 Apr;36(3):214-24.
  x= qnorm(1-k)
  z= dnorm(x)
  i=z/k
  C= k*(1-k)*k*(1-k)/(z^2*p*(1-p))
  theta= i*((p-k)/(1-k))*(i*((p-k)/(1-k))-x)
  h2l_R2 = C*r2 / (1 + C*theta*r2)
}

se_h2l_R2 <- function(k,h2,se, p) {
  # K baseline disease risk
  # r2 from a linear regression model attributable to genomic profile risk score
  # P proportion of sample that are cases
  # calculates proportion of variance explained on the liability scale
  #from ABC at http://www.complextraitgenomics.com/software/
  #Lee SH, Goddard ME, Wray NR, Visscher PM. (2012) A better coefficient of determination for genetic profile analysis. Genet Epidemiol. 2012 Apr;36(3):214-24.

  #SE on the liability (From a Taylor series expansion)
  #var(h2l_r2) = [d(h2l_r2)/d(R2v)]^2*var(R2v) with d being calculus differentiation
  x= qnorm(1-k)
  z= dnorm(x)
  i=z/k
  C= k*(1-k)*k*(1-k)/(z^2*p*(1-p))
  theta= i*((p-k)/(1-k))*(i*((p-k)/(1-k))-x)
  se_h2l_R2 = C*(1-h2*theta)*se
}

res_all<-NULL
for(i in 1:length(gwas)){
  # Read in SBayesR parRes
  res<-fread(paste0(Geno_1KG_dir,'/Score_files_for_polygenic/SBayesR/',gwas[i],'_GCTBref_GCTB_203_robust/GWAS_sumstats_SBayesR.GW.parRes'))
  
  if(is.na(pop_prev[i])){
    res_all<-rbind(res_all, data.frame(GWAS=gwas[i],
                                       hsq_mean=res$Mean[res$Par == 'hsq'],
                                       hsq_sd=res$Mean[res$Par == 'hsq'],
                                       NnzSnp_mean=res$Mean[res$Par == 'NnzSnp'],
                                       NnzSnp_sd=res$SD[res$Par == 'NnzSnp']))
  } else {
    res_all<-rbind(res_all, data.frame(GWAS=gwas[i],
                                       hsq_mean=h2l_R2(k=pop_prev[i], r2=res$Mean[res$Par == 'hsq'], p=samp_prev[i]),
                                       hsq_sd=se_h2l_R2(k=pop_prev[i], h2=res$Mean[res$Par == 'hsq'], se=res$SD[res$Par == 'hsq'], p=samp_prev[i]),
                                       NnzSnp_mean=res$Mean[res$Par == 'NnzSnp'],
                                       NnzSnp_sd=res$SD[res$Par == 'NnzSnp']))

  }
}

# Looks reasonable with robust paramterisation, except for BMI when using Locke et al sumstats.


3.7.2 AVENGEME

3.7.2.1 UK Biobank

Show code using AVENGEME results

gwas<-c('DEPR06','COLL01','HEIG03','BODY04','DIAB05','COAD01','CROH01','SCLE03','RHEU02','PRCA01','BRCA01')
pheno<-c('Depression','Intelligence','Height','BMI','T2D','CAD','IBD', 'MultiScler','RheuArth','Prostate_Cancer','Breast_Cancer')
prev=c(0.15,NA,NA,NA,0.05,0.03,0.013,0.00164,0.005,0.125,0.125)

gwas_desc<-read.csv("/users/k1806347/brc_scratch/Data/GWAS_sumstats/UKBB_phenotype_GWAS_descrip.csv")

library(avengeme)

PRS_res<-list()
nsnp_logs<-list()
for(i in 1:length(gwas)){
  res_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/UKBB.w_hm3.',gwas[i],'.EUR-PRSs.assoc.txt'), header=T, stringsAsFactors=F)
  
  res_i<-res_i[1:dim(res_i)[1]-1,]
  if(sum(grepl('Estimate',names(res_i))) == 1){
      res_i$Z<-res_i$Estimate/res_i$SE
  } else {
      res_i$Z<-res_i$BETA/res_i$SE
  }
  
  PRS_res[[gwas[i]]]<-res_i
  
  nsnp_log<-read.table(paste0('/users/k1806347/brc_scratch/Data/1KG/Phase3/Score_files_for_polygenic/pt_clump/',gwas[i],'/1KGPhase3.w_hm3.',gwas[i],'.NSNP_per_pT'), header=T)
  
  nsnp_logs[[gwas[i]]]<-nsnp_log
}

mod_res_all<-NULL
for(i in 1:length(gwas)){
  if(is.na(prev[i])){
    targ_N<-PRS_res[[gwas[i]]]$N[1]
  
    mod_res<-estimatePolygenicModel(p=PRS_res[[gwas[i]]]$Z, 
                           nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                           n=c(gwas_desc$N[gwas_desc$Code == gwas[i]], targ_N), 
                           pupper = c(0,1e-8,1e-06,1e-04,1e-02,0.1,0.2,0.3,0.4,0.5),
                           binary = c(FALSE, FALSE), 
                           prevalence = c(NA, NA), 
                           sampling = c(NA, NA), 
                           fixvg2pi02 = T,
                           alpha = 0.05)
    
    mod_res_all<-rbind(mod_res_all,data.frame(Phenotype=pheno[i],
                                              GWAS=gwas[i],
                                                                          nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                                              vg_est=mod_res$vg[1],
                                              vg_lowCI=mod_res$vg[2],
                                              vg_highCI=mod_res$vg[3],
                                              pi0_est=mod_res$pi0[1],
                                              pi0_lowCI=mod_res$pi0[2],
                                              pi0_highCI=mod_res$pi0[3]))
    
  } else {
    targ_N<-PRS_res[[gwas[i]]]$N[1]
    targ_N_Ca<-PRS_res[[gwas[i]]]$Ncas[1]
    targ_N_Co<-PRS_res[[gwas[i]]]$Ncon[1]

    mod_res<-estimatePolygenicModel(p=PRS_res[[gwas[i]]]$Z, 
                           nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                           n=c(gwas_desc$N[gwas_desc$Code == gwas[i]], targ_N), 
                           pupper = c(0,1e-8,1e-06,1e-04,1e-02,0.1,0.2,0.3,0.4,0.5),
                           binary = c(T, T), 
                           prevalence = prev[i], 
                           sampling = c(gwas_desc$Ncase[gwas_desc$Code == gwas[i]]/(gwas_desc$Ncase[gwas_desc$Code == gwas[i]]+gwas_desc$Ncontrol[gwas_desc$Code == gwas[i]]), targ_N_Ca/(targ_N_Ca+targ_N_Co)), 
                           fixvg2pi02 = T,
                           alpha = 0.05)
    
    mod_res_all<-rbind(mod_res_all,data.frame(Phenotype=pheno[i],
                                              GWAS=gwas[i],
                                                                          nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                                              vg_est=mod_res$vg[1],
                                              vg_lowCI=mod_res$vg[2],
                                              vg_highCI=mod_res$vg[3],
                                              pi0_est=mod_res$pi0[1],
                                              pi0_lowCI=mod_res$pi0[2],
                                              pi0_highCI=mod_res$pi0[3]))
    
  }
}

# A pi0 of 0.98 divides the phenotype nicely into two groups
mod_res_all$HighPoly<-F
mod_res_all$HighPoly[mod_res_all$pi0_est < 0.96]<-T

# T2D, IBD, MultiScler, RheuArth, Prostate_Cancer, and Breast_Cancer are the low polygenicity outcomes.

write.csv(mod_res_all, '/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/PRS_AVENGME_res.csv', row.names=F)


3.7.2.2 TEDS

Show code using AVENGEME results

prev=c(NA,NA,NA,NA)

pheno<-c('Height21', 'BMI21', 'GCSE', 'ADHD')
gwas<-c('HEIG03', 'BODY11', 'EDUC03', 'ADHD04')

gwas_desc<-read.csv("/users/k1806347/brc_scratch/Data/GWAS_sumstats/TEDS_phenotype_GWAS_descrip.csv")

library(avengeme)

PRS_res<-list()
nsnp_logs<-list()
for(i in 1:length(gwas)){
  res_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/TEDS.w_hm3.',gwas[i],'.EUR-PRSs.assoc.txt'), header=T, stringsAsFactors=F)
  
  res_i<-res_i[1:dim(res_i)[1]-1,]
  if(sum(grepl('Estimate',names(res_i))) == 1){
      res_i$Z<-res_i$Estimate/res_i$SE
  } else {
      res_i$Z<-res_i$BETA/res_i$SE
  }
  
  PRS_res[[gwas[i]]]<-res_i
  
  nsnp_log<-read.table(paste0('/users/k1806347/brc_scratch/Data/1KG/Phase3/Score_files_for_polygenic/pt_clump/',gwas[i],'/1KGPhase3.w_hm3.',gwas[i],'.NSNP_per_pT'), header=T)
  
  nsnp_logs[[gwas[i]]]<-nsnp_log
}

mod_res_all<-NULL
for(i in 1:length(gwas)){
  if(is.na(prev[i])){
    targ_N<-PRS_res[[gwas[i]]]$N[1]
  
    mod_res<-estimatePolygenicModel(p=PRS_res[[gwas[i]]]$Z, 
                           nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                           n=c(gwas_desc$N[gwas_desc$Code == gwas[i]], targ_N), 
                           pupper = c(0,1e-8,1e-06,1e-04,1e-02,0.1,0.2,0.3,0.4,0.5),
                           binary = c(FALSE, FALSE), 
                           prevalence = c(NA, NA), 
                           sampling = c(NA, NA), 
                           fixvg2pi02 = T,
                           alpha = 0.05)
    
    mod_res_all<-rbind(mod_res_all,data.frame(Phenotype=pheno[i],
                                              GWAS=gwas[i],
                                                                          nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                                              vg_est=mod_res$vg[1],
                                              vg_lowCI=mod_res$vg[2],
                                              vg_highCI=mod_res$vg[3],
                                              pi0_est=mod_res$pi0[1],
                                              pi0_lowCI=mod_res$pi0[2],
                                              pi0_highCI=mod_res$pi0[3]))
    
  } else {
    targ_N<-PRS_res[[gwas[i]]]$N[1]
    targ_N_Ca<-PRS_res[[gwas[i]]]$Ncas[1]
    targ_N_Co<-PRS_res[[gwas[i]]]$Ncon[1]

    mod_res<-estimatePolygenicModel(p=PRS_res[[gwas[i]]]$Z, 
                           nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                           n=c(gwas_desc$N[gwas_desc$Code == gwas[i]], targ_N), 
                           pupper = c(0,1e-8,1e-06,1e-04,1e-02,0.1,0.2,0.3,0.4,0.5),
                           binary = c(T, T), 
                           prevalence = prev[i], 
                           sampling = c(gwas_desc$Ncase[gwas_desc$Code == gwas[i]]/(gwas_desc$Ncase[gwas_desc$Code == gwas[i]]+gwas_desc$Ncontrol[gwas_desc$Code == gwas[i]]), targ_N_Ca/(targ_N_Ca+targ_N_Co)), 
                           fixvg2pi02 = T,
                           alpha = 0.05)
    
    mod_res_all<-rbind(mod_res_all,data.frame(Phenotype=pheno[i],
                                              GWAS=gwas[i],
                                                                          nsnp=nsnp_logs[[gwas[i]]]$NSNP[length(nsnp_logs[[gwas[i]]]$NSNP)], 
                                              vg_est=mod_res$vg[1],
                                              vg_lowCI=mod_res$vg[2],
                                              vg_highCI=mod_res$vg[3],
                                              pi0_est=mod_res$pi0[1],
                                              pi0_lowCI=mod_res$pi0[2],
                                              pi0_highCI=mod_res$pi0[3]))
    
  }
}

# A pi0 of 0.96 identifies all phenotype in TEDS to high polygenicity, which is accurate.
mod_res_all$HighPoly<-F
mod_res_all$HighPoly[mod_res_all$pi0_est < 0.96]<-T

write.csv(mod_res_all, '/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/PRS_AVENGME_res.csv', row.names=F)


4 Results

Create a sample size table

library(data.table)

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

# Read in a log file for each phenotype and extracr the number of individuals
# UKB
gwas<-c('DEPR06','COLL01','HEIG03','BODY04','DIAB05','COAD01','CROH01','SCLE03','RHEU02','PRCA01','BRCA01')
pheno<-c('Depression','Intelligence','Height','BMI','T2D','CAD','IBD', 'MultiScler','RheuArth','Prostate_Cancer','Breast_Cancer')

keep<-fread('/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/ukb18177_glanville_post_qc_id_list.UpdateIDs.fam')

UKB_N_tab<-NULL
for(i in 1:length(pheno)){
  pheno_i<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',pheno[i],'.txt'))
  names(pheno_i)<-c('FID','IID','pheno')
  pheno_i_keep<-merge(pheno_i, keep, by.x=c('FID','IID'), by.y=c('V1','V2'))
  
  if(length(unique(pheno_i_keep$pheno)) > 2){
      UKB_N_tab<-rbind(UKB_N_tab, data.frame(Phenotype=pheno[i],
                                         N=dim(pheno_i_keep)[1],
                                         Ncase=NA,
                                         Ncont=NA))
  } else {
      UKB_N_tab<-rbind(UKB_N_tab, data.frame(Phenotype=pheno[i],
                                         N=dim(pheno_i_keep)[1],
                                         Ncase=sum(pheno_i_keep$pheno == 0),
                                         Ncont=sum(pheno_i_keep$pheno == 1)))
  }
}

write.csv(UKB_N_tab, '/users/k1806347/brc_scratch/Analyses/PRS_comparison/UKBB_outcomes_for_prediction/UKB_N_table.csv', row.names=F, quote=F)

# TEDS
pheno<-c('Height21', 'BMI21', 'GCSE', 'ADHD')
gwas<-c('HEIG03', 'BODY11', 'EDUC03', 'ADHD04')

keep<-fread(paste0(TEDS_output_dir,'/Projected_PCs/Ancestry_idenitfier/TEDS.w_hm3.AllAncestry.EUR.keep'))

TEDS_N_tab<-NULL
for(i in 1:length(pheno)){
  pheno_i<-fread(paste0('/users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_',pheno[i],'.txt'))
  names(pheno_i)<-c('FID','IID','pheno')
  pheno_i_keep<-merge(pheno_i, keep, by.x=c('FID','IID'), by.y=c('V1','V2'))
  
  TEDS_N_tab<-rbind(TEDS_N_tab, data.frame(Phenotype=pheno[i],
                                         N=dim(pheno_i_keep)[1],
                                         Ncase=NA,
                                         Ncont=NA))
}

write.csv(TEDS_N_tab, '/users/k1806347/brc_scratch/Analyses/PRS_comparison/TEDS_outcomes_for_prediction/TEDS_N_table.csv', row.names=F, quote=F)

Show sample size tables

Sample size of UKB phenotypes after QC
Phenotype N Ncase Ncont
Depression 50000 25000 25000
Intelligence 50000 NA NA
Height 50000 NA NA
BMI 50000 NA NA
T2D 50000 35112 14888
CAD 50000 25000 25000
IBD 50000 46539 3461
MultiScler 50000 48863 1137
RheuArth 50000 46592 3408
Prostate_Cancer 50000 47073 2927
Breast_Cancer 50000 41488 8512
Sample size of TEDS phenotypes after QC
Phenotype N Ncase Ncont
Height21 5455 NA NA
BMI21 5220 NA NA
GCSE 7296 NA NA
ADHD 7880 NA NA

Summarise and plot the results

Files<-c('UKBB','UKBB.UKBB_ref','TEDS','TEDS.UKBB_ref')
Samples<-c('UKBB','UKBB','TEDS','TEDS')
Files_descrip<-c('UKB target with 1KG ref','UKB target with UKB ref','TEDS target with 1KG ref', 'TEDS target with UKB ref')

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

meta_res_eval<-NULL
meta_res_comp<-NULL
meta_res_eval_plots_cross<-list()
meta_res_eval_plots_indep<-list()
meta_res_eval_diff_plots_cross<-list()
meta_res_eval_diff_plots_indep<-list()
meta_res_eval_diff_matrix_cross<-list()
meta_res_eval_diff_matrix_indep<-list()

for(file in 1:length(Files)){
    if(Samples[file] == 'UKBB'){
      pheno<-c('Depression','Intelligence','Height','BMI','T2D','CAD','IBD', 'MultiScler','RheuArth','Prostate_Cancer','Breast_Cancer')
      gwas<-c('DEPR06','COLL01','HEIG03','BODY04','DIAB05','COAD01','CROH01','SCLE03','RHEU02','PRCA01','BRCA01')
    } else {
      pheno<-c('Height21', 'BMI21', 'GCSE', 'ADHD')
      gwas<-c('HEIG03', 'BODY11', 'EDUC03', 'ADHD04')
    }
    
  if(Files[file] == 'UKBB' | Files[file] == 'TEDS'){
    ##################
    # Create a table showing different pT+clump methods
    ##################
    # This is just a quick check that the dense and non-nested approaches improve prediction
    
    res_eval<-NULL
    for(i in 1:length(pheno)){
      pT_clump<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs.pred_eval.txt'), header=T, stringsAsFactors=F)
      pT_clump$Method<-"pT+clump (sparse)"
      Param_tmp<-sort(as.numeric(gsub('e.','e-',gsub('_group','',gsub(paste0(gwas[i],'.'),'',pT_clump$Model)))))
      pT_clump$Param<-as.character(as.numeric(gsub('e.','e-',gsub('_group','',gsub(paste0(gwas[i],'.'),'',pT_clump$Model)))))
      pT_clump$Param[dim(pT_clump)[1]]<-'Multi-PRS'
      pT_clump<-pT_clump[match(c(Param_tmp,'Multi-PRS'), pT_clump$Param),]
      pT_clump$Model<-NULL
      pT_clump$Group<-NA
      pT_clump$Group[pT_clump$CrossVal_R == max(abs(pT_clump$CrossVal_R[pT_clump$Param != 'Multi-PRS']))]<-'10FCVal'
      pT_clump$Group[pT_clump$Param == 'Multi-PRS']<-'Multi-PRS'
      pT_clump<-pT_clump[!is.na(pT_clump$Group),]
    
      pT_clump_nn<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs_nonnested.pred_eval.txt'), header=T, stringsAsFactors=F)
      pT_clump_nn$Method<-"pT+clump (non-nested)"
      pT_clump_nn$Param<-as.character(as.numeric(gsub('e.','e-',gsub('_group','',gsub(paste0(gwas[i],'.'),'',pT_clump_nn$Model)))))
      for(j in (length(pT_clump_nn$Param)-1):1){
        if(j==1){
          pT_clump_nn$Param[j]<-paste0('0 - ',pT_clump_nn$Param[j])
        } else {
          pT_clump_nn$Param[j]<-paste0(pT_clump_nn$Param[j-1],' - ',pT_clump_nn$Param[j])
        }
      }
      pT_clump_nn$Param[dim(pT_clump_nn)[1]]<-'Multi-PRS'
      pT_clump_nn$Model<-NULL
      pT_clump_nn$Group<-NA
      pT_clump_nn$Group[pT_clump_nn$CrossVal_R == max(abs(pT_clump_nn$CrossVal_R[pT_clump_nn$Param != 'Multi-PRS']))]<-'10FCVal'
      pT_clump_nn$Group[pT_clump_nn$Param == 'Multi-PRS']<-'Multi-PRS'
      pT_clump_nn<-pT_clump_nn[!is.na(pT_clump_nn$Group),]
    
      pT_clump_dense<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs-dense.pred_eval.txt'), header=T, stringsAsFactors=F)
      pT_clump_dense$Method<-"pT+clump (dense)"
      Param_tmp<-sort(as.numeric(gsub('e.','e-',gsub('_group','',gsub(paste0(gwas[i],'.'),'',pT_clump_dense$Model)))))
      pT_clump_dense$Param<-as.character(as.numeric(gsub('e.','e-',gsub('_group','',gsub(paste0(gwas[i],'.'),'',pT_clump_dense$Model)))))
      pT_clump_dense$Param[dim(pT_clump_dense)[1]]<-'Multi-PRS'
      pT_clump_dense<-pT_clump_dense[match(c(Param_tmp,'Multi-PRS'), pT_clump_dense$Param),]
      pT_clump_dense$Model<-NULL
      pT_clump_dense$Group<-NA
      pT_clump_dense$Group[pT_clump_dense$CrossVal_R == max(abs(pT_clump_dense$CrossVal_R[pT_clump_dense$Param != 'Multi-PRS']))][1]<-'10FCVal'
      pT_clump_dense$Group[pT_clump_dense$Param == 'Multi-PRS']<-'Multi-PRS'
      pT_clump_dense<-pT_clump_dense[!is.na(pT_clump_dense$Group),]
    
      res_eval_i<-do.call(rbind, list(pT_clump, pT_clump_nn, pT_clump_dense))
      res_eval_i$Phenotype<-pheno[i]
      res_eval_i$CrossVal_OR<-NULL
      res_eval_i$CrossVal_LowCI<-NULL
      res_eval_i$CrossVal_HighCI<-NULL
      res_eval_i$Cross_LiabR2<-NULL
      res_eval_i$Cross_AUC<-NULL
      res_eval_i$CrossVal_Ncas<-NULL
      res_eval_i$CrossVal_Ncon<-NULL
      
      res_eval_i$IndepVal_OR<-NULL
      res_eval_i$IndepVal_LowCI<-NULL
      res_eval_i$IndepVal_HighCI<-NULL
      res_eval_i$Indep_LiabR2<-NULL
      res_eval_i$Indep_AUC<-NULL
      res_eval_i$IndepVal_Ncas<-NULL
      res_eval_i$IndepVal_Ncon<-NULL

      res_eval<-rbind(res_eval, res_eval_i)
    }
    
    res_eval<-res_eval[,c('Phenotype','Method','Group','Param','CrossVal_R','CrossVal_R_SE','CrossVal_pval','IndepVal_R','IndepVal_R_SE','IndepVal_pval')]
    names(res_eval)[3]<-'Model'
    
    write.csv(res_eval, paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',Samples[file],'_pT_clump_eval.csv'), row.names=F, quote=F)
    
  }

  ##################
  # Organise, make tables and figures for per phenotype results
  ##################
  
  res_eval<-NULL
  res_comp<-NULL
  res_eval_plots_cross<-list()
  res_eval_plots_indep<-list()
  res_eval_diff_plots_cross<-list()
  res_eval_diff_plots_indep<-list()
  res_eval_diff_matrix_cross<-list()
  res_eval_diff_matrix_indep<-list()
  for(i in 1:length(pheno)){
    if(grepl('UKBB_ref',Files[file])){
      res_eval_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.pred_eval.txt'), header=T, stringsAsFactors=F)
  
      res_comp_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs.AllMethodComp.pred_comp.txt'), header=T, stringsAsFactors=F)
    } else {
      res_eval_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.pred_eval.txt'), header=T, stringsAsFactors=F)
  
      res_comp_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.pred_comp.txt'), header=T, stringsAsFactors=F)
    }
    
    # Idenitfy model names for 10FCVal, multi-PRS and pseudoval
    selected_models<-NULL
    
    ##
    # pT+clump (sparse)
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_pT<-res_eval_i[grepl('pT.clump.PredFile', res_eval_i$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='pT+clump.10FCVal', Label=
    res_eval_i_per_pT[res_eval_i_per_pT$CrossVal_R == max(res_eval_i_per_pT$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='pT+clump.MultiPRS', Label='pT.clump'))
  
    ##
    # lassosum
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_lassosum<-res_eval_i[grepl('lassosum.PredFile', res_eval_i$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.10FCVal', Label=
    res_eval_i_per_lassosum[res_eval_i_per_lassosum$CrossVal_R == max(res_eval_i_per_lassosum$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.MultiPRS', Label='lassosum'))
  
    # Identify pseudoVal
    lassosum_val<-read.table(paste0('/users/k1806347/brc_scratch/Data/1KG/Phase3/Score_files_for_polygenic/lassosum/',gwas[i],'/1KGPhase3.w_hm3.',gwas[i],'.log'), sep='&')
    lassosum_val_s<-as.numeric(gsub('s = ','',lassosum_val$V1[grepl('s = ',lassosum_val$V1)]))
    lassosum_val_lambda<-as.numeric(gsub('lambda =','',lassosum_val$V1[grepl('lambda =',lassosum_val$V1)]))
    lassosum_val_param<-paste0('s',lassosum_val_s,'.lambda',lassosum_val_lambda)
    lassosum_val_param<-substr(lassosum_val_param, 1, nchar(lassosum_val_param)-1) 
  
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.PseudoVal', Label=res_eval_i[grepl(lassosum_val_param, res_eval_i$Model),]$Model[1]))
    
    ##
    # PRScs
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_PRScs<-res_eval_i[grepl('PRScs.PredFile', res_eval_i$Model),]
    res_eval_i_per_PRScs<-res_eval_i_per_PRScs[!grepl('phiauto', res_eval_i_per_PRScs$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.10FCVal', Label=res_eval_i_per_PRScs[res_eval_i_per_PRScs$CrossVal_R == max(res_eval_i_per_PRScs$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.MultiPRS', Label='PRScs'))
  
    # Identify pseudoval
    res_eval_i_per_PRScs<-res_eval_i[grepl('PRScs.PredFile', res_eval_i$Model),]
    res_eval_i_per_PRScs<-res_eval_i_per_PRScs[grepl('phiauto', res_eval_i_per_PRScs$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.PseudoVal', Label=res_eval_i_per_PRScs[res_eval_i_per_PRScs$CrossVal_R == max(res_eval_i_per_PRScs$CrossVal_R),]$Model[1]))
  
    ##
    # SBLUP
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='SBLUP.Inf', Label='SBLUP'))
    
    ##
    # SBayesR
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='SBayesR.PseudoVal', Label='SBayesR'))
  
    ##
    # LDPred1
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_LDPred<-res_eval_i[grepl('LDPred.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred<-res_eval_i_per_LDPred[!grepl('.LDpred.inf', res_eval_i_per_LDPred$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.10FCVal', Label=res_eval_i_per_LDPred[res_eval_i_per_LDPred$CrossVal_R == max(res_eval_i_per_LDPred$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.MultiPRS', Label='LDPred'))
  
    # Identify pseudoval
    res_eval_i_per_LDPred<-res_eval_i[grepl('LDPred.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred<-res_eval_i_per_LDPred[grepl('.LDpred.inf', res_eval_i_per_LDPred$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.Inf', Label=res_eval_i_per_LDPred[res_eval_i_per_LDPred$CrossVal_R == max(res_eval_i_per_LDPred$CrossVal_R),]$Model[1]))
  
    ##
    # LDPred2
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[!grepl('beta.inf|beta.auto', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.10FCVal', Label=res_eval_i_per_LDPred2[res_eval_i_per_LDPred2$CrossVal_R == max(res_eval_i_per_LDPred2$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.MultiPRS', Label='LDPred2'))
  
    # Identify pseudoval
    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[grepl('beta.inf', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.Inf', Label=res_eval_i_per_LDPred2$Model))

    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[grepl('beta.auto', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.PseudoVal', Label=res_eval_i_per_LDPred2$Model))

    ##
    # DBSLMM
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='DBSLMM.PseudoVal', Label='DBSLMM'))

    ##
    # All methods
    ##
    
    selected_models<-rbind(selected_models,data.frame(Test='All.MultiPRS', Label='All'))

    ###
    # Subset selected models and format
    ###
    
    # Eval
    selected_models$Label_2<-paste0(gsub('_group','',selected_models$Label),'_group')
    res_eval_i_select<-res_eval_i[(res_eval_i$Model %in% selected_models$Label_2),]
    res_eval_i_select<-merge(res_eval_i_select, selected_models[c('Test','Label_2')], by.x='Model',by.y='Label_2')
    res_eval_i_select$Phenotype<-pheno[i]
    if(sum(names(res_eval_i_select) == 'CrossVal_OR') == 0){
      res_eval_i_select$CrossVal_OR<-NA
      res_eval_i_select$CrossVal_LowCI<-NA
      res_eval_i_select$CrossVal_HighCI<-NA
      res_eval_i_select$Cross_LiabR2<-NA
      res_eval_i_select$Cross_AUC<-NA
      res_eval_i_select$CrossVal_Ncas<-NA
      res_eval_i_select$CrossVal_Ncon<-NA
      
      res_eval_i_select$IndepVal_OR<-NA
      res_eval_i_select$IndepVal_LowCI<-NA
      res_eval_i_select$IndepVal_HighCI<-NA
      res_eval_i_select$Indep_LiabR2<-NA
      res_eval_i_select$Indep_AUC<-NA
      res_eval_i_select$IndepVal_Ncas<-NA
      res_eval_i_select$IndepVal_Ncon<-NA
    }
    
    res_eval_i_select<-res_eval_i_select[c('Phenotype','Test',"CrossVal_R","CrossVal_R_SE",'CrossVal_OR','CrossVal_LowCI','CrossVal_HighCI','Cross_LiabR2','Cross_AUC','CrossVal_pval','CrossVal_N','CrossVal_Ncas','CrossVal_Ncon',"IndepVal_R","IndepVal_R_SE",'IndepVal_OR','IndepVal_LowCI','IndepVal_HighCI','Indep_LiabR2','Indep_AUC','IndepVal_pval','IndepVal_N','IndepVal_Ncas','IndepVal_Ncon')]
    
    res_eval<-rbind(res_eval,res_eval_i_select)
    
    # Comp
    selected_models$Label_3<-gsub('_group','',selected_models$Label)
    res_comp_i_select<-res_comp_i[(res_comp_i$Model_1 %in% selected_models$Label_3) & (res_comp_i$Model_2 %in% selected_models$Label_3),]
    res_comp_i_select<-merge(res_comp_i_select, selected_models[c('Test','Label_3')], by.x='Model_1',by.y='Label_3')
    names(res_comp_i_select)[names(res_comp_i_select) == 'Test']<-'Model_1_Test'
    res_comp_i_select<-merge(res_comp_i_select, selected_models[c('Test','Label_3')], by.x='Model_2',by.y='Label_3')
    names(res_comp_i_select)[names(res_comp_i_select) == 'Test']<-'Model_2_Test'
    res_comp_i_select$Label<-NULL
    res_comp_i_select$Phenotype<-pheno[i]
    res_comp_i_select<-res_comp_i_select[c('Phenotype','Model_1_Test','Model_2_Test','Model_1_Cross_R','Model_2_Cross_R','Cross_R_diff','Cross_R_diff_pval','Model_1_Indep_R','Model_2_Indep_R','Indep_R_diff','Indep_R_diff_pval')]
  
    res_comp<-rbind(res_comp,res_comp_i_select)
    
    ###
    # Create plot showing performance of each method
    ###
    
    library(ggplot2)
    library(cowplot)
    
    res_eval_i_select$Method<-gsub('\\..*','',res_eval_i_select$Test)
    res_eval_i_select$Model<-gsub('.*\\.','',res_eval_i_select$Test)
    
    res_eval_i_select$Method<-factor(res_eval_i_select$Method, levels=c('pT+clump','lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
    res_eval_i_select$Model<-factor(res_eval_i_select$Model, levels=c('10FCVal','MultiPRS','PseudoVal','Inf'))
    
    res_eval_plots_cross[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=CrossVal_R, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=CrossVal_R-CrossVal_R_SE, ymax=CrossVal_R+CrossVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$CrossVal_R[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$CrossVal_R[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y') +
                          theme(legend.position="top", legend.title = element_blank(), legend.box="vertical", legend.margin=margin()) +
                          guides(fill=guide_legend(nrow=2))
                                  
    res_eval_plots_indep[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=IndepVal_R, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=IndepVal_R-IndepVal_R_SE, ymax=IndepVal_R+IndepVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$IndepVal_R[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$IndepVal_R[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y') +
                          theme(legend.position="top", legend.title = element_blank(), legend.box="vertical", legend.margin=margin()) +
                          guides(fill=guide_legend(nrow=2))

    ###
    # Create plot showing performance of each method compared to pT+clump
    ###
  
    res_eval_i_select$CrossVal_R_diff<-res_eval_i_select$CrossVal_R-res_eval_i_select$CrossVal_R[res_eval_i_select$Test == "pT+clump.10FCVal"]
    
    res_eval_diff_plots_cross[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=CrossVal_R_diff, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=CrossVal_R_diff-CrossVal_R_SE, ymax=CrossVal_R_diff+CrossVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$CrossVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$CrossVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y') +
                          theme(legend.position="top", legend.title = element_blank(), legend.box="vertical", legend.margin=margin()) +
                          guides(fill=guide_legend(nrow=2))
    
    res_eval_i_select$IndepVal_R_diff<-res_eval_i_select$IndepVal_R-res_eval_i_select$IndepVal_R[res_eval_i_select$Test == "pT+clump.10FCVal"]
                              
    res_eval_diff_plots_indep[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=IndepVal_R_diff, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=IndepVal_R_diff-IndepVal_R_SE, ymax=IndepVal_R_diff+IndepVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$IndepVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$IndepVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y') +
                          theme(legend.position="top", legend.title = element_blank(), legend.box="vertical", legend.margin=margin()) +
                          guides(fill=guide_legend(nrow=2))
  
    ###
    # Create plot showing matrix of differences with significance
    ###
  
    library(reshape2)
    
    res_comp_i_select$Cross_R_diff[res_comp_i_select$Model_1_Test == res_comp_i_select$Model_2_Test]<-NA
    res_comp_i_select$Indep_R_diff[res_comp_i_select$Model_1_Test == res_comp_i_select$Model_2_Test]<-NA

    res_comp_i_select$Cross_R_diff_catagory<-'NA'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff < -0.002]<-'-0.025 - -0.002'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff < -0.025]<-'-0.08 - -0.025'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff < -0.08]<-'< -0.08'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > -0.002 & res_comp_i_select$Cross_R_diff < 0.002]<-'-0.002 - 0.002'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > 0.002]<-'0.002 - 0.025'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > 0.025]<-'0.025 - 0.08'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > 0.08]<-'> 0.08'
    
    res_comp_i_select$Cross_R_diff_catagory<-factor(res_comp_i_select$Cross_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
    res_comp_i_select$Indep_R_diff_catagory<-'NA'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff < -0.002]<-'-0.025 - -0.002'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff < -0.025]<-'-0.08 - -0.025'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff < -0.08]<-'< -0.08'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > -0.002 & res_comp_i_select$Indep_R_diff < 0.002]<-'-0.002 - 0.002'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > 0.002]<-'0.002 - 0.025'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > 0.025]<-'0.025 - 0.08'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > 0.08]<-'> 0.08'
    
    res_comp_i_select$Indep_R_diff_catagory<-factor(res_comp_i_select$Indep_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
    res_comp_i_select$cross_star<-' '
    res_comp_i_select$cross_star[res_comp_i_select$Cross_R_diff_pval < 0.05]<-'*'
    res_comp_i_select$cross_star[res_comp_i_select$Cross_R_diff_pval < 1e-3]<-'**'
    res_comp_i_select$cross_star[res_comp_i_select$Cross_R_diff_pval < 1e-6]<-'***'
  
    res_comp_i_select$indep_star<-' '
    res_comp_i_select$indep_star[res_comp_i_select$Indep_R_diff_pval < 0.05]<-'*'
    res_comp_i_select$indep_star[res_comp_i_select$Indep_R_diff_pval < 1e-3]<-'**'
    res_comp_i_select$indep_star[res_comp_i_select$Indep_R_diff_pval < 1e-6]<-'***'
  
    
    library(RColorBrewer)
    res_eval_diff_matrix_cross[[pheno[i]]]<-ggplot(data = res_comp_i_select, aes(Model_2_Test, Model_1_Test, fill=Cross_R_diff_catagory))+
     geom_tile(color = "white")+
     labs(y='Test', x='Comparison', title=pheno[i], fill='R difference') +
      theme_minimal()+ 
     theme(axis.text.x = element_text(angle = 45, vjust = 1, 
        size = 8, hjust = 1))+
     coord_fixed() +
    geom_text(data=res_comp_i_select, aes(Model_2_Test, Model_1_Test, label = cross_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(res_comp_i_select$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')

    res_eval_diff_matrix_indep[[pheno[i]]]<-ggplot(data = res_comp_i_select, aes(Model_2_Test, Model_1_Test, fill=Indep_R_diff_catagory))+
     geom_tile(color = "white")+
     labs(y='Test', x='Comparison', title=pheno[i], fill='R difference') +
     theme_minimal()+ 
     theme(axis.text.x = element_text(angle = 45, vjust = 1, 
     size = 8, hjust = 1))+
     coord_fixed() +
    geom_text(data=res_comp_i_select, aes(Model_2_Test, Model_1_Test, label = indep_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(res_comp_i_select$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')
  }
  
  write.csv(res_eval, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'.csv'), row.names=F, quote=F)
  
  write.csv(res_comp, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'_diff.csv'), row.names=F, quote=F)
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_CrossVal_',Files[file],'.png'), units='px', res=300, width=2450, height=1000*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_plots_cross, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_IndepVal_',Files[file],'.png'), units='px', res=300, width=2450, height=1000*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_plots_indep, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_pTDiff_CrossVal_',Files[file],'.png'), units='px', res=300, width=2450, height=1000*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_diff_plots_cross, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_pTDiff_IndepVal_',Files[file],'.png'), units='px', res=300, width=2450, height=1000*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_diff_plots_indep, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'_diff_CrossVal.png'), units='px', res=300, width=2450, height=1750*length(res_eval_diff_matrix_cross))
  print(plot_grid(plotlist=res_eval_diff_matrix_cross, ncol = 1))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'_diff_IndepVal.png'), units='px', res=300, width=2450, height=1750*length(res_eval_diff_matrix_cross))
  print(plot_grid(plotlist=res_eval_diff_matrix_indep, ncol = 1))
  dev.off()
  
  ###################
  # Average results across phenotypes, creates tables and figures
  ###################
  
  res_eval$Method<-gsub('\\..*','',res_eval$Test)
  res_eval$Model<-gsub('.*\\.','',res_eval$Test)
  
  res_eval$Phenotype<-factor(res_eval$Phenotype, level=unique(res_eval$Phenotype))
  res_eval$Method<-factor(res_eval$Method, level=c("pT+clump",'lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
  res_eval$Model<-factor(res_eval$Model, level=c('10FCVal','MultiPRS','PseudoVal','Inf'))
  
  res_eval<-res_eval[order(res_eval$Phenotype, res_eval$Method, res_eval$Model),]
  
  library(data.table)
  source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')
  
  if(Samples[file] == 'UKBB'){
    for(pheno_i in 1:length(pheno)){
      if(pheno_i==1){
        pheno_i_dat<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-pheno_i_dat
      } else {
        pheno_i_dat<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-merge(pheno_dat, pheno_i_dat, by=c('FID','IID'), all=T)
      }
    }
  } else {
    for(pheno_i in 1:length(pheno)){
      if(pheno_i==1){
        pheno_i_dat<-fread(paste0('/users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-pheno_i_dat
      } else {
        pheno_i_dat<-fread(paste0('/users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-merge(pheno_dat, pheno_i_dat, by=c('FID','IID'), all=T)
      }
    }
  }
  
  # Calculate corelation between all phenotypes
  cors<-abs(cor(as.matrix(pheno_dat[,-1:-2]), use='p'))
  cors<-cors[unique(res_eval$Phenotype,),unique(res_eval$Phenotype,)]
  cors[is.na(cors)]<-0

  # Run aggregate function
  library(MAd)
  meta_res_eval<-NULL
  for(i in unique(res_eval$Test)){
    res_eval_i<-res_eval[res_eval$Test == i,]
    res_eval_i$Sample<-'Target'
    
    cors_i<-cors[(dimnames(cors)[[1]] %in% res_eval_i$Phenotype),(dimnames(cors)[[1]] %in% res_eval_i$Phenotype)]

    CrossVal_agg_res_eval_i<-agg(id=Sample, es=CrossVal_R, var=CrossVal_R_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_eval_i)
    IndepVal_agg_res_eval_i<-agg(id=Sample, es=IndepVal_R, var=IndepVal_R_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_eval_i)
  
    meta_res_eval<-rbind(meta_res_eval, data.frame(  Test=i,
                                           CrossVal_R=CrossVal_agg_res_eval_i$es[1],
                                           CrossVal_R_SE=sqrt(CrossVal_agg_res_eval_i$var[1]),
                                           IndepVal_R=IndepVal_agg_res_eval_i$es[1],
                                           IndepVal_R_SE=sqrt(IndepVal_agg_res_eval_i$var[1])))
  }
  
  # Calculate difference between methods and p-value using aggregate
  # Truncate difference p-values to stop 0 values
  res_comp$Cross_R_diff_pval[res_comp$Cross_R_diff_pval == 0]<-1e-320
  res_comp$Indep_R_diff_pval[res_comp$Indep_R_diff_pval == 0]<-1e-320
  
  meta_res_diff<-NULL
  for(i in unique(res_eval$Test)){
    for(k in unique(res_eval$Test)){
      meta_res_eval_i<-meta_res_eval[meta_res_eval$Test == i,]
      meta_res_eval_k<-meta_res_eval[meta_res_eval$Test == k,]
  
      res_comp_i_k<-res_comp[res_comp$Model_1_Test == i & res_comp$Model_2_Test == k,]
      
      # Calculate diff SE based on p-value
      for(j in 1:dim(res_comp_i_k)[1]){
        if(res_comp_i_k$Cross_R_diff_pval[j] == 1){
          res_comp_i_k$Cross_R_diff_pval[j]<-1-0.001
        }
        if(res_comp_i_k$Indep_R_diff_pval[j] == 1){
          res_comp_i_k$Indep_R_diff_pval[j]<-1-0.001
        }
      }

      res_comp_i_k$Cross_R_diff_z<-qnorm(res_comp_i_k$Cross_R_diff_pval/2)
      res_comp_i_k$Cross_R_diff_SE<-res_comp_i_k$Cross_R_diff/res_comp_i_k$Cross_R_diff_z
  
      res_comp_i_k$Indep_R_diff_z<-qnorm(res_comp_i_k$Indep_R_diff_pval/2)
      res_comp_i_k$Indep_R_diff_SE<-res_comp_i_k$Indep_R_diff/res_comp_i_k$Indep_R_diff_z
      
      res_comp_i_k$Sample<-'A'
      
      cors_i<-cors[(dimnames(cors)[[1]] %in% res_comp_i_k$Phenotype),(dimnames(cors)[[1]] %in% res_comp_i_k$Phenotype)]

      CrossVal_agg_res_comp_i_k<-agg(id=Sample, es=Cross_R_diff, var=Cross_R_diff_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_comp_i_k)
      
      IndepVal_agg_res_eval_i<-agg(id=Sample, es=Indep_R_diff, var=Indep_R_diff_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_comp_i_k)
    
      meta_res_diff<-rbind(meta_res_diff, data.frame(Test_ref=i,
                                                     Test_targ=k,
                                                     CrossVal_R_diff=CrossVal_agg_res_comp_i_k$es[1],
                                                     CrossVal_R_diff_SE=sqrt(CrossVal_agg_res_comp_i_k$var[1]),
                                                     IndepVal_R_diff=IndepVal_agg_res_eval_i$es[1],
                                                     IndepVal_R_diff_SE=sqrt(IndepVal_agg_res_eval_i$var[1])))
    }
  }
                                           
  meta_res_diff$CrossVal_R_diff_Z<-meta_res_diff$CrossVal_R_diff/meta_res_diff$CrossVal_R_diff_SE
  meta_res_diff$CrossVal_R_diff_P<-2*pnorm(-abs(meta_res_diff$CrossVal_R_diff_Z))              
  meta_res_diff$IndepVal_R_diff_Z<-meta_res_diff$IndepVal_R_diff/meta_res_diff$IndepVal_R_diff_SE
  meta_res_diff$IndepVal_R_diff_P<-2*pnorm(-abs(meta_res_diff$IndepVal_R_diff_Z))              
  meta_res_diff<-meta_res_diff[,c("Test_ref","Test_targ","CrossVal_R_diff","CrossVal_R_diff_Z","CrossVal_R_diff_P","IndepVal_R_diff","IndepVal_R_diff_Z","IndepVal_R_diff_P")]
  
  meta_res_diff$CrossVal_R_diff_Z[meta_res_diff$CrossVal_R_diff == 0]<-0
  meta_res_diff$CrossVal_R_diff_P[meta_res_diff$CrossVal_R_diff == 0]<-1
  meta_res_diff$IndepVal_R_diff_Z[meta_res_diff$IndepVal_R_diff == 0]<-0
  meta_res_diff$IndepVal_R_diff_P[meta_res_diff$IndepVal_R_diff == 0]<-1
  
  # Calculate percentage improvement
  meta_res_diff$CrossVal_R_diff_perc<-NA
  for(i in unique(meta_res_diff$Test_ref)){
    meta_res_diff$CrossVal_R_diff_perc[meta_res_diff$Test_ref == i]<-meta_res_diff$CrossVal_R_diff[meta_res_diff$Test_ref == i]/meta_res_eval$CrossVal_R[meta_res_eval$Test == i]*100
  }
  
  meta_res_diff$IndepVal_R_diff_perc<-NA
  for(i in unique(meta_res_diff$Test_ref)){
    meta_res_diff$IndepVal_R_diff_perc[meta_res_diff$Test_ref == i]<-meta_res_diff$IndepVal_R_diff[meta_res_diff$Test_ref == i]/meta_res_eval$IndepVal_R[meta_res_eval$Test == i]*100
  }
  
  write.csv(meta_res_eval, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'_meta.csv'), row.names=F, quote=F)
  
  meta_res_diff<-meta_res_diff[,c("Test_ref","Test_targ","CrossVal_R_diff",'CrossVal_R_diff_perc',"CrossVal_R_diff_Z","CrossVal_R_diff_P","IndepVal_R_diff",'IndepVal_R_diff_perc',"IndepVal_R_diff_Z","IndepVal_R_diff_P")]    
  
  write.csv(meta_res_diff, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'_diff_meta.csv'), row.names=F, quote=F)
  
  ###
  # Create plot showing performance of each method
  ###
  
    # To avoid unequal groups, insert NA for missing Model/Method pairs
  meta_res_eval$Method<-gsub('\\..*','',meta_res_eval$Test)
  meta_res_eval$Model<-gsub('.*\\.','',meta_res_eval$Test)

  meta_res_eval$Method<-factor(meta_res_eval$Method, levels=c("pT+clump",'lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
  meta_res_eval$Model<-factor(meta_res_eval$Model, levels=c('10FCVal','MultiPRS','PseudoVal','Inf'))

  for(i in unique(meta_res_eval$Method)){
    for(k in unique(meta_res_eval$Model)){
      if(dim(meta_res_eval[meta_res_eval$Method == i & meta_res_eval$Model == k,])[1] > 0){
        next
      } else {
        dud<-data.frame(Test=NA,
                        CrossVal_R=NA,
                        CrossVal_R_SE=NA,
                        IndepVal_R=NA,
                        IndepVal_R_SE=NA,
                        Method=i,
                        Model=k)
        meta_res_eval<-rbind(meta_res_eval,dud)
      }
    }
  }
  
  res_eval<-res_eval[,c('Phenotype','Test','CrossVal_R','IndepVal_R','Method','Model')]
  
  for(i in unique(res_eval$Method)){
    for(k in unique(res_eval$Model)){
      if(dim(res_eval[res_eval$Method == i & res_eval$Model == k,])[1] > 0){
        next
      } else {
        dud<-data.frame(Phenotype=NA,
                        Test=paste0(i,'.',k),
                        CrossVal_R=NA,
                        IndepVal_R=NA,
                        Method=i,
                        Model=k)
        res_eval<-rbind(res_eval,dud)
      }
    }
  }
  
  library(ggplot2)
  library(cowplot)
  
  meta_res_eval_plots_cross[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=CrossVal_R, fill=Model)) +
                        geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                        geom_errorbar(aes(ymin=CrossVal_R-CrossVal_R_SE, ymax=CrossVal_R+CrossVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                        labs(y="Correlation (SE)", x='', title=Files_descrip[file]) +
                        theme_half_open() +
                              theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                              geom_vline(xintercept = 1.5, linetype="dotted") +
                              geom_vline(xintercept = 2.5, linetype="dotted") + 
                              geom_vline(xintercept = 3.5, linetype="dotted") + 
                              geom_vline(xintercept = 4.5, linetype="dotted") + 
                              geom_vline(xintercept = 5.5, linetype="dotted") +
                              geom_vline(xintercept = 6.5, linetype="dotted") +
                              geom_vline(xintercept = 7.5, linetype="dotted") +
                              geom_vline(xintercept = 8.5, linetype="dotted") +
                        background_grid(major = 'y', minor = 'y')

  meta_res_eval_plots_indep[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=IndepVal_R, fill=Model)) +
                        geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                        geom_errorbar(aes(ymin=IndepVal_R-IndepVal_R_SE, ymax=IndepVal_R+IndepVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                        labs(y="Correlation (SE)", x='', title=Files_descrip[file]) +
                        theme_half_open() +
                              theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                              geom_vline(xintercept = 1.5, linetype="dotted") +
                              geom_vline(xintercept = 2.5, linetype="dotted") + 
                              geom_vline(xintercept = 3.5, linetype="dotted") + 
                              geom_vline(xintercept = 4.5, linetype="dotted") + 
                              geom_vline(xintercept = 5.5, linetype="dotted") +
                              geom_vline(xintercept = 6.5, linetype="dotted") +
                              geom_vline(xintercept = 7.5, linetype="dotted") +
                              geom_vline(xintercept = 8.5, linetype="dotted") +
                        background_grid(major = 'y', minor = 'y')
  
  if(Samples[file] == 'UKBB'){
    meta_res_eval_plots_cross[[Files[file]]]<-meta_res_eval_plots_cross[[Files[file]]] + coord_cartesian(ylim=c(0,0.25), clip="on")
    meta_res_eval_plots_indep[[Files[file]]]<-meta_res_eval_plots_indep[[Files[file]]] + coord_cartesian(ylim=c(0,0.25), clip="on")
  } else {
    meta_res_eval_plots_cross[[Files[file]]]<-meta_res_eval_plots_cross[[Files[file]]] + coord_cartesian(ylim=c(0,0.375), clip="on")
    meta_res_eval_plots_indep[[Files[file]]]<-meta_res_eval_plots_indep[[Files[file]]] + coord_cartesian(ylim=c(0,0.375), clip="on")
  }                           

  ###
  # Create plot showing performance of each method compared to pT+clump
  ###
  
    # Calculate differences at the average and phenotype specific level
    meta_res_eval$CrossVal_R_diff<-meta_res_eval$CrossVal_R-meta_res_eval$CrossVal_R[which(meta_res_eval$Test == "pT+clump.10FCVal")]
    
    meta_res_eval$IndepVal_R_diff<-meta_res_eval$IndepVal_R-meta_res_eval$IndepVal_R[which(meta_res_eval$Test == "pT+clump.10FCVal")]
    
    res_eval$CrossVal_R_diff<-NA
    res_eval$IndepVal_R_diff<-NA
    for(i in pheno){
        res_eval$CrossVal_R_diff[which(res_eval$Phenotype == i)]<-res_eval$CrossVal_R[which(res_eval$Phenotype == i)]-res_eval$CrossVal_R[which(res_eval$Test == "pT+clump.10FCVal" & res_eval$Phenotype == i)]
    
        res_eval$IndepVal_R_diff[which(res_eval$Phenotype == i)]<-res_eval$IndepVal_R[which(res_eval$Phenotype == i)]-res_eval$IndepVal_R[which(res_eval$Test == "pT+clump.10FCVal" & res_eval$Phenotype == i)]
    }

    meta_res_eval_diff_plots_cross[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=CrossVal_R_diff, fill=Model)) +
                          geom_point(data=res_eval, mapping=aes(x=Method, y=CrossVal_R_diff, colour=Model), position=position_jitterdodge(jitter.width = 0.4, dodge.width = 0.7), alpha=0.3) +
                        geom_errorbar(aes(ymin=CrossVal_R_diff-CrossVal_R_SE, ymax=CrossVal_R_diff+CrossVal_R_SE), width=0.9, position=position_dodge(width = 0.7)) +
                          geom_point(stat="identity", position=position_dodge(0.7), size=2, shape=23, colour='black') +
                          labs(y="Difference in\nCorrelations (SE)", x='', title=Files_descrip[file]) +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                                  geom_vline(xintercept = 1.5, linetype="dotted") +
                                  geom_vline(xintercept = 2.5, linetype="dotted") + 
                                  geom_vline(xintercept = 3.5, linetype="dotted") + 
                                  geom_vline(xintercept = 4.5, linetype="dotted") + 
                                  geom_vline(xintercept = 5.5, linetype="dotted") +
                                  geom_vline(xintercept = 6.5, linetype="dotted") +
                                  geom_vline(xintercept = 7.5, linetype="dotted") +
                                  geom_vline(xintercept = 8.5, linetype="dotted") +
                          background_grid(major = 'y', minor = 'y') +
                          ylim(c(-0.08,0.12))
                              
    meta_res_eval_diff_plots_indep[[Files[file]]] <- ggplot(meta_res_eval, aes(x=Method, y=IndepVal_R_diff, fill=Model)) +
                          geom_point(data=res_eval, mapping=aes(x=Method, y=IndepVal_R_diff, colour=Model), position=position_jitterdodge(jitter.width = 0.4, dodge.width = 1), alpha=0.3) +
                          geom_errorbar(aes(ymin=IndepVal_R_diff-IndepVal_R_SE, ymax=IndepVal_R_diff+IndepVal_R_SE), width=0.9, position=position_dodge(width = 1)) +
                          geom_point(stat="identity", position=position_dodge(1), size=2, shape=23, colour='black') +
                          labs(y="Difference in\nCorrelations (SE)", x='', title=Files_descrip[file]) +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                                  geom_vline(xintercept = 1.5, linetype="dotted") +
                                  geom_vline(xintercept = 2.5, linetype="dotted") + 
                                  geom_vline(xintercept = 3.5, linetype="dotted") + 
                                  geom_vline(xintercept = 4.5, linetype="dotted") + 
                                  geom_vline(xintercept = 5.5, linetype="dotted") +
                                  geom_vline(xintercept = 6.5, linetype="dotted") +
                                  geom_vline(xintercept = 7.5, linetype="dotted") +
                                  geom_vline(xintercept = 8.5, linetype="dotted") +
                          background_grid(major = 'y', minor = 'y') +
                          ylim(c(-0.08,0.12))

  ###
  # Create plot showing matrix of differences with significance
  ###
  
  library(reshape2)
  
  meta_res_diff$CrossVal_R_diff[meta_res_diff$Test_ref == meta_res_diff$Test_targ]<-NA
  meta_res_diff$IndepVal_R_diff[meta_res_diff$Test_ref == meta_res_diff$Test_targ]<-NA
  
  meta_res_diff$Cross_R_diff_catagory<-'NA'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.002]<-'-0.025 - -0.002'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.025]<-'-0.08 - -0.025'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.08]<-'< -0.08'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > -0.002 & meta_res_diff$CrossVal_R_diff < 0.002]<-'-0.002 - 0.002'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.002]<-'0.002 - 0.025'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.025]<-'0.025 - 0.08'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.08]<-'> 0.08'
  
  meta_res_diff$Cross_R_diff_catagory<-factor(meta_res_diff$Cross_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
  meta_res_diff$Indep_R_diff_catagory<-'NA'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.002]<-'-0.025 - -0.002'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.025]<-'-0.08 - -0.025'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.08]<-'< -0.08'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > -0.002 & meta_res_diff$IndepVal_R_diff < 0.002]<-'-0.002 - 0.002'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.002]<-'0.002 - 0.025'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.025]<-'0.025 - 0.08'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.08]<-'> 0.08'
  
  meta_res_diff$Indep_R_diff_catagory<-factor(meta_res_diff$Indep_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
  meta_res_diff$cross_star<-' '
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 0.05]<-'*'
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 1e-3]<-'**'
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 1e-6]<-'***'
  
  meta_res_diff$indep_star<-' '
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 0.05]<-'*'
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 1e-3]<-'**'
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 1e-6]<-'***'
  
  library(RColorBrewer)
  meta_res_eval_diff_matrix_cross[[Files[file]]]<-ggplot(data = meta_res_diff, aes(Test_targ, Test_ref, fill=Cross_R_diff_catagory))+
   geom_tile(color = "white")+
   labs(y='Test', x='Comparison', title=Files_descrip[file], fill='R difference') +
    theme_minimal()+ 
   theme(axis.text.x = element_text(angle = 45, vjust = 1, 
      size = 8, hjust = 1)) +
   coord_fixed() +
  geom_text(data=meta_res_diff, aes(Test_ref, Test_targ, label = cross_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(meta_res_diff$Cross_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')
  
  meta_res_eval_diff_matrix_indep[[Files[file]]]<-ggplot(data = meta_res_diff, aes(Test_targ, Test_ref, fill=Indep_R_diff_catagory))+
   geom_tile(color = "white")+
   labs(y='Test', x='Comparison', title=Files_descrip[file], fill='R difference') +
    theme_minimal()+ 
   theme(axis.text.x = element_text(angle = 45, vjust = 1, 
      size = 8, hjust = 1))+
   coord_fixed() +
  geom_text(data=meta_res_diff, aes(Test_targ, Test_ref, label = indep_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(meta_res_diff$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')

}

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_CrossVal_meta.png', units='px', res=300, width=3400, height=2000)
plot_grid(plotlist=meta_res_eval_plots_cross, ncol = 2, nrow = 2)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_IndepVal_meta.png', units='px', res=300, width=3400, height=2000)
plot_grid(plotlist=meta_res_eval_plots_indep, ncol = 2, nrow = 2)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_pTDiff_CrossVal_meta.png', units='px', res=300, width=3400, height=2000)
plot_grid(plotlist=meta_res_eval_diff_plots_cross, ncol = 2, nrow = 2)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_pTDiff_IndepVal_meta.png', units='px', res=300, width=3400, height=2000)
plot_grid(plotlist=meta_res_eval_diff_plots_indep, ncol = 2, nrow = 2)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_diff_CrossVal_meta.png', units='px', res=300, width=4000, height=4000)
plot_grid(plotlist=meta_res_eval_diff_matrix_cross, ncol = 2, nrow = 2)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_diff_IndepVal_meta.png', units='px', res=300, width=4000, height=4000)
plot_grid(plotlist=meta_res_eval_diff_matrix_indep, ncol = 2, nrow = 2)
dev.off()

# UKB 1KG ref only
tiff('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_UKB_1KG_IndepVal_meta.tiff', units='px', res=300, width=1750, height=2000, compression = 'lzw')
plot_A<-meta_res_eval_plots_indep[[1]] + 
    labs(title=NULL)
plot_B<-meta_res_eval_diff_plots_indep[[1]] + 
    labs(title=NULL) +
    ylim(c(-0.075,0.075))
plot_grid(plotlist=list(plot_A, plot_B), nrow = 2, labels=c('A','B'))
dev.off()

tiff('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_diff_UKB_1KG_IndepVal_meta.tiff', units='px', res=300, width=2000, height=2000, compression = 'lzw')
meta_res_eval_diff_matrix_indep[[1]] + labs(title=NULL)
dev.off()

Summarise and plot results split by polygenicity

Files<-c('UKBB.HighPoly','UKBB.LowPoly')
Samples<-c('UKBB','UKBB')
Files_descrip<-c('UKB target with 1KG ref:\nHigh polygenicity','UKB target with 1KG ref:\nLow polygenicity')

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

meta_res_eval<-NULL
meta_res_comp<-NULL
meta_res_eval_plots_cross<-list()
meta_res_eval_plots_indep<-list()
meta_res_eval_diff_plots_cross<-list()
meta_res_eval_diff_plots_indep<-list()
meta_res_eval_diff_matrix_cross<-list()
meta_res_eval_diff_matrix_indep<-list()

for(file in 1:length(Files)){
    if(file == 1){
      pheno<-c('Depression','Intelligence','BMI','Height','CAD')
      gwas<-c('DEPR06','COLL01','BODY04','HEIG03','COAD01')
    } else {
      pheno<-c('T2D','IBD','MultiScler','RheuArth','Prostate_Cancer','Breast_Cancer')
      gwas<-c('DIAB05','CROH01','SCLE03','RHEU02','PRCA01','BRCA01')
    }

  ##################
  # Organise, make tables and figures for per phenotype results
  ##################
  
  res_eval<-NULL
  res_comp<-NULL
  res_eval_plots_cross<-list()
  res_eval_plots_indep<-list()
  res_eval_diff_plots_cross<-list()
  res_eval_diff_plots_indep<-list()
  res_eval_diff_matrix_cross<-list()
  res_eval_diff_matrix_indep<-list()
  for(i in 1:length(pheno)){
      res_eval_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.pred_eval.txt'), header=T, stringsAsFactors=F)
  
      res_comp_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.pred_comp.txt'), header=T, stringsAsFactors=F)

    # Idenitfy model names for 10FCVal, multi-PRS and pseudoval
    selected_models<-NULL
    
    ##
    # pT+clump (sparse)
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_pT<-res_eval_i[grepl('pT.clump.PredFile', res_eval_i$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='pT+clump.10FCVal', Label=
    res_eval_i_per_pT[res_eval_i_per_pT$CrossVal_R == max(res_eval_i_per_pT$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='pT+clump.MultiPRS', Label='pT.clump'))
  
    ##
    # lassosum
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_lassosum<-res_eval_i[grepl('lassosum.PredFile', res_eval_i$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.10FCVal', Label=
    res_eval_i_per_lassosum[res_eval_i_per_lassosum$CrossVal_R == max(res_eval_i_per_lassosum$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.MultiPRS', Label='lassosum'))
  
    # Identify pseudoVal
    lassosum_val<-read.table(paste0('/users/k1806347/brc_scratch/Data/1KG/Phase3/Score_files_for_polygenic/lassosum/',gwas[i],'/1KGPhase3.w_hm3.',gwas[i],'.log'), sep='&')
    lassosum_val_s<-as.numeric(gsub('s = ','',lassosum_val$V1[grepl('s = ',lassosum_val$V1)]))
    lassosum_val_lambda<-as.numeric(gsub('lambda =','',lassosum_val$V1[grepl('lambda =',lassosum_val$V1)]))
    lassosum_val_param<-paste0('s',lassosum_val_s,'.lambda',lassosum_val_lambda)
    lassosum_val_param<-substr(lassosum_val_param, 1, nchar(lassosum_val_param)-1) 
  
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.PseudoVal', Label=res_eval_i[grepl(lassosum_val_param, res_eval_i$Model),]$Model[1]))
    
    ##
    # PRScs
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_PRScs<-res_eval_i[grepl('PRScs.PredFile', res_eval_i$Model),]
    res_eval_i_per_PRScs<-res_eval_i_per_PRScs[!grepl('phiauto', res_eval_i_per_PRScs$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.10FCVal', Label=res_eval_i_per_PRScs[res_eval_i_per_PRScs$CrossVal_R == max(res_eval_i_per_PRScs$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.MultiPRS', Label='PRScs'))
  
    # Identify pseudoval
    res_eval_i_per_PRScs<-res_eval_i[grepl('PRScs.PredFile', res_eval_i$Model),]
    res_eval_i_per_PRScs<-res_eval_i_per_PRScs[grepl('phiauto', res_eval_i_per_PRScs$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.PseudoVal', Label=res_eval_i_per_PRScs[res_eval_i_per_PRScs$CrossVal_R == max(res_eval_i_per_PRScs$CrossVal_R),]$Model[1]))
  
    ##
    # SBLUP
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='SBLUP.Inf', Label='SBLUP'))
    
    ##
    # SBayesR
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='SBayesR.PseudoVal', Label='SBayesR'))
  
    ##
    # LDPred1
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_LDPred<-res_eval_i[grepl('LDPred.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred<-res_eval_i_per_LDPred[!grepl('.LDpred.inf', res_eval_i_per_LDPred$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.10FCVal', Label=res_eval_i_per_LDPred[res_eval_i_per_LDPred$CrossVal_R == max(res_eval_i_per_LDPred$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.MultiPRS', Label='LDPred'))
  
    # Identify pseudoval
    res_eval_i_per_LDPred<-res_eval_i[grepl('LDPred.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred<-res_eval_i_per_LDPred[grepl('.LDpred.inf', res_eval_i_per_LDPred$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.Inf', Label=res_eval_i_per_LDPred[res_eval_i_per_LDPred$CrossVal_R == max(res_eval_i_per_LDPred$CrossVal_R),]$Model[1]))
  
    ##
    # LDPred2
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[!grepl('beta.inf|beta.auto', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.10FCVal', Label=res_eval_i_per_LDPred2[res_eval_i_per_LDPred2$CrossVal_R == max(res_eval_i_per_LDPred2$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.MultiPRS', Label='LDPred2'))
  
    # Identify pseudoval
    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[grepl('beta.inf', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.Inf', Label=res_eval_i_per_LDPred2$Model))

    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[grepl('beta.auto', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.PseudoVal', Label=res_eval_i_per_LDPred2$Model))
  
    ##
    # DBSLMM
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='DBSLMM.PseudoVal', Label='DBSLMM'))

    ##
    # All methods
    ##
    
    selected_models<-rbind(selected_models,data.frame(Test='All.MultiPRS', Label='All'))

    ###
    # Subset selected models and format
    ###
    
    # Eval
    selected_models$Label_2<-paste0(gsub('_group','',selected_models$Label),'_group')
    res_eval_i_select<-res_eval_i[(res_eval_i$Model %in% selected_models$Label_2),]
    res_eval_i_select<-merge(res_eval_i_select, selected_models[c('Test','Label_2')], by.x='Model',by.y='Label_2')
    res_eval_i_select$Phenotype<-pheno[i]
    if(sum(names(res_eval_i_select) == 'CrossVal_OR') == 0){
      res_eval_i_select$CrossVal_OR<-NA
      res_eval_i_select$CrossVal_LowCI<-NA
      res_eval_i_select$CrossVal_HighCI<-NA
      res_eval_i_select$Cross_LiabR2<-NA
      res_eval_i_select$Cross_AUC<-NA
      res_eval_i_select$CrossVal_Ncas<-NA
      res_eval_i_select$CrossVal_Ncon<-NA
      
      res_eval_i_select$IndepVal_OR<-NA
      res_eval_i_select$IndepVal_LowCI<-NA
      res_eval_i_select$IndepVal_HighCI<-NA
      res_eval_i_select$Indep_LiabR2<-NA
      res_eval_i_select$Indep_AUC<-NA
      res_eval_i_select$IndepVal_Ncas<-NA
      res_eval_i_select$IndepVal_Ncon<-NA
    }
    
    res_eval_i_select<-res_eval_i_select[c('Phenotype','Test',"CrossVal_R","CrossVal_R_SE",'CrossVal_OR','CrossVal_LowCI','CrossVal_HighCI','Cross_LiabR2','Cross_AUC','CrossVal_pval','CrossVal_N','CrossVal_Ncas','CrossVal_Ncon',"IndepVal_R","IndepVal_R_SE",'IndepVal_OR','IndepVal_LowCI','IndepVal_HighCI','Indep_LiabR2','Indep_AUC','IndepVal_pval','IndepVal_N','IndepVal_Ncas','IndepVal_Ncon')]
    
    res_eval<-rbind(res_eval,res_eval_i_select)
    
    # Comp
    selected_models$Label_3<-gsub('_group','',selected_models$Label)
    res_comp_i_select<-res_comp_i[(res_comp_i$Model_1 %in% selected_models$Label_3) & (res_comp_i$Model_2 %in% selected_models$Label_3),]
    res_comp_i_select<-merge(res_comp_i_select, selected_models[c('Test','Label_3')], by.x='Model_1',by.y='Label_3')
    names(res_comp_i_select)[names(res_comp_i_select) == 'Test']<-'Model_1_Test'
    res_comp_i_select<-merge(res_comp_i_select, selected_models[c('Test','Label_3')], by.x='Model_2',by.y='Label_3')
    names(res_comp_i_select)[names(res_comp_i_select) == 'Test']<-'Model_2_Test'
    res_comp_i_select$Label<-NULL
    res_comp_i_select$Phenotype<-pheno[i]
    res_comp_i_select<-res_comp_i_select[c('Phenotype','Model_1_Test','Model_2_Test','Model_1_Cross_R','Model_2_Cross_R','Cross_R_diff','Cross_R_diff_pval','Model_1_Indep_R','Model_2_Indep_R','Indep_R_diff','Indep_R_diff_pval')]
  
    res_comp<-rbind(res_comp,res_comp_i_select)
  }
  
  ###################
  # Average results across phenotypes, creates tables and figures
  ###################
  
  res_eval$Method<-gsub('\\..*','',res_eval$Test)
  res_eval$Model<-gsub('.*\\.','',res_eval$Test)
  
  res_eval$Phenotype<-factor(res_eval$Phenotype, level=unique(res_eval$Phenotype))
  res_eval$Method<-factor(res_eval$Method, level=c("pT+clump",'lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
  res_eval$Model<-factor(res_eval$Model, level=c('10FCVal','MultiPRS','PseudoVal','Inf'))
  
  res_eval<-res_eval[order(res_eval$Phenotype, res_eval$Method, res_eval$Model),]
  
  library(data.table)
  source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')
  
  for(pheno_i in 1:length(pheno)){
    if(pheno_i==1){
      pheno_i_dat<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',pheno[pheno_i],'.txt'))
      names(pheno_i_dat)[3]<-pheno[pheno_i]
      pheno_dat<-pheno_i_dat
    } else {
      pheno_i_dat<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',pheno[pheno_i],'.txt'))
      names(pheno_i_dat)[3]<-pheno[pheno_i]
      pheno_dat<-merge(pheno_dat, pheno_i_dat, by=c('FID','IID'), all=T)
    }
  }

  # Calculate corelation between all phenotypes
  cors<-abs(cor(as.matrix(pheno_dat[,-1:-2]), use='p'))
  cors<-cors[unique(res_eval$Phenotype,),unique(res_eval$Phenotype,)]
  cors[is.na(cors)]<-0
  
  # Run aggregate function
  library(MAd)
  meta_res_eval<-NULL
  for(i in unique(res_eval$Test)){
    res_eval_i<-res_eval[res_eval$Test == i,]
    res_eval_i$Sample<-'Target'
    
    cors_i<-cors[(dimnames(cors)[[1]] %in% res_eval_i$Phenotype),(dimnames(cors)[[1]] %in% res_eval_i$Phenotype)]
  
    CrossVal_agg_res_eval_i<-agg(id=Sample, es=CrossVal_R, var=CrossVal_R_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_eval_i)
    IndepVal_agg_res_eval_i<-agg(id=Sample, es=IndepVal_R, var=IndepVal_R_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_eval_i)
  
    meta_res_eval<-rbind(meta_res_eval, data.frame(  Test=i,
                                           CrossVal_R=CrossVal_agg_res_eval_i$es[1],
                                           CrossVal_R_SE=sqrt(CrossVal_agg_res_eval_i$var[1]),
                                           IndepVal_R=IndepVal_agg_res_eval_i$es[1],
                                           IndepVal_R_SE=sqrt(IndepVal_agg_res_eval_i$var[1])))
  }
  
  # Calculate difference between methods and p-value using aggregate
  # Truncate difference p-values to stop 0 values
  res_comp$Cross_R_diff_pval[res_comp$Cross_R_diff_pval == 0]<-1e-320
  res_comp$Indep_R_diff_pval[res_comp$Indep_R_diff_pval == 0]<-1e-320
  
  meta_res_diff<-NULL
  for(i in unique(res_eval$Test)){
    for(k in unique(res_eval$Test)){
      meta_res_eval_i<-meta_res_eval[meta_res_eval$Test == i,]
      meta_res_eval_k<-meta_res_eval[meta_res_eval$Test == k,]
  
      res_comp_i_k<-res_comp[res_comp$Model_1_Test == i & res_comp$Model_2_Test == k,]
      
      # Calculate diff SE based on p-value
      for(j in 1:dim(res_comp_i_k)[1]){
        if(res_comp_i_k$Cross_R_diff_pval[j] == 1){
          res_comp_i_k$Cross_R_diff_pval[j]<-1-0.001
        }
        if(res_comp_i_k$Indep_R_diff_pval[j] == 1){
          res_comp_i_k$Indep_R_diff_pval[j]<-1-0.001
        }
      }

      res_comp_i_k$Cross_R_diff_z<-qnorm(res_comp_i_k$Cross_R_diff_pval/2)
      res_comp_i_k$Cross_R_diff_SE<-res_comp_i_k$Cross_R_diff/res_comp_i_k$Cross_R_diff_z
  
      res_comp_i_k$Indep_R_diff_z<-qnorm(res_comp_i_k$Indep_R_diff_pval/2)
      res_comp_i_k$Indep_R_diff_SE<-res_comp_i_k$Indep_R_diff/res_comp_i_k$Indep_R_diff_z
      
      res_comp_i_k$Sample<-'A'
      
      cors_i<-cors[(dimnames(cors)[[1]] %in% res_comp_i_k$Phenotype),(dimnames(cors)[[1]] %in% res_comp_i_k$Phenotype)]

      CrossVal_agg_res_comp_i_k<-agg(id=Sample, es=Cross_R_diff, var=Cross_R_diff_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_comp_i_k)
      
      IndepVal_agg_res_eval_i<-agg(id=Sample, es=Indep_R_diff, var=Indep_R_diff_SE^2, cor=cors_i, method="BHHR", mod=NULL, data=res_comp_i_k)
    
      meta_res_diff<-rbind(meta_res_diff, data.frame(Test_ref=i,
                                                     Test_targ=k,
                                                     CrossVal_R_diff=CrossVal_agg_res_comp_i_k$es[1],
                                                     CrossVal_R_diff_SE=sqrt(CrossVal_agg_res_comp_i_k$var[1]),
                                                     IndepVal_R_diff=IndepVal_agg_res_eval_i$es[1],
                                                     IndepVal_R_diff_SE=sqrt(IndepVal_agg_res_eval_i$var[1])))
    }
  }
                                           
  meta_res_diff$CrossVal_R_diff_Z<-meta_res_diff$CrossVal_R_diff/meta_res_diff$CrossVal_R_diff_SE
  meta_res_diff$CrossVal_R_diff_P<-2*pnorm(-abs(meta_res_diff$CrossVal_R_diff_Z))              
  meta_res_diff$IndepVal_R_diff_Z<-meta_res_diff$IndepVal_R_diff/meta_res_diff$IndepVal_R_diff_SE
  meta_res_diff$IndepVal_R_diff_P<-2*pnorm(-abs(meta_res_diff$IndepVal_R_diff_Z))              
  meta_res_diff<-meta_res_diff[,c("Test_ref","Test_targ","CrossVal_R_diff","CrossVal_R_diff_Z","CrossVal_R_diff_P","IndepVal_R_diff","IndepVal_R_diff_Z","IndepVal_R_diff_P")]
  
  meta_res_diff$CrossVal_R_diff_Z[meta_res_diff$CrossVal_R_diff == 0]<-0
  meta_res_diff$CrossVal_R_diff_P[meta_res_diff$CrossVal_R_diff == 0]<-1
  meta_res_diff$IndepVal_R_diff_Z[meta_res_diff$IndepVal_R_diff == 0]<-0
  meta_res_diff$IndepVal_R_diff_P[meta_res_diff$IndepVal_R_diff == 0]<-1
  
  # Calculate percentage improvement
  meta_res_diff$CrossVal_R_diff_perc<-NA
  for(i in unique(meta_res_diff$Test_ref)){
    meta_res_diff$CrossVal_R_diff_perc[meta_res_diff$Test_ref == i]<-meta_res_diff$CrossVal_R_diff[meta_res_diff$Test_ref == i]/meta_res_eval$CrossVal_R[meta_res_eval$Test == i]*100
  }
  
  meta_res_diff$IndepVal_R_diff_perc<-NA
  for(i in unique(meta_res_diff$Test_ref)){
    meta_res_diff$IndepVal_R_diff_perc[meta_res_diff$Test_ref == i]<-meta_res_diff$IndepVal_R_diff[meta_res_diff$Test_ref == i]/meta_res_eval$IndepVal_R[meta_res_eval$Test == i]*100
  }
  
  write.csv(meta_res_eval, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'_meta_.csv'), row.names=F, quote=F)
  
  meta_res_diff<-meta_res_diff[,c("Test_ref","Test_targ","CrossVal_R_diff",'CrossVal_R_diff_perc',"CrossVal_R_diff_Z","CrossVal_R_diff_P","IndepVal_R_diff",'IndepVal_R_diff_perc',"IndepVal_R_diff_Z","IndepVal_R_diff_P")]    
  
  write.csv(meta_res_diff, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_method_comp_',Files[file],'_diff_meta.csv'), row.names=F, quote=F)
  
  ###
  # Create plot showing performance of each method
  ###
  
  # To avoid unequal groups, insert NA for missing Model/Method pairs
  meta_res_eval$Method<-gsub('\\..*','',meta_res_eval$Test)
  meta_res_eval$Model<-gsub('.*\\.','',meta_res_eval$Test)

  meta_res_eval$Method<-factor(meta_res_eval$Method, levels=c("pT+clump",'lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
  meta_res_eval$Model<-factor(meta_res_eval$Model, levels=c('10FCVal','MultiPRS','PseudoVal','Inf'))

  for(i in unique(meta_res_eval$Method)){
    for(k in unique(meta_res_eval$Model)){
      if(dim(meta_res_eval[meta_res_eval$Method == i & meta_res_eval$Model == k,])[1] > 0){
        next
      } else {
        dud<-data.frame(Test=NA,
                        CrossVal_R=NA,
                        CrossVal_R_SE=NA,
                        IndepVal_R=NA,
                        IndepVal_R_SE=NA,
                        Method=i,
                        Model=k)
        meta_res_eval<-rbind(meta_res_eval,dud)
      }
    }
  }
  
  res_eval<-res_eval[,c('Phenotype','Test','CrossVal_R','IndepVal_R','Method','Model')]
  
  for(i in unique(res_eval$Method)){
    for(k in unique(res_eval$Model)){
      if(dim(res_eval[res_eval$Method == i & res_eval$Model == k,])[1] > 0){
        next
      } else {
        dud<-data.frame(Phenotype=NA,
                        Test=paste0(i,'.',k),
                        CrossVal_R=NA,
                        IndepVal_R=NA,
                        Method=i,
                        Model=k)
        res_eval<-rbind(res_eval,dud)
      }
    }
  }
  
  library(ggplot2)
  library(cowplot)
  
  meta_res_eval_plots_cross[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=CrossVal_R, fill=Model)) +
                        geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                        geom_errorbar(aes(ymin=CrossVal_R-CrossVal_R_SE, ymax=CrossVal_R+CrossVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                        labs(y="Correlation (SE)", x='', title=Files_descrip[file]) +
                        theme_half_open() +
                              theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                              geom_vline(xintercept = 1.5, linetype="dotted") +
                              geom_vline(xintercept = 2.5, linetype="dotted") + 
                              geom_vline(xintercept = 3.5, linetype="dotted") + 
                              geom_vline(xintercept = 4.5, linetype="dotted") + 
                              geom_vline(xintercept = 5.5, linetype="dotted") +
                              geom_vline(xintercept = 6.5, linetype="dotted") +
                              geom_vline(xintercept = 7.5, linetype="dotted") +
                              geom_vline(xintercept = 8.5, linetype="dotted") +
                        background_grid(major = 'y', minor = 'y')

  meta_res_eval_plots_indep[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=IndepVal_R, fill=Model)) +
                        geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                        geom_errorbar(aes(ymin=IndepVal_R-IndepVal_R_SE, ymax=IndepVal_R+IndepVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                        labs(y="Correlation (SE)", x='', title=Files_descrip[file]) +
                        theme_half_open() +
                              theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                              geom_vline(xintercept = 1.5, linetype="dotted") +
                              geom_vline(xintercept = 2.5, linetype="dotted") + 
                              geom_vline(xintercept = 3.5, linetype="dotted") + 
                              geom_vline(xintercept = 4.5, linetype="dotted") + 
                              geom_vline(xintercept = 5.5, linetype="dotted") +
                              geom_vline(xintercept = 6.5, linetype="dotted") +
                              geom_vline(xintercept = 7.5, linetype="dotted") +
                              geom_vline(xintercept = 8.5, linetype="dotted") +
                        background_grid(major = 'y', minor = 'y')
  
  if(Samples[file] == 'UKBB'){
    meta_res_eval_plots_cross[[Files[file]]]<-meta_res_eval_plots_cross[[Files[file]]] + coord_cartesian(ylim=c(0,0.25), clip="on")
    meta_res_eval_plots_indep[[Files[file]]]<-meta_res_eval_plots_indep[[Files[file]]] + coord_cartesian(ylim=c(0,0.25), clip="on")
  } else {
    meta_res_eval_plots_cross[[Files[file]]]<-meta_res_eval_plots_cross[[Files[file]]] + coord_cartesian(ylim=c(0,0.375), clip="on")
    meta_res_eval_plots_indep[[Files[file]]]<-meta_res_eval_plots_indep[[Files[file]]] + coord_cartesian(ylim=c(0,0.375), clip="on")
  }                           

  ###
  # Create plot showing performance of each method compared to pT+clump
  ###
  
    # Calculate differences at the average and phenotype specific level
    meta_res_eval$CrossVal_R_diff<-meta_res_eval$CrossVal_R-meta_res_eval$CrossVal_R[which(meta_res_eval$Test == "pT+clump.10FCVal")]
    
    meta_res_eval$IndepVal_R_diff<-meta_res_eval$IndepVal_R-meta_res_eval$IndepVal_R[which(meta_res_eval$Test == "pT+clump.10FCVal")]
    
    res_eval$CrossVal_R_diff<-NA
    res_eval$IndepVal_R_diff<-NA
    for(i in pheno){
        res_eval$CrossVal_R_diff[which(res_eval$Phenotype == i)]<-res_eval$CrossVal_R[which(res_eval$Phenotype == i)]-res_eval$CrossVal_R[which(res_eval$Test == "pT+clump.10FCVal" & res_eval$Phenotype == i)]
    
        res_eval$IndepVal_R_diff[which(res_eval$Phenotype == i)]<-res_eval$IndepVal_R[which(res_eval$Phenotype == i)]-res_eval$IndepVal_R[which(res_eval$Test == "pT+clump.10FCVal" & res_eval$Phenotype == i)]
    }

    meta_res_eval_diff_plots_cross[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=CrossVal_R_diff, fill=Model)) +
                          geom_point(data=res_eval, mapping=aes(x=Method, y=CrossVal_R_diff, colour=Model), position=position_jitterdodge(jitter.width = 0.4, dodge.width = 0.7), alpha=0.3) +
                        geom_errorbar(aes(ymin=CrossVal_R_diff-CrossVal_R_SE, ymax=CrossVal_R_diff+CrossVal_R_SE), width=0.7, position=position_dodge(width = 0.7)) +
                          geom_point(stat="identity", position=position_dodge(0.7), size=2, shape=23, colour='black') +
                          labs(y="Difference in\nCorrelations (SE)", x='', title=Files_descrip[file]) +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                                  geom_vline(xintercept = 1.5, linetype="dotted") +
                                  geom_vline(xintercept = 2.5, linetype="dotted") + 
                                  geom_vline(xintercept = 3.5, linetype="dotted") + 
                                  geom_vline(xintercept = 4.5, linetype="dotted") + 
                                  geom_vline(xintercept = 5.5, linetype="dotted") +
                                  geom_vline(xintercept = 6.5, linetype="dotted") +
                                  geom_vline(xintercept = 7.5, linetype="dotted") +
                                  geom_vline(xintercept = 8.5, linetype="dotted") +
                          background_grid(major = 'y', minor = 'y') +
                          ylim(c(-0.12,0.12))
                              
    meta_res_eval_diff_plots_indep[[Files[file]]] <- ggplot(meta_res_eval, aes(x=Method, y=IndepVal_R_diff, fill=Model)) +
                          geom_point(data=res_eval, mapping=aes(x=Method, y=IndepVal_R_diff, colour=Model), position=position_jitterdodge(jitter.width = 0.4, dodge.width = 1), alpha=0.3) +
                          geom_errorbar(aes(ymin=IndepVal_R_diff-IndepVal_R_SE, ymax=IndepVal_R_diff+IndepVal_R_SE), width=0.7, position=position_dodge(width = 1)) +
                          geom_point(stat="identity", position=position_dodge(1), size=2, shape=23, colour='black') +
                          labs(y="Difference in\nCorrelations (SE)", x='', title=Files_descrip[file]) +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                                  geom_vline(xintercept = 1.5, linetype="dotted") +
                                  geom_vline(xintercept = 2.5, linetype="dotted") + 
                                  geom_vline(xintercept = 3.5, linetype="dotted") + 
                                  geom_vline(xintercept = 4.5, linetype="dotted") + 
                                  geom_vline(xintercept = 5.5, linetype="dotted") +
                                  geom_vline(xintercept = 6.5, linetype="dotted") +
                                  geom_vline(xintercept = 7.5, linetype="dotted") +
                                  geom_vline(xintercept = 8.5, linetype="dotted") +
                          background_grid(major = 'y', minor = 'y') +
                          ylim(c(-0.12,0.12))

  ###
  # Create plot showing matrix of differences with significance
  ###
  
  library(reshape2)
  
  meta_res_diff$CrossVal_R_diff[meta_res_diff$Test_ref == meta_res_diff$Test_targ]<-NA
  meta_res_diff$IndepVal_R_diff[meta_res_diff$Test_ref == meta_res_diff$Test_targ]<-NA
  
  meta_res_diff$Cross_R_diff_catagory<-'NA'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.002]<-'-0.025 - -0.002'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.025]<-'-0.08 - -0.025'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.08]<-'< -0.08'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > -0.002 & meta_res_diff$CrossVal_R_diff < 0.002]<-'-0.002 - 0.002'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.002]<-'0.002 - 0.025'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.025]<-'0.025 - 0.08'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.08]<-'> 0.08'
  
  meta_res_diff$Cross_R_diff_catagory<-factor(meta_res_diff$Cross_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
  meta_res_diff$Indep_R_diff_catagory<-'NA'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.002]<-'-0.025 - -0.002'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.025]<-'-0.08 - -0.025'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.08]<-'< -0.08'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > -0.002 & meta_res_diff$IndepVal_R_diff < 0.002]<-'-0.002 - 0.002'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.002]<-'0.002 - 0.025'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.025]<-'0.025 - 0.08'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.08]<-'> 0.08'
  
  meta_res_diff$Indep_R_diff_catagory<-factor(meta_res_diff$Indep_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
  meta_res_diff$cross_star<-' '
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 0.05]<-'*'
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 1e-3]<-'**'
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 1e-6]<-'***'
  
  meta_res_diff$indep_star<-' '
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 0.05]<-'*'
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 1e-3]<-'**'
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 1e-6]<-'***'
  
  library(RColorBrewer)
  meta_res_eval_diff_matrix_cross[[Files[file]]]<-ggplot(data = meta_res_diff, aes(Test_targ, Test_ref, fill=Cross_R_diff_catagory))+
   geom_tile(color = "white")+
   labs(y='Test', x='Comparison', title=Files_descrip[file], fill='R difference') +
    theme_minimal()+ 
   theme(axis.text.x = element_text(angle = 45, vjust = 1, 
      size = 8, hjust = 1)) +
   coord_fixed() +
  geom_text(data=meta_res_diff, aes(Test_ref, Test_targ, label = cross_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(meta_res_diff$Cross_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')
  
  meta_res_eval_diff_matrix_indep[[Files[file]]]<-ggplot(data = meta_res_diff, aes(Test_targ, Test_ref, fill=Indep_R_diff_catagory))+
   geom_tile(color = "white")+
   labs(y='Test', x='Comparison', title=Files_descrip[file], fill='R difference') +
    theme_minimal()+ 
   theme(axis.text.x = element_text(angle = 45, vjust = 1, 
      size = 8, hjust = 1))+
   coord_fixed() +
  geom_text(data=meta_res_diff, aes(Test_targ, Test_ref, label = indep_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(meta_res_diff$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')

}

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_CrossVal_meta_byPoly.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_plots_cross, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_IndepVal_meta_byPoly.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_plots_indep, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_pTDiff_CrossVal_meta_byPoly.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_diff_plots_cross, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_pTDiff_IndepVal_meta_byPoly.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_diff_plots_indep, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_diff_CrossVal_meta_byPoly.png', units='px', res=300, width=4000, height=2000)
plot_grid(plotlist=meta_res_eval_diff_matrix_cross, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PRS_method_comp_diff_IndepVal_meta_byPoly.png', units='px', res=300, width=4000, height=2000)
plot_grid(plotlist=meta_res_eval_diff_matrix_indep, ncol = 2, nrow = 1)
dev.off()

Summarise and plot the results with PCs regressed

Files<-c('UKBB','TEDS')
Samples<-c('UKBB','TEDS')
Files_descrip<-c('UKB target with 1KG ref','TEDS target with 1KG ref')

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

meta_res_eval<-NULL
meta_res_comp<-NULL
meta_res_eval_plots_cross<-list()
meta_res_eval_plots_indep<-list()
meta_res_eval_diff_plots_cross<-list()
meta_res_eval_diff_plots_indep<-list()
meta_res_eval_diff_matrix_cross<-list()
meta_res_eval_diff_matrix_indep<-list()

for(file in 1:length(Files)){
    if(Samples[file] == 'UKBB'){
      pheno<-c('Depression','Intelligence','Height','BMI','T2D','CAD','IBD', 'MultiScler','RheuArth','Prostate_Cancer','Breast_Cancer')
      gwas<-c('DEPR06','COLL01','HEIG03','BODY04','DIAB05','COAD01','CROH01','SCLE03','RHEU02','PRCA01','BRCA01')
    } else {
      pheno<-c('Height21', 'BMI21', 'GCSE', 'ADHD')
      gwas<-c('HEIG03', 'BODY11', 'EDUC03', 'ADHD04')
    }
   
  ##################
  # Organise, make tables and figures for per phenotype results
  ##################
  
  res_eval<-NULL
  res_comp<-NULL
  res_eval_plots_cross<-list()
  res_eval_plots_indep<-list()
  res_eval_diff_plots_cross<-list()
  res_eval_diff_plots_indep<-list()
  res_eval_diff_matrix_cross<-list()
  res_eval_diff_matrix_indep<-list()
  for(i in 1:length(pheno)){
    res_eval_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.PCresid.pred_eval.txt'), header=T, stringsAsFactors=F)
  
    res_comp_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs.AllMethodComp.PCresid.pred_comp.txt'), header=T, stringsAsFactors=F)

    # Idenitfy model names for 10FCVal, multi-PRS and pseudoval
    selected_models<-NULL
    
    ##
    # pT+clump (sparse)
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_pT<-res_eval_i[grepl('pT.clump.PredFile', res_eval_i$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='pT+clump.10FCVal', Label=
    res_eval_i_per_pT[res_eval_i_per_pT$CrossVal_R == max(res_eval_i_per_pT$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='pT+clump.MultiPRS', Label='pT.clump'))
  
    ##
    # lassosum
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_lassosum<-res_eval_i[grepl('lassosum.PredFile', res_eval_i$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.10FCVal', Label=
    res_eval_i_per_lassosum[res_eval_i_per_lassosum$CrossVal_R == max(res_eval_i_per_lassosum$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.MultiPRS', Label='lassosum'))
  
    # Identify pseudoVal
    lassosum_val<-read.table(paste0('/users/k1806347/brc_scratch/Data/1KG/Phase3/Score_files_for_polygenic/lassosum/',gwas[i],'/1KGPhase3.w_hm3.',gwas[i],'.log'), sep='&')
    lassosum_val_s<-as.numeric(gsub('s = ','',lassosum_val$V1[grepl('s = ',lassosum_val$V1)]))
    lassosum_val_lambda<-as.numeric(gsub('lambda =','',lassosum_val$V1[grepl('lambda =',lassosum_val$V1)]))
    lassosum_val_param<-paste0('s',lassosum_val_s,'.lambda',lassosum_val_lambda)
    lassosum_val_param<-substr(lassosum_val_param, 1, nchar(lassosum_val_param)-1) 
  
    selected_models<-rbind(selected_models,data.frame(Test='lassosum.PseudoVal', Label=res_eval_i[grepl(lassosum_val_param, res_eval_i$Model),]$Model[1]))
    
    ##
    # PRScs
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_PRScs<-res_eval_i[grepl('PRScs.PredFile', res_eval_i$Model),]
    res_eval_i_per_PRScs<-res_eval_i_per_PRScs[!grepl('phiauto', res_eval_i_per_PRScs$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.10FCVal', Label=res_eval_i_per_PRScs[res_eval_i_per_PRScs$CrossVal_R == max(res_eval_i_per_PRScs$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.MultiPRS', Label='PRScs'))
  
    # Identify pseudoval
    res_eval_i_per_PRScs<-res_eval_i[grepl('PRScs.PredFile', res_eval_i$Model),]
    res_eval_i_per_PRScs<-res_eval_i_per_PRScs[grepl('phiauto', res_eval_i_per_PRScs$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='PRScs.PseudoVal', Label=res_eval_i_per_PRScs[res_eval_i_per_PRScs$CrossVal_R == max(res_eval_i_per_PRScs$CrossVal_R),]$Model[1]))
  
    ##
    # SBLUP
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='SBLUP.Inf', Label='SBLUP'))
    
    ##
    # SBayesR
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='SBayesR.PseudoVal', Label='SBayesR'))
  
    ##
    # LDPred1
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_LDPred<-res_eval_i[grepl('LDPred.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred<-res_eval_i_per_LDPred[!grepl('.LDpred.inf', res_eval_i_per_LDPred$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.10FCVal', Label=res_eval_i_per_LDPred[res_eval_i_per_LDPred$CrossVal_R == max(res_eval_i_per_LDPred$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.MultiPRS', Label='LDPred'))
  
    # Identify pseudoval
    res_eval_i_per_LDPred<-res_eval_i[grepl('LDPred.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred<-res_eval_i_per_LDPred[grepl('.LDpred.inf', res_eval_i_per_LDPred$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred1.Inf', Label=res_eval_i_per_LDPred[res_eval_i_per_LDPred$CrossVal_R == max(res_eval_i_per_LDPred$CrossVal_R),]$Model[1]))
  
    ##
    # LDPred2
    ##
    
    # Identify best pT in 10FCVal
    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[!grepl('beta.inf|beta.auto', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.10FCVal', Label=res_eval_i_per_LDPred2[res_eval_i_per_LDPred2$CrossVal_R == max(res_eval_i_per_LDPred2$CrossVal_R),]$Model[1]))
  
    # Identify multi pT
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.MultiPRS', Label='LDPred2'))
  
    # Identify pseudoval
    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[grepl('beta.inf', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.Inf', Label=res_eval_i_per_LDPred2$Model))

    res_eval_i_per_LDPred2<-res_eval_i[grepl('LDPred2.PredFile', res_eval_i$Model),]
    res_eval_i_per_LDPred2<-res_eval_i_per_LDPred2[grepl('beta.auto', res_eval_i_per_LDPred2$Model),]
    selected_models<-rbind(selected_models,data.frame(Test='LDpred2.PseudoVal', Label=res_eval_i_per_LDPred2$Model))
 
    ##
    # DBSLMM
    ##
    
    # Identify PseudoVal
    selected_models<-rbind(selected_models,data.frame(Test='DBSLMM.PseudoVal', Label='DBSLMM'))

    ##
    # All methods
    ##
    
    selected_models<-rbind(selected_models,data.frame(Test='All.MultiPRS', Label='All'))

    ###
    # Subset selected models and format
    ###
    
    # Eval
    selected_models$Label_2<-paste0(gsub('_group','',selected_models$Label),'_group')
    res_eval_i_select<-res_eval_i[(res_eval_i$Model %in% selected_models$Label_2),]
    res_eval_i_select<-merge(res_eval_i_select, selected_models[c('Test','Label_2')], by.x='Model',by.y='Label_2')
    res_eval_i_select$Phenotype<-pheno[i]
    res_eval_i_select<-res_eval_i_select[c('Phenotype','Test',"CrossVal_R","CrossVal_R_SE","CrossVal_pval","IndepVal_R","IndepVal_R_SE","IndepVal_pval")]
    
    res_eval<-rbind(res_eval,res_eval_i_select)
    
    # Comp
    selected_models$Label_3<-gsub('_group','',selected_models$Label)
    res_comp_i_select<-res_comp_i[(res_comp_i$Model_1 %in% selected_models$Label_3) & (res_comp_i$Model_2 %in% selected_models$Label_3),]
    res_comp_i_select<-merge(res_comp_i_select, selected_models[c('Test','Label_3')], by.x='Model_1',by.y='Label_3')
    names(res_comp_i_select)[names(res_comp_i_select) == 'Test']<-'Model_1_Test'
    res_comp_i_select<-merge(res_comp_i_select, selected_models[c('Test','Label_3')], by.x='Model_2',by.y='Label_3')
    names(res_comp_i_select)[names(res_comp_i_select) == 'Test']<-'Model_2_Test'
    res_comp_i_select$Label<-NULL
    res_comp_i_select$Phenotype<-pheno[i]
    res_comp_i_select<-res_comp_i_select[c('Phenotype','Model_1_Test','Model_2_Test','Model_1_Cross_R','Model_2_Cross_R','Cross_R_diff','Cross_R_diff_pval','Model_1_Indep_R','Model_2_Indep_R','Indep_R_diff','Indep_R_diff_pval')]
  
    res_comp<-rbind(res_comp,res_comp_i_select)
    
    ###
    # Create plot showing performance of each method
    ###
    
    library(ggplot2)
    library(cowplot)
    
    res_eval_i_select$Method<-gsub('\\..*','',res_eval_i_select$Test)
    res_eval_i_select$Model<-gsub('.*\\.','',res_eval_i_select$Test)
    
    res_eval_i_select$Method<-factor(res_eval_i_select$Method, levels=c('pT+clump','lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
    res_eval_i_select$Model<-factor(res_eval_i_select$Model, levels=c('10FCVal','MultiPRS','PseudoVal','Inf'))
    
    res_eval_plots_cross[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=CrossVal_R, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=CrossVal_R-CrossVal_R_SE, ymax=CrossVal_R+CrossVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$CrossVal_R[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$CrossVal_R[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y')
                                  
    res_eval_plots_indep[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=IndepVal_R, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=IndepVal_R-IndepVal_R_SE, ymax=IndepVal_R+IndepVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$IndepVal_R[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$IndepVal_R[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y')

    ###
    # Create plot showing performance of each method compared to pT+clump
    ###
  
    res_eval_i_select$CrossVal_R_diff<-res_eval_i_select$CrossVal_R-res_eval_i_select$CrossVal_R[res_eval_i_select$Test == "pT+clump.10FCVal"]
    
    res_eval_diff_plots_cross[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=CrossVal_R_diff, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=CrossVal_R_diff-CrossVal_R_SE, ymax=CrossVal_R_diff+CrossVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$CrossVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$CrossVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y')
    
    res_eval_i_select$IndepVal_R_diff<-res_eval_i_select$IndepVal_R-res_eval_i_select$IndepVal_R[res_eval_i_select$Test == "pT+clump.10FCVal"]
                              
    res_eval_diff_plots_indep[[pheno[i]]] <- ggplot( res_eval_i_select, aes(x=Method, y=IndepVal_R_diff, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=IndepVal_R_diff-IndepVal_R_SE, ymax=IndepVal_R_diff+IndepVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res_eval_i_select$IndepVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])-0.02, max(res_eval_i_select$IndepVal_R_diff[res_eval_i_select$Phenotype==pheno[i]])+0.025), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y')
  
    ###
    # Create plot showing matrix of differences with significance
    ###
  
    library(reshape2)
    
    res_comp_i_select$Cross_R_diff[res_comp_i_select$Model_1_Test == res_comp_i_select$Model_2_Test]<-NA
    res_comp_i_select$Indep_R_diff[res_comp_i_select$Model_1_Test == res_comp_i_select$Model_2_Test]<-NA

    res_comp_i_select$Cross_R_diff_catagory<-'NA'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff < -0.002]<-'-0.025 - -0.002'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff < -0.025]<-'-0.08 - -0.025'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff < -0.08]<-'< -0.08'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > -0.002 & res_comp_i_select$Cross_R_diff < 0.002]<-'-0.002 - 0.002'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > 0.002]<-'0.002 - 0.025'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > 0.025]<-'0.025 - 0.08'
    res_comp_i_select$Cross_R_diff_catagory[res_comp_i_select$Cross_R_diff > 0.08]<-'> 0.08'
    
    res_comp_i_select$Cross_R_diff_catagory<-factor(res_comp_i_select$Cross_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
    res_comp_i_select$Indep_R_diff_catagory<-'NA'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff < -0.002]<-'-0.025 - -0.002'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff < -0.025]<-'-0.08 - -0.025'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff < -0.08]<-'< -0.08'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > -0.002 & res_comp_i_select$Indep_R_diff < 0.002]<-'-0.002 - 0.002'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > 0.002]<-'0.002 - 0.025'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > 0.025]<-'0.025 - 0.08'
    res_comp_i_select$Indep_R_diff_catagory[res_comp_i_select$Indep_R_diff > 0.08]<-'> 0.08'
    
    res_comp_i_select$Indep_R_diff_catagory<-factor(res_comp_i_select$Indep_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
    res_comp_i_select$cross_star<-' '
    res_comp_i_select$cross_star[res_comp_i_select$Cross_R_diff_pval < 0.05]<-'*'
    res_comp_i_select$cross_star[res_comp_i_select$Cross_R_diff_pval < 1e-3]<-'**'
    res_comp_i_select$cross_star[res_comp_i_select$Cross_R_diff_pval < 1e-6]<-'***'
  
    res_comp_i_select$indep_star<-' '
    res_comp_i_select$indep_star[res_comp_i_select$Indep_R_diff_pval < 0.05]<-'*'
    res_comp_i_select$indep_star[res_comp_i_select$Indep_R_diff_pval < 1e-3]<-'**'
    res_comp_i_select$indep_star[res_comp_i_select$Indep_R_diff_pval < 1e-6]<-'***'
  
    
    library(RColorBrewer)
    res_eval_diff_matrix_cross[[pheno[i]]]<-ggplot(data = res_comp_i_select, aes(Model_2_Test, Model_1_Test, fill=Cross_R_diff_catagory))+
     geom_tile(color = "white")+
     labs(y='Test', x='Comparison', title=pheno[i], fill='R difference') +
      theme_minimal()+ 
     theme(axis.text.x = element_text(angle = 45, vjust = 1, 
        size = 8, hjust = 1))+
     coord_fixed() +
    geom_text(data=res_comp_i_select, aes(Model_2_Test, Model_1_Test, label = cross_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(res_comp_i_select$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')

    res_eval_diff_matrix_indep[[pheno[i]]]<-ggplot(data = res_comp_i_select, aes(Model_2_Test, Model_1_Test, fill=Indep_R_diff_catagory))+
     geom_tile(color = "white")+
     labs(y='Test', x='Comparison', title=pheno[i], fill='R difference') +
     theme_minimal()+ 
     theme(axis.text.x = element_text(angle = 45, vjust = 1, 
     size = 8, hjust = 1))+
     coord_fixed() +
    geom_text(data=res_comp_i_select, aes(Model_2_Test, Model_1_Test, label = indep_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(res_comp_i_select$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')
  }
  
  dir.create(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/'))
  
  write.csv(res_eval, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_',Files[file],'.csv'), row.names=F, quote=F)
  
  write.csv(res_comp, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_',Files[file],'_diff.csv'), row.names=F, quote=F)
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_CrossVal_',Files[file],'.png'), units='px', res=300, width=2250, height=800*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_plots_cross, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_IndepVal_',Files[file],'.png'), units='px', res=300, width=2250, height=800*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_plots_indep, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_pTDiff_CrossVal_',Files[file],'.png'), units='px', res=300, width=2250, height=800*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_diff_plots_cross, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_pTDiff_IndepVal_',Files[file],'.png'), units='px', res=300, width=2250, height=800*ceiling(length(res_eval_plots_cross)/2))
  print(plot_grid(plotlist=res_eval_diff_plots_indep, ncol = 2))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_',Files[file],'_diff_CrossVal.png'), units='px', res=300, width=2250, height=1750*length(res_eval_diff_matrix_cross))
  print(plot_grid(plotlist=res_eval_diff_matrix_cross, ncol = 1))
  dev.off()
  
  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_',Files[file],'_diff_IndepVal.png'), units='px', res=300, width=2250, height=1750*length(res_eval_diff_matrix_cross))
  print(plot_grid(plotlist=res_eval_diff_matrix_indep, ncol = 1))
  dev.off()
  
  ###################
  # Average results across phenotypes, creates tables and figures
  ###################
  
  res_eval$Method<-gsub('\\..*','',res_eval$Test)
  res_eval$Model<-gsub('.*\\.','',res_eval$Test)
  
  res_eval$Phenotype<-factor(res_eval$Phenotype, level=unique(res_eval$Phenotype))
  res_eval$Method<-factor(res_eval$Method, level=c("pT+clump",'lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
  res_eval$Model<-factor(res_eval$Model, level=c('10FCVal','MultiPRS','PseudoVal','Inf'))
  
  res_eval<-res_eval[order(res_eval$Phenotype, res_eval$Method, res_eval$Model),]
  
  library(data.table)
  source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')
  
  if(Samples[file] == 'UKBB'){
    for(pheno_i in 1:length(pheno)){
      if(pheno_i==1){
        pheno_i_dat<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-pheno_i_dat
      } else {
        pheno_i_dat<-fread(paste0(UKBB_output,'/Phenotype/PRS_comp_subset/UKBB.',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-merge(pheno_dat, pheno_i_dat, by=c('FID','IID'), all=T)
      }
    }
  } else {
    for(pheno_i in 1:length(pheno)){
      if(pheno_i==1){
        pheno_i_dat<-fread(paste0('/users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-pheno_i_dat
      } else {
        pheno_i_dat<-fread(paste0('/users/k1806347/brc_scratch/Data/TEDS/Phenotypic/Derived_outcomes/TEDS_',pheno[pheno_i],'.txt'))
        names(pheno_i_dat)[3]<-pheno[pheno_i]
        pheno_dat<-merge(pheno_dat, pheno_i_dat, by=c('FID','IID'), all=T)
      }
    }
  }
  
  # Calculate corelation between all phenotypes
  cors<-abs(cor(as.matrix(pheno_dat[,-1:-2]), use='p'))
  cors<-cors[unique(res_eval$Phenotype,),unique(res_eval$Phenotype,)]
  cors[is.na(cors)]<-0

  # Run aggregate function
  library(MAd)
  meta_res_eval<-NULL
  for(i in unique(res_eval$Test)){
    res_eval_i<-res_eval[res_eval$Test == i,]
    res_eval_i$Sample<-'Target'
  
    CrossVal_agg_res_eval_i<-agg(id=Sample, es=CrossVal_R, var=CrossVal_R_SE^2, cor=cors, method="BHHR", mod=NULL, data=res_eval_i)
    IndepVal_agg_res_eval_i<-agg(id=Sample, es=IndepVal_R, var=IndepVal_R_SE^2, cor=cors, method="BHHR", mod=NULL, data=res_eval_i)
  
    meta_res_eval<-rbind(meta_res_eval, data.frame(  Test=i,
                                           CrossVal_R=CrossVal_agg_res_eval_i$es[1],
                                           CrossVal_R_SE=sqrt(CrossVal_agg_res_eval_i$var[1]),
                                           IndepVal_R=IndepVal_agg_res_eval_i$es[1],
                                           IndepVal_R_SE=sqrt(IndepVal_agg_res_eval_i$var[1])))
  }
  
  # Calculate difference between methods and p-value using aggregate
  # Truncate difference p-values to stop 0 values
  res_comp$Cross_R_diff_pval[res_comp$Cross_R_diff_pval == 0]<-1e-320
  res_comp$Indep_R_diff_pval[res_comp$Indep_R_diff_pval == 0]<-1e-320
  
  meta_res_diff<-NULL
  for(i in unique(res_eval$Test)){
    for(k in unique(res_eval$Test)){
      meta_res_eval_i<-meta_res_eval[meta_res_eval$Test == i,]
      meta_res_eval_k<-meta_res_eval[meta_res_eval$Test == k,]
  
      res_comp_i_k<-res_comp[res_comp$Model_1_Test == i & res_comp$Model_2_Test == k,]
      
      # Calculate diff SE based on p-value
      for(j in 1:dim(res_comp_i_k)[1]){
        if(res_comp_i_k$Cross_R_diff_pval[j] == 1){
          res_comp_i_k$Cross_R_diff_pval[j]<-1-0.001
        }
        if(res_comp_i_k$Indep_R_diff_pval[j] == 1){
          res_comp_i_k$Indep_R_diff_pval[j]<-1-0.001
        }
      }

      res_comp_i_k$Cross_R_diff_z<-qnorm(res_comp_i_k$Cross_R_diff_pval/2)
      res_comp_i_k$Cross_R_diff_SE<-res_comp_i_k$Cross_R_diff/res_comp_i_k$Cross_R_diff_z
  
      res_comp_i_k$Indep_R_diff_z<-qnorm(res_comp_i_k$Indep_R_diff_pval/2)
      res_comp_i_k$Indep_R_diff_SE<-res_comp_i_k$Indep_R_diff/res_comp_i_k$Indep_R_diff_z
      
      res_comp_i_k$Sample<-'A'
      
      CrossVal_agg_res_comp_i_k<-agg(id=Sample, es=Cross_R_diff, var=Cross_R_diff_SE^2, cor=cors, method="BHHR", mod=NULL, data=res_comp_i_k)
      
      IndepVal_agg_res_eval_i<-agg(id=Sample, es=Indep_R_diff, var=Indep_R_diff_SE^2, cor=cors, method="BHHR", mod=NULL, data=res_comp_i_k)
    
      meta_res_diff<-rbind(meta_res_diff, data.frame(Test_ref=i,
                                                     Test_targ=k,
                                                     CrossVal_R_diff=CrossVal_agg_res_comp_i_k$es[1],
                                                     CrossVal_R_diff_SE=sqrt(CrossVal_agg_res_comp_i_k$var[1]),
                                                     IndepVal_R_diff=IndepVal_agg_res_eval_i$es[1],
                                                     IndepVal_R_diff_SE=sqrt(IndepVal_agg_res_eval_i$var[1])))
    }
  }
                                           
  meta_res_diff$CrossVal_R_diff_Z<-meta_res_diff$CrossVal_R_diff/meta_res_diff$CrossVal_R_diff_SE
  meta_res_diff$CrossVal_R_diff_P<-2*pnorm(-abs(meta_res_diff$CrossVal_R_diff_Z))              
  meta_res_diff$IndepVal_R_diff_Z<-meta_res_diff$IndepVal_R_diff/meta_res_diff$IndepVal_R_diff_SE
  meta_res_diff$IndepVal_R_diff_P<-2*pnorm(-abs(meta_res_diff$IndepVal_R_diff_Z))              
  meta_res_diff<-meta_res_diff[,c("Test_ref","Test_targ","CrossVal_R_diff","CrossVal_R_diff_Z","CrossVal_R_diff_P","IndepVal_R_diff","IndepVal_R_diff_Z","IndepVal_R_diff_P")]
  
  meta_res_diff$CrossVal_R_diff_Z[meta_res_diff$CrossVal_R_diff == 0]<-0
  meta_res_diff$CrossVal_R_diff_P[meta_res_diff$CrossVal_R_diff == 0]<-1
  meta_res_diff$IndepVal_R_diff_Z[meta_res_diff$IndepVal_R_diff == 0]<-0
  meta_res_diff$IndepVal_R_diff_P[meta_res_diff$IndepVal_R_diff == 0]<-1
  
  # Calculate percentage improvement
  meta_res_diff$CrossVal_R_diff_perc<-NA
  for(i in unique(meta_res_diff$Test_ref)){
    meta_res_diff$CrossVal_R_diff_perc[meta_res_diff$Test_ref == i]<-meta_res_diff$CrossVal_R_diff[meta_res_diff$Test_ref == i]/meta_res_eval$CrossVal_R[meta_res_eval$Test == i]*100
  }
  
  meta_res_diff$IndepVal_R_diff_perc<-NA
  for(i in unique(meta_res_diff$Test_ref)){
    meta_res_diff$IndepVal_R_diff_perc[meta_res_diff$Test_ref == i]<-meta_res_diff$IndepVal_R_diff[meta_res_diff$Test_ref == i]/meta_res_eval$IndepVal_R[meta_res_eval$Test == i]*100
  }
  
  write.csv(meta_res_eval, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_',Files[file],'_meta.csv'), row.names=F, quote=F)
  
  meta_res_diff<-meta_res_diff[,c("Test_ref","Test_targ","CrossVal_R_diff",'CrossVal_R_diff_perc',"CrossVal_R_diff_Z","CrossVal_R_diff_P","IndepVal_R_diff",'IndepVal_R_diff_perc',"IndepVal_R_diff_Z","IndepVal_R_diff_P")]    
  
  write.csv(meta_res_diff, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PCresid/PRS_method_comp_',Files[file],'_diff_meta.csv'), row.names=F, quote=F)
  
  ###
  # Create plot showing performance of each method
  ###
  
    # To avoid unequal groups, insert NA for missing Model/Method pairs
  meta_res_eval$Method<-gsub('\\..*','',meta_res_eval$Test)
  meta_res_eval$Model<-gsub('.*\\.','',meta_res_eval$Test)

  meta_res_eval$Method<-factor(meta_res_eval$Method, levels=c("pT+clump",'lassosum','PRScs','SBLUP','SBayesR','LDpred1','LDpred2','DBSLMM','All'))
  meta_res_eval$Model<-factor(meta_res_eval$Model, levels=c('10FCVal','MultiPRS','PseudoVal','Inf'))

  for(i in unique(meta_res_eval$Method)){
    for(k in unique(meta_res_eval$Model)){
      if(dim(meta_res_eval[meta_res_eval$Method == i & meta_res_eval$Model == k,])[1] > 0){
        next
      } else {
        dud<-data.frame(Test=NA,
                        CrossVal_R=NA,
                        CrossVal_R_SE=NA,
                        IndepVal_R=NA,
                        IndepVal_R_SE=NA,
                        Method=i,
                        Model=k)
        meta_res_eval<-rbind(meta_res_eval,dud)
      }
    }
  }
  
  res_eval<-res_eval[,c('Phenotype','Test','CrossVal_R','IndepVal_R','Method','Model')]
  
  for(i in unique(res_eval$Method)){
    for(k in unique(res_eval$Model)){
      if(dim(res_eval[res_eval$Method == i & res_eval$Model == k,])[1] > 0){
        next
      } else {
        dud<-data.frame(Phenotype=NA,
                        Test=paste0(i,'.',k),
                        CrossVal_R=NA,
                        IndepVal_R=NA,
                        Method=i,
                        Model=k)
        res_eval<-rbind(res_eval,dud)
      }
    }
  }
  
  library(ggplot2)
  library(cowplot)
  
  meta_res_eval_plots_cross[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=CrossVal_R, fill=Model)) +
                        geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                        geom_errorbar(aes(ymin=CrossVal_R-CrossVal_R_SE, ymax=CrossVal_R+CrossVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                        labs(y="Correlation (SE)", x='', title=Files_descrip[file]) +
                        theme_half_open() +
                              theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                        background_grid(major = 'y', minor = 'y')

  meta_res_eval_plots_indep[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=IndepVal_R, fill=Model)) +
                        geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                        geom_errorbar(aes(ymin=IndepVal_R-IndepVal_R_SE, ymax=IndepVal_R+IndepVal_R_SE), width=.2, position=position_dodge(width = 0.7, preserve = "single")) +
                        labs(y="Correlation (SE)", x='', title=Files_descrip[file]) +
                        theme_half_open() +
                              theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                        background_grid(major = 'y', minor = 'y')
  
  if(Samples[file] == 'UKBB'){
    meta_res_eval_plots_cross[[Files[file]]]<-meta_res_eval_plots_cross[[Files[file]]] + coord_cartesian(ylim=c(0,0.25), clip="on")
    meta_res_eval_plots_indep[[Files[file]]]<-meta_res_eval_plots_indep[[Files[file]]] + coord_cartesian(ylim=c(0,0.25), clip="on")
  } else {
    meta_res_eval_plots_cross[[Files[file]]]<-meta_res_eval_plots_cross[[Files[file]]] + coord_cartesian(ylim=c(0,0.375), clip="on")
    meta_res_eval_plots_indep[[Files[file]]]<-meta_res_eval_plots_indep[[Files[file]]] + coord_cartesian(ylim=c(0,0.375), clip="on")
  }                           

  ###
  # Create plot showing performance of each method compared to pT+clump
  ###
  
    # Calculate differences at the average and phenotype specific level
    meta_res_eval$CrossVal_R_diff<-meta_res_eval$CrossVal_R-meta_res_eval$CrossVal_R[which(meta_res_eval$Test == "pT+clump.10FCVal")]
    
    meta_res_eval$IndepVal_R_diff<-meta_res_eval$IndepVal_R-meta_res_eval$IndepVal_R[which(meta_res_eval$Test == "pT+clump.10FCVal")]
    
    res_eval$CrossVal_R_diff<-NA
    res_eval$IndepVal_R_diff<-NA
    for(i in pheno){
        res_eval$CrossVal_R_diff[which(res_eval$Phenotype == i)]<-res_eval$CrossVal_R[which(res_eval$Phenotype == i)]-res_eval$CrossVal_R[which(res_eval$Test == "pT+clump.10FCVal" & res_eval$Phenotype == i)]
    
        res_eval$IndepVal_R_diff[which(res_eval$Phenotype == i)]<-res_eval$IndepVal_R[which(res_eval$Phenotype == i)]-res_eval$IndepVal_R[which(res_eval$Test == "pT+clump.10FCVal" & res_eval$Phenotype == i)]
    }

    meta_res_eval_diff_plots_cross[[Files[file]]] <- ggplot( meta_res_eval, aes(x=Method, y=CrossVal_R_diff, fill=Model)) +
                          geom_point(data=res_eval, mapping=aes(x=Method, y=CrossVal_R_diff, colour=Model), position=position_jitterdodge(jitter.width = 0.4, dodge.width = 1), alpha=0.3) +
                          geom_errorbar(aes(ymin=CrossVal_R_diff-CrossVal_R_SE, ymax=CrossVal_R_diff+CrossVal_R_SE), width=0.7, position=position_dodge(width = 1)) +
                          geom_point(stat="identity", position=position_dodge(1), size=2, shape=23, colour='black') +
                          labs(y="Difference in\nCorrelations (SE)", x='', title=Files_descrip[file]) +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                                  geom_vline(xintercept = 1.5, linetype="dotted") +
                                  geom_vline(xintercept = 2.5, linetype="dotted") + 
                                  geom_vline(xintercept = 3.5, linetype="dotted") + 
                                  geom_vline(xintercept = 4.5, linetype="dotted") + 
                                  geom_vline(xintercept = 5.5, linetype="dotted") +
                                  geom_vline(xintercept = 6.5, linetype="dotted") +
                                  geom_vline(xintercept = 7.5, linetype="dotted") +
                                  geom_vline(xintercept = 8.5, linetype="dotted") +
                          background_grid(major = 'y', minor = 'y') +
                          ylim(c(-0.12,0.12))
                              
    meta_res_eval_diff_plots_indep[[Files[file]]] <- ggplot(meta_res_eval, aes(x=Method, y=IndepVal_R_diff, fill=Model)) +
                          geom_point(data=res_eval, mapping=aes(x=Method, y=IndepVal_R_diff, colour=Model), position=position_jitterdodge(jitter.width = 0.4, dodge.width = 1), alpha=0.3) +
                          geom_errorbar(aes(ymin=IndepVal_R_diff-IndepVal_R_SE, ymax=IndepVal_R_diff+IndepVal_R_SE), width=0.7, position=position_dodge(width = 1)) +
                          geom_point(stat="identity", position=position_dodge(1), size=2, shape=23, colour='black') +
                          labs(y="Difference in\nCorrelations (SE)", x='', title=Files_descrip[file]) +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) + 
                                  geom_vline(xintercept = 1.5, linetype="dotted") +
                                  geom_vline(xintercept = 2.5, linetype="dotted") + 
                                  geom_vline(xintercept = 3.5, linetype="dotted") + 
                                  geom_vline(xintercept = 4.5, linetype="dotted") + 
                                  geom_vline(xintercept = 5.5, linetype="dotted") +
                                  geom_vline(xintercept = 6.5, linetype="dotted") +
                                  geom_vline(xintercept = 7.5, linetype="dotted") +
                                  geom_vline(xintercept = 8.5, linetype="dotted") +
                          background_grid(major = 'y', minor = 'y') +
                          ylim(c(-0.12,0.12))

  ###
  # Create plot showing matrix of differences with significance
  ###
  
  library(reshape2)
  
  meta_res_diff$CrossVal_R_diff[meta_res_diff$Test_ref == meta_res_diff$Test_targ]<-NA
  meta_res_diff$IndepVal_R_diff[meta_res_diff$Test_ref == meta_res_diff$Test_targ]<-NA
  
  meta_res_diff$Cross_R_diff_catagory<-'NA'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.002]<-'-0.025 - -0.002'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.025]<-'-0.08 - -0.025'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff < -0.08]<-'< -0.08'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > -0.002 & meta_res_diff$CrossVal_R_diff < 0.002]<-'-0.002 - 0.002'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.002]<-'0.002 - 0.025'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.025]<-'0.025 - 0.08'
  meta_res_diff$Cross_R_diff_catagory[meta_res_diff$CrossVal_R_diff > 0.08]<-'> 0.08'
  
  meta_res_diff$Cross_R_diff_catagory<-factor(meta_res_diff$Cross_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
  meta_res_diff$Indep_R_diff_catagory<-'NA'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.002]<-'-0.025 - -0.002'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.025]<-'-0.08 - -0.025'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff < -0.08]<-'< -0.08'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > -0.002 & meta_res_diff$IndepVal_R_diff < 0.002]<-'-0.002 - 0.002'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.002]<-'0.002 - 0.025'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.025]<-'0.025 - 0.08'
  meta_res_diff$Indep_R_diff_catagory[meta_res_diff$IndepVal_R_diff > 0.08]<-'> 0.08'
  
  meta_res_diff$Indep_R_diff_catagory<-factor(meta_res_diff$Indep_R_diff_catagory, level=rev(c('< -0.08','-0.08 - -0.025','-0.025 - -0.002','-0.002 - 0.002','0.002 - 0.025','0.025 - 0.08','> 0.08')))
  
  meta_res_diff$cross_star<-' '
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 0.05]<-'*'
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 1e-3]<-'**'
  meta_res_diff$cross_star[meta_res_diff$CrossVal_R_diff_P < 1e-6]<-'***'
  
  meta_res_diff$indep_star<-' '
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 0.05]<-'*'
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 1e-3]<-'**'
  meta_res_diff$indep_star[meta_res_diff$IndepVal_R_diff_P < 1e-6]<-'***'
  
      res_eval_diff_matrix_indep[[pheno[i]]]<-ggplot(data = res_comp_i_select, aes(Model_2_Test, Model_1_Test, fill=Indep_R_diff_catagory))+
     geom_tile(color = "white")+
     labs(y='Test', x='Comparison', title=pheno[i], fill='R difference') +
     theme_minimal()+ 
     theme(axis.text.x = element_text(angle = 45, vjust = 1, 
     size = 8, hjust = 1))+
     coord_fixed() +
    geom_text(data=res_comp_i_select, aes(Model_2_Test, Model_1_Test, label = indep_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(res_comp_i_select$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')

  library(RColorBrewer)
  meta_res_eval_diff_matrix_cross[[Files[file]]]<-ggplot(data = meta_res_diff, aes(Test_targ, Test_ref, fill=Cross_R_diff_catagory))+
   geom_tile(color = "white")+
   labs(y='Test', x='Comparison', title=Files_descrip[file], fill='R difference') +
    theme_minimal()+ 
   theme(axis.text.x = element_text(angle = 45, vjust = 1, 
      size = 8, hjust = 1)) +
   coord_fixed() +
  geom_text(data=meta_res_diff, aes(Test_ref, Test_targ, label = cross_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(meta_res_diff$Cross_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')
  
  meta_res_eval_diff_matrix_indep[[Files[file]]]<-ggplot(data = meta_res_diff, aes(Test_targ, Test_ref, fill=Indep_R_diff_catagory))+
   geom_tile(color = "white")+
   labs(y='Test', x='Comparison', title=Files_descrip[file], fill='R difference') +
    theme_minimal()+ 
   theme(axis.text.x = element_text(angle = 45, vjust = 1, 
      size = 8, hjust = 1))+
   coord_fixed() +
  geom_text(data=meta_res_diff, aes(Test_targ, Test_ref, label = indep_star), color = "black", size = 4, angle = 0, vjust=0.8) +
    scale_fill_brewer(breaks = levels(meta_res_diff$Indep_R_diff_catagory), palette = "RdBu", drop=F, na.value='grey')

}

dir.create('/scratch/users/k1806347/Analyses/PRS_comparison/PCresid')

png('/scratch/users/k1806347/Analyses/PRS_comparison/PCresid/PRS_method_comp_CrossVal_meta.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_plots_cross, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PCresid/PRS_method_comp_IndepVal_meta.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_plots_indep, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PCresid/PRS_method_comp_pTDiff_CrossVal_meta.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_diff_plots_cross, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PCresid/PRS_method_comp_pTDiff_IndepVal_meta.png', units='px', res=300, width=3200, height=1000)
plot_grid(plotlist=meta_res_eval_diff_plots_indep, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PCresid/PRS_method_comp_diff_CrossVal_meta.png', units='px', res=300, width=4000, height=2000)
plot_grid(plotlist=meta_res_eval_diff_matrix_cross, ncol = 2, nrow = 1)
dev.off()

png('/scratch/users/k1806347/Analyses/PRS_comparison/PCresid/PRS_method_comp_diff_IndepVal_meta.png', units='px', res=300, width=4000, height=2000)
plot_grid(plotlist=meta_res_eval_diff_matrix_indep, ncol = 2, nrow = 1)
dev.off()


Show AVENGEME polygenicity estimates table

Estimated polygenicity of outcomes
Phenotype GWAS HighPoly pi0_est pi0_lowCI pi0_highCI
Depression DEPR06 TRUE 0.879 0.864 0.892
Intelligence COLL01 TRUE 0.901 0.880 0.917
Height HEIG03 TRUE 0.953 0.951 0.956
BMI BODY04 TRUE 0.856 0.847 0.863
T2D DIAB05 FALSE 0.971 0.969 0.973
CAD COAD01 TRUE 0.953 0.948 0.957
IBD CROH01 FALSE 0.984 0.982 0.986
MultiScler SCLE03 FALSE 0.981 0.977 0.984
RheuArth RHEU02 FALSE 0.980 0.978 0.983
Prostate_Cancer PRCA01 FALSE 0.968 0.963 0.971
Breast_Cancer BRCA01 FALSE 0.970 0.967 0.973
Height21 HEIG03 TRUE 0.944 0.936 0.951
BMI21 BODY11 TRUE 0.843 0.817 0.866
GCSE EDUC03 TRUE 0.785 0.760 0.807
ADHD ADHD04 TRUE 0.910 0.862 0.937


4.1 1KG Reference

4.1.1 UKB

Show pT+clump method results

Correlation between PRS model predictions and observed values in UK Biobank
Phenotype Method Model CrossVal R (SE) IndepVal R (SE)
Depression pT+clump (sparse) 10FCVal 0.12 (0.005) 0.118 (0.01)
Depression pT+clump (sparse) Multi-PRS 0.127 (0.005) 0.13 (0.01)
Depression pT+clump (non-nested) 10FCVal 0.09 (0.005) 0.086 (0.01)
Depression pT+clump (non-nested) Multi-PRS 0.126 (0.005) 0.13 (0.01)
Depression pT+clump (dense) 10FCVal 0.12 (0.005) 0.117 (0.01)
Depression pT+clump (dense) Multi-PRS 0.126 (0.005) 0.13 (0.01)
Intelligence pT+clump (sparse) 10FCVal 0.084 (0.005) 0.074 (0.01)
Intelligence pT+clump (sparse) Multi-PRS 0.086 (0.005) 0.08 (0.01)
Intelligence pT+clump (non-nested) 10FCVal 0.063 (0.005) 0.059 (0.01)
Intelligence pT+clump (non-nested) Multi-PRS 0.086 (0.005) 0.078 (0.01)
Intelligence pT+clump (dense) 10FCVal 0.085 (0.005) 0.076 (0.01)
Intelligence pT+clump (dense) Multi-PRS 0.087 (0.005) 0.079 (0.01)
Height pT+clump (sparse) 10FCVal 0.304 (0.005) 0.299 (0.01)
Height pT+clump (sparse) Multi-PRS 0.32 (0.005) 0.313 (0.009)
Height pT+clump (non-nested) 10FCVal 0.26 (0.005) 0.254 (0.01)
Height pT+clump (non-nested) Multi-PRS 0.32 (0.005) 0.312 (0.01)
Height pT+clump (dense) 10FCVal 0.307 (0.005) 0.299 (0.01)
Height pT+clump (dense) Multi-PRS 0.32 (0.005) 0.313 (0.01)
BMI pT+clump (sparse) 10FCVal 0.249 (0.005) 0.244 (0.01)
BMI pT+clump (sparse) Multi-PRS 0.271 (0.005) 0.274 (0.01)
BMI pT+clump (non-nested) 10FCVal 0.184 (0.005) 0.196 (0.01)
BMI pT+clump (non-nested) Multi-PRS 0.271 (0.005) 0.274 (0.01)
BMI pT+clump (dense) 10FCVal 0.25 (0.005) 0.242 (0.01)
BMI pT+clump (dense) Multi-PRS 0.272 (0.005) 0.275 (0.01)
T2D pT+clump (sparse) 10FCVal 0.167 (0.005) 0.173 (0.01)
T2D pT+clump (sparse) Multi-PRS 0.212 (0.005) 0.215 (0.01)
T2D pT+clump (non-nested) 10FCVal 0.147 (0.005) 0.153 (0.01)
T2D pT+clump (non-nested) Multi-PRS 0.21 (0.005) 0.213 (0.01)
T2D pT+clump (dense) 10FCVal 0.168 (0.005) 0.171 (0.01)
T2D pT+clump (dense) Multi-PRS 0.211 (0.005) 0.214 (0.01)
CAD pT+clump (sparse) 10FCVal 0.135 (0.005) 0.134 (0.01)
CAD pT+clump (sparse) Multi-PRS 0.167 (0.005) 0.166 (0.01)
CAD pT+clump (non-nested) 10FCVal 0.098 (0.005) 0.099 (0.01)
CAD pT+clump (non-nested) Multi-PRS 0.167 (0.005) 0.166 (0.01)
CAD pT+clump (dense) 10FCVal 0.136 (0.005) 0.137 (0.01)
CAD pT+clump (dense) Multi-PRS 0.168 (0.005) 0.167 (0.01)
IBD pT+clump (sparse) 10FCVal 0.112 (0.005) 0.112 (0.01)
IBD pT+clump (sparse) Multi-PRS 0.128 (0.005) 0.137 (0.01)
IBD pT+clump (non-nested) 10FCVal 0.094 (0.005) 0.107 (0.01)
IBD pT+clump (non-nested) Multi-PRS 0.128 (0.005) 0.138 (0.01)
IBD pT+clump (dense) 10FCVal 0.113 (0.005) 0.117 (0.01)
IBD pT+clump (dense) Multi-PRS 0.127 (0.005) 0.136 (0.01)
MultiScler pT+clump (sparse) 10FCVal 0.09 (0.005) 0.092 (0.01)
MultiScler pT+clump (sparse) Multi-PRS 0.115 (0.005) 0.116 (0.01)
MultiScler pT+clump (non-nested) 10FCVal 0.079 (0.005) 0.075 (0.01)
MultiScler pT+clump (non-nested) Multi-PRS 0.114 (0.005) 0.116 (0.01)
MultiScler pT+clump (dense) 10FCVal 0.089 (0.005) 0.084 (0.01)
MultiScler pT+clump (dense) Multi-PRS 0.112 (0.005) 0.115 (0.01)
RheuArth pT+clump (sparse) 10FCVal 0.111 (0.005) 0.103 (0.01)
RheuArth pT+clump (sparse) Multi-PRS 0.131 (0.005) 0.124 (0.01)
RheuArth pT+clump (non-nested) 10FCVal 0.096 (0.005) 0.078 (0.01)
RheuArth pT+clump (non-nested) Multi-PRS 0.13 (0.005) 0.124 (0.01)
RheuArth pT+clump (dense) 10FCVal 0.111 (0.005) 0.103 (0.01)
RheuArth pT+clump (dense) Multi-PRS 0.132 (0.005) 0.126 (0.01)
Prostate_Cancer pT+clump (sparse) 10FCVal 0.152 (0.005) 0.166 (0.01)
Prostate_Cancer pT+clump (sparse) Multi-PRS 0.168 (0.005) 0.175 (0.01)
Prostate_Cancer pT+clump (non-nested) 10FCVal 0.138 (0.005) 0.14 (0.01)
Prostate_Cancer pT+clump (non-nested) Multi-PRS 0.169 (0.005) 0.176 (0.01)
Prostate_Cancer pT+clump (dense) 10FCVal 0.155 (0.005) 0.17 (0.01)
Prostate_Cancer pT+clump (dense) Multi-PRS 0.17 (0.005) 0.18 (0.01)
Breast_Cancer pT+clump (sparse) 10FCVal 0.179 (0.005) 0.167 (0.01)
Breast_Cancer pT+clump (sparse) Multi-PRS 0.2 (0.005) 0.188 (0.01)
Breast_Cancer pT+clump (non-nested) 10FCVal 0.168 (0.005) 0.165 (0.01)
Breast_Cancer pT+clump (non-nested) Multi-PRS 0.199 (0.005) 0.187 (0.01)
Breast_Cancer pT+clump (dense) 10FCVal 0.181 (0.005) 0.163 (0.01)
Breast_Cancer pT+clump (dense) Multi-PRS 0.198 (0.005) 0.19 (0.01)

Show cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show UKBB results table

Correlation between PRS model predictions and observed values in UK Biobank
Phenotype Method Model CrossVal_R CrossVal_R_SE CrossVal_OR CrossVal_LowCI CrossVal_HighCI Cross_LiabR2 Cross_AUC CrossVal_pval IndepVal_R IndepVal_R_SE IndepVal_OR IndepVal_LowCI IndepVal_HighCI Indep_LiabR2 Indep_AUC IndepVal_pval
Depression All MultiPRS 0.146 0.005 1.346 1.319 1.374 0.026 0.583 1.10e-188 0.146 0.010 1.348 1.295 1.404 0.026 0.582 5.97e-49
Depression DBSLMM PseudoVal 0.141 0.005 1.333 1.307 1.360 0.024 0.580 5.40e-177 0.140 0.010 1.331 1.278 1.385 0.024 0.578 4.73e-45
Depression lassosum MultiPRS 0.144 0.005 1.340 1.314 1.368 0.025 0.581 3.04e-183 0.144 0.010 1.341 1.288 1.396 0.025 0.580 2.86e-47
Depression lassosum PseudoVal 0.081 0.005 1.178 1.155 1.201 0.008 0.547 1.15e-59 0.093 0.010 1.206 1.159 1.255 0.010 0.552 1.47e-20
Depression lassosum 10FCVal 0.143 0.005 1.339 1.312 1.366 0.025 0.581 8.31e-182 0.144 0.010 1.342 1.288 1.397 0.025 0.580 1.84e-47
Depression LDpred1 MultiPRS 0.143 0.005 1.339 1.313 1.367 0.025 0.581 1.93e-182 0.139 0.010 1.328 1.276 1.383 0.023 0.578 1.63e-44
Depression LDpred1 Inf 0.143 0.005 1.340 1.313 1.367 0.025 0.581 1.22e-182 0.138 0.010 1.325 1.273 1.380 0.023 0.577 7.40e-44
Depression LDpred1 10FCVal 0.143 0.005 1.339 1.312 1.366 0.025 0.581 6.49e-182 0.140 0.010 1.331 1.279 1.386 0.024 0.579 3.41e-45
Depression LDpred2 MultiPRS 0.145 0.005 1.345 1.318 1.373 0.025 0.582 8.96e-188 0.145 0.010 1.345 1.292 1.400 0.025 0.582 2.94e-48
Depression LDpred2 10FCVal 0.146 0.005 1.346 1.319 1.374 0.026 0.582 1.56e-188 0.144 0.010 1.341 1.288 1.397 0.025 0.581 2.01e-47
Depression LDpred2 PseudoVal 0.143 0.005 1.339 1.312 1.366 0.025 0.581 4.58e-182 0.139 0.010 1.326 1.274 1.381 0.023 0.578 4.73e-44
Depression LDpred2 Inf 0.143 0.005 1.338 1.311 1.365 0.025 0.581 2.94e-181 0.139 0.010 1.326 1.274 1.381 0.023 0.577 4.98e-44
Depression PRScs MultiPRS 0.142 0.005 1.336 1.310 1.364 0.024 0.580 1.05e-179 0.141 0.010 1.334 1.282 1.389 0.024 0.579 8.04e-46
Depression PRScs 10FCVal 0.141 0.005 1.332 1.306 1.359 0.024 0.579 6.37e-176 0.139 0.010 1.329 1.276 1.383 0.023 0.578 1.27e-44
Depression PRScs PseudoVal 0.139 0.005 1.326 1.300 1.353 0.023 0.578 7.34e-171 0.139 0.010 1.326 1.274 1.381 0.023 0.579 4.89e-44
Depression pT+clump MultiPRS 0.126 0.005 1.292 1.266 1.318 0.019 0.571 1.41e-141 0.127 0.010 1.295 1.244 1.348 0.019 0.570 2.00e-37
Depression pT+clump 10FCVal 0.120 0.005 1.276 1.250 1.302 0.017 0.568 2.42e-128 0.118 0.010 1.269 1.220 1.321 0.017 0.564 3.61e-32
Depression SBayesR PseudoVal 0.113 0.005 1.256 1.231 1.282 0.015 0.564 4.36e-113 0.108 0.010 1.245 1.196 1.296 0.014 0.562 1.88e-27
Depression SBLUP Inf 0.143 0.005 1.337 1.310 1.364 0.024 0.581 1.78e-180 0.139 0.010 1.329 1.276 1.383 0.023 0.578 1.26e-44
Intelligence All MultiPRS 0.102 0.005 NA NA NA NA NA 8.80e-94 0.097 0.010 NA NA NA NA NA 1.69e-22
Intelligence DBSLMM PseudoVal 0.089 0.005 NA NA NA NA NA 1.58e-70 0.079 0.010 NA NA NA NA NA 1.71e-15
Intelligence lassosum MultiPRS 0.102 0.005 NA NA NA NA NA 3.25e-93 0.097 0.010 NA NA NA NA NA 2.78e-22
Intelligence lassosum PseudoVal 0.064 0.005 NA NA NA NA NA 2.07e-37 0.059 0.010 NA NA NA NA NA 4.55e-09
Intelligence lassosum 10FCVal 0.099 0.005 NA NA NA NA NA 1.37e-87 0.093 0.010 NA NA NA NA NA 9.43e-21
Intelligence LDpred1 MultiPRS 0.101 0.005 NA NA NA NA NA 1.10e-91 0.093 0.010 NA NA NA NA NA 1.05e-20
Intelligence LDpred1 Inf 0.100 0.005 NA NA NA NA NA 4.02e-89 0.092 0.010 NA NA NA NA NA 4.68e-20
Intelligence LDpred1 10FCVal 0.102 0.005 NA NA NA NA NA 9.61e-93 0.092 0.010 NA NA NA NA NA 2.58e-20
Intelligence LDpred2 MultiPRS 0.103 0.005 NA NA NA NA NA 6.70e-94 0.094 0.010 NA NA NA NA NA 4.14e-21
Intelligence LDpred2 10FCVal 0.103 0.005 NA NA NA NA NA 1.13e-94 0.093 0.010 NA NA NA NA NA 1.08e-20
Intelligence LDpred2 PseudoVal 0.100 0.005 NA NA NA NA NA 4.59e-90 0.093 0.010 NA NA NA NA NA 1.74e-20
Intelligence LDpred2 Inf 0.101 0.005 NA NA NA NA NA 1.99e-90 0.093 0.010 NA NA NA NA NA 1.34e-20
Intelligence PRScs MultiPRS 0.100 0.005 NA NA NA NA NA 4.92e-90 0.093 0.010 NA NA NA NA NA 1.15e-20
Intelligence PRScs 10FCVal 0.099 0.005 NA NA NA NA NA 1.64e-88 0.089 0.010 NA NA NA NA NA 3.13e-19
Intelligence PRScs PseudoVal 0.099 0.005 NA NA NA NA NA 7.97e-87 0.092 0.010 NA NA NA NA NA 2.13e-20
Intelligence pT+clump MultiPRS 0.086 0.005 NA NA NA NA NA 2.92e-67 0.080 0.010 NA NA NA NA NA 1.24e-15
Intelligence pT+clump 10FCVal 0.084 0.005 NA NA NA NA NA 2.38e-63 0.074 0.010 NA NA NA NA NA 1.32e-13
Intelligence SBayesR PseudoVal 0.072 0.005 NA NA NA NA NA 9.36e-48 0.065 0.010 NA NA NA NA NA 9.77e-11
Intelligence SBLUP Inf 0.100 0.005 NA NA NA NA NA 4.31e-90 0.092 0.010 NA NA NA NA NA 1.97e-20
Height All MultiPRS 0.358 0.005 NA NA NA NA NA 0.00e+00 0.361 0.009 NA NA NA NA NA 3.86e-305
Height DBSLMM PseudoVal 0.332 0.005 NA NA NA NA NA 0.00e+00 0.327 0.009 NA NA NA NA NA 1.77e-248
Height lassosum MultiPRS 0.350 0.005 NA NA NA NA NA 0.00e+00 0.348 0.009 NA NA NA NA NA 2.57e-283
Height lassosum 10FCVal 0.347 0.005 NA NA NA NA NA 0.00e+00 0.346 0.009 NA NA NA NA NA 1.43e-278
Height lassosum PseudoVal 0.285 0.005 NA NA NA NA NA 0.00e+00 0.281 0.010 NA NA NA NA NA 7.11e-181
Height LDpred1 MultiPRS 0.303 0.005 NA NA NA NA NA 0.00e+00 0.307 0.010 NA NA NA NA NA 6.68e-217
Height LDpred1 Inf 0.299 0.005 NA NA NA NA NA 0.00e+00 0.303 0.010 NA NA NA NA NA 4.27e-212
Height LDpred1 10FCVal 0.300 0.005 NA NA NA NA NA 0.00e+00 0.301 0.010 NA NA NA NA NA 1.31e-208
Height LDpred2 MultiPRS 0.350 0.005 NA NA NA NA NA 0.00e+00 0.354 0.009 NA NA NA NA NA 1.57e-292
Height LDpred2 10FCVal 0.343 0.005 NA NA NA NA NA 0.00e+00 0.346 0.009 NA NA NA NA NA 3.74e-279
Height LDpred2 PseudoVal 0.304 0.005 NA NA NA NA NA 0.00e+00 0.304 0.010 NA NA NA NA NA 1.33e-212
Height LDpred2 Inf 0.305 0.005 NA NA NA NA NA 0.00e+00 0.305 0.010 NA NA NA NA NA 1.41e-213
Height PRScs MultiPRS 0.347 0.005 NA NA NA NA NA 0.00e+00 0.345 0.009 NA NA NA NA NA 5.62e-278
Height PRScs 10FCVal 0.345 0.005 NA NA NA NA NA 0.00e+00 0.344 0.009 NA NA NA NA NA 1.44e-275
Height PRScs PseudoVal 0.346 0.005 NA NA NA NA NA 0.00e+00 0.344 0.009 NA NA NA NA NA 1.97e-275
Height pT+clump MultiPRS 0.320 0.005 NA NA NA NA NA 0.00e+00 0.313 0.009 NA NA NA NA NA 8.24e-226
Height pT+clump 10FCVal 0.304 0.005 NA NA NA NA NA 0.00e+00 0.299 0.010 NA NA NA NA NA 1.94e-205
Height SBayesR PseudoVal 0.344 0.005 NA NA NA NA NA 0.00e+00 0.343 0.009 NA NA NA NA NA 9.80e-275
Height SBLUP Inf 0.293 0.005 NA NA NA NA NA 0.00e+00 0.294 0.010 NA NA NA NA NA 5.63e-198
BMI All MultiPRS 0.307 0.005 NA NA NA NA NA 0.00e+00 0.305 0.010 NA NA NA NA NA 2.11e-214
BMI DBSLMM PseudoVal 0.285 0.005 NA NA NA NA NA 0.00e+00 0.283 0.010 NA NA NA NA NA 2.16e-183
BMI lassosum MultiPRS 0.305 0.005 NA NA NA NA NA 0.00e+00 0.305 0.010 NA NA NA NA NA 4.25e-214
BMI lassosum PseudoVal 0.216 0.005 NA NA NA NA NA 0.00e+00 0.225 0.010 NA NA NA NA NA 8.76e-115
BMI lassosum 10FCVal 0.300 0.005 NA NA NA NA NA 0.00e+00 0.298 0.010 NA NA NA NA NA 3.85e-204
BMI LDpred1 MultiPRS 0.289 0.005 NA NA NA NA NA 0.00e+00 0.281 0.010 NA NA NA NA NA 1.41e-180
BMI LDpred1 Inf 0.274 0.005 NA NA NA NA NA 0.00e+00 0.264 0.010 NA NA NA NA NA 9.50e-159
BMI LDpred1 10FCVal 0.279 0.005 NA NA NA NA NA 0.00e+00 0.271 0.010 NA NA NA NA NA 4.25e-168
BMI LDpred2 MultiPRS 0.302 0.005 NA NA NA NA NA 0.00e+00 0.299 0.010 NA NA NA NA NA 1.20e-205
BMI LDpred2 10FCVal 0.301 0.005 NA NA NA NA NA 0.00e+00 0.296 0.010 NA NA NA NA NA 6.63e-201
BMI LDpred2 PseudoVal 0.256 0.005 NA NA NA NA NA 0.00e+00 0.261 0.010 NA NA NA NA NA 1.56e-155
BMI LDpred2 Inf 0.291 0.005 NA NA NA NA NA 0.00e+00 0.284 0.010 NA NA NA NA NA 4.47e-185
BMI PRScs MultiPRS 0.301 0.005 NA NA NA NA NA 0.00e+00 0.296 0.010 NA NA NA NA NA 7.33e-201
BMI PRScs 10FCVal 0.292 0.005 NA NA NA NA NA 0.00e+00 0.282 0.010 NA NA NA NA NA 1.62e-181
BMI PRScs PseudoVal 0.282 0.005 NA NA NA NA NA 0.00e+00 0.282 0.010 NA NA NA NA NA 6.73e-182
BMI pT+clump MultiPRS 0.271 0.005 NA NA NA NA NA 0.00e+00 0.274 0.010 NA NA NA NA NA 2.95e-171
BMI pT+clump 10FCVal 0.249 0.005 NA NA NA NA NA 0.00e+00 0.244 0.010 NA NA NA NA NA 2.59e-135
BMI SBayesR PseudoVal 0.211 0.005 NA NA NA NA NA 0.00e+00 0.224 0.010 NA NA NA NA NA 1.09e-113
BMI SBLUP Inf 0.293 0.005 NA NA NA NA NA 0.00e+00 0.286 0.010 NA NA NA NA NA 5.09e-187
T2D All MultiPRS 0.242 0.005 1.703 1.665 1.741 0.062 0.650 0.00e+00 0.242 0.010 1.695 1.622 1.772 0.061 0.649 5.18e-133
T2D DBSLMM PseudoVal 0.229 0.005 1.656 1.619 1.693 0.055 0.642 0.00e+00 0.226 0.010 1.638 1.568 1.712 0.053 0.640 1.81e-116
T2D lassosum MultiPRS 0.237 0.005 1.687 1.650 1.725 0.059 0.647 0.00e+00 0.240 0.010 1.691 1.618 1.768 0.060 0.648 2.09e-131
T2D lassosum PseudoVal 0.206 0.005 1.567 1.533 1.602 0.044 0.627 0.00e+00 0.214 0.010 1.593 1.525 1.664 0.047 0.631 2.66e-104
T2D lassosum 10FCVal 0.214 0.005 1.599 1.564 1.634 0.048 0.632 0.00e+00 0.216 0.010 1.601 1.532 1.673 0.048 0.632 1.11e-105
T2D LDpred1 MultiPRS 0.232 0.005 1.666 1.629 1.703 0.057 0.644 0.00e+00 0.231 0.010 1.656 1.584 1.730 0.055 0.642 3.12e-121
T2D LDpred1 Inf 0.187 0.005 1.507 1.474 1.540 0.036 0.617 1.79e-311 0.184 0.010 1.493 1.430 1.559 0.035 0.615 3.26e-77
T2D LDpred1 10FCVal 0.232 0.005 1.665 1.629 1.703 0.057 0.644 0.00e+00 0.230 0.010 1.653 1.582 1.727 0.055 0.642 2.09e-120
T2D LDpred2 MultiPRS 0.242 0.005 1.704 1.666 1.742 0.062 0.650 0.00e+00 0.240 0.010 1.689 1.616 1.765 0.060 0.647 5.19e-131
T2D LDpred2 10FCVal 0.237 0.005 1.683 1.646 1.721 0.059 0.647 0.00e+00 0.238 0.010 1.680 1.608 1.756 0.059 0.646 1.30e-128
T2D LDpred2 PseudoVal 0.194 0.005 1.529 1.496 1.563 0.039 0.620 0.00e+00 0.190 0.010 1.510 1.446 1.577 0.037 0.618 1.13e-81
T2D LDpred2 Inf 0.189 0.005 1.514 1.481 1.547 0.037 0.618 1.51e-318 0.185 0.010 1.495 1.432 1.561 0.035 0.615 6.76e-78
T2D PRScs MultiPRS 0.235 0.005 1.676 1.639 1.713 0.058 0.645 0.00e+00 0.237 0.010 1.679 1.606 1.755 0.058 0.645 6.75e-128
T2D PRScs 10FCVal 0.228 0.005 1.650 1.614 1.687 0.055 0.642 0.00e+00 0.227 0.010 1.641 1.571 1.715 0.053 0.639 2.41e-117
T2D PRScs PseudoVal 0.226 0.005 1.645 1.609 1.682 0.054 0.640 0.00e+00 0.226 0.010 1.636 1.566 1.710 0.053 0.639 5.73e-116
T2D pT+clump MultiPRS 0.212 0.005 1.592 1.557 1.628 0.047 0.631 0.00e+00 0.215 0.010 1.598 1.529 1.670 0.048 0.633 6.05e-105
T2D pT+clump 10FCVal 0.167 0.005 1.440 1.409 1.472 0.029 0.604 1.44e-247 0.173 0.010 1.455 1.393 1.519 0.030 0.607 8.66e-68
T2D SBayesR PseudoVal 0.226 0.005 1.644 1.608 1.681 0.054 0.640 0.00e+00 0.227 0.010 1.641 1.570 1.714 0.053 0.640 1.97e-117
T2D SBLUP Inf 0.189 0.005 1.514 1.481 1.547 0.037 0.618 1.73e-318 0.184 0.010 1.492 1.429 1.558 0.035 0.614 4.04e-77
CAD All MultiPRS 0.191 0.005 1.485 1.454 1.516 0.027 0.609 0.00e+00 0.190 0.010 1.482 1.422 1.544 0.027 0.607 5.38e-82
CAD DBSLMM PseudoVal 0.171 0.005 1.420 1.391 1.449 0.022 0.598 1.03e-258 0.164 0.010 1.401 1.345 1.459 0.020 0.593 1.68e-61
CAD lassosum MultiPRS 0.187 0.005 1.473 1.443 1.503 0.026 0.607 1.50e-312 0.186 0.010 1.467 1.408 1.529 0.026 0.604 3.66e-78
CAD lassosum PseudoVal 0.162 0.005 1.394 1.366 1.423 0.020 0.592 6.96e-234 0.160 0.010 1.388 1.332 1.445 0.019 0.588 3.04e-58
CAD lassosum 10FCVal 0.174 0.005 1.430 1.401 1.460 0.023 0.599 5.99e-269 0.171 0.010 1.423 1.366 1.482 0.022 0.596 8.84e-67
CAD LDpred1 MultiPRS 0.173 0.005 1.428 1.399 1.457 0.022 0.599 1.24e-266 0.174 0.010 1.431 1.374 1.491 0.023 0.598 6.37e-69
CAD LDpred1 Inf 0.148 0.005 1.352 1.325 1.380 0.016 0.585 1.03e-193 0.147 0.010 1.351 1.297 1.406 0.016 0.584 1.57e-49
CAD LDpred1 10FCVal 0.172 0.005 1.425 1.396 1.454 0.022 0.598 1.83e-263 0.172 0.010 1.425 1.368 1.484 0.022 0.597 2.22e-67
CAD LDpred2 MultiPRS 0.192 0.005 1.487 1.457 1.518 0.028 0.610 0.00e+00 0.186 0.010 1.468 1.409 1.530 0.026 0.604 2.44e-78
CAD LDpred2 10FCVal 0.188 0.005 1.475 1.445 1.505 0.026 0.607 1.40e-314 0.184 0.010 1.462 1.403 1.523 0.025 0.604 8.81e-77
CAD LDpred2 PseudoVal 0.107 0.005 1.241 1.217 1.266 0.008 0.559 4.79e-102 0.111 0.010 1.252 1.203 1.303 0.009 0.561 7.84e-29
CAD LDpred2 Inf 0.162 0.005 1.394 1.366 1.422 0.019 0.593 8.28e-233 0.157 0.010 1.380 1.326 1.438 0.018 0.590 1.69e-56
CAD PRScs MultiPRS 0.186 0.005 1.469 1.439 1.499 0.026 0.607 4.20e-308 0.186 0.010 1.468 1.409 1.530 0.026 0.605 2.10e-78
CAD PRScs 10FCVal 0.181 0.005 1.454 1.424 1.484 0.025 0.604 3.86e-293 0.182 0.010 1.456 1.397 1.517 0.025 0.603 3.72e-75
CAD PRScs PseudoVal 0.181 0.005 1.453 1.423 1.483 0.024 0.603 6.93e-292 0.182 0.010 1.455 1.396 1.516 0.025 0.603 6.18e-75
CAD pT+clump MultiPRS 0.167 0.005 1.410 1.382 1.439 0.021 0.596 7.20e-249 0.166 0.010 1.407 1.351 1.466 0.021 0.593 6.59e-63
CAD pT+clump 10FCVal 0.135 0.005 1.315 1.289 1.342 0.013 0.577 5.47e-161 0.134 0.010 1.314 1.262 1.368 0.013 0.575 2.61e-41
CAD SBayesR PseudoVal 0.159 0.005 1.386 1.358 1.415 0.019 0.590 3.96e-226 0.160 0.010 1.387 1.332 1.444 0.019 0.589 4.38e-58
CAD SBLUP Inf 0.162 0.005 1.394 1.366 1.423 0.020 0.593 1.36e-233 0.157 0.010 1.379 1.325 1.437 0.018 0.590 2.87e-56
IBD All MultiPRS 0.146 0.005 1.558 1.510 1.608 0.049 0.644 3.88e-188 0.151 0.010 1.583 1.486 1.686 0.053 0.651 7.89e-52
IBD DBSLMM PseudoVal 0.131 0.005 1.503 1.457 1.552 0.039 0.632 7.13e-152 0.135 0.010 1.530 1.435 1.631 0.042 0.637 5.85e-42
IBD lassosum MultiPRS 0.142 0.005 1.546 1.498 1.595 0.047 0.641 3.20e-180 0.146 0.010 1.564 1.468 1.666 0.049 0.648 1.83e-48
IBD lassosum PseudoVal 0.134 0.005 1.518 1.471 1.567 0.041 0.634 5.40e-159 0.137 0.010 1.529 1.435 1.629 0.043 0.640 8.34e-43
IBD lassosum 10FCVal 0.134 0.005 1.519 1.471 1.567 0.042 0.632 2.71e-160 0.136 0.010 1.525 1.431 1.626 0.043 0.639 3.32e-42
IBD LDpred1 MultiPRS 0.131 0.005 1.522 1.474 1.572 0.040 0.631 2.75e-153 0.137 0.010 1.547 1.450 1.650 0.044 0.635 3.55e-43
IBD LDpred1 Inf 0.100 0.005 1.406 1.359 1.454 0.023 0.600 1.50e-89 0.104 0.010 1.425 1.332 1.525 0.025 0.603 1.30e-25
IBD LDpred1 10FCVal 0.130 0.005 1.504 1.457 1.553 0.039 0.629 8.88e-150 0.134 0.010 1.522 1.428 1.622 0.042 0.631 1.93e-41
IBD LDpred2 MultiPRS 0.143 0.005 1.553 1.505 1.602 0.047 0.643 1.28e-181 0.148 0.010 1.571 1.474 1.674 0.051 0.648 4.75e-50
IBD LDpred2 10FCVal 0.143 0.005 1.551 1.503 1.600 0.047 0.643 1.45e-181 0.145 0.010 1.557 1.461 1.659 0.049 0.647 2.49e-48
IBD LDpred2 PseudoVal 0.100 0.005 1.404 1.357 1.452 0.023 0.601 8.77e-89 0.103 0.010 1.422 1.328 1.522 0.024 0.605 5.74e-25
IBD LDpred2 Inf 0.096 0.005 1.390 1.343 1.438 0.021 0.597 1.99e-82 0.099 0.010 1.407 1.314 1.507 0.023 0.600 3.50e-23
IBD PRScs MultiPRS 0.135 0.005 1.516 1.469 1.565 0.042 0.635 1.52e-162 0.137 0.010 1.536 1.441 1.637 0.044 0.638 2.18e-43
IBD PRScs 10FCVal 0.129 0.005 1.494 1.448 1.543 0.038 0.628 2.34e-147 0.133 0.010 1.518 1.424 1.619 0.041 0.631 1.31e-40
IBD PRScs PseudoVal 0.130 0.005 1.499 1.452 1.547 0.039 0.629 1.62e-149 0.128 0.010 1.496 1.403 1.595 0.038 0.629 1.16e-37
IBD pT+clump MultiPRS 0.128 0.005 1.506 1.458 1.555 0.038 0.629 1.28e-145 0.137 0.010 1.548 1.451 1.651 0.044 0.635 3.80e-43
IBD pT+clump 10FCVal 0.112 0.005 1.449 1.401 1.498 0.029 0.616 5.73e-111 0.112 0.010 1.452 1.359 1.551 0.029 0.608 2.24e-29
IBD SBayesR PseudoVal 0.122 0.005 1.471 1.425 1.518 0.034 0.625 8.39e-133 0.130 0.010 1.499 1.407 1.597 0.039 0.637 6.55e-39
IBD SBLUP Inf 0.098 0.005 1.395 1.348 1.443 0.022 0.597 4.25e-85 0.102 0.010 1.416 1.323 1.517 0.024 0.600 2.44e-24
MultiScler All MultiPRS 0.133 0.005 1.550 1.493 1.609 0.079 0.718 1.31e-157 0.121 0.010 1.495 1.390 1.608 0.060 0.694 6.32e-34
MultiScler DBSLMM PseudoVal 0.090 0.005 1.424 1.367 1.483 0.036 0.663 1.19e-72 0.085 0.010 1.396 1.288 1.513 0.029 0.634 2.18e-17
MultiScler lassosum MultiPRS 0.126 0.005 1.542 1.484 1.603 0.070 0.708 5.35e-141 0.124 0.010 1.528 1.417 1.648 0.063 0.694 1.05e-35
MultiScler lassosum PseudoVal 0.100 0.005 1.449 1.393 1.508 0.044 0.686 1.32e-89 0.106 0.010 1.455 1.348 1.571 0.046 0.675 3.07e-26
MultiScler lassosum 10FCVal 0.115 0.005 1.530 1.468 1.594 0.059 0.673 4.31e-118 0.102 0.010 1.476 1.363 1.598 0.042 0.668 1.40e-24
MultiScler LDpred1 MultiPRS 0.103 0.005 1.510 1.448 1.575 0.047 0.674 2.92e-94 0.096 0.010 1.458 1.344 1.582 0.038 0.658 5.88e-22
MultiScler LDpred1 Inf 0.089 0.005 1.486 1.418 1.556 0.035 0.644 2.17e-70 0.081 0.010 1.440 1.315 1.578 0.026 0.630 6.95e-16
MultiScler LDpred1 10FCVal 0.103 0.005 1.484 1.424 1.546 0.047 0.677 3.61e-94 0.095 0.010 1.426 1.318 1.544 0.037 0.659 1.98e-21
MultiScler LDpred2 MultiPRS 0.130 0.005 1.562 1.504 1.622 0.075 0.712 1.45e-149 0.117 0.010 1.503 1.394 1.621 0.056 0.686 8.03e-32
MultiScler LDpred2 10FCVal 0.112 0.005 1.496 1.439 1.555 0.055 0.700 2.39e-111 0.101 0.010 1.453 1.343 1.571 0.042 0.670 4.30e-24
MultiScler LDpred2 PseudoVal 0.101 0.005 1.518 1.453 1.587 0.045 0.654 4.63e-91 0.088 0.010 1.456 1.335 1.588 0.032 0.645 1.09e-18
MultiScler LDpred2 Inf 0.092 0.005 1.501 1.434 1.571 0.037 0.641 9.98e-76 0.078 0.010 1.426 1.302 1.562 0.025 0.634 4.54e-15
MultiScler PRScs MultiPRS 0.118 0.005 1.514 1.456 1.574 0.062 0.692 2.61e-124 0.108 0.010 1.462 1.357 1.576 0.048 0.675 2.43e-27
MultiScler PRScs 10FCVal 0.118 0.005 1.536 1.474 1.600 0.061 0.675 3.97e-123 0.104 0.010 1.461 1.349 1.582 0.044 0.659 2.58e-25
MultiScler PRScs PseudoVal 0.103 0.005 1.447 1.393 1.504 0.047 0.686 7.63e-95 0.101 0.010 1.420 1.317 1.532 0.042 0.666 3.38e-24
MultiScler pT+clump MultiPRS 0.114 0.005 1.515 1.456 1.576 0.058 0.696 2.07e-116 0.116 0.010 1.513 1.400 1.635 0.055 0.677 4.31e-31
MultiScler pT+clump 10FCVal 0.090 0.005 1.444 1.385 1.507 0.036 0.665 5.26e-73 0.092 0.010 1.455 1.338 1.583 0.034 0.629 4.66e-20
MultiScler SBayesR PseudoVal 0.100 0.005 1.516 1.451 1.583 0.044 0.672 1.08e-88 0.084 0.010 1.440 1.317 1.575 0.028 0.643 4.95e-17
MultiScler SBLUP Inf 0.093 0.005 1.503 1.436 1.573 0.038 0.642 3.59e-77 0.079 0.010 1.427 1.304 1.562 0.025 0.635 2.90e-15
RheuArth All MultiPRS 0.185 0.005 1.644 1.596 1.692 0.065 0.670 2.11e-304 0.161 0.010 1.566 1.476 1.661 0.050 0.645 2.24e-59
RheuArth DBSLMM PseudoVal 0.142 0.005 1.524 1.478 1.571 0.038 0.639 6.14e-180 0.111 0.010 1.415 1.329 1.507 0.023 0.600 1.07e-28
RheuArth lassosum MultiPRS 0.183 0.005 1.627 1.581 1.675 0.064 0.669 2.97e-297 0.150 0.010 1.522 1.435 1.614 0.043 0.639 1.33e-51
RheuArth lassosum PseudoVal 0.114 0.005 1.454 1.407 1.502 0.025 0.610 1.14e-116 0.089 0.010 1.346 1.259 1.438 0.015 0.589 3.37e-19
RheuArth lassosum 10FCVal 0.162 0.005 1.560 1.516 1.607 0.050 0.654 3.05e-232 0.130 0.010 1.449 1.366 1.538 0.032 0.621 6.96e-39
RheuArth LDpred1 MultiPRS 0.145 0.005 1.544 1.497 1.592 0.040 0.640 4.70e-188 0.119 0.010 1.442 1.355 1.535 0.027 0.616 6.60e-33
RheuArth LDpred1 Inf 0.136 0.005 1.515 1.469 1.563 0.035 0.635 1.69e-165 0.111 0.010 1.415 1.328 1.507 0.023 0.611 7.94e-29
RheuArth LDpred1 10FCVal 0.136 0.005 1.517 1.470 1.565 0.035 0.634 1.96e-165 0.112 0.010 1.419 1.332 1.511 0.024 0.607 4.10e-29
RheuArth LDpred2 MultiPRS 0.151 0.005 1.587 1.538 1.638 0.043 0.644 2.66e-202 0.127 0.010 1.486 1.394 1.583 0.031 0.619 1.85e-37
RheuArth LDpred2 10FCVal 0.151 0.005 1.586 1.537 1.636 0.043 0.643 2.89e-203 0.128 0.010 1.490 1.399 1.588 0.031 0.618 5.07e-38
RheuArth LDpred2 PseudoVal 0.091 0.005 1.376 1.329 1.424 0.016 0.594 1.12e-74 0.077 0.010 1.309 1.221 1.403 0.011 0.581 1.66e-14
RheuArth LDpred2 Inf 0.085 0.005 1.353 1.307 1.401 0.014 0.588 2.55e-65 0.072 0.010 1.293 1.206 1.388 0.010 0.577 5.05e-13
RheuArth PRScs MultiPRS 0.166 0.005 1.576 1.530 1.622 0.052 0.660 5.65e-244 0.133 0.010 1.466 1.381 1.556 0.034 0.623 8.57e-41
RheuArth PRScs 10FCVal 0.161 0.005 1.547 1.503 1.593 0.049 0.657 5.26e-231 0.128 0.010 1.445 1.362 1.533 0.031 0.617 1.01e-37
RheuArth PRScs PseudoVal 0.162 0.005 1.551 1.507 1.597 0.050 0.658 1.57e-234 0.129 0.010 1.446 1.363 1.534 0.032 0.617 2.12e-38
RheuArth pT+clump MultiPRS 0.131 0.005 1.493 1.447 1.540 0.033 0.631 3.58e-153 0.124 0.010 1.466 1.377 1.562 0.029 0.623 1.28e-35
RheuArth pT+clump 10FCVal 0.111 0.005 1.425 1.380 1.471 0.023 0.614 1.72e-110 0.103 0.010 1.394 1.307 1.487 0.020 0.611 3.60e-25
RheuArth SBayesR PseudoVal 0.124 0.005 1.479 1.433 1.527 0.029 0.623 1.65e-137 0.119 0.010 1.461 1.370 1.558 0.027 0.619 6.12e-33
RheuArth SBLUP Inf 0.112 0.005 1.448 1.401 1.497 0.024 0.614 4.71e-112 0.097 0.010 1.380 1.291 1.475 0.018 0.597 3.43e-22
Prostate_Cancer All MultiPRS 0.186 0.005 1.655 1.606 1.705 0.172 0.701 2.12e-309 0.181 0.010 1.623 1.530 1.722 0.168 0.701 1.66e-74
Prostate_Cancer DBSLMM PseudoVal 0.176 0.005 1.636 1.588 1.687 0.155 0.690 5.72e-277 0.166 0.010 1.597 1.503 1.697 0.141 0.693 1.91e-62
Prostate_Cancer lassosum MultiPRS 0.187 0.005 1.683 1.633 1.735 0.173 0.699 1.66e-311 0.181 0.010 1.652 1.555 1.754 0.168 0.702 1.27e-74
Prostate_Cancer lassosum PseudoVal 0.168 0.005 1.630 1.581 1.681 0.141 0.683 6.67e-252 0.164 0.010 1.602 1.507 1.703 0.138 0.690 5.06e-61
Prostate_Cancer lassosum 10FCVal 0.180 0.005 1.654 1.605 1.705 0.161 0.693 1.67e-288 0.177 0.010 1.637 1.541 1.738 0.161 0.700 2.14e-71
Prostate_Cancer LDpred1 MultiPRS 0.164 0.005 1.620 1.570 1.671 0.135 0.679 1.64e-240 0.149 0.010 1.561 1.466 1.661 0.115 0.675 5.36e-51
Prostate_Cancer LDpred1 Inf 0.143 0.005 1.551 1.502 1.601 0.103 0.659 6.91e-182 0.133 0.010 1.525 1.429 1.627 0.092 0.655 1.04e-40
Prostate_Cancer LDpred1 10FCVal 0.165 0.005 1.605 1.557 1.656 0.136 0.680 7.46e-243 0.152 0.010 1.555 1.462 1.653 0.119 0.675 9.66e-53
Prostate_Cancer LDpred2 MultiPRS 0.183 0.005 1.677 1.626 1.729 0.166 0.699 5.37e-298 0.175 0.010 1.653 1.555 1.757 0.156 0.703 2.23e-69
Prostate_Cancer LDpred2 10FCVal 0.183 0.005 1.645 1.597 1.695 0.166 0.700 1.15e-298 0.173 0.010 1.616 1.523 1.715 0.154 0.703 3.31e-68
Prostate_Cancer LDpred2 PseudoVal 0.139 0.005 1.542 1.494 1.593 0.097 0.655 7.86e-172 0.133 0.010 1.528 1.432 1.631 0.091 0.657 1.24e-40
Prostate_Cancer LDpred2 Inf 0.135 0.005 1.532 1.483 1.583 0.092 0.651 8.62e-163 0.129 0.010 1.519 1.422 1.622 0.086 0.654 2.02e-38
Prostate_Cancer PRScs MultiPRS 0.184 0.005 1.659 1.609 1.709 0.167 0.699 5.42e-301 0.173 0.010 1.628 1.532 1.729 0.153 0.696 6.20e-68
Prostate_Cancer PRScs 10FCVal 0.181 0.005 1.637 1.589 1.687 0.162 0.696 4.74e-291 0.176 0.010 1.634 1.540 1.735 0.159 0.698 9.29e-71
Prostate_Cancer PRScs PseudoVal 0.183 0.005 1.643 1.594 1.693 0.165 0.698 9.65e-297 0.172 0.010 1.615 1.522 1.715 0.151 0.696 4.01e-67
Prostate_Cancer pT+clump MultiPRS 0.168 0.005 1.627 1.578 1.679 0.141 0.683 1.40e-251 0.175 0.010 1.640 1.542 1.744 0.156 0.691 2.85e-69
Prostate_Cancer pT+clump 10FCVal 0.152 0.005 1.587 1.538 1.638 0.116 0.669 3.61e-206 0.166 0.010 1.631 1.531 1.737 0.142 0.674 8.05e-63
Prostate_Cancer SBayesR PseudoVal 0.176 0.005 1.632 1.583 1.682 0.154 0.693 7.24e-277 0.171 0.010 1.599 1.507 1.697 0.150 0.697 1.83e-66
Prostate_Cancer SBLUP Inf 0.137 0.005 1.536 1.488 1.587 0.094 0.650 2.20e-166 0.128 0.010 1.514 1.418 1.617 0.085 0.653 7.05e-38
Breast_Cancer All MultiPRS 0.228 0.005 1.715 1.673 1.757 0.105 0.666 0.00e+00 0.215 0.010 1.655 1.577 1.736 0.090 0.654 6.31e-105
Breast_Cancer DBSLMM PseudoVal 0.217 0.005 1.681 1.640 1.722 0.096 0.660 0.00e+00 0.211 0.010 1.643 1.565 1.724 0.087 0.649 8.92e-101
Breast_Cancer lassosum MultiPRS 0.225 0.005 1.708 1.667 1.751 0.103 0.664 0.00e+00 0.212 0.010 1.646 1.568 1.727 0.088 0.653 6.68e-102
Breast_Cancer lassosum PseudoVal 0.217 0.005 1.682 1.641 1.723 0.096 0.657 0.00e+00 0.199 0.010 1.602 1.526 1.681 0.078 0.644 5.02e-90
Breast_Cancer lassosum 10FCVal 0.219 0.005 1.688 1.647 1.730 0.098 0.659 0.00e+00 0.199 0.010 1.601 1.525 1.680 0.077 0.644 7.52e-90
Breast_Cancer LDpred1 MultiPRS 0.211 0.005 1.657 1.617 1.698 0.090 0.655 0.00e+00 0.195 0.010 1.585 1.510 1.663 0.074 0.641 7.42e-86
Breast_Cancer LDpred1 Inf 0.172 0.005 1.523 1.486 1.562 0.060 0.627 2.25e-262 0.162 0.010 1.481 1.410 1.554 0.051 0.616 1.25e-59
Breast_Cancer LDpred1 10FCVal 0.201 0.005 1.621 1.582 1.662 0.082 0.647 0.00e+00 0.186 0.010 1.559 1.485 1.636 0.068 0.634 1.68e-78
Breast_Cancer LDpred2 MultiPRS 0.224 0.005 1.703 1.662 1.745 0.102 0.664 0.00e+00 0.211 0.010 1.639 1.562 1.720 0.087 0.651 1.16e-100
Breast_Cancer LDpred2 10FCVal 0.223 0.005 1.701 1.660 1.744 0.101 0.663 0.00e+00 0.211 0.010 1.642 1.565 1.724 0.087 0.650 4.71e-101
Breast_Cancer LDpred2 PseudoVal 0.169 0.005 1.514 1.477 1.552 0.058 0.625 3.86e-253 0.161 0.010 1.477 1.407 1.551 0.050 0.616 7.88e-59
Breast_Cancer LDpred2 Inf 0.168 0.005 1.510 1.474 1.548 0.057 0.625 3.29e-250 0.160 0.010 1.475 1.405 1.549 0.050 0.615 2.07e-58
Breast_Cancer PRScs MultiPRS 0.222 0.005 1.698 1.657 1.740 0.100 0.662 0.00e+00 0.210 0.010 1.641 1.564 1.723 0.087 0.651 1.59e-100
Breast_Cancer PRScs 10FCVal 0.220 0.005 1.688 1.647 1.730 0.098 0.661 0.00e+00 0.207 0.010 1.629 1.552 1.709 0.084 0.648 2.37e-97
Breast_Cancer PRScs PseudoVal 0.220 0.005 1.690 1.649 1.732 0.099 0.661 0.00e+00 0.208 0.010 1.630 1.553 1.710 0.084 0.649 7.26e-98
Breast_Cancer pT+clump MultiPRS 0.200 0.005 1.624 1.584 1.664 0.081 0.647 0.00e+00 0.188 0.010 1.564 1.490 1.641 0.069 0.636 6.73e-80
Breast_Cancer pT+clump 10FCVal 0.179 0.005 1.550 1.512 1.589 0.065 0.631 4.74e-284 0.167 0.010 1.498 1.427 1.573 0.054 0.624 1.69e-63
Breast_Cancer SBayesR PseudoVal 0.221 0.005 1.694 1.653 1.736 0.099 0.660 0.00e+00 0.205 0.010 1.619 1.543 1.699 0.082 0.648 2.51e-95
Breast_Cancer SBLUP Inf 0.168 0.005 1.510 1.473 1.548 0.057 0.624 5.33e-250 0.158 0.010 1.469 1.399 1.542 0.049 0.614 4.12e-57

Show cross-validation results compared to pT+clump

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results compared to pT+clump

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show difference results table

