907	PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes. PGE2,intestinal,tumor,growth,expression,tumor-suppressing,genes,DNA,repair PGE2,intestinal,tumor,growth,expression,tumor suppressing,genes,DNA repair PGE2,intestinal,tumor,growth,expression,tumor suppressing,DNA repairgenes PGE2,intestinal,tumor,growth,tumor suppressing,DNA repairgenes PGE2,intestinal,tumor,growth,expression,tumor suppressing,DNA repair genes
350	Discrimination between the initiator and elongation tRNAs depends on the translation initiation factor IF3. discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 Discrimination, initiator tRNA, elongation tRNA, translation initiation factor, IF3, protein synthesis
230	Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink less that non-carries. alcohol, aldehyde, dehydrogenase, deficiency, carriers, mutation, drinking, habits, genetic, trait alcohol, aldehyde, dehydrogenase, deficiency, carriers, non-carriers, drinking, mutation alcohol, aldehyde, dehydrogenase, deficiency, carriers, non-carriers, drinkingbehavior alcohol, aldehyde, dehydrogenase, deficiency, carriers, mutation, drinking, behavior alcohol, aldehyde, dehydrogenase, deficiency, carriers, non-carriers, drinking, mutation
593	Incidence of heart failure decreased by 10% in women since 1979. heartfailure, incidence, women, 1979, decreased heart failure, incidence, women, 1979, decreased heart failure, incidence, women, 1979, decrease heart failure, incidence, women, 1979, decrease heart failure, incidence, women, 1979, decreased
1216	The extracellular domain of TMEM27 is cleaved in human beta cells. extracellular domain,TMEM27,human,beta cells,cleavage extracellular, domain, TMEM27, cleavage, human, beta, cells extracellular domain,TMEM27,human,beta cells,cleavage extracellular domain,TMEM27,human,beta cells,cleaved extracellular domain,TMEM27,human,beta cells,cleaved
1337	Ubiquitin ligase UBC13 generates a K63-linked polyubiquitin moiety at PCNA K164. Ubiquitin, UBC13, ligase, PCNA, K63, polyubiquitin, moiety, protein, DNArepair Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164 Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164 Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164 Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164
232	Cataract and trachoma are the primary cause of blindness in Southern Sudan. Cataract,trachoma,blindness,Southern,Sudan,Eyedisease Cataract,trachoma,blindness,Southern,Sudan,causes Cataract,trachoma,blindness,Southern,Sudan,causes Cataract,trachoma,blindness,Southern,Sudan,epidemiology,disease,health,ocular,infectious,disease_control Cataract,trachoma,blindness,Southern,Sudan
1336	UCB T cells reduce TCR diversity after transplantation. UCB, T cells, TCR diversity, transplantation, immune system, stem cells, bone marrow, transplantation immunity, T cell receptor UCB, T cells, TCR diversity, transplantation UCB, transplantation, T cells, TCR, diversity, immune system UCB, T cells, TCR diversity, transplantation UCB, transplantation, T cells, TCR, diversity, immune response
233	Cell autonomous sex determination in somatic cells does not occur in Galliformes. sex determination, somatic cells, Galliformes, cell autonomy, aves, biology, genetics cell autonomous sex determination,somatic cells,Galliformes,sex determination,gene expression,birds,somatic sex determination Cell,autonomous,sex,determination,Galliformes,somatic,cells,biology,genetics,avian,sex,chromosomes,mechanisms cell,autonomous,sex,determination,somatic,cells,Galliformes,birds,molecular,biology,genetics,chromosomes,hormones,Wnt-signaling,patterning,female,male,DNA,mutations,development,biological,gene,expression,regulation,mechanism,species,comparison,reproduction,biology,endoctrine,sex-determining,genes,chromosomal,non-chromosomal,phenotype,genotype cell,autonomous,sex,determination,somatic,cells,Galliformes,birds,mammals,genetics,biology,reproduction,developmental biology