Difference between methods in UKBB with 1KG reference
Phenotype Model 1 Test Model 2 Test Model 1 CrossVal R Model 2 CrossVal R CrossVal R Diff CrossVal R Diff P Model 1 IndepVal R Model 2 IndepVal R IndepVal R Diff IndepVal R Diff P
Depression LDpred2.PseudoVal All.MultiPRS 0.143 0.146 -0.003 7.10e-01 0.139 0.146 -0.008 8.95e-04
Depression pT+clump.10FCVal All.MultiPRS 0.120 0.146 -0.026 2.26e-04 0.118 0.146 -0.029 3.18e-06
Depression LDpred2.MultiPRS All.MultiPRS 0.145 0.146 0.000 9.60e-01 0.145 0.146 -0.001 3.08e-01
Depression PRScs.PseudoVal All.MultiPRS 0.139 0.146 -0.007 3.09e-01 0.139 0.146 -0.008 3.26e-03
Depression LDpred1.Inf All.MultiPRS 0.143 0.146 -0.002 7.34e-01 0.138 0.146 -0.008 7.92e-04
Depression PRScs.MultiPRS All.MultiPRS 0.142 0.146 -0.004 6.15e-01 0.141 0.146 -0.005 1.65e-02
Depression LDpred2.Inf All.MultiPRS 0.143 0.146 -0.003 6.76e-01 0.139 0.146 -0.008 1.27e-03
Depression lassosum.10FCVal All.MultiPRS 0.143 0.146 -0.003 6.99e-01 0.144 0.146 -0.002 3.41e-01
Depression LDpred2.10FCVal All.MultiPRS 0.146 0.146 0.000 9.93e-01 0.144 0.146 -0.002 8.12e-02
Depression lassosum.MultiPRS All.MultiPRS 0.144 0.146 -0.002 7.62e-01 0.144 0.146 -0.003 2.23e-01
Depression LDpred1.10FCVal All.MultiPRS 0.143 0.146 -0.003 7.04e-01 0.140 0.146 -0.006 2.85e-03
Depression All.MultiPRS All.MultiPRS 0.146 0.146 0.000 1.00e+00 0.146 0.146 0.000 1.00e+00
Depression SBayesR.PseudoVal All.MultiPRS 0.113 0.146 -0.033 2.06e-06 0.108 0.146 -0.038 2.01e-08
Depression LDpred1.MultiPRS All.MultiPRS 0.143 0.146 -0.002 7.27e-01 0.139 0.146 -0.007 8.24e-04
Depression pT+clump.MultiPRS All.MultiPRS 0.126 0.146 -0.020 5.17e-03 0.127 0.146 -0.019 2.17e-04
Depression lassosum.PseudoVal All.MultiPRS 0.081 0.146 -0.064 3.26e-20 0.093 0.146 -0.054 1.13e-08
Depression PRScs.10FCVal All.MultiPRS 0.141 0.146 -0.005 4.70e-01 0.139 0.146 -0.007 1.14e-02
Depression DBSLMM.PseudoVal All.MultiPRS 0.141 0.146 -0.005 5.09e-01 0.140 0.146 -0.006 2.37e-02
Depression SBLUP.Inf All.MultiPRS 0.143 0.146 -0.003 6.44e-01 0.139 0.146 -0.007 4.76e-03
Depression SBayesR.PseudoVal DBSLMM.PseudoVal 0.113 0.141 -0.028 2.06e-15 0.108 0.140 -0.032 1.06e-05
Depression LDpred2.Inf DBSLMM.PseudoVal 0.143 0.141 0.002 2.51e-01 0.139 0.140 -0.002 5.81e-01
Depression pT+clump.10FCVal DBSLMM.PseudoVal 0.120 0.141 -0.021 1.69e-11 0.118 0.140 -0.022 3.52e-04
Depression PRScs.10FCVal DBSLMM.PseudoVal 0.141 0.141 0.000 8.09e-01 0.139 0.140 -0.001 8.48e-01
Depression PRScs.PseudoVal DBSLMM.PseudoVal 0.139 0.141 -0.002 1.47e-01 0.139 0.140 -0.002 6.40e-01
Depression pT+clump.MultiPRS DBSLMM.PseudoVal 0.126 0.141 -0.015 3.19e-02 0.127 0.140 -0.013 2.22e-02
Depression LDpred1.Inf DBSLMM.PseudoVal 0.143 0.141 0.002 1.28e-01 0.138 0.140 -0.002 5.17e-01
Depression lassosum.MultiPRS DBSLMM.PseudoVal 0.144 0.141 0.002 7.22e-01 0.144 0.140 0.004 3.13e-01
Depression LDpred2.10FCVal DBSLMM.PseudoVal 0.146 0.141 0.005 3.00e-03 0.144 0.140 0.004 2.32e-01
Depression lassosum.10FCVal DBSLMM.PseudoVal 0.143 0.141 0.002 2.83e-01 0.144 0.140 0.004 2.96e-01
Depression LDpred1.10FCVal DBSLMM.PseudoVal 0.143 0.141 0.002 1.62e-01 0.140 0.140 0.000 9.35e-01
Depression LDpred1.MultiPRS DBSLMM.PseudoVal 0.143 0.141 0.002 7.56e-01 0.139 0.140 -0.001 7.63e-01
Depression PRScs.MultiPRS DBSLMM.PseudoVal 0.142 0.141 0.001 8.77e-01 0.141 0.140 0.001 6.67e-01
Depression All.MultiPRS DBSLMM.PseudoVal 0.146 0.141 0.005 5.09e-01 0.146 0.140 0.006 2.37e-02
Depression LDpred2.PseudoVal DBSLMM.PseudoVal 0.143 0.141 0.002 1.78e-01 0.139 0.140 -0.002 5.93e-01
Depression DBSLMM.PseudoVal DBSLMM.PseudoVal 0.141 0.141 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
Depression LDpred2.MultiPRS DBSLMM.PseudoVal 0.145 0.141 0.004 5.43e-01 0.145 0.140 0.005 8.27e-02
Depression lassosum.PseudoVal DBSLMM.PseudoVal 0.081 0.141 -0.060 3.10e-35 0.093 0.140 -0.047 7.68e-07
Depression SBLUP.Inf DBSLMM.PseudoVal 0.143 0.141 0.001 3.06e-01 0.139 0.140 -0.001 8.02e-01
Depression SBayesR.PseudoVal lassosum.MultiPRS 0.113 0.144 -0.031 8.66e-06 0.108 0.144 -0.035 5.84e-07
Depression LDpred2.10FCVal lassosum.MultiPRS 0.146 0.144 0.002 7.67e-01 0.144 0.144 0.000 9.28e-01
Depression LDpred1.10FCVal lassosum.MultiPRS 0.143 0.144 -0.001 9.40e-01 0.140 0.144 -0.003 2.41e-01
Depression LDpred2.Inf lassosum.MultiPRS 0.143 0.144 -0.001 9.11e-01 0.139 0.144 -0.005 1.13e-01
Depression PRScs.10FCVal lassosum.MultiPRS 0.141 0.144 -0.003 6.77e-01 0.139 0.144 -0.004 2.01e-01
Depression PRScs.MultiPRS lassosum.MultiPRS 0.142 0.144 -0.001 2.88e-01 0.141 0.144 -0.002 3.95e-01
Depression pT+clump.MultiPRS lassosum.MultiPRS 0.126 0.144 -0.017 1.21e-02 0.127 0.144 -0.016 2.44e-03
Depression lassosum.MultiPRS lassosum.MultiPRS 0.144 0.144 0.000 1.00e+00 0.144 0.144 0.000 1.00e+00
Depression lassosum.PseudoVal lassosum.MultiPRS 0.081 0.144 -0.062 6.03e-19 0.093 0.144 -0.051 3.05e-07
Depression LDpred2.MultiPRS lassosum.MultiPRS 0.145 0.144 0.002 8.00e-01 0.145 0.144 0.002 5.81e-01
Depression LDpred1.MultiPRS lassosum.MultiPRS 0.143 0.144 0.000 9.64e-01 0.139 0.144 -0.004 1.40e-01
Depression LDpred2.PseudoVal lassosum.MultiPRS 0.143 0.144 0.000 9.47e-01 0.139 0.144 -0.005 1.05e-01
Depression LDpred1.Inf lassosum.MultiPRS 0.143 0.144 0.000 9.73e-01 0.138 0.144 -0.005 8.90e-02
Depression pT+clump.10FCVal lassosum.MultiPRS 0.120 0.144 -0.024 7.51e-04 0.118 0.144 -0.026 3.61e-05
Depression lassosum.10FCVal lassosum.MultiPRS 0.143 0.144 -0.001 9.35e-01 0.144 0.144 0.000 7.05e-01
Depression SBLUP.Inf lassosum.MultiPRS 0.143 0.144 -0.001 8.76e-01 0.139 0.144 -0.004 1.72e-01
Depression DBSLMM.PseudoVal lassosum.MultiPRS 0.141 0.144 -0.002 7.22e-01 0.140 0.144 -0.004 3.13e-01
Depression All.MultiPRS lassosum.MultiPRS 0.146 0.144 0.002 7.62e-01 0.146 0.144 0.003 2.23e-01
Depression PRScs.PseudoVal lassosum.MultiPRS 0.139 0.144 -0.005 4.78e-01 0.139 0.144 -0.005 1.11e-01
Depression LDpred1.Inf lassosum.PseudoVal 0.143 0.081 0.062 3.29e-30 0.138 0.093 0.045 2.38e-05
Depression PRScs.10FCVal lassosum.PseudoVal 0.141 0.081 0.059 5.30e-38 0.139 0.093 0.047 3.11e-07
Depression LDpred2.MultiPRS lassosum.PseudoVal 0.145 0.081 0.064 5.00e-20 0.145 0.093 0.052 3.21e-08
Depression lassosum.PseudoVal lassosum.PseudoVal 0.081 0.081 0.000 1.00e+00 0.093 0.093 0.000 1.00e+00
Depression PRScs.PseudoVal lassosum.PseudoVal 0.139 0.081 0.057 7.05e-35 0.139 0.093 0.046 6.28e-07
Depression DBSLMM.PseudoVal lassosum.PseudoVal 0.141 0.081 0.060 3.10e-35 0.140 0.093 0.047 7.68e-07
Depression SBLUP.Inf lassosum.PseudoVal 0.143 0.081 0.061 4.92e-29 0.139 0.093 0.047 1.63e-05
Depression LDpred2.Inf lassosum.PseudoVal 0.143 0.081 0.061 4.30e-29 0.139 0.093 0.046 2.66e-05
Depression pT+clump.10FCVal lassosum.PseudoVal 0.120 0.081 0.039 5.00e-11 0.118 0.093 0.025 3.46e-02
Depression LDpred2.10FCVal lassosum.PseudoVal 0.146 0.081 0.064 3.33e-39 0.144 0.093 0.051 1.38e-07
Depression lassosum.MultiPRS lassosum.PseudoVal 0.144 0.081 0.062 6.03e-19 0.144 0.093 0.051 3.05e-07
Depression LDpred1.10FCVal lassosum.PseudoVal 0.143 0.081 0.062 1.03e-31 0.140 0.093 0.048 4.83e-06
Depression All.MultiPRS lassosum.PseudoVal 0.146 0.081 0.064 3.26e-20 0.146 0.093 0.054 1.13e-08
Depression SBayesR.PseudoVal lassosum.PseudoVal 0.113 0.081 0.031 5.05e-10 0.108 0.093 0.015 1.27e-01
Depression lassosum.10FCVal lassosum.PseudoVal 0.143 0.081 0.062 8.99e-34 0.144 0.093 0.051 3.75e-07
Depression pT+clump.MultiPRS lassosum.PseudoVal 0.126 0.081 0.045 1.66e-10 0.127 0.093 0.035 9.54e-04
Depression LDpred2.PseudoVal lassosum.PseudoVal 0.143 0.081 0.062 3.09e-30 0.139 0.093 0.046 1.92e-05
Depression LDpred1.MultiPRS lassosum.PseudoVal 0.143 0.081 0.062 8.31e-19 0.139 0.093 0.047 1.06e-05
Depression PRScs.MultiPRS lassosum.PseudoVal 0.142 0.081 0.061 3.44e-18 0.141 0.093 0.049 3.36e-07
Depression lassosum.10FCVal lassosum.10FCVal 0.143 0.143 0.000 1.00e+00 0.144 0.144 0.000 1.00e+00
Depression pT+clump.MultiPRS lassosum.10FCVal 0.126 0.143 -0.017 1.54e-02 0.127 0.144 -0.017 1.67e-03
Depression LDpred2.Inf lassosum.10FCVal 0.143 0.143 0.000 9.00e-01 0.139 0.144 -0.005 1.19e-01
Depression SBayesR.PseudoVal lassosum.10FCVal 0.113 0.143 -0.030 1.92e-17 0.108 0.144 -0.036 6.11e-07
Depression PRScs.MultiPRS lassosum.10FCVal 0.142 0.143 -0.001 9.05e-01 0.141 0.144 -0.003 3.68e-01
Depression SBLUP.Inf lassosum.10FCVal 0.143 0.143 -0.001 7.47e-01 0.139 0.144 -0.004 1.76e-01
Depression lassosum.MultiPRS lassosum.10FCVal 0.144 0.143 0.001 9.35e-01 0.144 0.144 0.000 7.05e-01
Depression PRScs.10FCVal lassosum.10FCVal 0.141 0.143 -0.002 1.84e-01 0.139 0.144 -0.004 2.05e-01
Depression LDpred2.MultiPRS lassosum.10FCVal 0.145 0.143 0.002 7.38e-01 0.145 0.144 0.001 6.89e-01
Depression PRScs.PseudoVal lassosum.10FCVal 0.139 0.143 -0.004 1.00e-02 0.139 0.144 -0.005 1.16e-01
Depression LDpred2.PseudoVal lassosum.10FCVal 0.143 0.143 0.000 9.54e-01 0.139 0.144 -0.005 1.27e-01
Depression LDpred1.MultiPRS lassosum.10FCVal 0.143 0.143 0.000 9.71e-01 0.139 0.144 -0.005 1.43e-01
Depression pT+clump.10FCVal lassosum.10FCVal 0.120 0.143 -0.023 5.41e-14 0.118 0.144 -0.026 2.00e-05
Depression All.MultiPRS lassosum.10FCVal 0.146 0.143 0.003 6.99e-01 0.146 0.144 0.002 3.41e-01
Depression LDpred1.Inf lassosum.10FCVal 0.143 0.143 0.000 8.48e-01 0.138 0.144 -0.006 9.80e-02
Depression DBSLMM.PseudoVal lassosum.10FCVal 0.141 0.143 -0.002 2.83e-01 0.140 0.144 -0.004 2.96e-01
Depression LDpred1.10FCVal lassosum.10FCVal 0.143 0.143 0.000 9.77e-01 0.140 0.144 -0.004 2.29e-01
Depression lassosum.PseudoVal lassosum.10FCVal 0.081 0.143 -0.062 8.99e-34 0.093 0.144 -0.051 3.75e-07
Depression LDpred2.10FCVal lassosum.10FCVal 0.146 0.143 0.003 6.56e-02 0.144 0.144 0.000 9.83e-01
Depression LDpred2.10FCVal LDpred1.MultiPRS 0.146 0.143 0.002 7.33e-01 0.144 0.139 0.005 6.22e-02
Depression PRScs.PseudoVal LDpred1.MultiPRS 0.139 0.143 -0.005 5.05e-01 0.139 0.139 -0.001 8.22e-01
Depression LDpred2.Inf LDpred1.MultiPRS 0.143 0.143 0.000 9.47e-01 0.139 0.139 -0.001 6.79e-01
Depression pT+clump.10FCVal LDpred1.MultiPRS 0.120 0.143 -0.023 8.77e-04 0.118 0.139 -0.022 3.17e-04
Depression SBayesR.PseudoVal LDpred1.MultiPRS 0.113 0.143 -0.031 1.13e-05 0.108 0.139 -0.031 1.63e-05
Depression All.MultiPRS LDpred1.MultiPRS 0.146 0.143 0.002 7.27e-01 0.146 0.139 0.007 8.24e-04
Depression LDpred1.10FCVal LDpred1.MultiPRS 0.143 0.143 0.000 9.76e-01 0.140 0.139 0.001 2.93e-01
Depression LDpred1.MultiPRS LDpred1.MultiPRS 0.143 0.143 0.000 1.00e+00 0.139 0.139 0.000 1.00e+00
Depression PRScs.10FCVal LDpred1.MultiPRS 0.141 0.143 -0.003 7.10e-01 0.139 0.139 0.000 9.60e-01
Depression lassosum.PseudoVal LDpred1.MultiPRS 0.081 0.143 -0.062 8.31e-19 0.093 0.139 -0.047 1.06e-05
Depression pT+clump.MultiPRS LDpred1.MultiPRS 0.126 0.143 -0.017 1.46e-02 0.127 0.139 -0.012 2.81e-02
Depression LDpred1.Inf LDpred1.MultiPRS 0.143 0.143 0.000 9.91e-01 0.138 0.139 -0.001 3.78e-01
Depression lassosum.MultiPRS LDpred1.MultiPRS 0.144 0.143 0.000 9.64e-01 0.144 0.139 0.004 1.40e-01
Depression PRScs.MultiPRS LDpred1.MultiPRS 0.142 0.143 -0.001 8.77e-01 0.141 0.139 0.002 4.39e-01
Depression lassosum.10FCVal LDpred1.MultiPRS 0.143 0.143 0.000 9.71e-01 0.144 0.139 0.005 1.43e-01
Depression LDpred2.PseudoVal LDpred1.MultiPRS 0.143 0.143 0.000 9.83e-01 0.139 0.139 -0.001 6.94e-01
Depression DBSLMM.PseudoVal LDpred1.MultiPRS 0.141 0.143 -0.002 7.56e-01 0.140 0.139 0.001 7.63e-01
Depression LDpred2.MultiPRS LDpred1.MultiPRS 0.145 0.143 0.002 7.65e-01 0.145 0.139 0.006 1.41e-02
Depression SBLUP.Inf LDpred1.MultiPRS 0.143 0.143 -0.001 9.11e-01 0.139 0.139 0.000 9.04e-01
Depression All.MultiPRS LDpred1.Inf 0.146 0.143 0.002 7.34e-01 0.146 0.138 0.008 7.92e-04
Depression LDpred2.PseudoVal LDpred1.Inf 0.143 0.143 0.000 7.84e-01 0.139 0.138 0.000 8.51e-01
Depression SBayesR.PseudoVal LDpred1.Inf 0.113 0.143 -0.031 4.60e-17 0.108 0.138 -0.030 3.90e-05
Depression LDpred2.MultiPRS LDpred1.Inf 0.145 0.143 0.002 7.74e-01 0.145 0.138 0.007 7.33e-03
Depression PRScs.PseudoVal LDpred1.Inf 0.139 0.143 -0.005 9.05e-03 0.139 0.138 0.000 9.37e-01
Depression LDpred1.Inf LDpred1.Inf 0.143 0.143 0.000 1.00e+00 0.138 0.138 0.000 1.00e+00
Depression pT+clump.10FCVal LDpred1.Inf 0.120 0.143 -0.023 8.46e-15 0.118 0.138 -0.021 6.63e-04
Depression PRScs.MultiPRS LDpred1.Inf 0.142 0.143 -0.001 8.68e-01 0.141 0.138 0.003 2.89e-01
Depression lassosum.PseudoVal LDpred1.Inf 0.081 0.143 -0.062 3.29e-30 0.093 0.138 -0.045 2.38e-05
Depression pT+clump.MultiPRS LDpred1.Inf 0.126 0.143 -0.017 1.36e-02 0.127 0.138 -0.011 5.12e-02
Depression LDpred1.MultiPRS LDpred1.Inf 0.143 0.143 0.000 9.91e-01 0.139 0.138 0.001 3.78e-01
Depression PRScs.10FCVal LDpred1.Inf 0.141 0.143 -0.003 1.54e-01 0.139 0.138 0.001 7.41e-01
Depression LDpred2.Inf LDpred1.Inf 0.143 0.143 -0.001 5.23e-01 0.139 0.138 0.000 8.72e-01
Depression SBLUP.Inf LDpred1.Inf 0.143 0.143 -0.001 2.28e-01 0.139 0.138 0.001 3.88e-01
Depression DBSLMM.PseudoVal LDpred1.Inf 0.141 0.143 -0.002 1.28e-01 0.140 0.138 0.002 5.17e-01
Depression lassosum.MultiPRS LDpred1.Inf 0.144 0.143 0.000 9.73e-01 0.144 0.138 0.005 8.90e-02
Depression LDpred1.10FCVal LDpred1.Inf 0.143 0.143 0.000 7.06e-01 0.140 0.138 0.002 1.61e-01
Depression lassosum.10FCVal LDpred1.Inf 0.143 0.143 0.000 8.48e-01 0.144 0.138 0.006 9.80e-02
Depression LDpred2.10FCVal LDpred1.Inf 0.146 0.143 0.002 8.69e-02 0.144 0.138 0.006 3.66e-02
Depression LDpred1.Inf LDpred1.10FCVal 0.143 0.143 0.000 7.06e-01 0.138 0.140 -0.002 1.61e-01
Depression PRScs.MultiPRS LDpred1.10FCVal 0.142 0.143 -0.001 9.00e-01 0.141 0.140 0.001 6.91e-01
Depression LDpred1.10FCVal LDpred1.10FCVal 0.143 0.143 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
Depression All.MultiPRS LDpred1.10FCVal 0.146 0.143 0.003 7.04e-01 0.146 0.140 0.006 2.85e-03
Depression SBayesR.PseudoVal LDpred1.10FCVal 0.113 0.143 -0.030 1.31e-17 0.108 0.140 -0.032 6.28e-06
Depression DBSLMM.PseudoVal LDpred1.10FCVal 0.141 0.143 -0.002 1.62e-01 0.140 0.140 0.000 9.35e-01
Depression pT+clump.MultiPRS LDpred1.10FCVal 0.126 0.143 -0.017 1.53e-02 0.127 0.140 -0.013 1.43e-02
Depression lassosum.MultiPRS LDpred1.10FCVal 0.144 0.143 0.001 9.40e-01 0.144 0.140 0.003 2.41e-01
Depression PRScs.10FCVal LDpred1.10FCVal 0.141 0.143 -0.002 1.56e-01 0.139 0.140 -0.001 7.84e-01
Depression lassosum.10FCVal LDpred1.10FCVal 0.143 0.143 0.000 9.77e-01 0.144 0.140 0.004 2.29e-01
Depression SBLUP.Inf LDpred1.10FCVal 0.143 0.143 -0.001 4.78e-01 0.139 0.140 -0.001 5.80e-01
Depression LDpred2.PseudoVal LDpred1.10FCVal 0.143 0.143 0.000 9.52e-01 0.139 0.140 -0.002 3.64e-01
Depression pT+clump.10FCVal LDpred1.10FCVal 0.120 0.143 -0.023 1.08e-14 0.118 0.140 -0.023 1.47e-04
Depression LDpred2.MultiPRS LDpred1.10FCVal 0.145 0.143 0.002 7.42e-01 0.145 0.140 0.005 3.02e-02
Depression PRScs.PseudoVal LDpred1.10FCVal 0.139 0.143 -0.004 5.82e-03 0.139 0.140 -0.002 5.68e-01
Depression LDpred2.10FCVal LDpred1.10FCVal 0.146 0.143 0.003 1.97e-02 0.144 0.140 0.004 1.14e-01
Depression LDpred1.MultiPRS LDpred1.10FCVal 0.143 0.143 0.000 9.76e-01 0.139 0.140 -0.001 2.93e-01
Depression LDpred2.Inf LDpred1.10FCVal 0.143 0.143 0.000 7.89e-01 0.139 0.140 -0.002 3.44e-01
Depression lassosum.PseudoVal LDpred1.10FCVal 0.081 0.143 -0.062 1.03e-31 0.093 0.140 -0.048 4.83e-06
Depression LDpred1.Inf LDpred2.MultiPRS 0.143 0.145 -0.002 7.74e-01 0.138 0.145 -0.007 7.33e-03
Depression DBSLMM.PseudoVal LDpred2.MultiPRS 0.141 0.145 -0.004 5.43e-01 0.140 0.145 -0.005 8.27e-02
Depression SBLUP.Inf LDpred2.MultiPRS 0.143 0.145 -0.003 6.82e-01 0.139 0.145 -0.006 1.95e-02
Depression LDpred2.Inf LDpred2.MultiPRS 0.143 0.145 -0.003 7.15e-01 0.139 0.145 -0.007 1.84e-03
Depression pT+clump.10FCVal LDpred2.MultiPRS 0.120 0.145 -0.025 3.00e-04 0.118 0.145 -0.028 2.08e-05
Depression LDpred2.10FCVal LDpred2.MultiPRS 0.146 0.145 0.000 9.66e-01 0.144 0.145 -0.001 1.66e-01
Depression PRScs.PseudoVal LDpred2.MultiPRS 0.139 0.145 -0.007 3.35e-01 0.139 0.145 -0.007 1.84e-02
Depression LDpred1.10FCVal LDpred2.MultiPRS 0.143 0.145 -0.002 7.42e-01 0.140 0.145 -0.005 3.02e-02
Depression All.MultiPRS LDpred2.MultiPRS 0.146 0.145 0.000 9.60e-01 0.146 0.145 0.001 3.08e-01
Depression SBayesR.PseudoVal LDpred2.MultiPRS 0.113 0.145 -0.033 2.64e-06 0.108 0.145 -0.037 5.17e-08
Depression lassosum.10FCVal LDpred2.MultiPRS 0.143 0.145 -0.002 7.38e-01 0.144 0.145 -0.001 6.89e-01
Depression pT+clump.MultiPRS LDpred2.MultiPRS 0.126 0.145 -0.019 6.08e-03 0.127 0.145 -0.018 1.15e-03
Depression lassosum.MultiPRS LDpred2.MultiPRS 0.144 0.145 -0.002 8.00e-01 0.144 0.145 -0.002 5.81e-01
Depression PRScs.10FCVal LDpred2.MultiPRS 0.141 0.145 -0.005 5.03e-01 0.139 0.145 -0.006 4.69e-02
Depression PRScs.MultiPRS LDpred2.MultiPRS 0.142 0.145 -0.003 6.51e-01 0.141 0.145 -0.004 1.09e-01
Depression lassosum.PseudoVal LDpred2.MultiPRS 0.081 0.145 -0.064 5.00e-20 0.093 0.145 -0.052 3.21e-08
Depression LDpred2.PseudoVal LDpred2.MultiPRS 0.143 0.145 -0.002 7.49e-01 0.139 0.145 -0.007 1.12e-03
Depression LDpred1.MultiPRS LDpred2.MultiPRS 0.143 0.145 -0.002 7.65e-01 0.139 0.145 -0.006 1.41e-02
Depression LDpred2.MultiPRS LDpred2.MultiPRS 0.145 0.145 0.000 1.00e+00 0.145 0.145 0.000 1.00e+00
Depression LDpred1.Inf LDpred2.10FCVal 0.143 0.146 -0.002 8.69e-02 0.138 0.144 -0.006 3.66e-02
Depression PRScs.MultiPRS LDpred2.10FCVal 0.142 0.146 -0.003 6.20e-01 0.141 0.144 -0.003 2.94e-01
Depression LDpred2.MultiPRS LDpred2.10FCVal 0.145 0.146 0.000 9.66e-01 0.145 0.144 0.001 1.66e-01
Depression PRScs.PseudoVal LDpred2.10FCVal 0.139 0.146 -0.007 7.06e-07 0.139 0.144 -0.005 6.03e-02
Depression LDpred2.10FCVal LDpred2.10FCVal 0.146 0.146 0.000 1.00e+00 0.144 0.144 0.000 1.00e+00
Depression lassosum.MultiPRS LDpred2.10FCVal 0.144 0.146 -0.002 7.67e-01 0.144 0.144 0.000 9.28e-01
Depression LDpred1.10FCVal LDpred2.10FCVal 0.143 0.146 -0.003 1.97e-02 0.140 0.144 -0.004 1.14e-01
Depression All.MultiPRS LDpred2.10FCVal 0.146 0.146 0.000 9.93e-01 0.146 0.144 0.002 8.12e-02
Depression SBayesR.PseudoVal LDpred2.10FCVal 0.113 0.146 -0.033 1.84e-22 0.108 0.144 -0.036 1.34e-07
Depression DBSLMM.PseudoVal LDpred2.10FCVal 0.141 0.146 -0.005 3.00e-03 0.140 0.144 -0.004 2.32e-01
Depression pT+clump.MultiPRS LDpred2.10FCVal 0.126 0.146 -0.019 5.16e-03 0.127 0.144 -0.017 2.32e-03
Depression lassosum.PseudoVal LDpred2.10FCVal 0.081 0.146 -0.064 3.33e-39 0.093 0.144 -0.051 1.38e-07
Depression PRScs.10FCVal LDpred2.10FCVal 0.141 0.146 -0.005 7.38e-04 0.139 0.144 -0.004 1.30e-01
Depression lassosum.10FCVal LDpred2.10FCVal 0.143 0.146 -0.003 6.56e-02 0.144 0.144 0.000 9.83e-01
Depression SBLUP.Inf LDpred2.10FCVal 0.143 0.146 -0.003 1.22e-02 0.139 0.144 -0.004 8.40e-02
Depression LDpred2.PseudoVal LDpred2.10FCVal 0.143 0.146 -0.003 2.03e-02 0.139 0.144 -0.005 1.56e-02
Depression pT+clump.10FCVal LDpred2.10FCVal 0.120 0.146 -0.026 9.63e-16 0.118 0.144 -0.026 4.47e-05
Depression LDpred2.Inf LDpred2.10FCVal 0.143 0.146 -0.003 1.04e-02 0.139 0.144 -0.005 1.72e-02
Depression LDpred1.MultiPRS LDpred2.10FCVal 0.143 0.146 -0.002 7.33e-01 0.139 0.144 -0.005 6.22e-02
Depression lassosum.10FCVal LDpred2.PseudoVal 0.143 0.143 0.000 9.54e-01 0.144 0.139 0.005 1.27e-01
Depression SBLUP.Inf LDpred2.PseudoVal 0.143 0.143 -0.001 3.32e-01 0.139 0.139 0.001 4.84e-01
Depression SBayesR.PseudoVal LDpred2.PseudoVal 0.113 0.143 -0.030 3.37e-17 0.108 0.139 -0.030 2.61e-05
Depression All.MultiPRS LDpred2.PseudoVal 0.146 0.143 0.003 7.10e-01 0.146 0.139 0.008 8.95e-04
Depression PRScs.PseudoVal LDpred2.PseudoVal 0.139 0.143 -0.004 1.06e-02 0.139 0.139 0.000 9.95e-01
Depression lassosum.MultiPRS LDpred2.PseudoVal 0.144 0.143 0.000 9.47e-01 0.144 0.139 0.005 1.05e-01
Depression PRScs.MultiPRS LDpred2.PseudoVal 0.142 0.143 -0.001 8.93e-01 0.141 0.139 0.003 3.45e-01
Depression LDpred2.MultiPRS LDpred2.PseudoVal 0.145 0.143 0.002 7.49e-01 0.145 0.139 0.007 1.12e-03
Depression PRScs.10FCVal LDpred2.PseudoVal 0.141 0.143 -0.002 1.80e-01 0.139 0.139 0.001 8.00e-01
Depression LDpred2.PseudoVal LDpred2.PseudoVal 0.143 0.143 0.000 1.00e+00 0.139 0.139 0.000 1.00e+00
Depression pT+clump.MultiPRS LDpred2.PseudoVal 0.126 0.143 -0.017 1.50e-02 0.127 0.139 -0.011 5.36e-02
Depression pT+clump.10FCVal LDpred2.PseudoVal 0.120 0.143 -0.023 1.43e-13 0.118 0.139 -0.021 9.00e-04
Depression lassosum.PseudoVal LDpred2.PseudoVal 0.081 0.143 -0.062 3.09e-30 0.093 0.139 -0.046 1.92e-05
Depression LDpred1.Inf LDpred2.PseudoVal 0.143 0.143 0.000 7.84e-01 0.138 0.139 0.000 8.51e-01
Depression LDpred1.MultiPRS LDpred2.PseudoVal 0.143 0.143 0.000 9.83e-01 0.139 0.139 0.001 6.94e-01
Depression LDpred1.10FCVal LDpred2.PseudoVal 0.143 0.143 0.000 9.52e-01 0.140 0.139 0.002 3.64e-01
Depression LDpred2.Inf LDpred2.PseudoVal 0.143 0.143 0.000 4.41e-01 0.139 0.139 0.000 9.66e-01
Depression LDpred2.10FCVal LDpred2.PseudoVal 0.146 0.143 0.003 2.03e-02 0.144 0.139 0.005 1.56e-02
Depression DBSLMM.PseudoVal LDpred2.PseudoVal 0.141 0.143 -0.002 1.78e-01 0.140 0.139 0.002 5.93e-01
Depression pT+clump.MultiPRS LDpred2.Inf 0.126 0.143 -0.017 1.69e-02 0.127 0.139 -0.011 4.98e-02
Depression lassosum.MultiPRS LDpred2.Inf 0.144 0.143 0.001 9.11e-01 0.144 0.139 0.005 1.13e-01
Depression SBayesR.PseudoVal LDpred2.Inf 0.113 0.143 -0.030 1.40e-16 0.108 0.139 -0.030 3.32e-05
Depression All.MultiPRS LDpred2.Inf 0.146 0.143 0.003 6.76e-01 0.146 0.139 0.008 1.27e-03
Depression SBLUP.Inf LDpred2.Inf 0.143 0.143 0.000 6.23e-01 0.139 0.139 0.001 4.52e-01
Depression LDpred2.PseudoVal LDpred2.Inf 0.143 0.143 0.000 4.41e-01 0.139 0.139 0.000 9.66e-01
Depression PRScs.MultiPRS LDpred2.Inf 0.142 0.143 -0.001 9.30e-01 0.141 0.139 0.003 3.50e-01
Depression LDpred2.MultiPRS LDpred2.Inf 0.145 0.143 0.003 7.15e-01 0.145 0.139 0.007 1.84e-03
Depression PRScs.10FCVal LDpred2.Inf 0.141 0.143 -0.002 2.71e-01 0.139 0.139 0.001 8.04e-01
Depression LDpred1.Inf LDpred2.Inf 0.143 0.143 0.001 5.23e-01 0.138 0.139 0.000 8.72e-01
Depression LDpred1.MultiPRS LDpred2.Inf 0.143 0.143 0.000 9.47e-01 0.139 0.139 0.001 6.79e-01
Depression pT+clump.10FCVal LDpred2.Inf 0.120 0.143 -0.023 5.47e-14 0.118 0.139 -0.021 6.17e-04
Depression lassosum.PseudoVal LDpred2.Inf 0.081 0.143 -0.061 4.30e-29 0.093 0.139 -0.046 2.66e-05
Depression PRScs.PseudoVal LDpred2.Inf 0.139 0.143 -0.004 2.44e-02 0.139 0.139 0.000 9.97e-01
Depression DBSLMM.PseudoVal LDpred2.Inf 0.141 0.143 -0.002 2.51e-01 0.140 0.139 0.002 5.81e-01
Depression LDpred1.10FCVal LDpred2.Inf 0.143 0.143 0.000 7.89e-01 0.140 0.139 0.002 3.44e-01
Depression LDpred2.Inf LDpred2.Inf 0.143 0.143 0.000 1.00e+00 0.139 0.139 0.000 1.00e+00
Depression lassosum.10FCVal LDpred2.Inf 0.143 0.143 0.000 9.00e-01 0.144 0.139 0.005 1.19e-01
Depression LDpred2.10FCVal LDpred2.Inf 0.146 0.143 0.003 1.04e-02 0.144 0.139 0.005 1.72e-02
Depression PRScs.10FCVal PRScs.MultiPRS 0.141 0.142 -0.002 8.29e-01 0.139 0.141 -0.002 1.62e-01
Depression LDpred1.10FCVal PRScs.MultiPRS 0.143 0.142 0.001 9.00e-01 0.140 0.141 -0.001 6.91e-01
Depression lassosum.MultiPRS PRScs.MultiPRS 0.144 0.142 0.001 2.88e-01 0.144 0.141 0.002 3.95e-01
Depression LDpred2.MultiPRS PRScs.MultiPRS 0.145 0.142 0.003 6.51e-01 0.145 0.141 0.004 1.09e-01
Depression All.MultiPRS PRScs.MultiPRS 0.146 0.142 0.004 6.15e-01 0.146 0.141 0.005 1.65e-02
Depression PRScs.PseudoVal PRScs.MultiPRS 0.139 0.142 -0.004 6.10e-01 0.139 0.141 -0.003 2.31e-01
Depression LDpred1.MultiPRS PRScs.MultiPRS 0.143 0.142 0.001 8.77e-01 0.139 0.141 -0.002 4.39e-01
Depression pT+clump.MultiPRS PRScs.MultiPRS 0.126 0.142 -0.016 2.10e-02 0.127 0.141 -0.014 7.98e-03
Depression lassosum.PseudoVal PRScs.MultiPRS 0.081 0.142 -0.061 3.44e-18 0.093 0.141 -0.049 3.36e-07
Depression SBayesR.PseudoVal PRScs.MultiPRS 0.113 0.142 -0.030 2.16e-05 0.108 0.141 -0.033 1.95e-06
Depression DBSLMM.PseudoVal PRScs.MultiPRS 0.141 0.142 -0.001 8.77e-01 0.140 0.141 -0.001 6.67e-01
Depression SBLUP.Inf PRScs.MultiPRS 0.143 0.142 0.000 9.65e-01 0.139 0.141 -0.002 5.00e-01
Depression LDpred2.Inf PRScs.MultiPRS 0.143 0.142 0.001 9.30e-01 0.139 0.141 -0.003 3.50e-01
Depression pT+clump.10FCVal PRScs.MultiPRS 0.120 0.142 -0.022 1.52e-03 0.118 0.141 -0.024 1.65e-04
Depression LDpred2.10FCVal PRScs.MultiPRS 0.146 0.142 0.003 6.20e-01 0.144 0.141 0.003 2.94e-01
Depression lassosum.10FCVal PRScs.MultiPRS 0.143 0.142 0.001 9.05e-01 0.144 0.141 0.003 3.68e-01
Depression LDpred2.PseudoVal PRScs.MultiPRS 0.143 0.142 0.001 8.93e-01 0.139 0.141 -0.003 3.45e-01
Depression LDpred1.Inf PRScs.MultiPRS 0.143 0.142 0.001 8.68e-01 0.138 0.141 -0.003 2.89e-01
Depression PRScs.MultiPRS PRScs.MultiPRS 0.142 0.142 0.000 1.00e+00 0.141 0.141 0.000 1.00e+00
Depression LDpred2.PseudoVal PRScs.10FCVal 0.143 0.141 0.002 1.80e-01 0.139 0.139 -0.001 8.00e-01
Depression PRScs.10FCVal PRScs.10FCVal 0.141 0.141 0.000 1.00e+00 0.139 0.139 0.000 1.00e+00
Depression LDpred2.MultiPRS PRScs.10FCVal 0.145 0.141 0.005 5.03e-01 0.145 0.139 0.006 4.69e-02
Depression pT+clump.MultiPRS PRScs.10FCVal 0.126 0.141 -0.015 3.71e-02 0.127 0.139 -0.012 3.68e-02
Depression LDpred1.Inf PRScs.10FCVal 0.143 0.141 0.003 1.54e-01 0.138 0.139 -0.001 7.41e-01
Depression LDpred1.MultiPRS PRScs.10FCVal 0.143 0.141 0.003 7.10e-01 0.139 0.139 0.000 9.60e-01
Depression pT+clump.10FCVal PRScs.10FCVal 0.120 0.141 -0.021 2.06e-09 0.118 0.139 -0.022 1.64e-03
Depression lassosum.PseudoVal PRScs.10FCVal 0.081 0.141 -0.059 5.30e-38 0.093 0.139 -0.047 3.11e-07
Depression PRScs.PseudoVal PRScs.10FCVal 0.139 0.141 -0.002 1.70e-01 0.139 0.139 -0.001 7.49e-01
Depression DBSLMM.PseudoVal PRScs.10FCVal 0.141 0.141 0.000 8.09e-01 0.140 0.139 0.001 8.48e-01
Depression SBLUP.Inf PRScs.10FCVal 0.143 0.141 0.002 3.23e-01 0.139 0.139 0.000 9.98e-01
Depression LDpred2.Inf PRScs.10FCVal 0.143 0.141 0.002 2.71e-01 0.139 0.139 -0.001 8.04e-01
Depression lassosum.10FCVal PRScs.10FCVal 0.143 0.141 0.002 1.84e-01 0.144 0.139 0.004 2.05e-01
Depression LDpred2.10FCVal PRScs.10FCVal 0.146 0.141 0.005 7.38e-04 0.144 0.139 0.004 1.30e-01
Depression lassosum.MultiPRS PRScs.10FCVal 0.144 0.141 0.003 6.77e-01 0.144 0.139 0.004 2.01e-01
Depression LDpred1.10FCVal PRScs.10FCVal 0.143 0.141 0.002 1.56e-01 0.140 0.139 0.001 7.84e-01
Depression All.MultiPRS PRScs.10FCVal 0.146 0.141 0.005 4.70e-01 0.146 0.139 0.007 1.14e-02
Depression SBayesR.PseudoVal PRScs.10FCVal 0.113 0.141 -0.028 9.79e-16 0.108 0.139 -0.031 8.48e-06
Depression PRScs.MultiPRS PRScs.10FCVal 0.142 0.141 0.002 8.29e-01 0.141 0.139 0.002 1.62e-01
Depression All.MultiPRS PRScs.PseudoVal 0.146 0.139 0.007 3.09e-01 0.146 0.139 0.008 3.26e-03
Depression pT+clump.MultiPRS PRScs.PseudoVal 0.126 0.139 -0.012 7.30e-02 0.127 0.139 -0.011 5.35e-02
Depression LDpred2.PseudoVal PRScs.PseudoVal 0.143 0.139 0.004 1.06e-02 0.139 0.139 0.000 9.95e-01
Depression SBayesR.PseudoVal PRScs.PseudoVal 0.113 0.139 -0.026 6.07e-14 0.108 0.139 -0.030 1.56e-05
Depression LDpred2.MultiPRS PRScs.PseudoVal 0.145 0.139 0.007 3.35e-01 0.145 0.139 0.007 1.84e-02
Depression SBLUP.Inf PRScs.PseudoVal 0.143 0.139 0.004 2.82e-02 0.139 0.139 0.001 7.91e-01
Depression LDpred1.Inf PRScs.PseudoVal 0.143 0.139 0.005 9.05e-03 0.138 0.139 0.000 9.37e-01
Depression PRScs.10FCVal PRScs.PseudoVal 0.141 0.139 0.002 1.70e-01 0.139 0.139 0.001 7.49e-01
Depression LDpred2.Inf PRScs.PseudoVal 0.143 0.139 0.004 2.44e-02 0.139 0.139 0.000 9.97e-01
Depression PRScs.PseudoVal PRScs.PseudoVal 0.139 0.139 0.000 1.00e+00 0.139 0.139 0.000 1.00e+00
Depression LDpred2.10FCVal PRScs.PseudoVal 0.146 0.139 0.007 7.06e-07 0.144 0.139 0.005 6.03e-02
Depression pT+clump.10FCVal PRScs.PseudoVal 0.120 0.139 -0.019 4.41e-08 0.118 0.139 -0.021 2.43e-03
Depression PRScs.MultiPRS PRScs.PseudoVal 0.142 0.139 0.004 6.10e-01 0.141 0.139 0.003 2.31e-01
Depression lassosum.PseudoVal PRScs.PseudoVal 0.081 0.139 -0.057 7.05e-35 0.093 0.139 -0.046 6.28e-07
Depression lassosum.10FCVal PRScs.PseudoVal 0.143 0.139 0.004 1.00e-02 0.144 0.139 0.005 1.16e-01
Depression LDpred1.MultiPRS PRScs.PseudoVal 0.143 0.139 0.005 5.05e-01 0.139 0.139 0.001 8.22e-01
Depression lassosum.MultiPRS PRScs.PseudoVal 0.144 0.139 0.005 4.78e-01 0.144 0.139 0.005 1.11e-01
Depression LDpred1.10FCVal PRScs.PseudoVal 0.143 0.139 0.004 5.82e-03 0.140 0.139 0.002 5.68e-01
Depression DBSLMM.PseudoVal PRScs.PseudoVal 0.141 0.139 0.002 1.47e-01 0.140 0.139 0.002 6.40e-01
Depression All.MultiPRS pT+clump.MultiPRS 0.146 0.126 0.020 5.17e-03 0.146 0.127 0.019 2.17e-04
Depression SBayesR.PseudoVal pT+clump.MultiPRS 0.113 0.126 -0.014 5.29e-02 0.108 0.127 -0.019 1.76e-02
Depression LDpred1.MultiPRS pT+clump.MultiPRS 0.143 0.126 0.017 1.46e-02 0.139 0.127 0.012 2.81e-02
Depression pT+clump.MultiPRS pT+clump.MultiPRS 0.126 0.126 0.000 1.00e+00 0.127 0.127 0.000 1.00e+00
Depression lassosum.PseudoVal pT+clump.MultiPRS 0.081 0.126 -0.045 1.66e-10 0.093 0.127 -0.035 9.54e-04
Depression PRScs.10FCVal pT+clump.MultiPRS 0.141 0.126 0.015 3.71e-02 0.139 0.127 0.012 3.68e-02
Depression DBSLMM.PseudoVal pT+clump.MultiPRS 0.141 0.126 0.015 3.19e-02 0.140 0.127 0.013 2.22e-02
Depression SBLUP.Inf pT+clump.MultiPRS 0.143 0.126 0.016 1.91e-02 0.139 0.127 0.012 2.72e-02
Depression LDpred2.Inf pT+clump.MultiPRS 0.143 0.126 0.017 1.69e-02 0.139 0.127 0.011 4.98e-02
Depression pT+clump.10FCVal pT+clump.MultiPRS 0.120 0.126 -0.006 3.84e-01 0.118 0.127 -0.010 3.27e-04
Depression LDpred2.10FCVal pT+clump.MultiPRS 0.146 0.126 0.019 5.16e-03 0.144 0.127 0.017 2.32e-03
Depression PRScs.PseudoVal pT+clump.MultiPRS 0.139 0.126 0.012 7.30e-02 0.139 0.127 0.011 5.35e-02
Depression LDpred1.10FCVal pT+clump.MultiPRS 0.143 0.126 0.017 1.53e-02 0.140 0.127 0.013 1.43e-02
Depression LDpred1.Inf pT+clump.MultiPRS 0.143 0.126 0.017 1.36e-02 0.138 0.127 0.011 5.12e-02
Depression PRScs.MultiPRS pT+clump.MultiPRS 0.142 0.126 0.016 2.10e-02 0.141 0.127 0.014 7.98e-03
Depression lassosum.10FCVal pT+clump.MultiPRS 0.143 0.126 0.017 1.54e-02 0.144 0.127 0.017 1.67e-03
Depression LDpred2.PseudoVal pT+clump.MultiPRS 0.143 0.126 0.017 1.50e-02 0.139 0.127 0.011 5.36e-02
Depression lassosum.MultiPRS pT+clump.MultiPRS 0.144 0.126 0.017 1.21e-02 0.144 0.127 0.016 2.44e-03
Depression LDpred2.MultiPRS pT+clump.MultiPRS 0.145 0.126 0.019 6.08e-03 0.145 0.127 0.018 1.15e-03
Depression LDpred2.10FCVal pT+clump.10FCVal 0.146 0.120 0.026 9.63e-16 0.144 0.118 0.026 4.47e-05
Depression pT+clump.MultiPRS pT+clump.10FCVal 0.126 0.120 0.006 3.84e-01 0.127 0.118 0.010 3.27e-04
Depression LDpred2.Inf pT+clump.10FCVal 0.143 0.120 0.023 5.47e-14 0.139 0.118 0.021 6.17e-04
Depression SBayesR.PseudoVal pT+clump.10FCVal 0.113 0.120 -0.007 9.07e-02 0.108 0.118 -0.009 2.85e-01
Depression PRScs.MultiPRS pT+clump.10FCVal 0.142 0.120 0.022 1.52e-03 0.141 0.118 0.024 1.65e-04
Depression SBLUP.Inf pT+clump.10FCVal 0.143 0.120 0.022 2.11e-14 0.139 0.118 0.022 2.20e-04
Depression lassosum.MultiPRS pT+clump.10FCVal 0.144 0.120 0.024 7.51e-04 0.144 0.118 0.026 3.61e-05
Depression PRScs.10FCVal pT+clump.10FCVal 0.141 0.120 0.021 2.06e-09 0.139 0.118 0.022 1.64e-03
Depression LDpred2.MultiPRS pT+clump.10FCVal 0.145 0.120 0.025 3.00e-04 0.145 0.118 0.028 2.08e-05
Depression lassosum.10FCVal pT+clump.10FCVal 0.143 0.120 0.023 5.41e-14 0.144 0.118 0.026 2.00e-05
Depression LDpred2.PseudoVal pT+clump.10FCVal 0.143 0.120 0.023 1.43e-13 0.139 0.118 0.021 9.00e-04
Depression LDpred1.MultiPRS pT+clump.10FCVal 0.143 0.120 0.023 8.77e-04 0.139 0.118 0.022 3.17e-04
Depression pT+clump.10FCVal pT+clump.10FCVal 0.120 0.120 0.000 1.00e+00 0.118 0.118 0.000 1.00e+00
Depression All.MultiPRS pT+clump.10FCVal 0.146 0.120 0.026 2.26e-04 0.146 0.118 0.029 3.18e-06
Depression LDpred1.Inf pT+clump.10FCVal 0.143 0.120 0.023 8.46e-15 0.138 0.118 0.021 6.63e-04
Depression DBSLMM.PseudoVal pT+clump.10FCVal 0.141 0.120 0.021 1.69e-11 0.140 0.118 0.022 3.52e-04
Depression LDpred1.10FCVal pT+clump.10FCVal 0.143 0.120 0.023 1.08e-14 0.140 0.118 0.023 1.47e-04
Depression lassosum.PseudoVal pT+clump.10FCVal 0.081 0.120 -0.039 5.00e-11 0.093 0.118 -0.025 3.46e-02
Depression PRScs.PseudoVal pT+clump.10FCVal 0.139 0.120 0.019 4.41e-08 0.139 0.118 0.021 2.43e-03
Depression pT+clump.MultiPRS SBayesR.PseudoVal 0.126 0.113 0.014 5.29e-02 0.127 0.108 0.019 1.76e-02
Depression LDpred1.10FCVal SBayesR.PseudoVal 0.143 0.113 0.030 1.31e-17 0.140 0.108 0.032 6.28e-06
Depression PRScs.10FCVal SBayesR.PseudoVal 0.141 0.113 0.028 9.79e-16 0.139 0.108 0.031 8.48e-06
Depression LDpred2.10FCVal SBayesR.PseudoVal 0.146 0.113 0.033 1.84e-22 0.144 0.108 0.036 1.34e-07
Depression lassosum.10FCVal SBayesR.PseudoVal 0.143 0.113 0.030 1.92e-17 0.144 0.108 0.036 6.11e-07
Depression LDpred2.PseudoVal SBayesR.PseudoVal 0.143 0.113 0.030 3.37e-17 0.139 0.108 0.030 2.61e-05
Depression lassosum.MultiPRS SBayesR.PseudoVal 0.144 0.113 0.031 8.66e-06 0.144 0.108 0.035 5.84e-07
Depression LDpred2.MultiPRS SBayesR.PseudoVal 0.145 0.113 0.033 2.64e-06 0.145 0.108 0.037 5.17e-08
Depression All.MultiPRS SBayesR.PseudoVal 0.146 0.113 0.033 2.06e-06 0.146 0.108 0.038 2.01e-08
Depression PRScs.PseudoVal SBayesR.PseudoVal 0.139 0.113 0.026 6.07e-14 0.139 0.108 0.030 1.56e-05
Depression LDpred1.MultiPRS SBayesR.PseudoVal 0.143 0.113 0.031 1.13e-05 0.139 0.108 0.031 1.63e-05
Depression pT+clump.10FCVal SBayesR.PseudoVal 0.120 0.113 0.007 9.07e-02 0.118 0.108 0.009 2.85e-01
Depression lassosum.PseudoVal SBayesR.PseudoVal 0.081 0.113 -0.031 5.05e-10 0.093 0.108 -0.015 1.27e-01
Depression SBayesR.PseudoVal SBayesR.PseudoVal 0.113 0.113 0.000 1.00e+00 0.108 0.108 0.000 1.00e+00
Depression DBSLMM.PseudoVal SBayesR.PseudoVal 0.141 0.113 0.028 2.06e-15 0.140 0.108 0.032 1.06e-05
Depression SBLUP.Inf SBayesR.PseudoVal 0.143 0.113 0.030 2.11e-16 0.139 0.108 0.031 1.70e-05
Depression LDpred2.Inf SBayesR.PseudoVal 0.143 0.113 0.030 1.40e-16 0.139 0.108 0.030 3.32e-05
Depression LDpred1.Inf SBayesR.PseudoVal 0.143 0.113 0.031 4.60e-17 0.138 0.108 0.030 3.90e-05
Depression PRScs.MultiPRS SBayesR.PseudoVal 0.142 0.113 0.030 2.16e-05 0.141 0.108 0.033 1.95e-06
Depression LDpred2.10FCVal SBLUP.Inf 0.146 0.143 0.003 1.22e-02 0.144 0.139 0.004 8.40e-02
Depression PRScs.PseudoVal SBLUP.Inf 0.139 0.143 -0.004 2.82e-02 0.139 0.139 -0.001 7.91e-01
Depression LDpred1.10FCVal SBLUP.Inf 0.143 0.143 0.001 4.78e-01 0.140 0.139 0.001 5.80e-01
Depression LDpred2.Inf SBLUP.Inf 0.143 0.143 0.000 6.23e-01 0.139 0.139 -0.001 4.52e-01
Depression SBayesR.PseudoVal SBLUP.Inf 0.113 0.143 -0.030 2.11e-16 0.108 0.139 -0.031 1.70e-05
Depression lassosum.10FCVal SBLUP.Inf 0.143 0.143 0.001 7.47e-01 0.144 0.139 0.004 1.76e-01
Depression pT+clump.MultiPRS SBLUP.Inf 0.126 0.143 -0.016 1.91e-02 0.127 0.139 -0.012 2.72e-02
Depression lassosum.MultiPRS SBLUP.Inf 0.144 0.143 0.001 8.76e-01 0.144 0.139 0.004 1.72e-01
Depression PRScs.10FCVal SBLUP.Inf 0.141 0.143 -0.002 3.23e-01 0.139 0.139 0.000 9.98e-01
Depression PRScs.MultiPRS SBLUP.Inf 0.142 0.143 0.000 9.65e-01 0.141 0.139 0.002 5.00e-01
Depression LDpred1.MultiPRS SBLUP.Inf 0.143 0.143 0.001 9.11e-01 0.139 0.139 0.000 9.04e-01
Depression LDpred2.PseudoVal SBLUP.Inf 0.143 0.143 0.001 3.32e-01 0.139 0.139 -0.001 4.84e-01
Depression LDpred1.Inf SBLUP.Inf 0.143 0.143 0.001 2.28e-01 0.138 0.139 -0.001 3.88e-01
Depression LDpred2.MultiPRS SBLUP.Inf 0.145 0.143 0.003 6.82e-01 0.145 0.139 0.006 1.95e-02
Depression All.MultiPRS SBLUP.Inf 0.146 0.143 0.003 6.44e-01 0.146 0.139 0.007 4.76e-03
Depression SBLUP.Inf SBLUP.Inf 0.143 0.143 0.000 1.00e+00 0.139 0.139 0.000 1.00e+00
Depression DBSLMM.PseudoVal SBLUP.Inf 0.141 0.143 -0.001 3.06e-01 0.140 0.139 0.001 8.02e-01
Depression pT+clump.10FCVal SBLUP.Inf 0.120 0.143 -0.022 2.11e-14 0.118 0.139 -0.022 2.20e-04
Depression lassosum.PseudoVal SBLUP.Inf 0.081 0.143 -0.061 4.92e-29 0.093 0.139 -0.047 1.63e-05
Intelligence LDpred2.PseudoVal All.MultiPRS 0.100 0.102 -0.002 7.68e-01 0.093 0.097 -0.005 1.16e-01
Intelligence pT+clump.10FCVal All.MultiPRS 0.084 0.102 -0.019 8.46e-03 0.074 0.097 -0.023 2.37e-04
Intelligence LDpred2.MultiPRS All.MultiPRS 0.103 0.102 0.000 9.48e-01 0.094 0.097 -0.003 8.12e-02
Intelligence PRScs.PseudoVal All.MultiPRS 0.099 0.102 -0.004 5.78e-01 0.092 0.097 -0.005 1.50e-01
Intelligence LDpred1.Inf All.MultiPRS 0.100 0.102 -0.003 7.11e-01 0.092 0.097 -0.006 7.11e-02
Intelligence PRScs.MultiPRS All.MultiPRS 0.100 0.102 -0.002 1.57e-01 0.093 0.097 -0.004 1.30e-01
Intelligence LDpred2.Inf All.MultiPRS 0.101 0.102 -0.002 7.90e-01 0.093 0.097 -0.005 1.38e-01
Intelligence lassosum.10FCVal All.MultiPRS 0.099 0.102 -0.003 6.21e-01 0.093 0.097 -0.004 2.43e-01
Intelligence LDpred2.10FCVal All.MultiPRS 0.103 0.102 0.000 9.44e-01 0.093 0.097 -0.004 6.03e-02
Intelligence lassosum.MultiPRS All.MultiPRS 0.102 0.102 0.000 7.70e-01 0.097 0.097 -0.001 8.06e-01
Intelligence LDpred1.10FCVal All.MultiPRS 0.102 0.102 -0.001 9.35e-01 0.092 0.097 -0.005 5.55e-02
Intelligence All.MultiPRS All.MultiPRS 0.102 0.102 0.000 1.00e+00 0.097 0.097 0.000 1.00e+00
Intelligence SBayesR.PseudoVal All.MultiPRS 0.072 0.102 -0.030 2.15e-05 0.065 0.097 -0.033 4.97e-05
Intelligence LDpred1.MultiPRS All.MultiPRS 0.101 0.102 -0.001 8.67e-01 0.093 0.097 -0.004 1.06e-01
Intelligence pT+clump.MultiPRS All.MultiPRS 0.086 0.102 -0.016 2.29e-02 0.080 0.097 -0.017 2.02e-03
Intelligence lassosum.PseudoVal All.MultiPRS 0.064 0.102 -0.039 4.97e-08 0.059 0.097 -0.039 4.72e-06
Intelligence PRScs.10FCVal All.MultiPRS 0.099 0.102 -0.003 6.74e-01 0.089 0.097 -0.008 2.28e-02
Intelligence DBSLMM.PseudoVal All.MultiPRS 0.089 0.102 -0.014 4.94e-02 0.079 0.097 -0.018 3.11e-04
Intelligence SBLUP.Inf All.MultiPRS 0.100 0.102 -0.002 7.70e-01 0.092 0.097 -0.005 1.09e-01
Intelligence SBayesR.PseudoVal DBSLMM.PseudoVal 0.072 0.089 -0.016 2.04e-04 0.065 0.079 -0.015 9.17e-02
Intelligence LDpred2.Inf DBSLMM.PseudoVal 0.101 0.089 0.012 1.80e-06 0.093 0.079 0.013 7.09e-03
Intelligence pT+clump.10FCVal DBSLMM.PseudoVal 0.084 0.089 -0.005 2.18e-01 0.074 0.079 -0.006 4.62e-01
Intelligence PRScs.10FCVal DBSLMM.PseudoVal 0.099 0.089 0.011 3.01e-05 0.089 0.079 0.010 5.47e-02
Intelligence PRScs.PseudoVal DBSLMM.PseudoVal 0.099 0.089 0.010 1.36e-04 0.092 0.079 0.013 1.24e-02
Intelligence pT+clump.MultiPRS DBSLMM.PseudoVal 0.086 0.089 -0.002 7.63e-01 0.080 0.079 0.000 9.54e-01
Intelligence LDpred1.Inf DBSLMM.PseudoVal 0.100 0.089 0.011 1.74e-05 0.092 0.079 0.012 1.96e-02
Intelligence lassosum.MultiPRS DBSLMM.PseudoVal 0.102 0.089 0.014 5.47e-02 0.097 0.079 0.017 4.05e-04
Intelligence LDpred2.10FCVal DBSLMM.PseudoVal 0.103 0.089 0.014 4.46e-10 0.093 0.079 0.014 3.02e-03
Intelligence lassosum.10FCVal DBSLMM.PseudoVal 0.099 0.089 0.010 3.00e-04 0.093 0.079 0.014 1.49e-02
Intelligence LDpred1.10FCVal DBSLMM.PseudoVal 0.102 0.089 0.013 1.23e-07 0.092 0.079 0.013 1.10e-02
Intelligence LDpred1.MultiPRS DBSLMM.PseudoVal 0.101 0.089 0.013 7.18e-02 0.093 0.079 0.014 6.95e-03
Intelligence PRScs.MultiPRS DBSLMM.PseudoVal 0.100 0.089 0.012 9.48e-02 0.093 0.079 0.014 4.48e-03
Intelligence All.MultiPRS DBSLMM.PseudoVal 0.102 0.089 0.014 4.94e-02 0.097 0.079 0.018 3.11e-04
Intelligence LDpred2.PseudoVal DBSLMM.PseudoVal 0.100 0.089 0.012 2.25e-06 0.093 0.079 0.013 7.90e-03
Intelligence DBSLMM.PseudoVal DBSLMM.PseudoVal 0.089 0.089 0.000 1.00e+00 0.079 0.079 0.000 1.00e+00
Intelligence LDpred2.MultiPRS DBSLMM.PseudoVal 0.103 0.089 0.014 4.81e-02 0.094 0.079 0.015 1.08e-03
Intelligence lassosum.PseudoVal DBSLMM.PseudoVal 0.064 0.089 -0.025 5.98e-08 0.059 0.079 -0.021 2.21e-02
Intelligence SBLUP.Inf DBSLMM.PseudoVal 0.100 0.089 0.012 2.24e-06 0.092 0.079 0.013 8.58e-03
Intelligence SBayesR.PseudoVal lassosum.MultiPRS 0.072 0.102 -0.030 2.60e-05 0.065 0.097 -0.032 1.03e-04
Intelligence LDpred2.10FCVal lassosum.MultiPRS 0.103 0.102 0.001 9.09e-01 0.093 0.097 -0.004 1.08e-01
Intelligence LDpred1.10FCVal lassosum.MultiPRS 0.102 0.102 0.000 9.70e-01 0.092 0.097 -0.005 1.22e-01
Intelligence LDpred2.Inf lassosum.MultiPRS 0.101 0.102 -0.002 8.25e-01 0.093 0.097 -0.004 2.08e-01
Intelligence PRScs.10FCVal lassosum.MultiPRS 0.099 0.102 -0.003 7.07e-01 0.089 0.097 -0.007 3.31e-02
Intelligence PRScs.MultiPRS lassosum.MultiPRS 0.100 0.102 -0.002 2.11e-01 0.093 0.097 -0.004 1.71e-01
Intelligence pT+clump.MultiPRS lassosum.MultiPRS 0.086 0.102 -0.016 2.57e-02 0.080 0.097 -0.017 4.08e-03
Intelligence lassosum.MultiPRS lassosum.MultiPRS 0.102 0.102 0.000 1.00e+00 0.097 0.097 0.000 1.00e+00
Intelligence lassosum.PseudoVal lassosum.MultiPRS 0.064 0.102 -0.038 6.16e-08 0.059 0.097 -0.038 4.70e-06
Intelligence LDpred2.MultiPRS lassosum.MultiPRS 0.103 0.102 0.000 7.65e-01 0.094 0.097 -0.003 2.60e-01
Intelligence LDpred1.MultiPRS lassosum.MultiPRS 0.101 0.102 -0.001 9.03e-01 0.093 0.097 -0.004 2.38e-01
Intelligence LDpred2.PseudoVal lassosum.MultiPRS 0.100 0.102 -0.002 8.02e-01 0.093 0.097 -0.004 1.72e-01
Intelligence LDpred1.Inf lassosum.MultiPRS 0.100 0.102 -0.002 7.44e-01 0.092 0.097 -0.005 1.32e-01
Intelligence pT+clump.10FCVal lassosum.MultiPRS 0.084 0.102 -0.018 9.58e-03 0.074 0.097 -0.023 5.90e-04
Intelligence lassosum.10FCVal lassosum.MultiPRS 0.099 0.102 -0.003 6.52e-01 0.093 0.097 -0.004 2.04e-01
Intelligence SBLUP.Inf lassosum.MultiPRS 0.100 0.102 -0.002 8.04e-01 0.092 0.097 -0.004 1.66e-01
Intelligence DBSLMM.PseudoVal lassosum.MultiPRS 0.089 0.102 -0.014 5.47e-02 0.079 0.097 -0.017 4.05e-04
Intelligence All.MultiPRS lassosum.MultiPRS 0.102 0.102 0.000 7.70e-01 0.097 0.097 0.001 8.06e-01
Intelligence PRScs.PseudoVal lassosum.MultiPRS 0.099 0.102 -0.004 6.08e-01 0.092 0.097 -0.004 1.92e-01
Intelligence LDpred1.Inf lassosum.PseudoVal 0.100 0.064 0.036 3.63e-13 0.092 0.059 0.033 7.86e-04
Intelligence PRScs.10FCVal lassosum.PseudoVal 0.099 0.064 0.036 3.55e-17 0.089 0.059 0.031 2.19e-04
Intelligence LDpred2.MultiPRS lassosum.PseudoVal 0.103 0.064 0.039 4.56e-08 0.094 0.059 0.036 2.02e-05
Intelligence lassosum.PseudoVal lassosum.PseudoVal 0.064 0.064 0.000 1.00e+00 0.059 0.059 0.000 1.00e+00
Intelligence PRScs.PseudoVal lassosum.PseudoVal 0.099 0.064 0.035 2.40e-16 0.092 0.059 0.034 5.12e-05
Intelligence DBSLMM.PseudoVal lassosum.PseudoVal 0.089 0.064 0.025 5.98e-08 0.079 0.059 0.021 2.21e-02
Intelligence SBLUP.Inf lassosum.PseudoVal 0.100 0.064 0.037 1.05e-13 0.092 0.059 0.034 5.20e-04
Intelligence LDpred2.Inf lassosum.PseudoVal 0.101 0.064 0.037 8.04e-14 0.093 0.059 0.034 4.46e-04
Intelligence pT+clump.10FCVal lassosum.PseudoVal 0.084 0.064 0.020 1.39e-04 0.074 0.059 0.015 1.38e-01
Intelligence LDpred2.10FCVal lassosum.PseudoVal 0.103 0.064 0.039 5.06e-21 0.093 0.059 0.034 2.88e-05
Intelligence lassosum.MultiPRS lassosum.PseudoVal 0.102 0.064 0.038 6.16e-08 0.097 0.059 0.038 4.70e-06
Intelligence LDpred1.10FCVal lassosum.PseudoVal 0.102 0.064 0.038 2.66e-18 0.092 0.059 0.034 9.94e-05
Intelligence All.MultiPRS lassosum.PseudoVal 0.102 0.064 0.039 4.97e-08 0.097 0.059 0.039 4.72e-06
Intelligence SBayesR.PseudoVal lassosum.PseudoVal 0.072 0.064 0.009 7.99e-02 0.065 0.059 0.006 5.42e-01
Intelligence lassosum.10FCVal lassosum.PseudoVal 0.099 0.064 0.035 1.97e-15 0.093 0.059 0.035 7.70e-05
Intelligence pT+clump.MultiPRS lassosum.PseudoVal 0.086 0.064 0.023 1.32e-03 0.080 0.059 0.021 1.36e-02
Intelligence LDpred2.PseudoVal lassosum.PseudoVal 0.100 0.064 0.037 7.66e-14 0.093 0.059 0.034 4.57e-04
Intelligence LDpred1.MultiPRS lassosum.PseudoVal 0.101 0.064 0.037 1.11e-07 0.093 0.059 0.035 1.04e-04
Intelligence PRScs.MultiPRS lassosum.PseudoVal 0.100 0.064 0.037 2.41e-07 0.093 0.059 0.034 2.23e-05
Intelligence lassosum.10FCVal lassosum.10FCVal 0.099 0.099 0.000 1.00e+00 0.093 0.093 0.000 1.00e+00
Intelligence pT+clump.MultiPRS lassosum.10FCVal 0.086 0.099 -0.012 7.55e-02 0.080 0.093 -0.013 1.31e-02
Intelligence LDpred2.Inf lassosum.10FCVal 0.101 0.099 0.002 3.76e-01 0.093 0.093 0.000 9.17e-01
Intelligence SBayesR.PseudoVal lassosum.10FCVal 0.072 0.099 -0.026 1.78e-10 0.065 0.093 -0.029 6.09e-04
Intelligence PRScs.MultiPRS lassosum.10FCVal 0.100 0.099 0.001 8.43e-01 0.093 0.093 0.000 9.49e-01
Intelligence SBLUP.Inf lassosum.10FCVal 0.100 0.099 0.001 4.26e-01 0.092 0.093 -0.001 8.23e-01
Intelligence lassosum.MultiPRS lassosum.10FCVal 0.102 0.099 0.003 6.52e-01 0.097 0.093 0.004 2.04e-01
Intelligence PRScs.10FCVal lassosum.10FCVal 0.099 0.099 0.001 7.79e-01 0.089 0.093 -0.004 3.10e-01
Intelligence LDpred2.MultiPRS lassosum.10FCVal 0.103 0.099 0.004 6.14e-01 0.094 0.093 0.001 8.00e-01
Intelligence PRScs.PseudoVal lassosum.10FCVal 0.099 0.099 0.000 8.12e-01 0.092 0.093 -0.001 8.14e-01
Intelligence LDpred2.PseudoVal lassosum.10FCVal 0.100 0.099 0.001 4.70e-01 0.093 0.093 -0.001 8.65e-01
Intelligence LDpred1.MultiPRS lassosum.10FCVal 0.101 0.099 0.002 7.41e-01 0.093 0.093 0.000 9.73e-01
Intelligence pT+clump.10FCVal lassosum.10FCVal 0.084 0.099 -0.015 3.72e-07 0.074 0.093 -0.019 9.65e-04
Intelligence All.MultiPRS lassosum.10FCVal 0.102 0.099 0.003 6.21e-01 0.097 0.093 0.004 2.43e-01
Intelligence LDpred1.Inf lassosum.10FCVal 0.100 0.099 0.001 6.51e-01 0.092 0.093 -0.002 6.54e-01
Intelligence DBSLMM.PseudoVal lassosum.10FCVal 0.089 0.099 -0.010 3.00e-04 0.079 0.093 -0.014 1.49e-02
Intelligence LDpred1.10FCVal lassosum.10FCVal 0.102 0.099 0.003 7.14e-02 0.092 0.093 -0.001 7.39e-01
Intelligence lassosum.PseudoVal lassosum.10FCVal 0.064 0.099 -0.035 1.97e-15 0.059 0.093 -0.035 7.70e-05
Intelligence LDpred2.10FCVal lassosum.10FCVal 0.103 0.099 0.004 1.72e-02 0.093 0.093 0.000 9.64e-01
Intelligence LDpred2.10FCVal LDpred1.MultiPRS 0.103 0.101 0.002 8.13e-01 0.093 0.093 0.000 9.88e-01
Intelligence PRScs.PseudoVal LDpred1.MultiPRS 0.099 0.101 -0.003 6.95e-01 0.092 0.093 -0.001 8.15e-01
Intelligence LDpred2.Inf LDpred1.MultiPRS 0.101 0.101 -0.001 9.20e-01 0.093 0.093 0.000 9.15e-01
Intelligence pT+clump.10FCVal LDpred1.MultiPRS 0.084 0.101 -0.017 1.33e-02 0.074 0.093 -0.019 2.30e-03
Intelligence SBayesR.PseudoVal LDpred1.MultiPRS 0.072 0.101 -0.029 4.38e-05 0.065 0.093 -0.028 6.61e-04
Intelligence All.MultiPRS LDpred1.MultiPRS 0.102 0.101 0.001 8.67e-01 0.097 0.093 0.004 1.06e-01
Intelligence LDpred1.10FCVal LDpred1.MultiPRS 0.102 0.101 0.001 9.33e-01 0.092 0.093 -0.001 3.50e-01
Intelligence LDpred1.MultiPRS LDpred1.MultiPRS 0.101 0.101 0.000 1.00e+00 0.093 0.093 0.000 1.00e+00
Intelligence PRScs.10FCVal LDpred1.MultiPRS 0.099 0.101 -0.002 7.98e-01 0.089 0.093 -0.004 2.64e-01
Intelligence lassosum.PseudoVal LDpred1.MultiPRS 0.064 0.101 -0.037 1.11e-07 0.059 0.093 -0.035 1.04e-04
Intelligence pT+clump.MultiPRS LDpred1.MultiPRS 0.086 0.101 -0.015 3.55e-02 0.080 0.093 -0.013 2.26e-02
Intelligence LDpred1.Inf LDpred1.MultiPRS 0.100 0.101 -0.001 8.37e-01 0.092 0.093 -0.002 3.78e-01
Intelligence lassosum.MultiPRS LDpred1.MultiPRS 0.102 0.101 0.001 9.03e-01 0.097 0.093 0.004 2.38e-01
Intelligence PRScs.MultiPRS LDpred1.MultiPRS 0.100 0.101 -0.001 8.94e-01 0.093 0.093 0.000 9.73e-01
Intelligence lassosum.10FCVal LDpred1.MultiPRS 0.099 0.101 -0.002 7.41e-01 0.093 0.093 0.000 9.73e-01
Intelligence LDpred2.PseudoVal LDpred1.MultiPRS 0.100 0.101 -0.001 8.97e-01 0.093 0.093 -0.001 8.30e-01
Intelligence DBSLMM.PseudoVal LDpred1.MultiPRS 0.089 0.101 -0.013 7.18e-02 0.079 0.093 -0.014 6.95e-03
Intelligence LDpred2.MultiPRS LDpred1.MultiPRS 0.103 0.101 0.001 8.60e-01 0.094 0.093 0.001 6.99e-01
Intelligence SBLUP.Inf LDpred1.MultiPRS 0.100 0.101 -0.001 8.99e-01 0.092 0.093 -0.001 7.78e-01
Intelligence All.MultiPRS LDpred1.Inf 0.102 0.100 0.003 7.11e-01 0.097 0.092 0.006 7.11e-02
Intelligence LDpred2.PseudoVal LDpred1.Inf 0.100 0.100 0.001 5.80e-01 0.093 0.092 0.001 5.73e-01
Intelligence SBayesR.PseudoVal LDpred1.Inf 0.072 0.100 -0.027 1.56e-10 0.065 0.092 -0.027 1.78e-03
Intelligence LDpred2.MultiPRS LDpred1.Inf 0.103 0.100 0.003 7.04e-01 0.094 0.092 0.003 3.89e-01
Intelligence PRScs.PseudoVal LDpred1.Inf 0.099 0.100 -0.001 4.73e-01 0.092 0.092 0.001 8.18e-01
Intelligence LDpred1.Inf LDpred1.Inf 0.100 0.100 0.000 1.00e+00 0.092 0.092 0.000 1.00e+00
Intelligence pT+clump.10FCVal LDpred1.Inf 0.084 0.100 -0.016 4.03e-07 0.074 0.092 -0.018 4.50e-03
Intelligence PRScs.MultiPRS LDpred1.Inf 0.100 0.100 0.001 9.41e-01 0.093 0.092 0.001 6.49e-01
Intelligence lassosum.PseudoVal LDpred1.Inf 0.064 0.100 -0.036 3.63e-13 0.059 0.092 -0.033 7.86e-04
Intelligence pT+clump.MultiPRS LDpred1.Inf 0.086 0.100 -0.013 5.75e-02 0.080 0.092 -0.012 5.65e-02
Intelligence LDpred1.MultiPRS LDpred1.Inf 0.101 0.100 0.001 8.37e-01 0.093 0.092 0.002 3.78e-01
Intelligence PRScs.10FCVal LDpred1.Inf 0.099 0.100 0.000 8.53e-01 0.089 0.092 -0.002 5.80e-01
Intelligence LDpred2.Inf LDpred1.Inf 0.101 0.100 0.001 4.16e-01 0.093 0.092 0.001 4.56e-01
Intelligence SBLUP.Inf LDpred1.Inf 0.100 0.100 0.001 5.31e-01 0.092 0.092 0.001 5.93e-01
Intelligence DBSLMM.PseudoVal LDpred1.Inf 0.089 0.100 -0.011 1.74e-05 0.079 0.092 -0.012 1.96e-02
Intelligence lassosum.MultiPRS LDpred1.Inf 0.102 0.100 0.002 7.44e-01 0.097 0.092 0.005 1.32e-01
Intelligence LDpred1.10FCVal LDpred1.Inf 0.102 0.100 0.002 4.39e-02 0.092 0.092 0.001 7.49e-01
Intelligence lassosum.10FCVal LDpred1.Inf 0.099 0.100 -0.001 6.51e-01 0.093 0.092 0.002 6.54e-01
Intelligence LDpred2.10FCVal LDpred1.Inf 0.103 0.100 0.003 3.29e-02 0.093 0.092 0.002 5.88e-01
Intelligence LDpred1.Inf LDpred1.10FCVal 0.100 0.102 -0.002 4.39e-02 0.092 0.092 -0.001 7.49e-01
Intelligence PRScs.MultiPRS LDpred1.10FCVal 0.100 0.102 -0.002 8.29e-01 0.093 0.092 0.001 7.35e-01
Intelligence LDpred1.10FCVal LDpred1.10FCVal 0.102 0.102 0.000 1.00e+00 0.092 0.092 0.000 1.00e+00
Intelligence All.MultiPRS LDpred1.10FCVal 0.102 0.102 0.001 9.35e-01 0.097 0.092 0.005 5.55e-02
Intelligence SBayesR.PseudoVal LDpred1.10FCVal 0.072 0.102 -0.029 6.95e-13 0.065 0.092 -0.028 8.80e-04
Intelligence DBSLMM.PseudoVal LDpred1.10FCVal 0.089 0.102 -0.013 1.23e-07 0.079 0.092 -0.013 1.10e-02
Intelligence pT+clump.MultiPRS LDpred1.10FCVal 0.086 0.102 -0.015 2.86e-02 0.080 0.092 -0.012 3.14e-02
Intelligence lassosum.MultiPRS LDpred1.10FCVal 0.102 0.102 0.000 9.70e-01 0.097 0.092 0.005 1.22e-01
Intelligence PRScs.10FCVal LDpred1.10FCVal 0.099 0.102 -0.002 1.28e-01 0.089 0.092 -0.003 3.87e-01
Intelligence lassosum.10FCVal LDpred1.10FCVal 0.099 0.102 -0.003 7.14e-02 0.093 0.092 0.001 7.39e-01
Intelligence SBLUP.Inf LDpred1.10FCVal 0.100 0.102 -0.001 2.40e-01 0.092 0.092 0.000 9.10e-01
Intelligence LDpred2.PseudoVal LDpred1.10FCVal 0.100 0.102 -0.002 2.60e-01 0.093 0.092 0.000 8.74e-01
Intelligence pT+clump.10FCVal LDpred1.10FCVal 0.084 0.102 -0.018 2.02e-08 0.074 0.092 -0.018 3.88e-03
Intelligence LDpred2.MultiPRS LDpred1.10FCVal 0.103 0.102 0.001 9.27e-01 0.094 0.092 0.002 4.14e-01
Intelligence PRScs.PseudoVal LDpred1.10FCVal 0.099 0.102 -0.003 2.86e-02 0.092 0.092 0.000 9.47e-01
Intelligence LDpred2.10FCVal LDpred1.10FCVal 0.103 0.102 0.001 3.13e-01 0.093 0.092 0.001 6.60e-01
Intelligence LDpred1.MultiPRS LDpred1.10FCVal 0.101 0.102 -0.001 9.33e-01 0.093 0.092 0.001 3.50e-01
Intelligence LDpred2.Inf LDpred1.10FCVal 0.101 0.102 -0.001 3.17e-01 0.093 0.092 0.001 7.87e-01
Intelligence lassosum.PseudoVal LDpred1.10FCVal 0.064 0.102 -0.038 2.66e-18 0.059 0.092 -0.034 9.94e-05
Intelligence LDpred1.Inf LDpred2.MultiPRS 0.100 0.103 -0.003 7.04e-01 0.092 0.094 -0.003 3.89e-01
Intelligence DBSLMM.PseudoVal LDpred2.MultiPRS 0.089 0.103 -0.014 4.81e-02 0.079 0.094 -0.015 1.08e-03
Intelligence SBLUP.Inf LDpred2.MultiPRS 0.100 0.103 -0.002 7.62e-01 0.092 0.094 -0.002 5.15e-01
Intelligence LDpred2.Inf LDpred2.MultiPRS 0.101 0.103 -0.002 7.83e-01 0.093 0.094 -0.001 6.09e-01
Intelligence pT+clump.10FCVal LDpred2.MultiPRS 0.084 0.103 -0.019 8.16e-03 0.074 0.094 -0.020 2.14e-03
Intelligence LDpred2.10FCVal LDpred2.MultiPRS 0.103 0.103 0.000 9.52e-01 0.093 0.094 -0.001 4.31e-01
Intelligence PRScs.PseudoVal LDpred2.MultiPRS 0.099 0.103 -0.004 5.71e-01 0.092 0.094 -0.002 5.69e-01
Intelligence LDpred1.10FCVal LDpred2.MultiPRS 0.102 0.103 -0.001 9.27e-01 0.092 0.094 -0.002 4.14e-01
Intelligence All.MultiPRS LDpred2.MultiPRS 0.102 0.103 0.000 9.48e-01 0.097 0.094 0.003 8.12e-02
Intelligence SBayesR.PseudoVal LDpred2.MultiPRS 0.072 0.103 -0.030 2.02e-05 0.065 0.094 -0.029 2.94e-04
Intelligence lassosum.10FCVal LDpred2.MultiPRS 0.099 0.103 -0.004 6.14e-01 0.093 0.094 -0.001 8.00e-01
Intelligence pT+clump.MultiPRS LDpred2.MultiPRS 0.086 0.103 -0.016 2.23e-02 0.080 0.094 -0.014 1.34e-02
Intelligence lassosum.MultiPRS LDpred2.MultiPRS 0.102 0.103 0.000 7.65e-01 0.097 0.094 0.003 2.60e-01
Intelligence PRScs.10FCVal LDpred2.MultiPRS 0.099 0.103 -0.003 6.67e-01 0.089 0.094 -0.005 1.26e-01
Intelligence PRScs.MultiPRS LDpred2.MultiPRS 0.100 0.103 -0.002 6.99e-02 0.093 0.094 -0.001 6.47e-01
Intelligence lassosum.PseudoVal LDpred2.MultiPRS 0.064 0.103 -0.039 4.56e-08 0.059 0.094 -0.036 2.02e-05
Intelligence LDpred2.PseudoVal LDpred2.MultiPRS 0.100 0.103 -0.002 7.61e-01 0.093 0.094 -0.002 5.30e-01
Intelligence LDpred1.MultiPRS LDpred2.MultiPRS 0.101 0.103 -0.001 8.60e-01 0.093 0.094 -0.001 6.99e-01
Intelligence LDpred2.MultiPRS LDpred2.MultiPRS 0.103 0.103 0.000 1.00e+00 0.094 0.094 0.000 1.00e+00
Intelligence LDpred1.Inf LDpred2.10FCVal 0.100 0.103 -0.003 3.29e-02 0.092 0.093 -0.002 5.88e-01
Intelligence PRScs.MultiPRS LDpred2.10FCVal 0.100 0.103 -0.003 7.13e-01 0.093 0.093 0.000 9.78e-01
Intelligence LDpred2.MultiPRS LDpred2.10FCVal 0.103 0.103 0.000 9.52e-01 0.094 0.093 0.001 4.31e-01
Intelligence PRScs.PseudoVal LDpred2.10FCVal 0.099 0.103 -0.004 1.94e-03 0.092 0.093 -0.001 8.02e-01
Intelligence LDpred2.10FCVal LDpred2.10FCVal 0.103 0.103 0.000 1.00e+00 0.093 0.093 0.000 1.00e+00
Intelligence lassosum.MultiPRS LDpred2.10FCVal 0.102 0.103 -0.001 9.09e-01 0.097 0.093 0.004 1.08e-01
Intelligence LDpred1.10FCVal LDpred2.10FCVal 0.102 0.103 -0.001 3.13e-01 0.092 0.093 -0.001 6.60e-01
Intelligence All.MultiPRS LDpred2.10FCVal 0.102 0.103 0.000 9.44e-01 0.097 0.093 0.004 6.03e-02
Intelligence SBayesR.PseudoVal LDpred2.10FCVal 0.072 0.103 -0.030 2.33e-14 0.065 0.093 -0.028 4.22e-04
Intelligence DBSLMM.PseudoVal LDpred2.10FCVal 0.089 0.103 -0.014 4.46e-10 0.079 0.093 -0.014 3.02e-03
Intelligence pT+clump.MultiPRS LDpred2.10FCVal 0.086 0.103 -0.016 1.91e-02 0.080 0.093 -0.013 2.37e-02
Intelligence lassosum.PseudoVal LDpred2.10FCVal 0.064 0.103 -0.039 5.06e-21 0.059 0.093 -0.034 2.88e-05
Intelligence PRScs.10FCVal LDpred2.10FCVal 0.099 0.103 -0.003 1.54e-02 0.089 0.093 -0.004 2.02e-01
Intelligence lassosum.10FCVal LDpred2.10FCVal 0.099 0.103 -0.004 1.72e-02 0.093 0.093 0.000 9.64e-01
Intelligence SBLUP.Inf LDpred2.10FCVal 0.100 0.103 -0.003 3.38e-02 0.092 0.093 -0.001 7.92e-01
Intelligence LDpred2.PseudoVal LDpred2.10FCVal 0.100 0.103 -0.003 1.99e-02 0.093 0.093 -0.001 8.20e-01
Intelligence pT+clump.10FCVal LDpred2.10FCVal 0.084 0.103 -0.019 1.51e-08 0.074 0.093 -0.019 3.90e-03
Intelligence LDpred2.Inf LDpred2.10FCVal 0.101 0.103 -0.002 3.96e-02 0.093 0.093 0.000 9.22e-01
Intelligence LDpred1.MultiPRS LDpred2.10FCVal 0.101 0.103 -0.002 8.13e-01 0.093 0.093 0.000 9.88e-01
Intelligence lassosum.10FCVal LDpred2.PseudoVal 0.099 0.100 -0.001 4.70e-01 0.093 0.093 0.001 8.65e-01
Intelligence SBLUP.Inf LDpred2.PseudoVal 0.100 0.100 0.000 9.74e-01 0.092 0.093 0.000 8.88e-01
Intelligence SBayesR.PseudoVal LDpred2.PseudoVal 0.072 0.100 -0.028 3.97e-11 0.065 0.093 -0.028 1.01e-03
Intelligence All.MultiPRS LDpred2.PseudoVal 0.102 0.100 0.002 7.68e-01 0.097 0.093 0.005 1.16e-01
Intelligence PRScs.PseudoVal LDpred2.PseudoVal 0.099 0.100 -0.002 2.87e-01 0.092 0.093 0.000 9.51e-01
Intelligence lassosum.MultiPRS LDpred2.PseudoVal 0.102 0.100 0.002 8.02e-01 0.097 0.093 0.004 1.72e-01
Intelligence PRScs.MultiPRS LDpred2.PseudoVal 0.100 0.100 0.000 9.98e-01 0.093 0.093 0.000 8.84e-01
Intelligence LDpred2.MultiPRS LDpred2.PseudoVal 0.103 0.100 0.002 7.61e-01 0.094 0.093 0.002 5.30e-01
Intelligence PRScs.10FCVal LDpred2.PseudoVal 0.099 0.100 -0.001 6.14e-01 0.089 0.093 -0.003 3.70e-01
Intelligence LDpred2.PseudoVal LDpred2.PseudoVal 0.100 0.100 0.000 1.00e+00 0.093 0.093 0.000 1.00e+00
Intelligence pT+clump.MultiPRS LDpred2.PseudoVal 0.086 0.100 -0.014 4.82e-02 0.080 0.093 -0.013 4.22e-02
Intelligence pT+clump.10FCVal LDpred2.PseudoVal 0.084 0.100 -0.017 4.12e-07 0.074 0.093 -0.019 3.63e-03
Intelligence lassosum.PseudoVal LDpred2.PseudoVal 0.064 0.100 -0.037 7.66e-14 0.059 0.093 -0.034 4.57e-04
Intelligence LDpred1.Inf LDpred2.PseudoVal 0.100 0.100 -0.001 5.80e-01 0.092 0.093 -0.001 5.73e-01
Intelligence LDpred1.MultiPRS LDpred2.PseudoVal 0.101 0.100 0.001 8.97e-01 0.093 0.093 0.001 8.30e-01
Intelligence LDpred1.10FCVal LDpred2.PseudoVal 0.102 0.100 0.002 2.60e-01 0.092 0.093 0.000 8.74e-01
Intelligence LDpred2.Inf LDpred2.PseudoVal 0.101 0.100 0.000 5.75e-01 0.093 0.093 0.000 7.00e-01
Intelligence LDpred2.10FCVal LDpred2.PseudoVal 0.103 0.100 0.003 1.99e-02 0.093 0.093 0.001 8.20e-01
Intelligence DBSLMM.PseudoVal LDpred2.PseudoVal 0.089 0.100 -0.012 2.25e-06 0.079 0.093 -0.013 7.90e-03
Intelligence pT+clump.MultiPRS LDpred2.Inf 0.086 0.101 -0.014 4.49e-02 0.080 0.093 -0.013 3.31e-02
Intelligence lassosum.MultiPRS LDpred2.Inf 0.102 0.101 0.002 8.25e-01 0.097 0.093 0.004 2.08e-01
Intelligence SBayesR.PseudoVal LDpred2.Inf 0.072 0.101 -0.028 2.65e-11 0.065 0.093 -0.028 8.83e-04
Intelligence All.MultiPRS LDpred2.Inf 0.102 0.101 0.002 7.90e-01 0.097 0.093 0.005 1.38e-01
Intelligence SBLUP.Inf LDpred2.Inf 0.100 0.101 0.000 6.15e-01 0.092 0.093 0.000 5.80e-01
Intelligence LDpred2.PseudoVal LDpred2.Inf 0.100 0.101 0.000 5.75e-01 0.093 0.093 0.000 7.00e-01
Intelligence PRScs.MultiPRS LDpred2.Inf 0.100 0.101 0.000 9.75e-01 0.093 0.093 0.000 9.56e-01
Intelligence LDpred2.MultiPRS LDpred2.Inf 0.103 0.101 0.002 7.83e-01 0.094 0.093 0.001 6.09e-01
Intelligence PRScs.10FCVal LDpred2.Inf 0.099 0.101 -0.001 5.31e-01 0.089 0.093 -0.003 3.27e-01
Intelligence LDpred1.Inf LDpred2.Inf 0.100 0.101 -0.001 4.16e-01 0.092 0.093 -0.001 4.56e-01
Intelligence LDpred1.MultiPRS LDpred2.Inf 0.101 0.101 0.001 9.20e-01 0.093 0.093 0.000 9.15e-01
Intelligence pT+clump.10FCVal LDpred2.Inf 0.084 0.101 -0.017 1.09e-07 0.074 0.093 -0.019 2.20e-03
Intelligence lassosum.PseudoVal LDpred2.Inf 0.064 0.101 -0.037 8.04e-14 0.059 0.093 -0.034 4.46e-04
Intelligence PRScs.PseudoVal LDpred2.Inf 0.099 0.101 -0.002 2.33e-01 0.092 0.093 0.000 8.87e-01
Intelligence DBSLMM.PseudoVal LDpred2.Inf 0.089 0.101 -0.012 1.80e-06 0.079 0.093 -0.013 7.09e-03
Intelligence LDpred1.10FCVal LDpred2.Inf 0.102 0.101 0.001 3.17e-01 0.092 0.093 -0.001 7.87e-01
Intelligence LDpred2.Inf LDpred2.Inf 0.101 0.101 0.000 1.00e+00 0.093 0.093 0.000 1.00e+00
Intelligence lassosum.10FCVal LDpred2.Inf 0.099 0.101 -0.002 3.76e-01 0.093 0.093 0.000 9.17e-01
Intelligence LDpred2.10FCVal LDpred2.Inf 0.103 0.101 0.002 3.96e-02 0.093 0.093 0.000 9.22e-01
Intelligence PRScs.10FCVal PRScs.MultiPRS 0.099 0.100 -0.001 9.02e-01 0.089 0.093 -0.004 3.44e-02
Intelligence LDpred1.10FCVal PRScs.MultiPRS 0.102 0.100 0.002 8.29e-01 0.092 0.093 -0.001 7.35e-01
Intelligence lassosum.MultiPRS PRScs.MultiPRS 0.102 0.100 0.002 2.11e-01 0.097 0.093 0.004 1.71e-01
Intelligence LDpred2.MultiPRS PRScs.MultiPRS 0.103 0.100 0.002 6.99e-02 0.094 0.093 0.001 6.47e-01
Intelligence All.MultiPRS PRScs.MultiPRS 0.102 0.100 0.002 1.57e-01 0.097 0.093 0.004 1.30e-01
Intelligence PRScs.PseudoVal PRScs.MultiPRS 0.099 0.100 -0.002 7.95e-01 0.092 0.093 -0.001 7.53e-01
Intelligence LDpred1.MultiPRS PRScs.MultiPRS 0.101 0.100 0.001 8.94e-01 0.093 0.093 0.000 9.73e-01
Intelligence pT+clump.MultiPRS PRScs.MultiPRS 0.086 0.100 -0.014 4.82e-02 0.080 0.093 -0.013 1.80e-02
Intelligence lassosum.PseudoVal PRScs.MultiPRS 0.064 0.100 -0.037 2.41e-07 0.059 0.093 -0.034 2.23e-05
Intelligence SBayesR.PseudoVal PRScs.MultiPRS 0.072 0.100 -0.028 7.59e-05 0.065 0.093 -0.028 4.86e-04
Intelligence DBSLMM.PseudoVal PRScs.MultiPRS 0.089 0.100 -0.012 9.48e-02 0.079 0.093 -0.014 4.48e-03
Intelligence SBLUP.Inf PRScs.MultiPRS 0.100 0.100 0.000 9.96e-01 0.092 0.093 -0.001 8.46e-01
Intelligence LDpred2.Inf PRScs.MultiPRS 0.101 0.100 0.000 9.75e-01 0.093 0.093 0.000 9.56e-01
Intelligence pT+clump.10FCVal PRScs.MultiPRS 0.084 0.100 -0.016 1.94e-02 0.074 0.093 -0.019 2.92e-03
Intelligence LDpred2.10FCVal PRScs.MultiPRS 0.103 0.100 0.003 7.13e-01 0.093 0.093 0.000 9.78e-01
Intelligence lassosum.10FCVal PRScs.MultiPRS 0.099 0.100 -0.001 8.43e-01 0.093 0.093 0.000 9.49e-01
Intelligence LDpred2.PseudoVal PRScs.MultiPRS 0.100 0.100 0.000 9.98e-01 0.093 0.093 0.000 8.84e-01
Intelligence LDpred1.Inf PRScs.MultiPRS 0.100 0.100 -0.001 9.41e-01 0.092 0.093 -0.001 6.49e-01
Intelligence PRScs.MultiPRS PRScs.MultiPRS 0.100 0.100 0.000 1.00e+00 0.093 0.093 0.000 1.00e+00
Intelligence LDpred2.PseudoVal PRScs.10FCVal 0.100 0.099 0.001 6.14e-01 0.093 0.089 0.003 3.70e-01
Intelligence PRScs.10FCVal PRScs.10FCVal 0.099 0.099 0.000 1.00e+00 0.089 0.089 0.000 1.00e+00
Intelligence LDpred2.MultiPRS PRScs.10FCVal 0.103 0.099 0.003 6.67e-01 0.094 0.089 0.005 1.26e-01
Intelligence pT+clump.MultiPRS PRScs.10FCVal 0.086 0.099 -0.013 6.41e-02 0.080 0.089 -0.010 1.03e-01
Intelligence LDpred1.Inf PRScs.10FCVal 0.100 0.099 0.000 8.53e-01 0.092 0.089 0.002 5.80e-01
Intelligence LDpred1.MultiPRS PRScs.10FCVal 0.101 0.099 0.002 7.98e-01 0.093 0.089 0.004 2.64e-01
Intelligence pT+clump.10FCVal PRScs.10FCVal 0.084 0.099 -0.016 3.75e-06 0.074 0.089 -0.016 1.93e-02
Intelligence lassosum.PseudoVal PRScs.10FCVal 0.064 0.099 -0.036 3.55e-17 0.059 0.089 -0.031 2.19e-04
Intelligence PRScs.PseudoVal PRScs.10FCVal 0.099 0.099 -0.001 5.81e-01 0.092 0.089 0.003 4.06e-01
Intelligence DBSLMM.PseudoVal PRScs.10FCVal 0.089 0.099 -0.011 3.01e-05 0.079 0.089 -0.010 5.47e-02
Intelligence SBLUP.Inf PRScs.10FCVal 0.100 0.099 0.001 6.00e-01 0.092 0.089 0.003 3.81e-01
Intelligence LDpred2.Inf PRScs.10FCVal 0.101 0.099 0.001 5.31e-01 0.093 0.089 0.003 3.27e-01
Intelligence lassosum.10FCVal PRScs.10FCVal 0.099 0.099 -0.001 7.79e-01 0.093 0.089 0.004 3.10e-01
Intelligence LDpred2.10FCVal PRScs.10FCVal 0.103 0.099 0.003 1.54e-02 0.093 0.089 0.004 2.02e-01
Intelligence lassosum.MultiPRS PRScs.10FCVal 0.102 0.099 0.003 7.07e-01 0.097 0.089 0.007 3.31e-02
Intelligence LDpred1.10FCVal PRScs.10FCVal 0.102 0.099 0.002 1.28e-01 0.092 0.089 0.003 3.87e-01
Intelligence All.MultiPRS PRScs.10FCVal 0.102 0.099 0.003 6.74e-01 0.097 0.089 0.008 2.28e-02
Intelligence SBayesR.PseudoVal PRScs.10FCVal 0.072 0.099 -0.027 5.13e-11 0.065 0.089 -0.025 2.80e-03
Intelligence PRScs.MultiPRS PRScs.10FCVal 0.100 0.099 0.001 9.02e-01 0.093 0.089 0.004 3.44e-02
Intelligence All.MultiPRS PRScs.PseudoVal 0.102 0.099 0.004 5.78e-01 0.097 0.092 0.005 1.50e-01
Intelligence pT+clump.MultiPRS PRScs.PseudoVal 0.086 0.099 -0.012 8.64e-02 0.080 0.092 -0.012 3.40e-02
Intelligence LDpred2.PseudoVal PRScs.PseudoVal 0.100 0.099 0.002 2.87e-01 0.093 0.092 0.000 9.51e-01
Intelligence SBayesR.PseudoVal PRScs.PseudoVal 0.072 0.099 -0.026 2.18e-10 0.065 0.092 -0.028 8.15e-04
Intelligence LDpred2.MultiPRS PRScs.PseudoVal 0.103 0.099 0.004 5.71e-01 0.094 0.092 0.002 5.69e-01
Intelligence SBLUP.Inf PRScs.PseudoVal 0.100 0.099 0.002 2.73e-01 0.092 0.092 0.000 9.81e-01
Intelligence LDpred1.Inf PRScs.PseudoVal 0.100 0.099 0.001 4.73e-01 0.092 0.092 -0.001 8.18e-01
Intelligence PRScs.10FCVal PRScs.PseudoVal 0.099 0.099 0.001 5.81e-01 0.089 0.092 -0.003 4.06e-01
Intelligence LDpred2.Inf PRScs.PseudoVal 0.101 0.099 0.002 2.33e-01 0.093 0.092 0.000 8.87e-01
Intelligence PRScs.PseudoVal PRScs.PseudoVal 0.099 0.099 0.000 1.00e+00 0.092 0.092 0.000 1.00e+00
Intelligence LDpred2.10FCVal PRScs.PseudoVal 0.103 0.099 0.004 1.94e-03 0.093 0.092 0.001 8.02e-01
Intelligence pT+clump.10FCVal PRScs.PseudoVal 0.084 0.099 -0.015 1.37e-05 0.074 0.092 -0.018 5.46e-03
Intelligence PRScs.MultiPRS PRScs.PseudoVal 0.100 0.099 0.002 7.95e-01 0.093 0.092 0.001 7.53e-01
Intelligence lassosum.PseudoVal PRScs.PseudoVal 0.064 0.099 -0.035 2.40e-16 0.059 0.092 -0.034 5.12e-05
Intelligence lassosum.10FCVal PRScs.PseudoVal 0.099 0.099 0.000 8.12e-01 0.093 0.092 0.001 8.14e-01
Intelligence LDpred1.MultiPRS PRScs.PseudoVal 0.101 0.099 0.003 6.95e-01 0.093 0.092 0.001 8.15e-01
Intelligence lassosum.MultiPRS PRScs.PseudoVal 0.102 0.099 0.004 6.08e-01 0.097 0.092 0.004 1.92e-01
Intelligence LDpred1.10FCVal PRScs.PseudoVal 0.102 0.099 0.003 2.86e-02 0.092 0.092 0.000 9.47e-01
Intelligence DBSLMM.PseudoVal PRScs.PseudoVal 0.089 0.099 -0.010 1.36e-04 0.079 0.092 -0.013 1.24e-02
Intelligence All.MultiPRS pT+clump.MultiPRS 0.102 0.086 0.016 2.29e-02 0.097 0.080 0.017 2.02e-03
Intelligence SBayesR.PseudoVal pT+clump.MultiPRS 0.072 0.086 -0.014 4.71e-02 0.065 0.080 -0.015 9.33e-02
Intelligence LDpred1.MultiPRS pT+clump.MultiPRS 0.101 0.086 0.015 3.55e-02 0.093 0.080 0.013 2.26e-02
Intelligence pT+clump.MultiPRS pT+clump.MultiPRS 0.086 0.086 0.000 1.00e+00 0.080 0.080 0.000 1.00e+00
Intelligence lassosum.PseudoVal pT+clump.MultiPRS 0.064 0.086 -0.023 1.32e-03 0.059 0.080 -0.021 1.36e-02
Intelligence PRScs.10FCVal pT+clump.MultiPRS 0.099 0.086 0.013 6.41e-02 0.089 0.080 0.010 1.03e-01
Intelligence DBSLMM.PseudoVal pT+clump.MultiPRS 0.089 0.086 0.002 7.63e-01 0.079 0.080 0.000 9.54e-01
Intelligence SBLUP.Inf pT+clump.MultiPRS 0.100 0.086 0.014 4.79e-02 0.092 0.080 0.013 3.51e-02
Intelligence LDpred2.Inf pT+clump.MultiPRS 0.101 0.086 0.014 4.49e-02 0.093 0.080 0.013 3.31e-02
Intelligence pT+clump.10FCVal pT+clump.MultiPRS 0.084 0.086 -0.003 7.09e-01 0.074 0.080 -0.006 3.41e-02
Intelligence LDpred2.10FCVal pT+clump.MultiPRS 0.103 0.086 0.016 1.91e-02 0.093 0.080 0.013 2.37e-02
Intelligence PRScs.PseudoVal pT+clump.MultiPRS 0.099 0.086 0.012 8.64e-02 0.092 0.080 0.012 3.40e-02
Intelligence LDpred1.10FCVal pT+clump.MultiPRS 0.102 0.086 0.015 2.86e-02 0.092 0.080 0.012 3.14e-02
Intelligence LDpred1.Inf pT+clump.MultiPRS 0.100 0.086 0.013 5.75e-02 0.092 0.080 0.012 5.65e-02
Intelligence PRScs.MultiPRS pT+clump.MultiPRS 0.100 0.086 0.014 4.82e-02 0.093 0.080 0.013 1.80e-02
Intelligence lassosum.10FCVal pT+clump.MultiPRS 0.099 0.086 0.012 7.55e-02 0.093 0.080 0.013 1.31e-02
Intelligence LDpred2.PseudoVal pT+clump.MultiPRS 0.100 0.086 0.014 4.82e-02 0.093 0.080 0.013 4.22e-02
Intelligence lassosum.MultiPRS pT+clump.MultiPRS 0.102 0.086 0.016 2.57e-02 0.097 0.080 0.017 4.08e-03
Intelligence LDpred2.MultiPRS pT+clump.MultiPRS 0.103 0.086 0.016 2.23e-02 0.094 0.080 0.014 1.34e-02
Intelligence LDpred2.10FCVal pT+clump.10FCVal 0.103 0.084 0.019 1.51e-08 0.093 0.074 0.019 3.90e-03
Intelligence pT+clump.MultiPRS pT+clump.10FCVal 0.086 0.084 0.003 7.09e-01 0.080 0.074 0.006 3.41e-02
Intelligence LDpred2.Inf pT+clump.10FCVal 0.101 0.084 0.017 1.09e-07 0.093 0.074 0.019 2.20e-03
Intelligence SBayesR.PseudoVal pT+clump.10FCVal 0.072 0.084 -0.011 1.92e-02 0.065 0.074 -0.009 3.36e-01
Intelligence PRScs.MultiPRS pT+clump.10FCVal 0.100 0.084 0.016 1.94e-02 0.093 0.074 0.019 2.92e-03
Intelligence SBLUP.Inf pT+clump.10FCVal 0.100 0.084 0.017 7.89e-08 0.092 0.074 0.018 2.16e-03
Intelligence lassosum.MultiPRS pT+clump.10FCVal 0.102 0.084 0.018 9.58e-03 0.097 0.074 0.023 5.90e-04
Intelligence PRScs.10FCVal pT+clump.10FCVal 0.099 0.084 0.016 3.75e-06 0.089 0.074 0.016 1.93e-02
Intelligence LDpred2.MultiPRS pT+clump.10FCVal 0.103 0.084 0.019 8.16e-03 0.094 0.074 0.020 2.14e-03
Intelligence lassosum.10FCVal pT+clump.10FCVal 0.099 0.084 0.015 3.72e-07 0.093 0.074 0.019 9.65e-04
Intelligence LDpred2.PseudoVal pT+clump.10FCVal 0.100 0.084 0.017 4.12e-07 0.093 0.074 0.019 3.63e-03
Intelligence LDpred1.MultiPRS pT+clump.10FCVal 0.101 0.084 0.017 1.33e-02 0.093 0.074 0.019 2.30e-03
Intelligence pT+clump.10FCVal pT+clump.10FCVal 0.084 0.084 0.000 1.00e+00 0.074 0.074 0.000 1.00e+00
Intelligence All.MultiPRS pT+clump.10FCVal 0.102 0.084 0.019 8.46e-03 0.097 0.074 0.023 2.37e-04
Intelligence LDpred1.Inf pT+clump.10FCVal 0.100 0.084 0.016 4.03e-07 0.092 0.074 0.018 4.50e-03
Intelligence DBSLMM.PseudoVal pT+clump.10FCVal 0.089 0.084 0.005 2.18e-01 0.079 0.074 0.006 4.62e-01
Intelligence LDpred1.10FCVal pT+clump.10FCVal 0.102 0.084 0.018 2.02e-08 0.092 0.074 0.018 3.88e-03
Intelligence lassosum.PseudoVal pT+clump.10FCVal 0.064 0.084 -0.020 1.39e-04 0.059 0.074 -0.015 1.38e-01
Intelligence PRScs.PseudoVal pT+clump.10FCVal 0.099 0.084 0.015 1.37e-05 0.092 0.074 0.018 5.46e-03
Intelligence pT+clump.MultiPRS SBayesR.PseudoVal 0.086 0.072 0.014 4.71e-02 0.080 0.065 0.015 9.33e-02
Intelligence LDpred1.10FCVal SBayesR.PseudoVal 0.102 0.072 0.029 6.95e-13 0.092 0.065 0.028 8.80e-04
Intelligence PRScs.10FCVal SBayesR.PseudoVal 0.099 0.072 0.027 5.13e-11 0.089 0.065 0.025 2.80e-03
Intelligence LDpred2.10FCVal SBayesR.PseudoVal 0.103 0.072 0.030 2.33e-14 0.093 0.065 0.028 4.22e-04
Intelligence lassosum.10FCVal SBayesR.PseudoVal 0.099 0.072 0.026 1.78e-10 0.093 0.065 0.029 6.09e-04
Intelligence LDpred2.PseudoVal SBayesR.PseudoVal 0.100 0.072 0.028 3.97e-11 0.093 0.065 0.028 1.01e-03
Intelligence lassosum.MultiPRS SBayesR.PseudoVal 0.102 0.072 0.030 2.60e-05 0.097 0.065 0.032 1.03e-04
Intelligence LDpred2.MultiPRS SBayesR.PseudoVal 0.103 0.072 0.030 2.02e-05 0.094 0.065 0.029 2.94e-04
Intelligence All.MultiPRS SBayesR.PseudoVal 0.102 0.072 0.030 2.15e-05 0.097 0.065 0.033 4.97e-05
Intelligence PRScs.PseudoVal SBayesR.PseudoVal 0.099 0.072 0.026 2.18e-10 0.092 0.065 0.028 8.15e-04
Intelligence LDpred1.MultiPRS SBayesR.PseudoVal 0.101 0.072 0.029 4.38e-05 0.093 0.065 0.028 6.61e-04
Intelligence pT+clump.10FCVal SBayesR.PseudoVal 0.084 0.072 0.011 1.92e-02 0.074 0.065 0.009 3.36e-01
Intelligence lassosum.PseudoVal SBayesR.PseudoVal 0.064 0.072 -0.009 7.99e-02 0.059 0.065 -0.006 5.42e-01
Intelligence SBayesR.PseudoVal SBayesR.PseudoVal 0.072 0.072 0.000 1.00e+00 0.065 0.065 0.000 1.00e+00
Intelligence DBSLMM.PseudoVal SBayesR.PseudoVal 0.089 0.072 0.016 2.04e-04 0.079 0.065 0.015 9.17e-02
Intelligence SBLUP.Inf SBayesR.PseudoVal 0.100 0.072 0.028 3.63e-11 0.092 0.065 0.028 1.05e-03
Intelligence LDpred2.Inf SBayesR.PseudoVal 0.101 0.072 0.028 2.65e-11 0.093 0.065 0.028 8.83e-04
Intelligence LDpred1.Inf SBayesR.PseudoVal 0.100 0.072 0.027 1.56e-10 0.092 0.065 0.027 1.78e-03
Intelligence PRScs.MultiPRS SBayesR.PseudoVal 0.100 0.072 0.028 7.59e-05 0.093 0.065 0.028 4.86e-04
Intelligence LDpred2.10FCVal SBLUP.Inf 0.103 0.100 0.003 3.38e-02 0.093 0.092 0.001 7.92e-01
Intelligence PRScs.PseudoVal SBLUP.Inf 0.099 0.100 -0.002 2.73e-01 0.092 0.092 0.000 9.81e-01
Intelligence LDpred1.10FCVal SBLUP.Inf 0.102 0.100 0.001 2.40e-01 0.092 0.092 0.000 9.10e-01
Intelligence LDpred2.Inf SBLUP.Inf 0.101 0.100 0.000 6.15e-01 0.093 0.092 0.000 5.80e-01
Intelligence SBayesR.PseudoVal SBLUP.Inf 0.072 0.100 -0.028 3.63e-11 0.065 0.092 -0.028 1.05e-03
Intelligence lassosum.10FCVal SBLUP.Inf 0.099 0.100 -0.001 4.26e-01 0.093 0.092 0.001 8.23e-01
Intelligence pT+clump.MultiPRS SBLUP.Inf 0.086 0.100 -0.014 4.79e-02 0.080 0.092 -0.013 3.51e-02
Intelligence lassosum.MultiPRS SBLUP.Inf 0.102 0.100 0.002 8.04e-01 0.097 0.092 0.004 1.66e-01
Intelligence PRScs.10FCVal SBLUP.Inf 0.099 0.100 -0.001 6.00e-01 0.089 0.092 -0.003 3.81e-01
Intelligence PRScs.MultiPRS SBLUP.Inf 0.100 0.100 0.000 9.96e-01 0.093 0.092 0.001 8.46e-01
Intelligence LDpred1.MultiPRS SBLUP.Inf 0.101 0.100 0.001 8.99e-01 0.093 0.092 0.001 7.78e-01
Intelligence LDpred2.PseudoVal SBLUP.Inf 0.100 0.100 0.000 9.74e-01 0.093 0.092 0.000 8.88e-01
Intelligence LDpred1.Inf SBLUP.Inf 0.100 0.100 -0.001 5.31e-01 0.092 0.092 -0.001 5.93e-01
Intelligence LDpred2.MultiPRS SBLUP.Inf 0.103 0.100 0.002 7.62e-01 0.094 0.092 0.002 5.15e-01
Intelligence All.MultiPRS SBLUP.Inf 0.102 0.100 0.002 7.70e-01 0.097 0.092 0.005 1.09e-01
Intelligence SBLUP.Inf SBLUP.Inf 0.100 0.100 0.000 1.00e+00 0.092 0.092 0.000 1.00e+00
Intelligence DBSLMM.PseudoVal SBLUP.Inf 0.089 0.100 -0.012 2.24e-06 0.079 0.092 -0.013 8.58e-03
Intelligence pT+clump.10FCVal SBLUP.Inf 0.084 0.100 -0.017 7.89e-08 0.074 0.092 -0.018 2.16e-03
Intelligence lassosum.PseudoVal SBLUP.Inf 0.064 0.100 -0.037 1.05e-13 0.059 0.092 -0.034 5.20e-04
Height LDpred2.PseudoVal All.MultiPRS 0.304 0.358 -0.054 3.80e-18 0.304 0.361 -0.057 2.45e-27
Height pT+clump.10FCVal All.MultiPRS 0.304 0.358 -0.054 5.46e-18 0.299 0.361 -0.062 2.85e-32
Height LDpred2.MultiPRS All.MultiPRS 0.350 0.358 -0.008 1.85e-01 0.354 0.361 -0.007 1.45e-03
Height PRScs.PseudoVal All.MultiPRS 0.346 0.358 -0.012 5.07e-02 0.344 0.361 -0.017 3.90e-11
Height LDpred1.Inf All.MultiPRS 0.299 0.358 -0.059 1.50e-21 0.303 0.361 -0.057 9.27e-26
Height PRScs.MultiPRS All.MultiPRS 0.347 0.358 -0.011 1.64e-19 0.345 0.361 -0.015 1.33e-10
Height LDpred2.Inf All.MultiPRS 0.305 0.358 -0.053 1.00e-17 0.305 0.361 -0.056 4.58e-27
Height lassosum.PseudoVal All.MultiPRS 0.285 0.358 -0.074 1.21e-31 0.281 0.361 -0.080 7.75e-40
Height LDpred2.10FCVal All.MultiPRS 0.343 0.358 -0.015 1.15e-02 0.346 0.361 -0.015 2.57e-07
Height lassosum.MultiPRS All.MultiPRS 0.350 0.358 -0.008 2.22e-01 0.348 0.361 -0.012 2.46e-09
Height LDpred1.10FCVal All.MultiPRS 0.300 0.358 -0.058 8.28e-21 0.301 0.361 -0.060 5.55e-28
Height All.MultiPRS All.MultiPRS 0.358 0.358 0.000 1.00e+00 0.361 0.361 0.000 1.00e+00
Height SBayesR.PseudoVal All.MultiPRS 0.344 0.358 -0.014 2.11e-02 0.343 0.361 -0.017 2.98e-10
Height LDpred1.MultiPRS All.MultiPRS 0.303 0.358 -0.055 1.04e-17 0.307 0.361 -0.054 9.75e-25
Height pT+clump.MultiPRS All.MultiPRS 0.320 0.358 -0.038 2.44e-09 0.313 0.361 -0.048 2.13e-27
Height lassosum.10FCVal All.MultiPRS 0.347 0.358 -0.011 7.97e-02 0.346 0.361 -0.015 3.22e-10
Height PRScs.10FCVal All.MultiPRS 0.345 0.358 -0.013 3.43e-02 0.344 0.361 -0.017 4.24e-11
Height DBSLMM.PseudoVal All.MultiPRS 0.332 0.358 -0.026 3.00e-05 0.327 0.361 -0.033 5.35e-20
Height SBLUP.Inf All.MultiPRS 0.293 0.358 -0.065 4.37e-25 0.294 0.361 -0.067 1.41e-32
Height SBayesR.PseudoVal DBSLMM.PseudoVal 0.344 0.332 0.012 2.45e-06 0.343 0.327 0.016 1.18e-03
Height LDpred2.Inf DBSLMM.PseudoVal 0.305 0.332 -0.028 9.47e-46 0.305 0.327 -0.023 5.07e-09
Height pT+clump.10FCVal DBSLMM.PseudoVal 0.304 0.332 -0.028 2.05e-18 0.299 0.327 -0.029 9.51e-06
Height PRScs.10FCVal DBSLMM.PseudoVal 0.345 0.332 0.013 3.97e-13 0.344 0.327 0.016 2.79e-06
Height PRScs.PseudoVal DBSLMM.PseudoVal 0.346 0.332 0.014 1.74e-20 0.344 0.327 0.016 3.34e-08
Height pT+clump.MultiPRS DBSLMM.PseudoVal 0.320 0.332 -0.013 4.90e-02 0.313 0.327 -0.015 2.75e-03
Height LDpred1.Inf DBSLMM.PseudoVal 0.299 0.332 -0.034 3.49e-70 0.303 0.327 -0.024 4.78e-10
Height lassosum.MultiPRS DBSLMM.PseudoVal 0.350 0.332 0.018 5.18e-03 0.348 0.327 0.021 4.97e-09
Height LDpred2.10FCVal DBSLMM.PseudoVal 0.343 0.332 0.010 8.04e-10 0.346 0.327 0.019 2.03e-08
Height lassosum.PseudoVal DBSLMM.PseudoVal 0.285 0.332 -0.048 1.40e-36 0.281 0.327 -0.046 1.21e-09
Height LDpred1.10FCVal DBSLMM.PseudoVal 0.300 0.332 -0.033 8.02e-57 0.301 0.327 -0.026 1.81e-10
Height LDpred1.MultiPRS DBSLMM.PseudoVal 0.303 0.332 -0.030 5.90e-06 0.307 0.327 -0.021 2.55e-08
Height PRScs.MultiPRS DBSLMM.PseudoVal 0.347 0.332 0.015 1.64e-02 0.345 0.327 0.018 1.40e-08
Height All.MultiPRS DBSLMM.PseudoVal 0.358 0.332 0.026 3.00e-05 0.361 0.327 0.033 5.35e-20
Height LDpred2.PseudoVal DBSLMM.PseudoVal 0.304 0.332 -0.028 2.85e-47 0.304 0.327 -0.024 2.29e-09
Height DBSLMM.PseudoVal DBSLMM.PseudoVal 0.332 0.332 0.000 1.00e+00 0.327 0.327 0.000 1.00e+00
Height LDpred2.MultiPRS DBSLMM.PseudoVal 0.350 0.332 0.017 7.34e-03 0.354 0.327 0.026 2.99e-12
Height lassosum.10FCVal DBSLMM.PseudoVal 0.347 0.332 0.015 4.76e-14 0.346 0.327 0.018 4.86e-06
Height SBLUP.Inf DBSLMM.PseudoVal 0.293 0.332 -0.039 9.41e-91 0.294 0.327 -0.034 1.65e-18
Height SBayesR.PseudoVal lassosum.MultiPRS 0.344 0.350 -0.006 3.17e-01 0.343 0.348 -0.005 1.60e-01
Height LDpred2.10FCVal lassosum.MultiPRS 0.343 0.350 -0.008 2.27e-01 0.346 0.348 -0.002 4.76e-01
Height LDpred1.10FCVal lassosum.MultiPRS 0.300 0.350 -0.051 5.85e-15 0.301 0.348 -0.047 1.35e-18
Height LDpred2.Inf lassosum.MultiPRS 0.305 0.350 -0.046 2.00e-12 0.305 0.348 -0.044 2.03e-16
Height PRScs.10FCVal lassosum.MultiPRS 0.345 0.350 -0.005 4.13e-01 0.344 0.348 -0.005 5.36e-02
Height PRScs.MultiPRS lassosum.MultiPRS 0.347 0.350 -0.003 6.20e-01 0.345 0.348 -0.003 1.57e-01
Height pT+clump.MultiPRS lassosum.MultiPRS 0.320 0.350 -0.031 1.90e-06 0.313 0.348 -0.036 6.06e-16
Height lassosum.MultiPRS lassosum.MultiPRS 0.350 0.350 0.000 1.00e+00 0.348 0.348 0.000 1.00e+00
Height lassosum.10FCVal lassosum.MultiPRS 0.347 0.350 -0.003 6.40e-01 0.346 0.348 -0.003 5.59e-02
Height LDpred2.MultiPRS lassosum.MultiPRS 0.350 0.350 -0.001 9.09e-01 0.354 0.348 0.005 6.88e-02
Height LDpred1.MultiPRS lassosum.MultiPRS 0.303 0.350 -0.047 2.64e-13 0.307 0.348 -0.042 7.22e-16
Height LDpred2.PseudoVal lassosum.MultiPRS 0.304 0.350 -0.046 9.16e-13 0.304 0.348 -0.045 1.49e-16
Height LDpred1.Inf lassosum.MultiPRS 0.299 0.350 -0.052 1.69e-15 0.303 0.348 -0.045 5.14e-17
Height pT+clump.10FCVal lassosum.MultiPRS 0.304 0.350 -0.046 9.87e-13 0.299 0.348 -0.050 8.33e-20
Height lassosum.PseudoVal lassosum.MultiPRS 0.285 0.350 -0.066 2.70e-24 0.281 0.348 -0.067 4.70e-31
Height SBLUP.Inf lassosum.MultiPRS 0.293 0.350 -0.057 2.04e-18 0.294 0.348 -0.055 2.87e-23
Height DBSLMM.PseudoVal lassosum.MultiPRS 0.332 0.350 -0.018 5.18e-03 0.327 0.348 -0.021 4.97e-09
Height All.MultiPRS lassosum.MultiPRS 0.358 0.350 0.008 2.22e-01 0.361 0.348 0.012 2.46e-09
Height PRScs.PseudoVal lassosum.MultiPRS 0.346 0.350 -0.004 5.09e-01 0.344 0.348 -0.005 5.46e-02
Height LDpred1.Inf lassosum.10FCVal 0.299 0.347 -0.049 4.71e-70 0.303 0.346 -0.042 4.21e-14
Height PRScs.10FCVal lassosum.10FCVal 0.345 0.347 -0.002 1.04e-01 0.344 0.346 -0.002 5.20e-01
Height LDpred2.MultiPRS lassosum.10FCVal 0.350 0.347 0.002 7.25e-01 0.354 0.346 0.008 8.36e-03
Height lassosum.10FCVal lassosum.10FCVal 0.347 0.347 0.000 1.00e+00 0.346 0.346 0.000 1.00e+00
Height PRScs.PseudoVal lassosum.10FCVal 0.346 0.347 -0.001 3.69e-01 0.344 0.346 -0.002 5.02e-01
Height DBSLMM.PseudoVal lassosum.10FCVal 0.332 0.347 -0.015 4.76e-14 0.327 0.346 -0.018 4.86e-06
Height SBLUP.Inf lassosum.10FCVal 0.293 0.347 -0.054 1.09e-80 0.294 0.346 -0.052 1.12e-19
Height LDpred2.Inf lassosum.10FCVal 0.305 0.347 -0.043 3.03e-54 0.305 0.346 -0.041 1.71e-13
Height pT+clump.10FCVal lassosum.10FCVal 0.304 0.347 -0.043 7.92e-53 0.299 0.346 -0.047 1.39e-16
Height LDpred2.10FCVal lassosum.10FCVal 0.343 0.347 -0.005 6.91e-03 0.346 0.346 0.000 9.23e-01
Height lassosum.MultiPRS lassosum.10FCVal 0.350 0.347 0.003 6.40e-01 0.348 0.346 0.003 5.59e-02
Height LDpred1.10FCVal lassosum.10FCVal 0.300 0.347 -0.048 3.10e-67 0.301 0.346 -0.045 1.12e-15
Height All.MultiPRS lassosum.10FCVal 0.358 0.347 0.011 7.97e-02 0.361 0.346 0.015 3.22e-10
Height SBayesR.PseudoVal lassosum.10FCVal 0.344 0.347 -0.003 8.62e-02 0.343 0.346 -0.002 5.64e-01
Height lassosum.PseudoVal lassosum.10FCVal 0.285 0.347 -0.063 2.48e-99 0.281 0.346 -0.065 1.96e-27
Height pT+clump.MultiPRS lassosum.10FCVal 0.320 0.347 -0.028 1.79e-05 0.313 0.346 -0.033 2.93e-13
Height LDpred2.PseudoVal lassosum.10FCVal 0.304 0.347 -0.043 6.26e-55 0.304 0.346 -0.042 1.17e-13
Height LDpred1.MultiPRS lassosum.10FCVal 0.303 0.347 -0.044 7.58e-12 0.307 0.346 -0.039 4.45e-13
Height PRScs.MultiPRS lassosum.10FCVal 0.347 0.347 0.000 9.78e-01 0.345 0.346 0.000 8.93e-01
Height lassosum.PseudoVal lassosum.PseudoVal 0.285 0.285 0.000 1.00e+00 0.281 0.281 0.000 1.00e+00
Height pT+clump.MultiPRS lassosum.PseudoVal 0.320 0.285 0.035 8.62e-08 0.313 0.281 0.032 6.86e-06
Height LDpred2.Inf lassosum.PseudoVal 0.305 0.285 0.020 8.20e-06 0.305 0.281 0.023 1.02e-02
Height SBayesR.PseudoVal lassosum.PseudoVal 0.344 0.285 0.059 1.17e-107 0.343 0.281 0.062 7.00e-31
Height PRScs.MultiPRS lassosum.PseudoVal 0.347 0.285 0.063 2.38e-23 0.345 0.281 0.064 1.13e-28
Height SBLUP.Inf lassosum.PseudoVal 0.293 0.285 0.009 5.90e-02 0.294 0.281 0.013 1.85e-01
Height lassosum.MultiPRS lassosum.PseudoVal 0.350 0.285 0.066 2.70e-24 0.348 0.281 0.067 4.70e-31
Height PRScs.10FCVal lassosum.PseudoVal 0.345 0.285 0.061 1.45e-106 0.344 0.281 0.063 1.20e-29
Height LDpred2.MultiPRS lassosum.PseudoVal 0.350 0.285 0.065 2.11e-23 0.354 0.281 0.073 8.00e-31
Height PRScs.PseudoVal lassosum.PseudoVal 0.346 0.285 0.062 6.18e-88 0.344 0.281 0.063 6.85e-24
Height LDpred2.PseudoVal lassosum.PseudoVal 0.304 0.285 0.020 1.89e-05 0.304 0.281 0.023 1.32e-02
Height LDpred1.MultiPRS lassosum.PseudoVal 0.303 0.285 0.018 5.30e-03 0.307 0.281 0.026 4.43e-03
Height pT+clump.10FCVal lassosum.PseudoVal 0.304 0.285 0.020 1.89e-08 0.299 0.281 0.018 1.14e-02
Height All.MultiPRS lassosum.PseudoVal 0.358 0.285 0.074 1.21e-31 0.361 0.281 0.080 7.75e-40
Height LDpred1.Inf lassosum.PseudoVal 0.299 0.285 0.014 2.14e-03 0.303 0.281 0.022 1.49e-02
Height DBSLMM.PseudoVal lassosum.PseudoVal 0.332 0.285 0.048 1.40e-36 0.327 0.281 0.046 1.21e-09
Height LDpred1.10FCVal lassosum.PseudoVal 0.300 0.285 0.015 7.59e-04 0.301 0.281 0.020 2.68e-02
Height lassosum.10FCVal lassosum.PseudoVal 0.347 0.285 0.063 2.48e-99 0.346 0.281 0.065 1.96e-27
Height LDpred2.10FCVal lassosum.PseudoVal 0.343 0.285 0.058 1.10e-57 0.346 0.281 0.065 4.47e-19
Height LDpred2.10FCVal LDpred1.MultiPRS 0.343 0.303 0.040 9.80e-10 0.346 0.307 0.039 1.00e-25
Height PRScs.PseudoVal LDpred1.MultiPRS 0.346 0.303 0.043 2.77e-11 0.344 0.307 0.037 1.52e-17
Height LDpred2.Inf LDpred1.MultiPRS 0.305 0.303 0.002 7.79e-01 0.305 0.307 -0.002 3.84e-01
Height pT+clump.10FCVal LDpred1.MultiPRS 0.304 0.303 0.001 8.33e-01 0.299 0.307 -0.008 3.07e-01
Height SBayesR.PseudoVal LDpred1.MultiPRS 0.344 0.303 0.041 2.48e-10 0.343 0.307 0.037 3.49e-08
Height All.MultiPRS LDpred1.MultiPRS 0.358 0.303 0.055 1.04e-17 0.361 0.307 0.054 9.75e-25
Height LDpred1.10FCVal LDpred1.MultiPRS 0.300 0.303 -0.003 6.24e-01 0.301 0.307 -0.006 1.77e-04
Height LDpred1.MultiPRS LDpred1.MultiPRS 0.303 0.303 0.000 1.00e+00 0.307 0.307 0.000 1.00e+00
Height PRScs.10FCVal LDpred1.MultiPRS 0.345 0.303 0.042 7.93e-11 0.344 0.307 0.037 2.87e-13
Height lassosum.10FCVal LDpred1.MultiPRS 0.347 0.303 0.044 7.58e-12 0.346 0.307 0.039 4.45e-13
Height pT+clump.MultiPRS LDpred1.MultiPRS 0.320 0.303 0.017 1.05e-02 0.313 0.307 0.006 3.22e-01
Height LDpred1.Inf LDpred1.MultiPRS 0.299 0.303 -0.004 5.14e-01 0.303 0.307 -0.003 5.54e-02
Height lassosum.MultiPRS LDpred1.MultiPRS 0.350 0.303 0.047 2.64e-13 0.348 0.307 0.042 7.22e-16
Height PRScs.MultiPRS LDpred1.MultiPRS 0.347 0.303 0.044 7.02e-12 0.345 0.307 0.039 1.96e-16
Height lassosum.PseudoVal LDpred1.MultiPRS 0.285 0.303 -0.018 5.30e-03 0.281 0.307 -0.026 4.43e-03
Height LDpred2.PseudoVal LDpred1.MultiPRS 0.304 0.303 0.001 8.63e-01 0.304 0.307 -0.003 2.62e-01
Height DBSLMM.PseudoVal LDpred1.MultiPRS 0.332 0.303 0.030 5.90e-06 0.327 0.307 0.021 2.55e-08
Height LDpred2.MultiPRS LDpred1.MultiPRS 0.350 0.303 0.047 5.77e-13 0.354 0.307 0.047 3.26e-22
Height SBLUP.Inf LDpred1.MultiPRS 0.293 0.303 -0.009 1.49e-01 0.294 0.307 -0.013 1.97e-09
Height All.MultiPRS LDpred1.Inf 0.358 0.299 0.059 1.50e-21 0.361 0.303 0.057 9.27e-26
Height LDpred2.PseudoVal LDpred1.Inf 0.304 0.299 0.005 2.72e-06 0.304 0.303 0.000 8.80e-01
Height SBayesR.PseudoVal LDpred1.Inf 0.344 0.299 0.045 1.85e-40 0.343 0.303 0.040 5.63e-09
Height LDpred2.MultiPRS LDpred1.Inf 0.350 0.299 0.051 3.07e-15 0.354 0.303 0.050 2.82e-23
Height PRScs.PseudoVal LDpred1.Inf 0.346 0.299 0.048 1.85e-100 0.344 0.303 0.040 3.43e-19
Height LDpred1.Inf LDpred1.Inf 0.299 0.299 0.000 1.00e+00 0.303 0.303 0.000 1.00e+00
Height pT+clump.10FCVal LDpred1.Inf 0.304 0.299 0.006 1.48e-01 0.299 0.303 -0.005 5.56e-01
Height PRScs.MultiPRS LDpred1.Inf 0.347 0.299 0.049 7.23e-15 0.345 0.303 0.042 7.00e-18
Height lassosum.10FCVal LDpred1.Inf 0.347 0.299 0.049 4.71e-70 0.346 0.303 0.042 4.21e-14
Height pT+clump.MultiPRS LDpred1.Inf 0.320 0.299 0.021 1.30e-03 0.313 0.303 0.009 1.30e-01
Height LDpred1.MultiPRS LDpred1.Inf 0.303 0.299 0.004 5.14e-01 0.307 0.303 0.003 5.54e-02
Height PRScs.10FCVal LDpred1.Inf 0.345 0.299 0.047 6.23e-71 0.344 0.303 0.040 1.44e-14
Height LDpred2.Inf LDpred1.Inf 0.305 0.299 0.006 6.28e-08 0.305 0.303 0.001 6.51e-01
Height SBLUP.Inf LDpred1.Inf 0.293 0.299 -0.005 3.72e-07 0.294 0.303 -0.010 9.68e-07
Height DBSLMM.PseudoVal LDpred1.Inf 0.332 0.299 0.034 3.49e-70 0.327 0.303 0.024 4.78e-10
Height lassosum.MultiPRS LDpred1.Inf 0.350 0.299 0.052 1.69e-15 0.348 0.303 0.045 5.14e-17
Height LDpred1.10FCVal LDpred1.Inf 0.300 0.299 0.001 4.80e-01 0.301 0.303 -0.002 4.29e-01
Height lassosum.PseudoVal LDpred1.Inf 0.285 0.299 -0.014 2.14e-03 0.281 0.303 -0.022 1.49e-02
Height LDpred2.10FCVal LDpred1.Inf 0.343 0.299 0.044 3.56e-114 0.346 0.303 0.042 7.90e-28
Height LDpred1.Inf LDpred1.10FCVal 0.299 0.300 -0.001 4.80e-01 0.303 0.301 0.002 4.29e-01
Height PRScs.MultiPRS LDpred1.10FCVal 0.347 0.300 0.048 2.94e-14 0.345 0.301 0.044 4.74e-19
Height LDpred1.10FCVal LDpred1.10FCVal 0.300 0.300 0.000 1.00e+00 0.301 0.301 0.000 1.00e+00
Height All.MultiPRS LDpred1.10FCVal 0.358 0.300 0.058 8.28e-21 0.361 0.301 0.060 5.55e-28
Height SBayesR.PseudoVal LDpred1.10FCVal 0.344 0.300 0.044 1.25e-39 0.343 0.301 0.042 3.56e-10
Height DBSLMM.PseudoVal LDpred1.10FCVal 0.332 0.300 0.033 8.02e-57 0.327 0.301 0.026 1.81e-10
Height pT+clump.MultiPRS LDpred1.10FCVal 0.320 0.300 0.020 2.27e-03 0.313 0.301 0.012 6.28e-02
Height lassosum.MultiPRS LDpred1.10FCVal 0.350 0.300 0.051 5.85e-15 0.348 0.301 0.047 1.35e-18
Height PRScs.10FCVal LDpred1.10FCVal 0.345 0.300 0.045 5.11e-66 0.344 0.301 0.043 8.49e-16
Height lassosum.PseudoVal LDpred1.10FCVal 0.285 0.300 -0.015 7.59e-04 0.281 0.301 -0.020 2.68e-02
Height SBLUP.Inf LDpred1.10FCVal 0.293 0.300 -0.006 4.58e-05 0.294 0.301 -0.007 1.51e-02
Height LDpred2.PseudoVal LDpred1.10FCVal 0.304 0.300 0.004 1.21e-02 0.304 0.301 0.003 4.30e-01
Height pT+clump.10FCVal LDpred1.10FCVal 0.304 0.300 0.005 2.42e-01 0.299 0.301 -0.002 7.79e-01
Height LDpred2.MultiPRS LDpred1.10FCVal 0.350 0.300 0.050 1.12e-14 0.354 0.301 0.053 3.39e-25
Height PRScs.PseudoVal LDpred1.10FCVal 0.346 0.300 0.046 1.46e-89 0.344 0.301 0.043 5.03e-20
Height LDpred2.10FCVal LDpred1.10FCVal 0.343 0.300 0.043 7.38e-96 0.346 0.301 0.045 3.02e-27
Height LDpred1.MultiPRS LDpred1.10FCVal 0.303 0.300 0.003 6.24e-01 0.307 0.301 0.006 1.77e-04
Height LDpred2.Inf LDpred1.10FCVal 0.305 0.300 0.005 3.51e-03 0.305 0.301 0.003 3.26e-01
Height lassosum.10FCVal LDpred1.10FCVal 0.347 0.300 0.048 3.10e-67 0.346 0.301 0.045 1.12e-15
Height LDpred1.Inf LDpred2.MultiPRS 0.299 0.350 -0.051 3.07e-15 0.303 0.354 -0.050 2.82e-23
Height DBSLMM.PseudoVal LDpred2.MultiPRS 0.332 0.350 -0.017 7.34e-03 0.327 0.354 -0.026 2.99e-12
Height SBLUP.Inf LDpred2.MultiPRS 0.293 0.350 -0.056 4.21e-18 0.294 0.354 -0.060 1.54e-30
Height LDpred2.Inf LDpred2.MultiPRS 0.305 0.350 -0.045 3.82e-12 0.305 0.354 -0.049 3.11e-25
Height pT+clump.10FCVal LDpred2.MultiPRS 0.304 0.350 -0.045 2.80e-12 0.299 0.354 -0.055 5.22e-20
Height LDpred2.10FCVal LDpred2.MultiPRS 0.343 0.350 -0.007 2.74e-01 0.346 0.354 -0.008 1.99e-05
Height PRScs.PseudoVal LDpred2.MultiPRS 0.346 0.350 -0.003 5.86e-01 0.344 0.354 -0.010 1.95e-04
Height LDpred1.10FCVal LDpred2.MultiPRS 0.300 0.350 -0.050 1.12e-14 0.301 0.354 -0.053 3.39e-25
Height All.MultiPRS LDpred2.MultiPRS 0.358 0.350 0.008 1.85e-01 0.361 0.354 0.007 1.45e-03
Height SBayesR.PseudoVal LDpred2.MultiPRS 0.344 0.350 -0.006 3.79e-01 0.343 0.354 -0.010 5.78e-03
Height lassosum.PseudoVal LDpred2.MultiPRS 0.285 0.350 -0.065 2.11e-23 0.281 0.354 -0.073 8.00e-31
Height pT+clump.MultiPRS LDpred2.MultiPRS 0.320 0.350 -0.030 3.28e-06 0.313 0.354 -0.041 2.79e-17
Height lassosum.MultiPRS LDpred2.MultiPRS 0.350 0.350 0.001 9.09e-01 0.348 0.354 -0.005 6.88e-02
Height PRScs.10FCVal LDpred2.MultiPRS 0.345 0.350 -0.004 4.83e-01 0.344 0.354 -0.010 4.16e-04
Height PRScs.MultiPRS LDpred2.MultiPRS 0.347 0.350 -0.002 7.06e-01 0.345 0.354 -0.008 1.11e-03
Height lassosum.10FCVal LDpred2.MultiPRS 0.347 0.350 -0.002 7.25e-01 0.346 0.354 -0.008 8.36e-03
Height LDpred2.PseudoVal LDpred2.MultiPRS 0.304 0.350 -0.046 1.77e-12 0.304 0.354 -0.050 1.98e-25
Height LDpred1.MultiPRS LDpred2.MultiPRS 0.303 0.350 -0.047 5.77e-13 0.307 0.354 -0.047 3.26e-22
Height LDpred2.MultiPRS LDpred2.MultiPRS 0.350 0.350 0.000 1.00e+00 0.354 0.354 0.000 1.00e+00
Height LDpred1.Inf LDpred2.10FCVal 0.299 0.343 -0.044 3.56e-114 0.303 0.346 -0.042 7.90e-28
Height PRScs.MultiPRS LDpred2.10FCVal 0.347 0.343 0.005 4.57e-01 0.345 0.346 -0.001 8.19e-01
Height LDpred2.MultiPRS LDpred2.10FCVal 0.350 0.343 0.007 2.74e-01 0.354 0.346 0.008 1.99e-05
Height PRScs.PseudoVal LDpred2.10FCVal 0.346 0.343 0.004 1.41e-02 0.344 0.346 -0.002 4.43e-01
Height LDpred2.10FCVal LDpred2.10FCVal 0.343 0.343 0.000 1.00e+00 0.346 0.346 0.000 1.00e+00
Height lassosum.MultiPRS LDpred2.10FCVal 0.350 0.343 0.008 2.27e-01 0.348 0.346 0.002 4.76e-01
Height LDpred1.10FCVal LDpred2.10FCVal 0.300 0.343 -0.043 7.38e-96 0.301 0.346 -0.045 3.02e-27
Height All.MultiPRS LDpred2.10FCVal 0.358 0.343 0.015 1.15e-02 0.361 0.346 0.015 2.57e-07
Height SBayesR.PseudoVal LDpred2.10FCVal 0.344 0.343 0.001 5.64e-01 0.343 0.346 -0.003 5.79e-01
Height DBSLMM.PseudoVal LDpred2.10FCVal 0.332 0.343 -0.010 8.04e-10 0.327 0.346 -0.019 2.03e-08
Height pT+clump.MultiPRS LDpred2.10FCVal 0.320 0.343 -0.023 3.75e-04 0.313 0.346 -0.033 2.63e-11
Height lassosum.10FCVal LDpred2.10FCVal 0.347 0.343 0.005 6.91e-03 0.346 0.346 0.000 9.23e-01
Height PRScs.10FCVal LDpred2.10FCVal 0.345 0.343 0.003 1.34e-01 0.344 0.346 -0.002 5.29e-01
Height lassosum.PseudoVal LDpred2.10FCVal 0.285 0.343 -0.058 1.10e-57 0.281 0.346 -0.065 4.47e-19
Height SBLUP.Inf LDpred2.10FCVal 0.293 0.343 -0.049 1.04e-131 0.294 0.346 -0.052 1.95e-38
Height LDpred2.PseudoVal LDpred2.10FCVal 0.304 0.343 -0.039 5.12e-120 0.304 0.346 -0.042 3.55e-36
Height pT+clump.10FCVal LDpred2.10FCVal 0.304 0.343 -0.038 1.51e-32 0.299 0.346 -0.047 2.55e-13
Height LDpred2.Inf LDpred2.10FCVal 0.305 0.343 -0.038 1.87e-116 0.305 0.346 -0.041 2.73e-35
Height LDpred1.MultiPRS LDpred2.10FCVal 0.303 0.343 -0.040 9.80e-10 0.307 0.346 -0.039 1.00e-25
Height lassosum.PseudoVal LDpred2.PseudoVal 0.285 0.304 -0.020 1.89e-05 0.281 0.304 -0.023 1.32e-02
Height SBLUP.Inf LDpred2.PseudoVal 0.293 0.304 -0.011 1.54e-21 0.294 0.304 -0.010 4.40e-06
Height SBayesR.PseudoVal LDpred2.PseudoVal 0.344 0.304 0.040 5.03e-32 0.343 0.304 0.040 7.25e-09
Height All.MultiPRS LDpred2.PseudoVal 0.358 0.304 0.054 3.80e-18 0.361 0.304 0.057 2.45e-27
Height PRScs.PseudoVal LDpred2.PseudoVal 0.346 0.304 0.042 1.81e-77 0.344 0.304 0.040 1.93e-18
Height lassosum.MultiPRS LDpred2.PseudoVal 0.350 0.304 0.046 9.16e-13 0.348 0.304 0.045 1.49e-16
Height PRScs.MultiPRS LDpred2.PseudoVal 0.347 0.304 0.043 4.39e-12 0.345 0.304 0.041 2.32e-17
Height LDpred2.MultiPRS LDpred2.PseudoVal 0.350 0.304 0.046 1.77e-12 0.354 0.304 0.050 1.98e-25
Height PRScs.10FCVal LDpred2.PseudoVal 0.345 0.304 0.041 7.38e-56 0.344 0.304 0.040 2.85e-14
Height LDpred2.PseudoVal LDpred2.PseudoVal 0.304 0.304 0.000 1.00e+00 0.304 0.304 0.000 1.00e+00
Height pT+clump.MultiPRS LDpred2.PseudoVal 0.320 0.304 0.016 1.68e-02 0.313 0.304 0.009 1.55e-01
Height pT+clump.10FCVal LDpred2.PseudoVal 0.304 0.304 0.000 9.50e-01 0.299 0.304 -0.005 5.30e-01
Height lassosum.10FCVal LDpred2.PseudoVal 0.347 0.304 0.043 6.26e-55 0.346 0.304 0.042 1.17e-13
Height LDpred1.Inf LDpred2.PseudoVal 0.299 0.304 -0.005 2.72e-06 0.303 0.304 0.000 8.80e-01
Height LDpred1.MultiPRS LDpred2.PseudoVal 0.303 0.304 -0.001 8.63e-01 0.307 0.304 0.003 2.62e-01
Height LDpred1.10FCVal LDpred2.PseudoVal 0.300 0.304 -0.004 1.21e-02 0.301 0.304 -0.003 4.30e-01
Height LDpred2.Inf LDpred2.PseudoVal 0.305 0.304 0.001 7.33e-07 0.305 0.304 0.001 1.95e-02
Height LDpred2.10FCVal LDpred2.PseudoVal 0.343 0.304 0.039 5.12e-120 0.346 0.304 0.042 3.55e-36
Height DBSLMM.PseudoVal LDpred2.PseudoVal 0.332 0.304 0.028 2.85e-47 0.327 0.304 0.024 2.29e-09
Height pT+clump.MultiPRS LDpred2.Inf 0.320 0.305 0.015 2.24e-02 0.313 0.305 0.008 1.83e-01
Height lassosum.MultiPRS LDpred2.Inf 0.350 0.305 0.046 2.00e-12 0.348 0.305 0.044 2.03e-16
Height SBayesR.PseudoVal LDpred2.Inf 0.344 0.305 0.039 1.71e-31 0.343 0.305 0.039 9.77e-09
Height All.MultiPRS LDpred2.Inf 0.358 0.305 0.053 1.00e-17 0.361 0.305 0.056 4.58e-27
Height SBLUP.Inf LDpred2.Inf 0.293 0.305 -0.011 2.10e-24 0.294 0.305 -0.011 9.43e-07
Height LDpred2.PseudoVal LDpred2.Inf 0.304 0.305 -0.001 7.33e-07 0.304 0.305 -0.001 1.95e-02
Height PRScs.MultiPRS LDpred2.Inf 0.347 0.305 0.042 9.55e-12 0.345 0.305 0.041 2.21e-17
Height LDpred2.MultiPRS LDpred2.Inf 0.350 0.305 0.045 3.82e-12 0.354 0.305 0.049 3.11e-25
Height PRScs.10FCVal LDpred2.Inf 0.345 0.305 0.040 8.18e-56 0.344 0.305 0.039 3.04e-14
Height LDpred1.Inf LDpred2.Inf 0.299 0.305 -0.006 6.28e-08 0.303 0.305 -0.001 6.51e-01
Height LDpred1.MultiPRS LDpred2.Inf 0.303 0.305 -0.002 7.79e-01 0.307 0.305 0.002 3.84e-01
Height pT+clump.10FCVal LDpred2.Inf 0.304 0.305 0.000 9.06e-01 0.299 0.305 -0.006 4.72e-01
Height lassosum.10FCVal LDpred2.Inf 0.347 0.305 0.043 3.03e-54 0.346 0.305 0.041 1.71e-13
Height PRScs.PseudoVal LDpred2.Inf 0.346 0.305 0.041 7.07e-78 0.344 0.305 0.039 1.77e-18
Height DBSLMM.PseudoVal LDpred2.Inf 0.332 0.305 0.028 9.47e-46 0.327 0.305 0.023 5.07e-09
Height LDpred1.10FCVal LDpred2.Inf 0.300 0.305 -0.005 3.51e-03 0.301 0.305 -0.003 3.26e-01
Height LDpred2.Inf LDpred2.Inf 0.305 0.305 0.000 1.00e+00 0.305 0.305 0.000 1.00e+00
Height lassosum.PseudoVal LDpred2.Inf 0.285 0.305 -0.020 8.20e-06 0.281 0.305 -0.023 1.02e-02
Height LDpred2.10FCVal LDpred2.Inf 0.343 0.305 0.038 1.87e-116 0.346 0.305 0.041 2.73e-35
Height PRScs.10FCVal PRScs.MultiPRS 0.345 0.347 -0.002 7.36e-01 0.344 0.345 -0.001 1.70e-01
Height LDpred1.10FCVal PRScs.MultiPRS 0.300 0.347 -0.048 2.94e-14 0.301 0.345 -0.044 4.74e-19
Height lassosum.MultiPRS PRScs.MultiPRS 0.350 0.347 0.003 6.20e-01 0.348 0.345 0.003 1.57e-01
Height LDpred2.MultiPRS PRScs.MultiPRS 0.350 0.347 0.002 7.06e-01 0.354 0.345 0.008 1.11e-03
Height All.MultiPRS PRScs.MultiPRS 0.358 0.347 0.011 1.64e-19 0.361 0.345 0.015 1.33e-10
Height PRScs.PseudoVal PRScs.MultiPRS 0.346 0.347 -0.001 8.63e-01 0.344 0.345 -0.001 5.64e-02
Height LDpred1.MultiPRS PRScs.MultiPRS 0.303 0.347 -0.044 7.02e-12 0.307 0.345 -0.039 1.96e-16
Height pT+clump.MultiPRS PRScs.MultiPRS 0.320 0.347 -0.028 2.02e-05 0.313 0.345 -0.033 1.39e-13
Height lassosum.10FCVal PRScs.MultiPRS 0.347 0.347 0.000 9.78e-01 0.346 0.345 0.000 8.93e-01
Height SBayesR.PseudoVal PRScs.MultiPRS 0.344 0.347 -0.003 6.00e-01 0.343 0.345 -0.002 5.97e-01
Height DBSLMM.PseudoVal PRScs.MultiPRS 0.332 0.347 -0.015 1.64e-02 0.327 0.345 -0.018 1.40e-08
Height SBLUP.Inf PRScs.MultiPRS 0.293 0.347 -0.054 8.25e-18 0.294 0.345 -0.052 2.04e-24
Height LDpred2.Inf PRScs.MultiPRS 0.305 0.347 -0.042 9.55e-12 0.305 0.345 -0.041 2.21e-17
Height pT+clump.10FCVal PRScs.MultiPRS 0.304 0.347 -0.043 6.41e-12 0.299 0.345 -0.046 1.53e-16
Height LDpred2.10FCVal PRScs.MultiPRS 0.343 0.347 -0.005 4.57e-01 0.346 0.345 0.001 8.19e-01
Height lassosum.PseudoVal PRScs.MultiPRS 0.285 0.347 -0.063 2.38e-23 0.281 0.345 -0.064 1.13e-28
Height LDpred2.PseudoVal PRScs.MultiPRS 0.304 0.347 -0.043 4.39e-12 0.304 0.345 -0.041 2.32e-17
Height LDpred1.Inf PRScs.MultiPRS 0.299 0.347 -0.049 7.23e-15 0.303 0.345 -0.042 7.00e-18
Height PRScs.MultiPRS PRScs.MultiPRS 0.347 0.347 0.000 1.00e+00 0.345 0.345 0.000 1.00e+00
Height LDpred2.PseudoVal PRScs.10FCVal 0.304 0.345 -0.041 7.38e-56 0.304 0.344 -0.040 2.85e-14
Height PRScs.10FCVal PRScs.10FCVal 0.345 0.345 0.000 1.00e+00 0.344 0.344 0.000 1.00e+00
Height LDpred2.MultiPRS PRScs.10FCVal 0.350 0.345 0.004 4.83e-01 0.354 0.344 0.010 4.16e-04
Height pT+clump.MultiPRS PRScs.10FCVal 0.320 0.345 -0.025 7.89e-05 0.313 0.344 -0.031 3.23e-12
Height LDpred1.Inf PRScs.10FCVal 0.299 0.345 -0.047 6.23e-71 0.303 0.344 -0.040 1.44e-14
Height LDpred1.MultiPRS PRScs.10FCVal 0.303 0.345 -0.042 7.93e-11 0.307 0.344 -0.037 2.87e-13
Height pT+clump.10FCVal PRScs.10FCVal 0.304 0.345 -0.041 1.14e-49 0.299 0.344 -0.045 5.99e-16
Height lassosum.10FCVal PRScs.10FCVal 0.347 0.345 0.002 1.04e-01 0.346 0.344 0.002 5.20e-01
Height PRScs.PseudoVal PRScs.10FCVal 0.346 0.345 0.001 2.57e-01 0.344 0.344 0.000 9.64e-01
Height DBSLMM.PseudoVal PRScs.10FCVal 0.332 0.345 -0.013 3.97e-13 0.327 0.344 -0.016 2.79e-06
Height SBLUP.Inf PRScs.10FCVal 0.293 0.345 -0.052 2.56e-80 0.294 0.344 -0.050 3.49e-20
Height LDpred2.Inf PRScs.10FCVal 0.305 0.345 -0.040 8.18e-56 0.305 0.344 -0.039 3.04e-14
Height lassosum.PseudoVal PRScs.10FCVal 0.285 0.345 -0.061 1.45e-106 0.281 0.344 -0.063 1.20e-29
Height LDpred2.10FCVal PRScs.10FCVal 0.343 0.345 -0.003 1.34e-01 0.346 0.344 0.002 5.29e-01
Height lassosum.MultiPRS PRScs.10FCVal 0.350 0.345 0.005 4.13e-01 0.348 0.344 0.005 5.36e-02
Height LDpred1.10FCVal PRScs.10FCVal 0.300 0.345 -0.045 5.11e-66 0.301 0.344 -0.043 8.49e-16
Height All.MultiPRS PRScs.10FCVal 0.358 0.345 0.013 3.43e-02 0.361 0.344 0.017 4.24e-11
Height SBayesR.PseudoVal PRScs.10FCVal 0.344 0.345 -0.001 5.11e-01 0.343 0.344 0.000 8.89e-01
Height PRScs.MultiPRS PRScs.10FCVal 0.347 0.345 0.002 7.36e-01 0.345 0.344 0.001 1.70e-01
Height All.MultiPRS PRScs.PseudoVal 0.358 0.346 0.012 5.07e-02 0.361 0.344 0.017 3.90e-11
Height pT+clump.MultiPRS PRScs.PseudoVal 0.320 0.346 -0.026 4.07e-05 0.313 0.344 -0.031 4.76e-12
Height LDpred2.PseudoVal PRScs.PseudoVal 0.304 0.346 -0.042 1.81e-77 0.304 0.344 -0.040 1.93e-18
Height SBayesR.PseudoVal PRScs.PseudoVal 0.344 0.346 -0.002 2.71e-01 0.343 0.344 0.000 9.17e-01
Height LDpred2.MultiPRS PRScs.PseudoVal 0.350 0.346 0.003 5.86e-01 0.354 0.344 0.010 1.95e-04
Height SBLUP.Inf PRScs.PseudoVal 0.293 0.346 -0.053 1.45e-111 0.294 0.344 -0.050 1.69e-26
Height LDpred1.Inf PRScs.PseudoVal 0.299 0.346 -0.048 1.85e-100 0.303 0.344 -0.040 3.43e-19
Height PRScs.10FCVal PRScs.PseudoVal 0.345 0.346 -0.001 2.57e-01 0.344 0.344 0.000 9.64e-01
Height LDpred2.Inf PRScs.PseudoVal 0.305 0.346 -0.041 7.07e-78 0.305 0.344 -0.039 1.77e-18
Height PRScs.PseudoVal PRScs.PseudoVal 0.346 0.346 0.000 1.00e+00 0.344 0.344 0.000 1.00e+00
Height LDpred2.10FCVal PRScs.PseudoVal 0.343 0.346 -0.004 1.41e-02 0.346 0.344 0.002 4.43e-01
Height pT+clump.10FCVal PRScs.PseudoVal 0.304 0.346 -0.042 1.05e-47 0.299 0.344 -0.045 1.11e-14
Height PRScs.MultiPRS PRScs.PseudoVal 0.347 0.346 0.001 8.63e-01 0.345 0.344 0.001 5.64e-02
Height lassosum.10FCVal PRScs.PseudoVal 0.347 0.346 0.001 3.69e-01 0.346 0.344 0.002 5.02e-01
Height lassosum.PseudoVal PRScs.PseudoVal 0.285 0.346 -0.062 6.18e-88 0.281 0.344 -0.063 6.85e-24
Height LDpred1.MultiPRS PRScs.PseudoVal 0.303 0.346 -0.043 2.77e-11 0.307 0.344 -0.037 1.52e-17
Height lassosum.MultiPRS PRScs.PseudoVal 0.350 0.346 0.004 5.09e-01 0.348 0.344 0.005 5.46e-02
Height LDpred1.10FCVal PRScs.PseudoVal 0.300 0.346 -0.046 1.46e-89 0.301 0.344 -0.043 5.03e-20
Height DBSLMM.PseudoVal PRScs.PseudoVal 0.332 0.346 -0.014 1.74e-20 0.327 0.344 -0.016 3.34e-08
Height All.MultiPRS pT+clump.MultiPRS 0.358 0.320 0.038 2.44e-09 0.361 0.313 0.048 2.13e-27
Height SBayesR.PseudoVal pT+clump.MultiPRS 0.344 0.320 0.024 1.67e-04 0.343 0.313 0.031 7.75e-10
Height LDpred1.MultiPRS pT+clump.MultiPRS 0.303 0.320 -0.017 1.05e-02 0.307 0.313 -0.006 3.22e-01
Height pT+clump.MultiPRS pT+clump.MultiPRS 0.320 0.320 0.000 1.00e+00 0.313 0.313 0.000 1.00e+00
Height lassosum.10FCVal pT+clump.MultiPRS 0.347 0.320 0.028 1.79e-05 0.346 0.313 0.033 2.93e-13
Height PRScs.10FCVal pT+clump.MultiPRS 0.345 0.320 0.025 7.89e-05 0.344 0.313 0.031 3.23e-12
Height DBSLMM.PseudoVal pT+clump.MultiPRS 0.332 0.320 0.013 4.90e-02 0.327 0.313 0.015 2.75e-03
Height SBLUP.Inf pT+clump.MultiPRS 0.293 0.320 -0.026 6.12e-05 0.294 0.313 -0.019 2.39e-03
Height LDpred2.Inf pT+clump.MultiPRS 0.305 0.320 -0.015 2.24e-02 0.305 0.313 -0.008 1.83e-01
Height pT+clump.10FCVal pT+clump.MultiPRS 0.304 0.320 -0.015 1.90e-02 0.299 0.313 -0.014 2.20e-06
Height LDpred2.10FCVal pT+clump.MultiPRS 0.343 0.320 0.023 3.75e-04 0.346 0.313 0.033 2.63e-11
Height PRScs.PseudoVal pT+clump.MultiPRS 0.346 0.320 0.026 4.07e-05 0.344 0.313 0.031 4.76e-12
Height LDpred1.10FCVal pT+clump.MultiPRS 0.300 0.320 -0.020 2.27e-03 0.301 0.313 -0.012 6.28e-02
Height LDpred1.Inf pT+clump.MultiPRS 0.299 0.320 -0.021 1.30e-03 0.303 0.313 -0.009 1.30e-01
Height PRScs.MultiPRS pT+clump.MultiPRS 0.347 0.320 0.028 2.02e-05 0.345 0.313 0.033 1.39e-13
Height lassosum.PseudoVal pT+clump.MultiPRS 0.285 0.320 -0.035 8.62e-08 0.281 0.313 -0.032 6.86e-06
Height LDpred2.PseudoVal pT+clump.MultiPRS 0.304 0.320 -0.016 1.68e-02 0.304 0.313 -0.009 1.55e-01
Height lassosum.MultiPRS pT+clump.MultiPRS 0.350 0.320 0.031 1.90e-06 0.348 0.313 0.036 6.06e-16
Height LDpred2.MultiPRS pT+clump.MultiPRS 0.350 0.320 0.030 3.28e-06 0.354 0.313 0.041 2.79e-17
Height LDpred2.10FCVal pT+clump.10FCVal 0.343 0.304 0.038 1.51e-32 0.346 0.299 0.047 2.55e-13
Height pT+clump.MultiPRS pT+clump.10FCVal 0.320 0.304 0.015 1.90e-02 0.313 0.299 0.014 2.20e-06
Height LDpred2.Inf pT+clump.10FCVal 0.305 0.304 0.000 9.06e-01 0.305 0.299 0.006 4.72e-01
Height SBayesR.PseudoVal pT+clump.10FCVal 0.344 0.304 0.040 8.80e-48 0.343 0.299 0.045 6.57e-16
Height PRScs.MultiPRS pT+clump.10FCVal 0.347 0.304 0.043 6.41e-12 0.345 0.299 0.046 1.53e-16
Height SBLUP.Inf pT+clump.10FCVal 0.293 0.304 -0.011 7.04e-03 0.294 0.299 -0.005 5.12e-01
Height lassosum.MultiPRS pT+clump.10FCVal 0.350 0.304 0.046 9.87e-13 0.348 0.299 0.050 8.33e-20
Height PRScs.10FCVal pT+clump.10FCVal 0.345 0.304 0.041 1.14e-49 0.344 0.299 0.045 5.99e-16
Height LDpred2.MultiPRS pT+clump.10FCVal 0.350 0.304 0.045 2.80e-12 0.354 0.299 0.055 5.22e-20
Height lassosum.PseudoVal pT+clump.10FCVal 0.285 0.304 -0.020 1.89e-08 0.281 0.299 -0.018 1.14e-02
Height LDpred2.PseudoVal pT+clump.10FCVal 0.304 0.304 0.000 9.50e-01 0.304 0.299 0.005 5.30e-01
Height LDpred1.MultiPRS pT+clump.10FCVal 0.303 0.304 -0.001 8.33e-01 0.307 0.299 0.008 3.07e-01
Height pT+clump.10FCVal pT+clump.10FCVal 0.304 0.304 0.000 1.00e+00 0.299 0.299 0.000 1.00e+00
Height All.MultiPRS pT+clump.10FCVal 0.358 0.304 0.054 5.46e-18 0.361 0.299 0.062 2.85e-32
Height LDpred1.Inf pT+clump.10FCVal 0.299 0.304 -0.006 1.48e-01 0.303 0.299 0.005 5.56e-01
Height DBSLMM.PseudoVal pT+clump.10FCVal 0.332 0.304 0.028 2.05e-18 0.327 0.299 0.029 9.51e-06
Height LDpred1.10FCVal pT+clump.10FCVal 0.300 0.304 -0.005 2.42e-01 0.301 0.299 0.002 7.79e-01
Height lassosum.10FCVal pT+clump.10FCVal 0.347 0.304 0.043 7.92e-53 0.346 0.299 0.047 1.39e-16
Height PRScs.PseudoVal pT+clump.10FCVal 0.346 0.304 0.042 1.05e-47 0.344 0.299 0.045 1.11e-14
Height pT+clump.MultiPRS SBayesR.PseudoVal 0.320 0.344 -0.024 1.67e-04 0.313 0.343 -0.031 7.75e-10
Height LDpred1.10FCVal SBayesR.PseudoVal 0.300 0.344 -0.044 1.25e-39 0.301 0.343 -0.042 3.56e-10
Height PRScs.10FCVal SBayesR.PseudoVal 0.345 0.344 0.001 5.11e-01 0.344 0.343 0.000 8.89e-01
Height LDpred2.10FCVal SBayesR.PseudoVal 0.343 0.344 -0.001 5.64e-01 0.346 0.343 0.003 5.79e-01
Height lassosum.PseudoVal SBayesR.PseudoVal 0.285 0.344 -0.059 1.17e-107 0.281 0.343 -0.062 7.00e-31
Height LDpred2.PseudoVal SBayesR.PseudoVal 0.304 0.344 -0.040 5.03e-32 0.304 0.343 -0.040 7.25e-09
Height lassosum.MultiPRS SBayesR.PseudoVal 0.350 0.344 0.006 3.17e-01 0.348 0.343 0.005 1.60e-01
Height LDpred2.MultiPRS SBayesR.PseudoVal 0.350 0.344 0.006 3.79e-01 0.354 0.343 0.010 5.78e-03
Height All.MultiPRS SBayesR.PseudoVal 0.358 0.344 0.014 2.11e-02 0.361 0.343 0.017 2.98e-10
Height PRScs.PseudoVal SBayesR.PseudoVal 0.346 0.344 0.002 2.71e-01 0.344 0.343 0.000 9.17e-01
Height LDpred1.MultiPRS SBayesR.PseudoVal 0.303 0.344 -0.041 2.48e-10 0.307 0.343 -0.037 3.49e-08
Height pT+clump.10FCVal SBayesR.PseudoVal 0.304 0.344 -0.040 8.80e-48 0.299 0.343 -0.045 6.57e-16
Height lassosum.10FCVal SBayesR.PseudoVal 0.347 0.344 0.003 8.62e-02 0.346 0.343 0.002 5.64e-01
Height SBayesR.PseudoVal SBayesR.PseudoVal 0.344 0.344 0.000 1.00e+00 0.343 0.343 0.000 1.00e+00
Height DBSLMM.PseudoVal SBayesR.PseudoVal 0.332 0.344 -0.012 2.45e-06 0.327 0.343 -0.016 1.18e-03
Height SBLUP.Inf SBayesR.PseudoVal 0.293 0.344 -0.051 2.83e-47 0.294 0.343 -0.050 1.32e-12
Height LDpred2.Inf SBayesR.PseudoVal 0.305 0.344 -0.039 1.71e-31 0.305 0.343 -0.039 9.77e-09
Height LDpred1.Inf SBayesR.PseudoVal 0.299 0.344 -0.045 1.85e-40 0.303 0.343 -0.040 5.63e-09
Height PRScs.MultiPRS SBayesR.PseudoVal 0.347 0.344 0.003 6.00e-01 0.345 0.343 0.002 5.97e-01
Height LDpred2.10FCVal SBLUP.Inf 0.343 0.293 0.049 1.04e-131 0.346 0.294 0.052 1.95e-38
Height PRScs.PseudoVal SBLUP.Inf 0.346 0.293 0.053 1.45e-111 0.344 0.294 0.050 1.69e-26
Height LDpred1.10FCVal SBLUP.Inf 0.300 0.293 0.006 4.58e-05 0.301 0.294 0.007 1.51e-02
Height LDpred2.Inf SBLUP.Inf 0.305 0.293 0.011 2.10e-24 0.305 0.294 0.011 9.43e-07
Height SBayesR.PseudoVal SBLUP.Inf 0.344 0.293 0.051 2.83e-47 0.343 0.294 0.050 1.32e-12
Height lassosum.PseudoVal SBLUP.Inf 0.285 0.293 -0.009 5.90e-02 0.281 0.294 -0.013 1.85e-01
Height pT+clump.MultiPRS SBLUP.Inf 0.320 0.293 0.026 6.12e-05 0.313 0.294 0.019 2.39e-03
Height lassosum.MultiPRS SBLUP.Inf 0.350 0.293 0.057 2.04e-18 0.348 0.294 0.055 2.87e-23
Height PRScs.10FCVal SBLUP.Inf 0.345 0.293 0.052 2.56e-80 0.344 0.294 0.050 3.49e-20
Height PRScs.MultiPRS SBLUP.Inf 0.347 0.293 0.054 8.25e-18 0.345 0.294 0.052 2.04e-24
Height LDpred1.MultiPRS SBLUP.Inf 0.303 0.293 0.009 1.49e-01 0.307 0.294 0.013 1.97e-09
Height LDpred2.PseudoVal SBLUP.Inf 0.304 0.293 0.011 1.54e-21 0.304 0.294 0.010 4.40e-06
Height LDpred1.Inf SBLUP.Inf 0.299 0.293 0.005 3.72e-07 0.303 0.294 0.010 9.68e-07
Height LDpred2.MultiPRS SBLUP.Inf 0.350 0.293 0.056 4.21e-18 0.354 0.294 0.060 1.54e-30
Height All.MultiPRS SBLUP.Inf 0.358 0.293 0.065 4.37e-25 0.361 0.294 0.067 1.41e-32
Height SBLUP.Inf SBLUP.Inf 0.293 0.293 0.000 1.00e+00 0.294 0.294 0.000 1.00e+00
Height DBSLMM.PseudoVal SBLUP.Inf 0.332 0.293 0.039 9.41e-91 0.327 0.294 0.034 1.65e-18
Height pT+clump.10FCVal SBLUP.Inf 0.304 0.293 0.011 7.04e-03 0.299 0.294 0.005 5.12e-01
Height lassosum.10FCVal SBLUP.Inf 0.347 0.293 0.054 1.09e-80 0.346 0.294 0.052 1.12e-19
BMI LDpred2.PseudoVal All.MultiPRS 0.256 0.307 -0.050 3.99e-14 0.261 0.305 -0.044 2.93e-15
BMI pT+clump.10FCVal All.MultiPRS 0.249 0.307 -0.058 2.54e-18 0.244 0.305 -0.061 2.24e-26
BMI LDpred2.MultiPRS All.MultiPRS 0.302 0.307 -0.004 4.96e-01 0.299 0.305 -0.006 3.94e-04
BMI PRScs.PseudoVal All.MultiPRS 0.282 0.307 -0.024 2.41e-04 0.282 0.305 -0.023 2.68e-09
BMI LDpred1.Inf All.MultiPRS 0.274 0.307 -0.032 1.15e-06 0.264 0.305 -0.041 7.32e-21
BMI PRScs.MultiPRS All.MultiPRS 0.301 0.307 -0.005 4.21e-01 0.296 0.305 -0.009 2.83e-07
BMI LDpred2.Inf All.MultiPRS 0.291 0.307 -0.015 1.90e-02 0.284 0.305 -0.021 6.88e-12
BMI lassosum.10FCVal All.MultiPRS 0.300 0.307 -0.006 3.47e-01 0.298 0.305 -0.007 3.42e-04
BMI LDpred2.10FCVal All.MultiPRS 0.301 0.307 -0.005 4.39e-01 0.296 0.305 -0.009 2.20e-07
BMI lassosum.MultiPRS All.MultiPRS 0.305 0.307 -0.002 7.73e-01 0.305 0.305 0.000 8.84e-01
BMI LDpred1.10FCVal All.MultiPRS 0.279 0.307 -0.028 2.31e-05 0.271 0.305 -0.034 1.93e-16
BMI All.MultiPRS All.MultiPRS 0.307 0.307 0.000 1.00e+00 0.305 0.305 0.000 1.00e+00
BMI SBayesR.PseudoVal All.MultiPRS 0.211 0.307 -0.095 1.34e-45 0.224 0.305 -0.081 7.00e-27
BMI LDpred1.MultiPRS All.MultiPRS 0.289 0.307 -0.018 6.81e-03 0.281 0.305 -0.024 1.16e-12
BMI pT+clump.MultiPRS All.MultiPRS 0.271 0.307 -0.036 7.60e-08 0.274 0.305 -0.031 2.37e-12
BMI lassosum.PseudoVal All.MultiPRS 0.216 0.307 -0.091 8.15e-42 0.225 0.305 -0.080 5.47e-27
BMI PRScs.10FCVal All.MultiPRS 0.292 0.307 -0.015 2.62e-02 0.282 0.305 -0.024 2.66e-15
BMI DBSLMM.PseudoVal All.MultiPRS 0.285 0.307 -0.022 8.66e-04 0.283 0.305 -0.022 2.31e-09
BMI SBLUP.Inf All.MultiPRS 0.293 0.307 -0.014 3.30e-02 0.286 0.305 -0.019 4.50e-11
BMI SBayesR.PseudoVal DBSLMM.PseudoVal 0.211 0.285 -0.073 6.58e-118 0.224 0.283 -0.059 7.93e-21
BMI LDpred2.Inf DBSLMM.PseudoVal 0.291 0.285 0.007 9.40e-03 0.284 0.283 0.001 8.05e-01
BMI pT+clump.10FCVal DBSLMM.PseudoVal 0.249 0.285 -0.036 9.11e-24 0.244 0.283 -0.039 1.02e-07
BMI PRScs.10FCVal DBSLMM.PseudoVal 0.292 0.285 0.007 2.41e-03 0.282 0.283 -0.001 7.74e-01
BMI PRScs.PseudoVal DBSLMM.PseudoVal 0.282 0.285 -0.002 1.91e-01 0.282 0.283 -0.001 7.51e-01
BMI pT+clump.MultiPRS DBSLMM.PseudoVal 0.271 0.285 -0.014 4.17e-02 0.274 0.283 -0.009 9.36e-02
BMI LDpred1.Inf DBSLMM.PseudoVal 0.274 0.285 -0.010 2.10e-04 0.264 0.283 -0.019 7.09e-04
BMI lassosum.MultiPRS DBSLMM.PseudoVal 0.305 0.285 0.020 2.38e-03 0.305 0.283 0.022 9.20e-08
BMI LDpred2.10FCVal DBSLMM.PseudoVal 0.301 0.285 0.017 1.43e-17 0.296 0.283 0.013 1.31e-03
BMI lassosum.10FCVal DBSLMM.PseudoVal 0.300 0.285 0.016 2.77e-12 0.298 0.283 0.015 1.04e-03
BMI LDpred1.10FCVal DBSLMM.PseudoVal 0.279 0.285 -0.006 4.46e-03 0.271 0.283 -0.012 6.86e-03
BMI LDpred1.MultiPRS DBSLMM.PseudoVal 0.289 0.285 0.004 5.38e-01 0.281 0.283 -0.002 6.32e-01
BMI PRScs.MultiPRS DBSLMM.PseudoVal 0.301 0.285 0.017 1.16e-02 0.296 0.283 0.013 5.21e-04
BMI All.MultiPRS DBSLMM.PseudoVal 0.307 0.285 0.022 8.66e-04 0.305 0.283 0.022 2.31e-09
BMI LDpred2.PseudoVal DBSLMM.PseudoVal 0.256 0.285 -0.028 3.12e-26 0.261 0.283 -0.022 5.11e-05
BMI DBSLMM.PseudoVal DBSLMM.PseudoVal 0.285 0.285 0.000 1.00e+00 0.283 0.283 0.000 1.00e+00
BMI LDpred2.MultiPRS DBSLMM.PseudoVal 0.302 0.285 0.017 8.02e-03 0.299 0.283 0.016 4.64e-05
BMI lassosum.PseudoVal DBSLMM.PseudoVal 0.216 0.285 -0.069 3.28e-99 0.225 0.283 -0.058 7.97e-19
BMI SBLUP.Inf DBSLMM.PseudoVal 0.293 0.285 0.008 1.44e-03 0.286 0.283 0.003 5.94e-01
BMI SBayesR.PseudoVal lassosum.MultiPRS 0.211 0.305 -0.093 5.75e-44 0.224 0.305 -0.081 1.44e-25
BMI LDpred2.10FCVal lassosum.MultiPRS 0.301 0.305 -0.003 6.27e-01 0.296 0.305 -0.009 1.01e-03
BMI LDpred1.10FCVal lassosum.MultiPRS 0.279 0.305 -0.026 7.75e-05 0.271 0.305 -0.034 4.14e-13
BMI LDpred2.Inf lassosum.MultiPRS 0.291 0.305 -0.014 3.98e-02 0.284 0.305 -0.021 1.34e-08
BMI PRScs.10FCVal lassosum.MultiPRS 0.292 0.305 -0.013 5.32e-02 0.282 0.305 -0.023 8.25e-12
BMI PRScs.MultiPRS lassosum.MultiPRS 0.301 0.305 -0.003 6.04e-01 0.296 0.305 -0.009 3.02e-04
BMI pT+clump.MultiPRS lassosum.MultiPRS 0.271 0.305 -0.034 3.77e-07 0.274 0.305 -0.031 4.02e-11
BMI lassosum.MultiPRS lassosum.MultiPRS 0.305 0.305 0.000 1.00e+00 0.305 0.305 0.000 1.00e+00
BMI lassosum.PseudoVal lassosum.MultiPRS 0.216 0.305 -0.089 2.62e-40 0.225 0.305 -0.080 5.19e-27
BMI LDpred2.MultiPRS lassosum.MultiPRS 0.302 0.305 -0.003 6.94e-01 0.299 0.305 -0.006 2.85e-02
BMI LDpred1.MultiPRS lassosum.MultiPRS 0.289 0.305 -0.016 1.56e-02 0.281 0.305 -0.024 1.98e-09
BMI LDpred2.PseudoVal lassosum.MultiPRS 0.256 0.305 -0.048 3.28e-13 0.261 0.305 -0.044 1.18e-13
BMI LDpred1.Inf lassosum.MultiPRS 0.274 0.305 -0.030 4.73e-06 0.264 0.305 -0.041 3.69e-17
BMI pT+clump.10FCVal lassosum.MultiPRS 0.249 0.305 -0.056 4.19e-17 0.244 0.305 -0.061 6.01e-25
BMI lassosum.10FCVal lassosum.MultiPRS 0.300 0.305 -0.004 5.14e-01 0.298 0.305 -0.007 8.18e-05
BMI SBLUP.Inf lassosum.MultiPRS 0.293 0.305 -0.012 6.56e-02 0.286 0.305 -0.019 2.91e-08
BMI DBSLMM.PseudoVal lassosum.MultiPRS 0.285 0.305 -0.020 2.38e-03 0.283 0.305 -0.022 9.20e-08
BMI All.MultiPRS lassosum.MultiPRS 0.307 0.305 0.002 7.73e-01 0.305 0.305 0.000 8.84e-01
BMI PRScs.PseudoVal lassosum.MultiPRS 0.282 0.305 -0.022 7.11e-04 0.282 0.305 -0.023 1.08e-07
BMI LDpred1.Inf lassosum.PseudoVal 0.274 0.216 0.059 3.28e-40 0.264 0.225 0.039 1.48e-05
BMI PRScs.10FCVal lassosum.PseudoVal 0.292 0.216 0.076 2.00e-64 0.282 0.225 0.057 3.90e-10
BMI LDpred2.MultiPRS lassosum.PseudoVal 0.302 0.216 0.086 8.31e-38 0.299 0.225 0.074 2.02e-22
BMI lassosum.PseudoVal lassosum.PseudoVal 0.216 0.216 0.000 1.00e+00 0.225 0.225 0.000 1.00e+00
BMI PRScs.PseudoVal lassosum.PseudoVal 0.282 0.216 0.067 9.48e-133 0.282 0.225 0.057 3.33e-25
BMI DBSLMM.PseudoVal lassosum.PseudoVal 0.285 0.216 0.069 3.28e-99 0.283 0.225 0.058 7.97e-19
BMI SBLUP.Inf lassosum.PseudoVal 0.293 0.216 0.077 1.34e-60 0.286 0.225 0.061 1.28e-10
BMI LDpred2.Inf lassosum.PseudoVal 0.291 0.216 0.075 4.85e-59 0.284 0.225 0.059 3.09e-10
BMI pT+clump.10FCVal lassosum.PseudoVal 0.249 0.216 0.033 1.27e-11 0.244 0.225 0.019 5.37e-02
BMI LDpred2.10FCVal lassosum.PseudoVal 0.301 0.216 0.086 9.23e-109 0.296 0.225 0.071 1.69e-19
BMI lassosum.MultiPRS lassosum.PseudoVal 0.305 0.216 0.089 2.62e-40 0.305 0.225 0.080 5.19e-27
BMI LDpred1.10FCVal lassosum.PseudoVal 0.279 0.216 0.063 5.17e-94 0.271 0.225 0.046 9.26e-14
BMI All.MultiPRS lassosum.PseudoVal 0.307 0.216 0.091 8.15e-42 0.305 0.225 0.080 5.47e-27
BMI SBayesR.PseudoVal lassosum.PseudoVal 0.211 0.216 -0.004 1.10e-01 0.224 0.225 -0.001 8.44e-01
BMI lassosum.10FCVal lassosum.PseudoVal 0.300 0.216 0.085 1.13e-99 0.298 0.225 0.073 1.77e-19
BMI pT+clump.MultiPRS lassosum.PseudoVal 0.271 0.216 0.055 3.91e-16 0.274 0.225 0.049 3.37e-10
BMI LDpred2.PseudoVal lassosum.PseudoVal 0.256 0.216 0.041 8.43e-81 0.261 0.225 0.036 4.15e-17
BMI LDpred1.MultiPRS lassosum.PseudoVal 0.289 0.216 0.073 1.48e-27 0.281 0.225 0.056 3.22e-15
BMI PRScs.MultiPRS lassosum.PseudoVal 0.301 0.216 0.085 1.97e-37 0.296 0.225 0.071 1.32e-20
BMI lassosum.10FCVal lassosum.10FCVal 0.300 0.300 0.000 1.00e+00 0.298 0.298 0.000 1.00e+00
BMI pT+clump.MultiPRS lassosum.10FCVal 0.271 0.300 -0.029 9.78e-06 0.274 0.298 -0.024 1.37e-06
BMI LDpred2.Inf lassosum.10FCVal 0.291 0.300 -0.009 2.07e-09 0.284 0.298 -0.014 1.01e-05
BMI SBayesR.PseudoVal lassosum.10FCVal 0.211 0.300 -0.089 9.78e-100 0.224 0.298 -0.074 1.52e-18
BMI PRScs.MultiPRS lassosum.10FCVal 0.301 0.300 0.001 8.93e-01 0.296 0.298 -0.002 3.71e-01
BMI SBLUP.Inf lassosum.10FCVal 0.293 0.300 -0.008 1.15e-07 0.286 0.298 -0.012 3.01e-05
BMI lassosum.MultiPRS lassosum.10FCVal 0.305 0.300 0.004 5.14e-01 0.305 0.298 0.007 8.18e-05
BMI PRScs.10FCVal lassosum.10FCVal 0.292 0.300 -0.008 1.71e-07 0.282 0.298 -0.016 3.45e-07
BMI LDpred2.MultiPRS lassosum.10FCVal 0.302 0.300 0.002 7.95e-01 0.299 0.298 0.001 7.13e-01
BMI PRScs.PseudoVal lassosum.10FCVal 0.282 0.300 -0.018 2.39e-15 0.282 0.298 -0.016 4.95e-04
BMI LDpred2.PseudoVal lassosum.10FCVal 0.256 0.300 -0.044 4.85e-42 0.261 0.298 -0.037 2.53e-08
BMI LDpred1.MultiPRS lassosum.10FCVal 0.289 0.300 -0.012 7.66e-02 0.281 0.298 -0.017 3.04e-05
BMI pT+clump.10FCVal lassosum.10FCVal 0.249 0.300 -0.052 6.29e-69 0.244 0.298 -0.054 6.65e-20
BMI All.MultiPRS lassosum.10FCVal 0.307 0.300 0.006 3.47e-01 0.305 0.298 0.007 3.42e-04
BMI LDpred1.Inf lassosum.10FCVal 0.274 0.300 -0.026 1.56e-33 0.264 0.298 -0.034 7.84e-15
BMI DBSLMM.PseudoVal lassosum.10FCVal 0.285 0.300 -0.016 2.77e-12 0.283 0.298 -0.015 1.04e-03
BMI LDpred1.10FCVal lassosum.10FCVal 0.279 0.300 -0.022 1.97e-21 0.271 0.298 -0.027 1.10e-08
BMI lassosum.PseudoVal lassosum.10FCVal 0.216 0.300 -0.085 1.13e-99 0.225 0.298 -0.073 1.77e-19
BMI LDpred2.10FCVal lassosum.10FCVal 0.301 0.300 0.001 4.36e-01 0.296 0.298 -0.002 4.24e-01
BMI LDpred2.10FCVal LDpred1.MultiPRS 0.301 0.289 0.013 5.23e-02 0.296 0.281 0.015 1.03e-04
BMI PRScs.PseudoVal LDpred1.MultiPRS 0.282 0.289 -0.006 3.36e-01 0.282 0.281 0.001 8.11e-01
BMI LDpred2.Inf LDpred1.MultiPRS 0.291 0.289 0.002 7.13e-01 0.284 0.281 0.003 4.59e-01
BMI pT+clump.10FCVal LDpred1.MultiPRS 0.249 0.289 -0.040 2.05e-09 0.244 0.281 -0.037 1.49e-07
BMI SBayesR.PseudoVal LDpred1.MultiPRS 0.211 0.289 -0.077 1.36e-30 0.224 0.281 -0.057 8.42e-15
BMI All.MultiPRS LDpred1.MultiPRS 0.307 0.289 0.018 6.81e-03 0.305 0.281 0.024 1.16e-12
BMI LDpred1.10FCVal LDpred1.MultiPRS 0.279 0.289 -0.010 1.27e-01 0.271 0.281 -0.010 9.11e-05
BMI LDpred1.MultiPRS LDpred1.MultiPRS 0.289 0.289 0.000 1.00e+00 0.281 0.281 0.000 1.00e+00
BMI PRScs.10FCVal LDpred1.MultiPRS 0.292 0.289 0.003 6.23e-01 0.282 0.281 0.001 8.88e-01
BMI lassosum.PseudoVal LDpred1.MultiPRS 0.216 0.289 -0.073 1.48e-27 0.225 0.281 -0.056 3.22e-15
BMI pT+clump.MultiPRS LDpred1.MultiPRS 0.271 0.289 -0.018 8.03e-03 0.274 0.281 -0.007 2.00e-01
BMI LDpred1.Inf LDpred1.MultiPRS 0.274 0.289 -0.014 3.12e-02 0.264 0.281 -0.017 1.39e-08
BMI lassosum.MultiPRS LDpred1.MultiPRS 0.305 0.289 0.016 1.56e-02 0.305 0.281 0.024 1.98e-09
BMI PRScs.MultiPRS LDpred1.MultiPRS 0.301 0.289 0.013 1.68e-11 0.296 0.281 0.015 8.41e-05
BMI lassosum.10FCVal LDpred1.MultiPRS 0.300 0.289 0.012 7.66e-02 0.298 0.281 0.017 3.04e-05
BMI LDpred2.PseudoVal LDpred1.MultiPRS 0.256 0.289 -0.032 1.18e-06 0.261 0.281 -0.020 3.79e-04
BMI DBSLMM.PseudoVal LDpred1.MultiPRS 0.285 0.289 -0.004 5.38e-01 0.283 0.281 0.002 6.32e-01
BMI LDpred2.MultiPRS LDpred1.MultiPRS 0.302 0.289 0.013 4.22e-02 0.299 0.281 0.018 6.82e-07
BMI SBLUP.Inf LDpred1.MultiPRS 0.293 0.289 0.004 5.61e-01 0.286 0.281 0.005 2.89e-01
BMI All.MultiPRS LDpred1.Inf 0.307 0.274 0.032 1.15e-06 0.305 0.264 0.041 7.32e-21
BMI LDpred2.PseudoVal LDpred1.Inf 0.256 0.274 -0.018 1.50e-06 0.261 0.264 -0.003 7.32e-01
BMI SBayesR.PseudoVal LDpred1.Inf 0.211 0.274 -0.063 3.89e-43 0.224 0.264 -0.040 1.51e-05
BMI LDpred2.MultiPRS LDpred1.Inf 0.302 0.274 0.028 2.73e-05 0.299 0.264 0.035 6.60e-15
BMI PRScs.PseudoVal LDpred1.Inf 0.282 0.274 0.008 3.92e-03 0.282 0.264 0.018 1.33e-03
BMI LDpred1.Inf LDpred1.Inf 0.274 0.274 0.000 1.00e+00 0.264 0.264 0.000 1.00e+00
BMI pT+clump.10FCVal LDpred1.Inf 0.249 0.274 -0.026 2.12e-13 0.244 0.264 -0.020 5.30e-03
BMI PRScs.MultiPRS LDpred1.Inf 0.301 0.274 0.027 4.87e-05 0.296 0.264 0.032 3.29e-13
BMI lassosum.PseudoVal LDpred1.Inf 0.216 0.274 -0.059 3.28e-40 0.225 0.264 -0.039 1.48e-05
BMI pT+clump.MultiPRS LDpred1.Inf 0.271 0.274 -0.003 6.17e-01 0.274 0.264 0.010 1.15e-01
BMI LDpred1.MultiPRS LDpred1.Inf 0.289 0.274 0.014 3.12e-02 0.281 0.264 0.017 1.39e-08
BMI PRScs.10FCVal LDpred1.Inf 0.292 0.274 0.018 8.76e-13 0.282 0.264 0.018 3.37e-04
BMI LDpred2.Inf LDpred1.Inf 0.291 0.274 0.017 8.77e-18 0.284 0.264 0.020 2.85e-07
BMI SBLUP.Inf LDpred1.Inf 0.293 0.274 0.018 6.95e-21 0.286 0.264 0.022 3.52e-08
BMI DBSLMM.PseudoVal LDpred1.Inf 0.285 0.274 0.010 2.10e-04 0.283 0.264 0.019 7.09e-04
BMI lassosum.MultiPRS LDpred1.Inf 0.305 0.274 0.030 4.73e-06 0.305 0.264 0.041 3.69e-17
BMI LDpred1.10FCVal LDpred1.Inf 0.279 0.274 0.004 3.00e-02 0.271 0.264 0.007 5.85e-02
BMI lassosum.10FCVal LDpred1.Inf 0.300 0.274 0.026 1.56e-33 0.298 0.264 0.034 7.84e-15
BMI LDpred2.10FCVal LDpred1.Inf 0.301 0.274 0.027 3.02e-35 0.296 0.264 0.032 8.61e-13
BMI LDpred1.Inf LDpred1.10FCVal 0.274 0.279 -0.004 3.00e-02 0.264 0.271 -0.007 5.85e-02
BMI PRScs.MultiPRS LDpred1.10FCVal 0.301 0.279 0.023 5.93e-04 0.296 0.271 0.024 3.94e-09
BMI LDpred1.10FCVal LDpred1.10FCVal 0.279 0.279 0.000 1.00e+00 0.271 0.271 0.000 1.00e+00
BMI All.MultiPRS LDpred1.10FCVal 0.307 0.279 0.028 2.31e-05 0.305 0.271 0.034 1.93e-16
BMI SBayesR.PseudoVal LDpred1.10FCVal 0.211 0.279 -0.067 4.00e-81 0.224 0.271 -0.047 2.08e-11
BMI DBSLMM.PseudoVal LDpred1.10FCVal 0.285 0.279 0.006 4.46e-03 0.283 0.271 0.012 6.86e-03
BMI pT+clump.MultiPRS LDpred1.10FCVal 0.271 0.279 -0.008 2.60e-01 0.274 0.271 0.002 6.78e-01
BMI lassosum.MultiPRS LDpred1.10FCVal 0.305 0.279 0.026 7.75e-05 0.305 0.271 0.034 4.14e-13
BMI PRScs.10FCVal LDpred1.10FCVal 0.292 0.279 0.013 1.50e-06 0.282 0.271 0.010 6.51e-02
BMI lassosum.10FCVal LDpred1.10FCVal 0.300 0.279 0.022 1.97e-21 0.298 0.271 0.027 1.10e-08
BMI SBLUP.Inf LDpred1.10FCVal 0.293 0.279 0.014 1.93e-07 0.286 0.271 0.014 8.23e-03
BMI LDpred2.PseudoVal LDpred1.10FCVal 0.256 0.279 -0.022 9.05e-18 0.261 0.271 -0.010 5.67e-02
BMI pT+clump.10FCVal LDpred1.10FCVal 0.249 0.279 -0.030 5.32e-16 0.244 0.271 -0.027 2.79e-04
BMI LDpred2.MultiPRS LDpred1.10FCVal 0.302 0.279 0.024 3.64e-04 0.299 0.271 0.028 7.85e-11
BMI PRScs.PseudoVal LDpred1.10FCVal 0.282 0.279 0.004 3.05e-02 0.282 0.271 0.011 2.85e-03
BMI LDpred2.10FCVal LDpred1.10FCVal 0.301 0.279 0.023 4.56e-27 0.296 0.271 0.024 1.52e-08
BMI LDpred1.MultiPRS LDpred1.10FCVal 0.289 0.279 0.010 1.27e-01 0.281 0.271 0.010 9.11e-05
BMI LDpred2.Inf LDpred1.10FCVal 0.291 0.279 0.013 2.67e-06 0.284 0.271 0.013 1.73e-02
BMI lassosum.PseudoVal LDpred1.10FCVal 0.216 0.279 -0.063 5.17e-94 0.225 0.271 -0.046 9.26e-14
BMI LDpred1.Inf LDpred2.MultiPRS 0.274 0.302 -0.028 2.73e-05 0.264 0.299 -0.035 6.60e-15
BMI DBSLMM.PseudoVal LDpred2.MultiPRS 0.285 0.302 -0.017 8.02e-03 0.283 0.299 -0.016 4.64e-05
BMI SBLUP.Inf LDpred2.MultiPRS 0.293 0.302 -0.010 1.47e-01 0.286 0.299 -0.013 1.63e-05
BMI LDpred2.Inf LDpred2.MultiPRS 0.291 0.302 -0.011 9.56e-02 0.284 0.299 -0.015 7.18e-08
BMI pT+clump.10FCVal LDpred2.MultiPRS 0.249 0.302 -0.053 9.71e-16 0.244 0.299 -0.055 9.79e-19
BMI LDpred2.10FCVal LDpred2.MultiPRS 0.301 0.302 -0.001 9.26e-01 0.296 0.299 -0.003 3.91e-03
BMI PRScs.PseudoVal LDpred2.MultiPRS 0.282 0.302 -0.020 2.74e-03 0.282 0.299 -0.017 3.98e-05
BMI LDpred1.10FCVal LDpred2.MultiPRS 0.279 0.302 -0.024 3.64e-04 0.271 0.299 -0.028 7.85e-11
BMI All.MultiPRS LDpred2.MultiPRS 0.307 0.302 0.004 4.96e-01 0.305 0.299 0.006 3.94e-04
BMI SBayesR.PseudoVal LDpred2.MultiPRS 0.211 0.302 -0.091 9.68e-42 0.224 0.299 -0.075 6.96e-23
BMI lassosum.10FCVal LDpred2.MultiPRS 0.300 0.302 -0.002 7.95e-01 0.298 0.299 -0.001 7.13e-01
BMI pT+clump.MultiPRS LDpred2.MultiPRS 0.271 0.302 -0.031 2.48e-06 0.274 0.299 -0.025 3.60e-07
BMI lassosum.MultiPRS LDpred2.MultiPRS 0.305 0.302 0.003 6.94e-01 0.305 0.299 0.006 2.85e-02
BMI PRScs.10FCVal LDpred2.MultiPRS 0.292 0.302 -0.010 1.23e-01 0.282 0.299 -0.018 1.17e-06
BMI PRScs.MultiPRS LDpred2.MultiPRS 0.301 0.302 -0.001 9.00e-01 0.296 0.299 -0.003 1.91e-01
BMI lassosum.PseudoVal LDpred2.MultiPRS 0.216 0.302 -0.086 8.31e-38 0.225 0.299 -0.074 2.02e-22
BMI LDpred2.PseudoVal LDpred2.MultiPRS 0.256 0.302 -0.046 5.51e-12 0.261 0.299 -0.038 2.79e-12
BMI LDpred1.MultiPRS LDpred2.MultiPRS 0.289 0.302 -0.013 4.22e-02 0.281 0.299 -0.018 6.82e-07
BMI LDpred2.MultiPRS LDpred2.MultiPRS 0.302 0.302 0.000 1.00e+00 0.299 0.299 0.000 1.00e+00
BMI LDpred1.Inf LDpred2.10FCVal 0.274 0.301 -0.027 3.02e-35 0.264 0.296 -0.032 8.61e-13
BMI PRScs.MultiPRS LDpred2.10FCVal 0.301 0.301 0.000 9.74e-01 0.296 0.296 0.000 9.90e-01
BMI LDpred2.MultiPRS LDpred2.10FCVal 0.302 0.301 0.001 9.26e-01 0.299 0.296 0.003 3.91e-03
BMI PRScs.PseudoVal LDpred2.10FCVal 0.282 0.301 -0.019 1.72e-19 0.282 0.296 -0.014 1.24e-03
BMI LDpred2.10FCVal LDpred2.10FCVal 0.301 0.301 0.000 1.00e+00 0.296 0.296 0.000 1.00e+00
BMI lassosum.MultiPRS LDpred2.10FCVal 0.305 0.301 0.003 6.27e-01 0.305 0.296 0.009 1.01e-03
BMI LDpred1.10FCVal LDpred2.10FCVal 0.279 0.301 -0.023 4.56e-27 0.271 0.296 -0.024 1.52e-08
BMI All.MultiPRS LDpred2.10FCVal 0.307 0.301 0.005 4.39e-01 0.305 0.296 0.009 2.20e-07
BMI SBayesR.PseudoVal LDpred2.10FCVal 0.211 0.301 -0.090 3.56e-115 0.224 0.296 -0.072 9.73e-20
BMI DBSLMM.PseudoVal LDpred2.10FCVal 0.285 0.301 -0.017 1.43e-17 0.283 0.296 -0.013 1.31e-03
BMI pT+clump.MultiPRS LDpred2.10FCVal 0.271 0.301 -0.030 4.44e-06 0.274 0.296 -0.022 1.30e-05
BMI lassosum.PseudoVal LDpred2.10FCVal 0.216 0.301 -0.086 9.23e-109 0.225 0.296 -0.071 1.69e-19
BMI PRScs.10FCVal LDpred2.10FCVal 0.292 0.301 -0.010 6.71e-09 0.282 0.296 -0.014 1.57e-05
BMI lassosum.10FCVal LDpred2.10FCVal 0.300 0.301 -0.001 4.36e-01 0.298 0.296 0.002 4.24e-01
BMI SBLUP.Inf LDpred2.10FCVal 0.293 0.301 -0.009 4.62e-10 0.286 0.296 -0.010 4.91e-04
BMI LDpred2.PseudoVal LDpred2.10FCVal 0.256 0.301 -0.045 1.55e-56 0.261 0.296 -0.035 2.65e-09
BMI pT+clump.10FCVal LDpred2.10FCVal 0.249 0.301 -0.053 5.90e-66 0.244 0.296 -0.052 8.97e-17
BMI LDpred2.Inf LDpred2.10FCVal 0.291 0.301 -0.010 1.96e-17 0.284 0.296 -0.012 3.34e-06
BMI LDpred1.MultiPRS LDpred2.10FCVal 0.289 0.301 -0.013 5.23e-02 0.281 0.296 -0.015 1.03e-04
BMI lassosum.10FCVal LDpred2.PseudoVal 0.300 0.256 0.044 4.85e-42 0.298 0.261 0.037 2.53e-08
BMI SBLUP.Inf LDpred2.PseudoVal 0.293 0.256 0.036 2.25e-21 0.286 0.261 0.025 1.56e-03
BMI SBayesR.PseudoVal LDpred2.PseudoVal 0.211 0.256 -0.045 3.19e-75 0.224 0.261 -0.037 1.36e-14
BMI All.MultiPRS LDpred2.PseudoVal 0.307 0.256 0.050 3.99e-14 0.305 0.261 0.044 2.93e-15
BMI PRScs.PseudoVal LDpred2.PseudoVal 0.282 0.256 0.026 8.05e-29 0.282 0.261 0.021 1.23e-05
BMI lassosum.MultiPRS LDpred2.PseudoVal 0.305 0.256 0.048 3.28e-13 0.305 0.261 0.044 1.18e-13
BMI PRScs.MultiPRS LDpred2.PseudoVal 0.301 0.256 0.045 1.33e-11 0.296 0.261 0.035 1.57e-08
BMI LDpred2.MultiPRS LDpred2.PseudoVal 0.302 0.256 0.046 5.51e-12 0.299 0.261 0.038 2.79e-12
BMI PRScs.10FCVal LDpred2.PseudoVal 0.292 0.256 0.036 1.82e-21 0.282 0.261 0.020 7.08e-03
BMI LDpred2.PseudoVal LDpred2.PseudoVal 0.256 0.256 0.000 1.00e+00 0.261 0.261 0.000 1.00e+00
BMI pT+clump.MultiPRS LDpred2.PseudoVal 0.271 0.256 0.015 2.85e-02 0.274 0.261 0.013 6.08e-02
BMI pT+clump.10FCVal LDpred2.PseudoVal 0.249 0.256 -0.008 7.13e-02 0.244 0.261 -0.017 4.56e-02
BMI lassosum.PseudoVal LDpred2.PseudoVal 0.216 0.256 -0.041 8.43e-81 0.225 0.261 -0.036 4.15e-17
BMI LDpred1.Inf LDpred2.PseudoVal 0.274 0.256 0.018 1.50e-06 0.264 0.261 0.003 7.32e-01
BMI LDpred1.MultiPRS LDpred2.PseudoVal 0.289 0.256 0.032 1.18e-06 0.281 0.261 0.020 3.79e-04
BMI LDpred1.10FCVal LDpred2.PseudoVal 0.279 0.256 0.022 9.05e-18 0.271 0.261 0.010 5.67e-02
BMI LDpred2.Inf LDpred2.PseudoVal 0.291 0.256 0.035 1.42e-20 0.284 0.261 0.023 2.47e-03
BMI LDpred2.10FCVal LDpred2.PseudoVal 0.301 0.256 0.045 1.55e-56 0.296 0.261 0.035 2.65e-09
BMI DBSLMM.PseudoVal LDpred2.PseudoVal 0.285 0.256 0.028 3.12e-26 0.283 0.261 0.022 5.11e-05
BMI pT+clump.MultiPRS LDpred2.Inf 0.271 0.291 -0.020 2.50e-03 0.274 0.284 -0.011 6.64e-02
BMI lassosum.MultiPRS LDpred2.Inf 0.305 0.291 0.014 3.98e-02 0.305 0.284 0.021 1.34e-08
BMI SBayesR.PseudoVal LDpred2.Inf 0.211 0.291 -0.080 2.75e-66 0.224 0.284 -0.060 9.04e-11
BMI All.MultiPRS LDpred2.Inf 0.307 0.291 0.015 1.90e-02 0.305 0.284 0.021 6.88e-12
BMI SBLUP.Inf LDpred2.Inf 0.293 0.291 0.001 3.68e-02 0.286 0.284 0.001 2.93e-01
BMI LDpred2.PseudoVal LDpred2.Inf 0.256 0.291 -0.035 1.42e-20 0.261 0.284 -0.023 2.47e-03
BMI PRScs.MultiPRS LDpred2.Inf 0.301 0.291 0.010 1.24e-01 0.296 0.284 0.011 3.14e-04
BMI LDpred2.MultiPRS LDpred2.Inf 0.302 0.291 0.011 9.56e-02 0.299 0.284 0.015 7.18e-08
BMI PRScs.10FCVal LDpred2.Inf 0.292 0.291 0.001 6.06e-01 0.282 0.284 -0.003 4.05e-01
BMI LDpred1.Inf LDpred2.Inf 0.274 0.291 -0.017 8.77e-18 0.264 0.284 -0.020 2.85e-07
BMI LDpred1.MultiPRS LDpred2.Inf 0.289 0.291 -0.002 7.13e-01 0.281 0.284 -0.003 4.59e-01
BMI pT+clump.10FCVal LDpred2.Inf 0.249 0.291 -0.042 2.32e-41 0.244 0.284 -0.040 2.47e-10
BMI lassosum.PseudoVal LDpred2.Inf 0.216 0.291 -0.075 4.85e-59 0.225 0.284 -0.059 3.09e-10
BMI PRScs.PseudoVal LDpred2.Inf 0.282 0.291 -0.009 1.40e-03 0.282 0.284 -0.002 6.72e-01
BMI DBSLMM.PseudoVal LDpred2.Inf 0.285 0.291 -0.007 9.40e-03 0.283 0.284 -0.001 8.05e-01
BMI LDpred1.10FCVal LDpred2.Inf 0.279 0.291 -0.013 2.67e-06 0.271 0.284 -0.013 1.73e-02
BMI LDpred2.Inf LDpred2.Inf 0.291 0.291 0.000 1.00e+00 0.284 0.284 0.000 1.00e+00
BMI lassosum.10FCVal LDpred2.Inf 0.300 0.291 0.009 2.07e-09 0.298 0.284 0.014 1.01e-05
BMI LDpred2.10FCVal LDpred2.Inf 0.301 0.291 0.010 1.96e-17 0.296 0.284 0.012 3.34e-06
BMI PRScs.10FCVal PRScs.MultiPRS 0.292 0.301 -0.009 1.57e-01 0.282 0.296 -0.014 3.55e-09
BMI LDpred1.10FCVal PRScs.MultiPRS 0.279 0.301 -0.023 5.93e-04 0.271 0.296 -0.024 3.94e-09
BMI lassosum.MultiPRS PRScs.MultiPRS 0.305 0.301 0.003 6.04e-01 0.305 0.296 0.009 3.02e-04
BMI LDpred2.MultiPRS PRScs.MultiPRS 0.302 0.301 0.001 9.00e-01 0.299 0.296 0.003 1.91e-01
BMI All.MultiPRS PRScs.MultiPRS 0.307 0.301 0.005 4.21e-01 0.305 0.296 0.009 2.83e-07
BMI PRScs.PseudoVal PRScs.MultiPRS 0.282 0.301 -0.019 4.09e-03 0.282 0.296 -0.014 5.30e-05
BMI LDpred1.MultiPRS PRScs.MultiPRS 0.289 0.301 -0.013 1.68e-11 0.281 0.296 -0.015 8.41e-05
BMI pT+clump.MultiPRS PRScs.MultiPRS 0.271 0.301 -0.030 5.21e-06 0.274 0.296 -0.022 6.32e-06
BMI lassosum.PseudoVal PRScs.MultiPRS 0.216 0.301 -0.085 1.97e-37 0.225 0.296 -0.071 1.32e-20
BMI SBayesR.PseudoVal PRScs.MultiPRS 0.211 0.301 -0.090 6.17e-41 0.224 0.296 -0.072 6.39e-20
BMI DBSLMM.PseudoVal PRScs.MultiPRS 0.285 0.301 -0.017 1.16e-02 0.283 0.296 -0.013 5.21e-04
BMI SBLUP.Inf PRScs.MultiPRS 0.293 0.301 -0.009 1.85e-01 0.286 0.296 -0.010 7.74e-04
BMI LDpred2.Inf PRScs.MultiPRS 0.291 0.301 -0.010 1.24e-01 0.284 0.296 -0.011 3.14e-04
BMI pT+clump.10FCVal PRScs.MultiPRS 0.249 0.301 -0.053 2.78e-15 0.244 0.296 -0.052 6.57e-17
BMI LDpred2.10FCVal PRScs.MultiPRS 0.301 0.301 0.000 9.74e-01 0.296 0.296 0.000 9.90e-01
BMI lassosum.10FCVal PRScs.MultiPRS 0.300 0.301 -0.001 8.93e-01 0.298 0.296 0.002 3.71e-01
BMI LDpred2.PseudoVal PRScs.MultiPRS 0.256 0.301 -0.045 1.33e-11 0.261 0.296 -0.035 1.57e-08
BMI LDpred1.Inf PRScs.MultiPRS 0.274 0.301 -0.027 4.87e-05 0.264 0.296 -0.032 3.29e-13
BMI PRScs.MultiPRS PRScs.MultiPRS 0.301 0.301 0.000 1.00e+00 0.296 0.296 0.000 1.00e+00
BMI LDpred2.PseudoVal PRScs.10FCVal 0.256 0.292 -0.036 1.82e-21 0.261 0.282 -0.020 7.08e-03
BMI PRScs.10FCVal PRScs.10FCVal 0.292 0.292 0.000 1.00e+00 0.282 0.282 0.000 1.00e+00
BMI LDpred2.MultiPRS PRScs.10FCVal 0.302 0.292 0.010 1.23e-01 0.299 0.282 0.018 1.17e-06
BMI pT+clump.MultiPRS PRScs.10FCVal 0.271 0.292 -0.021 1.66e-03 0.274 0.282 -0.008 1.42e-01
BMI LDpred1.Inf PRScs.10FCVal 0.274 0.292 -0.018 8.76e-13 0.264 0.282 -0.018 3.37e-04
BMI LDpred1.MultiPRS PRScs.10FCVal 0.289 0.292 -0.003 6.23e-01 0.281 0.282 -0.001 8.88e-01
BMI pT+clump.10FCVal PRScs.10FCVal 0.249 0.292 -0.043 1.42e-45 0.244 0.282 -0.038 8.95e-10
BMI lassosum.PseudoVal PRScs.10FCVal 0.216 0.292 -0.076 2.00e-64 0.225 0.282 -0.057 3.90e-10
BMI PRScs.PseudoVal PRScs.10FCVal 0.282 0.292 -0.010 4.62e-04 0.282 0.282 0.000 9.59e-01
BMI DBSLMM.PseudoVal PRScs.10FCVal 0.285 0.292 -0.007 2.41e-03 0.283 0.282 0.001 7.74e-01
BMI SBLUP.Inf PRScs.10FCVal 0.293 0.292 0.001 6.72e-01 0.286 0.282 0.004 1.48e-01
BMI LDpred2.Inf PRScs.10FCVal 0.291 0.292 -0.001 6.06e-01 0.284 0.282 0.003 4.05e-01
BMI lassosum.10FCVal PRScs.10FCVal 0.300 0.292 0.008 1.71e-07 0.298 0.282 0.016 3.45e-07
BMI LDpred2.10FCVal PRScs.10FCVal 0.301 0.292 0.010 6.71e-09 0.296 0.282 0.014 1.57e-05
BMI lassosum.MultiPRS PRScs.10FCVal 0.305 0.292 0.013 5.32e-02 0.305 0.282 0.023 8.25e-12
BMI LDpred1.10FCVal PRScs.10FCVal 0.279 0.292 -0.013 1.50e-06 0.271 0.282 -0.010 6.51e-02
BMI All.MultiPRS PRScs.10FCVal 0.307 0.292 0.015 2.62e-02 0.305 0.282 0.024 2.66e-15
BMI SBayesR.PseudoVal PRScs.10FCVal 0.211 0.292 -0.080 5.46e-70 0.224 0.282 -0.058 2.74e-10
BMI PRScs.MultiPRS PRScs.10FCVal 0.301 0.292 0.009 1.57e-01 0.296 0.282 0.014 3.55e-09
BMI All.MultiPRS PRScs.PseudoVal 0.307 0.282 0.024 2.41e-04 0.305 0.282 0.023 2.68e-09
BMI pT+clump.MultiPRS PRScs.PseudoVal 0.271 0.282 -0.011 9.08e-02 0.274 0.282 -0.008 1.56e-01
BMI LDpred2.PseudoVal PRScs.PseudoVal 0.256 0.282 -0.026 8.05e-29 0.261 0.282 -0.021 1.23e-05
BMI SBayesR.PseudoVal PRScs.PseudoVal 0.211 0.282 -0.071 2.10e-112 0.224 0.282 -0.058 2.44e-20
BMI LDpred2.MultiPRS PRScs.PseudoVal 0.302 0.282 0.020 2.74e-03 0.299 0.282 0.017 3.98e-05
BMI SBLUP.Inf PRScs.PseudoVal 0.293 0.282 0.010 2.20e-04 0.286 0.282 0.004 4.96e-01
BMI LDpred1.Inf PRScs.PseudoVal 0.274 0.282 -0.008 3.92e-03 0.264 0.282 -0.018 1.33e-03
BMI PRScs.10FCVal PRScs.PseudoVal 0.292 0.282 0.010 4.62e-04 0.282 0.282 0.000 9.59e-01
BMI LDpred2.Inf PRScs.PseudoVal 0.291 0.282 0.009 1.40e-03 0.284 0.282 0.002 6.72e-01
BMI PRScs.PseudoVal PRScs.PseudoVal 0.282 0.282 0.000 1.00e+00 0.282 0.282 0.000 1.00e+00
BMI LDpred2.10FCVal PRScs.PseudoVal 0.301 0.282 0.019 1.72e-19 0.296 0.282 0.014 1.24e-03
BMI pT+clump.10FCVal PRScs.PseudoVal 0.249 0.282 -0.034 9.68e-20 0.244 0.282 -0.038 4.85e-07
BMI PRScs.MultiPRS PRScs.PseudoVal 0.301 0.282 0.019 4.09e-03 0.296 0.282 0.014 5.30e-05
BMI lassosum.PseudoVal PRScs.PseudoVal 0.216 0.282 -0.067 9.48e-133 0.225 0.282 -0.057 3.33e-25
BMI lassosum.10FCVal PRScs.PseudoVal 0.300 0.282 0.018 2.39e-15 0.298 0.282 0.016 4.95e-04
BMI LDpred1.MultiPRS PRScs.PseudoVal 0.289 0.282 0.006 3.36e-01 0.281 0.282 -0.001 8.11e-01
BMI lassosum.MultiPRS PRScs.PseudoVal 0.305 0.282 0.022 7.11e-04 0.305 0.282 0.023 1.08e-07
BMI LDpred1.10FCVal PRScs.PseudoVal 0.279 0.282 -0.004 3.05e-02 0.271 0.282 -0.011 2.85e-03
BMI DBSLMM.PseudoVal PRScs.PseudoVal 0.285 0.282 0.002 1.91e-01 0.283 0.282 0.001 7.51e-01
BMI All.MultiPRS pT+clump.MultiPRS 0.307 0.271 0.036 7.60e-08 0.305 0.274 0.031 2.37e-12
BMI SBayesR.PseudoVal pT+clump.MultiPRS 0.211 0.271 -0.060 1.50e-18 0.224 0.274 -0.050 9.43e-10
BMI LDpred1.MultiPRS pT+clump.MultiPRS 0.289 0.271 0.018 8.03e-03 0.281 0.274 0.007 2.00e-01
BMI pT+clump.MultiPRS pT+clump.MultiPRS 0.271 0.271 0.000 1.00e+00 0.274 0.274 0.000 1.00e+00
BMI lassosum.PseudoVal pT+clump.MultiPRS 0.216 0.271 -0.055 3.91e-16 0.225 0.274 -0.049 3.37e-10
BMI PRScs.10FCVal pT+clump.MultiPRS 0.292 0.271 0.021 1.66e-03 0.282 0.274 0.008 1.42e-01
BMI DBSLMM.PseudoVal pT+clump.MultiPRS 0.285 0.271 0.014 4.17e-02 0.283 0.274 0.009 9.36e-02
BMI SBLUP.Inf pT+clump.MultiPRS 0.293 0.271 0.021 1.20e-03 0.286 0.274 0.012 3.00e-02
BMI LDpred2.Inf pT+clump.MultiPRS 0.291 0.271 0.020 2.50e-03 0.284 0.274 0.011 6.64e-02
BMI pT+clump.10FCVal pT+clump.MultiPRS 0.249 0.271 -0.022 8.45e-04 0.244 0.274 -0.030 8.69e-14
BMI LDpred2.10FCVal pT+clump.MultiPRS 0.301 0.271 0.030 4.44e-06 0.296 0.274 0.022 1.30e-05
BMI PRScs.PseudoVal pT+clump.MultiPRS 0.282 0.271 0.011 9.08e-02 0.282 0.274 0.008 1.56e-01
BMI LDpred1.10FCVal pT+clump.MultiPRS 0.279 0.271 0.008 2.60e-01 0.271 0.274 -0.002 6.78e-01
BMI LDpred1.Inf pT+clump.MultiPRS 0.274 0.271 0.003 6.17e-01 0.264 0.274 -0.010 1.15e-01
BMI PRScs.MultiPRS pT+clump.MultiPRS 0.301 0.271 0.030 5.21e-06 0.296 0.274 0.022 6.32e-06
BMI lassosum.10FCVal pT+clump.MultiPRS 0.300 0.271 0.029 9.78e-06 0.298 0.274 0.024 1.37e-06
BMI LDpred2.PseudoVal pT+clump.MultiPRS 0.256 0.271 -0.015 2.85e-02 0.261 0.274 -0.013 6.08e-02
BMI lassosum.MultiPRS pT+clump.MultiPRS 0.305 0.271 0.034 3.77e-07 0.305 0.274 0.031 4.02e-11
BMI LDpred2.MultiPRS pT+clump.MultiPRS 0.302 0.271 0.031 2.48e-06 0.299 0.274 0.025 3.60e-07
BMI LDpred2.10FCVal pT+clump.10FCVal 0.301 0.249 0.053 5.90e-66 0.296 0.244 0.052 8.97e-17
BMI pT+clump.MultiPRS pT+clump.10FCVal 0.271 0.249 0.022 8.45e-04 0.274 0.244 0.030 8.69e-14
BMI LDpred2.Inf pT+clump.10FCVal 0.291 0.249 0.042 2.32e-41 0.284 0.244 0.040 2.47e-10
BMI SBayesR.PseudoVal pT+clump.10FCVal 0.211 0.249 -0.037 4.18e-14 0.224 0.244 -0.020 4.33e-02
BMI PRScs.MultiPRS pT+clump.10FCVal 0.301 0.249 0.053 2.78e-15 0.296 0.244 0.052 6.57e-17
BMI SBLUP.Inf pT+clump.10FCVal 0.293 0.249 0.044 5.05e-47 0.286 0.244 0.042 1.09e-11
BMI lassosum.MultiPRS pT+clump.10FCVal 0.305 0.249 0.056 4.19e-17 0.305 0.244 0.061 6.01e-25
BMI PRScs.10FCVal pT+clump.10FCVal 0.292 0.249 0.043 1.42e-45 0.282 0.244 0.038 8.95e-10
BMI LDpred2.MultiPRS pT+clump.10FCVal 0.302 0.249 0.053 9.71e-16 0.299 0.244 0.055 9.79e-19
BMI lassosum.10FCVal pT+clump.10FCVal 0.300 0.249 0.052 6.29e-69 0.298 0.244 0.054 6.65e-20
BMI LDpred2.PseudoVal pT+clump.10FCVal 0.256 0.249 0.008 7.13e-02 0.261 0.244 0.017 4.56e-02
BMI LDpred1.MultiPRS pT+clump.10FCVal 0.289 0.249 0.040 2.05e-09 0.281 0.244 0.037 1.49e-07
BMI pT+clump.10FCVal pT+clump.10FCVal 0.249 0.249 0.000 1.00e+00 0.244 0.244 0.000 1.00e+00
BMI All.MultiPRS pT+clump.10FCVal 0.307 0.249 0.058 2.54e-18 0.305 0.244 0.061 2.24e-26
BMI LDpred1.Inf pT+clump.10FCVal 0.274 0.249 0.026 2.12e-13 0.264 0.244 0.020 5.30e-03
BMI DBSLMM.PseudoVal pT+clump.10FCVal 0.285 0.249 0.036 9.11e-24 0.283 0.244 0.039 1.02e-07
BMI LDpred1.10FCVal pT+clump.10FCVal 0.279 0.249 0.030 5.32e-16 0.271 0.244 0.027 2.79e-04
BMI lassosum.PseudoVal pT+clump.10FCVal 0.216 0.249 -0.033 1.27e-11 0.225 0.244 -0.019 5.37e-02
BMI PRScs.PseudoVal pT+clump.10FCVal 0.282 0.249 0.034 9.68e-20 0.282 0.244 0.038 4.85e-07
BMI pT+clump.MultiPRS SBayesR.PseudoVal 0.271 0.211 0.060 1.50e-18 0.274 0.224 0.050 9.43e-10
BMI LDpred1.10FCVal SBayesR.PseudoVal 0.279 0.211 0.067 4.00e-81 0.271 0.224 0.047 2.08e-11
BMI PRScs.10FCVal SBayesR.PseudoVal 0.292 0.211 0.080 5.46e-70 0.282 0.224 0.058 2.74e-10
BMI LDpred2.10FCVal SBayesR.PseudoVal 0.301 0.211 0.090 3.56e-115 0.296 0.224 0.072 9.73e-20
BMI lassosum.10FCVal SBayesR.PseudoVal 0.300 0.211 0.089 9.78e-100 0.298 0.224 0.074 1.52e-18
BMI LDpred2.PseudoVal SBayesR.PseudoVal 0.256 0.211 0.045 3.19e-75 0.261 0.224 0.037 1.36e-14
BMI lassosum.MultiPRS SBayesR.PseudoVal 0.305 0.211 0.093 5.75e-44 0.305 0.224 0.081 1.44e-25
BMI LDpred2.MultiPRS SBayesR.PseudoVal 0.302 0.211 0.091 9.68e-42 0.299 0.224 0.075 6.96e-23
BMI All.MultiPRS SBayesR.PseudoVal 0.307 0.211 0.095 1.34e-45 0.305 0.224 0.081 7.00e-27
BMI PRScs.PseudoVal SBayesR.PseudoVal 0.282 0.211 0.071 2.10e-112 0.282 0.224 0.058 2.44e-20
BMI LDpred1.MultiPRS SBayesR.PseudoVal 0.289 0.211 0.077 1.36e-30 0.281 0.224 0.057 8.42e-15
BMI pT+clump.10FCVal SBayesR.PseudoVal 0.249 0.211 0.037 4.18e-14 0.244 0.224 0.020 4.33e-02
BMI lassosum.PseudoVal SBayesR.PseudoVal 0.216 0.211 0.004 1.10e-01 0.225 0.224 0.001 8.44e-01
BMI SBayesR.PseudoVal SBayesR.PseudoVal 0.211 0.211 0.000 1.00e+00 0.224 0.224 0.000 1.00e+00
BMI DBSLMM.PseudoVal SBayesR.PseudoVal 0.285 0.211 0.073 6.58e-118 0.283 0.224 0.059 7.93e-21
BMI SBLUP.Inf SBayesR.PseudoVal 0.293 0.211 0.081 7.27e-68 0.286 0.224 0.062 3.83e-11
BMI LDpred2.Inf SBayesR.PseudoVal 0.291 0.211 0.080 2.75e-66 0.284 0.224 0.060 9.04e-11
BMI LDpred1.Inf SBayesR.PseudoVal 0.274 0.211 0.063 3.89e-43 0.264 0.224 0.040 1.51e-05
BMI PRScs.MultiPRS SBayesR.PseudoVal 0.301 0.211 0.090 6.17e-41 0.296 0.224 0.072 6.39e-20
BMI LDpred2.10FCVal SBLUP.Inf 0.301 0.293 0.009 4.62e-10 0.296 0.286 0.010 4.91e-04
BMI PRScs.PseudoVal SBLUP.Inf 0.282 0.293 -0.010 2.20e-04 0.282 0.286 -0.004 4.96e-01
BMI LDpred1.10FCVal SBLUP.Inf 0.279 0.293 -0.014 1.93e-07 0.271 0.286 -0.014 8.23e-03
BMI LDpred2.Inf SBLUP.Inf 0.291 0.293 -0.001 3.68e-02 0.284 0.286 -0.001 2.93e-01
BMI SBayesR.PseudoVal SBLUP.Inf 0.211 0.293 -0.081 7.27e-68 0.224 0.286 -0.062 3.83e-11
BMI lassosum.10FCVal SBLUP.Inf 0.300 0.293 0.008 1.15e-07 0.298 0.286 0.012 3.01e-05
BMI pT+clump.MultiPRS SBLUP.Inf 0.271 0.293 -0.021 1.20e-03 0.274 0.286 -0.012 3.00e-02
BMI lassosum.MultiPRS SBLUP.Inf 0.305 0.293 0.012 6.56e-02 0.305 0.286 0.019 2.91e-08
BMI PRScs.10FCVal SBLUP.Inf 0.292 0.293 -0.001 6.72e-01 0.282 0.286 -0.004 1.48e-01
BMI PRScs.MultiPRS SBLUP.Inf 0.301 0.293 0.009 1.85e-01 0.296 0.286 0.010 7.74e-04
BMI LDpred1.MultiPRS SBLUP.Inf 0.289 0.293 -0.004 5.61e-01 0.281 0.286 -0.005 2.89e-01
BMI LDpred2.PseudoVal SBLUP.Inf 0.256 0.293 -0.036 2.25e-21 0.261 0.286 -0.025 1.56e-03
BMI LDpred1.Inf SBLUP.Inf 0.274 0.293 -0.018 6.95e-21 0.264 0.286 -0.022 3.52e-08
BMI LDpred2.MultiPRS SBLUP.Inf 0.302 0.293 0.010 1.47e-01 0.299 0.286 0.013 1.63e-05
BMI All.MultiPRS SBLUP.Inf 0.307 0.293 0.014 3.30e-02 0.305 0.286 0.019 4.50e-11
BMI SBLUP.Inf SBLUP.Inf 0.293 0.293 0.000 1.00e+00 0.286 0.286 0.000 1.00e+00
BMI DBSLMM.PseudoVal SBLUP.Inf 0.285 0.293 -0.008 1.44e-03 0.283 0.286 -0.003 5.94e-01
BMI pT+clump.10FCVal SBLUP.Inf 0.249 0.293 -0.044 5.05e-47 0.244 0.286 -0.042 1.09e-11
BMI lassosum.PseudoVal SBLUP.Inf 0.216 0.293 -0.077 1.34e-60 0.225 0.286 -0.061 1.28e-10
T2D LDpred2.PseudoVal All.MultiPRS 0.194 0.242 -0.048 1.79e-12 0.190 0.242 -0.052 6.78e-17
T2D pT+clump.10FCVal All.MultiPRS 0.167 0.242 -0.075 7.70e-28 0.173 0.242 -0.069 5.83e-19
T2D LDpred2.MultiPRS All.MultiPRS 0.242 0.242 0.000 9.96e-01 0.240 0.242 -0.002 2.13e-01
T2D PRScs.PseudoVal All.MultiPRS 0.226 0.242 -0.015 2.34e-02 0.226 0.242 -0.016 4.31e-05
T2D LDpred1.Inf All.MultiPRS 0.187 0.242 -0.055 9.62e-16 0.184 0.242 -0.057 4.48e-18
T2D PRScs.MultiPRS All.MultiPRS 0.235 0.242 -0.007 2.83e-01 0.237 0.242 -0.005 1.15e-01
T2D LDpred2.Inf All.MultiPRS 0.189 0.242 -0.053 1.10e-14 0.185 0.242 -0.057 3.30e-18
T2D lassosum.10FCVal All.MultiPRS 0.214 0.242 -0.028 3.25e-05 0.216 0.242 -0.026 1.79e-07
T2D LDpred2.10FCVal All.MultiPRS 0.237 0.242 -0.005 4.46e-01 0.238 0.242 -0.004 1.45e-01
T2D lassosum.MultiPRS All.MultiPRS 0.237 0.242 -0.004 5.05e-01 0.240 0.242 -0.001 5.62e-01
T2D LDpred1.10FCVal All.MultiPRS 0.232 0.242 -0.010 1.43e-01 0.230 0.242 -0.012 5.10e-04
T2D All.MultiPRS All.MultiPRS 0.242 0.242 0.000 1.00e+00 0.242 0.242 0.000 1.00e+00
T2D SBayesR.PseudoVal All.MultiPRS 0.226 0.242 -0.016 2.17e-02 0.227 0.242 -0.014 2.02e-04
T2D LDpred1.MultiPRS All.MultiPRS 0.232 0.242 -0.010 5.11e-09 0.231 0.242 -0.011 8.86e-04
T2D pT+clump.MultiPRS All.MultiPRS 0.212 0.242 -0.030 8.65e-06 0.215 0.242 -0.027 1.25e-07
T2D lassosum.PseudoVal All.MultiPRS 0.206 0.242 -0.036 9.54e-08 0.214 0.242 -0.027 8.48e-07
T2D PRScs.10FCVal All.MultiPRS 0.228 0.242 -0.014 3.88e-02 0.227 0.242 -0.015 1.01e-04
T2D DBSLMM.PseudoVal All.MultiPRS 0.229 0.242 -0.013 6.19e-02 0.226 0.242 -0.015 1.77e-05
T2D SBLUP.Inf All.MultiPRS 0.189 0.242 -0.053 1.08e-14 0.184 0.242 -0.057 1.24e-18
T2D SBayesR.PseudoVal DBSLMM.PseudoVal 0.226 0.229 -0.003 2.83e-01 0.227 0.226 0.001 8.61e-01
T2D LDpred2.Inf DBSLMM.PseudoVal 0.189 0.229 -0.040 1.66e-45 0.185 0.226 -0.041 2.09e-13
T2D pT+clump.10FCVal DBSLMM.PseudoVal 0.167 0.229 -0.062 1.53e-47 0.173 0.226 -0.054 2.59e-10
T2D PRScs.10FCVal DBSLMM.PseudoVal 0.228 0.229 -0.001 5.03e-01 0.227 0.226 0.001 8.31e-01
T2D PRScs.PseudoVal DBSLMM.PseudoVal 0.226 0.229 -0.003 1.75e-01 0.226 0.226 0.000 9.03e-01
T2D pT+clump.MultiPRS DBSLMM.PseudoVal 0.212 0.229 -0.018 1.01e-02 0.215 0.226 -0.011 2.49e-02
T2D LDpred1.Inf DBSLMM.PseudoVal 0.187 0.229 -0.042 4.35e-48 0.184 0.226 -0.042 2.33e-13
T2D lassosum.MultiPRS DBSLMM.PseudoVal 0.237 0.229 0.008 2.28e-01 0.240 0.226 0.014 1.14e-04
T2D LDpred2.10FCVal DBSLMM.PseudoVal 0.237 0.229 0.008 8.86e-05 0.238 0.226 0.011 2.47e-03
T2D lassosum.10FCVal DBSLMM.PseudoVal 0.214 0.229 -0.016 1.77e-07 0.216 0.226 -0.011 6.96e-02
T2D LDpred1.10FCVal DBSLMM.PseudoVal 0.232 0.229 0.003 1.96e-01 0.230 0.226 0.004 3.65e-01
T2D LDpred1.MultiPRS DBSLMM.PseudoVal 0.232 0.229 0.003 6.74e-01 0.231 0.226 0.005 2.77e-01
T2D PRScs.MultiPRS DBSLMM.PseudoVal 0.235 0.229 0.005 4.27e-01 0.237 0.226 0.011 2.46e-03
T2D All.MultiPRS DBSLMM.PseudoVal 0.242 0.229 0.013 6.19e-02 0.242 0.226 0.015 1.77e-05
T2D LDpred2.PseudoVal DBSLMM.PseudoVal 0.194 0.229 -0.035 2.16e-38 0.190 0.226 -0.037 1.28e-11
T2D DBSLMM.PseudoVal DBSLMM.PseudoVal 0.229 0.229 0.000 1.00e+00 0.226 0.226 0.000 1.00e+00
T2D LDpred2.MultiPRS DBSLMM.PseudoVal 0.242 0.229 0.013 6.08e-02 0.240 0.226 0.014 2.71e-04
T2D lassosum.PseudoVal DBSLMM.PseudoVal 0.206 0.229 -0.024 1.17e-10 0.214 0.226 -0.012 9.36e-02
T2D SBLUP.Inf DBSLMM.PseudoVal 0.189 0.229 -0.040 4.70e-46 0.184 0.226 -0.042 4.78e-14
T2D SBayesR.PseudoVal lassosum.MultiPRS 0.226 0.237 -0.011 1.02e-01 0.227 0.240 -0.013 1.37e-03
T2D LDpred2.10FCVal lassosum.MultiPRS 0.237 0.237 -0.001 9.22e-01 0.238 0.240 -0.003 2.78e-01
T2D LDpred1.10FCVal lassosum.MultiPRS 0.232 0.237 -0.005 4.23e-01 0.230 0.240 -0.010 5.87e-04
T2D LDpred2.Inf lassosum.MultiPRS 0.189 0.237 -0.048 1.60e-12 0.185 0.240 -0.055 6.80e-18
T2D PRScs.10FCVal lassosum.MultiPRS 0.228 0.237 -0.010 1.61e-01 0.227 0.240 -0.013 2.89e-04
T2D PRScs.MultiPRS lassosum.MultiPRS 0.235 0.237 -0.003 6.81e-01 0.237 0.240 -0.003 2.05e-01
T2D pT+clump.MultiPRS lassosum.MultiPRS 0.212 0.237 -0.026 1.46e-04 0.215 0.240 -0.025 5.80e-08
T2D lassosum.MultiPRS lassosum.MultiPRS 0.237 0.237 0.000 1.00e+00 0.240 0.240 0.000 1.00e+00
T2D lassosum.PseudoVal lassosum.MultiPRS 0.206 0.237 -0.032 3.12e-06 0.214 0.240 -0.026 1.36e-07
T2D LDpred2.MultiPRS lassosum.MultiPRS 0.242 0.237 0.005 5.03e-01 0.240 0.240 0.000 9.04e-01
T2D LDpred1.MultiPRS lassosum.MultiPRS 0.232 0.237 -0.005 4.32e-01 0.231 0.240 -0.009 1.01e-03
T2D LDpred2.PseudoVal lassosum.MultiPRS 0.194 0.237 -0.044 1.67e-10 0.190 0.240 -0.051 7.52e-17
T2D LDpred1.Inf lassosum.MultiPRS 0.187 0.237 -0.050 1.74e-13 0.184 0.240 -0.056 2.15e-18
T2D pT+clump.10FCVal lassosum.MultiPRS 0.167 0.237 -0.071 5.84e-25 0.173 0.240 -0.068 6.94e-20
T2D lassosum.10FCVal lassosum.MultiPRS 0.214 0.237 -0.024 4.82e-04 0.216 0.240 -0.025 4.04e-09
T2D SBLUP.Inf lassosum.MultiPRS 0.189 0.237 -0.048 1.59e-12 0.184 0.240 -0.056 1.38e-18
T2D DBSLMM.PseudoVal lassosum.MultiPRS 0.229 0.237 -0.008 2.28e-01 0.226 0.240 -0.014 1.14e-04
T2D All.MultiPRS lassosum.MultiPRS 0.242 0.237 0.004 5.05e-01 0.242 0.240 0.001 5.62e-01
T2D PRScs.PseudoVal lassosum.MultiPRS 0.226 0.237 -0.011 1.09e-01 0.226 0.240 -0.014 7.36e-05
T2D LDpred1.Inf lassosum.PseudoVal 0.187 0.206 -0.019 2.56e-04 0.184 0.214 -0.030 2.87e-03
T2D PRScs.10FCVal lassosum.PseudoVal 0.228 0.206 0.022 2.96e-10 0.227 0.214 0.013 6.75e-02
T2D LDpred2.MultiPRS lassosum.PseudoVal 0.242 0.206 0.036 9.62e-08 0.240 0.214 0.026 7.12e-06
T2D lassosum.PseudoVal lassosum.PseudoVal 0.206 0.206 0.000 1.00e+00 0.214 0.214 0.000 1.00e+00
T2D PRScs.PseudoVal lassosum.PseudoVal 0.226 0.206 0.021 5.80e-09 0.226 0.214 0.012 1.03e-01
T2D DBSLMM.PseudoVal lassosum.PseudoVal 0.229 0.206 0.024 1.17e-10 0.226 0.214 0.012 9.36e-02
T2D SBLUP.Inf lassosum.PseudoVal 0.189 0.206 -0.017 1.30e-03 0.184 0.214 -0.030 3.09e-03
T2D LDpred2.Inf lassosum.PseudoVal 0.189 0.206 -0.017 1.33e-03 0.185 0.214 -0.029 4.15e-03
T2D pT+clump.10FCVal lassosum.PseudoVal 0.167 0.206 -0.039 3.94e-34 0.173 0.214 -0.042 4.23e-11
T2D LDpred2.10FCVal lassosum.PseudoVal 0.237 0.206 0.031 1.68e-30 0.238 0.214 0.023 1.38e-05
T2D lassosum.MultiPRS lassosum.PseudoVal 0.237 0.206 0.032 3.12e-06 0.240 0.214 0.026 1.36e-07
T2D LDpred1.10FCVal lassosum.PseudoVal 0.232 0.206 0.026 1.05e-19 0.230 0.214 0.016 5.85e-03
T2D All.MultiPRS lassosum.PseudoVal 0.242 0.206 0.036 9.54e-08 0.242 0.214 0.027 8.48e-07
T2D SBayesR.PseudoVal lassosum.PseudoVal 0.226 0.206 0.021 1.83e-18 0.227 0.214 0.013 5.67e-03
T2D lassosum.10FCVal lassosum.PseudoVal 0.214 0.206 0.008 6.43e-03 0.216 0.214 0.001 8.10e-01
T2D pT+clump.MultiPRS lassosum.PseudoVal 0.212 0.206 0.006 3.79e-01 0.215 0.214 0.001 9.15e-01
T2D LDpred2.PseudoVal lassosum.PseudoVal 0.194 0.206 -0.012 1.71e-02 0.190 0.214 -0.025 1.22e-02
T2D LDpred1.MultiPRS lassosum.PseudoVal 0.232 0.206 0.026 1.04e-04 0.231 0.214 0.017 2.81e-03
T2D PRScs.MultiPRS lassosum.PseudoVal 0.235 0.206 0.029 2.30e-05 0.237 0.214 0.023 9.22e-05
T2D lassosum.10FCVal lassosum.10FCVal 0.214 0.214 0.000 1.00e+00 0.216 0.216 0.000 1.00e+00
T2D pT+clump.MultiPRS lassosum.10FCVal 0.212 0.214 -0.002 7.70e-01 0.215 0.216 -0.001 9.07e-01
T2D LDpred2.Inf lassosum.10FCVal 0.189 0.214 -0.025 4.13e-13 0.185 0.216 -0.031 4.35e-06
T2D SBayesR.PseudoVal lassosum.10FCVal 0.226 0.214 0.013 1.35e-05 0.227 0.216 0.012 4.36e-02
T2D PRScs.MultiPRS lassosum.10FCVal 0.235 0.214 0.021 2.13e-03 0.237 0.216 0.021 1.55e-06
T2D SBLUP.Inf lassosum.10FCVal 0.189 0.214 -0.025 3.02e-13 0.184 0.216 -0.031 1.96e-06
T2D lassosum.MultiPRS lassosum.10FCVal 0.237 0.214 0.024 4.82e-04 0.240 0.216 0.025 4.04e-09
T2D PRScs.10FCVal lassosum.10FCVal 0.228 0.214 0.014 7.41e-10 0.227 0.216 0.012 1.22e-02
T2D LDpred2.MultiPRS lassosum.10FCVal 0.242 0.214 0.028 3.19e-05 0.240 0.216 0.024 1.59e-06
T2D PRScs.PseudoVal lassosum.10FCVal 0.226 0.214 0.013 4.14e-08 0.226 0.216 0.010 2.86e-02
T2D LDpred2.PseudoVal lassosum.10FCVal 0.194 0.214 -0.020 8.22e-10 0.190 0.216 -0.026 4.30e-05
T2D LDpred1.MultiPRS lassosum.10FCVal 0.232 0.214 0.018 6.86e-03 0.231 0.216 0.015 5.02e-05
T2D pT+clump.10FCVal lassosum.10FCVal 0.167 0.214 -0.047 2.14e-26 0.173 0.216 -0.043 8.50e-07
T2D All.MultiPRS lassosum.10FCVal 0.242 0.214 0.028 3.25e-05 0.242 0.216 0.026 1.79e-07
T2D LDpred1.Inf lassosum.10FCVal 0.187 0.214 -0.027 3.27e-15 0.184 0.216 -0.031 2.25e-06
T2D DBSLMM.PseudoVal lassosum.10FCVal 0.229 0.214 0.016 1.77e-07 0.226 0.216 0.011 6.96e-02
T2D LDpred1.10FCVal lassosum.10FCVal 0.232 0.214 0.018 3.68e-22 0.230 0.216 0.014 1.07e-04
T2D lassosum.PseudoVal lassosum.10FCVal 0.206 0.214 -0.008 6.43e-03 0.214 0.216 -0.001 8.10e-01
T2D LDpred2.10FCVal lassosum.10FCVal 0.237 0.214 0.023 1.36e-34 0.238 0.216 0.022 4.27e-09
T2D LDpred2.10FCVal LDpred1.MultiPRS 0.237 0.232 0.005 4.93e-01 0.238 0.231 0.007 8.48e-04
T2D PRScs.PseudoVal LDpred1.MultiPRS 0.226 0.232 -0.006 4.13e-01 0.226 0.231 -0.005 1.29e-01
T2D LDpred2.Inf LDpred1.MultiPRS 0.189 0.232 -0.043 3.59e-10 0.185 0.231 -0.046 2.78e-14
T2D pT+clump.10FCVal LDpred1.MultiPRS 0.167 0.232 -0.065 2.36e-21 0.173 0.231 -0.058 3.83e-13
T2D SBayesR.PseudoVal LDpred1.MultiPRS 0.226 0.232 -0.006 3.96e-01 0.227 0.231 -0.004 4.27e-01
T2D All.MultiPRS LDpred1.MultiPRS 0.242 0.232 0.010 5.11e-09 0.242 0.231 0.011 8.86e-04
T2D LDpred1.10FCVal LDpred1.MultiPRS 0.232 0.232 0.000 9.86e-01 0.230 0.231 -0.001 8.06e-02
T2D LDpred1.MultiPRS LDpred1.MultiPRS 0.232 0.232 0.000 1.00e+00 0.231 0.231 0.000 1.00e+00
T2D PRScs.10FCVal LDpred1.MultiPRS 0.228 0.232 -0.004 5.37e-01 0.227 0.231 -0.004 2.60e-01
T2D lassosum.PseudoVal LDpred1.MultiPRS 0.206 0.232 -0.026 1.04e-04 0.214 0.231 -0.017 2.81e-03
T2D pT+clump.MultiPRS LDpred1.MultiPRS 0.212 0.232 -0.020 2.67e-03 0.215 0.231 -0.016 1.96e-03
T2D LDpred1.Inf LDpred1.MultiPRS 0.187 0.232 -0.045 4.85e-11 0.184 0.231 -0.047 3.90e-16
T2D lassosum.MultiPRS LDpred1.MultiPRS 0.237 0.232 0.005 4.32e-01 0.240 0.231 0.009 1.01e-03
T2D PRScs.MultiPRS LDpred1.MultiPRS 0.235 0.232 0.003 7.10e-01 0.237 0.231 0.006 2.13e-02
T2D lassosum.10FCVal LDpred1.MultiPRS 0.214 0.232 -0.018 6.86e-03 0.216 0.231 -0.015 5.02e-05
T2D LDpred2.PseudoVal LDpred1.MultiPRS 0.194 0.232 -0.038 2.20e-08 0.190 0.231 -0.041 5.68e-13
T2D DBSLMM.PseudoVal LDpred1.MultiPRS 0.229 0.232 -0.003 6.74e-01 0.226 0.231 -0.005 2.77e-01
T2D LDpred2.MultiPRS LDpred1.MultiPRS 0.242 0.232 0.010 1.47e-01 0.240 0.231 0.009 7.28e-03
T2D SBLUP.Inf LDpred1.MultiPRS 0.189 0.232 -0.043 3.54e-10 0.184 0.231 -0.047 6.09e-15
T2D All.MultiPRS LDpred1.Inf 0.242 0.187 0.055 9.62e-16 0.242 0.184 0.057 4.48e-18
T2D LDpred2.PseudoVal LDpred1.Inf 0.194 0.187 0.007 1.43e-09 0.190 0.184 0.005 1.43e-02
T2D SBayesR.PseudoVal LDpred1.Inf 0.226 0.187 0.039 9.83e-20 0.227 0.184 0.043 4.40e-07
T2D LDpred2.MultiPRS LDpred1.Inf 0.242 0.187 0.055 7.95e-16 0.240 0.184 0.056 3.13e-17
T2D PRScs.PseudoVal LDpred1.Inf 0.226 0.187 0.039 3.13e-59 0.226 0.184 0.042 3.43e-18
T2D LDpred1.Inf LDpred1.Inf 0.187 0.187 0.000 1.00e+00 0.184 0.184 0.000 1.00e+00
T2D pT+clump.10FCVal LDpred1.Inf 0.167 0.187 -0.020 4.17e-04 0.173 0.184 -0.012 3.00e-01
T2D PRScs.MultiPRS LDpred1.Inf 0.235 0.187 0.048 2.98e-12 0.237 0.184 0.053 8.26e-20
T2D lassosum.PseudoVal LDpred1.Inf 0.206 0.187 0.019 2.56e-04 0.214 0.184 0.030 2.87e-03
T2D pT+clump.MultiPRS LDpred1.Inf 0.212 0.187 0.025 3.52e-04 0.215 0.184 0.031 1.76e-04
T2D LDpred1.MultiPRS LDpred1.Inf 0.232 0.187 0.045 4.85e-11 0.231 0.184 0.047 3.90e-16
T2D PRScs.10FCVal LDpred1.Inf 0.228 0.187 0.041 1.10e-60 0.227 0.184 0.043 5.70e-19
T2D LDpred2.Inf LDpred1.Inf 0.189 0.187 0.002 5.99e-02 0.185 0.184 0.001 7.02e-01
T2D SBLUP.Inf LDpred1.Inf 0.189 0.187 0.002 5.11e-02 0.184 0.184 0.000 9.57e-01
T2D DBSLMM.PseudoVal LDpred1.Inf 0.229 0.187 0.042 4.35e-48 0.226 0.184 0.042 2.33e-13
T2D lassosum.MultiPRS LDpred1.Inf 0.237 0.187 0.050 1.74e-13 0.240 0.184 0.056 2.15e-18
T2D LDpred1.10FCVal LDpred1.Inf 0.232 0.187 0.045 2.88e-57 0.230 0.184 0.046 1.11e-16
T2D lassosum.10FCVal LDpred1.Inf 0.214 0.187 0.027 3.27e-15 0.216 0.184 0.031 2.25e-06
T2D LDpred2.10FCVal LDpred1.Inf 0.237 0.187 0.050 1.11e-61 0.238 0.184 0.053 9.48e-20
T2D LDpred1.Inf LDpred1.10FCVal 0.187 0.232 -0.045 2.88e-57 0.184 0.230 -0.046 1.11e-16
T2D PRScs.MultiPRS LDpred1.10FCVal 0.235 0.232 0.003 6.97e-01 0.237 0.230 0.007 1.19e-02
T2D LDpred1.10FCVal LDpred1.10FCVal 0.232 0.232 0.000 1.00e+00 0.230 0.230 0.000 1.00e+00
T2D All.MultiPRS LDpred1.10FCVal 0.242 0.232 0.010 1.43e-01 0.242 0.230 0.012 5.10e-04
T2D SBayesR.PseudoVal LDpred1.10FCVal 0.226 0.232 -0.006 1.62e-02 0.227 0.230 -0.003 5.42e-01
T2D DBSLMM.PseudoVal LDpred1.10FCVal 0.229 0.232 -0.003 1.96e-01 0.226 0.230 -0.004 3.65e-01
T2D pT+clump.MultiPRS LDpred1.10FCVal 0.212 0.232 -0.020 2.87e-03 0.215 0.230 -0.015 3.77e-03
T2D lassosum.MultiPRS LDpred1.10FCVal 0.237 0.232 0.005 4.23e-01 0.240 0.230 0.010 5.87e-04
T2D PRScs.10FCVal LDpred1.10FCVal 0.228 0.232 -0.004 1.19e-02 0.227 0.230 -0.003 3.63e-01
T2D lassosum.10FCVal LDpred1.10FCVal 0.214 0.232 -0.018 3.68e-22 0.216 0.230 -0.014 1.07e-04
T2D SBLUP.Inf LDpred1.10FCVal 0.189 0.232 -0.043 2.35e-47 0.184 0.230 -0.046 2.36e-15
T2D LDpred2.PseudoVal LDpred1.10FCVal 0.194 0.232 -0.038 3.51e-41 0.190 0.230 -0.041 2.89e-13
T2D pT+clump.10FCVal LDpred1.10FCVal 0.167 0.232 -0.065 2.93e-57 0.173 0.230 -0.058 1.33e-12
T2D LDpred2.MultiPRS LDpred1.10FCVal 0.242 0.232 0.010 1.41e-01 0.240 0.230 0.010 4.09e-03
T2D PRScs.PseudoVal LDpred1.10FCVal 0.226 0.232 -0.005 8.16e-04 0.226 0.230 -0.004 1.90e-01
T2D LDpred2.10FCVal LDpred1.10FCVal 0.237 0.232 0.005 1.18e-05 0.238 0.230 0.008 3.40e-04
T2D LDpred1.MultiPRS LDpred1.10FCVal 0.232 0.232 0.000 9.86e-01 0.231 0.230 0.001 8.06e-02
T2D LDpred2.Inf LDpred1.10FCVal 0.189 0.232 -0.043 1.12e-46 0.185 0.230 -0.045 1.15e-14
T2D lassosum.PseudoVal LDpred1.10FCVal 0.206 0.232 -0.026 1.05e-19 0.214 0.230 -0.016 5.85e-03
T2D LDpred1.Inf LDpred2.MultiPRS 0.187 0.242 -0.055 7.95e-16 0.184 0.240 -0.056 3.13e-17
T2D DBSLMM.PseudoVal LDpred2.MultiPRS 0.229 0.242 -0.013 6.08e-02 0.226 0.240 -0.014 2.71e-04
T2D SBLUP.Inf LDpred2.MultiPRS 0.189 0.242 -0.053 9.26e-15 0.184 0.240 -0.056 1.55e-17
T2D LDpred2.Inf LDpred2.MultiPRS 0.189 0.242 -0.053 9.61e-15 0.185 0.240 -0.055 3.12e-17
T2D pT+clump.10FCVal LDpred2.MultiPRS 0.167 0.242 -0.075 7.08e-28 0.173 0.240 -0.067 1.49e-18
T2D LDpred2.10FCVal LDpred2.MultiPRS 0.237 0.242 -0.005 4.43e-01 0.238 0.240 -0.002 4.18e-01
T2D PRScs.PseudoVal LDpred2.MultiPRS 0.226 0.242 -0.015 2.30e-02 0.226 0.240 -0.014 4.27e-04
T2D LDpred1.10FCVal LDpred2.MultiPRS 0.232 0.242 -0.010 1.41e-01 0.230 0.240 -0.010 4.09e-03
T2D All.MultiPRS LDpred2.MultiPRS 0.242 0.242 0.000 9.96e-01 0.242 0.240 0.002 2.13e-01
T2D SBayesR.PseudoVal LDpred2.MultiPRS 0.226 0.242 -0.016 2.13e-02 0.227 0.240 -0.013 2.16e-03
T2D lassosum.10FCVal LDpred2.MultiPRS 0.214 0.242 -0.028 3.19e-05 0.216 0.240 -0.024 1.59e-06
T2D pT+clump.MultiPRS LDpred2.MultiPRS 0.212 0.242 -0.030 8.13e-06 0.215 0.240 -0.025 7.69e-07
T2D lassosum.MultiPRS LDpred2.MultiPRS 0.237 0.242 -0.005 5.03e-01 0.240 0.240 0.000 9.04e-01
T2D PRScs.10FCVal LDpred2.MultiPRS 0.228 0.242 -0.014 3.84e-02 0.227 0.240 -0.013 1.28e-03
T2D PRScs.MultiPRS LDpred2.MultiPRS 0.235 0.242 -0.007 2.78e-01 0.237 0.240 -0.003 3.51e-01
T2D lassosum.PseudoVal LDpred2.MultiPRS 0.206 0.242 -0.036 9.62e-08 0.214 0.240 -0.026 7.12e-06
T2D LDpred2.PseudoVal LDpred2.MultiPRS 0.194 0.242 -0.048 1.55e-12 0.190 0.240 -0.050 6.01e-16
T2D LDpred1.MultiPRS LDpred2.MultiPRS 0.232 0.242 -0.010 1.47e-01 0.231 0.240 -0.009 7.28e-03
T2D LDpred2.MultiPRS LDpred2.MultiPRS 0.242 0.242 0.000 1.00e+00 0.240 0.240 0.000 1.00e+00
T2D LDpred1.Inf LDpred2.10FCVal 0.187 0.237 -0.050 1.11e-61 0.184 0.238 -0.053 9.48e-20
T2D PRScs.MultiPRS LDpred2.10FCVal 0.235 0.237 -0.002 7.55e-01 0.237 0.238 -0.001 7.47e-01
T2D LDpred2.MultiPRS LDpred2.10FCVal 0.242 0.237 0.005 4.43e-01 0.240 0.238 0.002 4.18e-01
T2D PRScs.PseudoVal LDpred2.10FCVal 0.226 0.237 -0.010 3.37e-11 0.226 0.238 -0.012 1.00e-04
T2D LDpred2.10FCVal LDpred2.10FCVal 0.237 0.237 0.000 1.00e+00 0.238 0.238 0.000 1.00e+00
T2D lassosum.MultiPRS LDpred2.10FCVal 0.237 0.237 0.001 9.22e-01 0.240 0.238 0.003 2.78e-01
T2D LDpred1.10FCVal LDpred2.10FCVal 0.232 0.237 -0.005 1.18e-05 0.230 0.238 -0.008 3.40e-04
T2D All.MultiPRS LDpred2.10FCVal 0.242 0.237 0.005 4.46e-01 0.242 0.238 0.004 1.45e-01
T2D SBayesR.PseudoVal LDpred2.10FCVal 0.226 0.237 -0.010 1.45e-06 0.227 0.238 -0.010 1.44e-02
T2D DBSLMM.PseudoVal LDpred2.10FCVal 0.229 0.237 -0.008 8.86e-05 0.226 0.238 -0.011 2.47e-03
T2D pT+clump.MultiPRS LDpred2.10FCVal 0.212 0.237 -0.025 2.32e-04 0.215 0.238 -0.023 6.26e-06
T2D lassosum.PseudoVal LDpred2.10FCVal 0.206 0.237 -0.031 1.68e-30 0.214 0.238 -0.023 1.38e-05
T2D PRScs.10FCVal LDpred2.10FCVal 0.228 0.237 -0.009 3.41e-09 0.227 0.238 -0.011 4.46e-04
T2D lassosum.10FCVal LDpred2.10FCVal 0.214 0.237 -0.023 1.36e-34 0.216 0.238 -0.022 4.27e-09
T2D SBLUP.Inf LDpred2.10FCVal 0.189 0.237 -0.048 5.94e-58 0.184 0.238 -0.054 3.32e-20
T2D LDpred2.PseudoVal LDpred2.10FCVal 0.194 0.237 -0.043 2.84e-54 0.190 0.238 -0.048 6.64e-19
T2D pT+clump.10FCVal LDpred2.10FCVal 0.167 0.237 -0.070 4.42e-69 0.173 0.238 -0.065 2.26e-16
T2D LDpred2.Inf LDpred2.10FCVal 0.189 0.237 -0.048 1.05e-58 0.185 0.238 -0.053 6.63e-20
T2D LDpred1.MultiPRS LDpred2.10FCVal 0.232 0.237 -0.005 4.93e-01 0.231 0.238 -0.007 8.48e-04
T2D lassosum.10FCVal LDpred2.PseudoVal 0.214 0.194 0.020 8.22e-10 0.216 0.190 0.026 4.30e-05
T2D SBLUP.Inf LDpred2.PseudoVal 0.189 0.194 -0.005 6.30e-16 0.184 0.190 -0.005 1.98e-06
T2D SBayesR.PseudoVal LDpred2.PseudoVal 0.226 0.194 0.033 7.95e-15 0.227 0.190 0.038 4.75e-06
T2D All.MultiPRS LDpred2.PseudoVal 0.242 0.194 0.048 1.79e-12 0.242 0.190 0.052 6.78e-17
T2D PRScs.PseudoVal LDpred2.PseudoVal 0.226 0.194 0.033 1.52e-47 0.226 0.190 0.036 2.87e-16
T2D lassosum.MultiPRS LDpred2.PseudoVal 0.237 0.194 0.044 1.67e-10 0.240 0.190 0.051 7.52e-17
T2D PRScs.MultiPRS LDpred2.PseudoVal 0.235 0.194 0.041 2.05e-09 0.237 0.190 0.047 2.24e-18
T2D LDpred2.MultiPRS LDpred2.PseudoVal 0.242 0.194 0.048 1.55e-12 0.240 0.190 0.050 6.01e-16
T2D PRScs.10FCVal LDpred2.PseudoVal 0.228 0.194 0.034 3.45e-50 0.227 0.190 0.038 2.84e-17
T2D LDpred2.PseudoVal LDpred2.PseudoVal 0.194 0.194 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
T2D pT+clump.MultiPRS LDpred2.PseudoVal 0.212 0.194 0.018 9.36e-03 0.215 0.190 0.025 1.59e-03
T2D pT+clump.10FCVal LDpred2.PseudoVal 0.167 0.194 -0.027 1.72e-06 0.173 0.190 -0.017 1.27e-01
T2D lassosum.PseudoVal LDpred2.PseudoVal 0.206 0.194 0.012 1.71e-02 0.214 0.190 0.025 1.22e-02
T2D LDpred1.Inf LDpred2.PseudoVal 0.187 0.194 -0.007 1.43e-09 0.184 0.190 -0.005 1.43e-02
T2D LDpred1.MultiPRS LDpred2.PseudoVal 0.232 0.194 0.038 2.20e-08 0.231 0.190 0.041 5.68e-13
T2D LDpred1.10FCVal LDpred2.PseudoVal 0.232 0.194 0.038 3.51e-41 0.230 0.190 0.041 2.89e-13
T2D LDpred2.Inf LDpred2.PseudoVal 0.189 0.194 -0.005 1.74e-18 0.185 0.190 -0.004 1.65e-05
T2D LDpred2.10FCVal LDpred2.PseudoVal 0.237 0.194 0.043 2.84e-54 0.238 0.190 0.048 6.64e-19
T2D DBSLMM.PseudoVal LDpred2.PseudoVal 0.229 0.194 0.035 2.16e-38 0.226 0.190 0.037 1.28e-11
T2D pT+clump.MultiPRS LDpred2.Inf 0.212 0.189 0.023 1.07e-03 0.215 0.185 0.030 2.73e-04
T2D lassosum.MultiPRS LDpred2.Inf 0.237 0.189 0.048 1.60e-12 0.240 0.185 0.055 6.80e-18
T2D SBayesR.PseudoVal LDpred2.Inf 0.226 0.189 0.037 1.03e-17 0.227 0.185 0.042 7.51e-07
T2D All.MultiPRS LDpred2.Inf 0.242 0.189 0.053 1.10e-14 0.242 0.185 0.057 3.30e-18
T2D SBLUP.Inf LDpred2.Inf 0.189 0.189 0.000 9.69e-01 0.184 0.185 -0.001 2.78e-01
T2D LDpred2.PseudoVal LDpred2.Inf 0.194 0.189 0.005 1.74e-18 0.190 0.185 0.004 1.65e-05
T2D PRScs.MultiPRS LDpred2.Inf 0.235 0.189 0.046 2.51e-11 0.237 0.185 0.052 2.32e-19
T2D LDpred2.MultiPRS LDpred2.Inf 0.242 0.189 0.053 9.61e-15 0.240 0.185 0.055 3.12e-17
T2D PRScs.10FCVal LDpred2.Inf 0.228 0.189 0.039 2.81e-57 0.227 0.185 0.042 4.31e-19
T2D LDpred1.Inf LDpred2.Inf 0.187 0.189 -0.002 5.99e-02 0.184 0.185 -0.001 7.02e-01
T2D LDpred1.MultiPRS LDpred2.Inf 0.232 0.189 0.043 3.59e-10 0.231 0.185 0.046 2.78e-14
T2D pT+clump.10FCVal LDpred2.Inf 0.167 0.189 -0.022 1.07e-04 0.173 0.185 -0.013 2.70e-01
T2D lassosum.PseudoVal LDpred2.Inf 0.206 0.189 0.017 1.33e-03 0.214 0.185 0.029 4.15e-03
T2D PRScs.PseudoVal LDpred2.Inf 0.226 0.189 0.037 3.50e-55 0.226 0.185 0.041 2.65e-18
T2D DBSLMM.PseudoVal LDpred2.Inf 0.229 0.189 0.040 1.66e-45 0.226 0.185 0.041 2.09e-13
T2D LDpred1.10FCVal LDpred2.Inf 0.232 0.189 0.043 1.12e-46 0.230 0.185 0.045 1.15e-14
T2D LDpred2.Inf LDpred2.Inf 0.189 0.189 0.000 1.00e+00 0.185 0.185 0.000 1.00e+00
T2D lassosum.10FCVal LDpred2.Inf 0.214 0.189 0.025 4.13e-13 0.216 0.185 0.031 4.35e-06
T2D LDpred2.10FCVal LDpred2.Inf 0.237 0.189 0.048 1.05e-58 0.238 0.185 0.053 6.63e-20
T2D PRScs.10FCVal PRScs.MultiPRS 0.228 0.235 -0.007 3.22e-01 0.227 0.237 -0.010 2.97e-05
T2D LDpred1.10FCVal PRScs.MultiPRS 0.232 0.235 -0.003 6.97e-01 0.230 0.237 -0.007 1.19e-02
T2D lassosum.MultiPRS PRScs.MultiPRS 0.237 0.235 0.003 6.81e-01 0.240 0.237 0.003 2.05e-01
T2D LDpred2.MultiPRS PRScs.MultiPRS 0.242 0.235 0.007 2.78e-01 0.240 0.237 0.003 3.51e-01
T2D All.MultiPRS PRScs.MultiPRS 0.242 0.235 0.007 2.83e-01 0.242 0.237 0.005 1.15e-01
T2D PRScs.PseudoVal PRScs.MultiPRS 0.226 0.235 -0.008 2.32e-01 0.226 0.237 -0.011 6.99e-06
T2D LDpred1.MultiPRS PRScs.MultiPRS 0.232 0.235 -0.003 7.10e-01 0.231 0.237 -0.006 2.13e-02
T2D pT+clump.MultiPRS PRScs.MultiPRS 0.212 0.235 -0.023 7.51e-04 0.215 0.237 -0.022 1.34e-05
T2D lassosum.PseudoVal PRScs.MultiPRS 0.206 0.235 -0.029 2.30e-05 0.214 0.237 -0.023 9.22e-05
T2D SBayesR.PseudoVal PRScs.MultiPRS 0.226 0.235 -0.008 2.23e-01 0.227 0.237 -0.010 3.18e-02
T2D DBSLMM.PseudoVal PRScs.MultiPRS 0.229 0.235 -0.005 4.27e-01 0.226 0.237 -0.011 2.46e-03
T2D SBLUP.Inf PRScs.MultiPRS 0.189 0.235 -0.046 2.48e-11 0.184 0.237 -0.053 3.88e-20
T2D LDpred2.Inf PRScs.MultiPRS 0.189 0.235 -0.046 2.51e-11 0.185 0.237 -0.052 2.32e-19
T2D pT+clump.10FCVal PRScs.MultiPRS 0.167 0.235 -0.068 6.35e-23 0.173 0.237 -0.064 5.15e-15
T2D LDpred2.10FCVal PRScs.MultiPRS 0.237 0.235 0.002 7.55e-01 0.238 0.237 0.001 7.47e-01
T2D lassosum.10FCVal PRScs.MultiPRS 0.214 0.235 -0.021 2.13e-03 0.216 0.237 -0.021 1.55e-06
T2D LDpred2.PseudoVal PRScs.MultiPRS 0.194 0.235 -0.041 2.05e-09 0.190 0.237 -0.047 2.24e-18
T2D LDpred1.Inf PRScs.MultiPRS 0.187 0.235 -0.048 2.98e-12 0.184 0.237 -0.053 8.26e-20
T2D PRScs.MultiPRS PRScs.MultiPRS 0.235 0.235 0.000 1.00e+00 0.237 0.237 0.000 1.00e+00
T2D LDpred2.PseudoVal PRScs.10FCVal 0.194 0.228 -0.034 3.45e-50 0.190 0.227 -0.038 2.84e-17
T2D PRScs.10FCVal PRScs.10FCVal 0.228 0.228 0.000 1.00e+00 0.227 0.227 0.000 1.00e+00
T2D LDpred2.MultiPRS PRScs.10FCVal 0.242 0.228 0.014 3.84e-02 0.240 0.227 0.013 1.28e-03
T2D pT+clump.MultiPRS PRScs.10FCVal 0.212 0.228 -0.016 1.74e-02 0.215 0.227 -0.012 3.72e-02
T2D LDpred1.Inf PRScs.10FCVal 0.187 0.228 -0.041 1.10e-60 0.184 0.227 -0.043 5.70e-19
T2D LDpred1.MultiPRS PRScs.10FCVal 0.232 0.228 0.004 5.37e-01 0.231 0.227 0.004 2.60e-01
T2D pT+clump.10FCVal PRScs.10FCVal 0.167 0.228 -0.061 3.89e-41 0.173 0.227 -0.055 1.71e-09
T2D lassosum.PseudoVal PRScs.10FCVal 0.206 0.228 -0.022 2.96e-10 0.214 0.227 -0.013 6.75e-02
T2D PRScs.PseudoVal PRScs.10FCVal 0.226 0.228 -0.001 3.63e-01 0.226 0.227 -0.001 6.57e-01
T2D DBSLMM.PseudoVal PRScs.10FCVal 0.229 0.228 0.001 5.03e-01 0.226 0.227 -0.001 8.31e-01
T2D SBLUP.Inf PRScs.10FCVal 0.189 0.228 -0.039 1.65e-58 0.184 0.227 -0.043 3.06e-20
T2D LDpred2.Inf PRScs.10FCVal 0.189 0.228 -0.039 2.81e-57 0.185 0.227 -0.042 4.31e-19
T2D lassosum.10FCVal PRScs.10FCVal 0.214 0.228 -0.014 7.41e-10 0.216 0.227 -0.012 1.22e-02
T2D LDpred2.10FCVal PRScs.10FCVal 0.237 0.228 0.009 3.41e-09 0.238 0.227 0.011 4.46e-04
T2D lassosum.MultiPRS PRScs.10FCVal 0.237 0.228 0.010 1.61e-01 0.240 0.227 0.013 2.89e-04
T2D LDpred1.10FCVal PRScs.10FCVal 0.232 0.228 0.004 1.19e-02 0.230 0.227 0.003 3.63e-01
T2D All.MultiPRS PRScs.10FCVal 0.242 0.228 0.014 3.88e-02 0.242 0.227 0.015 1.01e-04
T2D SBayesR.PseudoVal PRScs.10FCVal 0.226 0.228 -0.002 5.85e-01 0.227 0.227 0.000 9.88e-01
T2D PRScs.MultiPRS PRScs.10FCVal 0.235 0.228 0.007 3.22e-01 0.237 0.227 0.010 2.97e-05
T2D All.MultiPRS PRScs.PseudoVal 0.242 0.226 0.015 2.34e-02 0.242 0.226 0.016 4.31e-05
T2D pT+clump.MultiPRS PRScs.PseudoVal 0.212 0.226 -0.015 2.97e-02 0.215 0.226 -0.011 6.43e-02
T2D LDpred2.PseudoVal PRScs.PseudoVal 0.194 0.226 -0.033 1.52e-47 0.190 0.226 -0.036 2.87e-16
T2D SBayesR.PseudoVal PRScs.PseudoVal 0.226 0.226 0.000 9.47e-01 0.227 0.226 0.001 8.05e-01
T2D LDpred2.MultiPRS PRScs.PseudoVal 0.242 0.226 0.015 2.30e-02 0.240 0.226 0.014 4.27e-04
T2D SBLUP.Inf PRScs.PseudoVal 0.189 0.226 -0.037 2.05e-56 0.184 0.226 -0.042 2.31e-19
T2D LDpred1.Inf PRScs.PseudoVal 0.187 0.226 -0.039 3.13e-59 0.184 0.226 -0.042 3.43e-18
T2D PRScs.10FCVal PRScs.PseudoVal 0.228 0.226 0.001 3.63e-01 0.227 0.226 0.001 6.57e-01
T2D LDpred2.Inf PRScs.PseudoVal 0.189 0.226 -0.037 3.50e-55 0.185 0.226 -0.041 2.65e-18
T2D PRScs.PseudoVal PRScs.PseudoVal 0.226 0.226 0.000 1.00e+00 0.226 0.226 0.000 1.00e+00
T2D LDpred2.10FCVal PRScs.PseudoVal 0.237 0.226 0.010 3.37e-11 0.238 0.226 0.012 1.00e-04
T2D pT+clump.10FCVal PRScs.PseudoVal 0.167 0.226 -0.060 7.34e-39 0.173 0.226 -0.053 4.90e-09
T2D PRScs.MultiPRS PRScs.PseudoVal 0.235 0.226 0.008 2.32e-01 0.237 0.226 0.011 6.99e-06
T2D lassosum.PseudoVal PRScs.PseudoVal 0.206 0.226 -0.021 5.80e-09 0.214 0.226 -0.012 1.03e-01
T2D lassosum.10FCVal PRScs.PseudoVal 0.214 0.226 -0.013 4.14e-08 0.216 0.226 -0.010 2.86e-02
T2D LDpred1.MultiPRS PRScs.PseudoVal 0.232 0.226 0.006 4.13e-01 0.231 0.226 0.005 1.29e-01
T2D lassosum.MultiPRS PRScs.PseudoVal 0.237 0.226 0.011 1.09e-01 0.240 0.226 0.014 7.36e-05
T2D LDpred1.10FCVal PRScs.PseudoVal 0.232 0.226 0.005 8.16e-04 0.230 0.226 0.004 1.90e-01
T2D DBSLMM.PseudoVal PRScs.PseudoVal 0.229 0.226 0.003 1.75e-01 0.226 0.226 0.000 9.03e-01
T2D All.MultiPRS pT+clump.MultiPRS 0.242 0.212 0.030 8.65e-06 0.242 0.215 0.027 1.25e-07
T2D SBayesR.PseudoVal pT+clump.MultiPRS 0.226 0.212 0.015 3.14e-02 0.227 0.215 0.012 2.29e-02
T2D LDpred1.MultiPRS pT+clump.MultiPRS 0.232 0.212 0.020 2.67e-03 0.231 0.215 0.016 1.96e-03
T2D pT+clump.MultiPRS pT+clump.MultiPRS 0.212 0.212 0.000 1.00e+00 0.215 0.215 0.000 1.00e+00
T2D lassosum.PseudoVal pT+clump.MultiPRS 0.206 0.212 -0.006 3.79e-01 0.214 0.215 -0.001 9.15e-01
T2D PRScs.10FCVal pT+clump.MultiPRS 0.228 0.212 0.016 1.74e-02 0.227 0.215 0.012 3.72e-02
T2D DBSLMM.PseudoVal pT+clump.MultiPRS 0.229 0.212 0.018 1.01e-02 0.226 0.215 0.011 2.49e-02
T2D SBLUP.Inf pT+clump.MultiPRS 0.189 0.212 -0.023 1.06e-03 0.184 0.215 -0.031 1.59e-04
T2D LDpred2.Inf pT+clump.MultiPRS 0.189 0.212 -0.023 1.07e-03 0.185 0.215 -0.030 2.73e-04
T2D pT+clump.10FCVal pT+clump.MultiPRS 0.167 0.212 -0.045 8.52e-11 0.173 0.215 -0.042 2.98e-11
T2D LDpred2.10FCVal pT+clump.MultiPRS 0.237 0.212 0.025 2.32e-04 0.238 0.215 0.023 6.26e-06
T2D PRScs.PseudoVal pT+clump.MultiPRS 0.226 0.212 0.015 2.97e-02 0.226 0.215 0.011 6.43e-02
T2D LDpred1.10FCVal pT+clump.MultiPRS 0.232 0.212 0.020 2.87e-03 0.230 0.215 0.015 3.77e-03
T2D LDpred1.Inf pT+clump.MultiPRS 0.187 0.212 -0.025 3.52e-04 0.184 0.215 -0.031 1.76e-04
T2D PRScs.MultiPRS pT+clump.MultiPRS 0.235 0.212 0.023 7.51e-04 0.237 0.215 0.022 1.34e-05
T2D lassosum.10FCVal pT+clump.MultiPRS 0.214 0.212 0.002 7.70e-01 0.216 0.215 0.001 9.07e-01
T2D LDpred2.PseudoVal pT+clump.MultiPRS 0.194 0.212 -0.018 9.36e-03 0.190 0.215 -0.025 1.59e-03
T2D lassosum.MultiPRS pT+clump.MultiPRS 0.237 0.212 0.026 1.46e-04 0.240 0.215 0.025 5.80e-08
T2D LDpred2.MultiPRS pT+clump.MultiPRS 0.242 0.212 0.030 8.13e-06 0.240 0.215 0.025 7.69e-07
T2D LDpred2.10FCVal pT+clump.10FCVal 0.237 0.167 0.070 4.42e-69 0.238 0.173 0.065 2.26e-16
T2D pT+clump.MultiPRS pT+clump.10FCVal 0.212 0.167 0.045 8.52e-11 0.215 0.173 0.042 2.98e-11
T2D LDpred2.Inf pT+clump.10FCVal 0.189 0.167 0.022 1.07e-04 0.185 0.173 0.013 2.70e-01
T2D SBayesR.PseudoVal pT+clump.10FCVal 0.226 0.167 0.059 4.88e-69 0.227 0.173 0.055 9.71e-16
T2D PRScs.MultiPRS pT+clump.10FCVal 0.235 0.167 0.068 6.35e-23 0.237 0.173 0.064 5.15e-15
T2D SBLUP.Inf pT+clump.10FCVal 0.189 0.167 0.022 1.08e-04 0.184 0.173 0.012 3.07e-01
T2D lassosum.MultiPRS pT+clump.10FCVal 0.237 0.167 0.071 5.84e-25 0.240 0.173 0.068 6.94e-20
T2D PRScs.10FCVal pT+clump.10FCVal 0.228 0.167 0.061 3.89e-41 0.227 0.173 0.055 1.71e-09
T2D LDpred2.MultiPRS pT+clump.10FCVal 0.242 0.167 0.075 7.08e-28 0.240 0.173 0.067 1.49e-18
T2D lassosum.10FCVal pT+clump.10FCVal 0.214 0.167 0.047 2.14e-26 0.216 0.173 0.043 8.50e-07
T2D LDpred2.PseudoVal pT+clump.10FCVal 0.194 0.167 0.027 1.72e-06 0.190 0.173 0.017 1.27e-01
T2D LDpred1.MultiPRS pT+clump.10FCVal 0.232 0.167 0.065 2.36e-21 0.231 0.173 0.058 3.83e-13
T2D pT+clump.10FCVal pT+clump.10FCVal 0.167 0.167 0.000 1.00e+00 0.173 0.173 0.000 1.00e+00
T2D All.MultiPRS pT+clump.10FCVal 0.242 0.167 0.075 7.70e-28 0.242 0.173 0.069 5.83e-19
T2D LDpred1.Inf pT+clump.10FCVal 0.187 0.167 0.020 4.17e-04 0.184 0.173 0.012 3.00e-01
T2D DBSLMM.PseudoVal pT+clump.10FCVal 0.229 0.167 0.062 1.53e-47 0.226 0.173 0.054 2.59e-10
T2D LDpred1.10FCVal pT+clump.10FCVal 0.232 0.167 0.065 2.93e-57 0.230 0.173 0.058 1.33e-12
T2D lassosum.PseudoVal pT+clump.10FCVal 0.206 0.167 0.039 3.94e-34 0.214 0.173 0.042 4.23e-11
T2D PRScs.PseudoVal pT+clump.10FCVal 0.226 0.167 0.060 7.34e-39 0.226 0.173 0.053 4.90e-09
T2D pT+clump.MultiPRS SBayesR.PseudoVal 0.212 0.226 -0.015 3.14e-02 0.215 0.227 -0.012 2.29e-02
T2D LDpred1.10FCVal SBayesR.PseudoVal 0.232 0.226 0.006 1.62e-02 0.230 0.227 0.003 5.42e-01
T2D PRScs.10FCVal SBayesR.PseudoVal 0.228 0.226 0.002 5.85e-01 0.227 0.227 0.000 9.88e-01
T2D LDpred2.10FCVal SBayesR.PseudoVal 0.237 0.226 0.010 1.45e-06 0.238 0.227 0.010 1.44e-02
T2D lassosum.10FCVal SBayesR.PseudoVal 0.214 0.226 -0.013 1.35e-05 0.216 0.227 -0.012 4.36e-02
T2D LDpred2.PseudoVal SBayesR.PseudoVal 0.194 0.226 -0.033 7.95e-15 0.190 0.227 -0.038 4.75e-06
T2D lassosum.MultiPRS SBayesR.PseudoVal 0.237 0.226 0.011 1.02e-01 0.240 0.227 0.013 1.37e-03
T2D LDpred2.MultiPRS SBayesR.PseudoVal 0.242 0.226 0.016 2.13e-02 0.240 0.227 0.013 2.16e-03
T2D All.MultiPRS SBayesR.PseudoVal 0.242 0.226 0.016 2.17e-02 0.242 0.227 0.014 2.02e-04
T2D PRScs.PseudoVal SBayesR.PseudoVal 0.226 0.226 0.000 9.47e-01 0.226 0.227 -0.001 8.05e-01
T2D LDpred1.MultiPRS SBayesR.PseudoVal 0.232 0.226 0.006 3.96e-01 0.231 0.227 0.004 4.27e-01
T2D pT+clump.10FCVal SBayesR.PseudoVal 0.167 0.226 -0.059 4.88e-69 0.173 0.227 -0.055 9.71e-16
T2D lassosum.PseudoVal SBayesR.PseudoVal 0.206 0.226 -0.021 1.83e-18 0.214 0.227 -0.013 5.67e-03
T2D SBayesR.PseudoVal SBayesR.PseudoVal 0.226 0.226 0.000 1.00e+00 0.227 0.227 0.000 1.00e+00
T2D DBSLMM.PseudoVal SBayesR.PseudoVal 0.229 0.226 0.003 2.83e-01 0.226 0.227 -0.001 8.61e-01
T2D SBLUP.Inf SBayesR.PseudoVal 0.189 0.226 -0.037 9.69e-18 0.184 0.227 -0.043 4.42e-07
T2D LDpred2.Inf SBayesR.PseudoVal 0.189 0.226 -0.037 1.03e-17 0.185 0.227 -0.042 7.51e-07
T2D LDpred1.Inf SBayesR.PseudoVal 0.187 0.226 -0.039 9.83e-20 0.184 0.227 -0.043 4.40e-07
T2D PRScs.MultiPRS SBayesR.PseudoVal 0.235 0.226 0.008 2.23e-01 0.237 0.227 0.010 3.18e-02
T2D LDpred2.10FCVal SBLUP.Inf 0.237 0.189 0.048 5.94e-58 0.238 0.184 0.054 3.32e-20
T2D PRScs.PseudoVal SBLUP.Inf 0.226 0.189 0.037 2.05e-56 0.226 0.184 0.042 2.31e-19
T2D LDpred1.10FCVal SBLUP.Inf 0.232 0.189 0.043 2.35e-47 0.230 0.184 0.046 2.36e-15
T2D LDpred2.Inf SBLUP.Inf 0.189 0.189 0.000 9.69e-01 0.185 0.184 0.001 2.78e-01
T2D SBayesR.PseudoVal SBLUP.Inf 0.226 0.189 0.037 9.69e-18 0.227 0.184 0.043 4.42e-07
T2D lassosum.10FCVal SBLUP.Inf 0.214 0.189 0.025 3.02e-13 0.216 0.184 0.031 1.96e-06
T2D pT+clump.MultiPRS SBLUP.Inf 0.212 0.189 0.023 1.06e-03 0.215 0.184 0.031 1.59e-04
T2D lassosum.MultiPRS SBLUP.Inf 0.237 0.189 0.048 1.59e-12 0.240 0.184 0.056 1.38e-18
T2D PRScs.10FCVal SBLUP.Inf 0.228 0.189 0.039 1.65e-58 0.227 0.184 0.043 3.06e-20
T2D PRScs.MultiPRS SBLUP.Inf 0.235 0.189 0.046 2.48e-11 0.237 0.184 0.053 3.88e-20
T2D LDpred1.MultiPRS SBLUP.Inf 0.232 0.189 0.043 3.54e-10 0.231 0.184 0.047 6.09e-15
T2D LDpred2.PseudoVal SBLUP.Inf 0.194 0.189 0.005 6.30e-16 0.190 0.184 0.005 1.98e-06
T2D LDpred1.Inf SBLUP.Inf 0.187 0.189 -0.002 5.11e-02 0.184 0.184 0.000 9.57e-01
T2D LDpred2.MultiPRS SBLUP.Inf 0.242 0.189 0.053 9.26e-15 0.240 0.184 0.056 1.55e-17
T2D All.MultiPRS SBLUP.Inf 0.242 0.189 0.053 1.08e-14 0.242 0.184 0.057 1.24e-18
T2D SBLUP.Inf SBLUP.Inf 0.189 0.189 0.000 1.00e+00 0.184 0.184 0.000 1.00e+00
T2D DBSLMM.PseudoVal SBLUP.Inf 0.229 0.189 0.040 4.70e-46 0.226 0.184 0.042 4.78e-14
T2D pT+clump.10FCVal SBLUP.Inf 0.167 0.189 -0.022 1.08e-04 0.173 0.184 -0.012 3.07e-01
T2D lassosum.PseudoVal SBLUP.Inf 0.206 0.189 0.017 1.30e-03 0.214 0.184 0.030 3.09e-03
CAD LDpred2.PseudoVal All.MultiPRS 0.107 0.191 -0.084 8.32e-36 0.111 0.190 -0.079 5.04e-17
CAD pT+clump.10FCVal All.MultiPRS 0.135 0.191 -0.056 2.96e-17 0.134 0.190 -0.056 7.05e-13
CAD LDpred2.MultiPRS All.MultiPRS 0.192 0.191 0.001 9.15e-01 0.186 0.190 -0.004 3.49e-02
CAD PRScs.PseudoVal All.MultiPRS 0.181 0.191 -0.010 1.28e-01 0.182 0.190 -0.008 2.50e-02
CAD LDpred1.Inf All.MultiPRS 0.148 0.191 -0.043 6.91e-11 0.147 0.190 -0.043 4.07e-10
CAD PRScs.MultiPRS All.MultiPRS 0.186 0.191 -0.005 4.64e-01 0.186 0.190 -0.004 1.57e-01
CAD LDpred2.Inf All.MultiPRS 0.162 0.191 -0.029 9.67e-06 0.157 0.190 -0.033 1.75e-08
CAD lassosum.10FCVal All.MultiPRS 0.174 0.191 -0.017 8.96e-03 0.171 0.190 -0.019 5.53e-05
CAD LDpred2.10FCVal All.MultiPRS 0.188 0.191 -0.003 6.32e-01 0.184 0.190 -0.006 2.74e-02
CAD lassosum.MultiPRS All.MultiPRS 0.187 0.191 -0.004 5.88e-01 0.186 0.190 -0.005 9.25e-02
CAD LDpred1.10FCVal All.MultiPRS 0.172 0.191 -0.019 3.97e-03 0.172 0.190 -0.018 2.08e-04
CAD All.MultiPRS All.MultiPRS 0.191 0.191 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
CAD SBayesR.PseudoVal All.MultiPRS 0.159 0.191 -0.032 1.82e-06 0.160 0.190 -0.030 4.73e-07
CAD LDpred1.MultiPRS All.MultiPRS 0.173 0.191 -0.018 9.43e-03 0.174 0.190 -0.016 6.80e-04
CAD pT+clump.MultiPRS All.MultiPRS 0.167 0.191 -0.024 5.79e-04 0.166 0.190 -0.024 4.72e-06
CAD lassosum.PseudoVal All.MultiPRS 0.162 0.191 -0.029 1.21e-05 0.160 0.190 -0.030 1.47e-07
CAD PRScs.10FCVal All.MultiPRS 0.181 0.191 -0.010 1.43e-01 0.182 0.190 -0.008 2.77e-02
CAD DBSLMM.PseudoVal All.MultiPRS 0.171 0.191 -0.020 1.85e-03 0.164 0.190 -0.026 3.17e-07
CAD SBLUP.Inf All.MultiPRS 0.162 0.191 -0.029 1.17e-05 0.157 0.190 -0.033 1.03e-08
CAD SBayesR.PseudoVal DBSLMM.PseudoVal 0.159 0.171 -0.011 2.87e-05 0.160 0.164 -0.005 3.77e-01
CAD LDpred2.Inf DBSLMM.PseudoVal 0.162 0.171 -0.009 2.55e-02 0.157 0.164 -0.007 3.76e-01
CAD pT+clump.10FCVal DBSLMM.PseudoVal 0.135 0.171 -0.036 1.19e-14 0.134 0.164 -0.030 1.35e-03
CAD PRScs.10FCVal DBSLMM.PseudoVal 0.181 0.171 0.011 5.71e-05 0.182 0.164 0.018 1.26e-03
CAD PRScs.PseudoVal DBSLMM.PseudoVal 0.181 0.171 0.011 8.13e-05 0.182 0.164 0.017 1.35e-03
CAD pT+clump.MultiPRS DBSLMM.PseudoVal 0.167 0.171 -0.003 6.39e-01 0.166 0.164 0.002 7.54e-01
CAD LDpred1.Inf DBSLMM.PseudoVal 0.148 0.171 -0.023 5.12e-08 0.147 0.164 -0.017 4.02e-02
CAD lassosum.MultiPRS DBSLMM.PseudoVal 0.187 0.171 0.017 1.53e-02 0.186 0.164 0.021 3.14e-05
CAD LDpred2.10FCVal DBSLMM.PseudoVal 0.188 0.171 0.017 2.79e-10 0.184 0.164 0.020 4.31e-04
CAD lassosum.10FCVal DBSLMM.PseudoVal 0.174 0.171 0.003 3.54e-01 0.171 0.164 0.007 3.30e-01
CAD LDpred1.10FCVal DBSLMM.PseudoVal 0.172 0.171 0.002 5.90e-01 0.172 0.164 0.008 1.74e-01
CAD LDpred1.MultiPRS DBSLMM.PseudoVal 0.173 0.171 0.003 7.09e-01 0.174 0.164 0.010 9.42e-02
CAD PRScs.MultiPRS DBSLMM.PseudoVal 0.186 0.171 0.015 2.54e-02 0.186 0.164 0.021 8.59e-06
CAD All.MultiPRS DBSLMM.PseudoVal 0.191 0.171 0.020 1.85e-03 0.190 0.164 0.026 3.17e-07
CAD LDpred2.PseudoVal DBSLMM.PseudoVal 0.107 0.171 -0.064 1.52e-36 0.111 0.164 -0.053 1.74e-07
CAD DBSLMM.PseudoVal DBSLMM.PseudoVal 0.171 0.171 0.000 1.00e+00 0.164 0.164 0.000 1.00e+00
CAD LDpred2.MultiPRS DBSLMM.PseudoVal 0.192 0.171 0.021 2.07e-03 0.186 0.164 0.021 2.95e-05
CAD lassosum.PseudoVal DBSLMM.PseudoVal 0.162 0.171 -0.008 1.18e-02 0.160 0.164 -0.004 4.99e-01
CAD SBLUP.Inf DBSLMM.PseudoVal 0.162 0.171 -0.008 2.86e-02 0.157 0.164 -0.007 3.48e-01
CAD SBayesR.PseudoVal lassosum.MultiPRS 0.159 0.187 -0.028 5.61e-05 0.160 0.186 -0.026 2.64e-05
CAD LDpred2.10FCVal lassosum.MultiPRS 0.188 0.187 0.001 9.30e-01 0.184 0.186 -0.002 5.74e-01
CAD LDpred1.10FCVal lassosum.MultiPRS 0.172 0.187 -0.015 2.75e-02 0.172 0.186 -0.013 5.21e-03
CAD LDpred2.Inf lassosum.MultiPRS 0.162 0.187 -0.025 2.32e-04 0.157 0.186 -0.028 7.52e-07
CAD PRScs.10FCVal lassosum.MultiPRS 0.181 0.187 -0.006 3.95e-01 0.182 0.186 -0.004 2.86e-01
CAD PRScs.MultiPRS lassosum.MultiPRS 0.186 0.187 -0.001 8.48e-01 0.186 0.186 0.000 9.14e-01
CAD pT+clump.MultiPRS lassosum.MultiPRS 0.167 0.187 -0.020 3.66e-03 0.166 0.186 -0.019 1.03e-04
CAD lassosum.MultiPRS lassosum.MultiPRS 0.187 0.187 0.000 1.00e+00 0.186 0.186 0.000 1.00e+00
CAD lassosum.PseudoVal lassosum.MultiPRS 0.162 0.187 -0.025 2.77e-04 0.160 0.186 -0.026 4.11e-07
CAD LDpred2.MultiPRS lassosum.MultiPRS 0.192 0.187 0.004 5.18e-01 0.186 0.186 0.000 9.41e-01
CAD LDpred1.MultiPRS lassosum.MultiPRS 0.173 0.187 -0.014 4.03e-02 0.174 0.186 -0.011 1.33e-02
CAD LDpred2.PseudoVal lassosum.MultiPRS 0.107 0.187 -0.080 4.78e-31 0.111 0.186 -0.074 1.23e-14
CAD LDpred1.Inf lassosum.MultiPRS 0.148 0.187 -0.040 1.04e-08 0.147 0.186 -0.038 1.90e-08
CAD pT+clump.10FCVal lassosum.MultiPRS 0.135 0.187 -0.053 3.25e-14 0.134 0.186 -0.052 6.58e-12
CAD lassosum.10FCVal lassosum.MultiPRS 0.174 0.187 -0.013 5.13e-02 0.171 0.186 -0.014 1.15e-04
CAD SBLUP.Inf lassosum.MultiPRS 0.162 0.187 -0.025 2.69e-04 0.157 0.186 -0.028 3.19e-07
CAD DBSLMM.PseudoVal lassosum.MultiPRS 0.171 0.187 -0.017 1.53e-02 0.164 0.186 -0.021 3.14e-05
CAD All.MultiPRS lassosum.MultiPRS 0.191 0.187 0.004 5.88e-01 0.190 0.186 0.005 9.25e-02
CAD PRScs.PseudoVal lassosum.MultiPRS 0.181 0.187 -0.006 3.65e-01 0.182 0.186 -0.004 2.61e-01
CAD LDpred1.Inf lassosum.PseudoVal 0.148 0.162 -0.015 2.07e-03 0.147 0.160 -0.013 1.79e-01
CAD PRScs.10FCVal lassosum.PseudoVal 0.181 0.162 0.019 1.52e-09 0.182 0.160 0.022 5.08e-04
CAD LDpred2.MultiPRS lassosum.PseudoVal 0.192 0.162 0.030 1.85e-05 0.186 0.160 0.026 1.26e-06
CAD lassosum.PseudoVal lassosum.PseudoVal 0.162 0.162 0.000 1.00e+00 0.160 0.160 0.000 1.00e+00
CAD PRScs.PseudoVal lassosum.PseudoVal 0.181 0.162 0.019 3.52e-09 0.182 0.160 0.022 6.59e-04
CAD DBSLMM.PseudoVal lassosum.PseudoVal 0.171 0.162 0.008 1.18e-02 0.164 0.160 0.004 4.99e-01
CAD SBLUP.Inf lassosum.PseudoVal 0.162 0.162 0.000 9.82e-01 0.157 0.160 -0.003 7.61e-01
CAD LDpred2.Inf lassosum.PseudoVal 0.162 0.162 0.000 9.36e-01 0.157 0.160 -0.002 7.91e-01
CAD pT+clump.10FCVal lassosum.PseudoVal 0.135 0.162 -0.028 3.12e-08 0.134 0.160 -0.026 1.05e-02
CAD LDpred2.10FCVal lassosum.PseudoVal 0.188 0.162 0.026 8.52e-18 0.184 0.160 0.024 6.63e-05
CAD lassosum.MultiPRS lassosum.PseudoVal 0.187 0.162 0.025 2.77e-04 0.186 0.160 0.026 4.11e-07
CAD LDpred1.10FCVal lassosum.PseudoVal 0.172 0.162 0.010 5.79e-04 0.172 0.160 0.012 3.11e-02
CAD All.MultiPRS lassosum.PseudoVal 0.191 0.162 0.029 1.21e-05 0.190 0.160 0.030 1.47e-07
CAD SBayesR.PseudoVal lassosum.PseudoVal 0.159 0.162 -0.003 3.22e-01 0.160 0.160 0.000 9.68e-01
CAD lassosum.10FCVal lassosum.PseudoVal 0.174 0.162 0.012 3.63e-04 0.171 0.160 0.012 8.26e-02
CAD pT+clump.MultiPRS lassosum.PseudoVal 0.167 0.162 0.005 4.64e-01 0.166 0.160 0.006 3.08e-01
CAD LDpred2.PseudoVal lassosum.PseudoVal 0.107 0.162 -0.055 3.35e-29 0.111 0.160 -0.049 8.73e-07
CAD LDpred1.MultiPRS lassosum.PseudoVal 0.173 0.162 0.011 1.15e-01 0.174 0.160 0.014 1.74e-02
CAD PRScs.MultiPRS lassosum.PseudoVal 0.186 0.162 0.024 5.93e-04 0.186 0.160 0.026 2.09e-05
CAD lassosum.10FCVal lassosum.10FCVal 0.174 0.174 0.000 1.00e+00 0.171 0.171 0.000 1.00e+00
CAD pT+clump.MultiPRS lassosum.10FCVal 0.167 0.174 -0.007 3.42e-01 0.166 0.171 -0.005 4.12e-01
CAD LDpred2.Inf lassosum.10FCVal 0.162 0.174 -0.012 2.75e-07 0.157 0.171 -0.014 2.97e-03
CAD SBayesR.PseudoVal lassosum.10FCVal 0.159 0.174 -0.014 4.68e-04 0.160 0.171 -0.012 1.57e-01
CAD PRScs.MultiPRS lassosum.10FCVal 0.186 0.174 0.012 8.02e-02 0.186 0.171 0.014 6.67e-04
CAD SBLUP.Inf lassosum.10FCVal 0.162 0.174 -0.012 3.21e-07 0.157 0.171 -0.014 1.92e-03
CAD lassosum.MultiPRS lassosum.10FCVal 0.187 0.174 0.013 5.13e-02 0.186 0.171 0.014 1.15e-04
CAD PRScs.10FCVal lassosum.10FCVal 0.181 0.174 0.008 3.95e-04 0.182 0.171 0.011 1.35e-02
CAD LDpred2.MultiPRS lassosum.10FCVal 0.192 0.174 0.018 9.35e-03 0.186 0.171 0.014 5.13e-04
CAD PRScs.PseudoVal lassosum.10FCVal 0.181 0.174 0.007 8.71e-04 0.182 0.171 0.010 1.80e-02
CAD LDpred2.PseudoVal lassosum.10FCVal 0.107 0.174 -0.067 5.51e-42 0.111 0.171 -0.060 1.19e-09
CAD LDpred1.MultiPRS lassosum.10FCVal 0.173 0.174 -0.001 9.14e-01 0.174 0.171 0.003 6.31e-01
CAD pT+clump.10FCVal lassosum.10FCVal 0.135 0.174 -0.039 1.13e-30 0.134 0.171 -0.037 5.16e-08
CAD All.MultiPRS lassosum.10FCVal 0.191 0.174 0.017 8.96e-03 0.190 0.171 0.019 5.53e-05
CAD LDpred1.Inf lassosum.10FCVal 0.148 0.174 -0.026 3.08e-17 0.147 0.171 -0.024 9.11e-05
CAD DBSLMM.PseudoVal lassosum.10FCVal 0.171 0.174 -0.003 3.54e-01 0.164 0.171 -0.007 3.30e-01
CAD LDpred1.10FCVal lassosum.10FCVal 0.172 0.174 -0.002 5.61e-01 0.172 0.171 0.001 8.98e-01
CAD lassosum.PseudoVal lassosum.10FCVal 0.162 0.174 -0.012 3.63e-04 0.160 0.171 -0.012 8.26e-02
CAD LDpred2.10FCVal lassosum.10FCVal 0.188 0.174 0.014 2.30e-15 0.184 0.171 0.013 3.99e-04
CAD LDpred2.10FCVal LDpred1.MultiPRS 0.188 0.173 0.015 3.17e-02 0.184 0.174 0.010 2.96e-02
CAD PRScs.PseudoVal LDpred1.MultiPRS 0.181 0.173 0.008 2.49e-01 0.182 0.174 0.008 1.06e-01
CAD LDpred2.Inf LDpred1.MultiPRS 0.162 0.173 -0.011 1.01e-01 0.157 0.174 -0.017 1.26e-02
CAD pT+clump.10FCVal LDpred1.MultiPRS 0.135 0.173 -0.039 2.70e-08 0.134 0.174 -0.040 5.74e-06
CAD SBayesR.PseudoVal LDpred1.MultiPRS 0.159 0.173 -0.014 4.90e-02 0.160 0.174 -0.014 1.98e-02
CAD All.MultiPRS LDpred1.MultiPRS 0.191 0.173 0.018 9.43e-03 0.190 0.174 0.016 6.80e-04
CAD LDpred1.10FCVal LDpred1.MultiPRS 0.172 0.173 -0.001 8.82e-01 0.172 0.174 -0.002 1.11e-01
CAD LDpred1.MultiPRS LDpred1.MultiPRS 0.173 0.173 0.000 1.00e+00 0.174 0.174 0.000 1.00e+00
CAD PRScs.10FCVal LDpred1.MultiPRS 0.181 0.173 0.008 2.27e-01 0.182 0.174 0.008 9.95e-02
CAD lassosum.PseudoVal LDpred1.MultiPRS 0.162 0.173 -0.011 1.15e-01 0.160 0.174 -0.014 1.74e-02
CAD pT+clump.MultiPRS LDpred1.MultiPRS 0.167 0.173 -0.006 4.00e-01 0.166 0.174 -0.008 2.06e-01
CAD LDpred1.Inf LDpred1.MultiPRS 0.148 0.173 -0.025 2.21e-04 0.147 0.174 -0.027 2.80e-07
CAD lassosum.MultiPRS LDpred1.MultiPRS 0.187 0.173 0.014 4.03e-02 0.186 0.174 0.011 1.33e-02
CAD PRScs.MultiPRS LDpred1.MultiPRS 0.186 0.173 0.013 6.28e-02 0.186 0.174 0.012 7.62e-03
CAD lassosum.10FCVal LDpred1.MultiPRS 0.174 0.173 0.001 9.14e-01 0.171 0.174 -0.003 6.31e-01
CAD LDpred2.PseudoVal LDpred1.MultiPRS 0.107 0.173 -0.066 1.82e-21 0.111 0.174 -0.063 1.29e-10
CAD DBSLMM.PseudoVal LDpred1.MultiPRS 0.171 0.173 -0.003 7.09e-01 0.164 0.174 -0.010 9.42e-02
CAD LDpred2.MultiPRS LDpred1.MultiPRS 0.192 0.173 0.019 6.90e-03 0.186 0.174 0.012 7.09e-03
CAD SBLUP.Inf LDpred1.MultiPRS 0.162 0.173 -0.011 1.10e-01 0.157 0.174 -0.017 9.91e-03
CAD All.MultiPRS LDpred1.Inf 0.191 0.148 0.043 6.91e-11 0.190 0.147 0.043 4.07e-10
CAD LDpred2.PseudoVal LDpred1.Inf 0.107 0.148 -0.041 4.08e-14 0.111 0.147 -0.036 8.38e-04
CAD SBayesR.PseudoVal LDpred1.Inf 0.159 0.148 0.012 1.57e-02 0.160 0.147 0.012 2.03e-01
CAD LDpred2.MultiPRS LDpred1.Inf 0.192 0.148 0.044 1.66e-10 0.186 0.147 0.039 5.35e-09
CAD PRScs.PseudoVal LDpred1.Inf 0.181 0.148 0.033 1.80e-27 0.182 0.147 0.034 1.92e-08
CAD LDpred1.Inf LDpred1.Inf 0.148 0.148 0.000 1.00e+00 0.147 0.147 0.000 1.00e+00
CAD pT+clump.10FCVal LDpred1.Inf 0.135 0.148 -0.013 9.34e-04 0.134 0.147 -0.013 1.00e-01
CAD PRScs.MultiPRS LDpred1.Inf 0.186 0.148 0.038 3.22e-08 0.186 0.147 0.039 6.28e-10
CAD lassosum.PseudoVal LDpred1.Inf 0.162 0.148 0.015 2.07e-03 0.160 0.147 0.013 1.79e-01
CAD pT+clump.MultiPRS LDpred1.Inf 0.167 0.148 0.020 4.66e-03 0.166 0.147 0.019 1.87e-02
CAD LDpred1.MultiPRS LDpred1.Inf 0.173 0.148 0.025 2.21e-04 0.174 0.147 0.027 2.80e-07
CAD PRScs.10FCVal LDpred1.Inf 0.181 0.148 0.034 7.54e-28 0.182 0.147 0.035 1.93e-08
CAD LDpred2.Inf LDpred1.Inf 0.162 0.148 0.014 2.15e-09 0.157 0.147 0.010 3.06e-02
CAD SBLUP.Inf LDpred1.Inf 0.162 0.148 0.014 7.47e-10 0.157 0.147 0.010 3.51e-02
CAD DBSLMM.PseudoVal LDpred1.Inf 0.171 0.148 0.023 5.12e-08 0.164 0.147 0.017 4.02e-02
CAD lassosum.MultiPRS LDpred1.Inf 0.187 0.148 0.040 1.04e-08 0.186 0.147 0.038 1.90e-08
CAD LDpred1.10FCVal LDpred1.Inf 0.172 0.148 0.024 8.10e-16 0.172 0.147 0.025 4.36e-05
CAD lassosum.10FCVal LDpred1.Inf 0.174 0.148 0.026 3.08e-17 0.171 0.147 0.024 9.11e-05
CAD LDpred2.10FCVal LDpred1.Inf 0.188 0.148 0.040 2.11e-40 0.184 0.147 0.037 1.03e-09
CAD LDpred1.Inf LDpred1.10FCVal 0.148 0.172 -0.024 8.10e-16 0.147 0.172 -0.025 4.36e-05
CAD PRScs.MultiPRS LDpred1.10FCVal 0.186 0.172 0.014 4.44e-02 0.186 0.172 0.014 3.32e-03
CAD LDpred1.10FCVal LDpred1.10FCVal 0.172 0.172 0.000 1.00e+00 0.172 0.172 0.000 1.00e+00
CAD All.MultiPRS LDpred1.10FCVal 0.191 0.172 0.019 3.97e-03 0.190 0.172 0.018 2.08e-04
CAD SBayesR.PseudoVal LDpred1.10FCVal 0.159 0.172 -0.013 1.80e-05 0.160 0.172 -0.013 3.25e-02
CAD DBSLMM.PseudoVal LDpred1.10FCVal 0.171 0.172 -0.002 5.90e-01 0.164 0.172 -0.008 1.74e-01
CAD pT+clump.MultiPRS LDpred1.10FCVal 0.167 0.172 -0.005 4.88e-01 0.166 0.172 -0.006 3.47e-01
CAD lassosum.MultiPRS LDpred1.10FCVal 0.187 0.172 0.015 2.75e-02 0.186 0.172 0.013 5.21e-03
CAD PRScs.10FCVal LDpred1.10FCVal 0.181 0.172 0.009 2.25e-04 0.182 0.172 0.010 5.38e-02
CAD lassosum.10FCVal LDpred1.10FCVal 0.174 0.172 0.002 5.61e-01 0.171 0.172 -0.001 8.98e-01
CAD SBLUP.Inf LDpred1.10FCVal 0.162 0.172 -0.010 5.47e-03 0.157 0.172 -0.015 3.80e-02
CAD LDpred2.PseudoVal LDpred1.10FCVal 0.107 0.172 -0.065 8.88e-39 0.111 0.172 -0.061 1.00e-09
CAD pT+clump.10FCVal LDpred1.10FCVal 0.135 0.172 -0.038 9.68e-17 0.134 0.172 -0.038 3.33e-05
CAD LDpred2.MultiPRS LDpred1.10FCVal 0.192 0.172 0.020 4.30e-03 0.186 0.172 0.014 2.40e-03
CAD PRScs.PseudoVal LDpred1.10FCVal 0.181 0.172 0.009 3.27e-04 0.182 0.172 0.009 5.67e-02
CAD LDpred2.10FCVal LDpred1.10FCVal 0.188 0.172 0.016 6.63e-11 0.184 0.172 0.012 1.51e-02
CAD LDpred1.MultiPRS LDpred1.10FCVal 0.173 0.172 0.001 8.82e-01 0.174 0.172 0.002 1.11e-01
CAD LDpred2.Inf LDpred1.10FCVal 0.162 0.172 -0.010 4.84e-03 0.157 0.172 -0.015 4.51e-02
CAD lassosum.PseudoVal LDpred1.10FCVal 0.162 0.172 -0.010 5.79e-04 0.160 0.172 -0.012 3.11e-02
CAD LDpred1.Inf LDpred2.MultiPRS 0.148 0.192 -0.044 1.66e-10 0.147 0.186 -0.039 5.35e-09
CAD DBSLMM.PseudoVal LDpred2.MultiPRS 0.171 0.192 -0.021 2.07e-03 0.164 0.186 -0.021 2.95e-05
CAD SBLUP.Inf LDpred2.MultiPRS 0.162 0.192 -0.030 1.72e-05 0.157 0.186 -0.029 7.35e-08
CAD LDpred2.Inf LDpred2.MultiPRS 0.162 0.192 -0.030 1.43e-05 0.157 0.186 -0.028 1.04e-07
CAD pT+clump.10FCVal LDpred2.MultiPRS 0.135 0.192 -0.057 1.59e-16 0.134 0.186 -0.052 4.26e-11
CAD LDpred2.10FCVal LDpred2.MultiPRS 0.188 0.192 -0.004 5.75e-01 0.184 0.186 -0.002 2.79e-01
CAD PRScs.PseudoVal LDpred2.MultiPRS 0.181 0.192 -0.011 1.20e-01 0.182 0.186 -0.004 2.07e-01
CAD LDpred1.10FCVal LDpred2.MultiPRS 0.172 0.192 -0.020 4.30e-03 0.172 0.186 -0.014 2.40e-03
CAD All.MultiPRS LDpred2.MultiPRS 0.191 0.192 -0.001 9.15e-01 0.190 0.186 0.004 3.49e-02
CAD SBayesR.PseudoVal LDpred2.MultiPRS 0.159 0.192 -0.032 2.97e-06 0.160 0.186 -0.026 2.31e-05
CAD lassosum.10FCVal LDpred2.MultiPRS 0.174 0.192 -0.018 9.35e-03 0.171 0.186 -0.014 5.13e-04
CAD pT+clump.MultiPRS LDpred2.MultiPRS 0.167 0.192 -0.024 3.88e-04 0.166 0.186 -0.020 2.15e-04
CAD lassosum.MultiPRS LDpred2.MultiPRS 0.187 0.192 -0.004 5.18e-01 0.186 0.186 0.000 9.41e-01
CAD PRScs.10FCVal LDpred2.MultiPRS 0.181 0.192 -0.010 1.34e-01 0.182 0.186 -0.004 2.37e-01
CAD PRScs.MultiPRS LDpred2.MultiPRS 0.186 0.192 -0.006 4.02e-01 0.186 0.186 0.000 9.78e-01
CAD lassosum.PseudoVal LDpred2.MultiPRS 0.162 0.192 -0.030 1.85e-05 0.160 0.186 -0.026 1.26e-06
CAD LDpred2.PseudoVal LDpred2.MultiPRS 0.107 0.192 -0.085 2.86e-34 0.111 0.186 -0.075 6.43e-16
CAD LDpred1.MultiPRS LDpred2.MultiPRS 0.173 0.192 -0.019 6.90e-03 0.174 0.186 -0.012 7.09e-03
CAD LDpred2.MultiPRS LDpred2.MultiPRS 0.192 0.192 0.000 1.00e+00 0.186 0.186 0.000 1.00e+00
CAD LDpred1.Inf LDpred2.10FCVal 0.148 0.188 -0.040 2.11e-40 0.147 0.184 -0.037 1.03e-09
CAD PRScs.MultiPRS LDpred2.10FCVal 0.186 0.188 -0.002 7.80e-01 0.186 0.184 0.002 4.80e-01
CAD LDpred2.MultiPRS LDpred2.10FCVal 0.192 0.188 0.004 5.75e-01 0.186 0.184 0.002 2.79e-01
CAD PRScs.PseudoVal LDpred2.10FCVal 0.181 0.188 -0.007 5.17e-06 0.182 0.184 -0.002 4.55e-01
CAD LDpred2.10FCVal LDpred2.10FCVal 0.188 0.188 0.000 1.00e+00 0.184 0.184 0.000 1.00e+00
CAD lassosum.MultiPRS LDpred2.10FCVal 0.187 0.188 -0.001 9.30e-01 0.186 0.184 0.002 5.74e-01
CAD LDpred1.10FCVal LDpred2.10FCVal 0.172 0.188 -0.016 6.63e-11 0.172 0.184 -0.012 1.51e-02
CAD All.MultiPRS LDpred2.10FCVal 0.191 0.188 0.003 6.32e-01 0.190 0.184 0.006 2.74e-02
CAD SBayesR.PseudoVal LDpred2.10FCVal 0.159 0.188 -0.028 7.04e-17 0.160 0.184 -0.024 4.16e-04
CAD DBSLMM.PseudoVal LDpred2.10FCVal 0.171 0.188 -0.017 2.79e-10 0.164 0.184 -0.020 4.31e-04
CAD pT+clump.MultiPRS LDpred2.10FCVal 0.167 0.188 -0.021 2.88e-03 0.166 0.184 -0.018 1.04e-03
CAD lassosum.PseudoVal LDpred2.10FCVal 0.162 0.188 -0.026 8.52e-18 0.160 0.184 -0.024 6.63e-05
CAD PRScs.10FCVal LDpred2.10FCVal 0.181 0.188 -0.006 2.02e-05 0.182 0.184 -0.002 5.10e-01
CAD lassosum.10FCVal LDpred2.10FCVal 0.174 0.188 -0.014 2.30e-15 0.171 0.184 -0.013 3.99e-04
CAD SBLUP.Inf LDpred2.10FCVal 0.162 0.188 -0.026 2.86e-31 0.157 0.184 -0.027 1.60e-09
CAD LDpred2.PseudoVal LDpred2.10FCVal 0.107 0.188 -0.081 1.17e-77 0.111 0.184 -0.073 1.06e-16
CAD pT+clump.10FCVal LDpred2.10FCVal 0.135 0.188 -0.053 2.35e-49 0.134 0.184 -0.050 9.99e-12
CAD LDpred2.Inf LDpred2.10FCVal 0.162 0.188 -0.026 8.86e-33 0.157 0.184 -0.026 1.70e-09
CAD LDpred1.MultiPRS LDpred2.10FCVal 0.173 0.188 -0.015 3.17e-02 0.174 0.184 -0.010 2.96e-02
CAD lassosum.10FCVal LDpred2.PseudoVal 0.174 0.107 0.067 5.51e-42 0.171 0.111 0.060 1.19e-09
CAD SBLUP.Inf LDpred2.PseudoVal 0.162 0.107 0.055 1.36e-25 0.157 0.111 0.046 1.53e-05
CAD SBayesR.PseudoVal LDpred2.PseudoVal 0.159 0.107 0.053 1.47e-25 0.160 0.111 0.049 1.54e-06
CAD All.MultiPRS LDpred2.PseudoVal 0.191 0.107 0.084 8.32e-36 0.190 0.111 0.079 5.04e-17
CAD PRScs.PseudoVal LDpred2.PseudoVal 0.181 0.107 0.074 5.44e-54 0.182 0.111 0.071 2.35e-13
CAD lassosum.MultiPRS LDpred2.PseudoVal 0.187 0.107 0.080 4.78e-31 0.186 0.111 0.074 1.23e-14
CAD PRScs.MultiPRS LDpred2.PseudoVal 0.186 0.107 0.079 1.42e-29 0.186 0.111 0.075 2.50e-14
CAD LDpred2.MultiPRS LDpred2.PseudoVal 0.192 0.107 0.085 2.86e-34 0.186 0.111 0.075 6.43e-16
CAD PRScs.10FCVal LDpred2.PseudoVal 0.181 0.107 0.075 2.12e-54 0.182 0.111 0.071 2.02e-13
CAD LDpred2.PseudoVal LDpred2.PseudoVal 0.107 0.107 0.000 1.00e+00 0.111 0.111 0.000 1.00e+00
CAD pT+clump.MultiPRS LDpred2.PseudoVal 0.167 0.107 0.060 5.92e-18 0.166 0.111 0.055 1.63e-08
CAD pT+clump.10FCVal LDpred2.PseudoVal 0.135 0.107 0.028 5.25e-07 0.134 0.111 0.023 3.98e-02
CAD lassosum.PseudoVal LDpred2.PseudoVal 0.162 0.107 0.055 3.35e-29 0.160 0.111 0.049 8.73e-07
CAD LDpred1.Inf LDpred2.PseudoVal 0.148 0.107 0.041 4.08e-14 0.147 0.111 0.036 8.38e-04
CAD LDpred1.MultiPRS LDpred2.PseudoVal 0.173 0.107 0.066 1.82e-21 0.174 0.111 0.063 1.29e-10
CAD LDpred1.10FCVal LDpred2.PseudoVal 0.172 0.107 0.065 8.88e-39 0.172 0.111 0.061 1.00e-09
CAD LDpred2.Inf LDpred2.PseudoVal 0.162 0.107 0.055 6.72e-26 0.157 0.111 0.046 1.08e-05
CAD LDpred2.10FCVal LDpred2.PseudoVal 0.188 0.107 0.081 1.17e-77 0.184 0.111 0.073 1.06e-16
CAD DBSLMM.PseudoVal LDpred2.PseudoVal 0.171 0.107 0.064 1.52e-36 0.164 0.111 0.053 1.74e-07
CAD pT+clump.MultiPRS LDpred2.Inf 0.167 0.162 0.005 4.31e-01 0.166 0.157 0.009 2.36e-01
CAD lassosum.MultiPRS LDpred2.Inf 0.187 0.162 0.025 2.32e-04 0.186 0.157 0.028 7.52e-07
CAD SBayesR.PseudoVal LDpred2.Inf 0.159 0.162 -0.002 6.33e-01 0.160 0.157 0.002 8.20e-01
CAD All.MultiPRS LDpred2.Inf 0.191 0.162 0.029 9.67e-06 0.190 0.157 0.033 1.75e-08
CAD SBLUP.Inf LDpred2.Inf 0.162 0.162 0.000 5.79e-01 0.157 0.157 0.000 7.37e-01
CAD LDpred2.PseudoVal LDpred2.Inf 0.107 0.162 -0.055 6.72e-26 0.111 0.157 -0.046 1.08e-05
CAD PRScs.MultiPRS LDpred2.Inf 0.186 0.162 0.024 4.86e-04 0.186 0.157 0.028 1.18e-08
CAD LDpred2.MultiPRS LDpred2.Inf 0.192 0.162 0.030 1.43e-05 0.186 0.157 0.028 1.04e-07
CAD PRScs.10FCVal LDpred2.Inf 0.181 0.162 0.020 3.52e-16 0.182 0.157 0.025 5.18e-07
CAD LDpred1.Inf LDpred2.Inf 0.148 0.162 -0.014 2.15e-09 0.147 0.157 -0.010 3.06e-02
CAD LDpred1.MultiPRS LDpred2.Inf 0.173 0.162 0.011 1.01e-01 0.174 0.157 0.017 1.26e-02
CAD pT+clump.10FCVal LDpred2.Inf 0.135 0.162 -0.027 2.87e-16 0.134 0.157 -0.023 5.01e-04
CAD lassosum.PseudoVal LDpred2.Inf 0.162 0.162 0.000 9.36e-01 0.160 0.157 0.002 7.91e-01
CAD PRScs.PseudoVal LDpred2.Inf 0.181 0.162 0.019 2.46e-15 0.182 0.157 0.024 7.55e-07
CAD DBSLMM.PseudoVal LDpred2.Inf 0.171 0.162 0.009 2.55e-02 0.164 0.157 0.007 3.76e-01
CAD LDpred1.10FCVal LDpred2.Inf 0.172 0.162 0.010 4.84e-03 0.172 0.157 0.015 4.51e-02
CAD LDpred2.Inf LDpred2.Inf 0.162 0.162 0.000 1.00e+00 0.157 0.157 0.000 1.00e+00
CAD lassosum.10FCVal LDpred2.Inf 0.174 0.162 0.012 2.75e-07 0.171 0.157 0.014 2.97e-03
CAD LDpred2.10FCVal LDpred2.Inf 0.188 0.162 0.026 8.86e-33 0.184 0.157 0.026 1.70e-09
CAD PRScs.10FCVal PRScs.MultiPRS 0.181 0.186 -0.005 5.12e-01 0.182 0.186 -0.004 6.57e-02
CAD LDpred1.10FCVal PRScs.MultiPRS 0.172 0.186 -0.014 4.44e-02 0.172 0.186 -0.014 3.32e-03
CAD lassosum.MultiPRS PRScs.MultiPRS 0.187 0.186 0.001 8.48e-01 0.186 0.186 0.000 9.14e-01
CAD LDpred2.MultiPRS PRScs.MultiPRS 0.192 0.186 0.006 4.02e-01 0.186 0.186 0.000 9.78e-01
CAD All.MultiPRS PRScs.MultiPRS 0.191 0.186 0.005 4.64e-01 0.190 0.186 0.004 1.57e-01
CAD PRScs.PseudoVal PRScs.MultiPRS 0.181 0.186 -0.005 4.76e-01 0.182 0.186 -0.004 6.60e-02
CAD LDpred1.MultiPRS PRScs.MultiPRS 0.173 0.186 -0.013 6.28e-02 0.174 0.186 -0.012 7.62e-03
CAD pT+clump.MultiPRS PRScs.MultiPRS 0.167 0.186 -0.019 6.89e-03 0.166 0.186 -0.020 1.85e-04
CAD lassosum.PseudoVal PRScs.MultiPRS 0.162 0.186 -0.024 5.93e-04 0.160 0.186 -0.026 2.09e-05
CAD SBayesR.PseudoVal PRScs.MultiPRS 0.159 0.186 -0.026 1.28e-04 0.160 0.186 -0.026 6.63e-05
CAD DBSLMM.PseudoVal PRScs.MultiPRS 0.171 0.186 -0.015 2.54e-02 0.164 0.186 -0.021 8.59e-06
CAD SBLUP.Inf PRScs.MultiPRS 0.162 0.186 -0.024 5.64e-04 0.157 0.186 -0.029 3.18e-09
CAD LDpred2.Inf PRScs.MultiPRS 0.162 0.186 -0.024 4.86e-04 0.157 0.186 -0.028 1.18e-08
CAD pT+clump.10FCVal PRScs.MultiPRS 0.135 0.186 -0.051 1.35e-13 0.134 0.186 -0.052 3.08e-12
CAD LDpred2.10FCVal PRScs.MultiPRS 0.188 0.186 0.002 7.80e-01 0.184 0.186 -0.002 4.80e-01
CAD lassosum.10FCVal PRScs.MultiPRS 0.174 0.186 -0.012 8.02e-02 0.171 0.186 -0.014 6.67e-04
CAD LDpred2.PseudoVal PRScs.MultiPRS 0.107 0.186 -0.079 1.42e-29 0.111 0.186 -0.075 2.50e-14
CAD LDpred1.Inf PRScs.MultiPRS 0.148 0.186 -0.038 3.22e-08 0.147 0.186 -0.039 6.28e-10
CAD PRScs.MultiPRS PRScs.MultiPRS 0.186 0.186 0.000 1.00e+00 0.186 0.186 0.000 1.00e+00
CAD LDpred2.PseudoVal PRScs.10FCVal 0.107 0.181 -0.075 2.12e-54 0.111 0.182 -0.071 2.02e-13
CAD PRScs.10FCVal PRScs.10FCVal 0.181 0.181 0.000 1.00e+00 0.182 0.182 0.000 1.00e+00
CAD LDpred2.MultiPRS PRScs.10FCVal 0.192 0.181 0.010 1.34e-01 0.186 0.182 0.004 2.37e-01
CAD pT+clump.MultiPRS PRScs.10FCVal 0.167 0.181 -0.014 4.05e-02 0.166 0.182 -0.016 6.35e-03
CAD LDpred1.Inf PRScs.10FCVal 0.148 0.181 -0.034 7.54e-28 0.147 0.182 -0.035 1.93e-08
CAD LDpred1.MultiPRS PRScs.10FCVal 0.173 0.181 -0.008 2.27e-01 0.174 0.182 -0.008 9.95e-02
CAD pT+clump.10FCVal PRScs.10FCVal 0.135 0.181 -0.047 7.26e-36 0.134 0.182 -0.048 3.75e-10
CAD lassosum.PseudoVal PRScs.10FCVal 0.162 0.181 -0.019 1.52e-09 0.160 0.182 -0.022 5.08e-04
CAD PRScs.PseudoVal PRScs.10FCVal 0.181 0.181 0.000 8.06e-01 0.182 0.182 0.000 9.32e-01
CAD DBSLMM.PseudoVal PRScs.10FCVal 0.171 0.181 -0.011 5.71e-05 0.164 0.182 -0.018 1.26e-03
CAD SBLUP.Inf PRScs.10FCVal 0.162 0.181 -0.019 1.82e-16 0.157 0.182 -0.025 1.91e-07
CAD LDpred2.Inf PRScs.10FCVal 0.162 0.181 -0.020 3.52e-16 0.157 0.182 -0.025 5.18e-07
CAD lassosum.10FCVal PRScs.10FCVal 0.174 0.181 -0.008 3.95e-04 0.171 0.182 -0.011 1.35e-02
CAD LDpred2.10FCVal PRScs.10FCVal 0.188 0.181 0.006 2.02e-05 0.184 0.182 0.002 5.10e-01
CAD lassosum.MultiPRS PRScs.10FCVal 0.187 0.181 0.006 3.95e-01 0.186 0.182 0.004 2.86e-01
CAD LDpred1.10FCVal PRScs.10FCVal 0.172 0.181 -0.009 2.25e-04 0.172 0.182 -0.010 5.38e-02
CAD All.MultiPRS PRScs.10FCVal 0.191 0.181 0.010 1.43e-01 0.190 0.182 0.008 2.77e-02
CAD SBayesR.PseudoVal PRScs.10FCVal 0.159 0.181 -0.022 2.00e-10 0.160 0.182 -0.022 1.29e-03
CAD PRScs.MultiPRS PRScs.10FCVal 0.186 0.181 0.005 5.12e-01 0.186 0.182 0.004 6.57e-02
CAD All.MultiPRS PRScs.PseudoVal 0.191 0.181 0.010 1.28e-01 0.190 0.182 0.008 2.50e-02
CAD pT+clump.MultiPRS PRScs.PseudoVal 0.167 0.181 -0.014 4.66e-02 0.166 0.182 -0.015 6.98e-03
CAD LDpred2.PseudoVal PRScs.PseudoVal 0.107 0.181 -0.074 5.44e-54 0.111 0.182 -0.071 2.35e-13
CAD SBayesR.PseudoVal PRScs.PseudoVal 0.159 0.181 -0.022 4.15e-10 0.160 0.182 -0.022 1.52e-03
CAD LDpred2.MultiPRS PRScs.PseudoVal 0.192 0.181 0.011 1.20e-01 0.186 0.182 0.004 2.07e-01
CAD SBLUP.Inf PRScs.PseudoVal 0.162 0.181 -0.019 1.44e-15 0.157 0.182 -0.025 2.83e-07
CAD LDpred1.Inf PRScs.PseudoVal 0.148 0.181 -0.033 1.80e-27 0.147 0.182 -0.034 1.92e-08
CAD PRScs.10FCVal PRScs.PseudoVal 0.181 0.181 0.000 8.06e-01 0.182 0.182 0.000 9.32e-01
CAD LDpred2.Inf PRScs.PseudoVal 0.162 0.181 -0.019 2.46e-15 0.157 0.182 -0.024 7.55e-07
CAD PRScs.PseudoVal PRScs.PseudoVal 0.181 0.181 0.000 1.00e+00 0.182 0.182 0.000 1.00e+00
CAD LDpred2.10FCVal PRScs.PseudoVal 0.188 0.181 0.007 5.17e-06 0.184 0.182 0.002 4.55e-01
CAD pT+clump.10FCVal PRScs.PseudoVal 0.135 0.181 -0.046 3.89e-35 0.134 0.182 -0.048 4.87e-10
CAD PRScs.MultiPRS PRScs.PseudoVal 0.186 0.181 0.005 4.76e-01 0.186 0.182 0.004 6.60e-02
CAD lassosum.PseudoVal PRScs.PseudoVal 0.162 0.181 -0.019 3.52e-09 0.160 0.182 -0.022 6.59e-04
CAD lassosum.10FCVal PRScs.PseudoVal 0.174 0.181 -0.007 8.71e-04 0.171 0.182 -0.010 1.80e-02
CAD LDpred1.MultiPRS PRScs.PseudoVal 0.173 0.181 -0.008 2.49e-01 0.174 0.182 -0.008 1.06e-01
CAD lassosum.MultiPRS PRScs.PseudoVal 0.187 0.181 0.006 3.65e-01 0.186 0.182 0.004 2.61e-01
CAD LDpred1.10FCVal PRScs.PseudoVal 0.172 0.181 -0.009 3.27e-04 0.172 0.182 -0.009 5.67e-02
CAD DBSLMM.PseudoVal PRScs.PseudoVal 0.171 0.181 -0.011 8.13e-05 0.164 0.182 -0.017 1.35e-03
CAD All.MultiPRS pT+clump.MultiPRS 0.191 0.167 0.024 5.79e-04 0.190 0.166 0.024 4.72e-06
CAD SBayesR.PseudoVal pT+clump.MultiPRS 0.159 0.167 -0.008 2.62e-01 0.160 0.166 -0.007 3.42e-01
CAD LDpred1.MultiPRS pT+clump.MultiPRS 0.173 0.167 0.006 4.00e-01 0.174 0.166 0.008 2.06e-01
CAD pT+clump.MultiPRS pT+clump.MultiPRS 0.167 0.167 0.000 1.00e+00 0.166 0.166 0.000 1.00e+00
CAD lassosum.PseudoVal pT+clump.MultiPRS 0.162 0.167 -0.005 4.64e-01 0.160 0.166 -0.006 3.08e-01
CAD PRScs.10FCVal pT+clump.MultiPRS 0.181 0.167 0.014 4.05e-02 0.182 0.166 0.016 6.35e-03
CAD DBSLMM.PseudoVal pT+clump.MultiPRS 0.171 0.167 0.003 6.39e-01 0.164 0.166 -0.002 7.54e-01
CAD SBLUP.Inf pT+clump.MultiPRS 0.162 0.167 -0.005 4.54e-01 0.157 0.166 -0.009 2.10e-01
CAD LDpred2.Inf pT+clump.MultiPRS 0.162 0.167 -0.005 4.31e-01 0.157 0.166 -0.009 2.36e-01
CAD pT+clump.10FCVal pT+clump.MultiPRS 0.135 0.167 -0.033 2.49e-06 0.134 0.166 -0.032 2.00e-07
CAD LDpred2.10FCVal pT+clump.MultiPRS 0.188 0.167 0.021 2.88e-03 0.184 0.166 0.018 1.04e-03
CAD PRScs.PseudoVal pT+clump.MultiPRS 0.181 0.167 0.014 4.66e-02 0.182 0.166 0.015 6.98e-03
CAD LDpred1.10FCVal pT+clump.MultiPRS 0.172 0.167 0.005 4.88e-01 0.172 0.166 0.006 3.47e-01
CAD LDpred1.Inf pT+clump.MultiPRS 0.148 0.167 -0.020 4.66e-03 0.147 0.166 -0.019 1.87e-02
CAD PRScs.MultiPRS pT+clump.MultiPRS 0.186 0.167 0.019 6.89e-03 0.186 0.166 0.020 1.85e-04
CAD lassosum.10FCVal pT+clump.MultiPRS 0.174 0.167 0.007 3.42e-01 0.171 0.166 0.005 4.12e-01
CAD LDpred2.PseudoVal pT+clump.MultiPRS 0.107 0.167 -0.060 5.92e-18 0.111 0.166 -0.055 1.63e-08
CAD lassosum.MultiPRS pT+clump.MultiPRS 0.187 0.167 0.020 3.66e-03 0.186 0.166 0.019 1.03e-04
CAD LDpred2.MultiPRS pT+clump.MultiPRS 0.192 0.167 0.024 3.88e-04 0.186 0.166 0.020 2.15e-04
CAD LDpred2.10FCVal pT+clump.10FCVal 0.188 0.135 0.053 2.35e-49 0.184 0.134 0.050 9.99e-12
CAD pT+clump.MultiPRS pT+clump.10FCVal 0.167 0.135 0.033 2.49e-06 0.166 0.134 0.032 2.00e-07
CAD LDpred2.Inf pT+clump.10FCVal 0.162 0.135 0.027 2.87e-16 0.157 0.134 0.023 5.01e-04
CAD SBayesR.PseudoVal pT+clump.10FCVal 0.159 0.135 0.025 3.38e-06 0.160 0.134 0.026 1.85e-02
CAD PRScs.MultiPRS pT+clump.10FCVal 0.186 0.135 0.051 1.35e-13 0.186 0.134 0.052 3.08e-12
CAD SBLUP.Inf pT+clump.10FCVal 0.162 0.135 0.028 3.67e-17 0.157 0.134 0.023 4.60e-04
CAD lassosum.MultiPRS pT+clump.10FCVal 0.187 0.135 0.053 3.25e-14 0.186 0.134 0.052 6.58e-12
CAD PRScs.10FCVal pT+clump.10FCVal 0.181 0.135 0.047 7.26e-36 0.182 0.134 0.048 3.75e-10
CAD LDpred2.MultiPRS pT+clump.10FCVal 0.192 0.135 0.057 1.59e-16 0.186 0.134 0.052 4.26e-11
CAD lassosum.10FCVal pT+clump.10FCVal 0.174 0.135 0.039 1.13e-30 0.171 0.134 0.037 5.16e-08
CAD LDpred2.PseudoVal pT+clump.10FCVal 0.107 0.135 -0.028 5.25e-07 0.111 0.134 -0.023 3.98e-02
CAD LDpred1.MultiPRS pT+clump.10FCVal 0.173 0.135 0.039 2.70e-08 0.174 0.134 0.040 5.74e-06
CAD pT+clump.10FCVal pT+clump.10FCVal 0.135 0.135 0.000 1.00e+00 0.134 0.134 0.000 1.00e+00
CAD All.MultiPRS pT+clump.10FCVal 0.191 0.135 0.056 2.96e-17 0.190 0.134 0.056 7.05e-13
CAD LDpred1.Inf pT+clump.10FCVal 0.148 0.135 0.013 9.34e-04 0.147 0.134 0.013 1.00e-01
CAD DBSLMM.PseudoVal pT+clump.10FCVal 0.171 0.135 0.036 1.19e-14 0.164 0.134 0.030 1.35e-03
CAD LDpred1.10FCVal pT+clump.10FCVal 0.172 0.135 0.038 9.68e-17 0.172 0.134 0.038 3.33e-05
CAD lassosum.PseudoVal pT+clump.10FCVal 0.162 0.135 0.028 3.12e-08 0.160 0.134 0.026 1.05e-02
CAD PRScs.PseudoVal pT+clump.10FCVal 0.181 0.135 0.046 3.89e-35 0.182 0.134 0.048 4.87e-10
CAD pT+clump.MultiPRS SBayesR.PseudoVal 0.167 0.159 0.008 2.62e-01 0.166 0.160 0.007 3.42e-01
CAD LDpred1.10FCVal SBayesR.PseudoVal 0.172 0.159 0.013 1.80e-05 0.172 0.160 0.013 3.25e-02
CAD PRScs.10FCVal SBayesR.PseudoVal 0.181 0.159 0.022 2.00e-10 0.182 0.160 0.022 1.29e-03
CAD LDpred2.10FCVal SBayesR.PseudoVal 0.188 0.159 0.028 7.04e-17 0.184 0.160 0.024 4.16e-04
CAD lassosum.10FCVal SBayesR.PseudoVal 0.174 0.159 0.014 4.68e-04 0.171 0.160 0.012 1.57e-01
CAD LDpred2.PseudoVal SBayesR.PseudoVal 0.107 0.159 -0.053 1.47e-25 0.111 0.160 -0.049 1.54e-06
CAD lassosum.MultiPRS SBayesR.PseudoVal 0.187 0.159 0.028 5.61e-05 0.186 0.160 0.026 2.64e-05
CAD LDpred2.MultiPRS SBayesR.PseudoVal 0.192 0.159 0.032 2.97e-06 0.186 0.160 0.026 2.31e-05
CAD All.MultiPRS SBayesR.PseudoVal 0.191 0.159 0.032 1.82e-06 0.190 0.160 0.030 4.73e-07
CAD PRScs.PseudoVal SBayesR.PseudoVal 0.181 0.159 0.022 4.15e-10 0.182 0.160 0.022 1.52e-03
CAD LDpred1.MultiPRS SBayesR.PseudoVal 0.173 0.159 0.014 4.90e-02 0.174 0.160 0.014 1.98e-02
CAD pT+clump.10FCVal SBayesR.PseudoVal 0.135 0.159 -0.025 3.38e-06 0.134 0.160 -0.026 1.85e-02
CAD lassosum.PseudoVal SBayesR.PseudoVal 0.162 0.159 0.003 3.22e-01 0.160 0.160 0.000 9.68e-01
CAD SBayesR.PseudoVal SBayesR.PseudoVal 0.159 0.159 0.000 1.00e+00 0.160 0.160 0.000 1.00e+00
CAD DBSLMM.PseudoVal SBayesR.PseudoVal 0.171 0.159 0.011 2.87e-05 0.164 0.160 0.005 3.77e-01
CAD SBLUP.Inf SBayesR.PseudoVal 0.162 0.159 0.003 5.91e-01 0.157 0.160 -0.003 7.92e-01
CAD LDpred2.Inf SBayesR.PseudoVal 0.162 0.159 0.002 6.33e-01 0.157 0.160 -0.002 8.20e-01
CAD LDpred1.Inf SBayesR.PseudoVal 0.148 0.159 -0.012 1.57e-02 0.147 0.160 -0.012 2.03e-01
CAD PRScs.MultiPRS SBayesR.PseudoVal 0.186 0.159 0.026 1.28e-04 0.186 0.160 0.026 6.63e-05
CAD LDpred2.10FCVal SBLUP.Inf 0.188 0.162 0.026 2.86e-31 0.184 0.157 0.027 1.60e-09
CAD PRScs.PseudoVal SBLUP.Inf 0.181 0.162 0.019 1.44e-15 0.182 0.157 0.025 2.83e-07
CAD LDpred1.10FCVal SBLUP.Inf 0.172 0.162 0.010 5.47e-03 0.172 0.157 0.015 3.80e-02
CAD LDpred2.Inf SBLUP.Inf 0.162 0.162 0.000 5.79e-01 0.157 0.157 0.000 7.37e-01
CAD SBayesR.PseudoVal SBLUP.Inf 0.159 0.162 -0.003 5.91e-01 0.160 0.157 0.003 7.92e-01
CAD lassosum.10FCVal SBLUP.Inf 0.174 0.162 0.012 3.21e-07 0.171 0.157 0.014 1.92e-03
CAD pT+clump.MultiPRS SBLUP.Inf 0.167 0.162 0.005 4.54e-01 0.166 0.157 0.009 2.10e-01
CAD lassosum.MultiPRS SBLUP.Inf 0.187 0.162 0.025 2.69e-04 0.186 0.157 0.028 3.19e-07
CAD PRScs.10FCVal SBLUP.Inf 0.181 0.162 0.019 1.82e-16 0.182 0.157 0.025 1.91e-07
CAD PRScs.MultiPRS SBLUP.Inf 0.186 0.162 0.024 5.64e-04 0.186 0.157 0.029 3.18e-09
CAD LDpred1.MultiPRS SBLUP.Inf 0.173 0.162 0.011 1.10e-01 0.174 0.157 0.017 9.91e-03
CAD LDpred2.PseudoVal SBLUP.Inf 0.107 0.162 -0.055 1.36e-25 0.111 0.157 -0.046 1.53e-05
CAD LDpred1.Inf SBLUP.Inf 0.148 0.162 -0.014 7.47e-10 0.147 0.157 -0.010 3.51e-02
CAD LDpred2.MultiPRS SBLUP.Inf 0.192 0.162 0.030 1.72e-05 0.186 0.157 0.029 7.35e-08
CAD All.MultiPRS SBLUP.Inf 0.191 0.162 0.029 1.17e-05 0.190 0.157 0.033 1.03e-08
CAD SBLUP.Inf SBLUP.Inf 0.162 0.162 0.000 1.00e+00 0.157 0.157 0.000 1.00e+00
CAD DBSLMM.PseudoVal SBLUP.Inf 0.171 0.162 0.008 2.86e-02 0.164 0.157 0.007 3.48e-01
CAD pT+clump.10FCVal SBLUP.Inf 0.135 0.162 -0.028 3.67e-17 0.134 0.157 -0.023 4.60e-04
CAD lassosum.PseudoVal SBLUP.Inf 0.162 0.162 0.000 9.82e-01 0.160 0.157 0.003 7.61e-01
IBD LDpred2.PseudoVal All.MultiPRS 0.100 0.146 -0.046 6.78e-11 0.103 0.151 -0.048 3.06e-10
IBD pT+clump.10FCVal All.MultiPRS 0.112 0.146 -0.034 1.23e-06 0.112 0.151 -0.038 1.18e-08
IBD LDpred2.MultiPRS All.MultiPRS 0.143 0.146 -0.003 4.68e-03 0.148 0.151 -0.003 1.30e-01
IBD PRScs.PseudoVal All.MultiPRS 0.130 0.146 -0.016 2.37e-02 0.128 0.151 -0.023 8.64e-07
IBD LDpred1.Inf All.MultiPRS 0.100 0.146 -0.045 9.52e-11 0.104 0.151 -0.046 2.48e-09
IBD PRScs.MultiPRS All.MultiPRS 0.135 0.146 -0.010 1.64e-08 0.137 0.151 -0.013 2.70e-04
IBD LDpred2.Inf All.MultiPRS 0.096 0.146 -0.050 1.80e-12 0.099 0.151 -0.052 8.38e-11
IBD lassosum.10FCVal All.MultiPRS 0.134 0.146 -0.011 1.08e-01 0.136 0.151 -0.015 3.09e-04
IBD LDpred2.10FCVal All.MultiPRS 0.143 0.146 -0.003 7.13e-01 0.145 0.151 -0.005 2.18e-02
IBD lassosum.MultiPRS All.MultiPRS 0.142 0.146 -0.003 5.78e-03 0.146 0.151 -0.005 2.40e-02
IBD LDpred1.10FCVal All.MultiPRS 0.130 0.146 -0.016 2.46e-02 0.134 0.151 -0.016 5.90e-04
IBD All.MultiPRS All.MultiPRS 0.146 0.146 0.000 1.00e+00 0.151 0.151 0.000 1.00e+00
IBD SBayesR.PseudoVal All.MultiPRS 0.122 0.146 -0.023 8.33e-04 0.130 0.151 -0.021 1.68e-04
IBD LDpred1.MultiPRS All.MultiPRS 0.131 0.146 -0.014 3.85e-10 0.137 0.151 -0.013 2.45e-03
IBD pT+clump.MultiPRS All.MultiPRS 0.128 0.146 -0.018 1.20e-02 0.137 0.151 -0.014 4.39e-03
IBD lassosum.PseudoVal All.MultiPRS 0.134 0.146 -0.012 9.17e-02 0.137 0.151 -0.014 6.95e-04
IBD PRScs.10FCVal All.MultiPRS 0.129 0.146 -0.017 1.65e-02 0.133 0.151 -0.018 1.04e-04
IBD DBSLMM.PseudoVal All.MultiPRS 0.131 0.146 -0.015 3.45e-02 0.135 0.151 -0.016 4.88e-04
IBD SBLUP.Inf All.MultiPRS 0.098 0.146 -0.048 8.60e-12 0.102 0.151 -0.049 5.67e-10
IBD SBayesR.PseudoVal DBSLMM.PseudoVal 0.122 0.131 -0.009 5.95e-03 0.130 0.135 -0.005 4.09e-01
IBD LDpred2.Inf DBSLMM.PseudoVal 0.096 0.131 -0.035 1.11e-15 0.099 0.135 -0.036 2.78e-05
IBD pT+clump.10FCVal DBSLMM.PseudoVal 0.112 0.131 -0.019 3.83e-07 0.112 0.135 -0.023 2.20e-03
IBD PRScs.10FCVal DBSLMM.PseudoVal 0.129 0.131 -0.002 4.92e-01 0.133 0.135 -0.002 6.91e-01
IBD PRScs.PseudoVal DBSLMM.PseudoVal 0.130 0.131 -0.001 7.21e-01 0.128 0.135 -0.007 2.01e-01
IBD pT+clump.MultiPRS DBSLMM.PseudoVal 0.128 0.131 -0.003 6.96e-01 0.137 0.135 0.002 7.37e-01
IBD LDpred1.Inf DBSLMM.PseudoVal 0.100 0.131 -0.031 6.18e-13 0.104 0.135 -0.031 2.85e-04
IBD lassosum.MultiPRS DBSLMM.PseudoVal 0.142 0.131 0.012 9.45e-02 0.146 0.135 0.010 3.19e-02
IBD LDpred2.10FCVal DBSLMM.PseudoVal 0.143 0.131 0.012 1.05e-06 0.145 0.135 0.010 4.05e-02
IBD lassosum.10FCVal DBSLMM.PseudoVal 0.134 0.131 0.004 2.77e-01 0.136 0.135 0.000 9.50e-01
IBD LDpred1.10FCVal DBSLMM.PseudoVal 0.130 0.131 -0.001 7.63e-01 0.134 0.135 -0.001 8.85e-01
IBD LDpred1.MultiPRS DBSLMM.PseudoVal 0.131 0.131 0.001 9.31e-01 0.137 0.135 0.002 7.29e-01
IBD PRScs.MultiPRS DBSLMM.PseudoVal 0.135 0.131 0.005 5.18e-01 0.137 0.135 0.002 5.89e-01
IBD All.MultiPRS DBSLMM.PseudoVal 0.146 0.131 0.015 3.45e-02 0.151 0.135 0.016 4.88e-04
IBD LDpred2.PseudoVal DBSLMM.PseudoVal 0.100 0.131 -0.031 5.01e-14 0.103 0.135 -0.032 8.99e-05
IBD DBSLMM.PseudoVal DBSLMM.PseudoVal 0.131 0.131 0.000 1.00e+00 0.135 0.135 0.000 1.00e+00
IBD LDpred2.MultiPRS DBSLMM.PseudoVal 0.143 0.131 0.012 8.02e-02 0.148 0.135 0.013 5.37e-03
IBD lassosum.PseudoVal DBSLMM.PseudoVal 0.134 0.131 0.003 3.11e-01 0.137 0.135 0.001 8.16e-01
IBD SBLUP.Inf DBSLMM.PseudoVal 0.098 0.131 -0.033 2.73e-14 0.102 0.135 -0.034 1.06e-04
IBD SBayesR.PseudoVal lassosum.MultiPRS 0.122 0.142 -0.020 3.76e-03 0.130 0.146 -0.016 6.98e-03
IBD LDpred2.10FCVal lassosum.MultiPRS 0.143 0.142 0.001 9.39e-01 0.145 0.146 0.000 9.51e-01
IBD LDpred1.10FCVal lassosum.MultiPRS 0.130 0.142 -0.013 7.10e-02 0.134 0.146 -0.011 2.48e-02
IBD LDpred2.Inf lassosum.MultiPRS 0.096 0.142 -0.046 3.78e-11 0.099 0.146 -0.047 5.28e-09
IBD PRScs.10FCVal lassosum.MultiPRS 0.129 0.142 -0.014 5.04e-02 0.133 0.146 -0.013 7.49e-03
IBD PRScs.MultiPRS lassosum.MultiPRS 0.135 0.142 -0.007 2.30e-04 0.137 0.146 -0.008 3.75e-02
IBD pT+clump.MultiPRS lassosum.MultiPRS 0.128 0.142 -0.014 3.84e-02 0.137 0.146 -0.008 9.83e-02
IBD lassosum.MultiPRS lassosum.MultiPRS 0.142 0.142 0.000 1.00e+00 0.146 0.146 0.000 1.00e+00
IBD lassosum.PseudoVal lassosum.MultiPRS 0.134 0.142 -0.009 2.14e-01 0.137 0.146 -0.009 8.44e-03
IBD LDpred2.MultiPRS lassosum.MultiPRS 0.143 0.142 0.001 7.26e-01 0.148 0.146 0.002 4.40e-01
IBD LDpred1.MultiPRS lassosum.MultiPRS 0.131 0.142 -0.011 4.87e-06 0.137 0.146 -0.008 7.81e-02
IBD LDpred2.PseudoVal lassosum.MultiPRS 0.100 0.142 -0.043 1.15e-09 0.103 0.146 -0.043 2.14e-08
IBD LDpred1.Inf lassosum.MultiPRS 0.100 0.142 -0.042 1.59e-09 0.104 0.146 -0.041 1.42e-07
IBD pT+clump.10FCVal lassosum.MultiPRS 0.112 0.142 -0.031 1.06e-05 0.112 0.146 -0.033 2.99e-06
IBD lassosum.10FCVal lassosum.MultiPRS 0.134 0.142 -0.008 2.45e-01 0.136 0.146 -0.010 2.62e-03
IBD SBLUP.Inf lassosum.MultiPRS 0.098 0.142 -0.045 1.65e-10 0.102 0.146 -0.044 2.46e-08
IBD DBSLMM.PseudoVal lassosum.MultiPRS 0.131 0.142 -0.012 9.45e-02 0.135 0.146 -0.010 3.19e-02
IBD All.MultiPRS lassosum.MultiPRS 0.146 0.142 0.003 5.78e-03 0.151 0.146 0.005 2.40e-02
IBD PRScs.PseudoVal lassosum.MultiPRS 0.130 0.142 -0.013 6.88e-02 0.128 0.146 -0.018 2.05e-04
IBD LDpred1.Inf lassosum.PseudoVal 0.100 0.134 -0.034 8.55e-12 0.104 0.137 -0.032 1.04e-03
IBD PRScs.10FCVal lassosum.PseudoVal 0.129 0.134 -0.005 1.37e-01 0.133 0.137 -0.004 5.86e-01
IBD LDpred2.MultiPRS lassosum.PseudoVal 0.143 0.134 0.009 1.87e-01 0.148 0.137 0.011 5.80e-03
IBD lassosum.PseudoVal lassosum.PseudoVal 0.134 0.134 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
IBD PRScs.PseudoVal lassosum.PseudoVal 0.130 0.134 -0.004 2.35e-01 0.128 0.137 -0.009 2.00e-01
IBD DBSLMM.PseudoVal lassosum.PseudoVal 0.131 0.134 -0.003 3.11e-01 0.135 0.137 -0.001 8.16e-01
IBD SBLUP.Inf lassosum.PseudoVal 0.098 0.134 -0.036 9.64e-13 0.102 0.137 -0.035 5.22e-04
IBD LDpred2.Inf lassosum.PseudoVal 0.096 0.134 -0.038 8.86e-14 0.099 0.137 -0.038 1.91e-04
IBD pT+clump.10FCVal lassosum.PseudoVal 0.112 0.134 -0.022 3.58e-11 0.112 0.137 -0.024 2.77e-04
IBD LDpred2.10FCVal lassosum.PseudoVal 0.143 0.134 0.009 6.85e-07 0.145 0.137 0.009 1.86e-02
IBD lassosum.MultiPRS lassosum.PseudoVal 0.142 0.134 0.009 2.14e-01 0.146 0.137 0.009 8.44e-03
IBD LDpred1.10FCVal lassosum.PseudoVal 0.130 0.134 -0.004 2.60e-01 0.134 0.137 -0.002 7.44e-01
IBD All.MultiPRS lassosum.PseudoVal 0.146 0.134 0.012 9.17e-02 0.151 0.137 0.014 6.95e-04
IBD SBayesR.PseudoVal lassosum.PseudoVal 0.122 0.134 -0.012 5.37e-05 0.130 0.137 -0.007 2.48e-01
IBD lassosum.10FCVal lassosum.PseudoVal 0.134 0.134 0.001 7.74e-01 0.136 0.137 -0.001 7.92e-01
IBD pT+clump.MultiPRS lassosum.PseudoVal 0.128 0.134 -0.006 4.10e-01 0.137 0.137 0.001 9.24e-01
IBD LDpred2.PseudoVal lassosum.PseudoVal 0.100 0.134 -0.034 2.12e-12 0.103 0.137 -0.034 4.99e-04
IBD LDpred1.MultiPRS lassosum.PseudoVal 0.131 0.134 -0.002 7.28e-01 0.137 0.137 0.001 9.26e-01
IBD PRScs.MultiPRS lassosum.PseudoVal 0.135 0.134 0.001 8.31e-01 0.137 0.137 0.001 8.65e-01
IBD lassosum.10FCVal lassosum.10FCVal 0.134 0.134 0.000 1.00e+00 0.136 0.136 0.000 1.00e+00
IBD pT+clump.MultiPRS lassosum.10FCVal 0.128 0.134 -0.006 3.66e-01 0.137 0.136 0.002 7.90e-01
IBD LDpred2.Inf lassosum.10FCVal 0.096 0.134 -0.038 1.28e-19 0.099 0.136 -0.037 1.46e-05
IBD SBayesR.PseudoVal lassosum.10FCVal 0.122 0.134 -0.012 3.13e-04 0.130 0.136 -0.006 4.07e-01
IBD PRScs.MultiPRS lassosum.10FCVal 0.135 0.134 0.001 8.93e-01 0.137 0.136 0.002 7.13e-01
IBD SBLUP.Inf lassosum.10FCVal 0.098 0.134 -0.037 2.49e-18 0.102 0.136 -0.034 5.12e-05
IBD lassosum.MultiPRS lassosum.10FCVal 0.142 0.134 0.008 2.45e-01 0.146 0.136 0.010 2.62e-03
IBD PRScs.10FCVal lassosum.10FCVal 0.129 0.134 -0.006 4.49e-02 0.133 0.136 -0.003 6.32e-01
IBD LDpred2.MultiPRS lassosum.10FCVal 0.143 0.134 0.009 2.15e-01 0.148 0.136 0.012 3.63e-03
IBD PRScs.PseudoVal lassosum.10FCVal 0.130 0.134 -0.005 9.96e-02 0.128 0.136 -0.008 1.69e-01
IBD LDpred2.PseudoVal lassosum.10FCVal 0.100 0.134 -0.035 1.07e-17 0.103 0.136 -0.033 5.44e-05
IBD LDpred1.MultiPRS lassosum.10FCVal 0.131 0.134 -0.003 6.70e-01 0.137 0.136 0.002 7.73e-01
IBD pT+clump.10FCVal lassosum.10FCVal 0.112 0.134 -0.023 2.18e-08 0.112 0.136 -0.023 3.88e-03
IBD All.MultiPRS lassosum.10FCVal 0.146 0.134 0.011 1.08e-01 0.151 0.136 0.015 3.09e-04
IBD LDpred1.Inf lassosum.10FCVal 0.100 0.134 -0.034 2.23e-16 0.104 0.136 -0.031 1.82e-04
IBD DBSLMM.PseudoVal lassosum.10FCVal 0.131 0.134 -0.004 2.77e-01 0.135 0.136 0.000 9.50e-01
IBD LDpred1.10FCVal lassosum.10FCVal 0.130 0.134 -0.004 1.23e-01 0.134 0.136 -0.001 8.26e-01
IBD lassosum.PseudoVal lassosum.10FCVal 0.134 0.134 -0.001 7.74e-01 0.137 0.136 0.001 7.92e-01
IBD LDpred2.10FCVal lassosum.10FCVal 0.143 0.134 0.009 5.93e-05 0.145 0.136 0.010 2.26e-02
IBD LDpred2.10FCVal LDpred1.MultiPRS 0.143 0.131 0.012 9.54e-02 0.145 0.137 0.008 1.09e-01
IBD PRScs.PseudoVal LDpred1.MultiPRS 0.130 0.131 -0.002 8.16e-01 0.128 0.137 -0.009 1.37e-02
IBD LDpred2.Inf LDpred1.MultiPRS 0.096 0.131 -0.035 5.13e-07 0.099 0.137 -0.038 3.73e-11
IBD pT+clump.10FCVal LDpred1.MultiPRS 0.112 0.131 -0.020 4.81e-03 0.112 0.137 -0.025 3.53e-03
IBD SBayesR.PseudoVal LDpred1.MultiPRS 0.122 0.131 -0.009 1.91e-01 0.130 0.137 -0.007 2.90e-01
IBD All.MultiPRS LDpred1.MultiPRS 0.146 0.131 0.014 3.85e-10 0.151 0.137 0.013 2.45e-03
IBD LDpred1.10FCVal LDpred1.MultiPRS 0.130 0.131 -0.002 8.28e-01 0.134 0.137 -0.003 2.83e-02
IBD LDpred1.MultiPRS LDpred1.MultiPRS 0.131 0.131 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
IBD PRScs.10FCVal LDpred1.MultiPRS 0.129 0.131 -0.003 7.13e-01 0.133 0.137 -0.004 2.59e-01
IBD lassosum.PseudoVal LDpred1.MultiPRS 0.134 0.131 0.002 7.28e-01 0.137 0.137 -0.001 9.26e-01
IBD pT+clump.MultiPRS LDpred1.MultiPRS 0.128 0.131 -0.003 6.32e-01 0.137 0.137 0.000 9.93e-01
IBD LDpred1.Inf LDpred1.MultiPRS 0.100 0.131 -0.031 8.98e-06 0.104 0.137 -0.033 1.21e-11
IBD lassosum.MultiPRS LDpred1.MultiPRS 0.142 0.131 0.011 4.87e-06 0.146 0.137 0.008 7.81e-02
IBD PRScs.MultiPRS LDpred1.MultiPRS 0.135 0.131 0.004 4.74e-02 0.137 0.137 0.000 9.29e-01
IBD lassosum.10FCVal LDpred1.MultiPRS 0.134 0.131 0.003 6.70e-01 0.136 0.137 -0.002 7.73e-01
IBD LDpred2.PseudoVal LDpred1.MultiPRS 0.100 0.131 -0.032 6.87e-06 0.103 0.137 -0.034 1.36e-10
IBD DBSLMM.PseudoVal LDpred1.MultiPRS 0.131 0.131 -0.001 9.31e-01 0.135 0.137 -0.002 7.29e-01
IBD LDpred2.MultiPRS LDpred1.MultiPRS 0.143 0.131 0.012 2.01e-07 0.148 0.137 0.011 1.36e-02
IBD SBLUP.Inf LDpred1.MultiPRS 0.098 0.131 -0.034 1.59e-06 0.102 0.137 -0.036 5.31e-10
IBD All.MultiPRS LDpred1.Inf 0.146 0.100 0.045 9.52e-11 0.151 0.104 0.046 2.48e-09
IBD LDpred2.PseudoVal LDpred1.Inf 0.100 0.100 0.000 7.79e-01 0.103 0.104 -0.001 6.52e-01
IBD SBayesR.PseudoVal LDpred1.Inf 0.122 0.100 0.022 5.19e-06 0.130 0.104 0.026 8.42e-03
IBD LDpred2.MultiPRS LDpred1.Inf 0.143 0.100 0.043 1.00e-09 0.148 0.104 0.044 3.44e-08
IBD PRScs.PseudoVal LDpred1.Inf 0.130 0.100 0.030 3.08e-26 0.128 0.104 0.023 2.67e-05
IBD LDpred1.Inf LDpred1.Inf 0.100 0.100 0.000 1.00e+00 0.104 0.104 0.000 1.00e+00
IBD pT+clump.10FCVal LDpred1.Inf 0.112 0.100 0.011 3.66e-02 0.112 0.104 0.008 4.73e-01
IBD PRScs.MultiPRS LDpred1.Inf 0.135 0.100 0.035 5.71e-07 0.137 0.104 0.033 1.28e-06
IBD lassosum.PseudoVal LDpred1.Inf 0.134 0.100 0.034 8.55e-12 0.137 0.104 0.032 1.04e-03
IBD pT+clump.MultiPRS LDpred1.Inf 0.128 0.100 0.028 6.84e-05 0.137 0.104 0.033 9.33e-05
IBD LDpred1.MultiPRS LDpred1.Inf 0.131 0.100 0.031 8.98e-06 0.137 0.104 0.033 1.21e-11
IBD PRScs.10FCVal LDpred1.Inf 0.129 0.100 0.029 1.33e-23 0.133 0.104 0.029 4.76e-07
IBD LDpred2.Inf LDpred1.Inf 0.096 0.100 -0.004 9.05e-03 0.099 0.104 -0.005 8.81e-02
IBD SBLUP.Inf LDpred1.Inf 0.098 0.100 -0.003 1.14e-01 0.102 0.104 -0.003 3.85e-01
IBD DBSLMM.PseudoVal LDpred1.Inf 0.131 0.100 0.031 6.18e-13 0.135 0.104 0.031 2.85e-04
IBD lassosum.MultiPRS LDpred1.Inf 0.142 0.100 0.042 1.59e-09 0.146 0.104 0.041 1.42e-07
IBD LDpred1.10FCVal LDpred1.Inf 0.130 0.100 0.030 3.19e-46 0.134 0.104 0.030 6.93e-13
IBD lassosum.10FCVal LDpred1.Inf 0.134 0.100 0.034 2.23e-16 0.136 0.104 0.031 1.82e-04
IBD LDpred2.10FCVal LDpred1.Inf 0.143 0.100 0.043 5.37e-23 0.145 0.104 0.041 2.09e-06
IBD LDpred1.Inf LDpred1.10FCVal 0.100 0.130 -0.030 3.19e-46 0.104 0.134 -0.030 6.93e-13
IBD PRScs.MultiPRS LDpred1.10FCVal 0.135 0.130 0.005 4.37e-01 0.137 0.134 0.003 4.20e-01
IBD LDpred1.10FCVal LDpred1.10FCVal 0.130 0.130 0.000 1.00e+00 0.134 0.134 0.000 1.00e+00
IBD All.MultiPRS LDpred1.10FCVal 0.146 0.130 0.016 2.46e-02 0.151 0.134 0.016 5.90e-04
IBD SBayesR.PseudoVal LDpred1.10FCVal 0.122 0.130 -0.008 3.13e-02 0.130 0.134 -0.004 5.44e-01
IBD DBSLMM.PseudoVal LDpred1.10FCVal 0.131 0.130 0.001 7.63e-01 0.135 0.134 0.001 8.85e-01
IBD pT+clump.MultiPRS LDpred1.10FCVal 0.128 0.130 -0.002 7.94e-01 0.137 0.134 0.003 6.46e-01
IBD lassosum.MultiPRS LDpred1.10FCVal 0.142 0.130 0.013 7.10e-02 0.146 0.134 0.011 2.48e-02
IBD PRScs.10FCVal LDpred1.10FCVal 0.129 0.130 -0.001 5.65e-01 0.133 0.134 -0.001 7.01e-01
IBD lassosum.10FCVal LDpred1.10FCVal 0.134 0.130 0.004 1.23e-01 0.136 0.134 0.001 8.26e-01
IBD SBLUP.Inf LDpred1.10FCVal 0.098 0.130 -0.032 1.52e-34 0.102 0.134 -0.033 3.45e-10
IBD LDpred2.PseudoVal LDpred1.10FCVal 0.100 0.130 -0.030 7.70e-36 0.103 0.134 -0.031 7.10e-11
IBD pT+clump.10FCVal LDpred1.10FCVal 0.112 0.130 -0.018 4.74e-05 0.112 0.134 -0.022 1.27e-02
IBD LDpred2.MultiPRS LDpred1.10FCVal 0.143 0.130 0.013 5.97e-02 0.148 0.134 0.014 3.70e-03
IBD PRScs.PseudoVal LDpred1.10FCVal 0.130 0.130 0.000 9.50e-01 0.128 0.134 -0.006 7.48e-02
IBD LDpred2.10FCVal LDpred1.10FCVal 0.143 0.130 0.013 2.26e-06 0.145 0.134 0.011 4.34e-02
IBD LDpred1.MultiPRS LDpred1.10FCVal 0.131 0.130 0.002 8.28e-01 0.137 0.134 0.003 2.83e-02
IBD LDpred2.Inf LDpred1.10FCVal 0.096 0.130 -0.034 1.35e-37 0.099 0.134 -0.035 1.75e-11
IBD lassosum.PseudoVal LDpred1.10FCVal 0.134 0.130 0.004 2.60e-01 0.137 0.134 0.002 7.44e-01
IBD LDpred1.Inf LDpred2.MultiPRS 0.100 0.143 -0.043 1.00e-09 0.104 0.148 -0.044 3.44e-08
IBD DBSLMM.PseudoVal LDpred2.MultiPRS 0.131 0.143 -0.012 8.02e-02 0.135 0.148 -0.013 5.37e-03
IBD SBLUP.Inf LDpred2.MultiPRS 0.098 0.143 -0.045 1.03e-10 0.102 0.148 -0.046 7.79e-09
IBD LDpred2.Inf LDpred2.MultiPRS 0.096 0.143 -0.047 2.32e-11 0.099 0.148 -0.049 9.28e-10
IBD pT+clump.10FCVal LDpred2.MultiPRS 0.112 0.143 -0.031 7.28e-06 0.112 0.148 -0.036 2.91e-07
IBD LDpred2.10FCVal LDpred2.MultiPRS 0.143 0.143 0.000 9.97e-01 0.145 0.148 -0.003 5.07e-02
IBD PRScs.PseudoVal LDpred2.MultiPRS 0.130 0.143 -0.013 5.78e-02 0.128 0.148 -0.020 1.22e-05
IBD LDpred1.10FCVal LDpred2.MultiPRS 0.130 0.143 -0.013 5.97e-02 0.134 0.148 -0.014 3.70e-03
IBD All.MultiPRS LDpred2.MultiPRS 0.146 0.143 0.003 4.68e-03 0.151 0.148 0.003 1.30e-01
IBD SBayesR.PseudoVal LDpred2.MultiPRS 0.122 0.143 -0.021 2.93e-03 0.130 0.148 -0.018 6.92e-04
IBD lassosum.10FCVal LDpred2.MultiPRS 0.134 0.143 -0.009 2.15e-01 0.136 0.148 -0.012 3.63e-03
IBD pT+clump.MultiPRS LDpred2.MultiPRS 0.128 0.143 -0.015 3.18e-02 0.137 0.148 -0.011 3.66e-02
IBD lassosum.MultiPRS LDpred2.MultiPRS 0.142 0.143 -0.001 7.26e-01 0.146 0.148 -0.002 4.40e-01
IBD PRScs.10FCVal LDpred2.MultiPRS 0.129 0.143 -0.014 4.20e-02 0.133 0.148 -0.015 7.61e-04
IBD PRScs.MultiPRS LDpred2.MultiPRS 0.135 0.143 -0.008 1.43e-05 0.137 0.148 -0.010 2.96e-03
IBD lassosum.PseudoVal LDpred2.MultiPRS 0.134 0.143 -0.009 1.87e-01 0.137 0.148 -0.011 5.80e-03
IBD LDpred2.PseudoVal LDpred2.MultiPRS 0.100 0.143 -0.043 7.24e-10 0.103 0.148 -0.045 2.56e-09
IBD LDpred1.MultiPRS LDpred2.MultiPRS 0.131 0.143 -0.012 2.01e-07 0.137 0.148 -0.011 1.36e-02
IBD LDpred2.MultiPRS LDpred2.MultiPRS 0.143 0.143 0.000 1.00e+00 0.148 0.148 0.000 1.00e+00
IBD LDpred1.Inf LDpred2.10FCVal 0.100 0.143 -0.043 5.37e-23 0.104 0.145 -0.041 2.09e-06
IBD PRScs.MultiPRS LDpred2.10FCVal 0.135 0.143 -0.008 2.69e-01 0.137 0.145 -0.008 6.25e-02
IBD LDpred2.MultiPRS LDpred2.10FCVal 0.143 0.143 0.000 9.97e-01 0.148 0.145 0.003 5.07e-02
IBD PRScs.PseudoVal LDpred2.10FCVal 0.130 0.143 -0.013 8.11e-07 0.128 0.145 -0.018 1.05e-03
IBD LDpred2.10FCVal LDpred2.10FCVal 0.143 0.143 0.000 1.00e+00 0.145 0.145 0.000 1.00e+00
IBD lassosum.MultiPRS LDpred2.10FCVal 0.142 0.143 -0.001 9.39e-01 0.146 0.145 0.000 9.51e-01
IBD LDpred1.10FCVal LDpred2.10FCVal 0.130 0.143 -0.013 2.26e-06 0.134 0.145 -0.011 4.34e-02
IBD All.MultiPRS LDpred2.10FCVal 0.146 0.143 0.003 7.13e-01 0.151 0.145 0.005 2.18e-02
IBD SBayesR.PseudoVal LDpred2.10FCVal 0.122 0.143 -0.021 8.56e-15 0.130 0.145 -0.015 4.05e-03
IBD DBSLMM.PseudoVal LDpred2.10FCVal 0.131 0.143 -0.012 1.05e-06 0.135 0.145 -0.010 4.05e-02
IBD pT+clump.MultiPRS LDpred2.10FCVal 0.128 0.143 -0.015 3.22e-02 0.137 0.145 -0.008 1.27e-01
IBD lassosum.PseudoVal LDpred2.10FCVal 0.134 0.143 -0.009 6.85e-07 0.137 0.145 -0.009 1.86e-02
IBD PRScs.10FCVal LDpred2.10FCVal 0.129 0.143 -0.014 7.53e-08 0.133 0.145 -0.012 1.75e-02
IBD lassosum.10FCVal LDpred2.10FCVal 0.134 0.143 -0.009 5.93e-05 0.136 0.145 -0.010 2.26e-02
IBD SBLUP.Inf LDpred2.10FCVal 0.098 0.143 -0.045 2.29e-24 0.102 0.145 -0.044 7.02e-07
IBD LDpred2.PseudoVal LDpred2.10FCVal 0.100 0.143 -0.043 8.00e-25 0.103 0.145 -0.042 3.76e-07
IBD pT+clump.10FCVal LDpred2.10FCVal 0.112 0.143 -0.031 1.07e-20 0.112 0.145 -0.033 7.17e-07
IBD LDpred2.Inf LDpred2.10FCVal 0.096 0.143 -0.047 3.12e-26 0.099 0.145 -0.046 1.31e-07
IBD LDpred1.MultiPRS LDpred2.10FCVal 0.131 0.143 -0.012 9.54e-02 0.137 0.145 -0.008 1.09e-01
IBD lassosum.10FCVal LDpred2.PseudoVal 0.134 0.100 0.035 1.07e-17 0.136 0.103 0.033 5.44e-05
IBD SBLUP.Inf LDpred2.PseudoVal 0.098 0.100 -0.002 1.13e-02 0.102 0.103 -0.001 4.08e-01
IBD SBayesR.PseudoVal LDpred2.PseudoVal 0.122 0.100 0.023 3.30e-06 0.130 0.103 0.027 5.52e-03
IBD All.MultiPRS LDpred2.PseudoVal 0.146 0.100 0.046 6.78e-11 0.151 0.103 0.048 3.06e-10
IBD PRScs.PseudoVal LDpred2.PseudoVal 0.130 0.100 0.030 3.68e-33 0.128 0.103 0.025 6.09e-07
IBD lassosum.MultiPRS LDpred2.PseudoVal 0.142 0.100 0.043 1.15e-09 0.146 0.103 0.043 2.14e-08
IBD PRScs.MultiPRS LDpred2.PseudoVal 0.135 0.100 0.036 4.27e-07 0.137 0.103 0.035 8.23e-08
IBD LDpred2.MultiPRS LDpred2.PseudoVal 0.143 0.100 0.043 7.24e-10 0.148 0.103 0.045 2.56e-09
IBD PRScs.10FCVal LDpred2.PseudoVal 0.129 0.100 0.029 5.76e-30 0.133 0.103 0.030 2.87e-09
IBD LDpred2.PseudoVal LDpred2.PseudoVal 0.100 0.100 0.000 1.00e+00 0.103 0.103 0.000 1.00e+00
IBD pT+clump.MultiPRS LDpred2.PseudoVal 0.128 0.100 0.028 5.25e-05 0.137 0.103 0.034 3.40e-05
IBD pT+clump.10FCVal LDpred2.PseudoVal 0.112 0.100 0.012 2.91e-02 0.112 0.103 0.009 3.94e-01
IBD lassosum.PseudoVal LDpred2.PseudoVal 0.134 0.100 0.034 2.12e-12 0.137 0.103 0.034 4.99e-04
IBD LDpred1.Inf LDpred2.PseudoVal 0.100 0.100 0.000 7.79e-01 0.104 0.103 0.001 6.52e-01
IBD LDpred1.MultiPRS LDpred2.PseudoVal 0.131 0.100 0.032 6.87e-06 0.137 0.103 0.034 1.36e-10
IBD LDpred1.10FCVal LDpred2.PseudoVal 0.130 0.100 0.030 7.70e-36 0.134 0.103 0.031 7.10e-11
IBD LDpred2.Inf LDpred2.PseudoVal 0.096 0.100 -0.004 4.59e-18 0.099 0.103 -0.004 2.49e-06
IBD LDpred2.10FCVal LDpred2.PseudoVal 0.143 0.100 0.043 8.00e-25 0.145 0.103 0.042 3.76e-07
IBD DBSLMM.PseudoVal LDpred2.PseudoVal 0.131 0.100 0.031 5.01e-14 0.135 0.103 0.032 8.99e-05
IBD pT+clump.MultiPRS LDpred2.Inf 0.128 0.096 0.032 4.85e-06 0.137 0.099 0.038 1.02e-05
IBD lassosum.MultiPRS LDpred2.Inf 0.142 0.096 0.046 3.78e-11 0.146 0.099 0.047 5.28e-09
IBD SBayesR.PseudoVal LDpred2.Inf 0.122 0.096 0.026 2.07e-07 0.130 0.099 0.031 2.23e-03
IBD All.MultiPRS LDpred2.Inf 0.146 0.096 0.050 1.80e-12 0.151 0.099 0.052 8.38e-11
IBD SBLUP.Inf LDpred2.Inf 0.098 0.096 0.002 9.96e-03 0.102 0.099 0.003 3.32e-02
IBD LDpred2.PseudoVal LDpred2.Inf 0.100 0.096 0.004 4.59e-18 0.103 0.099 0.004 2.49e-06
IBD PRScs.MultiPRS LDpred2.Inf 0.135 0.096 0.039 2.40e-08 0.137 0.099 0.039 2.49e-08
IBD LDpred2.MultiPRS LDpred2.Inf 0.143 0.096 0.047 2.32e-11 0.148 0.099 0.049 9.28e-10
IBD PRScs.10FCVal LDpred2.Inf 0.129 0.096 0.033 1.97e-32 0.133 0.099 0.034 4.51e-10
IBD LDpred1.Inf LDpred2.Inf 0.100 0.096 0.004 9.05e-03 0.104 0.099 0.005 8.81e-02
IBD LDpred1.MultiPRS LDpred2.Inf 0.131 0.096 0.035 5.13e-07 0.137 0.099 0.038 3.73e-11
IBD pT+clump.10FCVal LDpred2.Inf 0.112 0.096 0.016 5.82e-03 0.112 0.099 0.013 2.39e-01
IBD lassosum.PseudoVal LDpred2.Inf 0.134 0.096 0.038 8.86e-14 0.137 0.099 0.038 1.91e-04
IBD PRScs.PseudoVal LDpred2.Inf 0.130 0.096 0.034 8.96e-36 0.128 0.099 0.029 7.38e-08
IBD DBSLMM.PseudoVal LDpred2.Inf 0.131 0.096 0.035 1.11e-15 0.135 0.099 0.036 2.78e-05
IBD LDpred1.10FCVal LDpred2.Inf 0.130 0.096 0.034 1.35e-37 0.134 0.099 0.035 1.75e-11
IBD LDpred2.Inf LDpred2.Inf 0.096 0.096 0.000 1.00e+00 0.099 0.099 0.000 1.00e+00
IBD lassosum.10FCVal LDpred2.Inf 0.134 0.096 0.038 1.28e-19 0.136 0.099 0.037 1.46e-05
IBD LDpred2.10FCVal LDpred2.Inf 0.143 0.096 0.047 3.12e-26 0.145 0.099 0.046 1.31e-07
IBD PRScs.10FCVal PRScs.MultiPRS 0.129 0.135 -0.007 3.53e-01 0.133 0.137 -0.005 1.19e-01
IBD LDpred1.10FCVal PRScs.MultiPRS 0.130 0.135 -0.005 4.37e-01 0.134 0.137 -0.003 4.20e-01
IBD lassosum.MultiPRS PRScs.MultiPRS 0.142 0.135 0.007 2.30e-04 0.146 0.137 0.008 3.75e-02
IBD LDpred2.MultiPRS PRScs.MultiPRS 0.143 0.135 0.008 1.43e-05 0.148 0.137 0.010 2.96e-03
IBD All.MultiPRS PRScs.MultiPRS 0.146 0.135 0.010 1.64e-08 0.151 0.137 0.013 2.70e-04
IBD PRScs.PseudoVal PRScs.MultiPRS 0.130 0.135 -0.006 4.28e-01 0.128 0.137 -0.010 9.56e-04
IBD LDpred1.MultiPRS PRScs.MultiPRS 0.131 0.135 -0.004 4.74e-02 0.137 0.137 0.000 9.29e-01
IBD pT+clump.MultiPRS PRScs.MultiPRS 0.128 0.135 -0.007 2.98e-01 0.137 0.137 0.000 9.43e-01
IBD lassosum.PseudoVal PRScs.MultiPRS 0.134 0.135 -0.001 8.31e-01 0.137 0.137 -0.001 8.65e-01
IBD SBayesR.PseudoVal PRScs.MultiPRS 0.122 0.135 -0.013 6.18e-02 0.130 0.137 -0.008 2.44e-01
IBD DBSLMM.PseudoVal PRScs.MultiPRS 0.131 0.135 -0.005 5.18e-01 0.135 0.137 -0.002 5.89e-01
IBD SBLUP.Inf PRScs.MultiPRS 0.098 0.135 -0.038 8.40e-08 0.102 0.137 -0.036 1.73e-07
IBD LDpred2.Inf PRScs.MultiPRS 0.096 0.135 -0.039 2.40e-08 0.099 0.137 -0.039 2.49e-08
IBD pT+clump.10FCVal PRScs.MultiPRS 0.112 0.135 -0.024 7.24e-04 0.112 0.137 -0.025 1.37e-03
IBD LDpred2.10FCVal PRScs.MultiPRS 0.143 0.135 0.008 2.69e-01 0.145 0.137 0.008 6.25e-02
IBD lassosum.10FCVal PRScs.MultiPRS 0.134 0.135 -0.001 8.93e-01 0.136 0.137 -0.002 7.13e-01
IBD LDpred2.PseudoVal PRScs.MultiPRS 0.100 0.135 -0.036 4.27e-07 0.103 0.137 -0.035 8.23e-08
IBD LDpred1.Inf PRScs.MultiPRS 0.100 0.135 -0.035 5.71e-07 0.104 0.137 -0.033 1.28e-06
IBD PRScs.MultiPRS PRScs.MultiPRS 0.135 0.135 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
IBD LDpred2.PseudoVal PRScs.10FCVal 0.100 0.129 -0.029 5.76e-30 0.103 0.133 -0.030 2.87e-09
IBD PRScs.10FCVal PRScs.10FCVal 0.129 0.129 0.000 1.00e+00 0.133 0.133 0.000 1.00e+00
IBD LDpred2.MultiPRS PRScs.10FCVal 0.143 0.129 0.014 4.20e-02 0.148 0.133 0.015 7.61e-04
IBD pT+clump.MultiPRS PRScs.10FCVal 0.128 0.129 -0.001 9.13e-01 0.137 0.133 0.004 5.02e-01
IBD LDpred1.Inf PRScs.10FCVal 0.100 0.129 -0.029 1.33e-23 0.104 0.133 -0.029 4.76e-07
IBD LDpred1.MultiPRS PRScs.10FCVal 0.131 0.129 0.003 7.13e-01 0.137 0.133 0.004 2.59e-01
IBD pT+clump.10FCVal PRScs.10FCVal 0.112 0.129 -0.017 1.25e-04 0.112 0.133 -0.021 2.03e-02
IBD lassosum.PseudoVal PRScs.10FCVal 0.134 0.129 0.005 1.37e-01 0.137 0.133 0.004 5.86e-01
IBD PRScs.PseudoVal PRScs.10FCVal 0.130 0.129 0.001 5.16e-01 0.128 0.133 -0.005 8.03e-02
IBD DBSLMM.PseudoVal PRScs.10FCVal 0.131 0.129 0.002 4.92e-01 0.135 0.133 0.002 6.91e-01
IBD SBLUP.Inf PRScs.10FCVal 0.098 0.129 -0.031 7.19e-30 0.102 0.133 -0.031 6.60e-09
IBD LDpred2.Inf PRScs.10FCVal 0.096 0.129 -0.033 1.97e-32 0.099 0.133 -0.034 4.51e-10
IBD lassosum.10FCVal PRScs.10FCVal 0.134 0.129 0.006 4.49e-02 0.136 0.133 0.003 6.32e-01
IBD LDpred2.10FCVal PRScs.10FCVal 0.143 0.129 0.014 7.53e-08 0.145 0.133 0.012 1.75e-02
IBD lassosum.MultiPRS PRScs.10FCVal 0.142 0.129 0.014 5.04e-02 0.146 0.133 0.013 7.49e-03
IBD LDpred1.10FCVal PRScs.10FCVal 0.130 0.129 0.001 5.65e-01 0.134 0.133 0.001 7.01e-01
IBD All.MultiPRS PRScs.10FCVal 0.146 0.129 0.017 1.65e-02 0.151 0.133 0.018 1.04e-04
IBD SBayesR.PseudoVal PRScs.10FCVal 0.122 0.129 -0.007 7.72e-02 0.130 0.133 -0.003 6.98e-01
IBD PRScs.MultiPRS PRScs.10FCVal 0.135 0.129 0.007 3.53e-01 0.137 0.133 0.005 1.19e-01
IBD All.MultiPRS PRScs.PseudoVal 0.146 0.130 0.016 2.37e-02 0.151 0.128 0.023 8.64e-07
IBD pT+clump.MultiPRS PRScs.PseudoVal 0.128 0.130 -0.002 8.07e-01 0.137 0.128 0.009 1.44e-01
IBD LDpred2.PseudoVal PRScs.PseudoVal 0.100 0.130 -0.030 3.68e-33 0.103 0.128 -0.025 6.09e-07
IBD SBayesR.PseudoVal PRScs.PseudoVal 0.122 0.130 -0.008 4.60e-02 0.130 0.128 0.002 7.75e-01
IBD LDpred2.MultiPRS PRScs.PseudoVal 0.143 0.130 0.013 5.78e-02 0.148 0.128 0.020 1.22e-05
IBD SBLUP.Inf PRScs.PseudoVal 0.098 0.130 -0.032 3.04e-33 0.102 0.128 -0.026 6.93e-07
IBD LDpred1.Inf PRScs.PseudoVal 0.100 0.130 -0.030 3.08e-26 0.104 0.128 -0.023 2.67e-05
IBD PRScs.10FCVal PRScs.PseudoVal 0.129 0.130 -0.001 5.16e-01 0.133 0.128 0.005 8.03e-02
IBD LDpred2.Inf PRScs.PseudoVal 0.096 0.130 -0.034 8.96e-36 0.099 0.128 -0.029 7.38e-08
IBD PRScs.PseudoVal PRScs.PseudoVal 0.130 0.130 0.000 1.00e+00 0.128 0.128 0.000 1.00e+00
IBD LDpred2.10FCVal PRScs.PseudoVal 0.143 0.130 0.013 8.11e-07 0.145 0.128 0.018 1.05e-03
IBD pT+clump.10FCVal PRScs.PseudoVal 0.112 0.130 -0.018 6.32e-05 0.112 0.128 -0.016 8.35e-02
IBD PRScs.MultiPRS PRScs.PseudoVal 0.135 0.130 0.006 4.28e-01 0.137 0.128 0.010 9.56e-04
IBD lassosum.PseudoVal PRScs.PseudoVal 0.134 0.130 0.004 2.35e-01 0.137 0.128 0.009 2.00e-01
IBD lassosum.10FCVal PRScs.PseudoVal 0.134 0.130 0.005 9.96e-02 0.136 0.128 0.008 1.69e-01
IBD LDpred1.MultiPRS PRScs.PseudoVal 0.131 0.130 0.002 8.16e-01 0.137 0.128 0.009 1.37e-02
IBD lassosum.MultiPRS PRScs.PseudoVal 0.142 0.130 0.013 6.88e-02 0.146 0.128 0.018 2.05e-04
IBD LDpred1.10FCVal PRScs.PseudoVal 0.130 0.130 0.000 9.50e-01 0.134 0.128 0.006 7.48e-02
IBD DBSLMM.PseudoVal PRScs.PseudoVal 0.131 0.130 0.001 7.21e-01 0.135 0.128 0.007 2.01e-01
IBD All.MultiPRS pT+clump.MultiPRS 0.146 0.128 0.018 1.20e-02 0.151 0.137 0.014 4.39e-03
IBD SBayesR.PseudoVal pT+clump.MultiPRS 0.122 0.128 -0.006 4.08e-01 0.130 0.137 -0.007 3.00e-01
IBD LDpred1.MultiPRS pT+clump.MultiPRS 0.131 0.128 0.003 6.32e-01 0.137 0.137 0.000 9.93e-01
IBD pT+clump.MultiPRS pT+clump.MultiPRS 0.128 0.128 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
IBD lassosum.PseudoVal pT+clump.MultiPRS 0.134 0.128 0.006 4.10e-01 0.137 0.137 -0.001 9.24e-01
IBD PRScs.10FCVal pT+clump.MultiPRS 0.129 0.128 0.001 9.13e-01 0.133 0.137 -0.004 5.02e-01
IBD DBSLMM.PseudoVal pT+clump.MultiPRS 0.131 0.128 0.003 6.96e-01 0.135 0.137 -0.002 7.37e-01
IBD SBLUP.Inf pT+clump.MultiPRS 0.098 0.128 -0.030 1.38e-05 0.102 0.137 -0.036 3.59e-05
IBD LDpred2.Inf pT+clump.MultiPRS 0.096 0.128 -0.032 4.85e-06 0.099 0.137 -0.038 1.02e-05
IBD pT+clump.10FCVal pT+clump.MultiPRS 0.112 0.128 -0.016 1.93e-02 0.112 0.137 -0.025 9.88e-07
IBD LDpred2.10FCVal pT+clump.MultiPRS 0.143 0.128 0.015 3.22e-02 0.145 0.137 0.008 1.27e-01
IBD PRScs.PseudoVal pT+clump.MultiPRS 0.130 0.128 0.002 8.07e-01 0.128 0.137 -0.009 1.44e-01
IBD LDpred1.10FCVal pT+clump.MultiPRS 0.130 0.128 0.002 7.94e-01 0.134 0.137 -0.003 6.46e-01
IBD LDpred1.Inf pT+clump.MultiPRS 0.100 0.128 -0.028 6.84e-05 0.104 0.137 -0.033 9.33e-05
IBD PRScs.MultiPRS pT+clump.MultiPRS 0.135 0.128 0.007 2.98e-01 0.137 0.137 0.000 9.43e-01
IBD lassosum.10FCVal pT+clump.MultiPRS 0.134 0.128 0.006 3.66e-01 0.136 0.137 -0.002 7.90e-01
IBD LDpred2.PseudoVal pT+clump.MultiPRS 0.100 0.128 -0.028 5.25e-05 0.103 0.137 -0.034 3.40e-05
IBD lassosum.MultiPRS pT+clump.MultiPRS 0.142 0.128 0.014 3.84e-02 0.146 0.137 0.008 9.83e-02
IBD LDpred2.MultiPRS pT+clump.MultiPRS 0.143 0.128 0.015 3.18e-02 0.148 0.137 0.011 3.66e-02
IBD LDpred2.10FCVal pT+clump.10FCVal 0.143 0.112 0.031 1.07e-20 0.145 0.112 0.033 7.17e-07
IBD pT+clump.MultiPRS pT+clump.10FCVal 0.128 0.112 0.016 1.93e-02 0.137 0.112 0.025 9.88e-07
IBD LDpred2.Inf pT+clump.10FCVal 0.096 0.112 -0.016 5.82e-03 0.099 0.112 -0.013 2.39e-01
IBD SBayesR.PseudoVal pT+clump.10FCVal 0.122 0.112 0.011 4.15e-03 0.130 0.112 0.018 1.55e-02
IBD PRScs.MultiPRS pT+clump.10FCVal 0.135 0.112 0.024 7.24e-04 0.137 0.112 0.025 1.37e-03
IBD SBLUP.Inf pT+clump.10FCVal 0.098 0.112 -0.014 1.37e-02 0.102 0.112 -0.011 3.47e-01
IBD lassosum.MultiPRS pT+clump.10FCVal 0.142 0.112 0.031 1.06e-05 0.146 0.112 0.033 2.99e-06
IBD PRScs.10FCVal pT+clump.10FCVal 0.129 0.112 0.017 1.25e-04 0.133 0.112 0.021 2.03e-02
IBD LDpred2.MultiPRS pT+clump.10FCVal 0.143 0.112 0.031 7.28e-06 0.148 0.112 0.036 2.91e-07
IBD lassosum.10FCVal pT+clump.10FCVal 0.134 0.112 0.023 2.18e-08 0.136 0.112 0.023 3.88e-03
IBD LDpred2.PseudoVal pT+clump.10FCVal 0.100 0.112 -0.012 2.91e-02 0.103 0.112 -0.009 3.94e-01
IBD LDpred1.MultiPRS pT+clump.10FCVal 0.131 0.112 0.020 4.81e-03 0.137 0.112 0.025 3.53e-03
IBD pT+clump.10FCVal pT+clump.10FCVal 0.112 0.112 0.000 1.00e+00 0.112 0.112 0.000 1.00e+00
IBD All.MultiPRS pT+clump.10FCVal 0.146 0.112 0.034 1.23e-06 0.151 0.112 0.038 1.18e-08
IBD LDpred1.Inf pT+clump.10FCVal 0.100 0.112 -0.011 3.66e-02 0.104 0.112 -0.008 4.73e-01
IBD DBSLMM.PseudoVal pT+clump.10FCVal 0.131 0.112 0.019 3.83e-07 0.135 0.112 0.023 2.20e-03
IBD LDpred1.10FCVal pT+clump.10FCVal 0.130 0.112 0.018 4.74e-05 0.134 0.112 0.022 1.27e-02
IBD lassosum.PseudoVal pT+clump.10FCVal 0.134 0.112 0.022 3.58e-11 0.137 0.112 0.024 2.77e-04
IBD PRScs.PseudoVal pT+clump.10FCVal 0.130 0.112 0.018 6.32e-05 0.128 0.112 0.016 8.35e-02
IBD pT+clump.MultiPRS SBayesR.PseudoVal 0.128 0.122 0.006 4.08e-01 0.137 0.130 0.007 3.00e-01
IBD LDpred1.10FCVal SBayesR.PseudoVal 0.130 0.122 0.008 3.13e-02 0.134 0.130 0.004 5.44e-01
IBD PRScs.10FCVal SBayesR.PseudoVal 0.129 0.122 0.007 7.72e-02 0.133 0.130 0.003 6.98e-01
IBD LDpred2.10FCVal SBayesR.PseudoVal 0.143 0.122 0.021 8.56e-15 0.145 0.130 0.015 4.05e-03
IBD lassosum.10FCVal SBayesR.PseudoVal 0.134 0.122 0.012 3.13e-04 0.136 0.130 0.006 4.07e-01
IBD LDpred2.PseudoVal SBayesR.PseudoVal 0.100 0.122 -0.023 3.30e-06 0.103 0.130 -0.027 5.52e-03
IBD lassosum.MultiPRS SBayesR.PseudoVal 0.142 0.122 0.020 3.76e-03 0.146 0.130 0.016 6.98e-03
IBD LDpred2.MultiPRS SBayesR.PseudoVal 0.143 0.122 0.021 2.93e-03 0.148 0.130 0.018 6.92e-04
IBD All.MultiPRS SBayesR.PseudoVal 0.146 0.122 0.023 8.33e-04 0.151 0.130 0.021 1.68e-04
IBD PRScs.PseudoVal SBayesR.PseudoVal 0.130 0.122 0.008 4.60e-02 0.128 0.130 -0.002 7.75e-01
IBD LDpred1.MultiPRS SBayesR.PseudoVal 0.131 0.122 0.009 1.91e-01 0.137 0.130 0.007 2.90e-01
IBD pT+clump.10FCVal SBayesR.PseudoVal 0.112 0.122 -0.011 4.15e-03 0.112 0.130 -0.018 1.55e-02
IBD lassosum.PseudoVal SBayesR.PseudoVal 0.134 0.122 0.012 5.37e-05 0.137 0.130 0.007 2.48e-01
IBD SBayesR.PseudoVal SBayesR.PseudoVal 0.122 0.122 0.000 1.00e+00 0.130 0.130 0.000 1.00e+00
IBD DBSLMM.PseudoVal SBayesR.PseudoVal 0.131 0.122 0.009 5.95e-03 0.135 0.130 0.005 4.09e-01
IBD SBLUP.Inf SBayesR.PseudoVal 0.098 0.122 -0.025 1.19e-06 0.102 0.130 -0.028 5.27e-03
IBD LDpred2.Inf SBayesR.PseudoVal 0.096 0.122 -0.026 2.07e-07 0.099 0.130 -0.031 2.23e-03
IBD LDpred1.Inf SBayesR.PseudoVal 0.100 0.122 -0.022 5.19e-06 0.104 0.130 -0.026 8.42e-03
IBD PRScs.MultiPRS SBayesR.PseudoVal 0.135 0.122 0.013 6.18e-02 0.137 0.130 0.008 2.44e-01
IBD LDpred2.10FCVal SBLUP.Inf 0.143 0.098 0.045 2.29e-24 0.145 0.102 0.044 7.02e-07
IBD PRScs.PseudoVal SBLUP.Inf 0.130 0.098 0.032 3.04e-33 0.128 0.102 0.026 6.93e-07
IBD LDpred1.10FCVal SBLUP.Inf 0.130 0.098 0.032 1.52e-34 0.134 0.102 0.033 3.45e-10
IBD LDpred2.Inf SBLUP.Inf 0.096 0.098 -0.002 9.96e-03 0.099 0.102 -0.003 3.32e-02
IBD SBayesR.PseudoVal SBLUP.Inf 0.122 0.098 0.025 1.19e-06 0.130 0.102 0.028 5.27e-03
IBD lassosum.10FCVal SBLUP.Inf 0.134 0.098 0.037 2.49e-18 0.136 0.102 0.034 5.12e-05
IBD pT+clump.MultiPRS SBLUP.Inf 0.128 0.098 0.030 1.38e-05 0.137 0.102 0.036 3.59e-05
IBD lassosum.MultiPRS SBLUP.Inf 0.142 0.098 0.045 1.65e-10 0.146 0.102 0.044 2.46e-08
IBD PRScs.10FCVal SBLUP.Inf 0.129 0.098 0.031 7.19e-30 0.133 0.102 0.031 6.60e-09
IBD PRScs.MultiPRS SBLUP.Inf 0.135 0.098 0.038 8.40e-08 0.137 0.102 0.036 1.73e-07
IBD LDpred1.MultiPRS SBLUP.Inf 0.131 0.098 0.034 1.59e-06 0.137 0.102 0.036 5.31e-10
IBD LDpred2.PseudoVal SBLUP.Inf 0.100 0.098 0.002 1.13e-02 0.103 0.102 0.001 4.08e-01
IBD LDpred1.Inf SBLUP.Inf 0.100 0.098 0.003 1.14e-01 0.104 0.102 0.003 3.85e-01
IBD LDpred2.MultiPRS SBLUP.Inf 0.143 0.098 0.045 1.03e-10 0.148 0.102 0.046 7.79e-09
IBD All.MultiPRS SBLUP.Inf 0.146 0.098 0.048 8.60e-12 0.151 0.102 0.049 5.67e-10
IBD SBLUP.Inf SBLUP.Inf 0.098 0.098 0.000 1.00e+00 0.102 0.102 0.000 1.00e+00
IBD DBSLMM.PseudoVal SBLUP.Inf 0.131 0.098 0.033 2.73e-14 0.135 0.102 0.034 1.06e-04
IBD pT+clump.10FCVal SBLUP.Inf 0.112 0.098 0.014 1.37e-02 0.112 0.102 0.011 3.47e-01
IBD lassosum.PseudoVal SBLUP.Inf 0.134 0.098 0.036 9.64e-13 0.137 0.102 0.035 5.22e-04
MultiScler LDpred2.PseudoVal All.MultiPRS 0.101 0.133 -0.032 4.28e-06 0.088 0.121 -0.033 4.34e-05
MultiScler pT+clump.10FCVal All.MultiPRS 0.090 0.133 -0.043 8.56e-10 0.092 0.121 -0.029 4.14e-04
MultiScler LDpred2.MultiPRS All.MultiPRS 0.130 0.133 -0.003 8.80e-03 0.117 0.121 -0.004 1.26e-01
MultiScler PRScs.PseudoVal All.MultiPRS 0.103 0.133 -0.030 1.73e-05 0.101 0.121 -0.020 2.48e-03
MultiScler LDpred1.Inf All.MultiPRS 0.089 0.133 -0.045 2.09e-10 0.081 0.121 -0.040 7.74e-07
MultiScler PRScs.MultiPRS All.MultiPRS 0.118 0.133 -0.015 7.83e-08 0.108 0.121 -0.013 1.71e-02
MultiScler LDpred2.Inf All.MultiPRS 0.092 0.133 -0.041 3.97e-09 0.078 0.121 -0.043 1.43e-06
MultiScler lassosum.10FCVal All.MultiPRS 0.115 0.133 -0.018 1.01e-02 0.102 0.121 -0.019 2.67e-03
MultiScler LDpred2.10FCVal All.MultiPRS 0.112 0.133 -0.021 2.19e-03 0.101 0.121 -0.020 2.34e-04
MultiScler lassosum.MultiPRS All.MultiPRS 0.126 0.133 -0.007 2.93e-04 0.124 0.121 0.003 4.05e-01
MultiScler LDpred1.10FCVal All.MultiPRS 0.103 0.133 -0.030 1.40e-05 0.095 0.121 -0.026 6.90e-05
MultiScler All.MultiPRS All.MultiPRS 0.133 0.133 0.000 1.00e+00 0.121 0.121 0.000 1.00e+00
MultiScler SBayesR.PseudoVal All.MultiPRS 0.100 0.133 -0.034 1.49e-06 0.084 0.121 -0.037 1.99e-06
MultiScler LDpred1.MultiPRS All.MultiPRS 0.103 0.133 -0.030 1.34e-19 0.096 0.121 -0.025 1.32e-04
MultiScler pT+clump.MultiPRS All.MultiPRS 0.114 0.133 -0.019 6.93e-03 0.116 0.121 -0.005 3.17e-01
MultiScler lassosum.PseudoVal All.MultiPRS 0.100 0.133 -0.033 2.34e-06 0.106 0.121 -0.015 2.27e-02
MultiScler PRScs.10FCVal All.MultiPRS 0.118 0.133 -0.016 2.63e-02 0.104 0.121 -0.017 6.52e-03
MultiScler DBSLMM.PseudoVal All.MultiPRS 0.090 0.133 -0.043 7.21e-10 0.085 0.121 -0.036 1.06e-05
MultiScler SBLUP.Inf All.MultiPRS 0.093 0.133 -0.040 8.51e-09 0.079 0.121 -0.042 1.61e-06
MultiScler SBayesR.PseudoVal DBSLMM.PseudoVal 0.100 0.090 0.010 1.22e-01 0.084 0.085 -0.001 9.40e-01
MultiScler LDpred2.Inf DBSLMM.PseudoVal 0.092 0.090 0.002 7.64e-01 0.078 0.085 -0.006 6.18e-01
MultiScler pT+clump.10FCVal DBSLMM.PseudoVal 0.090 0.090 0.000 9.47e-01 0.092 0.085 0.007 3.21e-01
MultiScler PRScs.10FCVal DBSLMM.PseudoVal 0.118 0.090 0.028 3.09e-08 0.104 0.085 0.019 5.58e-02
MultiScler PRScs.PseudoVal DBSLMM.PseudoVal 0.103 0.090 0.013 2.44e-09 0.101 0.085 0.017 1.79e-04
MultiScler pT+clump.MultiPRS DBSLMM.PseudoVal 0.114 0.090 0.024 5.00e-04 0.116 0.085 0.031 3.13e-04
MultiScler LDpred1.Inf DBSLMM.PseudoVal 0.089 0.090 -0.001 7.87e-01 0.081 0.085 -0.004 7.01e-01
MultiScler lassosum.MultiPRS DBSLMM.PseudoVal 0.126 0.090 0.036 2.94e-07 0.124 0.085 0.040 2.57e-07
MultiScler LDpred2.10FCVal DBSLMM.PseudoVal 0.112 0.090 0.022 1.69e-13 0.101 0.085 0.016 6.56e-03
MultiScler lassosum.10FCVal DBSLMM.PseudoVal 0.115 0.090 0.025 3.61e-07 0.102 0.085 0.017 7.84e-02
MultiScler LDpred1.10FCVal DBSLMM.PseudoVal 0.103 0.090 0.013 3.38e-04 0.095 0.085 0.010 1.53e-01
MultiScler LDpred1.MultiPRS DBSLMM.PseudoVal 0.103 0.090 0.013 6.98e-02 0.096 0.085 0.011 1.24e-01
MultiScler PRScs.MultiPRS DBSLMM.PseudoVal 0.118 0.090 0.028 5.80e-05 0.108 0.085 0.023 4.38e-04
MultiScler All.MultiPRS DBSLMM.PseudoVal 0.133 0.090 0.043 7.21e-10 0.121 0.085 0.036 1.06e-05
MultiScler LDpred2.PseudoVal DBSLMM.PseudoVal 0.101 0.090 0.011 6.67e-02 0.088 0.085 0.003 7.77e-01
MultiScler DBSLMM.PseudoVal DBSLMM.PseudoVal 0.090 0.090 0.000 1.00e+00 0.085 0.085 0.000 1.00e+00
MultiScler LDpred2.MultiPRS DBSLMM.PseudoVal 0.130 0.090 0.040 1.40e-08 0.117 0.085 0.032 1.71e-04
MultiScler lassosum.PseudoVal DBSLMM.PseudoVal 0.100 0.090 0.010 1.26e-05 0.106 0.085 0.021 1.02e-05
MultiScler SBLUP.Inf DBSLMM.PseudoVal 0.093 0.090 0.003 6.58e-01 0.079 0.085 -0.006 6.47e-01
MultiScler SBayesR.PseudoVal lassosum.MultiPRS 0.100 0.126 -0.026 1.64e-04 0.084 0.124 -0.041 7.10e-06
MultiScler LDpred2.10FCVal lassosum.MultiPRS 0.112 0.126 -0.014 4.28e-02 0.101 0.124 -0.023 2.36e-04
MultiScler LDpred1.10FCVal lassosum.MultiPRS 0.103 0.126 -0.023 9.32e-04 0.095 0.124 -0.029 3.53e-07
MultiScler LDpred2.Inf lassosum.MultiPRS 0.092 0.126 -0.034 1.26e-06 0.078 0.124 -0.046 3.23e-08
MultiScler PRScs.10FCVal lassosum.MultiPRS 0.118 0.126 -0.008 2.36e-01 0.104 0.124 -0.021 8.05e-05
MultiScler PRScs.MultiPRS lassosum.MultiPRS 0.118 0.126 -0.008 4.13e-05 0.108 0.124 -0.016 1.70e-05
MultiScler pT+clump.MultiPRS lassosum.MultiPRS 0.114 0.126 -0.012 9.69e-02 0.116 0.124 -0.009 1.30e-01
MultiScler lassosum.MultiPRS lassosum.MultiPRS 0.126 0.126 0.000 1.00e+00 0.124 0.124 0.000 1.00e+00
MultiScler lassosum.PseudoVal lassosum.MultiPRS 0.100 0.126 -0.026 2.26e-04 0.106 0.124 -0.019 3.38e-04
MultiScler LDpred2.MultiPRS lassosum.MultiPRS 0.130 0.126 0.004 1.20e-01 0.117 0.124 -0.007 1.25e-01
MultiScler LDpred1.MultiPRS lassosum.MultiPRS 0.103 0.126 -0.023 1.99e-14 0.096 0.124 -0.028 1.65e-06
MultiScler LDpred2.PseudoVal lassosum.MultiPRS 0.101 0.126 -0.025 3.72e-04 0.088 0.124 -0.036 9.10e-07
MultiScler LDpred1.Inf lassosum.MultiPRS 0.089 0.126 -0.037 1.03e-07 0.081 0.124 -0.044 6.13e-09
MultiScler pT+clump.10FCVal lassosum.MultiPRS 0.090 0.126 -0.036 3.50e-07 0.092 0.124 -0.033 3.14e-04
MultiScler lassosum.10FCVal lassosum.MultiPRS 0.115 0.126 -0.011 1.24e-01 0.102 0.124 -0.022 1.99e-06
MultiScler SBLUP.Inf lassosum.MultiPRS 0.093 0.126 -0.033 2.37e-06 0.079 0.124 -0.045 3.28e-08
MultiScler DBSLMM.PseudoVal lassosum.MultiPRS 0.090 0.126 -0.036 2.94e-07 0.085 0.124 -0.040 2.57e-07
MultiScler All.MultiPRS lassosum.MultiPRS 0.133 0.126 0.007 2.93e-04 0.121 0.124 -0.003 4.05e-01
MultiScler PRScs.PseudoVal lassosum.MultiPRS 0.103 0.126 -0.023 1.11e-03 0.101 0.124 -0.023 9.43e-06
MultiScler LDpred1.Inf lassosum.PseudoVal 0.089 0.100 -0.012 1.63e-02 0.081 0.106 -0.025 9.08e-03
MultiScler PRScs.10FCVal lassosum.PseudoVal 0.118 0.100 0.017 3.41e-05 0.104 0.106 -0.002 8.12e-01
MultiScler LDpred2.MultiPRS lassosum.PseudoVal 0.130 0.100 0.030 2.34e-05 0.117 0.106 0.011 1.10e-01
MultiScler lassosum.PseudoVal lassosum.PseudoVal 0.100 0.100 0.000 1.00e+00 0.106 0.106 0.000 1.00e+00
MultiScler PRScs.PseudoVal lassosum.PseudoVal 0.103 0.100 0.003 9.12e-02 0.101 0.106 -0.004 1.99e-01
MultiScler DBSLMM.PseudoVal lassosum.PseudoVal 0.090 0.100 -0.010 1.26e-05 0.085 0.106 -0.021 1.02e-05
MultiScler SBLUP.Inf lassosum.PseudoVal 0.093 0.100 -0.007 2.03e-01 0.079 0.106 -0.027 2.03e-02
MultiScler LDpred2.Inf lassosum.PseudoVal 0.092 0.100 -0.008 1.57e-01 0.078 0.106 -0.027 1.88e-02
MultiScler pT+clump.10FCVal lassosum.PseudoVal 0.090 0.100 -0.010 1.75e-02 0.092 0.106 -0.014 9.87e-02
MultiScler LDpred2.10FCVal lassosum.PseudoVal 0.112 0.100 0.012 5.34e-06 0.101 0.106 -0.005 3.48e-01
MultiScler lassosum.MultiPRS lassosum.PseudoVal 0.126 0.100 0.026 2.26e-04 0.124 0.106 0.019 3.38e-04
MultiScler LDpred1.10FCVal lassosum.PseudoVal 0.103 0.100 0.003 3.97e-01 0.095 0.106 -0.011 7.21e-02
MultiScler All.MultiPRS lassosum.PseudoVal 0.133 0.100 0.033 2.34e-06 0.121 0.106 0.015 2.27e-02
MultiScler SBayesR.PseudoVal lassosum.PseudoVal 0.100 0.100 -0.001 9.27e-01 0.084 0.106 -0.022 5.37e-02
MultiScler lassosum.10FCVal lassosum.PseudoVal 0.115 0.100 0.015 1.19e-04 0.102 0.106 -0.004 6.45e-01
MultiScler pT+clump.MultiPRS lassosum.PseudoVal 0.114 0.100 0.014 4.24e-02 0.116 0.106 0.010 2.05e-01
MultiScler LDpred2.PseudoVal lassosum.PseudoVal 0.101 0.100 0.001 8.77e-01 0.088 0.106 -0.018 1.01e-01
MultiScler LDpred1.MultiPRS lassosum.PseudoVal 0.103 0.100 0.003 7.10e-01 0.096 0.106 -0.010 1.26e-01
MultiScler PRScs.MultiPRS lassosum.PseudoVal 0.118 0.100 0.018 9.90e-03 0.108 0.106 0.002 6.47e-01
MultiScler lassosum.10FCVal lassosum.10FCVal 0.115 0.115 0.000 1.00e+00 0.102 0.102 0.000 1.00e+00
MultiScler pT+clump.MultiPRS lassosum.10FCVal 0.114 0.115 -0.001 9.05e-01 0.116 0.102 0.014 6.52e-02
MultiScler LDpred2.Inf lassosum.10FCVal 0.092 0.115 -0.023 5.11e-11 0.078 0.102 -0.024 8.32e-04
MultiScler SBayesR.PseudoVal lassosum.10FCVal 0.100 0.115 -0.016 1.35e-03 0.084 0.102 -0.018 5.88e-02
MultiScler PRScs.MultiPRS lassosum.10FCVal 0.118 0.115 0.003 6.66e-01 0.108 0.102 0.006 2.50e-01
MultiScler SBLUP.Inf lassosum.10FCVal 0.093 0.115 -0.022 1.71e-10 0.079 0.102 -0.023 9.70e-04
MultiScler lassosum.MultiPRS lassosum.10FCVal 0.126 0.115 0.011 1.24e-01 0.124 0.102 0.022 1.99e-06
MultiScler PRScs.10FCVal lassosum.10FCVal 0.118 0.115 0.002 2.18e-01 0.104 0.102 0.002 6.91e-01
MultiScler LDpred2.MultiPRS lassosum.10FCVal 0.130 0.115 0.015 3.75e-02 0.117 0.102 0.015 2.62e-02
MultiScler PRScs.PseudoVal lassosum.10FCVal 0.103 0.115 -0.012 1.19e-03 0.101 0.102 -0.001 9.09e-01
MultiScler LDpred2.PseudoVal lassosum.10FCVal 0.101 0.115 -0.014 5.11e-06 0.088 0.102 -0.014 2.54e-02
MultiScler LDpred1.MultiPRS lassosum.10FCVal 0.103 0.115 -0.012 7.70e-02 0.096 0.102 -0.006 3.93e-01
MultiScler pT+clump.10FCVal lassosum.10FCVal 0.090 0.115 -0.025 5.56e-06 0.092 0.102 -0.011 3.44e-01
MultiScler All.MultiPRS lassosum.10FCVal 0.133 0.115 0.018 1.01e-02 0.121 0.102 0.019 2.67e-03
MultiScler LDpred1.Inf lassosum.10FCVal 0.089 0.115 -0.027 1.75e-13 0.081 0.102 -0.021 2.99e-03
MultiScler DBSLMM.PseudoVal lassosum.10FCVal 0.090 0.115 -0.025 3.61e-07 0.085 0.102 -0.017 7.84e-02
MultiScler LDpred1.10FCVal lassosum.10FCVal 0.103 0.115 -0.012 3.88e-04 0.095 0.102 -0.007 2.99e-01
MultiScler lassosum.PseudoVal lassosum.10FCVal 0.100 0.115 -0.015 1.19e-04 0.106 0.102 0.004 6.45e-01
MultiScler LDpred2.10FCVal lassosum.10FCVal 0.112 0.115 -0.003 4.52e-01 0.101 0.102 -0.001 9.02e-01
MultiScler LDpred2.10FCVal LDpred1.MultiPRS 0.112 0.103 0.009 1.97e-01 0.101 0.096 0.005 4.71e-01
MultiScler PRScs.PseudoVal LDpred1.MultiPRS 0.103 0.103 0.000 9.63e-01 0.101 0.096 0.005 3.37e-01
MultiScler LDpred2.Inf LDpred1.MultiPRS 0.092 0.103 -0.011 1.23e-01 0.078 0.096 -0.018 5.93e-02
MultiScler pT+clump.10FCVal LDpred1.MultiPRS 0.090 0.103 -0.013 7.51e-02 0.092 0.096 -0.005 6.48e-01
MultiScler SBayesR.PseudoVal LDpred1.MultiPRS 0.100 0.103 -0.003 6.55e-01 0.084 0.096 -0.012 2.59e-01
MultiScler All.MultiPRS LDpred1.MultiPRS 0.133 0.103 0.030 1.34e-19 0.121 0.096 0.025 1.32e-04
MultiScler LDpred1.10FCVal LDpred1.MultiPRS 0.103 0.103 0.000 9.94e-01 0.095 0.096 -0.001 4.87e-01
MultiScler LDpred1.MultiPRS LDpred1.MultiPRS 0.103 0.103 0.000 1.00e+00 0.096 0.096 0.000 1.00e+00
MultiScler PRScs.10FCVal LDpred1.MultiPRS 0.118 0.103 0.015 3.41e-02 0.104 0.096 0.008 2.57e-01
MultiScler lassosum.PseudoVal LDpred1.MultiPRS 0.100 0.103 -0.003 7.10e-01 0.106 0.096 0.010 1.26e-01
MultiScler pT+clump.MultiPRS LDpred1.MultiPRS 0.114 0.103 0.012 9.81e-02 0.116 0.096 0.019 1.80e-02
MultiScler LDpred1.Inf LDpred1.MultiPRS 0.089 0.103 -0.014 4.37e-02 0.081 0.096 -0.016 3.80e-03
MultiScler lassosum.MultiPRS LDpred1.MultiPRS 0.126 0.103 0.023 1.99e-14 0.124 0.096 0.028 1.65e-06
MultiScler PRScs.MultiPRS LDpred1.MultiPRS 0.118 0.103 0.015 9.87e-10 0.108 0.096 0.012 1.43e-02
MultiScler lassosum.10FCVal LDpred1.MultiPRS 0.115 0.103 0.012 7.70e-02 0.102 0.096 0.006 3.93e-01
MultiScler LDpred2.PseudoVal LDpred1.MultiPRS 0.101 0.103 -0.002 7.99e-01 0.088 0.096 -0.008 3.44e-01
MultiScler DBSLMM.PseudoVal LDpred1.MultiPRS 0.090 0.103 -0.013 6.98e-02 0.085 0.096 -0.011 1.24e-01
MultiScler LDpred2.MultiPRS LDpred1.MultiPRS 0.130 0.103 0.027 6.54e-16 0.117 0.096 0.021 1.14e-03
MultiScler SBLUP.Inf LDpred1.MultiPRS 0.093 0.103 -0.010 1.57e-01 0.079 0.096 -0.017 6.52e-02
MultiScler All.MultiPRS LDpred1.Inf 0.133 0.089 0.045 2.09e-10 0.121 0.081 0.040 7.74e-07
MultiScler LDpred2.PseudoVal LDpred1.Inf 0.101 0.089 0.012 1.53e-04 0.088 0.081 0.008 2.53e-01
MultiScler SBayesR.PseudoVal LDpred1.Inf 0.100 0.089 0.011 3.06e-02 0.084 0.081 0.003 7.59e-01
MultiScler LDpred2.MultiPRS LDpred1.Inf 0.130 0.089 0.041 4.49e-09 0.117 0.081 0.036 5.01e-06
MultiScler PRScs.PseudoVal LDpred1.Inf 0.103 0.089 0.015 8.65e-04 0.101 0.081 0.021 1.73e-02
MultiScler LDpred1.Inf LDpred1.Inf 0.089 0.089 0.000 1.00e+00 0.081 0.081 0.000 1.00e+00
MultiScler pT+clump.10FCVal LDpred1.Inf 0.090 0.089 0.002 7.76e-01 0.092 0.081 0.011 3.58e-01
MultiScler PRScs.MultiPRS LDpred1.Inf 0.118 0.089 0.030 2.45e-05 0.108 0.081 0.027 1.37e-04
MultiScler lassosum.PseudoVal LDpred1.Inf 0.100 0.089 0.012 1.63e-02 0.106 0.081 0.025 9.08e-03
MultiScler pT+clump.MultiPRS LDpred1.Inf 0.114 0.089 0.026 2.28e-04 0.116 0.081 0.035 1.55e-04
MultiScler LDpred1.MultiPRS LDpred1.Inf 0.103 0.089 0.014 4.37e-02 0.096 0.081 0.016 3.80e-03
MultiScler PRScs.10FCVal LDpred1.Inf 0.118 0.089 0.029 3.77e-19 0.104 0.081 0.023 3.46e-04
MultiScler LDpred2.Inf LDpred1.Inf 0.092 0.089 0.003 3.45e-01 0.078 0.081 -0.002 7.47e-01
MultiScler SBLUP.Inf LDpred1.Inf 0.093 0.089 0.004 2.29e-01 0.079 0.081 -0.002 8.05e-01
MultiScler DBSLMM.PseudoVal LDpred1.Inf 0.090 0.089 0.001 7.87e-01 0.085 0.081 0.004 7.01e-01
MultiScler lassosum.MultiPRS LDpred1.Inf 0.126 0.089 0.037 1.03e-07 0.124 0.081 0.044 6.13e-09
MultiScler LDpred1.10FCVal LDpred1.Inf 0.103 0.089 0.014 1.11e-07 0.095 0.081 0.014 7.42e-03
MultiScler lassosum.10FCVal LDpred1.Inf 0.115 0.089 0.027 1.75e-13 0.102 0.081 0.021 2.99e-03
MultiScler LDpred2.10FCVal LDpred1.Inf 0.112 0.089 0.023 3.29e-06 0.101 0.081 0.020 3.93e-02
MultiScler LDpred1.Inf LDpred1.10FCVal 0.089 0.103 -0.014 1.11e-07 0.081 0.095 -0.014 7.42e-03
MultiScler PRScs.MultiPRS LDpred1.10FCVal 0.118 0.103 0.015 2.73e-02 0.108 0.095 0.013 3.72e-03
MultiScler LDpred1.10FCVal LDpred1.10FCVal 0.103 0.103 0.000 1.00e+00 0.095 0.095 0.000 1.00e+00
MultiScler All.MultiPRS LDpred1.10FCVal 0.133 0.103 0.030 1.40e-05 0.121 0.095 0.026 6.90e-05
MultiScler SBayesR.PseudoVal LDpred1.10FCVal 0.100 0.103 -0.003 5.77e-01 0.084 0.095 -0.011 3.17e-01
MultiScler DBSLMM.PseudoVal LDpred1.10FCVal 0.090 0.103 -0.013 3.38e-04 0.085 0.095 -0.010 1.53e-01
MultiScler pT+clump.MultiPRS LDpred1.10FCVal 0.114 0.103 0.012 9.58e-02 0.116 0.095 0.021 1.16e-02
MultiScler lassosum.MultiPRS LDpred1.10FCVal 0.126 0.103 0.023 9.32e-04 0.124 0.095 0.029 3.53e-07
MultiScler PRScs.10FCVal LDpred1.10FCVal 0.118 0.103 0.015 1.07e-05 0.104 0.095 0.009 1.83e-01
MultiScler lassosum.10FCVal LDpred1.10FCVal 0.115 0.103 0.012 3.88e-04 0.102 0.095 0.007 2.99e-01
MultiScler SBLUP.Inf LDpred1.10FCVal 0.093 0.103 -0.010 3.65e-02 0.079 0.095 -0.016 9.09e-02
MultiScler LDpred2.PseudoVal LDpred1.10FCVal 0.101 0.103 -0.002 6.85e-01 0.088 0.095 -0.007 4.29e-01
MultiScler pT+clump.10FCVal LDpred1.10FCVal 0.090 0.103 -0.012 1.02e-02 0.092 0.095 -0.003 7.38e-01
MultiScler LDpred2.MultiPRS LDpred1.10FCVal 0.130 0.103 0.027 1.16e-04 0.117 0.095 0.022 6.29e-04
MultiScler PRScs.PseudoVal LDpred1.10FCVal 0.103 0.103 0.000 8.82e-01 0.101 0.095 0.006 1.97e-01
MultiScler LDpred2.10FCVal LDpred1.10FCVal 0.112 0.103 0.009 7.45e-03 0.101 0.095 0.006 3.58e-01
MultiScler LDpred1.MultiPRS LDpred1.10FCVal 0.103 0.103 0.000 9.94e-01 0.096 0.095 0.001 4.87e-01
MultiScler LDpred2.Inf LDpred1.10FCVal 0.092 0.103 -0.011 2.39e-02 0.078 0.095 -0.017 8.30e-02
MultiScler lassosum.PseudoVal LDpred1.10FCVal 0.100 0.103 -0.003 3.97e-01 0.106 0.095 0.011 7.21e-02
MultiScler LDpred1.Inf LDpred2.MultiPRS 0.089 0.130 -0.041 4.49e-09 0.081 0.117 -0.036 5.01e-06
MultiScler DBSLMM.PseudoVal LDpred2.MultiPRS 0.090 0.130 -0.040 1.40e-08 0.085 0.117 -0.032 1.71e-04
MultiScler SBLUP.Inf LDpred2.MultiPRS 0.093 0.130 -0.037 1.38e-07 0.079 0.117 -0.038 7.07e-06
MultiScler LDpred2.Inf LDpred2.MultiPRS 0.092 0.130 -0.038 6.85e-08 0.078 0.117 -0.039 6.03e-06
MultiScler pT+clump.10FCVal LDpred2.MultiPRS 0.090 0.130 -0.040 1.67e-08 0.092 0.117 -0.025 6.11e-03
MultiScler LDpred2.10FCVal LDpred2.MultiPRS 0.112 0.130 -0.018 1.02e-02 0.101 0.117 -0.016 1.06e-03
MultiScler PRScs.PseudoVal LDpred2.MultiPRS 0.103 0.130 -0.027 1.41e-04 0.101 0.117 -0.016 1.94e-02
MultiScler LDpred1.10FCVal LDpred2.MultiPRS 0.103 0.130 -0.027 1.16e-04 0.095 0.117 -0.022 6.29e-04
MultiScler All.MultiPRS LDpred2.MultiPRS 0.133 0.130 0.003 8.80e-03 0.121 0.117 0.004 1.26e-01
MultiScler SBayesR.PseudoVal LDpred2.MultiPRS 0.100 0.130 -0.030 1.59e-05 0.084 0.117 -0.033 9.98e-05
MultiScler lassosum.10FCVal LDpred2.MultiPRS 0.115 0.130 -0.015 3.75e-02 0.102 0.117 -0.015 2.62e-02
MultiScler pT+clump.MultiPRS LDpred2.MultiPRS 0.114 0.130 -0.015 2.76e-02 0.116 0.117 -0.001 8.38e-01
MultiScler lassosum.MultiPRS LDpred2.MultiPRS 0.126 0.130 -0.004 1.20e-01 0.124 0.117 0.007 1.25e-01
MultiScler PRScs.10FCVal LDpred2.MultiPRS 0.118 0.130 -0.012 8.38e-02 0.104 0.117 -0.013 4.68e-02
MultiScler PRScs.MultiPRS LDpred2.MultiPRS 0.118 0.130 -0.012 1.14e-04 0.108 0.117 -0.009 1.24e-01
MultiScler lassosum.PseudoVal LDpred2.MultiPRS 0.100 0.130 -0.030 2.34e-05 0.106 0.117 -0.011 1.10e-01
MultiScler LDpred2.PseudoVal LDpred2.MultiPRS 0.101 0.130 -0.029 4.02e-05 0.088 0.117 -0.029 1.63e-04
MultiScler LDpred1.MultiPRS LDpred2.MultiPRS 0.103 0.130 -0.027 6.54e-16 0.096 0.117 -0.021 1.14e-03
MultiScler LDpred2.MultiPRS LDpred2.MultiPRS 0.130 0.130 0.000 1.00e+00 0.117 0.117 0.000 1.00e+00
MultiScler LDpred1.Inf LDpred2.10FCVal 0.089 0.112 -0.023 3.29e-06 0.081 0.101 -0.020 3.93e-02
MultiScler PRScs.MultiPRS LDpred2.10FCVal 0.118 0.112 0.006 3.60e-01 0.108 0.101 0.007 2.87e-01
MultiScler LDpred2.MultiPRS LDpred2.10FCVal 0.130 0.112 0.018 1.02e-02 0.117 0.101 0.016 1.06e-03
MultiScler PRScs.PseudoVal LDpred2.10FCVal 0.103 0.112 -0.009 1.62e-03 0.101 0.101 0.000 9.66e-01
MultiScler LDpred2.10FCVal LDpred2.10FCVal 0.112 0.112 0.000 1.00e+00 0.101 0.101 0.000 1.00e+00
MultiScler lassosum.MultiPRS LDpred2.10FCVal 0.126 0.112 0.014 4.28e-02 0.124 0.101 0.023 2.36e-04
MultiScler LDpred1.10FCVal LDpred2.10FCVal 0.103 0.112 -0.009 7.45e-03 0.095 0.101 -0.006 3.58e-01
MultiScler All.MultiPRS LDpred2.10FCVal 0.133 0.112 0.021 2.19e-03 0.121 0.101 0.020 2.34e-04
MultiScler SBayesR.PseudoVal LDpred2.10FCVal 0.100 0.112 -0.012 1.79e-02 0.084 0.101 -0.017 9.64e-02
MultiScler DBSLMM.PseudoVal LDpred2.10FCVal 0.090 0.112 -0.022 1.69e-13 0.085 0.101 -0.016 6.56e-03
MultiScler pT+clump.MultiPRS LDpred2.10FCVal 0.114 0.112 0.003 7.16e-01 0.116 0.101 0.015 7.21e-02
MultiScler lassosum.PseudoVal LDpred2.10FCVal 0.100 0.112 -0.012 5.34e-06 0.106 0.101 0.005 3.48e-01
MultiScler PRScs.10FCVal LDpred2.10FCVal 0.118 0.112 0.006 2.13e-01 0.104 0.101 0.003 7.70e-01
MultiScler lassosum.10FCVal LDpred2.10FCVal 0.115 0.112 0.003 4.52e-01 0.102 0.101 0.001 9.02e-01
MultiScler SBLUP.Inf LDpred2.10FCVal 0.093 0.112 -0.019 1.17e-03 0.079 0.101 -0.022 5.85e-02
MultiScler LDpred2.PseudoVal LDpred2.10FCVal 0.101 0.112 -0.011 4.67e-02 0.088 0.101 -0.013 2.36e-01
MultiScler pT+clump.10FCVal LDpred2.10FCVal 0.090 0.112 -0.022 3.00e-08 0.092 0.101 -0.009 2.45e-01
MultiScler LDpred2.Inf LDpred2.10FCVal 0.092 0.112 -0.020 7.23e-04 0.078 0.101 -0.023 5.37e-02
MultiScler LDpred1.MultiPRS LDpred2.10FCVal 0.103 0.112 -0.009 1.97e-01 0.096 0.101 -0.005 4.71e-01
MultiScler lassosum.10FCVal LDpred2.PseudoVal 0.115 0.101 0.014 5.11e-06 0.102 0.088 0.014 2.54e-02
MultiScler SBLUP.Inf LDpred2.PseudoVal 0.093 0.101 -0.008 4.96e-30 0.079 0.088 -0.009 1.32e-10
MultiScler SBayesR.PseudoVal LDpred2.PseudoVal 0.100 0.101 -0.001 7.85e-01 0.084 0.088 -0.004 6.59e-01
MultiScler All.MultiPRS LDpred2.PseudoVal 0.133 0.101 0.032 4.28e-06 0.121 0.088 0.033 4.34e-05
MultiScler PRScs.PseudoVal LDpred2.PseudoVal 0.103 0.101 0.002 6.63e-01 0.101 0.088 0.013 1.77e-01
MultiScler lassosum.MultiPRS LDpred2.PseudoVal 0.126 0.101 0.025 3.72e-04 0.124 0.088 0.036 9.10e-07
MultiScler PRScs.MultiPRS LDpred2.PseudoVal 0.118 0.101 0.017 1.41e-02 0.108 0.088 0.020 7.88e-03
MultiScler LDpred2.MultiPRS LDpred2.PseudoVal 0.130 0.101 0.029 4.02e-05 0.117 0.088 0.029 1.63e-04
MultiScler PRScs.10FCVal LDpred2.PseudoVal 0.118 0.101 0.017 6.94e-12 0.104 0.088 0.016 1.52e-03
MultiScler LDpred2.PseudoVal LDpred2.PseudoVal 0.101 0.101 0.000 1.00e+00 0.088 0.088 0.000 1.00e+00
MultiScler pT+clump.MultiPRS LDpred2.PseudoVal 0.114 0.101 0.013 5.58e-02 0.116 0.088 0.027 2.40e-03
MultiScler pT+clump.10FCVal LDpred2.PseudoVal 0.090 0.101 -0.011 8.27e-02 0.092 0.088 0.003 7.84e-01
MultiScler lassosum.PseudoVal LDpred2.PseudoVal 0.100 0.101 -0.001 8.77e-01 0.106 0.088 0.018 1.01e-01
MultiScler LDpred1.Inf LDpred2.PseudoVal 0.089 0.101 -0.012 1.53e-04 0.081 0.088 -0.008 2.53e-01
MultiScler LDpred1.MultiPRS LDpred2.PseudoVal 0.103 0.101 0.002 7.99e-01 0.096 0.088 0.008 3.44e-01
MultiScler LDpred1.10FCVal LDpred2.PseudoVal 0.103 0.101 0.002 6.85e-01 0.095 0.088 0.007 4.29e-01
MultiScler LDpred2.Inf LDpred2.PseudoVal 0.092 0.101 -0.009 4.19e-33 0.078 0.088 -0.010 9.82e-11
MultiScler LDpred2.10FCVal LDpred2.PseudoVal 0.112 0.101 0.011 4.67e-02 0.101 0.088 0.013 2.36e-01
MultiScler DBSLMM.PseudoVal LDpred2.PseudoVal 0.090 0.101 -0.011 6.67e-02 0.085 0.088 -0.003 7.77e-01
MultiScler pT+clump.MultiPRS LDpred2.Inf 0.114 0.092 0.022 1.36e-03 0.116 0.078 0.037 9.97e-05
MultiScler lassosum.MultiPRS LDpred2.Inf 0.126 0.092 0.034 1.26e-06 0.124 0.078 0.046 3.23e-08
MultiScler SBayesR.PseudoVal LDpred2.Inf 0.100 0.092 0.008 1.17e-01 0.084 0.078 0.005 5.81e-01
MultiScler All.MultiPRS LDpred2.Inf 0.133 0.092 0.041 3.97e-09 0.121 0.078 0.043 1.43e-06
MultiScler SBLUP.Inf LDpred2.Inf 0.093 0.092 0.001 3.83e-13 0.079 0.078 0.001 2.41e-02
MultiScler LDpred2.PseudoVal LDpred2.Inf 0.101 0.092 0.009 4.19e-33 0.088 0.078 0.010 9.82e-11
MultiScler PRScs.MultiPRS LDpred2.Inf 0.118 0.092 0.026 1.83e-04 0.108 0.078 0.030 5.67e-04
MultiScler LDpred2.MultiPRS LDpred2.Inf 0.130 0.092 0.038 6.85e-08 0.117 0.078 0.039 6.03e-06
MultiScler PRScs.10FCVal LDpred2.Inf 0.118 0.092 0.026 9.94e-19 0.104 0.078 0.025 1.63e-05
MultiScler LDpred1.Inf LDpred2.Inf 0.089 0.092 -0.003 3.45e-01 0.081 0.078 0.002 7.47e-01
MultiScler LDpred1.MultiPRS LDpred2.Inf 0.103 0.092 0.011 1.23e-01 0.096 0.078 0.018 5.93e-02
MultiScler pT+clump.10FCVal LDpred2.Inf 0.090 0.092 -0.002 7.92e-01 0.092 0.078 0.013 3.10e-01
MultiScler lassosum.PseudoVal LDpred2.Inf 0.100 0.092 0.008 1.57e-01 0.106 0.078 0.027 1.88e-02
MultiScler PRScs.PseudoVal LDpred2.Inf 0.103 0.092 0.011 3.72e-02 0.101 0.078 0.023 3.27e-02
MultiScler DBSLMM.PseudoVal LDpred2.Inf 0.090 0.092 -0.002 7.64e-01 0.085 0.078 0.006 6.18e-01
MultiScler LDpred1.10FCVal LDpred2.Inf 0.103 0.092 0.011 2.39e-02 0.095 0.078 0.017 8.30e-02
MultiScler LDpred2.Inf LDpred2.Inf 0.092 0.092 0.000 1.00e+00 0.078 0.078 0.000 1.00e+00
MultiScler lassosum.10FCVal LDpred2.Inf 0.115 0.092 0.023 5.11e-11 0.102 0.078 0.024 8.32e-04
MultiScler LDpred2.10FCVal LDpred2.Inf 0.112 0.092 0.020 7.23e-04 0.101 0.078 0.023 5.37e-02
MultiScler PRScs.10FCVal PRScs.MultiPRS 0.118 0.118 -0.001 9.35e-01 0.104 0.108 -0.004 3.15e-01
MultiScler LDpred1.10FCVal PRScs.MultiPRS 0.103 0.118 -0.015 2.73e-02 0.095 0.108 -0.013 3.72e-03
MultiScler lassosum.MultiPRS PRScs.MultiPRS 0.126 0.118 0.008 4.13e-05 0.124 0.108 0.016 1.70e-05
MultiScler LDpred2.MultiPRS PRScs.MultiPRS 0.130 0.118 0.012 1.14e-04 0.117 0.108 0.009 1.24e-01
MultiScler All.MultiPRS PRScs.MultiPRS 0.133 0.118 0.015 7.83e-08 0.121 0.108 0.013 1.71e-02
MultiScler PRScs.PseudoVal PRScs.MultiPRS 0.103 0.118 -0.015 3.11e-02 0.101 0.108 -0.007 5.56e-02
MultiScler LDpred1.MultiPRS PRScs.MultiPRS 0.103 0.118 -0.015 9.87e-10 0.096 0.108 -0.012 1.43e-02
MultiScler pT+clump.MultiPRS PRScs.MultiPRS 0.114 0.118 -0.004 5.82e-01 0.116 0.108 0.008 2.68e-01
MultiScler lassosum.PseudoVal PRScs.MultiPRS 0.100 0.118 -0.018 9.90e-03 0.106 0.108 -0.002 6.47e-01
MultiScler SBayesR.PseudoVal PRScs.MultiPRS 0.100 0.118 -0.019 7.82e-03 0.084 0.108 -0.024 2.42e-02
MultiScler DBSLMM.PseudoVal PRScs.MultiPRS 0.090 0.118 -0.028 5.80e-05 0.085 0.108 -0.023 4.38e-04
MultiScler SBLUP.Inf PRScs.MultiPRS 0.093 0.118 -0.025 3.00e-04 0.079 0.108 -0.029 6.11e-04
MultiScler LDpred2.Inf PRScs.MultiPRS 0.092 0.118 -0.026 1.83e-04 0.078 0.108 -0.030 5.67e-04
MultiScler pT+clump.10FCVal PRScs.MultiPRS 0.090 0.118 -0.028 6.70e-05 0.092 0.108 -0.016 8.26e-02
MultiScler LDpred2.10FCVal PRScs.MultiPRS 0.112 0.118 -0.006 3.60e-01 0.101 0.108 -0.007 2.87e-01
MultiScler lassosum.10FCVal PRScs.MultiPRS 0.115 0.118 -0.003 6.66e-01 0.102 0.108 -0.006 2.50e-01
MultiScler LDpred2.PseudoVal PRScs.MultiPRS 0.101 0.118 -0.017 1.41e-02 0.088 0.108 -0.020 7.88e-03
MultiScler LDpred1.Inf PRScs.MultiPRS 0.089 0.118 -0.030 2.45e-05 0.081 0.108 -0.027 1.37e-04
MultiScler PRScs.MultiPRS PRScs.MultiPRS 0.118 0.118 0.000 1.00e+00 0.108 0.108 0.000 1.00e+00
MultiScler LDpred2.PseudoVal PRScs.10FCVal 0.101 0.118 -0.017 6.94e-12 0.088 0.104 -0.016 1.52e-03
MultiScler PRScs.10FCVal PRScs.10FCVal 0.118 0.118 0.000 1.00e+00 0.104 0.104 0.000 1.00e+00
MultiScler LDpred2.MultiPRS PRScs.10FCVal 0.130 0.118 0.012 8.38e-02 0.117 0.104 0.013 4.68e-02
MultiScler pT+clump.MultiPRS PRScs.10FCVal 0.114 0.118 -0.003 6.38e-01 0.116 0.104 0.012 1.09e-01
MultiScler LDpred1.Inf PRScs.10FCVal 0.089 0.118 -0.029 3.77e-19 0.081 0.104 -0.023 3.46e-04
MultiScler LDpred1.MultiPRS PRScs.10FCVal 0.103 0.118 -0.015 3.41e-02 0.096 0.104 -0.008 2.57e-01
MultiScler pT+clump.10FCVal PRScs.10FCVal 0.090 0.118 -0.027 8.85e-07 0.092 0.104 -0.012 2.80e-01
MultiScler lassosum.PseudoVal PRScs.10FCVal 0.100 0.118 -0.017 3.41e-05 0.106 0.104 0.002 8.12e-01
MultiScler PRScs.PseudoVal PRScs.10FCVal 0.103 0.118 -0.015 9.11e-05 0.101 0.104 -0.002 7.39e-01
MultiScler DBSLMM.PseudoVal PRScs.10FCVal 0.090 0.118 -0.028 3.09e-08 0.085 0.104 -0.019 5.58e-02
MultiScler SBLUP.Inf PRScs.10FCVal 0.093 0.118 -0.025 4.27e-18 0.079 0.104 -0.025 1.81e-05
MultiScler LDpred2.Inf PRScs.10FCVal 0.092 0.118 -0.026 9.94e-19 0.078 0.104 -0.025 1.63e-05
MultiScler lassosum.10FCVal PRScs.10FCVal 0.115 0.118 -0.002 2.18e-01 0.102 0.104 -0.002 6.91e-01
MultiScler LDpred2.10FCVal PRScs.10FCVal 0.112 0.118 -0.006 2.13e-01 0.101 0.104 -0.003 7.70e-01
MultiScler lassosum.MultiPRS PRScs.10FCVal 0.126 0.118 0.008 2.36e-01 0.124 0.104 0.021 8.05e-05
MultiScler LDpred1.10FCVal PRScs.10FCVal 0.103 0.118 -0.015 1.07e-05 0.095 0.104 -0.009 1.83e-01
MultiScler All.MultiPRS PRScs.10FCVal 0.133 0.118 0.016 2.63e-02 0.121 0.104 0.017 6.52e-03
MultiScler SBayesR.PseudoVal PRScs.10FCVal 0.100 0.118 -0.018 3.42e-04 0.084 0.104 -0.020 4.69e-02
MultiScler PRScs.MultiPRS PRScs.10FCVal 0.118 0.118 0.001 9.35e-01 0.108 0.104 0.004 3.15e-01
MultiScler All.MultiPRS PRScs.PseudoVal 0.133 0.103 0.030 1.73e-05 0.121 0.101 0.020 2.48e-03
MultiScler pT+clump.MultiPRS PRScs.PseudoVal 0.114 0.103 0.011 1.07e-01 0.116 0.101 0.014 6.14e-02
MultiScler LDpred2.PseudoVal PRScs.PseudoVal 0.101 0.103 -0.002 6.63e-01 0.088 0.101 -0.013 1.77e-01
MultiScler SBayesR.PseudoVal PRScs.PseudoVal 0.100 0.103 -0.003 5.50e-01 0.084 0.101 -0.017 1.33e-01
MultiScler LDpred2.MultiPRS PRScs.PseudoVal 0.130 0.103 0.027 1.41e-04 0.117 0.101 0.016 1.94e-02
MultiScler SBLUP.Inf PRScs.PseudoVal 0.093 0.103 -0.010 5.29e-02 0.079 0.101 -0.022 3.54e-02
MultiScler LDpred1.Inf PRScs.PseudoVal 0.089 0.103 -0.015 8.65e-04 0.081 0.101 -0.021 1.73e-02
MultiScler PRScs.10FCVal PRScs.PseudoVal 0.118 0.103 0.015 9.11e-05 0.104 0.101 0.002 7.39e-01
MultiScler LDpred2.Inf PRScs.PseudoVal 0.092 0.103 -0.011 3.72e-02 0.078 0.101 -0.023 3.27e-02
MultiScler PRScs.PseudoVal PRScs.PseudoVal 0.103 0.103 0.000 1.00e+00 0.101 0.101 0.000 1.00e+00
MultiScler LDpred2.10FCVal PRScs.PseudoVal 0.112 0.103 0.009 1.62e-03 0.101 0.101 0.000 9.66e-01
MultiScler pT+clump.10FCVal PRScs.PseudoVal 0.090 0.103 -0.013 2.29e-03 0.092 0.101 -0.010 2.60e-01
MultiScler PRScs.MultiPRS PRScs.PseudoVal 0.118 0.103 0.015 3.11e-02 0.108 0.101 0.007 5.56e-02
MultiScler lassosum.PseudoVal PRScs.PseudoVal 0.100 0.103 -0.003 9.12e-02 0.106 0.101 0.004 1.99e-01
MultiScler lassosum.10FCVal PRScs.PseudoVal 0.115 0.103 0.012 1.19e-03 0.102 0.101 0.001 9.09e-01
MultiScler LDpred1.MultiPRS PRScs.PseudoVal 0.103 0.103 0.000 9.63e-01 0.096 0.101 -0.005 3.37e-01
MultiScler lassosum.MultiPRS PRScs.PseudoVal 0.126 0.103 0.023 1.11e-03 0.124 0.101 0.023 9.43e-06
MultiScler LDpred1.10FCVal PRScs.PseudoVal 0.103 0.103 0.000 8.82e-01 0.095 0.101 -0.006 1.97e-01
MultiScler DBSLMM.PseudoVal PRScs.PseudoVal 0.090 0.103 -0.013 2.44e-09 0.085 0.101 -0.017 1.79e-04
MultiScler All.MultiPRS pT+clump.MultiPRS 0.133 0.114 0.019 6.93e-03 0.121 0.116 0.005 3.17e-01
MultiScler SBayesR.PseudoVal pT+clump.MultiPRS 0.100 0.114 -0.015 3.58e-02 0.084 0.116 -0.032 1.82e-04
MultiScler LDpred1.MultiPRS pT+clump.MultiPRS 0.103 0.114 -0.012 9.81e-02 0.096 0.116 -0.019 1.80e-02
MultiScler pT+clump.MultiPRS pT+clump.MultiPRS 0.114 0.114 0.000 1.00e+00 0.116 0.116 0.000 1.00e+00
MultiScler lassosum.PseudoVal pT+clump.MultiPRS 0.100 0.114 -0.014 4.24e-02 0.106 0.116 -0.010 2.05e-01
MultiScler PRScs.10FCVal pT+clump.MultiPRS 0.118 0.114 0.003 6.38e-01 0.104 0.116 -0.012 1.09e-01
MultiScler DBSLMM.PseudoVal pT+clump.MultiPRS 0.090 0.114 -0.024 5.00e-04 0.085 0.116 -0.031 3.13e-04
MultiScler SBLUP.Inf pT+clump.MultiPRS 0.093 0.114 -0.022 2.09e-03 0.079 0.116 -0.037 1.11e-04
MultiScler LDpred2.Inf pT+clump.MultiPRS 0.092 0.114 -0.022 1.36e-03 0.078 0.116 -0.037 9.97e-05
MultiScler pT+clump.10FCVal pT+clump.MultiPRS 0.090 0.114 -0.024 5.61e-04 0.092 0.116 -0.024 3.30e-04
MultiScler LDpred2.10FCVal pT+clump.MultiPRS 0.112 0.114 -0.003 7.16e-01 0.101 0.116 -0.015 7.21e-02
MultiScler PRScs.PseudoVal pT+clump.MultiPRS 0.103 0.114 -0.011 1.07e-01 0.101 0.116 -0.014 6.14e-02
MultiScler LDpred1.10FCVal pT+clump.MultiPRS 0.103 0.114 -0.012 9.58e-02 0.095 0.116 -0.021 1.16e-02
MultiScler LDpred1.Inf pT+clump.MultiPRS 0.089 0.114 -0.026 2.28e-04 0.081 0.116 -0.035 1.55e-04
MultiScler PRScs.MultiPRS pT+clump.MultiPRS 0.118 0.114 0.004 5.82e-01 0.108 0.116 -0.008 2.68e-01
MultiScler lassosum.10FCVal pT+clump.MultiPRS 0.115 0.114 0.001 9.05e-01 0.102 0.116 -0.014 6.52e-02
MultiScler LDpred2.PseudoVal pT+clump.MultiPRS 0.101 0.114 -0.013 5.58e-02 0.088 0.116 -0.027 2.40e-03
MultiScler lassosum.MultiPRS pT+clump.MultiPRS 0.126 0.114 0.012 9.69e-02 0.124 0.116 0.009 1.30e-01
MultiScler LDpred2.MultiPRS pT+clump.MultiPRS 0.130 0.114 0.015 2.76e-02 0.117 0.116 0.001 8.38e-01
MultiScler LDpred2.10FCVal pT+clump.10FCVal 0.112 0.090 0.022 3.00e-08 0.101 0.092 0.009 2.45e-01
MultiScler pT+clump.MultiPRS pT+clump.10FCVal 0.114 0.090 0.024 5.61e-04 0.116 0.092 0.024 3.30e-04
MultiScler LDpred2.Inf pT+clump.10FCVal 0.092 0.090 0.002 7.92e-01 0.078 0.092 -0.013 3.10e-01
MultiScler SBayesR.PseudoVal pT+clump.10FCVal 0.100 0.090 0.009 6.97e-02 0.084 0.092 -0.008 4.68e-01
MultiScler PRScs.MultiPRS pT+clump.10FCVal 0.118 0.090 0.028 6.70e-05 0.108 0.092 0.016 8.26e-02
MultiScler SBLUP.Inf pT+clump.10FCVal 0.093 0.090 0.003 6.86e-01 0.079 0.092 -0.013 3.28e-01
MultiScler lassosum.MultiPRS pT+clump.10FCVal 0.126 0.090 0.036 3.50e-07 0.124 0.092 0.033 3.14e-04
MultiScler PRScs.10FCVal pT+clump.10FCVal 0.118 0.090 0.027 8.85e-07 0.104 0.092 0.012 2.80e-01
MultiScler LDpred2.MultiPRS pT+clump.10FCVal 0.130 0.090 0.040 1.67e-08 0.117 0.092 0.025 6.11e-03
MultiScler lassosum.10FCVal pT+clump.10FCVal 0.115 0.090 0.025 5.56e-06 0.102 0.092 0.011 3.44e-01
MultiScler LDpred2.PseudoVal pT+clump.10FCVal 0.101 0.090 0.011 8.27e-02 0.088 0.092 -0.003 7.84e-01
MultiScler LDpred1.MultiPRS pT+clump.10FCVal 0.103 0.090 0.013 7.51e-02 0.096 0.092 0.005 6.48e-01
MultiScler pT+clump.10FCVal pT+clump.10FCVal 0.090 0.090 0.000 1.00e+00 0.092 0.092 0.000 1.00e+00
MultiScler All.MultiPRS pT+clump.10FCVal 0.133 0.090 0.043 8.56e-10 0.121 0.092 0.029 4.14e-04
MultiScler LDpred1.Inf pT+clump.10FCVal 0.089 0.090 -0.002 7.76e-01 0.081 0.092 -0.011 3.58e-01
MultiScler DBSLMM.PseudoVal pT+clump.10FCVal 0.090 0.090 0.000 9.47e-01 0.085 0.092 -0.007 3.21e-01
MultiScler LDpred1.10FCVal pT+clump.10FCVal 0.103 0.090 0.012 1.02e-02 0.095 0.092 0.003 7.38e-01
MultiScler lassosum.PseudoVal pT+clump.10FCVal 0.100 0.090 0.010 1.75e-02 0.106 0.092 0.014 9.87e-02
MultiScler PRScs.PseudoVal pT+clump.10FCVal 0.103 0.090 0.013 2.29e-03 0.101 0.092 0.010 2.60e-01
MultiScler pT+clump.MultiPRS SBayesR.PseudoVal 0.114 0.100 0.015 3.58e-02 0.116 0.084 0.032 1.82e-04
MultiScler LDpred1.10FCVal SBayesR.PseudoVal 0.103 0.100 0.003 5.77e-01 0.095 0.084 0.011 3.17e-01
MultiScler PRScs.10FCVal SBayesR.PseudoVal 0.118 0.100 0.018 3.42e-04 0.104 0.084 0.020 4.69e-02
MultiScler LDpred2.10FCVal SBayesR.PseudoVal 0.112 0.100 0.012 1.79e-02 0.101 0.084 0.017 9.64e-02
MultiScler lassosum.10FCVal SBayesR.PseudoVal 0.115 0.100 0.016 1.35e-03 0.102 0.084 0.018 5.88e-02
MultiScler LDpred2.PseudoVal SBayesR.PseudoVal 0.101 0.100 0.001 7.85e-01 0.088 0.084 0.004 6.59e-01
MultiScler lassosum.MultiPRS SBayesR.PseudoVal 0.126 0.100 0.026 1.64e-04 0.124 0.084 0.041 7.10e-06
MultiScler LDpred2.MultiPRS SBayesR.PseudoVal 0.130 0.100 0.030 1.59e-05 0.117 0.084 0.033 9.98e-05
MultiScler All.MultiPRS SBayesR.PseudoVal 0.133 0.100 0.034 1.49e-06 0.121 0.084 0.037 1.99e-06
MultiScler PRScs.PseudoVal SBayesR.PseudoVal 0.103 0.100 0.003 5.50e-01 0.101 0.084 0.017 1.33e-01
MultiScler LDpred1.MultiPRS SBayesR.PseudoVal 0.103 0.100 0.003 6.55e-01 0.096 0.084 0.012 2.59e-01
MultiScler pT+clump.10FCVal SBayesR.PseudoVal 0.090 0.100 -0.009 6.97e-02 0.092 0.084 0.008 4.68e-01
MultiScler lassosum.PseudoVal SBayesR.PseudoVal 0.100 0.100 0.001 9.27e-01 0.106 0.084 0.022 5.37e-02
MultiScler SBayesR.PseudoVal SBayesR.PseudoVal 0.100 0.100 0.000 1.00e+00 0.084 0.084 0.000 1.00e+00
MultiScler DBSLMM.PseudoVal SBayesR.PseudoVal 0.090 0.100 -0.010 1.22e-01 0.085 0.084 0.001 9.40e-01
MultiScler SBLUP.Inf SBayesR.PseudoVal 0.093 0.100 -0.007 1.67e-01 0.079 0.084 -0.005 6.20e-01
MultiScler LDpred2.Inf SBayesR.PseudoVal 0.092 0.100 -0.008 1.17e-01 0.078 0.084 -0.005 5.81e-01
MultiScler LDpred1.Inf SBayesR.PseudoVal 0.089 0.100 -0.011 3.06e-02 0.081 0.084 -0.003 7.59e-01
MultiScler PRScs.MultiPRS SBayesR.PseudoVal 0.118 0.100 0.019 7.82e-03 0.108 0.084 0.024 2.42e-02
MultiScler LDpred2.10FCVal SBLUP.Inf 0.112 0.093 0.019 1.17e-03 0.101 0.079 0.022 5.85e-02
MultiScler PRScs.PseudoVal SBLUP.Inf 0.103 0.093 0.010 5.29e-02 0.101 0.079 0.022 3.54e-02
MultiScler LDpred1.10FCVal SBLUP.Inf 0.103 0.093 0.010 3.65e-02 0.095 0.079 0.016 9.09e-02
MultiScler LDpred2.Inf SBLUP.Inf 0.092 0.093 -0.001 3.83e-13 0.078 0.079 -0.001 2.41e-02
MultiScler SBayesR.PseudoVal SBLUP.Inf 0.100 0.093 0.007 1.67e-01 0.084 0.079 0.005 6.20e-01
MultiScler lassosum.10FCVal SBLUP.Inf 0.115 0.093 0.022 1.71e-10 0.102 0.079 0.023 9.70e-04
MultiScler pT+clump.MultiPRS SBLUP.Inf 0.114 0.093 0.022 2.09e-03 0.116 0.079 0.037 1.11e-04
MultiScler lassosum.MultiPRS SBLUP.Inf 0.126 0.093 0.033 2.37e-06 0.124 0.079 0.045 3.28e-08
MultiScler PRScs.10FCVal SBLUP.Inf 0.118 0.093 0.025 4.27e-18 0.104 0.079 0.025 1.81e-05
MultiScler PRScs.MultiPRS SBLUP.Inf 0.118 0.093 0.025 3.00e-04 0.108 0.079 0.029 6.11e-04
MultiScler LDpred1.MultiPRS SBLUP.Inf 0.103 0.093 0.010 1.57e-01 0.096 0.079 0.017 6.52e-02
MultiScler LDpred2.PseudoVal SBLUP.Inf 0.101 0.093 0.008 4.96e-30 0.088 0.079 0.009 1.32e-10
MultiScler LDpred1.Inf SBLUP.Inf 0.089 0.093 -0.004 2.29e-01 0.081 0.079 0.002 8.05e-01
MultiScler LDpred2.MultiPRS SBLUP.Inf 0.130 0.093 0.037 1.38e-07 0.117 0.079 0.038 7.07e-06
MultiScler All.MultiPRS SBLUP.Inf 0.133 0.093 0.040 8.51e-09 0.121 0.079 0.042 1.61e-06
MultiScler SBLUP.Inf SBLUP.Inf 0.093 0.093 0.000 1.00e+00 0.079 0.079 0.000 1.00e+00
MultiScler DBSLMM.PseudoVal SBLUP.Inf 0.090 0.093 -0.003 6.58e-01 0.085 0.079 0.006 6.47e-01
MultiScler pT+clump.10FCVal SBLUP.Inf 0.090 0.093 -0.003 6.86e-01 0.092 0.079 0.013 3.28e-01
MultiScler lassosum.PseudoVal SBLUP.Inf 0.100 0.093 0.007 2.03e-01 0.106 0.079 0.027 2.03e-02
RheuArth LDpred2.PseudoVal All.MultiPRS 0.091 0.185 -0.094 1.39e-41 0.077 0.161 -0.085 3.01e-19
RheuArth pT+clump.10FCVal All.MultiPRS 0.111 0.185 -0.074 4.10e-26 0.103 0.161 -0.058 4.53e-11
RheuArth LDpred2.MultiPRS All.MultiPRS 0.151 0.185 -0.034 1.71e-32 0.127 0.161 -0.034 3.84e-09
RheuArth PRScs.PseudoVal All.MultiPRS 0.162 0.185 -0.022 1.13e-03 0.129 0.161 -0.032 1.52e-12
RheuArth LDpred1.Inf All.MultiPRS 0.136 0.185 -0.048 2.35e-12 0.111 0.161 -0.050 8.32e-14
RheuArth PRScs.MultiPRS All.MultiPRS 0.166 0.185 -0.019 1.02e-21 0.133 0.161 -0.028 7.09e-12
RheuArth LDpred2.Inf All.MultiPRS 0.085 0.185 -0.100 7.60e-47 0.072 0.161 -0.089 7.28e-20
RheuArth lassosum.10FCVal All.MultiPRS 0.162 0.185 -0.023 7.57e-04 0.130 0.161 -0.032 2.31e-12
RheuArth LDpred2.10FCVal All.MultiPRS 0.151 0.185 -0.034 1.08e-06 0.128 0.161 -0.033 4.06e-08
RheuArth lassosum.MultiPRS All.MultiPRS 0.183 0.185 -0.002 7.54e-01 0.150 0.161 -0.011 9.70e-04
RheuArth LDpred1.10FCVal All.MultiPRS 0.136 0.185 -0.048 2.27e-12 0.112 0.161 -0.050 1.88e-13
RheuArth All.MultiPRS All.MultiPRS 0.185 0.185 0.000 1.00e+00 0.161 0.161 0.000 1.00e+00
RheuArth SBayesR.PseudoVal All.MultiPRS 0.124 0.185 -0.061 2.02e-18 0.119 0.161 -0.042 2.05e-07
RheuArth LDpred1.MultiPRS All.MultiPRS 0.145 0.185 -0.039 4.71e-39 0.119 0.161 -0.042 4.49e-12
RheuArth pT+clump.MultiPRS All.MultiPRS 0.131 0.185 -0.054 1.01e-14 0.124 0.161 -0.037 2.25e-07
RheuArth lassosum.PseudoVal All.MultiPRS 0.114 0.185 -0.070 3.66e-24 0.089 0.161 -0.072 3.27e-17
RheuArth PRScs.10FCVal All.MultiPRS 0.161 0.185 -0.024 6.00e-04 0.128 0.161 -0.034 9.61e-13
RheuArth DBSLMM.PseudoVal All.MultiPRS 0.142 0.185 -0.043 7.64e-10 0.111 0.161 -0.051 3.42e-18
RheuArth SBLUP.Inf All.MultiPRS 0.112 0.185 -0.073 7.80e-26 0.097 0.161 -0.065 8.79e-15
RheuArth SBayesR.PseudoVal DBSLMM.PseudoVal 0.124 0.142 -0.018 7.22e-04 0.119 0.111 0.008 4.44e-01
RheuArth LDpred2.Inf DBSLMM.PseudoVal 0.085 0.142 -0.057 2.08e-22 0.072 0.111 -0.039 1.03e-03
RheuArth pT+clump.10FCVal DBSLMM.PseudoVal 0.111 0.142 -0.031 6.56e-09 0.103 0.111 -0.007 4.95e-01
RheuArth PRScs.10FCVal DBSLMM.PseudoVal 0.161 0.142 0.019 6.05e-19 0.128 0.111 0.017 8.66e-05
RheuArth PRScs.PseudoVal DBSLMM.PseudoVal 0.162 0.142 0.020 2.04e-21 0.129 0.111 0.018 2.45e-05
RheuArth pT+clump.MultiPRS DBSLMM.PseudoVal 0.131 0.142 -0.011 1.13e-01 0.124 0.111 0.013 2.00e-01
RheuArth LDpred1.Inf DBSLMM.PseudoVal 0.136 0.142 -0.006 1.56e-01 0.111 0.111 0.000 9.75e-01
RheuArth lassosum.MultiPRS DBSLMM.PseudoVal 0.183 0.142 0.040 5.92e-09 0.150 0.111 0.039 4.38e-11
RheuArth LDpred2.10FCVal DBSLMM.PseudoVal 0.151 0.142 0.009 1.78e-02 0.128 0.111 0.018 2.01e-02
RheuArth lassosum.10FCVal DBSLMM.PseudoVal 0.162 0.142 0.019 1.48e-12 0.130 0.111 0.019 7.03e-04
RheuArth LDpred1.10FCVal DBSLMM.PseudoVal 0.136 0.142 -0.006 1.60e-01 0.112 0.111 0.001 9.21e-01
RheuArth LDpred1.MultiPRS DBSLMM.PseudoVal 0.145 0.142 0.003 6.47e-01 0.119 0.111 0.008 2.79e-01
RheuArth PRScs.MultiPRS DBSLMM.PseudoVal 0.166 0.142 0.023 7.53e-04 0.133 0.111 0.022 6.67e-06
RheuArth All.MultiPRS DBSLMM.PseudoVal 0.185 0.142 0.043 7.64e-10 0.161 0.111 0.051 3.42e-18
RheuArth LDpred2.PseudoVal DBSLMM.PseudoVal 0.091 0.142 -0.051 5.15e-19 0.077 0.111 -0.034 2.97e-03
RheuArth DBSLMM.PseudoVal DBSLMM.PseudoVal 0.142 0.142 0.000 1.00e+00 0.111 0.111 0.000 1.00e+00
RheuArth LDpred2.MultiPRS DBSLMM.PseudoVal 0.151 0.142 0.009 2.16e-01 0.127 0.111 0.017 3.37e-02
RheuArth lassosum.PseudoVal DBSLMM.PseudoVal 0.114 0.142 -0.028 3.51e-08 0.089 0.111 -0.021 3.52e-02
RheuArth SBLUP.Inf DBSLMM.PseudoVal 0.112 0.142 -0.030 8.95e-09 0.097 0.111 -0.014 1.80e-01
RheuArth SBayesR.PseudoVal lassosum.MultiPRS 0.124 0.183 -0.058 4.17e-17 0.119 0.150 -0.031 4.64e-04
RheuArth LDpred2.10FCVal lassosum.MultiPRS 0.151 0.183 -0.031 5.78e-06 0.128 0.150 -0.022 2.24e-03
RheuArth LDpred1.10FCVal lassosum.MultiPRS 0.136 0.183 -0.046 2.97e-11 0.112 0.150 -0.039 1.72e-08
RheuArth LDpred2.Inf lassosum.MultiPRS 0.085 0.183 -0.098 2.27e-44 0.072 0.150 -0.078 4.72e-15
RheuArth PRScs.10FCVal lassosum.MultiPRS 0.161 0.183 -0.022 1.94e-03 0.128 0.150 -0.022 4.05e-07
RheuArth PRScs.MultiPRS lassosum.MultiPRS 0.166 0.183 -0.017 1.37e-02 0.133 0.150 -0.017 1.07e-05
RheuArth pT+clump.MultiPRS lassosum.MultiPRS 0.131 0.183 -0.051 1.21e-13 0.124 0.150 -0.026 1.26e-03
RheuArth lassosum.MultiPRS lassosum.MultiPRS 0.183 0.183 0.000 1.00e+00 0.150 0.150 0.000 1.00e+00
RheuArth lassosum.PseudoVal lassosum.MultiPRS 0.114 0.183 -0.068 9.32e-23 0.089 0.150 -0.061 2.33e-13
RheuArth LDpred2.MultiPRS lassosum.MultiPRS 0.151 0.183 -0.032 4.42e-06 0.127 0.150 -0.023 1.09e-03
RheuArth LDpred1.MultiPRS lassosum.MultiPRS 0.145 0.183 -0.037 7.83e-08 0.119 0.150 -0.031 7.91e-07
RheuArth LDpred2.PseudoVal lassosum.MultiPRS 0.091 0.183 -0.091 2.73e-39 0.077 0.150 -0.074 3.15e-14
RheuArth LDpred1.Inf lassosum.MultiPRS 0.136 0.183 -0.046 3.03e-11 0.111 0.150 -0.039 9.27e-09
RheuArth pT+clump.10FCVal lassosum.MultiPRS 0.111 0.183 -0.071 7.40e-25 0.103 0.150 -0.047 1.39e-06
RheuArth lassosum.10FCVal lassosum.MultiPRS 0.162 0.183 -0.021 2.35e-03 0.130 0.150 -0.020 1.55e-08
RheuArth SBLUP.Inf lassosum.MultiPRS 0.112 0.183 -0.071 3.93e-24 0.097 0.150 -0.054 2.26e-10
RheuArth DBSLMM.PseudoVal lassosum.MultiPRS 0.142 0.183 -0.040 5.92e-09 0.111 0.150 -0.039 4.38e-11
RheuArth All.MultiPRS lassosum.MultiPRS 0.185 0.183 0.002 7.54e-01 0.161 0.150 0.011 9.70e-04
RheuArth PRScs.PseudoVal lassosum.MultiPRS 0.162 0.183 -0.020 3.47e-03 0.129 0.150 -0.021 7.80e-07
RheuArth LDpred1.Inf lassosum.PseudoVal 0.136 0.114 0.022 2.15e-08 0.111 0.089 0.022 5.69e-03
RheuArth PRScs.10FCVal lassosum.PseudoVal 0.161 0.114 0.047 2.29e-23 0.128 0.089 0.038 4.46e-05
RheuArth LDpred2.MultiPRS lassosum.PseudoVal 0.151 0.114 0.036 1.66e-07 0.127 0.089 0.038 7.30e-05
RheuArth lassosum.PseudoVal lassosum.PseudoVal 0.114 0.114 0.000 1.00e+00 0.089 0.089 0.000 1.00e+00
RheuArth PRScs.PseudoVal lassosum.PseudoVal 0.162 0.114 0.048 4.55e-25 0.129 0.089 0.040 1.94e-05
RheuArth DBSLMM.PseudoVal lassosum.PseudoVal 0.142 0.114 0.028 3.51e-08 0.111 0.089 0.021 3.52e-02
RheuArth SBLUP.Inf lassosum.PseudoVal 0.112 0.114 -0.002 5.39e-01 0.097 0.089 0.007 3.37e-01
RheuArth LDpred2.Inf lassosum.PseudoVal 0.085 0.114 -0.029 1.23e-11 0.072 0.089 -0.017 4.76e-02
RheuArth pT+clump.10FCVal lassosum.PseudoVal 0.111 0.114 -0.003 6.14e-01 0.103 0.089 0.014 2.56e-01
RheuArth LDpred2.10FCVal lassosum.PseudoVal 0.151 0.114 0.037 8.81e-14 0.128 0.089 0.039 9.95e-05
RheuArth lassosum.MultiPRS lassosum.PseudoVal 0.183 0.114 0.068 9.32e-23 0.150 0.089 0.061 2.33e-13
RheuArth LDpred1.10FCVal lassosum.PseudoVal 0.136 0.114 0.022 1.67e-08 0.112 0.089 0.022 4.24e-03
RheuArth All.MultiPRS lassosum.PseudoVal 0.185 0.114 0.070 3.66e-24 0.161 0.089 0.072 3.27e-17
RheuArth SBayesR.PseudoVal lassosum.PseudoVal 0.124 0.114 0.010 4.28e-02 0.119 0.089 0.030 2.34e-03
RheuArth lassosum.10FCVal lassosum.PseudoVal 0.162 0.114 0.047 4.34e-27 0.130 0.089 0.041 4.65e-06
RheuArth pT+clump.MultiPRS lassosum.PseudoVal 0.131 0.114 0.017 1.61e-02 0.124 0.089 0.035 4.18e-04
RheuArth LDpred2.PseudoVal lassosum.PseudoVal 0.091 0.114 -0.023 3.18e-08 0.077 0.089 -0.013 1.32e-01
RheuArth LDpred1.MultiPRS lassosum.PseudoVal 0.145 0.114 0.031 8.34e-06 0.119 0.089 0.030 2.27e-04
RheuArth PRScs.MultiPRS lassosum.PseudoVal 0.166 0.114 0.051 1.80e-13 0.133 0.089 0.044 3.08e-08
RheuArth lassosum.10FCVal lassosum.10FCVal 0.162 0.162 0.000 1.00e+00 0.130 0.130 0.000 1.00e+00
RheuArth pT+clump.MultiPRS lassosum.10FCVal 0.131 0.162 -0.030 1.25e-05 0.124 0.130 -0.006 5.22e-01
RheuArth LDpred2.Inf lassosum.10FCVal 0.085 0.162 -0.076 2.73e-45 0.072 0.130 -0.058 1.31e-07
RheuArth SBayesR.PseudoVal lassosum.10FCVal 0.124 0.162 -0.037 1.17e-13 0.119 0.130 -0.011 2.92e-01
RheuArth PRScs.MultiPRS lassosum.10FCVal 0.166 0.162 0.004 5.61e-01 0.133 0.130 0.003 3.74e-01
RheuArth SBLUP.Inf lassosum.10FCVal 0.112 0.162 -0.050 2.47e-26 0.097 0.130 -0.033 4.26e-04
RheuArth lassosum.MultiPRS lassosum.10FCVal 0.183 0.162 0.021 2.35e-03 0.150 0.130 0.020 1.55e-08
RheuArth PRScs.10FCVal lassosum.10FCVal 0.161 0.162 0.000 8.14e-01 0.128 0.130 -0.002 5.84e-01
RheuArth LDpred2.MultiPRS lassosum.10FCVal 0.151 0.162 -0.011 1.20e-01 0.127 0.130 -0.002 7.25e-01
RheuArth PRScs.PseudoVal lassosum.10FCVal 0.162 0.162 0.001 6.61e-01 0.129 0.130 -0.001 8.17e-01
RheuArth LDpred2.PseudoVal lassosum.10FCVal 0.091 0.162 -0.070 9.12e-41 0.077 0.130 -0.053 5.63e-07
RheuArth LDpred1.MultiPRS lassosum.10FCVal 0.145 0.162 -0.016 1.94e-02 0.119 0.130 -0.011 1.02e-01
RheuArth pT+clump.10FCVal lassosum.10FCVal 0.111 0.162 -0.050 3.22e-22 0.103 0.130 -0.027 1.18e-02
RheuArth All.MultiPRS lassosum.10FCVal 0.185 0.162 0.023 7.57e-04 0.161 0.130 0.032 2.31e-12
RheuArth LDpred1.Inf lassosum.10FCVal 0.136 0.162 -0.025 1.26e-12 0.111 0.130 -0.019 9.06e-03
RheuArth DBSLMM.PseudoVal lassosum.10FCVal 0.142 0.162 -0.019 1.48e-12 0.111 0.130 -0.019 7.03e-04
RheuArth LDpred1.10FCVal lassosum.10FCVal 0.136 0.162 -0.025 3.16e-12 0.112 0.130 -0.018 1.29e-02
RheuArth lassosum.PseudoVal lassosum.10FCVal 0.114 0.162 -0.047 4.34e-27 0.089 0.130 -0.041 4.65e-06
RheuArth LDpred2.10FCVal lassosum.10FCVal 0.151 0.162 -0.010 2.81e-03 0.128 0.130 -0.002 8.33e-01
RheuArth LDpred2.10FCVal LDpred1.MultiPRS 0.151 0.145 0.006 4.04e-01 0.128 0.119 0.009 2.39e-01
RheuArth PRScs.PseudoVal LDpred1.MultiPRS 0.162 0.145 0.017 1.43e-02 0.129 0.119 0.010 9.98e-02
RheuArth LDpred2.Inf LDpred1.MultiPRS 0.085 0.145 -0.060 4.34e-18 0.072 0.119 -0.047 9.38e-09
RheuArth pT+clump.10FCVal LDpred1.MultiPRS 0.111 0.145 -0.034 1.01e-06 0.103 0.119 -0.016 1.69e-01
RheuArth SBayesR.PseudoVal LDpred1.MultiPRS 0.124 0.145 -0.021 2.31e-03 0.119 0.119 0.000 9.95e-01
RheuArth All.MultiPRS LDpred1.MultiPRS 0.185 0.145 0.039 4.71e-39 0.161 0.119 0.042 4.49e-12
RheuArth LDpred1.10FCVal LDpred1.MultiPRS 0.136 0.145 -0.009 1.92e-01 0.112 0.119 -0.007 1.54e-02
RheuArth LDpred1.MultiPRS LDpred1.MultiPRS 0.145 0.145 0.000 1.00e+00 0.119 0.119 0.000 1.00e+00
RheuArth PRScs.10FCVal LDpred1.MultiPRS 0.161 0.145 0.016 2.30e-02 0.128 0.119 0.009 1.62e-01
RheuArth lassosum.PseudoVal LDpred1.MultiPRS 0.114 0.145 -0.031 8.34e-06 0.089 0.119 -0.030 2.27e-04
RheuArth pT+clump.MultiPRS LDpred1.MultiPRS 0.131 0.145 -0.014 4.16e-02 0.124 0.119 0.005 5.93e-01
RheuArth LDpred1.Inf LDpred1.MultiPRS 0.136 0.145 -0.009 1.93e-01 0.111 0.119 -0.008 1.11e-02
RheuArth lassosum.MultiPRS LDpred1.MultiPRS 0.183 0.145 0.037 7.83e-08 0.150 0.119 0.031 7.91e-07
RheuArth PRScs.MultiPRS LDpred1.MultiPRS 0.166 0.145 0.020 4.04e-15 0.133 0.119 0.014 6.35e-03
RheuArth lassosum.10FCVal LDpred1.MultiPRS 0.162 0.145 0.016 1.94e-02 0.130 0.119 0.011 1.02e-01
RheuArth LDpred2.PseudoVal LDpred1.MultiPRS 0.091 0.145 -0.054 5.95e-15 0.077 0.119 -0.042 7.86e-08
RheuArth DBSLMM.PseudoVal LDpred1.MultiPRS 0.142 0.145 -0.003 6.47e-01 0.111 0.119 -0.008 2.79e-01
RheuArth LDpred2.MultiPRS LDpred1.MultiPRS 0.151 0.145 0.005 1.40e-01 0.127 0.119 0.008 2.68e-01
RheuArth SBLUP.Inf LDpred1.MultiPRS 0.112 0.145 -0.033 1.54e-06 0.097 0.119 -0.022 5.58e-04
RheuArth All.MultiPRS LDpred1.Inf 0.185 0.136 0.048 2.35e-12 0.161 0.111 0.050 8.32e-14
RheuArth LDpred2.PseudoVal LDpred1.Inf 0.091 0.136 -0.045 1.23e-38 0.077 0.111 -0.034 7.15e-07
RheuArth SBayesR.PseudoVal LDpred1.Inf 0.124 0.136 -0.012 5.16e-03 0.119 0.111 0.008 3.59e-01
RheuArth LDpred2.MultiPRS LDpred1.Inf 0.151 0.136 0.014 3.74e-02 0.127 0.111 0.016 3.76e-02
RheuArth PRScs.PseudoVal LDpred1.Inf 0.162 0.136 0.026 1.28e-14 0.129 0.111 0.018 8.33e-03
RheuArth LDpred1.Inf LDpred1.Inf 0.136 0.136 0.000 1.00e+00 0.111 0.111 0.000 1.00e+00
RheuArth pT+clump.10FCVal LDpred1.Inf 0.111 0.136 -0.025 1.17e-05 0.103 0.111 -0.008 5.06e-01
RheuArth PRScs.MultiPRS LDpred1.Inf 0.166 0.136 0.029 2.41e-05 0.133 0.111 0.022 1.22e-04
RheuArth lassosum.PseudoVal LDpred1.Inf 0.114 0.136 -0.022 2.15e-08 0.089 0.111 -0.022 5.69e-03
RheuArth pT+clump.MultiPRS LDpred1.Inf 0.131 0.136 -0.005 4.56e-01 0.124 0.111 0.013 1.63e-01
RheuArth LDpred1.MultiPRS LDpred1.Inf 0.145 0.136 0.009 1.93e-01 0.119 0.111 0.008 1.11e-02
RheuArth PRScs.10FCVal LDpred1.Inf 0.161 0.136 0.025 1.17e-12 0.128 0.111 0.017 1.74e-02
RheuArth LDpred2.Inf LDpred1.Inf 0.085 0.136 -0.051 6.20e-46 0.072 0.111 -0.039 6.42e-08
RheuArth SBLUP.Inf LDpred1.Inf 0.112 0.136 -0.024 9.79e-20 0.097 0.111 -0.014 6.78e-03
RheuArth DBSLMM.PseudoVal LDpred1.Inf 0.142 0.136 0.006 1.56e-01 0.111 0.111 0.000 9.75e-01
RheuArth lassosum.MultiPRS LDpred1.Inf 0.183 0.136 0.046 3.03e-11 0.150 0.111 0.039 9.27e-09
RheuArth LDpred1.10FCVal LDpred1.Inf 0.136 0.136 0.000 9.77e-01 0.112 0.111 0.001 7.53e-01
RheuArth lassosum.10FCVal LDpred1.Inf 0.162 0.136 0.025 1.26e-12 0.130 0.111 0.019 9.06e-03
RheuArth LDpred2.10FCVal LDpred1.Inf 0.151 0.136 0.015 2.94e-04 0.128 0.111 0.017 3.88e-02
RheuArth LDpred1.Inf LDpred1.10FCVal 0.136 0.136 0.000 9.77e-01 0.111 0.112 -0.001 7.53e-01
RheuArth PRScs.MultiPRS LDpred1.10FCVal 0.166 0.136 0.029 2.37e-05 0.133 0.112 0.022 2.28e-04
RheuArth LDpred1.10FCVal LDpred1.10FCVal 0.136 0.136 0.000 1.00e+00 0.112 0.112 0.000 1.00e+00
RheuArth All.MultiPRS LDpred1.10FCVal 0.185 0.136 0.048 2.27e-12 0.161 0.112 0.050 1.88e-13
RheuArth SBayesR.PseudoVal LDpred1.10FCVal 0.124 0.136 -0.012 5.12e-03 0.119 0.112 0.007 3.91e-01
RheuArth DBSLMM.PseudoVal LDpred1.10FCVal 0.142 0.136 0.006 1.60e-01 0.111 0.112 -0.001 9.21e-01
RheuArth pT+clump.MultiPRS LDpred1.10FCVal 0.131 0.136 -0.005 4.58e-01 0.124 0.112 0.012 1.81e-01
RheuArth lassosum.MultiPRS LDpred1.10FCVal 0.183 0.136 0.046 2.97e-11 0.150 0.112 0.039 1.72e-08
RheuArth PRScs.10FCVal LDpred1.10FCVal 0.161 0.136 0.025 2.93e-12 0.128 0.112 0.016 2.36e-02
RheuArth lassosum.10FCVal LDpred1.10FCVal 0.162 0.136 0.025 3.16e-12 0.130 0.112 0.018 1.29e-02
RheuArth SBLUP.Inf LDpred1.10FCVal 0.112 0.136 -0.024 6.80e-20 0.097 0.112 -0.015 4.75e-03
RheuArth LDpred2.PseudoVal LDpred1.10FCVal 0.091 0.136 -0.045 2.89e-39 0.077 0.112 -0.035 4.04e-07
RheuArth pT+clump.10FCVal LDpred1.10FCVal 0.111 0.136 -0.025 1.25e-05 0.103 0.112 -0.008 4.74e-01
RheuArth LDpred2.MultiPRS LDpred1.10FCVal 0.151 0.136 0.014 3.71e-02 0.127 0.112 0.016 4.62e-02
RheuArth PRScs.PseudoVal LDpred1.10FCVal 0.162 0.136 0.026 4.09e-14 0.129 0.112 0.017 1.20e-02
RheuArth LDpred2.10FCVal LDpred1.10FCVal 0.151 0.136 0.015 3.09e-04 0.128 0.112 0.017 4.70e-02
RheuArth LDpred1.MultiPRS LDpred1.10FCVal 0.145 0.136 0.009 1.92e-01 0.119 0.112 0.007 1.54e-02
RheuArth LDpred2.Inf LDpred1.10FCVal 0.085 0.136 -0.051 1.35e-46 0.072 0.112 -0.040 3.55e-08
RheuArth lassosum.PseudoVal LDpred1.10FCVal 0.114 0.136 -0.022 1.67e-08 0.089 0.112 -0.022 4.24e-03
RheuArth LDpred1.Inf LDpred2.MultiPRS 0.136 0.151 -0.014 3.74e-02 0.111 0.127 -0.016 3.76e-02
RheuArth DBSLMM.PseudoVal LDpred2.MultiPRS 0.142 0.151 -0.009 2.16e-01 0.111 0.127 -0.017 3.37e-02
RheuArth SBLUP.Inf LDpred2.MultiPRS 0.112 0.151 -0.039 2.51e-08 0.097 0.127 -0.031 3.36e-04
RheuArth LDpred2.Inf LDpred2.MultiPRS 0.085 0.151 -0.066 4.35e-21 0.072 0.127 -0.055 8.96e-10
RheuArth pT+clump.10FCVal LDpred2.MultiPRS 0.111 0.151 -0.040 1.42e-08 0.103 0.127 -0.024 4.90e-02
RheuArth LDpred2.10FCVal LDpred2.MultiPRS 0.151 0.151 0.000 9.59e-01 0.128 0.127 0.001 5.19e-01
RheuArth PRScs.PseudoVal LDpred2.MultiPRS 0.162 0.151 0.012 9.50e-02 0.129 0.127 0.002 8.07e-01
RheuArth LDpred1.10FCVal LDpred2.MultiPRS 0.136 0.151 -0.014 3.71e-02 0.112 0.127 -0.016 4.62e-02
RheuArth All.MultiPRS LDpred2.MultiPRS 0.185 0.151 0.034 1.71e-32 0.161 0.127 0.034 3.84e-09
RheuArth SBayesR.PseudoVal LDpred2.MultiPRS 0.124 0.151 -0.027 1.31e-04 0.119 0.127 -0.008 4.55e-01
RheuArth lassosum.10FCVal LDpred2.MultiPRS 0.162 0.151 0.011 1.20e-01 0.130 0.127 0.002 7.25e-01
RheuArth pT+clump.MultiPRS LDpred2.MultiPRS 0.131 0.151 -0.020 4.78e-03 0.124 0.127 -0.003 7.59e-01
RheuArth lassosum.MultiPRS LDpred2.MultiPRS 0.183 0.151 0.032 4.42e-06 0.150 0.127 0.023 1.09e-03
RheuArth PRScs.10FCVal LDpred2.MultiPRS 0.161 0.151 0.010 1.36e-01 0.128 0.127 0.000 9.45e-01
RheuArth PRScs.MultiPRS LDpred2.MultiPRS 0.166 0.151 0.015 2.59e-06 0.133 0.127 0.006 3.67e-01
RheuArth lassosum.PseudoVal LDpred2.MultiPRS 0.114 0.151 -0.036 1.66e-07 0.089 0.127 -0.038 7.30e-05
RheuArth LDpred2.PseudoVal LDpred2.MultiPRS 0.091 0.151 -0.060 1.11e-17 0.077 0.127 -0.051 3.13e-09
RheuArth LDpred1.MultiPRS LDpred2.MultiPRS 0.145 0.151 -0.005 1.40e-01 0.119 0.127 -0.008 2.68e-01
RheuArth LDpred2.MultiPRS LDpred2.MultiPRS 0.151 0.151 0.000 1.00e+00 0.127 0.127 0.000 1.00e+00
RheuArth LDpred1.Inf LDpred2.10FCVal 0.136 0.151 -0.015 2.94e-04 0.111 0.128 -0.017 3.88e-02
RheuArth PRScs.MultiPRS LDpred2.10FCVal 0.166 0.151 0.014 3.70e-02 0.133 0.128 0.005 4.62e-01
RheuArth LDpred2.MultiPRS LDpred2.10FCVal 0.151 0.151 0.000 9.59e-01 0.127 0.128 -0.001 5.19e-01
RheuArth PRScs.PseudoVal LDpred2.10FCVal 0.162 0.151 0.011 5.79e-04 0.129 0.128 0.001 9.20e-01
RheuArth LDpred2.10FCVal LDpred2.10FCVal 0.151 0.151 0.000 1.00e+00 0.128 0.128 0.000 1.00e+00
RheuArth lassosum.MultiPRS LDpred2.10FCVal 0.183 0.151 0.031 5.78e-06 0.150 0.128 0.022 2.24e-03
RheuArth LDpred1.10FCVal LDpred2.10FCVal 0.136 0.151 -0.015 3.09e-04 0.112 0.128 -0.017 4.70e-02
RheuArth All.MultiPRS LDpred2.10FCVal 0.185 0.151 0.034 1.08e-06 0.161 0.128 0.033 4.06e-08
RheuArth SBayesR.PseudoVal LDpred2.10FCVal 0.124 0.151 -0.027 2.27e-06 0.119 0.128 -0.009 4.23e-01
RheuArth DBSLMM.PseudoVal LDpred2.10FCVal 0.142 0.151 -0.009 1.78e-02 0.111 0.128 -0.018 2.01e-02
RheuArth pT+clump.MultiPRS LDpred2.10FCVal 0.131 0.151 -0.020 4.19e-03 0.124 0.128 -0.004 6.98e-01
RheuArth lassosum.PseudoVal LDpred2.10FCVal 0.114 0.151 -0.037 8.81e-14 0.089 0.128 -0.039 9.95e-05
RheuArth PRScs.10FCVal LDpred2.10FCVal 0.161 0.151 0.010 2.16e-03 0.128 0.128 -0.001 9.37e-01
RheuArth lassosum.10FCVal LDpred2.10FCVal 0.162 0.151 0.010 2.81e-03 0.130 0.128 0.002 8.33e-01
RheuArth SBLUP.Inf LDpred2.10FCVal 0.112 0.151 -0.039 3.17e-17 0.097 0.128 -0.032 7.23e-04
RheuArth LDpred2.PseudoVal LDpred2.10FCVal 0.091 0.151 -0.060 6.14e-38 0.077 0.128 -0.052 4.18e-08
RheuArth pT+clump.10FCVal LDpred2.10FCVal 0.111 0.151 -0.040 3.66e-11 0.103 0.128 -0.025 4.03e-02
RheuArth LDpred2.Inf LDpred2.10FCVal 0.085 0.151 -0.066 6.68e-42 0.072 0.128 -0.056 1.22e-08
RheuArth LDpred1.MultiPRS LDpred2.10FCVal 0.145 0.151 -0.006 4.04e-01 0.119 0.128 -0.009 2.39e-01
RheuArth lassosum.10FCVal LDpred2.PseudoVal 0.162 0.091 0.070 9.12e-41 0.130 0.077 0.053 5.63e-07
RheuArth SBLUP.Inf LDpred2.PseudoVal 0.112 0.091 0.021 1.47e-46 0.097 0.077 0.020 5.03e-12
RheuArth SBayesR.PseudoVal LDpred2.PseudoVal 0.124 0.091 0.033 2.30e-14 0.119 0.077 0.042 1.03e-06
RheuArth All.MultiPRS LDpred2.PseudoVal 0.185 0.091 0.094 1.39e-41 0.161 0.077 0.085 3.01e-19
RheuArth PRScs.PseudoVal LDpred2.PseudoVal 0.162 0.091 0.071 1.45e-41 0.129 0.077 0.052 7.39e-07
RheuArth lassosum.MultiPRS LDpred2.PseudoVal 0.183 0.091 0.091 2.73e-39 0.150 0.077 0.074 3.15e-14
RheuArth PRScs.MultiPRS LDpred2.PseudoVal 0.166 0.091 0.074 7.81e-27 0.133 0.077 0.057 1.96e-09
RheuArth LDpred2.MultiPRS LDpred2.PseudoVal 0.151 0.091 0.060 1.11e-17 0.127 0.077 0.051 3.13e-09
RheuArth PRScs.10FCVal LDpred2.PseudoVal 0.161 0.091 0.070 2.78e-39 0.128 0.077 0.051 1.81e-06
RheuArth LDpred2.PseudoVal LDpred2.PseudoVal 0.091 0.091 0.000 1.00e+00 0.077 0.077 0.000 1.00e+00
RheuArth pT+clump.MultiPRS LDpred2.PseudoVal 0.131 0.091 0.040 1.21e-08 0.124 0.077 0.047 6.01e-06
RheuArth pT+clump.10FCVal LDpred2.PseudoVal 0.111 0.091 0.020 2.26e-03 0.103 0.077 0.027 4.23e-02
RheuArth lassosum.PseudoVal LDpred2.PseudoVal 0.114 0.091 0.023 3.18e-08 0.089 0.077 0.013 1.32e-01
RheuArth LDpred1.Inf LDpred2.PseudoVal 0.136 0.091 0.045 1.23e-38 0.111 0.077 0.034 7.15e-07
RheuArth LDpred1.MultiPRS LDpred2.PseudoVal 0.145 0.091 0.054 5.95e-15 0.119 0.077 0.042 7.86e-08
RheuArth LDpred1.10FCVal LDpred2.PseudoVal 0.136 0.091 0.045 2.89e-39 0.112 0.077 0.035 4.04e-07
RheuArth LDpred2.Inf LDpred2.PseudoVal 0.085 0.091 -0.006 4.76e-70 0.072 0.077 -0.004 1.35e-10
RheuArth LDpred2.10FCVal LDpred2.PseudoVal 0.151 0.091 0.060 6.14e-38 0.128 0.077 0.052 4.18e-08
RheuArth DBSLMM.PseudoVal LDpred2.PseudoVal 0.142 0.091 0.051 5.15e-19 0.111 0.077 0.034 2.97e-03
RheuArth pT+clump.MultiPRS LDpred2.Inf 0.131 0.085 0.046 5.56e-11 0.124 0.072 0.052 9.22e-07
RheuArth lassosum.MultiPRS LDpred2.Inf 0.183 0.085 0.098 2.27e-44 0.150 0.072 0.078 4.72e-15
RheuArth SBayesR.PseudoVal LDpred2.Inf 0.124 0.085 0.039 1.46e-19 0.119 0.072 0.047 5.94e-08
RheuArth All.MultiPRS LDpred2.Inf 0.185 0.085 0.100 7.60e-47 0.161 0.072 0.089 7.28e-20
RheuArth SBLUP.Inf LDpred2.Inf 0.112 0.085 0.027 1.54e-68 0.097 0.072 0.024 1.44e-15
RheuArth LDpred2.PseudoVal LDpred2.Inf 0.091 0.085 0.006 4.76e-70 0.077 0.072 0.004 1.35e-10
RheuArth PRScs.MultiPRS LDpred2.Inf 0.166 0.085 0.080 4.66e-31 0.133 0.072 0.061 4.06e-10
RheuArth LDpred2.MultiPRS LDpred2.Inf 0.151 0.085 0.066 4.35e-21 0.127 0.072 0.055 8.96e-10
RheuArth PRScs.10FCVal LDpred2.Inf 0.161 0.085 0.076 1.05e-43 0.128 0.072 0.056 4.44e-07
RheuArth LDpred1.Inf LDpred2.Inf 0.136 0.085 0.051 6.20e-46 0.111 0.072 0.039 6.42e-08
RheuArth LDpred1.MultiPRS LDpred2.Inf 0.145 0.085 0.060 4.34e-18 0.119 0.072 0.047 9.38e-09
RheuArth pT+clump.10FCVal LDpred2.Inf 0.111 0.085 0.026 7.88e-05 0.103 0.072 0.031 1.83e-02
RheuArth lassosum.PseudoVal LDpred2.Inf 0.114 0.085 0.029 1.23e-11 0.089 0.072 0.017 4.76e-02
RheuArth PRScs.PseudoVal LDpred2.Inf 0.162 0.085 0.077 4.19e-46 0.129 0.072 0.057 1.74e-07
RheuArth DBSLMM.PseudoVal LDpred2.Inf 0.142 0.085 0.057 2.08e-22 0.111 0.072 0.039 1.03e-03
RheuArth LDpred1.10FCVal LDpred2.Inf 0.136 0.085 0.051 1.35e-46 0.112 0.072 0.040 3.55e-08
RheuArth LDpred2.Inf LDpred2.Inf 0.085 0.085 0.000 1.00e+00 0.072 0.072 0.000 1.00e+00
RheuArth lassosum.10FCVal LDpred2.Inf 0.162 0.085 0.076 2.73e-45 0.130 0.072 0.058 1.31e-07
RheuArth LDpred2.10FCVal LDpred2.Inf 0.151 0.085 0.066 6.68e-42 0.128 0.072 0.056 1.22e-08
RheuArth PRScs.10FCVal PRScs.MultiPRS 0.161 0.166 -0.004 5.20e-01 0.128 0.133 -0.005 2.00e-02
RheuArth LDpred1.10FCVal PRScs.MultiPRS 0.136 0.166 -0.029 2.37e-05 0.112 0.133 -0.022 2.28e-04
RheuArth lassosum.MultiPRS PRScs.MultiPRS 0.183 0.166 0.017 1.37e-02 0.150 0.133 0.017 1.07e-05
RheuArth LDpred2.MultiPRS PRScs.MultiPRS 0.151 0.166 -0.015 2.59e-06 0.127 0.133 -0.006 3.67e-01
RheuArth All.MultiPRS PRScs.MultiPRS 0.185 0.166 0.019 1.02e-21 0.161 0.133 0.028 7.09e-12
RheuArth PRScs.PseudoVal PRScs.MultiPRS 0.162 0.166 -0.003 6.41e-01 0.129 0.133 -0.004 4.66e-02
RheuArth LDpred1.MultiPRS PRScs.MultiPRS 0.145 0.166 -0.020 4.04e-15 0.119 0.133 -0.014 6.35e-03
RheuArth pT+clump.MultiPRS PRScs.MultiPRS 0.131 0.166 -0.034 7.69e-07 0.124 0.133 -0.009 3.36e-01
RheuArth lassosum.PseudoVal PRScs.MultiPRS 0.114 0.166 -0.051 1.80e-13 0.089 0.133 -0.044 3.08e-08
RheuArth SBayesR.PseudoVal PRScs.MultiPRS 0.124 0.166 -0.041 2.42e-09 0.119 0.133 -0.014 1.57e-01
RheuArth DBSLMM.PseudoVal PRScs.MultiPRS 0.142 0.166 -0.023 7.53e-04 0.111 0.133 -0.022 6.67e-06
RheuArth SBLUP.Inf PRScs.MultiPRS 0.112 0.166 -0.054 1.12e-14 0.097 0.133 -0.037 6.73e-06
RheuArth LDpred2.Inf PRScs.MultiPRS 0.085 0.166 -0.080 4.66e-31 0.072 0.133 -0.061 4.06e-10
RheuArth pT+clump.10FCVal PRScs.MultiPRS 0.111 0.166 -0.054 6.47e-15 0.103 0.133 -0.030 6.80e-03
RheuArth LDpred2.10FCVal PRScs.MultiPRS 0.151 0.166 -0.014 3.70e-02 0.128 0.133 -0.005 4.62e-01
RheuArth lassosum.10FCVal PRScs.MultiPRS 0.162 0.166 -0.004 5.61e-01 0.130 0.133 -0.003 3.74e-01
RheuArth LDpred2.PseudoVal PRScs.MultiPRS 0.091 0.166 -0.074 7.81e-27 0.077 0.133 -0.057 1.96e-09
RheuArth LDpred1.Inf PRScs.MultiPRS 0.136 0.166 -0.029 2.41e-05 0.111 0.133 -0.022 1.22e-04
RheuArth PRScs.MultiPRS PRScs.MultiPRS 0.166 0.166 0.000 1.00e+00 0.133 0.133 0.000 1.00e+00
RheuArth LDpred2.PseudoVal PRScs.10FCVal 0.091 0.161 -0.070 2.78e-39 0.077 0.128 -0.051 1.81e-06
RheuArth PRScs.10FCVal PRScs.10FCVal 0.161 0.161 0.000 1.00e+00 0.128 0.128 0.000 1.00e+00
RheuArth LDpred2.MultiPRS PRScs.10FCVal 0.151 0.161 -0.010 1.36e-01 0.127 0.128 0.000 9.45e-01
RheuArth pT+clump.MultiPRS PRScs.10FCVal 0.131 0.161 -0.030 1.69e-05 0.124 0.128 -0.004 7.08e-01
RheuArth LDpred1.Inf PRScs.10FCVal 0.136 0.161 -0.025 1.17e-12 0.111 0.128 -0.017 1.74e-02
RheuArth LDpred1.MultiPRS PRScs.10FCVal 0.145 0.161 -0.016 2.30e-02 0.119 0.128 -0.009 1.62e-01
RheuArth pT+clump.10FCVal PRScs.10FCVal 0.111 0.161 -0.050 1.59e-20 0.103 0.128 -0.024 2.54e-02
RheuArth lassosum.PseudoVal PRScs.10FCVal 0.114 0.161 -0.047 2.29e-23 0.089 0.128 -0.038 4.46e-05
RheuArth PRScs.PseudoVal PRScs.10FCVal 0.162 0.161 0.001 9.33e-02 0.129 0.128 0.001 4.34e-01
RheuArth DBSLMM.PseudoVal PRScs.10FCVal 0.142 0.161 -0.019 6.05e-19 0.111 0.128 -0.017 8.66e-05
RheuArth SBLUP.Inf PRScs.10FCVal 0.112 0.161 -0.049 7.77e-25 0.097 0.128 -0.031 1.14e-03
RheuArth LDpred2.Inf PRScs.10FCVal 0.085 0.161 -0.076 1.05e-43 0.072 0.128 -0.056 4.44e-07
RheuArth lassosum.10FCVal PRScs.10FCVal 0.162 0.161 0.000 8.14e-01 0.130 0.128 0.002 5.84e-01
RheuArth LDpred2.10FCVal PRScs.10FCVal 0.151 0.161 -0.010 2.16e-03 0.128 0.128 0.001 9.37e-01
RheuArth lassosum.MultiPRS PRScs.10FCVal 0.183 0.161 0.022 1.94e-03 0.150 0.128 0.022 4.05e-07
RheuArth LDpred1.10FCVal PRScs.10FCVal 0.136 0.161 -0.025 2.93e-12 0.112 0.128 -0.016 2.36e-02
RheuArth All.MultiPRS PRScs.10FCVal 0.185 0.161 0.024 6.00e-04 0.161 0.128 0.034 9.61e-13
RheuArth SBayesR.PseudoVal PRScs.10FCVal 0.124 0.161 -0.037 2.74e-12 0.119 0.128 -0.009 4.16e-01
RheuArth PRScs.MultiPRS PRScs.10FCVal 0.166 0.161 0.004 5.20e-01 0.133 0.128 0.005 2.00e-02
RheuArth All.MultiPRS PRScs.PseudoVal 0.185 0.162 0.022 1.13e-03 0.161 0.129 0.032 1.52e-12
RheuArth pT+clump.MultiPRS PRScs.PseudoVal 0.131 0.162 -0.031 7.57e-06 0.124 0.129 -0.005 6.19e-01
RheuArth LDpred2.PseudoVal PRScs.PseudoVal 0.091 0.162 -0.071 1.45e-41 0.077 0.129 -0.052 7.39e-07
RheuArth SBayesR.PseudoVal PRScs.PseudoVal 0.124 0.162 -0.038 3.26e-13 0.119 0.129 -0.010 3.50e-01
RheuArth LDpred2.MultiPRS PRScs.PseudoVal 0.151 0.162 -0.012 9.50e-02 0.127 0.129 -0.002 8.07e-01
RheuArth SBLUP.Inf PRScs.PseudoVal 0.112 0.162 -0.050 9.11e-27 0.097 0.129 -0.032 5.86e-04
RheuArth LDpred1.Inf PRScs.PseudoVal 0.136 0.162 -0.026 1.28e-14 0.111 0.129 -0.018 8.33e-03
RheuArth PRScs.10FCVal PRScs.PseudoVal 0.161 0.162 -0.001 9.33e-02 0.128 0.129 -0.001 4.34e-01
RheuArth LDpred2.Inf PRScs.PseudoVal 0.085 0.162 -0.077 4.19e-46 0.072 0.129 -0.057 1.74e-07
RheuArth PRScs.PseudoVal PRScs.PseudoVal 0.162 0.162 0.000 1.00e+00 0.129 0.129 0.000 1.00e+00
RheuArth LDpred2.10FCVal PRScs.PseudoVal 0.151 0.162 -0.011 5.79e-04 0.128 0.129 -0.001 9.20e-01
RheuArth pT+clump.10FCVal PRScs.PseudoVal 0.111 0.162 -0.051 1.73e-21 0.103 0.129 -0.026 1.89e-02
RheuArth PRScs.MultiPRS PRScs.PseudoVal 0.166 0.162 0.003 6.41e-01 0.133 0.129 0.004 4.66e-02
RheuArth lassosum.PseudoVal PRScs.PseudoVal 0.114 0.162 -0.048 4.55e-25 0.089 0.129 -0.040 1.94e-05
RheuArth lassosum.10FCVal PRScs.PseudoVal 0.162 0.162 -0.001 6.61e-01 0.130 0.129 0.001 8.17e-01
RheuArth LDpred1.MultiPRS PRScs.PseudoVal 0.145 0.162 -0.017 1.43e-02 0.119 0.129 -0.010 9.98e-02
RheuArth lassosum.MultiPRS PRScs.PseudoVal 0.183 0.162 0.020 3.47e-03 0.150 0.129 0.021 7.80e-07
RheuArth LDpred1.10FCVal PRScs.PseudoVal 0.136 0.162 -0.026 4.09e-14 0.112 0.129 -0.017 1.20e-02
RheuArth DBSLMM.PseudoVal PRScs.PseudoVal 0.142 0.162 -0.020 2.04e-21 0.111 0.129 -0.018 2.45e-05
RheuArth All.MultiPRS pT+clump.MultiPRS 0.185 0.131 0.054 1.01e-14 0.161 0.124 0.037 2.25e-07
RheuArth SBayesR.PseudoVal pT+clump.MultiPRS 0.124 0.131 -0.007 3.21e-01 0.119 0.124 -0.005 4.74e-01
RheuArth LDpred1.MultiPRS pT+clump.MultiPRS 0.145 0.131 0.014 4.16e-02 0.119 0.124 -0.005 5.93e-01
RheuArth pT+clump.MultiPRS pT+clump.MultiPRS 0.131 0.131 0.000 1.00e+00 0.124 0.124 0.000 1.00e+00
RheuArth lassosum.PseudoVal pT+clump.MultiPRS 0.114 0.131 -0.017 1.61e-02 0.089 0.124 -0.035 4.18e-04
RheuArth PRScs.10FCVal pT+clump.MultiPRS 0.161 0.131 0.030 1.69e-05 0.128 0.124 0.004 7.08e-01
RheuArth DBSLMM.PseudoVal pT+clump.MultiPRS 0.142 0.131 0.011 1.13e-01 0.111 0.124 -0.013 2.00e-01
RheuArth SBLUP.Inf pT+clump.MultiPRS 0.112 0.131 -0.019 6.28e-03 0.097 0.124 -0.027 3.57e-03
RheuArth LDpred2.Inf pT+clump.MultiPRS 0.085 0.131 -0.046 5.56e-11 0.072 0.124 -0.052 9.22e-07
RheuArth pT+clump.10FCVal pT+clump.MultiPRS 0.111 0.131 -0.020 4.36e-03 0.103 0.124 -0.021 2.56e-04
RheuArth LDpred2.10FCVal pT+clump.MultiPRS 0.151 0.131 0.020 4.19e-03 0.128 0.124 0.004 6.98e-01
RheuArth PRScs.PseudoVal pT+clump.MultiPRS 0.162 0.131 0.031 7.57e-06 0.129 0.124 0.005 6.19e-01
RheuArth LDpred1.10FCVal pT+clump.MultiPRS 0.136 0.131 0.005 4.58e-01 0.112 0.124 -0.012 1.81e-01
RheuArth LDpred1.Inf pT+clump.MultiPRS 0.136 0.131 0.005 4.56e-01 0.111 0.124 -0.013 1.63e-01
RheuArth PRScs.MultiPRS pT+clump.MultiPRS 0.166 0.131 0.034 7.69e-07 0.133 0.124 0.009 3.36e-01
RheuArth lassosum.10FCVal pT+clump.MultiPRS 0.162 0.131 0.030 1.25e-05 0.130 0.124 0.006 5.22e-01
RheuArth LDpred2.PseudoVal pT+clump.MultiPRS 0.091 0.131 -0.040 1.21e-08 0.077 0.124 -0.047 6.01e-06
RheuArth lassosum.MultiPRS pT+clump.MultiPRS 0.183 0.131 0.051 1.21e-13 0.150 0.124 0.026 1.26e-03
RheuArth LDpred2.MultiPRS pT+clump.MultiPRS 0.151 0.131 0.020 4.78e-03 0.127 0.124 0.003 7.59e-01
RheuArth LDpred2.10FCVal pT+clump.10FCVal 0.151 0.111 0.040 3.66e-11 0.128 0.103 0.025 4.03e-02
RheuArth pT+clump.MultiPRS pT+clump.10FCVal 0.131 0.111 0.020 4.36e-03 0.124 0.103 0.021 2.56e-04
RheuArth LDpred2.Inf pT+clump.10FCVal 0.085 0.111 -0.026 7.88e-05 0.072 0.103 -0.031 1.83e-02
RheuArth SBayesR.PseudoVal pT+clump.10FCVal 0.124 0.111 0.013 4.47e-03 0.119 0.103 0.016 8.06e-02
RheuArth PRScs.MultiPRS pT+clump.10FCVal 0.166 0.111 0.054 6.47e-15 0.133 0.103 0.030 6.80e-03
RheuArth SBLUP.Inf pT+clump.10FCVal 0.112 0.111 0.001 8.97e-01 0.097 0.103 -0.007 5.84e-01
RheuArth lassosum.MultiPRS pT+clump.10FCVal 0.183 0.111 0.071 7.40e-25 0.150 0.103 0.047 1.39e-06
RheuArth PRScs.10FCVal pT+clump.10FCVal 0.161 0.111 0.050 1.59e-20 0.128 0.103 0.024 2.54e-02
RheuArth LDpred2.MultiPRS pT+clump.10FCVal 0.151 0.111 0.040 1.42e-08 0.127 0.103 0.024 4.90e-02
RheuArth lassosum.10FCVal pT+clump.10FCVal 0.162 0.111 0.050 3.22e-22 0.130 0.103 0.027 1.18e-02
RheuArth LDpred2.PseudoVal pT+clump.10FCVal 0.091 0.111 -0.020 2.26e-03 0.077 0.103 -0.027 4.23e-02
RheuArth LDpred1.MultiPRS pT+clump.10FCVal 0.145 0.111 0.034 1.01e-06 0.119 0.103 0.016 1.69e-01
RheuArth pT+clump.10FCVal pT+clump.10FCVal 0.111 0.111 0.000 1.00e+00 0.103 0.103 0.000 1.00e+00
RheuArth All.MultiPRS pT+clump.10FCVal 0.185 0.111 0.074 4.10e-26 0.161 0.103 0.058 4.53e-11
RheuArth LDpred1.Inf pT+clump.10FCVal 0.136 0.111 0.025 1.17e-05 0.111 0.103 0.008 5.06e-01
RheuArth DBSLMM.PseudoVal pT+clump.10FCVal 0.142 0.111 0.031 6.56e-09 0.111 0.103 0.007 4.95e-01
RheuArth LDpred1.10FCVal pT+clump.10FCVal 0.136 0.111 0.025 1.25e-05 0.112 0.103 0.008 4.74e-01
RheuArth lassosum.PseudoVal pT+clump.10FCVal 0.114 0.111 0.003 6.14e-01 0.089 0.103 -0.014 2.56e-01
RheuArth PRScs.PseudoVal pT+clump.10FCVal 0.162 0.111 0.051 1.73e-21 0.129 0.103 0.026 1.89e-02
RheuArth pT+clump.MultiPRS SBayesR.PseudoVal 0.131 0.124 0.007 3.21e-01 0.124 0.119 0.005 4.74e-01
RheuArth LDpred1.10FCVal SBayesR.PseudoVal 0.136 0.124 0.012 5.12e-03 0.112 0.119 -0.007 3.91e-01
RheuArth PRScs.10FCVal SBayesR.PseudoVal 0.161 0.124 0.037 2.74e-12 0.128 0.119 0.009 4.16e-01
RheuArth LDpred2.10FCVal SBayesR.PseudoVal 0.151 0.124 0.027 2.27e-06 0.128 0.119 0.009 4.23e-01
RheuArth lassosum.10FCVal SBayesR.PseudoVal 0.162 0.124 0.037 1.17e-13 0.130 0.119 0.011 2.92e-01
RheuArth LDpred2.PseudoVal SBayesR.PseudoVal 0.091 0.124 -0.033 2.30e-14 0.077 0.119 -0.042 1.03e-06
RheuArth lassosum.MultiPRS SBayesR.PseudoVal 0.183 0.124 0.058 4.17e-17 0.150 0.119 0.031 4.64e-04
RheuArth LDpred2.MultiPRS SBayesR.PseudoVal 0.151 0.124 0.027 1.31e-04 0.127 0.119 0.008 4.55e-01
RheuArth All.MultiPRS SBayesR.PseudoVal 0.185 0.124 0.061 2.02e-18 0.161 0.119 0.042 2.05e-07
RheuArth PRScs.PseudoVal SBayesR.PseudoVal 0.162 0.124 0.038 3.26e-13 0.129 0.119 0.010 3.50e-01
RheuArth LDpred1.MultiPRS SBayesR.PseudoVal 0.145 0.124 0.021 2.31e-03 0.119 0.119 0.000 9.95e-01
RheuArth pT+clump.10FCVal SBayesR.PseudoVal 0.111 0.124 -0.013 4.47e-03 0.103 0.119 -0.016 8.06e-02
RheuArth lassosum.PseudoVal SBayesR.PseudoVal 0.114 0.124 -0.010 4.28e-02 0.089 0.119 -0.030 2.34e-03
RheuArth SBayesR.PseudoVal SBayesR.PseudoVal 0.124 0.124 0.000 1.00e+00 0.119 0.119 0.000 1.00e+00
RheuArth DBSLMM.PseudoVal SBayesR.PseudoVal 0.142 0.124 0.018 7.22e-04 0.111 0.119 -0.008 4.44e-01
RheuArth SBLUP.Inf SBayesR.PseudoVal 0.112 0.124 -0.012 1.36e-03 0.097 0.119 -0.022 3.49e-03
RheuArth LDpred2.Inf SBayesR.PseudoVal 0.085 0.124 -0.039 1.46e-19 0.072 0.119 -0.047 5.94e-08
RheuArth LDpred1.Inf SBayesR.PseudoVal 0.136 0.124 0.012 5.16e-03 0.111 0.119 -0.008 3.59e-01
RheuArth PRScs.MultiPRS SBayesR.PseudoVal 0.166 0.124 0.041 2.42e-09 0.133 0.119 0.014 1.57e-01
RheuArth LDpred2.10FCVal SBLUP.Inf 0.151 0.112 0.039 3.17e-17 0.128 0.097 0.032 7.23e-04
RheuArth PRScs.PseudoVal SBLUP.Inf 0.162 0.112 0.050 9.11e-27 0.129 0.097 0.032 5.86e-04
RheuArth LDpred1.10FCVal SBLUP.Inf 0.136 0.112 0.024 6.80e-20 0.112 0.097 0.015 4.75e-03
RheuArth LDpred2.Inf SBLUP.Inf 0.085 0.112 -0.027 1.54e-68 0.072 0.097 -0.024 1.44e-15
RheuArth SBayesR.PseudoVal SBLUP.Inf 0.124 0.112 0.012 1.36e-03 0.119 0.097 0.022 3.49e-03
RheuArth lassosum.10FCVal SBLUP.Inf 0.162 0.112 0.050 2.47e-26 0.130 0.097 0.033 4.26e-04
RheuArth pT+clump.MultiPRS SBLUP.Inf 0.131 0.112 0.019 6.28e-03 0.124 0.097 0.027 3.57e-03
RheuArth lassosum.MultiPRS SBLUP.Inf 0.183 0.112 0.071 3.93e-24 0.150 0.097 0.054 2.26e-10
RheuArth PRScs.10FCVal SBLUP.Inf 0.161 0.112 0.049 7.77e-25 0.128 0.097 0.031 1.14e-03
RheuArth PRScs.MultiPRS SBLUP.Inf 0.166 0.112 0.054 1.12e-14 0.133 0.097 0.037 6.73e-06
RheuArth LDpred1.MultiPRS SBLUP.Inf 0.145 0.112 0.033 1.54e-06 0.119 0.097 0.022 5.58e-04
RheuArth LDpred2.PseudoVal SBLUP.Inf 0.091 0.112 -0.021 1.47e-46 0.077 0.097 -0.020 5.03e-12
RheuArth LDpred1.Inf SBLUP.Inf 0.136 0.112 0.024 9.79e-20 0.111 0.097 0.014 6.78e-03
RheuArth LDpred2.MultiPRS SBLUP.Inf 0.151 0.112 0.039 2.51e-08 0.127 0.097 0.031 3.36e-04
RheuArth All.MultiPRS SBLUP.Inf 0.185 0.112 0.073 7.80e-26 0.161 0.097 0.065 8.79e-15
RheuArth SBLUP.Inf SBLUP.Inf 0.112 0.112 0.000 1.00e+00 0.097 0.097 0.000 1.00e+00
RheuArth DBSLMM.PseudoVal SBLUP.Inf 0.142 0.112 0.030 8.95e-09 0.111 0.097 0.014 1.80e-01
RheuArth pT+clump.10FCVal SBLUP.Inf 0.111 0.112 -0.001 8.97e-01 0.103 0.097 0.007 5.84e-01
RheuArth lassosum.PseudoVal SBLUP.Inf 0.114 0.112 0.002 5.39e-01 0.089 0.097 -0.007 3.37e-01
Prostate_Cancer LDpred2.PseudoVal All.MultiPRS 0.139 0.186 -0.047 7.98e-12 0.133 0.181 -0.048 1.76e-10
Prostate_Cancer pT+clump.10FCVal All.MultiPRS 0.152 0.186 -0.034 8.40e-07 0.166 0.181 -0.015 2.88e-02
Prostate_Cancer LDpred2.MultiPRS All.MultiPRS 0.183 0.186 -0.003 6.19e-01 0.175 0.181 -0.006 9.08e-02
Prostate_Cancer PRScs.PseudoVal All.MultiPRS 0.183 0.186 -0.004 5.80e-01 0.172 0.181 -0.009 1.53e-02
Prostate_Cancer LDpred1.Inf All.MultiPRS 0.143 0.186 -0.043 3.80e-10 0.133 0.181 -0.048 5.21e-11
Prostate_Cancer PRScs.MultiPRS All.MultiPRS 0.184 0.186 -0.003 7.14e-01 0.173 0.181 -0.008 2.74e-02
Prostate_Cancer LDpred2.Inf All.MultiPRS 0.135 0.186 -0.051 1.64e-13 0.129 0.181 -0.052 2.66e-11
Prostate_Cancer lassosum.10FCVal All.MultiPRS 0.180 0.186 -0.006 3.57e-01 0.177 0.181 -0.004 3.70e-01
Prostate_Cancer LDpred2.10FCVal All.MultiPRS 0.183 0.186 -0.003 6.39e-01 0.173 0.181 -0.008 3.74e-02
Prostate_Cancer lassosum.MultiPRS All.MultiPRS 0.187 0.186 0.001 9.28e-01 0.181 0.181 0.000 9.65e-01
Prostate_Cancer LDpred1.10FCVal All.MultiPRS 0.165 0.186 -0.021 2.24e-03 0.152 0.181 -0.029 2.30e-07
Prostate_Cancer All.MultiPRS All.MultiPRS 0.186 0.186 0.000 1.00e+00 0.181 0.181 0.000 1.00e+00
Prostate_Cancer SBayesR.PseudoVal All.MultiPRS 0.176 0.186 -0.010 1.48e-01 0.171 0.181 -0.010 2.71e-02
Prostate_Cancer LDpred1.MultiPRS All.MultiPRS 0.164 0.186 -0.022 1.53e-03 0.149 0.181 -0.032 2.66e-08
Prostate_Cancer pT+clump.MultiPRS All.MultiPRS 0.168 0.186 -0.018 8.51e-03 0.175 0.181 -0.007 2.34e-01
Prostate_Cancer lassosum.PseudoVal All.MultiPRS 0.168 0.186 -0.018 8.99e-03 0.164 0.181 -0.017 1.72e-03
Prostate_Cancer PRScs.10FCVal All.MultiPRS 0.181 0.186 -0.006 4.20e-01 0.176 0.181 -0.005 2.50e-01
Prostate_Cancer DBSLMM.PseudoVal All.MultiPRS 0.176 0.186 -0.010 1.49e-01 0.166 0.181 -0.015 1.07e-03
Prostate_Cancer SBLUP.Inf All.MultiPRS 0.137 0.186 -0.050 8.19e-13 0.128 0.181 -0.053 1.01e-11
Prostate_Cancer SBayesR.PseudoVal DBSLMM.PseudoVal 0.176 0.176 0.000 9.91e-01 0.171 0.166 0.005 3.65e-01
Prostate_Cancer LDpred2.Inf DBSLMM.PseudoVal 0.135 0.176 -0.041 3.72e-34 0.129 0.166 -0.037 4.57e-08
Prostate_Cancer pT+clump.10FCVal DBSLMM.PseudoVal 0.152 0.176 -0.024 7.26e-11 0.166 0.166 0.001 9.45e-01
Prostate_Cancer PRScs.10FCVal DBSLMM.PseudoVal 0.181 0.176 0.004 1.62e-02 0.176 0.166 0.011 3.19e-03
Prostate_Cancer PRScs.PseudoVal DBSLMM.PseudoVal 0.183 0.176 0.006 5.43e-04 0.172 0.166 0.006 8.06e-02
Prostate_Cancer pT+clump.MultiPRS DBSLMM.PseudoVal 0.168 0.176 -0.008 2.33e-01 0.175 0.166 0.009 1.02e-01
Prostate_Cancer LDpred1.Inf DBSLMM.PseudoVal 0.143 0.176 -0.033 3.58e-26 0.133 0.166 -0.033 1.87e-07
Prostate_Cancer lassosum.MultiPRS DBSLMM.PseudoVal 0.187 0.176 0.011 1.26e-01 0.181 0.166 0.016 1.88e-04
Prostate_Cancer LDpred2.10FCVal DBSLMM.PseudoVal 0.183 0.176 0.007 1.39e-03 0.173 0.166 0.008 7.03e-02
Prostate_Cancer lassosum.10FCVal DBSLMM.PseudoVal 0.180 0.176 0.004 1.64e-01 0.177 0.166 0.012 2.45e-02
Prostate_Cancer LDpred1.10FCVal DBSLMM.PseudoVal 0.165 0.176 -0.011 7.93e-06 0.152 0.166 -0.014 4.95e-03
Prostate_Cancer LDpred1.MultiPRS DBSLMM.PseudoVal 0.164 0.176 -0.012 8.52e-02 0.149 0.166 -0.016 8.68e-04
Prostate_Cancer PRScs.MultiPRS DBSLMM.PseudoVal 0.184 0.176 0.007 2.84e-01 0.173 0.166 0.007 2.83e-02
Prostate_Cancer All.MultiPRS DBSLMM.PseudoVal 0.186 0.176 0.010 1.49e-01 0.181 0.166 0.015 1.07e-03
Prostate_Cancer LDpred2.PseudoVal DBSLMM.PseudoVal 0.139 0.176 -0.037 1.19e-30 0.133 0.166 -0.033 3.58e-07
Prostate_Cancer DBSLMM.PseudoVal DBSLMM.PseudoVal 0.176 0.176 0.000 1.00e+00 0.166 0.166 0.000 1.00e+00
Prostate_Cancer LDpred2.MultiPRS DBSLMM.PseudoVal 0.183 0.176 0.007 3.46e-01 0.175 0.166 0.009 2.19e-02
Prostate_Cancer lassosum.PseudoVal DBSLMM.PseudoVal 0.168 0.176 -0.008 1.21e-02 0.164 0.166 -0.002 7.63e-01
Prostate_Cancer SBLUP.Inf DBSLMM.PseudoVal 0.137 0.176 -0.040 6.96e-33 0.128 0.166 -0.038 1.26e-08
Prostate_Cancer SBayesR.PseudoVal lassosum.MultiPRS 0.176 0.187 -0.011 1.26e-01 0.171 0.181 -0.010 5.96e-02
Prostate_Cancer LDpred2.10FCVal lassosum.MultiPRS 0.183 0.187 -0.004 5.77e-01 0.173 0.181 -0.008 1.60e-02
Prostate_Cancer LDpred1.10FCVal lassosum.MultiPRS 0.165 0.187 -0.022 1.73e-03 0.152 0.181 -0.029 1.16e-08
Prostate_Cancer LDpred2.Inf lassosum.MultiPRS 0.135 0.187 -0.052 9.67e-14 0.129 0.181 -0.052 2.18e-12
Prostate_Cancer PRScs.10FCVal lassosum.MultiPRS 0.181 0.187 -0.006 3.72e-01 0.176 0.181 -0.005 1.58e-01
Prostate_Cancer PRScs.MultiPRS lassosum.MultiPRS 0.184 0.187 -0.003 4.26e-02 0.173 0.181 -0.008 6.54e-03
Prostate_Cancer pT+clump.MultiPRS lassosum.MultiPRS 0.168 0.187 -0.019 6.46e-03 0.175 0.181 -0.007 1.86e-01
Prostate_Cancer lassosum.MultiPRS lassosum.MultiPRS 0.187 0.187 0.000 1.00e+00 0.181 0.181 0.000 1.00e+00
Prostate_Cancer lassosum.PseudoVal lassosum.MultiPRS 0.168 0.187 -0.019 7.06e-03 0.164 0.181 -0.018 1.66e-04
Prostate_Cancer LDpred2.MultiPRS lassosum.MultiPRS 0.183 0.187 -0.004 5.56e-01 0.175 0.181 -0.007 4.75e-02
Prostate_Cancer LDpred1.MultiPRS lassosum.MultiPRS 0.164 0.187 -0.023 7.43e-18 0.149 0.181 -0.032 8.09e-10
Prostate_Cancer LDpred2.PseudoVal lassosum.MultiPRS 0.139 0.187 -0.048 4.82e-12 0.133 0.181 -0.048 1.32e-11
Prostate_Cancer LDpred1.Inf lassosum.MultiPRS 0.143 0.187 -0.044 2.42e-10 0.133 0.181 -0.048 2.52e-12
Prostate_Cancer pT+clump.10FCVal lassosum.MultiPRS 0.152 0.187 -0.035 5.96e-07 0.166 0.181 -0.015 2.26e-02
Prostate_Cancer lassosum.10FCVal lassosum.MultiPRS 0.180 0.187 -0.007 3.14e-01 0.177 0.181 -0.004 9.85e-02
Prostate_Cancer SBLUP.Inf lassosum.MultiPRS 0.137 0.187 -0.050 4.67e-13 0.128 0.181 -0.053 6.18e-13
Prostate_Cancer DBSLMM.PseudoVal lassosum.MultiPRS 0.176 0.187 -0.011 1.26e-01 0.166 0.181 -0.016 1.88e-04
Prostate_Cancer All.MultiPRS lassosum.MultiPRS 0.186 0.187 -0.001 9.28e-01 0.181 0.181 0.000 9.65e-01
Prostate_Cancer PRScs.PseudoVal lassosum.MultiPRS 0.183 0.187 -0.004 5.21e-01 0.172 0.181 -0.009 4.79e-03
Prostate_Cancer LDpred1.Inf lassosum.PseudoVal 0.143 0.168 -0.025 5.16e-07 0.133 0.164 -0.031 2.09e-03
Prostate_Cancer PRScs.10FCVal lassosum.PseudoVal 0.181 0.168 0.013 1.55e-06 0.176 0.164 0.013 1.27e-02
Prostate_Cancer LDpred2.MultiPRS lassosum.PseudoVal 0.183 0.168 0.015 3.46e-02 0.175 0.164 0.011 3.85e-02
Prostate_Cancer lassosum.PseudoVal lassosum.PseudoVal 0.168 0.168 0.000 1.00e+00 0.164 0.164 0.000 1.00e+00
Prostate_Cancer PRScs.PseudoVal lassosum.PseudoVal 0.183 0.168 0.014 1.14e-07 0.172 0.164 0.008 1.26e-01
Prostate_Cancer DBSLMM.PseudoVal lassosum.PseudoVal 0.176 0.168 0.008 1.21e-02 0.166 0.164 0.002 7.63e-01
Prostate_Cancer SBLUP.Inf lassosum.PseudoVal 0.137 0.168 -0.031 4.95e-09 0.128 0.164 -0.036 8.48e-04
Prostate_Cancer LDpred2.Inf lassosum.PseudoVal 0.135 0.168 -0.033 8.14e-10 0.129 0.164 -0.035 1.11e-03
Prostate_Cancer pT+clump.10FCVal lassosum.PseudoVal 0.152 0.168 -0.016 9.05e-08 0.166 0.164 0.002 6.78e-01
Prostate_Cancer LDpred2.10FCVal lassosum.PseudoVal 0.183 0.168 0.015 3.31e-09 0.173 0.164 0.010 5.28e-02
Prostate_Cancer lassosum.MultiPRS lassosum.PseudoVal 0.187 0.168 0.019 7.06e-03 0.181 0.164 0.018 1.66e-04
Prostate_Cancer LDpred1.10FCVal lassosum.PseudoVal 0.165 0.168 -0.003 4.37e-01 0.152 0.164 -0.012 1.26e-01
Prostate_Cancer All.MultiPRS lassosum.PseudoVal 0.186 0.168 0.018 8.99e-03 0.181 0.164 0.017 1.72e-03
Prostate_Cancer SBayesR.PseudoVal lassosum.PseudoVal 0.176 0.168 0.008 3.42e-04 0.171 0.164 0.007 9.86e-02
Prostate_Cancer lassosum.10FCVal lassosum.PseudoVal 0.180 0.168 0.012 3.97e-07 0.177 0.164 0.014 3.45e-03
Prostate_Cancer pT+clump.MultiPRS lassosum.PseudoVal 0.168 0.168 0.000 9.88e-01 0.175 0.164 0.011 9.03e-02
Prostate_Cancer LDpred2.PseudoVal lassosum.PseudoVal 0.139 0.168 -0.029 2.15e-08 0.133 0.164 -0.031 2.83e-03
Prostate_Cancer LDpred1.MultiPRS lassosum.PseudoVal 0.164 0.168 -0.004 5.82e-01 0.149 0.164 -0.014 6.69e-02
Prostate_Cancer PRScs.MultiPRS lassosum.PseudoVal 0.184 0.168 0.016 2.52e-02 0.173 0.164 0.009 7.34e-02
Prostate_Cancer lassosum.10FCVal lassosum.10FCVal 0.180 0.180 0.000 1.00e+00 0.177 0.177 0.000 1.00e+00
Prostate_Cancer pT+clump.MultiPRS lassosum.10FCVal 0.168 0.180 -0.012 8.64e-02 0.175 0.177 -0.003 6.21e-01
Prostate_Cancer LDpred2.Inf lassosum.10FCVal 0.135 0.180 -0.045 1.07e-25 0.129 0.177 -0.048 8.90e-09
Prostate_Cancer SBayesR.PseudoVal lassosum.10FCVal 0.176 0.180 -0.004 1.96e-01 0.171 0.177 -0.006 2.58e-01
Prostate_Cancer PRScs.MultiPRS lassosum.10FCVal 0.184 0.180 0.004 5.82e-01 0.173 0.177 -0.004 2.73e-01
Prostate_Cancer SBLUP.Inf lassosum.10FCVal 0.137 0.180 -0.043 3.00e-24 0.128 0.177 -0.049 4.50e-09
Prostate_Cancer lassosum.MultiPRS lassosum.10FCVal 0.187 0.180 0.007 3.14e-01 0.181 0.177 0.004 9.85e-02
Prostate_Cancer PRScs.10FCVal lassosum.10FCVal 0.181 0.180 0.001 6.91e-01 0.176 0.177 -0.001 8.38e-01
Prostate_Cancer LDpred2.MultiPRS lassosum.10FCVal 0.183 0.180 0.003 6.74e-01 0.175 0.177 -0.003 4.95e-01
Prostate_Cancer PRScs.PseudoVal lassosum.10FCVal 0.183 0.180 0.003 2.05e-01 0.172 0.177 -0.005 1.70e-01
Prostate_Cancer LDpred2.PseudoVal lassosum.10FCVal 0.139 0.180 -0.041 2.85e-23 0.133 0.177 -0.044 4.07e-08
Prostate_Cancer LDpred1.MultiPRS lassosum.10FCVal 0.164 0.180 -0.016 2.52e-02 0.149 0.177 -0.028 3.52e-06
Prostate_Cancer pT+clump.10FCVal lassosum.10FCVal 0.152 0.180 -0.028 9.78e-17 0.166 0.177 -0.011 8.84e-02
Prostate_Cancer All.MultiPRS lassosum.10FCVal 0.186 0.180 0.006 3.57e-01 0.181 0.177 0.004 3.70e-01
Prostate_Cancer LDpred1.Inf lassosum.10FCVal 0.143 0.180 -0.037 9.22e-21 0.133 0.177 -0.044 1.48e-08
Prostate_Cancer DBSLMM.PseudoVal lassosum.10FCVal 0.176 0.180 -0.004 1.64e-01 0.166 0.177 -0.012 2.45e-02
Prostate_Cancer LDpred1.10FCVal lassosum.10FCVal 0.165 0.180 -0.015 1.00e-06 0.152 0.177 -0.025 2.16e-05
Prostate_Cancer lassosum.PseudoVal lassosum.10FCVal 0.168 0.180 -0.012 3.97e-07 0.164 0.177 -0.014 3.45e-03
Prostate_Cancer LDpred2.10FCVal lassosum.10FCVal 0.183 0.180 0.003 8.51e-02 0.173 0.177 -0.004 2.60e-01
Prostate_Cancer LDpred2.10FCVal LDpred1.MultiPRS 0.183 0.164 0.019 7.19e-03 0.173 0.149 0.024 2.11e-06
Prostate_Cancer PRScs.PseudoVal LDpred1.MultiPRS 0.183 0.164 0.018 9.17e-03 0.172 0.149 0.022 9.32e-07
Prostate_Cancer LDpred2.Inf LDpred1.MultiPRS 0.135 0.164 -0.029 2.83e-05 0.129 0.149 -0.020 3.15e-04
Prostate_Cancer pT+clump.10FCVal LDpred1.MultiPRS 0.152 0.164 -0.012 8.13e-02 0.166 0.149 0.017 5.06e-02
Prostate_Cancer SBayesR.PseudoVal LDpred1.MultiPRS 0.176 0.164 0.012 8.65e-02 0.171 0.149 0.022 4.60e-03
Prostate_Cancer All.MultiPRS LDpred1.MultiPRS 0.186 0.164 0.022 1.53e-03 0.181 0.149 0.032 2.66e-08
Prostate_Cancer LDpred1.10FCVal LDpred1.MultiPRS 0.165 0.164 0.001 9.09e-01 0.152 0.149 0.003 1.50e-01
Prostate_Cancer LDpred1.MultiPRS LDpred1.MultiPRS 0.164 0.164 0.000 1.00e+00 0.149 0.149 0.000 1.00e+00
Prostate_Cancer PRScs.10FCVal LDpred1.MultiPRS 0.181 0.164 0.016 1.86e-02 0.176 0.149 0.027 1.05e-08
Prostate_Cancer lassosum.PseudoVal LDpred1.MultiPRS 0.168 0.164 0.004 5.82e-01 0.164 0.149 0.014 6.69e-02
Prostate_Cancer pT+clump.MultiPRS LDpred1.MultiPRS 0.168 0.164 0.004 5.91e-01 0.175 0.149 0.025 1.19e-04
Prostate_Cancer LDpred1.Inf LDpred1.MultiPRS 0.143 0.164 -0.021 2.09e-03 0.133 0.149 -0.016 1.67e-04
Prostate_Cancer lassosum.MultiPRS LDpred1.MultiPRS 0.187 0.164 0.023 7.43e-18 0.181 0.149 0.032 8.09e-10
Prostate_Cancer PRScs.MultiPRS LDpred1.MultiPRS 0.184 0.164 0.019 1.82e-17 0.173 0.149 0.023 1.75e-07
Prostate_Cancer lassosum.10FCVal LDpred1.MultiPRS 0.180 0.164 0.016 2.52e-02 0.177 0.149 0.028 3.52e-06
Prostate_Cancer LDpred2.PseudoVal LDpred1.MultiPRS 0.139 0.164 -0.025 2.59e-04 0.133 0.149 -0.016 2.07e-03
Prostate_Cancer DBSLMM.PseudoVal LDpred1.MultiPRS 0.176 0.164 0.012 8.52e-02 0.166 0.149 0.016 8.68e-04
Prostate_Cancer LDpred2.MultiPRS LDpred1.MultiPRS 0.183 0.164 0.018 7.53e-03 0.175 0.149 0.025 4.97e-08
Prostate_Cancer SBLUP.Inf LDpred1.MultiPRS 0.137 0.164 -0.028 7.05e-05 0.128 0.149 -0.021 1.20e-04
Prostate_Cancer All.MultiPRS LDpred1.Inf 0.186 0.143 0.043 3.80e-10 0.181 0.133 0.048 5.21e-11
Prostate_Cancer LDpred2.PseudoVal LDpred1.Inf 0.139 0.143 -0.004 7.93e-03 0.133 0.133 0.000 9.64e-01
Prostate_Cancer SBayesR.PseudoVal LDpred1.Inf 0.176 0.143 0.033 7.12e-12 0.171 0.133 0.038 7.33e-05
Prostate_Cancer LDpred2.MultiPRS LDpred1.Inf 0.183 0.143 0.040 8.54e-09 0.175 0.133 0.042 2.45e-10
Prostate_Cancer PRScs.PseudoVal LDpred1.Inf 0.183 0.143 0.039 1.16e-32 0.172 0.133 0.039 2.91e-09
Prostate_Cancer LDpred1.Inf LDpred1.Inf 0.143 0.143 0.000 1.00e+00 0.133 0.133 0.000 1.00e+00
Prostate_Cancer pT+clump.10FCVal LDpred1.Inf 0.152 0.143 0.009 6.60e-02 0.166 0.133 0.033 8.73e-04
Prostate_Cancer PRScs.MultiPRS LDpred1.Inf 0.184 0.143 0.041 4.16e-09 0.173 0.133 0.040 1.23e-09
Prostate_Cancer lassosum.PseudoVal LDpred1.Inf 0.168 0.143 0.025 5.16e-07 0.164 0.133 0.031 2.09e-03
Prostate_Cancer pT+clump.MultiPRS LDpred1.Inf 0.168 0.143 0.025 2.88e-04 0.175 0.133 0.042 7.25e-08
Prostate_Cancer LDpred1.MultiPRS LDpred1.Inf 0.164 0.143 0.021 2.09e-03 0.149 0.133 0.016 1.67e-04
Prostate_Cancer PRScs.10FCVal LDpred1.Inf 0.181 0.143 0.038 2.16e-28 0.176 0.133 0.043 1.26e-10
Prostate_Cancer LDpred2.Inf LDpred1.Inf 0.135 0.143 -0.008 1.28e-06 0.129 0.133 -0.004 2.10e-01
Prostate_Cancer SBLUP.Inf LDpred1.Inf 0.137 0.143 -0.006 5.10e-05 0.128 0.133 -0.005 1.15e-01
Prostate_Cancer DBSLMM.PseudoVal LDpred1.Inf 0.176 0.143 0.033 3.58e-26 0.166 0.133 0.033 1.87e-07
Prostate_Cancer lassosum.MultiPRS LDpred1.Inf 0.187 0.143 0.044 2.42e-10 0.181 0.133 0.048 2.52e-12
Prostate_Cancer LDpred1.10FCVal LDpred1.Inf 0.165 0.143 0.022 4.80e-22 0.152 0.133 0.019 4.30e-05
Prostate_Cancer lassosum.10FCVal LDpred1.Inf 0.180 0.143 0.037 9.22e-21 0.177 0.133 0.044 1.48e-08
Prostate_Cancer LDpred2.10FCVal LDpred1.Inf 0.183 0.143 0.040 5.13e-29 0.173 0.133 0.040 1.43e-08
Prostate_Cancer LDpred1.Inf LDpred1.10FCVal 0.143 0.165 -0.022 4.80e-22 0.133 0.152 -0.019 4.30e-05
Prostate_Cancer PRScs.MultiPRS LDpred1.10FCVal 0.184 0.165 0.019 7.42e-03 0.173 0.152 0.021 1.77e-06
Prostate_Cancer LDpred1.10FCVal LDpred1.10FCVal 0.165 0.165 0.000 1.00e+00 0.152 0.152 0.000 1.00e+00
Prostate_Cancer All.MultiPRS LDpred1.10FCVal 0.186 0.165 0.021 2.24e-03 0.181 0.152 0.029 2.30e-07
Prostate_Cancer SBayesR.PseudoVal LDpred1.10FCVal 0.176 0.165 0.011 3.98e-03 0.171 0.152 0.019 1.14e-02
Prostate_Cancer DBSLMM.PseudoVal LDpred1.10FCVal 0.176 0.165 0.011 7.93e-06 0.166 0.152 0.014 4.95e-03
Prostate_Cancer pT+clump.MultiPRS LDpred1.10FCVal 0.168 0.165 0.003 6.72e-01 0.175 0.152 0.023 5.77e-04
Prostate_Cancer lassosum.MultiPRS LDpred1.10FCVal 0.187 0.165 0.022 1.73e-03 0.181 0.152 0.029 1.16e-08
Prostate_Cancer PRScs.10FCVal LDpred1.10FCVal 0.181 0.165 0.016 4.90e-11 0.176 0.152 0.024 1.06e-07
Prostate_Cancer lassosum.10FCVal LDpred1.10FCVal 0.180 0.165 0.015 1.00e-06 0.177 0.152 0.025 2.16e-05
Prostate_Cancer SBLUP.Inf LDpred1.10FCVal 0.137 0.165 -0.028 1.14e-22 0.128 0.152 -0.024 4.07e-05
Prostate_Cancer LDpred2.PseudoVal LDpred1.10FCVal 0.139 0.165 -0.026 2.28e-20 0.133 0.152 -0.019 7.06e-04
Prostate_Cancer pT+clump.10FCVal LDpred1.10FCVal 0.152 0.165 -0.013 2.97e-03 0.166 0.152 0.014 9.75e-02
Prostate_Cancer LDpred2.MultiPRS LDpred1.10FCVal 0.183 0.165 0.018 1.06e-02 0.175 0.152 0.023 6.83e-07
Prostate_Cancer PRScs.PseudoVal LDpred1.10FCVal 0.183 0.165 0.017 4.15e-14 0.172 0.152 0.020 8.30e-06
Prostate_Cancer LDpred2.10FCVal LDpred1.10FCVal 0.183 0.165 0.018 1.00e-12 0.173 0.152 0.021 1.59e-05
Prostate_Cancer LDpred1.MultiPRS LDpred1.10FCVal 0.164 0.165 -0.001 9.09e-01 0.149 0.152 -0.003 1.50e-01
Prostate_Cancer LDpred2.Inf LDpred1.10FCVal 0.135 0.165 -0.030 8.30e-24 0.129 0.152 -0.023 1.11e-04
Prostate_Cancer lassosum.PseudoVal LDpred1.10FCVal 0.168 0.165 0.003 4.37e-01 0.164 0.152 0.012 1.26e-01
Prostate_Cancer LDpred1.Inf LDpred2.MultiPRS 0.143 0.183 -0.040 8.54e-09 0.133 0.175 -0.042 2.45e-10
Prostate_Cancer DBSLMM.PseudoVal LDpred2.MultiPRS 0.176 0.183 -0.007 3.46e-01 0.166 0.175 -0.009 2.19e-02
Prostate_Cancer SBLUP.Inf LDpred2.MultiPRS 0.137 0.183 -0.046 2.81e-11 0.128 0.175 -0.047 7.53e-11
Prostate_Cancer LDpred2.Inf LDpred2.MultiPRS 0.135 0.183 -0.048 6.33e-12 0.129 0.175 -0.046 8.86e-11
Prostate_Cancer pT+clump.10FCVal LDpred2.MultiPRS 0.152 0.183 -0.031 1.01e-05 0.166 0.175 -0.009 2.16e-01
Prostate_Cancer LDpred2.10FCVal LDpred2.MultiPRS 0.183 0.183 0.000 9.76e-01 0.173 0.175 -0.001 9.07e-02
Prostate_Cancer PRScs.PseudoVal LDpred2.MultiPRS 0.183 0.183 0.000 9.56e-01 0.172 0.175 -0.003 2.51e-01
Prostate_Cancer LDpred1.10FCVal LDpred2.MultiPRS 0.165 0.183 -0.018 1.06e-02 0.152 0.175 -0.023 6.83e-07
Prostate_Cancer All.MultiPRS LDpred2.MultiPRS 0.186 0.183 0.003 6.19e-01 0.181 0.175 0.006 9.08e-02
Prostate_Cancer SBayesR.PseudoVal LDpred2.MultiPRS 0.176 0.183 -0.007 3.43e-01 0.171 0.175 -0.004 4.72e-01
Prostate_Cancer lassosum.10FCVal LDpred2.MultiPRS 0.180 0.183 -0.003 6.74e-01 0.177 0.175 0.003 4.95e-01
Prostate_Cancer pT+clump.MultiPRS LDpred2.MultiPRS 0.168 0.183 -0.015 3.25e-02 0.175 0.175 0.000 9.80e-01
Prostate_Cancer lassosum.MultiPRS LDpred2.MultiPRS 0.187 0.183 0.004 5.56e-01 0.181 0.175 0.007 4.75e-02
Prostate_Cancer PRScs.10FCVal LDpred2.MultiPRS 0.181 0.183 -0.002 7.58e-01 0.176 0.175 0.002 4.86e-01
Prostate_Cancer PRScs.MultiPRS LDpred2.MultiPRS 0.184 0.183 0.001 8.95e-01 0.173 0.175 -0.002 4.40e-01
Prostate_Cancer lassosum.PseudoVal LDpred2.MultiPRS 0.168 0.183 -0.015 3.46e-02 0.164 0.175 -0.011 3.85e-02
Prostate_Cancer LDpred2.PseudoVal LDpred2.MultiPRS 0.139 0.183 -0.044 2.33e-10 0.133 0.175 -0.042 4.58e-10
Prostate_Cancer LDpred1.MultiPRS LDpred2.MultiPRS 0.164 0.183 -0.018 7.53e-03 0.149 0.175 -0.025 4.97e-08
Prostate_Cancer LDpred2.MultiPRS LDpred2.MultiPRS 0.183 0.183 0.000 1.00e+00 0.175 0.175 0.000 1.00e+00
Prostate_Cancer LDpred1.Inf LDpred2.10FCVal 0.143 0.183 -0.040 5.13e-29 0.133 0.173 -0.040 1.43e-08
Prostate_Cancer PRScs.MultiPRS LDpred2.10FCVal 0.184 0.183 0.001 9.19e-01 0.173 0.173 0.000 8.89e-01
Prostate_Cancer LDpred2.MultiPRS LDpred2.10FCVal 0.183 0.183 0.000 9.76e-01 0.175 0.173 0.001 9.07e-02
Prostate_Cancer PRScs.PseudoVal LDpred2.10FCVal 0.183 0.183 -0.001 6.50e-01 0.172 0.173 -0.001 5.88e-01
Prostate_Cancer LDpred2.10FCVal LDpred2.10FCVal 0.183 0.183 0.000 1.00e+00 0.173 0.173 0.000 1.00e+00
Prostate_Cancer lassosum.MultiPRS LDpred2.10FCVal 0.187 0.183 0.004 5.77e-01 0.181 0.173 0.008 1.60e-02
Prostate_Cancer LDpred1.10FCVal LDpred2.10FCVal 0.165 0.183 -0.018 1.00e-12 0.152 0.173 -0.021 1.59e-05
Prostate_Cancer All.MultiPRS LDpred2.10FCVal 0.186 0.183 0.003 6.39e-01 0.181 0.173 0.008 3.74e-02
Prostate_Cancer SBayesR.PseudoVal LDpred2.10FCVal 0.176 0.183 -0.007 7.85e-03 0.171 0.173 -0.002 6.45e-01
Prostate_Cancer DBSLMM.PseudoVal LDpred2.10FCVal 0.176 0.183 -0.007 1.39e-03 0.166 0.173 -0.008 7.03e-02
Prostate_Cancer pT+clump.MultiPRS LDpred2.10FCVal 0.168 0.183 -0.015 3.02e-02 0.175 0.173 0.001 8.03e-01
Prostate_Cancer lassosum.PseudoVal LDpred2.10FCVal 0.168 0.183 -0.015 3.31e-09 0.164 0.173 -0.010 5.28e-02
Prostate_Cancer PRScs.10FCVal LDpred2.10FCVal 0.181 0.183 -0.002 6.78e-02 0.176 0.173 0.003 1.97e-01
Prostate_Cancer lassosum.10FCVal LDpred2.10FCVal 0.180 0.183 -0.003 8.51e-02 0.177 0.173 0.004 2.60e-01
Prostate_Cancer SBLUP.Inf LDpred2.10FCVal 0.137 0.183 -0.046 1.04e-32 0.128 0.173 -0.045 5.06e-09
Prostate_Cancer LDpred2.PseudoVal LDpred2.10FCVal 0.139 0.183 -0.044 4.76e-33 0.133 0.173 -0.040 2.79e-08
Prostate_Cancer pT+clump.10FCVal LDpred2.10FCVal 0.152 0.183 -0.031 9.77e-19 0.166 0.173 -0.007 2.94e-01
Prostate_Cancer LDpred2.Inf LDpred2.10FCVal 0.135 0.183 -0.048 1.63e-35 0.129 0.173 -0.044 6.30e-09
Prostate_Cancer LDpred1.MultiPRS LDpred2.10FCVal 0.164 0.183 -0.019 7.19e-03 0.149 0.173 -0.024 2.11e-06
Prostate_Cancer lassosum.10FCVal LDpred2.PseudoVal 0.180 0.139 0.041 2.85e-23 0.177 0.133 0.044 4.07e-08
Prostate_Cancer SBLUP.Inf LDpred2.PseudoVal 0.137 0.139 -0.002 1.05e-02 0.128 0.133 -0.005 6.91e-03
Prostate_Cancer SBayesR.PseudoVal LDpred2.PseudoVal 0.176 0.139 0.037 5.49e-14 0.171 0.133 0.038 9.49e-05
Prostate_Cancer All.MultiPRS LDpred2.PseudoVal 0.186 0.139 0.047 7.98e-12 0.181 0.133 0.048 1.76e-10
Prostate_Cancer PRScs.PseudoVal LDpred2.PseudoVal 0.183 0.139 0.044 1.20e-35 0.172 0.133 0.039 1.26e-08
Prostate_Cancer lassosum.MultiPRS LDpred2.PseudoVal 0.187 0.139 0.048 4.82e-12 0.181 0.133 0.048 1.32e-11
Prostate_Cancer PRScs.MultiPRS LDpred2.PseudoVal 0.184 0.139 0.045 1.08e-10 0.173 0.133 0.040 6.15e-09
Prostate_Cancer LDpred2.MultiPRS LDpred2.PseudoVal 0.183 0.139 0.044 2.33e-10 0.175 0.133 0.042 4.58e-10
Prostate_Cancer PRScs.10FCVal LDpred2.PseudoVal 0.181 0.139 0.042 1.82e-31 0.176 0.133 0.044 6.22e-10
Prostate_Cancer LDpred2.PseudoVal LDpred2.PseudoVal 0.139 0.139 0.000 1.00e+00 0.133 0.133 0.000 1.00e+00
Prostate_Cancer pT+clump.MultiPRS LDpred2.PseudoVal 0.168 0.139 0.029 2.64e-05 0.175 0.133 0.042 1.48e-07
Prostate_Cancer pT+clump.10FCVal LDpred2.PseudoVal 0.152 0.139 0.013 1.03e-02 0.166 0.133 0.033 1.11e-03
Prostate_Cancer lassosum.PseudoVal LDpred2.PseudoVal 0.168 0.139 0.029 2.15e-08 0.164 0.133 0.031 2.83e-03
Prostate_Cancer LDpred1.Inf LDpred2.PseudoVal 0.143 0.139 0.004 7.93e-03 0.133 0.133 0.000 9.64e-01
Prostate_Cancer LDpred1.MultiPRS LDpred2.PseudoVal 0.164 0.139 0.025 2.59e-04 0.149 0.133 0.016 2.07e-03
Prostate_Cancer LDpred1.10FCVal LDpred2.PseudoVal 0.165 0.139 0.026 2.28e-20 0.152 0.133 0.019 7.06e-04
Prostate_Cancer LDpred2.Inf LDpred2.PseudoVal 0.135 0.139 -0.004 2.32e-33 0.129 0.133 -0.004 1.43e-09
Prostate_Cancer LDpred2.10FCVal LDpred2.PseudoVal 0.183 0.139 0.044 4.76e-33 0.173 0.133 0.040 2.79e-08
Prostate_Cancer DBSLMM.PseudoVal LDpred2.PseudoVal 0.176 0.139 0.037 1.19e-30 0.166 0.133 0.033 3.58e-07
Prostate_Cancer pT+clump.MultiPRS LDpred2.Inf 0.168 0.135 0.033 2.17e-06 0.175 0.129 0.045 2.43e-08
Prostate_Cancer lassosum.MultiPRS LDpred2.Inf 0.187 0.135 0.052 9.67e-14 0.181 0.129 0.052 2.18e-12
Prostate_Cancer SBayesR.PseudoVal LDpred2.Inf 0.176 0.135 0.041 8.05e-16 0.171 0.129 0.042 2.97e-05
Prostate_Cancer All.MultiPRS LDpred2.Inf 0.186 0.135 0.051 1.64e-13 0.181 0.129 0.052 2.66e-11
Prostate_Cancer SBLUP.Inf LDpred2.Inf 0.137 0.135 0.001 5.50e-02 0.128 0.129 -0.001 5.42e-01
Prostate_Cancer LDpred2.PseudoVal LDpred2.Inf 0.139 0.135 0.004 2.32e-33 0.133 0.129 0.004 1.43e-09
Prostate_Cancer PRScs.MultiPRS LDpred2.Inf 0.184 0.135 0.049 2.76e-12 0.173 0.129 0.044 1.17e-09
Prostate_Cancer LDpred2.MultiPRS LDpred2.Inf 0.183 0.135 0.048 6.33e-12 0.175 0.129 0.046 8.86e-11
Prostate_Cancer PRScs.10FCVal LDpred2.Inf 0.181 0.135 0.045 6.93e-34 0.176 0.129 0.047 1.46e-10
Prostate_Cancer LDpred1.Inf LDpred2.Inf 0.143 0.135 0.008 1.28e-06 0.133 0.129 0.004 2.10e-01
Prostate_Cancer LDpred1.MultiPRS LDpred2.Inf 0.164 0.135 0.029 2.83e-05 0.149 0.129 0.020 3.15e-04
Prostate_Cancer pT+clump.10FCVal LDpred2.Inf 0.152 0.135 0.017 1.31e-03 0.166 0.129 0.037 3.82e-04
Prostate_Cancer lassosum.PseudoVal LDpred2.Inf 0.168 0.135 0.033 8.14e-10 0.164 0.129 0.035 1.11e-03
Prostate_Cancer PRScs.PseudoVal LDpred2.Inf 0.183 0.135 0.047 4.26e-38 0.172 0.129 0.043 2.77e-09
Prostate_Cancer DBSLMM.PseudoVal LDpred2.Inf 0.176 0.135 0.041 3.72e-34 0.166 0.129 0.037 4.57e-08
Prostate_Cancer LDpred1.10FCVal LDpred2.Inf 0.165 0.135 0.030 8.30e-24 0.152 0.129 0.023 1.11e-04
Prostate_Cancer LDpred2.Inf LDpred2.Inf 0.135 0.135 0.000 1.00e+00 0.129 0.129 0.000 1.00e+00
Prostate_Cancer lassosum.10FCVal LDpred2.Inf 0.180 0.135 0.045 1.07e-25 0.177 0.129 0.048 8.90e-09
Prostate_Cancer LDpred2.10FCVal LDpred2.Inf 0.183 0.135 0.048 1.63e-35 0.173 0.129 0.044 6.30e-09
Prostate_Cancer PRScs.10FCVal PRScs.MultiPRS 0.181 0.184 -0.003 6.61e-01 0.176 0.173 0.004 3.09e-02
Prostate_Cancer LDpred1.10FCVal PRScs.MultiPRS 0.165 0.184 -0.019 7.42e-03 0.152 0.173 -0.021 1.77e-06
Prostate_Cancer lassosum.MultiPRS PRScs.MultiPRS 0.187 0.184 0.003 4.26e-02 0.181 0.173 0.008 6.54e-03
Prostate_Cancer LDpred2.MultiPRS PRScs.MultiPRS 0.183 0.184 -0.001 8.95e-01 0.175 0.173 0.002 4.40e-01
Prostate_Cancer All.MultiPRS PRScs.MultiPRS 0.186 0.184 0.003 7.14e-01 0.181 0.173 0.008 2.74e-02
Prostate_Cancer PRScs.PseudoVal PRScs.MultiPRS 0.183 0.184 -0.001 8.52e-01 0.172 0.173 -0.001 5.01e-01
Prostate_Cancer LDpred1.MultiPRS PRScs.MultiPRS 0.164 0.184 -0.019 1.82e-17 0.149 0.173 -0.023 1.75e-07
Prostate_Cancer pT+clump.MultiPRS PRScs.MultiPRS 0.168 0.184 -0.016 2.34e-02 0.175 0.173 0.002 7.50e-01
Prostate_Cancer lassosum.PseudoVal PRScs.MultiPRS 0.168 0.184 -0.016 2.52e-02 0.164 0.173 -0.009 7.34e-02
Prostate_Cancer SBayesR.PseudoVal PRScs.MultiPRS 0.176 0.184 -0.007 2.82e-01 0.171 0.173 -0.002 7.10e-01
Prostate_Cancer DBSLMM.PseudoVal PRScs.MultiPRS 0.176 0.184 -0.007 2.84e-01 0.166 0.173 -0.007 2.83e-02
Prostate_Cancer SBLUP.Inf PRScs.MultiPRS 0.137 0.184 -0.047 1.21e-11 0.128 0.173 -0.045 3.50e-10
Prostate_Cancer LDpred2.Inf PRScs.MultiPRS 0.135 0.184 -0.049 2.76e-12 0.129 0.173 -0.044 1.17e-09
Prostate_Cancer pT+clump.10FCVal PRScs.MultiPRS 0.152 0.184 -0.032 5.80e-06 0.166 0.173 -0.007 3.38e-01
Prostate_Cancer LDpred2.10FCVal PRScs.MultiPRS 0.183 0.184 -0.001 9.19e-01 0.173 0.173 0.000 8.89e-01
Prostate_Cancer lassosum.10FCVal PRScs.MultiPRS 0.180 0.184 -0.004 5.82e-01 0.177 0.173 0.004 2.73e-01
Prostate_Cancer LDpred2.PseudoVal PRScs.MultiPRS 0.139 0.184 -0.045 1.08e-10 0.133 0.173 -0.040 6.15e-09
Prostate_Cancer LDpred1.Inf PRScs.MultiPRS 0.143 0.184 -0.041 4.16e-09 0.133 0.173 -0.040 1.23e-09
Prostate_Cancer PRScs.MultiPRS PRScs.MultiPRS 0.184 0.184 0.000 1.00e+00 0.173 0.173 0.000 1.00e+00
Prostate_Cancer LDpred2.PseudoVal PRScs.10FCVal 0.139 0.181 -0.042 1.82e-31 0.133 0.176 -0.044 6.22e-10
Prostate_Cancer PRScs.10FCVal PRScs.10FCVal 0.181 0.181 0.000 1.00e+00 0.176 0.176 0.000 1.00e+00
Prostate_Cancer LDpred2.MultiPRS PRScs.10FCVal 0.183 0.181 0.002 7.58e-01 0.175 0.176 -0.002 4.86e-01
Prostate_Cancer pT+clump.MultiPRS PRScs.10FCVal 0.168 0.181 -0.013 6.77e-02 0.175 0.176 -0.002 7.36e-01
Prostate_Cancer LDpred1.Inf PRScs.10FCVal 0.143 0.181 -0.038 2.16e-28 0.133 0.176 -0.043 1.26e-10
Prostate_Cancer LDpred1.MultiPRS PRScs.10FCVal 0.164 0.181 -0.016 1.86e-02 0.149 0.176 -0.027 1.05e-08
Prostate_Cancer pT+clump.10FCVal PRScs.10FCVal 0.152 0.181 -0.028 1.19e-15 0.166 0.176 -0.010 1.38e-01
Prostate_Cancer lassosum.PseudoVal PRScs.10FCVal 0.168 0.181 -0.013 1.55e-06 0.164 0.176 -0.013 1.27e-02
Prostate_Cancer PRScs.PseudoVal PRScs.10FCVal 0.183 0.181 0.002 8.72e-02 0.172 0.176 -0.005 2.11e-02
Prostate_Cancer DBSLMM.PseudoVal PRScs.10FCVal 0.176 0.181 -0.004 1.62e-02 0.166 0.176 -0.011 3.19e-03
Prostate_Cancer SBLUP.Inf PRScs.10FCVal 0.137 0.181 -0.044 6.06e-32 0.128 0.176 -0.048 6.50e-11
Prostate_Cancer LDpred2.Inf PRScs.10FCVal 0.135 0.181 -0.045 6.93e-34 0.129 0.176 -0.047 1.46e-10
Prostate_Cancer lassosum.10FCVal PRScs.10FCVal 0.180 0.181 -0.001 6.91e-01 0.177 0.176 0.001 8.38e-01
Prostate_Cancer LDpred2.10FCVal PRScs.10FCVal 0.183 0.181 0.002 6.78e-02 0.173 0.176 -0.003 1.97e-01
Prostate_Cancer lassosum.MultiPRS PRScs.10FCVal 0.187 0.181 0.006 3.72e-01 0.181 0.176 0.005 1.58e-01
Prostate_Cancer LDpred1.10FCVal PRScs.10FCVal 0.165 0.181 -0.016 4.90e-11 0.152 0.176 -0.024 1.06e-07
Prostate_Cancer All.MultiPRS PRScs.10FCVal 0.186 0.181 0.006 4.20e-01 0.181 0.176 0.005 2.50e-01
Prostate_Cancer SBayesR.PseudoVal PRScs.10FCVal 0.176 0.181 -0.004 9.28e-02 0.171 0.176 -0.006 2.80e-01
Prostate_Cancer PRScs.MultiPRS PRScs.10FCVal 0.184 0.181 0.003 6.61e-01 0.173 0.176 -0.004 3.09e-02
Prostate_Cancer All.MultiPRS PRScs.PseudoVal 0.186 0.183 0.004 5.80e-01 0.181 0.172 0.009 1.53e-02
Prostate_Cancer pT+clump.MultiPRS PRScs.PseudoVal 0.168 0.183 -0.014 3.75e-02 0.175 0.172 0.003 6.19e-01
Prostate_Cancer LDpred2.PseudoVal PRScs.PseudoVal 0.139 0.183 -0.044 1.20e-35 0.133 0.172 -0.039 1.26e-08
Prostate_Cancer SBayesR.PseudoVal PRScs.PseudoVal 0.176 0.183 -0.006 2.28e-02 0.171 0.172 -0.001 8.70e-01
Prostate_Cancer LDpred2.MultiPRS PRScs.PseudoVal 0.183 0.183 0.000 9.56e-01 0.175 0.172 0.003 2.51e-01
Prostate_Cancer SBLUP.Inf PRScs.PseudoVal 0.137 0.183 -0.046 4.43e-36 0.128 0.172 -0.044 1.18e-09
Prostate_Cancer LDpred1.Inf PRScs.PseudoVal 0.143 0.183 -0.039 1.16e-32 0.133 0.172 -0.039 2.91e-09
Prostate_Cancer PRScs.10FCVal PRScs.PseudoVal 0.181 0.183 -0.002 8.72e-02 0.176 0.172 0.005 2.11e-02
Prostate_Cancer LDpred2.Inf PRScs.PseudoVal 0.135 0.183 -0.047 4.26e-38 0.129 0.172 -0.043 2.77e-09
Prostate_Cancer PRScs.PseudoVal PRScs.PseudoVal 0.183 0.183 0.000 1.00e+00 0.172 0.172 0.000 1.00e+00
Prostate_Cancer LDpred2.10FCVal PRScs.PseudoVal 0.183 0.183 0.001 6.50e-01 0.173 0.172 0.001 5.88e-01
Prostate_Cancer pT+clump.10FCVal PRScs.PseudoVal 0.152 0.183 -0.030 5.41e-17 0.166 0.172 -0.006 4.21e-01
Prostate_Cancer PRScs.MultiPRS PRScs.PseudoVal 0.184 0.183 0.001 8.52e-01 0.173 0.172 0.001 5.01e-01
Prostate_Cancer lassosum.PseudoVal PRScs.PseudoVal 0.168 0.183 -0.014 1.14e-07 0.164 0.172 -0.008 1.26e-01
Prostate_Cancer lassosum.10FCVal PRScs.PseudoVal 0.180 0.183 -0.003 2.05e-01 0.177 0.172 0.005 1.70e-01
Prostate_Cancer LDpred1.MultiPRS PRScs.PseudoVal 0.164 0.183 -0.018 9.17e-03 0.149 0.172 -0.022 9.32e-07
Prostate_Cancer lassosum.MultiPRS PRScs.PseudoVal 0.187 0.183 0.004 5.21e-01 0.181 0.172 0.009 4.79e-03
Prostate_Cancer LDpred1.10FCVal PRScs.PseudoVal 0.165 0.183 -0.017 4.15e-14 0.152 0.172 -0.020 8.30e-06
Prostate_Cancer DBSLMM.PseudoVal PRScs.PseudoVal 0.176 0.183 -0.006 5.43e-04 0.166 0.172 -0.006 8.06e-02
Prostate_Cancer All.MultiPRS pT+clump.MultiPRS 0.186 0.168 0.018 8.51e-03 0.181 0.175 0.007 2.34e-01
Prostate_Cancer SBayesR.PseudoVal pT+clump.MultiPRS 0.176 0.168 0.008 2.36e-01 0.171 0.175 -0.004 5.68e-01
Prostate_Cancer LDpred1.MultiPRS pT+clump.MultiPRS 0.164 0.168 -0.004 5.91e-01 0.149 0.175 -0.025 1.19e-04
Prostate_Cancer pT+clump.MultiPRS pT+clump.MultiPRS 0.168 0.168 0.000 1.00e+00 0.175 0.175 0.000 1.00e+00
Prostate_Cancer lassosum.PseudoVal pT+clump.MultiPRS 0.168 0.168 0.000 9.88e-01 0.164 0.175 -0.011 9.03e-02
Prostate_Cancer PRScs.10FCVal pT+clump.MultiPRS 0.181 0.168 0.013 6.77e-02 0.176 0.175 0.002 7.36e-01
Prostate_Cancer DBSLMM.PseudoVal pT+clump.MultiPRS 0.176 0.168 0.008 2.33e-01 0.166 0.175 -0.009 1.02e-01
Prostate_Cancer SBLUP.Inf pT+clump.MultiPRS 0.137 0.168 -0.031 6.02e-06 0.128 0.175 -0.046 1.05e-08
Prostate_Cancer LDpred2.Inf pT+clump.MultiPRS 0.135 0.168 -0.033 2.17e-06 0.129 0.175 -0.045 2.43e-08
Prostate_Cancer pT+clump.10FCVal pT+clump.MultiPRS 0.152 0.168 -0.016 2.19e-02 0.166 0.175 -0.008 5.70e-02
Prostate_Cancer LDpred2.10FCVal pT+clump.MultiPRS 0.183 0.168 0.015 3.02e-02 0.173 0.175 -0.001 8.03e-01
Prostate_Cancer PRScs.PseudoVal pT+clump.MultiPRS 0.183 0.168 0.014 3.75e-02 0.172 0.175 -0.003 6.19e-01
Prostate_Cancer LDpred1.10FCVal pT+clump.MultiPRS 0.165 0.168 -0.003 6.72e-01 0.152 0.175 -0.023 5.77e-04
Prostate_Cancer LDpred1.Inf pT+clump.MultiPRS 0.143 0.168 -0.025 2.88e-04 0.133 0.175 -0.042 7.25e-08
Prostate_Cancer PRScs.MultiPRS pT+clump.MultiPRS 0.184 0.168 0.016 2.34e-02 0.173 0.175 -0.002 7.50e-01
Prostate_Cancer lassosum.10FCVal pT+clump.MultiPRS 0.180 0.168 0.012 8.64e-02 0.177 0.175 0.003 6.21e-01
Prostate_Cancer LDpred2.PseudoVal pT+clump.MultiPRS 0.139 0.168 -0.029 2.64e-05 0.133 0.175 -0.042 1.48e-07
Prostate_Cancer lassosum.MultiPRS pT+clump.MultiPRS 0.187 0.168 0.019 6.46e-03 0.181 0.175 0.007 1.86e-01
Prostate_Cancer LDpred2.MultiPRS pT+clump.MultiPRS 0.183 0.168 0.015 3.25e-02 0.175 0.175 0.000 9.80e-01
Prostate_Cancer LDpred2.10FCVal pT+clump.10FCVal 0.183 0.152 0.031 9.77e-19 0.173 0.166 0.007 2.94e-01
Prostate_Cancer pT+clump.MultiPRS pT+clump.10FCVal 0.168 0.152 0.016 2.19e-02 0.175 0.166 0.008 5.70e-02
Prostate_Cancer LDpred2.Inf pT+clump.10FCVal 0.135 0.152 -0.017 1.31e-03 0.129 0.166 -0.037 3.82e-04
Prostate_Cancer SBayesR.PseudoVal pT+clump.10FCVal 0.176 0.152 0.024 1.05e-14 0.171 0.166 0.005 4.40e-01
Prostate_Cancer PRScs.MultiPRS pT+clump.10FCVal 0.184 0.152 0.032 5.80e-06 0.173 0.166 0.007 3.38e-01
Prostate_Cancer SBLUP.Inf pT+clump.10FCVal 0.137 0.152 -0.015 3.57e-03 0.128 0.166 -0.038 3.00e-04
Prostate_Cancer lassosum.MultiPRS pT+clump.10FCVal 0.187 0.152 0.035 5.96e-07 0.181 0.166 0.015 2.26e-02
Prostate_Cancer PRScs.10FCVal pT+clump.10FCVal 0.181 0.152 0.028 1.19e-15 0.176 0.166 0.010 1.38e-01
Prostate_Cancer LDpred2.MultiPRS pT+clump.10FCVal 0.183 0.152 0.031 1.01e-05 0.175 0.166 0.009 2.16e-01
Prostate_Cancer lassosum.10FCVal pT+clump.10FCVal 0.180 0.152 0.028 9.78e-17 0.177 0.166 0.011 8.84e-02
Prostate_Cancer LDpred2.PseudoVal pT+clump.10FCVal 0.139 0.152 -0.013 1.03e-02 0.133 0.166 -0.033 1.11e-03
Prostate_Cancer LDpred1.MultiPRS pT+clump.10FCVal 0.164 0.152 0.012 8.13e-02 0.149 0.166 -0.017 5.06e-02
Prostate_Cancer pT+clump.10FCVal pT+clump.10FCVal 0.152 0.152 0.000 1.00e+00 0.166 0.166 0.000 1.00e+00
Prostate_Cancer All.MultiPRS pT+clump.10FCVal 0.186 0.152 0.034 8.40e-07 0.181 0.166 0.015 2.88e-02
Prostate_Cancer LDpred1.Inf pT+clump.10FCVal 0.143 0.152 -0.009 6.60e-02 0.133 0.166 -0.033 8.73e-04
Prostate_Cancer DBSLMM.PseudoVal pT+clump.10FCVal 0.176 0.152 0.024 7.26e-11 0.166 0.166 -0.001 9.45e-01
Prostate_Cancer LDpred1.10FCVal pT+clump.10FCVal 0.165 0.152 0.013 2.97e-03 0.152 0.166 -0.014 9.75e-02
Prostate_Cancer lassosum.PseudoVal pT+clump.10FCVal 0.168 0.152 0.016 9.05e-08 0.164 0.166 -0.002 6.78e-01
Prostate_Cancer PRScs.PseudoVal pT+clump.10FCVal 0.183 0.152 0.030 5.41e-17 0.172 0.166 0.006 4.21e-01
Prostate_Cancer pT+clump.MultiPRS SBayesR.PseudoVal 0.168 0.176 -0.008 2.36e-01 0.175 0.171 0.004 5.68e-01
Prostate_Cancer LDpred1.10FCVal SBayesR.PseudoVal 0.165 0.176 -0.011 3.98e-03 0.152 0.171 -0.019 1.14e-02
Prostate_Cancer PRScs.10FCVal SBayesR.PseudoVal 0.181 0.176 0.004 9.28e-02 0.176 0.171 0.006 2.80e-01
Prostate_Cancer LDpred2.10FCVal SBayesR.PseudoVal 0.183 0.176 0.007 7.85e-03 0.173 0.171 0.002 6.45e-01
Prostate_Cancer lassosum.10FCVal SBayesR.PseudoVal 0.180 0.176 0.004 1.96e-01 0.177 0.171 0.006 2.58e-01
Prostate_Cancer LDpred2.PseudoVal SBayesR.PseudoVal 0.139 0.176 -0.037 5.49e-14 0.133 0.171 -0.038 9.49e-05
Prostate_Cancer lassosum.MultiPRS SBayesR.PseudoVal 0.187 0.176 0.011 1.26e-01 0.181 0.171 0.010 5.96e-02
Prostate_Cancer LDpred2.MultiPRS SBayesR.PseudoVal 0.183 0.176 0.007 3.43e-01 0.175 0.171 0.004 4.72e-01
Prostate_Cancer All.MultiPRS SBayesR.PseudoVal 0.186 0.176 0.010 1.48e-01 0.181 0.171 0.010 2.71e-02
Prostate_Cancer PRScs.PseudoVal SBayesR.PseudoVal 0.183 0.176 0.006 2.28e-02 0.172 0.171 0.001 8.70e-01
Prostate_Cancer LDpred1.MultiPRS SBayesR.PseudoVal 0.164 0.176 -0.012 8.65e-02 0.149 0.171 -0.022 4.60e-03
Prostate_Cancer pT+clump.10FCVal SBayesR.PseudoVal 0.152 0.176 -0.024 1.05e-14 0.166 0.171 -0.005 4.40e-01
Prostate_Cancer lassosum.PseudoVal SBayesR.PseudoVal 0.168 0.176 -0.008 3.42e-04 0.164 0.171 -0.007 9.86e-02
Prostate_Cancer SBayesR.PseudoVal SBayesR.PseudoVal 0.176 0.176 0.000 1.00e+00 0.171 0.171 0.000 1.00e+00
Prostate_Cancer DBSLMM.PseudoVal SBayesR.PseudoVal 0.176 0.176 0.000 9.91e-01 0.166 0.171 -0.005 3.65e-01
Prostate_Cancer SBLUP.Inf SBayesR.PseudoVal 0.137 0.176 -0.040 1.15e-14 0.128 0.171 -0.043 2.19e-05
Prostate_Cancer LDpred2.Inf SBayesR.PseudoVal 0.135 0.176 -0.041 8.05e-16 0.129 0.171 -0.042 2.97e-05
Prostate_Cancer LDpred1.Inf SBayesR.PseudoVal 0.143 0.176 -0.033 7.12e-12 0.133 0.171 -0.038 7.33e-05
Prostate_Cancer PRScs.MultiPRS SBayesR.PseudoVal 0.184 0.176 0.007 2.82e-01 0.173 0.171 0.002 7.10e-01
Prostate_Cancer LDpred2.10FCVal SBLUP.Inf 0.183 0.137 0.046 1.04e-32 0.173 0.128 0.045 5.06e-09
Prostate_Cancer PRScs.PseudoVal SBLUP.Inf 0.183 0.137 0.046 4.43e-36 0.172 0.128 0.044 1.18e-09
Prostate_Cancer LDpred1.10FCVal SBLUP.Inf 0.165 0.137 0.028 1.14e-22 0.152 0.128 0.024 4.07e-05
Prostate_Cancer LDpred2.Inf SBLUP.Inf 0.135 0.137 -0.001 5.50e-02 0.129 0.128 0.001 5.42e-01
Prostate_Cancer SBayesR.PseudoVal SBLUP.Inf 0.176 0.137 0.040 1.15e-14 0.171 0.128 0.043 2.19e-05
Prostate_Cancer lassosum.10FCVal SBLUP.Inf 0.180 0.137 0.043 3.00e-24 0.177 0.128 0.049 4.50e-09
Prostate_Cancer pT+clump.MultiPRS SBLUP.Inf 0.168 0.137 0.031 6.02e-06 0.175 0.128 0.046 1.05e-08
Prostate_Cancer lassosum.MultiPRS SBLUP.Inf 0.187 0.137 0.050 4.67e-13 0.181 0.128 0.053 6.18e-13
Prostate_Cancer PRScs.10FCVal SBLUP.Inf 0.181 0.137 0.044 6.06e-32 0.176 0.128 0.048 6.50e-11
Prostate_Cancer PRScs.MultiPRS SBLUP.Inf 0.184 0.137 0.047 1.21e-11 0.173 0.128 0.045 3.50e-10
Prostate_Cancer LDpred1.MultiPRS SBLUP.Inf 0.164 0.137 0.028 7.05e-05 0.149 0.128 0.021 1.20e-04
Prostate_Cancer LDpred2.PseudoVal SBLUP.Inf 0.139 0.137 0.002 1.05e-02 0.133 0.128 0.005 6.91e-03
Prostate_Cancer LDpred1.Inf SBLUP.Inf 0.143 0.137 0.006 5.10e-05 0.133 0.128 0.005 1.15e-01
Prostate_Cancer LDpred2.MultiPRS SBLUP.Inf 0.183 0.137 0.046 2.81e-11 0.175 0.128 0.047 7.53e-11
Prostate_Cancer All.MultiPRS SBLUP.Inf 0.186 0.137 0.050 8.19e-13 0.181 0.128 0.053 1.01e-11
Prostate_Cancer SBLUP.Inf SBLUP.Inf 0.137 0.137 0.000 1.00e+00 0.128 0.128 0.000 1.00e+00
Prostate_Cancer DBSLMM.PseudoVal SBLUP.Inf 0.176 0.137 0.040 6.96e-33 0.166 0.128 0.038 1.26e-08
Prostate_Cancer pT+clump.10FCVal SBLUP.Inf 0.152 0.137 0.015 3.57e-03 0.166 0.128 0.038 3.00e-04
Prostate_Cancer lassosum.PseudoVal SBLUP.Inf 0.168 0.137 0.031 4.95e-09 0.164 0.128 0.036 8.48e-04
Breast_Cancer LDpred2.PseudoVal All.MultiPRS 0.169 0.228 -0.059 5.12e-19 0.161 0.215 -0.054 3.92e-14
Breast_Cancer pT+clump.10FCVal All.MultiPRS 0.179 0.228 -0.049 1.19e-13 0.167 0.215 -0.048 4.23e-13
Breast_Cancer LDpred2.MultiPRS All.MultiPRS 0.224 0.228 -0.003 6.28e-01 0.211 0.215 -0.004 5.16e-02
Breast_Cancer PRScs.PseudoVal All.MultiPRS 0.220 0.228 -0.007 2.70e-01 0.208 0.215 -0.007 1.82e-02
Breast_Cancer LDpred1.Inf All.MultiPRS 0.172 0.228 -0.056 2.56e-17 0.162 0.215 -0.053 3.87e-14
Breast_Cancer PRScs.MultiPRS All.MultiPRS 0.222 0.228 -0.006 4.18e-01 0.210 0.215 -0.005 1.02e-01
Breast_Cancer LDpred2.Inf All.MultiPRS 0.168 0.228 -0.060 1.35e-19 0.160 0.215 -0.055 3.36e-14
Breast_Cancer lassosum.10FCVal All.MultiPRS 0.219 0.228 -0.008 1.94e-01 0.199 0.215 -0.016 4.48e-06
Breast_Cancer LDpred2.10FCVal All.MultiPRS 0.223 0.228 -0.004 5.31e-01 0.211 0.215 -0.004 1.28e-01
Breast_Cancer lassosum.MultiPRS All.MultiPRS 0.225 0.228 -0.002 7.28e-01 0.212 0.215 -0.003 1.60e-01
Breast_Cancer LDpred1.10FCVal All.MultiPRS 0.201 0.228 -0.027 4.03e-05 0.186 0.215 -0.029 1.35e-08
Breast_Cancer All.MultiPRS All.MultiPRS 0.228 0.228 0.000 1.00e+00 0.215 0.215 0.000 1.00e+00
Breast_Cancer SBayesR.PseudoVal All.MultiPRS 0.221 0.228 -0.007 3.04e-01 0.205 0.215 -0.010 2.21e-03
Breast_Cancer LDpred1.MultiPRS All.MultiPRS 0.211 0.228 -0.016 1.08e-15 0.195 0.215 -0.021 7.66e-07
Breast_Cancer pT+clump.MultiPRS All.MultiPRS 0.200 0.228 -0.027 5.53e-05 0.188 0.215 -0.027 6.94e-08
Breast_Cancer lassosum.PseudoVal All.MultiPRS 0.217 0.228 -0.010 1.07e-01 0.199 0.215 -0.016 1.85e-05
Breast_Cancer PRScs.10FCVal All.MultiPRS 0.220 0.228 -0.008 2.27e-01 0.207 0.215 -0.008 1.16e-02
Breast_Cancer DBSLMM.PseudoVal All.MultiPRS 0.217 0.228 -0.010 1.21e-01 0.211 0.215 -0.004 2.21e-01
Breast_Cancer SBLUP.Inf All.MultiPRS 0.168 0.228 -0.060 1.18e-19 0.158 0.215 -0.057 6.47e-15
Breast_Cancer SBayesR.PseudoVal DBSLMM.PseudoVal 0.221 0.217 0.003 1.87e-01 0.205 0.211 -0.006 2.63e-01
Breast_Cancer LDpred2.Inf DBSLMM.PseudoVal 0.168 0.217 -0.050 4.35e-63 0.160 0.211 -0.051 2.59e-17
Breast_Cancer pT+clump.10FCVal DBSLMM.PseudoVal 0.179 0.217 -0.039 1.13e-26 0.167 0.211 -0.044 1.63e-09
Breast_Cancer PRScs.10FCVal DBSLMM.PseudoVal 0.220 0.217 0.002 2.02e-01 0.207 0.211 -0.004 2.99e-01
Breast_Cancer PRScs.PseudoVal DBSLMM.PseudoVal 0.220 0.217 0.003 8.35e-02 0.208 0.211 -0.003 3.66e-01
Breast_Cancer pT+clump.MultiPRS DBSLMM.PseudoVal 0.200 0.217 -0.017 1.10e-02 0.188 0.211 -0.023 3.20e-06
Breast_Cancer LDpred1.Inf DBSLMM.PseudoVal 0.172 0.217 -0.046 7.43e-56 0.162 0.211 -0.049 4.73e-17
Breast_Cancer lassosum.MultiPRS DBSLMM.PseudoVal 0.225 0.217 0.008 2.57e-01 0.212 0.211 0.001 7.62e-01
Breast_Cancer LDpred2.10FCVal DBSLMM.PseudoVal 0.223 0.217 0.006 2.79e-03 0.211 0.211 0.000 9.43e-01
Breast_Cancer lassosum.10FCVal DBSLMM.PseudoVal 0.219 0.217 0.002 5.12e-01 0.199 0.211 -0.012 2.03e-02
Breast_Cancer LDpred1.10FCVal DBSLMM.PseudoVal 0.201 0.217 -0.017 6.72e-14 0.186 0.211 -0.025 5.79e-08
Breast_Cancer LDpred1.MultiPRS DBSLMM.PseudoVal 0.211 0.217 -0.006 3.30e-01 0.195 0.211 -0.016 4.98e-04
Breast_Cancer PRScs.MultiPRS DBSLMM.PseudoVal 0.222 0.217 0.005 5.06e-01 0.210 0.211 0.000 9.39e-01
Breast_Cancer All.MultiPRS DBSLMM.PseudoVal 0.228 0.217 0.010 1.21e-01 0.215 0.211 0.004 2.21e-01
Breast_Cancer LDpred2.PseudoVal DBSLMM.PseudoVal 0.169 0.217 -0.049 7.14e-62 0.161 0.211 -0.050 2.83e-17
Breast_Cancer DBSLMM.PseudoVal DBSLMM.PseudoVal 0.217 0.217 0.000 1.00e+00 0.211 0.211 0.000 1.00e+00
Breast_Cancer LDpred2.MultiPRS DBSLMM.PseudoVal 0.224 0.217 0.007 3.19e-01 0.211 0.211 0.000 9.77e-01
Breast_Cancer lassosum.PseudoVal DBSLMM.PseudoVal 0.217 0.217 0.000 8.85e-01 0.199 0.211 -0.012 4.09e-02
Breast_Cancer SBLUP.Inf DBSLMM.PseudoVal 0.168 0.217 -0.050 7.26e-65 0.158 0.211 -0.052 6.94e-19
Breast_Cancer SBayesR.PseudoVal lassosum.MultiPRS 0.221 0.225 -0.004 5.27e-01 0.205 0.212 -0.007 6.17e-02
Breast_Cancer LDpred2.10FCVal lassosum.MultiPRS 0.223 0.225 -0.002 8.02e-01 0.211 0.212 -0.001 7.83e-01
Breast_Cancer LDpred1.10FCVal lassosum.MultiPRS 0.201 0.225 -0.024 3.39e-04 0.186 0.212 -0.026 1.03e-06
Breast_Cancer LDpred2.Inf lassosum.MultiPRS 0.168 0.225 -0.057 4.78e-17 0.160 0.212 -0.052 1.88e-12
Breast_Cancer PRScs.10FCVal lassosum.MultiPRS 0.220 0.225 -0.005 4.20e-01 0.207 0.212 -0.005 1.14e-01
Breast_Cancer PRScs.MultiPRS lassosum.MultiPRS 0.222 0.225 -0.003 6.40e-01 0.210 0.212 -0.001 6.00e-01
Breast_Cancer pT+clump.MultiPRS lassosum.MultiPRS 0.200 0.225 -0.025 2.44e-04 0.188 0.212 -0.024 7.15e-07
Breast_Cancer lassosum.MultiPRS lassosum.MultiPRS 0.225 0.225 0.000 1.00e+00 0.212 0.212 0.000 1.00e+00
Breast_Cancer lassosum.PseudoVal lassosum.MultiPRS 0.217 0.225 -0.008 2.32e-01 0.199 0.212 -0.013 4.60e-05
Breast_Cancer LDpred2.MultiPRS lassosum.MultiPRS 0.224 0.225 -0.001 5.62e-01 0.211 0.212 -0.001 6.85e-01
Breast_Cancer LDpred1.MultiPRS lassosum.MultiPRS 0.211 0.225 -0.014 3.87e-02 0.195 0.212 -0.017 1.49e-04
Breast_Cancer LDpred2.PseudoVal lassosum.MultiPRS 0.169 0.225 -0.056 1.58e-16 0.161 0.212 -0.051 2.04e-12
Breast_Cancer LDpred1.Inf lassosum.MultiPRS 0.172 0.225 -0.053 5.98e-15 0.162 0.212 -0.050 2.69e-12
Breast_Cancer pT+clump.10FCVal lassosum.MultiPRS 0.179 0.225 -0.047 9.73e-12 0.167 0.212 -0.045 3.14e-12
Breast_Cancer lassosum.10FCVal lassosum.MultiPRS 0.219 0.225 -0.006 3.71e-01 0.199 0.212 -0.013 4.75e-06
Breast_Cancer SBLUP.Inf lassosum.MultiPRS 0.168 0.225 -0.057 4.39e-17 0.158 0.212 -0.054 2.59e-13
Breast_Cancer DBSLMM.PseudoVal lassosum.MultiPRS 0.217 0.225 -0.008 2.57e-01 0.211 0.212 -0.001 7.62e-01
Breast_Cancer All.MultiPRS lassosum.MultiPRS 0.228 0.225 0.002 7.28e-01 0.215 0.212 0.003 1.60e-01
Breast_Cancer PRScs.PseudoVal lassosum.MultiPRS 0.220 0.225 -0.005 4.81e-01 0.208 0.212 -0.004 1.76e-01
Breast_Cancer LDpred1.Inf lassosum.PseudoVal 0.172 0.217 -0.045 8.22e-25 0.162 0.199 -0.037 2.34e-05
Breast_Cancer PRScs.10FCVal lassosum.PseudoVal 0.220 0.217 0.003 2.11e-01 0.207 0.199 0.008 6.16e-02
Breast_Cancer LDpred2.MultiPRS lassosum.PseudoVal 0.224 0.217 0.007 2.90e-01 0.211 0.199 0.011 4.64e-03
Breast_Cancer lassosum.PseudoVal lassosum.PseudoVal 0.217 0.217 0.000 1.00e+00 0.199 0.199 0.000 1.00e+00
Breast_Cancer PRScs.PseudoVal lassosum.PseudoVal 0.220 0.217 0.003 1.32e-01 0.208 0.199 0.008 5.69e-02
Breast_Cancer DBSLMM.PseudoVal lassosum.PseudoVal 0.217 0.217 0.000 8.85e-01 0.211 0.199 0.012 4.09e-02
Breast_Cancer SBLUP.Inf lassosum.PseudoVal 0.168 0.217 -0.049 1.43e-27 0.158 0.199 -0.041 7.57e-06
Breast_Cancer LDpred2.Inf lassosum.PseudoVal 0.168 0.217 -0.049 1.60e-27 0.160 0.199 -0.039 1.85e-05
Breast_Cancer pT+clump.10FCVal lassosum.PseudoVal 0.179 0.217 -0.038 5.41e-37 0.167 0.199 -0.032 7.03e-08
Breast_Cancer LDpred2.10FCVal lassosum.PseudoVal 0.223 0.217 0.006 2.21e-03 0.211 0.199 0.012 4.64e-03
Breast_Cancer lassosum.MultiPRS lassosum.PseudoVal 0.225 0.217 0.008 2.32e-01 0.212 0.199 0.013 4.60e-05
Breast_Cancer LDpred1.10FCVal lassosum.PseudoVal 0.201 0.217 -0.016 1.79e-06 0.186 0.199 -0.013 5.42e-02
Breast_Cancer All.MultiPRS lassosum.PseudoVal 0.228 0.217 0.010 1.07e-01 0.215 0.199 0.016 1.85e-05
Breast_Cancer SBayesR.PseudoVal lassosum.PseudoVal 0.221 0.217 0.004 3.57e-02 0.205 0.199 0.006 1.10e-01
Breast_Cancer lassosum.10FCVal lassosum.PseudoVal 0.219 0.217 0.002 1.14e-01 0.199 0.199 0.000 9.41e-01
Breast_Cancer pT+clump.MultiPRS lassosum.PseudoVal 0.200 0.217 -0.017 1.31e-02 0.188 0.199 -0.012 3.21e-02
Breast_Cancer LDpred2.PseudoVal lassosum.PseudoVal 0.169 0.217 -0.048 4.77e-27 0.161 0.199 -0.039 2.02e-05
Breast_Cancer LDpred1.MultiPRS lassosum.PseudoVal 0.211 0.217 -0.006 3.64e-01 0.195 0.199 -0.005 4.05e-01
Breast_Cancer PRScs.MultiPRS lassosum.PseudoVal 0.222 0.217 0.005 4.69e-01 0.210 0.199 0.011 3.74e-03
Breast_Cancer lassosum.10FCVal lassosum.10FCVal 0.219 0.219 0.000 1.00e+00 0.199 0.199 0.000 1.00e+00
Breast_Cancer pT+clump.MultiPRS lassosum.10FCVal 0.200 0.219 -0.019 5.40e-03 0.188 0.199 -0.011 2.53e-02
Breast_Cancer LDpred2.Inf lassosum.10FCVal 0.168 0.219 -0.051 1.14e-40 0.160 0.199 -0.039 4.70e-07
Breast_Cancer SBayesR.PseudoVal lassosum.10FCVal 0.221 0.219 0.002 4.32e-01 0.205 0.199 0.006 1.88e-01
Breast_Cancer PRScs.MultiPRS lassosum.10FCVal 0.222 0.219 0.003 6.71e-01 0.210 0.199 0.011 9.27e-04
Breast_Cancer SBLUP.Inf lassosum.10FCVal 0.168 0.219 -0.051 5.81e-41 0.158 0.199 -0.041 1.27e-07
Breast_Cancer lassosum.MultiPRS lassosum.10FCVal 0.225 0.219 0.006 3.71e-01 0.212 0.199 0.013 4.75e-06
Breast_Cancer PRScs.10FCVal lassosum.10FCVal 0.220 0.219 0.001 7.42e-01 0.207 0.199 0.008 2.54e-02
Breast_Cancer LDpred2.MultiPRS lassosum.10FCVal 0.224 0.219 0.005 4.48e-01 0.211 0.199 0.012 1.56e-03
Breast_Cancer PRScs.PseudoVal lassosum.10FCVal 0.220 0.219 0.001 4.82e-01 0.208 0.199 0.009 1.94e-02
Breast_Cancer LDpred2.PseudoVal lassosum.10FCVal 0.169 0.219 -0.050 4.09e-40 0.161 0.199 -0.038 5.08e-07
Breast_Cancer LDpred1.MultiPRS lassosum.10FCVal 0.211 0.219 -0.008 2.21e-01 0.195 0.199 -0.004 3.53e-01
Breast_Cancer pT+clump.10FCVal lassosum.10FCVal 0.179 0.219 -0.040 3.58e-34 0.167 0.199 -0.032 1.31e-06
Breast_Cancer All.MultiPRS lassosum.10FCVal 0.228 0.219 0.008 1.94e-01 0.215 0.199 0.016 4.48e-06
Breast_Cancer LDpred1.Inf lassosum.10FCVal 0.172 0.219 -0.047 6.72e-37 0.162 0.199 -0.037 6.56e-07
Breast_Cancer DBSLMM.PseudoVal lassosum.10FCVal 0.217 0.219 -0.002 5.12e-01 0.211 0.199 0.012 2.03e-02
Breast_Cancer LDpred1.10FCVal lassosum.10FCVal 0.201 0.219 -0.018 5.81e-11 0.186 0.199 -0.013 2.09e-02
Breast_Cancer lassosum.PseudoVal lassosum.10FCVal 0.217 0.219 -0.002 1.14e-01 0.199 0.199 0.000 9.41e-01
Breast_Cancer LDpred2.10FCVal lassosum.10FCVal 0.223 0.219 0.004 7.62e-03 0.211 0.199 0.012 2.39e-04
Breast_Cancer LDpred2.10FCVal LDpred1.MultiPRS 0.223 0.211 0.012 5.72e-02 0.211 0.195 0.017 1.03e-05
Breast_Cancer PRScs.PseudoVal LDpred1.MultiPRS 0.220 0.211 0.009 1.54e-01 0.208 0.195 0.013 5.03e-04
Breast_Cancer LDpred2.Inf LDpred1.MultiPRS 0.168 0.211 -0.043 4.60e-11 0.160 0.195 -0.034 4.42e-08
Breast_Cancer pT+clump.10FCVal LDpred1.MultiPRS 0.179 0.211 -0.032 9.31e-07 0.167 0.195 -0.027 5.69e-04
Breast_Cancer SBayesR.PseudoVal LDpred1.MultiPRS 0.221 0.211 0.010 1.36e-01 0.205 0.195 0.010 7.84e-02
Breast_Cancer All.MultiPRS LDpred1.MultiPRS 0.228 0.211 0.016 1.08e-15 0.215 0.195 0.021 7.66e-07
Breast_Cancer LDpred1.10FCVal LDpred1.MultiPRS 0.201 0.211 -0.010 1.11e-01 0.186 0.195 -0.009 2.74e-03
Breast_Cancer LDpred1.MultiPRS LDpred1.MultiPRS 0.211 0.211 0.000 1.00e+00 0.195 0.195 0.000 1.00e+00
Breast_Cancer PRScs.10FCVal LDpred1.MultiPRS 0.220 0.211 0.009 1.88e-01 0.207 0.195 0.013 1.30e-03
Breast_Cancer lassosum.PseudoVal LDpred1.MultiPRS 0.217 0.211 0.006 3.64e-01 0.199 0.195 0.005 4.05e-01
Breast_Cancer pT+clump.MultiPRS LDpred1.MultiPRS 0.200 0.211 -0.011 1.06e-01 0.188 0.195 -0.007 2.46e-01
Breast_Cancer LDpred1.Inf LDpred1.MultiPRS 0.172 0.211 -0.039 2.07e-09 0.162 0.195 -0.033 1.30e-08
Breast_Cancer lassosum.MultiPRS LDpred1.MultiPRS 0.225 0.211 0.014 3.87e-02 0.212 0.195 0.017 1.49e-04
Breast_Cancer PRScs.MultiPRS LDpred1.MultiPRS 0.222 0.211 0.011 1.12e-01 0.210 0.195 0.016 2.31e-05
Breast_Cancer lassosum.10FCVal LDpred1.MultiPRS 0.219 0.211 0.008 2.21e-01 0.199 0.195 0.004 3.53e-01
Breast_Cancer LDpred2.PseudoVal LDpred1.MultiPRS 0.169 0.211 -0.042 1.22e-10 0.161 0.195 -0.034 5.76e-08
Breast_Cancer DBSLMM.PseudoVal LDpred1.MultiPRS 0.217 0.211 0.006 3.30e-01 0.211 0.195 0.016 4.98e-04
Breast_Cancer LDpred2.MultiPRS LDpred1.MultiPRS 0.224 0.211 0.013 5.36e-02 0.211 0.195 0.016 1.43e-04
Breast_Cancer SBLUP.Inf LDpred1.MultiPRS 0.168 0.211 -0.043 4.15e-11 0.158 0.195 -0.036 6.15e-09
Breast_Cancer All.MultiPRS LDpred1.Inf 0.228 0.172 0.056 2.56e-17 0.215 0.162 0.053 3.87e-14
Breast_Cancer LDpred2.PseudoVal LDpred1.Inf 0.169 0.172 -0.003 1.11e-02 0.161 0.162 -0.001 6.44e-01
Breast_Cancer SBayesR.PseudoVal LDpred1.Inf 0.221 0.172 0.049 1.33e-28 0.205 0.162 0.043 1.16e-06
Breast_Cancer LDpred2.MultiPRS LDpred1.Inf 0.224 0.172 0.052 1.84e-14 0.211 0.162 0.049 3.19e-12
Breast_Cancer PRScs.PseudoVal LDpred1.Inf 0.220 0.172 0.049 5.39e-62 0.208 0.162 0.046 4.13e-15
Breast_Cancer LDpred1.Inf LDpred1.Inf 0.172 0.172 0.000 1.00e+00 0.162 0.162 0.000 1.00e+00
Breast_Cancer pT+clump.10FCVal LDpred1.Inf 0.179 0.172 0.007 1.61e-01 0.167 0.162 0.005 5.92e-01
Breast_Cancer PRScs.MultiPRS LDpred1.Inf 0.222 0.172 0.050 2.33e-13 0.210 0.162 0.049 1.62e-14
Breast_Cancer lassosum.PseudoVal LDpred1.Inf 0.217 0.172 0.045 8.22e-25 0.199 0.162 0.037 2.34e-05
Breast_Cancer pT+clump.MultiPRS LDpred1.Inf 0.200 0.172 0.028 3.78e-05 0.188 0.162 0.026 5.36e-04
Breast_Cancer LDpred1.MultiPRS LDpred1.Inf 0.211 0.172 0.039 2.07e-09 0.195 0.162 0.033 1.30e-08
Breast_Cancer PRScs.10FCVal LDpred1.Inf 0.220 0.172 0.048 1.15e-54 0.207 0.162 0.045 1.32e-13
Breast_Cancer LDpred2.Inf LDpred1.Inf 0.168 0.172 -0.004 1.01e-03 0.160 0.162 -0.002 4.89e-01
Breast_Cancer SBLUP.Inf LDpred1.Inf 0.168 0.172 -0.004 3.48e-04 0.158 0.162 -0.004 1.23e-01
Breast_Cancer DBSLMM.PseudoVal LDpred1.Inf 0.217 0.172 0.046 7.43e-56 0.211 0.162 0.049 4.73e-17
Breast_Cancer lassosum.MultiPRS LDpred1.Inf 0.225 0.172 0.053 5.98e-15 0.212 0.162 0.050 2.69e-12
Breast_Cancer LDpred1.10FCVal LDpred1.Inf 0.201 0.172 0.029 4.41e-59 0.186 0.162 0.024 1.58e-11
Breast_Cancer lassosum.10FCVal LDpred1.Inf 0.219 0.172 0.047 6.72e-37 0.199 0.162 0.037 6.56e-07
Breast_Cancer LDpred2.10FCVal LDpred1.Inf 0.223 0.172 0.052 6.15e-61 0.211 0.162 0.049 4.56e-15
Breast_Cancer LDpred1.Inf LDpred1.10FCVal 0.172 0.201 -0.029 4.41e-59 0.162 0.186 -0.024 1.58e-11
Breast_Cancer PRScs.MultiPRS LDpred1.10FCVal 0.222 0.201 0.021 1.89e-03 0.210 0.186 0.025 4.14e-08
Breast_Cancer LDpred1.10FCVal LDpred1.10FCVal 0.201 0.201 0.000 1.00e+00 0.186 0.186 0.000 1.00e+00
Breast_Cancer All.MultiPRS LDpred1.10FCVal 0.228 0.201 0.027 4.03e-05 0.215 0.186 0.029 1.35e-08
Breast_Cancer SBayesR.PseudoVal LDpred1.10FCVal 0.221 0.201 0.020 7.87e-09 0.205 0.186 0.019 6.82e-03
Breast_Cancer DBSLMM.PseudoVal LDpred1.10FCVal 0.217 0.201 0.017 6.72e-14 0.211 0.186 0.025 5.79e-08
Breast_Cancer pT+clump.MultiPRS LDpred1.10FCVal 0.200 0.201 -0.001 9.21e-01 0.188 0.186 0.002 7.90e-01
Breast_Cancer lassosum.MultiPRS LDpred1.10FCVal 0.225 0.201 0.024 3.39e-04 0.212 0.186 0.026 1.03e-06
Breast_Cancer PRScs.10FCVal LDpred1.10FCVal 0.220 0.201 0.019 3.74e-18 0.207 0.186 0.021 1.49e-06
Breast_Cancer lassosum.10FCVal LDpred1.10FCVal 0.219 0.201 0.018 5.81e-11 0.199 0.186 0.013 2.09e-02
Breast_Cancer SBLUP.Inf LDpred1.10FCVal 0.168 0.201 -0.033 1.39e-57 0.158 0.186 -0.028 3.98e-11
Breast_Cancer LDpred2.PseudoVal LDpred1.10FCVal 0.169 0.201 -0.032 1.66e-52 0.161 0.186 -0.025 2.63e-09
Breast_Cancer pT+clump.10FCVal LDpred1.10FCVal 0.179 0.201 -0.022 2.79e-07 0.167 0.186 -0.019 2.75e-02
Breast_Cancer LDpred2.MultiPRS LDpred1.10FCVal 0.224 0.201 0.023 5.72e-04 0.211 0.186 0.025 1.18e-06
Breast_Cancer PRScs.PseudoVal LDpred1.10FCVal 0.220 0.201 0.020 7.40e-22 0.208 0.186 0.022 1.50e-07
Breast_Cancer LDpred2.10FCVal LDpred1.10FCVal 0.223 0.201 0.023 1.00e-25 0.211 0.186 0.025 9.83e-09
Breast_Cancer LDpred1.MultiPRS LDpred1.10FCVal 0.211 0.201 0.010 1.11e-01 0.195 0.186 0.009 2.74e-03
Breast_Cancer LDpred2.Inf LDpred1.10FCVal 0.168 0.201 -0.033 1.52e-54 0.160 0.186 -0.026 1.66e-09
Breast_Cancer lassosum.PseudoVal LDpred1.10FCVal 0.217 0.201 0.016 1.79e-06 0.199 0.186 0.013 5.42e-02
Breast_Cancer LDpred1.Inf LDpred2.MultiPRS 0.172 0.224 -0.052 1.84e-14 0.162 0.211 -0.049 3.19e-12
Breast_Cancer DBSLMM.PseudoVal LDpred2.MultiPRS 0.217 0.224 -0.007 3.19e-01 0.211 0.211 0.000 9.77e-01
Breast_Cancer SBLUP.Inf LDpred2.MultiPRS 0.168 0.224 -0.057 1.44e-16 0.158 0.211 -0.052 5.15e-13
Breast_Cancer LDpred2.Inf LDpred2.MultiPRS 0.168 0.224 -0.056 1.59e-16 0.160 0.211 -0.051 1.28e-12
Breast_Cancer pT+clump.10FCVal LDpred2.MultiPRS 0.179 0.224 -0.046 2.54e-11 0.167 0.211 -0.044 2.71e-10
Breast_Cancer LDpred2.10FCVal LDpred2.MultiPRS 0.223 0.224 -0.001 9.09e-01 0.211 0.211 0.000 8.35e-01
Breast_Cancer PRScs.PseudoVal LDpred2.MultiPRS 0.220 0.224 -0.004 5.70e-01 0.208 0.211 -0.003 3.58e-01
Breast_Cancer LDpred1.10FCVal LDpred2.MultiPRS 0.201 0.224 -0.023 5.72e-04 0.186 0.211 -0.025 1.18e-06
Breast_Cancer All.MultiPRS LDpred2.MultiPRS 0.228 0.224 0.003 6.28e-01 0.215 0.211 0.004 5.16e-02
Breast_Cancer SBayesR.PseudoVal LDpred2.MultiPRS 0.221 0.224 -0.003 6.20e-01 0.205 0.211 -0.006 1.61e-01
Breast_Cancer lassosum.10FCVal LDpred2.MultiPRS 0.219 0.224 -0.005 4.48e-01 0.199 0.211 -0.012 1.56e-03
Breast_Cancer pT+clump.MultiPRS LDpred2.MultiPRS 0.200 0.224 -0.024 4.03e-04 0.188 0.211 -0.023 2.14e-05
Breast_Cancer lassosum.MultiPRS LDpred2.MultiPRS 0.225 0.224 0.001 5.62e-01 0.212 0.211 0.001 6.85e-01
Breast_Cancer PRScs.10FCVal LDpred2.MultiPRS 0.220 0.224 -0.005 5.03e-01 0.207 0.211 -0.003 2.72e-01
Breast_Cancer PRScs.MultiPRS LDpred2.MultiPRS 0.222 0.224 -0.002 7.41e-01 0.210 0.211 0.000 9.62e-01
Breast_Cancer lassosum.PseudoVal LDpred2.MultiPRS 0.217 0.224 -0.007 2.90e-01 0.199 0.211 -0.011 4.64e-03
Breast_Cancer LDpred2.PseudoVal LDpred2.MultiPRS 0.169 0.224 -0.056 5.16e-16 0.161 0.211 -0.050 1.46e-12
Breast_Cancer LDpred1.MultiPRS LDpred2.MultiPRS 0.211 0.224 -0.013 5.36e-02 0.195 0.211 -0.016 1.43e-04
Breast_Cancer LDpred2.MultiPRS LDpred2.MultiPRS 0.224 0.224 0.000 1.00e+00 0.211 0.211 0.000 1.00e+00
Breast_Cancer LDpred1.Inf LDpred2.10FCVal 0.172 0.223 -0.052 6.15e-61 0.162 0.211 -0.049 4.56e-15
Breast_Cancer PRScs.MultiPRS LDpred2.10FCVal 0.222 0.223 -0.001 8.29e-01 0.210 0.211 -0.001 8.37e-01
Breast_Cancer LDpred2.MultiPRS LDpred2.10FCVal 0.224 0.223 0.001 9.09e-01 0.211 0.211 0.000 8.35e-01
Breast_Cancer PRScs.PseudoVal LDpred2.10FCVal 0.220 0.223 -0.003 2.71e-02 0.208 0.211 -0.003 2.28e-01
Breast_Cancer LDpred2.10FCVal LDpred2.10FCVal 0.223 0.223 0.000 1.00e+00 0.211 0.211 0.000 1.00e+00
Breast_Cancer lassosum.MultiPRS LDpred2.10FCVal 0.225 0.223 0.002 8.02e-01 0.212 0.211 0.001 7.83e-01
Breast_Cancer LDpred1.10FCVal LDpred2.10FCVal 0.201 0.223 -0.023 1.00e-25 0.186 0.211 -0.025 9.83e-09
Breast_Cancer All.MultiPRS LDpred2.10FCVal 0.228 0.223 0.004 5.31e-01 0.215 0.211 0.004 1.28e-01
Breast_Cancer SBayesR.PseudoVal LDpred2.10FCVal 0.221 0.223 -0.003 2.44e-01 0.205 0.211 -0.006 1.76e-01
Breast_Cancer DBSLMM.PseudoVal LDpred2.10FCVal 0.217 0.223 -0.006 2.79e-03 0.211 0.211 0.000 9.43e-01
Breast_Cancer pT+clump.MultiPRS LDpred2.10FCVal 0.200 0.223 -0.023 6.08e-04 0.188 0.211 -0.023 6.41e-06
Breast_Cancer lassosum.PseudoVal LDpred2.10FCVal 0.217 0.223 -0.006 2.21e-03 0.199 0.211 -0.012 4.64e-03
Breast_Cancer PRScs.10FCVal LDpred2.10FCVal 0.220 0.223 -0.004 8.00e-03 0.207 0.211 -0.004 1.69e-01
Breast_Cancer lassosum.10FCVal LDpred2.10FCVal 0.219 0.223 -0.004 7.62e-03 0.199 0.211 -0.012 2.39e-04
Breast_Cancer SBLUP.Inf LDpred2.10FCVal 0.168 0.223 -0.056 2.84e-66 0.158 0.211 -0.053 7.01e-16
Breast_Cancer LDpred2.PseudoVal LDpred2.10FCVal 0.169 0.223 -0.055 5.75e-68 0.161 0.211 -0.050 1.61e-15
Breast_Cancer pT+clump.10FCVal LDpred2.10FCVal 0.179 0.223 -0.045 9.93e-37 0.167 0.211 -0.044 4.14e-10
Breast_Cancer LDpred2.Inf LDpred2.10FCVal 0.168 0.223 -0.056 7.21e-69 0.160 0.211 -0.051 1.57e-15
Breast_Cancer LDpred1.MultiPRS LDpred2.10FCVal 0.211 0.223 -0.012 5.72e-02 0.195 0.211 -0.017 1.03e-05
Breast_Cancer lassosum.10FCVal LDpred2.PseudoVal 0.219 0.169 0.050 4.09e-40 0.199 0.161 0.038 5.08e-07
Breast_Cancer SBLUP.Inf LDpred2.PseudoVal 0.168 0.169 -0.001 1.60e-01 0.158 0.161 -0.002 1.04e-01
Breast_Cancer SBayesR.PseudoVal LDpred2.PseudoVal 0.221 0.169 0.052 1.73e-31 0.205 0.161 0.044 7.91e-07
Breast_Cancer All.MultiPRS LDpred2.PseudoVal 0.228 0.169 0.059 5.12e-19 0.215 0.161 0.054 3.92e-14
Breast_Cancer PRScs.PseudoVal LDpred2.PseudoVal 0.220 0.169 0.052 2.09e-66 0.208 0.161 0.047 5.51e-15
Breast_Cancer lassosum.MultiPRS LDpred2.PseudoVal 0.225 0.169 0.056 1.58e-16 0.212 0.161 0.051 2.04e-12
Breast_Cancer PRScs.MultiPRS LDpred2.PseudoVal 0.222 0.169 0.053 8.17e-15 0.210 0.161 0.050 2.45e-14
Breast_Cancer LDpred2.MultiPRS LDpred2.PseudoVal 0.224 0.169 0.056 5.16e-16 0.211 0.161 0.050 1.46e-12
Breast_Cancer PRScs.10FCVal LDpred2.PseudoVal 0.220 0.169 0.051 2.76e-59 0.207 0.161 0.046 1.15e-13
Breast_Cancer LDpred2.PseudoVal LDpred2.PseudoVal 0.169 0.169 0.000 1.00e+00 0.161 0.161 0.000 1.00e+00
Breast_Cancer pT+clump.MultiPRS LDpred2.PseudoVal 0.200 0.169 0.031 5.11e-06 0.188 0.161 0.027 5.11e-04
Breast_Cancer pT+clump.10FCVal LDpred2.PseudoVal 0.179 0.169 0.010 4.74e-02 0.167 0.161 0.006 5.26e-01
Breast_Cancer lassosum.PseudoVal LDpred2.PseudoVal 0.217 0.169 0.048 4.77e-27 0.199 0.161 0.039 2.02e-05
Breast_Cancer LDpred1.Inf LDpred2.PseudoVal 0.172 0.169 0.003 1.11e-02 0.162 0.161 0.001 6.44e-01
Breast_Cancer LDpred1.MultiPRS LDpred2.PseudoVal 0.211 0.169 0.042 1.22e-10 0.195 0.161 0.034 5.76e-08
Breast_Cancer LDpred1.10FCVal LDpred2.PseudoVal 0.201 0.169 0.032 1.66e-52 0.186 0.161 0.025 2.63e-09
Breast_Cancer LDpred2.Inf LDpred2.PseudoVal 0.168 0.169 -0.001 2.98e-05 0.160 0.161 -0.001 2.09e-01
Breast_Cancer LDpred2.10FCVal LDpred2.PseudoVal 0.223 0.169 0.055 5.75e-68 0.211 0.161 0.050 1.61e-15
Breast_Cancer DBSLMM.PseudoVal LDpred2.PseudoVal 0.217 0.169 0.049 7.14e-62 0.211 0.161 0.050 2.83e-17
Breast_Cancer pT+clump.MultiPRS LDpred2.Inf 0.200 0.168 0.032 2.58e-06 0.188 0.160 0.028 4.44e-04
Breast_Cancer lassosum.MultiPRS LDpred2.Inf 0.225 0.168 0.057 4.78e-17 0.212 0.160 0.052 1.88e-12
Breast_Cancer SBayesR.PseudoVal LDpred2.Inf 0.221 0.168 0.053 5.70e-32 0.205 0.160 0.045 7.43e-07
Breast_Cancer All.MultiPRS LDpred2.Inf 0.228 0.168 0.060 1.35e-19 0.215 0.160 0.055 3.36e-14
Breast_Cancer SBLUP.Inf LDpred2.Inf 0.168 0.168 0.000 9.24e-01 0.158 0.160 -0.002 2.14e-01
Breast_Cancer LDpred2.PseudoVal LDpred2.Inf 0.169 0.168 0.001 2.98e-05 0.161 0.160 0.001 2.09e-01
Breast_Cancer PRScs.MultiPRS LDpred2.Inf 0.222 0.168 0.054 2.65e-15 0.210 0.160 0.050 3.38e-14
Breast_Cancer LDpred2.MultiPRS LDpred2.Inf 0.224 0.168 0.056 1.59e-16 0.211 0.160 0.051 1.28e-12
Breast_Cancer PRScs.10FCVal LDpred2.Inf 0.220 0.168 0.052 3.12e-59 0.207 0.160 0.047 1.76e-13
Breast_Cancer LDpred1.Inf LDpred2.Inf 0.172 0.168 0.004 1.01e-03 0.162 0.160 0.002 4.89e-01
Breast_Cancer LDpred1.MultiPRS LDpred2.Inf 0.211 0.168 0.043 4.60e-11 0.195 0.160 0.034 4.42e-08
Breast_Cancer pT+clump.10FCVal LDpred2.Inf 0.179 0.168 0.011 3.12e-02 0.167 0.160 0.007 4.94e-01
Breast_Cancer lassosum.PseudoVal LDpred2.Inf 0.217 0.168 0.049 1.60e-27 0.199 0.160 0.039 1.85e-05
Breast_Cancer PRScs.PseudoVal LDpred2.Inf 0.220 0.168 0.053 2.64e-66 0.208 0.160 0.048 8.61e-15
Breast_Cancer DBSLMM.PseudoVal LDpred2.Inf 0.217 0.168 0.050 4.35e-63 0.211 0.160 0.051 2.59e-17
Breast_Cancer LDpred1.10FCVal LDpred2.Inf 0.201 0.168 0.033 1.52e-54 0.186 0.160 0.026 1.66e-09
Breast_Cancer LDpred2.Inf LDpred2.Inf 0.168 0.168 0.000 1.00e+00 0.160 0.160 0.000 1.00e+00
Breast_Cancer lassosum.10FCVal LDpred2.Inf 0.219 0.168 0.051 1.14e-40 0.199 0.160 0.039 4.70e-07
Breast_Cancer LDpred2.10FCVal LDpred2.Inf 0.223 0.168 0.056 7.21e-69 0.211 0.160 0.051 1.57e-15
Breast_Cancer PRScs.10FCVal PRScs.MultiPRS 0.220 0.222 -0.002 7.35e-01 0.207 0.210 -0.003 2.17e-02
Breast_Cancer LDpred1.10FCVal PRScs.MultiPRS 0.201 0.222 -0.021 1.89e-03 0.186 0.210 -0.025 4.14e-08
Breast_Cancer lassosum.MultiPRS PRScs.MultiPRS 0.225 0.222 0.003 6.40e-01 0.212 0.210 0.001 6.00e-01
Breast_Cancer LDpred2.MultiPRS PRScs.MultiPRS 0.224 0.222 0.002 7.41e-01 0.211 0.210 0.000 9.62e-01
Breast_Cancer All.MultiPRS PRScs.MultiPRS 0.228 0.222 0.006 4.18e-01 0.215 0.210 0.005 1.02e-01
Breast_Cancer PRScs.PseudoVal PRScs.MultiPRS 0.220 0.222 -0.002 8.13e-01 0.208 0.210 -0.003 3.31e-02
Breast_Cancer LDpred1.MultiPRS PRScs.MultiPRS 0.211 0.222 -0.011 1.12e-01 0.195 0.210 -0.016 2.31e-05
Breast_Cancer pT+clump.MultiPRS PRScs.MultiPRS 0.200 0.222 -0.022 1.34e-03 0.188 0.210 -0.023 1.31e-06
Breast_Cancer lassosum.PseudoVal PRScs.MultiPRS 0.217 0.222 -0.005 4.69e-01 0.199 0.210 -0.011 3.74e-03
Breast_Cancer SBayesR.PseudoVal PRScs.MultiPRS 0.221 0.222 -0.001 8.69e-01 0.205 0.210 -0.006 1.68e-01
Breast_Cancer DBSLMM.PseudoVal PRScs.MultiPRS 0.217 0.222 -0.005 5.06e-01 0.211 0.210 0.000 9.39e-01
Breast_Cancer SBLUP.Inf PRScs.MultiPRS 0.168 0.222 -0.054 2.49e-15 0.158 0.210 -0.052 3.63e-15
Breast_Cancer LDpred2.Inf PRScs.MultiPRS 0.168 0.222 -0.054 2.65e-15 0.160 0.210 -0.050 3.38e-14
Breast_Cancer pT+clump.10FCVal PRScs.MultiPRS 0.179 0.222 -0.043 2.60e-10 0.167 0.210 -0.043 6.33e-11
Breast_Cancer LDpred2.10FCVal PRScs.MultiPRS 0.223 0.222 0.001 8.29e-01 0.211 0.210 0.001 8.37e-01
Breast_Cancer lassosum.10FCVal PRScs.MultiPRS 0.219 0.222 -0.003 6.71e-01 0.199 0.210 -0.011 9.27e-04
Breast_Cancer LDpred2.PseudoVal PRScs.MultiPRS 0.169 0.222 -0.053 8.17e-15 0.161 0.210 -0.050 2.45e-14
Breast_Cancer LDpred1.Inf PRScs.MultiPRS 0.172 0.222 -0.050 2.33e-13 0.162 0.210 -0.049 1.62e-14
Breast_Cancer PRScs.MultiPRS PRScs.MultiPRS 0.222 0.222 0.000 1.00e+00 0.210 0.210 0.000 1.00e+00
Breast_Cancer LDpred2.PseudoVal PRScs.10FCVal 0.169 0.220 -0.051 2.76e-59 0.161 0.207 -0.046 1.15e-13
Breast_Cancer PRScs.10FCVal PRScs.10FCVal 0.220 0.220 0.000 1.00e+00 0.207 0.207 0.000 1.00e+00
Breast_Cancer LDpred2.MultiPRS PRScs.10FCVal 0.224 0.220 0.005 5.03e-01 0.211 0.207 0.003 2.72e-01
Breast_Cancer pT+clump.MultiPRS PRScs.10FCVal 0.200 0.220 -0.020 4.11e-03 0.188 0.207 -0.020 7.77e-05
Breast_Cancer LDpred1.Inf PRScs.10FCVal 0.172 0.220 -0.048 1.15e-54 0.162 0.207 -0.045 1.32e-13
Breast_Cancer LDpred1.MultiPRS PRScs.10FCVal 0.211 0.220 -0.009 1.88e-01 0.195 0.207 -0.013 1.30e-03
Breast_Cancer pT+clump.10FCVal PRScs.10FCVal 0.179 0.220 -0.041 8.48e-33 0.167 0.207 -0.040 4.65e-09
Breast_Cancer lassosum.PseudoVal PRScs.10FCVal 0.217 0.220 -0.003 2.11e-01 0.199 0.207 -0.008 6.16e-02
Breast_Cancer PRScs.PseudoVal PRScs.10FCVal 0.220 0.220 0.001 4.96e-01 0.208 0.207 0.001 7.91e-01
Breast_Cancer DBSLMM.PseudoVal PRScs.10FCVal 0.217 0.220 -0.002 2.02e-01 0.211 0.207 0.004 2.99e-01
Breast_Cancer SBLUP.Inf PRScs.10FCVal 0.168 0.220 -0.052 1.05e-59 0.158 0.207 -0.049 1.77e-14
Breast_Cancer LDpred2.Inf PRScs.10FCVal 0.168 0.220 -0.052 3.12e-59 0.160 0.207 -0.047 1.76e-13
Breast_Cancer lassosum.10FCVal PRScs.10FCVal 0.219 0.220 -0.001 7.42e-01 0.199 0.207 -0.008 2.54e-02
Breast_Cancer LDpred2.10FCVal PRScs.10FCVal 0.223 0.220 0.004 8.00e-03 0.211 0.207 0.004 1.69e-01
Breast_Cancer lassosum.MultiPRS PRScs.10FCVal 0.225 0.220 0.005 4.20e-01 0.212 0.207 0.005 1.14e-01
Breast_Cancer LDpred1.10FCVal PRScs.10FCVal 0.201 0.220 -0.019 3.74e-18 0.186 0.207 -0.021 1.49e-06
Breast_Cancer All.MultiPRS PRScs.10FCVal 0.228 0.220 0.008 2.27e-01 0.215 0.207 0.008 1.16e-02
Breast_Cancer SBayesR.PseudoVal PRScs.10FCVal 0.221 0.220 0.001 5.86e-01 0.205 0.207 -0.002 6.20e-01
Breast_Cancer PRScs.MultiPRS PRScs.10FCVal 0.222 0.220 0.002 7.35e-01 0.210 0.207 0.003 2.17e-02
Breast_Cancer All.MultiPRS PRScs.PseudoVal 0.228 0.220 0.007 2.70e-01 0.215 0.208 0.007 1.82e-02
Breast_Cancer pT+clump.MultiPRS PRScs.PseudoVal 0.200 0.220 -0.020 2.96e-03 0.188 0.208 -0.020 4.61e-05
Breast_Cancer LDpred2.PseudoVal PRScs.PseudoVal 0.169 0.220 -0.052 2.09e-66 0.161 0.208 -0.047 5.51e-15
Breast_Cancer SBayesR.PseudoVal PRScs.PseudoVal 0.221 0.220 0.000 8.32e-01 0.205 0.208 -0.003 5.56e-01
Breast_Cancer LDpred2.MultiPRS PRScs.PseudoVal 0.224 0.220 0.004 5.70e-01 0.211 0.208 0.003 3.58e-01
Breast_Cancer SBLUP.Inf PRScs.PseudoVal 0.168 0.220 -0.053 5.03e-67 0.158 0.208 -0.049 6.60e-16
Breast_Cancer LDpred1.Inf PRScs.PseudoVal 0.172 0.220 -0.049 5.39e-62 0.162 0.208 -0.046 4.13e-15
Breast_Cancer PRScs.10FCVal PRScs.PseudoVal 0.220 0.220 -0.001 4.96e-01 0.207 0.208 -0.001 7.91e-01
Breast_Cancer LDpred2.Inf PRScs.PseudoVal 0.168 0.220 -0.053 2.64e-66 0.160 0.208 -0.048 8.61e-15
Breast_Cancer PRScs.PseudoVal PRScs.PseudoVal 0.220 0.220 0.000 1.00e+00 0.208 0.208 0.000 1.00e+00
Breast_Cancer LDpred2.10FCVal PRScs.PseudoVal 0.223 0.220 0.003 2.71e-02 0.211 0.208 0.003 2.28e-01
Breast_Cancer pT+clump.10FCVal PRScs.PseudoVal 0.179 0.220 -0.042 6.22e-33 0.167 0.208 -0.041 4.21e-09
Breast_Cancer PRScs.MultiPRS PRScs.PseudoVal 0.222 0.220 0.002 8.13e-01 0.210 0.208 0.003 3.31e-02
Breast_Cancer lassosum.PseudoVal PRScs.PseudoVal 0.217 0.220 -0.003 1.32e-01 0.199 0.208 -0.008 5.69e-02
Breast_Cancer lassosum.10FCVal PRScs.PseudoVal 0.219 0.220 -0.001 4.82e-01 0.199 0.208 -0.009 1.94e-02
Breast_Cancer LDpred1.MultiPRS PRScs.PseudoVal 0.211 0.220 -0.009 1.54e-01 0.195 0.208 -0.013 5.03e-04
Breast_Cancer lassosum.MultiPRS PRScs.PseudoVal 0.225 0.220 0.005 4.81e-01 0.212 0.208 0.004 1.76e-01
Breast_Cancer LDpred1.10FCVal PRScs.PseudoVal 0.201 0.220 -0.020 7.40e-22 0.186 0.208 -0.022 1.50e-07
Breast_Cancer DBSLMM.PseudoVal PRScs.PseudoVal 0.217 0.220 -0.003 8.35e-02 0.211 0.208 0.003 3.66e-01
Breast_Cancer All.MultiPRS pT+clump.MultiPRS 0.228 0.200 0.027 5.53e-05 0.215 0.188 0.027 6.94e-08
Breast_Cancer SBayesR.PseudoVal pT+clump.MultiPRS 0.221 0.200 0.021 2.34e-03 0.205 0.188 0.017 1.95e-03
Breast_Cancer LDpred1.MultiPRS pT+clump.MultiPRS 0.211 0.200 0.011 1.06e-01 0.195 0.188 0.007 2.46e-01
Breast_Cancer pT+clump.MultiPRS pT+clump.MultiPRS 0.200 0.200 0.000 1.00e+00 0.188 0.188 0.000 1.00e+00
Breast_Cancer lassosum.PseudoVal pT+clump.MultiPRS 0.217 0.200 0.017 1.31e-02 0.199 0.188 0.012 3.21e-02
Breast_Cancer PRScs.10FCVal pT+clump.MultiPRS 0.220 0.200 0.020 4.11e-03 0.207 0.188 0.020 7.77e-05
Breast_Cancer DBSLMM.PseudoVal pT+clump.MultiPRS 0.217 0.200 0.017 1.10e-02 0.211 0.188 0.023 3.20e-06
Breast_Cancer SBLUP.Inf pT+clump.MultiPRS 0.168 0.200 -0.032 2.47e-06 0.158 0.188 -0.029 1.42e-04
Breast_Cancer LDpred2.Inf pT+clump.MultiPRS 0.168 0.200 -0.032 2.58e-06 0.160 0.188 -0.028 4.44e-04
Breast_Cancer pT+clump.10FCVal pT+clump.MultiPRS 0.179 0.200 -0.021 1.89e-03 0.167 0.188 -0.021 1.49e-05
Breast_Cancer LDpred2.10FCVal pT+clump.MultiPRS 0.223 0.200 0.023 6.08e-04 0.211 0.188 0.023 6.41e-06
Breast_Cancer PRScs.PseudoVal pT+clump.MultiPRS 0.220 0.200 0.020 2.96e-03 0.208 0.188 0.020 4.61e-05
Breast_Cancer LDpred1.10FCVal pT+clump.MultiPRS 0.201 0.200 0.001 9.21e-01 0.186 0.188 -0.002 7.90e-01
Breast_Cancer LDpred1.Inf pT+clump.MultiPRS 0.172 0.200 -0.028 3.78e-05 0.162 0.188 -0.026 5.36e-04
Breast_Cancer PRScs.MultiPRS pT+clump.MultiPRS 0.222 0.200 0.022 1.34e-03 0.210 0.188 0.023 1.31e-06
Breast_Cancer lassosum.10FCVal pT+clump.MultiPRS 0.219 0.200 0.019 5.40e-03 0.199 0.188 0.011 2.53e-02
Breast_Cancer LDpred2.PseudoVal pT+clump.MultiPRS 0.169 0.200 -0.031 5.11e-06 0.161 0.188 -0.027 5.11e-04
Breast_Cancer lassosum.MultiPRS pT+clump.MultiPRS 0.225 0.200 0.025 2.44e-04 0.212 0.188 0.024 7.15e-07
Breast_Cancer LDpred2.MultiPRS pT+clump.MultiPRS 0.224 0.200 0.024 4.03e-04 0.211 0.188 0.023 2.14e-05
Breast_Cancer LDpred2.10FCVal pT+clump.10FCVal 0.223 0.179 0.045 9.93e-37 0.211 0.167 0.044 4.14e-10
Breast_Cancer pT+clump.MultiPRS pT+clump.10FCVal 0.200 0.179 0.021 1.89e-03 0.188 0.167 0.021 1.49e-05
Breast_Cancer LDpred2.Inf pT+clump.10FCVal 0.168 0.179 -0.011 3.12e-02 0.160 0.167 -0.007 4.94e-01
Breast_Cancer SBayesR.PseudoVal pT+clump.10FCVal 0.221 0.179 0.042 6.15e-41 0.205 0.167 0.038 1.01e-09
Breast_Cancer PRScs.MultiPRS pT+clump.10FCVal 0.222 0.179 0.043 2.60e-10 0.210 0.167 0.043 6.33e-11
Breast_Cancer SBLUP.Inf pT+clump.10FCVal 0.168 0.179 -0.011 2.98e-02 0.158 0.167 -0.009 3.86e-01
Breast_Cancer lassosum.MultiPRS pT+clump.10FCVal 0.225 0.179 0.047 9.73e-12 0.212 0.167 0.045 3.14e-12
Breast_Cancer PRScs.10FCVal pT+clump.10FCVal 0.220 0.179 0.041 8.48e-33 0.207 0.167 0.040 4.65e-09
Breast_Cancer LDpred2.MultiPRS pT+clump.10FCVal 0.224 0.179 0.046 2.54e-11 0.211 0.167 0.044 2.71e-10
Breast_Cancer lassosum.10FCVal pT+clump.10FCVal 0.219 0.179 0.040 3.58e-34 0.199 0.167 0.032 1.31e-06
Breast_Cancer LDpred2.PseudoVal pT+clump.10FCVal 0.169 0.179 -0.010 4.74e-02 0.161 0.167 -0.006 5.26e-01
Breast_Cancer LDpred1.MultiPRS pT+clump.10FCVal 0.211 0.179 0.032 9.31e-07 0.195 0.167 0.027 5.69e-04
Breast_Cancer pT+clump.10FCVal pT+clump.10FCVal 0.179 0.179 0.000 1.00e+00 0.167 0.167 0.000 1.00e+00
Breast_Cancer All.MultiPRS pT+clump.10FCVal 0.228 0.179 0.049 1.19e-13 0.215 0.167 0.048 4.23e-13
Breast_Cancer LDpred1.Inf pT+clump.10FCVal 0.172 0.179 -0.007 1.61e-01 0.162 0.167 -0.005 5.92e-01
Breast_Cancer DBSLMM.PseudoVal pT+clump.10FCVal 0.217 0.179 0.039 1.13e-26 0.211 0.167 0.044 1.63e-09
Breast_Cancer LDpred1.10FCVal pT+clump.10FCVal 0.201 0.179 0.022 2.79e-07 0.186 0.167 0.019 2.75e-02
Breast_Cancer lassosum.PseudoVal pT+clump.10FCVal 0.217 0.179 0.038 5.41e-37 0.199 0.167 0.032 7.03e-08
Breast_Cancer PRScs.PseudoVal pT+clump.10FCVal 0.220 0.179 0.042 6.22e-33 0.208 0.167 0.041 4.21e-09
Breast_Cancer pT+clump.MultiPRS SBayesR.PseudoVal 0.200 0.221 -0.021 2.34e-03 0.188 0.205 -0.017 1.95e-03
Breast_Cancer LDpred1.10FCVal SBayesR.PseudoVal 0.201 0.221 -0.020 7.87e-09 0.186 0.205 -0.019 6.82e-03
Breast_Cancer PRScs.10FCVal SBayesR.PseudoVal 0.220 0.221 -0.001 5.86e-01 0.207 0.205 0.002 6.20e-01
Breast_Cancer LDpred2.10FCVal SBayesR.PseudoVal 0.223 0.221 0.003 2.44e-01 0.211 0.205 0.006 1.76e-01
Breast_Cancer lassosum.10FCVal SBayesR.PseudoVal 0.219 0.221 -0.002 4.32e-01 0.199 0.205 -0.006 1.88e-01
Breast_Cancer LDpred2.PseudoVal SBayesR.PseudoVal 0.169 0.221 -0.052 1.73e-31 0.161 0.205 -0.044 7.91e-07
Breast_Cancer lassosum.MultiPRS SBayesR.PseudoVal 0.225 0.221 0.004 5.27e-01 0.212 0.205 0.007 6.17e-02
Breast_Cancer LDpred2.MultiPRS SBayesR.PseudoVal 0.224 0.221 0.003 6.20e-01 0.211 0.205 0.006 1.61e-01
Breast_Cancer All.MultiPRS SBayesR.PseudoVal 0.228 0.221 0.007 3.04e-01 0.215 0.205 0.010 2.21e-03
Breast_Cancer PRScs.PseudoVal SBayesR.PseudoVal 0.220 0.221 0.000 8.32e-01 0.208 0.205 0.003 5.56e-01
Breast_Cancer LDpred1.MultiPRS SBayesR.PseudoVal 0.211 0.221 -0.010 1.36e-01 0.195 0.205 -0.010 7.84e-02
Breast_Cancer pT+clump.10FCVal SBayesR.PseudoVal 0.179 0.221 -0.042 6.15e-41 0.167 0.205 -0.038 1.01e-09
Breast_Cancer lassosum.PseudoVal SBayesR.PseudoVal 0.217 0.221 -0.004 3.57e-02 0.199 0.205 -0.006 1.10e-01
Breast_Cancer SBayesR.PseudoVal SBayesR.PseudoVal 0.221 0.221 0.000 1.00e+00 0.205 0.205 0.000 1.00e+00
Breast_Cancer DBSLMM.PseudoVal SBayesR.PseudoVal 0.217 0.221 -0.003 1.87e-01 0.211 0.205 0.006 2.63e-01
Breast_Cancer SBLUP.Inf SBayesR.PseudoVal 0.168 0.221 -0.053 8.23e-32 0.158 0.205 -0.047 2.98e-07
Breast_Cancer LDpred2.Inf SBayesR.PseudoVal 0.168 0.221 -0.053 5.70e-32 0.160 0.205 -0.045 7.43e-07
Breast_Cancer LDpred1.Inf SBayesR.PseudoVal 0.172 0.221 -0.049 1.33e-28 0.162 0.205 -0.043 1.16e-06
Breast_Cancer PRScs.MultiPRS SBayesR.PseudoVal 0.222 0.221 0.001 8.69e-01 0.210 0.205 0.006 1.68e-01
Breast_Cancer LDpred2.10FCVal SBLUP.Inf 0.223 0.168 0.056 2.84e-66 0.211 0.158 0.053 7.01e-16
Breast_Cancer PRScs.PseudoVal SBLUP.Inf 0.220 0.168 0.053 5.03e-67 0.208 0.158 0.049 6.60e-16
Breast_Cancer LDpred1.10FCVal SBLUP.Inf 0.201 0.168 0.033 1.39e-57 0.186 0.158 0.028 3.98e-11
Breast_Cancer LDpred2.Inf SBLUP.Inf 0.168 0.168 0.000 9.24e-01 0.160 0.158 0.002 2.14e-01
Breast_Cancer SBayesR.PseudoVal SBLUP.Inf 0.221 0.168 0.053 8.23e-32 0.205 0.158 0.047 2.98e-07
Breast_Cancer lassosum.10FCVal SBLUP.Inf 0.219 0.168 0.051 5.81e-41 0.199 0.158 0.041 1.27e-07
Breast_Cancer pT+clump.MultiPRS SBLUP.Inf 0.200 0.168 0.032 2.47e-06 0.188 0.158 0.029 1.42e-04
Breast_Cancer lassosum.MultiPRS SBLUP.Inf 0.225 0.168 0.057 4.39e-17 0.212 0.158 0.054 2.59e-13
Breast_Cancer PRScs.10FCVal SBLUP.Inf 0.220 0.168 0.052 1.05e-59 0.207 0.158 0.049 1.77e-14
Breast_Cancer PRScs.MultiPRS SBLUP.Inf 0.222 0.168 0.054 2.49e-15 0.210 0.158 0.052 3.63e-15
Breast_Cancer LDpred1.MultiPRS SBLUP.Inf 0.211 0.168 0.043 4.15e-11 0.195 0.158 0.036 6.15e-09
Breast_Cancer LDpred2.PseudoVal SBLUP.Inf 0.169 0.168 0.001 1.60e-01 0.161 0.158 0.002 1.04e-01
Breast_Cancer LDpred1.Inf SBLUP.Inf 0.172 0.168 0.004 3.48e-04 0.162 0.158 0.004 1.23e-01
Breast_Cancer LDpred2.MultiPRS SBLUP.Inf 0.224 0.168 0.057 1.44e-16 0.211 0.158 0.052 5.15e-13
Breast_Cancer All.MultiPRS SBLUP.Inf 0.228 0.168 0.060 1.18e-19 0.215 0.158 0.057 6.47e-15
Breast_Cancer SBLUP.Inf SBLUP.Inf 0.168 0.168 0.000 1.00e+00 0.158 0.158 0.000 1.00e+00
Breast_Cancer DBSLMM.PseudoVal SBLUP.Inf 0.217 0.168 0.050 7.26e-65 0.211 0.158 0.052 6.94e-19
Breast_Cancer pT+clump.10FCVal SBLUP.Inf 0.179 0.168 0.011 2.98e-02 0.167 0.158 0.009 3.86e-01
Breast_Cancer lassosum.PseudoVal SBLUP.Inf 0.217 0.168 0.049 1.43e-27 0.199 0.158 0.041 7.57e-06