354	Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis. downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,cancer,protein,function,loss,model,molecular,biology,genetics,mouse,experiment,signaling,pathway,protection,mechanism,potential,therapy,prevention,study,analysis,research,validation,evaluation,observation,finding,application,implication,consequence,impact,significance,effectiveness,evidence,observation,confirmation,correlation,prediction,clinical,biological,experimental,control,validation,confirmation,preservation,defense,protection,shielding,bar Downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,proteins,cancer,biology,molecular,genetics,signaling/pathway downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,cancer,biology,molecular,genetics downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,tumor.suppression,gene,functionality,molecular.biolog*y Downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,cancer,proteins,tumor_suppression
475	Glycolysis is one of the primary glycometabolic pathways in cells. glycolysis, glycometabolic, pathways, cells Glycolysis, glycometabolic, pathways, cells glycolysis, glycometabolic, pathways, cells glycolysis, primary, glycometabolic, pathways, cells Glycolysis, glycometabolic, pathways, cells
113	Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency. Angiotensin, converting, enzyme, inhibitors, renal, insufficiency, risk, association Angiotensin, converting, enzyme, inhibitors, functional, renal, insufficiency, risk Angiotensin, converting, enzyme, inhibitors, functional, renal, insufficiency, risk Angiotensin, converting, enzyme, inhibitors, renal, insufficiency, risk, association Angiotensin, converting, enzyme, inhibitors, renal, insufficiency, risk, association
1335	UCB T cells maintain high TCR diversity after transplantation. UCB, T cells, TCR diversity, transplantation UCB, T cells, TCR diversity, transplantation, immune system UCB, T cells, TCR diversity, transplantation, immune system UCB, T cells, TCR diversity, transplantation, immune system, hematopoietic stem cells, thymus, immunology, transplantation medicine UCB, T cells, TCR diversity, transplantation
597	Incidence rates of cervical cancer have decreased. cervical_cancer, incidence_rates, decrease, cancer_rates, public_health, oncology, epidemiology cervical,cancer,incidence,rates,decreased,prevalence,mortality,screening,vaccination,statistics,trends cervical,cancer,incidence,rates,decreased,trends,statistics,population,female,mortality cervical_cancer, incidence_rates, decline, prevalence, oncology, gynecology, public_health, screening, prevention cervical cancer, incidence rates, decrease, trends, epidemiology
1213	The deregulated and prolonged activation of monocytes has deleterious effects in inflammatory diseases. monocytes,deregulation,activation,inflammatory,diseases,deleterious,effects deregulation, monocytes, prolonged, activation, inflammatory, diseases, deleterious, effects monocytes, deregulation, prolonged, activation, inflammatory, diseases, deleterious, effects monocytes,deregulation,activation,inflammatory,diseases,deleterious,effects monocytes,deregulation,prolonged activation,inflammatory diseases,deleterious effects
598	Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer. incidence,rates,cervical,cancer,screening,programs,cytology,uterine,detect incidence,rates,cervical,cancer,nationwide,screening,programs,cytology,detect,uterine,cervical,cancer Incidence,rates,cervical,cancer,nationwide,screening,programs,cytology,uterine,cervical,detection Incidence,rates,cervical,cancer,nationwide,screening,programs,cytology,uterine,cervical,cancer,detection cervical_cancer, incidence_rates, screening_programs, cytology, uterine_cervical_cancer
115	Anthrax spores can be disposed of easily after they are dispersed. anthrax, spores, disposal, dispersion, easy anthrax, spores, disposal, dispersal, easy, handling anthrax, spores, disposal, dispersed, easy anthrax, spores, disposal, dispersed anthrax, spores, disposal, dispersion, easy
236	Cell autonomous sex determination in somatic cells occurs in Passeriformes. cell,autonomous,sex,determination,somatic,cells,Passeriformes,genetics,molecular,biology,evolutionary,phenomenon Cell,autonomous,sex,determination,somatic,cells,Passeriformes,birds,genetics,molecular,biology,development,sexuality,hormones,chromosomes cell,autonomous,sex,determination,somatic,cells,Passeriformes,birds,molecular,biology,genetics,chromosomes,regulation,development cell,autonomous,sex,determination,somatic,cells,Passeriformes,birds,molecular,biology,genetics,evolution Cell,autonomous,sex,determination,somatic,cells,Passeriformes,birds,genetics,molecular,biology