Show cross-validation differences between methods

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation differences between methods

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation


4.1.2 TEDS

Show pT+clump method results

Correlation between PRS model predictions and observed values in TEDS
Phenotype Method Model CrossVal R (SE) IndepVal R (SE)
Height21 pT+clump (sparse) 10FCVal 0.387 (0.014) 0.353 (0.028)
Height21 pT+clump (sparse) Multi-PRS 0.4 (0.014) 0.388 (0.028)
Height21 pT+clump (non-nested) 10FCVal 0.326 (0.014) 0.305 (0.029)
Height21 pT+clump (non-nested) Multi-PRS 0.398 (0.014) 0.386 (0.028)
Height21 pT+clump (dense) 10FCVal 0.396 (0.014) 0.366 (0.028)
Height21 pT+clump (dense) Multi-PRS 0.405 (0.014) 0.391 (0.028)
BMI21 pT+clump (sparse) 10FCVal 0.31 (0.015) 0.301 (0.03)
BMI21 pT+clump (sparse) Multi-PRS 0.317 (0.015) 0.295 (0.03)
BMI21 pT+clump (non-nested) 10FCVal 0.214 (0.015) 0.179 (0.03)
BMI21 pT+clump (non-nested) Multi-PRS 0.313 (0.015) 0.291 (0.03)
BMI21 pT+clump (dense) 10FCVal 0.31 (0.015) 0.302 (0.03)
BMI21 pT+clump (dense) Multi-PRS 0.317 (0.015) 0.295 (0.03)
GCSE pT+clump (sparse) 10FCVal 0.373 (0.012) 0.311 (0.025)
GCSE pT+clump (sparse) Multi-PRS 0.381 (0.012) 0.328 (0.025)
GCSE pT+clump (non-nested) 10FCVal 0.256 (0.013) 0.232 (0.025)
GCSE pT+clump (non-nested) Multi-PRS 0.381 (0.012) 0.328 (0.025)
GCSE pT+clump (dense) 10FCVal 0.373 (0.012) 0.315 (0.025)
GCSE pT+clump (dense) Multi-PRS 0.38 (0.012) 0.331 (0.025)
ADHD pT+clump (sparse) 10FCVal 0.094 (0.013) 0.15 (0.025)
ADHD pT+clump (sparse) Multi-PRS 0.095 (0.013) 0.162 (0.025)
ADHD pT+clump (non-nested) 10FCVal 0.064 (0.013) 0.105 (0.025)
ADHD pT+clump (non-nested) Multi-PRS 0.09 (0.013) 0.155 (0.025)
ADHD pT+clump (dense) 10FCVal 0.095 (0.013) 0.148 (0.025)
ADHD pT+clump (dense) Multi-PRS 0.108 (0.018) 0.155 (0.025)

Show cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show TEDS results table

Correlation between PRS model predictions and observed values in TEDS
Phenotype Method Model CrossVal_R CrossVal_R_SE CrossVal_pval IndepVal_R IndepVal_R_SE IndepVal_pval
Height21 All MultiPRS 0.447 0.014 4.31e-213 0.443 0.027 1.26e-53
Height21 DBSLMM PseudoVal 0.417 0.014 6.59e-183 0.428 0.027 6.01e-50
Height21 lassosum MultiPRS 0.440 0.014 7.96e-206 0.431 0.027 1.88e-50
Height21 lassosum 10FCVal 0.435 0.014 6.67e-201 0.425 0.027 4.36e-49
Height21 lassosum PseudoVal 0.357 0.014 1.64e-131 0.354 0.028 1.63e-33
Height21 LDpred1 MultiPRS 0.384 0.014 2.94e-153 0.397 0.028 1.88e-42
Height21 LDpred1 Inf 0.378 0.014 4.25e-148 0.390 0.028 6.17e-41
Height21 LDpred1 10FCVal 0.380 0.014 6.34e-150 0.383 0.028 2.33e-39
Height21 LDpred2 MultiPRS 0.440 0.014 2.09e-206 0.432 0.027 7.46e-51
Height21 LDpred2 10FCVal 0.431 0.014 2.19e-197 0.445 0.027 2.71e-54
Height21 LDpred2 PseudoVal 0.378 0.014 1.83e-148 0.394 0.028 6.43e-42
Height21 LDpred2 Inf 0.379 0.014 5.33e-149 0.395 0.028 5.92e-42
Height21 PRScs MultiPRS 0.435 0.014 4.30e-201 0.437 0.027 4.40e-52
Height21 PRScs 10FCVal 0.429 0.014 3.85e-195 0.434 0.027 2.21e-51
Height21 PRScs PseudoVal 0.436 0.014 1.70e-201 0.435 0.027 1.53e-51
Height21 pT+clump MultiPRS 0.399 0.014 3.07e-166 0.389 0.028 1.01e-40
Height21 pT+clump 10FCVal 0.387 0.014 4.03e-156 0.353 0.028 1.90e-33
Height21 SBayesR PseudoVal 0.428 0.014 2.12e-194 0.434 0.027 2.34e-51
Height21 SBLUP Inf 0.378 0.014 4.90e-148 0.387 0.028 2.32e-40
BMI21 All MultiPRS 0.367 0.014 2.08e-133 0.327 0.029 1.88e-27
BMI21 DBSLMM PseudoVal 0.354 0.014 1.97e-123 0.303 0.030 1.47e-23
BMI21 lassosum MultiPRS 0.361 0.014 1.89e-128 0.334 0.029 1.21e-28
BMI21 lassosum 10FCVal 0.352 0.014 3.69e-122 0.332 0.029 2.79e-28
BMI21 lassosum PseudoVal 0.288 0.015 1.08e-80 0.231 0.030 4.64e-14
BMI21 LDpred1 MultiPRS 0.349 0.015 7.25e-120 0.306 0.029 4.85e-24
BMI21 LDpred1 Inf 0.345 0.015 6.27e-117 0.298 0.030 8.50e-23
BMI21 LDpred1 10FCVal 0.336 0.015 1.04e-110 0.306 0.029 5.09e-24
BMI21 LDpred2 MultiPRS 0.357 0.014 1.02e-125 0.308 0.029 2.00e-24
BMI21 LDpred2 10FCVal 0.360 0.014 9.14e-128 0.315 0.029 1.84e-25
BMI21 LDpred2 PseudoVal 0.333 0.015 1.09e-108 0.290 0.030 9.52e-22
BMI21 LDpred2 Inf 0.333 0.015 6.02e-109 0.290 0.030 9.80e-22
BMI21 PRScs MultiPRS 0.354 0.014 8.88e-124 0.325 0.029 4.41e-27
BMI21 PRScs 10FCVal 0.353 0.014 1.69e-122 0.326 0.029 2.69e-27
BMI21 PRScs PseudoVal 0.347 0.015 8.41e-119 0.302 0.030 2.10e-23
BMI21 pT+clump MultiPRS 0.317 0.015 4.72e-98 0.295 0.030 2.36e-22
BMI21 pT+clump 10FCVal 0.310 0.015 1.99e-93 0.301 0.030 2.84e-23
BMI21 SBayesR PseudoVal 0.339 0.015 8.16e-113 0.290 0.030 1.09e-21
BMI21 SBLUP Inf 0.324 0.015 5.56e-103 0.299 0.030 6.00e-23
GCSE All MultiPRS 0.417 0.012 1.14e-244 0.347 0.025 1.87e-42
GCSE DBSLMM PseudoVal 0.401 0.012 1.23e-224 0.337 0.025 4.74e-40
GCSE lassosum MultiPRS 0.411 0.012 7.98e-237 0.347 0.025 1.61e-42
GCSE lassosum 10FCVal 0.407 0.012 4.55e-232 0.348 0.025 9.42e-43
GCSE lassosum PseudoVal 0.321 0.012 1.50e-139 0.276 0.025 6.05e-27
GCSE LDpred1 MultiPRS 0.409 0.012 2.61e-234 0.340 0.025 9.04e-41
GCSE LDpred1 Inf 0.408 0.012 1.33e-232 0.341 0.025 4.43e-41
GCSE LDpred1 10FCVal 0.402 0.012 1.72e-225 0.330 0.025 1.55e-38
GCSE LDpred2 MultiPRS 0.412 0.012 1.31e-238 0.339 0.025 1.49e-40
GCSE LDpred2 10FCVal 0.412 0.012 2.30e-237 0.342 0.025 2.45e-41
GCSE LDpred2 PseudoVal 0.406 0.012 4.26e-230 0.332 0.025 5.58e-39
GCSE LDpred2 Inf 0.405 0.012 1.23e-229 0.331 0.025 1.34e-38
GCSE PRScs MultiPRS 0.413 0.012 3.03e-239 0.346 0.025 2.86e-42
GCSE PRScs 10FCVal 0.410 0.012 7.43e-236 0.341 0.025 5.82e-41
GCSE PRScs PseudoVal 0.397 0.012 5.80e-220 0.351 0.025 1.34e-43
GCSE pT+clump MultiPRS 0.381 0.012 1.40e-200 0.328 0.025 5.13e-38
GCSE pT+clump 10FCVal 0.373 0.012 6.29e-192 0.311 0.025 3.63e-34
GCSE SBayesR PseudoVal 0.397 0.012 4.85e-219 0.331 0.025 1.23e-38
GCSE SBLUP Inf 0.400 0.012 1.37e-222 0.335 0.025 1.61e-39
ADHD All MultiPRS 0.115 0.013 4.12e-20 0.186 0.025 8.96e-14
ADHD DBSLMM PseudoVal 0.114 0.013 1.00e-19 0.184 0.025 2.11e-13
ADHD lassosum MultiPRS 0.117 0.013 1.09e-20 0.199 0.025 1.69e-15
ADHD lassosum PseudoVal 0.077 0.013 1.17e-09 0.118 0.025 2.58e-06
ADHD lassosum 10FCVal 0.118 0.013 7.06e-21 0.194 0.025 8.52e-15
ADHD LDpred1 MultiPRS 0.117 0.013 1.13e-20 0.191 0.025 1.83e-14
ADHD LDpred1 Inf 0.115 0.013 4.11e-20 0.191 0.025 1.77e-14
ADHD LDpred1 10FCVal 0.118 0.013 6.01e-21 0.190 0.025 2.60e-14
ADHD LDpred2 MultiPRS 0.114 0.013 7.89e-20 0.199 0.025 1.81e-15
ADHD LDpred2 10FCVal 0.118 0.013 4.58e-21 0.198 0.025 1.97e-15
ADHD LDpred2 PseudoVal 0.115 0.013 6.15e-20 0.195 0.025 6.11e-15
ADHD LDpred2 Inf 0.115 0.013 3.98e-20 0.194 0.025 6.97e-15
ADHD PRScs MultiPRS 0.113 0.013 2.60e-19 0.203 0.025 4.72e-16
ADHD PRScs 10FCVal 0.114 0.013 1.06e-19 0.207 0.025 9.33e-17
ADHD PRScs PseudoVal 0.109 0.013 4.15e-18 0.189 0.025 3.84e-14
ADHD pT+clump MultiPRS 0.096 0.013 2.43e-14 0.162 0.025 1.09e-10
ADHD pT+clump 10FCVal 0.094 0.013 7.96e-14 0.150 0.025 2.46e-09
ADHD SBayesR PseudoVal 0.091 0.013 4.32e-13 0.155 0.025 5.89e-10
ADHD SBLUP Inf 0.116 0.013 3.56e-20 0.193 0.025 1.06e-14

Show cross-validation results compared to pT+clump

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results compared to pT+clump

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show difference results table

Difference between methods in TEDS with 1KG reference
Phenotype Model 1 Test Model 2 Test Model 1 CrossVal R Model 2 CrossVal R CrossVal R Diff CrossVal R Diff P Model 1 IndepVal R Model 2 IndepVal R IndepVal R Diff IndepVal R Diff P
Height21 LDpred2.PseudoVal All.MultiPRS 0.378 0.447 -0.068 2.06e-04 0.394 0.443 -0.049 9.86e-04
Height21 pT+clump.10FCVal All.MultiPRS 0.387 0.447 -0.059 1.38e-03 0.353 0.443 -0.089 1.34e-09
Height21 LDpred2.MultiPRS All.MultiPRS 0.440 0.447 -0.006 7.22e-01 0.432 0.443 -0.011 1.53e-01
Height21 PRScs.PseudoVal All.MultiPRS 0.436 0.447 -0.011 5.35e-01 0.435 0.443 -0.008 2.60e-01
Height21 LDpred1.Inf All.MultiPRS 0.378 0.447 -0.069 1.85e-04 0.390 0.443 -0.053 2.98e-04
Height21 PRScs.MultiPRS All.MultiPRS 0.435 0.447 -0.012 1.17e-03 0.437 0.443 -0.006 3.71e-01
Height21 LDpred2.Inf All.MultiPRS 0.379 0.447 -0.068 2.36e-04 0.395 0.443 -0.048 9.47e-04
Height21 lassosum.PseudoVal All.MultiPRS 0.357 0.447 -0.089 1.52e-06 0.354 0.443 -0.089 9.71e-08
Height21 LDpred2.10FCVal All.MultiPRS 0.431 0.447 -0.015 3.99e-01 0.445 0.443 0.003 7.50e-01
Height21 lassosum.MultiPRS All.MultiPRS 0.440 0.447 -0.007 6.99e-01 0.431 0.443 -0.012 3.78e-02
Height21 LDpred1.10FCVal All.MultiPRS 0.380 0.447 -0.067 2.88e-04 0.383 0.443 -0.060 7.89e-05
Height21 All.MultiPRS All.MultiPRS 0.447 0.447 0.000 1.00e+00 0.443 0.443 0.000 1.00e+00
Height21 SBayesR.PseudoVal All.MultiPRS 0.428 0.447 -0.018 3.14e-01 0.434 0.443 -0.009 3.23e-01
Height21 LDpred1.MultiPRS All.MultiPRS 0.384 0.447 -0.063 6.29e-04 0.397 0.443 -0.046 1.03e-03
Height21 pT+clump.MultiPRS All.MultiPRS 0.399 0.447 -0.048 8.50e-03 0.389 0.443 -0.054 7.39e-06
Height21 lassosum.10FCVal All.MultiPRS 0.435 0.447 -0.012 5.14e-01 0.425 0.443 -0.018 1.65e-02
Height21 PRScs.10FCVal All.MultiPRS 0.429 0.447 -0.017 3.34e-01 0.434 0.443 -0.009 2.44e-01
Height21 DBSLMM.PseudoVal All.MultiPRS 0.417 0.447 -0.030 9.92e-02 0.428 0.443 -0.014 1.51e-01
Height21 SBLUP.Inf All.MultiPRS 0.378 0.447 -0.069 1.82e-04 0.387 0.443 -0.056 2.84e-04
Height21 SBayesR.PseudoVal DBSLMM.PseudoVal 0.428 0.417 0.012 1.08e-01 0.434 0.428 0.006 6.83e-01
Height21 LDpred2.Inf DBSLMM.PseudoVal 0.379 0.417 -0.038 1.96e-09 0.395 0.428 -0.034 8.97e-03
Height21 pT+clump.10FCVal DBSLMM.PseudoVal 0.387 0.417 -0.029 1.69e-03 0.353 0.428 -0.075 5.64e-05
Height21 PRScs.10FCVal DBSLMM.PseudoVal 0.429 0.417 0.013 2.65e-02 0.434 0.428 0.006 5.88e-01
Height21 PRScs.PseudoVal DBSLMM.PseudoVal 0.436 0.417 0.019 1.39e-04 0.435 0.428 0.006 5.00e-01
Height21 pT+clump.MultiPRS DBSLMM.PseudoVal 0.399 0.417 -0.018 3.30e-01 0.389 0.428 -0.040 3.94e-03
Height21 LDpred1.Inf DBSLMM.PseudoVal 0.378 0.417 -0.039 4.36e-10 0.390 0.428 -0.039 1.86e-03
Height21 lassosum.MultiPRS DBSLMM.PseudoVal 0.440 0.417 0.023 2.06e-01 0.431 0.428 0.002 8.45e-01
Height21 LDpred2.10FCVal DBSLMM.PseudoVal 0.431 0.417 0.015 6.35e-03 0.445 0.428 0.017 1.08e-01
Height21 lassosum.PseudoVal DBSLMM.PseudoVal 0.357 0.417 -0.059 6.20e-08 0.354 0.428 -0.075 3.14e-04
Height21 LDpred1.10FCVal DBSLMM.PseudoVal 0.380 0.417 -0.037 8.68e-08 0.383 0.428 -0.046 1.34e-03
Height21 LDpred1.MultiPRS DBSLMM.PseudoVal 0.384 0.417 -0.033 7.50e-02 0.397 0.428 -0.032 1.13e-02
Height21 PRScs.MultiPRS DBSLMM.PseudoVal 0.435 0.417 0.018 3.13e-01 0.437 0.428 0.008 3.43e-01
Height21 All.MultiPRS DBSLMM.PseudoVal 0.447 0.417 0.030 9.92e-02 0.443 0.428 0.014 1.51e-01
Height21 LDpred2.PseudoVal DBSLMM.PseudoVal 0.378 0.417 -0.038 1.30e-09 0.394 0.428 -0.034 8.94e-03
Height21 DBSLMM.PseudoVal DBSLMM.PseudoVal 0.417 0.417 0.000 1.00e+00 0.428 0.428 0.000 1.00e+00
Height21 LDpred2.MultiPRS DBSLMM.PseudoVal 0.440 0.417 0.024 1.97e-01 0.432 0.428 0.004 7.74e-01
Height21 lassosum.10FCVal DBSLMM.PseudoVal 0.435 0.417 0.018 5.36e-03 0.425 0.428 -0.003 7.82e-01
Height21 SBLUP.Inf DBSLMM.PseudoVal 0.378 0.417 -0.039 3.12e-10 0.387 0.428 -0.041 1.27e-03
Height21 SBayesR.PseudoVal lassosum.MultiPRS 0.428 0.440 -0.011 5.35e-01 0.434 0.431 0.004 7.46e-01
Height21 LDpred2.10FCVal lassosum.MultiPRS 0.431 0.440 -0.008 6.49e-01 0.445 0.431 0.015 1.25e-01
Height21 LDpred1.10FCVal lassosum.MultiPRS 0.380 0.440 -0.060 1.23e-03 0.383 0.431 -0.048 2.96e-03
Height21 LDpred2.Inf lassosum.MultiPRS 0.379 0.440 -0.061 1.07e-03 0.395 0.431 -0.036 1.88e-02
Height21 PRScs.10FCVal lassosum.MultiPRS 0.429 0.440 -0.011 5.61e-01 0.434 0.431 0.004 6.32e-01
Height21 PRScs.MultiPRS lassosum.MultiPRS 0.435 0.440 -0.005 7.98e-01 0.437 0.431 0.006 3.51e-01
Height21 pT+clump.MultiPRS lassosum.MultiPRS 0.399 0.440 -0.041 2.69e-02 0.389 0.431 -0.042 1.31e-03
Height21 lassosum.MultiPRS lassosum.MultiPRS 0.440 0.440 0.000 1.00e+00 0.431 0.431 0.000 1.00e+00
Height21 lassosum.10FCVal lassosum.MultiPRS 0.435 0.440 -0.005 7.90e-01 0.425 0.431 -0.005 2.83e-01
Height21 LDpred2.MultiPRS lassosum.MultiPRS 0.440 0.440 0.001 9.75e-01 0.432 0.431 0.002 8.71e-01
Height21 LDpred1.MultiPRS lassosum.MultiPRS 0.384 0.440 -0.056 2.53e-03 0.397 0.431 -0.034 2.33e-02
Height21 LDpred2.PseudoVal lassosum.MultiPRS 0.378 0.440 -0.061 9.49e-04 0.394 0.431 -0.036 1.92e-02
Height21 LDpred1.Inf lassosum.MultiPRS 0.378 0.440 -0.062 8.53e-04 0.390 0.431 -0.041 7.00e-03
Height21 pT+clump.10FCVal lassosum.MultiPRS 0.387 0.440 -0.052 4.46e-03 0.353 0.431 -0.077 2.15e-06
Height21 lassosum.PseudoVal lassosum.MultiPRS 0.357 0.440 -0.083 9.39e-06 0.354 0.431 -0.077 1.98e-06
Height21 SBLUP.Inf lassosum.MultiPRS 0.378 0.440 -0.062 8.41e-04 0.387 0.431 -0.043 5.74e-03
Height21 DBSLMM.PseudoVal lassosum.MultiPRS 0.417 0.440 -0.023 2.06e-01 0.428 0.431 -0.002 8.45e-01
Height21 All.MultiPRS lassosum.MultiPRS 0.447 0.440 0.007 6.99e-01 0.443 0.431 0.012 3.78e-02
Height21 PRScs.PseudoVal lassosum.MultiPRS 0.436 0.440 -0.004 8.16e-01 0.435 0.431 0.004 5.60e-01
Height21 LDpred1.Inf lassosum.10FCVal 0.378 0.435 -0.057 2.80e-11 0.390 0.425 -0.035 3.47e-02
Height21 PRScs.10FCVal lassosum.10FCVal 0.429 0.435 -0.006 1.40e-01 0.434 0.425 0.009 2.25e-01
Height21 LDpred2.MultiPRS lassosum.10FCVal 0.440 0.435 0.005 7.67e-01 0.432 0.425 0.007 4.63e-01
Height21 lassosum.10FCVal lassosum.10FCVal 0.435 0.435 0.000 1.00e+00 0.425 0.425 0.000 1.00e+00
Height21 PRScs.PseudoVal lassosum.10FCVal 0.436 0.435 0.001 8.87e-01 0.435 0.425 0.010 2.06e-01
Height21 DBSLMM.PseudoVal lassosum.10FCVal 0.417 0.435 -0.018 5.36e-03 0.428 0.425 0.003 7.82e-01
Height21 SBLUP.Inf lassosum.10FCVal 0.378 0.435 -0.057 1.04e-10 0.387 0.425 -0.038 2.97e-02
Height21 LDpred2.Inf lassosum.10FCVal 0.379 0.435 -0.056 2.98e-11 0.395 0.425 -0.030 6.61e-02
Height21 pT+clump.10FCVal lassosum.10FCVal 0.387 0.435 -0.048 7.29e-09 0.353 0.425 -0.072 8.44e-06
Height21 LDpred2.10FCVal lassosum.10FCVal 0.431 0.435 -0.003 5.20e-01 0.445 0.425 0.020 5.12e-02
Height21 lassosum.MultiPRS lassosum.10FCVal 0.440 0.435 0.005 7.90e-01 0.431 0.425 0.005 2.83e-01
Height21 LDpred1.10FCVal lassosum.10FCVal 0.380 0.435 -0.055 3.22e-10 0.383 0.425 -0.042 1.60e-02
Height21 All.MultiPRS lassosum.10FCVal 0.447 0.435 0.012 5.14e-01 0.443 0.425 0.018 1.65e-02
Height21 SBayesR.PseudoVal lassosum.10FCVal 0.428 0.435 -0.006 2.47e-01 0.434 0.425 0.009 4.12e-01
Height21 lassosum.PseudoVal lassosum.10FCVal 0.357 0.435 -0.078 3.45e-24 0.354 0.425 -0.071 1.41e-06
Height21 pT+clump.MultiPRS lassosum.10FCVal 0.399 0.435 -0.036 4.78e-02 0.389 0.425 -0.036 6.07e-03
Height21 LDpred2.PseudoVal lassosum.10FCVal 0.378 0.435 -0.057 3.18e-11 0.394 0.425 -0.031 6.83e-02
Height21 LDpred1.MultiPRS lassosum.10FCVal 0.384 0.435 -0.051 5.47e-03 0.397 0.425 -0.028 8.65e-02
Height21 PRScs.MultiPRS lassosum.10FCVal 0.435 0.435 0.000 9.92e-01 0.437 0.425 0.012 1.15e-01
Height21 lassosum.PseudoVal lassosum.PseudoVal 0.357 0.357 0.000 1.00e+00 0.354 0.354 0.000 1.00e+00
Height21 pT+clump.MultiPRS lassosum.PseudoVal 0.399 0.357 0.041 2.80e-02 0.389 0.354 0.035 7.68e-02
Height21 LDpred2.Inf lassosum.PseudoVal 0.379 0.357 0.022 1.00e-01 0.395 0.354 0.041 1.07e-01
Height21 SBayesR.PseudoVal lassosum.PseudoVal 0.428 0.357 0.071 1.23e-20 0.434 0.354 0.080 1.23e-07
Height21 PRScs.MultiPRS lassosum.PseudoVal 0.435 0.357 0.078 3.06e-05 0.437 0.354 0.083 4.73e-07
Height21 SBLUP.Inf lassosum.PseudoVal 0.378 0.357 0.020 1.32e-01 0.387 0.354 0.033 2.01e-01
Height21 lassosum.MultiPRS lassosum.PseudoVal 0.440 0.357 0.083 9.39e-06 0.431 0.354 0.077 1.98e-06
Height21 PRScs.10FCVal lassosum.PseudoVal 0.429 0.357 0.072 2.39e-20 0.434 0.354 0.080 1.34e-07
Height21 LDpred2.MultiPRS lassosum.PseudoVal 0.440 0.357 0.083 8.31e-06 0.432 0.354 0.078 9.14e-06
Height21 PRScs.PseudoVal lassosum.PseudoVal 0.436 0.357 0.078 4.38e-19 0.435 0.354 0.081 1.75e-06
Height21 LDpred2.PseudoVal lassosum.PseudoVal 0.378 0.357 0.021 1.13e-01 0.394 0.354 0.041 1.11e-01
Height21 LDpred1.MultiPRS lassosum.PseudoVal 0.384 0.357 0.027 1.58e-01 0.397 0.354 0.043 8.58e-02
Height21 pT+clump.10FCVal lassosum.PseudoVal 0.387 0.357 0.030 4.48e-03 0.353 0.354 0.000 9.86e-01
Height21 All.MultiPRS lassosum.PseudoVal 0.447 0.357 0.089 1.52e-06 0.443 0.354 0.089 9.71e-08
Height21 LDpred1.Inf lassosum.PseudoVal 0.378 0.357 0.021 1.22e-01 0.390 0.354 0.036 1.56e-01
Height21 DBSLMM.PseudoVal lassosum.PseudoVal 0.417 0.357 0.059 6.20e-08 0.428 0.354 0.075 3.14e-04
Height21 LDpred1.10FCVal lassosum.PseudoVal 0.380 0.357 0.023 8.22e-02 0.383 0.354 0.029 2.57e-01
Height21 lassosum.10FCVal lassosum.PseudoVal 0.435 0.357 0.078 3.45e-24 0.425 0.354 0.071 1.41e-06
Height21 LDpred2.10FCVal lassosum.PseudoVal 0.431 0.357 0.074 6.73e-13 0.445 0.354 0.092 4.02e-06
Height21 LDpred2.10FCVal LDpred1.MultiPRS 0.431 0.384 0.048 9.75e-03 0.445 0.397 0.049 1.38e-05
Height21 PRScs.PseudoVal LDpred1.MultiPRS 0.436 0.384 0.052 4.89e-03 0.435 0.397 0.038 3.68e-03
Height21 LDpred2.Inf LDpred1.MultiPRS 0.379 0.384 -0.005 7.89e-01 0.395 0.397 -0.002 7.95e-01
Height21 pT+clump.10FCVal LDpred1.MultiPRS 0.387 0.384 0.003 8.59e-01 0.353 0.397 -0.043 6.22e-02
Height21 SBayesR.PseudoVal LDpred1.MultiPRS 0.428 0.384 0.045 1.57e-02 0.434 0.397 0.037 5.29e-02
Height21 All.MultiPRS LDpred1.MultiPRS 0.447 0.384 0.063 6.29e-04 0.443 0.397 0.046 1.03e-03
Height21 LDpred1.10FCVal LDpred1.MultiPRS 0.380 0.384 -0.004 8.34e-01 0.383 0.397 -0.014 1.69e-02
Height21 LDpred1.MultiPRS LDpred1.MultiPRS 0.384 0.384 0.000 1.00e+00 0.397 0.397 0.000 1.00e+00
Height21 PRScs.10FCVal LDpred1.MultiPRS 0.429 0.384 0.045 1.38e-02 0.434 0.397 0.037 1.33e-02
Height21 lassosum.10FCVal LDpred1.MultiPRS 0.435 0.384 0.051 5.47e-03 0.425 0.397 0.028 8.65e-02
Height21 pT+clump.MultiPRS LDpred1.MultiPRS 0.399 0.384 0.015 4.29e-01 0.389 0.397 -0.008 6.69e-01
Height21 LDpred1.Inf LDpred1.MultiPRS 0.378 0.384 -0.006 7.45e-01 0.390 0.397 -0.007 2.65e-01
Height21 lassosum.MultiPRS LDpred1.MultiPRS 0.440 0.384 0.056 2.53e-03 0.431 0.397 0.034 2.33e-02
Height21 PRScs.MultiPRS LDpred1.MultiPRS 0.435 0.384 0.051 5.49e-03 0.437 0.397 0.040 1.83e-03
Height21 lassosum.PseudoVal LDpred1.MultiPRS 0.357 0.384 -0.027 1.58e-01 0.354 0.397 -0.043 8.58e-02
Height21 LDpred2.PseudoVal LDpred1.MultiPRS 0.378 0.384 -0.006 7.63e-01 0.394 0.397 -0.002 7.80e-01
Height21 DBSLMM.PseudoVal LDpred1.MultiPRS 0.417 0.384 0.033 7.50e-02 0.428 0.397 0.032 1.13e-02
Height21 LDpred2.MultiPRS LDpred1.MultiPRS 0.440 0.384 0.056 2.61e-03 0.432 0.397 0.035 1.90e-02
Height21 SBLUP.Inf LDpred1.MultiPRS 0.378 0.384 -0.006 7.42e-01 0.387 0.397 -0.009 2.18e-01
Height21 All.MultiPRS LDpred1.Inf 0.447 0.378 0.069 1.85e-04 0.443 0.390 0.053 2.98e-04
Height21 LDpred2.PseudoVal LDpred1.Inf 0.378 0.378 0.000 9.06e-01 0.394 0.390 0.004 5.36e-01
Height21 SBayesR.PseudoVal LDpred1.Inf 0.428 0.378 0.051 7.00e-07 0.434 0.390 0.044 2.50e-02
Height21 LDpred2.MultiPRS LDpred1.Inf 0.440 0.378 0.062 7.58e-04 0.432 0.390 0.042 6.15e-03
Height21 PRScs.PseudoVal LDpred1.Inf 0.436 0.378 0.058 2.65e-17 0.435 0.390 0.045 6.45e-04
Height21 LDpred1.Inf LDpred1.Inf 0.378 0.378 0.000 1.00e+00 0.390 0.390 0.000 1.00e+00
Height21 pT+clump.10FCVal LDpred1.Inf 0.387 0.378 0.009 4.14e-01 0.353 0.390 -0.036 1.15e-01
Height21 PRScs.MultiPRS LDpred1.Inf 0.435 0.378 0.057 1.97e-03 0.437 0.390 0.047 3.01e-04
Height21 lassosum.10FCVal LDpred1.Inf 0.435 0.378 0.057 2.80e-11 0.425 0.390 0.035 3.47e-02
Height21 pT+clump.MultiPRS LDpred1.Inf 0.399 0.378 0.021 2.63e-01 0.389 0.390 -0.001 9.56e-01
Height21 LDpred1.MultiPRS LDpred1.Inf 0.384 0.378 0.006 7.45e-01 0.397 0.390 0.007 2.65e-01
Height21 PRScs.10FCVal LDpred1.Inf 0.429 0.378 0.051 1.03e-10 0.434 0.390 0.044 3.69e-03
Height21 LDpred2.Inf LDpred1.Inf 0.379 0.378 0.001 7.67e-01 0.395 0.390 0.005 5.15e-01
Height21 SBLUP.Inf LDpred1.Inf 0.378 0.378 0.000 9.82e-01 0.387 0.390 -0.003 6.93e-01
Height21 DBSLMM.PseudoVal LDpred1.Inf 0.417 0.378 0.039 4.36e-10 0.428 0.390 0.039 1.86e-03
Height21 lassosum.MultiPRS LDpred1.Inf 0.440 0.378 0.062 8.53e-04 0.431 0.390 0.041 7.00e-03
Height21 LDpred1.10FCVal LDpred1.Inf 0.380 0.378 0.002 6.74e-01 0.383 0.390 -0.007 4.93e-01
Height21 lassosum.PseudoVal LDpred1.Inf 0.357 0.378 -0.021 1.22e-01 0.354 0.390 -0.036 1.56e-01
Height21 LDpred2.10FCVal LDpred1.Inf 0.431 0.378 0.054 4.13e-19 0.445 0.390 0.056 9.40e-07
Height21 LDpred1.Inf LDpred1.10FCVal 0.378 0.380 -0.002 6.74e-01 0.390 0.383 0.007 4.93e-01
Height21 PRScs.MultiPRS LDpred1.10FCVal 0.435 0.380 0.055 2.85e-03 0.437 0.383 0.054 1.84e-04
Height21 LDpred1.10FCVal LDpred1.10FCVal 0.380 0.380 0.000 1.00e+00 0.383 0.383 0.000 1.00e+00
Height21 All.MultiPRS LDpred1.10FCVal 0.447 0.380 0.067 2.88e-04 0.443 0.383 0.060 7.89e-05
Height21 SBayesR.PseudoVal LDpred1.10FCVal 0.428 0.380 0.048 1.66e-06 0.434 0.383 0.051 1.04e-02
Height21 DBSLMM.PseudoVal LDpred1.10FCVal 0.417 0.380 0.037 8.68e-08 0.428 0.383 0.046 1.34e-03
Height21 pT+clump.MultiPRS LDpred1.10FCVal 0.399 0.380 0.019 3.16e-01 0.389 0.383 0.006 7.48e-01
Height21 lassosum.MultiPRS LDpred1.10FCVal 0.440 0.380 0.060 1.23e-03 0.431 0.383 0.048 2.96e-03
Height21 PRScs.10FCVal LDpred1.10FCVal 0.429 0.380 0.049 1.78e-09 0.434 0.383 0.052 1.73e-03
Height21 lassosum.PseudoVal LDpred1.10FCVal 0.357 0.380 -0.023 8.22e-02 0.354 0.383 -0.029 2.57e-01
Height21 SBLUP.Inf LDpred1.10FCVal 0.378 0.380 -0.002 6.70e-01 0.387 0.383 0.005 6.67e-01
Height21 LDpred2.PseudoVal LDpred1.10FCVal 0.378 0.380 -0.002 7.64e-01 0.394 0.383 0.012 3.19e-01
Height21 pT+clump.10FCVal LDpred1.10FCVal 0.387 0.380 0.007 5.35e-01 0.353 0.383 -0.029 2.26e-01
Height21 LDpred2.MultiPRS LDpred1.10FCVal 0.440 0.380 0.060 1.20e-03 0.432 0.383 0.049 2.21e-03
Height21 PRScs.PseudoVal LDpred1.10FCVal 0.436 0.380 0.056 1.75e-14 0.435 0.383 0.052 4.02e-04
Height21 LDpred2.10FCVal LDpred1.10FCVal 0.431 0.380 0.051 7.60e-15 0.445 0.383 0.063 1.48e-06
Height21 LDpred1.MultiPRS LDpred1.10FCVal 0.384 0.380 0.004 8.34e-01 0.397 0.383 0.014 1.69e-02
Height21 LDpred2.Inf LDpred1.10FCVal 0.379 0.380 -0.001 8.49e-01 0.395 0.383 0.012 3.15e-01
Height21 lassosum.10FCVal LDpred1.10FCVal 0.435 0.380 0.055 3.22e-10 0.425 0.383 0.042 1.60e-02
Height21 LDpred1.Inf LDpred2.MultiPRS 0.378 0.440 -0.062 7.58e-04 0.390 0.432 -0.042 6.15e-03
Height21 DBSLMM.PseudoVal LDpred2.MultiPRS 0.417 0.440 -0.024 1.97e-01 0.428 0.432 -0.004 7.74e-01
Height21 SBLUP.Inf LDpred2.MultiPRS 0.378 0.440 -0.063 7.43e-04 0.387 0.432 -0.045 4.87e-03
Height21 LDpred2.Inf LDpred2.MultiPRS 0.379 0.440 -0.061 9.20e-04 0.395 0.432 -0.038 1.11e-02
Height21 pT+clump.10FCVal LDpred2.MultiPRS 0.387 0.440 -0.053 3.99e-03 0.353 0.432 -0.079 1.04e-05
Height21 LDpred2.10FCVal LDpred2.MultiPRS 0.431 0.440 -0.009 6.26e-01 0.445 0.432 0.013 6.92e-02
Height21 PRScs.PseudoVal LDpred2.MultiPRS 0.436 0.440 -0.005 7.92e-01 0.435 0.432 0.003 7.59e-01
Height21 LDpred1.10FCVal LDpred2.MultiPRS 0.380 0.440 -0.060 1.20e-03 0.383 0.432 -0.049 2.21e-03
Height21 All.MultiPRS LDpred2.MultiPRS 0.447 0.440 0.006 7.22e-01 0.443 0.432 0.011 1.53e-01
Height21 SBayesR.PseudoVal LDpred2.MultiPRS 0.428 0.440 -0.012 5.15e-01 0.434 0.432 0.002 8.66e-01
Height21 lassosum.PseudoVal LDpred2.MultiPRS 0.357 0.440 -0.083 8.31e-06 0.354 0.432 -0.078 9.14e-06
Height21 pT+clump.MultiPRS LDpred2.MultiPRS 0.399 0.440 -0.042 2.41e-02 0.389 0.432 -0.043 3.36e-03
Height21 lassosum.MultiPRS LDpred2.MultiPRS 0.440 0.440 -0.001 9.75e-01 0.431 0.432 -0.002 8.71e-01
Height21 PRScs.10FCVal LDpred2.MultiPRS 0.429 0.440 -0.011 5.42e-01 0.434 0.432 0.002 8.22e-01
Height21 PRScs.MultiPRS LDpred2.MultiPRS 0.435 0.440 -0.005 7.75e-01 0.437 0.432 0.005 5.78e-01
Height21 lassosum.10FCVal LDpred2.MultiPRS 0.435 0.440 -0.005 7.67e-01 0.425 0.432 -0.007 4.63e-01
Height21 LDpred2.PseudoVal LDpred2.MultiPRS 0.378 0.440 -0.062 8.14e-04 0.394 0.432 -0.038 1.14e-02
Height21 LDpred1.MultiPRS LDpred2.MultiPRS 0.384 0.440 -0.056 2.61e-03 0.397 0.432 -0.035 1.90e-02
Height21 LDpred2.MultiPRS LDpred2.MultiPRS 0.440 0.440 0.000 1.00e+00 0.432 0.432 0.000 1.00e+00
Height21 LDpred1.Inf LDpred2.10FCVal 0.378 0.431 -0.054 4.13e-19 0.390 0.445 -0.056 9.40e-07
Height21 PRScs.MultiPRS LDpred2.10FCVal 0.435 0.431 0.004 8.40e-01 0.437 0.445 -0.008 2.96e-01
Height21 LDpred2.MultiPRS LDpred2.10FCVal 0.440 0.431 0.009 6.26e-01 0.432 0.445 -0.013 6.92e-02
Height21 PRScs.PseudoVal LDpred2.10FCVal 0.436 0.431 0.004 3.49e-01 0.435 0.445 -0.011 2.04e-01
Height21 LDpred2.10FCVal LDpred2.10FCVal 0.431 0.431 0.000 1.00e+00 0.445 0.445 0.000 1.00e+00
Height21 lassosum.MultiPRS LDpred2.10FCVal 0.440 0.431 0.008 6.49e-01 0.431 0.445 -0.015 1.25e-01
Height21 LDpred1.10FCVal LDpred2.10FCVal 0.380 0.431 -0.051 7.60e-15 0.383 0.445 -0.063 1.48e-06
Height21 All.MultiPRS LDpred2.10FCVal 0.447 0.431 0.015 3.99e-01 0.443 0.445 -0.003 7.50e-01
Height21 SBayesR.PseudoVal LDpred2.10FCVal 0.428 0.431 -0.003 6.71e-01 0.434 0.445 -0.011 4.04e-01
Height21 DBSLMM.PseudoVal LDpred2.10FCVal 0.417 0.431 -0.015 6.35e-03 0.428 0.445 -0.017 1.08e-01
Height21 pT+clump.MultiPRS LDpred2.10FCVal 0.399 0.431 -0.033 7.43e-02 0.389 0.445 -0.057 1.04e-04
Height21 lassosum.10FCVal LDpred2.10FCVal 0.435 0.431 0.003 5.20e-01 0.425 0.445 -0.020 5.12e-02
Height21 PRScs.10FCVal LDpred2.10FCVal 0.429 0.431 -0.002 6.60e-01 0.434 0.445 -0.011 2.54e-01
Height21 lassosum.PseudoVal LDpred2.10FCVal 0.357 0.431 -0.074 6.73e-13 0.354 0.445 -0.092 4.02e-06
Height21 SBLUP.Inf LDpred2.10FCVal 0.378 0.431 -0.054 4.70e-18 0.387 0.445 -0.058 6.59e-07
Height21 LDpred2.PseudoVal LDpred2.10FCVal 0.378 0.431 -0.053 6.53e-26 0.394 0.445 -0.051 2.50e-07
Height21 pT+clump.10FCVal LDpred2.10FCVal 0.387 0.431 -0.044 3.65e-06 0.353 0.445 -0.092 1.17e-06
Height21 LDpred2.Inf LDpred2.10FCVal 0.379 0.431 -0.053 2.14e-25 0.395 0.445 -0.051 2.47e-07
Height21 LDpred1.MultiPRS LDpred2.10FCVal 0.384 0.431 -0.048 9.75e-03 0.397 0.445 -0.049 1.38e-05
Height21 lassosum.PseudoVal LDpred2.PseudoVal 0.357 0.378 -0.021 1.13e-01 0.354 0.394 -0.041 1.11e-01
Height21 SBLUP.Inf LDpred2.PseudoVal 0.378 0.378 -0.001 8.87e-01 0.387 0.394 -0.007 3.14e-01
Height21 SBayesR.PseudoVal LDpred2.PseudoVal 0.428 0.378 0.050 7.66e-07 0.434 0.394 0.040 4.63e-02
Height21 All.MultiPRS LDpred2.PseudoVal 0.447 0.378 0.068 2.06e-04 0.443 0.394 0.049 9.86e-04
Height21 PRScs.PseudoVal LDpred2.PseudoVal 0.436 0.378 0.057 6.26e-17 0.435 0.394 0.040 2.91e-03
Height21 lassosum.MultiPRS LDpred2.PseudoVal 0.440 0.378 0.061 9.49e-04 0.431 0.394 0.036 1.92e-02
Height21 PRScs.MultiPRS LDpred2.PseudoVal 0.435 0.378 0.057 2.14e-03 0.437 0.394 0.043 1.55e-03
Height21 LDpred2.MultiPRS LDpred2.PseudoVal 0.440 0.378 0.062 8.14e-04 0.432 0.394 0.038 1.14e-02
Height21 PRScs.10FCVal LDpred2.PseudoVal 0.429 0.378 0.051 1.04e-10 0.434 0.394 0.040 1.04e-02
Height21 LDpred2.PseudoVal LDpred2.PseudoVal 0.378 0.378 0.000 1.00e+00 0.394 0.394 0.000 1.00e+00
Height21 pT+clump.MultiPRS LDpred2.PseudoVal 0.399 0.378 0.020 2.73e-01 0.389 0.394 -0.005 7.70e-01
Height21 pT+clump.10FCVal LDpred2.PseudoVal 0.387 0.378 0.009 4.38e-01 0.353 0.394 -0.041 8.21e-02
Height21 lassosum.10FCVal LDpred2.PseudoVal 0.435 0.378 0.057 3.18e-11 0.425 0.394 0.031 6.83e-02
Height21 LDpred1.Inf LDpred2.PseudoVal 0.378 0.378 0.000 9.06e-01 0.390 0.394 -0.004 5.36e-01
Height21 LDpred1.MultiPRS LDpred2.PseudoVal 0.384 0.378 0.006 7.63e-01 0.397 0.394 0.002 7.80e-01
Height21 LDpred1.10FCVal LDpred2.PseudoVal 0.380 0.378 0.002 7.64e-01 0.383 0.394 -0.012 3.19e-01
Height21 LDpred2.Inf LDpred2.PseudoVal 0.379 0.378 0.001 1.63e-01 0.395 0.394 0.000 8.52e-01
Height21 LDpred2.10FCVal LDpred2.PseudoVal 0.431 0.378 0.053 6.53e-26 0.445 0.394 0.051 2.50e-07
Height21 DBSLMM.PseudoVal LDpred2.PseudoVal 0.417 0.378 0.038 1.30e-09 0.428 0.394 0.034 8.94e-03
Height21 pT+clump.MultiPRS LDpred2.Inf 0.399 0.379 0.020 2.88e-01 0.389 0.395 -0.006 7.61e-01
Height21 lassosum.MultiPRS LDpred2.Inf 0.440 0.379 0.061 1.07e-03 0.431 0.395 0.036 1.88e-02
Height21 SBayesR.PseudoVal LDpred2.Inf 0.428 0.379 0.050 8.46e-07 0.434 0.395 0.040 4.52e-02
Height21 All.MultiPRS LDpred2.Inf 0.447 0.379 0.068 2.36e-04 0.443 0.395 0.048 9.47e-04
Height21 SBLUP.Inf LDpred2.Inf 0.378 0.379 -0.001 7.48e-01 0.387 0.395 -0.007 3.05e-01
Height21 LDpred2.PseudoVal LDpred2.Inf 0.378 0.379 -0.001 1.63e-01 0.394 0.395 0.000 8.52e-01
Height21 PRScs.MultiPRS LDpred2.Inf 0.435 0.379 0.056 2.40e-03 0.437 0.395 0.042 1.35e-03
Height21 LDpred2.MultiPRS LDpred2.Inf 0.440 0.379 0.061 9.20e-04 0.432 0.395 0.038 1.11e-02
Height21 PRScs.10FCVal LDpred2.Inf 0.429 0.379 0.050 8.68e-11 0.434 0.395 0.040 9.54e-03
Height21 LDpred1.Inf LDpred2.Inf 0.378 0.379 -0.001 7.67e-01 0.390 0.395 -0.005 5.15e-01
Height21 LDpred1.MultiPRS LDpred2.Inf 0.384 0.379 0.005 7.89e-01 0.397 0.395 0.002 7.95e-01
Height21 pT+clump.10FCVal LDpred2.Inf 0.387 0.379 0.008 4.67e-01 0.353 0.395 -0.041 7.81e-02
Height21 lassosum.10FCVal LDpred2.Inf 0.435 0.379 0.056 2.98e-11 0.425 0.395 0.030 6.61e-02
Height21 PRScs.PseudoVal LDpred2.Inf 0.436 0.379 0.057 3.36e-17 0.435 0.395 0.040 2.52e-03
Height21 DBSLMM.PseudoVal LDpred2.Inf 0.417 0.379 0.038 1.96e-09 0.428 0.395 0.034 8.97e-03
Height21 LDpred1.10FCVal LDpred2.Inf 0.380 0.379 0.001 8.49e-01 0.383 0.395 -0.012 3.15e-01
Height21 LDpred2.Inf LDpred2.Inf 0.379 0.379 0.000 1.00e+00 0.395 0.395 0.000 1.00e+00
Height21 lassosum.PseudoVal LDpred2.Inf 0.357 0.379 -0.022 1.00e-01 0.354 0.395 -0.041 1.07e-01
Height21 LDpred2.10FCVal LDpred2.Inf 0.431 0.379 0.053 2.14e-25 0.445 0.395 0.051 2.47e-07
Height21 PRScs.10FCVal PRScs.MultiPRS 0.429 0.435 -0.006 7.45e-01 0.434 0.437 -0.003 5.47e-01
Height21 LDpred1.10FCVal PRScs.MultiPRS 0.380 0.435 -0.055 2.85e-03 0.383 0.437 -0.054 1.84e-04
Height21 lassosum.MultiPRS PRScs.MultiPRS 0.440 0.435 0.005 7.98e-01 0.431 0.437 -0.006 3.51e-01
Height21 LDpred2.MultiPRS PRScs.MultiPRS 0.440 0.435 0.005 7.75e-01 0.432 0.437 -0.005 5.78e-01
Height21 All.MultiPRS PRScs.MultiPRS 0.447 0.435 0.012 1.17e-03 0.443 0.437 0.006 3.71e-01
Height21 PRScs.PseudoVal PRScs.MultiPRS 0.436 0.435 0.000 9.83e-01 0.435 0.437 -0.002 1.88e-01
Height21 LDpred1.MultiPRS PRScs.MultiPRS 0.384 0.435 -0.051 5.49e-03 0.397 0.437 -0.040 1.83e-03
Height21 pT+clump.MultiPRS PRScs.MultiPRS 0.399 0.435 -0.036 4.75e-02 0.389 0.437 -0.048 2.06e-04
Height21 lassosum.10FCVal PRScs.MultiPRS 0.435 0.435 0.000 9.92e-01 0.425 0.437 -0.012 1.15e-01
Height21 SBayesR.PseudoVal PRScs.MultiPRS 0.428 0.435 -0.007 7.14e-01 0.434 0.437 -0.003 7.93e-01
Height21 DBSLMM.PseudoVal PRScs.MultiPRS 0.417 0.435 -0.018 3.13e-01 0.428 0.437 -0.008 3.43e-01
Height21 SBLUP.Inf PRScs.MultiPRS 0.378 0.435 -0.057 1.94e-03 0.387 0.437 -0.050 3.14e-04
Height21 LDpred2.Inf PRScs.MultiPRS 0.379 0.435 -0.056 2.40e-03 0.395 0.437 -0.042 1.35e-03
Height21 pT+clump.10FCVal PRScs.MultiPRS 0.387 0.435 -0.048 1.02e-02 0.353 0.437 -0.084 9.07e-07
Height21 LDpred2.10FCVal PRScs.MultiPRS 0.431 0.435 -0.004 8.40e-01 0.445 0.437 0.008 2.96e-01
Height21 lassosum.PseudoVal PRScs.MultiPRS 0.357 0.435 -0.078 3.06e-05 0.354 0.437 -0.083 4.73e-07
Height21 LDpred2.PseudoVal PRScs.MultiPRS 0.378 0.435 -0.057 2.14e-03 0.394 0.437 -0.043 1.55e-03
Height21 LDpred1.Inf PRScs.MultiPRS 0.378 0.435 -0.057 1.97e-03 0.390 0.437 -0.047 3.01e-04
Height21 PRScs.MultiPRS PRScs.MultiPRS 0.435 0.435 0.000 1.00e+00 0.437 0.437 0.000 1.00e+00
Height21 LDpred2.PseudoVal PRScs.10FCVal 0.378 0.429 -0.051 1.04e-10 0.394 0.434 -0.040 1.04e-02
Height21 PRScs.10FCVal PRScs.10FCVal 0.429 0.429 0.000 1.00e+00 0.434 0.434 0.000 1.00e+00
Height21 LDpred2.MultiPRS PRScs.10FCVal 0.440 0.429 0.011 5.42e-01 0.432 0.434 -0.002 8.22e-01
Height21 pT+clump.MultiPRS PRScs.10FCVal 0.399 0.429 -0.030 9.68e-02 0.389 0.434 -0.045 6.26e-04
Height21 LDpred1.Inf PRScs.10FCVal 0.378 0.429 -0.051 1.03e-10 0.390 0.434 -0.044 3.69e-03
Height21 LDpred1.MultiPRS PRScs.10FCVal 0.384 0.429 -0.045 1.38e-02 0.397 0.434 -0.037 1.33e-02
Height21 pT+clump.10FCVal PRScs.10FCVal 0.387 0.429 -0.042 4.48e-07 0.353 0.434 -0.081 9.12e-07
Height21 lassosum.10FCVal PRScs.10FCVal 0.435 0.429 0.006 1.40e-01 0.425 0.434 -0.009 2.25e-01
Height21 PRScs.PseudoVal PRScs.10FCVal 0.436 0.429 0.006 2.45e-02 0.435 0.434 0.001 9.09e-01
Height21 DBSLMM.PseudoVal PRScs.10FCVal 0.417 0.429 -0.013 2.65e-02 0.428 0.434 -0.006 5.88e-01
Height21 SBLUP.Inf PRScs.10FCVal 0.378 0.429 -0.051 4.23e-10 0.387 0.434 -0.047 3.56e-03
Height21 LDpred2.Inf PRScs.10FCVal 0.379 0.429 -0.050 8.68e-11 0.395 0.434 -0.040 9.54e-03
Height21 lassosum.PseudoVal PRScs.10FCVal 0.357 0.429 -0.072 2.39e-20 0.354 0.434 -0.080 1.34e-07
Height21 LDpred2.10FCVal PRScs.10FCVal 0.431 0.429 0.002 6.60e-01 0.445 0.434 0.011 2.54e-01
Height21 lassosum.MultiPRS PRScs.10FCVal 0.440 0.429 0.011 5.61e-01 0.431 0.434 -0.004 6.32e-01
Height21 LDpred1.10FCVal PRScs.10FCVal 0.380 0.429 -0.049 1.78e-09 0.383 0.434 -0.052 1.73e-03
Height21 All.MultiPRS PRScs.10FCVal 0.447 0.429 0.017 3.34e-01 0.443 0.434 0.009 2.44e-01
Height21 SBayesR.PseudoVal PRScs.10FCVal 0.428 0.429 -0.001 8.87e-01 0.434 0.434 0.000 9.92e-01
Height21 PRScs.MultiPRS PRScs.10FCVal 0.435 0.429 0.006 7.45e-01 0.437 0.434 0.003 5.47e-01
Height21 All.MultiPRS PRScs.PseudoVal 0.447 0.436 0.011 5.35e-01 0.443 0.435 0.008 2.60e-01
Height21 pT+clump.MultiPRS PRScs.PseudoVal 0.399 0.436 -0.037 4.43e-02 0.389 0.435 -0.046 4.73e-04
Height21 LDpred2.PseudoVal PRScs.PseudoVal 0.378 0.436 -0.057 6.26e-17 0.394 0.435 -0.040 2.91e-03
Height21 SBayesR.PseudoVal PRScs.PseudoVal 0.428 0.436 -0.007 2.22e-01 0.434 0.435 -0.001 9.48e-01
Height21 LDpred2.MultiPRS PRScs.PseudoVal 0.440 0.436 0.005 7.92e-01 0.432 0.435 -0.003 7.59e-01
Height21 SBLUP.Inf PRScs.PseudoVal 0.378 0.436 -0.058 5.77e-16 0.387 0.435 -0.048 6.60e-04
Height21 LDpred1.Inf PRScs.PseudoVal 0.378 0.436 -0.058 2.65e-17 0.390 0.435 -0.045 6.45e-04
Height21 PRScs.10FCVal PRScs.PseudoVal 0.429 0.436 -0.006 2.45e-02 0.434 0.435 -0.001 9.09e-01
Height21 LDpred2.Inf PRScs.PseudoVal 0.379 0.436 -0.057 3.36e-17 0.395 0.435 -0.040 2.52e-03
Height21 PRScs.PseudoVal PRScs.PseudoVal 0.436 0.436 0.000 1.00e+00 0.435 0.435 0.000 1.00e+00
Height21 LDpred2.10FCVal PRScs.PseudoVal 0.431 0.436 -0.004 3.49e-01 0.445 0.435 0.011 2.04e-01
Height21 pT+clump.10FCVal PRScs.PseudoVal 0.387 0.436 -0.048 1.95e-08 0.353 0.435 -0.081 1.95e-06
Height21 PRScs.MultiPRS PRScs.PseudoVal 0.435 0.436 0.000 9.83e-01 0.437 0.435 0.002 1.88e-01
Height21 lassosum.10FCVal PRScs.PseudoVal 0.435 0.436 -0.001 8.87e-01 0.425 0.435 -0.010 2.06e-01
Height21 lassosum.PseudoVal PRScs.PseudoVal 0.357 0.436 -0.078 4.38e-19 0.354 0.435 -0.081 1.75e-06
Height21 LDpred1.MultiPRS PRScs.PseudoVal 0.384 0.436 -0.052 4.89e-03 0.397 0.435 -0.038 3.68e-03
Height21 lassosum.MultiPRS PRScs.PseudoVal 0.440 0.436 0.004 8.16e-01 0.431 0.435 -0.004 5.60e-01
Height21 LDpred1.10FCVal PRScs.PseudoVal 0.380 0.436 -0.056 1.75e-14 0.383 0.435 -0.052 4.02e-04
Height21 DBSLMM.PseudoVal PRScs.PseudoVal 0.417 0.436 -0.019 1.39e-04 0.428 0.435 -0.006 5.00e-01
Height21 All.MultiPRS pT+clump.MultiPRS 0.447 0.399 0.048 8.50e-03 0.443 0.389 0.054 7.39e-06
Height21 SBayesR.PseudoVal pT+clump.MultiPRS 0.428 0.399 0.030 1.07e-01 0.434 0.389 0.045 1.73e-03
Height21 LDpred1.MultiPRS pT+clump.MultiPRS 0.384 0.399 -0.015 4.29e-01 0.397 0.389 0.008 6.69e-01
Height21 pT+clump.MultiPRS pT+clump.MultiPRS 0.399 0.399 0.000 1.00e+00 0.389 0.389 0.000 1.00e+00
Height21 lassosum.10FCVal pT+clump.MultiPRS 0.435 0.399 0.036 4.78e-02 0.425 0.389 0.036 6.07e-03
Height21 PRScs.10FCVal pT+clump.MultiPRS 0.429 0.399 0.030 9.68e-02 0.434 0.389 0.045 6.26e-04
Height21 DBSLMM.PseudoVal pT+clump.MultiPRS 0.417 0.399 0.018 3.30e-01 0.428 0.389 0.040 3.94e-03
Height21 SBLUP.Inf pT+clump.MultiPRS 0.378 0.399 -0.021 2.62e-01 0.387 0.389 -0.002 9.30e-01
Height21 LDpred2.Inf pT+clump.MultiPRS 0.379 0.399 -0.020 2.88e-01 0.395 0.389 0.006 7.61e-01
Height21 pT+clump.10FCVal pT+clump.MultiPRS 0.387 0.399 -0.011 5.39e-01 0.353 0.389 -0.036 4.81e-05
Height21 LDpred2.10FCVal pT+clump.MultiPRS 0.431 0.399 0.033 7.43e-02 0.445 0.389 0.057 1.04e-04
Height21 PRScs.PseudoVal pT+clump.MultiPRS 0.436 0.399 0.037 4.43e-02 0.435 0.389 0.046 4.73e-04
Height21 LDpred1.10FCVal pT+clump.MultiPRS 0.380 0.399 -0.019 3.16e-01 0.383 0.389 -0.006 7.48e-01
Height21 LDpred1.Inf pT+clump.MultiPRS 0.378 0.399 -0.021 2.63e-01 0.390 0.389 0.001 9.56e-01
Height21 PRScs.MultiPRS pT+clump.MultiPRS 0.435 0.399 0.036 4.75e-02 0.437 0.389 0.048 2.06e-04
Height21 lassosum.PseudoVal pT+clump.MultiPRS 0.357 0.399 -0.041 2.80e-02 0.354 0.389 -0.035 7.68e-02
Height21 LDpred2.PseudoVal pT+clump.MultiPRS 0.378 0.399 -0.020 2.73e-01 0.394 0.389 0.005 7.70e-01
Height21 lassosum.MultiPRS pT+clump.MultiPRS 0.440 0.399 0.041 2.69e-02 0.431 0.389 0.042 1.31e-03
Height21 LDpred2.MultiPRS pT+clump.MultiPRS 0.440 0.399 0.042 2.41e-02 0.432 0.389 0.043 3.36e-03
Height21 LDpred2.10FCVal pT+clump.10FCVal 0.431 0.387 0.044 3.65e-06 0.445 0.353 0.092 1.17e-06
Height21 pT+clump.MultiPRS pT+clump.10FCVal 0.399 0.387 0.011 5.39e-01 0.389 0.353 0.036 4.81e-05
Height21 LDpred2.Inf pT+clump.10FCVal 0.379 0.387 -0.008 4.67e-01 0.395 0.353 0.041 7.81e-02
Height21 SBayesR.PseudoVal pT+clump.10FCVal 0.428 0.387 0.041 7.18e-07 0.434 0.353 0.081 6.75e-07
Height21 PRScs.MultiPRS pT+clump.10FCVal 0.435 0.387 0.048 1.02e-02 0.437 0.353 0.084 9.07e-07
Height21 SBLUP.Inf pT+clump.10FCVal 0.378 0.387 -0.010 4.21e-01 0.387 0.353 0.034 1.61e-01
Height21 lassosum.MultiPRS pT+clump.10FCVal 0.440 0.387 0.052 4.46e-03 0.431 0.353 0.077 2.15e-06
Height21 PRScs.10FCVal pT+clump.10FCVal 0.429 0.387 0.042 4.48e-07 0.434 0.353 0.081 9.12e-07
Height21 LDpred2.MultiPRS pT+clump.10FCVal 0.440 0.387 0.053 3.99e-03 0.432 0.353 0.079 1.04e-05
Height21 lassosum.PseudoVal pT+clump.10FCVal 0.357 0.387 -0.030 4.48e-03 0.354 0.353 0.000 9.86e-01
Height21 LDpred2.PseudoVal pT+clump.10FCVal 0.378 0.387 -0.009 4.38e-01 0.394 0.353 0.041 8.21e-02
Height21 LDpred1.MultiPRS pT+clump.10FCVal 0.384 0.387 -0.003 8.59e-01 0.397 0.353 0.043 6.22e-02
Height21 pT+clump.10FCVal pT+clump.10FCVal 0.387 0.387 0.000 1.00e+00 0.353 0.353 0.000 1.00e+00
Height21 All.MultiPRS pT+clump.10FCVal 0.447 0.387 0.059 1.38e-03 0.443 0.353 0.089 1.34e-09
Height21 LDpred1.Inf pT+clump.10FCVal 0.378 0.387 -0.009 4.14e-01 0.390 0.353 0.036 1.15e-01
Height21 DBSLMM.PseudoVal pT+clump.10FCVal 0.417 0.387 0.029 1.69e-03 0.428 0.353 0.075 5.64e-05
Height21 LDpred1.10FCVal pT+clump.10FCVal 0.380 0.387 -0.007 5.35e-01 0.383 0.353 0.029 2.26e-01
Height21 lassosum.10FCVal pT+clump.10FCVal 0.435 0.387 0.048 7.29e-09 0.425 0.353 0.072 8.44e-06
Height21 PRScs.PseudoVal pT+clump.10FCVal 0.436 0.387 0.048 1.95e-08 0.435 0.353 0.081 1.95e-06
Height21 pT+clump.MultiPRS SBayesR.PseudoVal 0.399 0.428 -0.030 1.07e-01 0.389 0.434 -0.045 1.73e-03
Height21 LDpred1.10FCVal SBayesR.PseudoVal 0.380 0.428 -0.048 1.66e-06 0.383 0.434 -0.051 1.04e-02
Height21 PRScs.10FCVal SBayesR.PseudoVal 0.429 0.428 0.001 8.87e-01 0.434 0.434 0.000 9.92e-01
Height21 LDpred2.10FCVal SBayesR.PseudoVal 0.431 0.428 0.003 6.71e-01 0.445 0.434 0.011 4.04e-01
Height21 lassosum.PseudoVal SBayesR.PseudoVal 0.357 0.428 -0.071 1.23e-20 0.354 0.434 -0.080 1.23e-07
Height21 LDpred2.PseudoVal SBayesR.PseudoVal 0.378 0.428 -0.050 7.66e-07 0.394 0.434 -0.040 4.63e-02
Height21 lassosum.MultiPRS SBayesR.PseudoVal 0.440 0.428 0.011 5.35e-01 0.431 0.434 -0.004 7.46e-01
Height21 LDpred2.MultiPRS SBayesR.PseudoVal 0.440 0.428 0.012 5.15e-01 0.432 0.434 -0.002 8.66e-01
Height21 All.MultiPRS SBayesR.PseudoVal 0.447 0.428 0.018 3.14e-01 0.443 0.434 0.009 3.23e-01
Height21 PRScs.PseudoVal SBayesR.PseudoVal 0.436 0.428 0.007 2.22e-01 0.435 0.434 0.001 9.48e-01
Height21 LDpred1.MultiPRS SBayesR.PseudoVal 0.384 0.428 -0.045 1.57e-02 0.397 0.434 -0.037 5.29e-02
Height21 pT+clump.10FCVal SBayesR.PseudoVal 0.387 0.428 -0.041 7.18e-07 0.353 0.434 -0.081 6.75e-07
Height21 lassosum.10FCVal SBayesR.PseudoVal 0.435 0.428 0.006 2.47e-01 0.425 0.434 -0.009 4.12e-01
Height21 SBayesR.PseudoVal SBayesR.PseudoVal 0.428 0.428 0.000 1.00e+00 0.434 0.434 0.000 1.00e+00
Height21 DBSLMM.PseudoVal SBayesR.PseudoVal 0.417 0.428 -0.012 1.08e-01 0.428 0.434 -0.006 6.83e-01
Height21 SBLUP.Inf SBayesR.PseudoVal 0.378 0.428 -0.051 1.14e-06 0.387 0.434 -0.047 2.12e-02
Height21 LDpred2.Inf SBayesR.PseudoVal 0.379 0.428 -0.050 8.46e-07 0.395 0.434 -0.040 4.52e-02
Height21 LDpred1.Inf SBayesR.PseudoVal 0.378 0.428 -0.051 7.00e-07 0.390 0.434 -0.044 2.50e-02
Height21 PRScs.MultiPRS SBayesR.PseudoVal 0.435 0.428 0.007 7.14e-01 0.437 0.434 0.003 7.93e-01
Height21 LDpred2.10FCVal SBLUP.Inf 0.431 0.378 0.054 4.70e-18 0.445 0.387 0.058 6.59e-07
Height21 PRScs.PseudoVal SBLUP.Inf 0.436 0.378 0.058 5.77e-16 0.435 0.387 0.048 6.60e-04
Height21 LDpred1.10FCVal SBLUP.Inf 0.380 0.378 0.002 6.70e-01 0.383 0.387 -0.005 6.67e-01
Height21 LDpred2.Inf SBLUP.Inf 0.379 0.378 0.001 7.48e-01 0.395 0.387 0.007 3.05e-01
Height21 SBayesR.PseudoVal SBLUP.Inf 0.428 0.378 0.051 1.14e-06 0.434 0.387 0.047 2.12e-02
Height21 lassosum.PseudoVal SBLUP.Inf 0.357 0.378 -0.020 1.32e-01 0.354 0.387 -0.033 2.01e-01
Height21 pT+clump.MultiPRS SBLUP.Inf 0.399 0.378 0.021 2.62e-01 0.389 0.387 0.002 9.30e-01
Height21 lassosum.MultiPRS SBLUP.Inf 0.440 0.378 0.062 8.41e-04 0.431 0.387 0.043 5.74e-03
Height21 PRScs.10FCVal SBLUP.Inf 0.429 0.378 0.051 4.23e-10 0.434 0.387 0.047 3.56e-03
Height21 PRScs.MultiPRS SBLUP.Inf 0.435 0.378 0.057 1.94e-03 0.437 0.387 0.050 3.14e-04
Height21 LDpred1.MultiPRS SBLUP.Inf 0.384 0.378 0.006 7.42e-01 0.397 0.387 0.009 2.18e-01
Height21 LDpred2.PseudoVal SBLUP.Inf 0.378 0.378 0.001 8.87e-01 0.394 0.387 0.007 3.14e-01
Height21 LDpred1.Inf SBLUP.Inf 0.378 0.378 0.000 9.82e-01 0.390 0.387 0.003 6.93e-01
Height21 LDpred2.MultiPRS SBLUP.Inf 0.440 0.378 0.063 7.43e-04 0.432 0.387 0.045 4.87e-03
Height21 All.MultiPRS SBLUP.Inf 0.447 0.378 0.069 1.82e-04 0.443 0.387 0.056 2.84e-04
Height21 SBLUP.Inf SBLUP.Inf 0.378 0.378 0.000 1.00e+00 0.387 0.387 0.000 1.00e+00
Height21 DBSLMM.PseudoVal SBLUP.Inf 0.417 0.378 0.039 3.12e-10 0.428 0.387 0.041 1.27e-03
Height21 pT+clump.10FCVal SBLUP.Inf 0.387 0.378 0.010 4.21e-01 0.353 0.387 -0.034 1.61e-01
Height21 lassosum.10FCVal SBLUP.Inf 0.435 0.378 0.057 1.04e-10 0.425 0.387 0.038 2.97e-02
BMI21 LDpred2.PseudoVal All.MultiPRS 0.333 0.367 -0.034 8.71e-02 0.290 0.327 -0.037 5.91e-03
BMI21 pT+clump.10FCVal All.MultiPRS 0.310 0.367 -0.058 4.03e-03 0.301 0.327 -0.026 1.31e-01
BMI21 LDpred2.MultiPRS All.MultiPRS 0.357 0.367 -0.010 6.06e-01 0.308 0.327 -0.019 2.28e-02
BMI21 PRScs.PseudoVal All.MultiPRS 0.347 0.367 -0.020 3.19e-01 0.302 0.327 -0.025 1.47e-02
BMI21 LDpred1.Inf All.MultiPRS 0.345 0.367 -0.022 2.62e-01 0.298 0.327 -0.029 3.19e-02
BMI21 PRScs.MultiPRS All.MultiPRS 0.354 0.367 -0.013 3.62e-03 0.325 0.327 -0.002 8.02e-01
BMI21 LDpred2.Inf All.MultiPRS 0.333 0.367 -0.034 9.06e-02 0.290 0.327 -0.037 5.37e-03
BMI21 lassosum.PseudoVal All.MultiPRS 0.288 0.367 -0.079 7.24e-05 0.231 0.327 -0.097 1.81e-06
BMI21 LDpred2.10FCVal All.MultiPRS 0.360 0.367 -0.007 7.06e-01 0.315 0.327 -0.012 1.82e-01
BMI21 lassosum.MultiPRS All.MultiPRS 0.361 0.367 -0.007 7.41e-01 0.334 0.327 0.007 3.74e-01
BMI21 LDpred1.10FCVal All.MultiPRS 0.336 0.367 -0.031 1.18e-01 0.306 0.327 -0.021 1.32e-01
BMI21 All.MultiPRS All.MultiPRS 0.367 0.367 0.000 1.00e+00 0.327 0.327 0.000 1.00e+00
BMI21 SBayesR.PseudoVal All.MultiPRS 0.339 0.367 -0.028 1.53e-01 0.290 0.327 -0.037 9.43e-03
BMI21 LDpred1.MultiPRS All.MultiPRS 0.349 0.367 -0.018 1.08e-03 0.306 0.327 -0.021 7.29e-02
BMI21 pT+clump.MultiPRS All.MultiPRS 0.317 0.367 -0.050 1.18e-02 0.295 0.327 -0.032 4.17e-02
BMI21 lassosum.10FCVal All.MultiPRS 0.352 0.367 -0.015 4.45e-01 0.332 0.327 0.005 6.52e-01
BMI21 PRScs.10FCVal All.MultiPRS 0.353 0.367 -0.015 4.61e-01 0.326 0.327 -0.001 9.27e-01
BMI21 DBSLMM.PseudoVal All.MultiPRS 0.354 0.367 -0.013 5.01e-01 0.303 0.327 -0.024 2.60e-02
BMI21 SBLUP.Inf All.MultiPRS 0.324 0.367 -0.043 3.29e-02 0.299 0.327 -0.028 5.84e-02
BMI21 SBayesR.PseudoVal DBSLMM.PseudoVal 0.339 0.354 -0.015 4.11e-02 0.290 0.303 -0.013 4.21e-01
BMI21 LDpred2.Inf DBSLMM.PseudoVal 0.333 0.354 -0.020 3.21e-03 0.290 0.303 -0.012 3.92e-01
BMI21 pT+clump.10FCVal DBSLMM.PseudoVal 0.310 0.354 -0.044 1.47e-07 0.301 0.303 -0.002 9.11e-01
BMI21 PRScs.10FCVal DBSLMM.PseudoVal 0.353 0.354 -0.001 7.81e-01 0.326 0.303 0.023 1.24e-02
BMI21 PRScs.PseudoVal DBSLMM.PseudoVal 0.347 0.354 -0.006 2.26e-01 0.302 0.303 -0.001 9.29e-01
BMI21 pT+clump.MultiPRS DBSLMM.PseudoVal 0.317 0.354 -0.037 6.51e-02 0.295 0.303 -0.008 5.93e-01
BMI21 LDpred1.Inf DBSLMM.PseudoVal 0.345 0.354 -0.009 1.60e-01 0.298 0.303 -0.005 7.11e-01
BMI21 lassosum.MultiPRS DBSLMM.PseudoVal 0.361 0.354 0.007 7.34e-01 0.334 0.303 0.031 6.77e-03
BMI21 LDpred2.10FCVal DBSLMM.PseudoVal 0.360 0.354 0.006 3.34e-01 0.315 0.303 0.012 3.36e-01
BMI21 lassosum.PseudoVal DBSLMM.PseudoVal 0.288 0.354 -0.066 2.85e-11 0.231 0.303 -0.072 6.61e-04
BMI21 LDpred1.10FCVal DBSLMM.PseudoVal 0.336 0.354 -0.018 1.45e-02 0.306 0.303 0.003 8.44e-01
BMI21 LDpred1.MultiPRS DBSLMM.PseudoVal 0.349 0.354 -0.005 8.06e-01 0.306 0.303 0.003 8.11e-01
BMI21 PRScs.MultiPRS DBSLMM.PseudoVal 0.354 0.354 0.000 9.81e-01 0.325 0.303 0.022 1.07e-02
BMI21 All.MultiPRS DBSLMM.PseudoVal 0.367 0.354 0.013 5.01e-01 0.327 0.303 0.024 2.60e-02
BMI21 LDpred2.PseudoVal DBSLMM.PseudoVal 0.333 0.354 -0.021 2.91e-03 0.290 0.303 -0.012 4.00e-01
BMI21 DBSLMM.PseudoVal DBSLMM.PseudoVal 0.354 0.354 0.000 1.00e+00 0.303 0.303 0.000 1.00e+00
BMI21 LDpred2.MultiPRS DBSLMM.PseudoVal 0.357 0.354 0.003 8.76e-01 0.308 0.303 0.006 6.70e-01
BMI21 lassosum.10FCVal DBSLMM.PseudoVal 0.352 0.354 -0.002 7.61e-01 0.332 0.303 0.029 1.45e-02
BMI21 SBLUP.Inf DBSLMM.PseudoVal 0.324 0.354 -0.029 4.67e-05 0.299 0.303 -0.004 7.86e-01
BMI21 SBayesR.PseudoVal lassosum.MultiPRS 0.339 0.361 -0.022 2.82e-01 0.290 0.334 -0.044 2.88e-03
BMI21 LDpred2.10FCVal lassosum.MultiPRS 0.360 0.361 -0.001 9.64e-01 0.315 0.334 -0.019 1.03e-01
BMI21 LDpred1.10FCVal lassosum.MultiPRS 0.336 0.361 -0.025 2.19e-01 0.306 0.334 -0.028 7.60e-02
BMI21 LDpred2.Inf lassosum.MultiPRS 0.333 0.361 -0.027 1.75e-01 0.290 0.334 -0.044 5.08e-03
BMI21 PRScs.10FCVal lassosum.MultiPRS 0.353 0.361 -0.008 6.87e-01 0.326 0.334 -0.008 4.38e-01
BMI21 PRScs.MultiPRS lassosum.MultiPRS 0.354 0.361 -0.006 7.50e-01 0.325 0.334 -0.009 2.88e-01
BMI21 pT+clump.MultiPRS lassosum.MultiPRS 0.317 0.361 -0.044 2.92e-02 0.295 0.334 -0.039 1.69e-02
BMI21 lassosum.MultiPRS lassosum.MultiPRS 0.361 0.361 0.000 1.00e+00 0.334 0.334 0.000 1.00e+00
BMI21 lassosum.10FCVal lassosum.MultiPRS 0.352 0.361 -0.008 6.69e-01 0.332 0.334 -0.002 7.62e-01
BMI21 LDpred2.MultiPRS lassosum.MultiPRS 0.357 0.361 -0.004 5.42e-01 0.308 0.334 -0.026 3.80e-02
BMI21 LDpred1.MultiPRS lassosum.MultiPRS 0.349 0.361 -0.012 5.57e-01 0.306 0.334 -0.028 4.80e-02
BMI21 LDpred2.PseudoVal lassosum.MultiPRS 0.333 0.361 -0.028 1.69e-01 0.290 0.334 -0.044 5.66e-03
BMI21 LDpred1.Inf lassosum.MultiPRS 0.345 0.361 -0.016 4.31e-01 0.298 0.334 -0.037 1.87e-02
BMI21 pT+clump.10FCVal lassosum.MultiPRS 0.310 0.361 -0.051 1.16e-02 0.301 0.334 -0.033 6.72e-02
BMI21 lassosum.PseudoVal lassosum.MultiPRS 0.288 0.361 -0.072 3.70e-04 0.231 0.334 -0.104 4.58e-08
BMI21 SBLUP.Inf lassosum.MultiPRS 0.324 0.361 -0.036 7.19e-02 0.299 0.334 -0.035 2.83e-02
BMI21 DBSLMM.PseudoVal lassosum.MultiPRS 0.354 0.361 -0.007 7.34e-01 0.303 0.334 -0.031 6.77e-03
BMI21 All.MultiPRS lassosum.MultiPRS 0.367 0.361 0.007 7.41e-01 0.327 0.334 -0.007 3.74e-01
BMI21 PRScs.PseudoVal lassosum.MultiPRS 0.347 0.361 -0.013 5.11e-01 0.302 0.334 -0.032 1.34e-03
BMI21 LDpred1.Inf lassosum.10FCVal 0.345 0.352 -0.007 3.03e-01 0.298 0.332 -0.034 2.41e-02
BMI21 PRScs.10FCVal lassosum.10FCVal 0.353 0.352 0.000 9.26e-01 0.326 0.332 -0.006 5.68e-01
BMI21 LDpred2.MultiPRS lassosum.10FCVal 0.357 0.352 0.005 8.08e-01 0.308 0.332 -0.024 6.71e-02
BMI21 lassosum.10FCVal lassosum.10FCVal 0.352 0.352 0.000 1.00e+00 0.332 0.332 0.000 1.00e+00
BMI21 PRScs.PseudoVal lassosum.10FCVal 0.347 0.352 -0.005 3.71e-01 0.302 0.332 -0.030 6.84e-03
BMI21 DBSLMM.PseudoVal lassosum.10FCVal 0.354 0.352 0.002 7.61e-01 0.303 0.332 -0.029 1.45e-02
BMI21 SBLUP.Inf lassosum.10FCVal 0.324 0.352 -0.028 5.02e-04 0.299 0.332 -0.033 3.58e-02
BMI21 LDpred2.Inf lassosum.10FCVal 0.333 0.352 -0.019 1.35e-02 0.290 0.332 -0.042 8.22e-03
BMI21 pT+clump.10FCVal lassosum.10FCVal 0.310 0.352 -0.043 7.13e-07 0.301 0.332 -0.031 6.73e-02
BMI21 LDpred2.10FCVal lassosum.10FCVal 0.360 0.352 0.008 1.94e-01 0.315 0.332 -0.017 1.63e-01
BMI21 lassosum.MultiPRS lassosum.10FCVal 0.361 0.352 0.008 6.69e-01 0.334 0.332 0.002 7.62e-01
BMI21 LDpred1.10FCVal lassosum.10FCVal 0.336 0.352 -0.016 3.88e-02 0.306 0.332 -0.026 9.96e-02
BMI21 All.MultiPRS lassosum.10FCVal 0.367 0.352 0.015 4.45e-01 0.327 0.332 -0.005 6.52e-01
BMI21 SBayesR.PseudoVal lassosum.10FCVal 0.339 0.352 -0.013 8.95e-02 0.290 0.332 -0.042 8.78e-03
BMI21 lassosum.PseudoVal lassosum.10FCVal 0.288 0.352 -0.064 1.20e-11 0.231 0.332 -0.101 3.46e-07
BMI21 pT+clump.MultiPRS lassosum.10FCVal 0.317 0.352 -0.035 7.82e-02 0.295 0.332 -0.037 1.70e-02
BMI21 LDpred2.PseudoVal lassosum.10FCVal 0.333 0.352 -0.019 1.25e-02 0.290 0.332 -0.041 8.97e-03
BMI21 LDpred1.MultiPRS lassosum.10FCVal 0.349 0.352 -0.003 8.73e-01 0.306 0.332 -0.026 6.36e-02
BMI21 PRScs.MultiPRS lassosum.10FCVal 0.354 0.352 0.002 9.11e-01 0.325 0.332 -0.007 4.37e-01
BMI21 lassosum.PseudoVal lassosum.PseudoVal 0.288 0.288 0.000 1.00e+00 0.231 0.231 0.000 1.00e+00
BMI21 pT+clump.MultiPRS lassosum.PseudoVal 0.317 0.288 0.029 1.59e-01 0.295 0.231 0.064 2.82e-03
BMI21 LDpred2.Inf lassosum.PseudoVal 0.333 0.288 0.045 2.80e-04 0.290 0.231 0.060 2.26e-02
BMI21 SBayesR.PseudoVal lassosum.PseudoVal 0.339 0.288 0.051 8.27e-14 0.290 0.231 0.060 2.43e-05
BMI21 PRScs.MultiPRS lassosum.PseudoVal 0.354 0.288 0.066 9.55e-04 0.325 0.231 0.094 6.03e-07
BMI21 SBLUP.Inf lassosum.PseudoVal 0.324 0.288 0.036 4.71e-03 0.299 0.231 0.068 1.07e-02
BMI21 lassosum.MultiPRS lassosum.PseudoVal 0.361 0.288 0.072 3.70e-04 0.334 0.231 0.104 4.58e-08
BMI21 PRScs.10FCVal lassosum.PseudoVal 0.353 0.288 0.064 2.54e-09 0.326 0.231 0.096 2.09e-05
BMI21 LDpred2.MultiPRS lassosum.PseudoVal 0.357 0.288 0.069 7.14e-04 0.308 0.231 0.078 3.54e-04
BMI21 PRScs.PseudoVal lassosum.PseudoVal 0.347 0.288 0.059 5.06e-15 0.302 0.231 0.071 4.61e-06
BMI21 LDpred2.PseudoVal lassosum.PseudoVal 0.333 0.288 0.045 3.51e-04 0.290 0.231 0.060 2.39e-02
BMI21 LDpred1.MultiPRS lassosum.PseudoVal 0.349 0.288 0.061 2.49e-03 0.306 0.231 0.075 2.83e-03
BMI21 pT+clump.10FCVal lassosum.PseudoVal 0.310 0.288 0.021 9.90e-02 0.301 0.231 0.070 7.45e-03
BMI21 All.MultiPRS lassosum.PseudoVal 0.367 0.288 0.079 7.24e-05 0.327 0.231 0.097 1.81e-06
BMI21 LDpred1.Inf lassosum.PseudoVal 0.345 0.288 0.057 3.52e-06 0.298 0.231 0.067 1.01e-02
BMI21 DBSLMM.PseudoVal lassosum.PseudoVal 0.354 0.288 0.066 2.85e-11 0.303 0.231 0.072 6.61e-04
BMI21 LDpred1.10FCVal lassosum.PseudoVal 0.336 0.288 0.048 2.04e-04 0.306 0.231 0.075 4.87e-03
BMI21 lassosum.10FCVal lassosum.PseudoVal 0.352 0.288 0.064 1.20e-11 0.332 0.231 0.101 3.46e-07
BMI21 LDpred2.10FCVal lassosum.PseudoVal 0.360 0.288 0.071 3.43e-12 0.315 0.231 0.084 8.12e-05
BMI21 LDpred2.10FCVal LDpred1.MultiPRS 0.360 0.349 0.011 5.89e-01 0.315 0.306 0.009 4.45e-01
BMI21 PRScs.PseudoVal LDpred1.MultiPRS 0.347 0.349 -0.001 9.41e-01 0.302 0.306 -0.004 7.70e-01
BMI21 LDpred2.Inf LDpred1.MultiPRS 0.333 0.349 -0.016 4.38e-01 0.290 0.306 -0.015 1.15e-01
BMI21 pT+clump.10FCVal LDpred1.MultiPRS 0.310 0.349 -0.039 5.12e-02 0.301 0.306 -0.005 7.60e-01
BMI21 SBayesR.PseudoVal LDpred1.MultiPRS 0.339 0.349 -0.010 6.16e-01 0.290 0.306 -0.016 4.24e-01
BMI21 All.MultiPRS LDpred1.MultiPRS 0.367 0.349 0.018 1.08e-03 0.327 0.306 0.021 7.29e-02
BMI21 LDpred1.10FCVal LDpred1.MultiPRS 0.336 0.349 -0.013 5.18e-01 0.306 0.306 0.000 9.87e-01
BMI21 LDpred1.MultiPRS LDpred1.MultiPRS 0.349 0.349 0.000 1.00e+00 0.306 0.306 0.000 1.00e+00
BMI21 PRScs.10FCVal LDpred1.MultiPRS 0.353 0.349 0.004 8.55e-01 0.326 0.306 0.020 2.37e-02
BMI21 lassosum.10FCVal LDpred1.MultiPRS 0.352 0.349 0.003 8.73e-01 0.332 0.306 0.026 6.36e-02
BMI21 pT+clump.MultiPRS LDpred1.MultiPRS 0.317 0.349 -0.032 1.11e-01 0.295 0.306 -0.011 5.08e-01
BMI21 LDpred1.Inf LDpred1.MultiPRS 0.345 0.349 -0.004 8.37e-01 0.298 0.306 -0.008 2.15e-01
BMI21 lassosum.MultiPRS LDpred1.MultiPRS 0.361 0.349 0.012 5.57e-01 0.334 0.306 0.028 4.80e-02
BMI21 PRScs.MultiPRS LDpred1.MultiPRS 0.354 0.349 0.005 2.81e-01 0.325 0.306 0.019 7.04e-02
BMI21 lassosum.PseudoVal LDpred1.MultiPRS 0.288 0.349 -0.061 2.49e-03 0.231 0.306 -0.075 2.83e-03
BMI21 LDpred2.PseudoVal LDpred1.MultiPRS 0.333 0.349 -0.016 4.27e-01 0.290 0.306 -0.015 1.26e-01
BMI21 DBSLMM.PseudoVal LDpred1.MultiPRS 0.354 0.349 0.005 8.06e-01 0.303 0.306 -0.003 8.11e-01
BMI21 LDpred2.MultiPRS LDpred1.MultiPRS 0.357 0.349 0.008 6.86e-01 0.308 0.306 0.002 8.44e-01
BMI21 SBLUP.Inf LDpred1.MultiPRS 0.324 0.349 -0.024 2.25e-01 0.299 0.306 -0.007 5.15e-01
BMI21 All.MultiPRS LDpred1.Inf 0.367 0.345 0.022 2.62e-01 0.327 0.298 0.029 3.19e-02
BMI21 LDpred2.PseudoVal LDpred1.Inf 0.333 0.345 -0.012 8.81e-03 0.290 0.298 -0.007 4.35e-01
BMI21 SBayesR.PseudoVal LDpred1.Inf 0.339 0.345 -0.006 5.43e-01 0.290 0.298 -0.008 7.13e-01
BMI21 LDpred2.MultiPRS LDpred1.Inf 0.357 0.345 0.012 5.44e-01 0.308 0.298 0.011 4.23e-01
BMI21 PRScs.PseudoVal LDpred1.Inf 0.347 0.345 0.003 7.00e-01 0.302 0.298 0.004 7.88e-01
BMI21 LDpred1.Inf LDpred1.Inf 0.345 0.345 0.000 1.00e+00 0.298 0.298 0.000 1.00e+00
BMI21 pT+clump.10FCVal LDpred1.Inf 0.310 0.345 -0.035 5.93e-06 0.301 0.298 0.003 8.46e-01
BMI21 PRScs.MultiPRS LDpred1.Inf 0.354 0.345 0.009 6.34e-01 0.325 0.298 0.027 1.52e-02
BMI21 lassosum.10FCVal LDpred1.Inf 0.352 0.345 0.007 3.03e-01 0.332 0.298 0.034 2.41e-02
BMI21 pT+clump.MultiPRS LDpred1.Inf 0.317 0.345 -0.028 1.65e-01 0.295 0.298 -0.003 8.62e-01
BMI21 LDpred1.MultiPRS LDpred1.Inf 0.349 0.345 0.004 8.37e-01 0.306 0.298 0.008 2.15e-01
BMI21 PRScs.10FCVal LDpred1.Inf 0.353 0.345 0.008 6.80e-02 0.326 0.298 0.029 2.21e-03
BMI21 LDpred2.Inf LDpred1.Inf 0.333 0.345 -0.011 8.70e-03 0.290 0.298 -0.007 4.11e-01
BMI21 SBLUP.Inf LDpred1.Inf 0.324 0.345 -0.020 7.45e-05 0.299 0.298 0.001 9.26e-01
BMI21 DBSLMM.PseudoVal LDpred1.Inf 0.354 0.345 0.009 1.60e-01 0.303 0.298 0.005 7.11e-01
BMI21 lassosum.MultiPRS LDpred1.Inf 0.361 0.345 0.016 4.31e-01 0.334 0.298 0.037 1.87e-02
BMI21 LDpred1.10FCVal LDpred1.Inf 0.336 0.345 -0.009 6.73e-02 0.306 0.298 0.008 4.18e-01
BMI21 lassosum.PseudoVal LDpred1.Inf 0.288 0.345 -0.057 3.52e-06 0.231 0.298 -0.067 1.01e-02
BMI21 LDpred2.10FCVal LDpred1.Inf 0.360 0.345 0.015 1.10e-02 0.315 0.298 0.017 1.70e-01
BMI21 LDpred1.Inf LDpred1.10FCVal 0.345 0.336 0.009 6.73e-02 0.298 0.306 -0.008 4.18e-01
BMI21 PRScs.MultiPRS LDpred1.10FCVal 0.354 0.336 0.018 3.59e-01 0.325 0.306 0.019 1.43e-01
BMI21 LDpred1.10FCVal LDpred1.10FCVal 0.336 0.336 0.000 1.00e+00 0.306 0.306 0.000 1.00e+00
BMI21 All.MultiPRS LDpred1.10FCVal 0.367 0.336 0.031 1.18e-01 0.327 0.306 0.021 1.32e-01
BMI21 SBayesR.PseudoVal LDpred1.10FCVal 0.339 0.336 0.003 7.68e-01 0.290 0.306 -0.016 4.69e-01
BMI21 DBSLMM.PseudoVal LDpred1.10FCVal 0.354 0.336 0.018 1.45e-02 0.303 0.306 -0.003 8.44e-01
BMI21 pT+clump.MultiPRS LDpred1.10FCVal 0.317 0.336 -0.019 3.45e-01 0.295 0.306 -0.011 5.50e-01
BMI21 lassosum.MultiPRS LDpred1.10FCVal 0.361 0.336 0.025 2.19e-01 0.334 0.306 0.028 7.60e-02
BMI21 PRScs.10FCVal LDpred1.10FCVal 0.353 0.336 0.017 2.52e-03 0.326 0.306 0.020 7.77e-02
BMI21 lassosum.PseudoVal LDpred1.10FCVal 0.288 0.336 -0.048 2.04e-04 0.231 0.306 -0.075 4.87e-03
BMI21 SBLUP.Inf LDpred1.10FCVal 0.324 0.336 -0.011 5.10e-02 0.299 0.306 -0.007 5.66e-01
BMI21 LDpred2.PseudoVal LDpred1.10FCVal 0.333 0.336 -0.003 6.12e-01 0.290 0.306 -0.015 2.01e-01
BMI21 pT+clump.10FCVal LDpred1.10FCVal 0.310 0.336 -0.026 2.61e-03 0.301 0.306 -0.005 7.81e-01
BMI21 LDpred2.MultiPRS LDpred1.10FCVal 0.357 0.336 0.021 2.94e-01 0.308 0.306 0.003 8.60e-01
BMI21 PRScs.PseudoVal LDpred1.10FCVal 0.347 0.336 0.012 1.41e-01 0.302 0.306 -0.004 8.06e-01
BMI21 LDpred2.10FCVal LDpred1.10FCVal 0.360 0.336 0.024 5.15e-04 0.315 0.306 0.009 5.20e-01
BMI21 LDpred1.MultiPRS LDpred1.10FCVal 0.349 0.336 0.013 5.18e-01 0.306 0.306 0.000 9.87e-01
BMI21 LDpred2.Inf LDpred1.10FCVal 0.333 0.336 -0.003 6.52e-01 0.290 0.306 -0.015 1.91e-01
BMI21 lassosum.10FCVal LDpred1.10FCVal 0.352 0.336 0.016 3.88e-02 0.332 0.306 0.026 9.96e-02
BMI21 LDpred1.Inf LDpred2.MultiPRS 0.345 0.357 -0.012 5.44e-01 0.298 0.308 -0.011 4.23e-01
BMI21 DBSLMM.PseudoVal LDpred2.MultiPRS 0.354 0.357 -0.003 8.76e-01 0.303 0.308 -0.006 6.70e-01
BMI21 SBLUP.Inf LDpred2.MultiPRS 0.324 0.357 -0.032 1.05e-01 0.299 0.308 -0.010 5.15e-01
BMI21 LDpred2.Inf LDpred2.MultiPRS 0.333 0.357 -0.024 2.39e-01 0.290 0.308 -0.018 7.16e-02
BMI21 pT+clump.10FCVal LDpred2.MultiPRS 0.310 0.357 -0.047 1.90e-02 0.301 0.308 -0.008 6.80e-01
BMI21 LDpred2.10FCVal LDpred2.MultiPRS 0.360 0.357 0.003 8.90e-01 0.315 0.308 0.007 9.99e-02
BMI21 PRScs.PseudoVal LDpred2.MultiPRS 0.347 0.357 -0.009 6.35e-01 0.302 0.308 -0.007 5.78e-01
BMI21 LDpred1.10FCVal LDpred2.MultiPRS 0.336 0.357 -0.021 2.94e-01 0.306 0.308 -0.003 8.60e-01
BMI21 All.MultiPRS LDpred2.MultiPRS 0.367 0.357 0.010 6.06e-01 0.327 0.308 0.019 2.28e-02
BMI21 SBayesR.PseudoVal LDpred2.MultiPRS 0.339 0.357 -0.018 3.72e-01 0.290 0.308 -0.018 2.73e-01
BMI21 lassosum.PseudoVal LDpred2.MultiPRS 0.288 0.357 -0.069 7.14e-04 0.231 0.308 -0.078 3.54e-04
BMI21 pT+clump.MultiPRS LDpred2.MultiPRS 0.317 0.357 -0.040 4.60e-02 0.295 0.308 -0.014 4.22e-01
BMI21 lassosum.MultiPRS LDpred2.MultiPRS 0.361 0.357 0.004 5.42e-01 0.334 0.308 0.026 3.80e-02
BMI21 PRScs.10FCVal LDpred2.MultiPRS 0.353 0.357 -0.004 8.26e-01 0.326 0.308 0.018 1.11e-01
BMI21 PRScs.MultiPRS LDpred2.MultiPRS 0.354 0.357 -0.003 8.94e-01 0.325 0.308 0.017 1.18e-01
BMI21 lassosum.10FCVal LDpred2.MultiPRS 0.352 0.357 -0.005 8.08e-01 0.332 0.308 0.024 6.71e-02
BMI21 LDpred2.PseudoVal LDpred2.MultiPRS 0.333 0.357 -0.024 2.32e-01 0.290 0.308 -0.018 7.38e-02
BMI21 LDpred1.MultiPRS LDpred2.MultiPRS 0.349 0.357 -0.008 6.86e-01 0.306 0.308 -0.002 8.44e-01
BMI21 LDpred2.MultiPRS LDpred2.MultiPRS 0.357 0.357 0.000 1.00e+00 0.308 0.308 0.000 1.00e+00
BMI21 LDpred1.Inf LDpred2.10FCVal 0.345 0.360 -0.015 1.10e-02 0.298 0.315 -0.017 1.70e-01
BMI21 PRScs.MultiPRS LDpred2.10FCVal 0.354 0.360 -0.005 7.86e-01 0.325 0.315 0.010 3.09e-01
BMI21 LDpred2.MultiPRS LDpred2.10FCVal 0.357 0.360 -0.003 8.90e-01 0.308 0.315 -0.007 9.99e-02
BMI21 PRScs.PseudoVal LDpred2.10FCVal 0.347 0.360 -0.012 2.38e-02 0.302 0.315 -0.013 2.43e-01
BMI21 LDpred2.10FCVal LDpred2.10FCVal 0.360 0.360 0.000 1.00e+00 0.315 0.315 0.000 1.00e+00
BMI21 lassosum.MultiPRS LDpred2.10FCVal 0.361 0.360 0.001 9.64e-01 0.334 0.315 0.019 1.03e-01
BMI21 LDpred1.10FCVal LDpred2.10FCVal 0.336 0.360 -0.024 5.15e-04 0.306 0.315 -0.009 5.20e-01
BMI21 All.MultiPRS LDpred2.10FCVal 0.367 0.360 0.007 7.06e-01 0.327 0.315 0.012 1.82e-01
BMI21 SBayesR.PseudoVal LDpred2.10FCVal 0.339 0.360 -0.021 6.89e-03 0.290 0.315 -0.025 1.24e-01
BMI21 DBSLMM.PseudoVal LDpred2.10FCVal 0.354 0.360 -0.006 3.34e-01 0.303 0.315 -0.012 3.36e-01
BMI21 pT+clump.MultiPRS LDpred2.10FCVal 0.317 0.360 -0.043 3.21e-02 0.295 0.315 -0.020 2.28e-01
BMI21 lassosum.10FCVal LDpred2.10FCVal 0.352 0.360 -0.008 1.94e-01 0.332 0.315 0.017 1.63e-01
BMI21 PRScs.10FCVal LDpred2.10FCVal 0.353 0.360 -0.007 1.53e-01 0.326 0.315 0.011 2.81e-01
BMI21 lassosum.PseudoVal LDpred2.10FCVal 0.288 0.360 -0.071 3.43e-12 0.231 0.315 -0.084 8.12e-05
BMI21 SBLUP.Inf LDpred2.10FCVal 0.324 0.360 -0.035 2.96e-07 0.299 0.315 -0.016 2.55e-01
BMI21 LDpred2.PseudoVal LDpred2.10FCVal 0.333 0.360 -0.027 4.85e-10 0.290 0.315 -0.024 7.75e-03
BMI21 pT+clump.10FCVal LDpred2.10FCVal 0.310 0.360 -0.050 1.48e-08 0.301 0.315 -0.014 4.34e-01
BMI21 LDpred2.Inf LDpred2.10FCVal 0.333 0.360 -0.026 7.94e-10 0.290 0.315 -0.024 7.19e-03
BMI21 LDpred1.MultiPRS LDpred2.10FCVal 0.349 0.360 -0.011 5.89e-01 0.306 0.315 -0.009 4.45e-01
BMI21 lassosum.PseudoVal LDpred2.PseudoVal 0.288 0.333 -0.045 3.51e-04 0.231 0.290 -0.060 2.39e-02
BMI21 SBLUP.Inf LDpred2.PseudoVal 0.324 0.333 -0.009 1.34e-01 0.299 0.290 0.008 4.95e-01
BMI21 SBayesR.PseudoVal LDpred2.PseudoVal 0.339 0.333 0.006 5.46e-01 0.290 0.290 0.000 9.84e-01
BMI21 All.MultiPRS LDpred2.PseudoVal 0.367 0.333 0.034 8.71e-02 0.327 0.290 0.037 5.91e-03
BMI21 PRScs.PseudoVal LDpred2.PseudoVal 0.347 0.333 0.014 4.81e-02 0.302 0.290 0.011 4.77e-01
BMI21 lassosum.MultiPRS LDpred2.PseudoVal 0.361 0.333 0.028 1.69e-01 0.334 0.290 0.044 5.66e-03
BMI21 PRScs.MultiPRS LDpred2.PseudoVal 0.354 0.333 0.021 2.86e-01 0.325 0.290 0.034 5.59e-03
BMI21 LDpred2.MultiPRS LDpred2.PseudoVal 0.357 0.333 0.024 2.32e-01 0.308 0.290 0.018 7.38e-02
BMI21 PRScs.10FCVal LDpred2.PseudoVal 0.353 0.333 0.020 1.38e-04 0.326 0.290 0.036 9.62e-04
BMI21 LDpred2.PseudoVal LDpred2.PseudoVal 0.333 0.333 0.000 1.00e+00 0.290 0.290 0.000 1.00e+00
BMI21 pT+clump.MultiPRS LDpred2.PseudoVal 0.317 0.333 -0.016 4.23e-01 0.295 0.290 0.004 8.23e-01
BMI21 pT+clump.10FCVal LDpred2.PseudoVal 0.310 0.333 -0.023 7.25e-03 0.301 0.290 0.010 5.63e-01
BMI21 lassosum.10FCVal LDpred2.PseudoVal 0.352 0.333 0.019 1.25e-02 0.332 0.290 0.041 8.97e-03
BMI21 LDpred1.Inf LDpred2.PseudoVal 0.345 0.333 0.012 8.81e-03 0.298 0.290 0.007 4.35e-01
BMI21 LDpred1.MultiPRS LDpred2.PseudoVal 0.349 0.333 0.016 4.27e-01 0.306 0.290 0.015 1.26e-01
BMI21 LDpred1.10FCVal LDpred2.PseudoVal 0.336 0.333 0.003 6.12e-01 0.306 0.290 0.015 2.01e-01
BMI21 LDpred2.Inf LDpred2.PseudoVal 0.333 0.333 0.000 4.29e-01 0.290 0.290 0.000 9.31e-01
BMI21 LDpred2.10FCVal LDpred2.PseudoVal 0.360 0.333 0.027 4.85e-10 0.315 0.290 0.024 7.75e-03
BMI21 DBSLMM.PseudoVal LDpred2.PseudoVal 0.354 0.333 0.021 2.91e-03 0.303 0.290 0.012 4.00e-01
BMI21 pT+clump.MultiPRS LDpred2.Inf 0.317 0.333 -0.016 4.13e-01 0.295 0.290 0.004 8.17e-01
BMI21 lassosum.MultiPRS LDpred2.Inf 0.361 0.333 0.027 1.75e-01 0.334 0.290 0.044 5.08e-03
BMI21 SBayesR.PseudoVal LDpred2.Inf 0.339 0.333 0.006 5.67e-01 0.290 0.290 0.000 9.87e-01
BMI21 All.MultiPRS LDpred2.Inf 0.367 0.333 0.034 9.06e-02 0.327 0.290 0.037 5.37e-03
BMI21 SBLUP.Inf LDpred2.Inf 0.324 0.333 -0.009 1.13e-01 0.299 0.290 0.008 4.86e-01
BMI21 LDpred2.PseudoVal LDpred2.Inf 0.333 0.333 0.000 4.29e-01 0.290 0.290 0.000 9.31e-01
BMI21 PRScs.MultiPRS LDpred2.Inf 0.354 0.333 0.021 2.95e-01 0.325 0.290 0.034 4.38e-03
BMI21 LDpred2.MultiPRS LDpred2.Inf 0.357 0.333 0.024 2.39e-01 0.308 0.290 0.018 7.16e-02
BMI21 PRScs.10FCVal LDpred2.Inf 0.353 0.333 0.019 1.31e-04 0.326 0.290 0.036 6.81e-04
BMI21 LDpred1.Inf LDpred2.Inf 0.345 0.333 0.011 8.70e-03 0.298 0.290 0.007 4.11e-01
BMI21 LDpred1.MultiPRS LDpred2.Inf 0.349 0.333 0.016 4.38e-01 0.306 0.290 0.015 1.15e-01
BMI21 pT+clump.10FCVal LDpred2.Inf 0.310 0.333 -0.024 5.78e-03 0.301 0.290 0.010 5.55e-01
BMI21 lassosum.10FCVal LDpred2.Inf 0.352 0.333 0.019 1.35e-02 0.332 0.290 0.042 8.22e-03
BMI21 PRScs.PseudoVal LDpred2.Inf 0.347 0.333 0.014 4.88e-02 0.302 0.290 0.011 4.61e-01
BMI21 DBSLMM.PseudoVal LDpred2.Inf 0.354 0.333 0.020 3.21e-03 0.303 0.290 0.012 3.92e-01
BMI21 LDpred1.10FCVal LDpred2.Inf 0.336 0.333 0.003 6.52e-01 0.306 0.290 0.015 1.91e-01
BMI21 LDpred2.Inf LDpred2.Inf 0.333 0.333 0.000 1.00e+00 0.290 0.290 0.000 1.00e+00
BMI21 lassosum.PseudoVal LDpred2.Inf 0.288 0.333 -0.045 2.80e-04 0.231 0.290 -0.060 2.26e-02
BMI21 LDpred2.10FCVal LDpred2.Inf 0.360 0.333 0.026 7.94e-10 0.315 0.290 0.024 7.19e-03
BMI21 PRScs.10FCVal PRScs.MultiPRS 0.353 0.354 -0.002 9.30e-01 0.326 0.325 0.001 7.80e-01
BMI21 LDpred1.10FCVal PRScs.MultiPRS 0.336 0.354 -0.018 3.59e-01 0.306 0.325 -0.019 1.43e-01
BMI21 lassosum.MultiPRS PRScs.MultiPRS 0.361 0.354 0.006 7.50e-01 0.334 0.325 0.009 2.88e-01
BMI21 LDpred2.MultiPRS PRScs.MultiPRS 0.357 0.354 0.003 8.94e-01 0.308 0.325 -0.017 1.18e-01
BMI21 All.MultiPRS PRScs.MultiPRS 0.367 0.354 0.013 3.62e-03 0.327 0.325 0.002 8.02e-01
BMI21 PRScs.PseudoVal PRScs.MultiPRS 0.347 0.354 -0.007 7.29e-01 0.302 0.325 -0.023 2.32e-04
BMI21 LDpred1.MultiPRS PRScs.MultiPRS 0.349 0.354 -0.005 2.81e-01 0.306 0.325 -0.019 7.04e-02
BMI21 pT+clump.MultiPRS PRScs.MultiPRS 0.317 0.354 -0.037 6.11e-02 0.295 0.325 -0.030 3.00e-02
BMI21 lassosum.10FCVal PRScs.MultiPRS 0.352 0.354 -0.002 9.11e-01 0.332 0.325 0.007 4.37e-01
BMI21 SBayesR.PseudoVal PRScs.MultiPRS 0.339 0.354 -0.015 4.39e-01 0.290 0.325 -0.035 1.15e-02
BMI21 DBSLMM.PseudoVal PRScs.MultiPRS 0.354 0.354 0.000 9.81e-01 0.303 0.325 -0.022 1.07e-02
BMI21 SBLUP.Inf PRScs.MultiPRS 0.324 0.354 -0.030 1.37e-01 0.299 0.325 -0.026 4.47e-02
BMI21 LDpred2.Inf PRScs.MultiPRS 0.333 0.354 -0.021 2.95e-01 0.290 0.325 -0.034 4.38e-03
BMI21 pT+clump.10FCVal PRScs.MultiPRS 0.310 0.354 -0.045 2.60e-02 0.301 0.325 -0.024 1.30e-01
BMI21 LDpred2.10FCVal PRScs.MultiPRS 0.360 0.354 0.005 7.86e-01 0.315 0.325 -0.010 3.09e-01
BMI21 lassosum.PseudoVal PRScs.MultiPRS 0.288 0.354 -0.066 9.55e-04 0.231 0.325 -0.094 6.03e-07
BMI21 LDpred2.PseudoVal PRScs.MultiPRS 0.333 0.354 -0.021 2.86e-01 0.290 0.325 -0.034 5.59e-03
BMI21 LDpred1.Inf PRScs.MultiPRS 0.345 0.354 -0.009 6.34e-01 0.298 0.325 -0.027 1.52e-02
BMI21 PRScs.MultiPRS PRScs.MultiPRS 0.354 0.354 0.000 1.00e+00 0.325 0.325 0.000 1.00e+00
BMI21 LDpred2.PseudoVal PRScs.10FCVal 0.333 0.353 -0.020 1.38e-04 0.290 0.326 -0.036 9.62e-04
BMI21 PRScs.10FCVal PRScs.10FCVal 0.353 0.353 0.000 1.00e+00 0.326 0.326 0.000 1.00e+00
BMI21 LDpred2.MultiPRS PRScs.10FCVal 0.357 0.353 0.004 8.26e-01 0.308 0.326 -0.018 1.11e-01
BMI21 pT+clump.MultiPRS PRScs.10FCVal 0.317 0.353 -0.036 7.46e-02 0.295 0.326 -0.032 3.45e-02
BMI21 LDpred1.Inf PRScs.10FCVal 0.345 0.353 -0.008 6.80e-02 0.298 0.326 -0.029 2.21e-03
BMI21 LDpred1.MultiPRS PRScs.10FCVal 0.349 0.353 -0.004 8.55e-01 0.306 0.326 -0.020 2.37e-02
BMI21 pT+clump.10FCVal PRScs.10FCVal 0.310 0.353 -0.043 1.39e-08 0.301 0.326 -0.025 9.91e-02
BMI21 lassosum.10FCVal PRScs.10FCVal 0.352 0.353 0.000 9.26e-01 0.332 0.326 0.006 5.68e-01
BMI21 PRScs.PseudoVal PRScs.10FCVal 0.347 0.353 -0.005 2.81e-01 0.302 0.326 -0.024 1.49e-02
BMI21 DBSLMM.PseudoVal PRScs.10FCVal 0.354 0.353 0.001 7.81e-01 0.303 0.326 -0.023 1.24e-02
BMI21 SBLUP.Inf PRScs.10FCVal 0.324 0.353 -0.028 2.97e-07 0.299 0.326 -0.028 1.85e-02
BMI21 LDpred2.Inf PRScs.10FCVal 0.333 0.353 -0.019 1.31e-04 0.290 0.326 -0.036 6.81e-04
BMI21 lassosum.PseudoVal PRScs.10FCVal 0.288 0.353 -0.064 2.54e-09 0.231 0.326 -0.096 2.09e-05
BMI21 LDpred2.10FCVal PRScs.10FCVal 0.360 0.353 0.007 1.53e-01 0.315 0.326 -0.011 2.81e-01
BMI21 lassosum.MultiPRS PRScs.10FCVal 0.361 0.353 0.008 6.87e-01 0.334 0.326 0.008 4.38e-01
BMI21 LDpred1.10FCVal PRScs.10FCVal 0.336 0.353 -0.017 2.52e-03 0.306 0.326 -0.020 7.77e-02
BMI21 All.MultiPRS PRScs.10FCVal 0.367 0.353 0.015 4.61e-01 0.327 0.326 0.001 9.27e-01
BMI21 SBayesR.PseudoVal PRScs.10FCVal 0.339 0.353 -0.014 9.89e-02 0.290 0.326 -0.036 3.26e-02
BMI21 PRScs.MultiPRS PRScs.10FCVal 0.354 0.353 0.002 9.30e-01 0.325 0.326 -0.001 7.80e-01
BMI21 All.MultiPRS PRScs.PseudoVal 0.367 0.347 0.020 3.19e-01 0.327 0.302 0.025 1.47e-02
BMI21 pT+clump.MultiPRS PRScs.PseudoVal 0.317 0.347 -0.031 1.28e-01 0.295 0.302 -0.007 6.28e-01
BMI21 LDpred2.PseudoVal PRScs.PseudoVal 0.333 0.347 -0.014 4.81e-02 0.290 0.302 -0.011 4.77e-01
BMI21 SBayesR.PseudoVal PRScs.PseudoVal 0.339 0.347 -0.008 1.32e-01 0.290 0.302 -0.012 2.96e-01
BMI21 LDpred2.MultiPRS PRScs.PseudoVal 0.357 0.347 0.009 6.35e-01 0.308 0.302 0.007 5.78e-01
BMI21 SBLUP.Inf PRScs.PseudoVal 0.324 0.347 -0.023 3.36e-03 0.299 0.302 -0.003 8.55e-01
BMI21 LDpred1.Inf PRScs.PseudoVal 0.345 0.347 -0.003 7.00e-01 0.298 0.302 -0.004 7.88e-01
BMI21 PRScs.10FCVal PRScs.PseudoVal 0.353 0.347 0.005 2.81e-01 0.326 0.302 0.024 1.49e-02
BMI21 LDpred2.Inf PRScs.PseudoVal 0.333 0.347 -0.014 4.88e-02 0.290 0.302 -0.011 4.61e-01
BMI21 PRScs.PseudoVal PRScs.PseudoVal 0.347 0.347 0.000 1.00e+00 0.302 0.302 0.000 1.00e+00
BMI21 LDpred2.10FCVal PRScs.PseudoVal 0.360 0.347 0.012 2.38e-02 0.315 0.302 0.013 2.43e-01
BMI21 pT+clump.10FCVal PRScs.PseudoVal 0.310 0.347 -0.038 1.92e-05 0.301 0.302 -0.001 9.62e-01
BMI21 PRScs.MultiPRS PRScs.PseudoVal 0.354 0.347 0.007 7.29e-01 0.325 0.302 0.023 2.32e-04
BMI21 lassosum.10FCVal PRScs.PseudoVal 0.352 0.347 0.005 3.71e-01 0.332 0.302 0.030 6.84e-03
BMI21 lassosum.PseudoVal PRScs.PseudoVal 0.288 0.347 -0.059 5.06e-15 0.231 0.302 -0.071 4.61e-06
BMI21 LDpred1.MultiPRS PRScs.PseudoVal 0.349 0.347 0.001 9.41e-01 0.306 0.302 0.004 7.70e-01
BMI21 lassosum.MultiPRS PRScs.PseudoVal 0.361 0.347 0.013 5.11e-01 0.334 0.302 0.032 1.34e-03
BMI21 LDpred1.10FCVal PRScs.PseudoVal 0.336 0.347 -0.012 1.41e-01 0.306 0.302 0.004 8.06e-01
BMI21 DBSLMM.PseudoVal PRScs.PseudoVal 0.354 0.347 0.006 2.26e-01 0.303 0.302 0.001 9.29e-01
BMI21 All.MultiPRS pT+clump.MultiPRS 0.367 0.317 0.050 1.18e-02 0.327 0.295 0.032 4.17e-02
BMI21 SBayesR.PseudoVal pT+clump.MultiPRS 0.339 0.317 0.022 2.73e-01 0.290 0.295 -0.005 8.01e-01
BMI21 LDpred1.MultiPRS pT+clump.MultiPRS 0.349 0.317 0.032 1.11e-01 0.306 0.295 0.011 5.08e-01
BMI21 pT+clump.MultiPRS pT+clump.MultiPRS 0.317 0.317 0.000 1.00e+00 0.295 0.295 0.000 1.00e+00
BMI21 lassosum.10FCVal pT+clump.MultiPRS 0.352 0.317 0.035 7.82e-02 0.332 0.295 0.037 1.70e-02
BMI21 PRScs.10FCVal pT+clump.MultiPRS 0.353 0.317 0.036 7.46e-02 0.326 0.295 0.032 3.45e-02
BMI21 DBSLMM.PseudoVal pT+clump.MultiPRS 0.354 0.317 0.037 6.51e-02 0.303 0.295 0.008 5.93e-01
BMI21 SBLUP.Inf pT+clump.MultiPRS 0.324 0.317 0.008 7.08e-01 0.299 0.295 0.004 8.29e-01
BMI21 LDpred2.Inf pT+clump.MultiPRS 0.333 0.317 0.016 4.13e-01 0.290 0.295 -0.004 8.17e-01
BMI21 pT+clump.10FCVal pT+clump.MultiPRS 0.310 0.317 -0.007 7.17e-01 0.301 0.295 0.006 4.30e-01
BMI21 LDpred2.10FCVal pT+clump.MultiPRS 0.360 0.317 0.043 3.21e-02 0.315 0.295 0.020 2.28e-01
BMI21 PRScs.PseudoVal pT+clump.MultiPRS 0.347 0.317 0.031 1.28e-01 0.302 0.295 0.007 6.28e-01
BMI21 LDpred1.10FCVal pT+clump.MultiPRS 0.336 0.317 0.019 3.45e-01 0.306 0.295 0.011 5.50e-01
BMI21 LDpred1.Inf pT+clump.MultiPRS 0.345 0.317 0.028 1.65e-01 0.298 0.295 0.003 8.62e-01
BMI21 PRScs.MultiPRS pT+clump.MultiPRS 0.354 0.317 0.037 6.11e-02 0.325 0.295 0.030 3.00e-02
BMI21 lassosum.PseudoVal pT+clump.MultiPRS 0.288 0.317 -0.029 1.59e-01 0.231 0.295 -0.064 2.82e-03
BMI21 LDpred2.PseudoVal pT+clump.MultiPRS 0.333 0.317 0.016 4.23e-01 0.290 0.295 -0.004 8.23e-01
BMI21 lassosum.MultiPRS pT+clump.MultiPRS 0.361 0.317 0.044 2.92e-02 0.334 0.295 0.039 1.69e-02
BMI21 LDpred2.MultiPRS pT+clump.MultiPRS 0.357 0.317 0.040 4.60e-02 0.308 0.295 0.014 4.22e-01
BMI21 LDpred2.10FCVal pT+clump.10FCVal 0.360 0.310 0.050 1.48e-08 0.315 0.301 0.014 4.34e-01
BMI21 pT+clump.MultiPRS pT+clump.10FCVal 0.317 0.310 0.007 7.17e-01 0.295 0.301 -0.006 4.30e-01
BMI21 LDpred2.Inf pT+clump.10FCVal 0.333 0.310 0.024 5.78e-03 0.290 0.301 -0.010 5.55e-01
BMI21 SBayesR.PseudoVal pT+clump.10FCVal 0.339 0.310 0.029 6.51e-03 0.290 0.301 -0.011 6.24e-01
BMI21 PRScs.MultiPRS pT+clump.10FCVal 0.354 0.310 0.045 2.60e-02 0.325 0.301 0.024 1.30e-01
BMI21 SBLUP.Inf pT+clump.10FCVal 0.324 0.310 0.015 8.52e-02 0.299 0.301 -0.002 9.03e-01
BMI21 lassosum.MultiPRS pT+clump.10FCVal 0.361 0.310 0.051 1.16e-02 0.334 0.301 0.033 6.72e-02
BMI21 PRScs.10FCVal pT+clump.10FCVal 0.353 0.310 0.043 1.39e-08 0.326 0.301 0.025 9.91e-02
BMI21 LDpred2.MultiPRS pT+clump.10FCVal 0.357 0.310 0.047 1.90e-02 0.308 0.301 0.008 6.80e-01
BMI21 lassosum.PseudoVal pT+clump.10FCVal 0.288 0.310 -0.021 9.90e-02 0.231 0.301 -0.070 7.45e-03
BMI21 LDpred2.PseudoVal pT+clump.10FCVal 0.333 0.310 0.023 7.25e-03 0.290 0.301 -0.010 5.63e-01
BMI21 LDpred1.MultiPRS pT+clump.10FCVal 0.349 0.310 0.039 5.12e-02 0.306 0.301 0.005 7.60e-01
BMI21 pT+clump.10FCVal pT+clump.10FCVal 0.310 0.310 0.000 1.00e+00 0.301 0.301 0.000 1.00e+00
BMI21 All.MultiPRS pT+clump.10FCVal 0.367 0.310 0.058 4.03e-03 0.327 0.301 0.026 1.31e-01
BMI21 LDpred1.Inf pT+clump.10FCVal 0.345 0.310 0.035 5.93e-06 0.298 0.301 -0.003 8.46e-01
BMI21 DBSLMM.PseudoVal pT+clump.10FCVal 0.354 0.310 0.044 1.47e-07 0.303 0.301 0.002 9.11e-01
BMI21 LDpred1.10FCVal pT+clump.10FCVal 0.336 0.310 0.026 2.61e-03 0.306 0.301 0.005 7.81e-01
BMI21 lassosum.10FCVal pT+clump.10FCVal 0.352 0.310 0.043 7.13e-07 0.332 0.301 0.031 6.73e-02
BMI21 PRScs.PseudoVal pT+clump.10FCVal 0.347 0.310 0.038 1.92e-05 0.302 0.301 0.001 9.62e-01
BMI21 pT+clump.MultiPRS SBayesR.PseudoVal 0.317 0.339 -0.022 2.73e-01 0.295 0.290 0.005 8.01e-01
BMI21 LDpred1.10FCVal SBayesR.PseudoVal 0.336 0.339 -0.003 7.68e-01 0.306 0.290 0.016 4.69e-01
BMI21 PRScs.10FCVal SBayesR.PseudoVal 0.353 0.339 0.014 9.89e-02 0.326 0.290 0.036 3.26e-02
BMI21 LDpred2.10FCVal SBayesR.PseudoVal 0.360 0.339 0.021 6.89e-03 0.315 0.290 0.025 1.24e-01
BMI21 lassosum.PseudoVal SBayesR.PseudoVal 0.288 0.339 -0.051 8.27e-14 0.231 0.290 -0.060 2.43e-05
BMI21 LDpred2.PseudoVal SBayesR.PseudoVal 0.333 0.339 -0.006 5.46e-01 0.290 0.290 0.000 9.84e-01
BMI21 lassosum.MultiPRS SBayesR.PseudoVal 0.361 0.339 0.022 2.82e-01 0.334 0.290 0.044 2.88e-03
BMI21 LDpred2.MultiPRS SBayesR.PseudoVal 0.357 0.339 0.018 3.72e-01 0.308 0.290 0.018 2.73e-01
BMI21 All.MultiPRS SBayesR.PseudoVal 0.367 0.339 0.028 1.53e-01 0.327 0.290 0.037 9.43e-03
BMI21 PRScs.PseudoVal SBayesR.PseudoVal 0.347 0.339 0.008 1.32e-01 0.302 0.290 0.012 2.96e-01
BMI21 LDpred1.MultiPRS SBayesR.PseudoVal 0.349 0.339 0.010 6.16e-01 0.306 0.290 0.016 4.24e-01
BMI21 pT+clump.10FCVal SBayesR.PseudoVal 0.310 0.339 -0.029 6.51e-03 0.301 0.290 0.011 6.24e-01
BMI21 lassosum.10FCVal SBayesR.PseudoVal 0.352 0.339 0.013 8.95e-02 0.332 0.290 0.042 8.78e-03
BMI21 SBayesR.PseudoVal SBayesR.PseudoVal 0.339 0.339 0.000 1.00e+00 0.290 0.290 0.000 1.00e+00
BMI21 DBSLMM.PseudoVal SBayesR.PseudoVal 0.354 0.339 0.015 4.11e-02 0.303 0.290 0.013 4.21e-01
BMI21 SBLUP.Inf SBayesR.PseudoVal 0.324 0.339 -0.015 1.58e-01 0.299 0.290 0.009 6.89e-01
BMI21 LDpred2.Inf SBayesR.PseudoVal 0.333 0.339 -0.006 5.67e-01 0.290 0.290 0.000 9.87e-01
BMI21 LDpred1.Inf SBayesR.PseudoVal 0.345 0.339 0.006 5.43e-01 0.298 0.290 0.008 7.13e-01
BMI21 PRScs.MultiPRS SBayesR.PseudoVal 0.354 0.339 0.015 4.39e-01 0.325 0.290 0.035 1.15e-02
BMI21 LDpred2.10FCVal SBLUP.Inf 0.360 0.324 0.035 2.96e-07 0.315 0.299 0.016 2.55e-01
BMI21 PRScs.PseudoVal SBLUP.Inf 0.347 0.324 0.023 3.36e-03 0.302 0.299 0.003 8.55e-01
BMI21 LDpred1.10FCVal SBLUP.Inf 0.336 0.324 0.011 5.10e-02 0.306 0.299 0.007 5.66e-01
BMI21 LDpred2.Inf SBLUP.Inf 0.333 0.324 0.009 1.13e-01 0.290 0.299 -0.008 4.86e-01
BMI21 SBayesR.PseudoVal SBLUP.Inf 0.339 0.324 0.015 1.58e-01 0.290 0.299 -0.009 6.89e-01
BMI21 lassosum.PseudoVal SBLUP.Inf 0.288 0.324 -0.036 4.71e-03 0.231 0.299 -0.068 1.07e-02
BMI21 pT+clump.MultiPRS SBLUP.Inf 0.317 0.324 -0.008 7.08e-01 0.295 0.299 -0.004 8.29e-01
BMI21 lassosum.MultiPRS SBLUP.Inf 0.361 0.324 0.036 7.19e-02 0.334 0.299 0.035 2.83e-02
BMI21 PRScs.10FCVal SBLUP.Inf 0.353 0.324 0.028 2.97e-07 0.326 0.299 0.028 1.85e-02
BMI21 PRScs.MultiPRS SBLUP.Inf 0.354 0.324 0.030 1.37e-01 0.325 0.299 0.026 4.47e-02
BMI21 LDpred1.MultiPRS SBLUP.Inf 0.349 0.324 0.024 2.25e-01 0.306 0.299 0.007 5.15e-01
BMI21 LDpred2.PseudoVal SBLUP.Inf 0.333 0.324 0.009 1.34e-01 0.290 0.299 -0.008 4.95e-01
BMI21 LDpred1.Inf SBLUP.Inf 0.345 0.324 0.020 7.45e-05 0.298 0.299 -0.001 9.26e-01
BMI21 LDpred2.MultiPRS SBLUP.Inf 0.357 0.324 0.032 1.05e-01 0.308 0.299 0.010 5.15e-01
BMI21 All.MultiPRS SBLUP.Inf 0.367 0.324 0.043 3.29e-02 0.327 0.299 0.028 5.84e-02
BMI21 SBLUP.Inf SBLUP.Inf 0.324 0.324 0.000 1.00e+00 0.299 0.299 0.000 1.00e+00
BMI21 DBSLMM.PseudoVal SBLUP.Inf 0.354 0.324 0.029 4.67e-05 0.303 0.299 0.004 7.86e-01
BMI21 pT+clump.10FCVal SBLUP.Inf 0.310 0.324 -0.015 8.52e-02 0.301 0.299 0.002 9.03e-01
BMI21 lassosum.10FCVal SBLUP.Inf 0.352 0.324 0.028 5.02e-04 0.332 0.299 0.033 3.58e-02
GCSE LDpred2.PseudoVal All.MultiPRS 0.406 0.417 -0.012 4.66e-01 0.332 0.347 -0.014 2.51e-02
GCSE pT+clump.10FCVal All.MultiPRS 0.373 0.417 -0.044 5.86e-03 0.311 0.347 -0.035 3.75e-03
GCSE LDpred2.MultiPRS All.MultiPRS 0.412 0.417 -0.005 1.61e-02 0.339 0.347 -0.008 6.48e-02
GCSE PRScs.PseudoVal All.MultiPRS 0.397 0.417 -0.020 2.11e-01 0.351 0.347 0.005 5.38e-01
GCSE LDpred1.Inf All.MultiPRS 0.408 0.417 -0.010 5.46e-01 0.341 0.347 -0.006 4.01e-01
GCSE PRScs.MultiPRS All.MultiPRS 0.413 0.417 -0.004 7.89e-01 0.346 0.347 -0.001 8.67e-01
GCSE LDpred2.Inf All.MultiPRS 0.405 0.417 -0.012 4.52e-01 0.331 0.347 -0.016 1.59e-02
GCSE lassosum.PseudoVal All.MultiPRS 0.321 0.417 -0.097 4.07e-09 0.276 0.347 -0.071 3.89e-05
GCSE LDpred2.10FCVal All.MultiPRS 0.412 0.417 -0.006 7.17e-01 0.342 0.347 -0.004 3.38e-01
GCSE lassosum.MultiPRS All.MultiPRS 0.411 0.417 -0.006 6.98e-01 0.347 0.347 0.000 9.59e-01
GCSE LDpred1.10FCVal All.MultiPRS 0.402 0.417 -0.015 3.35e-01 0.330 0.347 -0.016 3.81e-02
GCSE All.MultiPRS All.MultiPRS 0.417 0.417 0.000 1.00e+00 0.347 0.347 0.000 1.00e+00
GCSE SBayesR.PseudoVal All.MultiPRS 0.397 0.417 -0.021 1.96e-01 0.331 0.347 -0.016 9.45e-02
GCSE LDpred1.MultiPRS All.MultiPRS 0.409 0.417 -0.008 6.07e-01 0.340 0.347 -0.007 2.45e-01
GCSE pT+clump.MultiPRS All.MultiPRS 0.381 0.417 -0.037 2.16e-02 0.328 0.347 -0.018 7.70e-02
GCSE lassosum.10FCVal All.MultiPRS 0.407 0.417 -0.010 5.29e-01 0.348 0.347 0.001 8.42e-01
GCSE PRScs.10FCVal All.MultiPRS 0.410 0.417 -0.007 6.61e-01 0.341 0.347 -0.006 2.92e-01
GCSE DBSLMM.PseudoVal All.MultiPRS 0.401 0.417 -0.016 3.14e-01 0.337 0.347 -0.010 1.66e-01
GCSE SBLUP.Inf All.MultiPRS 0.400 0.417 -0.018 2.66e-01 0.335 0.347 -0.012 1.47e-01
GCSE SBayesR.PseudoVal DBSLMM.PseudoVal 0.397 0.401 -0.005 3.44e-01 0.331 0.337 -0.006 5.72e-01
GCSE LDpred2.Inf DBSLMM.PseudoVal 0.405 0.401 0.004 3.90e-01 0.331 0.337 -0.006 5.44e-01
GCSE pT+clump.10FCVal DBSLMM.PseudoVal 0.373 0.401 -0.028 2.61e-05 0.311 0.337 -0.026 7.14e-02
GCSE PRScs.10FCVal DBSLMM.PseudoVal 0.410 0.401 0.009 1.71e-02 0.341 0.337 0.004 6.46e-01
GCSE PRScs.PseudoVal DBSLMM.PseudoVal 0.397 0.401 -0.004 3.38e-01 0.351 0.337 0.014 9.88e-02
GCSE pT+clump.MultiPRS DBSLMM.PseudoVal 0.381 0.401 -0.021 2.13e-01 0.328 0.337 -0.009 4.68e-01
GCSE LDpred1.Inf DBSLMM.PseudoVal 0.408 0.401 0.006 1.45e-01 0.341 0.337 0.004 6.60e-01
GCSE lassosum.MultiPRS DBSLMM.PseudoVal 0.411 0.401 0.010 5.35e-01 0.347 0.337 0.010 2.52e-01
GCSE LDpred2.10FCVal DBSLMM.PseudoVal 0.412 0.401 0.010 1.61e-02 0.342 0.337 0.005 5.58e-01
GCSE lassosum.PseudoVal DBSLMM.PseudoVal 0.321 0.401 -0.081 3.95e-22 0.276 0.337 -0.061 6.21e-04
GCSE LDpred1.10FCVal DBSLMM.PseudoVal 0.402 0.401 0.001 8.86e-01 0.330 0.337 -0.006 5.42e-01
GCSE LDpred1.MultiPRS DBSLMM.PseudoVal 0.409 0.401 0.008 6.22e-01 0.340 0.337 0.003 7.50e-01
GCSE PRScs.MultiPRS DBSLMM.PseudoVal 0.413 0.401 0.012 4.59e-01 0.346 0.337 0.009 1.97e-01
GCSE All.MultiPRS DBSLMM.PseudoVal 0.417 0.401 0.016 3.14e-01 0.347 0.337 0.010 1.66e-01
GCSE LDpred2.PseudoVal DBSLMM.PseudoVal 0.406 0.401 0.004 3.40e-01 0.332 0.337 -0.004 6.50e-01
GCSE DBSLMM.PseudoVal DBSLMM.PseudoVal 0.401 0.401 0.000 1.00e+00 0.337 0.337 0.000 1.00e+00
GCSE LDpred2.MultiPRS DBSLMM.PseudoVal 0.412 0.401 0.011 4.79e-01 0.339 0.337 0.002 8.05e-01
GCSE lassosum.10FCVal DBSLMM.PseudoVal 0.407 0.401 0.006 1.61e-01 0.348 0.337 0.011 2.43e-01
GCSE SBLUP.Inf DBSLMM.PseudoVal 0.400 0.401 -0.002 7.40e-01 0.335 0.337 -0.002 8.41e-01
GCSE SBayesR.PseudoVal lassosum.MultiPRS 0.397 0.411 -0.015 3.63e-01 0.331 0.347 -0.016 1.26e-01
GCSE LDpred2.10FCVal lassosum.MultiPRS 0.412 0.411 0.000 9.78e-01 0.342 0.347 -0.005 4.81e-01
GCSE LDpred1.10FCVal lassosum.MultiPRS 0.402 0.411 -0.009 5.66e-01 0.330 0.347 -0.016 8.28e-02
GCSE LDpred2.Inf lassosum.MultiPRS 0.405 0.411 -0.006 7.16e-01 0.331 0.347 -0.016 7.29e-02
GCSE PRScs.10FCVal lassosum.MultiPRS 0.410 0.411 -0.001 9.61e-01 0.341 0.347 -0.006 3.58e-01
GCSE PRScs.MultiPRS lassosum.MultiPRS 0.413 0.411 0.002 4.70e-01 0.346 0.347 -0.001 8.58e-01
GCSE pT+clump.MultiPRS lassosum.MultiPRS 0.381 0.411 -0.030 6.07e-02 0.328 0.347 -0.019 1.13e-01
GCSE lassosum.MultiPRS lassosum.MultiPRS 0.411 0.411 0.000 1.00e+00 0.347 0.347 0.000 1.00e+00
GCSE lassosum.10FCVal lassosum.MultiPRS 0.407 0.411 -0.004 8.11e-01 0.348 0.347 0.001 7.97e-01
GCSE LDpred2.MultiPRS lassosum.MultiPRS 0.412 0.411 0.001 9.29e-01 0.339 0.347 -0.008 2.75e-01
GCSE LDpred1.MultiPRS lassosum.MultiPRS 0.409 0.411 -0.002 6.04e-01 0.340 0.347 -0.007 3.80e-01
GCSE LDpred2.PseudoVal lassosum.MultiPRS 0.406 0.411 -0.005 7.34e-01 0.332 0.347 -0.014 9.52e-02
GCSE LDpred1.Inf lassosum.MultiPRS 0.408 0.411 -0.003 8.32e-01 0.341 0.347 -0.006 4.86e-01
GCSE pT+clump.10FCVal lassosum.MultiPRS 0.373 0.411 -0.038 1.81e-02 0.311 0.347 -0.036 7.92e-03
GCSE lassosum.PseudoVal lassosum.MultiPRS 0.321 0.411 -0.091 3.52e-08 0.276 0.347 -0.071 2.48e-05
GCSE SBLUP.Inf lassosum.MultiPRS 0.400 0.411 -0.012 4.70e-01 0.335 0.347 -0.012 2.25e-01
GCSE DBSLMM.PseudoVal lassosum.MultiPRS 0.401 0.411 -0.010 5.35e-01 0.337 0.347 -0.010 2.52e-01
GCSE All.MultiPRS lassosum.MultiPRS 0.417 0.411 0.006 6.98e-01 0.347 0.347 0.000 9.59e-01
GCSE PRScs.PseudoVal lassosum.MultiPRS 0.397 0.411 -0.014 3.89e-01 0.351 0.347 0.004 5.77e-01
GCSE LDpred1.Inf lassosum.10FCVal 0.408 0.407 0.000 9.14e-01 0.341 0.348 -0.007 4.22e-01
GCSE PRScs.10FCVal lassosum.10FCVal 0.410 0.407 0.003 4.22e-01 0.341 0.348 -0.007 3.70e-01
GCSE LDpred2.MultiPRS lassosum.10FCVal 0.412 0.407 0.005 7.42e-01 0.339 0.348 -0.009 2.12e-01
GCSE lassosum.10FCVal lassosum.10FCVal 0.407 0.407 0.000 1.00e+00 0.348 0.348 0.000 1.00e+00
GCSE PRScs.PseudoVal lassosum.10FCVal 0.397 0.407 -0.010 2.12e-03 0.351 0.348 0.003 6.16e-01
GCSE DBSLMM.PseudoVal lassosum.10FCVal 0.401 0.407 -0.006 1.61e-01 0.337 0.348 -0.011 2.43e-01
GCSE SBLUP.Inf lassosum.10FCVal 0.400 0.407 -0.008 1.14e-01 0.335 0.348 -0.013 1.98e-01
GCSE LDpred2.Inf lassosum.10FCVal 0.405 0.407 -0.002 6.46e-01 0.331 0.348 -0.017 5.47e-02
GCSE pT+clump.10FCVal lassosum.10FCVal 0.373 0.407 -0.034 3.87e-07 0.311 0.348 -0.036 9.69e-03
GCSE LDpred2.10FCVal lassosum.10FCVal 0.412 0.407 0.004 1.62e-01 0.342 0.348 -0.006 3.59e-01
GCSE lassosum.MultiPRS lassosum.10FCVal 0.411 0.407 0.004 8.11e-01 0.347 0.348 -0.001 7.97e-01
GCSE LDpred1.10FCVal lassosum.10FCVal 0.402 0.407 -0.005 2.45e-01 0.330 0.348 -0.017 7.38e-02
GCSE All.MultiPRS lassosum.10FCVal 0.417 0.407 0.010 5.29e-01 0.347 0.348 -0.001 8.42e-01
GCSE SBayesR.PseudoVal lassosum.10FCVal 0.397 0.407 -0.011 1.91e-02 0.331 0.348 -0.017 8.58e-02
GCSE lassosum.PseudoVal lassosum.10FCVal 0.321 0.407 -0.087 1.70e-32 0.276 0.348 -0.072 3.58e-06
GCSE pT+clump.MultiPRS lassosum.10FCVal 0.381 0.407 -0.027 1.06e-01 0.328 0.348 -0.019 1.07e-01
GCSE LDpred2.PseudoVal lassosum.10FCVal 0.406 0.407 -0.002 6.94e-01 0.332 0.348 -0.015 6.39e-02
GCSE LDpred1.MultiPRS lassosum.10FCVal 0.409 0.407 0.002 9.10e-01 0.340 0.348 -0.008 3.29e-01
GCSE PRScs.MultiPRS lassosum.10FCVal 0.413 0.407 0.006 7.18e-01 0.346 0.348 -0.002 7.59e-01
GCSE lassosum.PseudoVal lassosum.PseudoVal 0.321 0.321 0.000 1.00e+00 0.276 0.276 0.000 1.00e+00
GCSE pT+clump.MultiPRS lassosum.PseudoVal 0.381 0.321 0.060 3.70e-04 0.328 0.276 0.052 5.51e-03
GCSE LDpred2.Inf lassosum.PseudoVal 0.405 0.321 0.085 1.54e-18 0.331 0.276 0.055 6.84e-03
GCSE SBayesR.PseudoVal lassosum.PseudoVal 0.397 0.321 0.076 2.14e-37 0.331 0.276 0.055 1.49e-05
GCSE PRScs.MultiPRS lassosum.PseudoVal 0.413 0.321 0.092 1.67e-08 0.346 0.276 0.070 6.81e-05
GCSE SBLUP.Inf lassosum.PseudoVal 0.400 0.321 0.079 3.28e-15 0.335 0.276 0.059 5.25e-03
GCSE lassosum.MultiPRS lassosum.PseudoVal 0.411 0.321 0.091 3.52e-08 0.347 0.276 0.071 2.48e-05
GCSE PRScs.10FCVal lassosum.PseudoVal 0.410 0.321 0.090 9.90e-22 0.341 0.276 0.064 1.14e-03
GCSE LDpred2.MultiPRS lassosum.PseudoVal 0.412 0.321 0.092 2.37e-08 0.339 0.276 0.063 2.25e-04
GCSE PRScs.PseudoVal lassosum.PseudoVal 0.397 0.321 0.077 7.69e-31 0.351 0.276 0.075 4.42e-08
GCSE LDpred2.PseudoVal lassosum.PseudoVal 0.406 0.321 0.085 2.71e-19 0.332 0.276 0.056 4.53e-03
GCSE LDpred1.MultiPRS lassosum.PseudoVal 0.409 0.321 0.089 7.46e-08 0.340 0.276 0.064 1.37e-03
GCSE pT+clump.10FCVal lassosum.PseudoVal 0.373 0.321 0.052 1.02e-06 0.311 0.276 0.035 1.22e-01
GCSE All.MultiPRS lassosum.PseudoVal 0.417 0.321 0.097 4.07e-09 0.347 0.276 0.071 3.89e-05
GCSE LDpred1.Inf lassosum.PseudoVal 0.408 0.321 0.087 2.61e-20 0.341 0.276 0.065 1.22e-03
GCSE DBSLMM.PseudoVal lassosum.PseudoVal 0.401 0.321 0.081 3.95e-22 0.337 0.276 0.061 6.21e-04
GCSE LDpred1.10FCVal lassosum.PseudoVal 0.402 0.321 0.081 1.52e-17 0.330 0.276 0.054 6.77e-03
GCSE lassosum.10FCVal lassosum.PseudoVal 0.407 0.321 0.087 1.70e-32 0.348 0.276 0.072 3.58e-06
GCSE LDpred2.10FCVal lassosum.PseudoVal 0.412 0.321 0.091 5.61e-28 0.342 0.276 0.066 1.45e-04
GCSE LDpred2.10FCVal LDpred1.MultiPRS 0.412 0.409 0.002 8.78e-01 0.342 0.340 0.002 7.42e-01
GCSE PRScs.PseudoVal LDpred1.MultiPRS 0.397 0.409 -0.012 4.63e-01 0.351 0.340 0.011 2.69e-01
GCSE LDpred2.Inf LDpred1.MultiPRS 0.405 0.409 -0.004 8.13e-01 0.331 0.340 -0.009 1.47e-01
GCSE pT+clump.10FCVal LDpred1.MultiPRS 0.373 0.409 -0.036 2.56e-02 0.311 0.340 -0.028 3.00e-02
GCSE SBayesR.PseudoVal LDpred1.MultiPRS 0.397 0.409 -0.013 4.34e-01 0.331 0.340 -0.009 4.97e-01
GCSE All.MultiPRS LDpred1.MultiPRS 0.417 0.409 0.008 6.07e-01 0.347 0.340 0.007 2.45e-01
GCSE LDpred1.10FCVal LDpred1.MultiPRS 0.402 0.409 -0.007 6.55e-01 0.330 0.340 -0.009 7.63e-02
GCSE LDpred1.MultiPRS LDpred1.MultiPRS 0.409 0.409 0.000 1.00e+00 0.340 0.340 0.000 1.00e+00
GCSE PRScs.10FCVal LDpred1.MultiPRS 0.410 0.409 0.001 9.38e-01 0.341 0.340 0.001 8.96e-01
GCSE lassosum.10FCVal LDpred1.MultiPRS 0.407 0.409 -0.002 9.10e-01 0.348 0.340 0.008 3.29e-01
GCSE pT+clump.MultiPRS LDpred1.MultiPRS 0.381 0.409 -0.028 8.01e-02 0.328 0.340 -0.012 3.54e-01
GCSE LDpred1.Inf LDpred1.MultiPRS 0.408 0.409 -0.001 9.32e-01 0.341 0.340 0.001 6.81e-01
GCSE lassosum.MultiPRS LDpred1.MultiPRS 0.411 0.409 0.002 6.04e-01 0.347 0.340 0.007 3.80e-01
GCSE PRScs.MultiPRS LDpred1.MultiPRS 0.413 0.409 0.004 1.89e-01 0.346 0.340 0.006 3.37e-01
GCSE lassosum.PseudoVal LDpred1.MultiPRS 0.321 0.409 -0.089 7.46e-08 0.276 0.340 -0.064 1.37e-03
GCSE LDpred2.PseudoVal LDpred1.MultiPRS 0.406 0.409 -0.003 8.31e-01 0.332 0.340 -0.007 2.15e-01
GCSE DBSLMM.PseudoVal LDpred1.MultiPRS 0.401 0.409 -0.008 6.22e-01 0.337 0.340 -0.003 7.50e-01
GCSE LDpred2.MultiPRS LDpred1.MultiPRS 0.412 0.409 0.003 8.30e-01 0.339 0.340 -0.001 9.05e-01
GCSE SBLUP.Inf LDpred1.MultiPRS 0.400 0.409 -0.010 5.52e-01 0.335 0.340 -0.005 4.80e-01
GCSE All.MultiPRS LDpred1.Inf 0.417 0.408 0.010 5.46e-01 0.347 0.341 0.006 4.01e-01
GCSE LDpred2.PseudoVal LDpred1.Inf 0.406 0.408 -0.002 4.65e-01 0.332 0.341 -0.009 1.41e-01
GCSE SBayesR.PseudoVal LDpred1.Inf 0.397 0.408 -0.011 7.41e-02 0.331 0.341 -0.010 4.47e-01
GCSE LDpred2.MultiPRS LDpred1.Inf 0.412 0.408 0.005 7.63e-01 0.339 0.341 -0.002 7.79e-01
GCSE PRScs.PseudoVal LDpred1.Inf 0.397 0.408 -0.010 3.09e-02 0.351 0.341 0.010 3.37e-01
GCSE LDpred1.Inf LDpred1.Inf 0.408 0.408 0.000 1.00e+00 0.341 0.341 0.000 1.00e+00
GCSE pT+clump.10FCVal LDpred1.Inf 0.373 0.408 -0.035 1.52e-08 0.311 0.341 -0.030 2.37e-02
GCSE PRScs.MultiPRS LDpred1.Inf 0.413 0.408 0.005 7.39e-01 0.346 0.341 0.005 4.73e-01
GCSE lassosum.10FCVal LDpred1.Inf 0.407 0.408 0.000 9.14e-01 0.348 0.341 0.007 4.22e-01
GCSE pT+clump.MultiPRS LDpred1.Inf 0.381 0.408 -0.027 9.98e-02 0.328 0.341 -0.013 3.07e-01
GCSE LDpred1.MultiPRS LDpred1.Inf 0.409 0.408 0.001 9.32e-01 0.340 0.341 -0.001 6.81e-01
GCSE PRScs.10FCVal LDpred1.Inf 0.410 0.408 0.003 3.87e-01 0.341 0.341 0.000 9.39e-01
GCSE LDpred2.Inf LDpred1.Inf 0.405 0.408 -0.002 4.09e-01 0.331 0.341 -0.010 9.52e-02
GCSE SBLUP.Inf LDpred1.Inf 0.400 0.408 -0.008 2.27e-02 0.335 0.341 -0.006 4.01e-01
GCSE DBSLMM.PseudoVal LDpred1.Inf 0.401 0.408 -0.006 1.45e-01 0.337 0.341 -0.004 6.60e-01
GCSE lassosum.MultiPRS LDpred1.Inf 0.411 0.408 0.003 8.32e-01 0.347 0.341 0.006 4.86e-01
GCSE LDpred1.10FCVal LDpred1.Inf 0.402 0.408 -0.006 9.78e-02 0.330 0.341 -0.011 1.54e-01
GCSE lassosum.PseudoVal LDpred1.Inf 0.321 0.408 -0.087 2.61e-20 0.276 0.341 -0.065 1.22e-03
GCSE LDpred2.10FCVal LDpred1.Inf 0.412 0.408 0.004 2.49e-01 0.342 0.341 0.001 8.84e-01
GCSE LDpred1.Inf LDpred1.10FCVal 0.408 0.402 0.006 9.78e-02 0.341 0.330 0.011 1.54e-01
GCSE PRScs.MultiPRS LDpred1.10FCVal 0.413 0.402 0.011 4.87e-01 0.346 0.330 0.015 5.88e-02
GCSE LDpred1.10FCVal LDpred1.10FCVal 0.402 0.402 0.000 1.00e+00 0.330 0.330 0.000 1.00e+00
GCSE All.MultiPRS LDpred1.10FCVal 0.417 0.402 0.015 3.35e-01 0.347 0.330 0.016 3.81e-02
GCSE SBayesR.PseudoVal LDpred1.10FCVal 0.397 0.402 -0.005 4.08e-01 0.331 0.330 0.000 9.75e-01
GCSE DBSLMM.PseudoVal LDpred1.10FCVal 0.401 0.402 -0.001 8.86e-01 0.337 0.330 0.006 5.42e-01
GCSE pT+clump.MultiPRS LDpred1.10FCVal 0.381 0.402 -0.021 1.97e-01 0.328 0.330 -0.002 8.69e-01
GCSE lassosum.MultiPRS LDpred1.10FCVal 0.411 0.402 0.009 5.66e-01 0.347 0.330 0.016 8.28e-02
GCSE PRScs.10FCVal LDpred1.10FCVal 0.410 0.402 0.008 2.62e-02 0.341 0.330 0.010 2.04e-01
GCSE lassosum.PseudoVal LDpred1.10FCVal 0.321 0.402 -0.081 1.52e-17 0.276 0.330 -0.054 6.77e-03
GCSE SBLUP.Inf LDpred1.10FCVal 0.400 0.402 -0.002 5.73e-01 0.335 0.330 0.004 6.50e-01
GCSE LDpred2.PseudoVal LDpred1.10FCVal 0.406 0.402 0.004 3.47e-01 0.332 0.330 0.002 8.25e-01
GCSE pT+clump.10FCVal LDpred1.10FCVal 0.373 0.402 -0.029 1.56e-05 0.311 0.330 -0.019 1.77e-01
GCSE LDpred2.MultiPRS LDpred1.10FCVal 0.412 0.402 0.011 5.06e-01 0.339 0.330 0.008 3.59e-01
GCSE PRScs.PseudoVal LDpred1.10FCVal 0.397 0.402 -0.005 3.81e-01 0.351 0.330 0.021 6.81e-02
GCSE LDpred2.10FCVal LDpred1.10FCVal 0.412 0.402 0.010 2.10e-02 0.342 0.330 0.012 1.88e-01
GCSE LDpred1.MultiPRS LDpred1.10FCVal 0.409 0.402 0.007 6.55e-01 0.340 0.330 0.009 7.63e-02
GCSE LDpred2.Inf LDpred1.10FCVal 0.405 0.402 0.003 4.05e-01 0.331 0.330 0.000 9.74e-01
GCSE lassosum.10FCVal LDpred1.10FCVal 0.407 0.402 0.005 2.45e-01 0.348 0.330 0.017 7.38e-02
GCSE LDpred1.Inf LDpred2.MultiPRS 0.408 0.412 -0.005 7.63e-01 0.341 0.339 0.002 7.79e-01
GCSE DBSLMM.PseudoVal LDpred2.MultiPRS 0.401 0.412 -0.011 4.79e-01 0.337 0.339 -0.002 8.05e-01
GCSE SBLUP.Inf LDpred2.MultiPRS 0.400 0.412 -0.013 4.17e-01 0.335 0.339 -0.004 6.48e-01
GCSE LDpred2.Inf LDpred2.MultiPRS 0.405 0.412 -0.007 6.51e-01 0.331 0.339 -0.008 1.10e-01
GCSE pT+clump.10FCVal LDpred2.MultiPRS 0.373 0.412 -0.040 1.41e-02 0.311 0.339 -0.028 4.78e-02
GCSE LDpred2.10FCVal LDpred2.MultiPRS 0.412 0.412 -0.001 9.50e-01 0.342 0.339 0.003 2.48e-01
GCSE PRScs.PseudoVal LDpred2.MultiPRS 0.397 0.412 -0.015 3.42e-01 0.351 0.339 0.012 1.31e-01
GCSE LDpred1.10FCVal LDpred2.MultiPRS 0.402 0.412 -0.011 5.06e-01 0.330 0.339 -0.008 3.59e-01
GCSE All.MultiPRS LDpred2.MultiPRS 0.417 0.412 0.005 1.61e-02 0.347 0.339 0.008 6.48e-02
GCSE SBayesR.PseudoVal LDpred2.MultiPRS 0.397 0.412 -0.016 3.20e-01 0.331 0.339 -0.008 4.36e-01
GCSE lassosum.PseudoVal LDpred2.MultiPRS 0.321 0.412 -0.092 2.37e-08 0.276 0.339 -0.063 2.25e-04
GCSE pT+clump.MultiPRS LDpred2.MultiPRS 0.381 0.412 -0.032 4.60e-02 0.328 0.339 -0.011 3.77e-01
GCSE lassosum.MultiPRS LDpred2.MultiPRS 0.411 0.412 -0.001 9.29e-01 0.347 0.339 0.008 2.75e-01
GCSE PRScs.10FCVal LDpred2.MultiPRS 0.410 0.412 -0.002 8.90e-01 0.341 0.339 0.002 8.28e-01
GCSE PRScs.MultiPRS LDpred2.MultiPRS 0.413 0.412 0.001 9.75e-01 0.346 0.339 0.007 2.80e-01
GCSE lassosum.10FCVal LDpred2.MultiPRS 0.407 0.412 -0.005 7.42e-01 0.348 0.339 0.009 2.12e-01
GCSE LDpred2.PseudoVal LDpred2.MultiPRS 0.406 0.412 -0.007 6.68e-01 0.332 0.339 -0.007 1.83e-01
GCSE LDpred1.MultiPRS LDpred2.MultiPRS 0.409 0.412 -0.003 8.30e-01 0.340 0.339 0.001 9.05e-01
GCSE LDpred2.MultiPRS LDpred2.MultiPRS 0.412 0.412 0.000 1.00e+00 0.339 0.339 0.000 1.00e+00
GCSE LDpred1.Inf LDpred2.10FCVal 0.408 0.412 -0.004 2.49e-01 0.341 0.342 -0.001 8.84e-01
GCSE PRScs.MultiPRS LDpred2.10FCVal 0.413 0.412 0.001 9.25e-01 0.346 0.342 0.004 5.55e-01
GCSE LDpred2.MultiPRS LDpred2.10FCVal 0.412 0.412 0.001 9.50e-01 0.339 0.342 -0.003 2.48e-01
GCSE PRScs.PseudoVal LDpred2.10FCVal 0.397 0.412 -0.014 2.22e-04 0.351 0.342 0.009 2.62e-01
GCSE LDpred2.10FCVal LDpred2.10FCVal 0.412 0.412 0.000 1.00e+00 0.342 0.342 0.000 1.00e+00
GCSE lassosum.MultiPRS LDpred2.10FCVal 0.411 0.412 0.000 9.78e-01 0.347 0.342 0.005 4.81e-01
GCSE LDpred1.10FCVal LDpred2.10FCVal 0.402 0.412 -0.010 2.10e-02 0.330 0.342 -0.012 1.88e-01
GCSE All.MultiPRS LDpred2.10FCVal 0.417 0.412 0.006 7.17e-01 0.347 0.342 0.004 3.38e-01
GCSE SBayesR.PseudoVal LDpred2.10FCVal 0.397 0.412 -0.015 2.80e-03 0.331 0.342 -0.011 2.89e-01
GCSE DBSLMM.PseudoVal LDpred2.10FCVal 0.401 0.412 -0.010 1.61e-02 0.337 0.342 -0.005 5.58e-01
GCSE pT+clump.MultiPRS LDpred2.10FCVal 0.381 0.412 -0.031 6.06e-02 0.328 0.342 -0.014 2.48e-01
GCSE lassosum.10FCVal LDpred2.10FCVal 0.407 0.412 -0.004 1.62e-01 0.348 0.342 0.006 3.59e-01
GCSE PRScs.10FCVal LDpred2.10FCVal 0.410 0.412 -0.001 7.35e-01 0.341 0.342 -0.002 8.39e-01
GCSE lassosum.PseudoVal LDpred2.10FCVal 0.321 0.412 -0.091 5.61e-28 0.276 0.342 -0.066 1.45e-04
GCSE SBLUP.Inf LDpred2.10FCVal 0.400 0.412 -0.012 4.75e-03 0.335 0.342 -0.007 4.10e-01
GCSE LDpred2.PseudoVal LDpred2.10FCVal 0.406 0.412 -0.006 7.62e-03 0.332 0.342 -0.010 3.31e-02
GCSE pT+clump.10FCVal LDpred2.10FCVal 0.373 0.412 -0.039 3.35e-09 0.311 0.342 -0.031 2.38e-02
GCSE LDpred2.Inf LDpred2.10FCVal 0.405 0.412 -0.006 7.61e-03 0.331 0.342 -0.011 2.17e-02
GCSE LDpred1.MultiPRS LDpred2.10FCVal 0.409 0.412 -0.002 8.78e-01 0.340 0.342 -0.002 7.42e-01
GCSE lassosum.PseudoVal LDpred2.PseudoVal 0.321 0.406 -0.085 2.71e-19 0.276 0.332 -0.056 4.53e-03
GCSE SBLUP.Inf LDpred2.PseudoVal 0.400 0.406 -0.006 1.01e-01 0.335 0.332 0.002 7.78e-01
GCSE SBayesR.PseudoVal LDpred2.PseudoVal 0.397 0.406 -0.009 1.48e-01 0.331 0.332 -0.001 9.13e-01
GCSE All.MultiPRS LDpred2.PseudoVal 0.417 0.406 0.012 4.66e-01 0.347 0.332 0.014 2.51e-02
GCSE PRScs.PseudoVal LDpred2.PseudoVal 0.397 0.406 -0.008 9.07e-02 0.351 0.332 0.019 7.27e-02
GCSE lassosum.MultiPRS LDpred2.PseudoVal 0.411 0.406 0.005 7.34e-01 0.347 0.332 0.014 9.52e-02
GCSE PRScs.MultiPRS LDpred2.PseudoVal 0.413 0.406 0.007 6.45e-01 0.346 0.332 0.013 6.28e-02
GCSE LDpred2.MultiPRS LDpred2.PseudoVal 0.412 0.406 0.007 6.68e-01 0.339 0.332 0.007 1.83e-01
GCSE PRScs.10FCVal LDpred2.PseudoVal 0.410 0.406 0.005 1.77e-01 0.341 0.332 0.008 2.59e-01
GCSE LDpred2.PseudoVal LDpred2.PseudoVal 0.406 0.406 0.000 1.00e+00 0.332 0.332 0.000 1.00e+00
GCSE pT+clump.MultiPRS LDpred2.PseudoVal 0.381 0.406 -0.025 1.29e-01 0.328 0.332 -0.004 7.53e-01
GCSE pT+clump.10FCVal LDpred2.PseudoVal 0.373 0.406 -0.033 5.80e-07 0.311 0.332 -0.021 1.27e-01
GCSE lassosum.10FCVal LDpred2.PseudoVal 0.407 0.406 0.002 6.94e-01 0.348 0.332 0.015 6.39e-02
GCSE LDpred1.Inf LDpred2.PseudoVal 0.408 0.406 0.002 4.65e-01 0.341 0.332 0.009 1.41e-01
GCSE LDpred1.MultiPRS LDpred2.PseudoVal 0.409 0.406 0.003 8.31e-01 0.340 0.332 0.007 2.15e-01
GCSE LDpred1.10FCVal LDpred2.PseudoVal 0.402 0.406 -0.004 3.47e-01 0.330 0.332 -0.002 8.25e-01
GCSE LDpred2.Inf LDpred2.PseudoVal 0.405 0.406 0.000 4.25e-01 0.331 0.332 -0.002 1.18e-01
GCSE LDpred2.10FCVal LDpred2.PseudoVal 0.412 0.406 0.006 7.62e-03 0.342 0.332 0.010 3.31e-02
GCSE DBSLMM.PseudoVal LDpred2.PseudoVal 0.401 0.406 -0.004 3.40e-01 0.337 0.332 0.004 6.50e-01
GCSE pT+clump.MultiPRS LDpred2.Inf 0.381 0.405 -0.025 1.34e-01 0.328 0.331 -0.002 8.51e-01
GCSE lassosum.MultiPRS LDpred2.Inf 0.411 0.405 0.006 7.16e-01 0.347 0.331 0.016 7.29e-02
GCSE SBayesR.PseudoVal LDpred2.Inf 0.397 0.405 -0.009 1.78e-01 0.331 0.331 0.000 9.91e-01
GCSE All.MultiPRS LDpred2.Inf 0.417 0.405 0.012 4.52e-01 0.347 0.331 0.016 1.59e-02
GCSE SBLUP.Inf LDpred2.Inf 0.400 0.405 -0.006 1.30e-01 0.335 0.331 0.004 6.36e-01
GCSE LDpred2.PseudoVal LDpred2.Inf 0.406 0.405 0.000 4.25e-01 0.332 0.331 0.002 1.18e-01
GCSE PRScs.MultiPRS LDpred2.Inf 0.413 0.405 0.008 6.28e-01 0.346 0.331 0.015 4.37e-02
GCSE LDpred2.MultiPRS LDpred2.Inf 0.412 0.405 0.007 6.51e-01 0.339 0.331 0.008 1.10e-01
GCSE PRScs.10FCVal LDpred2.Inf 0.410 0.405 0.005 1.46e-01 0.341 0.331 0.010 1.78e-01
GCSE LDpred1.Inf LDpred2.Inf 0.408 0.405 0.002 4.09e-01 0.341 0.331 0.010 9.52e-02
GCSE LDpred1.MultiPRS LDpred2.Inf 0.409 0.405 0.004 8.13e-01 0.340 0.331 0.009 1.47e-01
GCSE pT+clump.10FCVal LDpred2.Inf 0.373 0.405 -0.032 9.19e-07 0.311 0.331 -0.019 1.62e-01
GCSE lassosum.10FCVal LDpred2.Inf 0.407 0.405 0.002 6.46e-01 0.348 0.331 0.017 5.47e-02
GCSE PRScs.PseudoVal LDpred2.Inf 0.397 0.405 -0.008 1.21e-01 0.351 0.331 0.020 6.27e-02
GCSE DBSLMM.PseudoVal LDpred2.Inf 0.401 0.405 -0.004 3.90e-01 0.337 0.331 0.006 5.44e-01
GCSE LDpred1.10FCVal LDpred2.Inf 0.402 0.405 -0.003 4.05e-01 0.330 0.331 0.000 9.74e-01
GCSE LDpred2.Inf LDpred2.Inf 0.405 0.405 0.000 1.00e+00 0.331 0.331 0.000 1.00e+00
GCSE lassosum.PseudoVal LDpred2.Inf 0.321 0.405 -0.085 1.54e-18 0.276 0.331 -0.055 6.84e-03
GCSE LDpred2.10FCVal LDpred2.Inf 0.412 0.405 0.006 7.61e-03 0.342 0.331 0.011 2.17e-02
GCSE PRScs.10FCVal PRScs.MultiPRS 0.410 0.413 -0.003 8.65e-01 0.341 0.346 -0.005 9.20e-02
GCSE LDpred1.10FCVal PRScs.MultiPRS 0.402 0.413 -0.011 4.87e-01 0.330 0.346 -0.015 5.88e-02
GCSE lassosum.MultiPRS PRScs.MultiPRS 0.411 0.413 -0.002 4.70e-01 0.347 0.346 0.001 8.58e-01
GCSE LDpred2.MultiPRS PRScs.MultiPRS 0.412 0.413 -0.001 9.75e-01 0.339 0.346 -0.007 2.80e-01
GCSE All.MultiPRS PRScs.MultiPRS 0.417 0.413 0.004 7.89e-01 0.347 0.346 0.001 8.67e-01
GCSE PRScs.PseudoVal PRScs.MultiPRS 0.397 0.413 -0.016 3.26e-01 0.351 0.346 0.005 4.54e-01
GCSE LDpred1.MultiPRS PRScs.MultiPRS 0.409 0.413 -0.004 1.89e-01 0.340 0.346 -0.006 3.37e-01
GCSE pT+clump.MultiPRS PRScs.MultiPRS 0.381 0.413 -0.032 4.58e-02 0.328 0.346 -0.018 1.21e-01
GCSE lassosum.10FCVal PRScs.MultiPRS 0.407 0.413 -0.006 7.18e-01 0.348 0.346 0.002 7.59e-01
GCSE SBayesR.PseudoVal PRScs.MultiPRS 0.397 0.413 -0.016 3.02e-01 0.331 0.346 -0.015 1.59e-01
GCSE DBSLMM.PseudoVal PRScs.MultiPRS 0.401 0.413 -0.012 4.59e-01 0.337 0.346 -0.009 1.97e-01
GCSE SBLUP.Inf PRScs.MultiPRS 0.400 0.413 -0.013 3.99e-01 0.335 0.346 -0.011 1.98e-01
GCSE LDpred2.Inf PRScs.MultiPRS 0.405 0.413 -0.008 6.28e-01 0.331 0.346 -0.015 4.37e-02
GCSE pT+clump.10FCVal PRScs.MultiPRS 0.373 0.413 -0.040 1.30e-02 0.311 0.346 -0.035 8.04e-03
GCSE LDpred2.10FCVal PRScs.MultiPRS 0.412 0.413 -0.001 9.25e-01 0.342 0.346 -0.004 5.55e-01
GCSE lassosum.PseudoVal PRScs.MultiPRS 0.321 0.413 -0.092 1.67e-08 0.276 0.346 -0.070 6.81e-05
GCSE LDpred2.PseudoVal PRScs.MultiPRS 0.406 0.413 -0.007 6.45e-01 0.332 0.346 -0.013 6.28e-02
GCSE LDpred1.Inf PRScs.MultiPRS 0.408 0.413 -0.005 7.39e-01 0.341 0.346 -0.005 4.73e-01
GCSE PRScs.MultiPRS PRScs.MultiPRS 0.413 0.413 0.000 1.00e+00 0.346 0.346 0.000 1.00e+00
GCSE LDpred2.PseudoVal PRScs.10FCVal 0.406 0.410 -0.005 1.77e-01 0.332 0.341 -0.008 2.59e-01
GCSE PRScs.10FCVal PRScs.10FCVal 0.410 0.410 0.000 1.00e+00 0.341 0.341 0.000 1.00e+00
GCSE LDpred2.MultiPRS PRScs.10FCVal 0.412 0.410 0.002 8.90e-01 0.339 0.341 -0.002 8.28e-01
GCSE pT+clump.MultiPRS PRScs.10FCVal 0.381 0.410 -0.030 7.06e-02 0.328 0.341 -0.012 3.08e-01
GCSE LDpred1.Inf PRScs.10FCVal 0.408 0.410 -0.003 3.87e-01 0.341 0.341 0.000 9.39e-01
GCSE LDpred1.MultiPRS PRScs.10FCVal 0.409 0.410 -0.001 9.38e-01 0.340 0.341 -0.001 8.96e-01
GCSE pT+clump.10FCVal PRScs.10FCVal 0.373 0.410 -0.037 7.12e-10 0.311 0.341 -0.029 2.29e-02
GCSE lassosum.10FCVal PRScs.10FCVal 0.407 0.410 -0.003 4.22e-01 0.348 0.341 0.007 3.70e-01
GCSE PRScs.PseudoVal PRScs.10FCVal 0.397 0.410 -0.013 3.15e-03 0.351 0.341 0.011 2.69e-01
GCSE DBSLMM.PseudoVal PRScs.10FCVal 0.401 0.410 -0.009 1.71e-02 0.337 0.341 -0.004 6.46e-01
GCSE SBLUP.Inf PRScs.10FCVal 0.400 0.410 -0.011 5.14e-03 0.335 0.341 -0.006 4.76e-01
GCSE LDpred2.Inf PRScs.10FCVal 0.405 0.410 -0.005 1.46e-01 0.331 0.341 -0.010 1.78e-01
GCSE lassosum.PseudoVal PRScs.10FCVal 0.321 0.410 -0.090 9.90e-22 0.276 0.341 -0.064 1.14e-03
GCSE LDpred2.10FCVal PRScs.10FCVal 0.412 0.410 0.001 7.35e-01 0.342 0.341 0.002 8.39e-01
GCSE lassosum.MultiPRS PRScs.10FCVal 0.411 0.410 0.001 9.61e-01 0.347 0.341 0.006 3.58e-01
GCSE LDpred1.10FCVal PRScs.10FCVal 0.402 0.410 -0.008 2.62e-02 0.330 0.341 -0.010 2.04e-01
GCSE All.MultiPRS PRScs.10FCVal 0.417 0.410 0.007 6.61e-01 0.347 0.341 0.006 2.92e-01
GCSE SBayesR.PseudoVal PRScs.10FCVal 0.397 0.410 -0.014 2.46e-02 0.331 0.341 -0.010 4.56e-01
GCSE PRScs.MultiPRS PRScs.10FCVal 0.413 0.410 0.003 8.65e-01 0.346 0.341 0.005 9.20e-02
GCSE All.MultiPRS PRScs.PseudoVal 0.417 0.397 0.020 2.11e-01 0.347 0.351 -0.005 5.38e-01
GCSE pT+clump.MultiPRS PRScs.PseudoVal 0.381 0.397 -0.017 3.12e-01 0.328 0.351 -0.023 6.07e-02
GCSE LDpred2.PseudoVal PRScs.PseudoVal 0.406 0.397 0.008 9.07e-02 0.332 0.351 -0.019 7.27e-02
GCSE SBayesR.PseudoVal PRScs.PseudoVal 0.397 0.397 -0.001 8.33e-01 0.331 0.351 -0.020 8.45e-03
GCSE LDpred2.MultiPRS PRScs.PseudoVal 0.412 0.397 0.015 3.42e-01 0.339 0.351 -0.012 1.31e-01
GCSE SBLUP.Inf PRScs.PseudoVal 0.400 0.397 0.002 6.98e-01 0.335 0.351 -0.017 1.73e-01
GCSE LDpred1.Inf PRScs.PseudoVal 0.408 0.397 0.010 3.09e-02 0.341 0.351 -0.010 3.37e-01
GCSE PRScs.10FCVal PRScs.PseudoVal 0.410 0.397 0.013 3.15e-03 0.341 0.351 -0.011 2.69e-01
GCSE LDpred2.Inf PRScs.PseudoVal 0.405 0.397 0.008 1.21e-01 0.331 0.351 -0.020 6.27e-02
GCSE PRScs.PseudoVal PRScs.PseudoVal 0.397 0.397 0.000 1.00e+00 0.351 0.351 0.000 1.00e+00
GCSE LDpred2.10FCVal PRScs.PseudoVal 0.412 0.397 0.014 2.22e-04 0.342 0.351 -0.009 2.62e-01
GCSE pT+clump.10FCVal PRScs.PseudoVal 0.373 0.397 -0.024 6.09e-04 0.311 0.351 -0.040 8.58e-03
GCSE PRScs.MultiPRS PRScs.PseudoVal 0.413 0.397 0.016 3.26e-01 0.346 0.351 -0.005 4.54e-01
GCSE lassosum.10FCVal PRScs.PseudoVal 0.407 0.397 0.010 2.12e-03 0.348 0.351 -0.003 6.16e-01
GCSE lassosum.PseudoVal PRScs.PseudoVal 0.321 0.397 -0.077 7.69e-31 0.276 0.351 -0.075 4.42e-08
GCSE LDpred1.MultiPRS PRScs.PseudoVal 0.409 0.397 0.012 4.63e-01 0.340 0.351 -0.011 2.69e-01
GCSE lassosum.MultiPRS PRScs.PseudoVal 0.411 0.397 0.014 3.89e-01 0.347 0.351 -0.004 5.77e-01
GCSE LDpred1.10FCVal PRScs.PseudoVal 0.402 0.397 0.005 3.81e-01 0.330 0.351 -0.021 6.81e-02
GCSE DBSLMM.PseudoVal PRScs.PseudoVal 0.401 0.397 0.004 3.38e-01 0.337 0.351 -0.014 9.88e-02
GCSE All.MultiPRS pT+clump.MultiPRS 0.417 0.381 0.037 2.16e-02 0.347 0.328 0.018 7.70e-02
GCSE SBayesR.PseudoVal pT+clump.MultiPRS 0.397 0.381 0.016 3.35e-01 0.331 0.328 0.003 8.47e-01
GCSE LDpred1.MultiPRS pT+clump.MultiPRS 0.409 0.381 0.028 8.01e-02 0.340 0.328 0.012 3.54e-01
GCSE pT+clump.MultiPRS pT+clump.MultiPRS 0.381 0.381 0.000 1.00e+00 0.328 0.328 0.000 1.00e+00
GCSE lassosum.10FCVal pT+clump.MultiPRS 0.407 0.381 0.027 1.06e-01 0.348 0.328 0.019 1.07e-01
GCSE PRScs.10FCVal pT+clump.MultiPRS 0.410 0.381 0.030 7.06e-02 0.341 0.328 0.012 3.08e-01
GCSE DBSLMM.PseudoVal pT+clump.MultiPRS 0.401 0.381 0.021 2.13e-01 0.337 0.328 0.009 4.68e-01
GCSE SBLUP.Inf pT+clump.MultiPRS 0.400 0.381 0.019 2.51e-01 0.335 0.328 0.006 6.38e-01
GCSE LDpred2.Inf pT+clump.MultiPRS 0.405 0.381 0.025 1.34e-01 0.331 0.328 0.002 8.51e-01
GCSE pT+clump.10FCVal pT+clump.MultiPRS 0.373 0.381 -0.008 6.40e-01 0.311 0.328 -0.017 4.87e-03
GCSE LDpred2.10FCVal pT+clump.MultiPRS 0.412 0.381 0.031 6.06e-02 0.342 0.328 0.014 2.48e-01
GCSE PRScs.PseudoVal pT+clump.MultiPRS 0.397 0.381 0.017 3.12e-01 0.351 0.328 0.023 6.07e-02
GCSE LDpred1.10FCVal pT+clump.MultiPRS 0.402 0.381 0.021 1.97e-01 0.330 0.328 0.002 8.69e-01
GCSE LDpred1.Inf pT+clump.MultiPRS 0.408 0.381 0.027 9.98e-02 0.341 0.328 0.013 3.07e-01
GCSE PRScs.MultiPRS pT+clump.MultiPRS 0.413 0.381 0.032 4.58e-02 0.346 0.328 0.018 1.21e-01
GCSE lassosum.PseudoVal pT+clump.MultiPRS 0.321 0.381 -0.060 3.70e-04 0.276 0.328 -0.052 5.51e-03
GCSE LDpred2.PseudoVal pT+clump.MultiPRS 0.406 0.381 0.025 1.29e-01 0.332 0.328 0.004 7.53e-01
GCSE lassosum.MultiPRS pT+clump.MultiPRS 0.411 0.381 0.030 6.07e-02 0.347 0.328 0.019 1.13e-01
GCSE LDpred2.MultiPRS pT+clump.MultiPRS 0.412 0.381 0.032 4.60e-02 0.339 0.328 0.011 3.77e-01
GCSE LDpred2.10FCVal pT+clump.10FCVal 0.412 0.373 0.039 3.35e-09 0.342 0.311 0.031 2.38e-02
GCSE pT+clump.MultiPRS pT+clump.10FCVal 0.381 0.373 0.008 6.40e-01 0.328 0.311 0.017 4.87e-03
GCSE LDpred2.Inf pT+clump.10FCVal 0.405 0.373 0.032 9.19e-07 0.331 0.311 0.019 1.62e-01
GCSE SBayesR.PseudoVal pT+clump.10FCVal 0.397 0.373 0.024 3.62e-03 0.331 0.311 0.020 2.50e-01
GCSE PRScs.MultiPRS pT+clump.10FCVal 0.413 0.373 0.040 1.30e-02 0.346 0.311 0.035 8.04e-03
GCSE SBLUP.Inf pT+clump.10FCVal 0.400 0.373 0.027 6.62e-05 0.335 0.311 0.023 9.47e-02
GCSE lassosum.MultiPRS pT+clump.10FCVal 0.411 0.373 0.038 1.81e-02 0.347 0.311 0.036 7.92e-03
GCSE PRScs.10FCVal pT+clump.10FCVal 0.410 0.373 0.037 7.12e-10 0.341 0.311 0.029 2.29e-02
GCSE LDpred2.MultiPRS pT+clump.10FCVal 0.412 0.373 0.040 1.41e-02 0.339 0.311 0.028 4.78e-02
GCSE lassosum.PseudoVal pT+clump.10FCVal 0.321 0.373 -0.052 1.02e-06 0.276 0.311 -0.035 1.22e-01
GCSE LDpred2.PseudoVal pT+clump.10FCVal 0.406 0.373 0.033 5.80e-07 0.332 0.311 0.021 1.27e-01
GCSE LDpred1.MultiPRS pT+clump.10FCVal 0.409 0.373 0.036 2.56e-02 0.340 0.311 0.028 3.00e-02
GCSE pT+clump.10FCVal pT+clump.10FCVal 0.373 0.373 0.000 1.00e+00 0.311 0.311 0.000 1.00e+00
GCSE All.MultiPRS pT+clump.10FCVal 0.417 0.373 0.044 5.86e-03 0.347 0.311 0.035 3.75e-03
GCSE LDpred1.Inf pT+clump.10FCVal 0.408 0.373 0.035 1.52e-08 0.341 0.311 0.030 2.37e-02
GCSE DBSLMM.PseudoVal pT+clump.10FCVal 0.401 0.373 0.028 2.61e-05 0.337 0.311 0.026 7.14e-02
GCSE LDpred1.10FCVal pT+clump.10FCVal 0.402 0.373 0.029 1.56e-05 0.330 0.311 0.019 1.77e-01
GCSE lassosum.10FCVal pT+clump.10FCVal 0.407 0.373 0.034 3.87e-07 0.348 0.311 0.036 9.69e-03
GCSE PRScs.PseudoVal pT+clump.10FCVal 0.397 0.373 0.024 6.09e-04 0.351 0.311 0.040 8.58e-03
GCSE pT+clump.MultiPRS SBayesR.PseudoVal 0.381 0.397 -0.016 3.35e-01 0.328 0.331 -0.003 8.47e-01
GCSE LDpred1.10FCVal SBayesR.PseudoVal 0.402 0.397 0.005 4.08e-01 0.330 0.331 0.000 9.75e-01
GCSE PRScs.10FCVal SBayesR.PseudoVal 0.410 0.397 0.014 2.46e-02 0.341 0.331 0.010 4.56e-01
GCSE LDpred2.10FCVal SBayesR.PseudoVal 0.412 0.397 0.015 2.80e-03 0.342 0.331 0.011 2.89e-01
GCSE lassosum.PseudoVal SBayesR.PseudoVal 0.321 0.397 -0.076 2.14e-37 0.276 0.331 -0.055 1.49e-05
GCSE LDpred2.PseudoVal SBayesR.PseudoVal 0.406 0.397 0.009 1.48e-01 0.332 0.331 0.001 9.13e-01
GCSE lassosum.MultiPRS SBayesR.PseudoVal 0.411 0.397 0.015 3.63e-01 0.347 0.331 0.016 1.26e-01
GCSE LDpred2.MultiPRS SBayesR.PseudoVal 0.412 0.397 0.016 3.20e-01 0.339 0.331 0.008 4.36e-01
GCSE All.MultiPRS SBayesR.PseudoVal 0.417 0.397 0.021 1.96e-01 0.347 0.331 0.016 9.45e-02
GCSE PRScs.PseudoVal SBayesR.PseudoVal 0.397 0.397 0.001 8.33e-01 0.351 0.331 0.020 8.45e-03
GCSE LDpred1.MultiPRS SBayesR.PseudoVal 0.409 0.397 0.013 4.34e-01 0.340 0.331 0.009 4.97e-01
GCSE pT+clump.10FCVal SBayesR.PseudoVal 0.373 0.397 -0.024 3.62e-03 0.311 0.331 -0.020 2.50e-01
GCSE lassosum.10FCVal SBayesR.PseudoVal 0.407 0.397 0.011 1.91e-02 0.348 0.331 0.017 8.58e-02
GCSE SBayesR.PseudoVal SBayesR.PseudoVal 0.397 0.397 0.000 1.00e+00 0.331 0.331 0.000 1.00e+00
GCSE DBSLMM.PseudoVal SBayesR.PseudoVal 0.401 0.397 0.005 3.44e-01 0.337 0.331 0.006 5.72e-01
GCSE SBLUP.Inf SBayesR.PseudoVal 0.400 0.397 0.003 6.68e-01 0.335 0.331 0.004 7.99e-01
GCSE LDpred2.Inf SBayesR.PseudoVal 0.405 0.397 0.009 1.78e-01 0.331 0.331 0.000 9.91e-01
GCSE LDpred1.Inf SBayesR.PseudoVal 0.408 0.397 0.011 7.41e-02 0.341 0.331 0.010 4.47e-01
GCSE PRScs.MultiPRS SBayesR.PseudoVal 0.413 0.397 0.016 3.02e-01 0.346 0.331 0.015 1.59e-01
GCSE LDpred2.10FCVal SBLUP.Inf 0.412 0.400 0.012 4.75e-03 0.342 0.335 0.007 4.10e-01
GCSE PRScs.PseudoVal SBLUP.Inf 0.397 0.400 -0.002 6.98e-01 0.351 0.335 0.017 1.73e-01
GCSE LDpred1.10FCVal SBLUP.Inf 0.402 0.400 0.002 5.73e-01 0.330 0.335 -0.004 6.50e-01
GCSE LDpred2.Inf SBLUP.Inf 0.405 0.400 0.006 1.30e-01 0.331 0.335 -0.004 6.36e-01
GCSE SBayesR.PseudoVal SBLUP.Inf 0.397 0.400 -0.003 6.68e-01 0.331 0.335 -0.004 7.99e-01
GCSE lassosum.PseudoVal SBLUP.Inf 0.321 0.400 -0.079 3.28e-15 0.276 0.335 -0.059 5.25e-03
GCSE pT+clump.MultiPRS SBLUP.Inf 0.381 0.400 -0.019 2.51e-01 0.328 0.335 -0.006 6.38e-01
GCSE lassosum.MultiPRS SBLUP.Inf 0.411 0.400 0.012 4.70e-01 0.347 0.335 0.012 2.25e-01
GCSE PRScs.10FCVal SBLUP.Inf 0.410 0.400 0.011 5.14e-03 0.341 0.335 0.006 4.76e-01
GCSE PRScs.MultiPRS SBLUP.Inf 0.413 0.400 0.013 3.99e-01 0.346 0.335 0.011 1.98e-01
GCSE LDpred1.MultiPRS SBLUP.Inf 0.409 0.400 0.010 5.52e-01 0.340 0.335 0.005 4.80e-01
GCSE LDpred2.PseudoVal SBLUP.Inf 0.406 0.400 0.006 1.01e-01 0.332 0.335 -0.002 7.78e-01
GCSE LDpred1.Inf SBLUP.Inf 0.408 0.400 0.008 2.27e-02 0.341 0.335 0.006 4.01e-01
GCSE LDpred2.MultiPRS SBLUP.Inf 0.412 0.400 0.013 4.17e-01 0.339 0.335 0.004 6.48e-01
GCSE All.MultiPRS SBLUP.Inf 0.417 0.400 0.018 2.66e-01 0.347 0.335 0.012 1.47e-01
GCSE SBLUP.Inf SBLUP.Inf 0.400 0.400 0.000 1.00e+00 0.335 0.335 0.000 1.00e+00
GCSE DBSLMM.PseudoVal SBLUP.Inf 0.401 0.400 0.002 7.40e-01 0.337 0.335 0.002 8.41e-01
GCSE pT+clump.10FCVal SBLUP.Inf 0.373 0.400 -0.027 6.62e-05 0.311 0.335 -0.023 9.47e-02
GCSE lassosum.10FCVal SBLUP.Inf 0.407 0.400 0.008 1.14e-01 0.348 0.335 0.013 1.98e-01
ADHD LDpred2.PseudoVal All.MultiPRS 0.115 0.115 -0.001 9.76e-01 0.195 0.186 0.008 5.00e-01
ADHD pT+clump.10FCVal All.MultiPRS 0.094 0.115 -0.021 2.27e-01 0.150 0.186 -0.037 5.75e-02
ADHD LDpred2.MultiPRS All.MultiPRS 0.114 0.115 -0.001 9.60e-01 0.199 0.186 0.012 2.85e-01
ADHD PRScs.PseudoVal All.MultiPRS 0.109 0.115 -0.006 7.18e-01 0.189 0.186 0.003 8.36e-01
ADHD LDpred1.Inf All.MultiPRS 0.115 0.115 0.000 1.00e+00 0.191 0.186 0.005 6.83e-01
ADHD PRScs.MultiPRS All.MultiPRS 0.113 0.115 -0.002 8.86e-01 0.203 0.186 0.016 1.94e-01
ADHD LDpred2.Inf All.MultiPRS 0.115 0.115 0.000 9.98e-01 0.194 0.186 0.008 5.12e-01
ADHD lassosum.10FCVal All.MultiPRS 0.118 0.115 0.002 8.94e-01 0.194 0.186 0.007 5.38e-01
ADHD LDpred2.10FCVal All.MultiPRS 0.118 0.115 0.003 8.69e-01 0.198 0.186 0.012 2.97e-01
ADHD lassosum.MultiPRS All.MultiPRS 0.117 0.115 0.002 9.19e-01 0.199 0.186 0.012 1.92e-01
ADHD LDpred1.10FCVal All.MultiPRS 0.118 0.115 0.003 8.85e-01 0.190 0.186 0.004 7.38e-01
ADHD All.MultiPRS All.MultiPRS 0.115 0.115 0.000 1.00e+00 0.186 0.186 0.000 1.00e+00
ADHD SBayesR.PseudoVal All.MultiPRS 0.091 0.115 -0.024 1.69e-01 0.155 0.186 -0.031 1.12e-01
ADHD LDpred1.MultiPRS All.MultiPRS 0.117 0.115 0.002 9.21e-01 0.191 0.186 0.005 6.68e-01
ADHD pT+clump.MultiPRS All.MultiPRS 0.096 0.115 -0.019 2.64e-01 0.162 0.186 -0.025 1.61e-01
ADHD lassosum.PseudoVal All.MultiPRS 0.077 0.115 -0.039 2.75e-02 0.118 0.186 -0.068 2.13e-03
ADHD PRScs.10FCVal All.MultiPRS 0.114 0.115 -0.001 9.43e-01 0.207 0.186 0.021 1.15e-01
ADHD DBSLMM.PseudoVal All.MultiPRS 0.114 0.115 -0.001 9.46e-01 0.184 0.186 -0.003 8.33e-01
ADHD SBLUP.Inf All.MultiPRS 0.116 0.115 0.000 9.91e-01 0.193 0.186 0.007 5.81e-01
ADHD SBayesR.PseudoVal DBSLMM.PseudoVal 0.091 0.114 -0.023 2.17e-02 0.155 0.184 -0.028 1.54e-01
ADHD LDpred2.Inf DBSLMM.PseudoVal 0.115 0.114 0.001 8.29e-01 0.194 0.184 0.011 3.41e-01
ADHD pT+clump.10FCVal DBSLMM.PseudoVal 0.094 0.114 -0.020 3.55e-02 0.150 0.184 -0.034 6.94e-02
ADHD PRScs.10FCVal DBSLMM.PseudoVal 0.114 0.114 0.000 9.91e-01 0.207 0.184 0.024 4.81e-02
ADHD PRScs.PseudoVal DBSLMM.PseudoVal 0.109 0.114 -0.005 3.84e-01 0.189 0.184 0.006 6.32e-01
ADHD pT+clump.MultiPRS DBSLMM.PseudoVal 0.096 0.114 -0.018 3.01e-01 0.162 0.184 -0.022 1.60e-01
ADHD LDpred1.Inf DBSLMM.PseudoVal 0.115 0.114 0.001 8.35e-01 0.191 0.184 0.008 4.95e-01
ADHD lassosum.MultiPRS DBSLMM.PseudoVal 0.117 0.114 0.003 8.68e-01 0.199 0.184 0.015 1.42e-01
ADHD LDpred2.10FCVal DBSLMM.PseudoVal 0.118 0.114 0.004 4.45e-01 0.198 0.184 0.015 1.65e-01
ADHD lassosum.10FCVal DBSLMM.PseudoVal 0.118 0.114 0.004 6.04e-01 0.194 0.184 0.010 4.43e-01
ADHD LDpred1.10FCVal DBSLMM.PseudoVal 0.118 0.114 0.004 5.03e-01 0.190 0.184 0.007 5.46e-01
ADHD LDpred1.MultiPRS DBSLMM.PseudoVal 0.117 0.114 0.003 8.69e-01 0.191 0.184 0.008 4.78e-01
ADHD PRScs.MultiPRS DBSLMM.PseudoVal 0.113 0.114 -0.001 9.42e-01 0.203 0.184 0.019 1.04e-01
ADHD All.MultiPRS DBSLMM.PseudoVal 0.115 0.114 0.001 9.46e-01 0.186 0.184 0.003 8.33e-01
ADHD LDpred2.PseudoVal DBSLMM.PseudoVal 0.115 0.114 0.001 9.08e-01 0.195 0.184 0.011 3.20e-01
ADHD DBSLMM.PseudoVal DBSLMM.PseudoVal 0.114 0.114 0.000 1.00e+00 0.184 0.184 0.000 1.00e+00
ADHD LDpred2.MultiPRS DBSLMM.PseudoVal 0.114 0.114 0.000 9.85e-01 0.199 0.184 0.015 1.55e-01
ADHD lassosum.PseudoVal DBSLMM.PseudoVal 0.077 0.114 -0.038 7.96e-04 0.118 0.184 -0.065 2.85e-03
ADHD SBLUP.Inf DBSLMM.PseudoVal 0.116 0.114 0.001 8.13e-01 0.193 0.184 0.010 4.07e-01
ADHD SBayesR.PseudoVal lassosum.MultiPRS 0.091 0.117 -0.026 1.45e-01 0.155 0.199 -0.044 1.99e-02
ADHD LDpred2.10FCVal lassosum.MultiPRS 0.118 0.117 0.001 9.49e-01 0.198 0.199 0.000 9.51e-01
ADHD LDpred1.10FCVal lassosum.MultiPRS 0.118 0.117 0.001 9.65e-01 0.190 0.199 -0.008 2.73e-01
ADHD LDpred2.Inf lassosum.MultiPRS 0.115 0.117 -0.002 9.23e-01 0.194 0.199 -0.004 6.33e-01
ADHD PRScs.10FCVal lassosum.MultiPRS 0.114 0.117 -0.003 8.65e-01 0.207 0.199 0.009 3.60e-01
ADHD PRScs.MultiPRS lassosum.MultiPRS 0.113 0.117 -0.004 2.87e-01 0.203 0.199 0.004 6.24e-01
ADHD pT+clump.MultiPRS lassosum.MultiPRS 0.096 0.117 -0.021 2.29e-01 0.162 0.199 -0.037 1.07e-02
ADHD lassosum.MultiPRS lassosum.MultiPRS 0.117 0.117 0.000 1.00e+00 0.199 0.199 0.000 1.00e+00
ADHD lassosum.PseudoVal lassosum.MultiPRS 0.077 0.117 -0.041 2.23e-02 0.118 0.199 -0.081 1.23e-04
ADHD LDpred2.MultiPRS lassosum.MultiPRS 0.114 0.117 -0.003 4.95e-01 0.199 0.199 0.000 9.78e-01
ADHD LDpred1.MultiPRS lassosum.MultiPRS 0.117 0.117 0.000 9.91e-01 0.191 0.199 -0.007 3.44e-01
ADHD LDpred2.PseudoVal lassosum.MultiPRS 0.115 0.117 -0.002 8.97e-01 0.195 0.199 -0.004 6.79e-01
ADHD LDpred1.Inf lassosum.MultiPRS 0.115 0.117 -0.002 9.22e-01 0.191 0.199 -0.007 4.37e-01
ADHD pT+clump.10FCVal lassosum.MultiPRS 0.094 0.117 -0.023 1.95e-01 0.150 0.199 -0.049 3.02e-03
ADHD lassosum.10FCVal lassosum.MultiPRS 0.118 0.117 0.001 9.74e-01 0.194 0.199 -0.005 4.25e-01
ADHD SBLUP.Inf lassosum.MultiPRS 0.116 0.117 -0.002 9.30e-01 0.193 0.199 -0.006 5.12e-01
ADHD DBSLMM.PseudoVal lassosum.MultiPRS 0.114 0.117 -0.003 8.68e-01 0.184 0.199 -0.015 1.42e-01
ADHD All.MultiPRS lassosum.MultiPRS 0.115 0.117 -0.002 9.19e-01 0.186 0.199 -0.012 1.92e-01
ADHD PRScs.PseudoVal lassosum.MultiPRS 0.109 0.117 -0.008 6.49e-01 0.189 0.199 -0.010 2.76e-01
ADHD LDpred1.Inf lassosum.PseudoVal 0.115 0.077 0.039 1.84e-03 0.191 0.118 0.073 2.67e-03
ADHD PRScs.10FCVal lassosum.PseudoVal 0.114 0.077 0.038 3.37e-04 0.207 0.118 0.089 1.61e-05
ADHD LDpred2.MultiPRS lassosum.PseudoVal 0.114 0.077 0.038 3.25e-02 0.199 0.118 0.080 1.93e-04
ADHD lassosum.PseudoVal lassosum.PseudoVal 0.077 0.077 0.000 1.00e+00 0.118 0.118 0.000 1.00e+00
ADHD PRScs.PseudoVal lassosum.PseudoVal 0.109 0.077 0.032 2.04e-03 0.189 0.118 0.071 5.26e-04
ADHD DBSLMM.PseudoVal lassosum.PseudoVal 0.114 0.077 0.038 7.96e-04 0.184 0.118 0.065 2.85e-03
ADHD SBLUP.Inf lassosum.PseudoVal 0.116 0.077 0.039 1.86e-03 0.193 0.118 0.075 2.13e-03
ADHD LDpred2.Inf lassosum.PseudoVal 0.115 0.077 0.039 1.92e-03 0.194 0.118 0.076 1.88e-03
ADHD pT+clump.10FCVal lassosum.PseudoVal 0.094 0.077 0.017 1.94e-01 0.150 0.118 0.031 2.28e-01
ADHD LDpred2.10FCVal lassosum.PseudoVal 0.118 0.077 0.042 1.44e-04 0.198 0.118 0.080 1.91e-04
ADHD lassosum.MultiPRS lassosum.PseudoVal 0.117 0.077 0.041 2.23e-02 0.199 0.118 0.081 1.23e-04
ADHD LDpred1.10FCVal lassosum.PseudoVal 0.118 0.077 0.041 1.14e-04 0.190 0.118 0.072 6.39e-04
ADHD All.MultiPRS lassosum.PseudoVal 0.115 0.077 0.039 2.75e-02 0.186 0.118 0.068 2.13e-03
ADHD SBayesR.PseudoVal lassosum.PseudoVal 0.091 0.077 0.015 2.23e-01 0.155 0.118 0.037 1.22e-01
ADHD lassosum.10FCVal lassosum.PseudoVal 0.118 0.077 0.041 1.96e-04 0.194 0.118 0.076 5.33e-04
ADHD pT+clump.MultiPRS lassosum.PseudoVal 0.096 0.077 0.019 2.74e-01 0.162 0.118 0.044 6.43e-02
ADHD LDpred2.PseudoVal lassosum.PseudoVal 0.115 0.077 0.038 2.13e-03 0.195 0.118 0.077 1.69e-03
ADHD LDpred1.MultiPRS lassosum.PseudoVal 0.117 0.077 0.040 2.22e-02 0.191 0.118 0.073 7.86e-04
ADHD PRScs.MultiPRS lassosum.PseudoVal 0.113 0.077 0.036 4.09e-02 0.203 0.118 0.084 8.81e-05
ADHD lassosum.10FCVal lassosum.10FCVal 0.118 0.118 0.000 1.00e+00 0.194 0.194 0.000 1.00e+00
ADHD pT+clump.MultiPRS lassosum.10FCVal 0.096 0.118 -0.022 2.17e-01 0.162 0.194 -0.032 4.00e-02
ADHD LDpred2.Inf lassosum.10FCVal 0.115 0.118 -0.002 6.30e-01 0.194 0.194 0.001 9.48e-01
ADHD SBayesR.PseudoVal lassosum.10FCVal 0.091 0.118 -0.027 5.38e-03 0.155 0.194 -0.039 4.15e-02
ADHD PRScs.MultiPRS lassosum.10FCVal 0.113 0.118 -0.005 7.86e-01 0.203 0.194 0.009 2.65e-01
ADHD SBLUP.Inf lassosum.10FCVal 0.116 0.118 -0.002 6.31e-01 0.193 0.194 -0.001 9.39e-01
ADHD lassosum.MultiPRS lassosum.10FCVal 0.117 0.118 -0.001 9.74e-01 0.199 0.194 0.005 4.25e-01
ADHD PRScs.10FCVal lassosum.10FCVal 0.114 0.118 -0.004 4.53e-01 0.207 0.194 0.014 1.61e-01
ADHD LDpred2.MultiPRS lassosum.10FCVal 0.114 0.118 -0.003 8.57e-01 0.199 0.194 0.005 5.46e-01
ADHD PRScs.PseudoVal lassosum.10FCVal 0.109 0.118 -0.009 6.51e-02 0.189 0.194 -0.005 6.05e-01
ADHD LDpred2.PseudoVal lassosum.10FCVal 0.115 0.118 -0.003 5.68e-01 0.195 0.194 0.001 9.18e-01
ADHD LDpred1.MultiPRS lassosum.10FCVal 0.117 0.118 -0.001 9.72e-01 0.191 0.194 -0.002 7.65e-01
ADHD pT+clump.10FCVal lassosum.10FCVal 0.094 0.118 -0.024 2.94e-03 0.150 0.194 -0.044 5.36e-03
ADHD All.MultiPRS lassosum.10FCVal 0.115 0.118 -0.002 8.94e-01 0.186 0.194 -0.007 5.38e-01
ADHD LDpred1.Inf lassosum.10FCVal 0.115 0.118 -0.002 6.32e-01 0.191 0.194 -0.002 8.15e-01
ADHD DBSLMM.PseudoVal lassosum.10FCVal 0.114 0.118 -0.004 6.04e-01 0.184 0.194 -0.010 4.43e-01
ADHD LDpred1.10FCVal lassosum.10FCVal 0.118 0.118 0.000 9.56e-01 0.190 0.194 -0.003 6.56e-01
ADHD lassosum.PseudoVal lassosum.10FCVal 0.077 0.118 -0.041 1.96e-04 0.118 0.194 -0.076 5.33e-04
ADHD LDpred2.10FCVal lassosum.10FCVal 0.118 0.118 0.001 8.85e-01 0.198 0.194 0.005 5.65e-01
ADHD LDpred2.10FCVal LDpred1.MultiPRS 0.118 0.117 0.001 9.46e-01 0.198 0.191 0.007 9.43e-02
ADHD PRScs.PseudoVal LDpred1.MultiPRS 0.109 0.117 -0.008 6.49e-01 0.189 0.191 -0.002 7.43e-01
ADHD LDpred2.Inf LDpred1.MultiPRS 0.115 0.117 -0.002 9.25e-01 0.194 0.191 0.003 5.87e-01
ADHD pT+clump.10FCVal LDpred1.MultiPRS 0.094 0.117 -0.023 1.95e-01 0.150 0.191 -0.042 1.01e-02
ADHD SBayesR.PseudoVal LDpred1.MultiPRS 0.091 0.117 -0.026 1.44e-01 0.155 0.191 -0.036 5.87e-02
ADHD All.MultiPRS LDpred1.MultiPRS 0.115 0.117 -0.002 9.21e-01 0.186 0.191 -0.005 6.68e-01
ADHD LDpred1.10FCVal LDpred1.MultiPRS 0.118 0.117 0.001 9.62e-01 0.190 0.191 -0.001 3.69e-01
ADHD LDpred1.MultiPRS LDpred1.MultiPRS 0.117 0.117 0.000 1.00e+00 0.191 0.191 0.000 1.00e+00
ADHD PRScs.10FCVal LDpred1.MultiPRS 0.114 0.117 -0.003 8.66e-01 0.207 0.191 0.016 2.94e-02
ADHD lassosum.PseudoVal LDpred1.MultiPRS 0.077 0.117 -0.040 2.22e-02 0.118 0.191 -0.073 7.86e-04
ADHD pT+clump.MultiPRS LDpred1.MultiPRS 0.096 0.117 -0.021 2.30e-01 0.162 0.191 -0.030 5.96e-02
ADHD LDpred1.Inf LDpred1.MultiPRS 0.115 0.117 -0.002 9.23e-01 0.191 0.191 0.000 9.83e-01
ADHD lassosum.MultiPRS LDpred1.MultiPRS 0.117 0.117 0.000 9.91e-01 0.199 0.191 0.007 3.44e-01
ADHD PRScs.MultiPRS LDpred1.MultiPRS 0.113 0.117 -0.004 1.86e-01 0.203 0.191 0.011 7.52e-02
ADHD lassosum.10FCVal LDpred1.MultiPRS 0.118 0.117 0.001 9.72e-01 0.194 0.191 0.002 7.65e-01
ADHD LDpred2.PseudoVal LDpred1.MultiPRS 0.115 0.117 -0.002 8.99e-01 0.195 0.191 0.003 5.48e-01
ADHD DBSLMM.PseudoVal LDpred1.MultiPRS 0.114 0.117 -0.003 8.69e-01 0.184 0.191 -0.008 4.78e-01
ADHD LDpred2.MultiPRS LDpred1.MultiPRS 0.114 0.117 -0.003 2.06e-01 0.199 0.191 0.007 7.07e-02
ADHD SBLUP.Inf LDpred1.MultiPRS 0.116 0.117 -0.002 9.32e-01 0.193 0.191 0.002 7.46e-01
ADHD All.MultiPRS LDpred1.Inf 0.115 0.115 0.000 1.00e+00 0.186 0.191 -0.005 6.83e-01
ADHD LDpred2.PseudoVal LDpred1.Inf 0.115 0.115 -0.001 7.82e-01 0.195 0.191 0.003 4.09e-01
ADHD SBayesR.PseudoVal LDpred1.Inf 0.091 0.115 -0.024 1.53e-02 0.155 0.191 -0.036 7.16e-02
ADHD LDpred2.MultiPRS LDpred1.Inf 0.114 0.115 -0.001 9.61e-01 0.199 0.191 0.007 2.13e-01
ADHD PRScs.PseudoVal LDpred1.Inf 0.109 0.115 -0.006 1.63e-01 0.189 0.191 -0.002 7.88e-01
ADHD LDpred1.Inf LDpred1.Inf 0.115 0.115 0.000 1.00e+00 0.191 0.191 0.000 1.00e+00
ADHD pT+clump.10FCVal LDpred1.Inf 0.094 0.115 -0.021 8.52e-03 0.150 0.191 -0.042 9.67e-03
ADHD PRScs.MultiPRS LDpred1.Inf 0.113 0.115 -0.003 8.88e-01 0.203 0.191 0.011 1.59e-01
ADHD lassosum.PseudoVal LDpred1.Inf 0.077 0.115 -0.039 1.84e-03 0.118 0.191 -0.073 2.67e-03
ADHD pT+clump.MultiPRS LDpred1.Inf 0.096 0.115 -0.019 2.70e-01 0.162 0.191 -0.030 6.84e-02
ADHD LDpred1.MultiPRS LDpred1.Inf 0.117 0.115 0.002 9.23e-01 0.191 0.191 0.000 9.83e-01
ADHD PRScs.10FCVal LDpred1.Inf 0.114 0.115 -0.001 7.83e-01 0.207 0.191 0.016 8.31e-02
ADHD LDpred2.Inf LDpred1.Inf 0.115 0.115 0.000 9.83e-01 0.194 0.191 0.003 4.62e-01
ADHD SBLUP.Inf LDpred1.Inf 0.116 0.115 0.000 9.24e-01 0.193 0.191 0.002 6.92e-01
ADHD DBSLMM.PseudoVal LDpred1.Inf 0.114 0.115 -0.001 8.35e-01 0.184 0.191 -0.008 4.95e-01
ADHD lassosum.MultiPRS LDpred1.Inf 0.117 0.115 0.002 9.22e-01 0.199 0.191 0.007 4.37e-01
ADHD LDpred1.10FCVal LDpred1.Inf 0.118 0.115 0.003 3.81e-01 0.190 0.191 -0.001 8.32e-01
ADHD lassosum.10FCVal LDpred1.Inf 0.118 0.115 0.002 6.32e-01 0.194 0.191 0.002 8.15e-01
ADHD LDpred2.10FCVal LDpred1.Inf 0.118 0.115 0.003 3.30e-01 0.198 0.191 0.007 2.54e-01
ADHD LDpred1.Inf LDpred1.10FCVal 0.115 0.118 -0.003 3.81e-01 0.191 0.190 0.001 8.32e-01
ADHD PRScs.MultiPRS LDpred1.10FCVal 0.113 0.118 -0.005 7.77e-01 0.203 0.190 0.012 5.23e-02
ADHD LDpred1.10FCVal LDpred1.10FCVal 0.118 0.118 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
ADHD All.MultiPRS LDpred1.10FCVal 0.115 0.118 -0.003 8.85e-01 0.186 0.190 -0.004 7.38e-01
ADHD SBayesR.PseudoVal LDpred1.10FCVal 0.091 0.118 -0.027 4.67e-03 0.155 0.190 -0.035 6.47e-02
ADHD DBSLMM.PseudoVal LDpred1.10FCVal 0.114 0.118 -0.004 5.03e-01 0.184 0.190 -0.007 5.46e-01
ADHD pT+clump.MultiPRS LDpred1.10FCVal 0.096 0.118 -0.022 2.12e-01 0.162 0.190 -0.029 7.00e-02
ADHD lassosum.MultiPRS LDpred1.10FCVal 0.117 0.118 -0.001 9.65e-01 0.199 0.190 0.008 2.73e-01
ADHD PRScs.10FCVal LDpred1.10FCVal 0.114 0.118 -0.004 2.94e-01 0.207 0.190 0.017 1.79e-02
ADHD lassosum.10FCVal LDpred1.10FCVal 0.118 0.118 0.000 9.56e-01 0.194 0.190 0.003 6.56e-01
ADHD SBLUP.Inf LDpred1.10FCVal 0.116 0.118 -0.002 4.70e-01 0.193 0.190 0.003 6.49e-01
ADHD LDpred2.PseudoVal LDpred1.10FCVal 0.115 0.118 -0.003 3.59e-01 0.195 0.190 0.005 4.94e-01
ADHD pT+clump.10FCVal LDpred1.10FCVal 0.094 0.118 -0.024 4.01e-03 0.150 0.190 -0.041 1.34e-02
ADHD LDpred2.MultiPRS LDpred1.10FCVal 0.114 0.118 -0.003 8.47e-01 0.199 0.190 0.008 5.13e-02
ADHD PRScs.PseudoVal LDpred1.10FCVal 0.109 0.118 -0.009 1.30e-02 0.189 0.190 -0.001 8.60e-01
ADHD LDpred2.10FCVal LDpred1.10FCVal 0.118 0.118 0.000 8.73e-01 0.198 0.190 0.008 6.43e-02
ADHD LDpred1.MultiPRS LDpred1.10FCVal 0.117 0.118 -0.001 9.62e-01 0.191 0.190 0.001 3.69e-01
ADHD LDpred2.Inf LDpred1.10FCVal 0.115 0.118 -0.003 4.50e-01 0.194 0.190 0.004 5.24e-01
ADHD lassosum.PseudoVal LDpred1.10FCVal 0.077 0.118 -0.041 1.14e-04 0.118 0.190 -0.072 6.39e-04
ADHD LDpred1.Inf LDpred2.MultiPRS 0.115 0.114 0.001 9.61e-01 0.191 0.199 -0.007 2.13e-01
ADHD DBSLMM.PseudoVal LDpred2.MultiPRS 0.114 0.114 0.000 9.85e-01 0.184 0.199 -0.015 1.55e-01
ADHD SBLUP.Inf LDpred2.MultiPRS 0.116 0.114 0.001 9.52e-01 0.193 0.199 -0.005 2.77e-01
ADHD LDpred2.Inf LDpred2.MultiPRS 0.115 0.114 0.001 9.59e-01 0.194 0.199 -0.004 3.37e-01
ADHD pT+clump.10FCVal LDpred2.MultiPRS 0.094 0.114 -0.021 2.50e-01 0.150 0.199 -0.049 2.99e-03
ADHD LDpred2.10FCVal LDpred2.MultiPRS 0.118 0.114 0.004 8.32e-01 0.198 0.199 0.000 8.11e-01
ADHD PRScs.PseudoVal LDpred2.MultiPRS 0.109 0.114 -0.005 7.58e-01 0.189 0.199 -0.009 1.72e-01
ADHD LDpred1.10FCVal LDpred2.MultiPRS 0.118 0.114 0.003 8.47e-01 0.190 0.199 -0.008 5.13e-02
ADHD All.MultiPRS LDpred2.MultiPRS 0.115 0.114 0.001 9.60e-01 0.186 0.199 -0.012 2.85e-01
ADHD SBayesR.PseudoVal LDpred2.MultiPRS 0.091 0.114 -0.023 1.89e-01 0.155 0.199 -0.043 1.75e-02
ADHD lassosum.10FCVal LDpred2.MultiPRS 0.118 0.114 0.003 8.57e-01 0.194 0.199 -0.005 5.46e-01
ADHD pT+clump.MultiPRS LDpred2.MultiPRS 0.096 0.114 -0.019 2.92e-01 0.162 0.199 -0.037 1.98e-02
ADHD lassosum.MultiPRS LDpred2.MultiPRS 0.117 0.114 0.003 4.95e-01 0.199 0.199 0.000 9.78e-01
ADHD PRScs.10FCVal LDpred2.MultiPRS 0.114 0.114 0.000 9.82e-01 0.207 0.199 0.009 2.30e-01
ADHD PRScs.MultiPRS LDpred2.MultiPRS 0.113 0.114 -0.002 6.20e-01 0.203 0.199 0.004 5.34e-01
ADHD lassosum.PseudoVal LDpred2.MultiPRS 0.077 0.114 -0.038 3.25e-02 0.118 0.199 -0.080 1.93e-04
ADHD LDpred2.PseudoVal LDpred2.MultiPRS 0.115 0.114 0.000 9.85e-01 0.195 0.199 -0.004 4.14e-01
ADHD LDpred1.MultiPRS LDpred2.MultiPRS 0.117 0.114 0.003 2.06e-01 0.191 0.199 -0.007 7.07e-02
ADHD LDpred2.MultiPRS LDpred2.MultiPRS 0.114 0.114 0.000 1.00e+00 0.199 0.199 0.000 1.00e+00
ADHD LDpred1.Inf LDpred2.10FCVal 0.115 0.118 -0.003 3.30e-01 0.191 0.198 -0.007 2.54e-01
ADHD PRScs.MultiPRS LDpred2.10FCVal 0.113 0.118 -0.005 7.62e-01 0.203 0.198 0.004 5.11e-01
ADHD LDpred2.MultiPRS LDpred2.10FCVal 0.114 0.118 -0.004 8.32e-01 0.199 0.198 0.000 8.11e-01
ADHD PRScs.PseudoVal LDpred2.10FCVal 0.109 0.118 -0.009 1.19e-02 0.189 0.198 -0.009 1.86e-01
ADHD LDpred2.10FCVal LDpred2.10FCVal 0.118 0.118 0.000 1.00e+00 0.198 0.198 0.000 1.00e+00
ADHD lassosum.MultiPRS LDpred2.10FCVal 0.117 0.118 -0.001 9.49e-01 0.199 0.198 0.000 9.51e-01
ADHD LDpred1.10FCVal LDpred2.10FCVal 0.118 0.118 0.000 8.73e-01 0.190 0.198 -0.008 6.43e-02
ADHD All.MultiPRS LDpred2.10FCVal 0.115 0.118 -0.003 8.69e-01 0.186 0.198 -0.012 2.97e-01
ADHD SBayesR.PseudoVal LDpred2.10FCVal 0.091 0.118 -0.027 2.98e-03 0.155 0.198 -0.043 1.82e-02
ADHD DBSLMM.PseudoVal LDpred2.10FCVal 0.114 0.118 -0.004 4.45e-01 0.184 0.198 -0.015 1.65e-01
ADHD pT+clump.MultiPRS LDpred2.10FCVal 0.096 0.118 -0.022 2.05e-01 0.162 0.198 -0.037 2.06e-02
ADHD lassosum.PseudoVal LDpred2.10FCVal 0.077 0.118 -0.042 1.44e-04 0.118 0.198 -0.080 1.91e-04
ADHD PRScs.10FCVal LDpred2.10FCVal 0.114 0.118 -0.004 2.58e-01 0.207 0.198 0.009 2.22e-01
ADHD lassosum.10FCVal LDpred2.10FCVal 0.118 0.118 -0.001 8.85e-01 0.194 0.198 -0.005 5.65e-01
ADHD SBLUP.Inf LDpred2.10FCVal 0.116 0.118 -0.003 3.24e-01 0.193 0.198 -0.005 3.26e-01
ADHD LDpred2.PseudoVal LDpred2.10FCVal 0.115 0.118 -0.003 1.74e-01 0.195 0.198 -0.003 4.89e-01
ADHD pT+clump.10FCVal LDpred2.10FCVal 0.094 0.118 -0.024 3.71e-03 0.150 0.198 -0.049 3.13e-03
ADHD LDpred2.Inf LDpred2.10FCVal 0.115 0.118 -0.003 2.27e-01 0.194 0.198 -0.004 4.05e-01
ADHD LDpred1.MultiPRS LDpred2.10FCVal 0.117 0.118 -0.001 9.46e-01 0.191 0.198 -0.007 9.43e-02
ADHD lassosum.10FCVal LDpred2.PseudoVal 0.118 0.115 0.003 5.68e-01 0.194 0.195 -0.001 9.18e-01
ADHD SBLUP.Inf LDpred2.PseudoVal 0.116 0.115 0.001 7.02e-01 0.193 0.195 -0.002 6.52e-01
ADHD SBayesR.PseudoVal LDpred2.PseudoVal 0.091 0.115 -0.024 1.41e-02 0.155 0.195 -0.040 3.96e-02
ADHD All.MultiPRS LDpred2.PseudoVal 0.115 0.115 0.001 9.76e-01 0.186 0.195 -0.008 5.00e-01
ADHD PRScs.PseudoVal LDpred2.PseudoVal 0.109 0.115 -0.006 2.03e-01 0.189 0.195 -0.006 5.23e-01
ADHD lassosum.MultiPRS LDpred2.PseudoVal 0.117 0.115 0.002 8.97e-01 0.199 0.195 0.004 6.79e-01
ADHD PRScs.MultiPRS LDpred2.PseudoVal 0.113 0.115 -0.002 9.13e-01 0.203 0.195 0.008 3.50e-01
ADHD LDpred2.MultiPRS LDpred2.PseudoVal 0.114 0.115 0.000 9.85e-01 0.199 0.195 0.004 4.14e-01
ADHD PRScs.10FCVal LDpred2.PseudoVal 0.114 0.115 -0.001 8.74e-01 0.207 0.195 0.012 1.69e-01
ADHD LDpred2.PseudoVal LDpred2.PseudoVal 0.115 0.115 0.000 1.00e+00 0.195 0.195 0.000 1.00e+00
ADHD pT+clump.MultiPRS LDpred2.PseudoVal 0.096 0.115 -0.019 2.83e-01 0.162 0.195 -0.033 4.79e-02
ADHD pT+clump.10FCVal LDpred2.PseudoVal 0.094 0.115 -0.021 1.31e-02 0.150 0.195 -0.045 6.74e-03
ADHD lassosum.PseudoVal LDpred2.PseudoVal 0.077 0.115 -0.038 2.13e-03 0.118 0.195 -0.077 1.69e-03
ADHD LDpred1.Inf LDpred2.PseudoVal 0.115 0.115 0.001 7.82e-01 0.191 0.195 -0.003 4.09e-01
ADHD LDpred1.MultiPRS LDpred2.PseudoVal 0.117 0.115 0.002 8.99e-01 0.191 0.195 -0.003 5.48e-01
ADHD LDpred1.10FCVal LDpred2.PseudoVal 0.118 0.115 0.003 3.59e-01 0.190 0.195 -0.005 4.94e-01
ADHD LDpred2.Inf LDpred2.PseudoVal 0.115 0.115 0.001 5.56e-01 0.194 0.195 0.000 8.30e-01
ADHD LDpred2.10FCVal LDpred2.PseudoVal 0.118 0.115 0.003 1.74e-01 0.198 0.195 0.003 4.89e-01
ADHD DBSLMM.PseudoVal LDpred2.PseudoVal 0.114 0.115 -0.001 9.08e-01 0.184 0.195 -0.011 3.20e-01
ADHD pT+clump.MultiPRS LDpred2.Inf 0.096 0.115 -0.020 2.69e-01 0.162 0.194 -0.033 4.47e-02
ADHD lassosum.MultiPRS LDpred2.Inf 0.117 0.115 0.002 9.23e-01 0.199 0.194 0.004 6.33e-01
ADHD SBayesR.PseudoVal LDpred2.Inf 0.091 0.115 -0.024 1.22e-02 0.155 0.194 -0.039 4.21e-02
ADHD All.MultiPRS LDpred2.Inf 0.115 0.115 0.000 9.98e-01 0.186 0.194 -0.008 5.12e-01
ADHD SBLUP.Inf LDpred2.Inf 0.116 0.115 0.000 9.15e-01 0.193 0.194 -0.001 6.44e-01
ADHD LDpred2.PseudoVal LDpred2.Inf 0.115 0.115 -0.001 5.56e-01 0.195 0.194 0.000 8.30e-01
ADHD PRScs.MultiPRS LDpred2.Inf 0.113 0.115 -0.003 8.87e-01 0.203 0.194 0.008 2.97e-01
ADHD LDpred2.MultiPRS LDpred2.Inf 0.114 0.115 -0.001 9.59e-01 0.199 0.194 0.004 3.37e-01
ADHD PRScs.10FCVal LDpred2.Inf 0.114 0.115 -0.001 7.77e-01 0.207 0.194 0.013 1.60e-01
ADHD LDpred1.Inf LDpred2.Inf 0.115 0.115 0.000 9.83e-01 0.191 0.194 -0.003 4.62e-01
ADHD LDpred1.MultiPRS LDpred2.Inf 0.117 0.115 0.002 9.25e-01 0.191 0.194 -0.003 5.87e-01
ADHD pT+clump.10FCVal LDpred2.Inf 0.094 0.115 -0.021 8.33e-03 0.150 0.194 -0.045 5.40e-03
ADHD lassosum.PseudoVal LDpred2.Inf 0.077 0.115 -0.039 1.92e-03 0.118 0.194 -0.076 1.88e-03
ADHD PRScs.PseudoVal LDpred2.Inf 0.109 0.115 -0.006 1.62e-01 0.189 0.194 -0.005 5.52e-01
ADHD DBSLMM.PseudoVal LDpred2.Inf 0.114 0.115 -0.001 8.29e-01 0.184 0.194 -0.011 3.41e-01
ADHD LDpred1.10FCVal LDpred2.Inf 0.118 0.115 0.003 4.50e-01 0.190 0.194 -0.004 5.24e-01
ADHD LDpred2.Inf LDpred2.Inf 0.115 0.115 0.000 1.00e+00 0.194 0.194 0.000 1.00e+00
ADHD lassosum.10FCVal LDpred2.Inf 0.118 0.115 0.002 6.30e-01 0.194 0.194 -0.001 9.48e-01
ADHD LDpred2.10FCVal LDpred2.Inf 0.118 0.115 0.003 2.27e-01 0.198 0.194 0.004 4.05e-01
ADHD PRScs.10FCVal PRScs.MultiPRS 0.114 0.113 0.001 9.45e-01 0.207 0.203 0.005 2.25e-01
ADHD LDpred1.10FCVal PRScs.MultiPRS 0.118 0.113 0.005 7.77e-01 0.190 0.203 -0.012 5.23e-02
ADHD lassosum.MultiPRS PRScs.MultiPRS 0.117 0.113 0.004 2.87e-01 0.199 0.203 -0.004 6.24e-01
ADHD LDpred2.MultiPRS PRScs.MultiPRS 0.114 0.113 0.002 6.20e-01 0.199 0.203 -0.004 5.34e-01
ADHD All.MultiPRS PRScs.MultiPRS 0.115 0.113 0.002 8.86e-01 0.186 0.203 -0.016 1.94e-01
ADHD PRScs.PseudoVal PRScs.MultiPRS 0.109 0.113 -0.004 8.28e-01 0.189 0.203 -0.014 8.48e-02
ADHD LDpred1.MultiPRS PRScs.MultiPRS 0.117 0.113 0.004 1.86e-01 0.191 0.203 -0.011 7.52e-02
ADHD pT+clump.MultiPRS PRScs.MultiPRS 0.096 0.113 -0.017 3.36e-01 0.162 0.203 -0.041 6.55e-03
ADHD lassosum.PseudoVal PRScs.MultiPRS 0.077 0.113 -0.036 4.09e-02 0.118 0.203 -0.084 8.81e-05
ADHD SBayesR.PseudoVal PRScs.MultiPRS 0.091 0.113 -0.022 2.22e-01 0.155 0.203 -0.047 1.19e-02
ADHD DBSLMM.PseudoVal PRScs.MultiPRS 0.114 0.113 0.001 9.42e-01 0.184 0.203 -0.019 1.04e-01
ADHD SBLUP.Inf PRScs.MultiPRS 0.116 0.113 0.003 8.80e-01 0.193 0.203 -0.009 1.83e-01
ADHD LDpred2.Inf PRScs.MultiPRS 0.115 0.113 0.003 8.87e-01 0.194 0.203 -0.008 2.97e-01
ADHD pT+clump.10FCVal PRScs.MultiPRS 0.094 0.113 -0.019 2.90e-01 0.150 0.203 -0.053 6.43e-04
ADHD LDpred2.10FCVal PRScs.MultiPRS 0.118 0.113 0.005 7.62e-01 0.198 0.203 -0.004 5.11e-01
ADHD lassosum.10FCVal PRScs.MultiPRS 0.118 0.113 0.005 7.86e-01 0.194 0.203 -0.009 2.65e-01
ADHD LDpred2.PseudoVal PRScs.MultiPRS 0.115 0.113 0.002 9.13e-01 0.195 0.203 -0.008 3.50e-01
ADHD LDpred1.Inf PRScs.MultiPRS 0.115 0.113 0.003 8.88e-01 0.191 0.203 -0.011 1.59e-01
ADHD PRScs.MultiPRS PRScs.MultiPRS 0.113 0.113 0.000 1.00e+00 0.203 0.203 0.000 1.00e+00
ADHD LDpred2.PseudoVal PRScs.10FCVal 0.115 0.114 0.001 8.74e-01 0.195 0.207 -0.012 1.69e-01
ADHD PRScs.10FCVal PRScs.10FCVal 0.114 0.114 0.000 1.00e+00 0.207 0.207 0.000 1.00e+00
ADHD LDpred2.MultiPRS PRScs.10FCVal 0.114 0.114 0.000 9.82e-01 0.199 0.207 -0.009 2.30e-01
ADHD pT+clump.MultiPRS PRScs.10FCVal 0.096 0.114 -0.018 3.02e-01 0.162 0.207 -0.046 5.72e-03
ADHD LDpred1.Inf PRScs.10FCVal 0.115 0.114 0.001 7.83e-01 0.191 0.207 -0.016 8.31e-02
ADHD LDpred1.MultiPRS PRScs.10FCVal 0.117 0.114 0.003 8.66e-01 0.191 0.207 -0.016 2.94e-02
ADHD pT+clump.10FCVal PRScs.10FCVal 0.094 0.114 -0.020 2.32e-02 0.150 0.207 -0.058 8.98e-04
ADHD lassosum.PseudoVal PRScs.10FCVal 0.077 0.114 -0.038 3.37e-04 0.118 0.207 -0.089 1.61e-05
ADHD PRScs.PseudoVal PRScs.10FCVal 0.109 0.114 -0.005 2.31e-01 0.189 0.207 -0.018 2.78e-02
ADHD DBSLMM.PseudoVal PRScs.10FCVal 0.114 0.114 0.000 9.91e-01 0.184 0.207 -0.024 4.81e-02
ADHD SBLUP.Inf PRScs.10FCVal 0.116 0.114 0.001 7.52e-01 0.193 0.207 -0.014 1.14e-01
ADHD LDpred2.Inf PRScs.10FCVal 0.115 0.114 0.001 7.77e-01 0.194 0.207 -0.013 1.60e-01
ADHD lassosum.10FCVal PRScs.10FCVal 0.118 0.114 0.004 4.53e-01 0.194 0.207 -0.014 1.61e-01
ADHD LDpred2.10FCVal PRScs.10FCVal 0.118 0.114 0.004 2.58e-01 0.198 0.207 -0.009 2.22e-01
ADHD lassosum.MultiPRS PRScs.10FCVal 0.117 0.114 0.003 8.65e-01 0.199 0.207 -0.009 3.60e-01
ADHD LDpred1.10FCVal PRScs.10FCVal 0.118 0.114 0.004 2.94e-01 0.190 0.207 -0.017 1.79e-02
ADHD All.MultiPRS PRScs.10FCVal 0.115 0.114 0.001 9.43e-01 0.186 0.207 -0.021 1.15e-01
ADHD SBayesR.PseudoVal PRScs.10FCVal 0.091 0.114 -0.023 1.49e-02 0.155 0.207 -0.052 5.50e-03
ADHD PRScs.MultiPRS PRScs.10FCVal 0.113 0.114 -0.001 9.45e-01 0.203 0.207 -0.005 2.25e-01
ADHD All.MultiPRS PRScs.PseudoVal 0.115 0.109 0.006 7.18e-01 0.186 0.189 -0.003 8.36e-01
ADHD pT+clump.MultiPRS PRScs.PseudoVal 0.096 0.109 -0.013 4.58e-01 0.162 0.189 -0.027 9.13e-02
ADHD LDpred2.PseudoVal PRScs.PseudoVal 0.115 0.109 0.006 2.03e-01 0.195 0.189 0.006 5.23e-01
ADHD SBayesR.PseudoVal PRScs.PseudoVal 0.091 0.109 -0.018 5.71e-02 0.155 0.189 -0.034 7.14e-02
ADHD LDpred2.MultiPRS PRScs.PseudoVal 0.114 0.109 0.005 7.58e-01 0.199 0.189 0.009 1.72e-01
ADHD SBLUP.Inf PRScs.PseudoVal 0.116 0.109 0.007 1.50e-01 0.193 0.189 0.004 6.45e-01
ADHD LDpred1.Inf PRScs.PseudoVal 0.115 0.109 0.006 1.63e-01 0.191 0.189 0.002 7.88e-01
ADHD PRScs.10FCVal PRScs.PseudoVal 0.114 0.109 0.005 2.31e-01 0.207 0.189 0.018 2.78e-02
ADHD LDpred2.Inf PRScs.PseudoVal 0.115 0.109 0.006 1.62e-01 0.194 0.189 0.005 5.52e-01
ADHD PRScs.PseudoVal PRScs.PseudoVal 0.109 0.109 0.000 1.00e+00 0.189 0.189 0.000 1.00e+00
ADHD LDpred2.10FCVal PRScs.PseudoVal 0.118 0.109 0.009 1.19e-02 0.198 0.189 0.009 1.86e-01
ADHD pT+clump.10FCVal PRScs.PseudoVal 0.094 0.109 -0.015 8.48e-02 0.150 0.189 -0.040 2.15e-02
ADHD PRScs.MultiPRS PRScs.PseudoVal 0.113 0.109 0.004 8.28e-01 0.203 0.189 0.014 8.48e-02
ADHD lassosum.PseudoVal PRScs.PseudoVal 0.077 0.109 -0.032 2.04e-03 0.118 0.189 -0.071 5.26e-04
ADHD lassosum.10FCVal PRScs.PseudoVal 0.118 0.109 0.009 6.51e-02 0.194 0.189 0.005 6.05e-01
ADHD LDpred1.MultiPRS PRScs.PseudoVal 0.117 0.109 0.008 6.49e-01 0.191 0.189 0.002 7.43e-01
ADHD lassosum.MultiPRS PRScs.PseudoVal 0.117 0.109 0.008 6.49e-01 0.199 0.189 0.010 2.76e-01
ADHD LDpred1.10FCVal PRScs.PseudoVal 0.118 0.109 0.009 1.30e-02 0.190 0.189 0.001 8.60e-01
ADHD DBSLMM.PseudoVal PRScs.PseudoVal 0.114 0.109 0.005 3.84e-01 0.184 0.189 -0.006 6.32e-01
ADHD All.MultiPRS pT+clump.MultiPRS 0.115 0.096 0.019 2.64e-01 0.186 0.162 0.025 1.61e-01
ADHD SBayesR.PseudoVal pT+clump.MultiPRS 0.091 0.096 -0.005 7.87e-01 0.155 0.162 -0.006 7.69e-01
ADHD LDpred1.MultiPRS pT+clump.MultiPRS 0.117 0.096 0.021 2.30e-01 0.191 0.162 0.030 5.96e-02
ADHD pT+clump.MultiPRS pT+clump.MultiPRS 0.096 0.096 0.000 1.00e+00 0.162 0.162 0.000 1.00e+00
ADHD lassosum.PseudoVal pT+clump.MultiPRS 0.077 0.096 -0.019 2.74e-01 0.118 0.162 -0.044 6.43e-02
ADHD PRScs.10FCVal pT+clump.MultiPRS 0.114 0.096 0.018 3.02e-01 0.207 0.162 0.046 5.72e-03
ADHD DBSLMM.PseudoVal pT+clump.MultiPRS 0.114 0.096 0.018 3.01e-01 0.184 0.162 0.022 1.60e-01
ADHD SBLUP.Inf pT+clump.MultiPRS 0.116 0.096 0.020 2.65e-01 0.193 0.162 0.031 4.41e-02
ADHD LDpred2.Inf pT+clump.MultiPRS 0.115 0.096 0.020 2.69e-01 0.194 0.162 0.033 4.47e-02
ADHD pT+clump.10FCVal pT+clump.MultiPRS 0.094 0.096 -0.002 9.14e-01 0.150 0.162 -0.012 9.24e-02
ADHD LDpred2.10FCVal pT+clump.MultiPRS 0.118 0.096 0.022 2.05e-01 0.198 0.162 0.037 2.06e-02
ADHD PRScs.PseudoVal pT+clump.MultiPRS 0.109 0.096 0.013 4.58e-01 0.189 0.162 0.027 9.13e-02
ADHD LDpred1.10FCVal pT+clump.MultiPRS 0.118 0.096 0.022 2.12e-01 0.190 0.162 0.029 7.00e-02
ADHD LDpred1.Inf pT+clump.MultiPRS 0.115 0.096 0.019 2.70e-01 0.191 0.162 0.030 6.84e-02
ADHD PRScs.MultiPRS pT+clump.MultiPRS 0.113 0.096 0.017 3.36e-01 0.203 0.162 0.041 6.55e-03
ADHD lassosum.10FCVal pT+clump.MultiPRS 0.118 0.096 0.022 2.17e-01 0.194 0.162 0.032 4.00e-02
ADHD LDpred2.PseudoVal pT+clump.MultiPRS 0.115 0.096 0.019 2.83e-01 0.195 0.162 0.033 4.79e-02
ADHD lassosum.MultiPRS pT+clump.MultiPRS 0.117 0.096 0.021 2.29e-01 0.199 0.162 0.037 1.07e-02
ADHD LDpred2.MultiPRS pT+clump.MultiPRS 0.114 0.096 0.019 2.92e-01 0.199 0.162 0.037 1.98e-02
ADHD LDpred2.10FCVal pT+clump.10FCVal 0.118 0.094 0.024 3.71e-03 0.198 0.150 0.049 3.13e-03
ADHD pT+clump.MultiPRS pT+clump.10FCVal 0.096 0.094 0.002 9.14e-01 0.162 0.150 0.012 9.24e-02
ADHD LDpred2.Inf pT+clump.10FCVal 0.115 0.094 0.021 8.33e-03 0.194 0.150 0.045 5.40e-03
ADHD SBayesR.PseudoVal pT+clump.10FCVal 0.091 0.094 -0.003 8.12e-01 0.155 0.150 0.006 8.06e-01
ADHD PRScs.MultiPRS pT+clump.10FCVal 0.113 0.094 0.019 2.90e-01 0.203 0.150 0.053 6.43e-04
ADHD SBLUP.Inf pT+clump.10FCVal 0.116 0.094 0.022 5.10e-03 0.193 0.150 0.044 4.41e-03
ADHD lassosum.MultiPRS pT+clump.10FCVal 0.117 0.094 0.023 1.95e-01 0.199 0.150 0.049 3.02e-03
ADHD PRScs.10FCVal pT+clump.10FCVal 0.114 0.094 0.020 2.32e-02 0.207 0.150 0.058 8.98e-04
ADHD LDpred2.MultiPRS pT+clump.10FCVal 0.114 0.094 0.021 2.50e-01 0.199 0.150 0.049 2.99e-03
ADHD lassosum.10FCVal pT+clump.10FCVal 0.118 0.094 0.024 2.94e-03 0.194 0.150 0.044 5.36e-03
ADHD LDpred2.PseudoVal pT+clump.10FCVal 0.115 0.094 0.021 1.31e-02 0.195 0.150 0.045 6.74e-03
ADHD LDpred1.MultiPRS pT+clump.10FCVal 0.117 0.094 0.023 1.95e-01 0.191 0.150 0.042 1.01e-02
ADHD pT+clump.10FCVal pT+clump.10FCVal 0.094 0.094 0.000 1.00e+00 0.150 0.150 0.000 1.00e+00
ADHD All.MultiPRS pT+clump.10FCVal 0.115 0.094 0.021 2.27e-01 0.186 0.150 0.037 5.75e-02
ADHD LDpred1.Inf pT+clump.10FCVal 0.115 0.094 0.021 8.52e-03 0.191 0.150 0.042 9.67e-03
ADHD DBSLMM.PseudoVal pT+clump.10FCVal 0.114 0.094 0.020 3.55e-02 0.184 0.150 0.034 6.94e-02
ADHD LDpred1.10FCVal pT+clump.10FCVal 0.118 0.094 0.024 4.01e-03 0.190 0.150 0.041 1.34e-02
ADHD lassosum.PseudoVal pT+clump.10FCVal 0.077 0.094 -0.017 1.94e-01 0.118 0.150 -0.031 2.28e-01
ADHD PRScs.PseudoVal pT+clump.10FCVal 0.109 0.094 0.015 8.48e-02 0.189 0.150 0.040 2.15e-02
ADHD pT+clump.MultiPRS SBayesR.PseudoVal 0.096 0.091 0.005 7.87e-01 0.162 0.155 0.006 7.69e-01
ADHD LDpred1.10FCVal SBayesR.PseudoVal 0.118 0.091 0.027 4.67e-03 0.190 0.155 0.035 6.47e-02
ADHD PRScs.10FCVal SBayesR.PseudoVal 0.114 0.091 0.023 1.49e-02 0.207 0.155 0.052 5.50e-03
ADHD LDpred2.10FCVal SBayesR.PseudoVal 0.118 0.091 0.027 2.98e-03 0.198 0.155 0.043 1.82e-02
ADHD lassosum.10FCVal SBayesR.PseudoVal 0.118 0.091 0.027 5.38e-03 0.194 0.155 0.039 4.15e-02
ADHD LDpred2.PseudoVal SBayesR.PseudoVal 0.115 0.091 0.024 1.41e-02 0.195 0.155 0.040 3.96e-02
ADHD lassosum.MultiPRS SBayesR.PseudoVal 0.117 0.091 0.026 1.45e-01 0.199 0.155 0.044 1.99e-02
ADHD LDpred2.MultiPRS SBayesR.PseudoVal 0.114 0.091 0.023 1.89e-01 0.199 0.155 0.043 1.75e-02
ADHD All.MultiPRS SBayesR.PseudoVal 0.115 0.091 0.024 1.69e-01 0.186 0.155 0.031 1.12e-01
ADHD PRScs.PseudoVal SBayesR.PseudoVal 0.109 0.091 0.018 5.71e-02 0.189 0.155 0.034 7.14e-02
ADHD LDpred1.MultiPRS SBayesR.PseudoVal 0.117 0.091 0.026 1.44e-01 0.191 0.155 0.036 5.87e-02
ADHD pT+clump.10FCVal SBayesR.PseudoVal 0.094 0.091 0.003 8.12e-01 0.150 0.155 -0.006 8.06e-01
ADHD lassosum.PseudoVal SBayesR.PseudoVal 0.077 0.091 -0.015 2.23e-01 0.118 0.155 -0.037 1.22e-01
ADHD SBayesR.PseudoVal SBayesR.PseudoVal 0.091 0.091 0.000 1.00e+00 0.155 0.155 0.000 1.00e+00
ADHD DBSLMM.PseudoVal SBayesR.PseudoVal 0.114 0.091 0.023 2.17e-02 0.184 0.155 0.028 1.54e-01
ADHD SBLUP.Inf SBayesR.PseudoVal 0.116 0.091 0.024 1.18e-02 0.193 0.155 0.038 4.90e-02
ADHD LDpred2.Inf SBayesR.PseudoVal 0.115 0.091 0.024 1.22e-02 0.194 0.155 0.039 4.21e-02
ADHD LDpred1.Inf SBayesR.PseudoVal 0.115 0.091 0.024 1.53e-02 0.191 0.155 0.036 7.16e-02
ADHD PRScs.MultiPRS SBayesR.PseudoVal 0.113 0.091 0.022 2.22e-01 0.203 0.155 0.047 1.19e-02
ADHD LDpred2.10FCVal SBLUP.Inf 0.118 0.116 0.003 3.24e-01 0.198 0.193 0.005 3.26e-01
ADHD PRScs.PseudoVal SBLUP.Inf 0.109 0.116 -0.007 1.50e-01 0.189 0.193 -0.004 6.45e-01
ADHD LDpred1.10FCVal SBLUP.Inf 0.118 0.116 0.002 4.70e-01 0.190 0.193 -0.003 6.49e-01
ADHD LDpred2.Inf SBLUP.Inf 0.115 0.116 0.000 9.15e-01 0.194 0.193 0.001 6.44e-01
ADHD SBayesR.PseudoVal SBLUP.Inf 0.091 0.116 -0.024 1.18e-02 0.155 0.193 -0.038 4.90e-02
ADHD lassosum.10FCVal SBLUP.Inf 0.118 0.116 0.002 6.31e-01 0.194 0.193 0.001 9.39e-01
ADHD pT+clump.MultiPRS SBLUP.Inf 0.096 0.116 -0.020 2.65e-01 0.162 0.193 -0.031 4.41e-02
ADHD lassosum.MultiPRS SBLUP.Inf 0.117 0.116 0.002 9.30e-01 0.199 0.193 0.006 5.12e-01
ADHD PRScs.10FCVal SBLUP.Inf 0.114 0.116 -0.001 7.52e-01 0.207 0.193 0.014 1.14e-01
ADHD PRScs.MultiPRS SBLUP.Inf 0.113 0.116 -0.003 8.80e-01 0.203 0.193 0.009 1.83e-01
ADHD LDpred1.MultiPRS SBLUP.Inf 0.117 0.116 0.002 9.32e-01 0.191 0.193 -0.002 7.46e-01
ADHD LDpred2.PseudoVal SBLUP.Inf 0.115 0.116 -0.001 7.02e-01 0.195 0.193 0.002 6.52e-01
ADHD LDpred1.Inf SBLUP.Inf 0.115 0.116 0.000 9.24e-01 0.191 0.193 -0.002 6.92e-01
ADHD LDpred2.MultiPRS SBLUP.Inf 0.114 0.116 -0.001 9.52e-01 0.199 0.193 0.005 2.77e-01
ADHD All.MultiPRS SBLUP.Inf 0.115 0.116 0.000 9.91e-01 0.186 0.193 -0.007 5.81e-01
ADHD SBLUP.Inf SBLUP.Inf 0.116 0.116 0.000 1.00e+00 0.193 0.193 0.000 1.00e+00
ADHD DBSLMM.PseudoVal SBLUP.Inf 0.114 0.116 -0.001 8.13e-01 0.184 0.193 -0.010 4.07e-01
ADHD pT+clump.10FCVal SBLUP.Inf 0.094 0.116 -0.022 5.10e-03 0.150 0.193 -0.044 4.41e-03
ADHD lassosum.PseudoVal SBLUP.Inf 0.077 0.116 -0.039 1.86e-03 0.118 0.193 -0.075 2.13e-03

Show cross-validation differences between methods

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation differences between methods

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation


4.2 Using UK Biobank as reference

4.2.1 UKB

Show cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show UKBB results table

Correlation between PRS model predictions and observed values in UK Biobank
Phenotype Method Model CrossVal_R CrossVal_R_SE CrossVal_OR CrossVal_LowCI CrossVal_HighCI Cross_LiabR2 Cross_AUC CrossVal_pval IndepVal_R IndepVal_R_SE IndepVal_OR IndepVal_LowCI IndepVal_HighCI Indep_LiabR2 Indep_AUC IndepVal_pval
Depression All MultiPRS 0.144 0.005 1.343 1.316 1.370 0.025 0.582 2.11e-185 0.145 0.010 1.346 1.292 1.401 0.025 0.582 2.29e-48
Depression DBSLMM PseudoVal 0.139 0.005 1.329 1.302 1.356 0.023 0.579 7.64e-173 0.140 0.010 1.330 1.277 1.385 0.024 0.579 7.03e-45
Depression lassosum MultiPRS 0.143 0.005 1.339 1.312 1.366 0.025 0.581 6.56e-182 0.144 0.010 1.342 1.289 1.398 0.025 0.581 1.32e-47
Depression lassosum PseudoVal 0.079 0.005 1.172 1.149 1.196 0.007 0.545 2.78e-56 0.091 0.010 1.202 1.155 1.250 0.010 0.551 6.95e-20
Depression lassosum 10FCVal 0.143 0.005 1.338 1.311 1.365 0.025 0.581 5.29e-181 0.143 0.010 1.339 1.286 1.394 0.025 0.580 7.56e-47
Depression LDpred1 MultiPRS 0.142 0.005 1.337 1.310 1.364 0.024 0.581 8.03e-180 0.139 0.010 1.328 1.275 1.382 0.023 0.578 2.40e-44
Depression LDpred1 Inf 0.141 0.005 1.333 1.306 1.360 0.024 0.580 9.03e-177 0.137 0.010 1.321 1.269 1.375 0.022 0.577 7.76e-43
Depression LDpred1 10FCVal 0.142 0.005 1.336 1.310 1.364 0.024 0.581 7.71e-180 0.140 0.010 1.329 1.277 1.384 0.023 0.578 9.24e-45
Depression LDpred2 MultiPRS 0.144 0.005 1.341 1.315 1.369 0.025 0.582 2.76e-184 0.143 0.010 1.339 1.286 1.394 0.025 0.581 6.03e-47
Depression LDpred2 10FCVal 0.144 0.005 1.340 1.314 1.368 0.025 0.581 2.49e-183 0.140 0.010 1.330 1.278 1.385 0.024 0.579 6.24e-45
Depression LDpred2 PseudoVal 0.142 0.005 1.337 1.310 1.364 0.024 0.581 6.41e-180 0.140 0.010 1.330 1.277 1.385 0.024 0.579 6.69e-45
Depression LDpred2 Inf 0.141 0.005 1.333 1.307 1.360 0.024 0.580 5.06e-177 0.138 0.010 1.324 1.272 1.379 0.023 0.578 1.29e-43
Depression pT+clump MultiPRS 0.127 0.005 1.294 1.268 1.320 0.019 0.571 2.65e-143 0.130 0.010 1.303 1.251 1.356 0.020 0.573 5.91e-39
Depression pT+clump 10FCVal 0.120 0.005 1.277 1.251 1.303 0.017 0.568 3.52e-129 0.120 0.010 1.275 1.225 1.327 0.017 0.566 2.98e-33
Depression SBayesR PseudoVal 0.143 0.005 1.339 1.312 1.366 0.025 0.581 1.10e-181 0.143 0.010 1.337 1.284 1.392 0.024 0.581 1.57e-46
Depression SBLUP Inf 0.141 0.005 1.333 1.306 1.360 0.024 0.580 1.02e-176 0.137 0.010 1.323 1.271 1.377 0.023 0.578 2.36e-43
Intelligence All MultiPRS 0.102 0.005 NA NA NA NA NA 2.03e-93 0.097 0.010 NA NA NA NA NA 2.05e-22
Intelligence DBSLMM PseudoVal 0.090 0.005 NA NA NA NA NA 3.39e-73 0.082 0.010 NA NA NA NA NA 2.24e-16
Intelligence lassosum MultiPRS 0.102 0.005 NA NA NA NA NA 9.52e-93 0.099 0.010 NA NA NA NA NA 3.12e-23
Intelligence lassosum PseudoVal 0.064 0.005 NA NA NA NA NA 5.12e-38 0.055 0.010 NA NA NA NA NA 4.54e-08
Intelligence lassosum 10FCVal 0.098 0.005 NA NA NA NA NA 2.01e-86 0.096 0.010 NA NA NA NA NA 1.00e-21
Intelligence LDpred1 MultiPRS 0.101 0.005 NA NA NA NA NA 1.22e-90 0.094 0.010 NA NA NA NA NA 3.67e-21
Intelligence LDpred1 Inf 0.099 0.005 NA NA NA NA NA 5.96e-87 0.094 0.010 NA NA NA NA NA 6.76e-21
Intelligence LDpred1 10FCVal 0.100 0.005 NA NA NA NA NA 2.90e-90 0.094 0.010 NA NA NA NA NA 5.05e-21
Intelligence LDpred2 MultiPRS 0.103 0.005 NA NA NA NA NA 1.48e-94 0.098 0.010 NA NA NA NA NA 8.08e-23
Intelligence LDpred2 10FCVal 0.102 0.005 NA NA NA NA NA 1.71e-92 0.095 0.010 NA NA NA NA NA 1.06e-21
Intelligence LDpred2 PseudoVal 0.100 0.005 NA NA NA NA NA 6.34e-90 0.095 0.010 NA NA NA NA NA 1.33e-21
Intelligence LDpred2 Inf 0.099 0.005 NA NA NA NA NA 6.74e-88 0.094 0.010 NA NA NA NA NA 2.95e-21
Intelligence pT+clump MultiPRS 0.087 0.005 NA NA NA NA NA 1.74e-67 0.081 0.010 NA NA NA NA NA 3.56e-16
Intelligence pT+clump 10FCVal 0.084 0.005 NA NA NA NA NA 3.02e-63 0.074 0.010 NA NA NA NA NA 1.23e-13
Intelligence SBayesR PseudoVal 0.100 0.005 NA NA NA NA NA 3.08e-89 0.090 0.010 NA NA NA NA NA 1.67e-19
Intelligence SBLUP Inf 0.099 0.005 NA NA NA NA NA 5.34e-88 0.094 0.010 NA NA NA NA NA 6.50e-21
Height All MultiPRS 0.360 0.005 NA NA NA NA NA 0.00e+00 0.356 0.009 NA NA NA NA NA 5.44e-296
Height DBSLMM PseudoVal 0.333 0.005 NA NA NA NA NA 0.00e+00 0.324 0.009 NA NA NA NA NA 4.24e-243
Height lassosum MultiPRS 0.349 0.005 NA NA NA NA NA 0.00e+00 0.343 0.009 NA NA NA NA NA 5.60e-274
Height lassosum 10FCVal 0.347 0.005 NA NA NA NA NA 0.00e+00 0.340 0.009 NA NA NA NA NA 1.76e-268
Height lassosum PseudoVal 0.281 0.005 NA NA NA NA NA 0.00e+00 0.276 0.010 NA NA NA NA NA 6.42e-174
Height LDpred1 MultiPRS 0.304 0.005 NA NA NA NA NA 0.00e+00 0.303 0.010 NA NA NA NA NA 1.07e-210
Height LDpred1 Inf 0.297 0.005 NA NA NA NA NA 0.00e+00 0.295 0.010 NA NA NA NA NA 4.55e-200
Height LDpred1 10FCVal 0.287 0.005 NA NA NA NA NA 0.00e+00 0.288 0.010 NA NA NA NA NA 7.90e-191
Height LDpred2 MultiPRS 0.356 0.005 NA NA NA NA NA 0.00e+00 0.351 0.009 NA NA NA NA NA 1.32e-288
Height LDpred2 10FCVal 0.351 0.005 NA NA NA NA NA 0.00e+00 0.343 0.009 NA NA NA NA NA 1.02e-274
Height LDpred2 PseudoVal 0.335 0.005 NA NA NA NA NA 0.00e+00 0.326 0.009 NA NA NA NA NA 9.62e-247
Height LDpred2 Inf 0.302 0.005 NA NA NA NA NA 0.00e+00 0.299 0.010 NA NA NA NA NA 3.51e-206
Height pT+clump MultiPRS 0.320 0.005 NA NA NA NA NA 0.00e+00 0.314 0.009 NA NA NA NA NA 2.69e-227
Height pT+clump 10FCVal 0.305 0.005 NA NA NA NA NA 0.00e+00 0.299 0.010 NA NA NA NA NA 2.15e-205
Height SBayesR PseudoVal 0.342 0.005 NA NA NA NA NA 0.00e+00 0.335 0.009 NA NA NA NA NA 5.79e-261
Height SBLUP Inf 0.295 0.005 NA NA NA NA NA 0.00e+00 0.292 0.010 NA NA NA NA NA 1.00e-195
BMI All MultiPRS 0.308 0.005 NA NA NA NA NA 0.00e+00 0.308 0.010 NA NA NA NA NA 3.71e-219
BMI DBSLMM PseudoVal 0.283 0.005 NA NA NA NA NA 0.00e+00 0.283 0.010 NA NA NA NA NA 2.24e-183
BMI lassosum MultiPRS 0.305 0.005 NA NA NA NA NA 0.00e+00 0.308 0.010 NA NA NA NA NA 3.16e-218
BMI lassosum PseudoVal 0.211 0.005 NA NA NA NA NA 0.00e+00 0.220 0.010 NA NA NA NA NA 1.02e-109
BMI lassosum 10FCVal 0.300 0.005 NA NA NA NA NA 0.00e+00 0.300 0.010 NA NA NA NA NA 4.96e-207
BMI LDpred1 MultiPRS 0.286 0.005 NA NA NA NA NA 0.00e+00 0.282 0.010 NA NA NA NA NA 2.36e-182
BMI LDpred1 Inf 0.272 0.005 NA NA NA NA NA 0.00e+00 0.264 0.010 NA NA NA NA NA 8.31e-159
BMI LDpred1 10FCVal 0.277 0.005 NA NA NA NA NA 0.00e+00 0.273 0.010 NA NA NA NA NA 7.02e-170
BMI LDpred2 MultiPRS 0.305 0.005 NA NA NA NA NA 0.00e+00 0.303 0.010 NA NA NA NA NA 1.18e-211
BMI LDpred2 10FCVal 0.305 0.005 NA NA NA NA NA 0.00e+00 0.302 0.010 NA NA NA NA NA 5.91e-210
BMI LDpred2 PseudoVal 0.237 0.005 NA NA NA NA NA 0.00e+00 0.243 0.010 NA NA NA NA NA 3.13e-134
BMI LDpred2 Inf 0.293 0.005 NA NA NA NA NA 0.00e+00 0.287 0.010 NA NA NA NA NA 4.32e-189
BMI pT+clump MultiPRS 0.271 0.005 NA NA NA NA NA 0.00e+00 0.275 0.010 NA NA NA NA NA 3.53e-173
BMI pT+clump 10FCVal 0.248 0.005 NA NA NA NA NA 0.00e+00 0.245 0.010 NA NA NA NA NA 1.90e-136
BMI SBayesR PseudoVal 0.241 0.005 NA NA NA NA NA 0.00e+00 0.250 0.010 NA NA NA NA NA 3.61e-142
BMI SBLUP Inf 0.292 0.005 NA NA NA NA NA 0.00e+00 0.287 0.010 NA NA NA NA NA 3.03e-188
T2D All MultiPRS 0.243 0.005 1.706 1.668 1.744 0.062 0.650 0.00e+00 0.242 0.010 1.695 1.622 1.772 0.061 0.648 3.82e-133
T2D DBSLMM PseudoVal 0.230 0.005 1.659 1.622 1.696 0.056 0.643 0.00e+00 0.232 0.010 1.659 1.587 1.734 0.055 0.642 4.45e-122
T2D lassosum MultiPRS 0.239 0.005 1.693 1.656 1.731 0.060 0.648 0.00e+00 0.243 0.010 1.702 1.629 1.780 0.061 0.649 9.58e-135
T2D lassosum PseudoVal 0.203 0.005 1.559 1.525 1.593 0.043 0.625 0.00e+00 0.214 0.010 1.590 1.522 1.661 0.047 0.630 1.73e-103
T2D lassosum 10FCVal 0.213 0.005 1.595 1.560 1.631 0.047 0.631 0.00e+00 0.217 0.010 1.604 1.535 1.676 0.048 0.633 1.82e-106
T2D LDpred1 MultiPRS 0.230 0.005 1.659 1.622 1.696 0.056 0.643 0.00e+00 0.234 0.010 1.666 1.594 1.742 0.057 0.643 2.56e-124
T2D LDpred1 Inf 0.185 0.005 1.502 1.469 1.535 0.036 0.616 2.97e-306 0.181 0.010 1.482 1.419 1.547 0.033 0.612 1.86e-74
T2D LDpred1 10FCVal 0.224 0.005 1.636 1.600 1.673 0.053 0.639 0.00e+00 0.224 0.010 1.629 1.559 1.702 0.052 0.637 1.20e-113
T2D LDpred2 MultiPRS 0.241 0.005 1.700 1.662 1.738 0.061 0.649 0.00e+00 0.243 0.010 1.701 1.627 1.778 0.061 0.648 3.34e-134
T2D LDpred2 10FCVal 0.237 0.005 1.682 1.645 1.720 0.059 0.646 0.00e+00 0.239 0.010 1.684 1.611 1.760 0.059 0.646 1.27e-129
T2D LDpred2 PseudoVal 0.227 0.005 1.647 1.611 1.684 0.054 0.640 0.00e+00 0.229 0.010 1.650 1.578 1.724 0.054 0.640 1.41e-119
T2D LDpred2 Inf 0.189 0.005 1.512 1.479 1.546 0.037 0.618 5.36e-317 0.185 0.010 1.493 1.430 1.559 0.035 0.614 2.06e-77
T2D pT+clump MultiPRS 0.217 0.005 1.613 1.578 1.649 0.050 0.635 0.00e+00 0.221 0.010 1.621 1.551 1.694 0.050 0.636 4.64e-111
T2D pT+clump 10FCVal 0.170 0.005 1.451 1.420 1.483 0.030 0.606 2.62e-257 0.174 0.010 1.460 1.398 1.525 0.031 0.608 4.30e-69
T2D SBayesR PseudoVal 0.236 0.005 1.683 1.646 1.721 0.059 0.647 0.00e+00 0.236 0.010 1.673 1.601 1.749 0.057 0.645 2.02e-126
T2D SBLUP Inf 0.189 0.005 1.512 1.479 1.545 0.037 0.617 1.26e-316 0.183 0.010 1.489 1.426 1.555 0.034 0.613 2.23e-76
CAD All MultiPRS 0.190 0.005 1.482 1.452 1.513 0.027 0.609 1.19e-322 0.189 0.010 1.480 1.420 1.542 0.027 0.607 2.06e-81
CAD DBSLMM PseudoVal 0.169 0.005 1.416 1.387 1.445 0.021 0.597 1.43e-254 0.163 0.010 1.396 1.341 1.454 0.020 0.592 2.21e-60
CAD lassosum MultiPRS 0.187 0.005 1.470 1.440 1.501 0.026 0.606 4.28e-310 0.182 0.010 1.455 1.396 1.516 0.025 0.602 6.27e-75
CAD lassosum PseudoVal 0.162 0.005 1.394 1.366 1.423 0.020 0.592 1.10e-233 0.160 0.010 1.386 1.331 1.444 0.019 0.589 5.44e-58
CAD lassosum 10FCVal 0.174 0.005 1.432 1.403 1.461 0.023 0.599 1.23e-270 0.171 0.010 1.420 1.363 1.479 0.022 0.595 3.71e-66
CAD LDpred1 MultiPRS 0.173 0.005 1.426 1.397 1.456 0.022 0.598 8.75e-265 0.173 0.010 1.427 1.370 1.487 0.022 0.597 6.01e-68
CAD LDpred1 Inf 0.147 0.005 1.351 1.324 1.379 0.016 0.585 7.18e-193 0.148 0.010 1.353 1.299 1.408 0.016 0.584 5.94e-50
CAD LDpred1 10FCVal 0.172 0.005 1.423 1.394 1.453 0.022 0.598 4.09e-262 0.171 0.010 1.422 1.365 1.481 0.022 0.596 1.02e-66
CAD LDpred2 MultiPRS 0.190 0.005 1.480 1.450 1.511 0.027 0.608 1.32e-320 0.188 0.010 1.476 1.417 1.538 0.027 0.606 1.92e-80
CAD LDpred2 10FCVal 0.187 0.005 1.471 1.441 1.502 0.026 0.607 4.04e-311 0.184 0.010 1.462 1.403 1.524 0.025 0.604 7.28e-77
CAD LDpred2 PseudoVal 0.052 0.005 1.110 1.088 1.132 0.002 0.528 2.57e-25 0.060 0.010 1.127 1.084 1.173 0.003 0.531 2.24e-09
CAD LDpred2 Inf 0.161 0.005 1.390 1.362 1.419 0.019 0.592 8.05e-230 0.157 0.010 1.379 1.324 1.436 0.018 0.590 4.12e-56
CAD pT+clump MultiPRS 0.170 0.005 1.419 1.390 1.448 0.022 0.597 2.05e-257 0.166 0.010 1.406 1.350 1.464 0.020 0.593 1.35e-62
CAD pT+clump 10FCVal 0.139 0.005 1.326 1.300 1.353 0.014 0.578 6.44e-171 0.126 0.010 1.293 1.242 1.346 0.012 0.570 6.73e-37
CAD SBayesR PseudoVal 0.164 0.005 1.399 1.371 1.428 0.020 0.593 1.28e-238 0.170 0.010 1.418 1.361 1.477 0.022 0.595 1.14e-65
CAD SBLUP Inf 0.161 0.005 1.390 1.362 1.418 0.019 0.592 2.92e-229 0.156 0.010 1.376 1.321 1.433 0.018 0.589 1.75e-55
IBD All MultiPRS 0.146 0.005 1.560 1.513 1.610 0.049 0.644 3.68e-190 0.152 0.010 1.586 1.489 1.690 0.054 0.653 1.10e-52
IBD DBSLMM PseudoVal 0.130 0.005 1.500 1.453 1.548 0.039 0.631 7.76e-150 0.136 0.010 1.534 1.439 1.635 0.043 0.636 2.29e-42
IBD lassosum MultiPRS 0.144 0.005 1.550 1.502 1.599 0.048 0.641 1.99e-183 0.148 0.010 1.573 1.477 1.676 0.051 0.650 6.17e-50
IBD lassosum PseudoVal 0.133 0.005 1.515 1.468 1.563 0.041 0.633 1.07e-157 0.140 0.010 1.542 1.447 1.644 0.045 0.643 1.14e-44
IBD lassosum 10FCVal 0.134 0.005 1.517 1.470 1.566 0.042 0.632 4.55e-160 0.140 0.010 1.546 1.451 1.648 0.046 0.644 3.17e-45
IBD LDpred1 MultiPRS 0.130 0.005 1.516 1.468 1.566 0.039 0.629 1.53e-150 0.138 0.010 1.555 1.457 1.658 0.044 0.639 8.27e-44
IBD LDpred1 Inf 0.098 0.005 1.400 1.353 1.448 0.022 0.599 1.74e-86 0.103 0.010 1.423 1.329 1.523 0.024 0.603 5.46e-25
IBD LDpred1 10FCVal 0.129 0.005 1.502 1.455 1.551 0.038 0.628 1.94e-148 0.137 0.010 1.537 1.442 1.639 0.044 0.635 4.42e-43
IBD LDpred2 MultiPRS 0.143 0.005 1.550 1.502 1.599 0.047 0.642 6.23e-181 0.150 0.010 1.581 1.484 1.684 0.053 0.651 1.35e-51
IBD LDpred2 10FCVal 0.143 0.005 1.549 1.501 1.598 0.047 0.642 8.36e-182 0.149 0.010 1.576 1.479 1.678 0.052 0.651 7.24e-51
IBD LDpred2 PseudoVal 0.140 0.005 1.539 1.491 1.588 0.045 0.640 3.57e-174 0.145 0.010 1.561 1.465 1.663 0.049 0.649 2.45e-48
IBD LDpred2 Inf 0.096 0.005 1.390 1.343 1.438 0.021 0.597 1.45e-82 0.100 0.010 1.414 1.320 1.515 0.023 0.601 9.32e-24
IBD pT+clump MultiPRS 0.127 0.005 1.503 1.455 1.552 0.037 0.630 1.42e-144 0.136 0.010 1.544 1.447 1.647 0.043 0.634 1.70e-42
IBD pT+clump 10FCVal 0.111 0.005 1.445 1.398 1.494 0.028 0.616 7.90e-110 0.109 0.010 1.438 1.346 1.537 0.027 0.606 1.29e-27
IBD SBayesR PseudoVal 0.128 0.005 1.487 1.441 1.535 0.038 0.629 7.55e-145 0.143 0.010 1.547 1.453 1.647 0.048 0.647 4.88e-47
IBD SBLUP Inf 0.097 0.005 1.394 1.347 1.442 0.022 0.598 1.32e-84 0.102 0.010 1.421 1.327 1.521 0.024 0.601 1.35e-24
MultiScler All MultiPRS 0.135 0.005 1.557 1.501 1.616 0.081 0.722 7.93e-163 0.121 0.010 1.506 1.396 1.624 0.060 0.699 8.44e-34
MultiScler DBSLMM PseudoVal 0.091 0.005 1.426 1.370 1.485 0.037 0.665 7.49e-75 0.088 0.010 1.408 1.300 1.525 0.032 0.637 1.12e-18
MultiScler lassosum MultiPRS 0.128 0.005 1.542 1.483 1.603 0.072 0.712 4.17e-145 0.119 0.010 1.509 1.398 1.628 0.057 0.690 1.29e-32
MultiScler lassosum PseudoVal 0.103 0.005 1.453 1.397 1.510 0.047 0.692 1.28e-95 0.102 0.010 1.442 1.335 1.558 0.043 0.674 1.23e-24
MultiScler lassosum 10FCVal 0.115 0.005 1.520 1.460 1.582 0.059 0.679 2.36e-118 0.097 0.010 1.451 1.339 1.572 0.038 0.667 3.71e-22
MultiScler LDpred1 MultiPRS 0.112 0.005 1.533 1.471 1.596 0.056 0.685 1.73e-112 0.096 0.010 1.455 1.342 1.577 0.037 0.664 8.91e-22
MultiScler LDpred1 Inf 0.090 0.005 1.484 1.417 1.553 0.035 0.647 5.95e-72 0.078 0.010 1.435 1.308 1.573 0.025 0.627 4.26e-15
MultiScler LDpred1 10FCVal 0.107 0.005 1.495 1.436 1.557 0.051 0.681 7.79e-103 0.096 0.010 1.434 1.325 1.552 0.037 0.661 1.02e-21
MultiScler LDpred2 MultiPRS 0.133 0.005 1.549 1.492 1.607 0.078 0.721 1.36e-156 0.119 0.010 1.497 1.389 1.614 0.058 0.697 7.03e-33
MultiScler LDpred2 10FCVal 0.120 0.005 1.501 1.446 1.558 0.064 0.713 6.85e-129 0.108 0.010 1.460 1.353 1.576 0.047 0.686 3.31e-27
MultiScler LDpred2 PseudoVal 0.119 0.005 1.518 1.461 1.577 0.062 0.714 1.46e-125 0.110 0.010 1.475 1.366 1.593 0.050 0.692 1.64e-28
MultiScler LDpred2 Inf 0.094 0.005 1.501 1.435 1.571 0.039 0.646 3.59e-79 0.076 0.010 1.426 1.300 1.565 0.024 0.632 2.04e-14
MultiScler pT+clump MultiPRS 0.114 0.005 1.509 1.450 1.570 0.058 0.695 1.83e-116 0.108 0.010 1.500 1.386 1.624 0.048 0.678 1.73e-27
MultiScler pT+clump 10FCVal 0.090 0.005 1.444 1.384 1.506 0.036 0.665 4.63e-73 0.092 0.010 1.459 1.342 1.587 0.034 0.630 3.25e-20
MultiScler SBayesR PseudoVal 0.102 0.005 1.510 1.447 1.575 0.046 0.675 3.72e-92 0.083 0.010 1.426 1.307 1.555 0.028 0.640 9.20e-17
MultiScler SBLUP Inf 0.094 0.005 1.501 1.435 1.570 0.039 0.646 7.41e-79 0.076 0.010 1.422 1.296 1.561 0.023 0.630 3.58e-14
RheuArth All MultiPRS 0.182 0.005 1.643 1.596 1.692 0.063 0.669 1.61e-293 0.165 0.010 1.577 1.487 1.672 0.052 0.649 1.18e-61
RheuArth DBSLMM PseudoVal 0.157 0.005 1.542 1.498 1.588 0.047 0.652 8.55e-219 0.129 0.010 1.454 1.370 1.542 0.032 0.613 1.33e-38
RheuArth lassosum MultiPRS 0.169 0.005 1.592 1.546 1.640 0.054 0.661 7.29e-253 0.146 0.010 1.516 1.428 1.609 0.041 0.637 4.89e-49
RheuArth lassosum PseudoVal 0.127 0.005 1.491 1.444 1.539 0.030 0.619 4.78e-143 0.114 0.010 1.431 1.341 1.526 0.025 0.614 2.54e-30
RheuArth lassosum 10FCVal 0.162 0.005 1.564 1.519 1.610 0.050 0.655 2.75e-233 0.138 0.010 1.481 1.396 1.571 0.036 0.630 9.72e-44
RheuArth LDpred1 MultiPRS 0.144 0.005 1.534 1.488 1.582 0.039 0.642 1.14e-184 0.124 0.010 1.455 1.368 1.548 0.029 0.618 2.20e-35
RheuArth LDpred1 Inf 0.138 0.005 1.519 1.472 1.566 0.036 0.636 3.18e-170 0.114 0.010 1.423 1.337 1.516 0.024 0.611 3.41e-30
RheuArth LDpred1 10FCVal 0.141 0.005 1.518 1.472 1.565 0.038 0.639 1.68e-176 0.120 0.010 1.443 1.356 1.535 0.027 0.611 1.51e-33
RheuArth LDpred2 MultiPRS 0.156 0.005 1.582 1.534 1.630 0.046 0.649 7.20e-217 0.137 0.010 1.507 1.417 1.602 0.036 0.630 5.19e-43
RheuArth LDpred2 10FCVal 0.156 0.005 1.580 1.533 1.629 0.046 0.650 3.81e-217 0.138 0.010 1.509 1.420 1.604 0.036 0.631 7.81e-44
RheuArth LDpred2 PseudoVal 0.112 0.005 1.429 1.384 1.476 0.023 0.620 5.47e-111 0.111 0.010 1.431 1.341 1.527 0.023 0.610 9.20e-29
RheuArth LDpred2 Inf 0.087 0.005 1.360 1.313 1.408 0.014 0.589 4.32e-68 0.077 0.010 1.314 1.225 1.409 0.011 0.580 1.50e-14
RheuArth pT+clump MultiPRS 0.134 0.005 1.509 1.462 1.557 0.034 0.635 3.26e-160 0.125 0.010 1.470 1.381 1.565 0.030 0.623 3.50e-36
RheuArth pT+clump 10FCVal 0.113 0.005 1.437 1.391 1.483 0.024 0.617 1.64e-114 0.104 0.010 1.396 1.309 1.489 0.020 0.610 2.25e-25
RheuArth SBayesR PseudoVal 0.123 0.005 1.486 1.439 1.535 0.029 0.624 1.51e-135 0.123 0.010 1.484 1.391 1.583 0.029 0.617 3.39e-35
RheuArth SBLUP Inf 0.113 0.005 1.453 1.405 1.501 0.024 0.615 2.59e-114 0.101 0.010 1.400 1.310 1.497 0.019 0.601 4.25e-24
Prostate_Cancer All MultiPRS 0.185 0.005 1.641 1.594 1.690 0.170 0.700 7.81e-305 0.183 0.010 1.637 1.543 1.738 0.171 0.703 3.27e-76
Prostate_Cancer DBSLMM PseudoVal 0.179 0.005 1.645 1.596 1.696 0.159 0.691 5.07e-285 0.166 0.010 1.592 1.498 1.691 0.141 0.693 1.90e-62
Prostate_Cancer lassosum MultiPRS 0.188 0.005 1.686 1.635 1.738 0.174 0.700 6.60e-314 0.179 0.010 1.642 1.547 1.744 0.165 0.704 3.84e-73
Prostate_Cancer lassosum 10FCVal 0.182 0.005 1.665 1.615 1.716 0.164 0.694 1.18e-293 0.179 0.010 1.639 1.544 1.740 0.164 0.703 4.29e-73
Prostate_Cancer lassosum PseudoVal 0.169 0.005 1.633 1.584 1.684 0.142 0.683 1.32e-253 0.163 0.010 1.601 1.506 1.703 0.136 0.686 1.88e-60
Prostate_Cancer LDpred1 MultiPRS 0.165 0.005 1.615 1.565 1.666 0.135 0.680 2.27e-241 0.155 0.010 1.584 1.488 1.686 0.124 0.683 3.85e-55
Prostate_Cancer LDpred1 Inf 0.142 0.005 1.552 1.503 1.602 0.101 0.658 2.43e-179 0.133 0.010 1.528 1.432 1.630 0.092 0.656 6.33e-41
Prostate_Cancer LDpred1 10FCVal 0.159 0.005 1.590 1.542 1.640 0.126 0.675 3.36e-225 0.146 0.010 1.549 1.455 1.649 0.110 0.670 1.17e-48
Prostate_Cancer LDpred2 MultiPRS 0.191 0.005 1.669 1.620 1.720 0.180 0.704 0.00e+00 0.183 0.010 1.640 1.546 1.740 0.171 0.707 3.76e-76
Prostate_Cancer LDpred2 10FCVal 0.188 0.005 1.667 1.618 1.718 0.175 0.703 8.17e-316 0.187 0.010 1.656 1.561 1.756 0.178 0.712 3.46e-79
Prostate_Cancer LDpred2 PseudoVal 0.183 0.005 1.656 1.606 1.707 0.166 0.698 1.24e-297 0.184 0.010 1.655 1.560 1.757 0.174 0.709 2.83e-77
Prostate_Cancer LDpred2 Inf 0.136 0.005 1.536 1.487 1.586 0.093 0.651 1.30e-164 0.126 0.010 1.504 1.408 1.606 0.083 0.654 7.89e-37
Prostate_Cancer pT+clump MultiPRS 0.165 0.005 1.625 1.574 1.676 0.135 0.681 1.10e-241 0.173 0.010 1.654 1.554 1.761 0.153 0.692 8.75e-68
Prostate_Cancer pT+clump 10FCVal 0.150 0.005 1.580 1.531 1.632 0.112 0.666 6.18e-199 0.164 0.010 1.632 1.530 1.740 0.138 0.671 4.43e-61
Prostate_Cancer SBayesR PseudoVal 0.183 0.005 1.646 1.598 1.697 0.166 0.700 2.48e-298 0.182 0.010 1.629 1.536 1.728 0.169 0.705 2.69e-75
Prostate_Cancer SBLUP Inf 0.137 0.005 1.538 1.489 1.588 0.093 0.651 1.27e-165 0.125 0.010 1.500 1.404 1.602 0.081 0.652 3.52e-36
Breast_Cancer All MultiPRS 0.229 0.005 1.722 1.681 1.765 0.107 0.667 0.00e+00 0.214 0.010 1.652 1.574 1.733 0.090 0.654 5.88e-104
Breast_Cancer DBSLMM PseudoVal 0.216 0.005 1.675 1.635 1.717 0.095 0.659 0.00e+00 0.207 0.010 1.629 1.552 1.710 0.083 0.647 8.47e-97
Breast_Cancer lassosum MultiPRS 0.225 0.005 1.707 1.666 1.749 0.102 0.664 0.00e+00 0.209 0.010 1.633 1.556 1.714 0.085 0.651 1.18e-98
Breast_Cancer lassosum PseudoVal 0.216 0.005 1.679 1.638 1.721 0.095 0.657 0.00e+00 0.195 0.010 1.585 1.511 1.663 0.074 0.642 4.05e-86
Breast_Cancer lassosum 10FCVal 0.218 0.005 1.683 1.642 1.725 0.096 0.659 0.00e+00 0.196 0.010 1.591 1.517 1.670 0.075 0.643 2.16e-87
Breast_Cancer LDpred1 MultiPRS 0.217 0.005 1.678 1.638 1.720 0.096 0.660 0.00e+00 0.200 0.010 1.606 1.530 1.685 0.078 0.644 8.04e-91
Breast_Cancer LDpred1 Inf 0.172 0.005 1.523 1.486 1.562 0.060 0.627 1.28e-262 0.157 0.010 1.464 1.394 1.537 0.048 0.612 2.27e-56
Breast_Cancer LDpred1 10FCVal 0.204 0.005 1.630 1.590 1.670 0.084 0.650 0.00e+00 0.188 0.010 1.567 1.493 1.645 0.069 0.635 1.28e-80
Breast_Cancer LDpred2 MultiPRS 0.229 0.005 1.723 1.681 1.766 0.106 0.667 0.00e+00 0.213 0.010 1.648 1.570 1.729 0.089 0.654 1.02e-102
Breast_Cancer LDpred2 10FCVal 0.225 0.005 1.706 1.665 1.749 0.103 0.664 0.00e+00 0.208 0.010 1.629 1.553 1.709 0.085 0.650 4.03e-98
Breast_Cancer LDpred2 PseudoVal 0.223 0.005 1.701 1.660 1.744 0.101 0.662 0.00e+00 0.204 0.010 1.615 1.539 1.694 0.081 0.647 1.83e-94
Breast_Cancer LDpred2 Inf 0.168 0.005 1.509 1.473 1.547 0.057 0.625 7.16e-250 0.157 0.010 1.462 1.393 1.535 0.048 0.614 6.11e-56
Breast_Cancer pT+clump MultiPRS 0.201 0.005 1.627 1.588 1.668 0.082 0.648 0.00e+00 0.186 0.010 1.559 1.485 1.636 0.068 0.634 1.72e-78
Breast_Cancer pT+clump 10FCVal 0.182 0.005 1.561 1.523 1.600 0.067 0.633 1.38e-294 0.162 0.010 1.480 1.410 1.554 0.051 0.620 1.58e-59
Breast_Cancer SBayesR PseudoVal 0.227 0.005 1.712 1.671 1.755 0.104 0.664 0.00e+00 0.207 0.010 1.628 1.551 1.708 0.084 0.649 2.54e-97
Breast_Cancer SBLUP Inf 0.166 0.005 1.504 1.468 1.542 0.056 0.623 4.63e-245 0.154 0.010 1.455 1.386 1.527 0.046 0.611 2.73e-54

Show cross-validation results compared to pT+clump

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results compared to pT+clump

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show difference results table