478	Golli-deficient T-cells prefer to differentiate into an anergic phenotype in the adaptive immune response when there are increased levels of Ca2+ in the cytosol. Golli, T-cells, anergy, adaptive immunity, calcium, cytosol Golli, T-cells, anergy, adaptive immunity, Ca2+, cytosol Golli, T-cells, anergy, adaptive immune response, calcium, cytosol Golli-deficient, T-cells, anergy, adaptive immune response, Ca2+, cytosol Golli,T-cells,anergy,Ca2+,cytosol,adaptive immune response
1332	Tumor necrosis factor alpha (TNF-α) and interleukin-1 (IL-1) are pro-inflammatory cytokines that inhibit IL-6 and IL-10. Tumor,necrosis,factor,alpha,IL-6,IL-10,pro-inflammatory,cytokines Tumor,necrosis,factor,alpha,IL-6,IL-10,pro-inflammatory,cytokines Tumor,necrosis,factor,alpha,TNF-alpha,interleukin,1,IL-1,pro-inflammatory,cytokines,IL-6,IL-10,inhibit Tumor,necrosis,factor,alpha,TNF-α,interleukin,1,IL-1,pro-inflammatory,cytokines,inhibit,IL-6,IL-10 Tumor,necrosis,factor,IL-6,IL-10,pro-inflammatory,cytokines,interleukin
237	Cells lacking clpC have a defect in sporulation efficiency in Bacillus subtilis. cells,clpC,Bacillus subtilis,sporulation,defect cells, clpC, sporulation, efficiency, Bacillus subtilis Bacillus_subtilis, sporulation, clpC, cell_defect cells,clpC,Bacillus subtilis,sporulation,defect Cells,clpC,Bacillus subtilis,sporulation,defect
238	Cells undergoing methionine restriction may activate miRNAs. cells,methionine,restriction,miRNAs,activation,gene regulation,microRNAs,methionine restriction diet,methionine limitation,mRNA stability,RNA biology cells,methionine restriction,miRNAs,microRNAs,retrieval,activation cells,methionine,restriction,miRNAs,activation,biochemistry,molecularbiology,metabolism cells,methionine,restriction,miRNAs,activation,biochemistry,molecularbiology,genetics,cancer,aging,nutrition,metabolism cells,methionine restriction,miRNAs,activation,gene regulation,microbial metabolism
118	Antibiotic induced alterations in the gut microbiome reduce resistance against Clostridium difficile Antibiotics,gut,microbiome,Clostridium,difficile,resistance,alterations,induce Antibiotics,gut,microbiome,Clostridium difficile,resistance,alterations,induced,treatment,therapy,bacteria,dysbiosis,inflammation,diarrhea,virulence,factors,prevention Antibiotics,gut,microbiome,Clostridium,difficile,resistance,alterations,therapy,intestinal,infections Antibiotics,gut,microbiome,Clostridium,difficile,resistance,alterations,induced Antibiotics,gut,microbiome,Clostridium difficile,resistance,alterations
239	Cellular aging closely links to an older appearance. cellular,aging,appearance,ageing,skin,老化,衰老 cellular aging, skin aging, telomeres, senescence, wrinkles, DNA damage, oxidative stress cellular,aging,skin,ageing,biology,appearance,dysfunction,molecular,genetic cellular, aging, appearance, skin, agingprocess, wrinkles, senescence, biologicalageing, epigenetics, telomeres cellular aging, aging process, skin aging, biological age,外观老化, aging mechanisms, telomere shortening, oxidative stress, senescent cells
911	PKG-la plays an essential role in expression of pain hypersensitivity in PGK-la knockout mice. PKG-la,pain,hypersensitivity,PGK-la knockout mice,mice模型,疼痛超敏反应,PKG-la基因敲除小鼠 PKG-la,pain,hypersensitivity,PGK-la knockout mice,mice,model基因表达,疼痛模型 PKG-la,pain,hypersensitivity,PGK-la knockout mice,mouse model PKG-la,pain,hypersensitivity,PGK-la knockout mice,expression PKG-la,pain,hypersensitivity,PGK-la knockout mice,mice,model基因表达,疼痛敏化,基因敲除模型
913	PPAR-RXRs are inhibited by PPAR ligands. PPAR,RXRs,inhibition,ligands,drug,target,mechanism,biochemistry,signaling pathway PPAR,RXRs,inhibition,ligands,dimers,regulation,gene expression,molecular biology,transcription factors PPAR, RXR, inhibitors, PPAR ligands, nuclear receptors PPAR,RXRs,inhibition,ligands,binding,dimers,regulation,transcription,fatty acids PPAR,RXRs,inhibition,ligands,dimers,transcription,factors,binding