Difference between methods in UKB with UKB reference
Phenotype Model 1 Test Model 2 Test Model 1 CrossVal R Model 2 CrossVal R CrossVal R Diff CrossVal R Diff P Model 1 IndepVal R Model 2 IndepVal R IndepVal R Diff IndepVal R Diff P
Depression lassosum.PseudoVal All.MultiPRS 0.079 0.144 -0.066 7.03e-21 0.091 0.145 -0.054 8.93e-09
Depression All.MultiPRS All.MultiPRS 0.144 0.144 0.000 1.00e+00 0.145 0.145 0.000 1.00e+00
Depression DBSLMM.PseudoVal All.MultiPRS 0.139 0.144 -0.005 4.75e-01 0.140 0.145 -0.005 3.89e-02
Depression LDpred1.Inf All.MultiPRS 0.141 0.144 -0.003 6.25e-01 0.137 0.145 -0.009 5.42e-04
Depression LDpred2.Inf All.MultiPRS 0.141 0.144 -0.003 6.35e-01 0.138 0.145 -0.008 1.49e-03
Depression lassosum.MultiPRS All.MultiPRS 0.143 0.144 -0.001 9.44e-02 0.144 0.145 -0.001 4.65e-01
Depression LDpred1.10FCVal All.MultiPRS 0.142 0.144 -0.002 7.54e-01 0.140 0.145 -0.006 4.36e-03
Depression pT+clump.MultiPRS All.MultiPRS 0.127 0.144 -0.018 1.17e-02 0.130 0.145 -0.015 1.43e-03
Depression LDpred2.MultiPRS All.MultiPRS 0.144 0.144 0.000 4.20e-01 0.143 0.145 -0.002 4.33e-02
Depression pT+clump.10FCVal All.MultiPRS 0.120 0.144 -0.024 6.04e-04 0.120 0.145 -0.026 1.64e-05
Depression lassosum.10FCVal All.MultiPRS 0.143 0.144 -0.002 8.04e-01 0.143 0.145 -0.002 2.47e-01
Depression LDpred2.10FCVal All.MultiPRS 0.144 0.144 -0.001 9.07e-01 0.140 0.145 -0.005 1.69e-03
Depression SBayesR.PseudoVal All.MultiPRS 0.143 0.144 -0.001 8.34e-01 0.143 0.145 -0.003 1.19e-01
Depression LDpred1.MultiPRS All.MultiPRS 0.142 0.144 -0.002 7.53e-01 0.139 0.145 -0.006 3.04e-03
Depression LDpred2.PseudoVal All.MultiPRS 0.142 0.144 -0.002 7.57e-01 0.140 0.145 -0.005 4.81e-03
Depression SBLUP.Inf All.MultiPRS 0.141 0.144 -0.003 6.23e-01 0.137 0.145 -0.008 7.74e-04
Depression LDpred2.MultiPRS DBSLMM.PseudoVal 0.144 0.139 0.005 5.14e-01 0.143 0.140 0.003 2.27e-01
Depression pT+clump.10FCVal DBSLMM.PseudoVal 0.120 0.139 -0.019 1.66e-09 0.120 0.140 -0.020 1.47e-03
Depression lassosum.PseudoVal DBSLMM.PseudoVal 0.079 0.139 -0.061 2.19e-36 0.091 0.140 -0.049 3.04e-07
Depression All.MultiPRS DBSLMM.PseudoVal 0.144 0.139 0.005 4.75e-01 0.145 0.140 0.005 3.89e-02
Depression LDpred1.MultiPRS DBSLMM.PseudoVal 0.142 0.139 0.003 6.88e-01 0.139 0.140 -0.001 7.61e-01
Depression LDpred2.PseudoVal DBSLMM.PseudoVal 0.142 0.139 0.003 3.89e-02 0.140 0.140 0.000 9.90e-01
Depression DBSLMM.PseudoVal DBSLMM.PseudoVal 0.139 0.139 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
Depression LDpred1.Inf DBSLMM.PseudoVal 0.141 0.139 0.002 2.82e-01 0.137 0.140 -0.003 2.62e-01
Depression LDpred2.Inf DBSLMM.PseudoVal 0.141 0.139 0.002 2.41e-01 0.138 0.140 -0.002 4.79e-01
Depression lassosum.MultiPRS DBSLMM.PseudoVal 0.143 0.139 0.004 6.04e-01 0.144 0.140 0.004 1.98e-01
Depression LDpred1.10FCVal DBSLMM.PseudoVal 0.142 0.139 0.003 4.34e-02 0.140 0.140 0.000 9.46e-01
Depression pT+clump.MultiPRS DBSLMM.PseudoVal 0.127 0.139 -0.013 7.35e-02 0.130 0.140 -0.010 7.09e-02
Depression SBayesR.PseudoVal DBSLMM.PseudoVal 0.143 0.139 0.004 2.39e-02 0.143 0.140 0.003 4.10e-01
Depression lassosum.10FCVal DBSLMM.PseudoVal 0.143 0.139 0.003 5.81e-02 0.143 0.140 0.003 3.77e-01
Depression LDpred2.10FCVal DBSLMM.PseudoVal 0.144 0.139 0.004 2.50e-03 0.140 0.140 0.000 9.76e-01
Depression SBLUP.Inf DBSLMM.PseudoVal 0.141 0.139 0.002 2.51e-01 0.137 0.140 -0.002 3.67e-01
Depression All.MultiPRS lassosum.MultiPRS 0.144 0.143 0.001 9.44e-02 0.145 0.144 0.001 4.65e-01
Depression LDpred1.MultiPRS lassosum.MultiPRS 0.142 0.143 -0.001 9.06e-01 0.139 0.144 -0.005 8.31e-02
Depression LDpred1.Inf lassosum.MultiPRS 0.141 0.143 -0.002 7.70e-01 0.137 0.144 -0.008 2.26e-02
Depression LDpred2.Inf lassosum.MultiPRS 0.141 0.143 -0.002 7.81e-01 0.138 0.144 -0.006 5.48e-02
Depression lassosum.MultiPRS lassosum.MultiPRS 0.143 0.143 0.000 1.00e+00 0.144 0.144 0.000 1.00e+00
Depression DBSLMM.PseudoVal lassosum.MultiPRS 0.139 0.143 -0.004 6.04e-01 0.140 0.144 -0.004 1.98e-01
Depression lassosum.PseudoVal lassosum.MultiPRS 0.079 0.143 -0.064 4.79e-20 0.091 0.144 -0.053 2.11e-08
Depression LDpred2.MultiPRS lassosum.MultiPRS 0.144 0.143 0.001 4.58e-01 0.143 0.144 -0.001 6.86e-01
Depression pT+clump.10FCVal lassosum.MultiPRS 0.120 0.143 -0.023 1.22e-03 0.120 0.144 -0.024 9.42e-05
Depression lassosum.10FCVal lassosum.MultiPRS 0.143 0.143 0.000 9.59e-01 0.143 0.144 -0.001 3.04e-01
Depression LDpred2.10FCVal lassosum.MultiPRS 0.144 0.143 0.001 9.36e-01 0.140 0.144 -0.004 1.40e-01
Depression SBayesR.PseudoVal lassosum.MultiPRS 0.143 0.143 0.000 9.90e-01 0.143 0.144 -0.002 5.50e-01
Depression LDpred2.PseudoVal lassosum.MultiPRS 0.142 0.143 -0.001 9.10e-01 0.140 0.144 -0.004 1.48e-01
Depression SBLUP.Inf lassosum.MultiPRS 0.141 0.143 -0.002 7.68e-01 0.137 0.144 -0.007 3.29e-02
Depression pT+clump.MultiPRS lassosum.MultiPRS 0.127 0.143 -0.016 2.02e-02 0.130 0.144 -0.014 6.06e-03
Depression LDpred1.10FCVal lassosum.MultiPRS 0.142 0.143 -0.001 9.07e-01 0.140 0.144 -0.005 1.15e-01
Depression All.MultiPRS lassosum.PseudoVal 0.144 0.079 0.066 7.03e-21 0.145 0.091 0.054 8.93e-09
Depression LDpred1.MultiPRS lassosum.PseudoVal 0.142 0.079 0.063 1.28e-19 0.139 0.091 0.048 5.29e-06
Depression LDpred2.PseudoVal lassosum.PseudoVal 0.142 0.079 0.063 9.31e-32 0.140 0.091 0.049 4.87e-06
Depression DBSLMM.PseudoVal lassosum.PseudoVal 0.139 0.079 0.061 2.19e-36 0.140 0.091 0.049 3.04e-07
Depression LDpred1.Inf lassosum.PseudoVal 0.141 0.079 0.062 4.87e-30 0.137 0.091 0.045 2.48e-05
Depression LDpred2.Inf lassosum.PseudoVal 0.141 0.079 0.062 2.32e-29 0.138 0.091 0.047 1.93e-05
Depression lassosum.MultiPRS lassosum.PseudoVal 0.143 0.079 0.064 4.79e-20 0.144 0.091 0.053 2.11e-08
Depression LDpred1.10FCVal lassosum.PseudoVal 0.142 0.079 0.063 3.14e-33 0.140 0.091 0.049 3.13e-06
Depression lassosum.PseudoVal lassosum.PseudoVal 0.079 0.079 0.000 1.00e+00 0.091 0.091 0.000 1.00e+00
Depression LDpred2.MultiPRS lassosum.PseudoVal 0.144 0.079 0.065 1.28e-20 0.143 0.091 0.052 4.31e-08
Depression pT+clump.10FCVal lassosum.PseudoVal 0.120 0.079 0.042 2.09e-12 0.120 0.091 0.029 1.52e-02
Depression lassosum.10FCVal lassosum.PseudoVal 0.143 0.079 0.064 3.03e-34 0.143 0.091 0.052 5.18e-07
Depression LDpred2.10FCVal lassosum.PseudoVal 0.144 0.079 0.065 1.06e-34 0.140 0.091 0.049 2.64e-06
Depression SBayesR.PseudoVal lassosum.PseudoVal 0.143 0.079 0.064 5.91e-40 0.143 0.091 0.051 7.65e-08
Depression SBLUP.Inf lassosum.PseudoVal 0.141 0.079 0.062 8.45e-30 0.137 0.091 0.046 1.92e-05
Depression pT+clump.MultiPRS lassosum.PseudoVal 0.127 0.079 0.048 7.44e-12 0.130 0.091 0.039 1.21e-04
Depression All.MultiPRS lassosum.10FCVal 0.144 0.143 0.002 8.04e-01 0.145 0.143 0.002 2.47e-01
Depression LDpred1.MultiPRS lassosum.10FCVal 0.142 0.143 0.000 9.46e-01 0.139 0.143 -0.004 1.68e-01
Depression LDpred1.Inf lassosum.10FCVal 0.141 0.143 -0.002 2.86e-01 0.137 0.143 -0.006 4.44e-02
Depression LDpred2.Inf lassosum.10FCVal 0.141 0.143 -0.002 2.90e-01 0.138 0.143 -0.005 8.94e-02
Depression lassosum.MultiPRS lassosum.10FCVal 0.143 0.143 0.000 9.59e-01 0.144 0.143 0.001 3.04e-01
Depression DBSLMM.PseudoVal lassosum.10FCVal 0.139 0.143 -0.003 5.81e-02 0.140 0.143 -0.003 3.77e-01
Depression lassosum.PseudoVal lassosum.10FCVal 0.079 0.143 -0.064 3.03e-34 0.091 0.143 -0.052 5.18e-07
Depression LDpred2.MultiPRS lassosum.10FCVal 0.144 0.143 0.001 8.53e-01 0.143 0.143 0.000 9.58e-01
Depression pT+clump.10FCVal lassosum.10FCVal 0.120 0.143 -0.022 6.57e-14 0.120 0.143 -0.023 9.26e-05
Depression lassosum.10FCVal lassosum.10FCVal 0.143 0.143 0.000 1.00e+00 0.143 0.143 0.000 1.00e+00
Depression LDpred2.10FCVal lassosum.10FCVal 0.144 0.143 0.001 5.15e-01 0.140 0.143 -0.003 2.89e-01
Depression SBayesR.PseudoVal lassosum.10FCVal 0.143 0.143 0.000 8.61e-01 0.143 0.143 0.000 8.73e-01
Depression LDpred2.PseudoVal lassosum.10FCVal 0.142 0.143 0.000 7.51e-01 0.140 0.143 -0.003 2.61e-01
Depression SBLUP.Inf lassosum.10FCVal 0.141 0.143 -0.002 2.43e-01 0.137 0.143 -0.006 6.04e-02
Depression pT+clump.MultiPRS lassosum.10FCVal 0.127 0.143 -0.016 2.40e-02 0.130 0.143 -0.013 1.29e-02
Depression LDpred1.10FCVal lassosum.10FCVal 0.142 0.143 0.000 7.35e-01 0.140 0.143 -0.003 2.33e-01
Depression DBSLMM.PseudoVal LDpred1.MultiPRS 0.139 0.142 -0.003 6.88e-01 0.140 0.139 0.001 7.61e-01
Depression LDpred2.MultiPRS LDpred1.MultiPRS 0.144 0.142 0.002 8.01e-01 0.143 0.139 0.004 4.38e-02
Depression pT+clump.10FCVal LDpred1.MultiPRS 0.120 0.142 -0.022 1.76e-03 0.120 0.139 -0.019 1.36e-03
Depression lassosum.10FCVal LDpred1.MultiPRS 0.143 0.142 0.000 9.46e-01 0.143 0.139 0.004 1.68e-01
Depression lassosum.PseudoVal LDpred1.MultiPRS 0.079 0.142 -0.063 1.28e-19 0.091 0.139 -0.048 5.29e-06
Depression All.MultiPRS LDpred1.MultiPRS 0.144 0.142 0.002 7.53e-01 0.145 0.139 0.006 3.04e-03
Depression LDpred1.MultiPRS LDpred1.MultiPRS 0.142 0.142 0.000 1.00e+00 0.139 0.139 0.000 1.00e+00
Depression LDpred2.PseudoVal LDpred1.MultiPRS 0.142 0.142 0.000 9.96e-01 0.140 0.139 0.001 5.40e-01
Depression SBLUP.Inf LDpred1.MultiPRS 0.141 0.142 -0.001 8.59e-01 0.137 0.139 -0.002 2.66e-01
Depression LDpred1.Inf LDpred1.MultiPRS 0.141 0.142 -0.001 8.61e-01 0.137 0.139 -0.002 5.76e-02
Depression LDpred2.Inf LDpred1.MultiPRS 0.141 0.142 -0.001 8.73e-01 0.138 0.139 -0.001 4.58e-01
Depression lassosum.MultiPRS LDpred1.MultiPRS 0.143 0.142 0.001 9.06e-01 0.144 0.139 0.005 8.31e-02
Depression LDpred1.10FCVal LDpred1.MultiPRS 0.142 0.142 0.000 9.99e-01 0.140 0.139 0.001 4.73e-01
Depression pT+clump.MultiPRS LDpred1.MultiPRS 0.127 0.142 -0.015 2.79e-02 0.130 0.139 -0.009 9.53e-02
Depression SBayesR.PseudoVal LDpred1.MultiPRS 0.143 0.142 0.001 9.16e-01 0.143 0.139 0.003 1.55e-01
Depression LDpred2.10FCVal LDpred1.MultiPRS 0.144 0.142 0.001 8.42e-01 0.140 0.139 0.001 5.51e-01
Depression All.MultiPRS LDpred1.Inf 0.144 0.141 0.003 6.25e-01 0.145 0.137 0.009 5.42e-04
Depression LDpred1.Inf LDpred1.Inf 0.141 0.141 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
Depression LDpred2.Inf LDpred1.Inf 0.141 0.141 0.000 8.86e-01 0.138 0.137 0.001 3.68e-01
Depression DBSLMM.PseudoVal LDpred1.Inf 0.139 0.141 -0.002 2.82e-01 0.140 0.137 0.003 2.62e-01
Depression lassosum.PseudoVal LDpred1.Inf 0.079 0.141 -0.062 4.87e-30 0.091 0.137 -0.045 2.48e-05
Depression LDpred2.MultiPRS LDpred1.Inf 0.144 0.141 0.003 6.70e-01 0.143 0.137 0.007 5.34e-03
Depression pT+clump.10FCVal LDpred1.Inf 0.120 0.141 -0.021 9.10e-12 0.120 0.137 -0.017 5.54e-03
Depression lassosum.10FCVal LDpred1.Inf 0.143 0.141 0.002 2.86e-01 0.143 0.137 0.006 4.44e-02
Depression LDpred2.10FCVal LDpred1.Inf 0.144 0.141 0.003 1.27e-03 0.140 0.137 0.003 3.73e-02
Depression SBayesR.PseudoVal LDpred1.Inf 0.143 0.141 0.002 1.78e-01 0.143 0.137 0.006 3.98e-02
Depression LDpred1.MultiPRS LDpred1.Inf 0.142 0.141 0.001 8.61e-01 0.139 0.137 0.002 5.76e-02
Depression LDpred2.PseudoVal LDpred1.Inf 0.142 0.141 0.001 9.68e-02 0.140 0.137 0.003 2.78e-02
Depression SBLUP.Inf LDpred1.Inf 0.141 0.141 0.000 9.73e-01 0.137 0.137 0.001 5.14e-01
Depression pT+clump.MultiPRS LDpred1.Inf 0.127 0.141 -0.014 4.37e-02 0.130 0.137 -0.007 2.44e-01
Depression lassosum.MultiPRS LDpred1.Inf 0.143 0.141 0.002 7.70e-01 0.144 0.137 0.008 2.26e-02
Depression LDpred1.10FCVal LDpred1.Inf 0.142 0.141 0.001 1.07e-01 0.140 0.137 0.003 4.00e-02
Depression LDpred1.Inf LDpred1.10FCVal 0.141 0.142 -0.001 1.07e-01 0.137 0.140 -0.003 4.00e-02
Depression DBSLMM.PseudoVal LDpred1.10FCVal 0.139 0.142 -0.003 4.34e-02 0.140 0.140 0.000 9.46e-01
Depression lassosum.PseudoVal LDpred1.10FCVal 0.079 0.142 -0.063 3.14e-33 0.091 0.140 -0.049 3.13e-06
Depression LDpred2.MultiPRS LDpred1.10FCVal 0.144 0.142 0.002 8.02e-01 0.143 0.140 0.003 7.03e-02
Depression pT+clump.10FCVal LDpred1.10FCVal 0.120 0.142 -0.022 3.04e-13 0.120 0.140 -0.020 8.98e-04
Depression lassosum.10FCVal LDpred1.10FCVal 0.143 0.142 0.000 7.35e-01 0.143 0.140 0.003 2.33e-01
Depression LDpred2.10FCVal LDpred1.10FCVal 0.144 0.142 0.001 6.98e-02 0.140 0.140 0.000 8.60e-01
Depression All.MultiPRS LDpred1.10FCVal 0.144 0.142 0.002 7.54e-01 0.145 0.140 0.006 4.36e-03
Depression LDpred1.MultiPRS LDpred1.10FCVal 0.142 0.142 0.000 9.99e-01 0.139 0.140 -0.001 4.73e-01
Depression LDpred2.PseudoVal LDpred1.10FCVal 0.142 0.142 0.000 9.64e-01 0.140 0.140 0.000 8.75e-01
Depression SBLUP.Inf LDpred1.10FCVal 0.141 0.142 -0.001 1.08e-01 0.137 0.140 -0.002 1.43e-01
Depression pT+clump.MultiPRS LDpred1.10FCVal 0.127 0.142 -0.015 2.84e-02 0.130 0.140 -0.010 6.95e-02
Depression LDpred2.Inf LDpred1.10FCVal 0.141 0.142 -0.001 1.74e-01 0.138 0.140 -0.002 2.66e-01
Depression lassosum.MultiPRS LDpred1.10FCVal 0.143 0.142 0.001 9.07e-01 0.144 0.140 0.005 1.15e-01
Depression LDpred1.10FCVal LDpred1.10FCVal 0.142 0.142 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
Depression SBayesR.PseudoVal LDpred1.10FCVal 0.143 0.142 0.001 5.10e-01 0.143 0.140 0.003 2.09e-01
Depression LDpred2.MultiPRS LDpred2.MultiPRS 0.144 0.144 0.000 1.00e+00 0.143 0.143 0.000 1.00e+00
Depression lassosum.PseudoVal LDpred2.MultiPRS 0.079 0.144 -0.065 1.28e-20 0.091 0.143 -0.052 4.31e-08
Depression All.MultiPRS LDpred2.MultiPRS 0.144 0.144 0.000 4.20e-01 0.145 0.143 0.002 4.33e-02
Depression LDpred1.MultiPRS LDpred2.MultiPRS 0.142 0.144 -0.002 8.01e-01 0.139 0.143 -0.004 4.38e-02
Depression DBSLMM.PseudoVal LDpred2.MultiPRS 0.139 0.144 -0.005 5.14e-01 0.140 0.143 -0.003 2.27e-01
Depression LDpred1.Inf LDpred2.MultiPRS 0.141 0.144 -0.003 6.70e-01 0.137 0.143 -0.007 5.34e-03
Depression LDpred2.Inf LDpred2.MultiPRS 0.141 0.144 -0.003 6.81e-01 0.138 0.143 -0.005 1.20e-02
Depression lassosum.MultiPRS LDpred2.MultiPRS 0.143 0.144 -0.001 4.58e-01 0.144 0.143 0.001 6.86e-01
Depression LDpred1.10FCVal LDpred2.MultiPRS 0.142 0.144 -0.002 8.02e-01 0.140 0.143 -0.003 7.03e-02
Depression pT+clump.MultiPRS LDpred2.MultiPRS 0.127 0.144 -0.017 1.40e-02 0.130 0.143 -0.013 1.36e-02
Depression SBayesR.PseudoVal LDpred2.MultiPRS 0.143 0.144 -0.001 8.84e-01 0.143 0.143 -0.001 7.11e-01
Depression pT+clump.10FCVal LDpred2.MultiPRS 0.120 0.144 -0.024 7.60e-04 0.120 0.143 -0.023 2.53e-04
Depression lassosum.10FCVal LDpred2.MultiPRS 0.143 0.144 -0.001 8.53e-01 0.143 0.143 0.000 9.58e-01
Depression LDpred2.10FCVal LDpred2.MultiPRS 0.144 0.144 0.000 9.57e-01 0.140 0.143 -0.003 1.08e-02
Depression LDpred2.PseudoVal LDpred2.MultiPRS 0.142 0.144 -0.002 8.05e-01 0.140 0.143 -0.003 5.72e-02
Depression SBLUP.Inf LDpred2.MultiPRS 0.141 0.144 -0.003 6.68e-01 0.137 0.143 -0.006 9.31e-03
Depression LDpred2.MultiPRS LDpred2.10FCVal 0.144 0.144 0.000 9.57e-01 0.143 0.140 0.003 1.08e-02
Depression pT+clump.10FCVal LDpred2.10FCVal 0.120 0.144 -0.023 5.02e-14 0.120 0.140 -0.020 1.11e-03
Depression lassosum.PseudoVal LDpred2.10FCVal 0.079 0.144 -0.065 1.06e-34 0.091 0.140 -0.049 2.64e-06
Depression All.MultiPRS LDpred2.10FCVal 0.144 0.144 0.001 9.07e-01 0.145 0.140 0.005 1.69e-03
Depression LDpred1.MultiPRS LDpred2.10FCVal 0.142 0.144 -0.001 8.42e-01 0.139 0.140 -0.001 5.51e-01
Depression LDpred2.PseudoVal LDpred2.10FCVal 0.142 0.144 -0.001 1.76e-03 0.140 0.140 0.000 9.56e-01
Depression DBSLMM.PseudoVal LDpred2.10FCVal 0.139 0.144 -0.004 2.50e-03 0.140 0.140 0.000 9.76e-01
Depression LDpred1.Inf LDpred2.10FCVal 0.141 0.144 -0.003 1.27e-03 0.137 0.140 -0.003 3.73e-02
Depression LDpred2.Inf LDpred2.10FCVal 0.141 0.144 -0.002 6.49e-06 0.138 0.140 -0.002 5.88e-02
Depression lassosum.MultiPRS LDpred2.10FCVal 0.143 0.144 -0.001 9.36e-01 0.144 0.140 0.004 1.40e-01
Depression LDpred1.10FCVal LDpred2.10FCVal 0.142 0.144 -0.001 6.98e-02 0.140 0.140 0.000 8.60e-01
Depression pT+clump.MultiPRS LDpred2.10FCVal 0.127 0.144 -0.017 1.69e-02 0.130 0.140 -0.010 7.15e-02
Depression SBayesR.PseudoVal LDpred2.10FCVal 0.143 0.144 -0.001 5.79e-01 0.143 0.140 0.003 2.78e-01
Depression lassosum.10FCVal LDpred2.10FCVal 0.143 0.144 -0.001 5.15e-01 0.143 0.140 0.003 2.89e-01
Depression LDpred2.10FCVal LDpred2.10FCVal 0.144 0.144 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
Depression SBLUP.Inf LDpred2.10FCVal 0.141 0.144 -0.003 5.14e-05 0.137 0.140 -0.003 5.09e-02
Depression LDpred2.MultiPRS LDpred2.PseudoVal 0.144 0.142 0.002 8.05e-01 0.143 0.140 0.003 5.72e-02
Depression lassosum.PseudoVal LDpred2.PseudoVal 0.079 0.142 -0.063 9.31e-32 0.091 0.140 -0.049 4.87e-06
Depression All.MultiPRS LDpred2.PseudoVal 0.144 0.142 0.002 7.57e-01 0.145 0.140 0.005 4.81e-03
Depression LDpred1.MultiPRS LDpred2.PseudoVal 0.142 0.142 0.000 9.96e-01 0.139 0.140 -0.001 5.40e-01
Depression DBSLMM.PseudoVal LDpred2.PseudoVal 0.139 0.142 -0.003 3.89e-02 0.140 0.140 0.000 9.90e-01
Depression LDpred1.Inf LDpred2.PseudoVal 0.141 0.142 -0.001 9.68e-02 0.137 0.140 -0.003 2.78e-02
Depression LDpred2.Inf LDpred2.PseudoVal 0.141 0.142 -0.001 5.10e-05 0.138 0.140 -0.002 3.18e-04
Depression lassosum.MultiPRS LDpred2.PseudoVal 0.143 0.142 0.001 9.10e-01 0.144 0.140 0.004 1.48e-01
Depression LDpred1.10FCVal LDpred2.PseudoVal 0.142 0.142 0.000 9.64e-01 0.140 0.140 0.000 8.75e-01
Depression pT+clump.MultiPRS LDpred2.PseudoVal 0.127 0.142 -0.015 2.81e-02 0.130 0.140 -0.010 6.71e-02
Depression SBayesR.PseudoVal LDpred2.PseudoVal 0.143 0.142 0.001 5.70e-01 0.143 0.140 0.003 2.92e-01
Depression pT+clump.10FCVal LDpred2.PseudoVal 0.120 0.142 -0.022 1.48e-13 0.120 0.140 -0.020 6.85e-04
Depression lassosum.10FCVal LDpred2.PseudoVal 0.143 0.142 0.000 7.51e-01 0.143 0.140 0.003 2.61e-01
Depression LDpred2.10FCVal LDpred2.PseudoVal 0.144 0.142 0.001 1.76e-03 0.140 0.140 0.000 9.56e-01
Depression LDpred2.PseudoVal LDpred2.PseudoVal 0.142 0.142 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
Depression SBLUP.Inf LDpred2.PseudoVal 0.141 0.142 -0.001 1.64e-02 0.137 0.140 -0.003 1.92e-02
Depression DBSLMM.PseudoVal LDpred2.Inf 0.139 0.141 -0.002 2.41e-01 0.140 0.138 0.002 4.79e-01
Depression LDpred2.MultiPRS LDpred2.Inf 0.144 0.141 0.003 6.81e-01 0.143 0.138 0.005 1.20e-02
Depression pT+clump.10FCVal LDpred2.Inf 0.120 0.141 -0.021 3.74e-12 0.120 0.138 -0.018 2.51e-03
Depression lassosum.10FCVal LDpred2.Inf 0.143 0.141 0.002 2.90e-01 0.143 0.138 0.005 8.94e-02
Depression lassosum.PseudoVal LDpred2.Inf 0.079 0.141 -0.062 2.32e-29 0.091 0.138 -0.047 1.93e-05
Depression All.MultiPRS LDpred2.Inf 0.144 0.141 0.003 6.35e-01 0.145 0.138 0.008 1.49e-03
Depression LDpred1.MultiPRS LDpred2.Inf 0.142 0.141 0.001 8.73e-01 0.139 0.138 0.001 4.58e-01
Depression LDpred2.PseudoVal LDpred2.Inf 0.142 0.141 0.001 5.10e-05 0.140 0.138 0.002 3.18e-04
Depression SBLUP.Inf LDpred2.Inf 0.141 0.141 0.000 7.79e-01 0.137 0.138 0.000 6.24e-01
Depression LDpred1.Inf LDpred2.Inf 0.141 0.141 0.000 8.86e-01 0.137 0.138 -0.001 3.68e-01
Depression LDpred2.Inf LDpred2.Inf 0.141 0.141 0.000 1.00e+00 0.138 0.138 0.000 1.00e+00
Depression lassosum.MultiPRS LDpred2.Inf 0.143 0.141 0.002 7.81e-01 0.144 0.138 0.006 5.48e-02
Depression LDpred1.10FCVal LDpred2.Inf 0.142 0.141 0.001 1.74e-01 0.140 0.138 0.002 2.66e-01
Depression pT+clump.MultiPRS LDpred2.Inf 0.127 0.141 -0.014 4.22e-02 0.130 0.138 -0.008 1.63e-01
Depression SBayesR.PseudoVal LDpred2.Inf 0.143 0.141 0.002 2.00e-01 0.143 0.138 0.005 1.07e-01
Depression LDpred2.10FCVal LDpred2.Inf 0.144 0.141 0.002 6.49e-06 0.140 0.138 0.002 5.88e-02
Depression All.MultiPRS pT+clump.MultiPRS 0.144 0.127 0.018 1.17e-02 0.145 0.130 0.015 1.43e-03
Depression LDpred1.MultiPRS pT+clump.MultiPRS 0.142 0.127 0.015 2.79e-02 0.139 0.130 0.009 9.53e-02
Depression LDpred2.PseudoVal pT+clump.MultiPRS 0.142 0.127 0.015 2.81e-02 0.140 0.130 0.010 6.71e-02
Depression DBSLMM.PseudoVal pT+clump.MultiPRS 0.139 0.127 0.013 7.35e-02 0.140 0.130 0.010 7.09e-02
Depression LDpred1.Inf pT+clump.MultiPRS 0.141 0.127 0.014 4.37e-02 0.137 0.130 0.007 2.44e-01
Depression LDpred2.Inf pT+clump.MultiPRS 0.141 0.127 0.014 4.22e-02 0.138 0.130 0.008 1.63e-01
Depression lassosum.MultiPRS pT+clump.MultiPRS 0.143 0.127 0.016 2.02e-02 0.144 0.130 0.014 6.06e-03
Depression LDpred1.10FCVal pT+clump.MultiPRS 0.142 0.127 0.015 2.84e-02 0.140 0.130 0.010 6.95e-02
Depression lassosum.PseudoVal pT+clump.MultiPRS 0.079 0.127 -0.048 7.44e-12 0.091 0.130 -0.039 1.21e-04
Depression LDpred2.MultiPRS pT+clump.MultiPRS 0.144 0.127 0.017 1.40e-02 0.143 0.130 0.013 1.36e-02
Depression pT+clump.10FCVal pT+clump.MultiPRS 0.120 0.127 -0.006 3.56e-01 0.120 0.130 -0.010 5.91e-04
Depression lassosum.10FCVal pT+clump.MultiPRS 0.143 0.127 0.016 2.40e-02 0.143 0.130 0.013 1.29e-02
Depression LDpred2.10FCVal pT+clump.MultiPRS 0.144 0.127 0.017 1.69e-02 0.140 0.130 0.010 7.15e-02
Depression SBayesR.PseudoVal pT+clump.MultiPRS 0.143 0.127 0.016 2.18e-02 0.143 0.130 0.013 1.43e-02
Depression SBLUP.Inf pT+clump.MultiPRS 0.141 0.127 0.014 4.40e-02 0.137 0.130 0.007 1.82e-01
Depression pT+clump.MultiPRS pT+clump.MultiPRS 0.127 0.127 0.000 1.00e+00 0.130 0.130 0.000 1.00e+00
Depression lassosum.PseudoVal pT+clump.10FCVal 0.079 0.120 -0.042 2.09e-12 0.091 0.120 -0.029 1.52e-02
Depression All.MultiPRS pT+clump.10FCVal 0.144 0.120 0.024 6.04e-04 0.145 0.120 0.026 1.64e-05
Depression DBSLMM.PseudoVal pT+clump.10FCVal 0.139 0.120 0.019 1.66e-09 0.140 0.120 0.020 1.47e-03
Depression LDpred1.Inf pT+clump.10FCVal 0.141 0.120 0.021 9.10e-12 0.137 0.120 0.017 5.54e-03
Depression LDpred2.Inf pT+clump.10FCVal 0.141 0.120 0.021 3.74e-12 0.138 0.120 0.018 2.51e-03
Depression lassosum.MultiPRS pT+clump.10FCVal 0.143 0.120 0.023 1.22e-03 0.144 0.120 0.024 9.42e-05
Depression LDpred1.10FCVal pT+clump.10FCVal 0.142 0.120 0.022 3.04e-13 0.140 0.120 0.020 8.98e-04
Depression pT+clump.MultiPRS pT+clump.10FCVal 0.127 0.120 0.006 3.56e-01 0.130 0.120 0.010 5.91e-04
Depression LDpred2.MultiPRS pT+clump.10FCVal 0.144 0.120 0.024 7.60e-04 0.143 0.120 0.023 2.53e-04
Depression pT+clump.10FCVal pT+clump.10FCVal 0.120 0.120 0.000 1.00e+00 0.120 0.120 0.000 1.00e+00
Depression lassosum.10FCVal pT+clump.10FCVal 0.143 0.120 0.022 6.57e-14 0.143 0.120 0.023 9.26e-05
Depression LDpred2.10FCVal pT+clump.10FCVal 0.144 0.120 0.023 5.02e-14 0.140 0.120 0.020 1.11e-03
Depression SBayesR.PseudoVal pT+clump.10FCVal 0.143 0.120 0.023 5.56e-13 0.143 0.120 0.023 2.86e-04
Depression LDpred1.MultiPRS pT+clump.10FCVal 0.142 0.120 0.022 1.76e-03 0.139 0.120 0.019 1.36e-03
Depression LDpred2.PseudoVal pT+clump.10FCVal 0.142 0.120 0.022 1.48e-13 0.140 0.120 0.020 6.85e-04
Depression SBLUP.Inf pT+clump.10FCVal 0.141 0.120 0.021 4.02e-12 0.137 0.120 0.018 3.05e-03
Depression LDpred1.Inf SBayesR.PseudoVal 0.141 0.143 -0.002 1.78e-01 0.137 0.143 -0.006 3.98e-02
Depression DBSLMM.PseudoVal SBayesR.PseudoVal 0.139 0.143 -0.004 2.39e-02 0.140 0.143 -0.003 4.10e-01
Depression lassosum.PseudoVal SBayesR.PseudoVal 0.079 0.143 -0.064 5.91e-40 0.091 0.143 -0.051 7.65e-08
Depression LDpred2.MultiPRS SBayesR.PseudoVal 0.144 0.143 0.001 8.84e-01 0.143 0.143 0.001 7.11e-01
Depression pT+clump.10FCVal SBayesR.PseudoVal 0.120 0.143 -0.023 5.56e-13 0.120 0.143 -0.023 2.86e-04
Depression lassosum.10FCVal SBayesR.PseudoVal 0.143 0.143 0.000 8.61e-01 0.143 0.143 0.000 8.73e-01
Depression LDpred2.10FCVal SBayesR.PseudoVal 0.144 0.143 0.001 5.79e-01 0.140 0.143 -0.003 2.78e-01
Depression All.MultiPRS SBayesR.PseudoVal 0.144 0.143 0.001 8.34e-01 0.145 0.143 0.003 1.19e-01
Depression LDpred1.MultiPRS SBayesR.PseudoVal 0.142 0.143 -0.001 9.16e-01 0.139 0.143 -0.003 1.55e-01
Depression LDpred2.PseudoVal SBayesR.PseudoVal 0.142 0.143 -0.001 5.70e-01 0.140 0.143 -0.003 2.92e-01
Depression SBLUP.Inf SBayesR.PseudoVal 0.141 0.143 -0.002 1.78e-01 0.137 0.143 -0.005 8.29e-02
Depression pT+clump.MultiPRS SBayesR.PseudoVal 0.127 0.143 -0.016 2.18e-02 0.130 0.143 -0.013 1.43e-02
Depression LDpred2.Inf SBayesR.PseudoVal 0.141 0.143 -0.002 2.00e-01 0.138 0.143 -0.005 1.07e-01
Depression lassosum.MultiPRS SBayesR.PseudoVal 0.143 0.143 0.000 9.90e-01 0.144 0.143 0.002 5.50e-01
Depression LDpred1.10FCVal SBayesR.PseudoVal 0.142 0.143 -0.001 5.10e-01 0.140 0.143 -0.003 2.09e-01
Depression SBayesR.PseudoVal SBayesR.PseudoVal 0.143 0.143 0.000 1.00e+00 0.143 0.143 0.000 1.00e+00
Depression All.MultiPRS SBLUP.Inf 0.144 0.141 0.003 6.23e-01 0.145 0.137 0.008 7.74e-04
Depression LDpred1.Inf SBLUP.Inf 0.141 0.141 0.000 9.73e-01 0.137 0.137 -0.001 5.14e-01
Depression LDpred2.Inf SBLUP.Inf 0.141 0.141 0.000 7.79e-01 0.138 0.137 0.000 6.24e-01
Depression DBSLMM.PseudoVal SBLUP.Inf 0.139 0.141 -0.002 2.51e-01 0.140 0.137 0.002 3.67e-01
Depression lassosum.PseudoVal SBLUP.Inf 0.079 0.141 -0.062 8.45e-30 0.091 0.137 -0.046 1.92e-05
Depression LDpred2.MultiPRS SBLUP.Inf 0.144 0.141 0.003 6.68e-01 0.143 0.137 0.006 9.31e-03
Depression pT+clump.10FCVal SBLUP.Inf 0.120 0.141 -0.021 4.02e-12 0.120 0.137 -0.018 3.05e-03
Depression lassosum.10FCVal SBLUP.Inf 0.143 0.141 0.002 2.43e-01 0.143 0.137 0.006 6.04e-02
Depression LDpred2.10FCVal SBLUP.Inf 0.144 0.141 0.003 5.14e-05 0.140 0.137 0.003 5.09e-02
Depression SBayesR.PseudoVal SBLUP.Inf 0.143 0.141 0.002 1.78e-01 0.143 0.137 0.005 8.29e-02
Depression LDpred1.MultiPRS SBLUP.Inf 0.142 0.141 0.001 8.59e-01 0.139 0.137 0.002 2.66e-01
Depression LDpred2.PseudoVal SBLUP.Inf 0.142 0.141 0.001 1.64e-02 0.140 0.137 0.003 1.92e-02
Depression SBLUP.Inf SBLUP.Inf 0.141 0.141 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
Depression pT+clump.MultiPRS SBLUP.Inf 0.127 0.141 -0.014 4.40e-02 0.130 0.137 -0.007 1.82e-01
Depression lassosum.MultiPRS SBLUP.Inf 0.143 0.141 0.002 7.68e-01 0.144 0.137 0.007 3.29e-02
Depression LDpred1.10FCVal SBLUP.Inf 0.142 0.141 0.001 1.08e-01 0.140 0.137 0.002 1.43e-01
Intelligence lassosum.PseudoVal All.MultiPRS 0.064 0.102 -0.038 8.95e-08 0.055 0.097 -0.043 4.76e-07
Intelligence All.MultiPRS All.MultiPRS 0.102 0.102 0.000 1.00e+00 0.097 0.097 0.000 1.00e+00
Intelligence DBSLMM.PseudoVal All.MultiPRS 0.090 0.102 -0.012 8.98e-02 0.082 0.097 -0.015 1.55e-03
Intelligence LDpred1.Inf All.MultiPRS 0.099 0.102 -0.004 6.04e-01 0.094 0.097 -0.004 2.74e-01
Intelligence LDpred2.Inf All.MultiPRS 0.099 0.102 -0.003 6.59e-01 0.094 0.097 -0.003 3.81e-01
Intelligence lassosum.MultiPRS All.MultiPRS 0.102 0.102 0.000 6.94e-01 0.099 0.097 0.002 3.09e-01
Intelligence LDpred1.10FCVal All.MultiPRS 0.100 0.102 -0.002 8.02e-01 0.094 0.097 -0.003 2.38e-01
Intelligence pT+clump.MultiPRS All.MultiPRS 0.087 0.102 -0.016 2.63e-02 0.081 0.097 -0.016 4.05e-03
Intelligence LDpred2.MultiPRS All.MultiPRS 0.103 0.102 0.001 9.29e-01 0.098 0.097 0.001 7.16e-01
Intelligence pT+clump.10FCVal All.MultiPRS 0.084 0.102 -0.018 8.92e-03 0.074 0.097 -0.023 2.53e-04
Intelligence lassosum.10FCVal All.MultiPRS 0.098 0.102 -0.004 5.74e-01 0.096 0.097 -0.002 6.41e-01
Intelligence LDpred2.10FCVal All.MultiPRS 0.102 0.102 -0.001 9.42e-01 0.095 0.097 -0.002 4.83e-01
Intelligence SBayesR.PseudoVal All.MultiPRS 0.100 0.102 -0.002 7.39e-01 0.090 0.097 -0.007 2.56e-02
Intelligence LDpred1.MultiPRS All.MultiPRS 0.101 0.102 -0.002 8.23e-01 0.094 0.097 -0.003 2.60e-01
Intelligence LDpred2.PseudoVal All.MultiPRS 0.100 0.102 -0.002 7.81e-01 0.095 0.097 -0.002 4.89e-01
Intelligence SBLUP.Inf All.MultiPRS 0.099 0.102 -0.003 6.65e-01 0.094 0.097 -0.004 2.57e-01
Intelligence LDpred2.MultiPRS DBSLMM.PseudoVal 0.103 0.090 0.013 7.38e-02 0.098 0.082 0.016 1.97e-03
Intelligence pT+clump.10FCVal DBSLMM.PseudoVal 0.084 0.090 -0.007 9.44e-02 0.074 0.082 -0.008 3.05e-01
Intelligence lassosum.PseudoVal DBSLMM.PseudoVal 0.064 0.090 -0.026 1.66e-08 0.055 0.082 -0.027 3.10e-03
Intelligence All.MultiPRS DBSLMM.PseudoVal 0.102 0.090 0.012 8.98e-02 0.097 0.082 0.015 1.55e-03
Intelligence LDpred1.MultiPRS DBSLMM.PseudoVal 0.101 0.090 0.010 1.21e-01 0.094 0.082 0.012 1.43e-02
Intelligence LDpred2.PseudoVal DBSLMM.PseudoVal 0.100 0.090 0.010 4.57e-05 0.095 0.082 0.013 6.29e-03
Intelligence DBSLMM.PseudoVal DBSLMM.PseudoVal 0.090 0.090 0.000 1.00e+00 0.082 0.082 0.000 1.00e+00
Intelligence LDpred1.Inf DBSLMM.PseudoVal 0.099 0.090 0.008 1.63e-03 0.094 0.082 0.012 2.61e-02
Intelligence LDpred2.Inf DBSLMM.PseudoVal 0.099 0.090 0.009 4.77e-04 0.094 0.082 0.012 1.29e-02
Intelligence lassosum.MultiPRS DBSLMM.PseudoVal 0.102 0.090 0.012 1.00e-01 0.099 0.082 0.017 5.67e-04
Intelligence LDpred1.10FCVal DBSLMM.PseudoVal 0.100 0.090 0.010 5.33e-05 0.094 0.082 0.012 1.79e-02
Intelligence pT+clump.MultiPRS DBSLMM.PseudoVal 0.087 0.090 -0.004 6.01e-01 0.081 0.082 -0.001 9.37e-01
Intelligence SBayesR.PseudoVal DBSLMM.PseudoVal 0.100 0.090 0.010 3.90e-04 0.090 0.082 0.008 1.32e-01
Intelligence lassosum.10FCVal DBSLMM.PseudoVal 0.098 0.090 0.008 5.50e-03 0.096 0.082 0.014 1.72e-02
Intelligence LDpred2.10FCVal DBSLMM.PseudoVal 0.102 0.090 0.011 7.33e-07 0.095 0.082 0.014 3.44e-03
Intelligence SBLUP.Inf DBSLMM.PseudoVal 0.099 0.090 0.009 4.11e-04 0.094 0.082 0.012 1.98e-02
Intelligence All.MultiPRS lassosum.MultiPRS 0.102 0.102 0.000 6.94e-01 0.097 0.099 -0.002 3.09e-01
Intelligence LDpred1.MultiPRS lassosum.MultiPRS 0.101 0.102 -0.001 8.65e-01 0.094 0.099 -0.005 1.18e-01
Intelligence LDpred1.Inf lassosum.MultiPRS 0.099 0.102 -0.003 6.41e-01 0.094 0.099 -0.005 1.31e-01
Intelligence LDpred2.Inf lassosum.MultiPRS 0.099 0.102 -0.003 6.97e-01 0.094 0.099 -0.005 1.63e-01
Intelligence lassosum.MultiPRS lassosum.MultiPRS 0.102 0.102 0.000 1.00e+00 0.099 0.099 0.000 1.00e+00
Intelligence DBSLMM.PseudoVal lassosum.MultiPRS 0.090 0.102 -0.012 1.00e-01 0.082 0.099 -0.017 5.67e-04
Intelligence lassosum.PseudoVal lassosum.MultiPRS 0.064 0.102 -0.037 1.18e-07 0.055 0.099 -0.044 1.21e-07
Intelligence LDpred2.MultiPRS lassosum.MultiPRS 0.103 0.102 0.001 8.86e-01 0.098 0.099 -0.001 7.87e-01
Intelligence pT+clump.10FCVal lassosum.MultiPRS 0.084 0.102 -0.018 1.04e-02 0.074 0.099 -0.025 1.36e-04
Intelligence lassosum.10FCVal lassosum.MultiPRS 0.098 0.102 -0.004 6.11e-01 0.096 0.099 -0.003 2.32e-01
Intelligence LDpred2.10FCVal lassosum.MultiPRS 0.102 0.102 0.000 9.84e-01 0.095 0.099 -0.004 1.67e-01
Intelligence SBayesR.PseudoVal lassosum.MultiPRS 0.100 0.102 -0.002 7.79e-01 0.090 0.099 -0.009 1.54e-02
Intelligence LDpred2.PseudoVal lassosum.MultiPRS 0.100 0.102 -0.002 8.22e-01 0.095 0.099 -0.004 2.03e-01
Intelligence SBLUP.Inf lassosum.MultiPRS 0.099 0.102 -0.003 7.03e-01 0.094 0.099 -0.005 1.00e-01
Intelligence pT+clump.MultiPRS lassosum.MultiPRS 0.087 0.102 -0.015 3.00e-02 0.081 0.099 -0.018 2.04e-03
Intelligence LDpred1.10FCVal lassosum.MultiPRS 0.100 0.102 -0.001 8.43e-01 0.094 0.099 -0.005 1.02e-01
Intelligence All.MultiPRS lassosum.PseudoVal 0.102 0.064 0.038 8.95e-08 0.097 0.055 0.043 4.76e-07
Intelligence LDpred1.MultiPRS lassosum.PseudoVal 0.101 0.064 0.036 9.47e-08 0.094 0.055 0.040 2.54e-06
Intelligence LDpred2.PseudoVal lassosum.PseudoVal 0.100 0.064 0.036 3.13e-14 0.095 0.055 0.041 1.64e-05
Intelligence DBSLMM.PseudoVal lassosum.PseudoVal 0.090 0.064 0.026 1.66e-08 0.082 0.055 0.027 3.10e-03
Intelligence LDpred1.Inf lassosum.PseudoVal 0.099 0.064 0.034 6.88e-12 0.094 0.055 0.039 8.86e-05
Intelligence LDpred2.Inf lassosum.PseudoVal 0.099 0.064 0.035 2.34e-12 0.094 0.055 0.040 5.65e-05
Intelligence lassosum.MultiPRS lassosum.PseudoVal 0.102 0.064 0.037 1.18e-07 0.099 0.055 0.044 1.21e-07
Intelligence LDpred1.10FCVal lassosum.PseudoVal 0.100 0.064 0.036 9.81e-17 0.094 0.055 0.039 5.66e-06
Intelligence lassosum.PseudoVal lassosum.PseudoVal 0.064 0.064 0.000 1.00e+00 0.055 0.055 0.000 1.00e+00
Intelligence LDpred2.MultiPRS lassosum.PseudoVal 0.103 0.064 0.038 4.26e-08 0.098 0.055 0.043 6.57e-07
Intelligence pT+clump.10FCVal lassosum.PseudoVal 0.084 0.064 0.019 2.57e-04 0.074 0.055 0.019 6.68e-02
Intelligence lassosum.10FCVal lassosum.PseudoVal 0.098 0.064 0.034 5.72e-13 0.096 0.055 0.041 1.31e-05
Intelligence LDpred2.10FCVal lassosum.PseudoVal 0.102 0.064 0.037 1.25e-19 0.095 0.055 0.041 6.72e-07
Intelligence SBayesR.PseudoVal lassosum.PseudoVal 0.100 0.064 0.036 1.09e-18 0.090 0.055 0.036 9.83e-06
Intelligence SBLUP.Inf lassosum.PseudoVal 0.099 0.064 0.035 2.11e-12 0.094 0.055 0.039 7.96e-05
Intelligence pT+clump.MultiPRS lassosum.PseudoVal 0.087 0.064 0.022 1.60e-03 0.081 0.055 0.027 2.40e-03
Intelligence All.MultiPRS lassosum.10FCVal 0.102 0.098 0.004 5.74e-01 0.097 0.096 0.002 6.41e-01
Intelligence LDpred1.MultiPRS lassosum.10FCVal 0.101 0.098 0.002 7.18e-01 0.094 0.096 -0.001 7.06e-01
Intelligence LDpred1.Inf lassosum.10FCVal 0.099 0.098 0.000 8.64e-01 0.094 0.096 -0.002 5.74e-01
Intelligence LDpred2.Inf lassosum.10FCVal 0.099 0.098 0.001 6.01e-01 0.094 0.096 -0.001 7.27e-01
Intelligence lassosum.MultiPRS lassosum.10FCVal 0.102 0.098 0.004 6.11e-01 0.099 0.096 0.003 2.32e-01
Intelligence DBSLMM.PseudoVal lassosum.10FCVal 0.090 0.098 -0.008 5.50e-03 0.082 0.096 -0.014 1.72e-02
Intelligence lassosum.PseudoVal lassosum.10FCVal 0.064 0.098 -0.034 5.72e-13 0.055 0.096 -0.041 1.31e-05
Intelligence LDpred2.MultiPRS lassosum.10FCVal 0.103 0.098 0.005 5.13e-01 0.098 0.096 0.003 5.75e-01
Intelligence pT+clump.10FCVal lassosum.10FCVal 0.084 0.098 -0.014 3.17e-07 0.074 0.096 -0.022 1.27e-04
Intelligence lassosum.10FCVal lassosum.10FCVal 0.098 0.098 0.000 1.00e+00 0.096 0.096 0.000 1.00e+00
Intelligence LDpred2.10FCVal lassosum.10FCVal 0.102 0.098 0.003 5.35e-02 0.095 0.096 0.000 9.86e-01
Intelligence SBayesR.PseudoVal lassosum.10FCVal 0.100 0.098 0.002 4.10e-01 0.090 0.096 -0.005 1.67e-01
Intelligence LDpred2.PseudoVal lassosum.10FCVal 0.100 0.098 0.002 1.69e-01 0.095 0.096 0.000 9.19e-01
Intelligence SBLUP.Inf lassosum.10FCVal 0.099 0.098 0.001 5.75e-01 0.094 0.096 -0.002 5.42e-01
Intelligence pT+clump.MultiPRS lassosum.10FCVal 0.087 0.098 -0.012 9.69e-02 0.081 0.096 -0.014 9.48e-03
Intelligence LDpred1.10FCVal lassosum.10FCVal 0.100 0.098 0.002 1.95e-01 0.094 0.096 -0.002 6.22e-01
Intelligence DBSLMM.PseudoVal LDpred1.MultiPRS 0.090 0.101 -0.010 1.21e-01 0.082 0.094 -0.012 1.43e-02
Intelligence LDpred2.MultiPRS LDpred1.MultiPRS 0.103 0.101 0.002 7.55e-01 0.098 0.094 0.004 2.57e-01
Intelligence pT+clump.10FCVal LDpred1.MultiPRS 0.084 0.101 -0.017 1.21e-02 0.074 0.094 -0.020 1.88e-03
Intelligence lassosum.10FCVal LDpred1.MultiPRS 0.098 0.101 -0.002 7.18e-01 0.096 0.094 0.001 7.06e-01
Intelligence lassosum.PseudoVal LDpred1.MultiPRS 0.064 0.101 -0.036 9.47e-08 0.055 0.094 -0.040 2.54e-06
Intelligence All.MultiPRS LDpred1.MultiPRS 0.102 0.101 0.002 8.23e-01 0.097 0.094 0.003 2.60e-01
Intelligence LDpred1.MultiPRS LDpred1.MultiPRS 0.101 0.101 0.000 1.00e+00 0.094 0.094 0.000 1.00e+00
Intelligence LDpred2.PseudoVal LDpred1.MultiPRS 0.100 0.101 0.000 9.51e-01 0.095 0.094 0.001 6.24e-01
Intelligence SBLUP.Inf LDpred1.MultiPRS 0.099 0.101 -0.002 8.21e-01 0.094 0.094 -0.001 8.14e-01
Intelligence LDpred1.Inf LDpred1.MultiPRS 0.099 0.101 -0.002 7.51e-01 0.094 0.094 -0.001 7.67e-01
Intelligence LDpred2.Inf LDpred1.MultiPRS 0.099 0.101 -0.002 8.15e-01 0.094 0.094 0.000 9.28e-01
Intelligence lassosum.MultiPRS LDpred1.MultiPRS 0.102 0.101 0.001 8.65e-01 0.099 0.094 0.005 1.18e-01
Intelligence LDpred1.10FCVal LDpred1.MultiPRS 0.100 0.101 0.000 9.74e-01 0.094 0.094 0.000 7.75e-01
Intelligence pT+clump.MultiPRS LDpred1.MultiPRS 0.087 0.101 -0.014 4.55e-02 0.081 0.094 -0.013 2.59e-02
Intelligence SBayesR.PseudoVal LDpred1.MultiPRS 0.100 0.101 -0.001 9.05e-01 0.090 0.094 -0.004 1.40e-01
Intelligence LDpred2.10FCVal LDpred1.MultiPRS 0.102 0.101 0.001 8.76e-01 0.095 0.094 0.001 5.07e-01
Intelligence All.MultiPRS LDpred1.Inf 0.102 0.099 0.004 6.04e-01 0.097 0.094 0.004 2.74e-01
Intelligence LDpred1.Inf LDpred1.Inf 0.099 0.099 0.000 1.00e+00 0.094 0.094 0.000 1.00e+00
Intelligence LDpred2.Inf LDpred1.Inf 0.099 0.099 0.001 5.23e-01 0.094 0.094 0.001 6.05e-01
Intelligence DBSLMM.PseudoVal LDpred1.Inf 0.090 0.099 -0.008 1.63e-03 0.082 0.094 -0.012 2.61e-02
Intelligence lassosum.PseudoVal LDpred1.Inf 0.064 0.099 -0.034 6.88e-12 0.055 0.094 -0.039 8.86e-05
Intelligence LDpred2.MultiPRS LDpred1.Inf 0.103 0.099 0.004 5.41e-01 0.098 0.094 0.005 2.53e-01
Intelligence pT+clump.10FCVal LDpred1.Inf 0.084 0.099 -0.015 3.24e-06 0.074 0.094 -0.020 1.85e-03
Intelligence lassosum.10FCVal LDpred1.Inf 0.098 0.099 0.000 8.64e-01 0.096 0.094 0.002 5.74e-01
Intelligence LDpred2.10FCVal LDpred1.Inf 0.102 0.099 0.003 3.31e-02 0.095 0.094 0.002 5.09e-01
Intelligence SBayesR.PseudoVal LDpred1.Inf 0.100 0.099 0.001 4.85e-01 0.090 0.094 -0.003 3.58e-01
Intelligence LDpred1.MultiPRS LDpred1.Inf 0.101 0.099 0.002 7.51e-01 0.094 0.094 0.001 7.67e-01
Intelligence LDpred2.PseudoVal LDpred1.Inf 0.100 0.099 0.002 6.60e-02 0.095 0.094 0.002 3.53e-01
Intelligence SBLUP.Inf LDpred1.Inf 0.099 0.099 0.001 4.75e-01 0.094 0.094 0.000 9.81e-01
Intelligence pT+clump.MultiPRS LDpred1.Inf 0.087 0.099 -0.012 8.87e-02 0.081 0.094 -0.012 4.90e-02
Intelligence lassosum.MultiPRS LDpred1.Inf 0.102 0.099 0.003 6.41e-01 0.099 0.094 0.005 1.31e-01
Intelligence LDpred1.10FCVal LDpred1.Inf 0.100 0.099 0.002 7.36e-02 0.094 0.094 0.000 8.85e-01
Intelligence LDpred1.Inf LDpred1.10FCVal 0.099 0.100 -0.002 7.36e-02 0.094 0.094 0.000 8.85e-01
Intelligence DBSLMM.PseudoVal LDpred1.10FCVal 0.090 0.100 -0.010 5.33e-05 0.082 0.094 -0.012 1.79e-02
Intelligence lassosum.PseudoVal LDpred1.10FCVal 0.064 0.100 -0.036 9.81e-17 0.055 0.094 -0.039 5.66e-06
Intelligence LDpred2.MultiPRS LDpred1.10FCVal 0.103 0.100 0.002 7.33e-01 0.098 0.094 0.004 2.41e-01
Intelligence pT+clump.10FCVal LDpred1.10FCVal 0.084 0.100 -0.017 2.79e-07 0.074 0.094 -0.020 1.99e-03
Intelligence lassosum.10FCVal LDpred1.10FCVal 0.098 0.100 -0.002 1.95e-01 0.096 0.094 0.002 6.22e-01
Intelligence LDpred2.10FCVal LDpred1.10FCVal 0.102 0.100 0.001 2.06e-01 0.095 0.094 0.002 4.10e-01
Intelligence All.MultiPRS LDpred1.10FCVal 0.102 0.100 0.002 8.02e-01 0.097 0.094 0.003 2.38e-01
Intelligence LDpred1.MultiPRS LDpred1.10FCVal 0.101 0.100 0.000 9.74e-01 0.094 0.094 0.000 7.75e-01
Intelligence LDpred2.PseudoVal LDpred1.10FCVal 0.100 0.100 0.000 8.57e-01 0.095 0.094 0.001 5.15e-01
Intelligence SBLUP.Inf LDpred1.10FCVal 0.099 0.100 -0.001 3.15e-01 0.094 0.094 0.000 9.18e-01
Intelligence pT+clump.MultiPRS LDpred1.10FCVal 0.087 0.100 -0.014 4.88e-02 0.081 0.094 -0.012 3.06e-02
Intelligence LDpred2.Inf LDpred1.10FCVal 0.099 0.100 -0.001 2.97e-01 0.094 0.094 0.001 8.27e-01
Intelligence lassosum.MultiPRS LDpred1.10FCVal 0.102 0.100 0.001 8.43e-01 0.099 0.094 0.005 1.02e-01
Intelligence LDpred1.10FCVal LDpred1.10FCVal 0.100 0.100 0.000 1.00e+00 0.094 0.094 0.000 1.00e+00
Intelligence SBayesR.PseudoVal LDpred1.10FCVal 0.100 0.100 -0.001 6.76e-01 0.090 0.094 -0.004 1.79e-01
Intelligence LDpred2.MultiPRS LDpred2.MultiPRS 0.103 0.103 0.000 1.00e+00 0.098 0.098 0.000 1.00e+00
Intelligence lassosum.PseudoVal LDpred2.MultiPRS 0.064 0.103 -0.038 4.26e-08 0.055 0.098 -0.043 6.57e-07
Intelligence All.MultiPRS LDpred2.MultiPRS 0.102 0.103 -0.001 9.29e-01 0.097 0.098 -0.001 7.16e-01
Intelligence LDpred1.MultiPRS LDpred2.MultiPRS 0.101 0.103 -0.002 7.55e-01 0.094 0.098 -0.004 2.57e-01
Intelligence DBSLMM.PseudoVal LDpred2.MultiPRS 0.090 0.103 -0.013 7.38e-02 0.082 0.098 -0.016 1.97e-03
Intelligence LDpred1.Inf LDpred2.MultiPRS 0.099 0.103 -0.004 5.41e-01 0.094 0.098 -0.005 2.53e-01
Intelligence LDpred2.Inf LDpred2.MultiPRS 0.099 0.103 -0.004 5.94e-01 0.094 0.098 -0.004 3.09e-01
Intelligence lassosum.MultiPRS LDpred2.MultiPRS 0.102 0.103 -0.001 8.86e-01 0.099 0.098 0.001 7.87e-01
Intelligence LDpred1.10FCVal LDpred2.MultiPRS 0.100 0.103 -0.002 7.33e-01 0.094 0.098 -0.004 2.41e-01
Intelligence pT+clump.MultiPRS LDpred2.MultiPRS 0.087 0.103 -0.016 2.18e-02 0.081 0.098 -0.017 8.35e-03
Intelligence SBayesR.PseudoVal LDpred2.MultiPRS 0.100 0.103 -0.003 6.72e-01 0.090 0.098 -0.008 4.77e-02
Intelligence pT+clump.10FCVal LDpred2.MultiPRS 0.084 0.103 -0.019 6.51e-03 0.074 0.098 -0.024 7.49e-04
Intelligence lassosum.10FCVal LDpred2.MultiPRS 0.098 0.103 -0.005 5.13e-01 0.096 0.098 -0.003 5.75e-01
Intelligence LDpred2.10FCVal LDpred2.MultiPRS 0.102 0.103 -0.001 8.70e-01 0.095 0.098 -0.003 3.91e-01
Intelligence LDpred2.PseudoVal LDpred2.MultiPRS 0.100 0.103 -0.003 7.12e-01 0.095 0.098 -0.003 3.96e-01
Intelligence SBLUP.Inf LDpred2.MultiPRS 0.099 0.103 -0.004 6.00e-01 0.094 0.098 -0.004 2.20e-01
Intelligence LDpred2.MultiPRS LDpred2.10FCVal 0.103 0.102 0.001 8.70e-01 0.098 0.095 0.003 3.91e-01
Intelligence pT+clump.10FCVal LDpred2.10FCVal 0.084 0.102 -0.018 1.35e-07 0.074 0.095 -0.021 1.47e-03
Intelligence lassosum.PseudoVal LDpred2.10FCVal 0.064 0.102 -0.037 1.25e-19 0.055 0.095 -0.041 6.72e-07
Intelligence All.MultiPRS LDpred2.10FCVal 0.102 0.102 0.001 9.42e-01 0.097 0.095 0.002 4.83e-01
Intelligence LDpred1.MultiPRS LDpred2.10FCVal 0.101 0.102 -0.001 8.76e-01 0.094 0.095 -0.001 5.07e-01
Intelligence LDpred2.PseudoVal LDpred2.10FCVal 0.100 0.102 -0.001 1.26e-01 0.095 0.095 0.000 9.03e-01
Intelligence DBSLMM.PseudoVal LDpred2.10FCVal 0.090 0.102 -0.011 7.33e-07 0.082 0.095 -0.014 3.44e-03
Intelligence LDpred1.Inf LDpred2.10FCVal 0.099 0.102 -0.003 3.31e-02 0.094 0.095 -0.002 5.09e-01
Intelligence LDpred2.Inf LDpred2.10FCVal 0.099 0.102 -0.003 3.35e-02 0.094 0.095 -0.001 6.65e-01
Intelligence lassosum.MultiPRS LDpred2.10FCVal 0.102 0.102 0.000 9.84e-01 0.099 0.095 0.004 1.67e-01
Intelligence LDpred1.10FCVal LDpred2.10FCVal 0.100 0.102 -0.001 2.06e-01 0.094 0.095 -0.002 4.10e-01
Intelligence pT+clump.MultiPRS LDpred2.10FCVal 0.087 0.102 -0.015 3.15e-02 0.081 0.095 -0.014 1.67e-02
Intelligence SBayesR.PseudoVal LDpred2.10FCVal 0.100 0.102 -0.002 1.81e-01 0.090 0.095 -0.005 5.17e-02
Intelligence lassosum.10FCVal LDpred2.10FCVal 0.098 0.102 -0.003 5.35e-02 0.096 0.095 0.000 9.86e-01
Intelligence LDpred2.10FCVal LDpred2.10FCVal 0.102 0.102 0.000 1.00e+00 0.095 0.095 0.000 1.00e+00
Intelligence SBLUP.Inf LDpred2.10FCVal 0.099 0.102 -0.003 4.24e-02 0.094 0.095 -0.002 4.51e-01
Intelligence LDpred2.MultiPRS LDpred2.PseudoVal 0.103 0.100 0.003 7.12e-01 0.098 0.095 0.003 3.96e-01
Intelligence lassosum.PseudoVal LDpred2.PseudoVal 0.064 0.100 -0.036 3.13e-14 0.055 0.095 -0.041 1.64e-05
Intelligence All.MultiPRS LDpred2.PseudoVal 0.102 0.100 0.002 7.81e-01 0.097 0.095 0.002 4.89e-01
Intelligence LDpred1.MultiPRS LDpred2.PseudoVal 0.101 0.100 0.000 9.51e-01 0.094 0.095 -0.001 6.24e-01
Intelligence DBSLMM.PseudoVal LDpred2.PseudoVal 0.090 0.100 -0.010 4.57e-05 0.082 0.095 -0.013 6.29e-03
Intelligence LDpred1.Inf LDpred2.PseudoVal 0.099 0.100 -0.002 6.60e-02 0.094 0.095 -0.002 3.53e-01
Intelligence LDpred2.Inf LDpred2.PseudoVal 0.099 0.100 -0.001 1.81e-03 0.094 0.095 -0.001 2.60e-01
Intelligence lassosum.MultiPRS LDpred2.PseudoVal 0.102 0.100 0.002 8.22e-01 0.099 0.095 0.004 2.03e-01
Intelligence LDpred1.10FCVal LDpred2.PseudoVal 0.100 0.100 0.000 8.57e-01 0.094 0.095 -0.001 5.15e-01
Intelligence pT+clump.MultiPRS LDpred2.PseudoVal 0.087 0.100 -0.014 5.18e-02 0.081 0.095 -0.014 1.83e-02
Intelligence SBayesR.PseudoVal LDpred2.PseudoVal 0.100 0.100 0.000 8.12e-01 0.090 0.095 -0.005 1.19e-01
Intelligence pT+clump.10FCVal LDpred2.PseudoVal 0.084 0.100 -0.016 1.11e-07 0.074 0.095 -0.021 5.47e-04
Intelligence lassosum.10FCVal LDpred2.PseudoVal 0.098 0.100 -0.002 1.69e-01 0.096 0.095 0.000 9.19e-01
Intelligence LDpred2.10FCVal LDpred2.PseudoVal 0.102 0.100 0.001 1.26e-01 0.095 0.095 0.000 9.03e-01
Intelligence LDpred2.PseudoVal LDpred2.PseudoVal 0.100 0.100 0.000 1.00e+00 0.095 0.095 0.000 1.00e+00
Intelligence SBLUP.Inf LDpred2.PseudoVal 0.099 0.100 -0.001 2.27e-02 0.094 0.095 -0.002 8.13e-02
Intelligence DBSLMM.PseudoVal LDpred2.Inf 0.090 0.099 -0.009 4.77e-04 0.082 0.094 -0.012 1.29e-02
Intelligence LDpred2.MultiPRS LDpred2.Inf 0.103 0.099 0.004 5.94e-01 0.098 0.094 0.004 3.09e-01
Intelligence pT+clump.10FCVal LDpred2.Inf 0.084 0.099 -0.015 1.14e-06 0.074 0.094 -0.020 1.05e-03
Intelligence lassosum.10FCVal LDpred2.Inf 0.098 0.099 -0.001 6.01e-01 0.096 0.094 0.001 7.27e-01
Intelligence lassosum.PseudoVal LDpred2.Inf 0.064 0.099 -0.035 2.34e-12 0.055 0.094 -0.040 5.65e-05
Intelligence All.MultiPRS LDpred2.Inf 0.102 0.099 0.003 6.59e-01 0.097 0.094 0.003 3.81e-01
Intelligence LDpred1.MultiPRS LDpred2.Inf 0.101 0.099 0.002 8.15e-01 0.094 0.094 0.000 9.28e-01
Intelligence LDpred2.PseudoVal LDpred2.Inf 0.100 0.099 0.001 1.81e-03 0.095 0.094 0.001 2.60e-01
Intelligence SBLUP.Inf LDpred2.Inf 0.099 0.099 0.000 8.40e-01 0.094 0.094 -0.001 1.42e-01
Intelligence LDpred1.Inf LDpred2.Inf 0.099 0.099 -0.001 5.23e-01 0.094 0.094 -0.001 6.05e-01
Intelligence LDpred2.Inf LDpred2.Inf 0.099 0.099 0.000 1.00e+00 0.094 0.094 0.000 1.00e+00
Intelligence lassosum.MultiPRS LDpred2.Inf 0.102 0.099 0.003 6.97e-01 0.099 0.094 0.005 1.63e-01
Intelligence LDpred1.10FCVal LDpred2.Inf 0.100 0.099 0.001 2.97e-01 0.094 0.094 -0.001 8.27e-01
Intelligence pT+clump.MultiPRS LDpred2.Inf 0.087 0.099 -0.013 7.50e-02 0.081 0.094 -0.013 3.39e-02
Intelligence SBayesR.PseudoVal LDpred2.Inf 0.100 0.099 0.001 6.83e-01 0.090 0.094 -0.004 2.52e-01
Intelligence LDpred2.10FCVal LDpred2.Inf 0.102 0.099 0.003 3.35e-02 0.095 0.094 0.001 6.65e-01
Intelligence All.MultiPRS pT+clump.MultiPRS 0.102 0.087 0.016 2.63e-02 0.097 0.081 0.016 4.05e-03
Intelligence LDpred1.MultiPRS pT+clump.MultiPRS 0.101 0.087 0.014 4.55e-02 0.094 0.081 0.013 2.59e-02
Intelligence LDpred2.PseudoVal pT+clump.MultiPRS 0.100 0.087 0.014 5.18e-02 0.095 0.081 0.014 1.83e-02
Intelligence DBSLMM.PseudoVal pT+clump.MultiPRS 0.090 0.087 0.004 6.01e-01 0.082 0.081 0.001 9.37e-01
Intelligence LDpred1.Inf pT+clump.MultiPRS 0.099 0.087 0.012 8.87e-02 0.094 0.081 0.012 4.90e-02
Intelligence LDpred2.Inf pT+clump.MultiPRS 0.099 0.087 0.013 7.50e-02 0.094 0.081 0.013 3.39e-02
Intelligence lassosum.MultiPRS pT+clump.MultiPRS 0.102 0.087 0.015 3.00e-02 0.099 0.081 0.018 2.04e-03
Intelligence LDpred1.10FCVal pT+clump.MultiPRS 0.100 0.087 0.014 4.88e-02 0.094 0.081 0.012 3.06e-02
Intelligence lassosum.PseudoVal pT+clump.MultiPRS 0.064 0.087 -0.022 1.60e-03 0.055 0.081 -0.027 2.40e-03
Intelligence LDpred2.MultiPRS pT+clump.MultiPRS 0.103 0.087 0.016 2.18e-02 0.098 0.081 0.017 8.35e-03
Intelligence pT+clump.10FCVal pT+clump.MultiPRS 0.084 0.087 -0.003 6.87e-01 0.074 0.081 -0.007 1.15e-02
Intelligence lassosum.10FCVal pT+clump.MultiPRS 0.098 0.087 0.012 9.69e-02 0.096 0.081 0.014 9.48e-03
Intelligence LDpred2.10FCVal pT+clump.MultiPRS 0.102 0.087 0.015 3.15e-02 0.095 0.081 0.014 1.67e-02
Intelligence SBayesR.PseudoVal pT+clump.MultiPRS 0.100 0.087 0.013 5.90e-02 0.090 0.081 0.009 1.39e-01
Intelligence SBLUP.Inf pT+clump.MultiPRS 0.099 0.087 0.013 7.37e-02 0.094 0.081 0.012 4.41e-02
Intelligence pT+clump.MultiPRS pT+clump.MultiPRS 0.087 0.087 0.000 1.00e+00 0.081 0.081 0.000 1.00e+00
Intelligence lassosum.PseudoVal pT+clump.10FCVal 0.064 0.084 -0.019 2.57e-04 0.055 0.074 -0.019 6.68e-02
Intelligence All.MultiPRS pT+clump.10FCVal 0.102 0.084 0.018 8.92e-03 0.097 0.074 0.023 2.53e-04
Intelligence DBSLMM.PseudoVal pT+clump.10FCVal 0.090 0.084 0.007 9.44e-02 0.082 0.074 0.008 3.05e-01
Intelligence LDpred1.Inf pT+clump.10FCVal 0.099 0.084 0.015 3.24e-06 0.094 0.074 0.020 1.85e-03
Intelligence LDpred2.Inf pT+clump.10FCVal 0.099 0.084 0.015 1.14e-06 0.094 0.074 0.020 1.05e-03
Intelligence lassosum.MultiPRS pT+clump.10FCVal 0.102 0.084 0.018 1.04e-02 0.099 0.074 0.025 1.36e-04
Intelligence LDpred1.10FCVal pT+clump.10FCVal 0.100 0.084 0.017 2.79e-07 0.094 0.074 0.020 1.99e-03
Intelligence pT+clump.MultiPRS pT+clump.10FCVal 0.087 0.084 0.003 6.87e-01 0.081 0.074 0.007 1.15e-02
Intelligence LDpred2.MultiPRS pT+clump.10FCVal 0.103 0.084 0.019 6.51e-03 0.098 0.074 0.024 7.49e-04
Intelligence pT+clump.10FCVal pT+clump.10FCVal 0.084 0.084 0.000 1.00e+00 0.074 0.074 0.000 1.00e+00
Intelligence lassosum.10FCVal pT+clump.10FCVal 0.098 0.084 0.014 3.17e-07 0.096 0.074 0.022 1.27e-04
Intelligence LDpred2.10FCVal pT+clump.10FCVal 0.102 0.084 0.018 1.35e-07 0.095 0.074 0.021 1.47e-03
Intelligence SBayesR.PseudoVal pT+clump.10FCVal 0.100 0.084 0.016 2.95e-06 0.090 0.074 0.016 1.84e-02
Intelligence LDpred1.MultiPRS pT+clump.10FCVal 0.101 0.084 0.017 1.21e-02 0.094 0.074 0.020 1.88e-03
Intelligence LDpred2.PseudoVal pT+clump.10FCVal 0.100 0.084 0.016 1.11e-07 0.095 0.074 0.021 5.47e-04
Intelligence SBLUP.Inf pT+clump.10FCVal 0.099 0.084 0.015 7.46e-07 0.094 0.074 0.020 1.45e-03
Intelligence LDpred1.Inf SBayesR.PseudoVal 0.099 0.100 -0.001 4.85e-01 0.094 0.090 0.003 3.58e-01
Intelligence DBSLMM.PseudoVal SBayesR.PseudoVal 0.090 0.100 -0.010 3.90e-04 0.082 0.090 -0.008 1.32e-01
Intelligence lassosum.PseudoVal SBayesR.PseudoVal 0.064 0.100 -0.036 1.09e-18 0.055 0.090 -0.036 9.83e-06
Intelligence LDpred2.MultiPRS SBayesR.PseudoVal 0.103 0.100 0.003 6.72e-01 0.098 0.090 0.008 4.77e-02
Intelligence pT+clump.10FCVal SBayesR.PseudoVal 0.084 0.100 -0.016 2.95e-06 0.074 0.090 -0.016 1.84e-02
Intelligence lassosum.10FCVal SBayesR.PseudoVal 0.098 0.100 -0.002 4.10e-01 0.096 0.090 0.005 1.67e-01
Intelligence LDpred2.10FCVal SBayesR.PseudoVal 0.102 0.100 0.002 1.81e-01 0.095 0.090 0.005 5.17e-02
Intelligence All.MultiPRS SBayesR.PseudoVal 0.102 0.100 0.002 7.39e-01 0.097 0.090 0.007 2.56e-02
Intelligence LDpred1.MultiPRS SBayesR.PseudoVal 0.101 0.100 0.001 9.05e-01 0.094 0.090 0.004 1.40e-01
Intelligence LDpred2.PseudoVal SBayesR.PseudoVal 0.100 0.100 0.000 8.12e-01 0.095 0.090 0.005 1.19e-01
Intelligence SBLUP.Inf SBayesR.PseudoVal 0.099 0.100 -0.001 7.09e-01 0.094 0.090 0.003 3.59e-01
Intelligence pT+clump.MultiPRS SBayesR.PseudoVal 0.087 0.100 -0.013 5.90e-02 0.081 0.090 -0.009 1.39e-01
Intelligence LDpred2.Inf SBayesR.PseudoVal 0.099 0.100 -0.001 6.83e-01 0.094 0.090 0.004 2.52e-01
Intelligence lassosum.MultiPRS SBayesR.PseudoVal 0.102 0.100 0.002 7.79e-01 0.099 0.090 0.009 1.54e-02
Intelligence LDpred1.10FCVal SBayesR.PseudoVal 0.100 0.100 0.001 6.76e-01 0.094 0.090 0.004 1.79e-01
Intelligence SBayesR.PseudoVal SBayesR.PseudoVal 0.100 0.100 0.000 1.00e+00 0.090 0.090 0.000 1.00e+00
Intelligence All.MultiPRS SBLUP.Inf 0.102 0.099 0.003 6.65e-01 0.097 0.094 0.004 2.57e-01
Intelligence LDpred1.Inf SBLUP.Inf 0.099 0.099 -0.001 4.75e-01 0.094 0.094 0.000 9.81e-01
Intelligence LDpred2.Inf SBLUP.Inf 0.099 0.099 0.000 8.40e-01 0.094 0.094 0.001 1.42e-01
Intelligence DBSLMM.PseudoVal SBLUP.Inf 0.090 0.099 -0.009 4.11e-04 0.082 0.094 -0.012 1.98e-02
Intelligence lassosum.PseudoVal SBLUP.Inf 0.064 0.099 -0.035 2.11e-12 0.055 0.094 -0.039 7.96e-05
Intelligence LDpred2.MultiPRS SBLUP.Inf 0.103 0.099 0.004 6.00e-01 0.098 0.094 0.004 2.20e-01
Intelligence pT+clump.10FCVal SBLUP.Inf 0.084 0.099 -0.015 7.46e-07 0.074 0.094 -0.020 1.45e-03
Intelligence lassosum.10FCVal SBLUP.Inf 0.098 0.099 -0.001 5.75e-01 0.096 0.094 0.002 5.42e-01
Intelligence LDpred2.10FCVal SBLUP.Inf 0.102 0.099 0.003 4.24e-02 0.095 0.094 0.002 4.51e-01
Intelligence SBayesR.PseudoVal SBLUP.Inf 0.100 0.099 0.001 7.09e-01 0.090 0.094 -0.003 3.59e-01
Intelligence LDpred1.MultiPRS SBLUP.Inf 0.101 0.099 0.002 8.21e-01 0.094 0.094 0.001 8.14e-01
Intelligence LDpred2.PseudoVal SBLUP.Inf 0.100 0.099 0.001 2.27e-02 0.095 0.094 0.002 8.13e-02
Intelligence SBLUP.Inf SBLUP.Inf 0.099 0.099 0.000 1.00e+00 0.094 0.094 0.000 1.00e+00
Intelligence pT+clump.MultiPRS SBLUP.Inf 0.087 0.099 -0.013 7.37e-02 0.081 0.094 -0.012 4.41e-02
Intelligence lassosum.MultiPRS SBLUP.Inf 0.102 0.099 0.003 7.03e-01 0.099 0.094 0.005 1.00e-01
Intelligence LDpred1.10FCVal SBLUP.Inf 0.100 0.099 0.001 3.15e-01 0.094 0.094 0.000 9.18e-01
Height lassosum.10FCVal All.MultiPRS 0.347 0.360 -0.013 4.14e-02 0.340 0.356 -0.016 8.37e-10
Height All.MultiPRS All.MultiPRS 0.360 0.360 0.000 1.00e+00 0.356 0.356 0.000 1.00e+00
Height DBSLMM.PseudoVal All.MultiPRS 0.333 0.360 -0.026 4.12e-05 0.324 0.356 -0.032 1.48e-17
Height LDpred1.Inf All.MultiPRS 0.297 0.360 -0.063 3.97e-22 0.295 0.356 -0.061 1.51e-27
Height LDpred2.Inf All.MultiPRS 0.302 0.360 -0.058 5.40e-19 0.299 0.356 -0.056 1.07e-25
Height lassosum.MultiPRS All.MultiPRS 0.349 0.360 -0.010 1.12e-01 0.343 0.356 -0.013 1.05e-07
Height LDpred1.10FCVal All.MultiPRS 0.287 0.360 -0.073 2.27e-29 0.288 0.356 -0.067 7.25e-29
Height pT+clump.MultiPRS All.MultiPRS 0.320 0.360 -0.040 4.95e-10 0.314 0.356 -0.042 2.27e-20
Height LDpred2.MultiPRS All.MultiPRS 0.356 0.360 -0.004 2.18e-07 0.351 0.356 -0.004 4.46e-03
Height pT+clump.10FCVal All.MultiPRS 0.305 0.360 -0.055 1.31e-17 0.299 0.356 -0.057 2.13e-26
Height lassosum.PseudoVal All.MultiPRS 0.281 0.360 -0.078 1.68e-33 0.276 0.356 -0.080 6.46e-38
Height LDpred2.10FCVal All.MultiPRS 0.351 0.360 -0.008 1.84e-01 0.343 0.356 -0.012 2.80e-08
Height SBayesR.PseudoVal All.MultiPRS 0.342 0.360 -0.018 4.95e-03 0.335 0.356 -0.021 3.39e-11
Height LDpred1.MultiPRS All.MultiPRS 0.304 0.360 -0.055 1.47e-17 0.303 0.356 -0.053 1.45e-24
Height LDpred2.PseudoVal All.MultiPRS 0.335 0.360 -0.024 1.43e-04 0.326 0.356 -0.029 2.29e-16
Height SBLUP.Inf All.MultiPRS 0.295 0.360 -0.064 3.07e-23 0.292 0.356 -0.064 6.29e-30
Height LDpred2.MultiPRS DBSLMM.PseudoVal 0.356 0.333 0.022 4.71e-04 0.351 0.324 0.027 2.22e-13
Height pT+clump.10FCVal DBSLMM.PseudoVal 0.305 0.333 -0.029 1.05e-19 0.299 0.324 -0.025 8.71e-05
Height lassosum.10FCVal DBSLMM.PseudoVal 0.347 0.333 0.013 2.21e-11 0.340 0.324 0.016 9.25e-05
Height All.MultiPRS DBSLMM.PseudoVal 0.360 0.333 0.026 4.12e-05 0.356 0.324 0.032 1.48e-17
Height LDpred1.MultiPRS DBSLMM.PseudoVal 0.304 0.333 -0.029 8.32e-06 0.303 0.324 -0.021 1.06e-08
Height LDpred2.PseudoVal DBSLMM.PseudoVal 0.335 0.333 0.002 2.31e-01 0.326 0.324 0.002 4.78e-01
Height DBSLMM.PseudoVal DBSLMM.PseudoVal 0.333 0.333 0.000 1.00e+00 0.324 0.324 0.000 1.00e+00
Height LDpred1.Inf DBSLMM.PseudoVal 0.297 0.333 -0.036 9.92e-84 0.295 0.324 -0.029 1.36e-14
Height LDpred2.Inf DBSLMM.PseudoVal 0.302 0.333 -0.031 5.87e-65 0.299 0.324 -0.025 1.98e-11
Height lassosum.MultiPRS DBSLMM.PseudoVal 0.349 0.333 0.016 1.22e-02 0.343 0.324 0.019 8.74e-08
Height LDpred1.10FCVal DBSLMM.PseudoVal 0.287 0.333 -0.047 5.70e-105 0.288 0.324 -0.036 1.75e-16
Height pT+clump.MultiPRS DBSLMM.PseudoVal 0.320 0.333 -0.014 3.32e-02 0.314 0.324 -0.010 3.26e-02
Height SBayesR.PseudoVal DBSLMM.PseudoVal 0.342 0.333 0.008 4.55e-09 0.335 0.324 0.011 9.59e-05
Height lassosum.PseudoVal DBSLMM.PseudoVal 0.281 0.333 -0.052 1.35e-42 0.276 0.324 -0.048 2.73e-10
Height LDpred2.10FCVal DBSLMM.PseudoVal 0.351 0.333 0.018 3.89e-24 0.343 0.324 0.019 4.79e-08
Height SBLUP.Inf DBSLMM.PseudoVal 0.295 0.333 -0.038 1.63e-95 0.292 0.324 -0.032 2.32e-18
Height All.MultiPRS lassosum.MultiPRS 0.360 0.349 0.010 1.12e-01 0.356 0.343 0.013 1.05e-07
Height LDpred1.MultiPRS lassosum.MultiPRS 0.304 0.349 -0.045 2.29e-71 0.303 0.343 -0.040 2.80e-15
Height LDpred1.Inf lassosum.MultiPRS 0.297 0.349 -0.052 7.65e-16 0.295 0.343 -0.048 1.05e-18
Height LDpred2.Inf lassosum.MultiPRS 0.302 0.349 -0.047 3.02e-13 0.299 0.343 -0.044 2.93e-16
Height lassosum.MultiPRS lassosum.MultiPRS 0.349 0.349 0.000 1.00e+00 0.343 0.343 0.000 1.00e+00
Height DBSLMM.PseudoVal lassosum.MultiPRS 0.333 0.349 -0.016 1.22e-02 0.324 0.343 -0.019 8.74e-08
Height lassosum.10FCVal lassosum.MultiPRS 0.347 0.349 -0.003 6.56e-01 0.340 0.343 -0.003 1.84e-02
Height LDpred2.MultiPRS lassosum.MultiPRS 0.356 0.349 0.006 3.23e-01 0.351 0.343 0.009 1.96e-03
Height pT+clump.10FCVal lassosum.MultiPRS 0.305 0.349 -0.045 3.42e-12 0.299 0.343 -0.044 5.98e-16
Height lassosum.PseudoVal lassosum.MultiPRS 0.281 0.349 -0.068 8.05e-26 0.276 0.343 -0.067 6.10e-30
Height LDpred2.10FCVal lassosum.MultiPRS 0.351 0.349 0.002 7.89e-01 0.343 0.343 0.000 8.89e-01
Height SBayesR.PseudoVal lassosum.MultiPRS 0.342 0.349 -0.008 2.25e-01 0.335 0.343 -0.008 2.32e-02
Height LDpred2.PseudoVal lassosum.MultiPRS 0.335 0.349 -0.014 2.73e-02 0.326 0.343 -0.017 5.78e-05
Height SBLUP.Inf lassosum.MultiPRS 0.295 0.349 -0.054 8.80e-17 0.292 0.343 -0.051 6.23e-21
Height pT+clump.MultiPRS lassosum.MultiPRS 0.320 0.349 -0.030 3.54e-06 0.314 0.343 -0.029 3.64e-11
Height LDpred1.10FCVal lassosum.MultiPRS 0.287 0.349 -0.063 5.99e-22 0.288 0.343 -0.055 7.32e-21
Height All.MultiPRS lassosum.10FCVal 0.360 0.347 0.013 4.14e-02 0.356 0.340 0.016 8.37e-10
Height LDpred1.MultiPRS lassosum.10FCVal 0.304 0.347 -0.042 6.77e-11 0.303 0.340 -0.037 4.73e-12
Height LDpred2.PseudoVal lassosum.10FCVal 0.335 0.347 -0.011 7.05e-08 0.326 0.340 -0.013 1.72e-03
Height DBSLMM.PseudoVal lassosum.10FCVal 0.333 0.347 -0.013 2.21e-11 0.324 0.340 -0.016 9.25e-05
Height LDpred1.Inf lassosum.10FCVal 0.297 0.347 -0.050 2.04e-69 0.295 0.340 -0.045 5.72e-15
Height LDpred2.Inf lassosum.10FCVal 0.302 0.347 -0.045 1.11e-57 0.299 0.340 -0.040 8.17e-13
Height lassosum.MultiPRS lassosum.10FCVal 0.349 0.347 0.003 6.56e-01 0.343 0.340 0.003 1.84e-02
Height LDpred1.10FCVal lassosum.10FCVal 0.287 0.347 -0.060 2.53e-89 0.288 0.340 -0.051 3.56e-17
Height lassosum.10FCVal lassosum.10FCVal 0.347 0.347 0.000 1.00e+00 0.340 0.340 0.000 1.00e+00
Height LDpred2.MultiPRS lassosum.10FCVal 0.356 0.347 0.009 1.51e-01 0.351 0.340 0.012 3.24e-05
Height pT+clump.10FCVal lassosum.10FCVal 0.305 0.347 -0.042 1.75e-51 0.299 0.340 -0.041 4.20e-13
Height lassosum.PseudoVal lassosum.10FCVal 0.281 0.347 -0.065 8.97e-111 0.276 0.340 -0.064 9.46e-28
Height LDpred2.10FCVal lassosum.10FCVal 0.351 0.347 0.005 3.60e-03 0.343 0.340 0.004 2.42e-01
Height SBayesR.PseudoVal lassosum.10FCVal 0.342 0.347 -0.005 6.81e-03 0.335 0.340 -0.005 2.16e-01
Height SBLUP.Inf lassosum.10FCVal 0.295 0.347 -0.051 1.25e-73 0.292 0.340 -0.048 7.40e-17
Height pT+clump.MultiPRS lassosum.10FCVal 0.320 0.347 -0.027 2.82e-05 0.314 0.340 -0.026 6.71e-09
Height All.MultiPRS lassosum.PseudoVal 0.360 0.281 0.078 1.68e-33 0.356 0.276 0.080 6.46e-38
Height LDpred1.MultiPRS lassosum.PseudoVal 0.304 0.281 0.023 4.91e-04 0.303 0.276 0.027 3.06e-03
Height LDpred1.Inf lassosum.PseudoVal 0.297 0.281 0.016 7.29e-04 0.295 0.276 0.019 3.86e-02
Height LDpred2.Inf lassosum.PseudoVal 0.302 0.281 0.021 6.88e-06 0.299 0.276 0.024 1.08e-02
Height lassosum.MultiPRS lassosum.PseudoVal 0.349 0.281 0.068 8.05e-26 0.343 0.276 0.067 6.10e-30
Height DBSLMM.PseudoVal lassosum.PseudoVal 0.333 0.281 0.052 1.35e-42 0.324 0.276 0.048 2.73e-10
Height lassosum.10FCVal lassosum.PseudoVal 0.347 0.281 0.065 8.97e-111 0.340 0.276 0.064 9.46e-28
Height LDpred2.MultiPRS lassosum.PseudoVal 0.356 0.281 0.074 2.28e-30 0.351 0.276 0.076 5.30e-29
Height pT+clump.10FCVal lassosum.PseudoVal 0.305 0.281 0.023 7.20e-11 0.299 0.276 0.023 1.16e-03
Height lassosum.PseudoVal lassosum.PseudoVal 0.281 0.281 0.000 1.00e+00 0.276 0.276 0.000 1.00e+00
Height LDpred2.10FCVal lassosum.PseudoVal 0.351 0.281 0.070 3.04e-77 0.343 0.276 0.068 3.38e-19
Height SBayesR.PseudoVal lassosum.PseudoVal 0.342 0.281 0.060 1.86e-52 0.335 0.276 0.059 7.44e-14
Height LDpred2.PseudoVal lassosum.PseudoVal 0.335 0.281 0.054 3.02e-37 0.326 0.276 0.051 2.86e-09
Height SBLUP.Inf lassosum.PseudoVal 0.295 0.281 0.014 2.77e-03 0.292 0.276 0.016 8.48e-02
Height pT+clump.MultiPRS lassosum.PseudoVal 0.320 0.281 0.038 6.27e-09 0.314 0.276 0.038 6.25e-08
Height LDpred1.10FCVal lassosum.PseudoVal 0.287 0.281 0.005 2.61e-01 0.288 0.276 0.013 1.84e-01
Height DBSLMM.PseudoVal LDpred1.MultiPRS 0.333 0.304 0.029 8.32e-06 0.324 0.303 0.021 1.06e-08
Height LDpred2.MultiPRS LDpred1.MultiPRS 0.356 0.304 0.052 2.19e-15 0.351 0.303 0.049 6.12e-24
Height pT+clump.10FCVal LDpred1.MultiPRS 0.305 0.304 0.000 9.73e-01 0.299 0.303 -0.004 6.31e-01
Height lassosum.PseudoVal LDpred1.MultiPRS 0.281 0.304 -0.023 4.91e-04 0.276 0.303 -0.027 3.06e-03
Height lassosum.10FCVal LDpred1.MultiPRS 0.347 0.304 0.042 6.77e-11 0.340 0.303 0.037 4.73e-12
Height All.MultiPRS LDpred1.MultiPRS 0.360 0.304 0.055 1.47e-17 0.356 0.303 0.053 1.45e-24
Height LDpred1.MultiPRS LDpred1.MultiPRS 0.304 0.304 0.000 1.00e+00 0.303 0.303 0.000 1.00e+00
Height LDpred2.PseudoVal LDpred1.MultiPRS 0.335 0.304 0.031 1.98e-06 0.326 0.303 0.024 5.93e-14
Height SBLUP.Inf LDpred1.MultiPRS 0.295 0.304 -0.009 1.77e-01 0.292 0.303 -0.011 3.62e-05
Height LDpred1.Inf LDpred1.MultiPRS 0.297 0.304 -0.007 2.73e-01 0.295 0.303 -0.007 5.76e-04
Height LDpred2.Inf LDpred1.MultiPRS 0.302 0.304 -0.002 7.41e-01 0.299 0.303 -0.003 2.20e-01
Height lassosum.MultiPRS LDpred1.MultiPRS 0.349 0.304 0.045 2.29e-71 0.343 0.303 0.040 2.80e-15
Height LDpred1.10FCVal LDpred1.MultiPRS 0.287 0.304 -0.018 7.78e-03 0.288 0.303 -0.014 1.50e-05
Height pT+clump.MultiPRS LDpred1.MultiPRS 0.320 0.304 0.015 1.96e-02 0.314 0.303 0.011 6.22e-02
Height SBayesR.PseudoVal LDpred1.MultiPRS 0.342 0.304 0.037 9.02e-09 0.335 0.303 0.033 2.05e-21
Height LDpred2.10FCVal LDpred1.MultiPRS 0.351 0.304 0.047 4.72e-13 0.343 0.303 0.041 1.70e-21
Height All.MultiPRS LDpred1.Inf 0.360 0.297 0.063 3.97e-22 0.356 0.295 0.061 1.51e-27
Height LDpred1.Inf LDpred1.Inf 0.297 0.297 0.000 1.00e+00 0.295 0.295 0.000 1.00e+00
Height LDpred2.Inf LDpred1.Inf 0.302 0.297 0.005 1.76e-10 0.299 0.295 0.004 5.96e-03
Height DBSLMM.PseudoVal LDpred1.Inf 0.333 0.297 0.036 9.92e-84 0.324 0.295 0.029 1.36e-14
Height lassosum.10FCVal LDpred1.Inf 0.347 0.297 0.050 2.04e-69 0.340 0.295 0.045 5.72e-15
Height LDpred2.MultiPRS LDpred1.Inf 0.356 0.297 0.059 1.24e-19 0.351 0.295 0.056 9.59e-27
Height pT+clump.10FCVal LDpred1.Inf 0.305 0.297 0.007 5.75e-02 0.299 0.295 0.004 6.35e-01
Height lassosum.PseudoVal LDpred1.Inf 0.281 0.297 -0.016 7.29e-04 0.276 0.295 -0.019 3.86e-02
Height LDpred2.10FCVal LDpred1.Inf 0.351 0.297 0.054 1.34e-120 0.343 0.295 0.048 3.39e-25
Height SBayesR.PseudoVal LDpred1.Inf 0.342 0.297 0.045 4.07e-136 0.335 0.295 0.040 2.27e-28
Height LDpred1.MultiPRS LDpred1.Inf 0.304 0.297 0.007 2.73e-01 0.303 0.295 0.007 5.76e-04
Height LDpred2.PseudoVal LDpred1.Inf 0.335 0.297 0.038 2.99e-119 0.326 0.295 0.031 3.20e-21
Height SBLUP.Inf LDpred1.Inf 0.295 0.297 -0.002 3.31e-02 0.292 0.295 -0.003 4.65e-02
Height pT+clump.MultiPRS LDpred1.Inf 0.320 0.297 0.023 6.01e-04 0.314 0.295 0.019 2.57e-03
Height lassosum.MultiPRS LDpred1.Inf 0.349 0.297 0.052 7.65e-16 0.343 0.295 0.048 1.05e-18
Height LDpred1.10FCVal LDpred1.Inf 0.287 0.297 -0.010 5.90e-16 0.288 0.295 -0.007 1.02e-02
Height LDpred1.Inf LDpred1.10FCVal 0.297 0.287 0.010 5.90e-16 0.295 0.288 0.007 1.02e-02
Height DBSLMM.PseudoVal LDpred1.10FCVal 0.333 0.287 0.047 5.70e-105 0.324 0.288 0.036 1.75e-16
Height lassosum.10FCVal LDpred1.10FCVal 0.347 0.287 0.060 2.53e-89 0.340 0.288 0.051 3.56e-17
Height LDpred2.MultiPRS LDpred1.10FCVal 0.356 0.287 0.069 1.86e-26 0.351 0.288 0.063 1.43e-28
Height pT+clump.10FCVal LDpred1.10FCVal 0.305 0.287 0.018 1.21e-05 0.299 0.288 0.010 2.05e-01
Height lassosum.PseudoVal LDpred1.10FCVal 0.281 0.287 -0.005 2.61e-01 0.276 0.288 -0.013 1.84e-01
Height LDpred2.10FCVal LDpred1.10FCVal 0.351 0.287 0.065 1.97e-143 0.343 0.288 0.055 5.93e-27
Height All.MultiPRS LDpred1.10FCVal 0.360 0.287 0.073 2.27e-29 0.356 0.288 0.067 7.25e-29
Height LDpred1.MultiPRS LDpred1.10FCVal 0.304 0.287 0.018 7.78e-03 0.303 0.288 0.014 1.50e-05
Height LDpred2.PseudoVal LDpred1.10FCVal 0.335 0.287 0.049 1.15e-139 0.326 0.288 0.038 2.46e-22
Height SBLUP.Inf LDpred1.10FCVal 0.295 0.287 0.009 1.86e-11 0.292 0.288 0.004 1.74e-01
Height pT+clump.MultiPRS LDpred1.10FCVal 0.320 0.287 0.033 5.53e-07 0.314 0.288 0.025 1.23e-04
Height LDpred2.Inf LDpred1.10FCVal 0.302 0.287 0.015 1.44e-30 0.299 0.288 0.011 5.01e-05
Height lassosum.MultiPRS LDpred1.10FCVal 0.349 0.287 0.063 5.99e-22 0.343 0.288 0.055 7.32e-21
Height LDpred1.10FCVal LDpred1.10FCVal 0.287 0.287 0.000 1.00e+00 0.288 0.288 0.000 1.00e+00
Height SBayesR.PseudoVal LDpred1.10FCVal 0.342 0.287 0.055 2.65e-154 0.335 0.288 0.047 2.46e-28
Height LDpred2.MultiPRS LDpred2.MultiPRS 0.356 0.356 0.000 1.00e+00 0.351 0.351 0.000 1.00e+00
Height lassosum.10FCVal LDpred2.MultiPRS 0.347 0.356 -0.009 1.51e-01 0.340 0.351 -0.012 3.24e-05
Height All.MultiPRS LDpred2.MultiPRS 0.360 0.356 0.004 2.18e-07 0.356 0.351 0.004 4.46e-03
Height LDpred1.MultiPRS LDpred2.MultiPRS 0.304 0.356 -0.052 2.19e-15 0.303 0.351 -0.049 6.12e-24
Height DBSLMM.PseudoVal LDpred2.MultiPRS 0.333 0.356 -0.022 4.71e-04 0.324 0.351 -0.027 2.22e-13
Height LDpred1.Inf LDpred2.MultiPRS 0.297 0.356 -0.059 1.24e-19 0.295 0.351 -0.056 9.59e-27
Height LDpred2.Inf LDpred2.MultiPRS 0.302 0.356 -0.054 1.05e-16 0.299 0.351 -0.052 1.14e-24
Height lassosum.MultiPRS LDpred2.MultiPRS 0.349 0.356 -0.006 3.23e-01 0.343 0.351 -0.009 1.96e-03
Height LDpred1.10FCVal LDpred2.MultiPRS 0.287 0.356 -0.069 1.86e-26 0.288 0.351 -0.063 1.43e-28
Height pT+clump.MultiPRS LDpred2.MultiPRS 0.320 0.356 -0.036 1.94e-08 0.314 0.351 -0.038 1.20e-15
Height SBayesR.PseudoVal LDpred2.MultiPRS 0.342 0.356 -0.014 2.74e-02 0.335 0.351 -0.016 7.51e-10
Height pT+clump.10FCVal LDpred2.MultiPRS 0.305 0.356 -0.051 2.05e-15 0.299 0.351 -0.053 2.82e-19
Height lassosum.PseudoVal LDpred2.MultiPRS 0.281 0.356 -0.074 2.28e-30 0.276 0.351 -0.076 5.30e-29
Height LDpred2.10FCVal LDpred2.MultiPRS 0.351 0.356 -0.005 4.69e-01 0.343 0.351 -0.008 4.00e-08
Height LDpred2.PseudoVal LDpred2.MultiPRS 0.335 0.356 -0.020 1.39e-03 0.326 0.351 -0.025 1.76e-16
Height SBLUP.Inf LDpred2.MultiPRS 0.295 0.356 -0.060 1.10e-20 0.292 0.351 -0.059 1.79e-29
Height LDpred2.MultiPRS LDpred2.10FCVal 0.356 0.351 0.005 4.69e-01 0.351 0.343 0.008 4.00e-08
Height pT+clump.10FCVal LDpred2.10FCVal 0.305 0.351 -0.047 1.14e-51 0.299 0.343 -0.045 1.32e-12
Height lassosum.10FCVal LDpred2.10FCVal 0.347 0.351 -0.005 3.60e-03 0.340 0.343 -0.004 2.42e-01
Height All.MultiPRS LDpred2.10FCVal 0.360 0.351 0.008 1.84e-01 0.356 0.343 0.012 2.80e-08
Height LDpred1.MultiPRS LDpred2.10FCVal 0.304 0.351 -0.047 4.72e-13 0.303 0.343 -0.041 1.70e-21
Height LDpred2.PseudoVal LDpred2.10FCVal 0.335 0.351 -0.016 4.79e-51 0.326 0.343 -0.017 6.38e-16
Height DBSLMM.PseudoVal LDpred2.10FCVal 0.333 0.351 -0.018 3.89e-24 0.324 0.343 -0.019 4.79e-08
Height LDpred1.Inf LDpred2.10FCVal 0.297 0.351 -0.054 1.34e-120 0.295 0.343 -0.048 3.39e-25
Height LDpred2.Inf LDpred2.10FCVal 0.302 0.351 -0.049 6.45e-109 0.299 0.343 -0.044 3.82e-23
Height lassosum.MultiPRS LDpred2.10FCVal 0.349 0.351 -0.002 7.89e-01 0.343 0.343 0.000 8.89e-01
Height LDpred1.10FCVal LDpred2.10FCVal 0.287 0.351 -0.065 1.97e-143 0.288 0.343 -0.055 5.93e-27
Height pT+clump.MultiPRS LDpred2.10FCVal 0.320 0.351 -0.032 9.45e-07 0.314 0.343 -0.030 1.69e-09
Height SBayesR.PseudoVal LDpred2.10FCVal 0.342 0.351 -0.009 1.27e-18 0.335 0.343 -0.008 1.26e-04
Height lassosum.PseudoVal LDpred2.10FCVal 0.281 0.351 -0.070 3.04e-77 0.276 0.343 -0.068 3.38e-19
Height LDpred2.10FCVal LDpred2.10FCVal 0.351 0.351 0.000 1.00e+00 0.343 0.343 0.000 1.00e+00
Height SBLUP.Inf LDpred2.10FCVal 0.295 0.351 -0.056 1.43e-129 0.292 0.343 -0.051 1.05e-28
Height LDpred2.MultiPRS LDpred2.PseudoVal 0.356 0.335 0.020 1.39e-03 0.351 0.326 0.025 1.76e-16
Height lassosum.10FCVal LDpred2.PseudoVal 0.347 0.335 0.011 7.05e-08 0.340 0.326 0.013 1.72e-03
Height All.MultiPRS LDpred2.PseudoVal 0.360 0.335 0.024 1.43e-04 0.356 0.326 0.029 2.29e-16
Height LDpred1.MultiPRS LDpred2.PseudoVal 0.304 0.335 -0.031 1.98e-06 0.303 0.326 -0.024 5.93e-14
Height DBSLMM.PseudoVal LDpred2.PseudoVal 0.333 0.335 -0.002 2.31e-01 0.324 0.326 -0.002 4.78e-01
Height LDpred1.Inf LDpred2.PseudoVal 0.297 0.335 -0.038 2.99e-119 0.295 0.326 -0.031 3.20e-21
Height LDpred2.Inf LDpred2.PseudoVal 0.302 0.335 -0.033 6.08e-109 0.299 0.326 -0.027 3.36e-19
Height lassosum.MultiPRS LDpred2.PseudoVal 0.349 0.335 0.014 2.73e-02 0.343 0.326 0.017 5.78e-05
Height LDpred1.10FCVal LDpred2.PseudoVal 0.287 0.335 -0.049 1.15e-139 0.288 0.326 -0.038 2.46e-22
Height pT+clump.MultiPRS LDpred2.PseudoVal 0.320 0.335 -0.016 1.52e-02 0.314 0.326 -0.013 2.36e-02
Height SBayesR.PseudoVal LDpred2.PseudoVal 0.342 0.335 0.006 1.74e-10 0.335 0.326 0.009 1.32e-05
Height pT+clump.10FCVal LDpred2.PseudoVal 0.305 0.335 -0.031 4.62e-18 0.299 0.326 -0.027 1.40e-04
Height lassosum.PseudoVal LDpred2.PseudoVal 0.281 0.335 -0.054 3.02e-37 0.276 0.326 -0.051 2.86e-09
Height LDpred2.10FCVal LDpred2.PseudoVal 0.351 0.335 0.016 4.79e-51 0.343 0.326 0.017 6.38e-16
Height LDpred2.PseudoVal LDpred2.PseudoVal 0.335 0.335 0.000 1.00e+00 0.326 0.326 0.000 1.00e+00
Height SBLUP.Inf LDpred2.PseudoVal 0.295 0.335 -0.040 5.39e-142 0.292 0.326 -0.034 1.72e-27
Height DBSLMM.PseudoVal LDpred2.Inf 0.333 0.302 0.031 5.87e-65 0.324 0.299 0.025 1.98e-11
Height LDpred2.MultiPRS LDpred2.Inf 0.356 0.302 0.054 1.05e-16 0.351 0.299 0.052 1.14e-24
Height pT+clump.10FCVal LDpred2.Inf 0.305 0.302 0.002 5.44e-01 0.299 0.299 -0.001 9.45e-01
Height lassosum.PseudoVal LDpred2.Inf 0.281 0.302 -0.021 6.88e-06 0.276 0.299 -0.024 1.08e-02
Height lassosum.10FCVal LDpred2.Inf 0.347 0.302 0.045 1.11e-57 0.340 0.299 0.040 8.17e-13
Height All.MultiPRS LDpred2.Inf 0.360 0.302 0.058 5.40e-19 0.356 0.299 0.056 1.07e-25
Height LDpred1.MultiPRS LDpred2.Inf 0.304 0.302 0.002 7.41e-01 0.303 0.299 0.003 2.20e-01
Height LDpred2.PseudoVal LDpred2.Inf 0.335 0.302 0.033 6.08e-109 0.326 0.299 0.027 3.36e-19
Height SBLUP.Inf LDpred2.Inf 0.295 0.302 -0.007 9.77e-28 0.292 0.299 -0.007 2.22e-09
Height LDpred1.Inf LDpred2.Inf 0.297 0.302 -0.005 1.76e-10 0.295 0.299 -0.004 5.96e-03
Height LDpred2.Inf LDpred2.Inf 0.302 0.302 0.000 1.00e+00 0.299 0.299 0.000 1.00e+00
Height lassosum.MultiPRS LDpred2.Inf 0.349 0.302 0.047 3.02e-13 0.343 0.299 0.044 2.93e-16
Height LDpred1.10FCVal LDpred2.Inf 0.287 0.302 -0.015 1.44e-30 0.288 0.299 -0.011 5.01e-05
Height pT+clump.MultiPRS LDpred2.Inf 0.320 0.302 0.017 7.72e-03 0.314 0.299 0.014 2.19e-02
Height SBayesR.PseudoVal LDpred2.Inf 0.342 0.302 0.040 3.63e-112 0.335 0.299 0.036 6.09e-24
Height LDpred2.10FCVal LDpred2.Inf 0.351 0.302 0.049 6.45e-109 0.343 0.299 0.044 3.82e-23
Height All.MultiPRS pT+clump.MultiPRS 0.360 0.320 0.040 4.95e-10 0.356 0.314 0.042 2.27e-20
Height LDpred1.MultiPRS pT+clump.MultiPRS 0.304 0.320 -0.015 1.96e-02 0.303 0.314 -0.011 6.22e-02
Height LDpred2.PseudoVal pT+clump.MultiPRS 0.335 0.320 0.016 1.52e-02 0.326 0.314 0.013 2.36e-02
Height DBSLMM.PseudoVal pT+clump.MultiPRS 0.333 0.320 0.014 3.32e-02 0.324 0.314 0.010 3.26e-02
Height LDpred1.Inf pT+clump.MultiPRS 0.297 0.320 -0.023 6.01e-04 0.295 0.314 -0.019 2.57e-03
Height LDpred2.Inf pT+clump.MultiPRS 0.302 0.320 -0.017 7.72e-03 0.299 0.314 -0.014 2.19e-02
Height lassosum.MultiPRS pT+clump.MultiPRS 0.349 0.320 0.030 3.54e-06 0.343 0.314 0.029 3.64e-11
Height LDpred1.10FCVal pT+clump.MultiPRS 0.287 0.320 -0.033 5.53e-07 0.288 0.314 -0.025 1.23e-04
Height lassosum.10FCVal pT+clump.MultiPRS 0.347 0.320 0.027 2.82e-05 0.340 0.314 0.026 6.71e-09
Height LDpred2.MultiPRS pT+clump.MultiPRS 0.356 0.320 0.036 1.94e-08 0.351 0.314 0.038 1.20e-15
Height pT+clump.10FCVal pT+clump.MultiPRS 0.305 0.320 -0.015 2.17e-02 0.299 0.314 -0.015 4.59e-07
Height lassosum.PseudoVal pT+clump.MultiPRS 0.281 0.320 -0.038 6.27e-09 0.276 0.314 -0.038 6.25e-08
Height LDpred2.10FCVal pT+clump.MultiPRS 0.351 0.320 0.032 9.45e-07 0.343 0.314 0.030 1.69e-09
Height SBayesR.PseudoVal pT+clump.MultiPRS 0.342 0.320 0.022 6.23e-04 0.335 0.314 0.021 7.74e-06
Height SBLUP.Inf pT+clump.MultiPRS 0.295 0.320 -0.024 2.27e-04 0.292 0.314 -0.022 4.55e-04
Height pT+clump.MultiPRS pT+clump.MultiPRS 0.320 0.320 0.000 1.00e+00 0.314 0.314 0.000 1.00e+00
Height lassosum.10FCVal pT+clump.10FCVal 0.347 0.305 0.042 1.75e-51 0.340 0.299 0.041 4.20e-13
Height All.MultiPRS pT+clump.10FCVal 0.360 0.305 0.055 1.31e-17 0.356 0.299 0.057 2.13e-26
Height DBSLMM.PseudoVal pT+clump.10FCVal 0.333 0.305 0.029 1.05e-19 0.324 0.299 0.025 8.71e-05
Height LDpred1.Inf pT+clump.10FCVal 0.297 0.305 -0.007 5.75e-02 0.295 0.299 -0.004 6.35e-01
Height LDpred2.Inf pT+clump.10FCVal 0.302 0.305 -0.002 5.44e-01 0.299 0.299 0.001 9.45e-01
Height lassosum.MultiPRS pT+clump.10FCVal 0.349 0.305 0.045 3.42e-12 0.343 0.299 0.044 5.98e-16
Height LDpred1.10FCVal pT+clump.10FCVal 0.287 0.305 -0.018 1.21e-05 0.288 0.299 -0.010 2.05e-01
Height pT+clump.MultiPRS pT+clump.10FCVal 0.320 0.305 0.015 2.17e-02 0.314 0.299 0.015 4.59e-07
Height LDpred2.MultiPRS pT+clump.10FCVal 0.356 0.305 0.051 2.05e-15 0.351 0.299 0.053 2.82e-19
Height pT+clump.10FCVal pT+clump.10FCVal 0.305 0.305 0.000 1.00e+00 0.299 0.299 0.000 1.00e+00
Height lassosum.PseudoVal pT+clump.10FCVal 0.281 0.305 -0.023 7.20e-11 0.276 0.299 -0.023 1.16e-03
Height LDpred2.10FCVal pT+clump.10FCVal 0.351 0.305 0.047 1.14e-51 0.343 0.299 0.045 1.32e-12
Height SBayesR.PseudoVal pT+clump.10FCVal 0.342 0.305 0.037 1.69e-31 0.335 0.299 0.036 1.46e-08
Height LDpred1.MultiPRS pT+clump.10FCVal 0.304 0.305 0.000 9.73e-01 0.303 0.299 0.004 6.31e-01
Height LDpred2.PseudoVal pT+clump.10FCVal 0.335 0.305 0.031 4.62e-18 0.326 0.299 0.027 1.40e-04
Height SBLUP.Inf pT+clump.10FCVal 0.295 0.305 -0.009 2.11e-02 0.292 0.299 -0.007 3.89e-01
Height LDpred1.Inf SBayesR.PseudoVal 0.297 0.342 -0.045 4.07e-136 0.295 0.335 -0.040 2.27e-28
Height DBSLMM.PseudoVal SBayesR.PseudoVal 0.333 0.342 -0.008 4.55e-09 0.324 0.335 -0.011 9.59e-05
Height lassosum.10FCVal SBayesR.PseudoVal 0.347 0.342 0.005 6.81e-03 0.340 0.335 0.005 2.16e-01
Height LDpred2.MultiPRS SBayesR.PseudoVal 0.356 0.342 0.014 2.74e-02 0.351 0.335 0.016 7.51e-10
Height pT+clump.10FCVal SBayesR.PseudoVal 0.305 0.342 -0.037 1.69e-31 0.299 0.335 -0.036 1.46e-08
Height lassosum.PseudoVal SBayesR.PseudoVal 0.281 0.342 -0.060 1.86e-52 0.276 0.335 -0.059 7.44e-14
Height LDpred2.10FCVal SBayesR.PseudoVal 0.351 0.342 0.009 1.27e-18 0.343 0.335 0.008 1.26e-04
Height All.MultiPRS SBayesR.PseudoVal 0.360 0.342 0.018 4.95e-03 0.356 0.335 0.021 3.39e-11
Height LDpred1.MultiPRS SBayesR.PseudoVal 0.304 0.342 -0.037 9.02e-09 0.303 0.335 -0.033 2.05e-21
Height LDpred2.PseudoVal SBayesR.PseudoVal 0.335 0.342 -0.006 1.74e-10 0.326 0.335 -0.009 1.32e-05
Height SBLUP.Inf SBayesR.PseudoVal 0.295 0.342 -0.046 1.17e-145 0.292 0.335 -0.043 1.21e-32
Height pT+clump.MultiPRS SBayesR.PseudoVal 0.320 0.342 -0.022 6.23e-04 0.314 0.335 -0.021 7.74e-06
Height LDpred2.Inf SBayesR.PseudoVal 0.302 0.342 -0.040 3.63e-112 0.299 0.335 -0.036 6.09e-24
Height lassosum.MultiPRS SBayesR.PseudoVal 0.349 0.342 0.008 2.25e-01 0.343 0.335 0.008 2.32e-02
Height LDpred1.10FCVal SBayesR.PseudoVal 0.287 0.342 -0.055 2.65e-154 0.288 0.335 -0.047 2.46e-28
Height SBayesR.PseudoVal SBayesR.PseudoVal 0.342 0.342 0.000 1.00e+00 0.335 0.335 0.000 1.00e+00
Height All.MultiPRS SBLUP.Inf 0.360 0.295 0.064 3.07e-23 0.356 0.292 0.064 6.29e-30
Height LDpred1.Inf SBLUP.Inf 0.297 0.295 0.002 3.31e-02 0.295 0.292 0.003 4.65e-02
Height LDpred2.Inf SBLUP.Inf 0.302 0.295 0.007 9.77e-28 0.299 0.292 0.007 2.22e-09
Height DBSLMM.PseudoVal SBLUP.Inf 0.333 0.295 0.038 1.63e-95 0.324 0.292 0.032 2.32e-18
Height lassosum.10FCVal SBLUP.Inf 0.347 0.295 0.051 1.25e-73 0.340 0.292 0.048 7.40e-17
Height LDpred2.MultiPRS SBLUP.Inf 0.356 0.295 0.060 1.10e-20 0.351 0.292 0.059 1.79e-29
Height pT+clump.10FCVal SBLUP.Inf 0.305 0.295 0.009 2.11e-02 0.299 0.292 0.007 3.89e-01
Height lassosum.PseudoVal SBLUP.Inf 0.281 0.295 -0.014 2.77e-03 0.276 0.292 -0.016 8.48e-02
Height LDpred2.10FCVal SBLUP.Inf 0.351 0.295 0.056 1.43e-129 0.343 0.292 0.051 1.05e-28
Height SBayesR.PseudoVal SBLUP.Inf 0.342 0.295 0.046 1.17e-145 0.335 0.292 0.043 1.21e-32
Height LDpred1.MultiPRS SBLUP.Inf 0.304 0.295 0.009 1.77e-01 0.303 0.292 0.011 3.62e-05
Height LDpred2.PseudoVal SBLUP.Inf 0.335 0.295 0.040 5.39e-142 0.326 0.292 0.034 1.72e-27
Height SBLUP.Inf SBLUP.Inf 0.295 0.295 0.000 1.00e+00 0.292 0.292 0.000 1.00e+00
Height pT+clump.MultiPRS SBLUP.Inf 0.320 0.295 0.024 2.27e-04 0.314 0.292 0.022 4.55e-04
Height lassosum.MultiPRS SBLUP.Inf 0.349 0.295 0.054 8.80e-17 0.343 0.292 0.051 6.23e-21
Height LDpred1.10FCVal SBLUP.Inf 0.287 0.295 -0.009 1.86e-11 0.288 0.292 -0.004 1.74e-01
BMI lassosum.PseudoVal All.MultiPRS 0.211 0.308 -0.096 1.02e-46 0.220 0.308 -0.088 1.27e-30
BMI All.MultiPRS All.MultiPRS 0.308 0.308 0.000 1.00e+00 0.308 0.308 0.000 1.00e+00
BMI DBSLMM.PseudoVal All.MultiPRS 0.283 0.308 -0.025 1.48e-04 0.283 0.308 -0.025 1.61e-10
BMI LDpred1.Inf All.MultiPRS 0.272 0.308 -0.035 9.24e-08 0.264 0.308 -0.045 3.12e-21
BMI LDpred2.Inf All.MultiPRS 0.293 0.308 -0.015 2.14e-02 0.287 0.308 -0.021 1.94e-11
BMI lassosum.MultiPRS All.MultiPRS 0.305 0.308 -0.003 6.71e-01 0.308 0.308 -0.001 6.87e-01
BMI LDpred1.10FCVal All.MultiPRS 0.277 0.308 -0.031 2.30e-06 0.273 0.308 -0.036 8.40e-16
BMI pT+clump.MultiPRS All.MultiPRS 0.271 0.308 -0.037 1.76e-08 0.275 0.308 -0.033 2.01e-12
BMI LDpred2.MultiPRS All.MultiPRS 0.305 0.308 -0.002 4.49e-04 0.303 0.308 -0.005 1.92e-04
BMI pT+clump.10FCVal All.MultiPRS 0.248 0.308 -0.060 2.54e-19 0.245 0.308 -0.063 1.79e-26
BMI lassosum.10FCVal All.MultiPRS 0.300 0.308 -0.007 2.73e-01 0.300 0.308 -0.008 3.12e-04
BMI LDpred2.10FCVal All.MultiPRS 0.305 0.308 -0.003 6.46e-01 0.302 0.308 -0.006 3.17e-04
BMI SBayesR.PseudoVal All.MultiPRS 0.241 0.308 -0.066 2.45e-23 0.250 0.308 -0.058 6.71e-20
BMI LDpred1.MultiPRS All.MultiPRS 0.286 0.308 -0.022 8.15e-04 0.282 0.308 -0.026 6.09e-12
BMI LDpred2.PseudoVal All.MultiPRS 0.237 0.308 -0.070 5.88e-26 0.243 0.308 -0.065 3.77e-23
BMI SBLUP.Inf All.MultiPRS 0.292 0.308 -0.015 1.97e-02 0.287 0.308 -0.022 7.97e-12
BMI LDpred2.MultiPRS DBSLMM.PseudoVal 0.305 0.283 0.023 6.13e-04 0.303 0.283 0.020 5.43e-07
BMI pT+clump.10FCVal DBSLMM.PseudoVal 0.248 0.283 -0.035 1.05e-21 0.245 0.283 -0.038 2.53e-07
BMI lassosum.PseudoVal DBSLMM.PseudoVal 0.211 0.283 -0.071 3.32e-107 0.220 0.283 -0.063 5.43e-22
BMI All.MultiPRS DBSLMM.PseudoVal 0.308 0.283 0.025 1.48e-04 0.308 0.283 0.025 1.61e-10
BMI LDpred1.MultiPRS DBSLMM.PseudoVal 0.286 0.283 0.003 6.59e-01 0.282 0.283 -0.001 8.64e-01
BMI LDpred2.PseudoVal DBSLMM.PseudoVal 0.237 0.283 -0.045 4.54e-56 0.243 0.283 -0.040 5.39e-12
BMI DBSLMM.PseudoVal DBSLMM.PseudoVal 0.283 0.283 0.000 1.00e+00 0.283 0.283 0.000 1.00e+00
BMI LDpred1.Inf DBSLMM.PseudoVal 0.272 0.283 -0.010 1.97e-04 0.264 0.283 -0.019 7.19e-04
BMI LDpred2.Inf DBSLMM.PseudoVal 0.293 0.283 0.010 8.13e-05 0.287 0.283 0.004 4.05e-01
BMI lassosum.MultiPRS DBSLMM.PseudoVal 0.305 0.283 0.022 7.65e-04 0.308 0.283 0.025 7.44e-09
BMI LDpred1.10FCVal DBSLMM.PseudoVal 0.277 0.283 -0.006 3.64e-03 0.273 0.283 -0.010 1.70e-02
BMI pT+clump.MultiPRS DBSLMM.PseudoVal 0.271 0.283 -0.012 6.85e-02 0.275 0.283 -0.008 1.60e-01
BMI SBayesR.PseudoVal DBSLMM.PseudoVal 0.241 0.283 -0.041 2.84e-48 0.250 0.283 -0.033 6.28e-09
BMI lassosum.10FCVal DBSLMM.PseudoVal 0.300 0.283 0.018 1.91e-14 0.300 0.283 0.017 2.77e-04
BMI LDpred2.10FCVal DBSLMM.PseudoVal 0.305 0.283 0.022 1.39e-29 0.302 0.283 0.019 1.21e-06
BMI SBLUP.Inf DBSLMM.PseudoVal 0.292 0.283 0.010 1.07e-04 0.287 0.283 0.004 4.76e-01
BMI All.MultiPRS lassosum.MultiPRS 0.308 0.305 0.003 6.71e-01 0.308 0.308 0.001 6.87e-01
BMI LDpred1.MultiPRS lassosum.MultiPRS 0.286 0.305 -0.019 3.49e-03 0.282 0.308 -0.026 6.42e-10
BMI LDpred1.Inf lassosum.MultiPRS 0.272 0.305 -0.032 9.58e-07 0.264 0.308 -0.044 4.32e-19
BMI LDpred2.Inf lassosum.MultiPRS 0.293 0.305 -0.012 6.14e-02 0.287 0.308 -0.021 5.70e-09
BMI lassosum.MultiPRS lassosum.MultiPRS 0.305 0.305 0.000 1.00e+00 0.308 0.308 0.000 1.00e+00
BMI DBSLMM.PseudoVal lassosum.MultiPRS 0.283 0.305 -0.022 7.65e-04 0.283 0.308 -0.025 7.44e-09
BMI lassosum.PseudoVal lassosum.MultiPRS 0.211 0.305 -0.093 2.47e-44 0.220 0.308 -0.088 1.11e-30
BMI LDpred2.MultiPRS lassosum.MultiPRS 0.305 0.305 0.000 9.55e-01 0.303 0.308 -0.004 7.62e-02
BMI pT+clump.10FCVal lassosum.MultiPRS 0.248 0.305 -0.057 1.41e-17 0.245 0.308 -0.063 2.38e-27
BMI lassosum.10FCVal lassosum.MultiPRS 0.300 0.305 -0.004 5.04e-01 0.300 0.308 -0.008 8.54e-06
BMI LDpred2.10FCVal lassosum.MultiPRS 0.305 0.305 0.000 9.74e-01 0.302 0.308 -0.006 2.64e-02
BMI SBayesR.PseudoVal lassosum.MultiPRS 0.241 0.305 -0.063 1.90e-21 0.250 0.308 -0.058 3.34e-18
BMI LDpred2.PseudoVal lassosum.MultiPRS 0.237 0.305 -0.067 5.08e-24 0.243 0.308 -0.065 3.22e-21
BMI SBLUP.Inf lassosum.MultiPRS 0.292 0.305 -0.013 5.72e-02 0.287 0.308 -0.021 7.98e-10
BMI pT+clump.MultiPRS lassosum.MultiPRS 0.271 0.305 -0.034 2.07e-07 0.275 0.308 -0.033 1.45e-12
BMI LDpred1.10FCVal lassosum.MultiPRS 0.277 0.305 -0.028 1.79e-05 0.273 0.308 -0.035 7.43e-14
BMI All.MultiPRS lassosum.PseudoVal 0.308 0.211 0.096 1.02e-46 0.308 0.220 0.088 1.27e-30
BMI LDpred1.MultiPRS lassosum.PseudoVal 0.286 0.211 0.074 3.30e-28 0.282 0.220 0.062 1.50e-17
BMI LDpred2.PseudoVal lassosum.PseudoVal 0.237 0.211 0.026 3.92e-43 0.243 0.220 0.023 1.57e-09
BMI DBSLMM.PseudoVal lassosum.PseudoVal 0.283 0.211 0.071 3.32e-107 0.283 0.220 0.063 5.43e-22
BMI LDpred1.Inf lassosum.PseudoVal 0.272 0.211 0.061 1.50e-43 0.264 0.220 0.044 1.01e-06
BMI LDpred2.Inf lassosum.PseudoVal 0.293 0.211 0.081 2.19e-67 0.287 0.220 0.067 1.33e-12
BMI lassosum.MultiPRS lassosum.PseudoVal 0.305 0.211 0.093 2.47e-44 0.308 0.220 0.088 1.11e-30
BMI LDpred1.10FCVal lassosum.PseudoVal 0.277 0.211 0.065 1.19e-103 0.273 0.220 0.053 9.37e-18
BMI lassosum.PseudoVal lassosum.PseudoVal 0.211 0.211 0.000 1.00e+00 0.220 0.220 0.000 1.00e+00
BMI LDpred2.MultiPRS lassosum.PseudoVal 0.305 0.211 0.094 1.87e-44 0.303 0.220 0.083 2.87e-27
BMI pT+clump.10FCVal lassosum.PseudoVal 0.248 0.211 0.037 7.00e-14 0.245 0.220 0.025 1.19e-02
BMI lassosum.10FCVal lassosum.PseudoVal 0.300 0.211 0.089 2.14e-102 0.300 0.220 0.080 1.55e-21
BMI LDpred2.10FCVal lassosum.PseudoVal 0.305 0.211 0.093 9.34e-130 0.302 0.220 0.082 7.58e-26
BMI SBayesR.PseudoVal lassosum.PseudoVal 0.241 0.211 0.030 2.87e-35 0.250 0.220 0.030 8.21e-10
BMI SBLUP.Inf lassosum.PseudoVal 0.292 0.211 0.081 5.69e-67 0.287 0.220 0.067 2.09e-12
BMI pT+clump.MultiPRS lassosum.PseudoVal 0.271 0.211 0.059 3.17e-18 0.275 0.220 0.055 2.02e-12
BMI All.MultiPRS lassosum.10FCVal 0.308 0.300 0.007 2.73e-01 0.308 0.300 0.008 3.12e-04
BMI LDpred1.MultiPRS lassosum.10FCVal 0.286 0.300 -0.015 2.45e-02 0.282 0.300 -0.018 1.45e-05
BMI LDpred1.Inf lassosum.10FCVal 0.272 0.300 -0.028 5.61e-41 0.264 0.300 -0.036 1.72e-17
BMI LDpred2.Inf lassosum.10FCVal 0.293 0.300 -0.008 3.61e-09 0.287 0.300 -0.013 1.83e-06
BMI lassosum.MultiPRS lassosum.10FCVal 0.305 0.300 0.004 5.04e-01 0.308 0.300 0.008 8.54e-06
BMI DBSLMM.PseudoVal lassosum.10FCVal 0.283 0.300 -0.018 1.91e-14 0.283 0.300 -0.017 2.77e-04
BMI lassosum.PseudoVal lassosum.10FCVal 0.211 0.300 -0.089 2.14e-102 0.220 0.300 -0.080 1.55e-21
BMI LDpred2.MultiPRS lassosum.10FCVal 0.305 0.300 0.005 4.67e-01 0.303 0.300 0.003 2.52e-01
BMI pT+clump.10FCVal lassosum.10FCVal 0.248 0.300 -0.052 1.71e-69 0.245 0.300 -0.055 2.11e-20
BMI lassosum.10FCVal lassosum.10FCVal 0.300 0.300 0.000 1.00e+00 0.300 0.300 0.000 1.00e+00
BMI LDpred2.10FCVal lassosum.10FCVal 0.305 0.300 0.004 1.09e-03 0.302 0.300 0.002 4.29e-01
BMI SBayesR.PseudoVal lassosum.10FCVal 0.241 0.300 -0.059 1.17e-57 0.250 0.300 -0.050 1.81e-11
BMI LDpred2.PseudoVal lassosum.10FCVal 0.237 0.300 -0.063 5.24e-63 0.243 0.300 -0.057 8.68e-14
BMI SBLUP.Inf lassosum.10FCVal 0.292 0.300 -0.008 5.76e-10 0.287 0.300 -0.013 2.68e-07
BMI pT+clump.MultiPRS lassosum.10FCVal 0.271 0.300 -0.030 6.31e-06 0.275 0.300 -0.025 9.80e-07
BMI LDpred1.10FCVal lassosum.10FCVal 0.277 0.300 -0.024 1.72e-24 0.273 0.300 -0.027 8.08e-09
BMI DBSLMM.PseudoVal LDpred1.MultiPRS 0.283 0.286 -0.003 6.59e-01 0.283 0.282 0.001 8.64e-01
BMI LDpred2.MultiPRS LDpred1.MultiPRS 0.305 0.286 0.020 2.88e-03 0.303 0.282 0.021 1.26e-08
BMI pT+clump.10FCVal LDpred1.MultiPRS 0.248 0.286 -0.038 1.97e-08 0.245 0.282 -0.037 9.20e-08
BMI lassosum.10FCVal LDpred1.MultiPRS 0.300 0.286 0.015 2.45e-02 0.300 0.282 0.018 1.45e-05
BMI lassosum.PseudoVal LDpred1.MultiPRS 0.211 0.286 -0.074 3.30e-28 0.220 0.282 -0.062 1.50e-17
BMI All.MultiPRS LDpred1.MultiPRS 0.308 0.286 0.022 8.15e-04 0.308 0.282 0.026 6.09e-12
BMI LDpred1.MultiPRS LDpred1.MultiPRS 0.286 0.286 0.000 1.00e+00 0.282 0.282 0.000 1.00e+00
BMI LDpred2.PseudoVal LDpred1.MultiPRS 0.237 0.286 -0.048 7.07e-13 0.243 0.282 -0.039 1.01e-09
BMI SBLUP.Inf LDpred1.MultiPRS 0.292 0.286 0.007 3.09e-01 0.287 0.282 0.004 3.15e-01
BMI LDpred1.Inf LDpred1.MultiPRS 0.272 0.286 -0.013 4.78e-02 0.264 0.282 -0.018 8.04e-11
BMI LDpred2.Inf LDpred1.MultiPRS 0.293 0.286 0.007 2.94e-01 0.287 0.282 0.005 2.53e-01
BMI lassosum.MultiPRS LDpred1.MultiPRS 0.305 0.286 0.019 3.49e-03 0.308 0.282 0.026 6.42e-10
BMI LDpred1.10FCVal LDpred1.MultiPRS 0.277 0.286 -0.009 1.71e-01 0.273 0.282 -0.010 4.92e-05
BMI pT+clump.MultiPRS LDpred1.MultiPRS 0.271 0.286 -0.015 2.34e-02 0.275 0.282 -0.007 2.09e-01
BMI SBayesR.PseudoVal LDpred1.MultiPRS 0.241 0.286 -0.044 4.57e-11 0.250 0.282 -0.032 8.25e-08
BMI LDpred2.10FCVal LDpred1.MultiPRS 0.305 0.286 0.019 3.89e-03 0.302 0.282 0.020 4.91e-08
BMI All.MultiPRS LDpred1.Inf 0.308 0.272 0.035 9.24e-08 0.308 0.264 0.045 3.12e-21
BMI LDpred1.Inf LDpred1.Inf 0.272 0.272 0.000 1.00e+00 0.264 0.264 0.000 1.00e+00
BMI LDpred2.Inf LDpred1.Inf 0.293 0.272 0.020 2.76e-26 0.287 0.264 0.023 1.46e-09
BMI DBSLMM.PseudoVal LDpred1.Inf 0.283 0.272 0.010 1.97e-04 0.283 0.264 0.019 7.19e-04
BMI lassosum.PseudoVal LDpred1.Inf 0.211 0.272 -0.061 1.50e-43 0.220 0.264 -0.044 1.01e-06
BMI LDpred2.MultiPRS LDpred1.Inf 0.305 0.272 0.033 6.60e-07 0.303 0.264 0.039 3.08e-18
BMI pT+clump.10FCVal LDpred1.Inf 0.248 0.272 -0.024 4.18e-12 0.245 0.264 -0.019 8.04e-03
BMI lassosum.10FCVal LDpred1.Inf 0.300 0.272 0.028 5.61e-41 0.300 0.264 0.036 1.72e-17
BMI LDpred2.10FCVal LDpred1.Inf 0.305 0.272 0.032 3.18e-53 0.302 0.264 0.038 5.11e-19
BMI SBayesR.PseudoVal LDpred1.Inf 0.241 0.272 -0.031 1.84e-15 0.250 0.264 -0.014 7.83e-02
BMI LDpred1.MultiPRS LDpred1.Inf 0.286 0.272 0.013 4.78e-02 0.282 0.264 0.018 8.04e-11
BMI LDpred2.PseudoVal LDpred1.Inf 0.237 0.272 -0.035 1.03e-17 0.243 0.264 -0.021 1.22e-02
BMI SBLUP.Inf LDpred1.Inf 0.292 0.272 0.020 2.88e-26 0.287 0.264 0.023 2.97e-09
BMI pT+clump.MultiPRS LDpred1.Inf 0.271 0.272 -0.002 7.75e-01 0.275 0.264 0.011 7.03e-02
BMI lassosum.MultiPRS LDpred1.Inf 0.305 0.272 0.032 9.58e-07 0.308 0.264 0.044 4.32e-19
BMI LDpred1.10FCVal LDpred1.Inf 0.277 0.272 0.004 3.37e-02 0.273 0.264 0.009 2.44e-02
BMI LDpred1.Inf LDpred1.10FCVal 0.272 0.277 -0.004 3.37e-02 0.264 0.273 -0.009 2.44e-02
BMI DBSLMM.PseudoVal LDpred1.10FCVal 0.283 0.277 0.006 3.64e-03 0.283 0.273 0.010 1.70e-02
BMI lassosum.PseudoVal LDpred1.10FCVal 0.211 0.277 -0.065 1.19e-103 0.220 0.273 -0.053 9.37e-18
BMI LDpred2.MultiPRS LDpred1.10FCVal 0.305 0.277 0.029 1.32e-05 0.303 0.273 0.031 4.66e-13
BMI pT+clump.10FCVal LDpred1.10FCVal 0.248 0.277 -0.028 1.51e-14 0.245 0.273 -0.028 2.23e-04
BMI lassosum.10FCVal LDpred1.10FCVal 0.300 0.277 0.024 1.72e-24 0.300 0.273 0.027 8.08e-09
BMI LDpred2.10FCVal LDpred1.10FCVal 0.305 0.277 0.028 2.51e-44 0.302 0.273 0.029 6.42e-13
BMI All.MultiPRS LDpred1.10FCVal 0.308 0.277 0.031 2.30e-06 0.308 0.273 0.036 8.40e-16
BMI LDpred1.MultiPRS LDpred1.10FCVal 0.286 0.277 0.009 1.71e-01 0.282 0.273 0.010 4.92e-05
BMI LDpred2.PseudoVal LDpred1.10FCVal 0.237 0.277 -0.039 1.36e-43 0.243 0.273 -0.030 2.53e-07
BMI SBLUP.Inf LDpred1.10FCVal 0.292 0.277 0.016 2.08e-09 0.287 0.273 0.014 9.42e-03
BMI pT+clump.MultiPRS LDpred1.10FCVal 0.271 0.277 -0.006 3.71e-01 0.275 0.273 0.003 6.63e-01
BMI LDpred2.Inf LDpred1.10FCVal 0.293 0.277 0.016 1.24e-09 0.287 0.273 0.015 6.63e-03
BMI lassosum.MultiPRS LDpred1.10FCVal 0.305 0.277 0.028 1.79e-05 0.308 0.273 0.035 7.43e-14
BMI LDpred1.10FCVal LDpred1.10FCVal 0.277 0.277 0.000 1.00e+00 0.273 0.273 0.000 1.00e+00
BMI SBayesR.PseudoVal LDpred1.10FCVal 0.241 0.277 -0.035 3.92e-35 0.250 0.273 -0.023 7.29e-05
BMI LDpred2.MultiPRS LDpred2.MultiPRS 0.305 0.305 0.000 1.00e+00 0.303 0.303 0.000 1.00e+00
BMI lassosum.PseudoVal LDpred2.MultiPRS 0.211 0.305 -0.094 1.87e-44 0.220 0.303 -0.083 2.87e-27
BMI All.MultiPRS LDpred2.MultiPRS 0.308 0.305 0.002 4.49e-04 0.308 0.303 0.005 1.92e-04
BMI LDpred1.MultiPRS LDpred2.MultiPRS 0.286 0.305 -0.020 2.88e-03 0.282 0.303 -0.021 1.26e-08
BMI DBSLMM.PseudoVal LDpred2.MultiPRS 0.283 0.305 -0.023 6.13e-04 0.283 0.303 -0.020 5.43e-07
BMI LDpred1.Inf LDpred2.MultiPRS 0.272 0.305 -0.033 6.60e-07 0.264 0.303 -0.039 3.08e-18
BMI LDpred2.Inf LDpred2.MultiPRS 0.293 0.305 -0.013 5.32e-02 0.287 0.303 -0.016 1.80e-08
BMI lassosum.MultiPRS LDpred2.MultiPRS 0.305 0.305 0.000 9.55e-01 0.308 0.303 0.004 7.62e-02
BMI LDpred1.10FCVal LDpred2.MultiPRS 0.277 0.305 -0.029 1.32e-05 0.273 0.303 -0.031 4.66e-13
BMI pT+clump.MultiPRS LDpred2.MultiPRS 0.271 0.305 -0.035 1.40e-07 0.275 0.303 -0.028 6.58e-09
BMI SBayesR.PseudoVal LDpred2.MultiPRS 0.241 0.305 -0.064 9.18e-22 0.250 0.303 -0.053 6.15e-17
BMI pT+clump.10FCVal LDpred2.MultiPRS 0.248 0.305 -0.057 6.83e-18 0.245 0.303 -0.058 1.19e-21
BMI lassosum.10FCVal LDpred2.MultiPRS 0.300 0.305 -0.005 4.67e-01 0.300 0.303 -0.003 2.52e-01
BMI LDpred2.10FCVal LDpred2.MultiPRS 0.305 0.305 -0.001 9.28e-01 0.302 0.303 -0.001 2.68e-01
BMI LDpred2.PseudoVal LDpred2.MultiPRS 0.237 0.305 -0.068 2.67e-24 0.243 0.303 -0.060 1.37e-20
BMI SBLUP.Inf LDpred2.MultiPRS 0.292 0.305 -0.013 4.95e-02 0.287 0.303 -0.017 2.75e-08
BMI LDpred2.MultiPRS LDpred2.10FCVal 0.305 0.305 0.001 9.28e-01 0.303 0.302 0.001 2.68e-01
BMI pT+clump.10FCVal LDpred2.10FCVal 0.248 0.305 -0.057 5.53e-78 0.245 0.302 -0.057 5.09e-21
BMI lassosum.PseudoVal LDpred2.10FCVal 0.211 0.305 -0.093 9.34e-130 0.220 0.302 -0.082 7.58e-26
BMI All.MultiPRS LDpred2.10FCVal 0.308 0.305 0.003 6.46e-01 0.308 0.302 0.006 3.17e-04
BMI LDpred1.MultiPRS LDpred2.10FCVal 0.286 0.305 -0.019 3.89e-03 0.282 0.302 -0.020 4.91e-08
BMI LDpred2.PseudoVal LDpred2.10FCVal 0.237 0.305 -0.067 1.17e-91 0.243 0.302 -0.059 2.06e-18
BMI DBSLMM.PseudoVal LDpred2.10FCVal 0.283 0.305 -0.022 1.39e-29 0.283 0.302 -0.019 1.21e-06
BMI LDpred1.Inf LDpred2.10FCVal 0.272 0.305 -0.032 3.18e-53 0.264 0.302 -0.038 5.11e-19
BMI LDpred2.Inf LDpred2.10FCVal 0.293 0.305 -0.012 9.74e-23 0.287 0.302 -0.015 3.20e-09
BMI lassosum.MultiPRS LDpred2.10FCVal 0.305 0.305 0.000 9.74e-01 0.308 0.302 0.006 2.64e-02
BMI LDpred1.10FCVal LDpred2.10FCVal 0.277 0.305 -0.028 2.51e-44 0.273 0.302 -0.029 6.42e-13
BMI pT+clump.MultiPRS LDpred2.10FCVal 0.271 0.305 -0.034 2.56e-07 0.275 0.302 -0.027 3.13e-08
BMI SBayesR.PseudoVal LDpred2.10FCVal 0.241 0.305 -0.063 9.47e-83 0.250 0.302 -0.052 4.22e-15
BMI lassosum.10FCVal LDpred2.10FCVal 0.300 0.305 -0.004 1.09e-03 0.300 0.302 -0.002 4.29e-01
BMI LDpred2.10FCVal LDpred2.10FCVal 0.305 0.305 0.000 1.00e+00 0.302 0.302 0.000 1.00e+00
BMI SBLUP.Inf LDpred2.10FCVal 0.292 0.305 -0.012 1.37e-20 0.287 0.302 -0.016 8.32e-09
BMI LDpred2.MultiPRS LDpred2.PseudoVal 0.305 0.237 0.068 2.67e-24 0.303 0.243 0.060 1.37e-20
BMI lassosum.PseudoVal LDpred2.PseudoVal 0.211 0.237 -0.026 3.92e-43 0.220 0.243 -0.023 1.57e-09
BMI All.MultiPRS LDpred2.PseudoVal 0.308 0.237 0.070 5.88e-26 0.308 0.243 0.065 3.77e-23
BMI LDpred1.MultiPRS LDpred2.PseudoVal 0.286 0.237 0.048 7.07e-13 0.282 0.243 0.039 1.01e-09
BMI DBSLMM.PseudoVal LDpred2.PseudoVal 0.283 0.237 0.045 4.54e-56 0.283 0.243 0.040 5.39e-12
BMI LDpred1.Inf LDpred2.PseudoVal 0.272 0.237 0.035 1.03e-17 0.264 0.243 0.021 1.22e-02
BMI LDpred2.Inf LDpred2.PseudoVal 0.293 0.237 0.055 8.25e-40 0.287 0.243 0.044 1.90e-07
BMI lassosum.MultiPRS LDpred2.PseudoVal 0.305 0.237 0.067 5.08e-24 0.308 0.243 0.065 3.22e-21
BMI LDpred1.10FCVal LDpred2.PseudoVal 0.277 0.237 0.039 1.36e-43 0.273 0.243 0.030 2.53e-07
BMI pT+clump.MultiPRS LDpred2.PseudoVal 0.271 0.237 0.033 9.45e-07 0.275 0.243 0.032 9.74e-06
BMI SBayesR.PseudoVal LDpred2.PseudoVal 0.241 0.237 0.004 6.68e-03 0.250 0.243 0.007 2.04e-02
BMI pT+clump.10FCVal LDpred2.PseudoVal 0.248 0.237 0.011 2.04e-02 0.245 0.243 0.002 8.32e-01
BMI lassosum.10FCVal LDpred2.PseudoVal 0.300 0.237 0.063 5.24e-63 0.300 0.243 0.057 8.68e-14
BMI LDpred2.10FCVal LDpred2.PseudoVal 0.305 0.237 0.067 1.17e-91 0.302 0.243 0.059 2.06e-18
BMI LDpred2.PseudoVal LDpred2.PseudoVal 0.237 0.237 0.000 1.00e+00 0.243 0.243 0.000 1.00e+00
BMI SBLUP.Inf LDpred2.PseudoVal 0.292 0.237 0.055 3.13e-39 0.287 0.243 0.044 3.08e-07
BMI DBSLMM.PseudoVal LDpred2.Inf 0.283 0.293 -0.010 8.13e-05 0.283 0.287 -0.004 4.05e-01
BMI LDpred2.MultiPRS LDpred2.Inf 0.305 0.293 0.013 5.32e-02 0.303 0.287 0.016 1.80e-08
BMI pT+clump.10FCVal LDpred2.Inf 0.248 0.293 -0.045 5.82e-46 0.245 0.287 -0.042 1.29e-11
BMI lassosum.10FCVal LDpred2.Inf 0.300 0.293 0.008 3.61e-09 0.300 0.287 0.013 1.83e-06
BMI lassosum.PseudoVal LDpred2.Inf 0.211 0.293 -0.081 2.19e-67 0.220 0.287 -0.067 1.33e-12
BMI All.MultiPRS LDpred2.Inf 0.308 0.293 0.015 2.14e-02 0.308 0.287 0.021 1.94e-11
BMI LDpred1.MultiPRS LDpred2.Inf 0.286 0.293 -0.007 2.94e-01 0.282 0.287 -0.005 2.53e-01
BMI LDpred2.PseudoVal LDpred2.Inf 0.237 0.293 -0.055 8.25e-40 0.243 0.287 -0.044 1.90e-07
BMI SBLUP.Inf LDpred2.Inf 0.292 0.293 0.000 6.16e-01 0.287 0.287 -0.001 4.62e-01
BMI LDpred1.Inf LDpred2.Inf 0.272 0.293 -0.020 2.76e-26 0.264 0.287 -0.023 1.46e-09
BMI LDpred2.Inf LDpred2.Inf 0.293 0.293 0.000 1.00e+00 0.287 0.287 0.000 1.00e+00
BMI lassosum.MultiPRS LDpred2.Inf 0.305 0.293 0.012 6.14e-02 0.308 0.287 0.021 5.70e-09
BMI LDpred1.10FCVal LDpred2.Inf 0.277 0.293 -0.016 1.24e-09 0.273 0.287 -0.015 6.63e-03
BMI pT+clump.MultiPRS LDpred2.Inf 0.271 0.293 -0.022 9.03e-04 0.275 0.287 -0.012 3.12e-02
BMI SBayesR.PseudoVal LDpred2.Inf 0.241 0.293 -0.051 2.55e-36 0.250 0.287 -0.037 5.73e-06
BMI LDpred2.10FCVal LDpred2.Inf 0.305 0.293 0.012 9.74e-23 0.302 0.287 0.015 3.20e-09
BMI All.MultiPRS pT+clump.MultiPRS 0.308 0.271 0.037 1.76e-08 0.308 0.275 0.033 2.01e-12
BMI LDpred1.MultiPRS pT+clump.MultiPRS 0.286 0.271 0.015 2.34e-02 0.282 0.275 0.007 2.09e-01
BMI LDpred2.PseudoVal pT+clump.MultiPRS 0.237 0.271 -0.033 9.45e-07 0.243 0.275 -0.032 9.74e-06
BMI DBSLMM.PseudoVal pT+clump.MultiPRS 0.283 0.271 0.012 6.85e-02 0.283 0.275 0.008 1.60e-01
BMI LDpred1.Inf pT+clump.MultiPRS 0.272 0.271 0.002 7.75e-01 0.264 0.275 -0.011 7.03e-02
BMI LDpred2.Inf pT+clump.MultiPRS 0.293 0.271 0.022 9.03e-04 0.287 0.275 0.012 3.12e-02
BMI lassosum.MultiPRS pT+clump.MultiPRS 0.305 0.271 0.034 2.07e-07 0.308 0.275 0.033 1.45e-12
BMI LDpred1.10FCVal pT+clump.MultiPRS 0.277 0.271 0.006 3.71e-01 0.273 0.275 -0.003 6.63e-01
BMI lassosum.PseudoVal pT+clump.MultiPRS 0.211 0.271 -0.059 3.17e-18 0.220 0.275 -0.055 2.02e-12
BMI LDpred2.MultiPRS pT+clump.MultiPRS 0.305 0.271 0.035 1.40e-07 0.303 0.275 0.028 6.58e-09
BMI pT+clump.10FCVal pT+clump.MultiPRS 0.248 0.271 -0.023 7.86e-04 0.245 0.275 -0.030 2.91e-14
BMI lassosum.10FCVal pT+clump.MultiPRS 0.300 0.271 0.030 6.31e-06 0.300 0.275 0.025 9.80e-07
BMI LDpred2.10FCVal pT+clump.MultiPRS 0.305 0.271 0.034 2.56e-07 0.302 0.275 0.027 3.13e-08
BMI SBayesR.PseudoVal pT+clump.MultiPRS 0.241 0.271 -0.029 1.61e-05 0.250 0.275 -0.025 4.01e-04
BMI SBLUP.Inf pT+clump.MultiPRS 0.292 0.271 0.022 1.01e-03 0.287 0.275 0.011 3.64e-02
BMI pT+clump.MultiPRS pT+clump.MultiPRS 0.271 0.271 0.000 1.00e+00 0.275 0.275 0.000 1.00e+00
BMI lassosum.PseudoVal pT+clump.10FCVal 0.211 0.248 -0.037 7.00e-14 0.220 0.245 -0.025 1.19e-02
BMI All.MultiPRS pT+clump.10FCVal 0.308 0.248 0.060 2.54e-19 0.308 0.245 0.063 1.79e-26
BMI DBSLMM.PseudoVal pT+clump.10FCVal 0.283 0.248 0.035 1.05e-21 0.283 0.245 0.038 2.53e-07
BMI LDpred1.Inf pT+clump.10FCVal 0.272 0.248 0.024 4.18e-12 0.264 0.245 0.019 8.04e-03
BMI LDpred2.Inf pT+clump.10FCVal 0.293 0.248 0.045 5.82e-46 0.287 0.245 0.042 1.29e-11
BMI lassosum.MultiPRS pT+clump.10FCVal 0.305 0.248 0.057 1.41e-17 0.308 0.245 0.063 2.38e-27
BMI LDpred1.10FCVal pT+clump.10FCVal 0.277 0.248 0.028 1.51e-14 0.273 0.245 0.028 2.23e-04
BMI pT+clump.MultiPRS pT+clump.10FCVal 0.271 0.248 0.023 7.86e-04 0.275 0.245 0.030 2.91e-14
BMI LDpred2.MultiPRS pT+clump.10FCVal 0.305 0.248 0.057 6.83e-18 0.303 0.245 0.058 1.19e-21
BMI pT+clump.10FCVal pT+clump.10FCVal 0.248 0.248 0.000 1.00e+00 0.245 0.245 0.000 1.00e+00
BMI lassosum.10FCVal pT+clump.10FCVal 0.300 0.248 0.052 1.71e-69 0.300 0.245 0.055 2.11e-20
BMI LDpred2.10FCVal pT+clump.10FCVal 0.305 0.248 0.057 5.53e-78 0.302 0.245 0.057 5.09e-21
BMI SBayesR.PseudoVal pT+clump.10FCVal 0.241 0.248 -0.007 1.41e-01 0.250 0.245 0.005 5.80e-01
BMI LDpred1.MultiPRS pT+clump.10FCVal 0.286 0.248 0.038 1.97e-08 0.282 0.245 0.037 9.20e-08
BMI LDpred2.PseudoVal pT+clump.10FCVal 0.237 0.248 -0.011 2.04e-02 0.243 0.245 -0.002 8.32e-01
BMI SBLUP.Inf pT+clump.10FCVal 0.292 0.248 0.044 2.35e-47 0.287 0.245 0.042 1.02e-11
BMI LDpred1.Inf SBayesR.PseudoVal 0.272 0.241 0.031 1.84e-15 0.264 0.250 0.014 7.83e-02
BMI DBSLMM.PseudoVal SBayesR.PseudoVal 0.283 0.241 0.041 2.84e-48 0.283 0.250 0.033 6.28e-09
BMI lassosum.PseudoVal SBayesR.PseudoVal 0.211 0.241 -0.030 2.87e-35 0.220 0.250 -0.030 8.21e-10
BMI LDpred2.MultiPRS SBayesR.PseudoVal 0.305 0.241 0.064 9.18e-22 0.303 0.250 0.053 6.15e-17
BMI pT+clump.10FCVal SBayesR.PseudoVal 0.248 0.241 0.007 1.41e-01 0.245 0.250 -0.005 5.80e-01
BMI lassosum.10FCVal SBayesR.PseudoVal 0.300 0.241 0.059 1.17e-57 0.300 0.250 0.050 1.81e-11
BMI LDpred2.10FCVal SBayesR.PseudoVal 0.305 0.241 0.063 9.47e-83 0.302 0.250 0.052 4.22e-15
BMI All.MultiPRS SBayesR.PseudoVal 0.308 0.241 0.066 2.45e-23 0.308 0.250 0.058 6.71e-20
BMI LDpred1.MultiPRS SBayesR.PseudoVal 0.286 0.241 0.044 4.57e-11 0.282 0.250 0.032 8.25e-08
BMI LDpred2.PseudoVal SBayesR.PseudoVal 0.237 0.241 -0.004 6.68e-03 0.243 0.250 -0.007 2.04e-02
BMI SBLUP.Inf SBayesR.PseudoVal 0.292 0.241 0.051 6.07e-36 0.287 0.250 0.037 8.33e-06
BMI pT+clump.MultiPRS SBayesR.PseudoVal 0.271 0.241 0.029 1.61e-05 0.275 0.250 0.025 4.01e-04
BMI LDpred2.Inf SBayesR.PseudoVal 0.293 0.241 0.051 2.55e-36 0.287 0.250 0.037 5.73e-06
BMI lassosum.MultiPRS SBayesR.PseudoVal 0.305 0.241 0.063 1.90e-21 0.308 0.250 0.058 3.34e-18
BMI LDpred1.10FCVal SBayesR.PseudoVal 0.277 0.241 0.035 3.92e-35 0.273 0.250 0.023 7.29e-05
BMI SBayesR.PseudoVal SBayesR.PseudoVal 0.241 0.241 0.000 1.00e+00 0.250 0.250 0.000 1.00e+00
BMI All.MultiPRS SBLUP.Inf 0.308 0.292 0.015 1.97e-02 0.308 0.287 0.022 7.97e-12
BMI LDpred1.Inf SBLUP.Inf 0.272 0.292 -0.020 2.88e-26 0.264 0.287 -0.023 2.97e-09
BMI LDpred2.Inf SBLUP.Inf 0.293 0.292 0.000 6.16e-01 0.287 0.287 0.001 4.62e-01
BMI DBSLMM.PseudoVal SBLUP.Inf 0.283 0.292 -0.010 1.07e-04 0.283 0.287 -0.004 4.76e-01
BMI lassosum.PseudoVal SBLUP.Inf 0.211 0.292 -0.081 5.69e-67 0.220 0.287 -0.067 2.09e-12
BMI LDpred2.MultiPRS SBLUP.Inf 0.305 0.292 0.013 4.95e-02 0.303 0.287 0.017 2.75e-08
BMI pT+clump.10FCVal SBLUP.Inf 0.248 0.292 -0.044 2.35e-47 0.245 0.287 -0.042 1.02e-11
BMI lassosum.10FCVal SBLUP.Inf 0.300 0.292 0.008 5.76e-10 0.300 0.287 0.013 2.68e-07
BMI LDpred2.10FCVal SBLUP.Inf 0.305 0.292 0.012 1.37e-20 0.302 0.287 0.016 8.32e-09
BMI SBayesR.PseudoVal SBLUP.Inf 0.241 0.292 -0.051 6.07e-36 0.250 0.287 -0.037 8.33e-06
BMI LDpred1.MultiPRS SBLUP.Inf 0.286 0.292 -0.007 3.09e-01 0.282 0.287 -0.004 3.15e-01
BMI LDpred2.PseudoVal SBLUP.Inf 0.237 0.292 -0.055 3.13e-39 0.243 0.287 -0.044 3.08e-07
BMI SBLUP.Inf SBLUP.Inf 0.292 0.292 0.000 1.00e+00 0.287 0.287 0.000 1.00e+00
BMI pT+clump.MultiPRS SBLUP.Inf 0.271 0.292 -0.022 1.01e-03 0.275 0.287 -0.011 3.64e-02
BMI lassosum.MultiPRS SBLUP.Inf 0.305 0.292 0.013 5.72e-02 0.308 0.287 0.021 7.98e-10
BMI LDpred1.10FCVal SBLUP.Inf 0.277 0.292 -0.016 2.08e-09 0.273 0.287 -0.014 9.42e-03
T2D lassosum.PseudoVal All.MultiPRS 0.203 0.243 -0.040 5.82e-09 0.214 0.242 -0.028 1.87e-06
T2D All.MultiPRS All.MultiPRS 0.243 0.243 0.000 1.00e+00 0.242 0.242 0.000 1.00e+00
T2D DBSLMM.PseudoVal All.MultiPRS 0.230 0.243 -0.013 6.00e-02 0.232 0.242 -0.010 7.36e-03
T2D LDpred1.Inf All.MultiPRS 0.185 0.243 -0.057 4.33e-17 0.181 0.242 -0.061 8.14e-19
T2D LDpred2.Inf All.MultiPRS 0.189 0.243 -0.054 2.13e-15 0.185 0.242 -0.057 1.11e-17
T2D lassosum.MultiPRS All.MultiPRS 0.239 0.243 -0.004 5.83e-01 0.243 0.242 0.001 5.94e-01
T2D LDpred1.10FCVal All.MultiPRS 0.224 0.243 -0.019 5.98e-03 0.224 0.242 -0.018 3.29e-05
T2D pT+clump.MultiPRS All.MultiPRS 0.217 0.243 -0.025 1.82e-04 0.221 0.242 -0.021 1.67e-05
T2D LDpred2.MultiPRS All.MultiPRS 0.241 0.243 -0.002 7.81e-01 0.243 0.242 0.001 7.13e-01
T2D pT+clump.10FCVal All.MultiPRS 0.170 0.243 -0.073 2.70e-26 0.174 0.242 -0.068 2.06e-18
T2D lassosum.10FCVal All.MultiPRS 0.213 0.243 -0.030 1.04e-05 0.217 0.242 -0.025 1.69e-06
T2D LDpred2.10FCVal All.MultiPRS 0.237 0.243 -0.006 3.65e-01 0.239 0.242 -0.003 3.19e-01
T2D SBayesR.PseudoVal All.MultiPRS 0.236 0.243 -0.006 3.57e-01 0.236 0.242 -0.006 5.79e-02
T2D LDpred1.MultiPRS All.MultiPRS 0.230 0.243 -0.012 6.90e-02 0.234 0.242 -0.008 3.31e-02
T2D LDpred2.PseudoVal All.MultiPRS 0.227 0.243 -0.016 2.11e-02 0.229 0.242 -0.012 2.79e-03
T2D SBLUP.Inf All.MultiPRS 0.189 0.243 -0.054 1.82e-15 0.183 0.242 -0.059 2.92e-18
T2D LDpred2.MultiPRS DBSLMM.PseudoVal 0.241 0.230 0.011 1.07e-01 0.243 0.232 0.011 2.33e-04
T2D pT+clump.10FCVal DBSLMM.PseudoVal 0.170 0.230 -0.060 6.44e-45 0.174 0.232 -0.057 7.63e-12
T2D lassosum.PseudoVal DBSLMM.PseudoVal 0.203 0.230 -0.027 3.47e-14 0.214 0.232 -0.018 9.11e-03
T2D All.MultiPRS DBSLMM.PseudoVal 0.243 0.230 0.013 6.00e-02 0.242 0.232 0.010 7.36e-03
T2D LDpred1.MultiPRS DBSLMM.PseudoVal 0.230 0.230 0.000 9.57e-01 0.234 0.232 0.002 5.96e-01
T2D LDpred2.PseudoVal DBSLMM.PseudoVal 0.227 0.230 -0.003 2.77e-01 0.229 0.232 -0.002 6.56e-01
T2D DBSLMM.PseudoVal DBSLMM.PseudoVal 0.230 0.230 0.000 1.00e+00 0.232 0.232 0.000 1.00e+00
T2D LDpred1.Inf DBSLMM.PseudoVal 0.185 0.230 -0.045 2.65e-52 0.181 0.232 -0.051 1.44e-18
T2D LDpred2.Inf DBSLMM.PseudoVal 0.189 0.230 -0.041 5.45e-47 0.185 0.232 -0.047 9.65e-17
T2D lassosum.MultiPRS DBSLMM.PseudoVal 0.239 0.230 0.009 1.83e-01 0.243 0.232 0.012 3.99e-04
T2D LDpred1.10FCVal DBSLMM.PseudoVal 0.224 0.230 -0.006 2.48e-03 0.224 0.232 -0.008 3.52e-02
T2D pT+clump.MultiPRS DBSLMM.PseudoVal 0.217 0.230 -0.013 6.40e-02 0.221 0.232 -0.011 2.98e-02
T2D SBayesR.PseudoVal DBSLMM.PseudoVal 0.236 0.230 0.007 1.10e-03 0.236 0.232 0.004 3.01e-01
T2D lassosum.10FCVal DBSLMM.PseudoVal 0.213 0.230 -0.017 4.22e-09 0.217 0.232 -0.015 8.97e-03
T2D LDpred2.10FCVal DBSLMM.PseudoVal 0.237 0.230 0.007 3.02e-04 0.239 0.232 0.007 5.31e-02
T2D SBLUP.Inf DBSLMM.PseudoVal 0.189 0.230 -0.041 3.08e-47 0.183 0.232 -0.048 1.53e-17
T2D All.MultiPRS lassosum.MultiPRS 0.243 0.239 0.004 5.83e-01 0.242 0.243 -0.001 5.94e-01
T2D LDpred1.MultiPRS lassosum.MultiPRS 0.230 0.239 -0.009 2.03e-01 0.234 0.243 -0.009 2.50e-03
T2D LDpred1.Inf lassosum.MultiPRS 0.185 0.239 -0.054 4.10e-15 0.181 0.243 -0.062 9.28e-22
T2D LDpred2.Inf lassosum.MultiPRS 0.189 0.239 -0.050 1.49e-13 0.185 0.243 -0.059 1.37e-19
T2D lassosum.MultiPRS lassosum.MultiPRS 0.239 0.239 0.000 1.00e+00 0.243 0.243 0.000 1.00e+00
T2D DBSLMM.PseudoVal lassosum.MultiPRS 0.230 0.239 -0.009 1.83e-01 0.232 0.243 -0.012 3.99e-04
T2D lassosum.PseudoVal lassosum.MultiPRS 0.203 0.239 -0.036 1.54e-07 0.214 0.243 -0.030 1.82e-08
T2D LDpred2.MultiPRS lassosum.MultiPRS 0.241 0.239 0.002 7.88e-01 0.243 0.243 0.000 8.38e-01
T2D pT+clump.10FCVal lassosum.MultiPRS 0.170 0.239 -0.069 1.07e-23 0.174 0.243 -0.069 4.63e-20
T2D lassosum.10FCVal lassosum.MultiPRS 0.213 0.239 -0.026 1.18e-04 0.217 0.243 -0.027 3.08e-09
T2D LDpred2.10FCVal lassosum.MultiPRS 0.237 0.239 -0.002 7.21e-01 0.239 0.243 -0.005 8.85e-02
T2D SBayesR.PseudoVal lassosum.MultiPRS 0.236 0.239 -0.003 7.10e-01 0.236 0.243 -0.008 8.48e-03
T2D LDpred2.PseudoVal lassosum.MultiPRS 0.227 0.239 -0.012 7.91e-02 0.229 0.243 -0.014 5.03e-04
T2D SBLUP.Inf lassosum.MultiPRS 0.189 0.239 -0.051 1.33e-13 0.183 0.243 -0.060 1.96e-20
T2D pT+clump.MultiPRS lassosum.MultiPRS 0.217 0.239 -0.022 1.40e-03 0.221 0.243 -0.022 7.21e-07
T2D LDpred1.10FCVal lassosum.MultiPRS 0.224 0.239 -0.015 2.80e-02 0.224 0.243 -0.020 2.11e-07
T2D All.MultiPRS lassosum.PseudoVal 0.243 0.203 0.040 5.82e-09 0.242 0.214 0.028 1.87e-06
T2D LDpred1.MultiPRS lassosum.PseudoVal 0.230 0.203 0.027 6.44e-05 0.234 0.214 0.020 3.44e-04
T2D LDpred2.PseudoVal lassosum.PseudoVal 0.227 0.203 0.024 1.02e-27 0.229 0.214 0.016 3.14e-04
T2D DBSLMM.PseudoVal lassosum.PseudoVal 0.230 0.203 0.027 3.47e-14 0.232 0.214 0.018 9.11e-03
T2D LDpred1.Inf lassosum.PseudoVal 0.185 0.203 -0.018 5.81e-04 0.181 0.214 -0.032 1.35e-03
T2D LDpred2.Inf lassosum.PseudoVal 0.189 0.203 -0.014 5.33e-03 0.185 0.214 -0.029 4.83e-03
T2D lassosum.MultiPRS lassosum.PseudoVal 0.239 0.203 0.036 1.54e-07 0.243 0.214 0.030 1.82e-08
T2D LDpred1.10FCVal lassosum.PseudoVal 0.224 0.203 0.021 8.45e-09 0.224 0.214 0.010 1.58e-01
T2D lassosum.PseudoVal lassosum.PseudoVal 0.203 0.203 0.000 1.00e+00 0.214 0.214 0.000 1.00e+00
T2D LDpred2.MultiPRS lassosum.PseudoVal 0.241 0.203 0.038 2.49e-08 0.243 0.214 0.029 2.60e-08
T2D pT+clump.10FCVal lassosum.PseudoVal 0.170 0.203 -0.033 3.11e-26 0.174 0.214 -0.039 3.26e-10
T2D lassosum.10FCVal lassosum.PseudoVal 0.213 0.203 0.010 1.01e-03 0.217 0.214 0.003 6.04e-01
T2D LDpred2.10FCVal lassosum.PseudoVal 0.237 0.203 0.033 3.61e-35 0.239 0.214 0.025 2.79e-06
T2D SBayesR.PseudoVal lassosum.PseudoVal 0.236 0.203 0.033 3.89e-37 0.236 0.214 0.022 2.01e-05
T2D SBLUP.Inf lassosum.PseudoVal 0.189 0.203 -0.015 4.99e-03 0.183 0.214 -0.030 3.28e-03
T2D pT+clump.MultiPRS lassosum.PseudoVal 0.217 0.203 0.014 3.80e-02 0.221 0.214 0.008 2.06e-01
T2D All.MultiPRS lassosum.10FCVal 0.243 0.213 0.030 1.04e-05 0.242 0.217 0.025 1.69e-06
T2D LDpred1.MultiPRS lassosum.10FCVal 0.230 0.213 0.018 9.79e-03 0.234 0.217 0.017 2.43e-05
T2D LDpred1.Inf lassosum.10FCVal 0.185 0.213 -0.027 2.14e-15 0.181 0.217 -0.036 1.48e-07
T2D LDpred2.Inf lassosum.10FCVal 0.189 0.213 -0.024 2.83e-12 0.185 0.217 -0.032 2.44e-06
T2D lassosum.MultiPRS lassosum.10FCVal 0.239 0.213 0.026 1.18e-04 0.243 0.217 0.027 3.08e-09
T2D DBSLMM.PseudoVal lassosum.10FCVal 0.230 0.213 0.017 4.22e-09 0.232 0.217 0.015 8.97e-03
T2D lassosum.PseudoVal lassosum.10FCVal 0.203 0.213 -0.010 1.01e-03 0.214 0.217 -0.003 6.04e-01
T2D LDpred2.MultiPRS lassosum.10FCVal 0.241 0.213 0.028 3.22e-05 0.243 0.217 0.026 2.69e-09
T2D pT+clump.10FCVal lassosum.10FCVal 0.170 0.213 -0.043 5.95e-23 0.174 0.217 -0.042 1.01e-06
T2D lassosum.10FCVal lassosum.10FCVal 0.213 0.213 0.000 1.00e+00 0.217 0.217 0.000 1.00e+00
T2D LDpred2.10FCVal lassosum.10FCVal 0.237 0.213 0.024 6.42e-38 0.239 0.217 0.022 1.74e-09
T2D SBayesR.PseudoVal lassosum.10FCVal 0.236 0.213 0.024 5.06e-26 0.236 0.217 0.019 1.67e-05
T2D LDpred2.PseudoVal lassosum.10FCVal 0.227 0.213 0.014 8.89e-11 0.229 0.217 0.013 3.29e-03
T2D SBLUP.Inf lassosum.10FCVal 0.189 0.213 -0.024 1.78e-12 0.183 0.217 -0.033 8.70e-07
T2D pT+clump.MultiPRS lassosum.10FCVal 0.217 0.213 0.005 5.00e-01 0.221 0.217 0.005 4.70e-01
T2D LDpred1.10FCVal lassosum.10FCVal 0.224 0.213 0.011 6.76e-07 0.224 0.217 0.007 1.14e-01
T2D DBSLMM.PseudoVal LDpred1.MultiPRS 0.230 0.230 0.000 9.57e-01 0.232 0.234 -0.002 5.96e-01
T2D LDpred2.MultiPRS LDpred1.MultiPRS 0.241 0.230 0.010 1.18e-01 0.243 0.234 0.009 7.05e-04
T2D pT+clump.10FCVal LDpred1.MultiPRS 0.170 0.230 -0.060 1.83e-18 0.174 0.234 -0.060 3.51e-13
T2D lassosum.10FCVal LDpred1.MultiPRS 0.213 0.230 -0.018 9.79e-03 0.217 0.234 -0.017 2.43e-05
T2D lassosum.PseudoVal LDpred1.MultiPRS 0.203 0.230 -0.027 6.44e-05 0.214 0.234 -0.020 3.44e-04
T2D All.MultiPRS LDpred1.MultiPRS 0.243 0.230 0.012 6.90e-02 0.242 0.234 0.008 3.31e-02
T2D LDpred1.MultiPRS LDpred1.MultiPRS 0.230 0.230 0.000 1.00e+00 0.234 0.234 0.000 1.00e+00
T2D LDpred2.PseudoVal LDpred1.MultiPRS 0.227 0.230 -0.003 6.29e-01 0.229 0.234 -0.004 2.73e-01
T2D SBLUP.Inf LDpred1.MultiPRS 0.189 0.230 -0.042 1.04e-09 0.183 0.234 -0.050 4.23e-17
T2D LDpred1.Inf LDpred1.MultiPRS 0.185 0.230 -0.045 5.72e-11 0.181 0.234 -0.053 3.39e-20
T2D LDpred2.Inf LDpred1.MultiPRS 0.189 0.230 -0.042 1.15e-09 0.185 0.234 -0.049 2.63e-16
T2D lassosum.MultiPRS LDpred1.MultiPRS 0.239 0.230 0.009 2.03e-01 0.243 0.234 0.009 2.50e-03
T2D LDpred1.10FCVal LDpred1.MultiPRS 0.224 0.230 -0.006 3.57e-01 0.224 0.234 -0.010 1.12e-06
T2D pT+clump.MultiPRS LDpred1.MultiPRS 0.217 0.230 -0.013 5.50e-02 0.221 0.234 -0.013 1.21e-02
T2D SBayesR.PseudoVal LDpred1.MultiPRS 0.236 0.230 0.006 3.67e-01 0.236 0.234 0.002 5.14e-01
T2D LDpred2.10FCVal LDpred1.MultiPRS 0.237 0.230 0.006 3.58e-01 0.239 0.234 0.005 1.90e-02
T2D All.MultiPRS LDpred1.Inf 0.243 0.185 0.057 4.33e-17 0.242 0.181 0.061 8.14e-19
T2D LDpred1.Inf LDpred1.Inf 0.185 0.185 0.000 1.00e+00 0.181 0.181 0.000 1.00e+00
T2D LDpred2.Inf LDpred1.Inf 0.189 0.185 0.003 3.04e-03 0.185 0.181 0.004 8.52e-02
T2D DBSLMM.PseudoVal LDpred1.Inf 0.230 0.185 0.045 2.65e-52 0.232 0.181 0.051 1.44e-18
T2D lassosum.PseudoVal LDpred1.Inf 0.203 0.185 0.018 5.81e-04 0.214 0.181 0.032 1.35e-03
T2D LDpred2.MultiPRS LDpred1.Inf 0.241 0.185 0.055 3.81e-16 0.243 0.181 0.062 1.89e-22
T2D pT+clump.10FCVal LDpred1.Inf 0.170 0.185 -0.015 6.96e-03 0.174 0.181 -0.007 5.51e-01
T2D lassosum.10FCVal LDpred1.Inf 0.213 0.185 0.027 2.14e-15 0.217 0.181 0.036 1.48e-07
T2D LDpred2.10FCVal LDpred1.Inf 0.237 0.185 0.051 5.22e-64 0.239 0.181 0.058 2.30e-22
T2D SBayesR.PseudoVal LDpred1.Inf 0.236 0.185 0.051 2.02e-51 0.236 0.181 0.055 1.24e-16
T2D LDpred1.MultiPRS LDpred1.Inf 0.230 0.185 0.045 5.72e-11 0.234 0.181 0.053 3.39e-20
T2D LDpred2.PseudoVal LDpred1.Inf 0.227 0.185 0.042 3.17e-25 0.229 0.181 0.048 8.23e-10
T2D SBLUP.Inf LDpred1.Inf 0.189 0.185 0.003 2.68e-03 0.183 0.181 0.002 2.39e-01
T2D pT+clump.MultiPRS LDpred1.Inf 0.217 0.185 0.032 3.23e-06 0.221 0.181 0.040 7.86e-07
T2D lassosum.MultiPRS LDpred1.Inf 0.239 0.185 0.054 4.10e-15 0.243 0.181 0.062 9.28e-22
T2D LDpred1.10FCVal LDpred1.Inf 0.224 0.185 0.039 4.57e-90 0.224 0.181 0.043 5.83e-30
T2D LDpred1.Inf LDpred1.10FCVal 0.185 0.224 -0.039 4.57e-90 0.181 0.224 -0.043 5.83e-30
T2D DBSLMM.PseudoVal LDpred1.10FCVal 0.230 0.224 0.006 2.48e-03 0.232 0.224 0.008 3.52e-02
T2D lassosum.PseudoVal LDpred1.10FCVal 0.203 0.224 -0.021 8.45e-09 0.214 0.224 -0.010 1.58e-01
T2D LDpred2.MultiPRS LDpred1.10FCVal 0.241 0.224 0.017 1.30e-02 0.243 0.224 0.019 2.14e-08
T2D pT+clump.10FCVal LDpred1.10FCVal 0.170 0.224 -0.054 1.56e-31 0.174 0.224 -0.049 7.56e-08
T2D lassosum.10FCVal LDpred1.10FCVal 0.213 0.224 -0.011 6.76e-07 0.217 0.224 -0.007 1.14e-01
T2D LDpred2.10FCVal LDpred1.10FCVal 0.237 0.224 0.013 3.78e-18 0.239 0.224 0.015 1.01e-07
T2D All.MultiPRS LDpred1.10FCVal 0.243 0.224 0.019 5.98e-03 0.242 0.224 0.018 3.29e-05
T2D LDpred1.MultiPRS LDpred1.10FCVal 0.230 0.224 0.006 3.57e-01 0.234 0.224 0.010 1.12e-06
T2D LDpred2.PseudoVal LDpred1.10FCVal 0.227 0.224 0.003 2.53e-01 0.229 0.224 0.006 2.67e-01
T2D SBLUP.Inf LDpred1.10FCVal 0.189 0.224 -0.036 1.08e-60 0.183 0.224 -0.040 8.61e-22
T2D pT+clump.MultiPRS LDpred1.10FCVal 0.217 0.224 -0.007 3.22e-01 0.221 0.224 -0.003 6.62e-01
T2D LDpred2.Inf LDpred1.10FCVal 0.189 0.224 -0.035 1.00e-59 0.185 0.224 -0.039 2.16e-20
T2D lassosum.MultiPRS LDpred1.10FCVal 0.239 0.224 0.015 2.80e-02 0.243 0.224 0.020 2.11e-07
T2D LDpred1.10FCVal LDpred1.10FCVal 0.224 0.224 0.000 1.00e+00 0.224 0.224 0.000 1.00e+00
T2D SBayesR.PseudoVal LDpred1.10FCVal 0.236 0.224 0.012 1.42e-10 0.236 0.224 0.012 1.39e-03
T2D LDpred2.MultiPRS LDpred2.MultiPRS 0.241 0.241 0.000 1.00e+00 0.243 0.243 0.000 1.00e+00
T2D lassosum.PseudoVal LDpred2.MultiPRS 0.203 0.241 -0.038 2.49e-08 0.214 0.243 -0.029 2.60e-08
T2D All.MultiPRS LDpred2.MultiPRS 0.243 0.241 0.002 7.81e-01 0.242 0.243 -0.001 7.13e-01
T2D LDpred1.MultiPRS LDpred2.MultiPRS 0.230 0.241 -0.010 1.18e-01 0.234 0.243 -0.009 7.05e-04
T2D DBSLMM.PseudoVal LDpred2.MultiPRS 0.230 0.241 -0.011 1.07e-01 0.232 0.243 -0.011 2.33e-04
T2D LDpred1.Inf LDpred2.MultiPRS 0.185 0.241 -0.055 3.81e-16 0.181 0.243 -0.062 1.89e-22
T2D LDpred2.Inf LDpred2.MultiPRS 0.189 0.241 -0.052 1.51e-14 0.185 0.243 -0.058 1.41e-20
T2D lassosum.MultiPRS LDpred2.MultiPRS 0.239 0.241 -0.002 7.88e-01 0.243 0.243 0.000 8.38e-01
T2D LDpred1.10FCVal LDpred2.MultiPRS 0.224 0.241 -0.017 1.30e-02 0.224 0.243 -0.019 2.14e-08
T2D pT+clump.MultiPRS LDpred2.MultiPRS 0.217 0.241 -0.024 5.53e-04 0.221 0.243 -0.022 8.74e-07
T2D SBayesR.PseudoVal LDpred2.MultiPRS 0.236 0.241 -0.004 5.17e-01 0.236 0.243 -0.007 8.31e-04
T2D pT+clump.10FCVal LDpred2.MultiPRS 0.170 0.241 -0.071 3.09e-25 0.174 0.243 -0.069 1.09e-20
T2D lassosum.10FCVal LDpred2.MultiPRS 0.213 0.241 -0.028 3.22e-05 0.217 0.243 -0.026 2.69e-09
T2D LDpred2.10FCVal LDpred2.MultiPRS 0.237 0.241 -0.004 5.27e-01 0.239 0.243 -0.004 1.19e-02
T2D LDpred2.PseudoVal LDpred2.MultiPRS 0.227 0.241 -0.014 4.08e-02 0.229 0.243 -0.013 1.49e-05
T2D SBLUP.Inf LDpred2.MultiPRS 0.189 0.241 -0.052 1.35e-14 0.183 0.243 -0.059 4.66e-21
T2D LDpred2.MultiPRS LDpred2.10FCVal 0.241 0.237 0.004 5.27e-01 0.243 0.239 0.004 1.19e-02
T2D pT+clump.10FCVal LDpred2.10FCVal 0.170 0.237 -0.066 5.34e-65 0.174 0.239 -0.064 1.30e-16
T2D lassosum.PseudoVal LDpred2.10FCVal 0.203 0.237 -0.033 3.61e-35 0.214 0.239 -0.025 2.79e-06
T2D All.MultiPRS LDpred2.10FCVal 0.243 0.237 0.006 3.65e-01 0.242 0.239 0.003 3.19e-01
T2D LDpred1.MultiPRS LDpred2.10FCVal 0.230 0.237 -0.006 3.58e-01 0.234 0.239 -0.005 1.90e-02
T2D LDpred2.PseudoVal LDpred2.10FCVal 0.227 0.237 -0.010 3.84e-10 0.229 0.239 -0.009 2.01e-03
T2D DBSLMM.PseudoVal LDpred2.10FCVal 0.230 0.237 -0.007 3.02e-04 0.232 0.239 -0.007 5.31e-02
T2D LDpred1.Inf LDpred2.10FCVal 0.185 0.237 -0.051 5.22e-64 0.181 0.239 -0.058 2.30e-22
T2D LDpred2.Inf LDpred2.10FCVal 0.189 0.237 -0.048 7.18e-58 0.185 0.239 -0.054 2.15e-20
T2D lassosum.MultiPRS LDpred2.10FCVal 0.239 0.237 0.002 7.21e-01 0.243 0.239 0.005 8.85e-02
T2D LDpred1.10FCVal LDpred2.10FCVal 0.224 0.237 -0.013 3.78e-18 0.224 0.239 -0.015 1.01e-07
T2D pT+clump.MultiPRS LDpred2.10FCVal 0.217 0.237 -0.019 4.68e-03 0.221 0.239 -0.018 2.73e-04
T2D SBayesR.PseudoVal LDpred2.10FCVal 0.236 0.237 0.000 9.30e-01 0.236 0.239 -0.003 2.01e-01
T2D lassosum.10FCVal LDpred2.10FCVal 0.213 0.237 -0.024 6.42e-38 0.217 0.239 -0.022 1.74e-09
T2D LDpred2.10FCVal LDpred2.10FCVal 0.237 0.237 0.000 1.00e+00 0.239 0.239 0.000 1.00e+00
T2D SBLUP.Inf LDpred2.10FCVal 0.189 0.237 -0.048 2.29e-57 0.183 0.239 -0.055 5.49e-21
T2D LDpred2.MultiPRS LDpred2.PseudoVal 0.241 0.227 0.014 4.08e-02 0.243 0.229 0.013 1.49e-05
T2D lassosum.PseudoVal LDpred2.PseudoVal 0.203 0.227 -0.024 1.02e-27 0.214 0.229 -0.016 3.14e-04
T2D All.MultiPRS LDpred2.PseudoVal 0.243 0.227 0.016 2.11e-02 0.242 0.229 0.012 2.79e-03
T2D LDpred1.MultiPRS LDpred2.PseudoVal 0.230 0.227 0.003 6.29e-01 0.234 0.229 0.004 2.73e-01
T2D DBSLMM.PseudoVal LDpred2.PseudoVal 0.230 0.227 0.003 2.77e-01 0.232 0.229 0.002 6.56e-01
T2D LDpred1.Inf LDpred2.PseudoVal 0.185 0.227 -0.042 3.17e-25 0.181 0.229 -0.048 8.23e-10
T2D LDpred2.Inf LDpred2.PseudoVal 0.189 0.227 -0.038 8.77e-22 0.185 0.229 -0.045 1.20e-08
T2D lassosum.MultiPRS LDpred2.PseudoVal 0.239 0.227 0.012 7.91e-02 0.243 0.229 0.014 5.03e-04
T2D LDpred1.10FCVal LDpred2.PseudoVal 0.224 0.227 -0.003 2.53e-01 0.224 0.229 -0.006 2.67e-01
T2D pT+clump.MultiPRS LDpred2.PseudoVal 0.217 0.227 -0.010 1.54e-01 0.221 0.229 -0.008 1.16e-01
T2D SBayesR.PseudoVal LDpred2.PseudoVal 0.236 0.227 0.009 1.42e-11 0.236 0.229 0.006 2.19e-02
T2D pT+clump.10FCVal LDpred2.PseudoVal 0.170 0.227 -0.057 5.05e-67 0.174 0.229 -0.055 5.90e-17
T2D lassosum.10FCVal LDpred2.PseudoVal 0.213 0.227 -0.014 8.89e-11 0.217 0.229 -0.013 3.29e-03
T2D LDpred2.10FCVal LDpred2.PseudoVal 0.237 0.227 0.010 3.84e-10 0.239 0.229 0.009 2.01e-03
T2D LDpred2.PseudoVal LDpred2.PseudoVal 0.227 0.227 0.000 1.00e+00 0.229 0.229 0.000 1.00e+00
T2D SBLUP.Inf LDpred2.PseudoVal 0.189 0.227 -0.039 9.37e-22 0.183 0.229 -0.046 5.36e-09
T2D DBSLMM.PseudoVal LDpred2.Inf 0.230 0.189 0.041 5.45e-47 0.232 0.185 0.047 9.65e-17
T2D LDpred2.MultiPRS LDpred2.Inf 0.241 0.189 0.052 1.51e-14 0.243 0.185 0.058 1.41e-20
T2D pT+clump.10FCVal LDpred2.Inf 0.170 0.189 -0.019 1.20e-03 0.174 0.185 -0.010 3.63e-01
T2D lassosum.10FCVal LDpred2.Inf 0.213 0.189 0.024 2.83e-12 0.217 0.185 0.032 2.44e-06
T2D lassosum.PseudoVal LDpred2.Inf 0.203 0.189 0.014 5.33e-03 0.214 0.185 0.029 4.83e-03
T2D All.MultiPRS LDpred2.Inf 0.243 0.189 0.054 2.13e-15 0.242 0.185 0.057 1.11e-17
T2D LDpred1.MultiPRS LDpred2.Inf 0.230 0.189 0.042 1.15e-09 0.234 0.185 0.049 2.63e-16
T2D LDpred2.PseudoVal LDpred2.Inf 0.227 0.189 0.038 8.77e-22 0.229 0.185 0.045 1.20e-08
T2D SBLUP.Inf LDpred2.Inf 0.189 0.189 0.000 7.93e-01 0.183 0.185 -0.001 1.28e-01
T2D LDpred1.Inf LDpred2.Inf 0.185 0.189 -0.003 3.04e-03 0.181 0.185 -0.004 8.52e-02
T2D LDpred2.Inf LDpred2.Inf 0.189 0.189 0.000 1.00e+00 0.185 0.185 0.000 1.00e+00
T2D lassosum.MultiPRS LDpred2.Inf 0.239 0.189 0.050 1.49e-13 0.243 0.185 0.059 1.37e-19
T2D LDpred1.10FCVal LDpred2.Inf 0.224 0.189 0.035 1.00e-59 0.224 0.185 0.039 2.16e-20
T2D pT+clump.MultiPRS LDpred2.Inf 0.217 0.189 0.029 2.79e-05 0.221 0.185 0.037 7.10e-06
T2D SBayesR.PseudoVal LDpred2.Inf 0.236 0.189 0.048 2.26e-44 0.236 0.185 0.051 1.92e-14
T2D LDpred2.10FCVal LDpred2.Inf 0.237 0.189 0.048 7.18e-58 0.239 0.185 0.054 2.15e-20
T2D All.MultiPRS pT+clump.MultiPRS 0.243 0.217 0.025 1.82e-04 0.242 0.221 0.021 1.67e-05
T2D LDpred1.MultiPRS pT+clump.MultiPRS 0.230 0.217 0.013 5.50e-02 0.234 0.221 0.013 1.21e-02
T2D LDpred2.PseudoVal pT+clump.MultiPRS 0.227 0.217 0.010 1.54e-01 0.229 0.221 0.008 1.16e-01
T2D DBSLMM.PseudoVal pT+clump.MultiPRS 0.230 0.217 0.013 6.40e-02 0.232 0.221 0.011 2.98e-02
T2D LDpred1.Inf pT+clump.MultiPRS 0.185 0.217 -0.032 3.23e-06 0.181 0.221 -0.040 7.86e-07
T2D LDpred2.Inf pT+clump.MultiPRS 0.189 0.217 -0.029 2.79e-05 0.185 0.221 -0.037 7.10e-06
T2D lassosum.MultiPRS pT+clump.MultiPRS 0.239 0.217 0.022 1.40e-03 0.243 0.221 0.022 7.21e-07
T2D LDpred1.10FCVal pT+clump.MultiPRS 0.224 0.217 0.007 3.22e-01 0.224 0.221 0.003 6.62e-01
T2D lassosum.PseudoVal pT+clump.MultiPRS 0.203 0.217 -0.014 3.80e-02 0.214 0.221 -0.008 2.06e-01
T2D LDpred2.MultiPRS pT+clump.MultiPRS 0.241 0.217 0.024 5.53e-04 0.243 0.221 0.022 8.74e-07
T2D pT+clump.10FCVal pT+clump.MultiPRS 0.170 0.217 -0.047 8.48e-12 0.174 0.221 -0.047 4.13e-13
T2D lassosum.10FCVal pT+clump.MultiPRS 0.213 0.217 -0.005 5.00e-01 0.217 0.221 -0.005 4.70e-01
T2D LDpred2.10FCVal pT+clump.MultiPRS 0.237 0.217 0.019 4.68e-03 0.239 0.221 0.018 2.73e-04
T2D SBayesR.PseudoVal pT+clump.MultiPRS 0.236 0.217 0.019 4.96e-03 0.236 0.221 0.015 1.84e-03
T2D SBLUP.Inf pT+clump.MultiPRS 0.189 0.217 -0.029 2.60e-05 0.183 0.221 -0.038 3.43e-06
T2D pT+clump.MultiPRS pT+clump.MultiPRS 0.217 0.217 0.000 1.00e+00 0.221 0.221 0.000 1.00e+00
T2D lassosum.PseudoVal pT+clump.10FCVal 0.203 0.170 0.033 3.11e-26 0.214 0.174 0.039 3.26e-10
T2D All.MultiPRS pT+clump.10FCVal 0.243 0.170 0.073 2.70e-26 0.242 0.174 0.068 2.06e-18
T2D DBSLMM.PseudoVal pT+clump.10FCVal 0.230 0.170 0.060 6.44e-45 0.232 0.174 0.057 7.63e-12
T2D LDpred1.Inf pT+clump.10FCVal 0.185 0.170 0.015 6.96e-03 0.181 0.174 0.007 5.51e-01
T2D LDpred2.Inf pT+clump.10FCVal 0.189 0.170 0.019 1.20e-03 0.185 0.174 0.010 3.63e-01
T2D lassosum.MultiPRS pT+clump.10FCVal 0.239 0.170 0.069 1.07e-23 0.243 0.174 0.069 4.63e-20
T2D LDpred1.10FCVal pT+clump.10FCVal 0.224 0.170 0.054 1.56e-31 0.224 0.174 0.049 7.56e-08
T2D pT+clump.MultiPRS pT+clump.10FCVal 0.217 0.170 0.047 8.48e-12 0.221 0.174 0.047 4.13e-13
T2D LDpred2.MultiPRS pT+clump.10FCVal 0.241 0.170 0.071 3.09e-25 0.243 0.174 0.069 1.09e-20
T2D pT+clump.10FCVal pT+clump.10FCVal 0.170 0.170 0.000 1.00e+00 0.174 0.174 0.000 1.00e+00
T2D lassosum.10FCVal pT+clump.10FCVal 0.213 0.170 0.043 5.95e-23 0.217 0.174 0.042 1.01e-06
T2D LDpred2.10FCVal pT+clump.10FCVal 0.237 0.170 0.066 5.34e-65 0.239 0.174 0.064 1.30e-16
T2D SBayesR.PseudoVal pT+clump.10FCVal 0.236 0.170 0.066 2.78e-74 0.236 0.174 0.061 2.70e-17
T2D LDpred1.MultiPRS pT+clump.10FCVal 0.230 0.170 0.060 1.83e-18 0.234 0.174 0.060 3.51e-13
T2D LDpred2.PseudoVal pT+clump.10FCVal 0.227 0.170 0.057 5.05e-67 0.229 0.174 0.055 5.90e-17
T2D SBLUP.Inf pT+clump.10FCVal 0.189 0.170 0.018 1.27e-03 0.183 0.174 0.009 4.24e-01
T2D LDpred1.Inf SBayesR.PseudoVal 0.185 0.236 -0.051 2.02e-51 0.181 0.236 -0.055 1.24e-16
T2D DBSLMM.PseudoVal SBayesR.PseudoVal 0.230 0.236 -0.007 1.10e-03 0.232 0.236 -0.004 3.01e-01
T2D lassosum.PseudoVal SBayesR.PseudoVal 0.203 0.236 -0.033 3.89e-37 0.214 0.236 -0.022 2.01e-05
T2D LDpred2.MultiPRS SBayesR.PseudoVal 0.241 0.236 0.004 5.17e-01 0.243 0.236 0.007 8.31e-04
T2D pT+clump.10FCVal SBayesR.PseudoVal 0.170 0.236 -0.066 2.78e-74 0.174 0.236 -0.061 2.70e-17
T2D lassosum.10FCVal SBayesR.PseudoVal 0.213 0.236 -0.024 5.06e-26 0.217 0.236 -0.019 1.67e-05
T2D LDpred2.10FCVal SBayesR.PseudoVal 0.237 0.236 0.000 9.30e-01 0.239 0.236 0.003 2.01e-01
T2D All.MultiPRS SBayesR.PseudoVal 0.243 0.236 0.006 3.57e-01 0.242 0.236 0.006 5.79e-02
T2D LDpred1.MultiPRS SBayesR.PseudoVal 0.230 0.236 -0.006 3.67e-01 0.234 0.236 -0.002 5.14e-01
T2D LDpred2.PseudoVal SBayesR.PseudoVal 0.227 0.236 -0.009 1.42e-11 0.229 0.236 -0.006 2.19e-02
T2D SBLUP.Inf SBayesR.PseudoVal 0.189 0.236 -0.048 2.02e-44 0.183 0.236 -0.052 5.16e-15
T2D pT+clump.MultiPRS SBayesR.PseudoVal 0.217 0.236 -0.019 4.96e-03 0.221 0.236 -0.015 1.84e-03
T2D LDpred2.Inf SBayesR.PseudoVal 0.189 0.236 -0.048 2.26e-44 0.185 0.236 -0.051 1.92e-14
T2D lassosum.MultiPRS SBayesR.PseudoVal 0.239 0.236 0.003 7.10e-01 0.243 0.236 0.008 8.48e-03
T2D LDpred1.10FCVal SBayesR.PseudoVal 0.224 0.236 -0.012 1.42e-10 0.224 0.236 -0.012 1.39e-03
T2D SBayesR.PseudoVal SBayesR.PseudoVal 0.236 0.236 0.000 1.00e+00 0.236 0.236 0.000 1.00e+00
T2D All.MultiPRS SBLUP.Inf 0.243 0.189 0.054 1.82e-15 0.242 0.183 0.059 2.92e-18
T2D LDpred1.Inf SBLUP.Inf 0.185 0.189 -0.003 2.68e-03 0.181 0.183 -0.002 2.39e-01
T2D LDpred2.Inf SBLUP.Inf 0.189 0.189 0.000 7.93e-01 0.185 0.183 0.001 1.28e-01
T2D DBSLMM.PseudoVal SBLUP.Inf 0.230 0.189 0.041 3.08e-47 0.232 0.183 0.048 1.53e-17
T2D lassosum.PseudoVal SBLUP.Inf 0.203 0.189 0.015 4.99e-03 0.214 0.183 0.030 3.28e-03
T2D LDpred2.MultiPRS SBLUP.Inf 0.241 0.189 0.052 1.35e-14 0.243 0.183 0.059 4.66e-21
T2D pT+clump.10FCVal SBLUP.Inf 0.170 0.189 -0.018 1.27e-03 0.174 0.183 -0.009 4.24e-01
T2D lassosum.10FCVal SBLUP.Inf 0.213 0.189 0.024 1.78e-12 0.217 0.183 0.033 8.70e-07
T2D LDpred2.10FCVal SBLUP.Inf 0.237 0.189 0.048 2.29e-57 0.239 0.183 0.055 5.49e-21
T2D SBayesR.PseudoVal SBLUP.Inf 0.236 0.189 0.048 2.02e-44 0.236 0.183 0.052 5.16e-15
T2D LDpred1.MultiPRS SBLUP.Inf 0.230 0.189 0.042 1.04e-09 0.234 0.183 0.050 4.23e-17
T2D LDpred2.PseudoVal SBLUP.Inf 0.227 0.189 0.039 9.37e-22 0.229 0.183 0.046 5.36e-09
T2D SBLUP.Inf SBLUP.Inf 0.189 0.189 0.000 1.00e+00 0.183 0.183 0.000 1.00e+00
T2D pT+clump.MultiPRS SBLUP.Inf 0.217 0.189 0.029 2.60e-05 0.221 0.183 0.038 3.43e-06
T2D lassosum.MultiPRS SBLUP.Inf 0.239 0.189 0.051 1.33e-13 0.243 0.183 0.060 1.96e-20
T2D LDpred1.10FCVal SBLUP.Inf 0.224 0.189 0.036 1.08e-60 0.224 0.183 0.040 8.61e-22
CAD lassosum.PseudoVal All.MultiPRS 0.162 0.190 -0.028 1.84e-05 0.160 0.189 -0.030 3.91e-08
CAD All.MultiPRS All.MultiPRS 0.190 0.190 0.000 1.00e+00 0.189 0.189 0.000 1.00e+00
CAD DBSLMM.PseudoVal All.MultiPRS 0.169 0.190 -0.021 1.31e-03 0.163 0.189 -0.027 5.79e-08
CAD LDpred1.Inf All.MultiPRS 0.147 0.190 -0.043 1.02e-10 0.148 0.189 -0.042 6.41e-10
CAD LDpred2.Inf All.MultiPRS 0.161 0.190 -0.029 7.72e-06 0.157 0.189 -0.033 8.81e-09
CAD lassosum.MultiPRS All.MultiPRS 0.187 0.190 -0.004 5.90e-01 0.182 0.189 -0.008 7.51e-04
CAD LDpred1.10FCVal All.MultiPRS 0.172 0.190 -0.019 4.53e-03 0.171 0.189 -0.018 5.44e-05
CAD pT+clump.MultiPRS All.MultiPRS 0.170 0.190 -0.020 3.60e-03 0.166 0.189 -0.024 4.50e-07
CAD LDpred2.MultiPRS All.MultiPRS 0.190 0.190 -0.001 9.30e-01 0.188 0.189 -0.001 5.05e-01
CAD pT+clump.10FCVal All.MultiPRS 0.139 0.190 -0.052 8.34e-15 0.126 0.189 -0.063 7.79e-18
CAD lassosum.10FCVal All.MultiPRS 0.174 0.190 -0.016 1.54e-02 0.171 0.189 -0.019 8.48e-06
CAD LDpred2.10FCVal All.MultiPRS 0.187 0.190 -0.003 6.02e-01 0.184 0.189 -0.005 2.23e-02
CAD SBayesR.PseudoVal All.MultiPRS 0.164 0.190 -0.026 5.85e-05 0.170 0.189 -0.019 2.94e-04
CAD LDpred1.MultiPRS All.MultiPRS 0.173 0.190 -0.018 1.02e-02 0.173 0.189 -0.017 1.44e-04
CAD LDpred2.PseudoVal All.MultiPRS 0.052 0.190 -0.138 1.89e-90 0.060 0.189 -0.130 9.45e-28
CAD SBLUP.Inf All.MultiPRS 0.161 0.190 -0.030 6.73e-06 0.156 0.189 -0.033 3.43e-09
CAD LDpred2.MultiPRS DBSLMM.PseudoVal 0.190 0.169 0.020 3.03e-03 0.188 0.163 0.025 8.10e-07
CAD pT+clump.10FCVal DBSLMM.PseudoVal 0.139 0.169 -0.031 2.73e-11 0.126 0.163 -0.036 6.89e-05
CAD lassosum.PseudoVal DBSLMM.PseudoVal 0.162 0.169 -0.007 3.10e-02 0.160 0.163 -0.003 6.13e-01
CAD All.MultiPRS DBSLMM.PseudoVal 0.190 0.169 0.021 1.31e-03 0.189 0.163 0.027 5.79e-08
CAD LDpred1.MultiPRS DBSLMM.PseudoVal 0.173 0.169 0.003 6.28e-01 0.173 0.163 0.010 7.89e-02
CAD LDpred2.PseudoVal DBSLMM.PseudoVal 0.052 0.169 -0.117 1.05e-81 0.060 0.163 -0.103 6.58e-17
CAD DBSLMM.PseudoVal DBSLMM.PseudoVal 0.169 0.169 0.000 1.00e+00 0.163 0.163 0.000 1.00e+00
CAD LDpred1.Inf DBSLMM.PseudoVal 0.147 0.169 -0.022 2.50e-07 0.148 0.163 -0.015 7.54e-02
CAD LDpred2.Inf DBSLMM.PseudoVal 0.161 0.169 -0.008 3.55e-02 0.157 0.163 -0.006 4.59e-01
CAD lassosum.MultiPRS DBSLMM.PseudoVal 0.187 0.169 0.017 1.20e-02 0.182 0.163 0.019 8.49e-04
CAD LDpred1.10FCVal DBSLMM.PseudoVal 0.172 0.169 0.002 3.80e-01 0.171 0.163 0.008 1.33e-01
CAD pT+clump.MultiPRS DBSLMM.PseudoVal 0.170 0.169 0.001 8.92e-01 0.166 0.163 0.003 6.15e-01
CAD SBayesR.PseudoVal DBSLMM.PseudoVal 0.164 0.169 -0.005 3.49e-02 0.170 0.163 0.007 1.66e-01
CAD lassosum.10FCVal DBSLMM.PseudoVal 0.174 0.169 0.005 1.51e-01 0.171 0.163 0.008 2.91e-01
CAD LDpred2.10FCVal DBSLMM.PseudoVal 0.187 0.169 0.018 1.17e-11 0.184 0.163 0.021 5.78e-05
CAD SBLUP.Inf DBSLMM.PseudoVal 0.161 0.169 -0.009 2.97e-02 0.156 0.163 -0.007 3.88e-01
CAD All.MultiPRS lassosum.MultiPRS 0.190 0.187 0.004 5.90e-01 0.189 0.182 0.008 7.51e-04
CAD LDpred1.MultiPRS lassosum.MultiPRS 0.173 0.187 -0.014 4.12e-02 0.173 0.182 -0.009 5.62e-02
CAD LDpred1.Inf lassosum.MultiPRS 0.147 0.187 -0.039 1.45e-08 0.148 0.182 -0.034 5.03e-07
CAD LDpred2.Inf lassosum.MultiPRS 0.161 0.187 -0.026 1.91e-04 0.157 0.182 -0.025 1.16e-05
CAD lassosum.MultiPRS lassosum.MultiPRS 0.187 0.187 0.000 1.00e+00 0.182 0.182 0.000 1.00e+00
CAD DBSLMM.PseudoVal lassosum.MultiPRS 0.169 0.187 -0.017 1.20e-02 0.163 0.182 -0.019 8.49e-04
CAD lassosum.PseudoVal lassosum.MultiPRS 0.162 0.187 -0.024 4.12e-04 0.160 0.182 -0.022 1.35e-05
CAD LDpred2.MultiPRS lassosum.MultiPRS 0.190 0.187 0.003 6.53e-01 0.188 0.182 0.007 1.93e-02
CAD pT+clump.10FCVal lassosum.MultiPRS 0.139 0.187 -0.048 5.13e-12 0.126 0.182 -0.055 1.76e-13
CAD lassosum.10FCVal lassosum.MultiPRS 0.174 0.187 -0.012 7.79e-02 0.171 0.182 -0.011 1.16e-03
CAD LDpred2.10FCVal lassosum.MultiPRS 0.187 0.187 0.000 9.65e-01 0.184 0.182 0.002 4.28e-01
CAD SBayesR.PseudoVal lassosum.MultiPRS 0.164 0.187 -0.023 1.02e-03 0.170 0.182 -0.012 4.36e-02
CAD LDpred2.PseudoVal lassosum.MultiPRS 0.052 0.187 -0.135 2.19e-82 0.060 0.182 -0.122 4.64e-23
CAD SBLUP.Inf lassosum.MultiPRS 0.161 0.187 -0.026 1.70e-04 0.156 0.182 -0.026 4.54e-06
CAD pT+clump.MultiPRS lassosum.MultiPRS 0.170 0.187 -0.016 1.74e-02 0.166 0.182 -0.016 1.48e-03
CAD LDpred1.10FCVal lassosum.MultiPRS 0.172 0.187 -0.015 3.09e-02 0.171 0.182 -0.010 2.96e-02
CAD All.MultiPRS lassosum.PseudoVal 0.190 0.162 0.028 1.84e-05 0.189 0.160 0.030 3.91e-08
CAD LDpred1.MultiPRS lassosum.PseudoVal 0.173 0.162 0.010 1.33e-01 0.173 0.160 0.013 1.96e-02
CAD LDpred2.PseudoVal lassosum.PseudoVal 0.052 0.162 -0.110 2.80e-70 0.060 0.160 -0.100 1.07e-15
CAD DBSLMM.PseudoVal lassosum.PseudoVal 0.169 0.162 0.007 3.10e-02 0.163 0.160 0.003 6.13e-01
CAD LDpred1.Inf lassosum.PseudoVal 0.147 0.162 -0.015 1.76e-03 0.148 0.160 -0.012 2.16e-01
CAD LDpred2.Inf lassosum.PseudoVal 0.161 0.162 -0.001 7.73e-01 0.157 0.160 -0.003 7.76e-01
CAD lassosum.MultiPRS lassosum.PseudoVal 0.187 0.162 0.024 4.12e-04 0.182 0.160 0.022 1.35e-05
CAD LDpred1.10FCVal lassosum.PseudoVal 0.172 0.162 0.010 5.63e-04 0.171 0.160 0.012 3.17e-02
CAD lassosum.PseudoVal lassosum.PseudoVal 0.162 0.162 0.000 1.00e+00 0.160 0.160 0.000 1.00e+00
CAD LDpred2.MultiPRS lassosum.PseudoVal 0.190 0.162 0.028 6.60e-05 0.188 0.160 0.029 3.29e-08
CAD pT+clump.10FCVal lassosum.PseudoVal 0.139 0.162 -0.023 5.06e-12 0.126 0.160 -0.033 1.17e-06
CAD lassosum.10FCVal lassosum.PseudoVal 0.174 0.162 0.012 1.75e-04 0.171 0.160 0.011 9.49e-02
CAD LDpred2.10FCVal lassosum.PseudoVal 0.187 0.162 0.025 1.34e-17 0.184 0.160 0.024 2.54e-05
CAD SBayesR.PseudoVal lassosum.PseudoVal 0.164 0.162 0.002 4.93e-01 0.170 0.160 0.010 3.58e-02
CAD SBLUP.Inf lassosum.PseudoVal 0.161 0.162 -0.002 7.38e-01 0.156 0.160 -0.004 7.01e-01
CAD pT+clump.MultiPRS lassosum.PseudoVal 0.170 0.162 0.008 2.49e-01 0.166 0.160 0.006 3.14e-01
CAD All.MultiPRS lassosum.10FCVal 0.190 0.174 0.016 1.54e-02 0.189 0.171 0.019 8.48e-06
CAD LDpred1.MultiPRS lassosum.10FCVal 0.173 0.174 -0.002 7.85e-01 0.173 0.171 0.002 6.81e-01
CAD LDpred1.Inf lassosum.10FCVal 0.147 0.174 -0.027 1.52e-18 0.148 0.171 -0.023 2.10e-04
CAD LDpred2.Inf lassosum.10FCVal 0.161 0.174 -0.014 9.99e-09 0.157 0.171 -0.014 3.91e-03
CAD lassosum.MultiPRS lassosum.10FCVal 0.187 0.174 0.012 7.79e-02 0.182 0.171 0.011 1.16e-03
CAD DBSLMM.PseudoVal lassosum.10FCVal 0.169 0.174 -0.005 1.51e-01 0.163 0.171 -0.008 2.91e-01
CAD lassosum.PseudoVal lassosum.10FCVal 0.162 0.174 -0.012 1.75e-04 0.160 0.171 -0.011 9.49e-02
CAD LDpred2.MultiPRS lassosum.10FCVal 0.190 0.174 0.015 2.68e-02 0.188 0.171 0.018 8.01e-06
CAD pT+clump.10FCVal lassosum.10FCVal 0.139 0.174 -0.036 5.49e-22 0.126 0.171 -0.044 2.29e-09
CAD lassosum.10FCVal lassosum.10FCVal 0.174 0.174 0.000 1.00e+00 0.171 0.171 0.000 1.00e+00
CAD LDpred2.10FCVal lassosum.10FCVal 0.187 0.174 0.012 2.99e-12 0.184 0.171 0.013 1.68e-04
CAD SBayesR.PseudoVal lassosum.10FCVal 0.164 0.174 -0.011 4.67e-03 0.170 0.171 -0.001 9.32e-01
CAD LDpred2.PseudoVal lassosum.10FCVal 0.052 0.174 -0.122 6.34e-90 0.060 0.171 -0.111 8.09e-20
CAD SBLUP.Inf lassosum.10FCVal 0.161 0.174 -0.014 4.45e-09 0.156 0.171 -0.015 1.92e-03
CAD pT+clump.MultiPRS lassosum.10FCVal 0.170 0.174 -0.004 5.35e-01 0.166 0.171 -0.005 4.49e-01
CAD LDpred1.10FCVal lassosum.10FCVal 0.172 0.174 -0.003 3.55e-01 0.171 0.171 0.001 9.02e-01
CAD DBSLMM.PseudoVal LDpred1.MultiPRS 0.169 0.173 -0.003 6.28e-01 0.163 0.173 -0.010 7.89e-02
CAD LDpred2.MultiPRS LDpred1.MultiPRS 0.190 0.173 0.017 1.30e-02 0.188 0.173 0.015 1.52e-04
CAD pT+clump.10FCVal LDpred1.MultiPRS 0.139 0.173 -0.034 1.06e-06 0.126 0.173 -0.046 9.11e-09
CAD lassosum.10FCVal LDpred1.MultiPRS 0.174 0.173 0.002 7.85e-01 0.171 0.173 -0.002 6.81e-01
CAD lassosum.PseudoVal LDpred1.MultiPRS 0.162 0.173 -0.010 1.33e-01 0.160 0.173 -0.013 1.96e-02
CAD All.MultiPRS LDpred1.MultiPRS 0.190 0.173 0.018 1.02e-02 0.189 0.173 0.017 1.44e-04
CAD LDpred1.MultiPRS LDpred1.MultiPRS 0.173 0.173 0.000 1.00e+00 0.173 0.173 0.000 1.00e+00
CAD LDpred2.PseudoVal LDpred1.MultiPRS 0.052 0.173 -0.121 9.77e-67 0.060 0.173 -0.113 3.87e-20
CAD SBLUP.Inf LDpred1.MultiPRS 0.161 0.173 -0.012 8.40e-02 0.156 0.173 -0.017 1.17e-02
CAD LDpred1.Inf LDpred1.MultiPRS 0.147 0.173 -0.025 2.69e-04 0.148 0.173 -0.025 5.30e-06
CAD LDpred2.Inf LDpred1.MultiPRS 0.161 0.173 -0.012 8.91e-02 0.157 0.173 -0.016 1.87e-02
CAD lassosum.MultiPRS LDpred1.MultiPRS 0.187 0.173 0.014 4.12e-02 0.182 0.173 0.009 5.62e-02
CAD LDpred1.10FCVal LDpred1.MultiPRS 0.172 0.173 -0.001 9.00e-01 0.171 0.173 -0.002 9.11e-02
CAD pT+clump.MultiPRS LDpred1.MultiPRS 0.170 0.173 -0.002 7.29e-01 0.166 0.173 -0.007 2.48e-01
CAD SBayesR.PseudoVal LDpred1.MultiPRS 0.164 0.173 -0.009 2.08e-01 0.170 0.173 -0.003 5.54e-01
CAD LDpred2.10FCVal LDpred1.MultiPRS 0.187 0.173 0.014 3.69e-02 0.184 0.173 0.011 6.92e-03
CAD All.MultiPRS LDpred1.Inf 0.190 0.147 0.043 1.02e-10 0.189 0.148 0.042 6.41e-10
CAD LDpred1.Inf LDpred1.Inf 0.147 0.147 0.000 1.00e+00 0.148 0.148 0.000 1.00e+00
CAD LDpred2.Inf LDpred1.Inf 0.161 0.147 0.013 4.92e-09 0.157 0.148 0.009 4.81e-02
CAD DBSLMM.PseudoVal LDpred1.Inf 0.169 0.147 0.022 2.50e-07 0.163 0.148 0.015 7.54e-02
CAD lassosum.PseudoVal LDpred1.Inf 0.162 0.147 0.015 1.76e-03 0.160 0.148 0.012 2.16e-01
CAD LDpred2.MultiPRS LDpred1.Inf 0.190 0.147 0.042 9.71e-10 0.188 0.148 0.040 4.12e-10
CAD pT+clump.10FCVal LDpred1.Inf 0.139 0.147 -0.009 6.58e-02 0.126 0.148 -0.021 2.25e-02
CAD lassosum.10FCVal LDpred1.Inf 0.174 0.147 0.027 1.52e-18 0.171 0.148 0.023 2.10e-04
CAD LDpred2.10FCVal LDpred1.Inf 0.187 0.147 0.040 1.62e-40 0.184 0.148 0.036 8.85e-10
CAD SBayesR.PseudoVal LDpred1.Inf 0.164 0.147 0.017 2.38e-04 0.170 0.148 0.022 1.36e-02
CAD LDpred1.MultiPRS LDpred1.Inf 0.173 0.147 0.025 2.69e-04 0.173 0.148 0.025 5.30e-06
CAD LDpred2.PseudoVal LDpred1.Inf 0.052 0.147 -0.095 1.55e-52 0.060 0.148 -0.088 1.73e-12
CAD SBLUP.Inf LDpred1.Inf 0.161 0.147 0.013 4.83e-09 0.156 0.148 0.008 7.19e-02
CAD pT+clump.MultiPRS LDpred1.Inf 0.170 0.147 0.023 1.01e-03 0.166 0.148 0.018 2.49e-02
CAD lassosum.MultiPRS LDpred1.Inf 0.187 0.147 0.039 1.45e-08 0.182 0.148 0.034 5.03e-07
CAD LDpred1.10FCVal LDpred1.Inf 0.172 0.147 0.024 3.18e-15 0.171 0.148 0.023 1.49e-04
CAD LDpred1.Inf LDpred1.10FCVal 0.147 0.172 -0.024 3.18e-15 0.148 0.171 -0.023 1.49e-04
CAD DBSLMM.PseudoVal LDpred1.10FCVal 0.169 0.172 -0.002 3.80e-01 0.163 0.171 -0.008 1.33e-01
CAD lassosum.PseudoVal LDpred1.10FCVal 0.162 0.172 -0.010 5.63e-04 0.160 0.171 -0.012 3.17e-02
CAD LDpred2.MultiPRS LDpred1.10FCVal 0.190 0.172 0.018 8.95e-03 0.188 0.171 0.017 5.89e-05
CAD pT+clump.10FCVal LDpred1.10FCVal 0.139 0.172 -0.033 4.70e-16 0.126 0.171 -0.045 3.09e-08
CAD lassosum.10FCVal LDpred1.10FCVal 0.174 0.172 0.003 3.55e-01 0.171 0.171 -0.001 9.02e-01
CAD LDpred2.10FCVal LDpred1.10FCVal 0.187 0.172 0.015 4.60e-12 0.184 0.171 0.013 3.67e-03
CAD All.MultiPRS LDpred1.10FCVal 0.190 0.172 0.019 4.53e-03 0.189 0.171 0.018 5.44e-05
CAD LDpred1.MultiPRS LDpred1.10FCVal 0.173 0.172 0.001 9.00e-01 0.173 0.171 0.002 9.11e-02
CAD LDpred2.PseudoVal LDpred1.10FCVal 0.052 0.172 -0.120 6.93e-83 0.060 0.171 -0.112 2.11e-19
CAD SBLUP.Inf LDpred1.10FCVal 0.161 0.172 -0.011 2.07e-03 0.156 0.171 -0.015 3.39e-02
CAD pT+clump.MultiPRS LDpred1.10FCVal 0.170 0.172 -0.002 8.24e-01 0.166 0.171 -0.005 3.74e-01
CAD LDpred2.Inf LDpred1.10FCVal 0.161 0.172 -0.011 2.84e-03 0.157 0.171 -0.014 4.90e-02
CAD lassosum.MultiPRS LDpred1.10FCVal 0.187 0.172 0.015 3.09e-02 0.182 0.171 0.010 2.96e-02
CAD LDpred1.10FCVal LDpred1.10FCVal 0.172 0.172 0.000 1.00e+00 0.171 0.171 0.000 1.00e+00
CAD SBayesR.PseudoVal LDpred1.10FCVal 0.164 0.172 -0.008 1.06e-03 0.170 0.171 -0.001 7.73e-01
CAD LDpred2.MultiPRS LDpred2.MultiPRS 0.190 0.190 0.000 1.00e+00 0.188 0.188 0.000 1.00e+00
CAD lassosum.PseudoVal LDpred2.MultiPRS 0.162 0.190 -0.028 6.60e-05 0.160 0.188 -0.029 3.29e-08
CAD All.MultiPRS LDpred2.MultiPRS 0.190 0.190 0.001 9.30e-01 0.189 0.188 0.001 5.05e-01
CAD LDpred1.MultiPRS LDpred2.MultiPRS 0.173 0.190 -0.017 1.30e-02 0.173 0.188 -0.015 1.52e-04
CAD DBSLMM.PseudoVal LDpred2.MultiPRS 0.169 0.190 -0.020 3.03e-03 0.163 0.188 -0.025 8.10e-07
CAD LDpred1.Inf LDpred2.MultiPRS 0.147 0.190 -0.042 9.71e-10 0.148 0.188 -0.040 4.12e-10
CAD LDpred2.Inf LDpred2.MultiPRS 0.161 0.190 -0.029 3.03e-05 0.157 0.188 -0.031 2.95e-09
CAD lassosum.MultiPRS LDpred2.MultiPRS 0.187 0.190 -0.003 6.53e-01 0.182 0.188 -0.007 1.93e-02
CAD LDpred1.10FCVal LDpred2.MultiPRS 0.172 0.190 -0.018 8.95e-03 0.171 0.188 -0.017 5.89e-05
CAD pT+clump.MultiPRS LDpred2.MultiPRS 0.170 0.190 -0.020 4.61e-03 0.166 0.188 -0.022 7.91e-06
CAD SBayesR.PseudoVal LDpred2.MultiPRS 0.164 0.190 -0.026 1.78e-04 0.170 0.188 -0.018 5.37e-04
CAD pT+clump.10FCVal LDpred2.MultiPRS 0.139 0.190 -0.051 1.65e-13 0.126 0.188 -0.062 6.16e-18
CAD lassosum.10FCVal LDpred2.MultiPRS 0.174 0.190 -0.015 2.68e-02 0.171 0.188 -0.018 8.01e-06
CAD LDpred2.10FCVal LDpred2.MultiPRS 0.187 0.190 -0.003 6.85e-01 0.184 0.188 -0.004 2.13e-03
CAD LDpred2.PseudoVal LDpred2.MultiPRS 0.052 0.190 -0.138 7.34e-87 0.060 0.188 -0.129 1.75e-27
CAD SBLUP.Inf LDpred2.MultiPRS 0.161 0.190 -0.029 2.66e-05 0.156 0.188 -0.032 9.35e-10
CAD LDpred2.MultiPRS LDpred2.10FCVal 0.190 0.187 0.003 6.85e-01 0.188 0.184 0.004 2.13e-03
CAD pT+clump.10FCVal LDpred2.10FCVal 0.139 0.187 -0.048 2.20e-38 0.126 0.184 -0.058 7.14e-15
CAD lassosum.PseudoVal LDpred2.10FCVal 0.162 0.187 -0.025 1.34e-17 0.160 0.184 -0.024 2.54e-05
CAD All.MultiPRS LDpred2.10FCVal 0.190 0.187 0.003 6.02e-01 0.189 0.184 0.005 2.23e-02
CAD LDpred1.MultiPRS LDpred2.10FCVal 0.173 0.187 -0.014 3.69e-02 0.173 0.184 -0.011 6.92e-03
CAD LDpred2.PseudoVal LDpred2.10FCVal 0.052 0.187 -0.135 2.92e-117 0.060 0.184 -0.124 3.62e-26
CAD DBSLMM.PseudoVal LDpred2.10FCVal 0.169 0.187 -0.018 1.17e-11 0.163 0.184 -0.021 5.78e-05
CAD LDpred1.Inf LDpred2.10FCVal 0.147 0.187 -0.040 1.62e-40 0.148 0.184 -0.036 8.85e-10
CAD LDpred2.Inf LDpred2.10FCVal 0.161 0.187 -0.026 2.29e-31 0.157 0.184 -0.027 1.93e-09
CAD lassosum.MultiPRS LDpred2.10FCVal 0.187 0.187 0.000 9.65e-01 0.182 0.184 -0.002 4.28e-01
CAD LDpred1.10FCVal LDpred2.10FCVal 0.172 0.187 -0.015 4.60e-12 0.171 0.184 -0.013 3.67e-03
CAD pT+clump.MultiPRS LDpred2.10FCVal 0.170 0.187 -0.017 1.50e-02 0.166 0.184 -0.018 4.99e-04
CAD SBayesR.PseudoVal LDpred2.10FCVal 0.164 0.187 -0.023 8.35e-16 0.170 0.184 -0.014 1.47e-02
CAD lassosum.10FCVal LDpred2.10FCVal 0.174 0.187 -0.012 2.99e-12 0.171 0.184 -0.013 1.68e-04
CAD LDpred2.10FCVal LDpred2.10FCVal 0.187 0.187 0.000 1.00e+00 0.184 0.184 0.000 1.00e+00
CAD SBLUP.Inf LDpred2.10FCVal 0.161 0.187 -0.026 4.48e-32 0.156 0.184 -0.028 4.55e-10
CAD LDpred2.MultiPRS LDpred2.PseudoVal 0.190 0.052 0.138 7.34e-87 0.188 0.060 0.129 1.75e-27
CAD lassosum.PseudoVal LDpred2.PseudoVal 0.162 0.052 0.110 2.80e-70 0.160 0.060 0.100 1.07e-15
CAD All.MultiPRS LDpred2.PseudoVal 0.190 0.052 0.138 1.89e-90 0.189 0.060 0.130 9.45e-28
CAD LDpred1.MultiPRS LDpred2.PseudoVal 0.173 0.052 0.121 9.77e-67 0.173 0.060 0.113 3.87e-20
CAD DBSLMM.PseudoVal LDpred2.PseudoVal 0.169 0.052 0.117 1.05e-81 0.163 0.060 0.103 6.58e-17
CAD LDpred1.Inf LDpred2.PseudoVal 0.147 0.052 0.095 1.55e-52 0.148 0.060 0.088 1.73e-12
CAD LDpred2.Inf LDpred2.PseudoVal 0.161 0.052 0.109 8.61e-70 0.157 0.060 0.097 3.76e-15
CAD lassosum.MultiPRS LDpred2.PseudoVal 0.187 0.052 0.135 2.19e-82 0.182 0.060 0.122 4.64e-23
CAD LDpred1.10FCVal LDpred2.PseudoVal 0.172 0.052 0.120 6.93e-83 0.171 0.060 0.112 2.11e-19
CAD pT+clump.MultiPRS LDpred2.PseudoVal 0.170 0.052 0.118 3.02e-64 0.166 0.060 0.106 1.72e-19
CAD SBayesR.PseudoVal LDpred2.PseudoVal 0.164 0.052 0.112 8.19e-77 0.170 0.060 0.110 7.78e-20
CAD pT+clump.10FCVal LDpred2.PseudoVal 0.139 0.052 0.087 3.89e-49 0.126 0.060 0.067 1.49e-08
CAD lassosum.10FCVal LDpred2.PseudoVal 0.174 0.052 0.122 6.34e-90 0.171 0.060 0.111 8.09e-20
CAD LDpred2.10FCVal LDpred2.PseudoVal 0.187 0.052 0.135 2.92e-117 0.184 0.060 0.124 3.62e-26
CAD LDpred2.PseudoVal LDpred2.PseudoVal 0.052 0.052 0.000 1.00e+00 0.060 0.060 0.000 1.00e+00
CAD SBLUP.Inf LDpred2.PseudoVal 0.161 0.052 0.109 2.79e-68 0.156 0.060 0.096 1.28e-14
CAD DBSLMM.PseudoVal LDpred2.Inf 0.169 0.161 0.008 3.55e-02 0.163 0.157 0.006 4.59e-01
CAD LDpred2.MultiPRS LDpred2.Inf 0.190 0.161 0.029 3.03e-05 0.188 0.157 0.031 2.95e-09
CAD pT+clump.10FCVal LDpred2.Inf 0.139 0.161 -0.022 9.96e-07 0.126 0.157 -0.030 7.51e-04
CAD lassosum.10FCVal LDpred2.Inf 0.174 0.161 0.014 9.99e-09 0.171 0.157 0.014 3.91e-03
CAD lassosum.PseudoVal LDpred2.Inf 0.162 0.161 0.001 7.73e-01 0.160 0.157 0.003 7.76e-01
CAD All.MultiPRS LDpred2.Inf 0.190 0.161 0.029 7.72e-06 0.189 0.157 0.033 8.81e-09
CAD LDpred1.MultiPRS LDpred2.Inf 0.173 0.161 0.012 8.91e-02 0.173 0.157 0.016 1.87e-02
CAD LDpred2.PseudoVal LDpred2.Inf 0.052 0.161 -0.109 8.61e-70 0.060 0.157 -0.097 3.76e-15
CAD SBLUP.Inf LDpred2.Inf 0.161 0.161 0.000 6.43e-01 0.156 0.157 -0.001 2.91e-01
CAD LDpred1.Inf LDpred2.Inf 0.147 0.161 -0.013 4.92e-09 0.148 0.157 -0.009 4.81e-02
CAD LDpred2.Inf LDpred2.Inf 0.161 0.161 0.000 1.00e+00 0.157 0.157 0.000 1.00e+00
CAD lassosum.MultiPRS LDpred2.Inf 0.187 0.161 0.026 1.91e-04 0.182 0.157 0.025 1.16e-05
CAD LDpred1.10FCVal LDpred2.Inf 0.172 0.161 0.011 2.84e-03 0.171 0.157 0.014 4.90e-02
CAD pT+clump.MultiPRS LDpred2.Inf 0.170 0.161 0.009 1.77e-01 0.166 0.157 0.009 2.30e-01
CAD SBayesR.PseudoVal LDpred2.Inf 0.164 0.161 0.003 5.07e-01 0.170 0.157 0.013 1.56e-01
CAD LDpred2.10FCVal LDpred2.Inf 0.187 0.161 0.026 2.29e-31 0.184 0.157 0.027 1.93e-09
CAD All.MultiPRS pT+clump.MultiPRS 0.190 0.170 0.020 3.60e-03 0.189 0.166 0.024 4.50e-07
CAD LDpred1.MultiPRS pT+clump.MultiPRS 0.173 0.170 0.002 7.29e-01 0.173 0.166 0.007 2.48e-01
CAD LDpred2.PseudoVal pT+clump.MultiPRS 0.052 0.170 -0.118 3.02e-64 0.060 0.166 -0.106 1.72e-19
CAD DBSLMM.PseudoVal pT+clump.MultiPRS 0.169 0.170 -0.001 8.92e-01 0.163 0.166 -0.003 6.15e-01
CAD LDpred1.Inf pT+clump.MultiPRS 0.147 0.170 -0.023 1.01e-03 0.148 0.166 -0.018 2.49e-02
CAD LDpred2.Inf pT+clump.MultiPRS 0.161 0.170 -0.009 1.77e-01 0.157 0.166 -0.009 2.30e-01
CAD lassosum.MultiPRS pT+clump.MultiPRS 0.187 0.170 0.016 1.74e-02 0.182 0.166 0.016 1.48e-03
CAD LDpred1.10FCVal pT+clump.MultiPRS 0.172 0.170 0.002 8.24e-01 0.171 0.166 0.005 3.74e-01
CAD lassosum.PseudoVal pT+clump.MultiPRS 0.162 0.170 -0.008 2.49e-01 0.160 0.166 -0.006 3.14e-01
CAD LDpred2.MultiPRS pT+clump.MultiPRS 0.190 0.170 0.020 4.61e-03 0.188 0.166 0.022 7.91e-06
CAD pT+clump.10FCVal pT+clump.MultiPRS 0.139 0.170 -0.031 6.11e-06 0.126 0.166 -0.039 9.07e-11
CAD lassosum.10FCVal pT+clump.MultiPRS 0.174 0.170 0.004 5.35e-01 0.171 0.166 0.005 4.49e-01
CAD LDpred2.10FCVal pT+clump.MultiPRS 0.187 0.170 0.017 1.50e-02 0.184 0.166 0.018 4.99e-04
CAD SBayesR.PseudoVal pT+clump.MultiPRS 0.164 0.170 -0.006 3.63e-01 0.170 0.166 0.004 5.30e-01
CAD SBLUP.Inf pT+clump.MultiPRS 0.161 0.170 -0.010 1.68e-01 0.156 0.166 -0.010 1.81e-01
CAD pT+clump.MultiPRS pT+clump.MultiPRS 0.170 0.170 0.000 1.00e+00 0.166 0.166 0.000 1.00e+00
CAD lassosum.PseudoVal pT+clump.10FCVal 0.162 0.139 0.023 5.06e-12 0.160 0.126 0.033 1.17e-06
CAD All.MultiPRS pT+clump.10FCVal 0.190 0.139 0.052 8.34e-15 0.189 0.126 0.063 7.79e-18
CAD DBSLMM.PseudoVal pT+clump.10FCVal 0.169 0.139 0.031 2.73e-11 0.163 0.126 0.036 6.89e-05
CAD LDpred1.Inf pT+clump.10FCVal 0.147 0.139 0.009 6.58e-02 0.148 0.126 0.021 2.25e-02
CAD LDpred2.Inf pT+clump.10FCVal 0.161 0.139 0.022 9.96e-07 0.157 0.126 0.030 7.51e-04
CAD lassosum.MultiPRS pT+clump.10FCVal 0.187 0.139 0.048 5.13e-12 0.182 0.126 0.055 1.76e-13
CAD LDpred1.10FCVal pT+clump.10FCVal 0.172 0.139 0.033 4.70e-16 0.171 0.126 0.045 3.09e-08
CAD pT+clump.MultiPRS pT+clump.10FCVal 0.170 0.139 0.031 6.11e-06 0.166 0.126 0.039 9.07e-11
CAD LDpred2.MultiPRS pT+clump.10FCVal 0.190 0.139 0.051 1.65e-13 0.188 0.126 0.062 6.16e-18
CAD pT+clump.10FCVal pT+clump.10FCVal 0.139 0.139 0.000 1.00e+00 0.126 0.126 0.000 1.00e+00
CAD lassosum.10FCVal pT+clump.10FCVal 0.174 0.139 0.036 5.49e-22 0.171 0.126 0.044 2.29e-09
CAD LDpred2.10FCVal pT+clump.10FCVal 0.187 0.139 0.048 2.20e-38 0.184 0.126 0.058 7.14e-15
CAD SBayesR.PseudoVal pT+clump.10FCVal 0.164 0.139 0.025 6.34e-09 0.170 0.126 0.044 5.28e-07
CAD LDpred1.MultiPRS pT+clump.10FCVal 0.173 0.139 0.034 1.06e-06 0.173 0.126 0.046 9.11e-09
CAD LDpred2.PseudoVal pT+clump.10FCVal 0.052 0.139 -0.087 3.89e-49 0.060 0.126 -0.067 1.49e-08
CAD SBLUP.Inf pT+clump.10FCVal 0.161 0.139 0.022 1.02e-06 0.156 0.126 0.030 9.66e-04
CAD LDpred1.Inf SBayesR.PseudoVal 0.147 0.164 -0.017 2.38e-04 0.148 0.170 -0.022 1.36e-02
CAD DBSLMM.PseudoVal SBayesR.PseudoVal 0.169 0.164 0.005 3.49e-02 0.163 0.170 -0.007 1.66e-01
CAD lassosum.PseudoVal SBayesR.PseudoVal 0.162 0.164 -0.002 4.93e-01 0.160 0.170 -0.010 3.58e-02
CAD LDpred2.MultiPRS SBayesR.PseudoVal 0.190 0.164 0.026 1.78e-04 0.188 0.170 0.018 5.37e-04
CAD pT+clump.10FCVal SBayesR.PseudoVal 0.139 0.164 -0.025 6.34e-09 0.126 0.170 -0.044 5.28e-07
CAD lassosum.10FCVal SBayesR.PseudoVal 0.174 0.164 0.011 4.67e-03 0.171 0.170 0.001 9.32e-01
CAD LDpred2.10FCVal SBayesR.PseudoVal 0.187 0.164 0.023 8.35e-16 0.184 0.170 0.014 1.47e-02
CAD All.MultiPRS SBayesR.PseudoVal 0.190 0.164 0.026 5.85e-05 0.189 0.170 0.019 2.94e-04
CAD LDpred1.MultiPRS SBayesR.PseudoVal 0.173 0.164 0.009 2.08e-01 0.173 0.170 0.003 5.54e-01
CAD LDpred2.PseudoVal SBayesR.PseudoVal 0.052 0.164 -0.112 8.19e-77 0.060 0.170 -0.110 7.78e-20
CAD SBLUP.Inf SBayesR.PseudoVal 0.161 0.164 -0.003 4.77e-01 0.156 0.170 -0.014 1.26e-01
CAD pT+clump.MultiPRS SBayesR.PseudoVal 0.170 0.164 0.006 3.63e-01 0.166 0.170 -0.004 5.30e-01
CAD LDpred2.Inf SBayesR.PseudoVal 0.161 0.164 -0.003 5.07e-01 0.157 0.170 -0.013 1.56e-01
CAD lassosum.MultiPRS SBayesR.PseudoVal 0.187 0.164 0.023 1.02e-03 0.182 0.170 0.012 4.36e-02
CAD LDpred1.10FCVal SBayesR.PseudoVal 0.172 0.164 0.008 1.06e-03 0.171 0.170 0.001 7.73e-01
CAD SBayesR.PseudoVal SBayesR.PseudoVal 0.164 0.164 0.000 1.00e+00 0.170 0.170 0.000 1.00e+00
CAD All.MultiPRS SBLUP.Inf 0.190 0.161 0.030 6.73e-06 0.189 0.156 0.033 3.43e-09
CAD LDpred1.Inf SBLUP.Inf 0.147 0.161 -0.013 4.83e-09 0.148 0.156 -0.008 7.19e-02
CAD LDpred2.Inf SBLUP.Inf 0.161 0.161 0.000 6.43e-01 0.157 0.156 0.001 2.91e-01
CAD DBSLMM.PseudoVal SBLUP.Inf 0.169 0.161 0.009 2.97e-02 0.163 0.156 0.007 3.88e-01
CAD lassosum.PseudoVal SBLUP.Inf 0.162 0.161 0.002 7.38e-01 0.160 0.156 0.004 7.01e-01
CAD LDpred2.MultiPRS SBLUP.Inf 0.190 0.161 0.029 2.66e-05 0.188 0.156 0.032 9.35e-10
CAD pT+clump.10FCVal SBLUP.Inf 0.139 0.161 -0.022 1.02e-06 0.126 0.156 -0.030 9.66e-04
CAD lassosum.10FCVal SBLUP.Inf 0.174 0.161 0.014 4.45e-09 0.171 0.156 0.015 1.92e-03
CAD LDpred2.10FCVal SBLUP.Inf 0.187 0.161 0.026 4.48e-32 0.184 0.156 0.028 4.55e-10
CAD SBayesR.PseudoVal SBLUP.Inf 0.164 0.161 0.003 4.77e-01 0.170 0.156 0.014 1.26e-01
CAD LDpred1.MultiPRS SBLUP.Inf 0.173 0.161 0.012 8.40e-02 0.173 0.156 0.017 1.17e-02
CAD LDpred2.PseudoVal SBLUP.Inf 0.052 0.161 -0.109 2.79e-68 0.060 0.156 -0.096 1.28e-14
CAD SBLUP.Inf SBLUP.Inf 0.161 0.161 0.000 1.00e+00 0.156 0.156 0.000 1.00e+00
CAD pT+clump.MultiPRS SBLUP.Inf 0.170 0.161 0.010 1.68e-01 0.166 0.156 0.010 1.81e-01
CAD lassosum.MultiPRS SBLUP.Inf 0.187 0.161 0.026 1.70e-04 0.182 0.156 0.026 4.54e-06
CAD LDpred1.10FCVal SBLUP.Inf 0.172 0.161 0.011 2.07e-03 0.171 0.156 0.015 3.39e-02
IBD lassosum.PseudoVal All.MultiPRS 0.133 0.146 -0.013 6.05e-02 0.140 0.152 -0.012 4.36e-03
IBD All.MultiPRS All.MultiPRS 0.146 0.146 0.000 1.00e+00 0.152 0.152 0.000 1.00e+00
IBD DBSLMM.PseudoVal All.MultiPRS 0.130 0.146 -0.016 1.87e-02 0.136 0.152 -0.016 6.91e-04
IBD LDpred1.Inf All.MultiPRS 0.098 0.146 -0.048 8.57e-12 0.103 0.152 -0.049 4.15e-10
IBD LDpred2.Inf All.MultiPRS 0.096 0.146 -0.050 8.73e-13 0.100 0.152 -0.052 8.29e-11
IBD lassosum.MultiPRS All.MultiPRS 0.144 0.146 -0.003 2.09e-02 0.148 0.152 -0.004 7.23e-02
IBD LDpred1.10FCVal All.MultiPRS 0.129 0.146 -0.017 1.47e-02 0.137 0.152 -0.015 2.38e-03
IBD pT+clump.MultiPRS All.MultiPRS 0.127 0.146 -0.019 7.14e-03 0.136 0.152 -0.016 9.79e-04
IBD LDpred2.MultiPRS All.MultiPRS 0.143 0.146 -0.004 2.30e-04 0.150 0.152 -0.002 4.02e-01
IBD pT+clump.10FCVal All.MultiPRS 0.111 0.146 -0.035 4.48e-07 0.109 0.152 -0.043 1.80e-10
IBD lassosum.10FCVal All.MultiPRS 0.134 0.146 -0.012 8.34e-02 0.140 0.152 -0.011 6.29e-03
IBD LDpred2.10FCVal All.MultiPRS 0.143 0.146 -0.003 6.41e-01 0.149 0.152 -0.003 2.76e-01
IBD SBayesR.PseudoVal All.MultiPRS 0.128 0.146 -0.019 7.54e-03 0.143 0.152 -0.009 6.34e-02
IBD LDpred1.MultiPRS All.MultiPRS 0.130 0.146 -0.016 3.11e-12 0.138 0.152 -0.014 2.74e-03
IBD LDpred2.PseudoVal All.MultiPRS 0.140 0.146 -0.006 3.67e-01 0.145 0.152 -0.007 2.11e-02
IBD SBLUP.Inf All.MultiPRS 0.097 0.146 -0.049 2.97e-12 0.102 0.152 -0.050 2.75e-10
IBD LDpred2.MultiPRS DBSLMM.PseudoVal 0.143 0.130 0.013 6.62e-02 0.150 0.136 0.014 2.22e-03
IBD pT+clump.10FCVal DBSLMM.PseudoVal 0.111 0.130 -0.019 2.68e-07 0.109 0.136 -0.027 1.73e-04
IBD lassosum.PseudoVal DBSLMM.PseudoVal 0.133 0.130 0.003 2.54e-01 0.140 0.136 0.004 5.21e-01
IBD All.MultiPRS DBSLMM.PseudoVal 0.146 0.130 0.016 1.87e-02 0.152 0.136 0.016 6.91e-04
IBD LDpred1.MultiPRS DBSLMM.PseudoVal 0.130 0.130 0.000 9.65e-01 0.138 0.136 0.002 6.86e-01
IBD LDpred2.PseudoVal DBSLMM.PseudoVal 0.140 0.130 0.010 2.82e-04 0.145 0.136 0.010 8.69e-02
IBD DBSLMM.PseudoVal DBSLMM.PseudoVal 0.130 0.130 0.000 1.00e+00 0.136 0.136 0.000 1.00e+00
IBD LDpred1.Inf DBSLMM.PseudoVal 0.098 0.130 -0.031 2.52e-13 0.103 0.136 -0.033 1.32e-04
IBD LDpred2.Inf DBSLMM.PseudoVal 0.096 0.130 -0.034 1.38e-14 0.100 0.136 -0.036 4.87e-05
IBD lassosum.MultiPRS DBSLMM.PseudoVal 0.144 0.130 0.014 4.77e-02 0.148 0.136 0.012 2.08e-02
IBD LDpred1.10FCVal DBSLMM.PseudoVal 0.129 0.130 -0.001 8.40e-01 0.137 0.136 0.001 8.45e-01
IBD pT+clump.MultiPRS DBSLMM.PseudoVal 0.127 0.130 -0.002 7.41e-01 0.136 0.136 0.000 9.70e-01
IBD SBayesR.PseudoVal DBSLMM.PseudoVal 0.128 0.130 -0.002 4.59e-01 0.143 0.136 0.008 2.05e-01
IBD lassosum.10FCVal DBSLMM.PseudoVal 0.134 0.130 0.004 1.85e-01 0.140 0.136 0.005 4.80e-01
IBD LDpred2.10FCVal DBSLMM.PseudoVal 0.143 0.130 0.013 3.34e-07 0.149 0.136 0.013 9.22e-03
IBD SBLUP.Inf DBSLMM.PseudoVal 0.097 0.130 -0.033 1.41e-13 0.102 0.136 -0.034 1.24e-04
IBD All.MultiPRS lassosum.MultiPRS 0.146 0.144 0.003 2.09e-02 0.152 0.148 0.004 7.23e-02
IBD LDpred1.MultiPRS lassosum.MultiPRS 0.130 0.144 -0.014 3.12e-08 0.138 0.148 -0.010 4.54e-02
IBD LDpred1.Inf lassosum.MultiPRS 0.098 0.144 -0.045 1.03e-10 0.103 0.148 -0.045 1.04e-08
IBD LDpred2.Inf lassosum.MultiPRS 0.096 0.144 -0.048 1.18e-11 0.100 0.148 -0.048 2.35e-09
IBD lassosum.MultiPRS lassosum.MultiPRS 0.144 0.144 0.000 1.00e+00 0.148 0.148 0.000 1.00e+00
IBD DBSLMM.PseudoVal lassosum.MultiPRS 0.130 0.144 -0.014 4.77e-02 0.136 0.148 -0.012 2.08e-02
IBD lassosum.PseudoVal lassosum.MultiPRS 0.133 0.144 -0.010 1.33e-01 0.140 0.148 -0.008 2.65e-02
IBD LDpred2.MultiPRS lassosum.MultiPRS 0.143 0.144 -0.001 5.57e-01 0.150 0.148 0.002 4.55e-01
IBD pT+clump.10FCVal lassosum.MultiPRS 0.111 0.144 -0.033 2.95e-06 0.109 0.148 -0.039 5.45e-08
IBD lassosum.10FCVal lassosum.MultiPRS 0.134 0.144 -0.009 1.75e-01 0.140 0.148 -0.007 2.94e-02
IBD LDpred2.10FCVal lassosum.MultiPRS 0.143 0.144 -0.001 9.27e-01 0.149 0.148 0.001 6.78e-01
IBD SBayesR.PseudoVal lassosum.MultiPRS 0.128 0.144 -0.016 2.15e-02 0.143 0.148 -0.004 3.78e-01
IBD LDpred2.PseudoVal lassosum.MultiPRS 0.140 0.144 -0.004 5.98e-01 0.145 0.148 -0.002 5.49e-01
IBD SBLUP.Inf lassosum.MultiPRS 0.097 0.144 -0.046 3.76e-11 0.102 0.148 -0.046 6.21e-09
IBD pT+clump.MultiPRS lassosum.MultiPRS 0.127 0.144 -0.016 2.06e-02 0.136 0.148 -0.012 2.19e-02
IBD LDpred1.10FCVal lassosum.MultiPRS 0.129 0.144 -0.014 3.86e-02 0.137 0.148 -0.011 3.26e-02
IBD All.MultiPRS lassosum.PseudoVal 0.146 0.133 0.013 6.05e-02 0.152 0.140 0.012 4.36e-03
IBD LDpred1.MultiPRS lassosum.PseudoVal 0.130 0.133 -0.003 6.61e-01 0.138 0.140 -0.001 8.25e-01
IBD LDpred2.PseudoVal lassosum.PseudoVal 0.140 0.133 0.007 2.66e-04 0.145 0.140 0.006 1.22e-01
IBD DBSLMM.PseudoVal lassosum.PseudoVal 0.130 0.133 -0.003 2.54e-01 0.136 0.140 -0.004 5.21e-01
IBD LDpred1.Inf lassosum.PseudoVal 0.098 0.133 -0.035 1.92e-12 0.103 0.140 -0.037 1.94e-04
IBD LDpred2.Inf lassosum.PseudoVal 0.096 0.133 -0.037 3.13e-13 0.100 0.140 -0.039 9.86e-05
IBD lassosum.MultiPRS lassosum.PseudoVal 0.144 0.133 0.010 1.33e-01 0.148 0.140 0.008 2.65e-02
IBD LDpred1.10FCVal lassosum.PseudoVal 0.129 0.133 -0.004 2.45e-01 0.137 0.140 -0.003 7.02e-01
IBD lassosum.PseudoVal lassosum.PseudoVal 0.133 0.133 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
IBD LDpred2.MultiPRS lassosum.PseudoVal 0.143 0.133 0.010 1.74e-01 0.150 0.140 0.011 8.21e-03
IBD pT+clump.10FCVal lassosum.PseudoVal 0.111 0.133 -0.022 2.09e-11 0.109 0.140 -0.031 2.25e-06
IBD lassosum.10FCVal lassosum.PseudoVal 0.134 0.133 0.001 5.89e-01 0.140 0.140 0.001 8.09e-01
IBD LDpred2.10FCVal lassosum.PseudoVal 0.143 0.133 0.010 6.59e-06 0.149 0.140 0.010 2.60e-02
IBD SBayesR.PseudoVal lassosum.PseudoVal 0.128 0.133 -0.006 3.33e-02 0.143 0.140 0.004 4.66e-01
IBD SBLUP.Inf lassosum.PseudoVal 0.097 0.133 -0.036 1.77e-12 0.102 0.140 -0.037 2.07e-04
IBD pT+clump.MultiPRS lassosum.PseudoVal 0.127 0.133 -0.006 4.17e-01 0.136 0.140 -0.004 5.45e-01
IBD All.MultiPRS lassosum.10FCVal 0.146 0.134 0.012 8.34e-02 0.152 0.140 0.011 6.29e-03
IBD LDpred1.MultiPRS lassosum.10FCVal 0.130 0.134 -0.004 5.61e-01 0.138 0.140 -0.002 6.72e-01
IBD LDpred1.Inf lassosum.10FCVal 0.098 0.134 -0.036 2.06e-17 0.103 0.140 -0.037 8.33e-06
IBD LDpred2.Inf lassosum.10FCVal 0.096 0.134 -0.038 5.63e-19 0.100 0.140 -0.040 2.32e-06
IBD lassosum.MultiPRS lassosum.10FCVal 0.144 0.134 0.009 1.75e-01 0.148 0.140 0.007 2.94e-02
IBD DBSLMM.PseudoVal lassosum.10FCVal 0.130 0.134 -0.004 1.85e-01 0.136 0.140 -0.005 4.80e-01
IBD lassosum.PseudoVal lassosum.10FCVal 0.133 0.134 -0.001 5.89e-01 0.140 0.140 -0.001 8.09e-01
IBD LDpred2.MultiPRS lassosum.10FCVal 0.143 0.134 0.008 2.24e-01 0.150 0.140 0.010 1.80e-02
IBD pT+clump.10FCVal lassosum.10FCVal 0.111 0.134 -0.023 6.20e-09 0.109 0.140 -0.032 5.42e-05
IBD lassosum.10FCVal lassosum.10FCVal 0.134 0.134 0.000 1.00e+00 0.140 0.140 0.000 1.00e+00
IBD LDpred2.10FCVal lassosum.10FCVal 0.143 0.134 0.009 2.90e-06 0.149 0.140 0.009 2.12e-02
IBD SBayesR.PseudoVal lassosum.10FCVal 0.128 0.134 -0.007 2.11e-02 0.143 0.140 0.003 6.16e-01
IBD LDpred2.PseudoVal lassosum.10FCVal 0.140 0.134 0.006 9.74e-03 0.145 0.140 0.005 2.78e-01
IBD SBLUP.Inf lassosum.10FCVal 0.097 0.134 -0.037 4.93e-18 0.102 0.140 -0.038 6.02e-06
IBD pT+clump.MultiPRS lassosum.10FCVal 0.127 0.134 -0.007 3.39e-01 0.136 0.140 -0.004 4.32e-01
IBD LDpred1.10FCVal lassosum.10FCVal 0.129 0.134 -0.005 8.23e-02 0.137 0.140 -0.003 5.42e-01
IBD DBSLMM.PseudoVal LDpred1.MultiPRS 0.130 0.130 0.000 9.65e-01 0.136 0.138 -0.002 6.86e-01
IBD LDpred2.MultiPRS LDpred1.MultiPRS 0.143 0.130 0.013 8.80e-09 0.150 0.138 0.012 5.10e-03
IBD pT+clump.10FCVal LDpred1.MultiPRS 0.111 0.130 -0.019 6.27e-03 0.109 0.138 -0.030 3.59e-04
IBD lassosum.10FCVal LDpred1.MultiPRS 0.134 0.130 0.004 5.61e-01 0.140 0.138 0.002 6.72e-01
IBD lassosum.PseudoVal LDpred1.MultiPRS 0.133 0.130 0.003 6.61e-01 0.140 0.138 0.001 8.25e-01
IBD All.MultiPRS LDpred1.MultiPRS 0.146 0.130 0.016 3.11e-12 0.152 0.138 0.014 2.74e-03
IBD LDpred1.MultiPRS LDpred1.MultiPRS 0.130 0.130 0.000 1.00e+00 0.138 0.138 0.000 1.00e+00
IBD LDpred2.PseudoVal LDpred1.MultiPRS 0.140 0.130 0.010 1.57e-01 0.145 0.138 0.007 2.01e-01
IBD SBLUP.Inf LDpred1.MultiPRS 0.097 0.130 -0.033 2.98e-06 0.102 0.138 -0.036 1.27e-09
IBD LDpred1.Inf LDpred1.MultiPRS 0.098 0.130 -0.032 6.20e-06 0.103 0.138 -0.035 5.33e-12
IBD LDpred2.Inf LDpred1.MultiPRS 0.096 0.130 -0.034 1.29e-06 0.100 0.138 -0.038 1.94e-10
IBD lassosum.MultiPRS LDpred1.MultiPRS 0.144 0.130 0.014 3.12e-08 0.148 0.138 0.010 4.54e-02
IBD LDpred1.10FCVal LDpred1.MultiPRS 0.129 0.130 -0.001 8.96e-01 0.137 0.138 -0.001 4.56e-01
IBD pT+clump.MultiPRS LDpred1.MultiPRS 0.127 0.130 -0.003 7.08e-01 0.136 0.138 -0.002 7.07e-01
IBD SBayesR.PseudoVal LDpred1.MultiPRS 0.128 0.130 -0.002 7.21e-01 0.143 0.138 0.005 3.38e-01
IBD LDpred2.10FCVal LDpred1.MultiPRS 0.143 0.130 0.013 6.46e-02 0.149 0.138 0.011 4.92e-03
IBD All.MultiPRS LDpred1.Inf 0.146 0.098 0.048 8.57e-12 0.152 0.103 0.049 4.15e-10
IBD LDpred1.Inf LDpred1.Inf 0.098 0.098 0.000 1.00e+00 0.103 0.103 0.000 1.00e+00
IBD LDpred2.Inf LDpred1.Inf 0.096 0.098 -0.002 1.40e-01 0.100 0.103 -0.003 3.79e-01
IBD DBSLMM.PseudoVal LDpred1.Inf 0.130 0.098 0.031 2.52e-13 0.136 0.103 0.033 1.32e-04
IBD lassosum.PseudoVal LDpred1.Inf 0.133 0.098 0.035 1.92e-12 0.140 0.103 0.037 1.94e-04
IBD LDpred2.MultiPRS LDpred1.Inf 0.143 0.098 0.044 2.75e-10 0.150 0.103 0.047 2.87e-09
IBD pT+clump.10FCVal LDpred1.Inf 0.111 0.098 0.013 1.99e-02 0.109 0.103 0.006 6.03e-01
IBD lassosum.10FCVal LDpred1.Inf 0.134 0.098 0.036 2.06e-17 0.140 0.103 0.037 8.33e-06
IBD LDpred2.10FCVal LDpred1.Inf 0.143 0.098 0.045 7.19e-33 0.149 0.103 0.046 6.70e-10
IBD SBayesR.PseudoVal LDpred1.Inf 0.128 0.098 0.029 6.35e-12 0.143 0.103 0.040 2.28e-06
IBD LDpred1.MultiPRS LDpred1.Inf 0.130 0.098 0.032 6.20e-06 0.138 0.103 0.035 5.33e-12
IBD LDpred2.PseudoVal LDpred1.Inf 0.140 0.098 0.042 9.50e-20 0.145 0.103 0.042 3.57e-06
IBD SBLUP.Inf LDpred1.Inf 0.097 0.098 -0.001 4.92e-01 0.102 0.103 -0.001 7.84e-01
IBD pT+clump.MultiPRS LDpred1.Inf 0.127 0.098 0.029 3.14e-05 0.136 0.103 0.033 5.55e-05
IBD lassosum.MultiPRS LDpred1.Inf 0.144 0.098 0.045 1.03e-10 0.148 0.103 0.045 1.04e-08
IBD LDpred1.10FCVal LDpred1.Inf 0.129 0.098 0.031 9.32e-46 0.137 0.103 0.034 3.86e-15
IBD LDpred1.Inf LDpred1.10FCVal 0.098 0.129 -0.031 9.32e-46 0.103 0.137 -0.034 3.86e-15
IBD DBSLMM.PseudoVal LDpred1.10FCVal 0.130 0.129 0.001 8.40e-01 0.136 0.137 -0.001 8.45e-01
IBD lassosum.PseudoVal LDpred1.10FCVal 0.133 0.129 0.004 2.45e-01 0.140 0.137 0.003 7.02e-01
IBD LDpred2.MultiPRS LDpred1.10FCVal 0.143 0.129 0.013 5.42e-02 0.150 0.137 0.013 4.77e-03
IBD pT+clump.10FCVal LDpred1.10FCVal 0.111 0.129 -0.018 3.40e-05 0.109 0.137 -0.028 1.04e-03
IBD lassosum.10FCVal LDpred1.10FCVal 0.134 0.129 0.005 8.23e-02 0.140 0.137 0.003 5.42e-01
IBD LDpred2.10FCVal LDpred1.10FCVal 0.143 0.129 0.014 9.42e-11 0.149 0.137 0.012 3.99e-03
IBD All.MultiPRS LDpred1.10FCVal 0.146 0.129 0.017 1.47e-02 0.152 0.137 0.015 2.38e-03
IBD LDpred1.MultiPRS LDpred1.10FCVal 0.130 0.129 0.001 8.96e-01 0.138 0.137 0.001 4.56e-01
IBD LDpred2.PseudoVal LDpred1.10FCVal 0.140 0.129 0.011 4.25e-04 0.145 0.137 0.008 1.69e-01
IBD SBLUP.Inf LDpred1.10FCVal 0.097 0.129 -0.032 2.01e-32 0.102 0.137 -0.035 6.36e-11
IBD pT+clump.MultiPRS LDpred1.10FCVal 0.127 0.129 -0.002 8.08e-01 0.136 0.137 -0.001 8.72e-01
IBD LDpred2.Inf LDpred1.10FCVal 0.096 0.129 -0.033 1.12e-34 0.100 0.137 -0.037 6.92e-12
IBD lassosum.MultiPRS LDpred1.10FCVal 0.144 0.129 0.014 3.86e-02 0.148 0.137 0.011 3.26e-02
IBD LDpred1.10FCVal LDpred1.10FCVal 0.129 0.129 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
IBD SBayesR.PseudoVal LDpred1.10FCVal 0.128 0.129 -0.002 5.75e-01 0.143 0.137 0.006 2.63e-01
IBD LDpred2.MultiPRS LDpred2.MultiPRS 0.143 0.143 0.000 1.00e+00 0.150 0.150 0.000 1.00e+00
IBD lassosum.PseudoVal LDpred2.MultiPRS 0.133 0.143 -0.010 1.74e-01 0.140 0.150 -0.011 8.21e-03
IBD All.MultiPRS LDpred2.MultiPRS 0.146 0.143 0.004 2.30e-04 0.152 0.150 0.002 4.02e-01
IBD LDpred1.MultiPRS LDpred2.MultiPRS 0.130 0.143 -0.013 8.80e-09 0.138 0.150 -0.012 5.10e-03
IBD DBSLMM.PseudoVal LDpred2.MultiPRS 0.130 0.143 -0.013 6.62e-02 0.136 0.150 -0.014 2.22e-03
IBD LDpred1.Inf LDpred2.MultiPRS 0.098 0.143 -0.044 2.75e-10 0.103 0.150 -0.047 2.87e-09
IBD LDpred2.Inf LDpred2.MultiPRS 0.096 0.143 -0.047 3.28e-11 0.100 0.150 -0.050 4.79e-10
IBD lassosum.MultiPRS LDpred2.MultiPRS 0.144 0.143 0.001 5.57e-01 0.148 0.150 -0.002 4.55e-01
IBD LDpred1.10FCVal LDpred2.MultiPRS 0.129 0.143 -0.013 5.42e-02 0.137 0.150 -0.013 4.77e-03
IBD pT+clump.MultiPRS LDpred2.MultiPRS 0.127 0.143 -0.015 2.96e-02 0.136 0.150 -0.014 6.14e-03
IBD SBayesR.PseudoVal LDpred2.MultiPRS 0.128 0.143 -0.015 3.12e-02 0.143 0.150 -0.007 9.69e-02
IBD pT+clump.10FCVal LDpred2.MultiPRS 0.111 0.143 -0.032 5.89e-06 0.109 0.150 -0.042 1.01e-09
IBD lassosum.10FCVal LDpred2.MultiPRS 0.134 0.143 -0.008 2.24e-01 0.140 0.150 -0.010 1.80e-02
IBD LDpred2.10FCVal LDpred2.MultiPRS 0.143 0.143 0.000 9.61e-01 0.149 0.150 -0.001 4.47e-01
IBD LDpred2.PseudoVal LDpred2.MultiPRS 0.140 0.143 -0.003 6.99e-01 0.145 0.150 -0.005 1.09e-02
IBD SBLUP.Inf LDpred2.MultiPRS 0.097 0.143 -0.045 1.02e-10 0.102 0.150 -0.048 2.15e-09
IBD LDpred2.MultiPRS LDpred2.10FCVal 0.143 0.143 0.000 9.61e-01 0.150 0.149 0.001 4.47e-01
IBD pT+clump.10FCVal LDpred2.10FCVal 0.111 0.143 -0.032 5.93e-18 0.109 0.149 -0.041 2.40e-08
IBD lassosum.PseudoVal LDpred2.10FCVal 0.133 0.143 -0.010 6.59e-06 0.140 0.149 -0.010 2.60e-02
IBD All.MultiPRS LDpred2.10FCVal 0.146 0.143 0.003 6.41e-01 0.152 0.149 0.003 2.76e-01
IBD LDpred1.MultiPRS LDpred2.10FCVal 0.130 0.143 -0.013 6.46e-02 0.138 0.149 -0.011 4.92e-03
IBD LDpred2.PseudoVal LDpred2.10FCVal 0.140 0.143 -0.003 2.01e-02 0.145 0.149 -0.004 1.35e-01
IBD DBSLMM.PseudoVal LDpred2.10FCVal 0.130 0.143 -0.013 3.34e-07 0.136 0.149 -0.013 9.22e-03
IBD LDpred1.Inf LDpred2.10FCVal 0.098 0.143 -0.045 7.19e-33 0.103 0.149 -0.046 6.70e-10
IBD LDpred2.Inf LDpred2.10FCVal 0.096 0.143 -0.047 6.30e-36 0.100 0.149 -0.049 6.16e-11
IBD lassosum.MultiPRS LDpred2.10FCVal 0.144 0.143 0.001 9.27e-01 0.148 0.149 -0.001 6.78e-01
IBD LDpred1.10FCVal LDpred2.10FCVal 0.129 0.143 -0.014 9.42e-11 0.137 0.149 -0.012 3.99e-03
IBD pT+clump.MultiPRS LDpred2.10FCVal 0.127 0.143 -0.016 2.64e-02 0.136 0.149 -0.013 1.25e-02
IBD SBayesR.PseudoVal LDpred2.10FCVal 0.128 0.143 -0.015 3.45e-11 0.143 0.149 -0.006 2.05e-01
IBD lassosum.10FCVal LDpred2.10FCVal 0.134 0.143 -0.009 2.90e-06 0.140 0.149 -0.009 2.12e-02
IBD LDpred2.10FCVal LDpred2.10FCVal 0.143 0.143 0.000 1.00e+00 0.149 0.149 0.000 1.00e+00
IBD SBLUP.Inf LDpred2.10FCVal 0.097 0.143 -0.046 4.63e-34 0.102 0.149 -0.047 3.33e-10
IBD LDpred2.MultiPRS LDpred2.PseudoVal 0.143 0.140 0.003 6.99e-01 0.150 0.145 0.005 1.09e-02
IBD lassosum.PseudoVal LDpred2.PseudoVal 0.133 0.140 -0.007 2.66e-04 0.140 0.145 -0.006 1.22e-01
IBD All.MultiPRS LDpred2.PseudoVal 0.146 0.140 0.006 3.67e-01 0.152 0.145 0.007 2.11e-02
IBD LDpred1.MultiPRS LDpred2.PseudoVal 0.130 0.140 -0.010 1.57e-01 0.138 0.145 -0.007 2.01e-01
IBD DBSLMM.PseudoVal LDpred2.PseudoVal 0.130 0.140 -0.010 2.82e-04 0.136 0.145 -0.010 8.69e-02
IBD LDpred1.Inf LDpred2.PseudoVal 0.098 0.140 -0.042 9.50e-20 0.103 0.145 -0.042 3.57e-06
IBD LDpred2.Inf LDpred2.PseudoVal 0.096 0.140 -0.044 3.83e-21 0.100 0.145 -0.045 1.12e-06
IBD lassosum.MultiPRS LDpred2.PseudoVal 0.144 0.140 0.004 5.98e-01 0.148 0.145 0.002 5.49e-01
IBD LDpred1.10FCVal LDpred2.PseudoVal 0.129 0.140 -0.011 4.25e-04 0.137 0.145 -0.008 1.69e-01
IBD pT+clump.MultiPRS LDpred2.PseudoVal 0.127 0.140 -0.012 7.40e-02 0.136 0.145 -0.009 1.08e-01
IBD SBayesR.PseudoVal LDpred2.PseudoVal 0.128 0.140 -0.012 1.01e-07 0.143 0.145 -0.002 6.60e-01
IBD pT+clump.10FCVal LDpred2.PseudoVal 0.111 0.140 -0.029 2.26e-18 0.109 0.145 -0.037 2.09e-08
IBD lassosum.10FCVal LDpred2.PseudoVal 0.134 0.140 -0.006 9.74e-03 0.140 0.145 -0.005 2.78e-01
IBD LDpred2.10FCVal LDpred2.PseudoVal 0.143 0.140 0.003 2.01e-02 0.149 0.145 0.004 1.35e-01
IBD LDpred2.PseudoVal LDpred2.PseudoVal 0.140 0.140 0.000 1.00e+00 0.145 0.145 0.000 1.00e+00
IBD SBLUP.Inf LDpred2.PseudoVal 0.097 0.140 -0.043 5.17e-20 0.102 0.145 -0.043 3.15e-06
IBD DBSLMM.PseudoVal LDpred2.Inf 0.130 0.096 0.034 1.38e-14 0.136 0.100 0.036 4.87e-05
IBD LDpred2.MultiPRS LDpred2.Inf 0.143 0.096 0.047 3.28e-11 0.150 0.100 0.050 4.79e-10
IBD pT+clump.10FCVal LDpred2.Inf 0.111 0.096 0.015 8.14e-03 0.109 0.100 0.008 4.56e-01
IBD lassosum.10FCVal LDpred2.Inf 0.134 0.096 0.038 5.63e-19 0.140 0.100 0.040 2.32e-06
IBD lassosum.PseudoVal LDpred2.Inf 0.133 0.096 0.037 3.13e-13 0.140 0.100 0.039 9.86e-05
IBD All.MultiPRS LDpred2.Inf 0.146 0.096 0.050 8.73e-13 0.152 0.100 0.052 8.29e-11
IBD LDpred1.MultiPRS LDpred2.Inf 0.130 0.096 0.034 1.29e-06 0.138 0.100 0.038 1.94e-10
IBD LDpred2.PseudoVal LDpred2.Inf 0.140 0.096 0.044 3.83e-21 0.145 0.100 0.045 1.12e-06
IBD SBLUP.Inf LDpred2.Inf 0.097 0.096 0.001 1.23e-02 0.102 0.100 0.002 5.05e-02
IBD LDpred1.Inf LDpred2.Inf 0.098 0.096 0.002 1.40e-01 0.103 0.100 0.003 3.79e-01
IBD LDpred2.Inf LDpred2.Inf 0.096 0.096 0.000 1.00e+00 0.100 0.100 0.000 1.00e+00
IBD lassosum.MultiPRS LDpred2.Inf 0.144 0.096 0.048 1.18e-11 0.148 0.100 0.048 2.35e-09
IBD LDpred1.10FCVal LDpred2.Inf 0.129 0.096 0.033 1.12e-34 0.137 0.100 0.037 6.92e-12
IBD pT+clump.MultiPRS LDpred2.Inf 0.127 0.096 0.031 7.12e-06 0.136 0.100 0.036 2.73e-05
IBD SBayesR.PseudoVal LDpred2.Inf 0.128 0.096 0.032 1.95e-12 0.143 0.100 0.043 1.71e-06
IBD LDpred2.10FCVal LDpred2.Inf 0.143 0.096 0.047 6.30e-36 0.149 0.100 0.049 6.16e-11
IBD All.MultiPRS pT+clump.MultiPRS 0.146 0.127 0.019 7.14e-03 0.152 0.136 0.016 9.79e-04
IBD LDpred1.MultiPRS pT+clump.MultiPRS 0.130 0.127 0.003 7.08e-01 0.138 0.136 0.002 7.07e-01
IBD LDpred2.PseudoVal pT+clump.MultiPRS 0.140 0.127 0.012 7.40e-02 0.145 0.136 0.009 1.08e-01
IBD DBSLMM.PseudoVal pT+clump.MultiPRS 0.130 0.127 0.002 7.41e-01 0.136 0.136 0.000 9.70e-01
IBD LDpred1.Inf pT+clump.MultiPRS 0.098 0.127 -0.029 3.14e-05 0.103 0.136 -0.033 5.55e-05
IBD LDpred2.Inf pT+clump.MultiPRS 0.096 0.127 -0.031 7.12e-06 0.100 0.136 -0.036 2.73e-05
IBD lassosum.MultiPRS pT+clump.MultiPRS 0.144 0.127 0.016 2.06e-02 0.148 0.136 0.012 2.19e-02
IBD LDpred1.10FCVal pT+clump.MultiPRS 0.129 0.127 0.002 8.08e-01 0.137 0.136 0.001 8.72e-01
IBD lassosum.PseudoVal pT+clump.MultiPRS 0.133 0.127 0.006 4.17e-01 0.140 0.136 0.004 5.45e-01
IBD LDpred2.MultiPRS pT+clump.MultiPRS 0.143 0.127 0.015 2.96e-02 0.150 0.136 0.014 6.14e-03
IBD pT+clump.10FCVal pT+clump.MultiPRS 0.111 0.127 -0.017 1.84e-02 0.109 0.136 -0.027 1.36e-07
IBD lassosum.10FCVal pT+clump.MultiPRS 0.134 0.127 0.007 3.39e-01 0.140 0.136 0.004 4.32e-01
IBD LDpred2.10FCVal pT+clump.MultiPRS 0.143 0.127 0.016 2.64e-02 0.149 0.136 0.013 1.25e-02
IBD SBayesR.PseudoVal pT+clump.MultiPRS 0.128 0.127 0.000 9.86e-01 0.143 0.136 0.007 2.52e-01
IBD SBLUP.Inf pT+clump.MultiPRS 0.097 0.127 -0.030 1.57e-05 0.102 0.136 -0.034 6.41e-05
IBD pT+clump.MultiPRS pT+clump.MultiPRS 0.127 0.127 0.000 1.00e+00 0.136 0.136 0.000 1.00e+00
IBD lassosum.PseudoVal pT+clump.10FCVal 0.133 0.111 0.022 2.09e-11 0.140 0.109 0.031 2.25e-06
IBD All.MultiPRS pT+clump.10FCVal 0.146 0.111 0.035 4.48e-07 0.152 0.109 0.043 1.80e-10
IBD DBSLMM.PseudoVal pT+clump.10FCVal 0.130 0.111 0.019 2.68e-07 0.136 0.109 0.027 1.73e-04
IBD LDpred1.Inf pT+clump.10FCVal 0.098 0.111 -0.013 1.99e-02 0.103 0.109 -0.006 6.03e-01
IBD LDpred2.Inf pT+clump.10FCVal 0.096 0.111 -0.015 8.14e-03 0.100 0.109 -0.008 4.56e-01
IBD lassosum.MultiPRS pT+clump.10FCVal 0.144 0.111 0.033 2.95e-06 0.148 0.109 0.039 5.45e-08
IBD LDpred1.10FCVal pT+clump.10FCVal 0.129 0.111 0.018 3.40e-05 0.137 0.109 0.028 1.04e-03
IBD pT+clump.MultiPRS pT+clump.10FCVal 0.127 0.111 0.017 1.84e-02 0.136 0.109 0.027 1.36e-07
IBD LDpred2.MultiPRS pT+clump.10FCVal 0.143 0.111 0.032 5.89e-06 0.150 0.109 0.042 1.01e-09
IBD pT+clump.10FCVal pT+clump.10FCVal 0.111 0.111 0.000 1.00e+00 0.109 0.109 0.000 1.00e+00
IBD lassosum.10FCVal pT+clump.10FCVal 0.134 0.111 0.023 6.20e-09 0.140 0.109 0.032 5.42e-05
IBD LDpred2.10FCVal pT+clump.10FCVal 0.143 0.111 0.032 5.93e-18 0.149 0.109 0.041 2.40e-08
IBD SBayesR.PseudoVal pT+clump.10FCVal 0.128 0.111 0.017 8.70e-06 0.143 0.109 0.035 2.07e-06
IBD LDpred1.MultiPRS pT+clump.10FCVal 0.130 0.111 0.019 6.27e-03 0.138 0.109 0.030 3.59e-04
IBD LDpred2.PseudoVal pT+clump.10FCVal 0.140 0.111 0.029 2.26e-18 0.145 0.109 0.037 2.09e-08
IBD SBLUP.Inf pT+clump.10FCVal 0.097 0.111 -0.014 1.54e-02 0.102 0.109 -0.006 5.65e-01
IBD LDpred1.Inf SBayesR.PseudoVal 0.098 0.128 -0.029 6.35e-12 0.103 0.143 -0.040 2.28e-06
IBD DBSLMM.PseudoVal SBayesR.PseudoVal 0.130 0.128 0.002 4.59e-01 0.136 0.143 -0.008 2.05e-01
IBD lassosum.PseudoVal SBayesR.PseudoVal 0.133 0.128 0.006 3.33e-02 0.140 0.143 -0.004 4.66e-01
IBD LDpred2.MultiPRS SBayesR.PseudoVal 0.143 0.128 0.015 3.12e-02 0.150 0.143 0.007 9.69e-02
IBD pT+clump.10FCVal SBayesR.PseudoVal 0.111 0.128 -0.017 8.70e-06 0.109 0.143 -0.035 2.07e-06
IBD lassosum.10FCVal SBayesR.PseudoVal 0.134 0.128 0.007 2.11e-02 0.140 0.143 -0.003 6.16e-01
IBD LDpred2.10FCVal SBayesR.PseudoVal 0.143 0.128 0.015 3.45e-11 0.149 0.143 0.006 2.05e-01
IBD All.MultiPRS SBayesR.PseudoVal 0.146 0.128 0.019 7.54e-03 0.152 0.143 0.009 6.34e-02
IBD LDpred1.MultiPRS SBayesR.PseudoVal 0.130 0.128 0.002 7.21e-01 0.138 0.143 -0.005 3.38e-01
IBD LDpred2.PseudoVal SBayesR.PseudoVal 0.140 0.128 0.012 1.01e-07 0.145 0.143 0.002 6.60e-01
IBD SBLUP.Inf SBayesR.PseudoVal 0.097 0.128 -0.030 1.54e-11 0.102 0.143 -0.041 4.96e-06
IBD pT+clump.MultiPRS SBayesR.PseudoVal 0.127 0.128 0.000 9.86e-01 0.136 0.143 -0.007 2.52e-01
IBD LDpred2.Inf SBayesR.PseudoVal 0.096 0.128 -0.032 1.95e-12 0.100 0.143 -0.043 1.71e-06
IBD lassosum.MultiPRS SBayesR.PseudoVal 0.144 0.128 0.016 2.15e-02 0.148 0.143 0.004 3.78e-01
IBD LDpred1.10FCVal SBayesR.PseudoVal 0.129 0.128 0.002 5.75e-01 0.137 0.143 -0.006 2.63e-01
IBD SBayesR.PseudoVal SBayesR.PseudoVal 0.128 0.128 0.000 1.00e+00 0.143 0.143 0.000 1.00e+00
IBD All.MultiPRS SBLUP.Inf 0.146 0.097 0.049 2.97e-12 0.152 0.102 0.050 2.75e-10
IBD LDpred1.Inf SBLUP.Inf 0.098 0.097 0.001 4.92e-01 0.103 0.102 0.001 7.84e-01
IBD LDpred2.Inf SBLUP.Inf 0.096 0.097 -0.001 1.23e-02 0.100 0.102 -0.002 5.05e-02
IBD DBSLMM.PseudoVal SBLUP.Inf 0.130 0.097 0.033 1.41e-13 0.136 0.102 0.034 1.24e-04
IBD lassosum.PseudoVal SBLUP.Inf 0.133 0.097 0.036 1.77e-12 0.140 0.102 0.037 2.07e-04
IBD LDpred2.MultiPRS SBLUP.Inf 0.143 0.097 0.045 1.02e-10 0.150 0.102 0.048 2.15e-09
IBD pT+clump.10FCVal SBLUP.Inf 0.111 0.097 0.014 1.54e-02 0.109 0.102 0.006 5.65e-01
IBD lassosum.10FCVal SBLUP.Inf 0.134 0.097 0.037 4.93e-18 0.140 0.102 0.038 6.02e-06
IBD LDpred2.10FCVal SBLUP.Inf 0.143 0.097 0.046 4.63e-34 0.149 0.102 0.047 3.33e-10
IBD SBayesR.PseudoVal SBLUP.Inf 0.128 0.097 0.030 1.54e-11 0.143 0.102 0.041 4.96e-06
IBD LDpred1.MultiPRS SBLUP.Inf 0.130 0.097 0.033 2.98e-06 0.138 0.102 0.036 1.27e-09
IBD LDpred2.PseudoVal SBLUP.Inf 0.140 0.097 0.043 5.17e-20 0.145 0.102 0.043 3.15e-06
IBD SBLUP.Inf SBLUP.Inf 0.097 0.097 0.000 1.00e+00 0.102 0.102 0.000 1.00e+00
IBD pT+clump.MultiPRS SBLUP.Inf 0.127 0.097 0.030 1.57e-05 0.136 0.102 0.034 6.41e-05
IBD lassosum.MultiPRS SBLUP.Inf 0.144 0.097 0.046 3.76e-11 0.148 0.102 0.046 6.21e-09
IBD LDpred1.10FCVal SBLUP.Inf 0.129 0.097 0.032 2.01e-32 0.137 0.102 0.035 6.36e-11
MultiScler lassosum.PseudoVal All.MultiPRS 0.103 0.135 -0.032 5.21e-06 0.102 0.121 -0.019 5.54e-03
MultiScler All.MultiPRS All.MultiPRS 0.135 0.135 0.000 1.00e+00 0.121 0.121 0.000 1.00e+00
MultiScler DBSLMM.PseudoVal All.MultiPRS 0.091 0.135 -0.044 3.53e-10 0.088 0.121 -0.033 6.81e-05
MultiScler LDpred1.Inf All.MultiPRS 0.090 0.135 -0.046 6.81e-11 0.078 0.121 -0.042 4.17e-07
MultiScler LDpred2.Inf All.MultiPRS 0.094 0.135 -0.041 3.76e-09 0.076 0.121 -0.044 5.44e-07
MultiScler lassosum.MultiPRS All.MultiPRS 0.128 0.135 -0.008 1.56e-04 0.119 0.121 -0.002 5.77e-01
MultiScler LDpred1.10FCVal All.MultiPRS 0.107 0.135 -0.028 6.59e-05 0.096 0.121 -0.025 1.08e-04
MultiScler pT+clump.MultiPRS All.MultiPRS 0.114 0.135 -0.021 2.61e-03 0.108 0.121 -0.012 2.32e-02
MultiScler LDpred2.MultiPRS All.MultiPRS 0.133 0.135 -0.003 1.33e-03 0.119 0.121 -0.002 2.87e-01
MultiScler pT+clump.10FCVal All.MultiPRS 0.090 0.135 -0.045 1.18e-10 0.092 0.121 -0.029 4.11e-04
MultiScler lassosum.10FCVal All.MultiPRS 0.115 0.135 -0.020 4.13e-03 0.097 0.121 -0.024 1.42e-04
MultiScler LDpred2.10FCVal All.MultiPRS 0.120 0.135 -0.015 3.18e-02 0.108 0.121 -0.013 3.84e-03
MultiScler SBayesR.PseudoVal All.MultiPRS 0.102 0.135 -0.034 1.27e-06 0.083 0.121 -0.038 5.56e-07
MultiScler LDpred1.MultiPRS All.MultiPRS 0.112 0.135 -0.023 1.42e-13 0.096 0.121 -0.025 4.26e-05
MultiScler LDpred2.PseudoVal All.MultiPRS 0.119 0.135 -0.017 1.74e-02 0.110 0.121 -0.010 1.28e-02
MultiScler SBLUP.Inf All.MultiPRS 0.094 0.135 -0.042 3.21e-09 0.076 0.121 -0.045 3.67e-07
MultiScler LDpred2.MultiPRS DBSLMM.PseudoVal 0.133 0.091 0.041 3.65e-09 0.119 0.088 0.031 7.58e-05
MultiScler pT+clump.10FCVal DBSLMM.PseudoVal 0.090 0.091 -0.001 7.36e-01 0.092 0.088 0.004 5.67e-01
MultiScler lassosum.PseudoVal DBSLMM.PseudoVal 0.103 0.091 0.012 2.28e-07 0.102 0.088 0.014 3.17e-03
MultiScler All.MultiPRS DBSLMM.PseudoVal 0.135 0.091 0.044 3.53e-10 0.121 0.088 0.033 6.81e-05
MultiScler LDpred1.MultiPRS DBSLMM.PseudoVal 0.112 0.091 0.021 2.85e-03 0.096 0.088 0.008 3.09e-01
MultiScler LDpred2.PseudoVal DBSLMM.PseudoVal 0.119 0.091 0.027 2.92e-11 0.110 0.088 0.022 7.23e-03
MultiScler DBSLMM.PseudoVal DBSLMM.PseudoVal 0.091 0.091 0.000 1.00e+00 0.088 0.088 0.000 1.00e+00
MultiScler LDpred1.Inf DBSLMM.PseudoVal 0.090 0.091 -0.002 7.30e-01 0.078 0.088 -0.010 3.60e-01
MultiScler LDpred2.Inf DBSLMM.PseudoVal 0.094 0.091 0.003 6.74e-01 0.076 0.088 -0.012 3.57e-01
MultiScler lassosum.MultiPRS DBSLMM.PseudoVal 0.128 0.091 0.036 2.09e-07 0.119 0.088 0.030 6.93e-05
MultiScler LDpred1.10FCVal DBSLMM.PseudoVal 0.107 0.091 0.016 1.47e-05 0.096 0.088 0.007 3.11e-01
MultiScler pT+clump.MultiPRS DBSLMM.PseudoVal 0.114 0.091 0.023 1.01e-03 0.108 0.088 0.020 1.81e-02
MultiScler SBayesR.PseudoVal DBSLMM.PseudoVal 0.102 0.091 0.010 1.02e-01 0.083 0.088 -0.005 6.88e-01
MultiScler lassosum.10FCVal DBSLMM.PseudoVal 0.115 0.091 0.024 7.66e-07 0.097 0.088 0.009 3.77e-01
MultiScler LDpred2.10FCVal DBSLMM.PseudoVal 0.120 0.091 0.029 5.00e-27 0.108 0.088 0.020 3.35e-04
MultiScler SBLUP.Inf DBSLMM.PseudoVal 0.094 0.091 0.002 6.96e-01 0.076 0.088 -0.012 3.28e-01
MultiScler All.MultiPRS lassosum.MultiPRS 0.135 0.128 0.008 1.56e-04 0.121 0.119 0.002 5.77e-01
MultiScler LDpred1.MultiPRS lassosum.MultiPRS 0.112 0.128 -0.015 1.86e-07 0.096 0.119 -0.023 1.10e-04
MultiScler LDpred1.Inf lassosum.MultiPRS 0.090 0.128 -0.038 5.29e-08 0.078 0.119 -0.040 1.39e-07
MultiScler LDpred2.Inf lassosum.MultiPRS 0.094 0.128 -0.034 1.56e-06 0.076 0.119 -0.042 2.91e-07
MultiScler lassosum.MultiPRS lassosum.MultiPRS 0.128 0.128 0.000 1.00e+00 0.119 0.119 0.000 1.00e+00
MultiScler DBSLMM.PseudoVal lassosum.MultiPRS 0.091 0.128 -0.036 2.09e-07 0.088 0.119 -0.030 6.93e-05
MultiScler lassosum.PseudoVal lassosum.MultiPRS 0.103 0.128 -0.024 5.13e-04 0.102 0.119 -0.016 1.39e-03
MultiScler LDpred2.MultiPRS lassosum.MultiPRS 0.133 0.128 0.005 1.98e-02 0.119 0.119 0.001 9.05e-01
MultiScler pT+clump.10FCVal lassosum.MultiPRS 0.090 0.128 -0.038 8.61e-08 0.092 0.119 -0.027 3.25e-03
MultiScler lassosum.10FCVal lassosum.MultiPRS 0.115 0.128 -0.012 7.49e-02 0.097 0.119 -0.022 1.66e-06
MultiScler LDpred2.10FCVal lassosum.MultiPRS 0.120 0.128 -0.007 2.89e-01 0.108 0.119 -0.011 5.45e-02
MultiScler SBayesR.PseudoVal lassosum.MultiPRS 0.102 0.128 -0.026 1.75e-04 0.083 0.119 -0.036 2.18e-05
MultiScler LDpred2.PseudoVal lassosum.MultiPRS 0.119 0.128 -0.009 1.97e-01 0.110 0.119 -0.008 1.48e-01
MultiScler SBLUP.Inf lassosum.MultiPRS 0.094 0.128 -0.034 1.36e-06 0.076 0.119 -0.043 1.85e-07
MultiScler pT+clump.MultiPRS lassosum.MultiPRS 0.114 0.128 -0.013 5.50e-02 0.108 0.119 -0.010 7.50e-02
MultiScler LDpred1.10FCVal lassosum.MultiPRS 0.107 0.128 -0.020 3.65e-03 0.096 0.119 -0.023 5.29e-05
MultiScler All.MultiPRS lassosum.PseudoVal 0.135 0.103 0.032 5.21e-06 0.121 0.102 0.019 5.54e-03
MultiScler LDpred1.MultiPRS lassosum.PseudoVal 0.112 0.103 0.009 2.06e-01 0.096 0.102 -0.007 3.04e-01
MultiScler LDpred2.PseudoVal lassosum.PseudoVal 0.119 0.103 0.015 1.16e-06 0.110 0.102 0.008 1.84e-01
MultiScler DBSLMM.PseudoVal lassosum.PseudoVal 0.091 0.103 -0.012 2.28e-07 0.088 0.102 -0.014 3.17e-03
MultiScler LDpred1.Inf lassosum.PseudoVal 0.090 0.103 -0.014 3.81e-03 0.078 0.102 -0.024 1.32e-02
MultiScler LDpred2.Inf lassosum.PseudoVal 0.094 0.103 -0.009 9.86e-02 0.076 0.102 -0.026 2.48e-02
MultiScler lassosum.MultiPRS lassosum.PseudoVal 0.128 0.103 0.024 5.13e-04 0.119 0.102 0.016 1.39e-03
MultiScler LDpred1.10FCVal lassosum.PseudoVal 0.107 0.103 0.004 2.18e-01 0.096 0.102 -0.007 2.89e-01
MultiScler lassosum.PseudoVal lassosum.PseudoVal 0.103 0.103 0.000 1.00e+00 0.102 0.102 0.000 1.00e+00
MultiScler LDpred2.MultiPRS lassosum.PseudoVal 0.133 0.103 0.029 2.89e-05 0.119 0.102 0.017 9.00e-03
MultiScler pT+clump.10FCVal lassosum.PseudoVal 0.090 0.103 -0.013 1.21e-03 0.092 0.102 -0.010 2.21e-01
MultiScler lassosum.10FCVal lassosum.PseudoVal 0.115 0.103 0.012 2.06e-03 0.097 0.102 -0.006 4.57e-01
MultiScler LDpred2.10FCVal lassosum.PseudoVal 0.120 0.103 0.017 1.14e-13 0.108 0.102 0.006 2.21e-01
MultiScler SBayesR.PseudoVal lassosum.PseudoVal 0.102 0.103 -0.002 7.30e-01 0.083 0.102 -0.019 8.51e-02
MultiScler SBLUP.Inf lassosum.PseudoVal 0.094 0.103 -0.010 9.21e-02 0.076 0.102 -0.027 2.11e-02
MultiScler pT+clump.MultiPRS lassosum.PseudoVal 0.114 0.103 0.011 1.20e-01 0.108 0.102 0.006 4.28e-01
MultiScler All.MultiPRS lassosum.10FCVal 0.135 0.115 0.020 4.13e-03 0.121 0.097 0.024 1.42e-04
MultiScler LDpred1.MultiPRS lassosum.10FCVal 0.112 0.115 -0.003 6.77e-01 0.096 0.097 -0.001 9.00e-01
MultiScler LDpred1.Inf lassosum.10FCVal 0.090 0.115 -0.026 1.60e-12 0.078 0.097 -0.018 1.38e-02
MultiScler LDpred2.Inf lassosum.10FCVal 0.094 0.115 -0.021 1.49e-09 0.076 0.097 -0.020 4.82e-03
MultiScler lassosum.MultiPRS lassosum.10FCVal 0.128 0.115 0.012 7.49e-02 0.119 0.097 0.022 1.66e-06
MultiScler DBSLMM.PseudoVal lassosum.10FCVal 0.091 0.115 -0.024 7.66e-07 0.088 0.097 -0.009 3.77e-01
MultiScler lassosum.PseudoVal lassosum.10FCVal 0.103 0.115 -0.012 2.06e-03 0.102 0.097 0.006 4.57e-01
MultiScler LDpred2.MultiPRS lassosum.10FCVal 0.133 0.115 0.017 1.27e-02 0.119 0.097 0.022 7.35e-04
MultiScler pT+clump.10FCVal lassosum.10FCVal 0.090 0.115 -0.025 3.52e-06 0.092 0.097 -0.005 6.70e-01
MultiScler lassosum.10FCVal lassosum.10FCVal 0.115 0.115 0.000 1.00e+00 0.097 0.097 0.000 1.00e+00
MultiScler LDpred2.10FCVal lassosum.10FCVal 0.120 0.115 0.005 2.28e-01 0.108 0.097 0.011 1.76e-01
MultiScler SBayesR.PseudoVal lassosum.10FCVal 0.102 0.115 -0.014 1.99e-03 0.083 0.097 -0.014 1.26e-01
MultiScler LDpred2.PseudoVal lassosum.10FCVal 0.119 0.115 0.003 3.86e-01 0.110 0.097 0.014 8.02e-02
MultiScler SBLUP.Inf lassosum.10FCVal 0.094 0.115 -0.021 1.23e-09 0.076 0.097 -0.021 3.62e-03
MultiScler pT+clump.MultiPRS lassosum.10FCVal 0.114 0.115 -0.001 8.94e-01 0.108 0.097 0.012 9.64e-02
MultiScler LDpred1.10FCVal lassosum.10FCVal 0.107 0.115 -0.008 1.87e-02 0.096 0.097 -0.001 8.78e-01
MultiScler DBSLMM.PseudoVal LDpred1.MultiPRS 0.091 0.112 -0.021 2.85e-03 0.088 0.096 -0.008 3.09e-01
MultiScler LDpred2.MultiPRS LDpred1.MultiPRS 0.133 0.112 0.020 9.21e-11 0.119 0.096 0.023 1.53e-04
MultiScler pT+clump.10FCVal LDpred1.MultiPRS 0.090 0.112 -0.022 1.66e-03 0.092 0.096 -0.004 6.97e-01
MultiScler lassosum.10FCVal LDpred1.MultiPRS 0.115 0.112 0.003 6.77e-01 0.097 0.096 0.001 9.00e-01
MultiScler lassosum.PseudoVal LDpred1.MultiPRS 0.103 0.112 -0.009 2.06e-01 0.102 0.096 0.007 3.04e-01
MultiScler All.MultiPRS LDpred1.MultiPRS 0.135 0.112 0.023 1.42e-13 0.121 0.096 0.025 4.26e-05
MultiScler LDpred1.MultiPRS LDpred1.MultiPRS 0.112 0.112 0.000 1.00e+00 0.096 0.096 0.000 1.00e+00
MultiScler LDpred2.PseudoVal LDpred1.MultiPRS 0.119 0.112 0.006 3.60e-01 0.110 0.096 0.015 4.73e-02
MultiScler SBLUP.Inf LDpred1.MultiPRS 0.094 0.112 -0.019 8.26e-03 0.076 0.096 -0.020 3.61e-02
MultiScler LDpred1.Inf LDpred1.MultiPRS 0.090 0.112 -0.023 1.18e-03 0.078 0.096 -0.017 3.87e-03
MultiScler LDpred2.Inf LDpred1.MultiPRS 0.094 0.112 -0.018 8.94e-03 0.076 0.096 -0.019 4.31e-02
MultiScler lassosum.MultiPRS LDpred1.MultiPRS 0.128 0.112 0.015 1.86e-07 0.119 0.096 0.023 1.10e-04
MultiScler LDpred1.10FCVal LDpred1.MultiPRS 0.107 0.112 -0.005 4.78e-01 0.096 0.096 0.000 9.63e-01
MultiScler pT+clump.MultiPRS LDpred1.MultiPRS 0.114 0.112 0.002 7.76e-01 0.108 0.096 0.013 1.14e-01
MultiScler SBayesR.PseudoVal LDpred1.MultiPRS 0.102 0.112 -0.011 1.23e-01 0.083 0.096 -0.013 2.15e-01
MultiScler LDpred2.10FCVal LDpred1.MultiPRS 0.120 0.112 0.008 2.55e-01 0.108 0.096 0.012 6.07e-02
MultiScler All.MultiPRS LDpred1.Inf 0.135 0.090 0.046 6.81e-11 0.121 0.078 0.042 4.17e-07
MultiScler LDpred1.Inf LDpred1.Inf 0.090 0.090 0.000 1.00e+00 0.078 0.078 0.000 1.00e+00
MultiScler LDpred2.Inf LDpred1.Inf 0.094 0.090 0.004 2.06e-01 0.076 0.078 -0.002 7.82e-01
MultiScler DBSLMM.PseudoVal LDpred1.Inf 0.091 0.090 0.002 7.30e-01 0.088 0.078 0.010 3.60e-01
MultiScler lassosum.PseudoVal LDpred1.Inf 0.103 0.090 0.014 3.81e-03 0.102 0.078 0.024 1.32e-02
MultiScler LDpred2.MultiPRS LDpred1.Inf 0.133 0.090 0.043 7.69e-10 0.119 0.078 0.041 9.66e-07
MultiScler pT+clump.10FCVal LDpred1.Inf 0.090 0.090 0.001 9.04e-01 0.092 0.078 0.014 2.52e-01
MultiScler lassosum.10FCVal LDpred1.Inf 0.115 0.090 0.026 1.60e-12 0.097 0.078 0.018 1.38e-02
MultiScler LDpred2.10FCVal LDpred1.Inf 0.120 0.090 0.031 3.46e-10 0.108 0.078 0.029 2.69e-03
MultiScler SBayesR.PseudoVal LDpred1.Inf 0.102 0.090 0.012 1.20e-02 0.083 0.078 0.005 6.27e-01
MultiScler LDpred1.MultiPRS LDpred1.Inf 0.112 0.090 0.023 1.18e-03 0.096 0.078 0.017 3.87e-03
MultiScler LDpred2.PseudoVal LDpred1.Inf 0.119 0.090 0.029 4.03e-09 0.110 0.078 0.032 1.18e-03
MultiScler SBLUP.Inf LDpred1.Inf 0.094 0.090 0.004 2.27e-01 0.076 0.078 -0.003 7.06e-01
MultiScler pT+clump.MultiPRS LDpred1.Inf 0.114 0.090 0.025 3.91e-04 0.108 0.078 0.030 1.29e-03
MultiScler lassosum.MultiPRS LDpred1.Inf 0.128 0.090 0.038 5.29e-08 0.119 0.078 0.040 1.39e-07
MultiScler LDpred1.10FCVal LDpred1.Inf 0.107 0.090 0.018 2.12e-13 0.096 0.078 0.017 4.69e-04
MultiScler LDpred1.Inf LDpred1.10FCVal 0.090 0.107 -0.018 2.12e-13 0.078 0.096 -0.017 4.69e-04
MultiScler DBSLMM.PseudoVal LDpred1.10FCVal 0.091 0.107 -0.016 1.47e-05 0.088 0.096 -0.007 3.11e-01
MultiScler lassosum.PseudoVal LDpred1.10FCVal 0.103 0.107 -0.004 2.18e-01 0.102 0.096 0.007 2.89e-01
MultiScler LDpred2.MultiPRS LDpred1.10FCVal 0.133 0.107 0.025 2.98e-04 0.119 0.096 0.023 1.82e-04
MultiScler pT+clump.10FCVal LDpred1.10FCVal 0.090 0.107 -0.017 3.98e-04 0.092 0.096 -0.004 7.13e-01
MultiScler lassosum.10FCVal LDpred1.10FCVal 0.115 0.107 0.008 1.87e-02 0.097 0.096 0.001 8.78e-01
MultiScler LDpred2.10FCVal LDpred1.10FCVal 0.120 0.107 0.013 1.08e-04 0.108 0.096 0.012 6.61e-02
MultiScler All.MultiPRS LDpred1.10FCVal 0.135 0.107 0.028 6.59e-05 0.121 0.096 0.025 1.08e-04
MultiScler LDpred1.MultiPRS LDpred1.10FCVal 0.112 0.107 0.005 4.78e-01 0.096 0.096 0.000 9.63e-01
MultiScler LDpred2.PseudoVal LDpred1.10FCVal 0.119 0.107 0.011 3.90e-03 0.110 0.096 0.015 5.69e-02
MultiScler SBLUP.Inf LDpred1.10FCVal 0.094 0.107 -0.014 2.86e-03 0.076 0.096 -0.020 3.01e-02
MultiScler pT+clump.MultiPRS LDpred1.10FCVal 0.114 0.107 0.007 3.18e-01 0.108 0.096 0.013 1.13e-01
MultiScler LDpred2.Inf LDpred1.10FCVal 0.094 0.107 -0.013 3.24e-03 0.076 0.096 -0.019 3.63e-02
MultiScler lassosum.MultiPRS LDpred1.10FCVal 0.128 0.107 0.020 3.65e-03 0.119 0.096 0.023 5.29e-05
MultiScler LDpred1.10FCVal LDpred1.10FCVal 0.107 0.107 0.000 1.00e+00 0.096 0.096 0.000 1.00e+00
MultiScler SBayesR.PseudoVal LDpred1.10FCVal 0.102 0.107 -0.006 2.61e-01 0.083 0.096 -0.013 2.26e-01
MultiScler LDpred2.MultiPRS LDpred2.MultiPRS 0.133 0.133 0.000 1.00e+00 0.119 0.119 0.000 1.00e+00
MultiScler lassosum.PseudoVal LDpred2.MultiPRS 0.103 0.133 -0.029 2.89e-05 0.102 0.119 -0.017 9.00e-03
MultiScler All.MultiPRS LDpred2.MultiPRS 0.135 0.133 0.003 1.33e-03 0.121 0.119 0.002 2.87e-01
MultiScler LDpred1.MultiPRS LDpred2.MultiPRS 0.112 0.133 -0.020 9.21e-11 0.096 0.119 -0.023 1.53e-04
MultiScler DBSLMM.PseudoVal LDpred2.MultiPRS 0.091 0.133 -0.041 3.65e-09 0.088 0.119 -0.031 7.58e-05
MultiScler LDpred1.Inf LDpred2.MultiPRS 0.090 0.133 -0.043 7.69e-10 0.078 0.119 -0.041 9.66e-07
MultiScler LDpred2.Inf LDpred2.MultiPRS 0.094 0.133 -0.039 3.35e-08 0.076 0.119 -0.043 1.12e-06
MultiScler lassosum.MultiPRS LDpred2.MultiPRS 0.128 0.133 -0.005 1.98e-02 0.119 0.119 -0.001 9.05e-01
MultiScler LDpred1.10FCVal LDpred2.MultiPRS 0.107 0.133 -0.025 2.98e-04 0.096 0.119 -0.023 1.82e-04
MultiScler pT+clump.MultiPRS LDpred2.MultiPRS 0.114 0.133 -0.018 8.43e-03 0.108 0.119 -0.011 6.66e-02
MultiScler SBayesR.PseudoVal LDpred2.MultiPRS 0.102 0.133 -0.031 7.85e-06 0.083 0.119 -0.036 9.10e-06
MultiScler pT+clump.10FCVal LDpred2.MultiPRS 0.090 0.133 -0.042 1.33e-09 0.092 0.119 -0.027 8.30e-04
MultiScler lassosum.10FCVal LDpred2.MultiPRS 0.115 0.133 -0.017 1.27e-02 0.097 0.119 -0.022 7.35e-04
MultiScler LDpred2.10FCVal LDpred2.MultiPRS 0.120 0.133 -0.012 7.64e-02 0.108 0.119 -0.011 5.46e-03
MultiScler LDpred2.PseudoVal LDpred2.MultiPRS 0.119 0.133 -0.014 4.53e-02 0.110 0.119 -0.009 3.50e-02
MultiScler SBLUP.Inf LDpred2.MultiPRS 0.094 0.133 -0.039 2.88e-08 0.076 0.119 -0.043 7.51e-07
MultiScler LDpred2.MultiPRS LDpred2.10FCVal 0.133 0.120 0.012 7.64e-02 0.119 0.108 0.011 5.46e-03
MultiScler pT+clump.10FCVal LDpred2.10FCVal 0.090 0.120 -0.030 2.31e-19 0.092 0.108 -0.016 2.38e-02
MultiScler lassosum.PseudoVal LDpred2.10FCVal 0.103 0.120 -0.017 1.14e-13 0.102 0.108 -0.006 2.21e-01
MultiScler All.MultiPRS LDpred2.10FCVal 0.135 0.120 0.015 3.18e-02 0.121 0.108 0.013 3.84e-03
MultiScler LDpred1.MultiPRS LDpred2.10FCVal 0.112 0.120 -0.008 2.55e-01 0.096 0.108 -0.012 6.07e-02
MultiScler LDpred2.PseudoVal LDpred2.10FCVal 0.119 0.120 -0.002 4.87e-01 0.110 0.108 0.003 5.47e-01
MultiScler DBSLMM.PseudoVal LDpred2.10FCVal 0.091 0.120 -0.029 5.00e-27 0.088 0.108 -0.020 3.35e-04
MultiScler LDpred1.Inf LDpred2.10FCVal 0.090 0.120 -0.031 3.46e-10 0.078 0.108 -0.029 2.69e-03
MultiScler LDpred2.Inf LDpred2.10FCVal 0.094 0.120 -0.026 3.16e-06 0.076 0.108 -0.031 5.76e-03
MultiScler lassosum.MultiPRS LDpred2.10FCVal 0.128 0.120 0.007 2.89e-01 0.119 0.108 0.011 5.45e-02
MultiScler LDpred1.10FCVal LDpred2.10FCVal 0.107 0.120 -0.013 1.08e-04 0.096 0.108 -0.012 6.61e-02
MultiScler pT+clump.MultiPRS LDpred2.10FCVal 0.114 0.120 -0.006 3.90e-01 0.108 0.108 0.001 9.32e-01
MultiScler SBayesR.PseudoVal LDpred2.10FCVal 0.102 0.120 -0.019 2.03e-04 0.083 0.108 -0.025 1.49e-02
MultiScler lassosum.10FCVal LDpred2.10FCVal 0.115 0.120 -0.005 2.28e-01 0.097 0.108 -0.011 1.76e-01
MultiScler LDpred2.10FCVal LDpred2.10FCVal 0.120 0.120 0.000 1.00e+00 0.108 0.108 0.000 1.00e+00
MultiScler SBLUP.Inf LDpred2.10FCVal 0.094 0.120 -0.027 2.71e-06 0.076 0.108 -0.032 4.75e-03
MultiScler LDpred2.MultiPRS LDpred2.PseudoVal 0.133 0.119 0.014 4.53e-02 0.119 0.110 0.009 3.50e-02
MultiScler lassosum.PseudoVal LDpred2.PseudoVal 0.103 0.119 -0.015 1.16e-06 0.102 0.110 -0.008 1.84e-01
MultiScler All.MultiPRS LDpred2.PseudoVal 0.135 0.119 0.017 1.74e-02 0.121 0.110 0.010 1.28e-02
MultiScler LDpred1.MultiPRS LDpred2.PseudoVal 0.112 0.119 -0.006 3.60e-01 0.096 0.110 -0.015 4.73e-02
MultiScler DBSLMM.PseudoVal LDpred2.PseudoVal 0.091 0.119 -0.027 2.92e-11 0.088 0.110 -0.022 7.23e-03
MultiScler LDpred1.Inf LDpred2.PseudoVal 0.090 0.119 -0.029 4.03e-09 0.078 0.110 -0.032 1.18e-03
MultiScler LDpred2.Inf LDpred2.PseudoVal 0.094 0.119 -0.025 3.44e-06 0.076 0.110 -0.034 1.43e-03
MultiScler lassosum.MultiPRS LDpred2.PseudoVal 0.128 0.119 0.009 1.97e-01 0.119 0.110 0.008 1.48e-01
MultiScler LDpred1.10FCVal LDpred2.PseudoVal 0.107 0.119 -0.011 3.90e-03 0.096 0.110 -0.015 5.69e-02
MultiScler pT+clump.MultiPRS LDpred2.PseudoVal 0.114 0.119 -0.004 5.27e-01 0.108 0.110 -0.002 7.55e-01
MultiScler SBayesR.PseudoVal LDpred2.PseudoVal 0.102 0.119 -0.017 1.85e-05 0.083 0.110 -0.027 6.94e-04
MultiScler pT+clump.10FCVal LDpred2.PseudoVal 0.090 0.119 -0.029 2.28e-12 0.092 0.110 -0.019 2.96e-02
MultiScler lassosum.10FCVal LDpred2.PseudoVal 0.115 0.119 -0.003 3.86e-01 0.097 0.110 -0.014 8.02e-02
MultiScler LDpred2.10FCVal LDpred2.PseudoVal 0.120 0.119 0.002 4.87e-01 0.108 0.110 -0.003 5.47e-01
MultiScler LDpred2.PseudoVal LDpred2.PseudoVal 0.119 0.119 0.000 1.00e+00 0.110 0.110 0.000 1.00e+00
MultiScler SBLUP.Inf LDpred2.PseudoVal 0.094 0.119 -0.025 2.96e-06 0.076 0.110 -0.035 1.14e-03
MultiScler DBSLMM.PseudoVal LDpred2.Inf 0.091 0.094 -0.003 6.74e-01 0.088 0.076 0.012 3.57e-01
MultiScler LDpred2.MultiPRS LDpred2.Inf 0.133 0.094 0.039 3.35e-08 0.119 0.076 0.043 1.12e-06
MultiScler pT+clump.10FCVal LDpred2.Inf 0.090 0.094 -0.004 5.53e-01 0.092 0.076 0.016 2.28e-01
MultiScler lassosum.10FCVal LDpred2.Inf 0.115 0.094 0.021 1.49e-09 0.097 0.076 0.020 4.82e-03
MultiScler lassosum.PseudoVal LDpred2.Inf 0.103 0.094 0.009 9.86e-02 0.102 0.076 0.026 2.48e-02
MultiScler All.MultiPRS LDpred2.Inf 0.135 0.094 0.041 3.76e-09 0.121 0.076 0.044 5.44e-07
MultiScler LDpred1.MultiPRS LDpred2.Inf 0.112 0.094 0.018 8.94e-03 0.096 0.076 0.019 4.31e-02
MultiScler LDpred2.PseudoVal LDpred2.Inf 0.119 0.094 0.025 3.44e-06 0.110 0.076 0.034 1.43e-03
MultiScler SBLUP.Inf LDpred2.Inf 0.094 0.094 0.000 1.95e-01 0.076 0.076 -0.001 1.48e-02
MultiScler LDpred1.Inf LDpred2.Inf 0.090 0.094 -0.004 2.06e-01 0.078 0.076 0.002 7.82e-01
MultiScler LDpred2.Inf LDpred2.Inf 0.094 0.094 0.000 1.00e+00 0.076 0.076 0.000 1.00e+00
MultiScler lassosum.MultiPRS LDpred2.Inf 0.128 0.094 0.034 1.56e-06 0.119 0.076 0.042 2.91e-07
MultiScler LDpred1.10FCVal LDpred2.Inf 0.107 0.094 0.013 3.24e-03 0.096 0.076 0.019 3.63e-02
MultiScler pT+clump.MultiPRS LDpred2.Inf 0.114 0.094 0.020 3.68e-03 0.108 0.076 0.032 6.82e-04
MultiScler SBayesR.PseudoVal LDpred2.Inf 0.102 0.094 0.008 8.38e-02 0.083 0.076 0.007 4.48e-01
MultiScler LDpred2.10FCVal LDpred2.Inf 0.120 0.094 0.026 3.16e-06 0.108 0.076 0.031 5.76e-03
MultiScler All.MultiPRS pT+clump.MultiPRS 0.135 0.114 0.021 2.61e-03 0.121 0.108 0.012 2.32e-02
MultiScler LDpred1.MultiPRS pT+clump.MultiPRS 0.112 0.114 -0.002 7.76e-01 0.096 0.108 -0.013 1.14e-01
MultiScler LDpred2.PseudoVal pT+clump.MultiPRS 0.119 0.114 0.004 5.27e-01 0.110 0.108 0.002 7.55e-01
MultiScler DBSLMM.PseudoVal pT+clump.MultiPRS 0.091 0.114 -0.023 1.01e-03 0.088 0.108 -0.020 1.81e-02
MultiScler LDpred1.Inf pT+clump.MultiPRS 0.090 0.114 -0.025 3.91e-04 0.078 0.108 -0.030 1.29e-03
MultiScler LDpred2.Inf pT+clump.MultiPRS 0.094 0.114 -0.020 3.68e-03 0.076 0.108 -0.032 6.82e-04
MultiScler lassosum.MultiPRS pT+clump.MultiPRS 0.128 0.114 0.013 5.50e-02 0.119 0.108 0.010 7.50e-02
MultiScler LDpred1.10FCVal pT+clump.MultiPRS 0.107 0.114 -0.007 3.18e-01 0.096 0.108 -0.013 1.13e-01
MultiScler lassosum.PseudoVal pT+clump.MultiPRS 0.103 0.114 -0.011 1.20e-01 0.102 0.108 -0.006 4.28e-01
MultiScler LDpred2.MultiPRS pT+clump.MultiPRS 0.133 0.114 0.018 8.43e-03 0.119 0.108 0.011 6.66e-02
MultiScler pT+clump.10FCVal pT+clump.MultiPRS 0.090 0.114 -0.024 5.58e-04 0.092 0.108 -0.016 1.45e-02
MultiScler lassosum.10FCVal pT+clump.MultiPRS 0.115 0.114 0.001 8.94e-01 0.097 0.108 -0.012 9.64e-02
MultiScler LDpred2.10FCVal pT+clump.MultiPRS 0.120 0.114 0.006 3.90e-01 0.108 0.108 -0.001 9.32e-01
MultiScler SBayesR.PseudoVal pT+clump.MultiPRS 0.102 0.114 -0.013 6.84e-02 0.083 0.108 -0.025 1.42e-03
MultiScler SBLUP.Inf pT+clump.MultiPRS 0.094 0.114 -0.021 3.37e-03 0.076 0.108 -0.033 5.23e-04
MultiScler pT+clump.MultiPRS pT+clump.MultiPRS 0.114 0.114 0.000 1.00e+00 0.108 0.108 0.000 1.00e+00
MultiScler lassosum.PseudoVal pT+clump.10FCVal 0.103 0.090 0.013 1.21e-03 0.102 0.092 0.010 2.21e-01
MultiScler All.MultiPRS pT+clump.10FCVal 0.135 0.090 0.045 1.18e-10 0.121 0.092 0.029 4.11e-04
MultiScler DBSLMM.PseudoVal pT+clump.10FCVal 0.091 0.090 0.001 7.36e-01 0.088 0.092 -0.004 5.67e-01
MultiScler LDpred1.Inf pT+clump.10FCVal 0.090 0.090 -0.001 9.04e-01 0.078 0.092 -0.014 2.52e-01
MultiScler LDpred2.Inf pT+clump.10FCVal 0.094 0.090 0.004 5.53e-01 0.076 0.092 -0.016 2.28e-01
MultiScler lassosum.MultiPRS pT+clump.10FCVal 0.128 0.090 0.038 8.61e-08 0.119 0.092 0.027 3.25e-03
MultiScler LDpred1.10FCVal pT+clump.10FCVal 0.107 0.090 0.017 3.98e-04 0.096 0.092 0.004 7.13e-01
MultiScler pT+clump.MultiPRS pT+clump.10FCVal 0.114 0.090 0.024 5.58e-04 0.108 0.092 0.016 1.45e-02
MultiScler LDpred2.MultiPRS pT+clump.10FCVal 0.133 0.090 0.042 1.33e-09 0.119 0.092 0.027 8.30e-04
MultiScler pT+clump.10FCVal pT+clump.10FCVal 0.090 0.090 0.000 1.00e+00 0.092 0.092 0.000 1.00e+00
MultiScler lassosum.10FCVal pT+clump.10FCVal 0.115 0.090 0.025 3.52e-06 0.097 0.092 0.005 6.70e-01
MultiScler LDpred2.10FCVal pT+clump.10FCVal 0.120 0.090 0.030 2.31e-19 0.108 0.092 0.016 2.38e-02
MultiScler SBayesR.PseudoVal pT+clump.10FCVal 0.102 0.090 0.011 3.31e-02 0.083 0.092 -0.009 4.15e-01
MultiScler LDpred1.MultiPRS pT+clump.10FCVal 0.112 0.090 0.022 1.66e-03 0.096 0.092 0.004 6.97e-01
MultiScler LDpred2.PseudoVal pT+clump.10FCVal 0.119 0.090 0.029 2.28e-12 0.110 0.092 0.019 2.96e-02
MultiScler SBLUP.Inf pT+clump.10FCVal 0.094 0.090 0.004 5.73e-01 0.076 0.092 -0.016 2.07e-01
MultiScler LDpred1.Inf SBayesR.PseudoVal 0.090 0.102 -0.012 1.20e-02 0.078 0.083 -0.005 6.27e-01
MultiScler DBSLMM.PseudoVal SBayesR.PseudoVal 0.091 0.102 -0.010 1.02e-01 0.088 0.083 0.005 6.88e-01
MultiScler lassosum.PseudoVal SBayesR.PseudoVal 0.103 0.102 0.002 7.30e-01 0.102 0.083 0.019 8.51e-02
MultiScler LDpred2.MultiPRS SBayesR.PseudoVal 0.133 0.102 0.031 7.85e-06 0.119 0.083 0.036 9.10e-06
MultiScler pT+clump.10FCVal SBayesR.PseudoVal 0.090 0.102 -0.011 3.31e-02 0.092 0.083 0.009 4.15e-01
MultiScler lassosum.10FCVal SBayesR.PseudoVal 0.115 0.102 0.014 1.99e-03 0.097 0.083 0.014 1.26e-01
MultiScler LDpred2.10FCVal SBayesR.PseudoVal 0.120 0.102 0.019 2.03e-04 0.108 0.083 0.025 1.49e-02
MultiScler All.MultiPRS SBayesR.PseudoVal 0.135 0.102 0.034 1.27e-06 0.121 0.083 0.038 5.56e-07
MultiScler LDpred1.MultiPRS SBayesR.PseudoVal 0.112 0.102 0.011 1.23e-01 0.096 0.083 0.013 2.15e-01
MultiScler LDpred2.PseudoVal SBayesR.PseudoVal 0.119 0.102 0.017 1.85e-05 0.110 0.083 0.027 6.94e-04
MultiScler SBLUP.Inf SBayesR.PseudoVal 0.094 0.102 -0.008 7.68e-02 0.076 0.083 -0.007 4.01e-01
MultiScler pT+clump.MultiPRS SBayesR.PseudoVal 0.114 0.102 0.013 6.84e-02 0.108 0.083 0.025 1.42e-03
MultiScler LDpred2.Inf SBayesR.PseudoVal 0.094 0.102 -0.008 8.38e-02 0.076 0.083 -0.007 4.48e-01
MultiScler lassosum.MultiPRS SBayesR.PseudoVal 0.128 0.102 0.026 1.75e-04 0.119 0.083 0.036 2.18e-05
MultiScler LDpred1.10FCVal SBayesR.PseudoVal 0.107 0.102 0.006 2.61e-01 0.096 0.083 0.013 2.26e-01
MultiScler SBayesR.PseudoVal SBayesR.PseudoVal 0.102 0.102 0.000 1.00e+00 0.083 0.083 0.000 1.00e+00
MultiScler All.MultiPRS SBLUP.Inf 0.135 0.094 0.042 3.21e-09 0.121 0.076 0.045 3.67e-07
MultiScler LDpred1.Inf SBLUP.Inf 0.090 0.094 -0.004 2.27e-01 0.078 0.076 0.003 7.06e-01
MultiScler LDpred2.Inf SBLUP.Inf 0.094 0.094 0.000 1.95e-01 0.076 0.076 0.001 1.48e-02
MultiScler DBSLMM.PseudoVal SBLUP.Inf 0.091 0.094 -0.002 6.96e-01 0.088 0.076 0.012 3.28e-01
MultiScler lassosum.PseudoVal SBLUP.Inf 0.103 0.094 0.010 9.21e-02 0.102 0.076 0.027 2.11e-02
MultiScler LDpred2.MultiPRS SBLUP.Inf 0.133 0.094 0.039 2.88e-08 0.119 0.076 0.043 7.51e-07
MultiScler pT+clump.10FCVal SBLUP.Inf 0.090 0.094 -0.004 5.73e-01 0.092 0.076 0.016 2.07e-01
MultiScler lassosum.10FCVal SBLUP.Inf 0.115 0.094 0.021 1.23e-09 0.097 0.076 0.021 3.62e-03
MultiScler LDpred2.10FCVal SBLUP.Inf 0.120 0.094 0.027 2.71e-06 0.108 0.076 0.032 4.75e-03
MultiScler SBayesR.PseudoVal SBLUP.Inf 0.102 0.094 0.008 7.68e-02 0.083 0.076 0.007 4.01e-01
MultiScler LDpred1.MultiPRS SBLUP.Inf 0.112 0.094 0.019 8.26e-03 0.096 0.076 0.020 3.61e-02
MultiScler LDpred2.PseudoVal SBLUP.Inf 0.119 0.094 0.025 2.96e-06 0.110 0.076 0.035 1.14e-03
MultiScler SBLUP.Inf SBLUP.Inf 0.094 0.094 0.000 1.00e+00 0.076 0.076 0.000 1.00e+00
MultiScler pT+clump.MultiPRS SBLUP.Inf 0.114 0.094 0.021 3.37e-03 0.108 0.076 0.033 5.23e-04
MultiScler lassosum.MultiPRS SBLUP.Inf 0.128 0.094 0.034 1.36e-06 0.119 0.076 0.043 1.85e-07
MultiScler LDpred1.10FCVal SBLUP.Inf 0.107 0.094 0.014 2.86e-03 0.096 0.076 0.020 3.01e-02
RheuArth lassosum.PseudoVal All.MultiPRS 0.127 0.182 -0.055 2.97e-15 0.114 0.165 -0.051 3.90e-11
RheuArth All.MultiPRS All.MultiPRS 0.182 0.182 0.000 1.00e+00 0.165 0.165 0.000 1.00e+00
RheuArth DBSLMM.PseudoVal All.MultiPRS 0.157 0.182 -0.025 3.58e-04 0.129 0.165 -0.035 1.64e-11
RheuArth LDpred1.Inf All.MultiPRS 0.138 0.182 -0.043 4.24e-10 0.114 0.165 -0.051 1.50e-14
RheuArth LDpred2.Inf All.MultiPRS 0.087 0.182 -0.095 3.39e-42 0.077 0.165 -0.088 1.47e-19
RheuArth lassosum.MultiPRS All.MultiPRS 0.169 0.182 -0.013 8.61e-16 0.146 0.165 -0.018 3.08e-08
RheuArth LDpred1.10FCVal All.MultiPRS 0.141 0.182 -0.041 4.15e-09 0.120 0.165 -0.044 4.11e-12
RheuArth pT+clump.MultiPRS All.MultiPRS 0.134 0.182 -0.047 8.71e-12 0.125 0.165 -0.039 9.79e-09
RheuArth LDpred2.MultiPRS All.MultiPRS 0.156 0.182 -0.025 2.30e-24 0.137 0.165 -0.028 3.10e-08
RheuArth pT+clump.10FCVal All.MultiPRS 0.113 0.182 -0.068 1.16e-22 0.104 0.165 -0.061 9.53e-13
RheuArth lassosum.10FCVal All.MultiPRS 0.162 0.182 -0.020 4.64e-03 0.138 0.165 -0.027 4.02e-10
RheuArth LDpred2.10FCVal All.MultiPRS 0.156 0.182 -0.025 2.55e-04 0.138 0.165 -0.026 1.23e-07
RheuArth SBayesR.PseudoVal All.MultiPRS 0.123 0.182 -0.058 4.89e-17 0.123 0.165 -0.041 4.27e-07
RheuArth LDpred1.MultiPRS All.MultiPRS 0.144 0.182 -0.037 2.89e-39 0.124 0.165 -0.041 2.63e-12
RheuArth LDpred2.PseudoVal All.MultiPRS 0.112 0.182 -0.070 7.53e-24 0.111 0.165 -0.054 2.22e-11
RheuArth SBLUP.Inf All.MultiPRS 0.113 0.182 -0.068 6.39e-23 0.101 0.165 -0.064 1.90e-14
RheuArth LDpred2.MultiPRS DBSLMM.PseudoVal 0.156 0.157 -0.001 9.21e-01 0.137 0.129 0.007 3.06e-01
RheuArth pT+clump.10FCVal DBSLMM.PseudoVal 0.113 0.157 -0.044 3.16e-18 0.104 0.129 -0.026 1.20e-02
RheuArth lassosum.PseudoVal DBSLMM.PseudoVal 0.127 0.157 -0.030 1.82e-10 0.114 0.129 -0.015 1.03e-01
RheuArth All.MultiPRS DBSLMM.PseudoVal 0.182 0.157 0.025 3.58e-04 0.165 0.129 0.035 1.64e-11
RheuArth LDpred1.MultiPRS DBSLMM.PseudoVal 0.144 0.157 -0.013 6.59e-02 0.124 0.129 -0.006 4.07e-01
RheuArth LDpred2.PseudoVal DBSLMM.PseudoVal 0.112 0.157 -0.045 3.45e-26 0.111 0.129 -0.018 3.10e-02
RheuArth DBSLMM.PseudoVal DBSLMM.PseudoVal 0.157 0.157 0.000 1.00e+00 0.129 0.129 0.000 1.00e+00
RheuArth LDpred1.Inf DBSLMM.PseudoVal 0.138 0.157 -0.019 2.73e-06 0.114 0.129 -0.016 5.22e-02
RheuArth LDpred2.Inf DBSLMM.PseudoVal 0.087 0.157 -0.070 3.82e-32 0.077 0.129 -0.053 1.05e-05
RheuArth lassosum.MultiPRS DBSLMM.PseudoVal 0.169 0.157 0.012 9.03e-02 0.146 0.129 0.017 5.10e-04
RheuArth LDpred1.10FCVal DBSLMM.PseudoVal 0.141 0.157 -0.016 4.81e-06 0.120 0.129 -0.009 2.01e-01
RheuArth pT+clump.MultiPRS DBSLMM.PseudoVal 0.134 0.157 -0.023 1.12e-03 0.125 0.129 -0.004 6.58e-01
RheuArth SBayesR.PseudoVal DBSLMM.PseudoVal 0.123 0.157 -0.033 2.24e-09 0.123 0.129 -0.006 5.92e-01
RheuArth lassosum.10FCVal DBSLMM.PseudoVal 0.162 0.157 0.005 3.37e-02 0.138 0.129 0.009 7.72e-02
RheuArth LDpred2.10FCVal DBSLMM.PseudoVal 0.156 0.157 -0.001 8.73e-01 0.138 0.129 0.009 2.38e-01
RheuArth SBLUP.Inf DBSLMM.PseudoVal 0.113 0.157 -0.044 1.48e-16 0.101 0.129 -0.028 7.76e-03
RheuArth All.MultiPRS lassosum.MultiPRS 0.182 0.169 0.013 8.61e-16 0.165 0.146 0.018 3.08e-08
RheuArth LDpred1.MultiPRS lassosum.MultiPRS 0.144 0.169 -0.024 4.20e-21 0.124 0.146 -0.023 1.59e-05
RheuArth LDpred1.Inf lassosum.MultiPRS 0.138 0.169 -0.030 1.26e-05 0.114 0.146 -0.033 6.97e-08
RheuArth LDpred2.Inf lassosum.MultiPRS 0.087 0.169 -0.082 8.05e-32 0.077 0.146 -0.070 1.65e-12
RheuArth lassosum.MultiPRS lassosum.MultiPRS 0.169 0.169 0.000 1.00e+00 0.146 0.146 0.000 1.00e+00
RheuArth DBSLMM.PseudoVal lassosum.MultiPRS 0.157 0.169 -0.012 9.03e-02 0.129 0.146 -0.017 5.10e-04
RheuArth lassosum.PseudoVal lassosum.MultiPRS 0.127 0.169 -0.042 1.77e-09 0.114 0.146 -0.032 3.72e-06
RheuArth LDpred2.MultiPRS lassosum.MultiPRS 0.156 0.169 -0.012 5.55e-05 0.137 0.146 -0.010 1.21e-01
RheuArth pT+clump.10FCVal lassosum.MultiPRS 0.113 0.169 -0.055 2.08e-15 0.104 0.146 -0.043 1.52e-05
RheuArth lassosum.10FCVal lassosum.MultiPRS 0.162 0.169 -0.007 3.38e-01 0.138 0.146 -0.008 3.16e-04
RheuArth LDpred2.10FCVal lassosum.MultiPRS 0.156 0.169 -0.012 7.48e-02 0.138 0.146 -0.008 1.83e-01
RheuArth SBayesR.PseudoVal lassosum.MultiPRS 0.123 0.169 -0.045 7.20e-11 0.123 0.146 -0.023 1.07e-02
RheuArth LDpred2.PseudoVal lassosum.MultiPRS 0.112 0.169 -0.057 2.48e-16 0.111 0.146 -0.035 8.35e-05
RheuArth SBLUP.Inf lassosum.MultiPRS 0.113 0.169 -0.055 1.44e-15 0.101 0.146 -0.045 3.70e-08
RheuArth pT+clump.MultiPRS lassosum.MultiPRS 0.134 0.169 -0.034 7.44e-07 0.125 0.146 -0.021 8.60e-03
RheuArth LDpred1.10FCVal lassosum.MultiPRS 0.141 0.169 -0.028 6.31e-05 0.120 0.146 -0.026 7.25e-06
RheuArth All.MultiPRS lassosum.PseudoVal 0.182 0.127 0.055 2.97e-15 0.165 0.114 0.051 3.90e-11
RheuArth LDpred1.MultiPRS lassosum.PseudoVal 0.144 0.127 0.017 1.28e-02 0.124 0.114 0.010 1.88e-01
RheuArth LDpred2.PseudoVal lassosum.PseudoVal 0.112 0.127 -0.015 6.26e-03 0.111 0.114 -0.003 7.80e-01
RheuArth DBSLMM.PseudoVal lassosum.PseudoVal 0.157 0.127 0.030 1.82e-10 0.129 0.114 0.015 1.03e-01
RheuArth LDpred1.Inf lassosum.PseudoVal 0.138 0.127 0.012 1.17e-03 0.114 0.114 0.000 9.71e-01
RheuArth LDpred2.Inf lassosum.PseudoVal 0.087 0.127 -0.040 1.98e-22 0.077 0.114 -0.037 6.67e-06
RheuArth lassosum.MultiPRS lassosum.PseudoVal 0.169 0.127 0.042 1.77e-09 0.146 0.114 0.032 3.72e-06
RheuArth LDpred1.10FCVal lassosum.PseudoVal 0.141 0.127 0.014 2.77e-04 0.120 0.114 0.006 4.27e-01
RheuArth lassosum.PseudoVal lassosum.PseudoVal 0.127 0.127 0.000 1.00e+00 0.114 0.114 0.000 1.00e+00
RheuArth LDpred2.MultiPRS lassosum.PseudoVal 0.156 0.127 0.029 2.44e-05 0.137 0.114 0.023 9.48e-03
RheuArth pT+clump.10FCVal lassosum.PseudoVal 0.113 0.127 -0.013 2.35e-02 0.104 0.114 -0.010 3.87e-01
RheuArth lassosum.10FCVal lassosum.PseudoVal 0.162 0.127 0.035 3.86e-19 0.138 0.114 0.024 2.29e-03
RheuArth LDpred2.10FCVal lassosum.PseudoVal 0.156 0.127 0.029 6.70e-12 0.138 0.114 0.024 5.19e-03
RheuArth SBayesR.PseudoVal lassosum.PseudoVal 0.123 0.127 -0.003 4.19e-01 0.123 0.114 0.009 2.72e-01
RheuArth SBLUP.Inf lassosum.PseudoVal 0.113 0.127 -0.014 1.17e-04 0.101 0.114 -0.013 6.46e-02
RheuArth pT+clump.MultiPRS lassosum.PseudoVal 0.134 0.127 0.007 2.87e-01 0.125 0.114 0.011 2.31e-01
RheuArth All.MultiPRS lassosum.10FCVal 0.182 0.162 0.020 4.64e-03 0.165 0.138 0.027 4.02e-10
RheuArth LDpred1.MultiPRS lassosum.10FCVal 0.144 0.162 -0.018 1.00e-02 0.124 0.138 -0.014 2.36e-02
RheuArth LDpred1.Inf lassosum.10FCVal 0.138 0.162 -0.024 2.75e-11 0.114 0.138 -0.024 7.85e-04
RheuArth LDpred2.Inf lassosum.10FCVal 0.087 0.162 -0.075 6.19e-44 0.077 0.138 -0.061 1.91e-08
RheuArth lassosum.MultiPRS lassosum.10FCVal 0.169 0.162 0.007 3.38e-01 0.146 0.138 0.008 3.16e-04
RheuArth DBSLMM.PseudoVal lassosum.10FCVal 0.157 0.162 -0.005 3.37e-02 0.129 0.138 -0.009 7.72e-02
RheuArth lassosum.PseudoVal lassosum.10FCVal 0.127 0.162 -0.035 3.86e-19 0.114 0.138 -0.024 2.29e-03
RheuArth LDpred2.MultiPRS lassosum.10FCVal 0.156 0.162 -0.006 4.05e-01 0.137 0.138 -0.001 8.50e-01
RheuArth pT+clump.10FCVal lassosum.10FCVal 0.113 0.162 -0.049 8.27e-22 0.104 0.138 -0.034 8.28e-04
RheuArth lassosum.10FCVal lassosum.10FCVal 0.162 0.162 0.000 1.00e+00 0.138 0.138 0.000 1.00e+00
RheuArth LDpred2.10FCVal lassosum.10FCVal 0.156 0.162 -0.006 7.38e-02 0.138 0.138 0.000 9.81e-01
RheuArth SBayesR.PseudoVal lassosum.10FCVal 0.123 0.162 -0.039 2.27e-14 0.123 0.138 -0.015 1.50e-01
RheuArth LDpred2.PseudoVal lassosum.10FCVal 0.112 0.162 -0.050 1.66e-30 0.111 0.138 -0.027 2.10e-03
RheuArth SBLUP.Inf lassosum.10FCVal 0.113 0.162 -0.049 3.80e-25 0.101 0.138 -0.037 1.01e-04
RheuArth pT+clump.MultiPRS lassosum.10FCVal 0.134 0.162 -0.028 6.46e-05 0.125 0.138 -0.013 1.37e-01
RheuArth LDpred1.10FCVal lassosum.10FCVal 0.141 0.162 -0.021 1.66e-10 0.120 0.138 -0.018 7.91e-03
RheuArth DBSLMM.PseudoVal LDpred1.MultiPRS 0.157 0.144 0.013 6.59e-02 0.129 0.124 0.006 4.07e-01
RheuArth LDpred2.MultiPRS LDpred1.MultiPRS 0.156 0.144 0.012 7.85e-04 0.137 0.124 0.013 7.00e-02
RheuArth pT+clump.10FCVal LDpred1.MultiPRS 0.113 0.144 -0.031 1.01e-05 0.104 0.124 -0.020 7.48e-02
RheuArth lassosum.10FCVal LDpred1.MultiPRS 0.162 0.144 0.018 1.00e-02 0.138 0.124 0.014 2.36e-02
RheuArth lassosum.PseudoVal LDpred1.MultiPRS 0.127 0.144 -0.017 1.28e-02 0.114 0.124 -0.010 1.88e-01
RheuArth All.MultiPRS LDpred1.MultiPRS 0.182 0.144 0.037 2.89e-39 0.165 0.124 0.041 2.63e-12
RheuArth LDpred1.MultiPRS LDpred1.MultiPRS 0.144 0.144 0.000 1.00e+00 0.124 0.124 0.000 1.00e+00
RheuArth LDpred2.PseudoVal LDpred1.MultiPRS 0.112 0.144 -0.033 3.04e-06 0.111 0.124 -0.013 2.04e-01
RheuArth SBLUP.Inf LDpred1.MultiPRS 0.113 0.144 -0.031 8.80e-06 0.101 0.124 -0.023 5.88e-04
RheuArth LDpred1.Inf LDpred1.MultiPRS 0.138 0.144 -0.006 4.06e-01 0.114 0.124 -0.010 8.81e-04
RheuArth LDpred2.Inf LDpred1.MultiPRS 0.087 0.144 -0.057 2.38e-16 0.077 0.124 -0.047 1.39e-08
RheuArth lassosum.MultiPRS LDpred1.MultiPRS 0.169 0.144 0.024 4.20e-21 0.146 0.124 0.023 1.59e-05
RheuArth LDpred1.10FCVal LDpred1.MultiPRS 0.141 0.144 -0.003 6.42e-01 0.120 0.124 -0.003 1.98e-01
RheuArth pT+clump.MultiPRS LDpred1.MultiPRS 0.134 0.144 -0.010 1.55e-01 0.125 0.124 0.001 8.76e-01
RheuArth SBayesR.PseudoVal LDpred1.MultiPRS 0.123 0.144 -0.021 2.84e-03 0.123 0.124 0.000 9.68e-01
RheuArth LDpred2.10FCVal LDpred1.MultiPRS 0.156 0.144 0.012 7.94e-02 0.138 0.124 0.015 4.39e-02
RheuArth All.MultiPRS LDpred1.Inf 0.182 0.138 0.043 4.24e-10 0.165 0.114 0.051 1.50e-14
RheuArth LDpred1.Inf LDpred1.Inf 0.138 0.138 0.000 1.00e+00 0.114 0.114 0.000 1.00e+00
RheuArth LDpred2.Inf LDpred1.Inf 0.087 0.138 -0.051 3.18e-46 0.077 0.114 -0.037 3.05e-07
RheuArth DBSLMM.PseudoVal LDpred1.Inf 0.157 0.138 0.019 2.73e-06 0.129 0.114 0.016 5.22e-02
RheuArth lassosum.PseudoVal LDpred1.Inf 0.127 0.138 -0.012 1.17e-03 0.114 0.114 0.000 9.71e-01
RheuArth LDpred2.MultiPRS LDpred1.Inf 0.156 0.138 0.018 1.03e-02 0.137 0.114 0.023 3.02e-03
RheuArth pT+clump.10FCVal LDpred1.Inf 0.113 0.138 -0.025 1.24e-05 0.104 0.114 -0.010 3.87e-01
RheuArth lassosum.10FCVal LDpred1.Inf 0.162 0.138 0.024 2.75e-11 0.138 0.114 0.024 7.85e-04
RheuArth LDpred2.10FCVal LDpred1.Inf 0.156 0.138 0.018 1.69e-06 0.138 0.114 0.024 1.45e-03
RheuArth SBayesR.PseudoVal LDpred1.Inf 0.123 0.138 -0.015 9.09e-05 0.123 0.114 0.010 2.18e-01
RheuArth LDpred1.MultiPRS LDpred1.Inf 0.144 0.138 0.006 4.06e-01 0.124 0.114 0.010 8.81e-04
RheuArth LDpred2.PseudoVal LDpred1.Inf 0.112 0.138 -0.027 3.67e-07 0.111 0.114 -0.003 7.88e-01
RheuArth SBLUP.Inf LDpred1.Inf 0.113 0.138 -0.025 7.00e-21 0.101 0.114 -0.013 1.74e-02
RheuArth pT+clump.MultiPRS LDpred1.Inf 0.134 0.138 -0.004 5.52e-01 0.125 0.114 0.011 2.31e-01
RheuArth lassosum.MultiPRS LDpred1.Inf 0.169 0.138 0.030 1.26e-05 0.146 0.114 0.033 6.97e-08
RheuArth LDpred1.10FCVal LDpred1.Inf 0.141 0.138 0.003 2.47e-01 0.120 0.114 0.006 1.43e-01
RheuArth LDpred1.Inf LDpred1.10FCVal 0.138 0.141 -0.003 2.47e-01 0.114 0.120 -0.006 1.43e-01
RheuArth DBSLMM.PseudoVal LDpred1.10FCVal 0.157 0.141 0.016 4.81e-06 0.129 0.120 0.009 2.01e-01
RheuArth lassosum.PseudoVal LDpred1.10FCVal 0.127 0.141 -0.014 2.77e-04 0.114 0.120 -0.006 4.27e-01
RheuArth LDpred2.MultiPRS LDpred1.10FCVal 0.156 0.141 0.015 2.77e-02 0.137 0.120 0.017 2.87e-02
RheuArth pT+clump.10FCVal LDpred1.10FCVal 0.113 0.141 -0.028 7.20e-07 0.104 0.120 -0.016 1.44e-01
RheuArth lassosum.10FCVal LDpred1.10FCVal 0.162 0.141 0.021 1.66e-10 0.138 0.120 0.018 7.91e-03
RheuArth LDpred2.10FCVal LDpred1.10FCVal 0.156 0.141 0.015 3.77e-05 0.138 0.120 0.018 1.75e-02
RheuArth All.MultiPRS LDpred1.10FCVal 0.182 0.141 0.041 4.15e-09 0.165 0.120 0.044 4.11e-12
RheuArth LDpred1.MultiPRS LDpred1.10FCVal 0.144 0.141 0.003 6.42e-01 0.124 0.120 0.003 1.98e-01
RheuArth LDpred2.PseudoVal LDpred1.10FCVal 0.112 0.141 -0.029 4.42e-09 0.111 0.120 -0.009 3.55e-01
RheuArth SBLUP.Inf LDpred1.10FCVal 0.113 0.141 -0.028 4.12e-14 0.101 0.120 -0.019 8.96e-03
RheuArth pT+clump.MultiPRS LDpred1.10FCVal 0.134 0.141 -0.007 3.37e-01 0.125 0.120 0.005 6.14e-01
RheuArth LDpred2.Inf LDpred1.10FCVal 0.087 0.141 -0.054 1.75e-34 0.077 0.120 -0.044 8.72e-07
RheuArth lassosum.MultiPRS LDpred1.10FCVal 0.169 0.141 0.028 6.31e-05 0.146 0.120 0.026 7.25e-06
RheuArth LDpred1.10FCVal LDpred1.10FCVal 0.141 0.141 0.000 1.00e+00 0.120 0.120 0.000 1.00e+00
RheuArth SBayesR.PseudoVal LDpred1.10FCVal 0.123 0.141 -0.018 9.34e-05 0.123 0.120 0.003 7.36e-01
RheuArth LDpred2.MultiPRS LDpred2.MultiPRS 0.156 0.156 0.000 1.00e+00 0.137 0.137 0.000 1.00e+00
RheuArth lassosum.PseudoVal LDpred2.MultiPRS 0.127 0.156 -0.029 2.44e-05 0.114 0.137 -0.023 9.48e-03
RheuArth All.MultiPRS LDpred2.MultiPRS 0.182 0.156 0.025 2.30e-24 0.165 0.137 0.028 3.10e-08
RheuArth LDpred1.MultiPRS LDpred2.MultiPRS 0.144 0.156 -0.012 7.85e-04 0.124 0.137 -0.013 7.00e-02
RheuArth DBSLMM.PseudoVal LDpred2.MultiPRS 0.157 0.156 0.001 9.21e-01 0.129 0.137 -0.007 3.06e-01
RheuArth LDpred1.Inf LDpred2.MultiPRS 0.138 0.156 -0.018 1.03e-02 0.114 0.137 -0.023 3.02e-03
RheuArth LDpred2.Inf LDpred2.MultiPRS 0.087 0.156 -0.069 3.87e-23 0.077 0.137 -0.060 1.19e-10
RheuArth lassosum.MultiPRS LDpred2.MultiPRS 0.169 0.156 0.012 5.55e-05 0.146 0.137 0.010 1.21e-01
RheuArth LDpred1.10FCVal LDpred2.MultiPRS 0.141 0.156 -0.015 2.77e-02 0.120 0.137 -0.017 2.87e-02
RheuArth pT+clump.MultiPRS LDpred2.MultiPRS 0.134 0.156 -0.022 1.62e-03 0.125 0.137 -0.012 2.26e-01
RheuArth SBayesR.PseudoVal LDpred2.MultiPRS 0.123 0.156 -0.033 2.48e-06 0.123 0.137 -0.014 1.90e-01
RheuArth pT+clump.10FCVal LDpred2.MultiPRS 0.113 0.156 -0.043 8.15e-10 0.104 0.137 -0.033 2.97e-03
RheuArth lassosum.10FCVal LDpred2.MultiPRS 0.162 0.156 0.006 4.05e-01 0.138 0.137 0.001 8.50e-01
RheuArth LDpred2.10FCVal LDpred2.MultiPRS 0.156 0.156 0.000 9.89e-01 0.138 0.137 0.001 1.82e-01
RheuArth LDpred2.PseudoVal LDpred2.MultiPRS 0.112 0.156 -0.045 1.54e-10 0.111 0.137 -0.026 1.31e-04
RheuArth SBLUP.Inf LDpred2.MultiPRS 0.113 0.156 -0.043 7.02e-10 0.101 0.137 -0.036 4.40e-05
RheuArth LDpred2.MultiPRS LDpred2.10FCVal 0.156 0.156 0.000 9.89e-01 0.137 0.138 -0.001 1.82e-01
RheuArth pT+clump.10FCVal LDpred2.10FCVal 0.113 0.156 -0.043 1.02e-14 0.104 0.138 -0.034 2.01e-03
RheuArth lassosum.PseudoVal LDpred2.10FCVal 0.127 0.156 -0.029 6.70e-12 0.114 0.138 -0.024 5.19e-03
RheuArth All.MultiPRS LDpred2.10FCVal 0.182 0.156 0.025 2.55e-04 0.165 0.138 0.026 1.23e-07
RheuArth LDpred1.MultiPRS LDpred2.10FCVal 0.144 0.156 -0.012 7.94e-02 0.124 0.138 -0.015 4.39e-02
RheuArth LDpred2.PseudoVal LDpred2.10FCVal 0.112 0.156 -0.045 6.36e-44 0.111 0.138 -0.027 2.45e-05
RheuArth DBSLMM.PseudoVal LDpred2.10FCVal 0.157 0.156 0.001 8.73e-01 0.129 0.138 -0.009 2.38e-01
RheuArth LDpred1.Inf LDpred2.10FCVal 0.138 0.156 -0.018 1.69e-06 0.114 0.138 -0.024 1.45e-03
RheuArth LDpred2.Inf LDpred2.10FCVal 0.087 0.156 -0.069 4.33e-54 0.077 0.138 -0.061 1.27e-11
RheuArth lassosum.MultiPRS LDpred2.10FCVal 0.169 0.156 0.012 7.48e-02 0.146 0.138 0.008 1.83e-01
RheuArth LDpred1.10FCVal LDpred2.10FCVal 0.141 0.156 -0.015 3.77e-05 0.120 0.138 -0.018 1.75e-02
RheuArth pT+clump.MultiPRS LDpred2.10FCVal 0.134 0.156 -0.022 1.55e-03 0.125 0.138 -0.013 1.73e-01
RheuArth SBayesR.PseudoVal LDpred2.10FCVal 0.123 0.156 -0.033 4.30e-11 0.123 0.138 -0.015 1.39e-01
RheuArth lassosum.10FCVal LDpred2.10FCVal 0.162 0.156 0.006 7.38e-02 0.138 0.138 0.000 9.81e-01
RheuArth LDpred2.10FCVal LDpred2.10FCVal 0.156 0.156 0.000 1.00e+00 0.138 0.138 0.000 1.00e+00
RheuArth SBLUP.Inf LDpred2.10FCVal 0.113 0.156 -0.043 1.49e-24 0.101 0.138 -0.037 1.29e-05
RheuArth LDpred2.MultiPRS LDpred2.PseudoVal 0.156 0.112 0.045 1.54e-10 0.137 0.111 0.026 1.31e-04
RheuArth lassosum.PseudoVal LDpred2.PseudoVal 0.127 0.112 0.015 6.26e-03 0.114 0.111 0.003 7.80e-01
RheuArth All.MultiPRS LDpred2.PseudoVal 0.182 0.112 0.070 7.53e-24 0.165 0.111 0.054 2.22e-11
RheuArth LDpred1.MultiPRS LDpred2.PseudoVal 0.144 0.112 0.033 3.04e-06 0.124 0.111 0.013 2.04e-01
RheuArth DBSLMM.PseudoVal LDpred2.PseudoVal 0.157 0.112 0.045 3.45e-26 0.129 0.111 0.018 3.10e-02
RheuArth LDpred1.Inf LDpred2.PseudoVal 0.138 0.112 0.027 3.67e-07 0.114 0.111 0.003 7.88e-01
RheuArth LDpred2.Inf LDpred2.PseudoVal 0.087 0.112 -0.025 6.96e-05 0.077 0.111 -0.034 6.09e-03
RheuArth lassosum.MultiPRS LDpred2.PseudoVal 0.169 0.112 0.057 2.48e-16 0.146 0.111 0.035 8.35e-05
RheuArth LDpred1.10FCVal LDpred2.PseudoVal 0.141 0.112 0.029 4.42e-09 0.120 0.111 0.009 3.55e-01
RheuArth pT+clump.MultiPRS LDpred2.PseudoVal 0.134 0.112 0.023 1.22e-03 0.125 0.111 0.014 2.07e-01
RheuArth SBayesR.PseudoVal LDpred2.PseudoVal 0.123 0.112 0.012 5.44e-02 0.123 0.111 0.012 3.17e-01
RheuArth pT+clump.10FCVal LDpred2.PseudoVal 0.113 0.112 0.002 7.52e-01 0.104 0.111 -0.007 5.26e-01
RheuArth lassosum.10FCVal LDpred2.PseudoVal 0.162 0.112 0.050 1.66e-30 0.138 0.111 0.027 2.10e-03
RheuArth LDpred2.10FCVal LDpred2.PseudoVal 0.156 0.112 0.045 6.36e-44 0.138 0.111 0.027 2.45e-05
RheuArth LDpred2.PseudoVal LDpred2.PseudoVal 0.112 0.112 0.000 1.00e+00 0.111 0.111 0.000 1.00e+00
RheuArth SBLUP.Inf LDpred2.PseudoVal 0.113 0.112 0.002 7.77e-01 0.101 0.111 -0.010 4.06e-01
RheuArth DBSLMM.PseudoVal LDpred2.Inf 0.157 0.087 0.070 3.82e-32 0.129 0.077 0.053 1.05e-05
RheuArth LDpred2.MultiPRS LDpred2.Inf 0.156 0.087 0.069 3.87e-23 0.137 0.077 0.060 1.19e-10
RheuArth pT+clump.10FCVal LDpred2.Inf 0.113 0.087 0.026 6.56e-05 0.104 0.077 0.027 4.01e-02
RheuArth lassosum.10FCVal LDpred2.Inf 0.162 0.087 0.075 6.19e-44 0.138 0.077 0.061 1.91e-08
RheuArth lassosum.PseudoVal LDpred2.Inf 0.127 0.087 0.040 1.98e-22 0.114 0.077 0.037 6.67e-06
RheuArth All.MultiPRS LDpred2.Inf 0.182 0.087 0.095 3.39e-42 0.165 0.077 0.088 1.47e-19
RheuArth LDpred1.MultiPRS LDpred2.Inf 0.144 0.087 0.057 2.38e-16 0.124 0.077 0.047 1.39e-08
RheuArth LDpred2.PseudoVal LDpred2.Inf 0.112 0.087 0.025 6.96e-05 0.111 0.077 0.034 6.09e-03
RheuArth SBLUP.Inf LDpred2.Inf 0.113 0.087 0.026 6.79e-71 0.101 0.077 0.024 1.81e-16
RheuArth LDpred1.Inf LDpred2.Inf 0.138 0.087 0.051 3.18e-46 0.114 0.077 0.037 3.05e-07
RheuArth LDpred2.Inf LDpred2.Inf 0.087 0.087 0.000 1.00e+00 0.077 0.077 0.000 1.00e+00
RheuArth lassosum.MultiPRS LDpred2.Inf 0.169 0.087 0.082 8.05e-32 0.146 0.077 0.070 1.65e-12
RheuArth LDpred1.10FCVal LDpred2.Inf 0.141 0.087 0.054 1.75e-34 0.120 0.077 0.044 8.72e-07
RheuArth pT+clump.MultiPRS LDpred2.Inf 0.134 0.087 0.047 1.67e-11 0.125 0.077 0.048 4.84e-06
RheuArth SBayesR.PseudoVal LDpred2.Inf 0.123 0.087 0.036 5.54e-28 0.123 0.077 0.047 3.47e-12
RheuArth LDpred2.10FCVal LDpred2.Inf 0.156 0.087 0.069 4.33e-54 0.138 0.077 0.061 1.27e-11
RheuArth All.MultiPRS pT+clump.MultiPRS 0.182 0.134 0.047 8.71e-12 0.165 0.125 0.039 9.79e-09
RheuArth LDpred1.MultiPRS pT+clump.MultiPRS 0.144 0.134 0.010 1.55e-01 0.124 0.125 -0.001 8.76e-01
RheuArth LDpred2.PseudoVal pT+clump.MultiPRS 0.112 0.134 -0.023 1.22e-03 0.111 0.125 -0.014 2.07e-01
RheuArth DBSLMM.PseudoVal pT+clump.MultiPRS 0.157 0.134 0.023 1.12e-03 0.129 0.125 0.004 6.58e-01
RheuArth LDpred1.Inf pT+clump.MultiPRS 0.138 0.134 0.004 5.52e-01 0.114 0.125 -0.011 2.31e-01
RheuArth LDpred2.Inf pT+clump.MultiPRS 0.087 0.134 -0.047 1.67e-11 0.077 0.125 -0.048 4.84e-06
RheuArth lassosum.MultiPRS pT+clump.MultiPRS 0.169 0.134 0.034 7.44e-07 0.146 0.125 0.021 8.60e-03
RheuArth LDpred1.10FCVal pT+clump.MultiPRS 0.141 0.134 0.007 3.37e-01 0.120 0.125 -0.005 6.14e-01
RheuArth lassosum.PseudoVal pT+clump.MultiPRS 0.127 0.134 -0.007 2.87e-01 0.114 0.125 -0.011 2.31e-01
RheuArth LDpred2.MultiPRS pT+clump.MultiPRS 0.156 0.134 0.022 1.62e-03 0.137 0.125 0.012 2.26e-01
RheuArth pT+clump.10FCVal pT+clump.MultiPRS 0.113 0.134 -0.021 2.78e-03 0.104 0.125 -0.021 1.64e-04
RheuArth lassosum.10FCVal pT+clump.MultiPRS 0.162 0.134 0.028 6.46e-05 0.138 0.125 0.013 1.37e-01
RheuArth LDpred2.10FCVal pT+clump.MultiPRS 0.156 0.134 0.022 1.55e-03 0.138 0.125 0.013 1.73e-01
RheuArth SBayesR.PseudoVal pT+clump.MultiPRS 0.123 0.134 -0.011 1.21e-01 0.123 0.125 -0.002 8.15e-01
RheuArth SBLUP.Inf pT+clump.MultiPRS 0.113 0.134 -0.021 2.68e-03 0.101 0.125 -0.024 1.10e-02
RheuArth pT+clump.MultiPRS pT+clump.MultiPRS 0.134 0.134 0.000 1.00e+00 0.125 0.125 0.000 1.00e+00
RheuArth lassosum.PseudoVal pT+clump.10FCVal 0.127 0.113 0.013 2.35e-02 0.114 0.104 0.010 3.87e-01
RheuArth All.MultiPRS pT+clump.10FCVal 0.182 0.113 0.068 1.16e-22 0.165 0.104 0.061 9.53e-13
RheuArth DBSLMM.PseudoVal pT+clump.10FCVal 0.157 0.113 0.044 3.16e-18 0.129 0.104 0.026 1.20e-02
RheuArth LDpred1.Inf pT+clump.10FCVal 0.138 0.113 0.025 1.24e-05 0.114 0.104 0.010 3.87e-01
RheuArth LDpred2.Inf pT+clump.10FCVal 0.087 0.113 -0.026 6.56e-05 0.077 0.104 -0.027 4.01e-02
RheuArth lassosum.MultiPRS pT+clump.10FCVal 0.169 0.113 0.055 2.08e-15 0.146 0.104 0.043 1.52e-05
RheuArth LDpred1.10FCVal pT+clump.10FCVal 0.141 0.113 0.028 7.20e-07 0.120 0.104 0.016 1.44e-01
RheuArth pT+clump.MultiPRS pT+clump.10FCVal 0.134 0.113 0.021 2.78e-03 0.125 0.104 0.021 1.64e-04
RheuArth LDpred2.MultiPRS pT+clump.10FCVal 0.156 0.113 0.043 8.15e-10 0.137 0.104 0.033 2.97e-03
RheuArth pT+clump.10FCVal pT+clump.10FCVal 0.113 0.113 0.000 1.00e+00 0.104 0.104 0.000 1.00e+00
RheuArth lassosum.10FCVal pT+clump.10FCVal 0.162 0.113 0.049 8.27e-22 0.138 0.104 0.034 8.28e-04
RheuArth LDpred2.10FCVal pT+clump.10FCVal 0.156 0.113 0.043 1.02e-14 0.138 0.104 0.034 2.01e-03
RheuArth SBayesR.PseudoVal pT+clump.10FCVal 0.123 0.113 0.010 5.15e-02 0.123 0.104 0.020 5.55e-02
RheuArth LDpred1.MultiPRS pT+clump.10FCVal 0.144 0.113 0.031 1.01e-05 0.124 0.104 0.020 7.48e-02
RheuArth LDpred2.PseudoVal pT+clump.10FCVal 0.112 0.113 -0.002 7.52e-01 0.111 0.104 0.007 5.26e-01
RheuArth SBLUP.Inf pT+clump.10FCVal 0.113 0.113 0.000 9.87e-01 0.101 0.104 -0.003 8.18e-01
RheuArth LDpred1.Inf SBayesR.PseudoVal 0.138 0.123 0.015 9.09e-05 0.114 0.123 -0.010 2.18e-01
RheuArth DBSLMM.PseudoVal SBayesR.PseudoVal 0.157 0.123 0.033 2.24e-09 0.129 0.123 0.006 5.92e-01
RheuArth lassosum.PseudoVal SBayesR.PseudoVal 0.127 0.123 0.003 4.19e-01 0.114 0.123 -0.009 2.72e-01
RheuArth LDpred2.MultiPRS SBayesR.PseudoVal 0.156 0.123 0.033 2.48e-06 0.137 0.123 0.014 1.90e-01
RheuArth pT+clump.10FCVal SBayesR.PseudoVal 0.113 0.123 -0.010 5.15e-02 0.104 0.123 -0.020 5.55e-02
RheuArth lassosum.10FCVal SBayesR.PseudoVal 0.162 0.123 0.039 2.27e-14 0.138 0.123 0.015 1.50e-01
RheuArth LDpred2.10FCVal SBayesR.PseudoVal 0.156 0.123 0.033 4.30e-11 0.138 0.123 0.015 1.39e-01
RheuArth All.MultiPRS SBayesR.PseudoVal 0.182 0.123 0.058 4.89e-17 0.165 0.123 0.041 4.27e-07
RheuArth LDpred1.MultiPRS SBayesR.PseudoVal 0.144 0.123 0.021 2.84e-03 0.124 0.123 0.000 9.68e-01
RheuArth LDpred2.PseudoVal SBayesR.PseudoVal 0.112 0.123 -0.012 5.44e-02 0.111 0.123 -0.012 3.17e-01
RheuArth SBLUP.Inf SBayesR.PseudoVal 0.113 0.123 -0.010 3.02e-04 0.101 0.123 -0.022 8.97e-05
RheuArth pT+clump.MultiPRS SBayesR.PseudoVal 0.134 0.123 0.011 1.21e-01 0.125 0.123 0.002 8.15e-01
RheuArth LDpred2.Inf SBayesR.PseudoVal 0.087 0.123 -0.036 5.54e-28 0.077 0.123 -0.047 3.47e-12
RheuArth lassosum.MultiPRS SBayesR.PseudoVal 0.169 0.123 0.045 7.20e-11 0.146 0.123 0.023 1.07e-02
RheuArth LDpred1.10FCVal SBayesR.PseudoVal 0.141 0.123 0.018 9.34e-05 0.120 0.123 -0.003 7.36e-01
RheuArth SBayesR.PseudoVal SBayesR.PseudoVal 0.123 0.123 0.000 1.00e+00 0.123 0.123 0.000 1.00e+00
RheuArth All.MultiPRS SBLUP.Inf 0.182 0.113 0.068 6.39e-23 0.165 0.101 0.064 1.90e-14
RheuArth LDpred1.Inf SBLUP.Inf 0.138 0.113 0.025 7.00e-21 0.114 0.101 0.013 1.74e-02
RheuArth LDpred2.Inf SBLUP.Inf 0.087 0.113 -0.026 6.79e-71 0.077 0.101 -0.024 1.81e-16
RheuArth DBSLMM.PseudoVal SBLUP.Inf 0.157 0.113 0.044 1.48e-16 0.129 0.101 0.028 7.76e-03
RheuArth lassosum.PseudoVal SBLUP.Inf 0.127 0.113 0.014 1.17e-04 0.114 0.101 0.013 6.46e-02
RheuArth LDpred2.MultiPRS SBLUP.Inf 0.156 0.113 0.043 7.02e-10 0.137 0.101 0.036 4.40e-05
RheuArth pT+clump.10FCVal SBLUP.Inf 0.113 0.113 0.000 9.87e-01 0.104 0.101 0.003 8.18e-01
RheuArth lassosum.10FCVal SBLUP.Inf 0.162 0.113 0.049 3.80e-25 0.138 0.101 0.037 1.01e-04
RheuArth LDpred2.10FCVal SBLUP.Inf 0.156 0.113 0.043 1.49e-24 0.138 0.101 0.037 1.29e-05
RheuArth SBayesR.PseudoVal SBLUP.Inf 0.123 0.113 0.010 3.02e-04 0.123 0.101 0.022 8.97e-05
RheuArth LDpred1.MultiPRS SBLUP.Inf 0.144 0.113 0.031 8.80e-06 0.124 0.101 0.023 5.88e-04
RheuArth LDpred2.PseudoVal SBLUP.Inf 0.112 0.113 -0.002 7.77e-01 0.111 0.101 0.010 4.06e-01
RheuArth SBLUP.Inf SBLUP.Inf 0.113 0.113 0.000 1.00e+00 0.101 0.101 0.000 1.00e+00
RheuArth pT+clump.MultiPRS SBLUP.Inf 0.134 0.113 0.021 2.68e-03 0.125 0.101 0.024 1.10e-02
RheuArth lassosum.MultiPRS SBLUP.Inf 0.169 0.113 0.055 1.44e-15 0.146 0.101 0.045 3.70e-08
RheuArth LDpred1.10FCVal SBLUP.Inf 0.141 0.113 0.028 4.12e-14 0.120 0.101 0.019 8.96e-03
Prostate_Cancer lassosum.10FCVal All.MultiPRS 0.182 0.185 -0.003 6.23e-01 0.179 0.183 -0.004 4.18e-01
Prostate_Cancer All.MultiPRS All.MultiPRS 0.185 0.185 0.000 1.00e+00 0.183 0.183 0.000 1.00e+00
Prostate_Cancer DBSLMM.PseudoVal All.MultiPRS 0.179 0.185 -0.006 3.80e-01 0.166 0.183 -0.018 3.09e-04
Prostate_Cancer LDpred1.Inf All.MultiPRS 0.142 0.185 -0.043 5.36e-10 0.133 0.183 -0.050 1.00e-10
Prostate_Cancer LDpred2.Inf All.MultiPRS 0.136 0.185 -0.049 1.63e-12 0.126 0.183 -0.057 1.65e-12
Prostate_Cancer lassosum.MultiPRS All.MultiPRS 0.188 0.185 0.003 6.95e-01 0.179 0.183 -0.004 3.20e-01
Prostate_Cancer LDpred1.10FCVal All.MultiPRS 0.159 0.185 -0.026 1.85e-04 0.146 0.183 -0.037 8.28e-09
Prostate_Cancer pT+clump.MultiPRS All.MultiPRS 0.165 0.185 -0.020 3.63e-03 0.173 0.183 -0.011 8.22e-02
Prostate_Cancer LDpred2.MultiPRS All.MultiPRS 0.191 0.185 0.006 4.00e-01 0.183 0.183 0.000 9.78e-01
Prostate_Cancer pT+clump.10FCVal All.MultiPRS 0.150 0.185 -0.035 3.09e-07 0.164 0.183 -0.019 7.43e-03
Prostate_Cancer lassosum.PseudoVal All.MultiPRS 0.169 0.185 -0.016 1.97e-02 0.163 0.183 -0.020 4.26e-04
Prostate_Cancer LDpred2.10FCVal All.MultiPRS 0.188 0.185 0.003 6.35e-01 0.187 0.183 0.004 3.31e-01
Prostate_Cancer SBayesR.PseudoVal All.MultiPRS 0.183 0.185 -0.002 7.76e-01 0.182 0.183 -0.001 7.93e-01
Prostate_Cancer LDpred1.MultiPRS All.MultiPRS 0.165 0.185 -0.020 3.40e-03 0.155 0.183 -0.028 4.05e-06
Prostate_Cancer LDpred2.PseudoVal All.MultiPRS 0.183 0.185 -0.002 7.52e-01 0.184 0.183 0.001 7.67e-01
Prostate_Cancer SBLUP.Inf All.MultiPRS 0.137 0.185 -0.048 2.53e-12 0.125 0.183 -0.058 6.20e-13
Prostate_Cancer LDpred2.MultiPRS DBSLMM.PseudoVal 0.191 0.179 0.012 8.48e-02 0.183 0.166 0.017 5.57e-06
Prostate_Cancer pT+clump.10FCVal DBSLMM.PseudoVal 0.150 0.179 -0.029 4.34e-16 0.164 0.166 -0.002 7.95e-01
Prostate_Cancer lassosum.10FCVal DBSLMM.PseudoVal 0.182 0.179 0.003 3.03e-01 0.179 0.166 0.014 7.46e-03
Prostate_Cancer All.MultiPRS DBSLMM.PseudoVal 0.185 0.179 0.006 3.80e-01 0.183 0.166 0.018 3.09e-04
Prostate_Cancer LDpred1.MultiPRS DBSLMM.PseudoVal 0.165 0.179 -0.014 4.10e-02 0.155 0.166 -0.010 3.69e-02
Prostate_Cancer LDpred2.PseudoVal DBSLMM.PseudoVal 0.183 0.179 0.004 1.66e-01 0.184 0.166 0.019 5.60e-04
Prostate_Cancer DBSLMM.PseudoVal DBSLMM.PseudoVal 0.179 0.179 0.000 1.00e+00 0.166 0.166 0.000 1.00e+00
Prostate_Cancer LDpred1.Inf DBSLMM.PseudoVal 0.142 0.179 -0.037 2.01e-32 0.133 0.166 -0.032 2.29e-07
Prostate_Cancer LDpred2.Inf DBSLMM.PseudoVal 0.136 0.179 -0.043 9.44e-40 0.126 0.166 -0.039 1.15e-09
Prostate_Cancer lassosum.MultiPRS DBSLMM.PseudoVal 0.188 0.179 0.009 2.05e-01 0.179 0.166 0.014 6.01e-04
Prostate_Cancer LDpred1.10FCVal DBSLMM.PseudoVal 0.159 0.179 -0.020 4.63e-15 0.146 0.166 -0.020 7.65e-05
Prostate_Cancer pT+clump.MultiPRS DBSLMM.PseudoVal 0.165 0.179 -0.014 4.19e-02 0.173 0.166 0.007 1.67e-01
Prostate_Cancer SBayesR.PseudoVal DBSLMM.PseudoVal 0.183 0.179 0.004 8.71e-02 0.182 0.166 0.016 5.23e-04
Prostate_Cancer lassosum.PseudoVal DBSLMM.PseudoVal 0.169 0.179 -0.010 1.71e-03 0.163 0.166 -0.003 6.70e-01
Prostate_Cancer LDpred2.10FCVal DBSLMM.PseudoVal 0.188 0.179 0.009 2.15e-05 0.187 0.166 0.021 7.74e-07
Prostate_Cancer SBLUP.Inf DBSLMM.PseudoVal 0.137 0.179 -0.042 2.36e-39 0.125 0.166 -0.041 3.33e-10
Prostate_Cancer All.MultiPRS lassosum.MultiPRS 0.185 0.188 -0.003 6.95e-01 0.183 0.179 0.004 3.20e-01
Prostate_Cancer LDpred1.MultiPRS lassosum.MultiPRS 0.165 0.188 -0.023 1.15e-17 0.155 0.179 -0.024 6.81e-06
Prostate_Cancer LDpred1.Inf lassosum.MultiPRS 0.142 0.188 -0.046 4.39e-11 0.133 0.179 -0.046 5.20e-11
Prostate_Cancer LDpred2.Inf lassosum.MultiPRS 0.136 0.188 -0.052 9.45e-14 0.126 0.179 -0.053 5.97e-13
Prostate_Cancer lassosum.MultiPRS lassosum.MultiPRS 0.188 0.188 0.000 1.00e+00 0.179 0.179 0.000 1.00e+00
Prostate_Cancer DBSLMM.PseudoVal lassosum.MultiPRS 0.179 0.188 -0.009 2.05e-01 0.166 0.179 -0.014 6.01e-04
Prostate_Cancer lassosum.10FCVal lassosum.MultiPRS 0.182 0.188 -0.006 3.78e-01 0.179 0.179 0.000 9.82e-01
Prostate_Cancer LDpred2.MultiPRS lassosum.MultiPRS 0.191 0.188 0.003 6.54e-01 0.183 0.179 0.004 2.72e-01
Prostate_Cancer pT+clump.10FCVal lassosum.MultiPRS 0.150 0.188 -0.038 4.17e-08 0.164 0.179 -0.016 1.81e-02
Prostate_Cancer lassosum.PseudoVal lassosum.MultiPRS 0.169 0.188 -0.019 6.55e-03 0.163 0.179 -0.017 4.39e-04
Prostate_Cancer LDpred2.10FCVal lassosum.MultiPRS 0.188 0.188 0.001 9.35e-01 0.187 0.179 0.007 3.18e-02
Prostate_Cancer SBayesR.PseudoVal lassosum.MultiPRS 0.183 0.188 -0.005 4.99e-01 0.182 0.179 0.003 5.53e-01
Prostate_Cancer LDpred2.PseudoVal lassosum.MultiPRS 0.183 0.188 -0.005 4.80e-01 0.184 0.179 0.005 2.74e-01
Prostate_Cancer SBLUP.Inf lassosum.MultiPRS 0.137 0.188 -0.051 1.47e-13 0.125 0.179 -0.054 1.74e-13
Prostate_Cancer pT+clump.MultiPRS lassosum.MultiPRS 0.165 0.188 -0.023 9.48e-04 0.173 0.179 -0.007 1.61e-01
Prostate_Cancer LDpred1.10FCVal lassosum.MultiPRS 0.159 0.188 -0.029 3.68e-05 0.146 0.179 -0.034 3.37e-09
Prostate_Cancer All.MultiPRS lassosum.10FCVal 0.185 0.182 0.003 6.23e-01 0.183 0.179 0.004 4.18e-01
Prostate_Cancer LDpred1.MultiPRS lassosum.10FCVal 0.165 0.182 -0.017 1.53e-02 0.155 0.179 -0.024 1.33e-04
Prostate_Cancer LDpred2.PseudoVal lassosum.10FCVal 0.183 0.182 0.001 5.82e-01 0.184 0.179 0.005 2.39e-01
Prostate_Cancer DBSLMM.PseudoVal lassosum.10FCVal 0.179 0.182 -0.003 3.03e-01 0.166 0.179 -0.014 7.46e-03
Prostate_Cancer LDpred1.Inf lassosum.10FCVal 0.142 0.182 -0.040 5.13e-23 0.133 0.179 -0.046 6.92e-09
Prostate_Cancer LDpred2.Inf lassosum.10FCVal 0.136 0.182 -0.046 6.55e-27 0.126 0.179 -0.053 2.07e-10
Prostate_Cancer lassosum.MultiPRS lassosum.10FCVal 0.188 0.182 0.006 3.78e-01 0.179 0.179 0.000 9.82e-01
Prostate_Cancer LDpred1.10FCVal lassosum.10FCVal 0.159 0.182 -0.022 5.59e-11 0.146 0.179 -0.034 6.58e-07
Prostate_Cancer lassosum.10FCVal lassosum.10FCVal 0.182 0.182 0.000 1.00e+00 0.179 0.179 0.000 1.00e+00
Prostate_Cancer LDpred2.MultiPRS lassosum.10FCVal 0.191 0.182 0.009 1.82e-01 0.183 0.179 0.004 3.37e-01
Prostate_Cancer pT+clump.10FCVal lassosum.10FCVal 0.150 0.182 -0.032 1.08e-21 0.164 0.179 -0.016 1.90e-02
Prostate_Cancer lassosum.PseudoVal lassosum.10FCVal 0.169 0.182 -0.013 3.05e-07 0.163 0.179 -0.016 1.02e-03
Prostate_Cancer LDpred2.10FCVal lassosum.10FCVal 0.188 0.182 0.007 1.23e-04 0.187 0.179 0.007 2.94e-02
Prostate_Cancer SBayesR.PseudoVal lassosum.10FCVal 0.183 0.182 0.001 5.40e-01 0.182 0.179 0.003 5.67e-01
Prostate_Cancer SBLUP.Inf lassosum.10FCVal 0.137 0.182 -0.045 1.81e-26 0.125 0.179 -0.054 8.47e-11
Prostate_Cancer pT+clump.MultiPRS lassosum.10FCVal 0.165 0.182 -0.017 1.56e-02 0.173 0.179 -0.007 1.99e-01
Prostate_Cancer All.MultiPRS lassosum.PseudoVal 0.185 0.169 0.016 1.97e-02 0.183 0.163 0.020 4.26e-04
Prostate_Cancer LDpred1.MultiPRS lassosum.PseudoVal 0.165 0.169 -0.004 5.55e-01 0.155 0.163 -0.007 3.52e-01
Prostate_Cancer LDpred1.Inf lassosum.PseudoVal 0.142 0.169 -0.027 1.00e-07 0.133 0.163 -0.030 3.17e-03
Prostate_Cancer LDpred2.Inf lassosum.PseudoVal 0.136 0.169 -0.033 7.79e-10 0.126 0.163 -0.037 5.21e-04
Prostate_Cancer lassosum.MultiPRS lassosum.PseudoVal 0.188 0.169 0.019 6.55e-03 0.179 0.163 0.017 4.39e-04
Prostate_Cancer DBSLMM.PseudoVal lassosum.PseudoVal 0.179 0.169 0.010 1.71e-03 0.166 0.163 0.003 6.70e-01
Prostate_Cancer lassosum.10FCVal lassosum.PseudoVal 0.182 0.169 0.013 3.05e-07 0.179 0.163 0.016 1.02e-03
Prostate_Cancer LDpred2.MultiPRS lassosum.PseudoVal 0.191 0.169 0.022 1.48e-03 0.183 0.163 0.020 7.60e-05
Prostate_Cancer pT+clump.10FCVal lassosum.PseudoVal 0.150 0.169 -0.019 2.55e-11 0.164 0.163 0.001 8.80e-01
Prostate_Cancer lassosum.PseudoVal lassosum.PseudoVal 0.169 0.169 0.000 1.00e+00 0.163 0.163 0.000 1.00e+00
Prostate_Cancer LDpred2.10FCVal lassosum.PseudoVal 0.188 0.169 0.019 3.05e-14 0.187 0.163 0.024 1.97e-06
Prostate_Cancer SBayesR.PseudoVal lassosum.PseudoVal 0.183 0.169 0.014 3.43e-08 0.182 0.163 0.019 1.62e-04
Prostate_Cancer LDpred2.PseudoVal lassosum.PseudoVal 0.183 0.169 0.014 9.26e-09 0.184 0.163 0.022 5.41e-06
Prostate_Cancer SBLUP.Inf lassosum.PseudoVal 0.137 0.169 -0.032 1.52e-09 0.125 0.163 -0.038 3.71e-04
Prostate_Cancer pT+clump.MultiPRS lassosum.PseudoVal 0.165 0.169 -0.004 5.65e-01 0.173 0.163 0.010 1.10e-01
Prostate_Cancer LDpred1.10FCVal lassosum.PseudoVal 0.159 0.169 -0.010 2.66e-02 0.146 0.163 -0.017 4.85e-02
Prostate_Cancer DBSLMM.PseudoVal LDpred1.MultiPRS 0.179 0.165 0.014 4.10e-02 0.166 0.155 0.010 3.69e-02
Prostate_Cancer LDpred2.MultiPRS LDpred1.MultiPRS 0.191 0.165 0.026 1.70e-04 0.183 0.155 0.028 3.06e-07
Prostate_Cancer pT+clump.10FCVal LDpred1.MultiPRS 0.150 0.165 -0.015 3.00e-02 0.164 0.155 0.008 3.30e-01
Prostate_Cancer lassosum.PseudoVal LDpred1.MultiPRS 0.169 0.165 0.004 5.55e-01 0.163 0.155 0.007 3.52e-01
Prostate_Cancer lassosum.10FCVal LDpred1.MultiPRS 0.182 0.165 0.017 1.53e-02 0.179 0.155 0.024 1.33e-04
Prostate_Cancer All.MultiPRS LDpred1.MultiPRS 0.185 0.165 0.020 3.40e-03 0.183 0.155 0.028 4.05e-06
Prostate_Cancer LDpred1.MultiPRS LDpred1.MultiPRS 0.165 0.165 0.000 1.00e+00 0.155 0.155 0.000 1.00e+00
Prostate_Cancer LDpred2.PseudoVal LDpred1.MultiPRS 0.183 0.165 0.018 9.30e-03 0.184 0.155 0.029 3.17e-05
Prostate_Cancer SBLUP.Inf LDpred1.MultiPRS 0.137 0.165 -0.028 4.87e-05 0.125 0.155 -0.030 6.56e-09
Prostate_Cancer LDpred1.Inf LDpred1.MultiPRS 0.142 0.165 -0.023 1.09e-03 0.133 0.155 -0.022 2.17e-07
Prostate_Cancer LDpred2.Inf LDpred1.MultiPRS 0.136 0.165 -0.029 3.76e-05 0.126 0.155 -0.029 2.32e-08
Prostate_Cancer lassosum.MultiPRS LDpred1.MultiPRS 0.188 0.165 0.023 1.15e-17 0.179 0.155 0.024 6.81e-06
Prostate_Cancer LDpred1.10FCVal LDpred1.MultiPRS 0.159 0.165 -0.006 4.20e-01 0.146 0.155 -0.010 1.07e-03
Prostate_Cancer pT+clump.MultiPRS LDpred1.MultiPRS 0.165 0.165 0.000 9.88e-01 0.173 0.155 0.017 7.77e-03
Prostate_Cancer SBayesR.PseudoVal LDpred1.MultiPRS 0.183 0.165 0.018 8.42e-03 0.182 0.155 0.027 2.07e-05
Prostate_Cancer LDpred2.10FCVal LDpred1.MultiPRS 0.188 0.165 0.024 7.06e-04 0.187 0.155 0.031 2.27e-08
Prostate_Cancer All.MultiPRS LDpred1.Inf 0.185 0.142 0.043 5.36e-10 0.183 0.133 0.050 1.00e-10
Prostate_Cancer LDpred1.Inf LDpred1.Inf 0.142 0.142 0.000 1.00e+00 0.133 0.133 0.000 1.00e+00
Prostate_Cancer LDpred2.Inf LDpred1.Inf 0.136 0.142 -0.006 5.84e-05 0.126 0.133 -0.007 1.47e-02
Prostate_Cancer DBSLMM.PseudoVal LDpred1.Inf 0.179 0.142 0.037 2.01e-32 0.166 0.133 0.032 2.29e-07
Prostate_Cancer lassosum.10FCVal LDpred1.Inf 0.182 0.142 0.040 5.13e-23 0.179 0.133 0.046 6.92e-09
Prostate_Cancer LDpred2.MultiPRS LDpred1.Inf 0.191 0.142 0.049 1.61e-12 0.183 0.133 0.050 1.06e-11
Prostate_Cancer pT+clump.10FCVal LDpred1.Inf 0.150 0.142 0.008 1.31e-01 0.164 0.133 0.030 2.23e-03
Prostate_Cancer lassosum.PseudoVal LDpred1.Inf 0.169 0.142 0.027 1.00e-07 0.163 0.133 0.030 3.17e-03
Prostate_Cancer LDpred2.10FCVal LDpred1.Inf 0.188 0.142 0.046 1.46e-33 0.187 0.133 0.053 1.48e-12
Prostate_Cancer SBayesR.PseudoVal LDpred1.Inf 0.183 0.142 0.041 1.16e-23 0.182 0.133 0.049 2.28e-09
Prostate_Cancer LDpred1.MultiPRS LDpred1.Inf 0.165 0.142 0.023 1.09e-03 0.155 0.133 0.022 2.17e-07
Prostate_Cancer LDpred2.PseudoVal LDpred1.Inf 0.183 0.142 0.041 9.73e-20 0.184 0.133 0.051 7.76e-09
Prostate_Cancer SBLUP.Inf LDpred1.Inf 0.137 0.142 -0.006 1.61e-04 0.125 0.133 -0.008 4.82e-03
Prostate_Cancer pT+clump.MultiPRS LDpred1.Inf 0.165 0.142 0.023 1.01e-03 0.173 0.133 0.039 4.34e-07
Prostate_Cancer lassosum.MultiPRS LDpred1.Inf 0.188 0.142 0.046 4.39e-11 0.179 0.133 0.046 5.20e-11
Prostate_Cancer LDpred1.10FCVal LDpred1.Inf 0.159 0.142 0.017 3.49e-44 0.146 0.133 0.012 5.26e-07
Prostate_Cancer LDpred1.Inf LDpred1.10FCVal 0.142 0.159 -0.017 3.49e-44 0.133 0.146 -0.012 5.26e-07
Prostate_Cancer DBSLMM.PseudoVal LDpred1.10FCVal 0.179 0.159 0.020 4.63e-15 0.166 0.146 0.020 7.65e-05
Prostate_Cancer lassosum.10FCVal LDpred1.10FCVal 0.182 0.159 0.022 5.59e-11 0.179 0.146 0.034 6.58e-07
Prostate_Cancer LDpred2.MultiPRS LDpred1.10FCVal 0.191 0.159 0.032 4.43e-06 0.183 0.146 0.037 2.93e-10
Prostate_Cancer pT+clump.10FCVal LDpred1.10FCVal 0.150 0.159 -0.010 3.71e-02 0.164 0.146 0.018 4.74e-02
Prostate_Cancer lassosum.PseudoVal LDpred1.10FCVal 0.169 0.159 0.010 2.66e-02 0.163 0.146 0.017 4.85e-02
Prostate_Cancer LDpred2.10FCVal LDpred1.10FCVal 0.188 0.159 0.029 3.83e-20 0.187 0.146 0.041 3.40e-11
Prostate_Cancer All.MultiPRS LDpred1.10FCVal 0.185 0.159 0.026 1.85e-04 0.183 0.146 0.037 8.28e-09
Prostate_Cancer LDpred1.MultiPRS LDpred1.10FCVal 0.165 0.159 0.006 4.20e-01 0.155 0.146 0.010 1.07e-03
Prostate_Cancer LDpred2.PseudoVal LDpred1.10FCVal 0.183 0.159 0.024 1.29e-09 0.184 0.146 0.039 4.23e-07
Prostate_Cancer SBLUP.Inf LDpred1.10FCVal 0.137 0.159 -0.023 2.49e-30 0.125 0.146 -0.021 1.26e-07
Prostate_Cancer pT+clump.MultiPRS LDpred1.10FCVal 0.165 0.159 0.006 4.11e-01 0.173 0.146 0.027 8.35e-05
Prostate_Cancer LDpred2.Inf LDpred1.10FCVal 0.136 0.159 -0.023 8.45e-31 0.126 0.146 -0.020 6.58e-07
Prostate_Cancer lassosum.MultiPRS LDpred1.10FCVal 0.188 0.159 0.029 3.68e-05 0.179 0.146 0.034 3.37e-09
Prostate_Cancer LDpred1.10FCVal LDpred1.10FCVal 0.159 0.159 0.000 1.00e+00 0.146 0.146 0.000 1.00e+00
Prostate_Cancer SBayesR.PseudoVal LDpred1.10FCVal 0.183 0.159 0.024 4.40e-12 0.182 0.146 0.036 1.02e-07
Prostate_Cancer LDpred2.MultiPRS LDpred2.MultiPRS 0.191 0.191 0.000 1.00e+00 0.183 0.183 0.000 1.00e+00
Prostate_Cancer lassosum.10FCVal LDpred2.MultiPRS 0.182 0.191 -0.009 1.82e-01 0.179 0.183 -0.004 3.37e-01
Prostate_Cancer All.MultiPRS LDpred2.MultiPRS 0.185 0.191 -0.006 4.00e-01 0.183 0.183 0.000 9.78e-01
Prostate_Cancer LDpred1.MultiPRS LDpred2.MultiPRS 0.165 0.191 -0.026 1.70e-04 0.155 0.183 -0.028 3.06e-07
Prostate_Cancer DBSLMM.PseudoVal LDpred2.MultiPRS 0.179 0.191 -0.012 8.48e-02 0.166 0.183 -0.017 5.57e-06
Prostate_Cancer LDpred1.Inf LDpred2.MultiPRS 0.142 0.191 -0.049 1.61e-12 0.133 0.183 -0.050 1.06e-11
Prostate_Cancer LDpred2.Inf LDpred2.MultiPRS 0.136 0.191 -0.055 2.39e-15 0.126 0.183 -0.057 9.19e-14
Prostate_Cancer lassosum.MultiPRS LDpred2.MultiPRS 0.188 0.191 -0.003 6.54e-01 0.179 0.183 -0.004 2.72e-01
Prostate_Cancer LDpred1.10FCVal LDpred2.MultiPRS 0.159 0.191 -0.032 4.43e-06 0.146 0.183 -0.037 2.93e-10
Prostate_Cancer pT+clump.MultiPRS LDpred2.MultiPRS 0.165 0.191 -0.026 1.73e-04 0.173 0.183 -0.010 4.15e-02
Prostate_Cancer SBayesR.PseudoVal LDpred2.MultiPRS 0.183 0.191 -0.008 2.60e-01 0.182 0.183 -0.001 7.39e-01
Prostate_Cancer pT+clump.10FCVal LDpred2.MultiPRS 0.150 0.191 -0.041 2.51e-09 0.164 0.183 -0.019 2.67e-03
Prostate_Cancer lassosum.PseudoVal LDpred2.MultiPRS 0.169 0.191 -0.022 1.48e-03 0.163 0.183 -0.020 7.60e-05
Prostate_Cancer LDpred2.10FCVal LDpred2.MultiPRS 0.188 0.191 -0.003 7.13e-01 0.187 0.183 0.004 6.03e-02
Prostate_Cancer LDpred2.PseudoVal LDpred2.MultiPRS 0.183 0.191 -0.008 2.48e-01 0.184 0.183 0.001 6.57e-01
Prostate_Cancer SBLUP.Inf LDpred2.MultiPRS 0.137 0.191 -0.054 3.83e-15 0.125 0.183 -0.058 5.47e-14
Prostate_Cancer LDpred2.MultiPRS LDpred2.10FCVal 0.191 0.188 0.003 7.13e-01 0.183 0.187 -0.004 6.03e-02
Prostate_Cancer pT+clump.10FCVal LDpred2.10FCVal 0.150 0.188 -0.039 1.72e-34 0.164 0.187 -0.023 2.18e-04
Prostate_Cancer lassosum.10FCVal LDpred2.10FCVal 0.182 0.188 -0.007 1.23e-04 0.179 0.187 -0.007 2.94e-02
Prostate_Cancer All.MultiPRS LDpred2.10FCVal 0.185 0.188 -0.003 6.35e-01 0.183 0.187 -0.004 3.31e-01
Prostate_Cancer LDpred1.MultiPRS LDpred2.10FCVal 0.165 0.188 -0.024 7.06e-04 0.155 0.187 -0.031 2.27e-08
Prostate_Cancer LDpred2.PseudoVal LDpred2.10FCVal 0.183 0.188 -0.005 8.27e-06 0.184 0.187 -0.002 3.47e-01
Prostate_Cancer DBSLMM.PseudoVal LDpred2.10FCVal 0.179 0.188 -0.009 2.15e-05 0.166 0.187 -0.021 7.74e-07
Prostate_Cancer LDpred1.Inf LDpred2.10FCVal 0.142 0.188 -0.046 1.46e-33 0.133 0.187 -0.053 1.48e-12
Prostate_Cancer LDpred2.Inf LDpred2.10FCVal 0.136 0.188 -0.052 1.83e-38 0.126 0.187 -0.060 2.06e-14
Prostate_Cancer lassosum.MultiPRS LDpred2.10FCVal 0.188 0.188 -0.001 9.35e-01 0.179 0.187 -0.007 3.18e-02
Prostate_Cancer LDpred1.10FCVal LDpred2.10FCVal 0.159 0.188 -0.029 3.83e-20 0.146 0.187 -0.041 3.40e-11
Prostate_Cancer pT+clump.MultiPRS LDpred2.10FCVal 0.165 0.188 -0.023 7.22e-04 0.173 0.187 -0.014 5.51e-03
Prostate_Cancer SBayesR.PseudoVal LDpred2.10FCVal 0.183 0.188 -0.005 3.05e-04 0.182 0.187 -0.005 1.21e-01
Prostate_Cancer lassosum.PseudoVal LDpred2.10FCVal 0.169 0.188 -0.019 3.05e-14 0.163 0.187 -0.024 1.97e-06
Prostate_Cancer LDpred2.10FCVal LDpred2.10FCVal 0.188 0.188 0.000 1.00e+00 0.187 0.187 0.000 1.00e+00
Prostate_Cancer SBLUP.Inf LDpred2.10FCVal 0.137 0.188 -0.052 4.26e-37 0.125 0.187 -0.062 1.36e-14
Prostate_Cancer LDpred2.MultiPRS LDpred2.PseudoVal 0.191 0.183 0.008 2.48e-01 0.183 0.184 -0.001 6.57e-01
Prostate_Cancer lassosum.10FCVal LDpred2.PseudoVal 0.182 0.183 -0.001 5.82e-01 0.179 0.184 -0.005 2.39e-01
Prostate_Cancer All.MultiPRS LDpred2.PseudoVal 0.185 0.183 0.002 7.52e-01 0.183 0.184 -0.001 7.67e-01
Prostate_Cancer LDpred1.MultiPRS LDpred2.PseudoVal 0.165 0.183 -0.018 9.30e-03 0.155 0.184 -0.029 3.17e-05
Prostate_Cancer DBSLMM.PseudoVal LDpred2.PseudoVal 0.179 0.183 -0.004 1.66e-01 0.166 0.184 -0.019 5.60e-04
Prostate_Cancer LDpred1.Inf LDpred2.PseudoVal 0.142 0.183 -0.041 9.73e-20 0.133 0.184 -0.051 7.76e-09
Prostate_Cancer LDpred2.Inf LDpred2.PseudoVal 0.136 0.183 -0.047 2.60e-23 0.126 0.184 -0.058 3.14e-10
Prostate_Cancer lassosum.MultiPRS LDpred2.PseudoVal 0.188 0.183 0.005 4.80e-01 0.179 0.184 -0.005 2.74e-01
Prostate_Cancer LDpred1.10FCVal LDpred2.PseudoVal 0.159 0.183 -0.024 1.29e-09 0.146 0.184 -0.039 4.23e-07
Prostate_Cancer pT+clump.MultiPRS LDpred2.PseudoVal 0.165 0.183 -0.018 9.62e-03 0.173 0.184 -0.012 4.06e-02
Prostate_Cancer SBayesR.PseudoVal LDpred2.PseudoVal 0.183 0.183 0.000 8.88e-01 0.182 0.184 -0.002 4.47e-01
Prostate_Cancer pT+clump.10FCVal LDpred2.PseudoVal 0.150 0.183 -0.033 1.79e-28 0.164 0.184 -0.021 4.81e-04
Prostate_Cancer lassosum.PseudoVal LDpred2.PseudoVal 0.169 0.183 -0.014 9.26e-09 0.163 0.184 -0.022 5.41e-06
Prostate_Cancer LDpred2.10FCVal LDpred2.PseudoVal 0.188 0.183 0.005 8.27e-06 0.187 0.184 0.002 3.47e-01
Prostate_Cancer LDpred2.PseudoVal LDpred2.PseudoVal 0.183 0.183 0.000 1.00e+00 0.184 0.184 0.000 1.00e+00
Prostate_Cancer SBLUP.Inf LDpred2.PseudoVal 0.137 0.183 -0.046 1.39e-22 0.125 0.184 -0.059 1.99e-10
Prostate_Cancer DBSLMM.PseudoVal LDpred2.Inf 0.179 0.136 0.043 9.44e-40 0.166 0.126 0.039 1.15e-09
Prostate_Cancer LDpred2.MultiPRS LDpred2.Inf 0.191 0.136 0.055 2.39e-15 0.183 0.126 0.057 9.19e-14
Prostate_Cancer pT+clump.10FCVal LDpred2.Inf 0.150 0.136 0.014 1.00e-02 0.164 0.126 0.038 3.21e-04
Prostate_Cancer lassosum.PseudoVal LDpred2.Inf 0.169 0.136 0.033 7.79e-10 0.163 0.126 0.037 5.21e-04
Prostate_Cancer lassosum.10FCVal LDpred2.Inf 0.182 0.136 0.046 6.55e-27 0.179 0.126 0.053 2.07e-10
Prostate_Cancer All.MultiPRS LDpred2.Inf 0.185 0.136 0.049 1.63e-12 0.183 0.126 0.057 1.65e-12
Prostate_Cancer LDpred1.MultiPRS LDpred2.Inf 0.165 0.136 0.029 3.76e-05 0.155 0.126 0.029 2.32e-08
Prostate_Cancer LDpred2.PseudoVal LDpred2.Inf 0.183 0.136 0.047 2.60e-23 0.184 0.126 0.058 3.14e-10
Prostate_Cancer SBLUP.Inf LDpred2.Inf 0.137 0.136 0.000 4.13e-01 0.125 0.126 -0.001 2.51e-01
Prostate_Cancer LDpred1.Inf LDpred2.Inf 0.142 0.136 0.006 5.84e-05 0.133 0.126 0.007 1.47e-02
Prostate_Cancer LDpred2.Inf LDpred2.Inf 0.136 0.136 0.000 1.00e+00 0.126 0.126 0.000 1.00e+00
Prostate_Cancer lassosum.MultiPRS LDpred2.Inf 0.188 0.136 0.052 9.45e-14 0.179 0.126 0.053 5.97e-13
Prostate_Cancer LDpred1.10FCVal LDpred2.Inf 0.159 0.136 0.023 8.45e-31 0.146 0.126 0.020 6.58e-07
Prostate_Cancer pT+clump.MultiPRS LDpred2.Inf 0.165 0.136 0.029 3.34e-05 0.173 0.126 0.046 1.29e-08
Prostate_Cancer SBayesR.PseudoVal LDpred2.Inf 0.183 0.136 0.047 1.75e-27 0.182 0.126 0.056 7.32e-11
Prostate_Cancer LDpred2.10FCVal LDpred2.Inf 0.188 0.136 0.052 1.83e-38 0.187 0.126 0.060 2.06e-14
Prostate_Cancer All.MultiPRS pT+clump.MultiPRS 0.185 0.165 0.020 3.63e-03 0.183 0.173 0.011 8.22e-02
Prostate_Cancer LDpred1.MultiPRS pT+clump.MultiPRS 0.165 0.165 0.000 9.88e-01 0.155 0.173 -0.017 7.77e-03
Prostate_Cancer LDpred2.PseudoVal pT+clump.MultiPRS 0.183 0.165 0.018 9.62e-03 0.184 0.173 0.012 4.06e-02
Prostate_Cancer DBSLMM.PseudoVal pT+clump.MultiPRS 0.179 0.165 0.014 4.19e-02 0.166 0.173 -0.007 1.67e-01
Prostate_Cancer LDpred1.Inf pT+clump.MultiPRS 0.142 0.165 -0.023 1.01e-03 0.133 0.173 -0.039 4.34e-07
Prostate_Cancer LDpred2.Inf pT+clump.MultiPRS 0.136 0.165 -0.029 3.34e-05 0.126 0.173 -0.046 1.29e-08
Prostate_Cancer lassosum.MultiPRS pT+clump.MultiPRS 0.188 0.165 0.023 9.48e-04 0.179 0.173 0.007 1.61e-01
Prostate_Cancer LDpred1.10FCVal pT+clump.MultiPRS 0.159 0.165 -0.006 4.11e-01 0.146 0.173 -0.027 8.35e-05
Prostate_Cancer lassosum.10FCVal pT+clump.MultiPRS 0.182 0.165 0.017 1.56e-02 0.179 0.173 0.007 1.99e-01
Prostate_Cancer LDpred2.MultiPRS pT+clump.MultiPRS 0.191 0.165 0.026 1.73e-04 0.183 0.173 0.010 4.15e-02
Prostate_Cancer pT+clump.10FCVal pT+clump.MultiPRS 0.150 0.165 -0.015 2.85e-02 0.164 0.173 -0.009 4.81e-02
Prostate_Cancer lassosum.PseudoVal pT+clump.MultiPRS 0.169 0.165 0.004 5.65e-01 0.163 0.173 -0.010 1.10e-01
Prostate_Cancer LDpred2.10FCVal pT+clump.MultiPRS 0.188 0.165 0.023 7.22e-04 0.187 0.173 0.014 5.51e-03
Prostate_Cancer SBayesR.PseudoVal pT+clump.MultiPRS 0.183 0.165 0.018 8.71e-03 0.182 0.173 0.009 8.27e-02
Prostate_Cancer SBLUP.Inf pT+clump.MultiPRS 0.137 0.165 -0.028 4.33e-05 0.125 0.173 -0.048 5.93e-09
Prostate_Cancer pT+clump.MultiPRS pT+clump.MultiPRS 0.165 0.165 0.000 1.00e+00 0.173 0.173 0.000 1.00e+00
Prostate_Cancer lassosum.10FCVal pT+clump.10FCVal 0.182 0.150 0.032 1.08e-21 0.179 0.164 0.016 1.90e-02
Prostate_Cancer All.MultiPRS pT+clump.10FCVal 0.185 0.150 0.035 3.09e-07 0.183 0.164 0.019 7.43e-03
Prostate_Cancer DBSLMM.PseudoVal pT+clump.10FCVal 0.179 0.150 0.029 4.34e-16 0.166 0.164 0.002 7.95e-01
Prostate_Cancer LDpred1.Inf pT+clump.10FCVal 0.142 0.150 -0.008 1.31e-01 0.133 0.164 -0.030 2.23e-03
Prostate_Cancer LDpred2.Inf pT+clump.10FCVal 0.136 0.150 -0.014 1.00e-02 0.126 0.164 -0.038 3.21e-04
Prostate_Cancer lassosum.MultiPRS pT+clump.10FCVal 0.188 0.150 0.038 4.17e-08 0.179 0.164 0.016 1.81e-02
Prostate_Cancer LDpred1.10FCVal pT+clump.10FCVal 0.159 0.150 0.010 3.71e-02 0.146 0.164 -0.018 4.74e-02
Prostate_Cancer pT+clump.MultiPRS pT+clump.10FCVal 0.165 0.150 0.015 2.85e-02 0.173 0.164 0.009 4.81e-02
Prostate_Cancer LDpred2.MultiPRS pT+clump.10FCVal 0.191 0.150 0.041 2.51e-09 0.183 0.164 0.019 2.67e-03
Prostate_Cancer pT+clump.10FCVal pT+clump.10FCVal 0.150 0.150 0.000 1.00e+00 0.164 0.164 0.000 1.00e+00
Prostate_Cancer lassosum.PseudoVal pT+clump.10FCVal 0.169 0.150 0.019 2.55e-11 0.163 0.164 -0.001 8.80e-01
Prostate_Cancer LDpred2.10FCVal pT+clump.10FCVal 0.188 0.150 0.039 1.72e-34 0.187 0.164 0.023 2.18e-04
Prostate_Cancer SBayesR.PseudoVal pT+clump.10FCVal 0.183 0.150 0.033 3.60e-27 0.182 0.164 0.018 3.11e-03
Prostate_Cancer LDpred1.MultiPRS pT+clump.10FCVal 0.165 0.150 0.015 3.00e-02 0.155 0.164 -0.008 3.30e-01
Prostate_Cancer LDpred2.PseudoVal pT+clump.10FCVal 0.183 0.150 0.033 1.79e-28 0.184 0.164 0.021 4.81e-04
Prostate_Cancer SBLUP.Inf pT+clump.10FCVal 0.137 0.150 -0.013 1.31e-02 0.125 0.164 -0.039 2.29e-04
Prostate_Cancer LDpred1.Inf SBayesR.PseudoVal 0.142 0.183 -0.041 1.16e-23 0.133 0.182 -0.049 2.28e-09
Prostate_Cancer DBSLMM.PseudoVal SBayesR.PseudoVal 0.179 0.183 -0.004 8.71e-02 0.166 0.182 -0.016 5.23e-04
Prostate_Cancer lassosum.10FCVal SBayesR.PseudoVal 0.182 0.183 -0.001 5.40e-01 0.179 0.182 -0.003 5.67e-01
Prostate_Cancer LDpred2.MultiPRS SBayesR.PseudoVal 0.191 0.183 0.008 2.60e-01 0.183 0.182 0.001 7.39e-01
Prostate_Cancer pT+clump.10FCVal SBayesR.PseudoVal 0.150 0.183 -0.033 3.60e-27 0.164 0.182 -0.018 3.11e-03
Prostate_Cancer lassosum.PseudoVal SBayesR.PseudoVal 0.169 0.183 -0.014 3.43e-08 0.163 0.182 -0.019 1.62e-04
Prostate_Cancer LDpred2.10FCVal SBayesR.PseudoVal 0.188 0.183 0.005 3.05e-04 0.187 0.182 0.005 1.21e-01
Prostate_Cancer All.MultiPRS SBayesR.PseudoVal 0.185 0.183 0.002 7.76e-01 0.183 0.182 0.001 7.93e-01
Prostate_Cancer LDpred1.MultiPRS SBayesR.PseudoVal 0.165 0.183 -0.018 8.42e-03 0.155 0.182 -0.027 2.07e-05
Prostate_Cancer LDpred2.PseudoVal SBayesR.PseudoVal 0.183 0.183 0.000 8.88e-01 0.184 0.182 0.002 4.47e-01
Prostate_Cancer SBLUP.Inf SBayesR.PseudoVal 0.137 0.183 -0.047 1.29e-26 0.125 0.182 -0.057 4.45e-11
Prostate_Cancer pT+clump.MultiPRS SBayesR.PseudoVal 0.165 0.183 -0.018 8.71e-03 0.173 0.182 -0.009 8.27e-02
Prostate_Cancer LDpred2.Inf SBayesR.PseudoVal 0.136 0.183 -0.047 1.75e-27 0.126 0.182 -0.056 7.32e-11
Prostate_Cancer lassosum.MultiPRS SBayesR.PseudoVal 0.188 0.183 0.005 4.99e-01 0.179 0.182 -0.003 5.53e-01
Prostate_Cancer LDpred1.10FCVal SBayesR.PseudoVal 0.159 0.183 -0.024 4.40e-12 0.146 0.182 -0.036 1.02e-07
Prostate_Cancer SBayesR.PseudoVal SBayesR.PseudoVal 0.183 0.183 0.000 1.00e+00 0.182 0.182 0.000 1.00e+00
Prostate_Cancer All.MultiPRS SBLUP.Inf 0.185 0.137 0.048 2.53e-12 0.183 0.125 0.058 6.20e-13
Prostate_Cancer LDpred1.Inf SBLUP.Inf 0.142 0.137 0.006 1.61e-04 0.133 0.125 0.008 4.82e-03
Prostate_Cancer LDpred2.Inf SBLUP.Inf 0.136 0.137 0.000 4.13e-01 0.126 0.125 0.001 2.51e-01
Prostate_Cancer DBSLMM.PseudoVal SBLUP.Inf 0.179 0.137 0.042 2.36e-39 0.166 0.125 0.041 3.33e-10
Prostate_Cancer lassosum.10FCVal SBLUP.Inf 0.182 0.137 0.045 1.81e-26 0.179 0.125 0.054 8.47e-11
Prostate_Cancer LDpred2.MultiPRS SBLUP.Inf 0.191 0.137 0.054 3.83e-15 0.183 0.125 0.058 5.47e-14
Prostate_Cancer pT+clump.10FCVal SBLUP.Inf 0.150 0.137 0.013 1.31e-02 0.164 0.125 0.039 2.29e-04
Prostate_Cancer lassosum.PseudoVal SBLUP.Inf 0.169 0.137 0.032 1.52e-09 0.163 0.125 0.038 3.71e-04
Prostate_Cancer LDpred2.10FCVal SBLUP.Inf 0.188 0.137 0.052 4.26e-37 0.187 0.125 0.062 1.36e-14
Prostate_Cancer SBayesR.PseudoVal SBLUP.Inf 0.183 0.137 0.047 1.29e-26 0.182 0.125 0.057 4.45e-11
Prostate_Cancer LDpred1.MultiPRS SBLUP.Inf 0.165 0.137 0.028 4.87e-05 0.155 0.125 0.030 6.56e-09
Prostate_Cancer LDpred2.PseudoVal SBLUP.Inf 0.183 0.137 0.046 1.39e-22 0.184 0.125 0.059 1.99e-10
Prostate_Cancer SBLUP.Inf SBLUP.Inf 0.137 0.137 0.000 1.00e+00 0.125 0.125 0.000 1.00e+00
Prostate_Cancer pT+clump.MultiPRS SBLUP.Inf 0.165 0.137 0.028 4.33e-05 0.173 0.125 0.048 5.93e-09
Prostate_Cancer lassosum.MultiPRS SBLUP.Inf 0.188 0.137 0.051 1.47e-13 0.179 0.125 0.054 1.74e-13
Prostate_Cancer LDpred1.10FCVal SBLUP.Inf 0.159 0.137 0.023 2.49e-30 0.146 0.125 0.021 1.26e-07
Breast_Cancer lassosum.PseudoVal All.MultiPRS 0.216 0.229 -0.013 6.37e-02 0.195 0.214 -0.019 6.57e-08
Breast_Cancer All.MultiPRS All.MultiPRS 0.229 0.229 0.000 1.00e+00 0.214 0.214 0.000 1.00e+00
Breast_Cancer DBSLMM.PseudoVal All.MultiPRS 0.216 0.229 -0.013 5.63e-02 0.207 0.214 -0.007 2.81e-02
Breast_Cancer LDpred1.Inf All.MultiPRS 0.172 0.229 -0.057 9.02e-17 0.157 0.214 -0.057 2.35e-16
Breast_Cancer LDpred2.Inf All.MultiPRS 0.168 0.229 -0.061 4.81e-19 0.157 0.214 -0.057 6.95e-16
Breast_Cancer lassosum.MultiPRS All.MultiPRS 0.225 0.229 -0.004 5.09e-01 0.209 0.214 -0.006 9.42e-03
Breast_Cancer LDpred1.10FCVal All.MultiPRS 0.204 0.229 -0.025 2.05e-04 0.188 0.214 -0.026 4.46e-08
Breast_Cancer pT+clump.MultiPRS All.MultiPRS 0.201 0.229 -0.028 5.40e-05 0.186 0.214 -0.028 1.22e-09
Breast_Cancer LDpred2.MultiPRS All.MultiPRS 0.229 0.229 0.000 9.57e-01 0.213 0.214 -0.001 9.90e-02
Breast_Cancer pT+clump.10FCVal All.MultiPRS 0.182 0.229 -0.047 6.64e-12 0.162 0.214 -0.052 3.39e-16
Breast_Cancer lassosum.10FCVal All.MultiPRS 0.218 0.229 -0.011 1.01e-01 0.196 0.214 -0.018 8.76e-08
Breast_Cancer LDpred2.10FCVal All.MultiPRS 0.225 0.229 -0.004 5.30e-01 0.208 0.214 -0.006 2.03e-03
Breast_Cancer SBayesR.PseudoVal All.MultiPRS 0.227 0.229 -0.002 7.16e-01 0.207 0.214 -0.007 5.39e-04
Breast_Cancer LDpred1.MultiPRS All.MultiPRS 0.217 0.229 -0.012 7.84e-02 0.200 0.214 -0.014 5.10e-05
Breast_Cancer LDpred2.PseudoVal All.MultiPRS 0.223 0.229 -0.006 3.81e-01 0.204 0.214 -0.010 6.35e-05
Breast_Cancer SBLUP.Inf All.MultiPRS 0.166 0.229 -0.063 5.68e-20 0.154 0.214 -0.060 8.92e-17
Breast_Cancer LDpred2.MultiPRS DBSLMM.PseudoVal 0.229 0.216 0.013 6.24e-02 0.213 0.207 0.006 8.69e-02
Breast_Cancer pT+clump.10FCVal DBSLMM.PseudoVal 0.182 0.216 -0.034 5.79e-22 0.162 0.207 -0.045 2.95e-10
Breast_Cancer lassosum.PseudoVal DBSLMM.PseudoVal 0.216 0.216 0.000 8.90e-01 0.195 0.207 -0.012 3.72e-02
Breast_Cancer All.MultiPRS DBSLMM.PseudoVal 0.229 0.216 0.013 5.63e-02 0.214 0.207 0.007 2.81e-02
Breast_Cancer LDpred1.MultiPRS DBSLMM.PseudoVal 0.217 0.216 0.001 8.71e-01 0.200 0.207 -0.006 1.28e-01
Breast_Cancer LDpred2.PseudoVal DBSLMM.PseudoVal 0.223 0.216 0.007 2.95e-03 0.204 0.207 -0.003 6.01e-01
Breast_Cancer DBSLMM.PseudoVal DBSLMM.PseudoVal 0.216 0.216 0.000 1.00e+00 0.207 0.207 0.000 1.00e+00
Breast_Cancer LDpred1.Inf DBSLMM.PseudoVal 0.172 0.216 -0.044 3.62e-51 0.157 0.207 -0.049 3.55e-17
Breast_Cancer LDpred2.Inf DBSLMM.PseudoVal 0.168 0.216 -0.048 8.74e-60 0.157 0.207 -0.050 4.40e-17
Breast_Cancer lassosum.MultiPRS DBSLMM.PseudoVal 0.225 0.216 0.009 2.09e-01 0.209 0.207 0.002 6.09e-01
Breast_Cancer LDpred1.10FCVal DBSLMM.PseudoVal 0.204 0.216 -0.012 2.33e-09 0.188 0.207 -0.018 1.38e-05
Breast_Cancer pT+clump.MultiPRS DBSLMM.PseudoVal 0.201 0.216 -0.015 3.22e-02 0.186 0.207 -0.021 1.76e-05
Breast_Cancer SBayesR.PseudoVal DBSLMM.PseudoVal 0.227 0.216 0.011 2.54e-08 0.207 0.207 0.001 8.85e-01
Breast_Cancer lassosum.10FCVal DBSLMM.PseudoVal 0.218 0.216 0.002 4.57e-01 0.196 0.207 -0.010 4.27e-02
Breast_Cancer LDpred2.10FCVal DBSLMM.PseudoVal 0.225 0.216 0.009 6.35e-06 0.208 0.207 0.001 7.19e-01
Breast_Cancer SBLUP.Inf DBSLMM.PseudoVal 0.166 0.216 -0.050 9.50e-64 0.154 0.207 -0.052 1.16e-18
Breast_Cancer All.MultiPRS lassosum.MultiPRS 0.229 0.225 0.004 5.09e-01 0.214 0.209 0.006 9.42e-03
Breast_Cancer LDpred1.MultiPRS lassosum.MultiPRS 0.217 0.225 -0.008 2.70e-01 0.200 0.209 -0.008 2.45e-02
Breast_Cancer LDpred1.Inf lassosum.MultiPRS 0.172 0.225 -0.053 1.74e-14 0.157 0.209 -0.051 5.50e-13
Breast_Cancer LDpred2.Inf lassosum.MultiPRS 0.168 0.225 -0.057 1.28e-16 0.157 0.209 -0.052 1.01e-12
Breast_Cancer lassosum.MultiPRS lassosum.MultiPRS 0.225 0.225 0.000 1.00e+00 0.209 0.209 0.000 1.00e+00
Breast_Cancer DBSLMM.PseudoVal lassosum.MultiPRS 0.216 0.225 -0.009 2.09e-01 0.207 0.209 -0.002 6.09e-01
Breast_Cancer lassosum.PseudoVal lassosum.MultiPRS 0.216 0.225 -0.008 2.30e-01 0.195 0.209 -0.014 2.07e-06
Breast_Cancer LDpred2.MultiPRS lassosum.MultiPRS 0.229 0.225 0.004 5.44e-01 0.213 0.209 0.004 8.58e-02
Breast_Cancer pT+clump.10FCVal lassosum.MultiPRS 0.182 0.225 -0.043 4.67e-10 0.162 0.209 -0.047 2.73e-13
Breast_Cancer lassosum.10FCVal lassosum.MultiPRS 0.218 0.225 -0.007 3.25e-01 0.196 0.209 -0.012 9.44e-07
Breast_Cancer LDpred2.10FCVal lassosum.MultiPRS 0.225 0.225 0.000 9.77e-01 0.208 0.209 -0.001 8.42e-01
Breast_Cancer SBayesR.PseudoVal lassosum.MultiPRS 0.227 0.225 0.002 7.69e-01 0.207 0.209 -0.001 6.53e-01
Breast_Cancer LDpred2.PseudoVal lassosum.MultiPRS 0.223 0.225 -0.002 8.25e-01 0.204 0.209 -0.004 1.87e-01
Breast_Cancer SBLUP.Inf lassosum.MultiPRS 0.166 0.225 -0.059 1.81e-17 0.154 0.209 -0.054 1.05e-13
Breast_Cancer pT+clump.MultiPRS lassosum.MultiPRS 0.201 0.225 -0.023 6.96e-04 0.186 0.209 -0.023 1.70e-06
Breast_Cancer LDpred1.10FCVal lassosum.MultiPRS 0.204 0.225 -0.021 2.20e-03 0.188 0.209 -0.020 4.60e-05
Breast_Cancer All.MultiPRS lassosum.PseudoVal 0.229 0.216 0.013 6.37e-02 0.214 0.195 0.019 6.57e-08
Breast_Cancer LDpred1.MultiPRS lassosum.PseudoVal 0.217 0.216 0.001 9.18e-01 0.200 0.195 0.005 2.89e-01
Breast_Cancer LDpred2.PseudoVal lassosum.PseudoVal 0.223 0.216 0.007 8.20e-04 0.204 0.195 0.009 2.08e-02
Breast_Cancer DBSLMM.PseudoVal lassosum.PseudoVal 0.216 0.216 0.000 8.90e-01 0.207 0.195 0.012 3.72e-02
Breast_Cancer LDpred1.Inf lassosum.PseudoVal 0.172 0.216 -0.045 9.46e-24 0.157 0.195 -0.038 2.40e-05
Breast_Cancer LDpred2.Inf lassosum.PseudoVal 0.168 0.216 -0.049 1.46e-26 0.157 0.195 -0.038 3.28e-05
Breast_Cancer lassosum.MultiPRS lassosum.PseudoVal 0.225 0.216 0.008 2.30e-01 0.209 0.195 0.014 2.07e-06
Breast_Cancer LDpred1.10FCVal lassosum.PseudoVal 0.204 0.216 -0.013 1.46e-04 0.188 0.195 -0.006 3.47e-01
Breast_Cancer lassosum.PseudoVal lassosum.PseudoVal 0.216 0.216 0.000 1.00e+00 0.195 0.195 0.000 1.00e+00
Breast_Cancer LDpred2.MultiPRS lassosum.PseudoVal 0.229 0.216 0.012 7.07e-02 0.213 0.195 0.018 8.28e-07
Breast_Cancer pT+clump.10FCVal lassosum.PseudoVal 0.182 0.216 -0.034 9.09e-31 0.162 0.195 -0.033 2.39e-08
Breast_Cancer lassosum.10FCVal lassosum.PseudoVal 0.218 0.216 0.001 2.48e-01 0.196 0.195 0.001 5.79e-01
Breast_Cancer LDpred2.10FCVal lassosum.PseudoVal 0.225 0.216 0.008 4.36e-05 0.208 0.195 0.013 1.40e-03
Breast_Cancer SBayesR.PseudoVal lassosum.PseudoVal 0.227 0.216 0.010 2.77e-06 0.207 0.195 0.012 4.46e-03
Breast_Cancer SBLUP.Inf lassosum.PseudoVal 0.166 0.216 -0.050 4.71e-28 0.154 0.195 -0.041 1.08e-05
Breast_Cancer pT+clump.MultiPRS lassosum.PseudoVal 0.201 0.216 -0.015 2.77e-02 0.186 0.195 -0.009 9.55e-02
Breast_Cancer All.MultiPRS lassosum.10FCVal 0.229 0.218 0.011 1.01e-01 0.214 0.196 0.018 8.76e-08
Breast_Cancer LDpred1.MultiPRS lassosum.10FCVal 0.217 0.218 -0.001 9.01e-01 0.200 0.196 0.004 3.68e-01
Breast_Cancer LDpred1.Inf lassosum.10FCVal 0.172 0.218 -0.046 4.13e-34 0.157 0.196 -0.039 2.63e-07
Breast_Cancer LDpred2.Inf lassosum.10FCVal 0.168 0.218 -0.050 3.27e-38 0.157 0.196 -0.040 3.89e-07
Breast_Cancer lassosum.MultiPRS lassosum.10FCVal 0.225 0.218 0.007 3.25e-01 0.209 0.196 0.012 9.44e-07
Breast_Cancer DBSLMM.PseudoVal lassosum.10FCVal 0.216 0.218 -0.002 4.57e-01 0.207 0.196 0.010 4.27e-02
Breast_Cancer lassosum.PseudoVal lassosum.10FCVal 0.216 0.218 -0.001 2.48e-01 0.195 0.196 -0.001 5.79e-01
Breast_Cancer LDpred2.MultiPRS lassosum.10FCVal 0.229 0.218 0.011 1.12e-01 0.213 0.196 0.016 1.13e-06
Breast_Cancer pT+clump.10FCVal lassosum.10FCVal 0.182 0.218 -0.036 5.79e-28 0.162 0.196 -0.035 1.38e-07
Breast_Cancer lassosum.10FCVal lassosum.10FCVal 0.218 0.218 0.000 1.00e+00 0.196 0.196 0.000 1.00e+00
Breast_Cancer LDpred2.10FCVal lassosum.10FCVal 0.225 0.218 0.007 1.43e-05 0.208 0.196 0.012 2.81e-04
Breast_Cancer SBayesR.PseudoVal lassosum.10FCVal 0.227 0.218 0.009 9.02e-06 0.207 0.196 0.011 6.08e-03
Breast_Cancer LDpred2.PseudoVal lassosum.10FCVal 0.223 0.218 0.005 2.96e-03 0.204 0.196 0.008 2.84e-02
Breast_Cancer SBLUP.Inf lassosum.10FCVal 0.166 0.218 -0.052 2.51e-40 0.154 0.196 -0.042 8.06e-08
Breast_Cancer pT+clump.MultiPRS lassosum.10FCVal 0.201 0.218 -0.016 1.56e-02 0.186 0.196 -0.010 4.10e-02
Breast_Cancer LDpred1.10FCVal lassosum.10FCVal 0.204 0.218 -0.014 1.77e-07 0.188 0.196 -0.008 1.56e-01
Breast_Cancer DBSLMM.PseudoVal LDpred1.MultiPRS 0.216 0.217 -0.001 8.71e-01 0.207 0.200 0.006 1.28e-01
Breast_Cancer LDpred2.MultiPRS LDpred1.MultiPRS 0.229 0.217 0.012 8.85e-02 0.213 0.200 0.013 3.20e-04
Breast_Cancer pT+clump.10FCVal LDpred1.MultiPRS 0.182 0.217 -0.035 1.07e-07 0.162 0.200 -0.038 2.10e-07
Breast_Cancer lassosum.10FCVal LDpred1.MultiPRS 0.218 0.217 0.001 9.01e-01 0.196 0.200 -0.004 3.68e-01
Breast_Cancer lassosum.PseudoVal LDpred1.MultiPRS 0.216 0.217 -0.001 9.18e-01 0.195 0.200 -0.005 2.89e-01
Breast_Cancer All.MultiPRS LDpred1.MultiPRS 0.229 0.217 0.012 7.84e-02 0.214 0.200 0.014 5.10e-05
Breast_Cancer LDpred1.MultiPRS LDpred1.MultiPRS 0.217 0.217 0.000 1.00e+00 0.200 0.200 0.000 1.00e+00
Breast_Cancer LDpred2.PseudoVal LDpred1.MultiPRS 0.223 0.217 0.006 3.55e-01 0.204 0.200 0.004 3.73e-01
Breast_Cancer SBLUP.Inf LDpred1.MultiPRS 0.166 0.217 -0.051 9.79e-15 0.154 0.200 -0.046 5.07e-12
Breast_Cancer LDpred1.Inf LDpred1.MultiPRS 0.172 0.217 -0.045 6.24e-12 0.157 0.200 -0.043 4.89e-12
Breast_Cancer LDpred2.Inf LDpred1.MultiPRS 0.168 0.217 -0.049 6.52e-14 0.157 0.200 -0.043 4.70e-11
Breast_Cancer lassosum.MultiPRS LDpred1.MultiPRS 0.225 0.217 0.008 2.70e-01 0.209 0.200 0.008 2.45e-02
Breast_Cancer LDpred1.10FCVal LDpred1.MultiPRS 0.204 0.217 -0.013 3.86e-02 0.188 0.200 -0.012 3.80e-04
Breast_Cancer pT+clump.MultiPRS LDpred1.MultiPRS 0.201 0.217 -0.016 2.16e-02 0.186 0.200 -0.014 8.49e-03
Breast_Cancer SBayesR.PseudoVal LDpred1.MultiPRS 0.227 0.217 0.010 1.43e-01 0.207 0.200 0.007 7.69e-02
Breast_Cancer LDpred2.10FCVal LDpred1.MultiPRS 0.225 0.217 0.008 2.34e-01 0.208 0.200 0.008 2.33e-02
Breast_Cancer All.MultiPRS LDpred1.Inf 0.229 0.172 0.057 9.02e-17 0.214 0.157 0.057 2.35e-16
Breast_Cancer LDpred1.Inf LDpred1.Inf 0.172 0.172 0.000 1.00e+00 0.157 0.157 0.000 1.00e+00
Breast_Cancer LDpred2.Inf LDpred1.Inf 0.168 0.172 -0.004 2.55e-04 0.157 0.157 -0.001 7.90e-01
Breast_Cancer DBSLMM.PseudoVal LDpred1.Inf 0.216 0.172 0.044 3.62e-51 0.207 0.157 0.049 3.55e-17
Breast_Cancer lassosum.PseudoVal LDpred1.Inf 0.216 0.172 0.045 9.46e-24 0.195 0.157 0.038 2.40e-05
Breast_Cancer LDpred2.MultiPRS LDpred1.Inf 0.229 0.172 0.057 1.00e-16 0.213 0.157 0.056 1.66e-15
Breast_Cancer pT+clump.10FCVal LDpred1.Inf 0.182 0.172 0.010 3.93e-02 0.162 0.157 0.004 6.51e-01
Breast_Cancer lassosum.10FCVal LDpred1.Inf 0.218 0.172 0.046 4.13e-34 0.196 0.157 0.039 2.63e-07
Breast_Cancer LDpred2.10FCVal LDpred1.Inf 0.225 0.172 0.053 3.32e-61 0.208 0.157 0.051 3.16e-15
Breast_Cancer SBayesR.PseudoVal LDpred1.Inf 0.227 0.172 0.055 4.25e-59 0.207 0.157 0.050 1.96e-13
Breast_Cancer LDpred1.MultiPRS LDpred1.Inf 0.217 0.172 0.045 6.24e-12 0.200 0.157 0.043 4.89e-12
Breast_Cancer LDpred2.PseudoVal LDpred1.Inf 0.223 0.172 0.051 1.64e-43 0.204 0.157 0.047 3.48e-10
Breast_Cancer SBLUP.Inf LDpred1.Inf 0.166 0.172 -0.006 2.88e-07 0.154 0.157 -0.003 1.88e-01
Breast_Cancer pT+clump.MultiPRS LDpred1.Inf 0.201 0.172 0.030 1.78e-05 0.186 0.157 0.029 1.15e-04
Breast_Cancer lassosum.MultiPRS LDpred1.Inf 0.225 0.172 0.053 1.74e-14 0.209 0.157 0.051 5.50e-13
Breast_Cancer LDpred1.10FCVal LDpred1.Inf 0.204 0.172 0.032 1.32e-85 0.188 0.157 0.031 4.63e-22
Breast_Cancer LDpred1.Inf LDpred1.10FCVal 0.172 0.204 -0.032 1.32e-85 0.157 0.188 -0.031 4.63e-22
Breast_Cancer DBSLMM.PseudoVal LDpred1.10FCVal 0.216 0.204 0.012 2.33e-09 0.207 0.188 0.018 1.38e-05
Breast_Cancer lassosum.PseudoVal LDpred1.10FCVal 0.216 0.204 0.013 1.46e-04 0.195 0.188 0.006 3.47e-01
Breast_Cancer LDpred2.MultiPRS LDpred1.10FCVal 0.229 0.204 0.025 2.34e-04 0.213 0.188 0.024 3.11e-07
Breast_Cancer pT+clump.10FCVal LDpred1.10FCVal 0.182 0.204 -0.022 2.43e-07 0.162 0.188 -0.027 1.46e-03
Breast_Cancer lassosum.10FCVal LDpred1.10FCVal 0.218 0.204 0.014 1.77e-07 0.196 0.188 0.008 1.56e-01
Breast_Cancer LDpred2.10FCVal LDpred1.10FCVal 0.225 0.204 0.021 1.60e-23 0.208 0.188 0.019 5.02e-06
Breast_Cancer All.MultiPRS LDpred1.10FCVal 0.229 0.204 0.025 2.05e-04 0.214 0.188 0.026 4.46e-08
Breast_Cancer LDpred1.MultiPRS LDpred1.10FCVal 0.217 0.204 0.013 3.86e-02 0.200 0.188 0.012 3.80e-04
Breast_Cancer LDpred2.PseudoVal LDpred1.10FCVal 0.223 0.204 0.019 6.94e-13 0.204 0.188 0.016 4.54e-03
Breast_Cancer SBLUP.Inf LDpred1.10FCVal 0.166 0.204 -0.038 4.96e-86 0.154 0.188 -0.034 5.88e-19
Breast_Cancer pT+clump.MultiPRS LDpred1.10FCVal 0.201 0.204 -0.002 7.42e-01 0.186 0.188 -0.003 6.72e-01
Breast_Cancer LDpred2.Inf LDpred1.10FCVal 0.168 0.204 -0.036 1.16e-79 0.157 0.188 -0.032 8.91e-17
Breast_Cancer lassosum.MultiPRS LDpred1.10FCVal 0.225 0.204 0.021 2.20e-03 0.209 0.188 0.020 4.60e-05
Breast_Cancer LDpred1.10FCVal LDpred1.10FCVal 0.204 0.204 0.000 1.00e+00 0.188 0.188 0.000 1.00e+00
Breast_Cancer SBayesR.PseudoVal LDpred1.10FCVal 0.227 0.204 0.023 2.36e-22 0.207 0.188 0.019 9.70e-05
Breast_Cancer LDpred2.MultiPRS LDpred2.MultiPRS 0.229 0.229 0.000 1.00e+00 0.213 0.213 0.000 1.00e+00
Breast_Cancer lassosum.PseudoVal LDpred2.MultiPRS 0.216 0.229 -0.012 7.07e-02 0.195 0.213 -0.018 8.28e-07
Breast_Cancer All.MultiPRS LDpred2.MultiPRS 0.229 0.229 0.000 9.57e-01 0.214 0.213 0.001 9.90e-02
Breast_Cancer LDpred1.MultiPRS LDpred2.MultiPRS 0.217 0.229 -0.012 8.85e-02 0.200 0.213 -0.013 3.20e-04
Breast_Cancer DBSLMM.PseudoVal LDpred2.MultiPRS 0.216 0.229 -0.013 6.24e-02 0.207 0.213 -0.006 8.69e-02
Breast_Cancer LDpred1.Inf LDpred2.MultiPRS 0.172 0.229 -0.057 1.00e-16 0.157 0.213 -0.056 1.66e-15
Breast_Cancer LDpred2.Inf LDpred2.MultiPRS 0.168 0.229 -0.061 5.20e-19 0.157 0.213 -0.056 2.85e-15
Breast_Cancer lassosum.MultiPRS LDpred2.MultiPRS 0.225 0.229 -0.004 5.44e-01 0.209 0.213 -0.004 8.58e-02
Breast_Cancer LDpred1.10FCVal LDpred2.MultiPRS 0.204 0.229 -0.025 2.34e-04 0.188 0.213 -0.024 3.11e-07
Breast_Cancer pT+clump.MultiPRS LDpred2.MultiPRS 0.201 0.229 -0.027 6.06e-05 0.186 0.213 -0.027 2.36e-08
Breast_Cancer SBayesR.PseudoVal LDpred2.MultiPRS 0.227 0.229 -0.002 7.55e-01 0.207 0.213 -0.006 1.46e-02
Breast_Cancer pT+clump.10FCVal LDpred2.MultiPRS 0.182 0.229 -0.047 8.40e-12 0.162 0.213 -0.051 4.12e-15
Breast_Cancer lassosum.10FCVal LDpred2.MultiPRS 0.218 0.229 -0.011 1.12e-01 0.196 0.213 -0.016 1.13e-06
Breast_Cancer LDpred2.10FCVal LDpred2.MultiPRS 0.225 0.229 -0.004 5.64e-01 0.208 0.213 -0.005 6.77e-03
Breast_Cancer LDpred2.PseudoVal LDpred2.MultiPRS 0.223 0.229 -0.006 4.09e-01 0.204 0.213 -0.009 2.14e-04
Breast_Cancer SBLUP.Inf LDpred2.MultiPRS 0.166 0.229 -0.063 6.09e-20 0.154 0.213 -0.059 5.14e-16
Breast_Cancer LDpred2.MultiPRS LDpred2.10FCVal 0.229 0.225 0.004 5.64e-01 0.213 0.208 0.005 6.77e-03
Breast_Cancer pT+clump.10FCVal LDpred2.10FCVal 0.182 0.225 -0.043 7.44e-36 0.162 0.208 -0.046 1.88e-11
Breast_Cancer lassosum.PseudoVal LDpred2.10FCVal 0.216 0.225 -0.008 4.36e-05 0.195 0.208 -0.013 1.40e-03
Breast_Cancer All.MultiPRS LDpred2.10FCVal 0.229 0.225 0.004 5.30e-01 0.214 0.208 0.006 2.03e-03
Breast_Cancer LDpred1.MultiPRS LDpred2.10FCVal 0.217 0.225 -0.008 2.34e-01 0.200 0.208 -0.008 2.33e-02
Breast_Cancer LDpred2.PseudoVal LDpred2.10FCVal 0.223 0.225 -0.002 4.61e-02 0.204 0.208 -0.004 2.47e-02
Breast_Cancer DBSLMM.PseudoVal LDpred2.10FCVal 0.216 0.225 -0.009 6.35e-06 0.207 0.208 -0.001 7.19e-01
Breast_Cancer LDpred1.Inf LDpred2.10FCVal 0.172 0.225 -0.053 3.32e-61 0.157 0.208 -0.051 3.16e-15
Breast_Cancer LDpred2.Inf LDpred2.10FCVal 0.168 0.225 -0.057 3.47e-70 0.157 0.208 -0.051 2.35e-15
Breast_Cancer lassosum.MultiPRS LDpred2.10FCVal 0.225 0.225 0.000 9.77e-01 0.209 0.208 0.001 8.42e-01
Breast_Cancer LDpred1.10FCVal LDpred2.10FCVal 0.204 0.225 -0.021 1.60e-23 0.188 0.208 -0.019 5.02e-06
Breast_Cancer pT+clump.MultiPRS LDpred2.10FCVal 0.201 0.225 -0.023 6.03e-04 0.186 0.208 -0.022 1.57e-05
Breast_Cancer SBayesR.PseudoVal LDpred2.10FCVal 0.227 0.225 0.002 1.36e-01 0.207 0.208 -0.001 7.32e-01
Breast_Cancer lassosum.10FCVal LDpred2.10FCVal 0.218 0.225 -0.007 1.43e-05 0.196 0.208 -0.012 2.81e-04
Breast_Cancer LDpred2.10FCVal LDpred2.10FCVal 0.225 0.225 0.000 1.00e+00 0.208 0.208 0.000 1.00e+00
Breast_Cancer SBLUP.Inf LDpred2.10FCVal 0.166 0.225 -0.059 1.74e-71 0.154 0.208 -0.054 4.14e-16
Breast_Cancer LDpred2.MultiPRS LDpred2.PseudoVal 0.229 0.223 0.006 4.09e-01 0.213 0.204 0.009 2.14e-04
Breast_Cancer lassosum.PseudoVal LDpred2.PseudoVal 0.216 0.223 -0.007 8.20e-04 0.195 0.204 -0.009 2.08e-02
Breast_Cancer All.MultiPRS LDpred2.PseudoVal 0.229 0.223 0.006 3.81e-01 0.214 0.204 0.010 6.35e-05
Breast_Cancer LDpred1.MultiPRS LDpred2.PseudoVal 0.217 0.223 -0.006 3.55e-01 0.200 0.204 -0.004 3.73e-01
Breast_Cancer DBSLMM.PseudoVal LDpred2.PseudoVal 0.216 0.223 -0.007 2.95e-03 0.207 0.204 0.003 6.01e-01
Breast_Cancer LDpred1.Inf LDpred2.PseudoVal 0.172 0.223 -0.051 1.64e-43 0.157 0.204 -0.047 3.48e-10
Breast_Cancer LDpred2.Inf LDpred2.PseudoVal 0.168 0.223 -0.055 8.73e-50 0.157 0.204 -0.047 3.08e-10
Breast_Cancer lassosum.MultiPRS LDpred2.PseudoVal 0.225 0.223 0.002 8.25e-01 0.209 0.204 0.004 1.87e-01
Breast_Cancer LDpred1.10FCVal LDpred2.PseudoVal 0.204 0.223 -0.019 6.94e-13 0.188 0.204 -0.016 4.54e-03
Breast_Cancer pT+clump.MultiPRS LDpred2.PseudoVal 0.201 0.223 -0.022 1.46e-03 0.186 0.204 -0.018 9.64e-04
Breast_Cancer SBayesR.PseudoVal LDpred2.PseudoVal 0.227 0.223 0.003 1.38e-02 0.207 0.204 0.003 2.90e-01
Breast_Cancer pT+clump.10FCVal LDpred2.PseudoVal 0.182 0.223 -0.041 3.83e-35 0.162 0.204 -0.042 2.09e-10
Breast_Cancer lassosum.10FCVal LDpred2.PseudoVal 0.218 0.223 -0.005 2.96e-03 0.196 0.204 -0.008 2.84e-02
Breast_Cancer LDpred2.10FCVal LDpred2.PseudoVal 0.225 0.223 0.002 4.61e-02 0.208 0.204 0.004 2.47e-02
Breast_Cancer LDpred2.PseudoVal LDpred2.PseudoVal 0.223 0.223 0.000 1.00e+00 0.204 0.204 0.000 1.00e+00
Breast_Cancer SBLUP.Inf LDpred2.PseudoVal 0.166 0.223 -0.057 2.59e-51 0.154 0.204 -0.050 6.69e-11
Breast_Cancer DBSLMM.PseudoVal LDpred2.Inf 0.216 0.168 0.048 8.74e-60 0.207 0.157 0.050 4.40e-17
Breast_Cancer LDpred2.MultiPRS LDpred2.Inf 0.229 0.168 0.061 5.20e-19 0.213 0.157 0.056 2.85e-15
Breast_Cancer pT+clump.10FCVal LDpred2.Inf 0.182 0.168 0.014 4.86e-03 0.162 0.157 0.005 6.22e-01
Breast_Cancer lassosum.10FCVal LDpred2.Inf 0.218 0.168 0.050 3.27e-38 0.196 0.157 0.040 3.89e-07
Breast_Cancer lassosum.PseudoVal LDpred2.Inf 0.216 0.168 0.049 1.46e-26 0.195 0.157 0.038 3.28e-05
Breast_Cancer All.MultiPRS LDpred2.Inf 0.229 0.168 0.061 4.81e-19 0.214 0.157 0.057 6.95e-16
Breast_Cancer LDpred1.MultiPRS LDpred2.Inf 0.217 0.168 0.049 6.52e-14 0.200 0.157 0.043 4.70e-11
Breast_Cancer LDpred2.PseudoVal LDpred2.Inf 0.223 0.168 0.055 8.73e-50 0.204 0.157 0.047 3.08e-10
Breast_Cancer SBLUP.Inf LDpred2.Inf 0.166 0.168 -0.002 2.58e-03 0.154 0.157 -0.002 2.79e-02
Breast_Cancer LDpred1.Inf LDpred2.Inf 0.172 0.168 0.004 2.55e-04 0.157 0.157 0.001 7.90e-01
Breast_Cancer LDpred2.Inf LDpred2.Inf 0.168 0.168 0.000 1.00e+00 0.157 0.157 0.000 1.00e+00
Breast_Cancer lassosum.MultiPRS LDpred2.Inf 0.225 0.168 0.057 1.28e-16 0.209 0.157 0.052 1.01e-12
Breast_Cancer LDpred1.10FCVal LDpred2.Inf 0.204 0.168 0.036 1.16e-79 0.188 0.157 0.032 8.91e-17
Breast_Cancer pT+clump.MultiPRS LDpred2.Inf 0.201 0.168 0.034 9.84e-07 0.186 0.157 0.029 1.91e-04
Breast_Cancer SBayesR.PseudoVal LDpred2.Inf 0.227 0.168 0.059 1.50e-65 0.207 0.157 0.050 4.23e-13
Breast_Cancer LDpred2.10FCVal LDpred2.Inf 0.225 0.168 0.057 3.47e-70 0.208 0.157 0.051 2.35e-15
Breast_Cancer All.MultiPRS pT+clump.MultiPRS 0.229 0.201 0.028 5.40e-05 0.214 0.186 0.028 1.22e-09
Breast_Cancer LDpred1.MultiPRS pT+clump.MultiPRS 0.217 0.201 0.016 2.16e-02 0.200 0.186 0.014 8.49e-03
Breast_Cancer LDpred2.PseudoVal pT+clump.MultiPRS 0.223 0.201 0.022 1.46e-03 0.204 0.186 0.018 9.64e-04
Breast_Cancer DBSLMM.PseudoVal pT+clump.MultiPRS 0.216 0.201 0.015 3.22e-02 0.207 0.186 0.021 1.76e-05
Breast_Cancer LDpred1.Inf pT+clump.MultiPRS 0.172 0.201 -0.030 1.78e-05 0.157 0.186 -0.029 1.15e-04
Breast_Cancer LDpred2.Inf pT+clump.MultiPRS 0.168 0.201 -0.034 9.84e-07 0.157 0.186 -0.029 1.91e-04
Breast_Cancer lassosum.MultiPRS pT+clump.MultiPRS 0.225 0.201 0.023 6.96e-04 0.209 0.186 0.023 1.70e-06
Breast_Cancer LDpred1.10FCVal pT+clump.MultiPRS 0.204 0.201 0.002 7.42e-01 0.188 0.186 0.003 6.72e-01
Breast_Cancer lassosum.PseudoVal pT+clump.MultiPRS 0.216 0.201 0.015 2.77e-02 0.195 0.186 0.009 9.55e-02
Breast_Cancer LDpred2.MultiPRS pT+clump.MultiPRS 0.229 0.201 0.027 6.06e-05 0.213 0.186 0.027 2.36e-08
Breast_Cancer pT+clump.10FCVal pT+clump.MultiPRS 0.182 0.201 -0.019 4.57e-03 0.162 0.186 -0.024 1.14e-07
Breast_Cancer lassosum.10FCVal pT+clump.MultiPRS 0.218 0.201 0.016 1.56e-02 0.196 0.186 0.010 4.10e-02
Breast_Cancer LDpred2.10FCVal pT+clump.MultiPRS 0.225 0.201 0.023 6.03e-04 0.208 0.186 0.022 1.57e-05
Breast_Cancer SBayesR.PseudoVal pT+clump.MultiPRS 0.227 0.201 0.025 2.17e-04 0.207 0.186 0.021 2.74e-05
Breast_Cancer SBLUP.Inf pT+clump.MultiPRS 0.166 0.201 -0.035 2.92e-07 0.154 0.186 -0.032 4.40e-05
Breast_Cancer pT+clump.MultiPRS pT+clump.MultiPRS 0.201 0.201 0.000 1.00e+00 0.186 0.186 0.000 1.00e+00
Breast_Cancer lassosum.PseudoVal pT+clump.10FCVal 0.216 0.182 0.034 9.09e-31 0.195 0.162 0.033 2.39e-08
Breast_Cancer All.MultiPRS pT+clump.10FCVal 0.229 0.182 0.047 6.64e-12 0.214 0.162 0.052 3.39e-16
Breast_Cancer DBSLMM.PseudoVal pT+clump.10FCVal 0.216 0.182 0.034 5.79e-22 0.207 0.162 0.045 2.95e-10
Breast_Cancer LDpred1.Inf pT+clump.10FCVal 0.172 0.182 -0.010 3.93e-02 0.157 0.162 -0.004 6.51e-01
Breast_Cancer LDpred2.Inf pT+clump.10FCVal 0.168 0.182 -0.014 4.86e-03 0.157 0.162 -0.005 6.22e-01
Breast_Cancer lassosum.MultiPRS pT+clump.10FCVal 0.225 0.182 0.043 4.67e-10 0.209 0.162 0.047 2.73e-13
Breast_Cancer LDpred1.10FCVal pT+clump.10FCVal 0.204 0.182 0.022 2.43e-07 0.188 0.162 0.027 1.46e-03
Breast_Cancer pT+clump.MultiPRS pT+clump.10FCVal 0.201 0.182 0.019 4.57e-03 0.186 0.162 0.024 1.14e-07
Breast_Cancer LDpred2.MultiPRS pT+clump.10FCVal 0.229 0.182 0.047 8.40e-12 0.213 0.162 0.051 4.12e-15
Breast_Cancer pT+clump.10FCVal pT+clump.10FCVal 0.182 0.182 0.000 1.00e+00 0.162 0.162 0.000 1.00e+00
Breast_Cancer lassosum.10FCVal pT+clump.10FCVal 0.218 0.182 0.036 5.79e-28 0.196 0.162 0.035 1.38e-07
Breast_Cancer LDpred2.10FCVal pT+clump.10FCVal 0.225 0.182 0.043 7.44e-36 0.208 0.162 0.046 1.88e-11
Breast_Cancer SBayesR.PseudoVal pT+clump.10FCVal 0.227 0.182 0.045 1.54e-40 0.207 0.162 0.045 1.15e-11
Breast_Cancer LDpred1.MultiPRS pT+clump.10FCVal 0.217 0.182 0.035 1.07e-07 0.200 0.162 0.038 2.10e-07
Breast_Cancer LDpred2.PseudoVal pT+clump.10FCVal 0.223 0.182 0.041 3.83e-35 0.204 0.162 0.042 2.09e-10
Breast_Cancer SBLUP.Inf pT+clump.10FCVal 0.166 0.182 -0.016 1.60e-03 0.154 0.162 -0.007 4.64e-01
Breast_Cancer LDpred1.Inf SBayesR.PseudoVal 0.172 0.227 -0.055 4.25e-59 0.157 0.207 -0.050 1.96e-13
Breast_Cancer DBSLMM.PseudoVal SBayesR.PseudoVal 0.216 0.227 -0.011 2.54e-08 0.207 0.207 -0.001 8.85e-01
Breast_Cancer lassosum.PseudoVal SBayesR.PseudoVal 0.216 0.227 -0.010 2.77e-06 0.195 0.207 -0.012 4.46e-03
Breast_Cancer LDpred2.MultiPRS SBayesR.PseudoVal 0.229 0.227 0.002 7.55e-01 0.213 0.207 0.006 1.46e-02
Breast_Cancer pT+clump.10FCVal SBayesR.PseudoVal 0.182 0.227 -0.045 1.54e-40 0.162 0.207 -0.045 1.15e-11
Breast_Cancer lassosum.10FCVal SBayesR.PseudoVal 0.218 0.227 -0.009 9.02e-06 0.196 0.207 -0.011 6.08e-03
Breast_Cancer LDpred2.10FCVal SBayesR.PseudoVal 0.225 0.227 -0.002 1.36e-01 0.208 0.207 0.001 7.32e-01
Breast_Cancer All.MultiPRS SBayesR.PseudoVal 0.229 0.227 0.002 7.16e-01 0.214 0.207 0.007 5.39e-04
Breast_Cancer LDpred1.MultiPRS SBayesR.PseudoVal 0.217 0.227 -0.010 1.43e-01 0.200 0.207 -0.007 7.69e-02
Breast_Cancer LDpred2.PseudoVal SBayesR.PseudoVal 0.223 0.227 -0.003 1.38e-02 0.204 0.207 -0.003 2.90e-01
Breast_Cancer SBLUP.Inf SBayesR.PseudoVal 0.166 0.227 -0.061 1.17e-67 0.154 0.207 -0.053 5.60e-14
Breast_Cancer pT+clump.MultiPRS SBayesR.PseudoVal 0.201 0.227 -0.025 2.17e-04 0.186 0.207 -0.021 2.74e-05
Breast_Cancer LDpred2.Inf SBayesR.PseudoVal 0.168 0.227 -0.059 1.50e-65 0.157 0.207 -0.050 4.23e-13
Breast_Cancer lassosum.MultiPRS SBayesR.PseudoVal 0.225 0.227 -0.002 7.69e-01 0.209 0.207 0.001 6.53e-01
Breast_Cancer LDpred1.10FCVal SBayesR.PseudoVal 0.204 0.227 -0.023 2.36e-22 0.188 0.207 -0.019 9.70e-05
Breast_Cancer SBayesR.PseudoVal SBayesR.PseudoVal 0.227 0.227 0.000 1.00e+00 0.207 0.207 0.000 1.00e+00
Breast_Cancer All.MultiPRS SBLUP.Inf 0.229 0.166 0.063 5.68e-20 0.214 0.154 0.060 8.92e-17
Breast_Cancer LDpred1.Inf SBLUP.Inf 0.172 0.166 0.006 2.88e-07 0.157 0.154 0.003 1.88e-01
Breast_Cancer LDpred2.Inf SBLUP.Inf 0.168 0.166 0.002 2.58e-03 0.157 0.154 0.002 2.79e-02
Breast_Cancer DBSLMM.PseudoVal SBLUP.Inf 0.216 0.166 0.050 9.50e-64 0.207 0.154 0.052 1.16e-18
Breast_Cancer lassosum.PseudoVal SBLUP.Inf 0.216 0.166 0.050 4.71e-28 0.195 0.154 0.041 1.08e-05
Breast_Cancer LDpred2.MultiPRS SBLUP.Inf 0.229 0.166 0.063 6.09e-20 0.213 0.154 0.059 5.14e-16
Breast_Cancer pT+clump.10FCVal SBLUP.Inf 0.182 0.166 0.016 1.60e-03 0.162 0.154 0.007 4.64e-01
Breast_Cancer lassosum.10FCVal SBLUP.Inf 0.218 0.166 0.052 2.51e-40 0.196 0.154 0.042 8.06e-08
Breast_Cancer LDpred2.10FCVal SBLUP.Inf 0.225 0.166 0.059 1.74e-71 0.208 0.154 0.054 4.14e-16
Breast_Cancer SBayesR.PseudoVal SBLUP.Inf 0.227 0.166 0.061 1.17e-67 0.207 0.154 0.053 5.60e-14
Breast_Cancer LDpred1.MultiPRS SBLUP.Inf 0.217 0.166 0.051 9.79e-15 0.200 0.154 0.046 5.07e-12
Breast_Cancer LDpred2.PseudoVal SBLUP.Inf 0.223 0.166 0.057 2.59e-51 0.204 0.154 0.050 6.69e-11
Breast_Cancer SBLUP.Inf SBLUP.Inf 0.166 0.166 0.000 1.00e+00 0.154 0.154 0.000 1.00e+00
Breast_Cancer pT+clump.MultiPRS SBLUP.Inf 0.201 0.166 0.035 2.92e-07 0.186 0.154 0.032 4.40e-05
Breast_Cancer lassosum.MultiPRS SBLUP.Inf 0.225 0.166 0.059 1.81e-17 0.209 0.154 0.054 1.05e-13
Breast_Cancer LDpred1.10FCVal SBLUP.Inf 0.204 0.166 0.038 4.96e-86 0.188 0.154 0.034 5.88e-19

Show cross-validation differences between methods

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation differences between methods

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation


4.2.2 TEDS

Show cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show TEDS results table

Correlation between PRS model predictions and observed values in TEDS
Phenotype Method Model CrossVal_R CrossVal_R_SE CrossVal_pval IndepVal_R IndepVal_R_SE IndepVal_pval
Height21 All MultiPRS 0.453 0.013 6.83e-220 0.453 0.027 2.22e-56
Height21 DBSLMM PseudoVal 0.418 0.014 1.37e-184 0.437 0.027 4.29e-52
Height21 lassosum MultiPRS 0.439 0.014 1.52e-205 0.445 0.027 3.44e-54
Height21 lassosum 10FCVal 0.436 0.014 7.09e-202 0.442 0.027 1.89e-53
Height21 lassosum PseudoVal 0.355 0.014 1.25e-129 0.351 0.028 4.66e-33
Height21 LDpred1 MultiPRS 0.388 0.014 1.75e-156 0.402 0.028 1.03e-43
Height21 LDpred1 Inf 0.381 0.014 2.24e-150 0.394 0.028 6.70e-42
Height21 LDpred1 10FCVal 0.364 0.014 5.44e-137 0.380 0.028 1.04e-38
Height21 LDpred2 MultiPRS 0.447 0.014 6.63e-214 0.459 0.027 7.83e-58
Height21 LDpred2 10FCVal 0.447 0.014 8.32e-214 0.453 0.027 3.19e-56
Height21 LDpred2 PseudoVal 0.432 0.014 2.85e-198 0.446 0.027 2.43e-54
Height21 LDpred2 Inf 0.388 0.014 7.57e-157 0.400 0.028 3.63e-43
Height21 pT+clump MultiPRS 0.403 0.014 3.92e-170 0.396 0.028 2.65e-42
Height21 pT+clump 10FCVal 0.388 0.014 6.69e-157 0.353 0.028 2.30e-33
Height21 SBayesR PseudoVal 0.434 0.014 3.34e-200 0.467 0.027 4.48e-60
Height21 SBLUP Inf 0.381 0.014 7.17e-151 0.392 0.028 1.87e-41
BMI21 All MultiPRS 0.378 0.014 2.63e-142 0.346 0.029 8.61e-31
BMI21 DBSLMM PseudoVal 0.357 0.014 9.10e-126 0.320 0.029 2.64e-26
BMI21 lassosum MultiPRS 0.365 0.014 5.66e-132 0.337 0.029 3.64e-29
BMI21 lassosum 10FCVal 0.359 0.014 3.67e-127 0.333 0.029 2.02e-28
BMI21 lassosum PseudoVal 0.284 0.015 4.71e-78 0.229 0.030 7.65e-14
BMI21 LDpred1 MultiPRS 0.348 0.015 1.92e-119 0.320 0.029 2.92e-26
BMI21 LDpred1 Inf 0.346 0.015 1.84e-117 0.316 0.029 1.31e-25
BMI21 LDpred1 10FCVal 0.336 0.015 1.51e-110 0.313 0.029 3.78e-25
BMI21 LDpred2 MultiPRS 0.377 0.014 2.33e-141 0.342 0.029 4.72e-30
BMI21 LDpred2 10FCVal 0.377 0.014 3.20e-141 0.336 0.029 5.51e-29
BMI21 LDpred2 PseudoVal 0.378 0.014 7.56e-142 0.348 0.029 3.72e-31
BMI21 LDpred2 Inf 0.350 0.014 7.86e-121 0.319 0.029 3.98e-26
BMI21 pT+clump MultiPRS 0.320 0.015 3.18e-100 0.283 0.030 1.11e-20
BMI21 pT+clump 10FCVal 0.312 0.015 3.06e-95 0.285 0.030 6.78e-21
BMI21 SBayesR PseudoVal 0.373 0.014 1.25e-137 0.338 0.029 2.75e-29
BMI21 SBLUP Inf 0.347 0.015 1.29e-118 0.311 0.029 8.83e-25
GCSE All MultiPRS 0.423 0.012 1.55e-252 0.355 0.024 1.13e-44
GCSE DBSLMM PseudoVal 0.402 0.012 4.19e-226 0.339 0.025 1.59e-40
GCSE lassosum MultiPRS 0.412 0.012 1.52e-237 0.357 0.024 3.63e-45
GCSE lassosum 10FCVal 0.410 0.012 1.01e-235 0.355 0.024 1.23e-44
GCSE lassosum PseudoVal 0.316 0.012 2.47e-135 0.273 0.025 2.65e-26
GCSE LDpred1 MultiPRS 0.414 0.012 5.57e-240 0.341 0.025 4.01e-41
GCSE LDpred1 Inf 0.409 0.012 1.48e-234 0.337 0.025 5.22e-40
GCSE LDpred1 10FCVal 0.405 0.012 9.03e-230 0.337 0.025 4.32e-40
GCSE LDpred2 MultiPRS 0.423 0.012 1.03e-252 0.356 0.024 6.26e-45
GCSE LDpred2 10FCVal 0.423 0.012 1.89e-251 0.358 0.024 1.82e-45
GCSE LDpred2 PseudoVal 0.422 0.012 7.71e-251 0.358 0.024 2.17e-45
GCSE LDpred2 Inf 0.413 0.012 8.70e-240 0.343 0.025 1.66e-41
GCSE pT+clump MultiPRS 0.382 0.012 1.35e-201 0.330 0.025 2.04e-38
GCSE pT+clump 10FCVal 0.374 0.012 4.00e-193 0.315 0.025 4.83e-35
GCSE SBayesR PseudoVal 0.420 0.012 5.56e-248 0.350 0.025 2.67e-43
GCSE SBLUP Inf 0.412 0.012 1.25e-237 0.344 0.025 6.57e-42
ADHD All MultiPRS 0.118 0.013 7.28e-21 0.182 0.025 3.45e-13
ADHD DBSLMM PseudoVal 0.110 0.013 1.60e-18 0.174 0.025 3.99e-12
ADHD lassosum MultiPRS 0.117 0.013 9.18e-21 0.190 0.025 2.42e-14
ADHD lassosum PseudoVal 0.080 0.013 2.23e-10 0.108 0.025 1.79e-05
ADHD lassosum 10FCVal 0.115 0.013 5.35e-20 0.186 0.025 1.03e-13
ADHD LDpred1 MultiPRS 0.113 0.013 1.87e-19 0.190 0.025 2.86e-14
ADHD LDpred1 Inf 0.111 0.013 7.76e-19 0.188 0.025 5.50e-14
ADHD LDpred1 10FCVal 0.114 0.013 1.02e-19 0.190 0.025 2.77e-14
ADHD LDpred2 MultiPRS 0.113 0.013 2.67e-19 0.190 0.025 3.07e-14
ADHD LDpred2 10FCVal 0.117 0.013 1.58e-20 0.187 0.025 7.27e-14
ADHD LDpred2 PseudoVal 0.114 0.013 9.02e-20 0.190 0.025 2.71e-14
ADHD LDpred2 Inf 0.113 0.013 2.76e-19 0.189 0.025 4.07e-14
ADHD pT+clump MultiPRS 0.093 0.013 1.13e-13 0.151 0.025 1.91e-09
ADHD pT+clump 10FCVal 0.092 0.013 1.89e-13 0.144 0.025 9.71e-09
ADHD SBayesR PseudoVal 0.111 0.013 6.80e-19 0.189 0.025 4.37e-14
ADHD SBLUP Inf 0.112 0.013 3.85e-19 0.188 0.025 5.20e-14

Show cross-validation results compared to pT+clump

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results compared to pT+clump

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show difference results table

Difference between methods in TEDS with UKB reference
Phenotype Model 1 Test Model 2 Test Model 1 CrossVal R Model 2 CrossVal R CrossVal R Diff CrossVal R Diff P Model 1 IndepVal R Model 2 IndepVal R IndepVal R Diff IndepVal R Diff P
Height21 lassosum.10FCVal All.MultiPRS 0.436 0.453 -0.017 3.39e-01 0.442 0.453 -0.011 1.50e-01
Height21 All.MultiPRS All.MultiPRS 0.453 0.453 0.000 1.00e+00 0.453 0.453 0.000 1.00e+00
Height21 DBSLMM.PseudoVal All.MultiPRS 0.418 0.453 -0.035 5.46e-02 0.437 0.453 -0.016 1.22e-01
Height21 LDpred1.Inf All.MultiPRS 0.381 0.453 -0.073 7.71e-05 0.394 0.453 -0.059 8.51e-05
Height21 LDpred2.Inf All.MultiPRS 0.388 0.453 -0.065 3.71e-04 0.400 0.453 -0.053 2.35e-04
Height21 lassosum.MultiPRS All.MultiPRS 0.439 0.453 -0.014 9.80e-05 0.445 0.453 -0.008 2.33e-01
Height21 LDpred1.10FCVal All.MultiPRS 0.364 0.453 -0.089 1.49e-06 0.380 0.453 -0.074 3.88e-06
Height21 pT+clump.MultiPRS All.MultiPRS 0.403 0.453 -0.050 6.57e-03 0.396 0.453 -0.057 1.00e-06
Height21 LDpred2.MultiPRS All.MultiPRS 0.447 0.453 -0.006 7.53e-01 0.459 0.453 0.005 2.31e-01
Height21 pT+clump.10FCVal All.MultiPRS 0.388 0.453 -0.065 3.99e-04 0.353 0.453 -0.100 1.16e-11
Height21 lassosum.PseudoVal All.MultiPRS 0.355 0.453 -0.098 9.99e-08 0.351 0.453 -0.102 7.91e-09
Height21 LDpred2.10FCVal All.MultiPRS 0.447 0.453 -0.006 7.50e-01 0.453 0.453 -0.001 9.12e-01
Height21 SBayesR.PseudoVal All.MultiPRS 0.434 0.453 -0.019 2.94e-01 0.467 0.453 0.013 7.74e-02
Height21 LDpred1.MultiPRS All.MultiPRS 0.388 0.453 -0.065 3.65e-04 0.402 0.453 -0.051 2.08e-04
Height21 LDpred2.PseudoVal All.MultiPRS 0.432 0.453 -0.021 2.49e-01 0.446 0.453 -0.008 3.84e-01
Height21 SBLUP.Inf All.MultiPRS 0.381 0.453 -0.072 8.46e-05 0.392 0.453 -0.061 4.66e-05
Height21 LDpred2.MultiPRS DBSLMM.PseudoVal 0.447 0.418 0.029 1.05e-01 0.459 0.437 0.022 4.70e-02
Height21 pT+clump.10FCVal DBSLMM.PseudoVal 0.388 0.418 -0.030 1.21e-03 0.353 0.437 -0.084 5.41e-06
Height21 lassosum.10FCVal DBSLMM.PseudoVal 0.436 0.418 0.017 5.51e-03 0.442 0.437 0.005 6.64e-01
Height21 All.MultiPRS DBSLMM.PseudoVal 0.453 0.418 0.035 5.46e-02 0.453 0.437 0.016 1.22e-01
Height21 LDpred1.MultiPRS DBSLMM.PseudoVal 0.388 0.418 -0.031 9.84e-02 0.402 0.437 -0.035 4.38e-03
Height21 LDpred2.PseudoVal DBSLMM.PseudoVal 0.432 0.418 0.014 6.57e-03 0.446 0.437 0.009 4.07e-01
Height21 DBSLMM.PseudoVal DBSLMM.PseudoVal 0.418 0.418 0.000 1.00e+00 0.437 0.437 0.000 1.00e+00
Height21 LDpred1.Inf DBSLMM.PseudoVal 0.381 0.418 -0.038 4.65e-10 0.394 0.437 -0.043 5.00e-04
Height21 LDpred2.Inf DBSLMM.PseudoVal 0.388 0.418 -0.030 2.22e-07 0.400 0.437 -0.037 2.24e-03
Height21 lassosum.MultiPRS DBSLMM.PseudoVal 0.439 0.418 0.021 2.46e-01 0.445 0.437 0.008 4.31e-01
Height21 LDpred1.10FCVal DBSLMM.PseudoVal 0.364 0.418 -0.054 4.24e-15 0.380 0.437 -0.057 3.78e-05
Height21 pT+clump.MultiPRS DBSLMM.PseudoVal 0.403 0.418 -0.015 4.03e-01 0.396 0.437 -0.041 1.99e-03
Height21 SBayesR.PseudoVal DBSLMM.PseudoVal 0.434 0.418 0.016 6.40e-04 0.467 0.437 0.030 1.23e-03
Height21 lassosum.PseudoVal DBSLMM.PseudoVal 0.355 0.418 -0.064 7.07e-09 0.351 0.437 -0.086 4.07e-05
Height21 LDpred2.10FCVal DBSLMM.PseudoVal 0.447 0.418 0.029 1.75e-07 0.453 0.437 0.016 1.56e-01
Height21 SBLUP.Inf DBSLMM.PseudoVal 0.381 0.418 -0.037 2.01e-10 0.392 0.437 -0.045 2.25e-04
Height21 All.MultiPRS lassosum.MultiPRS 0.453 0.439 0.014 9.80e-05 0.453 0.445 0.008 2.33e-01
Height21 LDpred1.MultiPRS lassosum.MultiPRS 0.388 0.439 -0.052 5.01e-03 0.402 0.445 -0.043 2.81e-03
Height21 LDpred1.Inf lassosum.MultiPRS 0.381 0.439 -0.059 1.43e-03 0.394 0.445 -0.051 7.45e-04
Height21 LDpred2.Inf lassosum.MultiPRS 0.388 0.439 -0.051 5.20e-03 0.400 0.445 -0.045 2.37e-03
Height21 lassosum.MultiPRS lassosum.MultiPRS 0.439 0.439 0.000 1.00e+00 0.445 0.445 0.000 1.00e+00
Height21 DBSLMM.PseudoVal lassosum.MultiPRS 0.418 0.439 -0.021 2.46e-01 0.437 0.445 -0.008 4.31e-01
Height21 lassosum.10FCVal lassosum.MultiPRS 0.436 0.439 -0.004 8.43e-01 0.442 0.445 -0.003 4.62e-01
Height21 LDpred2.MultiPRS lassosum.MultiPRS 0.447 0.439 0.008 6.55e-01 0.459 0.445 0.014 1.37e-01
Height21 pT+clump.10FCVal lassosum.MultiPRS 0.388 0.439 -0.051 5.34e-03 0.353 0.445 -0.092 1.61e-08
Height21 lassosum.PseudoVal lassosum.MultiPRS 0.355 0.439 -0.085 5.03e-06 0.351 0.445 -0.094 2.85e-09
Height21 LDpred2.10FCVal lassosum.MultiPRS 0.447 0.439 0.008 6.60e-01 0.453 0.445 0.008 3.94e-01
Height21 SBayesR.PseudoVal lassosum.MultiPRS 0.434 0.439 -0.005 7.72e-01 0.467 0.445 0.022 2.36e-02
Height21 LDpred2.PseudoVal lassosum.MultiPRS 0.432 0.439 -0.007 6.93e-01 0.446 0.445 0.001 9.59e-01
Height21 SBLUP.Inf lassosum.MultiPRS 0.381 0.439 -0.058 1.55e-03 0.392 0.445 -0.053 5.17e-04
Height21 pT+clump.MultiPRS lassosum.MultiPRS 0.403 0.439 -0.036 4.94e-02 0.396 0.445 -0.049 1.27e-04
Height21 LDpred1.10FCVal lassosum.MultiPRS 0.364 0.439 -0.075 5.16e-05 0.380 0.445 -0.066 5.42e-05
Height21 All.MultiPRS lassosum.10FCVal 0.453 0.436 0.017 3.39e-01 0.453 0.442 0.011 1.50e-01
Height21 LDpred1.MultiPRS lassosum.10FCVal 0.388 0.436 -0.048 8.94e-03 0.402 0.442 -0.040 1.35e-02
Height21 LDpred2.PseudoVal lassosum.10FCVal 0.432 0.436 -0.004 5.72e-01 0.446 0.442 0.003 7.87e-01
Height21 DBSLMM.PseudoVal lassosum.10FCVal 0.418 0.436 -0.017 5.51e-03 0.437 0.442 -0.005 6.64e-01
Height21 LDpred1.Inf lassosum.10FCVal 0.381 0.436 -0.055 1.70e-10 0.394 0.442 -0.048 4.92e-03
Height21 LDpred2.Inf lassosum.10FCVal 0.388 0.436 -0.048 1.61e-08 0.400 0.442 -0.042 1.21e-02
Height21 lassosum.MultiPRS lassosum.10FCVal 0.439 0.436 0.004 8.43e-01 0.445 0.442 0.003 4.62e-01
Height21 LDpred1.10FCVal lassosum.10FCVal 0.364 0.436 -0.072 7.42e-15 0.380 0.442 -0.063 5.25e-04
Height21 lassosum.10FCVal lassosum.10FCVal 0.436 0.436 0.000 1.00e+00 0.442 0.442 0.000 1.00e+00
Height21 LDpred2.MultiPRS lassosum.10FCVal 0.447 0.436 0.012 5.16e-01 0.459 0.442 0.016 9.35e-02
Height21 pT+clump.10FCVal lassosum.10FCVal 0.388 0.436 -0.048 1.06e-08 0.353 0.442 -0.089 3.47e-08
Height21 lassosum.PseudoVal lassosum.10FCVal 0.355 0.436 -0.081 1.11e-23 0.351 0.442 -0.091 5.83e-09
Height21 LDpred2.10FCVal lassosum.10FCVal 0.447 0.436 0.011 1.35e-02 0.453 0.442 0.010 2.63e-01
Height21 SBayesR.PseudoVal lassosum.10FCVal 0.434 0.436 -0.002 7.63e-01 0.467 0.442 0.024 2.28e-02
Height21 SBLUP.Inf lassosum.10FCVal 0.381 0.436 -0.055 2.42e-10 0.392 0.442 -0.050 3.74e-03
Height21 pT+clump.MultiPRS lassosum.10FCVal 0.403 0.436 -0.033 7.29e-02 0.396 0.442 -0.046 4.49e-04
Height21 All.MultiPRS lassosum.PseudoVal 0.453 0.355 0.098 9.99e-08 0.453 0.351 0.102 7.91e-09
Height21 LDpred1.MultiPRS lassosum.PseudoVal 0.388 0.355 0.033 8.38e-02 0.402 0.351 0.051 4.25e-02
Height21 LDpred1.Inf lassosum.PseudoVal 0.381 0.355 0.026 5.60e-02 0.394 0.351 0.043 9.92e-02
Height21 LDpred2.Inf lassosum.PseudoVal 0.388 0.355 0.033 1.23e-02 0.400 0.351 0.049 5.98e-02
Height21 lassosum.MultiPRS lassosum.PseudoVal 0.439 0.355 0.085 5.03e-06 0.445 0.351 0.094 2.85e-09
Height21 DBSLMM.PseudoVal lassosum.PseudoVal 0.418 0.355 0.064 7.07e-09 0.437 0.351 0.086 4.07e-05
Height21 lassosum.10FCVal lassosum.PseudoVal 0.436 0.355 0.081 1.11e-23 0.442 0.351 0.091 5.83e-09
Height21 LDpred2.MultiPRS lassosum.PseudoVal 0.447 0.355 0.093 5.19e-07 0.459 0.351 0.107 1.61e-07
Height21 pT+clump.10FCVal lassosum.PseudoVal 0.388 0.355 0.033 1.74e-03 0.353 0.351 0.002 9.38e-01
Height21 lassosum.PseudoVal lassosum.PseudoVal 0.355 0.355 0.000 1.00e+00 0.351 0.351 0.000 1.00e+00
Height21 LDpred2.10FCVal lassosum.PseudoVal 0.447 0.355 0.093 1.24e-18 0.453 0.351 0.101 7.30e-07
Height21 SBayesR.PseudoVal lassosum.PseudoVal 0.434 0.355 0.079 8.89e-13 0.467 0.351 0.115 6.48e-08
Height21 LDpred2.PseudoVal lassosum.PseudoVal 0.432 0.355 0.078 8.78e-11 0.446 0.351 0.094 5.16e-05
Height21 SBLUP.Inf lassosum.PseudoVal 0.381 0.355 0.026 5.17e-02 0.392 0.351 0.041 1.20e-01
Height21 pT+clump.MultiPRS lassosum.PseudoVal 0.403 0.355 0.048 1.08e-02 0.396 0.351 0.045 2.81e-02
Height21 LDpred1.10FCVal lassosum.PseudoVal 0.364 0.355 0.009 4.97e-01 0.380 0.351 0.028 2.88e-01
Height21 DBSLMM.PseudoVal LDpred1.MultiPRS 0.418 0.388 0.031 9.84e-02 0.437 0.402 0.035 4.38e-03
Height21 LDpred2.MultiPRS LDpred1.MultiPRS 0.447 0.388 0.060 9.89e-04 0.459 0.402 0.056 1.20e-05
Height21 pT+clump.10FCVal LDpred1.MultiPRS 0.388 0.388 0.000 9.80e-01 0.353 0.402 -0.049 2.96e-02
Height21 lassosum.PseudoVal LDpred1.MultiPRS 0.355 0.388 -0.033 8.38e-02 0.351 0.402 -0.051 4.25e-02
Height21 lassosum.10FCVal LDpred1.MultiPRS 0.436 0.388 0.048 8.94e-03 0.442 0.402 0.040 1.35e-02
Height21 All.MultiPRS LDpred1.MultiPRS 0.453 0.388 0.065 3.65e-04 0.453 0.402 0.051 2.08e-04
Height21 LDpred1.MultiPRS LDpred1.MultiPRS 0.388 0.388 0.000 1.00e+00 0.402 0.402 0.000 1.00e+00
Height21 LDpred2.PseudoVal LDpred1.MultiPRS 0.432 0.388 0.045 1.56e-02 0.446 0.402 0.043 9.52e-06
Height21 SBLUP.Inf LDpred1.MultiPRS 0.381 0.388 -0.007 7.28e-01 0.392 0.402 -0.010 1.81e-01
Height21 LDpred1.Inf LDpred1.MultiPRS 0.381 0.388 -0.007 7.05e-01 0.394 0.402 -0.008 2.10e-01
Height21 LDpred2.Inf LDpred1.MultiPRS 0.388 0.388 0.000 9.82e-01 0.400 0.402 -0.002 7.52e-01
Height21 lassosum.MultiPRS LDpred1.MultiPRS 0.439 0.388 0.052 5.01e-03 0.445 0.402 0.043 2.81e-03
Height21 LDpred1.10FCVal LDpred1.MultiPRS 0.364 0.388 -0.023 2.18e-01 0.380 0.402 -0.023 1.18e-02
Height21 pT+clump.MultiPRS LDpred1.MultiPRS 0.403 0.388 0.015 4.13e-01 0.396 0.402 -0.006 7.18e-01
Height21 SBayesR.PseudoVal LDpred1.MultiPRS 0.434 0.388 0.047 1.17e-02 0.467 0.402 0.064 3.18e-09
Height21 LDpred2.10FCVal LDpred1.MultiPRS 0.447 0.388 0.060 1.14e-03 0.453 0.402 0.050 1.33e-04
Height21 All.MultiPRS LDpred1.Inf 0.453 0.381 0.073 7.71e-05 0.453 0.394 0.059 8.51e-05
Height21 LDpred1.Inf LDpred1.Inf 0.381 0.381 0.000 1.00e+00 0.394 0.394 0.000 1.00e+00
Height21 LDpred2.Inf LDpred1.Inf 0.388 0.381 0.008 2.82e-03 0.400 0.394 0.006 2.74e-01
Height21 DBSLMM.PseudoVal LDpred1.Inf 0.418 0.381 0.038 4.65e-10 0.437 0.394 0.043 5.00e-04
Height21 lassosum.10FCVal LDpred1.Inf 0.436 0.381 0.055 1.70e-10 0.442 0.394 0.048 4.92e-03
Height21 LDpred2.MultiPRS LDpred1.Inf 0.447 0.381 0.067 2.43e-04 0.459 0.394 0.064 3.44e-06
Height21 pT+clump.10FCVal LDpred1.Inf 0.388 0.381 0.008 5.09e-01 0.353 0.394 -0.041 7.59e-02
Height21 lassosum.PseudoVal LDpred1.Inf 0.355 0.381 -0.026 5.60e-02 0.351 0.394 -0.043 9.92e-02
Height21 LDpred2.10FCVal LDpred1.Inf 0.447 0.381 0.067 1.08e-20 0.453 0.394 0.058 4.17e-05
Height21 SBayesR.PseudoVal LDpred1.Inf 0.434 0.381 0.054 2.43e-20 0.467 0.394 0.072 3.56e-10
Height21 LDpred1.MultiPRS LDpred1.Inf 0.388 0.381 0.007 7.05e-01 0.402 0.394 0.008 2.10e-01
Height21 LDpred2.PseudoVal LDpred1.Inf 0.432 0.381 0.052 2.30e-23 0.446 0.394 0.051 7.51e-07
Height21 SBLUP.Inf LDpred1.Inf 0.381 0.381 0.001 8.25e-01 0.392 0.394 -0.002 6.94e-01
Height21 pT+clump.MultiPRS LDpred1.Inf 0.403 0.381 0.023 2.29e-01 0.396 0.394 0.002 9.18e-01
Height21 lassosum.MultiPRS LDpred1.Inf 0.439 0.381 0.059 1.43e-03 0.445 0.394 0.051 7.45e-04
Height21 LDpred1.10FCVal LDpred1.Inf 0.364 0.381 -0.016 1.21e-04 0.380 0.394 -0.015 7.66e-02
Height21 LDpred1.Inf LDpred1.10FCVal 0.381 0.364 0.016 1.21e-04 0.394 0.380 0.015 7.66e-02
Height21 DBSLMM.PseudoVal LDpred1.10FCVal 0.418 0.364 0.054 4.24e-15 0.437 0.380 0.057 3.78e-05
Height21 lassosum.10FCVal LDpred1.10FCVal 0.436 0.364 0.072 7.42e-15 0.442 0.380 0.063 5.25e-04
Height21 LDpred2.MultiPRS LDpred1.10FCVal 0.447 0.364 0.083 5.74e-06 0.459 0.380 0.079 9.10e-08
Height21 pT+clump.10FCVal LDpred1.10FCVal 0.388 0.364 0.024 4.79e-02 0.353 0.380 -0.027 2.73e-01
Height21 lassosum.PseudoVal LDpred1.10FCVal 0.355 0.364 -0.009 4.97e-01 0.351 0.380 -0.028 2.88e-01
Height21 LDpred2.10FCVal LDpred1.10FCVal 0.447 0.364 0.083 2.11e-26 0.453 0.380 0.073 1.50e-06
Height21 All.MultiPRS LDpred1.10FCVal 0.453 0.364 0.089 1.49e-06 0.453 0.380 0.074 3.88e-06
Height21 LDpred1.MultiPRS LDpred1.10FCVal 0.388 0.364 0.023 2.18e-01 0.402 0.380 0.023 1.18e-02
Height21 LDpred2.PseudoVal LDpred1.10FCVal 0.432 0.364 0.068 3.24e-29 0.446 0.380 0.066 1.70e-08
Height21 SBLUP.Inf LDpred1.10FCVal 0.381 0.364 0.017 7.68e-05 0.392 0.380 0.013 1.34e-01
Height21 pT+clump.MultiPRS LDpred1.10FCVal 0.403 0.364 0.039 3.89e-02 0.396 0.380 0.017 3.84e-01
Height21 LDpred2.Inf LDpred1.10FCVal 0.388 0.364 0.024 4.73e-08 0.400 0.380 0.020 1.76e-02
Height21 lassosum.MultiPRS LDpred1.10FCVal 0.439 0.364 0.075 5.16e-05 0.445 0.380 0.066 5.42e-05
Height21 LDpred1.10FCVal LDpred1.10FCVal 0.364 0.364 0.000 1.00e+00 0.380 0.380 0.000 1.00e+00
Height21 SBayesR.PseudoVal LDpred1.10FCVal 0.434 0.364 0.070 4.03e-26 0.467 0.380 0.087 1.67e-11
Height21 LDpred2.MultiPRS LDpred2.MultiPRS 0.447 0.447 0.000 1.00e+00 0.459 0.459 0.000 1.00e+00
Height21 lassosum.10FCVal LDpred2.MultiPRS 0.436 0.447 -0.012 5.16e-01 0.442 0.459 -0.016 9.35e-02
Height21 All.MultiPRS LDpred2.MultiPRS 0.453 0.447 0.006 7.53e-01 0.453 0.459 -0.005 2.31e-01
Height21 LDpred1.MultiPRS LDpred2.MultiPRS 0.388 0.447 -0.060 9.89e-04 0.402 0.459 -0.056 1.20e-05
Height21 DBSLMM.PseudoVal LDpred2.MultiPRS 0.418 0.447 -0.029 1.05e-01 0.437 0.459 -0.022 4.70e-02
Height21 LDpred1.Inf LDpred2.MultiPRS 0.381 0.447 -0.067 2.43e-04 0.394 0.459 -0.064 3.44e-06
Height21 LDpred2.Inf LDpred2.MultiPRS 0.388 0.447 -0.059 1.11e-03 0.400 0.459 -0.059 7.28e-06
Height21 lassosum.MultiPRS LDpred2.MultiPRS 0.439 0.447 -0.008 6.55e-01 0.445 0.459 -0.014 1.37e-01
Height21 LDpred1.10FCVal LDpred2.MultiPRS 0.364 0.447 -0.083 5.74e-06 0.380 0.459 -0.079 9.10e-08
Height21 pT+clump.MultiPRS LDpred2.MultiPRS 0.403 0.447 -0.044 1.46e-02 0.396 0.459 -0.062 6.60e-06
Height21 SBayesR.PseudoVal LDpred2.MultiPRS 0.434 0.447 -0.013 4.59e-01 0.467 0.459 0.008 1.92e-01
Height21 pT+clump.10FCVal LDpred2.MultiPRS 0.388 0.447 -0.059 1.10e-03 0.353 0.459 -0.106 2.98e-09
Height21 lassosum.PseudoVal LDpred2.MultiPRS 0.355 0.447 -0.093 5.19e-07 0.351 0.459 -0.107 1.61e-07
Height21 LDpred2.10FCVal LDpred2.MultiPRS 0.447 0.447 0.000 9.96e-01 0.453 0.459 -0.006 5.27e-02
Height21 LDpred2.PseudoVal LDpred2.MultiPRS 0.432 0.447 -0.015 3.97e-01 0.446 0.459 -0.013 3.94e-02
Height21 SBLUP.Inf LDpred2.MultiPRS 0.381 0.447 -0.066 2.71e-04 0.392 0.459 -0.066 1.26e-06
Height21 LDpred2.MultiPRS LDpred2.10FCVal 0.447 0.447 0.000 9.96e-01 0.459 0.453 0.006 5.27e-02
Height21 pT+clump.10FCVal LDpred2.10FCVal 0.388 0.447 -0.059 7.02e-11 0.353 0.453 -0.100 1.99e-08
Height21 lassosum.10FCVal LDpred2.10FCVal 0.436 0.447 -0.011 1.35e-02 0.442 0.453 -0.010 2.63e-01
Height21 All.MultiPRS LDpred2.10FCVal 0.453 0.447 0.006 7.50e-01 0.453 0.453 0.001 9.12e-01
Height21 LDpred1.MultiPRS LDpred2.10FCVal 0.388 0.447 -0.060 1.14e-03 0.402 0.453 -0.050 1.33e-04
Height21 LDpred2.PseudoVal LDpred2.10FCVal 0.432 0.447 -0.015 2.82e-06 0.446 0.453 -0.007 2.71e-01
Height21 DBSLMM.PseudoVal LDpred2.10FCVal 0.418 0.447 -0.029 1.75e-07 0.437 0.453 -0.016 1.56e-01
Height21 LDpred1.Inf LDpred2.10FCVal 0.381 0.447 -0.067 1.08e-20 0.394 0.453 -0.058 4.17e-05
Height21 LDpred2.Inf LDpred2.10FCVal 0.388 0.447 -0.059 2.54e-18 0.400 0.453 -0.053 9.95e-05
Height21 lassosum.MultiPRS LDpred2.10FCVal 0.439 0.447 -0.008 6.60e-01 0.445 0.453 -0.008 3.94e-01
Height21 LDpred1.10FCVal LDpred2.10FCVal 0.364 0.447 -0.083 2.11e-26 0.380 0.453 -0.073 1.50e-06
Height21 pT+clump.MultiPRS LDpred2.10FCVal 0.403 0.447 -0.044 1.53e-02 0.396 0.453 -0.057 3.82e-05
Height21 SBayesR.PseudoVal LDpred2.10FCVal 0.434 0.447 -0.013 9.07e-05 0.467 0.453 0.014 2.82e-02
Height21 lassosum.PseudoVal LDpred2.10FCVal 0.355 0.447 -0.093 1.24e-18 0.351 0.453 -0.101 7.30e-07
Height21 LDpred2.10FCVal LDpred2.10FCVal 0.447 0.447 0.000 1.00e+00 0.453 0.453 0.000 1.00e+00
Height21 SBLUP.Inf LDpred2.10FCVal 0.381 0.447 -0.066 1.08e-20 0.392 0.453 -0.060 1.82e-05
Height21 LDpred2.MultiPRS LDpred2.PseudoVal 0.447 0.432 0.015 3.97e-01 0.459 0.446 0.013 3.94e-02
Height21 lassosum.10FCVal LDpred2.PseudoVal 0.436 0.432 0.004 5.72e-01 0.442 0.446 -0.003 7.87e-01
Height21 All.MultiPRS LDpred2.PseudoVal 0.453 0.432 0.021 2.49e-01 0.453 0.446 0.008 3.84e-01
Height21 LDpred1.MultiPRS LDpred2.PseudoVal 0.388 0.432 -0.045 1.56e-02 0.402 0.446 -0.043 9.52e-06
Height21 DBSLMM.PseudoVal LDpred2.PseudoVal 0.418 0.432 -0.014 6.57e-03 0.437 0.446 -0.009 4.07e-01
Height21 LDpred1.Inf LDpred2.PseudoVal 0.381 0.432 -0.052 2.30e-23 0.394 0.446 -0.051 7.51e-07
Height21 LDpred2.Inf LDpred2.PseudoVal 0.388 0.432 -0.044 4.41e-21 0.400 0.446 -0.046 8.90e-07
Height21 lassosum.MultiPRS LDpred2.PseudoVal 0.439 0.432 0.007 6.93e-01 0.445 0.446 -0.001 9.59e-01
Height21 LDpred1.10FCVal LDpred2.PseudoVal 0.364 0.432 -0.068 3.24e-29 0.380 0.446 -0.066 1.70e-08
Height21 pT+clump.MultiPRS LDpred2.PseudoVal 0.403 0.432 -0.029 1.11e-01 0.396 0.446 -0.050 1.33e-03
Height21 SBayesR.PseudoVal LDpred2.PseudoVal 0.434 0.432 0.002 5.62e-01 0.467 0.446 0.021 6.99e-04
Height21 pT+clump.10FCVal LDpred2.PseudoVal 0.388 0.432 -0.044 2.10e-05 0.353 0.446 -0.093 7.36e-06
Height21 lassosum.PseudoVal LDpred2.PseudoVal 0.355 0.432 -0.078 8.78e-11 0.351 0.446 -0.094 5.16e-05
Height21 LDpred2.10FCVal LDpred2.PseudoVal 0.447 0.432 0.015 2.82e-06 0.453 0.446 0.007 2.71e-01
Height21 LDpred2.PseudoVal LDpred2.PseudoVal 0.432 0.432 0.000 1.00e+00 0.446 0.446 0.000 1.00e+00
Height21 SBLUP.Inf LDpred2.PseudoVal 0.381 0.432 -0.051 6.61e-25 0.392 0.446 -0.053 5.62e-08
Height21 DBSLMM.PseudoVal LDpred2.Inf 0.418 0.388 0.030 2.22e-07 0.437 0.400 0.037 2.24e-03
Height21 LDpred2.MultiPRS LDpred2.Inf 0.447 0.388 0.059 1.11e-03 0.459 0.400 0.059 7.28e-06
Height21 pT+clump.10FCVal LDpred2.Inf 0.388 0.388 0.000 9.96e-01 0.353 0.400 -0.047 4.48e-02
Height21 lassosum.PseudoVal LDpred2.Inf 0.355 0.388 -0.033 1.23e-02 0.351 0.400 -0.049 5.98e-02
Height21 lassosum.10FCVal LDpred2.Inf 0.436 0.388 0.048 1.61e-08 0.442 0.400 0.042 1.21e-02
Height21 All.MultiPRS LDpred2.Inf 0.453 0.388 0.065 3.71e-04 0.453 0.400 0.053 2.35e-04
Height21 LDpred1.MultiPRS LDpred2.Inf 0.388 0.388 0.000 9.82e-01 0.402 0.400 0.002 7.52e-01
Height21 LDpred2.PseudoVal LDpred2.Inf 0.432 0.388 0.044 4.41e-21 0.446 0.400 0.046 8.90e-07
Height21 SBLUP.Inf LDpred2.Inf 0.381 0.388 -0.007 5.17e-04 0.392 0.400 -0.008 5.59e-02
Height21 LDpred1.Inf LDpred2.Inf 0.381 0.388 -0.008 2.82e-03 0.394 0.400 -0.006 2.74e-01
Height21 LDpred2.Inf LDpred2.Inf 0.388 0.388 0.000 1.00e+00 0.400 0.400 0.000 1.00e+00
Height21 lassosum.MultiPRS LDpred2.Inf 0.439 0.388 0.051 5.20e-03 0.445 0.400 0.045 2.37e-03
Height21 LDpred1.10FCVal LDpred2.Inf 0.364 0.388 -0.024 4.73e-08 0.380 0.400 -0.020 1.76e-02
Height21 pT+clump.MultiPRS LDpred2.Inf 0.403 0.388 0.015 4.23e-01 0.396 0.400 -0.004 8.30e-01
Height21 SBayesR.PseudoVal LDpred2.Inf 0.434 0.388 0.046 3.61e-16 0.467 0.400 0.067 2.22e-09
Height21 LDpred2.10FCVal LDpred2.Inf 0.447 0.388 0.059 2.54e-18 0.453 0.400 0.053 9.95e-05
Height21 All.MultiPRS pT+clump.MultiPRS 0.453 0.403 0.050 6.57e-03 0.453 0.396 0.057 1.00e-06
Height21 LDpred1.MultiPRS pT+clump.MultiPRS 0.388 0.403 -0.015 4.13e-01 0.402 0.396 0.006 7.18e-01
Height21 LDpred2.PseudoVal pT+clump.MultiPRS 0.432 0.403 0.029 1.11e-01 0.446 0.396 0.050 1.33e-03
Height21 DBSLMM.PseudoVal pT+clump.MultiPRS 0.418 0.403 0.015 4.03e-01 0.437 0.396 0.041 1.99e-03
Height21 LDpred1.Inf pT+clump.MultiPRS 0.381 0.403 -0.023 2.29e-01 0.394 0.396 -0.002 9.18e-01
Height21 LDpred2.Inf pT+clump.MultiPRS 0.388 0.403 -0.015 4.23e-01 0.400 0.396 0.004 8.30e-01
Height21 lassosum.MultiPRS pT+clump.MultiPRS 0.439 0.403 0.036 4.94e-02 0.445 0.396 0.049 1.27e-04
Height21 LDpred1.10FCVal pT+clump.MultiPRS 0.364 0.403 -0.039 3.89e-02 0.380 0.396 -0.017 3.84e-01
Height21 lassosum.10FCVal pT+clump.MultiPRS 0.436 0.403 0.033 7.29e-02 0.442 0.396 0.046 4.49e-04
Height21 LDpred2.MultiPRS pT+clump.MultiPRS 0.447 0.403 0.044 1.46e-02 0.459 0.396 0.062 6.60e-06
Height21 pT+clump.10FCVal pT+clump.MultiPRS 0.388 0.403 -0.015 4.26e-01 0.353 0.396 -0.043 3.12e-06
Height21 lassosum.PseudoVal pT+clump.MultiPRS 0.355 0.403 -0.048 1.08e-02 0.351 0.396 -0.045 2.81e-02
Height21 LDpred2.10FCVal pT+clump.MultiPRS 0.447 0.403 0.044 1.53e-02 0.453 0.396 0.057 3.82e-05
Height21 SBayesR.PseudoVal pT+clump.MultiPRS 0.434 0.403 0.031 8.92e-02 0.467 0.396 0.070 1.78e-07
Height21 SBLUP.Inf pT+clump.MultiPRS 0.381 0.403 -0.022 2.41e-01 0.392 0.396 -0.004 8.28e-01
Height21 pT+clump.MultiPRS pT+clump.MultiPRS 0.403 0.403 0.000 1.00e+00 0.396 0.396 0.000 1.00e+00
Height21 lassosum.10FCVal pT+clump.10FCVal 0.436 0.388 0.048 1.06e-08 0.442 0.353 0.089 3.47e-08
Height21 All.MultiPRS pT+clump.10FCVal 0.453 0.388 0.065 3.99e-04 0.453 0.353 0.100 1.16e-11
Height21 DBSLMM.PseudoVal pT+clump.10FCVal 0.418 0.388 0.030 1.21e-03 0.437 0.353 0.084 5.41e-06
Height21 LDpred1.Inf pT+clump.10FCVal 0.381 0.388 -0.008 5.09e-01 0.394 0.353 0.041 7.59e-02
Height21 LDpred2.Inf pT+clump.10FCVal 0.388 0.388 0.000 9.96e-01 0.400 0.353 0.047 4.48e-02
Height21 lassosum.MultiPRS pT+clump.10FCVal 0.439 0.388 0.051 5.34e-03 0.445 0.353 0.092 1.61e-08
Height21 LDpred1.10FCVal pT+clump.10FCVal 0.364 0.388 -0.024 4.79e-02 0.380 0.353 0.027 2.73e-01
Height21 pT+clump.MultiPRS pT+clump.10FCVal 0.403 0.388 0.015 4.26e-01 0.396 0.353 0.043 3.12e-06
Height21 LDpred2.MultiPRS pT+clump.10FCVal 0.447 0.388 0.059 1.10e-03 0.459 0.353 0.106 2.98e-09
Height21 pT+clump.10FCVal pT+clump.10FCVal 0.388 0.388 0.000 1.00e+00 0.353 0.353 0.000 1.00e+00
Height21 lassosum.PseudoVal pT+clump.10FCVal 0.355 0.388 -0.033 1.74e-03 0.351 0.353 -0.002 9.38e-01
Height21 LDpred2.10FCVal pT+clump.10FCVal 0.447 0.388 0.059 7.02e-11 0.453 0.353 0.100 1.99e-08
Height21 SBayesR.PseudoVal pT+clump.10FCVal 0.434 0.388 0.046 6.52e-07 0.467 0.353 0.114 6.16e-10
Height21 LDpred1.MultiPRS pT+clump.10FCVal 0.388 0.388 0.000 9.80e-01 0.402 0.353 0.049 2.96e-02
Height21 LDpred2.PseudoVal pT+clump.10FCVal 0.432 0.388 0.044 2.10e-05 0.446 0.353 0.093 7.36e-06
Height21 SBLUP.Inf pT+clump.10FCVal 0.381 0.388 -0.007 5.45e-01 0.392 0.353 0.039 9.29e-02
Height21 LDpred1.Inf SBayesR.PseudoVal 0.381 0.434 -0.054 2.43e-20 0.394 0.467 -0.072 3.56e-10
Height21 DBSLMM.PseudoVal SBayesR.PseudoVal 0.418 0.434 -0.016 6.40e-04 0.437 0.467 -0.030 1.23e-03
Height21 lassosum.10FCVal SBayesR.PseudoVal 0.436 0.434 0.002 7.63e-01 0.442 0.467 -0.024 2.28e-02
Height21 LDpred2.MultiPRS SBayesR.PseudoVal 0.447 0.434 0.013 4.59e-01 0.459 0.467 -0.008 1.92e-01
Height21 pT+clump.10FCVal SBayesR.PseudoVal 0.388 0.434 -0.046 6.52e-07 0.353 0.467 -0.114 6.16e-10
Height21 lassosum.PseudoVal SBayesR.PseudoVal 0.355 0.434 -0.079 8.89e-13 0.351 0.467 -0.115 6.48e-08
Height21 LDpred2.10FCVal SBayesR.PseudoVal 0.447 0.434 0.013 9.07e-05 0.453 0.467 -0.014 2.82e-02
Height21 All.MultiPRS SBayesR.PseudoVal 0.453 0.434 0.019 2.94e-01 0.453 0.467 -0.013 7.74e-02
Height21 LDpred1.MultiPRS SBayesR.PseudoVal 0.388 0.434 -0.047 1.17e-02 0.402 0.467 -0.064 3.18e-09
Height21 LDpred2.PseudoVal SBayesR.PseudoVal 0.432 0.434 -0.002 5.62e-01 0.446 0.467 -0.021 6.99e-04
Height21 SBLUP.Inf SBayesR.PseudoVal 0.381 0.434 -0.053 5.25e-20 0.392 0.467 -0.074 1.15e-10
Height21 pT+clump.MultiPRS SBayesR.PseudoVal 0.403 0.434 -0.031 8.92e-02 0.396 0.467 -0.070 1.78e-07
Height21 LDpred2.Inf SBayesR.PseudoVal 0.388 0.434 -0.046 3.61e-16 0.400 0.467 -0.067 2.22e-09
Height21 lassosum.MultiPRS SBayesR.PseudoVal 0.439 0.434 0.005 7.72e-01 0.445 0.467 -0.022 2.36e-02
Height21 LDpred1.10FCVal SBayesR.PseudoVal 0.364 0.434 -0.070 4.03e-26 0.380 0.467 -0.087 1.67e-11
Height21 SBayesR.PseudoVal SBayesR.PseudoVal 0.434 0.434 0.000 1.00e+00 0.467 0.467 0.000 1.00e+00
Height21 All.MultiPRS SBLUP.Inf 0.453 0.381 0.072 8.46e-05 0.453 0.392 0.061 4.66e-05
Height21 LDpred1.Inf SBLUP.Inf 0.381 0.381 -0.001 8.25e-01 0.394 0.392 0.002 6.94e-01
Height21 LDpred2.Inf SBLUP.Inf 0.388 0.381 0.007 5.17e-04 0.400 0.392 0.008 5.59e-02
Height21 DBSLMM.PseudoVal SBLUP.Inf 0.418 0.381 0.037 2.01e-10 0.437 0.392 0.045 2.25e-04
Height21 lassosum.10FCVal SBLUP.Inf 0.436 0.381 0.055 2.42e-10 0.442 0.392 0.050 3.74e-03
Height21 LDpred2.MultiPRS SBLUP.Inf 0.447 0.381 0.066 2.71e-04 0.459 0.392 0.066 1.26e-06
Height21 pT+clump.10FCVal SBLUP.Inf 0.388 0.381 0.007 5.45e-01 0.353 0.392 -0.039 9.29e-02
Height21 lassosum.PseudoVal SBLUP.Inf 0.355 0.381 -0.026 5.17e-02 0.351 0.392 -0.041 1.20e-01
Height21 LDpred2.10FCVal SBLUP.Inf 0.447 0.381 0.066 1.08e-20 0.453 0.392 0.060 1.82e-05
Height21 SBayesR.PseudoVal SBLUP.Inf 0.434 0.381 0.053 5.25e-20 0.467 0.392 0.074 1.15e-10
Height21 LDpred1.MultiPRS SBLUP.Inf 0.388 0.381 0.007 7.28e-01 0.402 0.392 0.010 1.81e-01
Height21 LDpred2.PseudoVal SBLUP.Inf 0.432 0.381 0.051 6.61e-25 0.446 0.392 0.053 5.62e-08
Height21 SBLUP.Inf SBLUP.Inf 0.381 0.381 0.000 1.00e+00 0.392 0.392 0.000 1.00e+00
Height21 pT+clump.MultiPRS SBLUP.Inf 0.403 0.381 0.022 2.41e-01 0.396 0.392 0.004 8.28e-01
Height21 lassosum.MultiPRS SBLUP.Inf 0.439 0.381 0.058 1.55e-03 0.445 0.392 0.053 5.17e-04
Height21 LDpred1.10FCVal SBLUP.Inf 0.364 0.381 -0.017 7.68e-05 0.380 0.392 -0.013 1.34e-01
BMI21 lassosum.10FCVal All.MultiPRS 0.359 0.378 -0.020 3.17e-01 0.333 0.346 -0.014 1.87e-01
BMI21 All.MultiPRS All.MultiPRS 0.378 0.378 0.000 1.00e+00 0.346 0.346 0.000 1.00e+00
BMI21 DBSLMM.PseudoVal All.MultiPRS 0.357 0.378 -0.021 2.76e-01 0.320 0.346 -0.026 1.84e-02
BMI21 LDpred1.Inf All.MultiPRS 0.346 0.378 -0.033 9.76e-02 0.316 0.346 -0.031 1.83e-02
BMI21 LDpred2.Inf All.MultiPRS 0.350 0.378 -0.028 1.55e-01 0.319 0.346 -0.027 2.38e-02
BMI21 lassosum.MultiPRS All.MultiPRS 0.365 0.378 -0.013 4.96e-01 0.337 0.346 -0.009 2.59e-01
BMI21 LDpred1.10FCVal All.MultiPRS 0.336 0.378 -0.043 3.11e-02 0.313 0.346 -0.033 1.86e-02
BMI21 pT+clump.MultiPRS All.MultiPRS 0.320 0.378 -0.058 3.22e-03 0.283 0.346 -0.063 6.74e-05
BMI21 LDpred2.MultiPRS All.MultiPRS 0.377 0.378 -0.001 5.77e-01 0.342 0.346 -0.004 3.42e-01
BMI21 pT+clump.10FCVal All.MultiPRS 0.312 0.378 -0.066 9.60e-04 0.285 0.346 -0.062 4.35e-04
BMI21 lassosum.PseudoVal All.MultiPRS 0.284 0.378 -0.095 1.83e-06 0.229 0.346 -0.118 1.15e-08
BMI21 LDpred2.10FCVal All.MultiPRS 0.377 0.378 -0.001 9.44e-01 0.336 0.346 -0.010 2.98e-02
BMI21 SBayesR.PseudoVal All.MultiPRS 0.373 0.378 -0.006 7.63e-01 0.338 0.346 -0.009 2.37e-01
BMI21 LDpred1.MultiPRS All.MultiPRS 0.348 0.378 -0.030 1.71e-07 0.320 0.346 -0.027 2.42e-02
BMI21 LDpred2.PseudoVal All.MultiPRS 0.378 0.378 -0.001 9.77e-01 0.348 0.346 0.002 7.10e-01
BMI21 SBLUP.Inf All.MultiPRS 0.347 0.378 -0.031 1.15e-01 0.311 0.346 -0.036 4.62e-03
BMI21 LDpred2.MultiPRS DBSLMM.PseudoVal 0.377 0.357 0.020 3.03e-01 0.342 0.320 0.022 3.38e-02
BMI21 pT+clump.10FCVal DBSLMM.PseudoVal 0.312 0.357 -0.045 3.27e-08 0.285 0.320 -0.036 2.72e-02
BMI21 lassosum.10FCVal DBSLMM.PseudoVal 0.359 0.357 0.002 7.34e-01 0.333 0.320 0.013 2.61e-01
BMI21 All.MultiPRS DBSLMM.PseudoVal 0.378 0.357 0.021 2.76e-01 0.346 0.320 0.026 1.84e-02
BMI21 LDpred1.MultiPRS DBSLMM.PseudoVal 0.348 0.357 -0.009 6.64e-01 0.320 0.320 0.000 9.82e-01
BMI21 LDpred2.PseudoVal DBSLMM.PseudoVal 0.378 0.357 0.021 4.87e-05 0.348 0.320 0.028 6.77e-03
BMI21 DBSLMM.PseudoVal DBSLMM.PseudoVal 0.357 0.357 0.000 1.00e+00 0.320 0.320 0.000 1.00e+00
BMI21 LDpred1.Inf DBSLMM.PseudoVal 0.346 0.357 -0.011 5.84e-02 0.316 0.320 -0.004 7.22e-01
BMI21 LDpred2.Inf DBSLMM.PseudoVal 0.350 0.357 -0.007 2.63e-01 0.319 0.320 -0.001 9.28e-01
BMI21 lassosum.MultiPRS DBSLMM.PseudoVal 0.365 0.357 0.008 6.74e-01 0.337 0.320 0.017 1.42e-01
BMI21 LDpred1.10FCVal DBSLMM.PseudoVal 0.336 0.357 -0.021 2.44e-03 0.313 0.320 -0.007 6.07e-01
BMI21 pT+clump.MultiPRS DBSLMM.PseudoVal 0.320 0.357 -0.037 6.66e-02 0.283 0.320 -0.037 9.66e-03
BMI21 SBayesR.PseudoVal DBSLMM.PseudoVal 0.373 0.357 0.016 3.39e-04 0.338 0.320 0.018 4.58e-02
BMI21 lassosum.PseudoVal DBSLMM.PseudoVal 0.284 0.357 -0.073 4.86e-14 0.229 0.320 -0.092 1.15e-05
BMI21 LDpred2.10FCVal DBSLMM.PseudoVal 0.377 0.357 0.020 1.44e-04 0.336 0.320 0.016 1.42e-01
BMI21 SBLUP.Inf DBSLMM.PseudoVal 0.347 0.357 -0.010 1.03e-01 0.311 0.320 -0.010 4.23e-01
BMI21 All.MultiPRS lassosum.MultiPRS 0.378 0.365 0.013 4.96e-01 0.346 0.337 0.009 2.59e-01
BMI21 LDpred1.MultiPRS lassosum.MultiPRS 0.348 0.365 -0.017 3.88e-01 0.320 0.337 -0.017 2.02e-01
BMI21 LDpred1.Inf lassosum.MultiPRS 0.346 0.365 -0.020 3.16e-01 0.316 0.337 -0.021 1.39e-01
BMI21 LDpred2.Inf lassosum.MultiPRS 0.350 0.365 -0.015 4.45e-01 0.319 0.337 -0.018 2.08e-01
BMI21 lassosum.MultiPRS lassosum.MultiPRS 0.365 0.365 0.000 1.00e+00 0.337 0.337 0.000 1.00e+00
BMI21 DBSLMM.PseudoVal lassosum.MultiPRS 0.357 0.365 -0.008 6.74e-01 0.320 0.337 -0.017 1.42e-01
BMI21 lassosum.10FCVal lassosum.MultiPRS 0.359 0.365 -0.006 7.46e-01 0.333 0.337 -0.004 5.09e-01
BMI21 LDpred2.MultiPRS lassosum.MultiPRS 0.377 0.365 0.012 5.35e-01 0.342 0.337 0.005 6.11e-01
BMI21 pT+clump.10FCVal lassosum.MultiPRS 0.312 0.365 -0.053 7.53e-03 0.285 0.337 -0.053 2.36e-03
BMI21 lassosum.PseudoVal lassosum.MultiPRS 0.284 0.365 -0.082 4.66e-05 0.229 0.337 -0.109 9.77e-08
BMI21 LDpred2.10FCVal lassosum.MultiPRS 0.377 0.365 0.012 5.43e-01 0.336 0.337 -0.001 9.17e-01
BMI21 SBayesR.PseudoVal lassosum.MultiPRS 0.373 0.365 0.007 7.08e-01 0.338 0.337 0.001 9.43e-01
BMI21 LDpred2.PseudoVal lassosum.MultiPRS 0.378 0.365 0.013 5.16e-01 0.348 0.337 0.011 2.69e-01
BMI21 SBLUP.Inf lassosum.MultiPRS 0.347 0.365 -0.018 3.57e-01 0.311 0.337 -0.027 6.04e-02
BMI21 pT+clump.MultiPRS lassosum.MultiPRS 0.320 0.365 -0.045 2.41e-02 0.283 0.337 -0.054 6.29e-04
BMI21 LDpred1.10FCVal lassosum.MultiPRS 0.336 0.365 -0.030 1.34e-01 0.313 0.337 -0.024 1.20e-01
BMI21 All.MultiPRS lassosum.10FCVal 0.378 0.359 0.020 3.17e-01 0.346 0.333 0.014 1.87e-01
BMI21 LDpred1.MultiPRS lassosum.10FCVal 0.348 0.359 -0.011 5.96e-01 0.320 0.333 -0.013 2.94e-01
BMI21 LDpred2.PseudoVal lassosum.10FCVal 0.378 0.359 0.019 3.52e-05 0.348 0.333 0.016 9.89e-02
BMI21 DBSLMM.PseudoVal lassosum.10FCVal 0.357 0.359 -0.002 7.34e-01 0.320 0.333 -0.013 2.61e-01
BMI21 LDpred1.Inf lassosum.10FCVal 0.346 0.359 -0.013 3.83e-02 0.316 0.333 -0.017 1.93e-01
BMI21 LDpred2.Inf lassosum.10FCVal 0.350 0.359 -0.009 1.76e-01 0.319 0.333 -0.014 2.89e-01
BMI21 lassosum.MultiPRS lassosum.10FCVal 0.365 0.359 0.006 7.46e-01 0.337 0.333 0.004 5.09e-01
BMI21 LDpred1.10FCVal lassosum.10FCVal 0.336 0.359 -0.023 1.25e-03 0.313 0.333 -0.020 1.70e-01
BMI21 lassosum.10FCVal lassosum.10FCVal 0.359 0.359 0.000 1.00e+00 0.333 0.333 0.000 1.00e+00
BMI21 LDpred2.MultiPRS lassosum.10FCVal 0.377 0.359 0.018 3.48e-01 0.342 0.333 0.009 3.35e-01
BMI21 pT+clump.10FCVal lassosum.10FCVal 0.312 0.359 -0.046 3.12e-09 0.285 0.333 -0.048 2.17e-03
BMI21 lassosum.PseudoVal lassosum.10FCVal 0.284 0.359 -0.075 4.60e-14 0.229 0.333 -0.104 1.12e-06
BMI21 LDpred2.10FCVal lassosum.10FCVal 0.377 0.359 0.018 1.57e-04 0.336 0.333 0.003 7.43e-01
BMI21 SBayesR.PseudoVal lassosum.10FCVal 0.373 0.359 0.014 3.06e-03 0.338 0.333 0.005 6.01e-01
BMI21 SBLUP.Inf lassosum.10FCVal 0.347 0.359 -0.012 6.55e-02 0.311 0.333 -0.022 7.99e-02
BMI21 pT+clump.MultiPRS lassosum.10FCVal 0.320 0.359 -0.039 5.38e-02 0.283 0.333 -0.050 7.63e-04
BMI21 All.MultiPRS lassosum.PseudoVal 0.378 0.284 0.095 1.83e-06 0.346 0.229 0.118 1.15e-08
BMI21 LDpred1.MultiPRS lassosum.PseudoVal 0.348 0.284 0.065 1.26e-03 0.320 0.229 0.091 2.85e-04
BMI21 LDpred1.Inf lassosum.PseudoVal 0.346 0.284 0.062 4.58e-07 0.316 0.229 0.087 7.00e-04
BMI21 LDpred2.Inf lassosum.PseudoVal 0.350 0.284 0.067 8.23e-08 0.319 0.229 0.090 5.64e-04
BMI21 lassosum.MultiPRS lassosum.PseudoVal 0.365 0.284 0.082 4.66e-05 0.337 0.229 0.109 9.77e-08
BMI21 DBSLMM.PseudoVal lassosum.PseudoVal 0.357 0.284 0.073 4.86e-14 0.320 0.229 0.092 1.15e-05
BMI21 lassosum.10FCVal lassosum.PseudoVal 0.359 0.284 0.075 4.60e-14 0.333 0.229 0.104 1.12e-06
BMI21 LDpred2.MultiPRS lassosum.PseudoVal 0.377 0.284 0.094 2.46e-06 0.342 0.229 0.114 8.46e-08
BMI21 pT+clump.10FCVal lassosum.PseudoVal 0.312 0.284 0.029 2.47e-02 0.285 0.229 0.056 3.34e-02
BMI21 lassosum.PseudoVal lassosum.PseudoVal 0.284 0.284 0.000 1.00e+00 0.229 0.229 0.000 1.00e+00
BMI21 LDpred2.10FCVal lassosum.PseudoVal 0.377 0.284 0.094 1.57e-20 0.336 0.229 0.108 2.33e-07
BMI21 SBayesR.PseudoVal lassosum.PseudoVal 0.373 0.284 0.089 3.73e-19 0.338 0.229 0.109 1.41e-07
BMI21 LDpred2.PseudoVal lassosum.PseudoVal 0.378 0.284 0.094 9.27e-18 0.348 0.229 0.120 1.60e-07
BMI21 SBLUP.Inf lassosum.PseudoVal 0.347 0.284 0.064 3.01e-07 0.311 0.229 0.082 1.51e-03
BMI21 pT+clump.MultiPRS lassosum.PseudoVal 0.320 0.284 0.037 7.23e-02 0.283 0.229 0.054 1.19e-02
BMI21 LDpred1.10FCVal lassosum.PseudoVal 0.336 0.284 0.052 4.73e-05 0.313 0.229 0.084 1.66e-03
BMI21 DBSLMM.PseudoVal LDpred1.MultiPRS 0.357 0.348 0.009 6.64e-01 0.320 0.320 0.000 9.82e-01
BMI21 LDpred2.MultiPRS LDpred1.MultiPRS 0.377 0.348 0.029 6.37e-08 0.342 0.320 0.022 3.75e-02
BMI21 pT+clump.10FCVal LDpred1.MultiPRS 0.312 0.348 -0.036 7.54e-02 0.285 0.320 -0.035 2.55e-02
BMI21 lassosum.PseudoVal LDpred1.MultiPRS 0.284 0.348 -0.065 1.26e-03 0.229 0.320 -0.091 2.85e-04
BMI21 lassosum.10FCVal LDpred1.MultiPRS 0.359 0.348 0.011 5.96e-01 0.333 0.320 0.013 2.94e-01
BMI21 All.MultiPRS LDpred1.MultiPRS 0.378 0.348 0.030 1.71e-07 0.346 0.320 0.027 2.42e-02
BMI21 LDpred1.MultiPRS LDpred1.MultiPRS 0.348 0.348 0.000 1.00e+00 0.320 0.320 0.000 1.00e+00
BMI21 LDpred2.PseudoVal LDpred1.MultiPRS 0.378 0.348 0.029 1.36e-01 0.348 0.320 0.029 2.62e-03
BMI21 SBLUP.Inf LDpred1.MultiPRS 0.347 0.348 -0.001 9.54e-01 0.311 0.320 -0.009 2.02e-01
BMI21 LDpred1.Inf LDpred1.MultiPRS 0.346 0.348 -0.003 8.90e-01 0.316 0.320 -0.004 4.89e-01
BMI21 LDpred2.Inf LDpred1.MultiPRS 0.350 0.348 0.002 9.24e-01 0.319 0.320 -0.001 9.01e-01
BMI21 lassosum.MultiPRS LDpred1.MultiPRS 0.365 0.348 0.017 3.88e-01 0.337 0.320 0.017 2.02e-01
BMI21 LDpred1.10FCVal LDpred1.MultiPRS 0.336 0.348 -0.013 5.29e-01 0.313 0.320 -0.007 3.90e-01
BMI21 pT+clump.MultiPRS LDpred1.MultiPRS 0.320 0.348 -0.028 1.60e-01 0.283 0.320 -0.037 2.24e-02
BMI21 SBayesR.PseudoVal LDpred1.MultiPRS 0.373 0.348 0.024 2.22e-01 0.338 0.320 0.018 7.63e-02
BMI21 LDpred2.10FCVal LDpred1.MultiPRS 0.377 0.348 0.029 1.47e-01 0.336 0.320 0.016 1.62e-01
BMI21 All.MultiPRS LDpred1.Inf 0.378 0.346 0.033 9.76e-02 0.346 0.316 0.031 1.83e-02
BMI21 LDpred1.Inf LDpred1.Inf 0.346 0.346 0.000 1.00e+00 0.316 0.316 0.000 1.00e+00
BMI21 LDpred2.Inf LDpred1.Inf 0.350 0.346 0.005 8.99e-02 0.319 0.316 0.003 5.77e-01
BMI21 DBSLMM.PseudoVal LDpred1.Inf 0.357 0.346 0.011 5.84e-02 0.320 0.316 0.004 7.22e-01
BMI21 lassosum.10FCVal LDpred1.Inf 0.359 0.346 0.013 3.83e-02 0.333 0.316 0.017 1.93e-01
BMI21 LDpred2.MultiPRS LDpred1.Inf 0.377 0.346 0.032 1.11e-01 0.342 0.316 0.026 2.44e-02
BMI21 pT+clump.10FCVal LDpred1.Inf 0.312 0.346 -0.033 1.48e-05 0.285 0.316 -0.031 4.54e-02
BMI21 lassosum.PseudoVal LDpred1.Inf 0.284 0.346 -0.062 4.58e-07 0.229 0.316 -0.087 7.00e-04
BMI21 LDpred2.10FCVal LDpred1.Inf 0.377 0.346 0.031 2.22e-07 0.336 0.316 0.020 1.07e-01
BMI21 SBayesR.PseudoVal LDpred1.Inf 0.373 0.346 0.027 1.97e-07 0.338 0.316 0.022 3.80e-02
BMI21 LDpred1.MultiPRS LDpred1.Inf 0.348 0.346 0.003 8.90e-01 0.320 0.316 0.004 4.89e-01
BMI21 LDpred2.PseudoVal LDpred1.Inf 0.378 0.346 0.032 1.85e-10 0.348 0.316 0.033 1.68e-03
BMI21 SBLUP.Inf LDpred1.Inf 0.347 0.346 0.002 6.10e-01 0.311 0.316 -0.005 4.37e-01
BMI21 pT+clump.MultiPRS LDpred1.Inf 0.320 0.346 -0.025 2.08e-01 0.283 0.316 -0.033 4.27e-02
BMI21 lassosum.MultiPRS LDpred1.Inf 0.365 0.346 0.020 3.16e-01 0.337 0.316 0.021 1.39e-01
BMI21 LDpred1.10FCVal LDpred1.Inf 0.336 0.346 -0.010 2.76e-02 0.313 0.316 -0.003 7.55e-01
BMI21 LDpred1.Inf LDpred1.10FCVal 0.346 0.336 0.010 2.76e-02 0.316 0.313 0.003 7.55e-01
BMI21 DBSLMM.PseudoVal LDpred1.10FCVal 0.357 0.336 0.021 2.44e-03 0.320 0.313 0.007 6.07e-01
BMI21 lassosum.10FCVal LDpred1.10FCVal 0.359 0.336 0.023 1.25e-03 0.333 0.313 0.020 1.70e-01
BMI21 LDpred2.MultiPRS LDpred1.10FCVal 0.377 0.336 0.042 3.64e-02 0.342 0.313 0.029 2.66e-02
BMI21 pT+clump.10FCVal LDpred1.10FCVal 0.312 0.336 -0.023 5.67e-03 0.285 0.313 -0.028 9.40e-02
BMI21 lassosum.PseudoVal LDpred1.10FCVal 0.284 0.336 -0.052 4.73e-05 0.229 0.313 -0.084 1.66e-03
BMI21 LDpred2.10FCVal LDpred1.10FCVal 0.377 0.336 0.041 2.70e-09 0.336 0.313 0.023 9.86e-02
BMI21 All.MultiPRS LDpred1.10FCVal 0.378 0.336 0.043 3.11e-02 0.346 0.313 0.033 1.86e-02
BMI21 LDpred1.MultiPRS LDpred1.10FCVal 0.348 0.336 0.013 5.29e-01 0.320 0.313 0.007 3.90e-01
BMI21 LDpred2.PseudoVal LDpred1.10FCVal 0.378 0.336 0.042 2.54e-12 0.348 0.313 0.035 3.12e-03
BMI21 SBLUP.Inf LDpred1.10FCVal 0.347 0.336 0.011 8.16e-03 0.311 0.313 -0.002 7.98e-01
BMI21 pT+clump.MultiPRS LDpred1.10FCVal 0.320 0.336 -0.015 4.44e-01 0.283 0.313 -0.030 9.06e-02
BMI21 LDpred2.Inf LDpred1.10FCVal 0.350 0.336 0.015 9.52e-04 0.319 0.313 0.006 5.03e-01
BMI21 lassosum.MultiPRS LDpred1.10FCVal 0.365 0.336 0.030 1.34e-01 0.337 0.313 0.024 1.20e-01
BMI21 LDpred1.10FCVal LDpred1.10FCVal 0.336 0.336 0.000 1.00e+00 0.313 0.313 0.000 1.00e+00
BMI21 SBayesR.PseudoVal LDpred1.10FCVal 0.373 0.336 0.037 3.72e-09 0.338 0.313 0.025 4.83e-02
BMI21 LDpred2.MultiPRS LDpred2.MultiPRS 0.377 0.377 0.000 1.00e+00 0.342 0.342 0.000 1.00e+00
BMI21 lassosum.10FCVal LDpred2.MultiPRS 0.359 0.377 -0.018 3.48e-01 0.333 0.342 -0.009 3.35e-01
BMI21 All.MultiPRS LDpred2.MultiPRS 0.378 0.377 0.001 5.77e-01 0.346 0.342 0.004 3.42e-01
BMI21 LDpred1.MultiPRS LDpred2.MultiPRS 0.348 0.377 -0.029 6.37e-08 0.320 0.342 -0.022 3.75e-02
BMI21 DBSLMM.PseudoVal LDpred2.MultiPRS 0.357 0.377 -0.020 3.03e-01 0.320 0.342 -0.022 3.38e-02
BMI21 LDpred1.Inf LDpred2.MultiPRS 0.346 0.377 -0.032 1.11e-01 0.316 0.342 -0.026 2.44e-02
BMI21 LDpred2.Inf LDpred2.MultiPRS 0.350 0.377 -0.027 1.73e-01 0.319 0.342 -0.023 2.83e-02
BMI21 lassosum.MultiPRS LDpred2.MultiPRS 0.365 0.377 -0.012 5.35e-01 0.337 0.342 -0.005 6.11e-01
BMI21 LDpred1.10FCVal LDpred2.MultiPRS 0.336 0.377 -0.042 3.64e-02 0.313 0.342 -0.029 2.66e-02
BMI21 pT+clump.MultiPRS LDpred2.MultiPRS 0.320 0.377 -0.057 3.87e-03 0.283 0.342 -0.059 1.06e-04
BMI21 SBayesR.PseudoVal LDpred2.MultiPRS 0.373 0.377 -0.005 8.09e-01 0.338 0.342 -0.004 4.91e-01
BMI21 pT+clump.10FCVal LDpred2.MultiPRS 0.312 0.377 -0.065 1.19e-03 0.285 0.342 -0.058 6.51e-04
BMI21 lassosum.PseudoVal LDpred2.MultiPRS 0.284 0.377 -0.094 2.46e-06 0.229 0.342 -0.114 8.46e-08
BMI21 LDpred2.10FCVal LDpred2.MultiPRS 0.377 0.377 0.000 9.93e-01 0.336 0.342 -0.006 1.84e-02
BMI21 LDpred2.PseudoVal LDpred2.MultiPRS 0.378 0.377 0.001 9.75e-01 0.348 0.342 0.006 5.86e-02
BMI21 SBLUP.Inf LDpred2.MultiPRS 0.347 0.377 -0.030 1.30e-01 0.311 0.342 -0.032 5.34e-03
BMI21 LDpred2.MultiPRS LDpred2.10FCVal 0.377 0.377 0.000 9.93e-01 0.342 0.336 0.006 1.84e-02
BMI21 pT+clump.10FCVal LDpred2.10FCVal 0.312 0.377 -0.065 9.82e-14 0.285 0.336 -0.052 2.90e-03
BMI21 lassosum.10FCVal LDpred2.10FCVal 0.359 0.377 -0.018 1.57e-04 0.333 0.336 -0.003 7.43e-01
BMI21 All.MultiPRS LDpred2.10FCVal 0.378 0.377 0.001 9.44e-01 0.346 0.336 0.010 2.98e-02
BMI21 LDpred1.MultiPRS LDpred2.10FCVal 0.348 0.377 -0.029 1.47e-01 0.320 0.336 -0.016 1.62e-01
BMI21 LDpred2.PseudoVal LDpred2.10FCVal 0.378 0.377 0.001 7.03e-01 0.348 0.336 0.012 4.57e-03
BMI21 DBSLMM.PseudoVal LDpred2.10FCVal 0.357 0.377 -0.020 1.44e-04 0.320 0.336 -0.016 1.42e-01
BMI21 LDpred1.Inf LDpred2.10FCVal 0.346 0.377 -0.031 2.22e-07 0.316 0.336 -0.020 1.07e-01
BMI21 LDpred2.Inf LDpred2.10FCVal 0.350 0.377 -0.027 1.37e-06 0.319 0.336 -0.017 1.39e-01
BMI21 lassosum.MultiPRS LDpred2.10FCVal 0.365 0.377 -0.012 5.43e-01 0.337 0.336 0.001 9.17e-01
BMI21 LDpred1.10FCVal LDpred2.10FCVal 0.336 0.377 -0.041 2.70e-09 0.313 0.336 -0.023 9.86e-02
BMI21 pT+clump.MultiPRS LDpred2.10FCVal 0.320 0.377 -0.057 4.30e-03 0.283 0.336 -0.053 5.66e-04
BMI21 SBayesR.PseudoVal LDpred2.10FCVal 0.373 0.377 -0.005 1.59e-01 0.338 0.336 0.002 7.88e-01
BMI21 lassosum.PseudoVal LDpred2.10FCVal 0.284 0.377 -0.094 1.57e-20 0.229 0.336 -0.108 2.33e-07
BMI21 LDpred2.10FCVal LDpred2.10FCVal 0.377 0.377 0.000 1.00e+00 0.336 0.336 0.000 1.00e+00
BMI21 SBLUP.Inf LDpred2.10FCVal 0.347 0.377 -0.030 9.07e-07 0.311 0.336 -0.026 3.72e-02
BMI21 LDpred2.MultiPRS LDpred2.PseudoVal 0.377 0.378 -0.001 9.75e-01 0.342 0.348 -0.006 5.86e-02
BMI21 lassosum.10FCVal LDpred2.PseudoVal 0.359 0.378 -0.019 3.52e-05 0.333 0.348 -0.016 9.89e-02
BMI21 All.MultiPRS LDpred2.PseudoVal 0.378 0.378 0.001 9.77e-01 0.346 0.348 -0.002 7.10e-01
BMI21 LDpred1.MultiPRS LDpred2.PseudoVal 0.348 0.378 -0.029 1.36e-01 0.320 0.348 -0.029 2.62e-03
BMI21 DBSLMM.PseudoVal LDpred2.PseudoVal 0.357 0.378 -0.021 4.87e-05 0.320 0.348 -0.028 6.77e-03
BMI21 LDpred1.Inf LDpred2.PseudoVal 0.346 0.378 -0.032 1.85e-10 0.316 0.348 -0.033 1.68e-03
BMI21 LDpred2.Inf LDpred2.PseudoVal 0.350 0.378 -0.028 2.23e-10 0.319 0.348 -0.029 9.00e-04
BMI21 lassosum.MultiPRS LDpred2.PseudoVal 0.365 0.378 -0.013 5.16e-01 0.337 0.348 -0.011 2.69e-01
BMI21 LDpred1.10FCVal LDpred2.PseudoVal 0.336 0.378 -0.042 2.54e-12 0.313 0.348 -0.035 3.12e-03
BMI21 pT+clump.MultiPRS LDpred2.PseudoVal 0.320 0.378 -0.058 3.77e-03 0.283 0.348 -0.065 2.59e-05
BMI21 SBayesR.PseudoVal LDpred2.PseudoVal 0.373 0.378 -0.005 9.83e-02 0.338 0.348 -0.011 1.10e-01
BMI21 pT+clump.10FCVal LDpred2.PseudoVal 0.312 0.378 -0.065 1.40e-15 0.285 0.348 -0.064 9.00e-05
BMI21 lassosum.PseudoVal LDpred2.PseudoVal 0.284 0.378 -0.094 9.27e-18 0.229 0.348 -0.120 1.60e-07
BMI21 LDpred2.10FCVal LDpred2.PseudoVal 0.377 0.378 -0.001 7.03e-01 0.336 0.348 -0.012 4.57e-03
BMI21 LDpred2.PseudoVal LDpred2.PseudoVal 0.378 0.378 0.000 1.00e+00 0.348 0.348 0.000 1.00e+00
BMI21 SBLUP.Inf LDpred2.PseudoVal 0.347 0.378 -0.031 6.87e-10 0.311 0.348 -0.038 1.29e-04
BMI21 DBSLMM.PseudoVal LDpred2.Inf 0.357 0.350 0.007 2.63e-01 0.320 0.319 0.001 9.28e-01
BMI21 LDpred2.MultiPRS LDpred2.Inf 0.377 0.350 0.027 1.73e-01 0.342 0.319 0.023 2.83e-02
BMI21 pT+clump.10FCVal LDpred2.Inf 0.312 0.350 -0.038 1.76e-06 0.285 0.319 -0.034 3.17e-02
BMI21 lassosum.PseudoVal LDpred2.Inf 0.284 0.350 -0.067 8.23e-08 0.229 0.319 -0.090 5.64e-04
BMI21 lassosum.10FCVal LDpred2.Inf 0.359 0.350 0.009 1.76e-01 0.333 0.319 0.014 2.89e-01
BMI21 All.MultiPRS LDpred2.Inf 0.378 0.350 0.028 1.55e-01 0.346 0.319 0.027 2.38e-02
BMI21 LDpred1.MultiPRS LDpred2.Inf 0.348 0.350 -0.002 9.24e-01 0.320 0.319 0.001 9.01e-01
BMI21 LDpred2.PseudoVal LDpred2.Inf 0.378 0.350 0.028 2.23e-10 0.348 0.319 0.029 9.00e-04
BMI21 SBLUP.Inf LDpred2.Inf 0.347 0.350 -0.003 2.58e-01 0.311 0.319 -0.008 1.29e-01
BMI21 LDpred1.Inf LDpred2.Inf 0.346 0.350 -0.005 8.99e-02 0.316 0.319 -0.003 5.77e-01
BMI21 LDpred2.Inf LDpred2.Inf 0.350 0.350 0.000 1.00e+00 0.319 0.319 0.000 1.00e+00
BMI21 lassosum.MultiPRS LDpred2.Inf 0.365 0.350 0.015 4.45e-01 0.337 0.319 0.018 2.08e-01
BMI21 LDpred1.10FCVal LDpred2.Inf 0.336 0.350 -0.015 9.52e-04 0.313 0.319 -0.006 5.03e-01
BMI21 pT+clump.MultiPRS LDpred2.Inf 0.320 0.350 -0.030 1.35e-01 0.283 0.319 -0.036 3.27e-02
BMI21 SBayesR.PseudoVal LDpred2.Inf 0.373 0.350 0.022 1.30e-05 0.338 0.319 0.019 7.64e-02
BMI21 LDpred2.10FCVal LDpred2.Inf 0.377 0.350 0.027 1.37e-06 0.336 0.319 0.017 1.39e-01
BMI21 All.MultiPRS pT+clump.MultiPRS 0.378 0.320 0.058 3.22e-03 0.346 0.283 0.063 6.74e-05
BMI21 LDpred1.MultiPRS pT+clump.MultiPRS 0.348 0.320 0.028 1.60e-01 0.320 0.283 0.037 2.24e-02
BMI21 LDpred2.PseudoVal pT+clump.MultiPRS 0.378 0.320 0.058 3.77e-03 0.348 0.283 0.065 2.59e-05
BMI21 DBSLMM.PseudoVal pT+clump.MultiPRS 0.357 0.320 0.037 6.66e-02 0.320 0.283 0.037 9.66e-03
BMI21 LDpred1.Inf pT+clump.MultiPRS 0.346 0.320 0.025 2.08e-01 0.316 0.283 0.033 4.27e-02
BMI21 LDpred2.Inf pT+clump.MultiPRS 0.350 0.320 0.030 1.35e-01 0.319 0.283 0.036 3.27e-02
BMI21 lassosum.MultiPRS pT+clump.MultiPRS 0.365 0.320 0.045 2.41e-02 0.337 0.283 0.054 6.29e-04
BMI21 LDpred1.10FCVal pT+clump.MultiPRS 0.336 0.320 0.015 4.44e-01 0.313 0.283 0.030 9.06e-02
BMI21 lassosum.10FCVal pT+clump.MultiPRS 0.359 0.320 0.039 5.38e-02 0.333 0.283 0.050 7.63e-04
BMI21 LDpred2.MultiPRS pT+clump.MultiPRS 0.377 0.320 0.057 3.87e-03 0.342 0.283 0.059 1.06e-04
BMI21 pT+clump.10FCVal pT+clump.MultiPRS 0.312 0.320 -0.008 7.00e-01 0.285 0.283 0.002 8.48e-01
BMI21 lassosum.PseudoVal pT+clump.MultiPRS 0.284 0.320 -0.037 7.23e-02 0.229 0.283 -0.054 1.19e-02
BMI21 LDpred2.10FCVal pT+clump.MultiPRS 0.377 0.320 0.057 4.30e-03 0.336 0.283 0.053 5.66e-04
BMI21 SBayesR.PseudoVal pT+clump.MultiPRS 0.373 0.320 0.052 8.71e-03 0.338 0.283 0.055 3.75e-05
BMI21 SBLUP.Inf pT+clump.MultiPRS 0.347 0.320 0.027 1.80e-01 0.311 0.283 0.028 9.34e-02
BMI21 pT+clump.MultiPRS pT+clump.MultiPRS 0.320 0.320 0.000 1.00e+00 0.283 0.283 0.000 1.00e+00
BMI21 lassosum.10FCVal pT+clump.10FCVal 0.359 0.312 0.046 3.12e-09 0.333 0.285 0.048 2.17e-03
BMI21 All.MultiPRS pT+clump.10FCVal 0.378 0.312 0.066 9.60e-04 0.346 0.285 0.062 4.35e-04
BMI21 DBSLMM.PseudoVal pT+clump.10FCVal 0.357 0.312 0.045 3.27e-08 0.320 0.285 0.036 2.72e-02
BMI21 LDpred1.Inf pT+clump.10FCVal 0.346 0.312 0.033 1.48e-05 0.316 0.285 0.031 4.54e-02
BMI21 LDpred2.Inf pT+clump.10FCVal 0.350 0.312 0.038 1.76e-06 0.319 0.285 0.034 3.17e-02
BMI21 lassosum.MultiPRS pT+clump.10FCVal 0.365 0.312 0.053 7.53e-03 0.337 0.285 0.053 2.36e-03
BMI21 LDpred1.10FCVal pT+clump.10FCVal 0.336 0.312 0.023 5.67e-03 0.313 0.285 0.028 9.40e-02
BMI21 pT+clump.MultiPRS pT+clump.10FCVal 0.320 0.312 0.008 7.00e-01 0.283 0.285 -0.002 8.48e-01
BMI21 LDpred2.MultiPRS pT+clump.10FCVal 0.377 0.312 0.065 1.19e-03 0.342 0.285 0.058 6.51e-04
BMI21 pT+clump.10FCVal pT+clump.10FCVal 0.312 0.312 0.000 1.00e+00 0.285 0.285 0.000 1.00e+00
BMI21 lassosum.PseudoVal pT+clump.10FCVal 0.284 0.312 -0.029 2.47e-02 0.229 0.285 -0.056 3.34e-02
BMI21 LDpred2.10FCVal pT+clump.10FCVal 0.377 0.312 0.065 9.82e-14 0.336 0.285 0.052 2.90e-03
BMI21 SBayesR.PseudoVal pT+clump.10FCVal 0.373 0.312 0.060 8.61e-16 0.338 0.285 0.053 3.99e-04
BMI21 LDpred1.MultiPRS pT+clump.10FCVal 0.348 0.312 0.036 7.54e-02 0.320 0.285 0.035 2.55e-02
BMI21 LDpred2.PseudoVal pT+clump.10FCVal 0.378 0.312 0.065 1.40e-15 0.348 0.285 0.064 9.00e-05
BMI21 SBLUP.Inf pT+clump.10FCVal 0.347 0.312 0.035 5.52e-06 0.311 0.285 0.026 9.79e-02
BMI21 LDpred1.Inf SBayesR.PseudoVal 0.346 0.373 -0.027 1.97e-07 0.316 0.338 -0.022 3.80e-02
BMI21 DBSLMM.PseudoVal SBayesR.PseudoVal 0.357 0.373 -0.016 3.39e-04 0.320 0.338 -0.018 4.58e-02
BMI21 lassosum.10FCVal SBayesR.PseudoVal 0.359 0.373 -0.014 3.06e-03 0.333 0.338 -0.005 6.01e-01
BMI21 LDpred2.MultiPRS SBayesR.PseudoVal 0.377 0.373 0.005 8.09e-01 0.342 0.338 0.004 4.91e-01
BMI21 pT+clump.10FCVal SBayesR.PseudoVal 0.312 0.373 -0.060 8.61e-16 0.285 0.338 -0.053 3.99e-04
BMI21 lassosum.PseudoVal SBayesR.PseudoVal 0.284 0.373 -0.089 3.73e-19 0.229 0.338 -0.109 1.41e-07
BMI21 LDpred2.10FCVal SBayesR.PseudoVal 0.377 0.373 0.005 1.59e-01 0.336 0.338 -0.002 7.88e-01
BMI21 All.MultiPRS SBayesR.PseudoVal 0.378 0.373 0.006 7.63e-01 0.346 0.338 0.009 2.37e-01
BMI21 LDpred1.MultiPRS SBayesR.PseudoVal 0.348 0.373 -0.024 2.22e-01 0.320 0.338 -0.018 7.63e-02
BMI21 LDpred2.PseudoVal SBayesR.PseudoVal 0.378 0.373 0.005 9.83e-02 0.348 0.338 0.011 1.10e-01
BMI21 SBLUP.Inf SBayesR.PseudoVal 0.347 0.373 -0.025 1.30e-06 0.311 0.338 -0.027 1.03e-02
BMI21 pT+clump.MultiPRS SBayesR.PseudoVal 0.320 0.373 -0.052 8.71e-03 0.283 0.338 -0.055 3.75e-05
BMI21 LDpred2.Inf SBayesR.PseudoVal 0.350 0.373 -0.022 1.30e-05 0.319 0.338 -0.019 7.64e-02
BMI21 lassosum.MultiPRS SBayesR.PseudoVal 0.365 0.373 -0.007 7.08e-01 0.337 0.338 -0.001 9.43e-01
BMI21 LDpred1.10FCVal SBayesR.PseudoVal 0.336 0.373 -0.037 3.72e-09 0.313 0.338 -0.025 4.83e-02
BMI21 SBayesR.PseudoVal SBayesR.PseudoVal 0.373 0.373 0.000 1.00e+00 0.338 0.338 0.000 1.00e+00
BMI21 All.MultiPRS SBLUP.Inf 0.378 0.347 0.031 1.15e-01 0.346 0.311 0.036 4.62e-03
BMI21 LDpred1.Inf SBLUP.Inf 0.346 0.347 -0.002 6.10e-01 0.316 0.311 0.005 4.37e-01
BMI21 LDpred2.Inf SBLUP.Inf 0.350 0.347 0.003 2.58e-01 0.319 0.311 0.008 1.29e-01
BMI21 DBSLMM.PseudoVal SBLUP.Inf 0.357 0.347 0.010 1.03e-01 0.320 0.311 0.010 4.23e-01
BMI21 lassosum.10FCVal SBLUP.Inf 0.359 0.347 0.012 6.55e-02 0.333 0.311 0.022 7.99e-02
BMI21 LDpred2.MultiPRS SBLUP.Inf 0.377 0.347 0.030 1.30e-01 0.342 0.311 0.032 5.34e-03
BMI21 pT+clump.10FCVal SBLUP.Inf 0.312 0.347 -0.035 5.52e-06 0.285 0.311 -0.026 9.79e-02
BMI21 lassosum.PseudoVal SBLUP.Inf 0.284 0.347 -0.064 3.01e-07 0.229 0.311 -0.082 1.51e-03
BMI21 LDpred2.10FCVal SBLUP.Inf 0.377 0.347 0.030 9.07e-07 0.336 0.311 0.026 3.72e-02
BMI21 SBayesR.PseudoVal SBLUP.Inf 0.373 0.347 0.025 1.30e-06 0.338 0.311 0.027 1.03e-02
BMI21 LDpred1.MultiPRS SBLUP.Inf 0.348 0.347 0.001 9.54e-01 0.320 0.311 0.009 2.02e-01
BMI21 LDpred2.PseudoVal SBLUP.Inf 0.378 0.347 0.031 6.87e-10 0.348 0.311 0.038 1.29e-04
BMI21 SBLUP.Inf SBLUP.Inf 0.347 0.347 0.000 1.00e+00 0.311 0.311 0.000 1.00e+00
BMI21 pT+clump.MultiPRS SBLUP.Inf 0.320 0.347 -0.027 1.80e-01 0.283 0.311 -0.028 9.34e-02
BMI21 lassosum.MultiPRS SBLUP.Inf 0.365 0.347 0.018 3.57e-01 0.337 0.311 0.027 6.04e-02
BMI21 LDpred1.10FCVal SBLUP.Inf 0.336 0.347 -0.011 8.16e-03 0.313 0.311 0.002 7.98e-01
GCSE lassosum.10FCVal All.MultiPRS 0.410 0.423 -0.013 4.07e-01 0.355 0.355 0.000 9.84e-01
GCSE All.MultiPRS All.MultiPRS 0.423 0.423 0.000 1.00e+00 0.355 0.355 0.000 1.00e+00
GCSE DBSLMM.PseudoVal All.MultiPRS 0.402 0.423 -0.021 1.86e-01 0.339 0.355 -0.017 2.25e-02
GCSE LDpred1.Inf All.MultiPRS 0.409 0.423 -0.014 3.75e-01 0.337 0.355 -0.019 5.70e-03
GCSE LDpred2.Inf All.MultiPRS 0.413 0.423 -0.010 5.31e-01 0.343 0.355 -0.013 2.80e-02
GCSE lassosum.MultiPRS All.MultiPRS 0.412 0.423 -0.012 4.95e-05 0.357 0.355 0.002 7.55e-01
GCSE LDpred1.10FCVal All.MultiPRS 0.405 0.423 -0.018 2.58e-01 0.337 0.355 -0.018 2.38e-02
GCSE pT+clump.MultiPRS All.MultiPRS 0.382 0.423 -0.042 9.82e-03 0.330 0.355 -0.025 1.78e-02
GCSE LDpred2.MultiPRS All.MultiPRS 0.423 0.423 0.000 8.75e-01 0.356 0.355 0.001 5.67e-01
GCSE pT+clump.10FCVal All.MultiPRS 0.374 0.423 -0.049 2.08e-03 0.315 0.355 -0.040 1.27e-03
GCSE lassosum.PseudoVal All.MultiPRS 0.316 0.423 -0.108 5.11e-11 0.273 0.355 -0.083 2.96e-06
GCSE LDpred2.10FCVal All.MultiPRS 0.423 0.423 -0.001 9.58e-01 0.358 0.355 0.003 3.42e-01
GCSE SBayesR.PseudoVal All.MultiPRS 0.420 0.423 -0.004 8.24e-01 0.350 0.355 -0.005 2.23e-01
GCSE LDpred1.MultiPRS All.MultiPRS 0.414 0.423 -0.010 5.39e-01 0.341 0.355 -0.014 1.39e-02
GCSE LDpred2.PseudoVal All.MultiPRS 0.422 0.423 -0.001 9.34e-01 0.358 0.355 0.003 3.53e-01
GCSE SBLUP.Inf All.MultiPRS 0.412 0.423 -0.012 4.63e-01 0.344 0.355 -0.011 7.74e-02
GCSE LDpred2.MultiPRS DBSLMM.PseudoVal 0.423 0.402 0.021 1.84e-01 0.356 0.339 0.018 1.77e-02
GCSE pT+clump.10FCVal DBSLMM.PseudoVal 0.374 0.402 -0.028 2.01e-05 0.315 0.339 -0.024 8.81e-02
GCSE lassosum.10FCVal DBSLMM.PseudoVal 0.410 0.402 0.008 7.96e-02 0.355 0.339 0.016 8.16e-02
GCSE All.MultiPRS DBSLMM.PseudoVal 0.423 0.402 0.021 1.86e-01 0.355 0.339 0.017 2.25e-02
GCSE LDpred1.MultiPRS DBSLMM.PseudoVal 0.414 0.402 0.011 4.92e-01 0.341 0.339 0.002 7.91e-01
GCSE LDpred2.PseudoVal DBSLMM.PseudoVal 0.422 0.402 0.020 3.13e-07 0.358 0.339 0.019 1.67e-02
GCSE DBSLMM.PseudoVal DBSLMM.PseudoVal 0.402 0.402 0.000 1.00e+00 0.339 0.339 0.000 1.00e+00
GCSE LDpred1.Inf DBSLMM.PseudoVal 0.409 0.402 0.007 1.11e-01 0.337 0.339 -0.002 8.19e-01
GCSE LDpred2.Inf DBSLMM.PseudoVal 0.413 0.402 0.011 9.10e-03 0.343 0.339 0.004 6.60e-01
GCSE lassosum.MultiPRS DBSLMM.PseudoVal 0.412 0.402 0.009 5.61e-01 0.357 0.339 0.018 3.52e-02
GCSE LDpred1.10FCVal DBSLMM.PseudoVal 0.405 0.402 0.003 5.35e-01 0.337 0.339 -0.002 8.64e-01
GCSE pT+clump.MultiPRS DBSLMM.PseudoVal 0.382 0.402 -0.021 2.04e-01 0.330 0.339 -0.009 4.34e-01
GCSE SBayesR.PseudoVal DBSLMM.PseudoVal 0.420 0.402 0.017 1.24e-06 0.350 0.339 0.011 1.37e-01
GCSE lassosum.PseudoVal DBSLMM.PseudoVal 0.316 0.402 -0.087 2.65e-25 0.273 0.339 -0.066 1.64e-04
GCSE LDpred2.10FCVal DBSLMM.PseudoVal 0.423 0.402 0.020 2.79e-07 0.358 0.339 0.020 1.83e-02
GCSE SBLUP.Inf DBSLMM.PseudoVal 0.412 0.402 0.009 2.45e-02 0.344 0.339 0.006 5.25e-01
GCSE All.MultiPRS lassosum.MultiPRS 0.423 0.412 0.012 4.95e-05 0.355 0.357 -0.002 7.55e-01
GCSE LDpred1.MultiPRS lassosum.MultiPRS 0.414 0.412 0.002 9.04e-01 0.341 0.357 -0.016 5.37e-02
GCSE LDpred1.Inf lassosum.MultiPRS 0.409 0.412 -0.002 8.81e-01 0.337 0.357 -0.021 1.33e-02
GCSE LDpred2.Inf lassosum.MultiPRS 0.413 0.412 0.002 9.11e-01 0.343 0.357 -0.014 7.59e-02
GCSE lassosum.MultiPRS lassosum.MultiPRS 0.412 0.412 0.000 1.00e+00 0.357 0.357 0.000 1.00e+00
GCSE DBSLMM.PseudoVal lassosum.MultiPRS 0.402 0.412 -0.009 5.61e-01 0.339 0.357 -0.018 3.52e-02
GCSE lassosum.10FCVal lassosum.MultiPRS 0.410 0.412 -0.001 9.27e-01 0.355 0.357 -0.002 3.85e-01
GCSE LDpred2.MultiPRS lassosum.MultiPRS 0.423 0.412 0.012 4.53e-05 0.356 0.357 -0.001 8.81e-01
GCSE pT+clump.10FCVal lassosum.MultiPRS 0.374 0.412 -0.038 1.93e-02 0.315 0.357 -0.042 1.21e-03
GCSE lassosum.PseudoVal lassosum.MultiPRS 0.316 0.412 -0.096 5.77e-09 0.273 0.357 -0.085 9.13e-07
GCSE LDpred2.10FCVal lassosum.MultiPRS 0.423 0.412 0.011 4.92e-01 0.358 0.357 0.001 8.41e-01
GCSE SBayesR.PseudoVal lassosum.MultiPRS 0.420 0.412 0.008 6.05e-01 0.350 0.357 -0.007 2.72e-01
GCSE LDpred2.PseudoVal lassosum.MultiPRS 0.422 0.412 0.010 5.12e-01 0.358 0.357 0.001 8.92e-01
GCSE SBLUP.Inf lassosum.MultiPRS 0.412 0.412 0.000 9.97e-01 0.344 0.357 -0.013 1.08e-01
GCSE pT+clump.MultiPRS lassosum.MultiPRS 0.382 0.412 -0.030 6.39e-02 0.330 0.357 -0.027 1.72e-02
GCSE LDpred1.10FCVal lassosum.MultiPRS 0.405 0.412 -0.006 6.95e-01 0.337 0.357 -0.020 3.66e-02
GCSE All.MultiPRS lassosum.10FCVal 0.423 0.410 0.013 4.07e-01 0.355 0.355 0.000 9.84e-01
GCSE LDpred1.MultiPRS lassosum.10FCVal 0.414 0.410 0.003 8.35e-01 0.341 0.355 -0.014 1.17e-01
GCSE LDpred2.PseudoVal lassosum.10FCVal 0.422 0.410 0.012 2.61e-04 0.358 0.355 0.003 6.71e-01
GCSE DBSLMM.PseudoVal lassosum.10FCVal 0.402 0.410 -0.008 7.96e-02 0.339 0.355 -0.016 8.16e-02
GCSE LDpred1.Inf lassosum.10FCVal 0.409 0.410 -0.001 8.28e-01 0.337 0.355 -0.019 3.95e-02
GCSE LDpred2.Inf lassosum.10FCVal 0.413 0.410 0.003 4.34e-01 0.343 0.355 -0.012 1.54e-01
GCSE lassosum.MultiPRS lassosum.10FCVal 0.412 0.410 0.001 9.27e-01 0.357 0.355 0.002 3.85e-01
GCSE LDpred1.10FCVal lassosum.10FCVal 0.405 0.410 -0.005 3.08e-01 0.337 0.355 -0.018 7.39e-02
GCSE lassosum.10FCVal lassosum.10FCVal 0.410 0.410 0.000 1.00e+00 0.355 0.355 0.000 1.00e+00
GCSE LDpred2.MultiPRS lassosum.10FCVal 0.423 0.410 0.013 4.02e-01 0.356 0.355 0.001 8.68e-01
GCSE pT+clump.10FCVal lassosum.10FCVal 0.374 0.410 -0.036 1.98e-09 0.315 0.355 -0.040 1.58e-03
GCSE lassosum.PseudoVal lassosum.10FCVal 0.316 0.410 -0.094 7.29e-28 0.273 0.355 -0.082 7.10e-06
GCSE LDpred2.10FCVal lassosum.10FCVal 0.423 0.410 0.012 6.62e-05 0.358 0.355 0.003 6.23e-01
GCSE SBayesR.PseudoVal lassosum.10FCVal 0.420 0.410 0.010 5.89e-03 0.350 0.355 -0.005 4.88e-01
GCSE SBLUP.Inf lassosum.10FCVal 0.412 0.410 0.002 7.09e-01 0.344 0.355 -0.011 2.09e-01
GCSE pT+clump.MultiPRS lassosum.10FCVal 0.382 0.410 -0.029 8.07e-02 0.330 0.355 -0.025 2.75e-02
GCSE All.MultiPRS lassosum.PseudoVal 0.423 0.316 0.108 5.11e-11 0.355 0.273 0.083 2.96e-06
GCSE LDpred1.MultiPRS lassosum.PseudoVal 0.414 0.316 0.098 5.43e-09 0.341 0.273 0.069 5.88e-04
GCSE LDpred1.Inf lassosum.PseudoVal 0.409 0.316 0.093 8.82e-23 0.337 0.273 0.064 1.37e-03
GCSE LDpred2.Inf lassosum.PseudoVal 0.413 0.316 0.098 8.07e-24 0.343 0.273 0.070 5.69e-04
GCSE lassosum.MultiPRS lassosum.PseudoVal 0.412 0.316 0.096 5.77e-09 0.357 0.273 0.085 9.13e-07
GCSE DBSLMM.PseudoVal lassosum.PseudoVal 0.402 0.316 0.087 2.65e-25 0.339 0.273 0.066 1.64e-04
GCSE lassosum.10FCVal lassosum.PseudoVal 0.410 0.316 0.094 7.29e-28 0.355 0.273 0.082 7.10e-06
GCSE LDpred2.MultiPRS lassosum.PseudoVal 0.423 0.316 0.108 4.73e-11 0.356 0.273 0.084 1.96e-06
GCSE pT+clump.10FCVal lassosum.PseudoVal 0.374 0.316 0.058 6.52e-08 0.315 0.273 0.043 6.49e-02
GCSE lassosum.PseudoVal lassosum.PseudoVal 0.316 0.316 0.000 1.00e+00 0.273 0.273 0.000 1.00e+00
GCSE LDpred2.10FCVal lassosum.PseudoVal 0.423 0.316 0.107 8.33e-36 0.358 0.273 0.086 1.60e-06
GCSE SBayesR.PseudoVal lassosum.PseudoVal 0.420 0.316 0.104 3.50e-36 0.350 0.273 0.077 1.01e-05
GCSE LDpred2.PseudoVal lassosum.PseudoVal 0.422 0.316 0.106 5.29e-33 0.358 0.273 0.085 3.87e-06
GCSE SBLUP.Inf lassosum.PseudoVal 0.412 0.316 0.096 1.06e-23 0.344 0.273 0.072 3.51e-04
GCSE pT+clump.MultiPRS lassosum.PseudoVal 0.382 0.316 0.066 9.99e-05 0.330 0.273 0.057 2.92e-03
GCSE LDpred1.10FCVal lassosum.PseudoVal 0.405 0.316 0.090 9.91e-20 0.337 0.273 0.064 1.90e-03
GCSE DBSLMM.PseudoVal LDpred1.MultiPRS 0.402 0.414 -0.011 4.92e-01 0.339 0.341 -0.002 7.91e-01
GCSE LDpred2.MultiPRS LDpred1.MultiPRS 0.423 0.414 0.010 5.33e-01 0.356 0.341 0.015 2.09e-02
GCSE pT+clump.10FCVal LDpred1.MultiPRS 0.374 0.414 -0.040 1.59e-02 0.315 0.341 -0.026 4.58e-02
GCSE lassosum.PseudoVal LDpred1.MultiPRS 0.316 0.414 -0.098 5.43e-09 0.273 0.341 -0.069 5.88e-04
GCSE lassosum.10FCVal LDpred1.MultiPRS 0.410 0.414 -0.003 8.35e-01 0.355 0.341 0.014 1.17e-01
GCSE All.MultiPRS LDpred1.MultiPRS 0.423 0.414 0.010 5.39e-01 0.355 0.341 0.014 1.39e-02
GCSE LDpred1.MultiPRS LDpred1.MultiPRS 0.414 0.414 0.000 1.00e+00 0.341 0.341 0.000 1.00e+00
GCSE LDpred2.PseudoVal LDpred1.MultiPRS 0.422 0.414 0.008 6.00e-01 0.358 0.341 0.017 1.19e-02
GCSE SBLUP.Inf LDpred1.MultiPRS 0.412 0.414 -0.002 9.08e-01 0.344 0.341 0.003 5.03e-01
GCSE LDpred1.Inf LDpred1.MultiPRS 0.409 0.414 -0.004 7.90e-01 0.337 0.341 -0.005 3.13e-01
GCSE LDpred2.Inf LDpred1.MultiPRS 0.413 0.414 0.000 9.92e-01 0.343 0.341 0.002 7.49e-01
GCSE lassosum.MultiPRS LDpred1.MultiPRS 0.412 0.414 -0.002 9.04e-01 0.357 0.341 0.016 5.37e-02
GCSE LDpred1.10FCVal LDpred1.MultiPRS 0.405 0.414 -0.008 6.15e-01 0.337 0.341 -0.004 4.62e-01
GCSE pT+clump.MultiPRS LDpred1.MultiPRS 0.382 0.414 -0.032 4.81e-02 0.330 0.341 -0.011 3.57e-01
GCSE SBayesR.PseudoVal LDpred1.MultiPRS 0.420 0.414 0.006 6.98e-01 0.350 0.341 0.009 2.36e-01
GCSE LDpred2.10FCVal LDpred1.MultiPRS 0.423 0.414 0.009 5.80e-01 0.358 0.341 0.017 1.27e-02
GCSE All.MultiPRS LDpred1.Inf 0.423 0.409 0.014 3.75e-01 0.355 0.337 0.019 5.70e-03
GCSE LDpred1.Inf LDpred1.Inf 0.409 0.409 0.000 1.00e+00 0.337 0.337 0.000 1.00e+00
GCSE LDpred2.Inf LDpred1.Inf 0.413 0.409 0.004 3.42e-02 0.343 0.337 0.006 1.39e-01
GCSE DBSLMM.PseudoVal LDpred1.Inf 0.402 0.409 -0.007 1.11e-01 0.339 0.337 0.002 8.19e-01
GCSE lassosum.10FCVal LDpred1.Inf 0.410 0.409 0.001 8.28e-01 0.355 0.337 0.019 3.95e-02
GCSE LDpred2.MultiPRS LDpred1.Inf 0.423 0.409 0.014 3.70e-01 0.356 0.337 0.020 4.06e-03
GCSE pT+clump.10FCVal LDpred1.Inf 0.374 0.409 -0.035 5.56e-09 0.315 0.337 -0.021 9.35e-02
GCSE lassosum.PseudoVal LDpred1.Inf 0.316 0.409 -0.093 8.82e-23 0.273 0.337 -0.064 1.37e-03
GCSE LDpred2.10FCVal LDpred1.Inf 0.423 0.409 0.013 8.40e-05 0.358 0.337 0.022 2.52e-03
GCSE SBayesR.PseudoVal LDpred1.Inf 0.420 0.409 0.011 4.02e-03 0.350 0.337 0.013 8.36e-02
GCSE LDpred1.MultiPRS LDpred1.Inf 0.414 0.409 0.004 7.90e-01 0.341 0.337 0.005 3.13e-01
GCSE LDpred2.PseudoVal LDpred1.Inf 0.422 0.409 0.013 1.40e-04 0.358 0.337 0.021 2.60e-03
GCSE SBLUP.Inf LDpred1.Inf 0.412 0.409 0.002 1.91e-01 0.344 0.337 0.008 5.09e-02
GCSE pT+clump.MultiPRS LDpred1.Inf 0.382 0.409 -0.028 9.07e-02 0.330 0.337 -0.007 5.79e-01
GCSE lassosum.MultiPRS LDpred1.Inf 0.412 0.409 0.002 8.81e-01 0.357 0.337 0.021 1.33e-02
GCSE LDpred1.10FCVal LDpred1.Inf 0.405 0.409 -0.004 2.03e-01 0.337 0.337 0.000 9.59e-01
GCSE LDpred1.Inf LDpred1.10FCVal 0.409 0.405 0.004 2.03e-01 0.337 0.337 0.000 9.59e-01
GCSE DBSLMM.PseudoVal LDpred1.10FCVal 0.402 0.405 -0.003 5.35e-01 0.339 0.337 0.002 8.64e-01
GCSE lassosum.10FCVal LDpred1.10FCVal 0.410 0.405 0.005 3.08e-01 0.355 0.337 0.018 7.39e-02
GCSE LDpred2.MultiPRS LDpred1.10FCVal 0.423 0.405 0.018 2.55e-01 0.356 0.337 0.019 1.71e-02
GCSE pT+clump.10FCVal LDpred1.10FCVal 0.374 0.405 -0.031 1.51e-06 0.315 0.337 -0.022 1.15e-01
GCSE lassosum.PseudoVal LDpred1.10FCVal 0.316 0.405 -0.090 9.91e-20 0.273 0.337 -0.064 1.90e-03
GCSE LDpred2.10FCVal LDpred1.10FCVal 0.423 0.405 0.017 1.64e-05 0.358 0.337 0.021 1.28e-02
GCSE All.MultiPRS LDpred1.10FCVal 0.423 0.405 0.018 2.58e-01 0.355 0.337 0.018 2.38e-02
GCSE LDpred1.MultiPRS LDpred1.10FCVal 0.414 0.405 0.008 6.15e-01 0.341 0.337 0.004 4.62e-01
GCSE LDpred2.PseudoVal LDpred1.10FCVal 0.422 0.405 0.017 2.07e-05 0.358 0.337 0.021 1.21e-02
GCSE SBLUP.Inf LDpred1.10FCVal 0.412 0.405 0.006 1.92e-02 0.344 0.337 0.007 2.02e-01
GCSE pT+clump.MultiPRS LDpred1.10FCVal 0.382 0.405 -0.024 1.45e-01 0.330 0.337 -0.007 5.96e-01
GCSE LDpred2.Inf LDpred1.10FCVal 0.413 0.405 0.008 4.69e-03 0.343 0.337 0.006 3.35e-01
GCSE lassosum.MultiPRS LDpred1.10FCVal 0.412 0.405 0.006 6.95e-01 0.357 0.337 0.020 3.66e-02
GCSE LDpred1.10FCVal LDpred1.10FCVal 0.405 0.405 0.000 1.00e+00 0.337 0.337 0.000 1.00e+00
GCSE SBayesR.PseudoVal LDpred1.10FCVal 0.420 0.405 0.014 7.00e-04 0.350 0.337 0.013 1.53e-01
GCSE LDpred2.MultiPRS LDpred2.MultiPRS 0.423 0.423 0.000 1.00e+00 0.356 0.356 0.000 1.00e+00
GCSE lassosum.10FCVal LDpred2.MultiPRS 0.410 0.423 -0.013 4.02e-01 0.355 0.356 -0.001 8.68e-01
GCSE All.MultiPRS LDpred2.MultiPRS 0.423 0.423 0.000 8.75e-01 0.355 0.356 -0.001 5.67e-01
GCSE LDpred1.MultiPRS LDpred2.MultiPRS 0.414 0.423 -0.010 5.33e-01 0.341 0.356 -0.015 2.09e-02
GCSE DBSLMM.PseudoVal LDpred2.MultiPRS 0.402 0.423 -0.021 1.84e-01 0.339 0.356 -0.018 1.77e-02
GCSE LDpred1.Inf LDpred2.MultiPRS 0.409 0.423 -0.014 3.70e-01 0.337 0.356 -0.020 4.06e-03
GCSE LDpred2.Inf LDpred2.MultiPRS 0.413 0.423 -0.010 5.26e-01 0.343 0.356 -0.014 1.58e-02
GCSE lassosum.MultiPRS LDpred2.MultiPRS 0.412 0.423 -0.012 4.53e-05 0.357 0.356 0.001 8.81e-01
GCSE LDpred1.10FCVal LDpred2.MultiPRS 0.405 0.423 -0.018 2.55e-01 0.337 0.356 -0.019 1.71e-02
GCSE pT+clump.MultiPRS LDpred2.MultiPRS 0.382 0.423 -0.042 9.62e-03 0.330 0.356 -0.026 1.86e-02
GCSE SBayesR.PseudoVal LDpred2.MultiPRS 0.420 0.423 -0.004 8.17e-01 0.350 0.356 -0.006 1.85e-01
GCSE pT+clump.10FCVal LDpred2.MultiPRS 0.374 0.423 -0.050 2.02e-03 0.315 0.356 -0.041 1.51e-03
GCSE lassosum.PseudoVal LDpred2.MultiPRS 0.316 0.423 -0.108 4.73e-11 0.273 0.356 -0.084 1.96e-06
GCSE LDpred2.10FCVal LDpred2.MultiPRS 0.423 0.423 -0.001 9.51e-01 0.358 0.356 0.002 4.70e-01
GCSE LDpred2.PseudoVal LDpred2.MultiPRS 0.422 0.423 -0.001 9.27e-01 0.358 0.356 0.002 4.97e-01
GCSE SBLUP.Inf LDpred2.MultiPRS 0.412 0.423 -0.012 4.58e-01 0.344 0.356 -0.012 5.65e-02
GCSE LDpred2.MultiPRS LDpred2.10FCVal 0.423 0.423 0.001 9.51e-01 0.356 0.358 -0.002 4.70e-01
GCSE pT+clump.10FCVal LDpred2.10FCVal 0.374 0.423 -0.049 3.83e-15 0.315 0.358 -0.043 8.13e-04
GCSE lassosum.10FCVal LDpred2.10FCVal 0.410 0.423 -0.012 6.62e-05 0.355 0.358 -0.003 6.23e-01
GCSE All.MultiPRS LDpred2.10FCVal 0.423 0.423 0.001 9.58e-01 0.355 0.358 -0.003 3.42e-01
GCSE LDpred1.MultiPRS LDpred2.10FCVal 0.414 0.423 -0.009 5.80e-01 0.341 0.358 -0.017 1.27e-02
GCSE LDpred2.PseudoVal LDpred2.10FCVal 0.422 0.423 0.000 6.87e-01 0.358 0.358 0.000 9.06e-01
GCSE DBSLMM.PseudoVal LDpred2.10FCVal 0.402 0.423 -0.020 2.79e-07 0.339 0.358 -0.020 1.83e-02
GCSE LDpred1.Inf LDpred2.10FCVal 0.409 0.423 -0.013 8.40e-05 0.337 0.358 -0.022 2.52e-03
GCSE LDpred2.Inf LDpred2.10FCVal 0.413 0.423 -0.009 2.10e-03 0.343 0.358 -0.016 1.29e-02
GCSE lassosum.MultiPRS LDpred2.10FCVal 0.412 0.423 -0.011 4.92e-01 0.357 0.358 -0.001 8.41e-01
GCSE LDpred1.10FCVal LDpred2.10FCVal 0.405 0.423 -0.017 1.64e-05 0.337 0.358 -0.021 1.28e-02
GCSE pT+clump.MultiPRS LDpred2.10FCVal 0.382 0.423 -0.041 1.22e-02 0.330 0.358 -0.028 1.23e-02
GCSE SBayesR.PseudoVal LDpred2.10FCVal 0.420 0.423 -0.003 2.39e-01 0.350 0.358 -0.008 8.44e-02
GCSE lassosum.PseudoVal LDpred2.10FCVal 0.316 0.423 -0.107 8.33e-36 0.273 0.358 -0.086 1.60e-06
GCSE LDpred2.10FCVal LDpred2.10FCVal 0.423 0.423 0.000 1.00e+00 0.358 0.358 0.000 1.00e+00
GCSE SBLUP.Inf LDpred2.10FCVal 0.412 0.423 -0.011 6.98e-04 0.344 0.358 -0.014 3.85e-02
GCSE LDpred2.MultiPRS LDpred2.PseudoVal 0.423 0.422 0.001 9.27e-01 0.356 0.358 -0.002 4.97e-01
GCSE lassosum.10FCVal LDpred2.PseudoVal 0.410 0.422 -0.012 2.61e-04 0.355 0.358 -0.003 6.71e-01
GCSE All.MultiPRS LDpred2.PseudoVal 0.423 0.422 0.001 9.34e-01 0.355 0.358 -0.003 3.53e-01
GCSE LDpred1.MultiPRS LDpred2.PseudoVal 0.414 0.422 -0.008 6.00e-01 0.341 0.358 -0.017 1.19e-02
GCSE DBSLMM.PseudoVal LDpred2.PseudoVal 0.402 0.422 -0.020 3.13e-07 0.339 0.358 -0.019 1.67e-02
GCSE LDpred1.Inf LDpred2.PseudoVal 0.409 0.422 -0.013 1.40e-04 0.337 0.358 -0.021 2.60e-03
GCSE LDpred2.Inf LDpred2.PseudoVal 0.413 0.422 -0.009 2.22e-03 0.343 0.358 -0.015 1.02e-02
GCSE lassosum.MultiPRS LDpred2.PseudoVal 0.412 0.422 -0.010 5.12e-01 0.357 0.358 -0.001 8.92e-01
GCSE LDpred1.10FCVal LDpred2.PseudoVal 0.405 0.422 -0.017 2.07e-05 0.337 0.358 -0.021 1.21e-02
GCSE pT+clump.MultiPRS LDpred2.PseudoVal 0.382 0.422 -0.041 1.31e-02 0.330 0.358 -0.028 1.47e-02
GCSE SBayesR.PseudoVal LDpred2.PseudoVal 0.420 0.422 -0.002 3.15e-01 0.350 0.358 -0.008 7.45e-02
GCSE pT+clump.10FCVal LDpred2.PseudoVal 0.374 0.422 -0.048 1.31e-14 0.315 0.358 -0.043 9.82e-04
GCSE lassosum.PseudoVal LDpred2.PseudoVal 0.316 0.422 -0.106 5.29e-33 0.273 0.358 -0.085 3.87e-06
GCSE LDpred2.10FCVal LDpred2.PseudoVal 0.423 0.422 0.000 6.87e-01 0.358 0.358 0.000 9.06e-01
GCSE LDpred2.PseudoVal LDpred2.PseudoVal 0.422 0.422 0.000 1.00e+00 0.358 0.358 0.000 1.00e+00
GCSE SBLUP.Inf LDpred2.PseudoVal 0.412 0.422 -0.010 9.20e-04 0.344 0.358 -0.014 3.67e-02
GCSE DBSLMM.PseudoVal LDpred2.Inf 0.402 0.413 -0.011 9.10e-03 0.339 0.343 -0.004 6.60e-01
GCSE LDpred2.MultiPRS LDpred2.Inf 0.423 0.413 0.010 5.26e-01 0.356 0.343 0.014 1.58e-02
GCSE pT+clump.10FCVal LDpred2.Inf 0.374 0.413 -0.039 1.47e-10 0.315 0.343 -0.028 3.09e-02
GCSE lassosum.PseudoVal LDpred2.Inf 0.316 0.413 -0.098 8.07e-24 0.273 0.343 -0.070 5.69e-04
GCSE lassosum.10FCVal LDpred2.Inf 0.410 0.413 -0.003 4.34e-01 0.355 0.343 0.012 1.54e-01
GCSE All.MultiPRS LDpred2.Inf 0.423 0.413 0.010 5.31e-01 0.355 0.343 0.013 2.80e-02
GCSE LDpred1.MultiPRS LDpred2.Inf 0.414 0.413 0.000 9.92e-01 0.341 0.343 -0.002 7.49e-01
GCSE LDpred2.PseudoVal LDpred2.Inf 0.422 0.413 0.009 2.22e-03 0.358 0.343 0.015 1.02e-02
GCSE SBLUP.Inf LDpred2.Inf 0.412 0.413 -0.002 2.15e-01 0.344 0.343 0.002 5.61e-01
GCSE LDpred1.Inf LDpred2.Inf 0.409 0.413 -0.004 3.42e-02 0.337 0.343 -0.006 1.39e-01
GCSE LDpred2.Inf LDpred2.Inf 0.413 0.413 0.000 1.00e+00 0.343 0.343 0.000 1.00e+00
GCSE lassosum.MultiPRS LDpred2.Inf 0.412 0.413 -0.002 9.11e-01 0.357 0.343 0.014 7.59e-02
GCSE LDpred1.10FCVal LDpred2.Inf 0.405 0.413 -0.008 4.69e-03 0.337 0.343 -0.006 3.35e-01
GCSE pT+clump.MultiPRS LDpred2.Inf 0.382 0.413 -0.032 5.13e-02 0.330 0.343 -0.013 2.93e-01
GCSE SBayesR.PseudoVal LDpred2.Inf 0.420 0.413 0.006 7.92e-02 0.350 0.343 0.007 3.43e-01
GCSE LDpred2.10FCVal LDpred2.Inf 0.423 0.413 0.009 2.10e-03 0.358 0.343 0.016 1.29e-02
GCSE All.MultiPRS pT+clump.MultiPRS 0.423 0.382 0.042 9.82e-03 0.355 0.330 0.025 1.78e-02
GCSE LDpred1.MultiPRS pT+clump.MultiPRS 0.414 0.382 0.032 4.81e-02 0.341 0.330 0.011 3.57e-01
GCSE LDpred2.PseudoVal pT+clump.MultiPRS 0.422 0.382 0.041 1.31e-02 0.358 0.330 0.028 1.47e-02
GCSE DBSLMM.PseudoVal pT+clump.MultiPRS 0.402 0.382 0.021 2.04e-01 0.339 0.330 0.009 4.34e-01
GCSE LDpred1.Inf pT+clump.MultiPRS 0.409 0.382 0.028 9.07e-02 0.337 0.330 0.007 5.79e-01
GCSE LDpred2.Inf pT+clump.MultiPRS 0.413 0.382 0.032 5.13e-02 0.343 0.330 0.013 2.93e-01
GCSE lassosum.MultiPRS pT+clump.MultiPRS 0.412 0.382 0.030 6.39e-02 0.357 0.330 0.027 1.72e-02
GCSE LDpred1.10FCVal pT+clump.MultiPRS 0.405 0.382 0.024 1.45e-01 0.337 0.330 0.007 5.96e-01
GCSE lassosum.10FCVal pT+clump.MultiPRS 0.410 0.382 0.029 8.07e-02 0.355 0.330 0.025 2.75e-02
GCSE LDpred2.MultiPRS pT+clump.MultiPRS 0.423 0.382 0.042 9.62e-03 0.356 0.330 0.026 1.86e-02
GCSE pT+clump.10FCVal pT+clump.MultiPRS 0.374 0.382 -0.008 6.48e-01 0.315 0.330 -0.015 1.26e-02
GCSE lassosum.PseudoVal pT+clump.MultiPRS 0.316 0.382 -0.066 9.99e-05 0.273 0.330 -0.057 2.92e-03
GCSE LDpred2.10FCVal pT+clump.MultiPRS 0.423 0.382 0.041 1.22e-02 0.358 0.330 0.028 1.23e-02
GCSE SBayesR.PseudoVal pT+clump.MultiPRS 0.420 0.382 0.038 1.92e-02 0.350 0.330 0.020 7.53e-02
GCSE SBLUP.Inf pT+clump.MultiPRS 0.412 0.382 0.030 6.54e-02 0.344 0.330 0.014 2.19e-01
GCSE pT+clump.MultiPRS pT+clump.MultiPRS 0.382 0.382 0.000 1.00e+00 0.330 0.330 0.000 1.00e+00
GCSE lassosum.10FCVal pT+clump.10FCVal 0.410 0.374 0.036 1.98e-09 0.355 0.315 0.040 1.58e-03
GCSE All.MultiPRS pT+clump.10FCVal 0.423 0.374 0.049 2.08e-03 0.355 0.315 0.040 1.27e-03
GCSE DBSLMM.PseudoVal pT+clump.10FCVal 0.402 0.374 0.028 2.01e-05 0.339 0.315 0.024 8.81e-02
GCSE LDpred1.Inf pT+clump.10FCVal 0.409 0.374 0.035 5.56e-09 0.337 0.315 0.021 9.35e-02
GCSE LDpred2.Inf pT+clump.10FCVal 0.413 0.374 0.039 1.47e-10 0.343 0.315 0.028 3.09e-02
GCSE lassosum.MultiPRS pT+clump.10FCVal 0.412 0.374 0.038 1.93e-02 0.357 0.315 0.042 1.21e-03
GCSE LDpred1.10FCVal pT+clump.10FCVal 0.405 0.374 0.031 1.51e-06 0.337 0.315 0.022 1.15e-01
GCSE pT+clump.MultiPRS pT+clump.10FCVal 0.382 0.374 0.008 6.48e-01 0.330 0.315 0.015 1.26e-02
GCSE LDpred2.MultiPRS pT+clump.10FCVal 0.423 0.374 0.050 2.02e-03 0.356 0.315 0.041 1.51e-03
GCSE pT+clump.10FCVal pT+clump.10FCVal 0.374 0.374 0.000 1.00e+00 0.315 0.315 0.000 1.00e+00
GCSE lassosum.PseudoVal pT+clump.10FCVal 0.316 0.374 -0.058 6.52e-08 0.273 0.315 -0.043 6.49e-02
GCSE LDpred2.10FCVal pT+clump.10FCVal 0.423 0.374 0.049 3.83e-15 0.358 0.315 0.043 8.13e-04
GCSE SBayesR.PseudoVal pT+clump.10FCVal 0.420 0.374 0.046 3.47e-13 0.350 0.315 0.035 8.78e-03
GCSE LDpred1.MultiPRS pT+clump.10FCVal 0.414 0.374 0.040 1.59e-02 0.341 0.315 0.026 4.58e-02
GCSE LDpred2.PseudoVal pT+clump.10FCVal 0.422 0.374 0.048 1.31e-14 0.358 0.315 0.043 9.82e-04
GCSE SBLUP.Inf pT+clump.10FCVal 0.412 0.374 0.038 2.31e-10 0.344 0.315 0.029 1.90e-02
GCSE LDpred1.Inf SBayesR.PseudoVal 0.409 0.420 -0.011 4.02e-03 0.337 0.350 -0.013 8.36e-02
GCSE DBSLMM.PseudoVal SBayesR.PseudoVal 0.402 0.420 -0.017 1.24e-06 0.339 0.350 -0.011 1.37e-01
GCSE lassosum.10FCVal SBayesR.PseudoVal 0.410 0.420 -0.010 5.89e-03 0.355 0.350 0.005 4.88e-01
GCSE LDpred2.MultiPRS SBayesR.PseudoVal 0.423 0.420 0.004 8.17e-01 0.356 0.350 0.006 1.85e-01
GCSE pT+clump.10FCVal SBayesR.PseudoVal 0.374 0.420 -0.046 3.47e-13 0.315 0.350 -0.035 8.78e-03
GCSE lassosum.PseudoVal SBayesR.PseudoVal 0.316 0.420 -0.104 3.50e-36 0.273 0.350 -0.077 1.01e-05
GCSE LDpred2.10FCVal SBayesR.PseudoVal 0.423 0.420 0.003 2.39e-01 0.358 0.350 0.008 8.44e-02
GCSE All.MultiPRS SBayesR.PseudoVal 0.423 0.420 0.004 8.24e-01 0.355 0.350 0.005 2.23e-01
GCSE LDpred1.MultiPRS SBayesR.PseudoVal 0.414 0.420 -0.006 6.98e-01 0.341 0.350 -0.009 2.36e-01
GCSE LDpred2.PseudoVal SBayesR.PseudoVal 0.422 0.420 0.002 3.15e-01 0.358 0.350 0.008 7.45e-02
GCSE SBLUP.Inf SBayesR.PseudoVal 0.412 0.420 -0.008 2.46e-02 0.344 0.350 -0.006 4.58e-01
GCSE pT+clump.MultiPRS SBayesR.PseudoVal 0.382 0.420 -0.038 1.92e-02 0.330 0.350 -0.020 7.53e-02
GCSE LDpred2.Inf SBayesR.PseudoVal 0.413 0.420 -0.006 7.92e-02 0.343 0.350 -0.007 3.43e-01
GCSE lassosum.MultiPRS SBayesR.PseudoVal 0.412 0.420 -0.008 6.05e-01 0.357 0.350 0.007 2.72e-01
GCSE LDpred1.10FCVal SBayesR.PseudoVal 0.405 0.420 -0.014 7.00e-04 0.337 0.350 -0.013 1.53e-01
GCSE SBayesR.PseudoVal SBayesR.PseudoVal 0.420 0.420 0.000 1.00e+00 0.350 0.350 0.000 1.00e+00
GCSE All.MultiPRS SBLUP.Inf 0.423 0.412 0.012 4.63e-01 0.355 0.344 0.011 7.74e-02
GCSE LDpred1.Inf SBLUP.Inf 0.409 0.412 -0.002 1.91e-01 0.337 0.344 -0.008 5.09e-02
GCSE LDpred2.Inf SBLUP.Inf 0.413 0.412 0.002 2.15e-01 0.343 0.344 -0.002 5.61e-01
GCSE DBSLMM.PseudoVal SBLUP.Inf 0.402 0.412 -0.009 2.45e-02 0.339 0.344 -0.006 5.25e-01
GCSE lassosum.10FCVal SBLUP.Inf 0.410 0.412 -0.002 7.09e-01 0.355 0.344 0.011 2.09e-01
GCSE LDpred2.MultiPRS SBLUP.Inf 0.423 0.412 0.012 4.58e-01 0.356 0.344 0.012 5.65e-02
GCSE pT+clump.10FCVal SBLUP.Inf 0.374 0.412 -0.038 2.31e-10 0.315 0.344 -0.029 1.90e-02
GCSE lassosum.PseudoVal SBLUP.Inf 0.316 0.412 -0.096 1.06e-23 0.273 0.344 -0.072 3.51e-04
GCSE LDpred2.10FCVal SBLUP.Inf 0.423 0.412 0.011 6.98e-04 0.358 0.344 0.014 3.85e-02
GCSE SBayesR.PseudoVal SBLUP.Inf 0.420 0.412 0.008 2.46e-02 0.350 0.344 0.006 4.58e-01
GCSE LDpred1.MultiPRS SBLUP.Inf 0.414 0.412 0.002 9.08e-01 0.341 0.344 -0.003 5.03e-01
GCSE LDpred2.PseudoVal SBLUP.Inf 0.422 0.412 0.010 9.20e-04 0.358 0.344 0.014 3.67e-02
GCSE SBLUP.Inf SBLUP.Inf 0.412 0.412 0.000 1.00e+00 0.344 0.344 0.000 1.00e+00
GCSE pT+clump.MultiPRS SBLUP.Inf 0.382 0.412 -0.030 6.54e-02 0.330 0.344 -0.014 2.19e-01
GCSE lassosum.MultiPRS SBLUP.Inf 0.412 0.412 0.000 9.97e-01 0.357 0.344 0.013 1.08e-01
GCSE LDpred1.10FCVal SBLUP.Inf 0.405 0.412 -0.006 1.92e-02 0.337 0.344 -0.007 2.02e-01
ADHD lassosum.PseudoVal All.MultiPRS 0.080 0.118 -0.038 3.12e-02 0.108 0.182 -0.074 4.42e-04
ADHD All.MultiPRS All.MultiPRS 0.118 0.118 0.000 1.00e+00 0.182 0.182 0.000 1.00e+00
ADHD DBSLMM.PseudoVal All.MultiPRS 0.110 0.118 -0.007 6.77e-01 0.174 0.182 -0.008 5.24e-01
ADHD LDpred1.Inf All.MultiPRS 0.111 0.118 -0.006 7.21e-01 0.188 0.182 0.006 6.21e-01
ADHD LDpred2.Inf All.MultiPRS 0.113 0.118 -0.005 7.82e-01 0.189 0.182 0.007 5.52e-01
ADHD lassosum.MultiPRS All.MultiPRS 0.117 0.118 0.000 9.86e-01 0.190 0.182 0.009 2.91e-01
ADHD LDpred1.10FCVal All.MultiPRS 0.114 0.118 -0.004 8.41e-01 0.190 0.182 0.008 4.74e-01
ADHD pT+clump.MultiPRS All.MultiPRS 0.093 0.118 -0.024 1.65e-01 0.151 0.182 -0.031 5.79e-02
ADHD LDpred2.MultiPRS All.MultiPRS 0.113 0.118 -0.005 7.82e-01 0.190 0.182 0.008 4.48e-01
ADHD pT+clump.10FCVal All.MultiPRS 0.092 0.118 -0.025 1.53e-01 0.144 0.182 -0.038 4.18e-02
ADHD lassosum.10FCVal All.MultiPRS 0.115 0.118 -0.003 8.80e-01 0.186 0.182 0.004 7.23e-01
ADHD LDpred2.10FCVal All.MultiPRS 0.117 0.118 -0.001 9.54e-01 0.187 0.182 0.005 6.28e-01
ADHD SBayesR.PseudoVal All.MultiPRS 0.111 0.118 -0.006 7.28e-01 0.189 0.182 0.007 5.57e-01
ADHD LDpred1.MultiPRS All.MultiPRS 0.113 0.118 -0.004 8.06e-01 0.190 0.182 0.008 4.63e-01
ADHD LDpred2.PseudoVal All.MultiPRS 0.114 0.118 -0.003 8.49e-01 0.190 0.182 0.008 4.55e-01
ADHD SBLUP.Inf All.MultiPRS 0.112 0.118 -0.005 7.62e-01 0.188 0.182 0.006 5.97e-01
ADHD LDpred2.MultiPRS DBSLMM.PseudoVal 0.113 0.110 0.002 8.88e-01 0.190 0.174 0.016 1.43e-01
ADHD pT+clump.10FCVal DBSLMM.PseudoVal 0.092 0.110 -0.018 6.69e-02 0.144 0.174 -0.030 1.22e-01
ADHD lassosum.PseudoVal DBSLMM.PseudoVal 0.080 0.110 -0.030 6.19e-03 0.108 0.174 -0.066 2.97e-03
ADHD All.MultiPRS DBSLMM.PseudoVal 0.118 0.110 0.007 6.77e-01 0.182 0.174 0.008 5.24e-01
ADHD LDpred1.MultiPRS DBSLMM.PseudoVal 0.113 0.110 0.003 8.65e-01 0.190 0.174 0.016 1.70e-01
ADHD LDpred2.PseudoVal DBSLMM.PseudoVal 0.114 0.110 0.004 4.90e-01 0.190 0.174 0.017 1.48e-01
ADHD DBSLMM.PseudoVal DBSLMM.PseudoVal 0.110 0.110 0.000 1.00e+00 0.174 0.174 0.000 1.00e+00
ADHD LDpred1.Inf DBSLMM.PseudoVal 0.111 0.110 0.001 8.66e-01 0.188 0.174 0.014 2.43e-01
ADHD LDpred2.Inf DBSLMM.PseudoVal 0.113 0.110 0.002 6.80e-01 0.189 0.174 0.015 1.96e-01
ADHD lassosum.MultiPRS DBSLMM.PseudoVal 0.117 0.110 0.007 6.92e-01 0.190 0.174 0.017 1.36e-01
ADHD LDpred1.10FCVal DBSLMM.PseudoVal 0.114 0.110 0.004 5.12e-01 0.190 0.174 0.016 1.63e-01
ADHD pT+clump.MultiPRS DBSLMM.PseudoVal 0.093 0.110 -0.017 3.37e-01 0.151 0.174 -0.023 1.58e-01
ADHD SBayesR.PseudoVal DBSLMM.PseudoVal 0.111 0.110 0.001 8.40e-01 0.189 0.174 0.015 2.03e-01
ADHD lassosum.10FCVal DBSLMM.PseudoVal 0.115 0.110 0.005 5.02e-01 0.186 0.174 0.012 3.69e-01
ADHD LDpred2.10FCVal DBSLMM.PseudoVal 0.117 0.110 0.006 2.74e-01 0.187 0.174 0.013 2.41e-01
ADHD SBLUP.Inf DBSLMM.PseudoVal 0.112 0.110 0.002 7.41e-01 0.188 0.174 0.014 2.26e-01
ADHD All.MultiPRS lassosum.MultiPRS 0.118 0.117 0.000 9.86e-01 0.182 0.190 -0.009 2.91e-01
ADHD LDpred1.MultiPRS lassosum.MultiPRS 0.113 0.117 -0.004 8.18e-01 0.190 0.190 -0.001 9.52e-01
ADHD LDpred1.Inf lassosum.MultiPRS 0.111 0.117 -0.006 7.37e-01 0.188 0.190 -0.003 7.91e-01
ADHD LDpred2.Inf lassosum.MultiPRS 0.113 0.117 -0.005 7.98e-01 0.189 0.190 -0.002 8.60e-01
ADHD lassosum.MultiPRS lassosum.MultiPRS 0.117 0.117 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
ADHD DBSLMM.PseudoVal lassosum.MultiPRS 0.110 0.117 -0.007 6.92e-01 0.174 0.190 -0.017 1.36e-01
ADHD lassosum.PseudoVal lassosum.MultiPRS 0.080 0.117 -0.038 3.46e-02 0.108 0.190 -0.083 3.77e-05
ADHD LDpred2.MultiPRS lassosum.MultiPRS 0.113 0.117 -0.005 2.20e-01 0.190 0.190 -0.001 9.14e-01
ADHD pT+clump.10FCVal lassosum.MultiPRS 0.092 0.117 -0.025 1.63e-01 0.144 0.190 -0.047 4.28e-03
ADHD lassosum.10FCVal lassosum.MultiPRS 0.115 0.117 -0.002 8.95e-01 0.186 0.190 -0.005 4.70e-01
ADHD LDpred2.10FCVal lassosum.MultiPRS 0.117 0.117 -0.001 9.68e-01 0.187 0.190 -0.004 6.24e-01
ADHD SBayesR.PseudoVal lassosum.MultiPRS 0.111 0.117 -0.006 7.44e-01 0.189 0.190 -0.002 8.22e-01
ADHD LDpred2.PseudoVal lassosum.MultiPRS 0.114 0.117 -0.003 8.64e-01 0.190 0.190 0.000 9.66e-01
ADHD SBLUP.Inf lassosum.MultiPRS 0.112 0.117 -0.005 7.78e-01 0.188 0.190 -0.002 7.87e-01
ADHD pT+clump.MultiPRS lassosum.MultiPRS 0.093 0.117 -0.024 1.74e-01 0.151 0.190 -0.040 3.71e-03
ADHD LDpred1.10FCVal lassosum.MultiPRS 0.114 0.117 -0.003 8.57e-01 0.190 0.190 0.000 9.62e-01
ADHD All.MultiPRS lassosum.PseudoVal 0.118 0.080 0.038 3.12e-02 0.182 0.108 0.074 4.42e-04
ADHD LDpred1.MultiPRS lassosum.PseudoVal 0.113 0.080 0.033 5.66e-02 0.190 0.108 0.082 3.66e-04
ADHD LDpred2.PseudoVal lassosum.PseudoVal 0.114 0.080 0.034 4.45e-03 0.190 0.108 0.082 5.76e-04
ADHD DBSLMM.PseudoVal lassosum.PseudoVal 0.110 0.080 0.030 6.19e-03 0.174 0.108 0.066 2.97e-03
ADHD LDpred1.Inf lassosum.PseudoVal 0.111 0.080 0.032 1.19e-02 0.188 0.108 0.080 1.27e-03
ADHD LDpred2.Inf lassosum.PseudoVal 0.113 0.080 0.033 8.85e-03 0.189 0.108 0.081 1.12e-03
ADHD lassosum.MultiPRS lassosum.PseudoVal 0.117 0.080 0.038 3.46e-02 0.190 0.108 0.083 3.77e-05
ADHD LDpred1.10FCVal lassosum.PseudoVal 0.114 0.080 0.034 4.13e-03 0.190 0.108 0.082 5.27e-04
ADHD lassosum.PseudoVal lassosum.PseudoVal 0.080 0.080 0.000 1.00e+00 0.108 0.108 0.000 1.00e+00
ADHD LDpred2.MultiPRS lassosum.PseudoVal 0.113 0.080 0.033 6.24e-02 0.190 0.108 0.082 1.21e-04
ADHD pT+clump.10FCVal lassosum.PseudoVal 0.092 0.080 0.013 3.45e-01 0.144 0.108 0.036 1.77e-01
ADHD lassosum.10FCVal lassosum.PseudoVal 0.115 0.080 0.035 3.37e-03 0.186 0.108 0.078 9.92e-04
ADHD LDpred2.10FCVal lassosum.PseudoVal 0.117 0.080 0.037 6.55e-04 0.187 0.108 0.079 1.96e-04
ADHD SBayesR.PseudoVal lassosum.PseudoVal 0.111 0.080 0.032 1.60e-03 0.189 0.108 0.081 5.62e-05
ADHD SBLUP.Inf lassosum.PseudoVal 0.112 0.080 0.032 9.88e-03 0.188 0.108 0.080 1.22e-03
ADHD pT+clump.MultiPRS lassosum.PseudoVal 0.093 0.080 0.014 4.44e-01 0.151 0.108 0.043 7.00e-02
ADHD All.MultiPRS lassosum.10FCVal 0.118 0.115 0.003 8.80e-01 0.182 0.186 -0.004 7.23e-01
ADHD LDpred1.MultiPRS lassosum.10FCVal 0.113 0.115 -0.002 9.23e-01 0.190 0.186 0.004 6.35e-01
ADHD LDpred1.Inf lassosum.10FCVal 0.111 0.115 -0.004 4.06e-01 0.188 0.186 0.002 8.15e-01
ADHD LDpred2.Inf lassosum.10FCVal 0.113 0.115 -0.002 5.91e-01 0.189 0.186 0.003 7.12e-01
ADHD lassosum.MultiPRS lassosum.10FCVal 0.117 0.115 0.002 8.95e-01 0.190 0.186 0.005 4.70e-01
ADHD DBSLMM.PseudoVal lassosum.10FCVal 0.110 0.115 -0.005 5.02e-01 0.174 0.186 -0.012 3.69e-01
ADHD lassosum.PseudoVal lassosum.10FCVal 0.080 0.115 -0.035 3.37e-03 0.108 0.186 -0.078 9.92e-04
ADHD LDpred2.MultiPRS lassosum.10FCVal 0.113 0.115 -0.002 9.02e-01 0.190 0.186 0.004 6.09e-01
ADHD pT+clump.10FCVal lassosum.10FCVal 0.092 0.115 -0.022 2.72e-03 0.144 0.186 -0.042 4.85e-03
ADHD lassosum.10FCVal lassosum.10FCVal 0.115 0.115 0.000 1.00e+00 0.186 0.186 0.000 1.00e+00
ADHD LDpred2.10FCVal lassosum.10FCVal 0.117 0.115 0.002 6.72e-01 0.187 0.186 0.001 8.81e-01
ADHD SBayesR.PseudoVal lassosum.10FCVal 0.111 0.115 -0.003 4.91e-01 0.189 0.186 0.003 7.80e-01
ADHD LDpred2.PseudoVal lassosum.10FCVal 0.114 0.115 -0.001 8.53e-01 0.190 0.186 0.004 5.63e-01
ADHD SBLUP.Inf lassosum.10FCVal 0.112 0.115 -0.003 4.75e-01 0.188 0.186 0.002 7.63e-01
ADHD pT+clump.MultiPRS lassosum.10FCVal 0.093 0.115 -0.022 2.20e-01 0.151 0.186 -0.035 1.52e-02
ADHD LDpred1.10FCVal lassosum.10FCVal 0.114 0.115 -0.001 8.32e-01 0.190 0.186 0.004 6.08e-01
ADHD DBSLMM.PseudoVal LDpred1.MultiPRS 0.110 0.113 -0.003 8.65e-01 0.174 0.190 -0.016 1.70e-01
ADHD LDpred2.MultiPRS LDpred1.MultiPRS 0.113 0.113 0.000 9.78e-01 0.190 0.190 0.000 9.65e-01
ADHD pT+clump.10FCVal LDpred1.MultiPRS 0.092 0.113 -0.021 2.36e-01 0.144 0.190 -0.046 4.68e-03
ADHD lassosum.10FCVal LDpred1.MultiPRS 0.115 0.113 0.002 9.23e-01 0.186 0.190 -0.004 6.35e-01
ADHD lassosum.PseudoVal LDpred1.MultiPRS 0.080 0.113 -0.033 5.66e-02 0.108 0.190 -0.082 3.66e-04
ADHD All.MultiPRS LDpred1.MultiPRS 0.118 0.113 0.004 8.06e-01 0.182 0.190 -0.008 4.63e-01
ADHD LDpred1.MultiPRS LDpred1.MultiPRS 0.113 0.113 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
ADHD LDpred2.PseudoVal LDpred1.MultiPRS 0.114 0.113 0.001 9.55e-01 0.190 0.190 0.000 9.72e-01
ADHD SBLUP.Inf LDpred1.MultiPRS 0.112 0.113 -0.001 9.55e-01 0.188 0.190 -0.002 7.11e-01
ADHD LDpred1.Inf LDpred1.MultiPRS 0.111 0.113 -0.002 9.11e-01 0.188 0.190 -0.002 6.32e-01
ADHD LDpred2.Inf LDpred1.MultiPRS 0.113 0.113 -0.001 9.76e-01 0.189 0.190 -0.001 8.29e-01
ADHD lassosum.MultiPRS LDpred1.MultiPRS 0.117 0.113 0.004 8.18e-01 0.190 0.190 0.001 9.52e-01
ADHD LDpred1.10FCVal LDpred1.MultiPRS 0.114 0.113 0.001 9.62e-01 0.190 0.190 0.000 9.71e-01
ADHD pT+clump.MultiPRS LDpred1.MultiPRS 0.093 0.113 -0.020 2.61e-01 0.151 0.190 -0.039 1.11e-02
ADHD SBayesR.PseudoVal LDpred1.MultiPRS 0.111 0.113 -0.002 9.19e-01 0.189 0.190 -0.001 8.57e-01
ADHD LDpred2.10FCVal LDpred1.MultiPRS 0.117 0.113 0.003 8.49e-01 0.187 0.190 -0.003 5.99e-01
ADHD All.MultiPRS LDpred1.Inf 0.118 0.111 0.006 7.21e-01 0.182 0.188 -0.006 6.21e-01
ADHD LDpred1.Inf LDpred1.Inf 0.111 0.111 0.000 1.00e+00 0.188 0.188 0.000 1.00e+00
ADHD LDpred2.Inf LDpred1.Inf 0.113 0.111 0.001 3.99e-01 0.189 0.188 0.001 7.78e-01
ADHD DBSLMM.PseudoVal LDpred1.Inf 0.110 0.111 -0.001 8.66e-01 0.174 0.188 -0.014 2.43e-01
ADHD lassosum.PseudoVal LDpred1.Inf 0.080 0.111 -0.032 1.19e-02 0.108 0.188 -0.080 1.27e-03
ADHD LDpred2.MultiPRS LDpred1.Inf 0.113 0.111 0.001 9.34e-01 0.190 0.188 0.002 7.64e-01
ADHD pT+clump.10FCVal LDpred1.Inf 0.092 0.111 -0.019 2.00e-02 0.144 0.188 -0.044 6.02e-03
ADHD lassosum.10FCVal LDpred1.Inf 0.115 0.111 0.004 4.06e-01 0.186 0.188 -0.002 8.15e-01
ADHD LDpred2.10FCVal LDpred1.Inf 0.117 0.111 0.005 1.08e-01 0.187 0.188 -0.001 8.93e-01
ADHD SBayesR.PseudoVal LDpred1.Inf 0.111 0.111 0.000 9.67e-01 0.189 0.188 0.001 9.33e-01
ADHD LDpred1.MultiPRS LDpred1.Inf 0.113 0.111 0.002 9.11e-01 0.190 0.188 0.002 6.32e-01
ADHD LDpred2.PseudoVal LDpred1.Inf 0.114 0.111 0.003 1.14e-01 0.190 0.188 0.002 5.51e-01
ADHD SBLUP.Inf LDpred1.Inf 0.112 0.111 0.001 5.89e-01 0.188 0.188 0.000 9.61e-01
ADHD pT+clump.MultiPRS LDpred1.Inf 0.093 0.111 -0.018 3.08e-01 0.151 0.188 -0.037 1.86e-02
ADHD lassosum.MultiPRS LDpred1.Inf 0.117 0.111 0.006 7.37e-01 0.190 0.188 0.003 7.91e-01
ADHD LDpred1.10FCVal LDpred1.Inf 0.114 0.111 0.003 5.98e-02 0.190 0.188 0.002 4.54e-01
ADHD LDpred1.Inf LDpred1.10FCVal 0.111 0.114 -0.003 5.98e-02 0.188 0.190 -0.002 4.54e-01
ADHD DBSLMM.PseudoVal LDpred1.10FCVal 0.110 0.114 -0.004 5.12e-01 0.174 0.190 -0.016 1.63e-01
ADHD lassosum.PseudoVal LDpred1.10FCVal 0.080 0.114 -0.034 4.13e-03 0.108 0.190 -0.082 5.27e-04
ADHD LDpred2.MultiPRS LDpred1.10FCVal 0.113 0.114 -0.001 9.41e-01 0.190 0.190 0.000 9.47e-01
ADHD pT+clump.10FCVal LDpred1.10FCVal 0.092 0.114 -0.022 7.45e-03 0.144 0.190 -0.046 4.07e-03
ADHD lassosum.10FCVal LDpred1.10FCVal 0.115 0.114 0.001 8.32e-01 0.186 0.190 -0.004 6.08e-01
ADHD LDpred2.10FCVal LDpred1.10FCVal 0.117 0.114 0.003 3.47e-01 0.187 0.190 -0.003 5.78e-01
ADHD All.MultiPRS LDpred1.10FCVal 0.118 0.114 0.004 8.41e-01 0.182 0.190 -0.008 4.74e-01
ADHD LDpred1.MultiPRS LDpred1.10FCVal 0.113 0.114 -0.001 9.62e-01 0.190 0.190 0.000 9.71e-01
ADHD LDpred2.PseudoVal LDpred1.10FCVal 0.114 0.114 0.000 9.26e-01 0.190 0.190 0.000 9.86e-01
ADHD SBLUP.Inf LDpred1.10FCVal 0.112 0.114 -0.002 3.55e-01 0.188 0.190 -0.002 6.08e-01
ADHD pT+clump.MultiPRS LDpred1.10FCVal 0.093 0.114 -0.021 2.39e-01 0.151 0.190 -0.040 1.08e-02
ADHD LDpred2.Inf LDpred1.10FCVal 0.113 0.114 -0.001 4.91e-01 0.189 0.190 -0.001 7.55e-01
ADHD lassosum.MultiPRS LDpred1.10FCVal 0.117 0.114 0.003 8.57e-01 0.190 0.190 0.000 9.62e-01
ADHD LDpred1.10FCVal LDpred1.10FCVal 0.114 0.114 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
ADHD SBayesR.PseudoVal LDpred1.10FCVal 0.111 0.114 -0.003 4.93e-01 0.189 0.190 -0.001 8.48e-01
ADHD LDpred2.MultiPRS LDpred2.MultiPRS 0.113 0.113 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
ADHD lassosum.PseudoVal LDpred2.MultiPRS 0.080 0.113 -0.033 6.24e-02 0.108 0.190 -0.082 1.21e-04
ADHD All.MultiPRS LDpred2.MultiPRS 0.118 0.113 0.005 7.82e-01 0.182 0.190 -0.008 4.48e-01
ADHD LDpred1.MultiPRS LDpred2.MultiPRS 0.113 0.113 0.000 9.78e-01 0.190 0.190 0.000 9.65e-01
ADHD DBSLMM.PseudoVal LDpred2.MultiPRS 0.110 0.113 -0.002 8.88e-01 0.174 0.190 -0.016 1.43e-01
ADHD LDpred1.Inf LDpred2.MultiPRS 0.111 0.113 -0.001 9.34e-01 0.188 0.190 -0.002 7.64e-01
ADHD LDpred2.Inf LDpred2.MultiPRS 0.113 0.113 0.000 9.98e-01 0.189 0.190 -0.001 8.62e-01
ADHD lassosum.MultiPRS LDpred2.MultiPRS 0.117 0.113 0.005 2.20e-01 0.190 0.190 0.001 9.14e-01
ADHD LDpred1.10FCVal LDpred2.MultiPRS 0.114 0.113 0.001 9.41e-01 0.190 0.190 0.000 9.47e-01
ADHD pT+clump.MultiPRS LDpred2.MultiPRS 0.093 0.113 -0.019 2.71e-01 0.151 0.190 -0.039 8.00e-03
ADHD SBayesR.PseudoVal LDpred2.MultiPRS 0.111 0.113 -0.001 9.42e-01 0.189 0.190 -0.001 8.55e-01
ADHD pT+clump.10FCVal LDpred2.MultiPRS 0.092 0.113 -0.020 2.54e-01 0.144 0.190 -0.046 4.49e-03
ADHD lassosum.10FCVal LDpred2.MultiPRS 0.115 0.113 0.002 9.02e-01 0.186 0.190 -0.004 6.09e-01
ADHD LDpred2.10FCVal LDpred2.MultiPRS 0.117 0.113 0.004 8.30e-01 0.187 0.190 -0.003 4.19e-02
ADHD LDpred2.PseudoVal LDpred2.MultiPRS 0.114 0.113 0.001 9.34e-01 0.190 0.190 0.000 9.15e-01
ADHD SBLUP.Inf LDpred2.MultiPRS 0.112 0.113 -0.001 9.77e-01 0.188 0.190 -0.002 7.53e-01
ADHD LDpred2.MultiPRS LDpred2.10FCVal 0.113 0.117 -0.004 8.30e-01 0.190 0.187 0.003 4.19e-02
ADHD pT+clump.10FCVal LDpred2.10FCVal 0.092 0.117 -0.024 3.07e-03 0.144 0.187 -0.043 7.38e-03
ADHD lassosum.PseudoVal LDpred2.10FCVal 0.080 0.117 -0.037 6.55e-04 0.108 0.187 -0.079 1.96e-04
ADHD All.MultiPRS LDpred2.10FCVal 0.118 0.117 0.001 9.54e-01 0.182 0.187 -0.005 6.28e-01
ADHD LDpred1.MultiPRS LDpred2.10FCVal 0.113 0.117 -0.003 8.49e-01 0.190 0.187 0.003 5.99e-01
ADHD LDpred2.PseudoVal LDpred2.10FCVal 0.114 0.117 -0.002 2.79e-01 0.190 0.187 0.003 4.67e-01
ADHD DBSLMM.PseudoVal LDpred2.10FCVal 0.110 0.117 -0.006 2.74e-01 0.174 0.187 -0.013 2.41e-01
ADHD LDpred1.Inf LDpred2.10FCVal 0.111 0.117 -0.005 1.08e-01 0.188 0.187 0.001 8.93e-01
ADHD LDpred2.Inf LDpred2.10FCVal 0.113 0.117 -0.004 1.77e-01 0.189 0.187 0.002 7.46e-01
ADHD lassosum.MultiPRS LDpred2.10FCVal 0.117 0.117 0.001 9.68e-01 0.190 0.187 0.004 6.24e-01
ADHD LDpred1.10FCVal LDpred2.10FCVal 0.114 0.117 -0.003 3.47e-01 0.190 0.187 0.003 5.78e-01
ADHD pT+clump.MultiPRS LDpred2.10FCVal 0.093 0.117 -0.023 1.87e-01 0.151 0.187 -0.036 1.36e-02
ADHD SBayesR.PseudoVal LDpred2.10FCVal 0.111 0.117 -0.005 1.09e-01 0.189 0.187 0.002 7.99e-01
ADHD lassosum.10FCVal LDpred2.10FCVal 0.115 0.117 -0.002 6.72e-01 0.186 0.187 -0.001 8.81e-01
ADHD LDpred2.10FCVal LDpred2.10FCVal 0.117 0.117 0.000 1.00e+00 0.187 0.187 0.000 1.00e+00
ADHD SBLUP.Inf LDpred2.10FCVal 0.112 0.117 -0.004 1.38e-01 0.188 0.187 0.001 8.53e-01
ADHD LDpred2.MultiPRS LDpred2.PseudoVal 0.113 0.114 -0.001 9.34e-01 0.190 0.190 0.000 9.15e-01
ADHD lassosum.PseudoVal LDpred2.PseudoVal 0.080 0.114 -0.034 4.45e-03 0.108 0.190 -0.082 5.76e-04
ADHD All.MultiPRS LDpred2.PseudoVal 0.118 0.114 0.003 8.49e-01 0.182 0.190 -0.008 4.55e-01
ADHD LDpred1.MultiPRS LDpred2.PseudoVal 0.113 0.114 -0.001 9.55e-01 0.190 0.190 0.000 9.72e-01
ADHD DBSLMM.PseudoVal LDpred2.PseudoVal 0.110 0.114 -0.004 4.90e-01 0.174 0.190 -0.017 1.48e-01
ADHD LDpred1.Inf LDpred2.PseudoVal 0.111 0.114 -0.003 1.14e-01 0.188 0.190 -0.002 5.51e-01
ADHD LDpred2.Inf LDpred2.PseudoVal 0.113 0.114 -0.002 4.74e-02 0.189 0.190 -0.001 3.99e-01
ADHD lassosum.MultiPRS LDpred2.PseudoVal 0.117 0.114 0.003 8.64e-01 0.190 0.190 0.000 9.66e-01
ADHD LDpred1.10FCVal LDpred2.PseudoVal 0.114 0.114 0.000 9.26e-01 0.190 0.190 0.000 9.86e-01
ADHD pT+clump.MultiPRS LDpred2.PseudoVal 0.093 0.114 -0.021 2.36e-01 0.151 0.190 -0.040 9.04e-03
ADHD SBayesR.PseudoVal LDpred2.PseudoVal 0.111 0.114 -0.003 4.92e-01 0.189 0.190 -0.002 8.48e-01
ADHD pT+clump.10FCVal LDpred2.PseudoVal 0.092 0.114 -0.022 6.31e-03 0.144 0.190 -0.046 3.18e-03
ADHD lassosum.10FCVal LDpred2.PseudoVal 0.115 0.114 0.001 8.53e-01 0.186 0.190 -0.004 5.63e-01
ADHD LDpred2.10FCVal LDpred2.PseudoVal 0.117 0.114 0.002 2.79e-01 0.187 0.190 -0.003 4.67e-01
ADHD LDpred2.PseudoVal LDpred2.PseudoVal 0.114 0.114 0.000 1.00e+00 0.190 0.190 0.000 1.00e+00
ADHD SBLUP.Inf LDpred2.PseudoVal 0.112 0.114 -0.002 8.47e-02 0.188 0.190 -0.002 3.58e-01
ADHD DBSLMM.PseudoVal LDpred2.Inf 0.110 0.113 -0.002 6.80e-01 0.174 0.189 -0.015 1.96e-01
ADHD LDpred2.MultiPRS LDpred2.Inf 0.113 0.113 0.000 9.98e-01 0.190 0.189 0.001 8.62e-01
ADHD pT+clump.10FCVal LDpred2.Inf 0.092 0.113 -0.020 1.19e-02 0.144 0.189 -0.045 4.49e-03
ADHD lassosum.10FCVal LDpred2.Inf 0.115 0.113 0.002 5.91e-01 0.186 0.189 -0.003 7.12e-01
ADHD lassosum.PseudoVal LDpred2.Inf 0.080 0.113 -0.033 8.85e-03 0.108 0.189 -0.081 1.12e-03
ADHD All.MultiPRS LDpred2.Inf 0.118 0.113 0.005 7.82e-01 0.182 0.189 -0.007 5.52e-01
ADHD LDpred1.MultiPRS LDpred2.Inf 0.113 0.113 0.001 9.76e-01 0.190 0.189 0.001 8.29e-01
ADHD LDpred2.PseudoVal LDpred2.Inf 0.114 0.113 0.002 4.74e-02 0.190 0.189 0.001 3.99e-01
ADHD SBLUP.Inf LDpred2.Inf 0.112 0.113 0.000 6.55e-01 0.188 0.189 -0.001 6.98e-01
ADHD LDpred1.Inf LDpred2.Inf 0.111 0.113 -0.001 3.99e-01 0.188 0.189 -0.001 7.78e-01
ADHD LDpred2.Inf LDpred2.Inf 0.113 0.113 0.000 1.00e+00 0.189 0.189 0.000 1.00e+00
ADHD lassosum.MultiPRS LDpred2.Inf 0.117 0.113 0.005 7.98e-01 0.190 0.189 0.002 8.60e-01
ADHD LDpred1.10FCVal LDpred2.Inf 0.114 0.113 0.001 4.91e-01 0.190 0.189 0.001 7.55e-01
ADHD pT+clump.MultiPRS LDpred2.Inf 0.093 0.113 -0.019 2.72e-01 0.151 0.189 -0.038 1.42e-02
ADHD SBayesR.PseudoVal LDpred2.Inf 0.111 0.113 -0.001 7.83e-01 0.189 0.189 0.000 9.80e-01
ADHD LDpred2.10FCVal LDpred2.Inf 0.117 0.113 0.004 1.77e-01 0.187 0.189 -0.002 7.46e-01
ADHD All.MultiPRS pT+clump.MultiPRS 0.118 0.093 0.024 1.65e-01 0.182 0.151 0.031 5.79e-02
ADHD LDpred1.MultiPRS pT+clump.MultiPRS 0.113 0.093 0.020 2.61e-01 0.190 0.151 0.039 1.11e-02
ADHD LDpred2.PseudoVal pT+clump.MultiPRS 0.114 0.093 0.021 2.36e-01 0.190 0.151 0.040 9.04e-03
ADHD DBSLMM.PseudoVal pT+clump.MultiPRS 0.110 0.093 0.017 3.37e-01 0.174 0.151 0.023 1.58e-01
ADHD LDpred1.Inf pT+clump.MultiPRS 0.111 0.093 0.018 3.08e-01 0.188 0.151 0.037 1.86e-02
ADHD LDpred2.Inf pT+clump.MultiPRS 0.113 0.093 0.019 2.72e-01 0.189 0.151 0.038 1.42e-02
ADHD lassosum.MultiPRS pT+clump.MultiPRS 0.117 0.093 0.024 1.74e-01 0.190 0.151 0.040 3.71e-03
ADHD LDpred1.10FCVal pT+clump.MultiPRS 0.114 0.093 0.021 2.39e-01 0.190 0.151 0.040 1.08e-02
ADHD lassosum.PseudoVal pT+clump.MultiPRS 0.080 0.093 -0.014 4.44e-01 0.108 0.151 -0.043 7.00e-02
ADHD LDpred2.MultiPRS pT+clump.MultiPRS 0.113 0.093 0.019 2.71e-01 0.190 0.151 0.039 8.00e-03
ADHD pT+clump.10FCVal pT+clump.MultiPRS 0.092 0.093 -0.001 9.62e-01 0.144 0.151 -0.007 3.29e-01
ADHD lassosum.10FCVal pT+clump.MultiPRS 0.115 0.093 0.022 2.20e-01 0.186 0.151 0.035 1.52e-02
ADHD LDpred2.10FCVal pT+clump.MultiPRS 0.117 0.093 0.023 1.87e-01 0.187 0.151 0.036 1.36e-02
ADHD SBayesR.PseudoVal pT+clump.MultiPRS 0.111 0.093 0.018 3.03e-01 0.189 0.151 0.038 1.58e-02
ADHD SBLUP.Inf pT+clump.MultiPRS 0.112 0.093 0.019 2.83e-01 0.188 0.151 0.038 1.28e-02
ADHD pT+clump.MultiPRS pT+clump.MultiPRS 0.093 0.093 0.000 1.00e+00 0.151 0.151 0.000 1.00e+00
ADHD lassosum.PseudoVal pT+clump.10FCVal 0.080 0.092 -0.013 3.45e-01 0.108 0.144 -0.036 1.77e-01
ADHD All.MultiPRS pT+clump.10FCVal 0.118 0.092 0.025 1.53e-01 0.182 0.144 0.038 4.18e-02
ADHD DBSLMM.PseudoVal pT+clump.10FCVal 0.110 0.092 0.018 6.69e-02 0.174 0.144 0.030 1.22e-01
ADHD LDpred1.Inf pT+clump.10FCVal 0.111 0.092 0.019 2.00e-02 0.188 0.144 0.044 6.02e-03
ADHD LDpred2.Inf pT+clump.10FCVal 0.113 0.092 0.020 1.19e-02 0.189 0.144 0.045 4.49e-03
ADHD lassosum.MultiPRS pT+clump.10FCVal 0.117 0.092 0.025 1.63e-01 0.190 0.144 0.047 4.28e-03
ADHD LDpred1.10FCVal pT+clump.10FCVal 0.114 0.092 0.022 7.45e-03 0.190 0.144 0.046 4.07e-03
ADHD pT+clump.MultiPRS pT+clump.10FCVal 0.093 0.092 0.001 9.62e-01 0.151 0.144 0.007 3.29e-01
ADHD LDpred2.MultiPRS pT+clump.10FCVal 0.113 0.092 0.020 2.54e-01 0.190 0.144 0.046 4.49e-03
ADHD pT+clump.10FCVal pT+clump.10FCVal 0.092 0.092 0.000 1.00e+00 0.144 0.144 0.000 1.00e+00
ADHD lassosum.10FCVal pT+clump.10FCVal 0.115 0.092 0.022 2.72e-03 0.186 0.144 0.042 4.85e-03
ADHD LDpred2.10FCVal pT+clump.10FCVal 0.117 0.092 0.024 3.07e-03 0.187 0.144 0.043 7.38e-03
ADHD SBayesR.PseudoVal pT+clump.10FCVal 0.111 0.092 0.019 3.36e-02 0.189 0.144 0.045 1.09e-02
ADHD LDpred1.MultiPRS pT+clump.10FCVal 0.113 0.092 0.021 2.36e-01 0.190 0.144 0.046 4.68e-03
ADHD LDpred2.PseudoVal pT+clump.10FCVal 0.114 0.092 0.022 6.31e-03 0.190 0.144 0.046 3.18e-03
ADHD SBLUP.Inf pT+clump.10FCVal 0.112 0.092 0.020 1.02e-02 0.188 0.144 0.044 3.63e-03
ADHD LDpred1.Inf SBayesR.PseudoVal 0.111 0.111 0.000 9.67e-01 0.188 0.189 -0.001 9.33e-01
ADHD DBSLMM.PseudoVal SBayesR.PseudoVal 0.110 0.111 -0.001 8.40e-01 0.174 0.189 -0.015 2.03e-01
ADHD lassosum.PseudoVal SBayesR.PseudoVal 0.080 0.111 -0.032 1.60e-03 0.108 0.189 -0.081 5.62e-05
ADHD LDpred2.MultiPRS SBayesR.PseudoVal 0.113 0.111 0.001 9.42e-01 0.190 0.189 0.001 8.55e-01
ADHD pT+clump.10FCVal SBayesR.PseudoVal 0.092 0.111 -0.019 3.36e-02 0.144 0.189 -0.045 1.09e-02
ADHD lassosum.10FCVal SBayesR.PseudoVal 0.115 0.111 0.003 4.91e-01 0.186 0.189 -0.003 7.80e-01
ADHD LDpred2.10FCVal SBayesR.PseudoVal 0.117 0.111 0.005 1.09e-01 0.187 0.189 -0.002 7.99e-01
ADHD All.MultiPRS SBayesR.PseudoVal 0.118 0.111 0.006 7.28e-01 0.182 0.189 -0.007 5.57e-01
ADHD LDpred1.MultiPRS SBayesR.PseudoVal 0.113 0.111 0.002 9.19e-01 0.190 0.189 0.001 8.57e-01
ADHD LDpred2.PseudoVal SBayesR.PseudoVal 0.114 0.111 0.003 4.92e-01 0.190 0.189 0.002 8.48e-01
ADHD SBLUP.Inf SBayesR.PseudoVal 0.112 0.111 0.001 8.64e-01 0.188 0.189 -0.001 9.50e-01
ADHD pT+clump.MultiPRS SBayesR.PseudoVal 0.093 0.111 -0.018 3.03e-01 0.151 0.189 -0.038 1.58e-02
ADHD LDpred2.Inf SBayesR.PseudoVal 0.113 0.111 0.001 7.83e-01 0.189 0.189 0.000 9.80e-01
ADHD lassosum.MultiPRS SBayesR.PseudoVal 0.117 0.111 0.006 7.44e-01 0.190 0.189 0.002 8.22e-01
ADHD LDpred1.10FCVal SBayesR.PseudoVal 0.114 0.111 0.003 4.93e-01 0.190 0.189 0.001 8.48e-01
ADHD SBayesR.PseudoVal SBayesR.PseudoVal 0.111 0.111 0.000 1.00e+00 0.189 0.189 0.000 1.00e+00
ADHD All.MultiPRS SBLUP.Inf 0.118 0.112 0.005 7.62e-01 0.182 0.188 -0.006 5.97e-01
ADHD LDpred1.Inf SBLUP.Inf 0.111 0.112 -0.001 5.89e-01 0.188 0.188 0.000 9.61e-01
ADHD LDpred2.Inf SBLUP.Inf 0.113 0.112 0.000 6.55e-01 0.189 0.188 0.001 6.98e-01
ADHD DBSLMM.PseudoVal SBLUP.Inf 0.110 0.112 -0.002 7.41e-01 0.174 0.188 -0.014 2.26e-01
ADHD lassosum.PseudoVal SBLUP.Inf 0.080 0.112 -0.032 9.88e-03 0.108 0.188 -0.080 1.22e-03
ADHD LDpred2.MultiPRS SBLUP.Inf 0.113 0.112 0.001 9.77e-01 0.190 0.188 0.002 7.53e-01
ADHD pT+clump.10FCVal SBLUP.Inf 0.092 0.112 -0.020 1.02e-02 0.144 0.188 -0.044 3.63e-03
ADHD lassosum.10FCVal SBLUP.Inf 0.115 0.112 0.003 4.75e-01 0.186 0.188 -0.002 7.63e-01
ADHD LDpred2.10FCVal SBLUP.Inf 0.117 0.112 0.004 1.38e-01 0.187 0.188 -0.001 8.53e-01
ADHD SBayesR.PseudoVal SBLUP.Inf 0.111 0.112 -0.001 8.64e-01 0.189 0.188 0.001 9.50e-01
ADHD LDpred1.MultiPRS SBLUP.Inf 0.113 0.112 0.001 9.55e-01 0.190 0.188 0.002 7.11e-01
ADHD LDpred2.PseudoVal SBLUP.Inf 0.114 0.112 0.002 8.47e-02 0.190 0.188 0.002 3.58e-01
ADHD SBLUP.Inf SBLUP.Inf 0.112 0.112 0.000 1.00e+00 0.188 0.188 0.000 1.00e+00
ADHD pT+clump.MultiPRS SBLUP.Inf 0.093 0.112 -0.019 2.83e-01 0.151 0.188 -0.038 1.28e-02
ADHD lassosum.MultiPRS SBLUP.Inf 0.117 0.112 0.005 7.78e-01 0.190 0.188 0.002 7.87e-01
ADHD LDpred1.10FCVal SBLUP.Inf 0.114 0.112 0.002 3.55e-01 0.190 0.188 0.002 6.08e-01