914	PPAR-RXRs can be activated by PPAR ligands. PPAR, RXR, ligands, activation, transcription, nuclear receptors PPAR,RXRs,ligands,activation,molecules,retrieval,query,genetics,biochemistry,molecular biology,DNA-binding proteins,transcription factors PPAR,RXRs,ligands,activation,gene,dimers,molecules,regulation,transcription,factors,binding PPAR,RXRs,ligands,activation,transcription,factors,dimers,thyroid,hormone,receptors,differential,expression,molecular,binding,regulation,interaction PPAR, RXR, ligands, activation, transcription_factors
1339	Ultrasound guidance significantly raises the number of traumatic procedures when attempting needle insertion. ultrasound, guidance, needle insertion, traumatic procedures, significance ultrasound, guidance, needle insertion, traumatic procedures, significance ultrasound, guidance, traumatic, needle, insertion, procedures, significance ultrasound, guidance, needle insertion, traumatic procedures, significance ultrasound, guidance, needle insertion, traumatic procedures, number, significance
13	5% of perinatal mortality is due to low birth weight. perinatal,mortality,low,birth,weight,pregnancy,infant perinatal,mortality,low,birth,weight,pregnancy,pediatrics,health,obstetrics,infant perinatal,mortality,low,birth,weight,pregnancy,infant perinatal,mortality,low,birth,weight,pregnancy,pediatrics,health,infant perinatal,mortality,low,birth,weight,pregnancy,fetus,infant,health,preterm,delivery,nutrition,growth
1110	Suboptimal nutrition is not predictive of chronic disease suboptimal,nutrition,chronic,disease,predictive,factors,health,outcomes,diets,vitamins,minerals,dietary,patterns,risks nutrition, suboptimal, chronic, disease, predictive, dietary, intake, health, risk, factors, malnutrition suboptimal,nutrition,chronic,disease,predictive,factors,health,outcomes suboptimal,nutrition,chronic,disease,predictive,factors,health,outcomes,diet,malnutrition,vitamins,minerals,obesity,diabetes,cancer,hypertension,cardiovascular,mortality,prevalence,risks,associations suboptimal,nutrition,chronic,disease,prediction,health,outcome,diets,food,vitamins,minerals,calories,obesity,mortality,morbidity,prevalence,risk,factors,analysis,study,research,evidence,population,surveillance,screening,prevention,management,treatment,clinical,public,education,awareness,impact,association,correlation,statistical,methodology,biomarkers,endpoints,parameters,variables,confounders,adjustments,controls,cohorts,case,prospective,retrospective,observational
1352	Upregulation of mosGCTL-1 is induced upon infection with West Nile virus. upregulation, mosGCTL-1, West Nile virus, infection upregulation, mosGCTL-1, West Nile virus, infection, immune response, gene expression, viral infection upregulation, mosGCTL-1, West Nile, virus, infection, immune response, gene expression upregulation,mosGCTL-1,West,Nile,virus,infection,immune,response,gene-expression,molecular-biology,viral-pathogenesis upregulation,mosGCTL-1,West,Nile,virus,infection
362	During the primary early antibody response activated B cells migrate toward the inner-and outer paracortical areas where oxysterol accumulation is generated by stromal cells. antibody response, activated B cells, migration, paracortical areas, oxysterol, stromal cells early antibody response, activated B cells, migration, paracortical areas, oxysterol accumulation, stromal cells activated B cells,migrate,paracortical areas,oxysterol,stromal cells,early antibody response activated B cells,migrate,paracortical areas,oxysterol,stromal cells,primary early antibody response activated B cells,migrate,paracortical areas,oxysterol,stromal cells,early antibody response
1107	Subcutaneous fat depots undergo extensive browning processes after cold exposure. subcutaneous,fat,depots,browning,cold,exposure,processes subcutaneous,fat,deposits,browning,cold,exposure,adipose,tissue,thermogenesis,white,beige,brown,lipids,molecular,changes,metabolism,activation,energy,homeostasis,obesity,hypothermia,winter,environmental,stimulation,differentiation,angiogenesis,vascularity,heat,production,norepinephrine,CAT,DAT,UCP1,PPARγ,LIRIJP,transcription,genes,microRNAs,nanometers,ultrasound,spectroscopy,imaging,biomarkers,clinical subcutaneous,fat,depots,browning,cold,exposure,processes,adipose,tissue,thermogenesis,white,brown,beige,energy,metabolism,temperature,hormones,leptin,resistance,visceral,distribution,health,mouse,model,mammal,experiment,study,research,mechanism,activation,promotion,transformation,adipocyte,cryoexposure,cryotherapy,thermotherapy,thermogenic subcutaneous,fat,deposits,browning,cold,exposure,processes,adipose,tissue,thermogenesis,WAT,BAT,leptin,norepinephrine,UCP1,angiogenesis,metabolism,insulin,sensitivity,obesity,hypothermia,hormones,regulation,thermogenic,visceral,subcutaneous,adipocytes,DNA,mRNA,expression,energy,expansion,heat,production,gene,activation,thermogenic,factors,thermogenicity,cellular,adaptation,temperature,dependent, subcutaneous,fat,deposits,browning,processes,cold,exposure,adipose,tissue,thermogenesis,WAT,beige,brown,lipids,metabolism,activation,enzymes,angiogenesis,innervation,uncoupling,proteins,mitochondria,energy,storage,adipocytes,hypothermia,fatty,acids,transdifferentiation,diet,exercise,genetics,microenvironment,immune,cells,inflammation,leptin,resistance,temperature,thermoconductivity,insulation,biomarkers,molecular,circ
1	0-dimensional biomaterials show inductive properties. 0-dimensional,biomaterials,inductive,properties,nanomaterials,molecular,scaffold,cargo,directed,cell,growth,tissue,engineering,biocompatibility,morphogenesis 0-dimensional,biomaterials,inductive,properties,nanomaterials,molecular,self-assembling,directed,patterning,tissue,engineering,growth,factors,biomimetic,scaffold,stimuli-responsive 0-dimensional,biomaterials,inductive,properties,molecular,scaffold,nanomaterials,cancer,healing,TNF-alpha 0-dimensional,biomaterials,inductive,properties,nanomaterials,cell,tissue,growth,stimulation,biocompatibility 0-dimensional,biomaterials,inductive,properties,nanomaterials,molecular,scaffold,tissueengineering,biocompatibility,hydrogel,polymer,nanoparticle,stimulatory,effect
1226	The loss of the TET protein functions may have dire biological consequences, such as myeloid cancers. TET protein,function,myeloid,cancers,biological,consequences,loss TETprotein,function,biologicalconsequences,myeloidcancers,molecularbiology,cancerogenesis,DNAmethylation,RNAepigenetics TETprotein,function,dire,biological,consequences,myeloid,cancers TET protein,function,dire biological consequences,myeloid cancers TET protein,function,dire biological consequences,myeloid cancers
1104	Stroke patients with prior use of direct oral anticoagulants have a lower risk of in-hospital mortality than stroke patients with prior use of warfarin. stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk
1225	The locus rs647161 is associated with colorectal carcinoma. locus, rs647161, colorectal, carcinoma, genetic, association, variant rs647161,colorectal,carcinoma,locus,genevariants,molecularbiology,DNA,single nucleotide polymorphism,SNP rs647161, colorectal, carcinoma, genetic, locus, association locus, rs647161, colorectal, carcinoma, genetic, association, variant rs647161,colorectal,carcinoma,locus,genevariant,molecularbiology,cancer genetics
124	Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata. antiretroviral, therapy, tuberculosis, CD4, strata, reduction, HIV, treatment, infection Antiretroviral, therapy, tuberculosis, CD4, strata, HIV, infection, treatment, reduction, rate Antiretroviral, therapy, tuberculosis, CD4, strata, reduction, HIV, infection antiretroviral, therapy, tuberculosis, CD4, strata, reduces, HIV, infection, treatment, prevalence Antiretroviral, therapy, tuberculosis, CD4, strata, HIV, infection, treatment, reduction, rates
3	1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants. 1000genomes, genetic variation, rare variants, penetrance, common variants, genome mapping 1000 Genomes, genetic variation, rare variants, larger penetrance, common variants 1000 Genomes Project,rare variants,genetic sequence variation,penetrance,common variants,mapping,genetics,research,bioinformatics,single nucleotide polymorphisms,SNPs,DNA sequencing,human variation study,gene mapping,genomic variation analysis 1000 Genomes, genetic sequence variation, rare variants, larger penetrance, common variants 1000Genomes, genetic variation, rare variants, penetrance, common variants, genomic mapping