Show cross-validation differences between methods

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation differences between methods

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation


4.3 Further analysis of GCTB

Show SBayesR approaches used

Information used to avoid convergence issues in SBayesR
GWAS Reference Process h2 (SE) perVariant Complete Converge Used
DEPR06 1KG Original 0.035 (0.002) TRUE TRUE TRUE TRUE
DEPR06 1KG P<0.4 0.092 (0.003) TRUE TRUE TRUE FALSE
DEPR06 1KG v2.03 0.035 (0.002) TRUE TRUE TRUE FALSE
DEPR06 1KG v2.03 robust 0.043 (0.003) TRUE TRUE TRUE FALSE
DEPR06 UKB Original 0.057 (0.002) TRUE TRUE TRUE TRUE
DEPR06 UKB P<0.4 0.138 (0.003) TRUE TRUE TRUE FALSE
DEPR06 UKB v2.03 0.057 (0.002) TRUE TRUE TRUE FALSE
DEPR06 UKB v2.03 robust 0.057 (0.002) TRUE TRUE TRUE FALSE
DEPR06 GCTB Original 0.058 (0.002) TRUE TRUE TRUE TRUE
DEPR06 GCTB P<0.4 0.14 (0.003) TRUE TRUE TRUE FALSE
DEPR06 GCTB v2.03 0.059 (0.002) TRUE TRUE TRUE FALSE
DEPR06 GCTB v2.03 robust 0.058 (0.002) TRUE TRUE TRUE FALSE
COLL01 1KG Original 0.113 (0.007) FALSE TRUE TRUE TRUE
COLL01 1KG P<0.4 0.343 (0.01) FALSE TRUE TRUE FALSE
COLL01 1KG v2.03 0.115 (0.007) FALSE TRUE TRUE FALSE
COLL01 1KG v2.03 robust 0.112 (0.031) FALSE TRUE TRUE FALSE
COLL01 UKB Original 0.162 (0.007) FALSE TRUE TRUE TRUE
COLL01 UKB P<0.4 0.504 (0.013) FALSE TRUE TRUE FALSE
COLL01 UKB v2.03 0.165 (0.008) FALSE TRUE TRUE FALSE
COLL01 UKB v2.03 robust 0.141 (0.006) FALSE TRUE TRUE FALSE
COLL01 GCTB Original 0.168 (0.007) FALSE TRUE TRUE TRUE
COLL01 GCTB P<0.4 0.531 (0.014) FALSE TRUE TRUE FALSE
COLL01 GCTB v2.03 0.171 (0.007) FALSE TRUE TRUE FALSE
COLL01 GCTB v2.03 robust 0.146 (0.007) FALSE TRUE TRUE FALSE
BODY04 1KG Original 0.248 (0.059) TRUE TRUE TRUE TRUE
BODY04 1KG P<0.4 0.192 (0.016) TRUE TRUE TRUE FALSE
BODY04 1KG v2.03 0.255 (0.064) TRUE TRUE TRUE FALSE
BODY04 1KG v2.03 robust 0.048 (0.003) TRUE TRUE TRUE FALSE
BODY04 UKB Original 1.397 (0.68) TRUE TRUE FALSE FALSE
BODY04 UKB P<0.4 1.048 (0.42) TRUE TRUE TRUE TRUE
BODY04 UKB v2.03 1.399 (0.68) TRUE TRUE FALSE FALSE
BODY04 UKB v2.03 robust 0.061 (0.002) TRUE TRUE TRUE FALSE
BODY04 GCTB Original 0.92 (0.43) TRUE TRUE TRUE TRUE
BODY04 GCTB P<0.4 0.701 (0.265) TRUE TRUE TRUE FALSE
BODY04 GCTB v2.03 0.957 (0.461) TRUE TRUE TRUE FALSE
BODY04 GCTB v2.03 robust 0.059 (0.002) TRUE TRUE TRUE FALSE
HEIG03 1KG Original 0.718 (0.109) TRUE TRUE TRUE TRUE
HEIG03 1KG P<0.4 0.56 (0.057) TRUE TRUE TRUE FALSE
HEIG03 1KG v2.03 0.719 (0.11) TRUE TRUE TRUE FALSE
HEIG03 1KG v2.03 robust 0.251 (0.005) TRUE TRUE TRUE FALSE
HEIG03 UKB Original 3.876 (1.436) TRUE TRUE FALSE FALSE
HEIG03 UKB P<0.4 3.163 (1.174) TRUE TRUE FALSE FALSE
HEIG03 UKB v2.03 3.877 (1.437) TRUE TRUE FALSE FALSE
HEIG03 UKB v2.03 robust 0.433 (0.004) TRUE TRUE TRUE TRUE
HEIG03 GCTB Original 2.806 (1.142) TRUE FALSE FALSE FALSE
HEIG03 GCTB P<0.4 2.424 (0.887) TRUE FALSE FALSE FALSE
HEIG03 GCTB v2.03 2.958 (1.157) TRUE TRUE FALSE FALSE
HEIG03 GCTB v2.03 robust 0.44 (0.004) TRUE TRUE TRUE TRUE
DIAB05 1KG Original 0.065 (0.005) TRUE TRUE TRUE TRUE
DIAB05 1KG P<0.4 0.225 (0.007) TRUE TRUE TRUE FALSE
DIAB05 1KG v2.03 0.066 (0.006) TRUE TRUE TRUE FALSE
DIAB05 1KG v2.03 robust 0.059 (0.006) TRUE TRUE TRUE FALSE
DIAB05 UKB Original 0.093 (0.005) TRUE TRUE TRUE TRUE
DIAB05 UKB P<0.4 0.34 (0.009) TRUE TRUE TRUE FALSE
DIAB05 UKB v2.03 0.094 (0.005) TRUE TRUE TRUE FALSE
DIAB05 UKB v2.03 robust 0.084 (0.005) TRUE TRUE TRUE FALSE
DIAB05 GCTB Original 0.092 (0.005) TRUE TRUE TRUE TRUE
DIAB05 GCTB P<0.4 0.344 (0.009) TRUE TRUE TRUE FALSE
DIAB05 GCTB v2.03 0.093 (0.005) TRUE TRUE TRUE FALSE
DIAB05 GCTB v2.03 robust 0.085 (0.005) TRUE TRUE TRUE FALSE
COAD01 1KG Original 0.033 (0.003) FALSE TRUE TRUE TRUE
COAD01 1KG P<0.4 0.156 (0.005) FALSE TRUE TRUE FALSE
COAD01 1KG v2.03 0.036 (0.003) FALSE TRUE TRUE FALSE
COAD01 1KG v2.03 robust 0.035 (0.004) FALSE TRUE TRUE FALSE
COAD01 UKB Original 0.077 (0.019) FALSE TRUE TRUE TRUE
COAD01 UKB P<0.4 0.247 (0.02) FALSE TRUE TRUE FALSE
COAD01 UKB v2.03 0.078 (0.019) FALSE TRUE TRUE FALSE
COAD01 UKB v2.03 robust 0.043 (0.003) FALSE TRUE TRUE FALSE
COAD01 GCTB Original 0.077 (0.021) FALSE TRUE TRUE TRUE
COAD01 GCTB P<0.4 0.232 (0.007) FALSE TRUE TRUE FALSE
COAD01 GCTB v2.03 0.072 (0.016) FALSE TRUE TRUE FALSE
COAD01 GCTB v2.03 robust 0.042 (0.003) FALSE TRUE TRUE FALSE
CROH01 1KG Original 0.774 (0.246) FALSE TRUE TRUE TRUE
CROH01 1KG P<0.4 1.468 (0.047) FALSE TRUE FALSE FALSE
CROH01 1KG v2.03 0.905 (0.301) FALSE TRUE TRUE FALSE
CROH01 1KG v2.03 robust 0.389 (0.042) FALSE TRUE TRUE FALSE
CROH01 UKB Original 0.64 (0.141) FALSE FALSE FALSE FALSE
CROH01 UKB P<0.4 2.073 (0.058) FALSE TRUE FALSE FALSE
CROH01 UKB v2.03 0.589 (0.056) FALSE TRUE TRUE TRUE
CROH01 UKB v2.03 robust 0.476 (0.031) FALSE TRUE TRUE FALSE
CROH01 GCTB Original 0.835 (0.12) FALSE FALSE FALSE FALSE
CROH01 GCTB P<0.4 2.12 (0.057) FALSE TRUE FALSE FALSE
CROH01 GCTB v2.03 0.933 (0.164) FALSE TRUE TRUE TRUE
CROH01 GCTB v2.03 robust 0.485 (0.027) FALSE TRUE TRUE FALSE
SCLE03 1KG Original 0.689 (0.077) FALSE TRUE TRUE TRUE
SCLE03 1KG P<0.4 1.345 (0.051) FALSE TRUE FALSE FALSE
SCLE03 1KG v2.03 0.713 (0.085) FALSE TRUE TRUE FALSE
SCLE03 1KG v2.03 robust 0.239 (0.024) FALSE TRUE TRUE FALSE
SCLE03 UKB Original 0.741 (0.094) FALSE FALSE FALSE FALSE
SCLE03 UKB P<0.4 1.784 (0.049) FALSE FALSE FALSE FALSE
SCLE03 UKB v2.03 0.742 (0.092) FALSE TRUE TRUE TRUE
SCLE03 UKB v2.03 robust 0.303 (0.021) FALSE TRUE TRUE FALSE
SCLE03 GCTB Original 0.767 (0.126) FALSE FALSE FALSE FALSE
SCLE03 GCTB P<0.4 1.845 (0.051) FALSE FALSE FALSE FALSE
SCLE03 GCTB v2.03 0.697 (0.08) FALSE TRUE TRUE TRUE
SCLE03 GCTB v2.03 robust 0.289 (0.022) FALSE TRUE TRUE FALSE
RHEU02 1KG Original 0.244 (0.011) FALSE TRUE TRUE TRUE
RHEU02 1KG P<0.4 0.536 (0.018) FALSE TRUE TRUE FALSE
RHEU02 1KG v2.03 0.244 (0.011) FALSE TRUE TRUE FALSE
RHEU02 1KG v2.03 robust 0.226 (0.015) FALSE TRUE TRUE FALSE
RHEU02 UKB Original 0.358 (0.021) FALSE TRUE TRUE TRUE
RHEU02 UKB P<0.4 0.778 (0.022) FALSE TRUE TRUE FALSE
RHEU02 UKB v2.03 0.365 (0.033) FALSE TRUE TRUE FALSE
RHEU02 UKB v2.03 robust 0.352 (0.016) FALSE TRUE TRUE FALSE
RHEU02 GCTB Original 0.358 (0.012) FALSE TRUE TRUE TRUE
RHEU02 GCTB P<0.4 0.787 (0.022) FALSE TRUE TRUE FALSE
RHEU02 GCTB v2.03 0.36 (0.012) FALSE TRUE TRUE FALSE
RHEU02 GCTB v2.03 robust 0.366 (0.016) FALSE TRUE TRUE FALSE
EDUC03 1KG Original 0.063 (0.002) FALSE TRUE TRUE TRUE
EDUC03 1KG P<0.4 0.093 (0.002) FALSE TRUE TRUE FALSE
EDUC03 1KG v2.03 0.063 (0.002) FALSE TRUE TRUE FALSE
EDUC03 1KG v2.03 robust 0.063 (0.002) FALSE TRUE TRUE FALSE
EDUC03 UKB Original 0.106 (0.001) FALSE TRUE TRUE TRUE
EDUC03 UKB P<0.4 0.143 (0.002) FALSE TRUE TRUE FALSE
EDUC03 UKB v2.03 0.106 (0.001) FALSE TRUE TRUE FALSE
EDUC03 UKB v2.03 robust 0.106 (0.001) FALSE TRUE TRUE FALSE
EDUC03 GCTB Original 0.108 (0.001) FALSE TRUE TRUE TRUE
EDUC03 GCTB P<0.4 0.143 (0.002) FALSE TRUE TRUE FALSE
EDUC03 GCTB v2.03 0.108 (0.001) FALSE TRUE TRUE FALSE
EDUC03 GCTB v2.03 robust 0.109 (0.001) FALSE TRUE TRUE FALSE
ADHD04 1KG Original 0.254 (0.013) FALSE TRUE TRUE TRUE
ADHD04 1KG P<0.4 0.902 (0.027) FALSE TRUE TRUE FALSE
ADHD04 1KG v2.03 0.26 (0.012) FALSE TRUE TRUE FALSE
ADHD04 1KG v2.03 robust 0.313 (0.042) FALSE TRUE TRUE FALSE
ADHD04 UKB Original 0.378 (0.016) FALSE TRUE TRUE TRUE
ADHD04 UKB P<0.4 1.274 (0.033) FALSE TRUE FALSE FALSE
ADHD04 UKB v2.03 0.385 (0.015) FALSE TRUE TRUE FALSE
ADHD04 UKB v2.03 robust 0.384 (0.015) FALSE TRUE TRUE FALSE
ADHD04 GCTB Original 0.39 (0.016) FALSE TRUE TRUE TRUE
ADHD04 GCTB P<0.4 1.295 (0.034) FALSE TRUE FALSE FALSE
ADHD04 GCTB v2.03 0.395 (0.016) FALSE TRUE TRUE FALSE
ADHD04 GCTB v2.03 robust 0.39 (0.016) FALSE TRUE TRUE FALSE
BODY11 1KG Original 0.123 (0.002) TRUE TRUE TRUE TRUE
BODY11 1KG P<0.4 0.158 (0.002) TRUE TRUE TRUE FALSE
BODY11 1KG v2.03 0.124 (0.002) TRUE TRUE TRUE FALSE
BODY11 1KG v2.03 robust 0.123 (0.003) TRUE TRUE TRUE FALSE
BODY11 UKB Original 0.213 (0.003) TRUE TRUE TRUE TRUE
BODY11 UKB P<0.4 0.251 (0.002) TRUE TRUE TRUE FALSE
BODY11 UKB v2.03 0.211 (0.002) TRUE TRUE TRUE FALSE
BODY11 UKB v2.03 robust 0.211 (0.002) TRUE TRUE TRUE FALSE
BODY11 GCTB Original 0.217 (0.003) TRUE TRUE TRUE TRUE
BODY11 GCTB P<0.4 0.253 (0.002) TRUE TRUE TRUE FALSE
BODY11 GCTB v2.03 0.217 (0.003) TRUE TRUE TRUE FALSE
BODY11 GCTB v2.03 robust 0.216 (0.002) TRUE TRUE TRUE FALSE
PRCA01 1KG Original 0.124 (0.004) FALSE TRUE TRUE TRUE
PRCA01 1KG P<0.4 0.244 (0.005) FALSE TRUE TRUE FALSE
PRCA01 1KG v2.03 0.126 (0.004) FALSE TRUE TRUE FALSE
PRCA01 1KG v2.03 robust 0.124 (0.005) FALSE TRUE TRUE FALSE
PRCA01 UKB Original 0.241 (0.021) FALSE TRUE TRUE TRUE
PRCA01 UKB P<0.4 0.351 (0.007) FALSE TRUE TRUE FALSE
PRCA01 UKB v2.03 0.242 (0.022) FALSE TRUE TRUE FALSE
PRCA01 UKB v2.03 robust 0.161 (0.004) FALSE TRUE TRUE FALSE
PRCA01 GCTB Original 0.195 (0.02) FALSE TRUE TRUE TRUE
PRCA01 GCTB P<0.4 0.357 (0.007) FALSE TRUE TRUE FALSE
PRCA01 GCTB v2.03 0.197 (0.021) FALSE TRUE TRUE FALSE
PRCA01 GCTB v2.03 robust 0.163 (0.005) FALSE TRUE TRUE FALSE
BRCA01 1KG Original 0.107 (0.003) FALSE TRUE TRUE TRUE
BRCA01 1KG P<0.4 0.209 (0.004) FALSE TRUE TRUE FALSE
BRCA01 1KG v2.03 0.107 (0.003) FALSE TRUE TRUE FALSE
BRCA01 1KG v2.03 robust 0.106 (0.004) FALSE TRUE TRUE FALSE
BRCA01 UKB Original 0.158 (0.003) FALSE TRUE TRUE TRUE
BRCA01 UKB P<0.4 0.304 (0.005) FALSE TRUE TRUE FALSE
BRCA01 UKB v2.03 0.158 (0.003) FALSE TRUE TRUE FALSE
BRCA01 UKB v2.03 robust 0.158 (0.004) FALSE TRUE TRUE FALSE
BRCA01 GCTB Original 0.16 (0.003) FALSE TRUE TRUE TRUE
BRCA01 GCTB P<0.4 0.308 (0.005) FALSE TRUE TRUE FALSE
BRCA01 GCTB v2.03 0.16 (0.003) FALSE TRUE TRUE FALSE
BRCA01 GCTB v2.03 robust 0.16 (0.004) FALSE TRUE TRUE FALSE

Compare SBayesR results

# Create a table indicating whether per variant sample size is available
Files<-c('UKBB','TEDS')
Samples<-c('UKBB','TEDS')

source('/users/k1806347/brc_scratch/Software/MyGit/GenoPred/config_used/Target_scoring.config')

for(file in 1:length(Files)){
    if(Samples[file] == 'UKBB'){
      pheno<-c('Depression','Intelligence','BMI','Height','T2D','CAD','IBD','MultiScler','RheuArth','Breast_Cancer','Prostate_Cancer')
      gwas<-c('DEPR06','COLL01','BODY04','HEIG03','DIAB05','COAD01','CROH01','SCLE03','RHEU02','BRCA01','PRCA01')
    } else {
      pheno<-c('Height21', 'BMI21', 'GCSE', 'ADHD')
      gwas<-c('HEIG03', 'BODY11', 'EDUC03', 'ADHD04')
    }

  res<-NULL

  for(i in 1:length(pheno)){
      res_eval_1KG_i<-NULL
      res_eval_1KG_P4_i<-NULL
      res_eval_1KG_GCTB_203_i<-NULL
      res_eval_1KG_GCTB_203_robust_i<-NULL
      res_eval_UKBB_i<-NULL
      res_eval_UKBB_P4_i<-NULL
      res_eval_UKBB_GCTB_203_i<-NULL
      res_eval_UKBB_GCTB_203_robust_i<-NULL
      res_eval_GCTB_i<-NULL
      res_eval_GCTB_P4_i<-NULL
      res_eval_GCTB_GCTB_203_i<-NULL
      res_eval_GCTB_GCTB_203_robust_i<-NULL

      # 1KG ref
      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_1KG_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_1KG_i<-res_eval_1KG_i[2,]
        res_eval_1KG_i$Model<-"v2.02 (Default)"
        res_eval_1KG_i$Ref<-'1KG'
      }

      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_P4.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_1KG_P4_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_P4.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_1KG_P4_i<-res_eval_1KG_P4_i[2,]
        res_eval_1KG_P4_i$Model<-"v2.02 (P<0.4)"
        res_eval_1KG_P4_i$Ref<-'1KG'
      }

      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTB_203.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_1KG_GCTB_203_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTB_203.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_1KG_GCTB_203_i<-res_eval_1KG_GCTB_203_i[2,]
        res_eval_1KG_GCTB_203_i$Model<-"v2.03 (Default)"
        res_eval_1KG_GCTB_203_i$Ref<-'1KG'
      }
      
      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTB_203_robust.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_1KG_GCTB_203_robust_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTB_203_robust.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_1KG_GCTB_203_robust_i<-res_eval_1KG_GCTB_203_robust_i[2,]
        res_eval_1KG_GCTB_203_robust_i$Model<-"v2.03 (Robust)"
        res_eval_1KG_GCTB_203_robust_i$Ref<-'1KG'
      }
      
      # UKB ref
      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_UKBB_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_UKBB_i<-res_eval_UKBB_i[2,]
        res_eval_UKBB_i$Model<-"v2.02 (Default)"
        res_eval_UKBB_i$Ref<-'UKB'
      }

      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'_P4.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_UKBB_P4_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'_P4.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_UKBB_P4_i<-res_eval_UKBB_P4_i[2,]
        res_eval_UKBB_P4_i$Model<-"v2.02 (P<0.4)"
        res_eval_UKBB_P4_i$Ref<-'UKB'
      }

      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'_GCTB_203.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_UKBB_GCTB_203_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'_GCTB_203.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_UKBB_GCTB_203_i<-res_eval_UKBB_GCTB_203_i[2,]
        res_eval_UKBB_GCTB_203_i$Model<-"v2.03 (Default)"
        res_eval_UKBB_GCTB_203_i$Ref<-'UKB'
      }

      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'_GCTB_203_robust.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_UKBB_GCTB_203_robust_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.UKBB_ref.',gwas[i],'_GCTB_203_robust.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_UKBB_GCTB_203_robust_i<-res_eval_UKBB_GCTB_203_robust_i[2,]
        res_eval_UKBB_GCTB_203_robust_i$Model<-"v2.03 (Robust)"
        res_eval_UKBB_GCTB_203_robust_i$Ref<-'UKB'
      }

      # GCTB ref
      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_GCTB_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_GCTB_i<-res_eval_GCTB_i[2,]
        res_eval_GCTB_i$Model<-"v2.02 (Default)"
        res_eval_GCTB_i$Ref<-'GCTB'
      }
  
      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref_P4.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_GCTB_P4_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref_P4.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_GCTB_P4_i<-res_eval_GCTB_P4_i[2,]
        res_eval_GCTB_P4_i$Model<-"v2.02 (P<0.4)"
        res_eval_GCTB_P4_i$Ref<-'GCTB'
      }

      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref_GCTB_203.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_GCTB_GCTB_203_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref_GCTB_203.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_GCTB_GCTB_203_i<-res_eval_GCTB_GCTB_203_i[2,]
        res_eval_GCTB_GCTB_203_i$Model<-"v2.03 (Default)"
        res_eval_GCTB_GCTB_203_i$Ref<-'GCTB'
      }

      if(file.exists(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR.pred_eval.txt'))){
        res_eval_GCTB_GCTB_203_robust_i<-read.table(paste0('/users/k1806347/brc_scratch/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/',pheno[i],'/Association_withPRSs/',Samples[file],'.w_hm3.',gwas[i],'_GCTBref_GCTB_203_robust.EUR-PRSs_SBayesR.pred_eval.txt'), header=T, stringsAsFactors=F)
        res_eval_GCTB_GCTB_203_robust_i<-res_eval_GCTB_GCTB_203_robust_i[2,]
        res_eval_GCTB_GCTB_203_robust_i$Model<-"v2.03 (Robust)"
        res_eval_GCTB_GCTB_203_robust_i$Ref<-'GCTB'
      }
          
      res_i<-do.call(rbind, list(res_eval_1KG_i,res_eval_1KG_P4_i, res_eval_1KG_GCTB_203_i,res_eval_1KG_GCTB_203_robust_i,res_eval_UKBB_i,res_eval_UKBB_P4_i,res_eval_UKBB_GCTB_203_i,res_eval_UKBB_GCTB_203_robust_i,res_eval_GCTB_i,res_eval_GCTB_P4_i,res_eval_GCTB_GCTB_203_i,res_eval_GCTB_GCTB_203_robust_i))
      res_i$Phenotype<-pheno[i]
      res_i$Cross_LiabR2<-NULL
      res_i$Indep_LiabR2<-NULL
      res_i$CrossVal_pval<-NULL
      res_i$IndepVal_pval<-NULL
      res_i$Cross_AUC<-NULL
      res_i$Indep_AUC<-NULL
      res_i$CrossVal_OR<-NULL
      res_i$IndepVal_OR<-NULL
      res_i$CrossVal_HighCI<-NULL
      res_i$IndepVal_HighCI<-NULL
      res_i$CrossVal_LowCI<-NULL
      res_i$IndepVal_LowCI<-NULL
      res_i$CrossVal_Ncas<-NULL
      res_i$IndepVal_Ncas<-NULL
      res_i$CrossVal_Ncon<-NULL
      res_i$IndepVal_Ncon<-NULL
    
      res<-rbind(res, res_i)
  }
  
  write.csv(res, paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_SBayesR_',Samples[file],'.csv'), row.names=F)
  
  res$Ref<-factor(res$Ref, levels=c('1KG','UKB','GCTB'))
  res$Model<-factor(res$Model, levels=c("v2.02 (Default)","v2.02 (P<0.4)","v2.03 (Default)","v2.03 (Robust)"))
  
  plots_CrossVal<-list()
  plots_IndepVal<-list()
  for(i in 1:length(pheno)){
    plots_CrossVal[[pheno[i]]] <- ggplot( res[res$Phenotype==pheno[i],], aes(x=Ref, y=CrossVal_R, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=CrossVal_R-CrossVal_R_SE, ymax=CrossVal_R+CrossVal_R_SE), width=.4, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res$CrossVal_R[res$Phenotype==pheno[i]])-0.05, max(res$CrossVal_R[res$Phenotype==pheno[i]])+0.05), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y')
    
    plots_IndepVal[[pheno[i]]] <- ggplot( res[res$Phenotype==pheno[i],], aes(x=Ref, y=IndepVal_R, fill=Model)) +
                          geom_bar(stat="identity", position=position_dodge(preserve = "single"), width = 0.7) +
                          geom_errorbar(aes(ymin=IndepVal_R-IndepVal_R_SE, ymax=IndepVal_R+IndepVal_R_SE), width=.4, position=position_dodge(width = 0.7, preserve = "single")) +
                          labs(y="Correlation (SE)", x='', title=pheno[i]) +
                          coord_cartesian(ylim=c(min(res$IndepVal_R[res$Phenotype==pheno[i]])-0.05, max(res$IndepVal_R[res$Phenotype==pheno[i]])+0.05), clip="on") +
                          theme_half_open() +
                                  theme(axis.text.x = element_text(angle = 45, hjust = 1)) +
                          background_grid(major = 'y', minor = 'y')
  }

  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_SBayesR_CrossVal_',Samples[file],'.png'), units='px', res=300, width=2250, height=800*ceiling(length(pheno)/2))
  print(plot_grid(plotlist=plots_CrossVal, ncol = 2))
  dev.off()

  png(paste0('/scratch/users/k1806347/Analyses/PRS_comparison/',Samples[file],'_outcomes_for_prediction/PRS_SBayesR_IndepVal_',Samples[file],'.png'), units='px', res=300, width=2250, height=800*ceiling(length(pheno)/2))
  print(plot_grid(plotlist=plots_IndepVal, ncol = 2))
  dev.off()

}

# This sensitivity analysis shows the new robust implementation of SBayesR is more reliable, though can perform worse when using the smaller 1KG Phase 3 reference. I think we should compare methods using the robust implmentation of SBayesR.

Show UKBB cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show UKBB test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show TEDS cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show TEDS test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation


4.4 Average performance

Show cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show table: UKBB (1KG ref)

Average performance in UKBB with 1KG reference
Method Model CrossVal R (SE) IndepVal R (SE)
pT+clump 10FCVal 0.155 (0.002) 0.153 (0.004)
pT+clump MultiPRS 0.175 (0.002) 0.174 (0.004)
lassosum 10FCVal 0.19 (0.002) 0.183 (0.004)
lassosum MultiPRS 0.199 (0.002) 0.194 (0.004)
lassosum PseudoVal 0.159 (0.002) 0.157 (0.004)
PRScs 10FCVal 0.19 (0.002) 0.183 (0.004)
PRScs MultiPRS 0.194 (0.002) 0.187 (0.004)
PRScs PseudoVal 0.188 (0.002) 0.182 (0.004)
SBLUP Inf 0.162 (0.002) 0.156 (0.004)
SBayesR PseudoVal 0.17 (0.002) 0.167 (0.004)
LDpred1 10FCVal 0.178 (0.002) 0.171 (0.004)
LDpred1 MultiPRS 0.181 (0.002) 0.175 (0.004)
LDpred1 Inf 0.163 (0.002) 0.156 (0.004)
LDpred2 10FCVal 0.194 (0.002) 0.187 (0.004)
LDpred2 MultiPRS 0.197 (0.002) 0.191 (0.004)
LDpred2 PseudoVal 0.155 (0.002) 0.151 (0.004)
LDpred2 Inf 0.161 (0.002) 0.155 (0.004)
DBSLMM PseudoVal 0.182 (0.002) 0.175 (0.004)
All MultiPRS 0.202 (0.002) 0.197 (0.004)

Show table: UKBB (UKBB ref)

Average performance in UKBB with UKBB reference
Method Model CrossVal R (SE) IndepVal R (SE)
pT+clump 10FCVal 0.156 (0.002) 0.152 (0.004)
pT+clump MultiPRS 0.176 (0.002) 0.174 (0.004)
lassosum 10FCVal 0.19 (0.002) 0.183 (0.004)
lassosum MultiPRS 0.198 (0.002) 0.193 (0.004)
lassosum PseudoVal 0.159 (0.002) 0.157 (0.004)
SBLUP Inf 0.162 (0.002) 0.155 (0.004)
SBayesR PseudoVal 0.181 (0.002) 0.178 (0.004)
LDpred1 10FCVal 0.177 (0.002) 0.171 (0.004)
LDpred1 MultiPRS 0.182 (0.002) 0.176 (0.004)
LDpred1 Inf 0.162 (0.002) 0.155 (0.004)
LDpred2 10FCVal 0.196 (0.002) 0.19 (0.004)
LDpred2 MultiPRS 0.199 (0.002) 0.194 (0.004)
LDpred2 PseudoVal 0.17 (0.002) 0.168 (0.004)
LDpred2 Inf 0.16 (0.002) 0.154 (0.004)
DBSLMM PseudoVal 0.183 (0.002) 0.177 (0.004)
All MultiPRS 0.202 (0.002) 0.197 (0.004)

Show table: TEDS (1KG ref)

Average performance in TEDS with 1KG reference
Method Model CrossVal R (SE) IndepVal R (SE)
pT+clump 10FCVal 0.291 (0.008) 0.279 (0.016)
pT+clump MultiPRS 0.298 (0.008) 0.293 (0.016)
lassosum 10FCVal 0.328 (0.008) 0.325 (0.016)
lassosum MultiPRS 0.332 (0.008) 0.328 (0.016)
lassosum PseudoVal 0.261 (0.008) 0.245 (0.016)
PRScs 10FCVal 0.327 (0.008) 0.327 (0.016)
PRScs MultiPRS 0.329 (0.008) 0.328 (0.016)
PRScs PseudoVal 0.322 (0.008) 0.319 (0.016)
SBLUP Inf 0.304 (0.008) 0.303 (0.016)
SBayesR PseudoVal 0.314 (0.008) 0.303 (0.016)
LDpred1 10FCVal 0.309 (0.008) 0.302 (0.016)
LDpred1 MultiPRS 0.315 (0.008) 0.308 (0.016)
LDpred1 Inf 0.311 (0.008) 0.305 (0.016)
LDpred2 10FCVal 0.33 (0.008) 0.325 (0.016)
LDpred2 MultiPRS 0.331 (0.008) 0.319 (0.016)
LDpred2 PseudoVal 0.308 (0.008) 0.303 (0.016)
LDpred2 Inf 0.308 (0.008) 0.303 (0.016)
DBSLMM PseudoVal 0.321 (0.008) 0.313 (0.016)
All MultiPRS 0.337 (0.008) 0.326 (0.016)

Show table: TEDS (UKBB ref)

Average performance in TEDS with UKBB reference
Method Model CrossVal R (SE) IndepVal R (SE)
pT+clump 10FCVal 0.292 (0.008) 0.274 (0.016)
pT+clump MultiPRS 0.3 (0.008) 0.29 (0.016)
lassosum 10FCVal 0.33 (0.008) 0.329 (0.016)
lassosum MultiPRS 0.333 (0.008) 0.332 (0.016)
lassosum PseudoVal 0.258 (0.008) 0.24 (0.016)
SBLUP Inf 0.313 (0.008) 0.309 (0.016)
SBayesR PseudoVal 0.335 (0.008) 0.336 (0.016)
LDpred1 10FCVal 0.305 (0.008) 0.305 (0.016)
LDpred1 MultiPRS 0.316 (0.008) 0.313 (0.016)
LDpred1 Inf 0.312 (0.008) 0.309 (0.016)
LDpred2 10FCVal 0.341 (0.008) 0.334 (0.016)
LDpred2 MultiPRS 0.34 (0.008) 0.337 (0.016)
LDpred2 PseudoVal 0.337 (0.008) 0.336 (0.016)
LDpred2 Inf 0.316 (0.008) 0.313 (0.016)
DBSLMM PseudoVal 0.322 (0.008) 0.317 (0.016)
All MultiPRS 0.343 (0.008) 0.334 (0.016)


4.4.1 Average performance relative to pT+clump

Show cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show by polygenicity cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show by polygenicity test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show cross-validation results with PCs regressed

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results with PCs regressed

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation


4.4.2 Average performance difference across all methods

Show cross-validation results

Predictive utility estimated using 10-fold cross-validation

Predictive utility estimated using 10-fold cross-validation

Show test-validation results

Predictive utility estimated using test set validation

Predictive utility estimated using test set validation

Show table: UKBB (1KG ref)

Average difference between methods in UKBB with 1KG reference
Reference Test CrossVal Diff CrossVal Diff (%) CrossVal Diff Z CrossVal Diff P IndepVal Diff IndepVal Diff (%) IndepVal Diff Z IndepVal Diff P
pT+clump.10FCVal pT+clump.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
pT+clump.MultiPRS pT+clump.10FCVal -0.020 -13.020 -6.724 1.77e-11 -0.021 -13.831 -9.574 1.03e-21
lassosum.10FCVal pT+clump.10FCVal -0.035 -22.615 -19.871 7.24e-88 -0.030 -19.649 -8.484 2.18e-17
lassosum.MultiPRS pT+clump.10FCVal -0.044 -28.560 -14.796 1.55e-49 -0.041 -26.861 -12.592 2.33e-36
lassosum.PseudoVal pT+clump.10FCVal -0.004 -2.616 -2.119 3.41e-02 -0.004 -2.652 -1.057 2.91e-01
PRScs.10FCVal pT+clump.10FCVal -0.036 -23.037 -19.236 1.84e-82 -0.030 -19.638 -8.054 7.98e-16
PRScs.MultiPRS pT+clump.10FCVal -0.039 -25.496 -13.216 7.11e-40 -0.034 -22.541 -9.904 3.99e-23
PRScs.PseudoVal pT+clump.10FCVal -0.034 -21.666 -18.786 9.88e-79 -0.029 -19.050 -8.098 5.59e-16
SBLUP.Inf pT+clump.10FCVal -0.008 -4.963 -3.517 4.36e-04 -0.003 -2.059 -0.720 4.72e-01
SBayesR.PseudoVal pT+clump.10FCVal -0.015 -9.829 -8.242 1.70e-16 -0.014 -9.186 -3.781 1.56e-04
LDpred1.10FCVal pT+clump.10FCVal -0.024 -15.258 -12.312 7.80e-35 -0.019 -12.165 -4.830 1.36e-06
LDpred1.MultiPRS pT+clump.10FCVal -0.027 -17.272 -8.939 3.92e-19 -0.022 -14.272 -5.782 7.40e-09
LDpred1.Inf pT+clump.10FCVal -0.008 -5.186 -3.784 1.54e-04 -0.003 -2.262 -0.812 4.17e-01
LDpred2.10FCVal pT+clump.10FCVal -0.039 -25.109 -23.022 2.79e-117 -0.034 -22.480 -10.097 5.71e-24
LDpred2.MultiPRS pT+clump.10FCVal -0.042 -27.112 -14.034 9.72e-45 -0.038 -24.631 -10.750 5.90e-27
LDpred2.PseudoVal pT+clump.10FCVal 0.000 -0.101 -0.069 9.45e-01 0.002 1.382 0.462 6.44e-01
LDpred2.Inf pT+clump.10FCVal -0.006 -3.751 -2.610 9.04e-03 -0.002 -1.185 -0.407 6.84e-01
DBSLMM.PseudoVal pT+clump.10FCVal -0.027 -17.677 -15.912 5.21e-57 -0.022 -14.656 -6.480 9.17e-11
All.MultiPRS pT+clump.10FCVal -0.047 -30.588 -15.977 1.83e-57 -0.044 -29.098 -14.192 1.02e-45
pT+clump.10FCVal pT+clump.MultiPRS 0.020 11.520 6.724 1.77e-11 0.021 12.151 9.574 1.03e-21
pT+clump.MultiPRS pT+clump.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.10FCVal pT+clump.MultiPRS -0.015 -8.490 -4.978 6.41e-07 -0.009 -5.111 -3.228 1.25e-03
lassosum.MultiPRS pT+clump.MultiPRS -0.024 -13.750 -8.081 6.40e-16 -0.020 -11.446 -8.216 2.10e-16
lassosum.PseudoVal pT+clump.MultiPRS 0.016 9.205 5.371 7.84e-08 0.017 9.821 5.233 1.66e-07
PRScs.10FCVal pT+clump.MultiPRS -0.016 -8.863 -5.197 2.02e-07 -0.009 -5.101 -3.098 1.95e-03
PRScs.MultiPRS pT+clump.MultiPRS -0.019 -11.039 -6.477 9.38e-11 -0.013 -7.652 -5.048 4.47e-07
PRScs.PseudoVal pT+clump.MultiPRS -0.013 -7.651 -4.484 7.33e-06 -0.008 -4.584 -2.758 5.82e-03
SBLUP.Inf pT+clump.MultiPRS 0.012 7.128 4.164 3.13e-05 0.018 10.342 5.236 1.64e-07
SBayesR.PseudoVal pT+clump.MultiPRS 0.005 2.823 1.650 9.90e-02 0.007 4.081 2.302 2.13e-02
LDpred1.10FCVal pT+clump.MultiPRS -0.003 -1.981 -1.159 2.46e-01 0.003 1.464 0.860 3.90e-01
LDpred1.MultiPRS pT+clump.MultiPRS -0.007 -3.762 -2.201 2.77e-02 -0.001 -0.387 -0.230 8.18e-01
LDpred1.Inf pT+clump.MultiPRS 0.012 6.931 4.049 5.13e-05 0.018 10.163 5.153 2.56e-07
LDpred2.10FCVal pT+clump.MultiPRS -0.019 -10.697 -6.274 3.52e-10 -0.013 -7.598 -4.577 4.73e-06
LDpred2.MultiPRS pT+clump.MultiPRS -0.022 -12.469 -7.324 2.41e-13 -0.017 -9.487 -5.975 2.30e-09
LDpred2.PseudoVal pT+clump.MultiPRS 0.020 11.430 6.666 2.63e-11 0.023 13.365 6.493 8.42e-11
LDpred2.Inf pT+clump.MultiPRS 0.014 8.201 4.789 1.68e-06 0.019 11.110 5.447 5.13e-08
DBSLMM.PseudoVal pT+clump.MultiPRS -0.007 -4.120 -2.413 1.58e-02 -0.001 -0.724 -0.425 6.71e-01
All.MultiPRS pT+clump.MultiPRS -0.027 -15.545 -9.134 6.58e-20 -0.023 -13.411 -10.002 1.50e-23
pT+clump.10FCVal lassosum.10FCVal 0.035 18.444 19.871 7.24e-88 0.030 16.422 8.484 2.18e-17
pT+clump.MultiPRS lassosum.10FCVal 0.015 7.825 4.978 6.41e-07 0.009 4.862 3.228 1.25e-03
lassosum.10FCVal lassosum.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.MultiPRS lassosum.10FCVal -0.009 -4.849 -3.092 1.99e-03 -0.011 -6.027 -7.878 3.34e-15
lassosum.PseudoVal lassosum.10FCVal 0.031 16.310 21.066 1.62e-98 0.026 14.206 8.831 1.04e-18
PRScs.10FCVal lassosum.10FCVal -0.001 -0.344 -0.747 4.55e-01 0.000 0.009 0.010 9.92e-01
PRScs.MultiPRS lassosum.10FCVal -0.004 -2.350 -1.501 1.33e-01 -0.004 -2.417 -2.520 1.17e-02
PRScs.PseudoVal lassosum.10FCVal 0.001 0.774 1.445 1.49e-01 0.001 0.501 0.450 6.53e-01
SBLUP.Inf lassosum.10FCVal 0.027 14.396 18.505 1.88e-76 0.027 14.702 9.096 9.39e-20
SBayesR.PseudoVal lassosum.10FCVal 0.020 10.428 11.949 6.54e-33 0.016 8.745 4.807 1.53e-06
LDpred1.10FCVal lassosum.10FCVal 0.011 6.000 9.228 2.75e-20 0.011 6.255 4.633 3.61e-06
LDpred1.MultiPRS lassosum.10FCVal 0.008 4.357 2.782 5.41e-03 0.008 4.494 3.488 4.86e-04
LDpred1.Inf lassosum.10FCVal 0.027 14.214 18.843 3.35e-79 0.027 14.532 9.266 1.93e-20
LDpred2.10FCVal lassosum.10FCVal -0.004 -2.035 -3.526 4.21e-04 -0.004 -2.366 -1.980 4.77e-02
LDpred2.MultiPRS lassosum.10FCVal -0.007 -3.668 -2.341 1.93e-02 -0.008 -4.163 -3.655 2.57e-04
LDpred2.PseudoVal lassosum.10FCVal 0.035 18.361 21.630 9.31e-104 0.032 17.578 9.951 2.49e-23
LDpred2.Inf lassosum.10FCVal 0.029 15.385 18.957 3.88e-80 0.028 15.432 9.146 5.91e-20
DBSLMM.PseudoVal lassosum.10FCVal 0.008 4.027 5.679 1.35e-08 0.008 4.174 2.823 4.76e-03
All.MultiPRS lassosum.10FCVal -0.012 -6.503 -4.192 2.76e-05 -0.014 -7.897 -7.869 3.57e-15
pT+clump.10FCVal lassosum.MultiPRS 0.044 22.215 14.796 1.55e-49 0.041 21.173 12.592 2.33e-36
pT+clump.MultiPRS lassosum.MultiPRS 0.024 12.088 8.081 6.40e-16 0.020 10.270 8.216 2.10e-16
lassosum.10FCVal lassosum.MultiPRS 0.009 4.625 3.092 1.99e-03 0.011 5.684 7.878 3.34e-15
lassosum.MultiPRS lassosum.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.PseudoVal lassosum.MultiPRS 0.040 20.181 13.452 3.00e-41 0.037 19.083 14.155 1.74e-45
PRScs.10FCVal lassosum.MultiPRS 0.009 4.296 2.872 4.08e-03 0.011 5.693 6.405 1.50e-10
PRScs.MultiPRS lassosum.MultiPRS 0.005 2.383 2.364 1.81e-02 0.007 3.405 4.748 2.05e-06
PRScs.PseudoVal lassosum.MultiPRS 0.011 5.362 3.583 3.40e-04 0.012 6.157 6.830 8.51e-12
SBLUP.Inf lassosum.MultiPRS 0.037 18.355 12.218 2.49e-34 0.038 19.551 13.030 8.30e-39
SBayesR.PseudoVal lassosum.MultiPRS 0.029 14.570 9.733 2.19e-22 0.027 13.932 9.165 4.94e-20
LDpred1.10FCVal lassosum.MultiPRS 0.021 10.347 6.901 5.15e-12 0.022 11.584 10.273 9.28e-25
LDpred1.MultiPRS lassosum.MultiPRS 0.017 8.781 7.264 3.76e-13 0.019 9.923 9.198 3.64e-20
LDpred1.Inf lassosum.MultiPRS 0.036 18.181 12.100 1.06e-33 0.038 19.390 13.424 4.40e-41
LDpred2.10FCVal lassosum.MultiPRS 0.005 2.684 1.797 7.24e-02 0.007 3.453 3.632 2.81e-04
LDpred2.MultiPRS lassosum.MultiPRS 0.002 1.126 1.039 2.99e-01 0.003 1.758 2.019 4.34e-02
LDpred2.PseudoVal lassosum.MultiPRS 0.044 22.137 14.727 4.31e-49 0.043 22.263 13.892 7.06e-44
LDpred2.Inf lassosum.MultiPRS 0.038 19.298 12.843 9.36e-38 0.039 20.240 12.884 5.53e-38
DBSLMM.PseudoVal lassosum.MultiPRS 0.017 8.466 5.653 1.58e-08 0.019 9.621 8.448 2.96e-17
All.MultiPRS lassosum.MultiPRS -0.003 -1.577 -1.392 1.64e-01 -0.003 -1.763 -2.904 3.68e-03
pT+clump.10FCVal lassosum.PseudoVal 0.004 2.549 2.119 3.41e-02 0.004 2.583 1.057 2.91e-01
pT+clump.MultiPRS lassosum.PseudoVal -0.016 -10.139 -5.371 7.84e-08 -0.017 -10.891 -5.233 1.66e-07
lassosum.10FCVal lassosum.PseudoVal -0.031 -19.489 -21.066 1.62e-98 -0.026 -16.559 -8.831 1.04e-18
lassosum.MultiPRS lassosum.PseudoVal -0.040 -25.283 -13.452 3.00e-41 -0.037 -23.584 -14.155 1.74e-45
lassosum.PseudoVal lassosum.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
PRScs.10FCVal lassosum.PseudoVal -0.032 -19.901 -19.392 9.04e-84 -0.026 -16.548 -7.976 1.51e-15
PRScs.MultiPRS lassosum.PseudoVal -0.035 -22.297 -11.869 1.71e-32 -0.030 -19.376 -10.910 1.03e-27
PRScs.PseudoVal lassosum.PseudoVal -0.029 -18.565 -20.610 2.25e-94 -0.025 -15.974 -8.784 1.58e-18
SBLUP.Inf lassosum.PseudoVal -0.004 -2.288 -1.715 8.63e-02 0.001 0.578 0.214 8.30e-01
SBayesR.PseudoVal lassosum.PseudoVal -0.011 -7.029 -6.858 6.99e-12 -0.010 -6.366 -3.061 2.21e-03
LDpred1.10FCVal lassosum.PseudoVal -0.020 -12.320 -12.368 3.90e-35 -0.015 -9.267 -4.616 3.91e-06
LDpred1.MultiPRS lassosum.PseudoVal -0.023 -14.283 -7.599 2.98e-14 -0.018 -11.320 -5.600 2.15e-08
LDpred1.Inf lassosum.PseudoVal -0.004 -2.505 -1.949 5.13e-02 0.001 0.379 0.146 8.84e-01
LDpred2.10FCVal lassosum.PseudoVal -0.035 -21.920 -24.441 6.26e-132 -0.030 -19.316 -10.639 1.96e-26
LDpred2.MultiPRS lassosum.PseudoVal -0.038 -23.872 -12.691 6.67e-37 -0.034 -21.411 -11.505 1.24e-30
LDpred2.PseudoVal lassosum.PseudoVal 0.004 2.450 1.918 5.52e-02 0.006 3.930 1.520 1.29e-01
LDpred2.Inf lassosum.PseudoVal -0.002 -1.106 -0.817 4.14e-01 0.002 1.429 0.521 6.02e-01
DBSLMM.PseudoVal lassosum.PseudoVal -0.023 -14.677 -14.968 1.19e-50 -0.018 -11.694 -5.877 4.17e-09
All.MultiPRS lassosum.PseudoVal -0.043 -27.259 -14.635 1.68e-48 -0.040 -25.763 -14.291 2.50e-46
pT+clump.10FCVal PRScs.10FCVal 0.036 18.724 19.236 1.84e-82 0.030 16.415 8.054 7.98e-16
pT+clump.MultiPRS PRScs.10FCVal 0.016 8.142 5.197 2.02e-07 0.009 4.854 3.098 1.95e-03
lassosum.10FCVal PRScs.10FCVal 0.001 0.343 0.747 4.55e-01 0.000 -0.009 -0.010 9.92e-01
lassosum.MultiPRS PRScs.10FCVal -0.009 -4.489 -2.872 4.08e-03 -0.011 -6.037 -6.405 1.50e-10
lassosum.PseudoVal PRScs.10FCVal 0.032 16.598 19.392 9.04e-84 0.026 14.198 7.976 1.51e-15
PRScs.10FCVal PRScs.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
PRScs.MultiPRS PRScs.10FCVal -0.004 -1.999 -1.281 2.00e-01 -0.004 -2.427 -4.123 3.75e-05
PRScs.PseudoVal PRScs.10FCVal 0.002 1.114 2.797 5.16e-03 0.001 0.492 0.593 5.54e-01
SBLUP.Inf PRScs.10FCVal 0.028 14.690 22.036 1.30e-107 0.027 14.694 10.594 3.19e-26
SBayesR.PseudoVal PRScs.10FCVal 0.020 10.735 12.128 7.48e-34 0.016 8.736 4.712 2.45e-06
LDpred1.10FCVal PRScs.10FCVal 0.012 6.322 10.950 6.62e-28 0.011 6.247 5.219 1.80e-07
LDpred1.MultiPRS PRScs.10FCVal 0.009 4.686 3.002 2.68e-03 0.008 4.485 3.899 9.66e-05
LDpred1.Inf PRScs.10FCVal 0.028 14.508 22.021 1.81e-107 0.027 14.524 10.615 2.54e-26
LDpred2.10FCVal PRScs.10FCVal -0.003 -1.684 -2.912 3.59e-03 -0.004 -2.375 -1.982 4.75e-02
LDpred2.MultiPRS PRScs.10FCVal -0.006 -3.312 -2.121 3.39e-02 -0.008 -4.173 -3.855 1.16e-04
LDpred2.PseudoVal PRScs.10FCVal 0.035 18.641 25.153 1.30e-139 0.032 17.570 11.380 5.23e-30
LDpred2.Inf PRScs.10FCVal 0.030 15.675 22.427 2.15e-111 0.028 15.425 10.597 3.08e-26
DBSLMM.PseudoVal PRScs.10FCVal 0.008 4.357 7.086 1.38e-12 0.008 4.165 3.247 1.17e-03
All.MultiPRS PRScs.10FCVal -0.012 -6.137 -3.972 7.14e-05 -0.014 -7.907 -7.912 2.54e-15
pT+clump.10FCVal PRScs.MultiPRS 0.039 20.316 13.216 7.11e-40 0.034 18.395 9.904 3.99e-23
pT+clump.MultiPRS PRScs.MultiPRS 0.019 9.942 6.477 9.38e-11 0.013 7.108 5.048 4.47e-07
lassosum.10FCVal PRScs.MultiPRS 0.004 2.296 1.501 1.33e-01 0.004 2.360 2.520 1.17e-02
lassosum.MultiPRS PRScs.MultiPRS -0.005 -2.441 -2.364 1.81e-02 -0.007 -3.525 -4.748 2.05e-06
lassosum.PseudoVal PRScs.MultiPRS 0.035 18.232 11.869 1.71e-32 0.030 16.231 10.910 1.03e-27
PRScs.10FCVal PRScs.MultiPRS 0.004 1.960 1.281 2.00e-01 0.004 2.369 4.123 3.75e-05
PRScs.MultiPRS PRScs.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
PRScs.PseudoVal PRScs.MultiPRS 0.006 3.052 1.996 4.59e-02 0.005 2.850 4.988 6.09e-07
SBLUP.Inf PRScs.MultiPRS 0.032 16.361 10.660 1.56e-26 0.031 16.715 11.450 2.36e-30
SBayesR.PseudoVal PRScs.MultiPRS 0.024 12.484 8.155 3.50e-16 0.020 10.899 6.351 2.13e-10
LDpred1.10FCVal PRScs.MultiPRS 0.016 8.158 5.325 1.01e-07 0.016 8.468 8.527 1.50e-17
LDpred1.MultiPRS PRScs.MultiPRS 0.013 6.553 6.298 3.02e-10 0.013 6.748 7.074 1.51e-12
LDpred1.Inf PRScs.MultiPRS 0.031 16.184 10.547 5.26e-26 0.031 16.549 12.276 1.22e-34
LDpred2.10FCVal PRScs.MultiPRS 0.001 0.308 0.202 8.40e-01 0.000 0.050 0.052 9.59e-01
LDpred2.MultiPRS PRScs.MultiPRS -0.003 -1.288 -1.149 2.51e-01 -0.003 -1.705 -1.864 6.23e-02
LDpred2.PseudoVal PRScs.MultiPRS 0.039 20.236 13.167 1.35e-39 0.037 19.523 12.337 5.72e-35
LDpred2.Inf PRScs.MultiPRS 0.034 17.327 11.288 1.50e-29 0.033 17.428 11.333 8.98e-30
DBSLMM.PseudoVal PRScs.MultiPRS 0.012 6.231 4.071 4.68e-05 0.012 6.435 6.210 5.29e-10
All.MultiPRS PRScs.MultiPRS -0.008 -4.057 -3.926 8.65e-05 -0.010 -5.350 -6.565 5.20e-11
pT+clump.10FCVal PRScs.PseudoVal 0.034 17.808 18.786 9.88e-79 0.029 16.001 8.098 5.59e-16
pT+clump.MultiPRS PRScs.PseudoVal 0.013 7.107 4.484 7.33e-06 0.008 4.383 2.758 5.82e-03
lassosum.10FCVal PRScs.PseudoVal -0.001 -0.780 -1.445 1.49e-01 -0.001 -0.504 -0.450 6.53e-01
lassosum.MultiPRS PRScs.PseudoVal -0.011 -5.666 -3.583 3.40e-04 -0.012 -6.561 -6.830 8.51e-12
lassosum.PseudoVal PRScs.PseudoVal 0.029 15.658 20.610 2.25e-94 0.025 13.774 8.784 1.58e-18
PRScs.10FCVal PRScs.PseudoVal -0.002 -1.127 -2.797 5.16e-03 -0.001 -0.495 -0.593 5.54e-01
PRScs.MultiPRS PRScs.PseudoVal -0.006 -3.148 -1.996 4.59e-02 -0.005 -2.933 -4.988 6.09e-07
PRScs.PseudoVal PRScs.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBLUP.Inf PRScs.PseudoVal 0.026 13.728 17.804 6.54e-71 0.026 14.272 8.945 3.73e-19
SBayesR.PseudoVal PRScs.PseudoVal 0.018 9.729 10.739 6.70e-27 0.015 8.285 4.385 1.16e-05
LDpred1.10FCVal PRScs.PseudoVal 0.010 5.267 10.132 3.98e-24 0.011 5.783 5.375 7.67e-08
LDpred1.MultiPRS PRScs.PseudoVal 0.007 3.612 2.287 2.22e-02 0.007 4.013 3.774 1.61e-04
LDpred1.Inf PRScs.PseudoVal 0.026 13.545 19.530 6.08e-85 0.026 14.101 9.822 9.03e-23
LDpred2.10FCVal PRScs.PseudoVal -0.005 -2.830 -5.564 2.64e-08 -0.005 -2.882 -2.731 6.31e-03
LDpred2.MultiPRS PRScs.PseudoVal -0.008 -4.476 -2.833 4.61e-03 -0.009 -4.688 -4.250 2.14e-05
LDpred2.PseudoVal PRScs.PseudoVal 0.033 17.725 22.100 3.14e-108 0.031 17.163 10.328 5.29e-25
LDpred2.Inf PRScs.PseudoVal 0.028 14.725 18.304 7.65e-75 0.027 15.006 9.004 2.18e-19
DBSLMM.PseudoVal PRScs.PseudoVal 0.006 3.279 6.561 5.36e-11 0.007 3.691 3.546 3.92e-04
All.MultiPRS PRScs.PseudoVal -0.014 -7.333 -4.690 2.73e-06 -0.015 -8.440 -8.253 1.55e-16
pT+clump.10FCVal SBLUP.Inf 0.008 4.729 3.517 4.36e-04 0.003 2.017 0.720 4.72e-01
pT+clump.MultiPRS SBLUP.Inf -0.012 -7.675 -4.164 3.13e-05 -0.018 -11.535 -5.236 1.64e-07
lassosum.10FCVal SBLUP.Inf -0.027 -16.817 -18.505 1.88e-76 -0.027 -17.236 -9.096 9.39e-20
lassosum.MultiPRS SBLUP.Inf -0.037 -22.481 -12.218 2.49e-34 -0.038 -24.302 -13.030 8.30e-39
lassosum.PseudoVal SBLUP.Inf 0.004 2.237 1.715 8.63e-02 -0.001 -0.581 -0.214 8.30e-01
PRScs.10FCVal SBLUP.Inf -0.028 -17.219 -22.036 1.30e-107 -0.027 -17.225 -10.594 3.19e-26
PRScs.MultiPRS SBLUP.Inf -0.032 -19.562 -10.660 1.56e-26 -0.031 -20.070 -11.450 2.36e-30
PRScs.PseudoVal SBLUP.Inf -0.026 -15.913 -17.804 6.54e-71 -0.026 -16.648 -8.945 3.73e-19
SBLUP.Inf SBLUP.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBayesR.PseudoVal SBLUP.Inf -0.008 -4.635 -3.881 1.04e-04 -0.011 -6.984 -2.802 5.07e-03
LDpred1.10FCVal SBLUP.Inf -0.016 -9.808 -12.976 1.68e-38 -0.015 -9.902 -6.292 3.13e-10
LDpred1.MultiPRS SBLUP.Inf -0.019 -11.727 -6.385 1.71e-10 -0.019 -11.967 -7.307 2.73e-13
LDpred1.Inf SBLUP.Inf 0.000 -0.212 -0.397 6.91e-01 0.000 -0.199 -0.179 8.58e-01
LDpred2.10FCVal SBLUP.Inf -0.031 -19.193 -19.484 1.50e-84 -0.031 -20.010 -9.751 1.83e-22
LDpred2.MultiPRS SBLUP.Inf -0.034 -21.102 -11.480 1.66e-30 -0.035 -22.117 -11.881 1.48e-32
LDpred2.PseudoVal SBLUP.Inf 0.008 4.632 9.685 3.51e-22 0.005 3.372 3.358 7.86e-04
LDpred2.Inf SBLUP.Inf 0.002 1.155 6.110 9.97e-10 0.001 0.857 2.173 2.98e-02
DBSLMM.PseudoVal SBLUP.Inf -0.020 -12.112 -11.279 1.66e-29 -0.019 -12.343 -5.510 3.59e-08
All.MultiPRS SBLUP.Inf -0.040 -24.413 -13.405 5.68e-41 -0.041 -26.494 -14.031 1.01e-44
pT+clump.10FCVal SBayesR.PseudoVal 0.015 8.949 8.242 1.70e-16 0.014 8.413 3.781 1.56e-04
pT+clump.MultiPRS SBayesR.PseudoVal -0.005 -2.905 -1.650 9.90e-02 -0.007 -4.254 -2.302 2.13e-02
lassosum.10FCVal SBayesR.PseudoVal -0.020 -11.642 -11.949 6.54e-33 -0.016 -9.583 -4.807 1.53e-06
lassosum.MultiPRS SBayesR.PseudoVal -0.029 -17.055 -9.733 2.19e-22 -0.027 -16.187 -9.165 4.94e-20
lassosum.PseudoVal SBayesR.PseudoVal 0.011 6.568 6.858 6.99e-12 0.010 5.985 3.061 2.21e-03
PRScs.10FCVal SBayesR.PseudoVal -0.020 -12.026 -12.128 7.48e-34 -0.016 -9.573 -4.712 2.45e-06
PRScs.MultiPRS SBayesR.PseudoVal -0.024 -14.265 -8.155 3.50e-16 -0.020 -12.232 -6.351 2.13e-10
PRScs.PseudoVal SBayesR.PseudoVal -0.018 -10.778 -10.739 6.70e-27 -0.015 -9.034 -4.385 1.16e-05
SBLUP.Inf SBayesR.PseudoVal 0.008 4.430 3.881 1.04e-04 0.011 6.528 2.802 5.07e-03
SBayesR.PseudoVal SBayesR.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.10FCVal SBayesR.PseudoVal -0.008 -4.943 -5.008 5.51e-07 -0.005 -2.728 -1.353 1.76e-01
LDpred1.MultiPRS SBayesR.PseudoVal -0.012 -6.777 -3.868 1.10e-04 -0.008 -4.658 -2.316 2.06e-02
LDpred1.Inf SBayesR.PseudoVal 0.007 4.227 3.665 2.47e-04 0.011 6.341 2.695 7.04e-03
LDpred2.10FCVal SBayesR.PseudoVal -0.024 -13.913 -14.632 1.76e-48 -0.020 -12.175 -6.250 4.11e-10
LDpred2.MultiPRS SBayesR.PseudoVal -0.027 -15.737 -8.980 2.70e-19 -0.024 -14.145 -7.804 5.98e-15
LDpred2.PseudoVal SBayesR.PseudoVal 0.015 8.857 7.975 1.52e-15 0.016 9.679 4.277 1.90e-05
LDpred2.Inf SBayesR.PseudoVal 0.009 5.534 4.781 1.74e-06 0.012 7.328 3.105 1.91e-03
DBSLMM.PseudoVal SBayesR.PseudoVal -0.012 -7.145 -7.132 9.89e-13 -0.008 -5.009 -2.431 1.50e-02
All.MultiPRS SBayesR.PseudoVal -0.032 -18.901 -10.897 1.19e-27 -0.030 -18.236 -11.200 4.06e-29
pT+clump.10FCVal LDpred1.10FCVal 0.024 13.238 12.312 7.80e-35 0.019 10.845 4.830 1.36e-06
pT+clump.MultiPRS LDpred1.10FCVal 0.003 1.942 1.159 2.46e-01 -0.003 -1.486 -0.860 3.90e-01
lassosum.10FCVal LDpred1.10FCVal -0.011 -6.383 -9.228 2.75e-20 -0.011 -6.673 -4.633 3.61e-06
lassosum.MultiPRS LDpred1.10FCVal -0.021 -11.541 -6.901 5.15e-12 -0.022 -13.102 -10.273 9.28e-25
lassosum.PseudoVal LDpred1.10FCVal 0.020 10.969 12.368 3.90e-35 0.015 8.481 4.616 3.91e-06
PRScs.10FCVal LDpred1.10FCVal -0.012 -6.749 -10.950 6.62e-28 -0.011 -6.663 -5.219 1.80e-07
PRScs.MultiPRS LDpred1.10FCVal -0.016 -8.883 -5.325 1.01e-07 -0.016 -9.251 -8.527 1.50e-17
PRScs.PseudoVal LDpred1.10FCVal -0.010 -5.560 -10.132 3.98e-24 -0.011 -6.138 -5.375 7.67e-08
SBLUP.Inf LDpred1.10FCVal 0.016 8.932 12.976 1.68e-38 0.015 9.010 6.292 3.13e-10
SBayesR.PseudoVal LDpred1.10FCVal 0.008 4.710 5.008 5.51e-07 0.005 2.656 1.353 1.76e-01
LDpred1.10FCVal LDpred1.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.MultiPRS LDpred1.10FCVal -0.003 -1.747 -1.047 2.95e-01 -0.003 -1.879 -4.086 4.39e-05
LDpred1.Inf LDpred1.10FCVal 0.016 8.738 18.234 2.79e-74 0.015 8.829 8.840 9.58e-19
LDpred2.10FCVal LDpred1.10FCVal -0.015 -8.547 -13.324 1.67e-40 -0.016 -9.197 -6.889 5.60e-12
LDpred2.MultiPRS LDpred1.10FCVal -0.018 -10.285 -6.158 7.36e-10 -0.019 -11.114 -8.540 1.34e-17
LDpred2.PseudoVal LDpred1.10FCVal 0.023 13.150 18.108 2.78e-73 0.021 12.078 7.998 1.27e-15
LDpred2.Inf LDpred1.10FCVal 0.018 9.984 13.602 3.90e-42 0.017 9.789 6.405 1.50e-10
DBSLMM.PseudoVal LDpred1.10FCVal -0.004 -2.098 -2.989 2.80e-03 -0.004 -2.221 -1.517 1.29e-01
All.MultiPRS LDpred1.10FCVal -0.024 -13.301 -8.041 8.93e-16 -0.026 -15.096 -11.747 7.30e-32
pT+clump.10FCVal LDpred1.MultiPRS 0.027 14.728 8.939 3.92e-19 0.022 12.490 5.782 7.40e-09
pT+clump.MultiPRS LDpred1.MultiPRS 0.007 3.626 2.201 2.77e-02 0.001 0.386 0.230 8.18e-01
lassosum.10FCVal LDpred1.MultiPRS -0.008 -4.556 -2.782 5.41e-03 -0.008 -4.706 -3.488 4.86e-04
lassosum.MultiPRS LDpred1.MultiPRS -0.017 -9.626 -7.264 3.76e-13 -0.019 -11.016 -9.198 3.64e-20
lassosum.PseudoVal LDpred1.MultiPRS 0.023 12.498 7.599 2.98e-14 0.018 10.169 5.600 2.15e-08
PRScs.10FCVal LDpred1.MultiPRS -0.009 -4.916 -3.002 2.68e-03 -0.008 -4.696 -3.899 9.66e-05
PRScs.MultiPRS LDpred1.MultiPRS -0.013 -7.013 -6.298 3.02e-10 -0.013 -7.236 -7.074 1.51e-12
PRScs.PseudoVal LDpred1.MultiPRS -0.007 -3.747 -2.287 2.22e-02 -0.007 -4.181 -3.774 1.61e-04
SBLUP.Inf LDpred1.MultiPRS 0.019 10.496 6.385 1.71e-10 0.019 10.688 7.307 2.73e-13
SBayesR.PseudoVal LDpred1.MultiPRS 0.012 6.347 3.868 1.10e-04 0.008 4.451 2.316 2.06e-02
LDpred1.10FCVal LDpred1.MultiPRS 0.003 1.717 1.047 2.95e-01 0.003 1.844 4.086 4.39e-05
LDpred1.MultiPRS LDpred1.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.Inf LDpred1.MultiPRS 0.019 10.306 6.270 3.62e-10 0.018 10.510 10.161 2.95e-24
LDpred2.10FCVal LDpred1.MultiPRS -0.012 -6.683 -4.086 4.38e-05 -0.013 -7.183 -5.730 1.00e-08
LDpred2.MultiPRS LDpred1.MultiPRS -0.015 -8.391 -6.405 1.51e-10 -0.016 -9.065 -7.435 1.04e-13
LDpred2.PseudoVal LDpred1.MultiPRS 0.027 14.642 8.895 5.82e-19 0.024 13.699 8.793 1.46e-18
LDpred2.Inf LDpred1.MultiPRS 0.021 11.530 7.012 2.34e-12 0.020 11.453 7.384 1.53e-13
DBSLMM.PseudoVal LDpred1.MultiPRS -0.001 -0.345 -0.210 8.33e-01 -0.001 -0.336 -0.238 8.12e-01
All.MultiPRS LDpred1.MultiPRS -0.021 -11.355 -10.071 7.44e-24 -0.023 -12.974 -10.918 9.41e-28
pT+clump.10FCVal LDpred1.Inf 0.008 4.931 3.784 1.54e-04 0.003 2.212 0.812 4.17e-01
pT+clump.MultiPRS LDpred1.Inf -0.012 -7.447 -4.049 5.13e-05 -0.018 -11.313 -5.153 2.56e-07
lassosum.10FCVal LDpred1.Inf -0.027 -16.569 -18.843 3.35e-79 -0.027 -17.002 -9.266 1.93e-20
lassosum.MultiPRS LDpred1.Inf -0.036 -22.221 -12.100 1.06e-33 -0.038 -24.054 -13.424 4.40e-41
lassosum.PseudoVal LDpred1.Inf 0.004 2.444 1.949 5.13e-02 -0.001 -0.381 -0.146 8.84e-01
PRScs.10FCVal LDpred1.Inf -0.028 -16.970 -22.021 1.81e-107 -0.027 -16.992 -10.615 2.54e-26
PRScs.MultiPRS LDpred1.Inf -0.031 -19.309 -10.547 5.26e-26 -0.031 -19.830 -12.276 1.22e-34
PRScs.PseudoVal LDpred1.Inf -0.026 -15.667 -19.530 6.08e-85 -0.026 -16.416 -9.822 9.03e-23
SBLUP.Inf LDpred1.Inf 0.000 0.212 0.397 6.91e-01 0.000 0.199 0.179 8.58e-01
SBayesR.PseudoVal LDpred1.Inf -0.007 -4.414 -3.665 2.47e-04 -0.011 -6.771 -2.695 7.04e-03
LDpred1.10FCVal LDpred1.Inf -0.016 -9.575 -18.234 2.79e-74 -0.015 -9.683 -8.840 9.58e-19
LDpred1.MultiPRS LDpred1.Inf -0.019 -11.490 -6.270 3.62e-10 -0.018 -11.744 -10.161 2.95e-24
LDpred1.Inf LDpred1.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.10FCVal LDpred1.Inf -0.031 -18.941 -20.398 1.76e-92 -0.031 -19.771 -10.217 1.66e-24
LDpred2.MultiPRS LDpred1.Inf -0.034 -20.845 -11.368 6.03e-30 -0.034 -21.873 -11.953 6.25e-33
LDpred2.PseudoVal LDpred1.Inf 0.008 4.834 7.086 1.38e-12 0.006 3.564 2.502 1.24e-02
LDpred2.Inf LDpred1.Inf 0.002 1.365 2.338 1.94e-02 0.002 1.054 0.866 3.87e-01
DBSLMM.PseudoVal LDpred1.Inf -0.019 -11.874 -12.152 5.57e-34 -0.019 -12.119 -5.940 2.85e-09
All.MultiPRS LDpred1.Inf -0.039 -24.149 -13.283 2.91e-40 -0.041 -26.242 -14.524 8.58e-48
pT+clump.10FCVal LDpred2.10FCVal 0.039 20.070 23.022 2.79e-117 0.034 18.354 10.097 5.71e-24
pT+clump.MultiPRS LDpred2.10FCVal 0.019 9.663 6.274 3.52e-10 0.013 7.061 4.577 4.73e-06
lassosum.10FCVal LDpred2.10FCVal 0.004 1.994 3.526 4.21e-04 0.004 2.311 1.980 4.77e-02
lassosum.MultiPRS LDpred2.10FCVal -0.005 -2.758 -1.797 7.24e-02 -0.007 -3.576 -3.632 2.81e-04
lassosum.PseudoVal LDpred2.10FCVal 0.035 17.979 24.441 6.26e-132 0.030 16.189 10.639 1.96e-26
PRScs.10FCVal LDpred2.10FCVal 0.003 1.657 2.912 3.59e-03 0.004 2.320 1.982 4.75e-02
PRScs.MultiPRS LDpred2.10FCVal -0.001 -0.309 -0.202 8.40e-01 0.000 -0.050 -0.052 9.59e-01
PRScs.PseudoVal LDpred2.10FCVal 0.005 2.752 5.564 2.64e-08 0.005 2.801 2.731 6.31e-03
SBLUP.Inf LDpred2.10FCVal 0.031 16.103 19.484 1.50e-84 0.031 16.673 9.751 1.83e-22
SBayesR.PseudoVal LDpred2.10FCVal 0.024 12.214 14.632 1.76e-48 0.020 10.854 6.250 4.11e-10
LDpred1.10FCVal LDpred2.10FCVal 0.015 7.874 13.324 1.67e-40 0.016 8.422 6.889 5.60e-12
LDpred1.MultiPRS LDpred2.10FCVal 0.012 6.265 4.086 4.38e-05 0.013 6.701 5.730 1.00e-08
LDpred1.Inf LDpred2.10FCVal 0.031 15.925 20.398 1.76e-92 0.031 16.507 10.217 1.66e-24
LDpred2.10FCVal LDpred2.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.MultiPRS LDpred2.10FCVal -0.003 -1.601 -1.044 2.97e-01 -0.003 -1.756 -3.628 2.86e-04
LDpred2.PseudoVal LDpred2.10FCVal 0.039 19.989 23.852 9.63e-126 0.036 19.483 11.222 3.18e-29
LDpred2.Inf LDpred2.10FCVal 0.033 17.072 20.616 1.98e-94 0.033 17.387 10.142 3.60e-24
DBSLMM.PseudoVal LDpred2.10FCVal 0.012 5.941 10.442 1.59e-25 0.012 6.388 5.413 6.21e-08
All.MultiPRS LDpred2.10FCVal -0.008 -4.379 -2.887 3.89e-03 -0.010 -5.403 -6.547 5.88e-11
pT+clump.10FCVal LDpred2.MultiPRS 0.042 21.329 14.034 9.72e-45 0.038 19.763 10.750 5.90e-27
pT+clump.MultiPRS LDpred2.MultiPRS 0.022 11.087 7.324 2.41e-13 0.017 8.665 5.975 2.30e-09
lassosum.10FCVal LDpred2.MultiPRS 0.007 3.538 2.341 1.93e-02 0.008 3.997 3.655 2.57e-04
lassosum.MultiPRS LDpred2.MultiPRS -0.002 -1.139 -1.039 2.99e-01 -0.003 -1.789 -2.019 4.34e-02
lassosum.PseudoVal LDpred2.MultiPRS 0.038 19.272 12.691 6.67e-37 0.034 17.635 11.505 1.24e-30
PRScs.10FCVal LDpred2.MultiPRS 0.006 3.206 2.121 3.39e-02 0.008 4.006 3.855 1.16e-04
PRScs.MultiPRS LDpred2.MultiPRS 0.003 1.271 1.149 2.51e-01 0.003 1.676 1.864 6.23e-02
PRScs.PseudoVal LDpred2.MultiPRS 0.008 4.285 2.833 4.61e-03 0.009 4.478 4.250 2.14e-05
SBLUP.Inf LDpred2.MultiPRS 0.034 17.425 11.480 1.66e-30 0.035 18.111 11.881 1.48e-32
SBayesR.PseudoVal LDpred2.MultiPRS 0.027 13.597 8.980 2.70e-19 0.024 12.392 7.804 5.98e-15
LDpred1.10FCVal LDpred2.MultiPRS 0.018 9.326 6.158 7.36e-10 0.019 10.002 8.540 1.34e-17
LDpred1.MultiPRS LDpred2.MultiPRS 0.015 7.742 6.405 1.51e-10 0.016 8.311 7.435 1.04e-13
LDpred1.Inf LDpred2.MultiPRS 0.034 17.249 11.368 6.03e-30 0.034 17.948 11.953 6.25e-33
LDpred2.10FCVal LDpred2.MultiPRS 0.003 1.576 1.044 2.97e-01 0.003 1.725 3.628 2.86e-04
LDpred2.MultiPRS LDpred2.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.PseudoVal LDpred2.MultiPRS 0.042 21.250 13.985 1.94e-44 0.040 20.872 13.446 3.27e-41
LDpred2.Inf LDpred2.MultiPRS 0.036 18.379 12.106 9.83e-34 0.036 18.812 12.328 6.43e-35
DBSLMM.PseudoVal LDpred2.MultiPRS 0.015 7.423 4.904 9.37e-07 0.015 8.004 6.402 1.54e-10
All.MultiPRS LDpred2.MultiPRS -0.005 -2.734 -2.581 9.85e-03 -0.007 -3.584 -5.795 6.85e-09
pT+clump.10FCVal LDpred2.PseudoVal 0.000 0.101 0.069 9.45e-01 -0.002 -1.402 -0.462 6.44e-01
pT+clump.MultiPRS LDpred2.PseudoVal -0.020 -12.905 -6.666 2.63e-11 -0.023 -15.427 -6.493 8.42e-11
lassosum.10FCVal LDpred2.PseudoVal -0.035 -22.491 -21.630 9.31e-104 -0.032 -21.327 -9.951 2.49e-23
lassosum.MultiPRS LDpred2.PseudoVal -0.044 -28.430 -14.727 4.31e-49 -0.043 -28.639 -13.892 7.06e-44
lassosum.PseudoVal LDpred2.PseudoVal -0.004 -2.512 -1.918 5.52e-02 -0.006 -4.091 -1.520 1.29e-01
PRScs.10FCVal LDpred2.PseudoVal -0.035 -22.913 -25.153 1.30e-139 -0.032 -21.315 -11.380 5.23e-30
PRScs.MultiPRS LDpred2.PseudoVal -0.039 -25.369 -13.167 1.35e-39 -0.037 -24.259 -12.337 5.72e-35
PRScs.PseudoVal LDpred2.PseudoVal -0.033 -21.543 -22.100 3.14e-108 -0.031 -20.718 -10.328 5.29e-25
SBLUP.Inf LDpred2.PseudoVal -0.008 -4.857 -9.685 3.51e-22 -0.005 -3.489 -3.358 7.86e-04
SBayesR.PseudoVal LDpred2.PseudoVal -0.015 -9.718 -7.975 1.52e-15 -0.016 -10.717 -4.277 1.90e-05
LDpred1.10FCVal LDpred2.PseudoVal -0.023 -15.142 -18.108 2.78e-73 -0.021 -13.737 -7.998 1.27e-15
LDpred1.MultiPRS LDpred2.PseudoVal -0.027 -17.153 -8.895 5.82e-19 -0.024 -15.874 -8.793 1.46e-18
LDpred1.Inf LDpred2.PseudoVal -0.008 -5.080 -7.086 1.38e-12 -0.006 -3.696 -2.502 1.24e-02
LDpred2.10FCVal LDpred2.PseudoVal -0.039 -24.983 -23.852 9.63e-126 -0.036 -24.197 -11.222 3.18e-29
LDpred2.MultiPRS LDpred2.PseudoVal -0.042 -26.984 -13.985 1.94e-44 -0.040 -26.378 -13.446 3.27e-41
LDpred2.PseudoVal LDpred2.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.Inf LDpred2.PseudoVal -0.006 -3.646 -8.244 1.67e-16 -0.004 -2.603 -2.831 4.64e-03
DBSLMM.PseudoVal LDpred2.PseudoVal -0.027 -17.558 -15.306 6.92e-53 -0.025 -16.263 -6.881 5.93e-12
All.MultiPRS LDpred2.PseudoVal -0.047 -30.456 -15.914 5.03e-57 -0.047 -30.907 -14.972 1.11e-50
pT+clump.10FCVal LDpred2.Inf 0.006 3.615 2.610 9.04e-03 0.002 1.171 0.407 6.84e-01
pT+clump.MultiPRS LDpred2.Inf -0.014 -8.933 -4.789 1.68e-06 -0.019 -12.499 -5.447 5.13e-08
lassosum.10FCVal LDpred2.Inf -0.029 -18.182 -18.957 3.88e-80 -0.028 -18.249 -9.146 5.91e-20
lassosum.MultiPRS LDpred2.Inf -0.038 -23.912 -12.843 9.36e-38 -0.039 -25.375 -12.884 5.53e-38
lassosum.PseudoVal LDpred2.Inf 0.002 1.094 0.817 4.14e-01 -0.002 -1.450 -0.521 6.02e-01
PRScs.10FCVal LDpred2.Inf -0.030 -18.589 -22.427 2.15e-111 -0.028 -18.238 -10.597 3.08e-26
PRScs.MultiPRS LDpred2.Inf -0.034 -20.959 -11.288 1.50e-29 -0.033 -21.107 -11.333 8.98e-30
PRScs.PseudoVal LDpred2.Inf -0.028 -17.267 -18.304 7.65e-75 -0.027 -17.656 -9.004 2.18e-19
SBLUP.Inf LDpred2.Inf -0.002 -1.169 -6.110 9.97e-10 -0.001 -0.864 -2.173 2.98e-02
SBayesR.PseudoVal LDpred2.Inf -0.009 -5.858 -4.781 1.74e-06 -0.012 -7.908 -3.105 1.91e-03
LDpred1.10FCVal LDpred2.Inf -0.018 -11.091 -13.602 3.90e-42 -0.017 -10.852 -6.405 1.50e-10
LDpred1.MultiPRS LDpred2.Inf -0.021 -13.032 -7.012 2.34e-12 -0.020 -12.934 -7.384 1.53e-13
LDpred1.Inf LDpred2.Inf -0.002 -1.383 -2.338 1.94e-02 -0.002 -1.065 -0.866 3.87e-01
LDpred2.10FCVal LDpred2.Inf -0.033 -20.586 -20.616 1.98e-94 -0.033 -21.046 -10.142 3.60e-24
LDpred2.MultiPRS LDpred2.Inf -0.036 -22.517 -12.106 9.83e-34 -0.036 -23.172 -12.328 6.43e-35
LDpred2.PseudoVal LDpred2.Inf 0.006 3.518 8.244 1.67e-16 0.004 2.537 2.831 4.64e-03
LDpred2.Inf LDpred2.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
DBSLMM.PseudoVal LDpred2.Inf -0.022 -13.422 -11.964 5.48e-33 -0.021 -13.313 -5.706 1.16e-08
All.MultiPRS LDpred2.Inf -0.042 -25.867 -14.038 9.15e-45 -0.043 -27.586 -13.973 2.28e-44
pT+clump.10FCVal DBSLMM.PseudoVal 0.027 15.021 15.912 5.21e-57 0.022 12.782 6.480 9.17e-11
pT+clump.MultiPRS DBSLMM.PseudoVal 0.007 3.957 2.413 1.58e-02 0.001 0.719 0.425 6.71e-01
lassosum.10FCVal DBSLMM.PseudoVal -0.008 -4.197 -5.679 1.35e-08 -0.008 -4.355 -2.823 4.76e-03
lassosum.MultiPRS DBSLMM.PseudoVal -0.017 -9.249 -5.653 1.58e-08 -0.019 -10.645 -8.448 2.96e-17
lassosum.PseudoVal DBSLMM.PseudoVal 0.023 12.798 14.968 1.19e-50 0.018 10.470 5.877 4.17e-09
PRScs.10FCVal DBSLMM.PseudoVal -0.008 -4.555 -7.086 1.38e-12 -0.008 -4.346 -3.247 1.17e-03
PRScs.MultiPRS DBSLMM.PseudoVal -0.012 -6.645 -4.071 4.68e-05 -0.012 -6.878 -6.210 5.29e-10
PRScs.PseudoVal DBSLMM.PseudoVal -0.006 -3.390 -6.561 5.36e-11 -0.007 -3.832 -3.546 3.92e-04
SBLUP.Inf DBSLMM.PseudoVal 0.020 10.803 11.279 1.66e-29 0.019 10.987 5.510 3.59e-08
SBayesR.PseudoVal DBSLMM.PseudoVal 0.012 6.669 7.132 9.89e-13 0.008 4.770 2.431 1.50e-02
LDpred1.10FCVal DBSLMM.PseudoVal 0.004 2.055 2.989 2.80e-03 0.004 2.172 1.517 1.29e-01
LDpred1.MultiPRS DBSLMM.PseudoVal 0.001 0.344 0.210 8.33e-01 0.001 0.334 0.238 8.12e-01
LDpred1.Inf DBSLMM.PseudoVal 0.019 10.614 12.152 5.57e-34 0.019 10.809 5.940 2.85e-09
LDpred2.10FCVal DBSLMM.PseudoVal -0.012 -6.316 -10.442 1.59e-25 -0.012 -6.824 -5.413 6.21e-08
LDpred2.MultiPRS DBSLMM.PseudoVal -0.015 -8.019 -4.904 9.37e-07 -0.015 -8.700 -6.402 1.54e-10
LDpred2.PseudoVal DBSLMM.PseudoVal 0.027 14.935 15.306 6.92e-53 0.025 13.988 6.881 5.93e-12
LDpred2.Inf DBSLMM.PseudoVal 0.022 11.834 11.964 5.48e-33 0.021 11.749 5.706 1.16e-08
DBSLMM.PseudoVal DBSLMM.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
All.MultiPRS DBSLMM.PseudoVal -0.020 -10.972 -6.779 1.21e-11 -0.022 -12.596 -10.100 5.55e-24
pT+clump.10FCVal All.MultiPRS 0.047 23.423 15.977 1.83e-57 0.044 22.539 14.192 1.02e-45
pT+clump.MultiPRS All.MultiPRS 0.027 13.453 9.134 6.58e-20 0.023 11.825 10.002 1.50e-23
lassosum.10FCVal All.MultiPRS 0.012 6.106 4.192 2.76e-05 0.014 7.319 7.869 3.57e-15
lassosum.MultiPRS All.MultiPRS 0.003 1.553 1.392 1.64e-01 0.003 1.733 2.904 3.68e-03
lassosum.PseudoVal All.MultiPRS 0.043 21.420 14.635 1.68e-48 0.040 20.485 14.291 2.50e-46
PRScs.10FCVal All.MultiPRS 0.012 5.782 3.972 7.14e-05 0.014 7.327 7.912 2.54e-15
PRScs.MultiPRS All.MultiPRS 0.008 3.899 3.926 8.65e-05 0.010 5.079 6.565 5.20e-11
PRScs.PseudoVal All.MultiPRS 0.014 6.832 4.690 2.73e-06 0.015 7.783 8.253 1.55e-16
SBLUP.Inf All.MultiPRS 0.040 19.623 13.405 5.68e-41 0.041 20.945 14.031 1.01e-44
SBayesR.PseudoVal All.MultiPRS 0.032 15.897 10.897 1.19e-27 0.030 15.424 11.200 4.06e-29
LDpred1.10FCVal All.MultiPRS 0.024 11.739 8.041 8.93e-16 0.026 13.116 11.747 7.30e-32
LDpred1.MultiPRS All.MultiPRS 0.021 10.197 10.071 7.44e-24 0.023 11.484 10.918 9.41e-28
LDpred1.Inf All.MultiPRS 0.039 19.452 13.283 2.91e-40 0.041 20.787 14.524 8.58e-48
LDpred2.10FCVal All.MultiPRS 0.008 4.195 2.887 3.89e-03 0.010 5.126 6.547 5.88e-11
LDpred2.MultiPRS All.MultiPRS 0.005 2.662 2.581 9.85e-03 0.007 3.460 5.795 6.85e-09
LDpred2.PseudoVal All.MultiPRS 0.047 23.346 15.914 5.03e-57 0.047 23.610 14.972 1.11e-50
LDpred2.Inf All.MultiPRS 0.042 20.551 14.038 9.15e-45 0.043 21.622 13.973 2.28e-44
DBSLMM.PseudoVal All.MultiPRS 0.020 9.887 6.779 1.21e-11 0.022 11.187 10.100 5.55e-24
All.MultiPRS All.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00

Show table: UKBB (UKBB ref)

Average difference between methods in UKBB with UKBB reference
Reference Test CrossVal Diff CrossVal Diff (%) CrossVal Diff Z CrossVal Diff P IndepVal Diff IndepVal Diff (%) IndepVal Diff Z IndepVal Diff P
pT+clump.10FCVal pT+clump.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
pT+clump.10FCVal pT+clump.MultiPRS -0.020 -12.956 -6.725 1.75e-11 -0.022 -14.832 -10.134 3.90e-24
pT+clump.10FCVal lassosum.10FCVal -0.034 -21.879 -19.538 5.27e-85 -0.032 -20.866 -9.057 1.33e-19
pT+clump.10FCVal lassosum.MultiPRS -0.042 -27.196 -14.153 1.80e-45 -0.041 -27.070 -12.564 3.34e-36
pT+clump.10FCVal lassosum.PseudoVal -0.003 -2.238 -1.900 5.74e-02 -0.005 -3.594 -1.484 1.38e-01
pT+clump.10FCVal SBLUP.Inf -0.007 -4.216 -2.965 3.03e-03 -0.004 -2.340 -0.801 4.23e-01
pT+clump.10FCVal SBayesR.PseudoVal -0.025 -16.178 -14.037 9.21e-45 -0.027 -17.640 -7.447 9.55e-14
pT+clump.10FCVal LDpred1.10FCVal -0.021 -13.452 -10.971 5.29e-28 -0.019 -12.510 -4.957 7.16e-07
pT+clump.10FCVal LDpred1.MultiPRS -0.027 -17.087 -8.919 4.70e-19 -0.025 -16.170 -6.671 2.55e-11
pT+clump.10FCVal LDpred1.Inf -0.006 -4.109 -2.989 2.80e-03 -0.003 -2.136 -0.756 4.50e-01
pT+clump.10FCVal LDpred2.10FCVal -0.041 -26.039 -24.945 2.43e-137 -0.039 -25.505 -11.861 1.88e-32
pT+clump.10FCVal LDpred2.MultiPRS -0.043 -27.918 -14.549 5.92e-48 -0.042 -27.643 -12.766 2.54e-37
pT+clump.10FCVal LDpred2.PseudoVal -0.014 -9.284 -8.202 2.36e-16 -0.016 -10.839 -4.632 3.62e-06
pT+clump.10FCVal LDpred2.Inf -0.005 -3.122 -2.159 3.08e-02 -0.003 -1.716 -0.578 5.63e-01
pT+clump.10FCVal DBSLMM.PseudoVal -0.028 -17.895 -16.591 8.16e-62 -0.026 -16.834 -7.580 3.47e-14
pT+clump.10FCVal All.MultiPRS -0.047 -29.944 -15.651 3.29e-55 -0.046 -30.233 -14.824 1.02e-49
pT+clump.MultiPRS pT+clump.10FCVal 0.020 11.470 6.725 1.75e-11 0.022 12.916 10.134 3.90e-24
pT+clump.MultiPRS pT+clump.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
pT+clump.MultiPRS lassosum.10FCVal -0.014 -7.899 -4.655 3.24e-06 -0.009 -5.255 -3.399 6.77e-04
pT+clump.MultiPRS lassosum.MultiPRS -0.022 -12.606 -7.439 1.01e-13 -0.019 -10.657 -7.752 9.08e-15
pT+clump.MultiPRS lassosum.PseudoVal 0.017 9.489 5.563 2.66e-08 0.017 9.786 5.321 1.03e-07
pT+clump.MultiPRS SBLUP.Inf 0.014 7.737 4.543 5.55e-06 0.019 10.879 5.522 3.36e-08
pT+clump.MultiPRS SBayesR.PseudoVal -0.005 -2.852 -1.676 9.38e-02 -0.004 -2.445 -1.536 1.25e-01
pT+clump.MultiPRS LDpred1.10FCVal -0.001 -0.439 -0.258 7.96e-01 0.004 2.022 1.182 2.37e-01
pT+clump.MultiPRS LDpred1.MultiPRS -0.006 -3.657 -2.153 3.13e-02 -0.002 -1.165 -0.708 4.79e-01
pT+clump.MultiPRS LDpred1.Inf 0.014 7.833 4.599 4.24e-06 0.019 11.056 5.612 2.00e-08
pT+clump.MultiPRS LDpred2.10FCVal -0.020 -11.582 -6.828 8.63e-12 -0.016 -9.295 -6.073 1.26e-09
pT+clump.MultiPRS LDpred2.MultiPRS -0.023 -13.246 -7.814 5.53e-15 -0.019 -11.156 -7.578 3.52e-14
pT+clump.MultiPRS LDpred2.PseudoVal 0.006 3.251 1.908 5.64e-02 0.006 3.477 1.905 5.68e-02
pT+clump.MultiPRS LDpred2.Inf 0.015 8.706 5.110 3.23e-07 0.020 11.422 5.644 1.66e-08
pT+clump.MultiPRS DBSLMM.PseudoVal -0.008 -4.372 -2.573 1.01e-02 -0.003 -1.743 -1.053 2.92e-01
pT+clump.MultiPRS All.MultiPRS -0.026 -15.040 -8.879 6.75e-19 -0.023 -13.412 -10.185 2.33e-24
lassosum.10FCVal pT+clump.10FCVal 0.034 17.951 19.538 5.27e-85 0.032 17.264 9.057 1.33e-19
lassosum.10FCVal pT+clump.MultiPRS 0.014 7.321 4.655 3.24e-06 0.009 4.993 3.399 6.77e-04
lassosum.10FCVal lassosum.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.10FCVal lassosum.MultiPRS -0.008 -4.363 -2.779 5.45e-03 -0.009 -5.132 -7.183 6.83e-13
lassosum.10FCVal lassosum.PseudoVal 0.031 16.115 20.975 1.11e-97 0.026 14.290 9.002 2.22e-19
lassosum.10FCVal SBLUP.Inf 0.027 14.492 18.554 7.57e-77 0.028 15.328 9.456 3.19e-21
lassosum.10FCVal SBayesR.PseudoVal 0.009 4.678 6.222 4.91e-10 0.005 2.670 1.706 8.80e-02
lassosum.10FCVal LDpred1.10FCVal 0.013 6.914 10.722 8.03e-27 0.013 6.914 5.172 2.32e-07
lassosum.10FCVal LDpred1.MultiPRS 0.007 3.932 2.517 1.18e-02 0.007 3.886 3.058 2.22e-03
lassosum.10FCVal LDpred1.Inf 0.028 14.580 19.256 1.27e-82 0.028 15.496 9.850 6.83e-23
lassosum.10FCVal LDpred2.10FCVal -0.006 -3.413 -6.343 2.25e-10 -0.007 -3.838 -3.466 5.28e-04
lassosum.10FCVal LDpred2.MultiPRS -0.009 -4.955 -3.161 1.57e-03 -0.010 -5.607 -5.133 2.86e-07
lassosum.10FCVal LDpred2.PseudoVal 0.020 10.334 14.051 7.57e-45 0.015 8.296 5.456 4.86e-08
lassosum.10FCVal LDpred2.Inf 0.029 15.390 19.026 1.04e-80 0.029 15.845 9.437 3.83e-21
lassosum.10FCVal DBSLMM.PseudoVal 0.006 3.269 4.710 2.48e-06 0.006 3.336 2.316 2.05e-02
lassosum.10FCVal All.MultiPRS -0.013 -6.618 -4.238 2.26e-05 -0.014 -7.750 -7.769 7.93e-15
lassosum.MultiPRS pT+clump.10FCVal 0.042 21.381 14.153 1.80e-45 0.041 21.303 12.564 3.34e-36
lassosum.MultiPRS pT+clump.MultiPRS 0.022 11.195 7.439 1.01e-13 0.019 9.631 7.752 9.08e-15
lassosum.MultiPRS lassosum.10FCVal 0.008 4.180 2.779 5.45e-03 0.009 4.882 7.183 6.83e-13
lassosum.MultiPRS lassosum.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.MultiPRS lassosum.PseudoVal 0.039 19.622 13.005 1.15e-38 0.036 18.474 13.953 3.02e-44
lassosum.MultiPRS SBLUP.Inf 0.036 18.066 11.967 5.30e-33 0.038 19.462 12.949 2.39e-38
lassosum.MultiPRS SBayesR.PseudoVal 0.017 8.663 5.756 8.60e-09 0.014 7.421 5.651 1.60e-08
lassosum.MultiPRS LDpred1.10FCVal 0.021 10.805 7.169 7.54e-13 0.022 11.458 10.252 1.16e-24
lassosum.MultiPRS LDpred1.MultiPRS 0.016 7.947 7.480 7.43e-14 0.017 8.578 8.221 2.02e-16
lassosum.MultiPRS LDpred1.Inf 0.036 18.151 12.022 2.71e-33 0.038 19.622 13.682 1.29e-42
lassosum.MultiPRS LDpred2.10FCVal 0.002 0.910 0.606 5.45e-01 0.002 1.231 1.391 1.64e-01
lassosum.MultiPRS LDpred2.MultiPRS -0.001 -0.568 -0.526 5.99e-01 -0.001 -0.451 -0.550 5.82e-01
lassosum.MultiPRS LDpred2.PseudoVal 0.028 14.082 9.345 9.22e-21 0.025 12.773 9.486 2.40e-21
lassosum.MultiPRS LDpred2.Inf 0.037 18.927 12.534 4.86e-36 0.038 19.953 12.703 5.70e-37
lassosum.MultiPRS DBSLMM.PseudoVal 0.014 7.312 4.858 1.19e-06 0.016 8.055 7.186 6.66e-13
lassosum.MultiPRS All.MultiPRS -0.004 -2.161 -2.255 2.42e-02 -0.005 -2.489 -4.060 4.90e-05
lassosum.PseudoVal pT+clump.10FCVal 0.003 2.189 1.900 5.74e-02 0.005 3.470 1.484 1.38e-01
lassosum.PseudoVal pT+clump.MultiPRS -0.017 -10.484 -5.563 2.66e-08 -0.017 -10.848 -5.321 1.03e-07
lassosum.PseudoVal lassosum.10FCVal -0.031 -19.211 -20.975 1.11e-97 -0.026 -16.673 -9.002 2.22e-19
lassosum.PseudoVal lassosum.MultiPRS -0.039 -24.412 -13.005 1.15e-38 -0.036 -22.661 -13.953 3.02e-44
lassosum.PseudoVal lassosum.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.PseudoVal SBLUP.Inf -0.003 -1.935 -1.461 1.44e-01 0.002 1.211 0.452 6.51e-01
lassosum.PseudoVal SBayesR.PseudoVal -0.022 -13.634 -13.869 9.73e-44 -0.021 -13.558 -6.825 8.82e-12
lassosum.PseudoVal LDpred1.10FCVal -0.017 -10.969 -10.752 5.78e-27 -0.014 -8.606 -4.178 2.94e-05
lassosum.PseudoVal LDpred1.MultiPRS -0.023 -14.524 -7.759 8.56e-15 -0.019 -12.139 -6.167 6.97e-10
lassosum.PseudoVal LDpred1.Inf -0.003 -1.830 -1.437 1.51e-01 0.002 1.407 0.547 5.84e-01
lassosum.PseudoVal LDpred2.10FCVal -0.037 -23.280 -26.410 1.05e-153 -0.033 -21.151 -11.864 1.83e-32
lassosum.PseudoVal LDpred2.MultiPRS -0.040 -25.118 -13.393 6.63e-41 -0.036 -23.214 -12.904 4.26e-38
lassosum.PseudoVal LDpred2.PseudoVal -0.011 -6.892 -6.800 1.05e-11 -0.011 -6.993 -3.415 6.37e-04
lassosum.PseudoVal LDpred2.Inf -0.001 -0.865 -0.642 5.21e-01 0.003 1.813 0.665 5.06e-01
lassosum.PseudoVal DBSLMM.PseudoVal -0.024 -15.314 -15.924 4.32e-57 -0.020 -12.780 -6.561 5.35e-11
lassosum.PseudoVal All.MultiPRS -0.043 -27.100 -14.502 1.18e-47 -0.040 -25.714 -14.423 3.71e-47
SBLUP.Inf pT+clump.10FCVal 0.007 4.046 2.965 3.03e-03 0.004 2.286 0.801 4.23e-01
SBLUP.Inf pT+clump.MultiPRS -0.014 -8.386 -4.543 5.55e-06 -0.019 -12.207 -5.522 3.36e-08
SBLUP.Inf lassosum.10FCVal -0.027 -16.948 -18.554 7.57e-77 -0.028 -18.103 -9.456 3.19e-21
SBLUP.Inf lassosum.MultiPRS -0.036 -22.050 -11.967 5.30e-33 -0.038 -24.165 -12.949 2.39e-38
SBLUP.Inf lassosum.PseudoVal 0.003 1.898 1.461 1.44e-01 -0.002 -1.226 -0.452 6.51e-01
SBLUP.Inf SBLUP.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBLUP.Inf SBayesR.PseudoVal -0.019 -11.477 -12.012 3.06e-33 -0.023 -14.951 -7.473 7.83e-14
SBLUP.Inf LDpred1.10FCVal -0.014 -8.862 -11.626 3.05e-31 -0.015 -9.938 -6.223 4.89e-10
SBLUP.Inf LDpred1.MultiPRS -0.020 -12.350 -6.734 1.65e-11 -0.021 -13.514 -8.056 7.91e-16
SBLUP.Inf LDpred1.Inf 0.000 0.103 0.196 8.45e-01 0.000 0.198 0.179 8.58e-01
SBLUP.Inf LDpred2.10FCVal -0.034 -20.940 -22.638 1.82e-113 -0.035 -22.636 -11.689 1.45e-31
SBLUP.Inf LDpred2.MultiPRS -0.037 -22.743 -12.352 4.74e-35 -0.038 -24.725 -12.961 2.03e-38
SBLUP.Inf LDpred2.PseudoVal -0.008 -4.863 -4.109 3.97e-05 -0.013 -8.305 -3.357 7.88e-04
SBLUP.Inf LDpred2.Inf 0.002 1.050 6.837 8.06e-12 0.001 0.610 1.898 5.77e-02
SBLUP.Inf DBSLMM.PseudoVal -0.021 -13.125 -12.177 4.12e-34 -0.022 -14.163 -6.265 3.72e-10
SBLUP.Inf All.MultiPRS -0.040 -24.687 -13.461 2.65e-41 -0.042 -27.256 -14.302 2.12e-46
SBayesR.PseudoVal pT+clump.10FCVal 0.025 13.925 14.037 9.21e-45 0.027 14.995 7.447 9.55e-14
SBayesR.PseudoVal pT+clump.MultiPRS 0.005 2.773 1.676 9.38e-02 0.004 2.387 1.536 1.25e-01
SBayesR.PseudoVal lassosum.10FCVal -0.009 -4.908 -6.222 4.91e-10 -0.005 -2.743 -1.706 8.80e-02
SBayesR.PseudoVal lassosum.MultiPRS -0.017 -9.484 -5.756 8.60e-09 -0.014 -8.016 -5.651 1.60e-08
SBayesR.PseudoVal lassosum.PseudoVal 0.022 11.998 13.869 9.73e-44 0.021 11.939 6.825 8.82e-12
SBayesR.PseudoVal SBLUP.Inf 0.019 10.296 12.012 3.06e-33 0.023 13.006 7.473 7.83e-14
SBayesR.PseudoVal SBayesR.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBayesR.PseudoVal LDpred1.10FCVal 0.004 2.346 3.065 2.17e-03 0.008 4.361 2.801 5.09e-03
SBayesR.PseudoVal LDpred1.MultiPRS -0.001 -0.783 -0.477 6.33e-01 0.002 1.249 0.843 3.99e-01
SBayesR.PseudoVal LDpred1.Inf 0.019 10.388 11.672 1.78e-31 0.024 13.179 7.298 2.93e-13
SBayesR.PseudoVal LDpred2.10FCVal -0.015 -8.488 -11.790 4.41e-32 -0.012 -6.686 -4.556 5.21e-06
SBayesR.PseudoVal LDpred2.MultiPRS -0.018 -10.106 -6.141 8.22e-10 -0.015 -8.503 -6.224 4.85e-10
SBayesR.PseudoVal LDpred2.PseudoVal 0.011 5.933 7.668 1.75e-14 0.010 5.781 3.674 2.39e-04
SBayesR.PseudoVal LDpred2.Inf 0.020 11.237 12.864 7.18e-38 0.024 13.536 7.631 2.33e-14
SBayesR.PseudoVal DBSLMM.PseudoVal -0.003 -1.478 -1.714 8.65e-02 0.001 0.685 0.389 6.97e-01
SBayesR.PseudoVal All.MultiPRS -0.021 -11.850 -7.228 4.90e-13 -0.019 -10.705 -8.325 8.40e-17
LDpred1.10FCVal pT+clump.10FCVal 0.021 11.857 10.971 5.29e-28 0.019 11.119 4.957 7.16e-07
LDpred1.10FCVal pT+clump.MultiPRS 0.001 0.437 0.258 7.96e-01 -0.004 -2.064 -1.182 2.37e-01
LDpred1.10FCVal lassosum.10FCVal -0.013 -7.428 -10.722 8.03e-27 -0.013 -7.427 -5.172 2.32e-07
LDpred1.10FCVal lassosum.MultiPRS -0.021 -12.114 -7.169 7.54e-13 -0.022 -12.941 -10.252 1.16e-24
LDpred1.10FCVal lassosum.PseudoVal 0.017 9.885 10.752 5.78e-27 0.014 7.924 4.178 2.94e-05
LDpred1.10FCVal SBLUP.Inf 0.014 8.141 11.626 3.05e-31 0.015 9.040 6.223 4.89e-10
LDpred1.10FCVal SBayesR.PseudoVal -0.004 -2.402 -3.065 2.17e-03 -0.008 -4.559 -2.801 5.09e-03
LDpred1.10FCVal LDpred1.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.10FCVal LDpred1.MultiPRS -0.006 -3.204 -1.906 5.67e-02 -0.006 -3.253 -5.635 1.75e-08
LDpred1.10FCVal LDpred1.Inf 0.015 8.236 16.927 2.84e-64 0.016 9.220 9.127 7.05e-20
LDpred1.10FCVal LDpred2.10FCVal -0.020 -11.094 -18.082 4.46e-73 -0.020 -11.550 -9.115 7.89e-20
LDpred1.10FCVal LDpred2.MultiPRS -0.023 -12.751 -7.556 4.15e-14 -0.023 -13.450 -10.224 1.55e-24
LDpred1.10FCVal LDpred2.PseudoVal 0.006 3.674 4.265 2.00e-05 0.003 1.485 0.834 4.04e-01
LDpred1.10FCVal LDpred2.Inf 0.016 9.105 12.397 2.71e-35 0.016 9.594 6.299 3.00e-10
LDpred1.10FCVal DBSLMM.PseudoVal -0.007 -3.916 -5.736 9.70e-09 -0.007 -3.843 -2.708 6.76e-03
LDpred1.10FCVal All.MultiPRS -0.026 -14.537 -8.647 5.29e-18 -0.027 -15.752 -11.997 3.69e-33
LDpred1.MultiPRS pT+clump.10FCVal 0.027 14.593 8.919 4.70e-19 0.025 13.919 6.671 2.55e-11
LDpred1.MultiPRS pT+clump.MultiPRS 0.006 3.528 2.153 3.13e-02 0.002 1.152 0.708 4.79e-01
LDpred1.MultiPRS lassosum.10FCVal -0.007 -4.093 -2.517 1.18e-02 -0.007 -4.043 -3.058 2.22e-03
LDpred1.MultiPRS lassosum.MultiPRS -0.016 -8.634 -7.480 7.43e-14 -0.017 -9.383 -8.221 2.02e-16
LDpred1.MultiPRS lassosum.PseudoVal 0.023 12.682 7.759 8.56e-15 0.019 10.825 6.167 6.97e-10
LDpred1.MultiPRS SBLUP.Inf 0.020 10.992 6.734 1.65e-11 0.021 11.905 8.056 7.91e-16
LDpred1.MultiPRS SBayesR.PseudoVal 0.001 0.777 0.477 6.33e-01 -0.002 -1.265 -0.843 3.99e-01
LDpred1.MultiPRS LDpred1.10FCVal 0.006 3.104 1.906 5.67e-02 0.006 3.151 5.635 1.75e-08
LDpred1.MultiPRS LDpred1.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.MultiPRS LDpred1.Inf 0.020 11.084 6.789 1.13e-11 0.021 12.080 11.268 1.89e-29
LDpred1.MultiPRS LDpred2.10FCVal -0.014 -7.646 -4.709 2.49e-06 -0.014 -8.036 -7.068 1.57e-12
LDpred1.MultiPRS LDpred2.MultiPRS -0.017 -9.251 -7.125 1.04e-12 -0.017 -9.876 -8.372 5.66e-17
LDpred1.MultiPRS LDpred2.PseudoVal 0.012 6.664 4.088 4.35e-05 0.008 4.589 2.785 5.35e-03
LDpred1.MultiPRS LDpred2.Inf 0.022 11.927 7.305 2.78e-13 0.022 12.442 8.018 1.07e-15
LDpred1.MultiPRS DBSLMM.PseudoVal -0.001 -0.690 -0.424 6.72e-01 -0.001 -0.572 -0.420 6.74e-01
LDpred1.MultiPRS All.MultiPRS -0.020 -10.981 -8.540 1.34e-17 -0.021 -12.105 -10.450 1.46e-25
LDpred1.Inf pT+clump.10FCVal 0.006 3.947 2.989 2.80e-03 0.003 2.092 0.756 4.50e-01
LDpred1.Inf pT+clump.MultiPRS -0.014 -8.498 -4.599 4.24e-06 -0.019 -12.430 -5.612 2.00e-08
LDpred1.Inf lassosum.10FCVal -0.028 -17.069 -19.256 1.27e-82 -0.028 -18.338 -9.850 6.83e-23
LDpred1.Inf lassosum.MultiPRS -0.036 -22.176 -12.022 2.71e-33 -0.038 -24.412 -13.682 1.29e-42
LDpred1.Inf lassosum.PseudoVal 0.003 1.797 1.437 1.51e-01 -0.002 -1.427 -0.547 5.84e-01
LDpred1.Inf SBLUP.Inf 0.000 -0.103 -0.196 8.45e-01 0.000 -0.199 -0.179 8.58e-01
LDpred1.Inf SBayesR.PseudoVal -0.019 -11.592 -11.672 1.78e-31 -0.024 -15.179 -7.298 2.93e-13
LDpred1.Inf LDpred1.10FCVal -0.015 -8.975 -16.927 2.84e-64 -0.016 -10.157 -9.127 7.05e-20
LDpred1.Inf LDpred1.MultiPRS -0.020 -12.466 -6.789 1.13e-11 -0.021 -13.740 -11.268 1.89e-29
LDpred1.Inf LDpred1.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.Inf LDpred2.10FCVal -0.034 -21.065 -23.701 3.52e-124 -0.035 -22.880 -12.284 1.11e-34
LDpred1.Inf LDpred2.MultiPRS -0.037 -22.870 -12.410 2.32e-35 -0.039 -24.973 -13.301 2.28e-40
LDpred1.Inf LDpred2.PseudoVal -0.008 -4.971 -4.384 1.16e-05 -0.013 -8.521 -3.591 3.29e-04
LDpred1.Inf LDpred2.Inf 0.002 0.948 1.653 9.83e-02 0.001 0.412 0.342 7.32e-01
LDpred1.Inf DBSLMM.PseudoVal -0.021 -13.242 -13.584 4.96e-42 -0.022 -14.390 -7.034 2.01e-12
LDpred1.Inf All.MultiPRS -0.040 -24.816 -13.511 1.34e-41 -0.043 -27.509 -14.911 2.82e-50
LDpred2.10FCVal pT+clump.10FCVal 0.041 20.660 24.945 2.43e-137 0.039 20.322 11.861 1.88e-32
LDpred2.10FCVal pT+clump.MultiPRS 0.020 10.380 6.828 8.63e-12 0.016 8.504 6.073 1.26e-09
LDpred2.10FCVal lassosum.10FCVal 0.006 3.301 6.343 2.25e-10 0.007 3.696 3.466 5.28e-04
LDpred2.10FCVal lassosum.MultiPRS -0.002 -0.918 -0.606 5.45e-01 -0.002 -1.247 -1.391 1.64e-01
LDpred2.10FCVal lassosum.PseudoVal 0.037 18.884 26.410 1.05e-153 0.033 17.458 11.864 1.83e-32
LDpred2.10FCVal SBLUP.Inf 0.034 17.314 22.638 1.82e-113 0.035 18.458 11.689 1.45e-31
LDpred2.10FCVal SBayesR.PseudoVal 0.015 7.824 11.790 4.41e-32 0.012 6.267 4.556 5.21e-06
LDpred2.10FCVal LDpred1.10FCVal 0.020 9.986 18.082 4.46e-73 0.020 10.354 9.115 7.89e-20
LDpred2.10FCVal LDpred1.MultiPRS 0.014 7.103 4.709 2.49e-06 0.014 7.438 7.068 1.57e-12
LDpred2.10FCVal LDpred1.Inf 0.034 17.400 23.701 3.52e-124 0.035 18.620 12.284 1.11e-34
LDpred2.10FCVal LDpred2.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.10FCVal LDpred2.MultiPRS -0.003 -1.491 -0.985 3.25e-01 -0.003 -1.703 -3.887 1.02e-04
LDpred2.10FCVal LDpred2.PseudoVal 0.026 13.293 25.675 2.21e-145 0.022 11.686 10.937 7.68e-28
LDpred2.10FCVal LDpred2.Inf 0.036 18.182 23.582 5.94e-123 0.036 18.955 11.900 1.19e-32
LDpred2.10FCVal DBSLMM.PseudoVal 0.013 6.462 11.787 4.56e-32 0.013 6.909 6.090 1.13e-09
LDpred2.10FCVal All.MultiPRS -0.006 -3.099 -2.056 3.98e-02 -0.007 -3.767 -5.191 2.09e-07
LDpred2.MultiPRS pT+clump.10FCVal 0.043 21.825 14.549 5.92e-48 0.042 21.656 12.766 2.54e-37
LDpred2.MultiPRS pT+clump.MultiPRS 0.023 11.697 7.814 5.53e-15 0.019 10.037 7.578 3.52e-14
LDpred2.MultiPRS lassosum.10FCVal 0.009 4.721 3.161 1.57e-03 0.010 5.309 5.133 2.86e-07
LDpred2.MultiPRS lassosum.MultiPRS 0.001 0.565 0.526 5.99e-01 0.001 0.449 0.550 5.82e-01
LDpred2.MultiPRS lassosum.PseudoVal 0.040 20.076 13.393 6.63e-41 0.036 18.841 12.904 4.26e-38
LDpred2.MultiPRS SBLUP.Inf 0.037 18.529 12.352 4.74e-35 0.038 19.824 12.961 2.03e-38
LDpred2.MultiPRS SBayesR.PseudoVal 0.018 9.178 6.141 8.22e-10 0.015 7.837 6.224 4.85e-10
LDpred2.MultiPRS LDpred1.10FCVal 0.023 11.309 7.556 4.15e-14 0.023 11.856 10.224 1.55e-24
LDpred2.MultiPRS LDpred1.MultiPRS 0.017 8.467 7.125 1.04e-12 0.017 8.988 8.372 5.66e-17
LDpred2.MultiPRS LDpred1.Inf 0.037 18.613 12.410 2.32e-35 0.039 19.983 13.301 2.28e-40
LDpred2.MultiPRS LDpred2.10FCVal 0.003 1.469 0.985 3.25e-01 0.003 1.675 3.887 1.02e-04
LDpred2.MultiPRS LDpred2.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.MultiPRS LDpred2.PseudoVal 0.029 14.567 9.733 2.19e-22 0.025 13.165 12.270 1.32e-34
LDpred2.MultiPRS LDpred2.Inf 0.039 19.385 12.919 3.50e-38 0.039 20.312 13.172 1.27e-39
LDpred2.MultiPRS DBSLMM.PseudoVal 0.016 7.836 5.239 1.61e-07 0.016 8.468 7.201 6.00e-13
LDpred2.MultiPRS All.MultiPRS -0.003 -1.584 -1.847 6.47e-02 -0.004 -2.029 -3.895 9.83e-05
LDpred2.PseudoVal pT+clump.10FCVal 0.014 8.496 8.202 2.36e-16 0.016 9.779 4.632 3.62e-06
LDpred2.PseudoVal pT+clump.MultiPRS -0.006 -3.360 -1.908 5.64e-02 -0.006 -3.602 -1.905 5.68e-02
LDpred2.PseudoVal lassosum.10FCVal -0.020 -11.525 -14.051 7.57e-45 -0.015 -9.047 -5.456 4.86e-08
LDpred2.PseudoVal lassosum.MultiPRS -0.028 -16.390 -9.345 9.22e-21 -0.025 -14.644 -9.486 2.40e-21
LDpred2.PseudoVal lassosum.PseudoVal 0.011 6.448 6.800 1.05e-11 0.011 6.536 3.415 6.37e-04
LDpred2.PseudoVal SBLUP.Inf 0.008 4.637 4.109 3.97e-05 0.013 7.668 3.357 7.88e-04
LDpred2.PseudoVal SBayesR.PseudoVal -0.011 -6.307 -7.668 1.75e-14 -0.010 -6.136 -3.674 2.39e-04
LDpred2.PseudoVal LDpred1.10FCVal -0.006 -3.814 -4.265 2.00e-05 -0.003 -1.508 -0.834 4.04e-01
LDpred2.PseudoVal LDpred1.MultiPRS -0.012 -7.140 -4.088 4.35e-05 -0.008 -4.810 -2.785 5.35e-03
LDpred2.PseudoVal LDpred1.Inf 0.008 4.736 4.384 1.16e-05 0.013 7.852 3.591 3.29e-04
LDpred2.PseudoVal LDpred2.10FCVal -0.026 -15.331 -25.675 2.21e-145 -0.022 -13.232 -10.937 7.68e-28
LDpred2.PseudoVal LDpred2.MultiPRS -0.029 -17.051 -9.733 2.19e-22 -0.025 -15.161 -12.270 1.32e-34
LDpred2.PseudoVal LDpred2.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.PseudoVal LDpred2.Inf 0.010 5.639 4.981 6.33e-07 0.014 8.231 3.590 3.31e-04
LDpred2.PseudoVal DBSLMM.PseudoVal -0.013 -7.879 -9.195 3.74e-20 -0.009 -5.409 -3.114 1.84e-03
LDpred2.PseudoVal All.MultiPRS -0.032 -18.905 -10.803 3.34e-27 -0.029 -17.497 -12.906 4.15e-38
LDpred2.Inf pT+clump.10FCVal 0.005 3.028 2.159 3.08e-02 0.003 1.687 0.578 5.63e-01
LDpred2.Inf pT+clump.MultiPRS -0.015 -9.536 -5.110 3.23e-07 -0.020 -12.895 -5.644 1.66e-08
LDpred2.Inf lassosum.10FCVal -0.029 -18.189 -19.026 1.04e-80 -0.029 -18.828 -9.437 3.83e-21
LDpred2.Inf lassosum.MultiPRS -0.037 -23.345 -12.534 4.86e-36 -0.038 -24.926 -12.703 5.70e-37
LDpred2.Inf lassosum.PseudoVal 0.001 0.857 0.642 5.21e-01 -0.003 -1.847 -0.665 5.06e-01
LDpred2.Inf SBLUP.Inf -0.002 -1.061 -6.837 8.06e-12 -0.001 -0.613 -1.898 5.77e-02
LDpred2.Inf SBayesR.PseudoVal -0.020 -12.660 -12.864 7.18e-38 -0.024 -15.656 -7.631 2.33e-14
LDpred2.Inf LDpred1.10FCVal -0.016 -10.017 -12.397 2.71e-35 -0.016 -10.612 -6.299 3.00e-10
LDpred2.Inf LDpred1.MultiPRS -0.022 -13.542 -7.305 2.78e-13 -0.022 -14.211 -8.018 1.07e-15
LDpred2.Inf LDpred1.Inf -0.002 -0.957 -1.653 9.83e-02 -0.001 -0.414 -0.342 7.32e-01
LDpred2.Inf LDpred2.10FCVal -0.036 -22.223 -23.582 5.94e-123 -0.036 -23.388 -11.900 1.19e-32
LDpred2.Inf LDpred2.MultiPRS -0.039 -24.046 -12.919 3.50e-38 -0.039 -25.490 -13.172 1.27e-39
LDpred2.Inf LDpred2.PseudoVal -0.010 -5.976 -4.981 6.33e-07 -0.014 -8.969 -3.590 3.31e-04
LDpred2.Inf LDpred2.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.Inf DBSLMM.PseudoVal -0.023 -14.325 -12.770 2.41e-37 -0.023 -14.863 -6.344 2.24e-10
LDpred2.Inf All.MultiPRS -0.042 -26.010 -14.031 1.01e-44 -0.043 -28.036 -14.145 1.99e-45
DBSLMM.PseudoVal pT+clump.10FCVal 0.028 15.179 16.591 8.16e-62 0.026 14.409 7.580 3.47e-14
DBSLMM.PseudoVal pT+clump.MultiPRS 0.008 4.189 2.573 1.01e-02 0.003 1.714 1.053 2.92e-01
DBSLMM.PseudoVal lassosum.10FCVal -0.006 -3.379 -4.710 2.48e-06 -0.006 -3.451 -2.316 2.05e-02
DBSLMM.PseudoVal lassosum.MultiPRS -0.014 -7.889 -4.858 1.19e-06 -0.016 -8.761 -7.186 6.66e-13
DBSLMM.PseudoVal lassosum.PseudoVal 0.024 13.280 15.924 4.32e-57 0.020 11.332 6.561 5.35e-11
DBSLMM.PseudoVal SBLUP.Inf 0.021 11.602 12.177 4.12e-34 0.022 12.406 6.265 3.72e-10
DBSLMM.PseudoVal SBayesR.PseudoVal 0.003 1.457 1.714 8.65e-02 -0.001 -0.690 -0.389 6.97e-01
DBSLMM.PseudoVal LDpred1.10FCVal 0.007 3.768 5.736 9.70e-09 0.007 3.701 2.708 6.76e-03
DBSLMM.PseudoVal LDpred1.MultiPRS 0.001 0.685 0.424 6.72e-01 0.001 0.568 0.420 6.74e-01
DBSLMM.PseudoVal LDpred1.Inf 0.021 11.694 13.584 4.96e-42 0.022 12.580 7.034 2.01e-12
DBSLMM.PseudoVal LDpred2.10FCVal -0.013 -6.908 -11.787 4.56e-32 -0.013 -7.422 -6.090 1.13e-09
DBSLMM.PseudoVal LDpred2.MultiPRS -0.016 -8.502 -5.239 1.61e-07 -0.016 -9.251 -7.201 6.00e-13
DBSLMM.PseudoVal LDpred2.PseudoVal 0.013 7.303 9.195 3.74e-20 0.009 5.131 3.114 1.84e-03
DBSLMM.PseudoVal LDpred2.Inf 0.023 12.530 12.770 2.41e-37 0.023 12.940 6.344 2.24e-10
DBSLMM.PseudoVal DBSLMM.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
DBSLMM.PseudoVal All.MultiPRS -0.019 -10.221 -6.325 2.53e-10 -0.020 -11.468 -9.376 6.83e-21
All.MultiPRS pT+clump.10FCVal 0.047 23.044 15.651 3.29e-55 0.046 23.215 14.824 1.02e-49
All.MultiPRS pT+clump.MultiPRS 0.026 13.073 8.879 6.75e-19 0.023 11.826 10.185 2.33e-24
All.MultiPRS lassosum.10FCVal 0.013 6.207 4.238 2.26e-05 0.014 7.192 7.769 7.93e-15
All.MultiPRS lassosum.MultiPRS 0.004 2.115 2.255 2.42e-02 0.005 2.429 4.060 4.90e-05
All.MultiPRS lassosum.PseudoVal 0.043 21.322 14.502 1.18e-47 0.040 20.455 14.423 3.71e-47
All.MultiPRS SBLUP.Inf 0.040 19.799 13.461 2.65e-41 0.042 21.418 14.302 2.12e-46
All.MultiPRS SBayesR.PseudoVal 0.021 10.594 7.228 4.90e-13 0.019 9.670 8.325 8.40e-17
All.MultiPRS LDpred1.10FCVal 0.026 12.692 8.647 5.29e-18 0.027 13.609 11.997 3.69e-33
All.MultiPRS LDpred1.MultiPRS 0.020 9.894 8.540 1.34e-17 0.021 10.798 10.450 1.46e-25
All.MultiPRS LDpred1.Inf 0.040 19.882 13.511 1.34e-41 0.043 21.574 14.911 2.82e-50
All.MultiPRS LDpred2.10FCVal 0.006 3.005 2.056 3.98e-02 0.007 3.630 5.191 2.09e-07
All.MultiPRS LDpred2.MultiPRS 0.003 1.559 1.847 6.47e-02 0.004 1.989 3.895 9.83e-05
All.MultiPRS LDpred2.PseudoVal 0.032 15.899 10.803 3.34e-27 0.029 14.892 12.906 4.15e-38
All.MultiPRS LDpred2.Inf 0.042 20.641 14.031 1.01e-44 0.043 21.897 14.145 1.99e-45
All.MultiPRS DBSLMM.PseudoVal 0.019 9.273 6.325 2.53e-10 0.020 10.288 9.376 6.83e-21
All.MultiPRS All.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00

Show table: TEDS (1KG ref)

Average difference between methods in TEDS with 1KG reference
Reference Test CrossVal Diff CrossVal Diff (%) CrossVal Diff Z CrossVal Diff P IndepVal Diff IndepVal Diff (%) IndepVal Diff Z IndepVal Diff P
pT+clump.10FCVal pT+clump.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
pT+clump.10FCVal pT+clump.MultiPRS -0.007 -2.450 -0.651 5.15e-01 -0.015 -5.242 -3.302 9.60e-04
pT+clump.10FCVal lassosum.10FCVal -0.037 -12.753 -7.873 3.47e-15 -0.046 -16.458 -4.868 1.13e-06
pT+clump.10FCVal lassosum.MultiPRS -0.041 -14.173 -3.796 1.47e-04 -0.049 -17.504 -5.066 4.05e-07
pT+clump.10FCVal lassosum.PseudoVal 0.030 10.405 4.221 2.43e-05 0.034 12.244 2.364 1.81e-02
pT+clump.10FCVal PRScs.10FCVal -0.036 -12.253 -7.738 1.01e-14 -0.048 -17.323 -5.209 1.90e-07
pT+clump.10FCVal PRScs.MultiPRS -0.038 -13.036 -3.491 4.82e-04 -0.049 -17.502 -5.334 9.63e-08
pT+clump.10FCVal PRScs.PseudoVal -0.031 -10.801 -6.316 2.69e-10 -0.040 -14.492 -4.017 5.91e-05
pT+clump.10FCVal SBLUP.Inf -0.013 -4.610 -2.582 9.82e-03 -0.025 -8.842 -2.328 1.99e-02
pT+clump.10FCVal SBayesR.PseudoVal -0.023 -7.865 -3.861 1.13e-04 -0.024 -8.541 -2.008 4.46e-02
pT+clump.10FCVal LDpred1.10FCVal -0.018 -6.199 -3.412 6.45e-04 -0.024 -8.432 -2.182 2.91e-02
pT+clump.10FCVal LDpred1.MultiPRS -0.024 -8.198 -2.189 2.86e-02 -0.030 -10.647 -2.887 3.88e-03
pT+clump.10FCVal LDpred1.Inf -0.021 -7.055 -4.094 4.24e-05 -0.026 -9.419 -2.562 1.04e-02
pT+clump.10FCVal LDpred2.10FCVal -0.039 -13.519 -7.938 2.05e-15 -0.046 -16.649 -4.654 3.25e-06
pT+clump.10FCVal LDpred2.MultiPRS -0.040 -13.803 -3.700 2.15e-04 -0.041 -14.599 -4.107 4.01e-05
pT+clump.10FCVal LDpred2.PseudoVal -0.017 -5.854 -3.241 1.19e-03 -0.024 -8.698 -2.268 2.33e-02
pT+clump.10FCVal LDpred2.Inf -0.017 -5.959 -3.342 8.31e-04 -0.024 -8.525 -2.251 2.44e-02
pT+clump.10FCVal DBSLMM.PseudoVal -0.031 -10.509 -6.001 1.96e-09 -0.034 -12.239 -3.349 8.12e-04
pT+clump.10FCVal All.MultiPRS -0.046 -15.710 -4.227 2.36e-05 -0.047 -16.845 -4.893 9.92e-07
pT+clump.MultiPRS pT+clump.10FCVal 0.007 2.392 0.651 5.15e-01 0.015 4.981 3.302 9.60e-04
pT+clump.MultiPRS pT+clump.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
pT+clump.MultiPRS lassosum.10FCVal -0.030 -10.056 -2.770 5.61e-03 -0.031 -10.657 -3.681 2.32e-04
pT+clump.MultiPRS lassosum.MultiPRS -0.034 -11.443 -3.152 1.62e-03 -0.034 -11.651 -4.084 4.42e-05
pT+clump.MultiPRS lassosum.PseudoVal 0.037 12.548 3.394 6.88e-04 0.049 16.615 3.880 1.04e-04
pT+clump.MultiPRS PRScs.10FCVal -0.029 -9.568 -2.635 8.41e-03 -0.034 -11.480 -3.949 7.85e-05
pT+clump.MultiPRS PRScs.MultiPRS -0.031 -10.333 -2.855 4.30e-03 -0.034 -11.649 -4.283 1.84e-05
pT+clump.MultiPRS PRScs.PseudoVal -0.024 -8.151 -2.241 2.50e-02 -0.026 -8.789 -3.061 2.21e-03
pT+clump.MultiPRS SBLUP.Inf -0.006 -2.108 -0.576 5.65e-01 -0.010 -3.420 -1.014 3.10e-01
pT+clump.MultiPRS SBayesR.PseudoVal -0.016 -5.285 -1.450 1.47e-01 -0.009 -3.134 -0.889 3.74e-01
pT+clump.MultiPRS LDpred1.10FCVal -0.011 -3.659 -1.000 3.17e-01 -0.009 -3.031 -0.888 3.75e-01
pT+clump.MultiPRS LDpred1.MultiPRS -0.017 -5.610 -1.540 1.24e-01 -0.015 -5.136 -1.598 1.10e-01
pT+clump.MultiPRS LDpred1.Inf -0.013 -4.495 -1.231 2.18e-01 -0.012 -3.969 -1.221 2.22e-01
pT+clump.MultiPRS LDpred2.10FCVal -0.032 -10.804 -2.976 2.92e-03 -0.032 -10.839 -3.594 3.26e-04
pT+clump.MultiPRS LDpred2.MultiPRS -0.033 -11.081 -3.067 2.17e-03 -0.026 -8.891 -2.926 3.43e-03
pT+clump.MultiPRS LDpred2.PseudoVal -0.010 -3.322 -0.909 3.63e-01 -0.010 -3.284 -0.967 3.34e-01
pT+clump.MultiPRS LDpred2.Inf -0.010 -3.425 -0.937 3.49e-01 -0.009 -3.119 -0.929 3.53e-01
pT+clump.MultiPRS DBSLMM.PseudoVal -0.023 -7.866 -2.160 3.08e-02 -0.020 -6.648 -2.322 2.02e-02
pT+clump.MultiPRS All.MultiPRS -0.039 -12.943 -3.610 3.07e-04 -0.032 -11.025 -3.817 1.35e-04
lassosum.10FCVal pT+clump.10FCVal 0.037 11.311 7.873 3.47e-15 0.046 14.132 4.868 1.13e-06
lassosum.10FCVal pT+clump.MultiPRS 0.030 9.137 2.770 5.61e-03 0.031 9.631 3.681 2.32e-04
lassosum.10FCVal lassosum.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.10FCVal lassosum.MultiPRS -0.004 -1.260 -0.386 7.00e-01 -0.003 -0.899 -0.879 3.79e-01
lassosum.10FCVal lassosum.PseudoVal 0.067 20.539 12.555 3.73e-36 0.080 24.645 7.323 2.43e-13
lassosum.10FCVal PRScs.10FCVal 0.001 0.444 0.554 5.80e-01 -0.002 -0.743 -0.450 6.53e-01
lassosum.10FCVal PRScs.MultiPRS -0.001 -0.251 -0.077 9.39e-01 -0.003 -0.896 -0.629 5.29e-01
lassosum.10FCVal PRScs.PseudoVal 0.006 1.731 2.195 2.82e-02 0.005 1.688 1.043 2.97e-01
lassosum.10FCVal SBLUP.Inf 0.024 7.222 6.026 1.68e-09 0.021 6.540 2.709 6.75e-03
lassosum.10FCVal SBayesR.PseudoVal 0.014 4.335 3.387 7.07e-04 0.022 6.798 2.585 9.75e-03
lassosum.10FCVal LDpred1.10FCVal 0.019 5.812 5.036 4.76e-07 0.022 6.892 2.901 3.72e-03
lassosum.10FCVal LDpred1.MultiPRS 0.013 4.040 1.234 2.17e-01 0.016 4.990 2.301 2.14e-02
lassosum.10FCVal LDpred1.Inf 0.017 5.053 4.512 6.43e-06 0.020 6.044 2.618 8.84e-03
lassosum.10FCVal LDpred2.10FCVal -0.002 -0.680 -0.819 4.13e-01 -0.001 -0.164 -0.097 9.23e-01
lassosum.10FCVal LDpred2.MultiPRS -0.003 -0.931 -0.285 7.76e-01 0.005 1.596 0.915 3.60e-01
lassosum.10FCVal LDpred2.PseudoVal 0.020 6.119 5.293 1.20e-07 0.022 6.663 2.824 4.74e-03
lassosum.10FCVal LDpred2.Inf 0.020 6.026 5.260 1.44e-07 0.022 6.812 2.910 3.61e-03
lassosum.10FCVal DBSLMM.PseudoVal 0.007 1.990 1.867 6.19e-02 0.012 3.623 1.665 9.59e-02
lassosum.10FCVal All.MultiPRS -0.009 -2.623 -0.809 4.19e-01 -0.001 -0.333 -0.194 8.46e-01
lassosum.MultiPRS pT+clump.10FCVal 0.041 12.414 3.796 1.47e-04 0.049 14.897 5.066 4.05e-07
lassosum.MultiPRS pT+clump.MultiPRS 0.034 10.268 3.152 1.62e-03 0.034 10.435 4.084 4.42e-05
lassosum.MultiPRS lassosum.10FCVal 0.004 1.244 0.386 7.00e-01 0.003 0.891 0.879 3.79e-01
lassosum.MultiPRS lassosum.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.MultiPRS lassosum.PseudoVal 0.071 21.528 6.547 5.86e-11 0.083 25.316 7.541 4.67e-14
lassosum.MultiPRS PRScs.10FCVal 0.006 1.682 0.521 6.02e-01 0.001 0.154 0.098 9.22e-01
lassosum.MultiPRS PRScs.MultiPRS 0.003 0.996 0.448 6.54e-01 0.000 0.002 0.002 9.99e-01
lassosum.MultiPRS PRScs.PseudoVal 0.010 2.954 0.913 3.61e-01 0.008 2.564 1.633 1.02e-01
lassosum.MultiPRS SBLUP.Inf 0.028 8.376 2.568 1.02e-02 0.024 7.372 3.184 1.45e-03
lassosum.MultiPRS SBayesR.PseudoVal 0.018 5.525 1.705 8.82e-02 0.025 7.628 2.974 2.94e-03
lassosum.MultiPRS LDpred1.10FCVal 0.023 6.984 2.147 3.18e-02 0.025 7.721 3.401 6.72e-04
lassosum.MultiPRS LDpred1.MultiPRS 0.017 5.234 2.297 2.16e-02 0.019 5.836 2.824 4.75e-03
lassosum.MultiPRS LDpred1.Inf 0.021 6.234 1.917 5.53e-02 0.023 6.881 3.115 1.84e-03
lassosum.MultiPRS LDpred2.10FCVal 0.002 0.573 0.177 8.59e-01 0.002 0.728 0.445 6.56e-01
lassosum.MultiPRS LDpred2.MultiPRS 0.001 0.325 0.155 8.77e-01 0.008 2.472 1.459 1.45e-01
lassosum.MultiPRS LDpred2.PseudoVal 0.024 7.287 2.237 2.53e-02 0.025 7.495 3.315 9.16e-04
lassosum.MultiPRS LDpred2.Inf 0.024 7.195 2.209 2.72e-02 0.025 7.642 3.409 6.53e-04
lassosum.MultiPRS DBSLMM.PseudoVal 0.011 3.210 0.994 3.20e-01 0.015 4.481 2.392 1.68e-02
lassosum.MultiPRS All.MultiPRS -0.004 -1.346 -0.421 6.73e-01 0.002 0.561 0.425 6.71e-01
lassosum.PseudoVal pT+clump.10FCVal -0.030 -11.614 -4.221 2.43e-05 -0.034 -13.952 -2.364 1.81e-02
lassosum.PseudoVal pT+clump.MultiPRS -0.037 -14.349 -3.394 6.88e-04 -0.049 -19.925 -3.880 1.04e-04
lassosum.PseudoVal lassosum.10FCVal -0.067 -25.848 -12.555 3.73e-36 -0.080 -32.706 -7.323 2.43e-13
lassosum.PseudoVal lassosum.MultiPRS -0.071 -27.433 -6.547 5.86e-11 -0.083 -33.898 -7.541 4.67e-14
lassosum.PseudoVal lassosum.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.PseudoVal PRScs.10FCVal -0.066 -25.289 -11.309 1.19e-29 -0.082 -33.692 -6.927 4.29e-12
lassosum.PseudoVal PRScs.MultiPRS -0.068 -26.164 -6.272 3.58e-10 -0.083 -33.895 -7.374 1.65e-13
lassosum.PseudoVal PRScs.PseudoVal -0.062 -23.669 -12.255 1.57e-34 -0.075 -30.466 -7.446 9.64e-14
lassosum.PseudoVal SBLUP.Inf -0.044 -16.760 -5.991 2.09e-09 -0.059 -24.027 -4.016 5.93e-05
lassosum.PseudoVal SBayesR.PseudoVal -0.053 -20.392 -10.739 6.69e-27 -0.058 -23.684 -5.743 9.32e-09
lassosum.PseudoVal LDpred1.10FCVal -0.048 -18.533 -7.027 2.11e-12 -0.058 -23.560 -4.144 3.41e-05
lassosum.PseudoVal LDpred1.MultiPRS -0.054 -20.764 -4.956 7.21e-07 -0.064 -26.084 -4.659 3.17e-06
lassosum.PseudoVal LDpred1.Inf -0.051 -19.489 -7.198 6.12e-13 -0.060 -24.685 -4.217 2.47e-05
lassosum.PseudoVal LDpred2.10FCVal -0.070 -26.703 -11.687 1.48e-31 -0.081 -32.924 -6.717 1.85e-11
lassosum.PseudoVal LDpred2.MultiPRS -0.070 -27.019 -6.446 1.15e-10 -0.075 -30.588 -6.375 1.83e-10
lassosum.PseudoVal LDpred2.PseudoVal -0.047 -18.147 -6.658 2.78e-11 -0.058 -23.863 -4.069 4.73e-05
lassosum.PseudoVal LDpred2.Inf -0.048 -18.265 -6.693 2.19e-11 -0.058 -23.666 -4.032 5.54e-05
lassosum.PseudoVal DBSLMM.PseudoVal -0.061 -23.343 -10.096 5.76e-24 -0.068 -27.898 -5.597 2.17e-08
lassosum.PseudoVal All.MultiPRS -0.076 -29.148 -7.016 2.28e-12 -0.081 -33.147 -7.041 1.91e-12
PRScs.10FCVal pT+clump.10FCVal 0.036 10.915 7.738 1.01e-14 0.048 14.766 5.209 1.90e-07
PRScs.10FCVal pT+clump.MultiPRS 0.029 8.732 2.635 8.41e-03 0.034 10.297 3.949 7.85e-05
PRScs.10FCVal lassosum.10FCVal -0.001 -0.446 -0.554 5.80e-01 0.002 0.738 0.450 6.53e-01
PRScs.10FCVal lassosum.MultiPRS -0.006 -1.711 -0.521 6.02e-01 -0.001 -0.154 -0.098 9.22e-01
PRScs.10FCVal lassosum.PseudoVal 0.066 20.185 11.309 1.19e-29 0.082 25.201 6.927 4.29e-12
PRScs.10FCVal PRScs.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
PRScs.10FCVal PRScs.MultiPRS -0.002 -0.698 -0.213 8.31e-01 0.000 -0.152 -0.205 8.37e-01
PRScs.10FCVal PRScs.PseudoVal 0.004 1.293 1.697 8.98e-02 0.008 2.413 1.529 1.26e-01
PRScs.10FCVal SBLUP.Inf 0.022 6.808 6.677 2.44e-11 0.024 7.229 3.506 4.55e-04
PRScs.10FCVal SBayesR.PseudoVal 0.013 3.909 2.864 4.18e-03 0.024 7.486 2.707 6.80e-03
PRScs.10FCVal LDpred1.10FCVal 0.018 5.393 5.523 3.33e-08 0.025 7.579 3.801 1.44e-04
PRScs.10FCVal LDpred1.MultiPRS 0.012 3.612 1.098 2.72e-01 0.019 5.691 3.286 1.02e-03
PRScs.10FCVal LDpred1.Inf 0.015 4.630 5.044 4.57e-07 0.022 6.737 3.661 2.51e-04
PRScs.10FCVal LDpred2.10FCVal -0.004 -1.128 -1.428 1.53e-01 0.002 0.575 0.358 7.21e-01
PRScs.10FCVal LDpred2.MultiPRS -0.005 -1.381 -0.421 6.74e-01 0.008 2.322 1.430 1.53e-01
PRScs.10FCVal LDpred2.PseudoVal 0.019 5.700 5.895 3.75e-09 0.024 7.352 3.762 1.69e-04
PRScs.10FCVal LDpred2.Inf 0.018 5.607 5.857 4.71e-09 0.025 7.499 3.881 1.04e-04
PRScs.10FCVal DBSLMM.PseudoVal 0.005 1.553 1.698 8.95e-02 0.014 4.334 2.360 1.83e-02
PRScs.10FCVal All.MultiPRS -0.010 -3.080 -0.944 3.45e-01 0.001 0.408 0.237 8.13e-01
PRScs.MultiPRS pT+clump.10FCVal 0.038 11.533 3.491 4.82e-04 0.049 14.895 5.334 9.63e-08
PRScs.MultiPRS pT+clump.MultiPRS 0.031 9.365 2.855 4.30e-03 0.034 10.433 4.283 1.84e-05
PRScs.MultiPRS lassosum.10FCVal 0.001 0.251 0.077 9.39e-01 0.003 0.888 0.629 5.29e-01
PRScs.MultiPRS lassosum.MultiPRS -0.003 -1.006 -0.448 6.54e-01 0.000 -0.002 -0.002 9.99e-01
PRScs.MultiPRS lassosum.PseudoVal 0.068 20.738 6.272 3.58e-10 0.083 25.315 7.374 1.65e-13
PRScs.MultiPRS PRScs.10FCVal 0.002 0.693 0.213 8.31e-01 0.000 0.152 0.205 8.37e-01
PRScs.MultiPRS PRScs.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
PRScs.MultiPRS PRScs.PseudoVal 0.007 1.978 0.607 5.44e-01 0.008 2.561 2.229 2.58e-02
PRScs.MultiPRS SBLUP.Inf 0.025 7.454 2.267 2.34e-02 0.024 7.370 3.772 1.62e-04
PRScs.MultiPRS SBayesR.PseudoVal 0.015 4.575 1.404 1.60e-01 0.025 7.626 3.017 2.56e-03
PRScs.MultiPRS LDpred1.10FCVal 0.020 6.049 1.843 6.54e-02 0.025 7.719 3.981 6.86e-05
PRScs.MultiPRS LDpred1.MultiPRS 0.014 4.280 2.714 6.64e-03 0.019 5.834 3.528 4.19e-04
PRScs.MultiPRS LDpred1.Inf 0.017 5.291 1.615 1.06e-01 0.023 6.879 3.888 1.01e-04
PRScs.MultiPRS LDpred2.10FCVal -0.001 -0.427 -0.131 8.95e-01 0.002 0.726 0.515 6.06e-01
PRScs.MultiPRS LDpred2.MultiPRS -0.002 -0.678 -0.251 8.02e-01 0.008 2.470 1.675 9.38e-02
PRScs.MultiPRS LDpred2.PseudoVal 0.021 6.354 1.937 5.27e-02 0.025 7.492 3.966 7.30e-05
PRScs.MultiPRS LDpred2.Inf 0.021 6.261 1.908 5.64e-02 0.025 7.640 4.121 3.78e-05
PRScs.MultiPRS DBSLMM.PseudoVal 0.007 2.236 0.686 4.93e-01 0.015 4.479 2.682 7.33e-03
PRScs.MultiPRS All.MultiPRS -0.008 -2.365 -1.066 2.86e-01 0.002 0.559 0.364 7.16e-01
PRScs.PseudoVal pT+clump.10FCVal 0.031 9.748 6.316 2.69e-10 0.040 12.658 4.017 5.91e-05
PRScs.PseudoVal pT+clump.MultiPRS 0.024 7.536 2.241 2.50e-02 0.026 8.079 3.061 2.21e-03
PRScs.PseudoVal lassosum.10FCVal -0.006 -1.762 -2.195 2.82e-02 -0.005 -1.717 -1.043 2.97e-01
PRScs.PseudoVal lassosum.MultiPRS -0.010 -3.044 -0.913 3.61e-01 -0.008 -2.631 -1.633 1.02e-01
PRScs.PseudoVal lassosum.PseudoVal 0.062 19.139 12.255 1.57e-34 0.075 23.352 7.446 9.64e-14
PRScs.PseudoVal PRScs.10FCVal -0.004 -1.310 -1.697 8.98e-02 -0.008 -2.473 -1.529 1.26e-01
PRScs.PseudoVal PRScs.MultiPRS -0.007 -2.018 -0.607 5.44e-01 -0.008 -2.629 -2.229 2.58e-02
PRScs.PseudoVal PRScs.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
PRScs.PseudoVal SBLUP.Inf 0.018 5.587 4.776 1.79e-06 0.016 4.935 2.038 4.16e-02
PRScs.PseudoVal SBayesR.PseudoVal 0.009 2.650 2.275 2.29e-02 0.017 5.198 2.215 2.67e-02
PRScs.PseudoVal LDpred1.10FCVal 0.013 4.153 3.715 2.03e-04 0.017 5.293 2.255 2.41e-02
PRScs.PseudoVal LDpred1.MultiPRS 0.008 2.349 0.704 4.81e-01 0.011 3.358 1.593 1.11e-01
PRScs.PseudoVal LDpred1.Inf 0.011 3.380 3.175 1.50e-03 0.014 4.431 1.976 4.81e-02
PRScs.PseudoVal LDpred2.10FCVal -0.008 -2.453 -3.054 2.26e-03 -0.006 -1.884 -1.151 2.50e-01
PRScs.PseudoVal LDpred2.MultiPRS -0.009 -2.709 -0.813 4.16e-01 0.000 -0.094 -0.055 9.56e-01
PRScs.PseudoVal LDpred2.PseudoVal 0.014 4.465 4.064 4.82e-05 0.016 5.061 2.209 2.72e-02
PRScs.PseudoVal LDpred2.Inf 0.014 4.370 3.996 6.44e-05 0.017 5.212 2.286 2.23e-02
PRScs.PseudoVal DBSLMM.PseudoVal 0.001 0.264 0.280 7.79e-01 0.006 1.968 1.018 3.09e-01
PRScs.PseudoVal All.MultiPRS -0.014 -4.431 -1.341 1.80e-01 -0.007 -2.055 -1.121 2.62e-01
SBLUP.Inf pT+clump.10FCVal 0.013 4.407 2.582 9.82e-03 0.025 8.123 2.328 1.99e-02
SBLUP.Inf pT+clump.MultiPRS 0.006 2.065 0.576 5.65e-01 0.010 3.307 1.014 3.10e-01
SBLUP.Inf lassosum.10FCVal -0.024 -7.784 -6.026 1.68e-09 -0.021 -6.997 -2.709 6.75e-03
SBLUP.Inf lassosum.MultiPRS -0.028 -9.142 -2.568 1.02e-02 -0.024 -7.959 -3.184 1.45e-03
SBLUP.Inf lassosum.PseudoVal 0.044 14.354 5.991 2.09e-09 0.059 19.372 4.016 5.93e-05
SBLUP.Inf PRScs.10FCVal -0.022 -7.305 -6.677 2.44e-11 -0.024 -7.793 -3.506 4.55e-04
SBLUP.Inf PRScs.MultiPRS -0.025 -8.055 -2.267 2.34e-02 -0.024 -7.956 -3.772 1.62e-04
SBLUP.Inf PRScs.PseudoVal -0.018 -5.918 -4.776 1.79e-06 -0.016 -5.191 -2.038 4.16e-02
SBLUP.Inf SBLUP.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBLUP.Inf SBayesR.PseudoVal -0.009 -3.111 -1.704 8.83e-02 0.001 0.276 0.075 9.41e-01
SBLUP.Inf LDpred1.10FCVal -0.005 -1.519 -1.650 9.89e-02 0.001 0.376 0.198 8.43e-01
SBLUP.Inf LDpred1.MultiPRS -0.010 -3.429 -0.961 3.37e-01 -0.005 -1.659 -1.057 2.91e-01
SBLUP.Inf LDpred1.Inf -0.007 -2.337 -3.294 9.87e-04 -0.002 -0.531 -0.357 7.21e-01
SBLUP.Inf LDpred2.10FCVal -0.026 -8.516 -8.507 1.79e-17 -0.022 -7.173 -3.547 3.90e-04
SBLUP.Inf LDpred2.MultiPRS -0.027 -8.787 -2.474 1.34e-02 -0.016 -5.290 -2.324 2.01e-02
SBLUP.Inf LDpred2.PseudoVal -0.004 -1.189 -1.567 1.17e-01 0.000 0.132 0.084 9.33e-01
SBLUP.Inf LDpred2.Inf -0.004 -1.289 -1.747 8.06e-02 0.001 0.291 0.189 8.50e-01
SBLUP.Inf DBSLMM.PseudoVal -0.017 -5.639 -4.706 2.52e-06 -0.009 -3.121 -1.261 2.07e-01
SBLUP.Inf All.MultiPRS -0.032 -10.611 -3.001 2.69e-03 -0.022 -7.353 -2.940 3.29e-03
SBayesR.PseudoVal pT+clump.10FCVal 0.023 7.292 3.861 1.13e-04 0.024 7.869 2.008 4.46e-02
SBayesR.PseudoVal pT+clump.MultiPRS 0.016 5.020 1.450 1.47e-01 0.009 3.039 0.889 3.74e-01
SBayesR.PseudoVal lassosum.10FCVal -0.014 -4.531 -3.387 7.07e-04 -0.022 -7.294 -2.585 9.75e-03
SBayesR.PseudoVal lassosum.MultiPRS -0.018 -5.848 -1.705 8.82e-02 -0.025 -8.258 -2.974 2.94e-03
SBayesR.PseudoVal lassosum.PseudoVal 0.053 16.938 10.739 6.69e-27 0.058 19.149 5.743 9.32e-09
SBayesR.PseudoVal PRScs.10FCVal -0.013 -4.067 -2.864 4.18e-03 -0.024 -8.092 -2.707 6.80e-03
SBayesR.PseudoVal PRScs.MultiPRS -0.015 -4.794 -1.404 1.60e-01 -0.025 -8.256 -3.017 2.56e-03
SBayesR.PseudoVal PRScs.PseudoVal -0.009 -2.722 -2.275 2.29e-02 -0.017 -5.483 -2.215 2.67e-02
SBayesR.PseudoVal SBLUP.Inf 0.009 3.018 1.704 8.83e-02 -0.001 -0.277 -0.075 9.41e-01
SBayesR.PseudoVal SBayesR.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBayesR.PseudoVal LDpred1.10FCVal 0.005 1.544 0.893 3.72e-01 0.000 0.100 0.027 9.78e-01
SBayesR.PseudoVal LDpred1.MultiPRS -0.001 -0.308 -0.090 9.28e-01 -0.006 -1.940 -0.553 5.80e-01
SBayesR.PseudoVal LDpred1.Inf 0.002 0.751 0.438 6.61e-01 -0.002 -0.809 -0.223 8.24e-01
SBayesR.PseudoVal LDpred2.10FCVal -0.016 -5.242 -3.788 1.52e-04 -0.023 -7.470 -2.561 1.04e-02
SBayesR.PseudoVal LDpred2.MultiPRS -0.017 -5.505 -1.603 1.09e-01 -0.017 -5.582 -1.951 5.11e-02
SBayesR.PseudoVal LDpred2.PseudoVal 0.006 1.865 1.089 2.76e-01 0.000 -0.145 -0.040 9.68e-01
SBayesR.PseudoVal LDpred2.Inf 0.006 1.767 1.032 3.02e-01 0.000 0.015 0.004 9.97e-01
SBayesR.PseudoVal DBSLMM.PseudoVal -0.008 -2.451 -1.721 8.53e-02 -0.010 -3.407 -1.140 2.54e-01
SBayesR.PseudoVal All.MultiPRS -0.023 -7.273 -2.140 3.24e-02 -0.023 -7.651 -2.849 4.39e-03
LDpred1.10FCVal pT+clump.10FCVal 0.018 5.837 3.412 6.45e-04 0.024 7.776 2.182 2.91e-02
LDpred1.10FCVal pT+clump.MultiPRS 0.011 3.530 1.000 3.17e-01 0.009 2.942 0.888 3.75e-01
LDpred1.10FCVal lassosum.10FCVal -0.019 -6.171 -5.036 4.76e-07 -0.022 -7.402 -2.901 3.72e-03
LDpred1.10FCVal lassosum.MultiPRS -0.023 -7.509 -2.147 3.18e-02 -0.025 -8.367 -3.401 6.72e-04
LDpred1.10FCVal lassosum.PseudoVal 0.048 15.635 7.027 2.11e-12 0.058 19.068 4.144 3.41e-05
LDpred1.10FCVal PRScs.10FCVal -0.018 -5.700 -5.523 3.33e-08 -0.025 -8.200 -3.801 1.44e-04
LDpred1.10FCVal PRScs.MultiPRS -0.020 -6.438 -1.843 6.54e-02 -0.025 -8.364 -3.981 6.86e-05
LDpred1.10FCVal PRScs.PseudoVal -0.013 -4.333 -3.715 2.03e-04 -0.017 -5.589 -2.255 2.41e-02
LDpred1.10FCVal SBLUP.Inf 0.005 1.496 1.650 9.89e-02 -0.001 -0.378 -0.198 8.43e-01
LDpred1.10FCVal SBayesR.PseudoVal -0.005 -1.569 -0.893 3.72e-01 0.000 -0.100 -0.027 9.78e-01
LDpred1.10FCVal LDpred1.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.10FCVal LDpred1.MultiPRS -0.006 -1.882 -0.536 5.92e-01 -0.006 -2.043 -1.903 5.71e-02
LDpred1.10FCVal LDpred1.Inf -0.002 -0.806 -1.012 3.11e-01 -0.003 -0.911 -0.546 5.85e-01
LDpred1.10FCVal LDpred2.10FCVal -0.021 -6.893 -7.013 2.33e-12 -0.023 -7.578 -3.691 2.23e-04
LDpred1.10FCVal LDpred2.MultiPRS -0.022 -7.160 -2.047 4.07e-02 -0.017 -5.688 -2.509 1.21e-02
LDpred1.10FCVal LDpred2.PseudoVal 0.001 0.325 0.354 7.23e-01 -0.001 -0.245 -0.128 8.98e-01
LDpred1.10FCVal LDpred2.Inf 0.001 0.226 0.247 8.05e-01 0.000 -0.086 -0.045 9.64e-01
LDpred1.10FCVal DBSLMM.PseudoVal -0.013 -4.058 -3.406 6.58e-04 -0.011 -3.511 -1.389 1.65e-01
LDpred1.10FCVal All.MultiPRS -0.028 -8.956 -2.576 1.00e-02 -0.023 -7.759 -3.205 1.35e-03
LDpred1.MultiPRS pT+clump.10FCVal 0.024 7.577 2.189 2.86e-02 0.030 9.622 2.887 3.88e-03
LDpred1.MultiPRS pT+clump.MultiPRS 0.017 5.312 1.540 1.24e-01 0.015 4.885 1.598 1.10e-01
LDpred1.MultiPRS lassosum.10FCVal -0.013 -4.210 -1.234 2.17e-01 -0.016 -5.252 -2.301 2.14e-02
LDpred1.MultiPRS lassosum.MultiPRS -0.017 -5.523 -2.297 2.16e-02 -0.019 -6.197 -2.824 4.75e-03
LDpred1.MultiPRS lassosum.PseudoVal 0.054 17.194 4.956 7.21e-07 0.064 20.688 4.659 3.17e-06
LDpred1.MultiPRS PRScs.10FCVal -0.012 -3.748 -1.098 2.72e-01 -0.019 -6.034 -3.286 1.02e-03
LDpred1.MultiPRS PRScs.MultiPRS -0.014 -4.472 -2.714 6.64e-03 -0.019 -6.195 -3.528 4.19e-04
LDpred1.MultiPRS PRScs.PseudoVal -0.008 -2.406 -0.704 4.81e-01 -0.011 -3.475 -1.593 1.11e-01
LDpred1.MultiPRS SBLUP.Inf 0.010 3.316 0.961 3.37e-01 0.005 1.632 1.057 2.91e-01
LDpred1.MultiPRS SBayesR.PseudoVal 0.001 0.307 0.090 9.28e-01 0.006 1.903 0.553 5.80e-01
LDpred1.MultiPRS LDpred1.10FCVal 0.006 1.847 0.536 5.92e-01 0.006 2.002 1.903 5.71e-02
LDpred1.MultiPRS LDpred1.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.MultiPRS LDpred1.Inf 0.003 1.056 0.307 7.59e-01 0.003 1.110 1.125 2.61e-01
LDpred1.MultiPRS LDpred2.10FCVal -0.015 -4.918 -1.441 1.50e-01 -0.017 -5.424 -3.206 1.35e-03
LDpred1.MultiPRS LDpred2.MultiPRS -0.016 -5.180 -1.833 6.68e-02 -0.011 -3.572 -1.825 6.80e-02
LDpred1.MultiPRS LDpred2.PseudoVal 0.007 2.167 0.629 5.29e-01 0.005 1.762 1.194 2.32e-01
LDpred1.MultiPRS LDpred2.Inf 0.007 2.069 0.601 5.48e-01 0.006 1.918 1.308 1.91e-01
LDpred1.MultiPRS DBSLMM.PseudoVal -0.007 -2.136 -0.625 5.32e-01 -0.004 -1.439 -0.647 5.18e-01
LDpred1.MultiPRS All.MultiPRS -0.022 -6.943 -2.461 1.38e-02 -0.017 -5.602 -2.653 7.98e-03
LDpred1.Inf pT+clump.10FCVal 0.021 6.590 4.094 4.24e-05 0.026 8.608 2.562 1.04e-02
LDpred1.Inf pT+clump.MultiPRS 0.013 4.301 1.231 2.18e-01 0.012 3.817 1.221 2.22e-01
LDpred1.Inf lassosum.10FCVal -0.017 -5.322 -4.512 6.43e-06 -0.020 -6.433 -2.618 8.84e-03
LDpred1.Inf lassosum.MultiPRS -0.021 -6.649 -1.917 5.53e-02 -0.023 -7.389 -3.115 1.84e-03
LDpred1.Inf lassosum.PseudoVal 0.051 16.310 7.198 6.12e-13 0.060 19.798 4.217 2.47e-05
LDpred1.Inf PRScs.10FCVal -0.015 -4.855 -5.044 4.57e-07 -0.022 -7.224 -3.661 2.51e-04
LDpred1.Inf PRScs.MultiPRS -0.017 -5.587 -1.615 1.06e-01 -0.023 -7.387 -3.888 1.01e-04
LDpred1.Inf PRScs.PseudoVal -0.011 -3.499 -3.175 1.50e-03 -0.014 -4.636 -1.976 4.81e-02
LDpred1.Inf SBLUP.Inf 0.007 2.284 3.294 9.87e-04 0.002 0.528 0.357 7.21e-01
LDpred1.Inf SBayesR.PseudoVal -0.002 -0.756 -0.438 6.61e-01 0.002 0.803 0.223 8.24e-01
LDpred1.Inf LDpred1.10FCVal 0.002 0.800 1.012 3.11e-01 0.003 0.902 0.546 5.85e-01
LDpred1.Inf LDpred1.MultiPRS -0.003 -1.067 -0.307 7.59e-01 -0.003 -1.122 -1.125 2.61e-01
LDpred1.Inf LDpred1.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.Inf LDpred2.10FCVal -0.019 -6.038 -6.879 6.02e-12 -0.020 -6.607 -3.603 3.14e-04
LDpred1.Inf LDpred2.MultiPRS -0.020 -6.303 -1.821 6.86e-02 -0.014 -4.734 -2.254 2.42e-02
LDpred1.Inf LDpred2.PseudoVal 0.003 1.123 1.779 7.53e-02 0.002 0.659 0.505 6.13e-01
LDpred1.Inf LDpred2.Inf 0.003 1.024 1.642 1.01e-01 0.002 0.817 0.634 5.26e-01
LDpred1.Inf DBSLMM.PseudoVal -0.010 -3.226 -2.950 3.18e-03 -0.008 -2.577 -1.113 2.66e-01
LDpred1.Inf All.MultiPRS -0.025 -8.084 -2.348 1.89e-02 -0.021 -6.787 -2.908 3.64e-03
LDpred2.10FCVal pT+clump.10FCVal 0.039 11.909 7.938 2.05e-15 0.046 14.273 4.654 3.25e-06
LDpred2.10FCVal pT+clump.MultiPRS 0.032 9.751 2.976 2.92e-03 0.032 9.779 3.594 3.26e-04
LDpred2.10FCVal lassosum.10FCVal 0.002 0.675 0.819 4.13e-01 0.001 0.164 0.097 9.23e-01
LDpred2.10FCVal lassosum.MultiPRS -0.002 -0.576 -0.177 8.59e-01 -0.002 -0.733 -0.445 6.56e-01
LDpred2.10FCVal lassosum.PseudoVal 0.070 21.075 11.687 1.48e-31 0.081 24.769 6.717 1.85e-11
LDpred2.10FCVal PRScs.10FCVal 0.004 1.116 1.428 1.53e-01 -0.002 -0.578 -0.358 7.21e-01
LDpred2.10FCVal PRScs.MultiPRS 0.001 0.425 0.131 8.95e-01 -0.002 -0.731 -0.515 6.06e-01
LDpred2.10FCVal PRScs.PseudoVal 0.008 2.395 3.054 2.26e-03 0.006 1.849 1.151 2.50e-01
LDpred2.10FCVal SBLUP.Inf 0.026 7.848 8.507 1.79e-17 0.022 6.693 3.547 3.90e-04
LDpred2.10FCVal SBayesR.PseudoVal 0.016 4.981 3.788 1.52e-04 0.023 6.951 2.561 1.04e-02
LDpred2.10FCVal LDpred1.10FCVal 0.021 6.448 7.013 2.33e-12 0.023 7.044 3.691 2.23e-04
LDpred2.10FCVal LDpred1.MultiPRS 0.015 4.688 1.441 1.50e-01 0.017 5.145 3.206 1.35e-03
LDpred2.10FCVal LDpred1.Inf 0.019 5.694 6.879 6.02e-12 0.020 6.198 3.603 3.14e-04
LDpred2.10FCVal LDpred2.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.10FCVal LDpred2.MultiPRS -0.001 -0.250 -0.077 9.39e-01 0.006 1.757 2.344 1.91e-02
LDpred2.10FCVal LDpred2.PseudoVal 0.022 6.753 10.504 8.27e-26 0.022 6.816 5.125 2.97e-07
LDpred2.10FCVal LDpred2.Inf 0.022 6.660 10.381 3.04e-25 0.023 6.965 5.248 1.53e-07
LDpred2.10FCVal DBSLMM.PseudoVal 0.009 2.652 2.776 5.51e-03 0.012 3.781 1.916 5.53e-02
LDpred2.10FCVal All.MultiPRS -0.006 -1.930 -0.599 5.49e-01 -0.001 -0.168 -0.108 9.14e-01
LDpred2.MultiPRS pT+clump.10FCVal 0.040 12.129 3.700 2.15e-04 0.041 12.739 4.107 4.01e-05
LDpred2.MultiPRS pT+clump.MultiPRS 0.033 9.975 3.067 2.17e-03 0.026 8.165 2.926 3.43e-03
LDpred2.MultiPRS lassosum.10FCVal 0.003 0.922 0.285 7.76e-01 -0.005 -1.622 -0.915 3.60e-01
LDpred2.MultiPRS lassosum.MultiPRS -0.001 -0.326 -0.155 8.77e-01 -0.008 -2.535 -1.459 1.45e-01
LDpred2.MultiPRS lassosum.PseudoVal 0.070 21.272 6.446 1.15e-10 0.075 23.423 6.375 1.83e-10
LDpred2.MultiPRS PRScs.10FCVal 0.005 1.362 0.421 6.74e-01 -0.008 -2.377 -1.430 1.53e-01
LDpred2.MultiPRS PRScs.MultiPRS 0.002 0.673 0.251 8.02e-01 -0.008 -2.533 -1.675 9.38e-02
LDpred2.MultiPRS PRScs.PseudoVal 0.009 2.638 0.813 4.16e-01 0.000 0.094 0.055 9.56e-01
LDpred2.MultiPRS SBLUP.Inf 0.027 8.077 2.474 1.34e-02 0.016 5.024 2.324 2.01e-02
LDpred2.MultiPRS SBayesR.PseudoVal 0.017 5.217 1.603 1.09e-01 0.017 5.287 1.951 5.11e-02
LDpred2.MultiPRS LDpred1.10FCVal 0.022 6.681 2.047 4.07e-02 0.017 5.382 2.509 1.21e-02
LDpred2.MultiPRS LDpred1.MultiPRS 0.016 4.925 1.833 6.68e-02 0.011 3.449 1.825 6.80e-02
LDpred2.MultiPRS LDpred1.Inf 0.020 5.929 1.821 6.86e-02 0.014 4.520 2.254 2.42e-02
LDpred2.MultiPRS LDpred2.10FCVal 0.001 0.249 0.077 9.39e-01 -0.006 -1.789 -2.344 1.91e-02
LDpred2.MultiPRS LDpred2.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.MultiPRS LDpred2.PseudoVal 0.023 6.985 2.142 3.22e-02 0.016 5.150 3.078 2.09e-03
LDpred2.MultiPRS LDpred2.Inf 0.023 6.892 2.113 3.46e-02 0.017 5.301 3.188 1.43e-03
LDpred2.MultiPRS DBSLMM.PseudoVal 0.010 2.894 0.893 3.72e-01 0.007 2.060 0.987 3.24e-01
LDpred2.MultiPRS All.MultiPRS -0.006 -1.676 -0.630 5.29e-01 -0.006 -1.960 -1.308 1.91e-01
LDpred2.PseudoVal pT+clump.10FCVal 0.017 5.530 3.241 1.19e-03 0.024 8.002 2.268 2.33e-02
LDpred2.PseudoVal pT+clump.MultiPRS 0.010 3.215 0.909 3.63e-01 0.010 3.179 0.967 3.34e-01
LDpred2.PseudoVal lassosum.10FCVal -0.020 -6.518 -5.293 1.20e-07 -0.022 -7.139 -2.824 4.74e-03
LDpred2.PseudoVal lassosum.MultiPRS -0.024 -7.860 -2.237 2.53e-02 -0.025 -8.102 -3.315 9.16e-04
LDpred2.PseudoVal lassosum.PseudoVal 0.047 15.360 6.658 2.78e-11 0.058 19.266 4.069 4.73e-05
LDpred2.PseudoVal PRScs.10FCVal -0.019 -6.045 -5.895 3.75e-09 -0.024 -7.935 -3.762 1.69e-04
LDpred2.PseudoVal PRScs.MultiPRS -0.021 -6.785 -1.937 5.27e-02 -0.025 -8.099 -3.966 7.30e-05
LDpred2.PseudoVal PRScs.PseudoVal -0.014 -4.674 -4.064 4.82e-05 -0.016 -5.330 -2.209 2.72e-02
LDpred2.PseudoVal SBLUP.Inf 0.004 1.175 1.567 1.17e-01 0.000 -0.132 -0.084 9.33e-01
LDpred2.PseudoVal SBayesR.PseudoVal -0.006 -1.900 -1.089 2.76e-01 0.000 0.145 0.040 9.68e-01
LDpred2.PseudoVal LDpred1.10FCVal -0.001 -0.326 -0.354 7.23e-01 0.001 0.245 0.128 8.98e-01
LDpred2.PseudoVal LDpred1.MultiPRS -0.007 -2.215 -0.629 5.29e-01 -0.005 -1.793 -1.194 2.32e-01
LDpred2.PseudoVal LDpred1.Inf -0.003 -1.135 -1.779 7.53e-02 -0.002 -0.664 -0.505 6.13e-01
LDpred2.PseudoVal LDpred2.10FCVal -0.022 -7.242 -10.504 8.27e-26 -0.022 -7.315 -5.125 2.97e-07
LDpred2.PseudoVal LDpred2.MultiPRS -0.023 -7.509 -2.142 3.22e-02 -0.016 -5.429 -3.078 2.09e-03
LDpred2.PseudoVal LDpred2.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.PseudoVal LDpred2.Inf 0.000 -0.100 -0.811 4.17e-01 0.000 0.159 0.637 5.24e-01
LDpred2.PseudoVal DBSLMM.PseudoVal -0.014 -4.398 -3.830 1.28e-04 -0.010 -3.257 -1.358 1.74e-01
LDpred2.PseudoVal All.MultiPRS -0.029 -9.311 -2.668 7.63e-03 -0.023 -7.495 -3.236 1.21e-03
LDpred2.Inf pT+clump.10FCVal 0.017 5.624 3.342 8.31e-04 0.024 7.855 2.251 2.44e-02
LDpred2.Inf pT+clump.MultiPRS 0.010 3.311 0.937 3.49e-01 0.009 3.025 0.929 3.53e-01
LDpred2.Inf lassosum.10FCVal -0.020 -6.412 -5.260 1.44e-07 -0.022 -7.310 -2.910 3.61e-03
LDpred2.Inf lassosum.MultiPRS -0.024 -7.752 -2.209 2.72e-02 -0.025 -8.274 -3.409 6.53e-04
LDpred2.Inf lassosum.PseudoVal 0.048 15.444 6.693 2.19e-11 0.058 19.137 4.032 5.54e-05
LDpred2.Inf PRScs.10FCVal -0.018 -5.940 -5.857 4.71e-09 -0.025 -8.108 -3.881 1.04e-04
LDpred2.Inf PRScs.MultiPRS -0.021 -6.679 -1.908 5.64e-02 -0.025 -8.272 -4.121 3.78e-05
LDpred2.Inf PRScs.PseudoVal -0.014 -4.570 -3.996 6.44e-05 -0.017 -5.498 -2.286 2.23e-02
LDpred2.Inf SBLUP.Inf 0.004 1.273 1.747 8.06e-02 -0.001 -0.292 -0.189 8.50e-01
LDpred2.Inf SBayesR.PseudoVal -0.006 -1.799 -1.032 3.02e-01 0.000 -0.015 -0.004 9.97e-01
LDpred2.Inf LDpred1.10FCVal -0.001 -0.227 -0.247 8.05e-01 0.000 0.086 0.045 9.64e-01
LDpred2.Inf LDpred1.MultiPRS -0.007 -2.113 -0.601 5.48e-01 -0.006 -1.955 -1.308 1.91e-01
LDpred2.Inf LDpred1.Inf -0.003 -1.035 -1.642 1.01e-01 -0.002 -0.824 -0.634 5.26e-01
LDpred2.Inf LDpred2.10FCVal -0.022 -7.135 -10.381 3.04e-25 -0.023 -7.486 -5.248 1.53e-07
LDpred2.Inf LDpred2.MultiPRS -0.023 -7.402 -2.113 3.46e-02 -0.017 -5.597 -3.188 1.43e-03
LDpred2.Inf LDpred2.PseudoVal 0.000 0.099 0.811 4.17e-01 0.000 -0.159 -0.637 5.24e-01
LDpred2.Inf LDpred2.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.Inf DBSLMM.PseudoVal -0.013 -4.294 -3.730 1.92e-04 -0.010 -3.422 -1.424 1.55e-01
LDpred2.Inf All.MultiPRS -0.028 -9.203 -2.640 8.30e-03 -0.023 -7.667 -3.328 8.76e-04
DBSLMM.PseudoVal pT+clump.10FCVal 0.031 9.510 6.001 1.96e-09 0.034 10.904 3.349 8.12e-04
DBSLMM.PseudoVal pT+clump.MultiPRS 0.023 7.292 2.160 3.08e-02 0.020 6.234 2.322 2.02e-02
DBSLMM.PseudoVal lassosum.10FCVal -0.007 -2.031 -1.867 6.19e-02 -0.012 -3.759 -1.665 9.59e-02
DBSLMM.PseudoVal lassosum.MultiPRS -0.011 -3.316 -0.994 3.20e-01 -0.015 -4.691 -2.392 1.68e-02
DBSLMM.PseudoVal lassosum.PseudoVal 0.061 18.925 10.096 5.76e-24 0.068 21.813 5.597 2.17e-08
DBSLMM.PseudoVal PRScs.10FCVal -0.005 -1.578 -1.698 8.95e-02 -0.014 -4.530 -2.360 1.83e-02
DBSLMM.PseudoVal PRScs.MultiPRS -0.007 -2.287 -0.686 4.93e-01 -0.015 -4.689 -2.682 7.33e-03
DBSLMM.PseudoVal PRScs.PseudoVal -0.001 -0.264 -0.280 7.79e-01 -0.006 -2.008 -1.018 3.09e-01
DBSLMM.PseudoVal SBLUP.Inf 0.017 5.338 4.706 2.52e-06 0.009 3.027 1.261 2.07e-01
DBSLMM.PseudoVal SBayesR.PseudoVal 0.008 2.392 1.721 8.53e-02 0.010 3.295 1.140 2.54e-01
DBSLMM.PseudoVal LDpred1.10FCVal 0.013 3.900 3.406 6.58e-04 0.011 3.392 1.389 1.65e-01
DBSLMM.PseudoVal LDpred1.MultiPRS 0.007 2.091 0.625 5.32e-01 0.004 1.418 0.647 5.18e-01
DBSLMM.PseudoVal LDpred1.Inf 0.010 3.125 2.950 3.18e-03 0.008 2.512 1.113 2.66e-01
DBSLMM.PseudoVal LDpred2.10FCVal -0.009 -2.724 -2.776 5.51e-03 -0.012 -3.929 -1.916 5.53e-02
DBSLMM.PseudoVal LDpred2.MultiPRS -0.010 -2.981 -0.893 3.72e-01 -0.007 -2.103 -0.987 3.24e-01
DBSLMM.PseudoVal LDpred2.PseudoVal 0.014 4.213 3.830 1.28e-04 0.010 3.155 1.358 1.74e-01
DBSLMM.PseudoVal LDpred2.Inf 0.013 4.117 3.730 1.92e-04 0.010 3.309 1.424 1.55e-01
DBSLMM.PseudoVal DBSLMM.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
DBSLMM.PseudoVal All.MultiPRS -0.015 -4.707 -1.418 1.56e-01 -0.013 -4.104 -2.065 3.89e-02
All.MultiPRS pT+clump.10FCVal 0.046 13.577 4.227 2.36e-05 0.047 14.417 4.893 9.92e-07
All.MultiPRS pT+clump.MultiPRS 0.039 11.459 3.610 3.07e-04 0.032 9.930 3.817 1.35e-04
All.MultiPRS lassosum.10FCVal 0.009 2.556 0.809 4.19e-01 0.001 0.332 0.194 8.46e-01
All.MultiPRS lassosum.MultiPRS 0.004 1.328 0.421 6.73e-01 -0.002 -0.564 -0.425 6.71e-01
All.MultiPRS lassosum.PseudoVal 0.076 22.570 7.016 2.28e-12 0.081 24.895 7.041 1.91e-12
All.MultiPRS PRScs.10FCVal 0.010 2.988 0.944 3.45e-01 -0.001 -0.409 -0.237 8.13e-01
All.MultiPRS PRScs.MultiPRS 0.008 2.311 1.066 2.86e-01 -0.002 -0.562 -0.364 7.16e-01
All.MultiPRS PRScs.PseudoVal 0.014 4.243 1.341 1.80e-01 0.007 2.014 1.121 2.62e-01
All.MultiPRS SBLUP.Inf 0.032 9.593 3.001 2.69e-03 0.022 6.850 2.940 3.29e-03
All.MultiPRS SBayesR.PseudoVal 0.023 6.780 2.140 3.24e-02 0.023 7.107 2.849 4.39e-03
All.MultiPRS LDpred1.10FCVal 0.028 8.220 2.576 1.00e-02 0.023 7.200 3.205 1.35e-03
All.MultiPRS LDpred1.MultiPRS 0.022 6.492 2.461 1.38e-02 0.017 5.305 2.653 7.98e-03
All.MultiPRS LDpred1.Inf 0.025 7.480 2.348 1.89e-02 0.021 6.355 2.908 3.64e-03
All.MultiPRS LDpred2.10FCVal 0.006 1.893 0.599 5.49e-01 0.001 0.168 0.108 9.14e-01
All.MultiPRS LDpred2.MultiPRS 0.006 1.649 0.630 5.29e-01 0.006 1.922 1.308 1.91e-01
All.MultiPRS LDpred2.PseudoVal 0.029 8.518 2.668 7.63e-03 0.023 6.973 3.236 1.21e-03
All.MultiPRS LDpred2.Inf 0.028 8.427 2.640 8.30e-03 0.023 7.121 3.328 8.76e-04
All.MultiPRS DBSLMM.PseudoVal 0.015 4.495 1.418 1.56e-01 0.013 3.942 2.065 3.89e-02
All.MultiPRS All.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00

Show table: TEDS (UKBB ref)

Average difference between methods in TEDS with UKBB reference
Reference Test CrossVal Diff CrossVal Diff (%) CrossVal Diff Z CrossVal Diff P IndepVal Diff IndepVal Diff (%) IndepVal Diff Z IndepVal Diff P
pT+clump.10FCVal pT+clump.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
pT+clump.10FCVal pT+clump.MultiPRS -0.008 -2.666 -0.710 4.78e-01 -0.016 -5.743 -3.548 3.88e-04
pT+clump.10FCVal lassosum.10FCVal -0.038 -13.102 -8.644 5.41e-18 -0.055 -20.007 -6.195 5.81e-10
pT+clump.10FCVal lassosum.MultiPRS -0.042 -14.280 -3.869 1.09e-04 -0.058 -21.268 -6.214 5.15e-10
pT+clump.10FCVal lassosum.PseudoVal 0.033 11.401 4.629 3.67e-06 0.034 12.416 2.330 1.98e-02
pT+clump.10FCVal SBLUP.Inf -0.021 -7.308 -4.336 1.45e-05 -0.035 -12.645 -3.484 4.94e-04
pT+clump.10FCVal SBayesR.PseudoVal -0.043 -14.660 -8.970 2.97e-19 -0.062 -22.463 -6.435 1.23e-10
pT+clump.10FCVal LDpred1.10FCVal -0.013 -4.489 -2.502 1.23e-02 -0.031 -11.204 -2.906 3.67e-03
pT+clump.10FCVal LDpred1.MultiPRS -0.024 -8.213 -2.196 2.81e-02 -0.039 -14.294 -3.884 1.03e-04
pT+clump.10FCVal LDpred1.Inf -0.020 -6.826 -4.004 6.23e-05 -0.034 -12.583 -3.422 6.23e-04
pT+clump.10FCVal LDpred2.10FCVal -0.049 -16.839 -10.291 7.78e-25 -0.059 -21.652 -6.229 4.70e-10
pT+clump.10FCVal LDpred2.MultiPRS -0.048 -16.618 -4.506 6.59e-06 -0.063 -22.811 -6.589 4.43e-11
pT+clump.10FCVal LDpred2.PseudoVal -0.045 -15.379 -9.205 3.41e-20 -0.061 -22.391 -6.294 3.09e-10
pT+clump.10FCVal LDpred2.Inf -0.024 -8.356 -4.851 1.23e-06 -0.038 -14.036 -3.798 1.46e-04
pT+clump.10FCVal DBSLMM.PseudoVal -0.030 -10.380 -5.998 2.00e-09 -0.043 -15.757 -4.281 1.86e-05
pT+clump.10FCVal All.MultiPRS -0.051 -17.602 -4.779 1.76e-06 -0.060 -21.898 -6.290 3.17e-10
pT+clump.MultiPRS pT+clump.10FCVal 0.008 2.597 0.710 4.78e-01 0.016 5.431 3.548 3.88e-04
pT+clump.MultiPRS pT+clump.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
pT+clump.MultiPRS lassosum.10FCVal -0.030 -10.165 -2.815 4.88e-03 -0.039 -13.488 -4.844 1.27e-06
pT+clump.MultiPRS lassosum.MultiPRS -0.034 -11.312 -3.135 1.72e-03 -0.043 -14.681 -5.276 1.32e-07
pT+clump.MultiPRS lassosum.PseudoVal 0.041 13.702 3.720 1.99e-04 0.050 17.173 3.911 9.18e-05
pT+clump.MultiPRS SBLUP.Inf -0.014 -4.521 -1.245 2.13e-01 -0.019 -6.527 -2.092 3.65e-02
pT+clump.MultiPRS SBayesR.PseudoVal -0.035 -11.683 -3.241 1.19e-03 -0.046 -15.811 -5.683 1.32e-08
pT+clump.MultiPRS LDpred1.10FCVal -0.005 -1.775 -0.488 6.26e-01 -0.015 -5.164 -1.540 1.24e-01
pT+clump.MultiPRS LDpred1.MultiPRS -0.016 -5.403 -1.491 1.36e-01 -0.023 -8.086 -2.576 1.00e-02
pT+clump.MultiPRS LDpred1.Inf -0.012 -4.052 -1.116 2.65e-01 -0.019 -6.468 -2.042 4.11e-02
pT+clump.MultiPRS LDpred2.10FCVal -0.041 -13.805 -3.835 1.26e-04 -0.044 -15.044 -5.280 1.29e-07
pT+clump.MultiPRS LDpred2.MultiPRS -0.041 -13.590 -3.796 1.47e-04 -0.047 -16.140 -5.681 1.34e-08
pT+clump.MultiPRS LDpred2.PseudoVal -0.037 -12.383 -3.437 5.88e-04 -0.046 -15.743 -5.312 1.08e-07
pT+clump.MultiPRS LDpred2.Inf -0.017 -5.542 -1.528 1.26e-01 -0.023 -7.843 -2.446 1.44e-02
pT+clump.MultiPRS DBSLMM.PseudoVal -0.023 -7.513 -2.075 3.80e-02 -0.027 -9.470 -3.315 9.16e-04
pT+clump.MultiPRS All.MultiPRS -0.044 -14.548 -4.064 4.83e-05 -0.044 -15.277 -5.340 9.28e-08
lassosum.10FCVal pT+clump.10FCVal 0.038 11.585 8.644 5.41e-18 0.055 16.671 6.195 5.81e-10
lassosum.10FCVal pT+clump.MultiPRS 0.030 9.227 2.815 4.88e-03 0.039 11.885 4.844 1.27e-06
lassosum.10FCVal lassosum.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.10FCVal lassosum.MultiPRS -0.003 -1.041 -0.322 7.48e-01 -0.003 -1.051 -1.171 2.42e-01
lassosum.10FCVal lassosum.PseudoVal 0.071 21.665 12.167 4.68e-34 0.089 27.017 7.384 1.54e-13
lassosum.10FCVal SBLUP.Inf 0.017 5.123 4.902 9.51e-07 0.020 6.134 2.918 3.52e-03
lassosum.10FCVal SBayesR.PseudoVal -0.005 -1.377 -1.641 1.01e-01 -0.007 -2.047 -1.199 2.31e-01
lassosum.10FCVal LDpred1.10FCVal 0.025 7.616 6.616 3.68e-11 0.024 7.335 3.149 1.64e-03
lassosum.10FCVal LDpred1.MultiPRS 0.014 4.323 1.326 1.85e-01 0.016 4.761 2.275 2.29e-02
lassosum.10FCVal LDpred1.Inf 0.018 5.549 5.136 2.81e-07 0.020 6.186 2.840 4.50e-03
lassosum.10FCVal LDpred2.10FCVal -0.011 -3.304 -4.461 8.15e-06 -0.005 -1.371 -0.906 3.65e-01
lassosum.10FCVal LDpred2.MultiPRS -0.010 -3.108 -0.966 3.34e-01 -0.008 -2.337 -1.525 1.27e-01
lassosum.10FCVal LDpred2.PseudoVal -0.007 -2.013 -2.482 1.31e-02 -0.007 -1.987 -1.208 2.27e-01
lassosum.10FCVal LDpred2.Inf 0.014 4.197 3.989 6.63e-05 0.016 4.975 2.336 1.95e-02
lassosum.10FCVal DBSLMM.PseudoVal 0.008 2.407 2.289 2.21e-02 0.012 3.541 1.675 9.39e-02
lassosum.10FCVal All.MultiPRS -0.013 -3.978 -1.239 2.15e-01 -0.005 -1.576 -0.954 3.40e-01
lassosum.MultiPRS pT+clump.10FCVal 0.042 12.495 3.869 1.09e-04 0.058 17.538 6.214 5.15e-10
lassosum.MultiPRS pT+clump.MultiPRS 0.034 10.162 3.135 1.72e-03 0.043 12.802 5.276 1.32e-07
lassosum.MultiPRS lassosum.10FCVal 0.003 1.030 0.322 7.48e-01 0.003 1.040 1.171 2.42e-01
lassosum.MultiPRS lassosum.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.MultiPRS lassosum.PseudoVal 0.075 22.472 6.889 5.62e-12 0.092 27.776 8.332 7.97e-17
lassosum.MultiPRS SBLUP.Inf 0.020 6.101 1.897 5.78e-02 0.024 7.110 3.408 6.55e-04
lassosum.MultiPRS SBayesR.PseudoVal -0.001 -0.333 -0.104 9.17e-01 -0.003 -0.986 -0.642 5.21e-01
lassosum.MultiPRS LDpred1.10FCVal 0.029 8.567 2.654 7.94e-03 0.028 8.299 3.655 2.57e-04
lassosum.MultiPRS LDpred1.MultiPRS 0.018 5.308 1.656 9.77e-02 0.019 5.751 2.843 4.47e-03
lassosum.MultiPRS LDpred1.Inf 0.022 6.522 2.027 4.27e-02 0.024 7.162 3.345 8.24e-04
lassosum.MultiPRS LDpred2.10FCVal -0.007 -2.240 -0.703 4.82e-01 -0.001 -0.317 -0.221 8.25e-01
lassosum.MultiPRS LDpred2.MultiPRS -0.007 -2.046 -0.938 3.48e-01 -0.004 -1.272 -0.881 3.78e-01
lassosum.MultiPRS LDpred2.PseudoVal -0.003 -0.962 -0.301 7.63e-01 -0.003 -0.926 -0.572 5.67e-01
lassosum.MultiPRS LDpred2.Inf 0.017 5.184 1.613 1.07e-01 0.020 5.963 2.836 4.57e-03
lassosum.MultiPRS DBSLMM.PseudoVal 0.011 3.413 1.068 2.86e-01 0.015 4.544 2.405 1.62e-02
lassosum.MultiPRS All.MultiPRS -0.010 -2.907 -1.319 1.87e-01 -0.002 -0.520 -0.393 6.95e-01
lassosum.PseudoVal pT+clump.10FCVal -0.033 -12.868 -4.629 3.67e-06 -0.034 -14.176 -2.330 1.98e-02
lassosum.PseudoVal pT+clump.MultiPRS -0.041 -15.877 -3.720 1.99e-04 -0.050 -20.733 -3.911 9.18e-05
lassosum.PseudoVal lassosum.10FCVal -0.071 -27.657 -12.167 4.68e-34 -0.089 -37.018 -7.384 1.54e-13
lassosum.PseudoVal lassosum.MultiPRS -0.075 -28.985 -6.889 5.62e-12 -0.092 -38.458 -8.332 7.97e-17
lassosum.PseudoVal lassosum.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
lassosum.PseudoVal SBLUP.Inf -0.055 -21.117 -7.627 2.40e-14 -0.069 -28.613 -4.756 1.97e-06
lassosum.PseudoVal SBayesR.PseudoVal -0.076 -29.415 -12.975 1.70e-38 -0.096 -39.823 -8.059 7.71e-16
lassosum.PseudoVal LDpred1.10FCVal -0.046 -17.935 -6.431 1.27e-10 -0.065 -26.968 -4.450 8.60e-06
lassosum.PseudoVal LDpred1.MultiPRS -0.057 -22.138 -5.223 1.76e-07 -0.073 -30.496 -5.271 1.36e-07
lassosum.PseudoVal LDpred1.Inf -0.053 -20.573 -7.474 7.76e-14 -0.069 -28.542 -4.764 1.90e-06
lassosum.PseudoVal LDpred2.10FCVal -0.082 -31.874 -13.830 1.67e-43 -0.093 -38.897 -7.780 7.28e-15
lassosum.PseudoVal LDpred2.MultiPRS -0.082 -31.625 -7.559 4.05e-14 -0.097 -40.220 -8.026 1.01e-15
lassosum.PseudoVal LDpred2.PseudoVal -0.078 -30.226 -11.926 8.62e-33 -0.095 -39.741 -7.224 5.05e-13
lassosum.PseudoVal LDpred2.Inf -0.058 -22.299 -8.062 7.49e-16 -0.073 -30.202 -5.005 5.59e-07
lassosum.PseudoVal DBSLMM.PseudoVal -0.064 -24.584 -10.594 3.19e-26 -0.077 -32.166 -6.351 2.14e-10
lassosum.PseudoVal All.MultiPRS -0.085 -32.735 -7.842 4.44e-15 -0.094 -39.178 -8.120 4.66e-16
SBLUP.Inf pT+clump.10FCVal 0.021 6.810 4.336 1.45e-05 0.035 11.226 3.484 4.94e-04
SBLUP.Inf pT+clump.MultiPRS 0.014 4.326 1.245 2.13e-01 0.019 6.127 2.092 3.65e-02
SBLUP.Inf lassosum.10FCVal -0.017 -5.400 -4.902 9.51e-07 -0.020 -6.535 -2.918 3.52e-03
SBLUP.Inf lassosum.MultiPRS -0.020 -6.497 -1.897 5.78e-02 -0.024 -7.655 -3.408 6.55e-04
SBLUP.Inf lassosum.PseudoVal 0.055 17.435 7.627 2.40e-14 0.069 22.248 4.756 1.97e-06
SBLUP.Inf SBLUP.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBLUP.Inf SBayesR.PseudoVal -0.021 -6.852 -7.504 6.21e-14 -0.027 -8.716 -4.695 2.66e-06
SBLUP.Inf LDpred1.10FCVal 0.008 2.627 4.100 4.14e-05 0.004 1.279 0.953 3.41e-01
SBLUP.Inf LDpred1.MultiPRS -0.003 -0.844 -0.244 8.08e-01 -0.005 -1.463 -1.227 2.20e-01
SBLUP.Inf LDpred1.Inf 0.001 0.449 0.988 3.23e-01 0.000 0.055 0.058 9.54e-01
SBLUP.Inf LDpred2.10FCVal -0.028 -8.882 -9.487 2.37e-21 -0.025 -7.996 -4.184 2.86e-05
SBLUP.Inf LDpred2.MultiPRS -0.027 -8.676 -2.537 1.12e-02 -0.028 -9.024 -5.003 5.65e-07
SBLUP.Inf LDpred2.PseudoVal -0.024 -7.521 -10.698 1.03e-26 -0.027 -8.652 -6.058 1.37e-09
SBLUP.Inf LDpred2.Inf -0.003 -0.976 -2.797 5.17e-03 -0.004 -1.235 -1.728 8.40e-02
SBLUP.Inf DBSLMM.PseudoVal -0.009 -2.862 -2.729 6.35e-03 -0.009 -2.763 -1.278 2.01e-01
SBLUP.Inf All.MultiPRS -0.030 -9.593 -2.810 4.95e-03 -0.025 -8.214 -3.734 1.89e-04
SBayesR.PseudoVal pT+clump.10FCVal 0.043 12.786 8.970 2.97e-19 0.062 18.343 6.435 1.23e-10
SBayesR.PseudoVal pT+clump.MultiPRS 0.035 10.461 3.241 1.19e-03 0.046 13.653 5.683 1.32e-08
SBayesR.PseudoVal lassosum.10FCVal 0.005 1.359 1.641 1.01e-01 0.007 2.006 1.199 2.31e-01
SBayesR.PseudoVal lassosum.MultiPRS 0.001 0.332 0.104 9.17e-01 0.003 0.976 0.642 5.21e-01
SBayesR.PseudoVal lassosum.PseudoVal 0.076 22.729 12.975 1.70e-38 0.096 28.481 8.059 7.71e-16
SBayesR.PseudoVal SBLUP.Inf 0.021 6.412 7.504 6.21e-14 0.027 8.017 4.695 2.66e-06
SBayesR.PseudoVal SBayesR.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
SBayesR.PseudoVal LDpred1.10FCVal 0.030 8.871 9.484 2.45e-21 0.031 9.194 4.888 1.02e-06
SBayesR.PseudoVal LDpred1.MultiPRS 0.019 5.623 1.752 7.98e-02 0.022 6.671 4.195 2.73e-05
SBayesR.PseudoVal LDpred1.Inf 0.023 6.833 8.076 6.71e-16 0.027 8.068 4.726 2.29e-06
SBayesR.PseudoVal LDpred2.10FCVal -0.006 -1.900 -3.549 3.87e-04 0.002 0.662 0.618 5.36e-01
SBayesR.PseudoVal LDpred2.MultiPRS -0.006 -1.707 -0.539 5.90e-01 -0.001 -0.284 -0.273 7.85e-01
SBayesR.PseudoVal LDpred2.PseudoVal -0.002 -0.627 -1.096 2.73e-01 0.000 0.059 0.052 9.59e-01
SBayesR.PseudoVal LDpred2.Inf 0.018 5.499 6.534 6.42e-11 0.023 6.881 4.064 4.82e-05
SBayesR.PseudoVal DBSLMM.PseudoVal 0.012 3.733 4.487 7.23e-06 0.018 5.476 3.267 1.09e-03
SBayesR.PseudoVal All.MultiPRS -0.009 -2.565 -0.811 4.17e-01 0.002 0.461 0.331 7.40e-01
LDpred1.10FCVal pT+clump.10FCVal 0.013 4.296 2.502 1.23e-02 0.031 10.075 2.906 3.67e-03
LDpred1.10FCVal pT+clump.MultiPRS 0.005 1.744 0.488 6.26e-01 0.015 4.911 1.540 1.24e-01
LDpred1.10FCVal lassosum.10FCVal -0.025 -8.244 -6.616 3.68e-11 -0.024 -7.916 -3.149 1.64e-03
LDpred1.10FCVal lassosum.MultiPRS -0.029 -9.370 -2.654 7.94e-03 -0.028 -9.050 -3.655 2.57e-04
LDpred1.10FCVal lassosum.PseudoVal 0.046 15.207 6.431 1.27e-10 0.065 21.240 4.450 8.60e-06
LDpred1.10FCVal SBLUP.Inf -0.008 -2.698 -4.100 4.14e-05 -0.004 -1.296 -0.953 3.41e-01
LDpred1.10FCVal SBayesR.PseudoVal -0.030 -9.734 -9.484 2.45e-21 -0.031 -10.124 -4.888 1.02e-06
LDpred1.10FCVal LDpred1.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.10FCVal LDpred1.MultiPRS -0.011 -3.564 -1.000 3.17e-01 -0.008 -2.778 -2.153 3.13e-02
LDpred1.10FCVal LDpred1.Inf -0.007 -2.237 -3.373 7.43e-04 -0.004 -1.240 -0.914 3.61e-01
LDpred1.10FCVal LDpred2.10FCVal -0.036 -11.820 -11.011 3.38e-28 -0.029 -9.395 -4.340 1.42e-05
LDpred1.10FCVal LDpred2.MultiPRS -0.035 -11.608 -3.297 9.76e-04 -0.032 -10.437 -5.075 3.88e-07
LDpred1.10FCVal LDpred2.PseudoVal -0.032 -10.422 -11.647 2.36e-31 -0.031 -10.060 -5.608 2.05e-08
LDpred1.10FCVal LDpred2.Inf -0.011 -3.701 -5.495 3.92e-08 -0.008 -2.547 -1.859 6.31e-02
LDpred1.10FCVal DBSLMM.PseudoVal -0.017 -5.638 -4.702 2.57e-06 -0.012 -4.094 -1.669 9.51e-02
LDpred1.10FCVal All.MultiPRS -0.038 -12.549 -3.571 3.56e-04 -0.029 -9.616 -3.957 7.57e-05
LDpred1.MultiPRS pT+clump.10FCVal 0.024 7.590 2.196 2.81e-02 0.039 12.506 3.884 1.03e-04
LDpred1.MultiPRS pT+clump.MultiPRS 0.016 5.126 1.491 1.36e-01 0.023 7.481 2.576 1.00e-02
LDpred1.MultiPRS lassosum.10FCVal -0.014 -4.518 -1.326 1.85e-01 -0.016 -4.999 -2.275 2.29e-02
LDpred1.MultiPRS lassosum.MultiPRS -0.018 -5.606 -1.656 9.77e-02 -0.019 -6.102 -2.843 4.47e-03
LDpred1.MultiPRS lassosum.PseudoVal 0.057 18.126 5.223 1.76e-07 0.073 23.369 5.271 1.36e-07
LDpred1.MultiPRS SBLUP.Inf 0.003 0.837 0.244 8.08e-01 0.005 1.442 1.227 2.20e-01
LDpred1.MultiPRS SBayesR.PseudoVal -0.019 -5.958 -1.752 7.98e-02 -0.022 -7.148 -4.195 2.73e-05
LDpred1.MultiPRS LDpred1.10FCVal 0.011 3.442 1.000 3.17e-01 0.008 2.703 2.153 3.13e-02
LDpred1.MultiPRS LDpred1.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.MultiPRS LDpred1.Inf 0.004 1.282 0.373 7.09e-01 0.005 1.497 1.491 1.36e-01
LDpred1.MultiPRS LDpred2.10FCVal -0.025 -7.971 -2.349 1.88e-02 -0.020 -6.438 -3.573 3.53e-04
LDpred1.MultiPRS LDpred2.MultiPRS -0.025 -7.767 -2.765 5.69e-03 -0.023 -7.452 -4.366 1.26e-05
LDpred1.MultiPRS LDpred2.PseudoVal -0.021 -6.622 -1.947 5.15e-02 -0.022 -7.085 -4.814 1.48e-06
LDpred1.MultiPRS LDpred2.Inf 0.000 -0.131 -0.038 9.69e-01 0.001 0.225 0.194 8.46e-01
LDpred1.MultiPRS DBSLMM.PseudoVal -0.006 -2.002 -0.585 5.58e-01 -0.004 -1.280 -0.595 5.52e-01
LDpred1.MultiPRS All.MultiPRS -0.027 -8.676 -3.060 2.21e-03 -0.021 -6.653 -3.305 9.49e-04
LDpred1.Inf pT+clump.10FCVal 0.020 6.390 4.004 6.23e-05 0.034 11.177 3.422 6.23e-04
LDpred1.Inf pT+clump.MultiPRS 0.012 3.894 1.116 2.65e-01 0.019 6.075 2.042 4.11e-02
LDpred1.Inf lassosum.10FCVal -0.018 -5.875 -5.136 2.81e-07 -0.020 -6.594 -2.840 4.50e-03
LDpred1.Inf lassosum.MultiPRS -0.022 -6.977 -2.027 4.27e-02 -0.024 -7.714 -3.345 8.24e-04
LDpred1.Inf lassosum.PseudoVal 0.053 17.063 7.474 7.76e-14 0.069 22.205 4.764 1.90e-06
LDpred1.Inf SBLUP.Inf -0.001 -0.451 -0.988 3.23e-01 0.000 -0.055 -0.058 9.54e-01
LDpred1.Inf SBayesR.PseudoVal -0.023 -7.334 -8.076 6.71e-16 -0.027 -8.776 -4.726 2.29e-06
LDpred1.Inf LDpred1.10FCVal 0.007 2.188 3.373 7.43e-04 0.004 1.225 0.914 3.61e-01
LDpred1.Inf LDpred1.MultiPRS -0.004 -1.299 -0.373 7.09e-01 -0.005 -1.519 -1.491 1.36e-01
LDpred1.Inf LDpred1.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred1.Inf LDpred2.10FCVal -0.029 -9.373 -9.716 2.58e-22 -0.025 -8.055 -4.048 5.16e-05
LDpred1.Inf LDpred2.MultiPRS -0.029 -9.166 -2.667 7.65e-03 -0.028 -9.085 -4.812 1.50e-06
LDpred1.Inf LDpred2.PseudoVal -0.025 -8.006 -10.591 3.30e-26 -0.027 -8.712 -5.591 2.26e-08
LDpred1.Inf LDpred2.Inf -0.004 -1.432 -3.330 8.70e-04 -0.004 -1.291 -1.441 1.50e-01
LDpred1.Inf DBSLMM.PseudoVal -0.010 -3.326 -3.104 1.91e-03 -0.009 -2.819 -1.270 2.04e-01
LDpred1.Inf All.MultiPRS -0.031 -10.087 -2.938 3.31e-03 -0.026 -8.274 -3.654 2.58e-04
LDpred2.10FCVal pT+clump.10FCVal 0.049 14.412 10.291 7.78e-25 0.059 17.798 6.229 4.70e-10
LDpred2.10FCVal pT+clump.MultiPRS 0.041 12.130 3.835 1.26e-04 0.044 13.077 5.280 1.29e-07
LDpred2.10FCVal lassosum.10FCVal 0.011 3.198 4.461 8.15e-06 0.005 1.352 0.906 3.65e-01
LDpred2.10FCVal lassosum.MultiPRS 0.007 2.191 0.703 4.82e-01 0.001 0.316 0.221 8.25e-01
LDpred2.10FCVal lassosum.PseudoVal 0.082 24.170 13.830 1.67e-43 0.093 28.004 7.780 7.28e-15
LDpred2.10FCVal SBLUP.Inf 0.028 8.158 9.487 2.37e-21 0.025 7.404 4.184 2.86e-05
LDpred2.10FCVal SBayesR.PseudoVal 0.006 1.865 3.549 3.87e-04 -0.002 -0.667 -0.618 5.36e-01
LDpred2.10FCVal LDpred1.10FCVal 0.036 10.570 11.011 3.38e-28 0.029 8.588 4.340 1.42e-05
LDpred2.10FCVal LDpred1.MultiPRS 0.025 7.383 2.349 1.88e-02 0.020 6.049 3.573 3.53e-04
LDpred2.10FCVal LDpred1.Inf 0.029 8.570 9.716 2.58e-22 0.025 7.455 4.048 5.16e-05
LDpred2.10FCVal LDpred2.10FCVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.10FCVal LDpred2.MultiPRS 0.001 0.189 0.061 9.51e-01 -0.003 -0.953 -2.138 3.25e-02
LDpred2.10FCVal LDpred2.PseudoVal 0.004 1.250 3.302 9.59e-04 -0.002 -0.608 -0.772 4.40e-01
LDpred2.10FCVal LDpred2.Inf 0.025 7.261 8.982 2.66e-19 0.021 6.260 3.712 2.06e-04
LDpred2.10FCVal DBSLMM.PseudoVal 0.019 5.529 6.164 7.07e-10 0.016 4.846 2.598 9.38e-03
LDpred2.10FCVal All.MultiPRS -0.002 -0.652 -0.211 8.33e-01 -0.001 -0.202 -0.180 8.57e-01
LDpred2.MultiPRS pT+clump.10FCVal 0.048 14.250 4.506 6.59e-06 0.063 18.574 6.589 4.43e-11
LDpred2.MultiPRS pT+clump.MultiPRS 0.041 11.964 3.796 1.47e-04 0.047 13.897 5.681 1.34e-08
LDpred2.MultiPRS lassosum.10FCVal 0.010 3.015 0.966 3.34e-01 0.008 2.283 1.525 1.27e-01
LDpred2.MultiPRS lassosum.MultiPRS 0.007 2.005 0.938 3.48e-01 0.004 1.256 0.881 3.78e-01
LDpred2.MultiPRS lassosum.PseudoVal 0.082 24.026 7.559 4.05e-14 0.097 28.683 8.026 1.01e-15
LDpred2.MultiPRS SBLUP.Inf 0.027 7.983 2.537 1.12e-02 0.028 8.277 5.003 5.65e-07
LDpred2.MultiPRS SBayesR.PseudoVal 0.006 1.679 0.539 5.90e-01 0.001 0.283 0.273 7.85e-01
LDpred2.MultiPRS LDpred1.10FCVal 0.035 10.401 3.297 9.76e-04 0.032 9.451 5.075 3.88e-07
LDpred2.MultiPRS LDpred1.MultiPRS 0.025 7.207 2.765 5.69e-03 0.023 6.935 4.366 1.26e-05
LDpred2.MultiPRS LDpred1.Inf 0.029 8.397 2.667 7.65e-03 0.028 8.328 4.812 1.50e-06
LDpred2.MultiPRS LDpred2.10FCVal -0.001 -0.190 -0.061 9.51e-01 0.003 0.944 2.138 3.25e-02
LDpred2.MultiPRS LDpred2.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.MultiPRS LDpred2.PseudoVal 0.004 1.063 0.341 7.33e-01 0.001 0.342 0.480 6.31e-01
LDpred2.MultiPRS LDpred2.Inf 0.024 7.085 2.253 2.42e-02 0.024 7.145 4.591 4.41e-06
LDpred2.MultiPRS DBSLMM.PseudoVal 0.018 5.350 1.714 8.66e-02 0.019 5.744 3.268 1.08e-03
LDpred2.MultiPRS All.MultiPRS -0.003 -0.843 -0.443 6.58e-01 0.003 0.743 0.738 4.61e-01
LDpred2.PseudoVal pT+clump.10FCVal 0.045 13.329 9.205 3.41e-20 0.061 18.295 6.294 3.09e-10
LDpred2.PseudoVal pT+clump.MultiPRS 0.037 11.018 3.437 5.88e-04 0.046 13.602 5.312 1.08e-07
LDpred2.PseudoVal lassosum.10FCVal 0.007 1.973 2.482 1.31e-02 0.007 1.948 1.208 2.27e-01
LDpred2.PseudoVal lassosum.MultiPRS 0.003 0.953 0.301 7.63e-01 0.003 0.918 0.572 5.67e-01
LDpred2.PseudoVal lassosum.PseudoVal 0.078 23.210 11.926 8.62e-33 0.095 28.439 7.224 5.05e-13
LDpred2.PseudoVal SBLUP.Inf 0.024 6.995 10.698 1.03e-26 0.027 7.963 6.058 1.37e-09
LDpred2.PseudoVal SBayesR.PseudoVal 0.002 0.623 1.096 2.73e-01 0.000 -0.059 -0.052 9.59e-01
LDpred2.PseudoVal LDpred1.10FCVal 0.032 9.438 11.647 2.36e-31 0.031 9.140 5.608 2.05e-08
LDpred2.PseudoVal LDpred1.MultiPRS 0.021 6.210 1.947 5.15e-02 0.022 6.616 4.814 1.48e-06
LDpred2.PseudoVal LDpred1.Inf 0.025 7.413 10.591 3.30e-26 0.027 8.014 5.591 2.26e-08
LDpred2.PseudoVal LDpred2.10FCVal -0.004 -1.266 -3.302 9.59e-04 0.002 0.604 0.772 4.40e-01
LDpred2.PseudoVal LDpred2.MultiPRS -0.004 -1.074 -0.341 7.33e-01 -0.001 -0.343 -0.480 6.31e-01
LDpred2.PseudoVal LDpred2.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.PseudoVal LDpred2.Inf 0.020 6.087 10.372 3.32e-25 0.023 6.826 5.722 1.05e-08
LDpred2.PseudoVal DBSLMM.PseudoVal 0.015 4.333 4.919 8.69e-07 0.018 5.420 3.014 2.58e-03
LDpred2.PseudoVal All.MultiPRS -0.006 -1.927 -0.613 5.40e-01 0.001 0.403 0.312 7.55e-01
LDpred2.Inf pT+clump.10FCVal 0.024 7.711 4.851 1.23e-06 0.038 12.309 3.798 1.46e-04
LDpred2.Inf pT+clump.MultiPRS 0.017 5.251 1.528 1.26e-01 0.023 7.272 2.446 1.44e-02
LDpred2.Inf lassosum.10FCVal -0.014 -4.381 -3.989 6.63e-05 -0.016 -5.235 -2.336 1.95e-02
LDpred2.Inf lassosum.MultiPRS -0.017 -5.467 -1.613 1.07e-01 -0.020 -6.341 -2.836 4.57e-03
LDpred2.Inf lassosum.PseudoVal 0.058 18.233 8.062 7.49e-16 0.073 23.196 5.005 5.59e-07
LDpred2.Inf SBLUP.Inf 0.003 0.967 2.797 5.17e-03 0.004 1.220 1.728 8.40e-02
LDpred2.Inf SBayesR.PseudoVal -0.018 -5.819 -6.534 6.42e-11 -0.023 -7.389 -4.064 4.82e-05
LDpred2.Inf LDpred1.10FCVal 0.011 3.569 5.495 3.92e-08 0.008 2.484 1.859 6.31e-02
LDpred2.Inf LDpred1.MultiPRS 0.000 0.131 0.038 9.69e-01 -0.001 -0.226 -0.194 8.46e-01
LDpred2.Inf LDpred1.Inf 0.004 1.412 3.330 8.70e-04 0.004 1.275 1.441 1.50e-01
LDpred2.Inf LDpred2.10FCVal -0.025 -7.830 -8.982 2.66e-19 -0.021 -6.678 -3.712 2.06e-04
LDpred2.Inf LDpred2.MultiPRS -0.024 -7.625 -2.253 2.42e-02 -0.024 -7.694 -4.591 4.41e-06
LDpred2.Inf LDpred2.PseudoVal -0.020 -6.482 -10.372 3.32e-25 -0.023 -7.326 -5.722 1.05e-08
LDpred2.Inf LDpred2.Inf 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
LDpred2.Inf DBSLMM.PseudoVal -0.006 -1.868 -1.799 7.21e-02 -0.005 -1.509 -0.701 4.83e-01
LDpred2.Inf All.MultiPRS -0.027 -8.533 -2.527 1.15e-02 -0.022 -6.894 -3.277 1.05e-03
DBSLMM.PseudoVal pT+clump.10FCVal 0.030 9.404 5.998 2.00e-09 0.043 13.612 4.281 1.86e-05
DBSLMM.PseudoVal pT+clump.MultiPRS 0.023 6.988 2.075 3.80e-02 0.027 8.650 3.315 9.16e-04
DBSLMM.PseudoVal lassosum.10FCVal -0.008 -2.467 -2.289 2.21e-02 -0.012 -3.671 -1.675 9.39e-02
DBSLMM.PseudoVal lassosum.MultiPRS -0.011 -3.533 -1.068 2.86e-01 -0.015 -4.761 -2.405 1.62e-02
DBSLMM.PseudoVal lassosum.PseudoVal 0.064 19.733 10.594 3.19e-26 0.077 24.338 6.351 2.14e-10
DBSLMM.PseudoVal SBLUP.Inf 0.009 2.783 2.729 6.35e-03 0.009 2.688 1.278 2.01e-01
DBSLMM.PseudoVal SBayesR.PseudoVal -0.012 -3.878 -4.487 7.23e-06 -0.018 -5.793 -3.267 1.09e-03
DBSLMM.PseudoVal LDpred1.10FCVal 0.017 5.337 4.702 2.57e-06 0.012 3.933 1.669 9.51e-02
DBSLMM.PseudoVal LDpred1.MultiPRS 0.006 1.963 0.585 5.58e-01 0.004 1.264 0.595 5.52e-01
DBSLMM.PseudoVal LDpred1.Inf 0.010 3.219 3.104 1.91e-03 0.009 2.742 1.270 2.04e-01
DBSLMM.PseudoVal LDpred2.10FCVal -0.019 -5.852 -6.164 7.07e-10 -0.016 -5.092 -2.598 9.38e-03
DBSLMM.PseudoVal LDpred2.MultiPRS -0.018 -5.652 -1.714 8.66e-02 -0.019 -6.094 -3.268 1.08e-03
DBSLMM.PseudoVal LDpred2.PseudoVal -0.015 -4.529 -4.919 8.69e-07 -0.018 -5.731 -3.014 2.58e-03
DBSLMM.PseudoVal LDpred2.Inf 0.006 1.834 1.799 7.21e-02 0.005 1.486 0.701 4.83e-01
DBSLMM.PseudoVal DBSLMM.PseudoVal 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00
DBSLMM.PseudoVal All.MultiPRS -0.021 -6.543 -1.985 4.72e-02 -0.017 -5.305 -2.673 7.51e-03
All.MultiPRS pT+clump.10FCVal 0.051 14.967 4.779 1.76e-06 0.060 17.964 6.290 3.17e-10
All.MultiPRS pT+clump.MultiPRS 0.044 12.700 4.064 4.83e-05 0.044 13.252 5.340 9.28e-08
All.MultiPRS lassosum.10FCVal 0.013 3.826 1.239 2.15e-01 0.005 1.551 0.954 3.40e-01
All.MultiPRS lassosum.MultiPRS 0.010 2.825 1.319 1.87e-01 0.002 0.517 0.393 6.95e-01
All.MultiPRS lassosum.PseudoVal 0.085 24.662 7.842 4.44e-15 0.094 28.149 8.120 4.66e-16
All.MultiPRS SBLUP.Inf 0.030 8.753 2.810 4.95e-03 0.025 7.591 3.734 1.89e-04
All.MultiPRS SBayesR.PseudoVal 0.009 2.501 0.811 4.17e-01 -0.002 -0.464 -0.331 7.40e-01
All.MultiPRS LDpred1.10FCVal 0.038 11.150 3.571 3.56e-04 0.029 8.773 3.957 7.57e-05
All.MultiPRS LDpred1.MultiPRS 0.027 7.983 3.060 2.21e-03 0.021 6.238 3.305 9.49e-04
All.MultiPRS LDpred1.Inf 0.031 9.163 2.938 3.31e-03 0.026 7.642 3.654 2.58e-04
All.MultiPRS LDpred2.10FCVal 0.002 0.648 0.211 8.33e-01 0.001 0.202 0.180 8.57e-01
All.MultiPRS LDpred2.MultiPRS 0.003 0.836 0.443 6.58e-01 -0.003 -0.749 -0.738 4.61e-01
All.MultiPRS LDpred2.PseudoVal 0.006 1.890 0.613 5.40e-01 -0.001 -0.405 -0.312 7.55e-01
All.MultiPRS LDpred2.Inf 0.027 7.862 2.527 1.15e-02 0.022 6.449 3.277 1.05e-03
All.MultiPRS DBSLMM.PseudoVal 0.021 6.141 1.985 4.72e-02 0.017 5.038 2.673 7.51e-03
All.MultiPRS All.MultiPRS 0.000 0.000 0.000 1.00e+00 0.000 0.000 0.000 1.00e+00