1344	Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging. p53, up-regulation, cancer resistance, molecular events, senescent cells, accelerated aging, lifespan, organismal aging up-regulation,p53, pathway,molecular events,cancer resistance,senescence,shortened lifespan,accelerated aging p53, up-regulation, cancer resistance, senescent cells, shortened lifespan, accelerated aging, molecular events p53, up-regulation, cancer, resistance, lifespan, senescent, cells, aging, molecular, events p53, up-regulation, cancer, resistance, lifespan, senescent, cells, aging, molecular, events
5	1/2000 in UK have abnormal PrP positivity. 1/2000, UK, abnormal, PrP, positivity, prion, disease, epidemiology 1/2000, UK, abnormal, PrP, positivity, prevalence, neuroscience, infectious disease, neurodegeneration PrP, positivity, UK, prevalence, 1/2000 1/2000, UK, abnormal, PrP, positivity, prevalence, disease, genetic, neuroscience PrP, positivity, UK, prevalence, neurodegeneration
127	Arginine 90 in p150n is important for interaction with EB1. arginine, p150grip, EB1, proteininteraction, molecularbiology, biochemistry Arginine, p150gdi, EB1, proteininteraction, aminoacid, biomolecule, cellularproteins arginine, p150grip, EB1, interaction, protein, site arginine, p150grip, EB1, protein interaction, residue, structural role arginine, p150grip, EB1, interaction, protein, residue, binding
248	Chenodeosycholic acid treatment increases whole-body energy expenditure. Chenodeoxycholic,acid,treatment,energy,expenditure,body,fat,burning,liver,metabolism Chenodeoxycholic,acid,treatment,energy,expenditure,body,metabolism,liver,hepatic,bile,gallstones,obesity,fat,burn,weight_loss,therapeutics,diet,exercise,hormones,gut,microbiome,therapeutic,effectiveness,mechanism,clinical,trials,research Chenodeoxycholic,acid,treatment,energy,expenditure,body,metabolism,liver,bile,acids,hormones,obesity,weight,loss,therapeutics,molecular,circulation,hepatic,signal,transcription,enzymes,metabolites,clinical,diabetes,cardiovascular,endoocrine,gastrointestinal,nutrition,therapy,effectiveness,mechanisms,population,studies,reviews,research,pharmacology,genetics,proteins,fatty,acids,activation,regulation,activity,biomarkers,pharmac Chenodeoxycholic,acid,treatment,energy,expenditure,whole-body,biochemistry,hormones,liver,function,dietetics,metabolism,therapeutics,molecular,biology,clinical,application,effectiveness,mechanism,physiology,nutrition,pharmacology,medicine,health,endoctrination,obesity,diabetes,lipid,metabolism,gastroenterology Chenodeoxycholic,acid,treatment,energy,expenditure,body,fat,burn,metabolism,hormone,obesity,diet,therapy,weight,reduction,hepatic,production,liver
1100	Statins increase blood cholesterol. statins, cholesterol, blood, levels, lowering, medication, heart, disease statins, cholesterol, blood, medication, lipid, level, treatment statins, cholesterol, blood, lipid, medication, treatment, cardiovascular, reduction statins, cholesterol, blood, level, medication, treatment, lowering, lipid, cardiovascular, sideffects statins, cholesterol, blood, medication, lipid, treatment, heart, health
1221	The genomic aberrations found in matasteses are very similar to those found in the primary tumor. genomic, aberrations, metastases, primary, tumor, similarity genomic, aberrations, metastases, primary, tumor, similarity genomic, aberrations, metastases, primary, tumor, similar genomic, aberrations, metastases, primary, tumor, similar genomic, aberrations, metastases, primary, tumor, similar
128	Arterioles have a larger lumen diameter than venules. arterioles, lumen, diameter, venules arterioles, lumen, diameter, venules arterioles, lumen, diameter, venules arterioles, lumen, diameter, venules arterioles, lumen, diameter, venules
249	Chenodeosycholic acid treatment reduces whole-body energy expenditure. Chenodeoxycholic,acid,treatment,energy,expenditure,body,reduce Chenodeoxycholic,acid,treatment,energy,expenditure,body,reduce,liver,diet,metabolism,obesity,human,animal,study,clinical,experiment Chenodeoxycholic,acid,treatment,energy,expenditure,reduces,body,metabolism,hepatic,biliary Chenodeoxycholic,acid,treatment,energy,expenditure,reduces,body,metabolism,obesity,diet,fat,burn,hepatic,lipid,pancreatic Chenodeoxycholic,acid,treatment,energy,expenditure,body,weight,metabolism,human,clinical,population
129	Articles published in open access format are less likely to be cited than traditional journals. openaccess,citation,trend,traditionaljournals,publishing,academic,research,impact,frequency,accessibility,journalimpactfactor,OA/articles,publicationformat,citationrate open access,journals,citation,t传统期刊,impact因子 open access,citation,t传统期刊,journal,retrieval,publishing格式,impact因子 openaccess,citation,t传统期刊,impactfactor,accessibility,publishing格式,academicpublishing open access,journal articles,citation,traditional journals,retrieval,publication format,popularity
800	Modifying the epigenome in the brain affects the normal human aging process by affecting certain genes related to neurogenesis. epigenome, brain, aging, neurogenesis, genes epigenome, brain, aging, neurogenesis, genes epigenome, brain, aging, neurogenesis, gene expression epigenome, brain, aging, neurogenesis, gene modification epigenome, brain, aging, neurogenesis, genes
921	Participating in six months of physical activity improves cognitive functioning. physical activity,cognitive functioning,months,retrieval,improves,participating physicalactivity,cognitivefunctioning,months,retrieval,improvement,participation physicalactivity,cognitivefunctioning,months,retrieval,improvement,participation physical activity,cognitive functioning,six months,improvement,participation,retrievalKeywords:Physical,Activity,Cognitive,Functioning,Six,Months,Improvement,Participation,Retrieval physical activity,cognitive functioning,months,retrieval,improves,participating
922	Patients in stable partnerships have a faster progression from HIV to AIDS. HIV, AIDS, stable partnerships, patient progression HIV, AIDS, stable partnerships, patient progression HIV, AIDS, stable partnerships, patients, progression HIV, AIDS, stable partnerships, progression, patients HIV, AIDS, stable partnerships, patient progression
805	Monoclonal antibody targeting of N-cadherin inhibits metastasis. Monoclonal antibody,N-cadherin,metastasis,inhibition,cancertherapy,biochemistry,molecularbiology,tumorprogression monoclonal抗体,N-cadherin,抑制,转移,靶向治疗 monoclonal抗体,N-cadherin,抑制,转移,靶向疗法 monoclonal antibody,N-cadherin,metastasis,inhibition,cancertherapy,biochemistry,molecularbiology monoclonal抗体,N-cadherin,抑制,转移,靶向治疗
808	Most termination events in Okazaki fragments are sequence specific. Okazaki fragments, termination events, sequence specificity Okazaki fragments, termination events, sequence specificity, DNA replication Okazaki fragments, termination events, sequence specificity Okazaki fragments, termination events, sequence specificity, DNA replication Okazaki fragments, termination events, sequence specificity
1121	Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites. synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites
1363	Venules have a thinner or absent smooth layer compared to arterioles. venules, arterioles, smooth muscle, thickness, blood vessels venules, arterioles, smooth muscle, thickness, blood vessels venules, arterioles, smooth muscle, thickness, blood vessels venules, arterioles, smooth muscle, blood vessels, diameter, endothelium venules, arterioles, smooth muscle, blood vessels, diameter, endothelium
1241	The myocardial lineage develops from cardiac progenitors of mesodermal origin. myocardial, lineage, cardiac, progenitors, mesodermal myocardial, lineage, cardiac, progenitors, mesodermal, development myocardial, lineage, cardiac, progenitors, mesodermal myocardial, lineage, cardiac, progenitors, mesodermal, development myocardial, lineage, cardiac, progenitors, mesodermal, development
1362	Venules have a larger lumen diameter than arterioles. venules, lumen, diameter, arterioles venules,arterioles,lumen,diameter,anatomy,vasculature venules,arterioles,lumen,diameter,retrieval,anatomy venules, arterioles, lumen, diameter, anatomy venules, arterioles, lumen, diameter, blood vessels
491	HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years HNF4A,mutations,diabetes,carriers,age,14years HNF4A,mutations,diabetes,carriers,age,14years HNF4A,mutations,diabetes,carrier,age,14 years HNF4A,mutations,diabetes,carrier,age,14years HNF4A,mutations,diabetes,carriers,age,14years
130	Articles published in open access format are more likely to be cited than traditional journals. openaccess,citation,t传统期刊,impact因子,publishing模型,学术开放获取,引用率,期刊类型 openaccess,citation,tendency,traditionaljournals,retrieval,publicationformat,academicarticles,membership,impactfactor,publishingmodel,readership,accessibility,scientificcommunication,effectiveness,popularity,visibility,digitalage,openaccessjournals,impactoncitationcounts openaccess,citations,traditionaljournals,research,publishing,model openaccess,citations,traditionaljournals,researcharticles,publicationformat,journalimpact,freerelease,academicpublishing open access,journals,citation,publishing,retrieval,articles,format,probability,traditional journals
132	Aspirin inhibits the production of PGE2. aspirin,PGE2,inhibition,prostaglandin,E2,pain,retrieval,molecular,salicylicacid aspirin,PGE2,inhibition,prostaglandin E2,anti-inflammatory,analgesic aspirin,PGE2,inhibition,prostaglandin,E2,nsaid analgesic aspirin, inhibit, PGE2, prostaglandin, production aspirin, inhibits, PGE2, prostaglandin, production
133	Assembly of invadopodia is triggered by focal generation of phosphatidylinositol-3,4-biphosphate and the activation of the nonreceptor tyrosine kinase Src. invadopodia, phosphatidylinositol-3,4-biphosphate, Src, assembly, focal, activation, nonreceptor tyrosine kinase assembly, invadopodia, phosphatidylinositol-3,4-biphosphate, focal, activation, nonreceptor tyrosine kinase, Src assembly, invadopodia, phosphatidylinositol-3,4-biphosphate, activation, nonreceptor tyrosine kinase, Src assembly, invadopodia, phosphatidylinositol-3,4-biphosphate, focal, generation, nonreceptor, tyrosine, kinase, Src, activation Assembly, invadopodia, phosphatidylinositol-3,4-biphosphate, focal, generation, activation, nonreceptor, tyrosine, kinase, Src
1359	Varenicline monotherapy is more effective after 12 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion. varenicline, monotherapy, effectiveness, nicotine, replacement, bupropion, 12 weeks varenicline, monotherapy, effectiveness, 12 weeks, nicotine replacement, bupropion, smoking cessation varenicline, monotherapy, effectiveness, nicotine, replacement, bupropion, 12, weeks, treatment varenicline, monotherapy, effectiveness, nicotine, replacement, bupropion, treatment, duration, 12 weeks varenicline, monotherapy, effectiveness, nicotine, replacement, therapies, bupropion, comparison, 12, weeks
137	Asymptomatic visual impairment screening in elderly populations does not lead to improved vision. asymptomatic, visual, impairment, screening, elderly, populations, outcomes, vision, health, interventions asymptomatic, visual, impairment, screening, elderly, populations, outcomes, vision, prevention asymptomatic, visual, impairment, screening, elderly, populations, vision, outcomes asymptomatic, visual, impairment, screening, elderly, populations, improved, vision asymptomatic, visual, impairment, screening, elderly, populations, outcomes, vision, health, interventions
1232	The minor G allele of FOXO3 is related to more severe symptoms of Crohn's Disease. FOXO3, G allele, Crohn's Disease, severity, gene variant FOXO3,G allele,Crohn's Disease,symptomsseverity FOXO3,G allele,Crohn's Disease,symptoms severeness FOXO3,G allele,Crohn's Disease,symptoms,genetics,severity FOXO3,G allele,Crohn's Disease,symptoms,genetics,RNA binding protein
811	Mutant mice lacking SVCT2 have greatly increased ascorbic acid levels in both brain and adrenals. Mutant,mice,SVCT2,ascorbicacid,brain,adrenals mutant,mice,SVCT2,ascorbicacid,brain,adrenals mutant,mice,SVCT2,ascorbic acid,brain,adrenals mutant,mice,SVCT2,ascorbicacid,brain,adrenals mutant,mice,SVCT2,ascorbicacid,brain,adrenals
814	Mutations in G-Beta protein GNB2 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway. Mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,subunits,AKT,activation mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,subunits,activation,AKT,signaling/pathway Mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,subunits,AKT,activation mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,subunits,AKT,activation mutations,G-Beta,GNB2,cancers,G-alpha,AKT,activation,interaction
936	Peroxynitrite is required for nitration of TCR/CD8. Peroxynitrite,nitration,TCR,CD8,T-cell,retrieval,molecularbiology-immunology Peroxynitrite,nitration,TCR,CD8,T-cell,retrieval,molecule Peroxynitrite,nitration,TCR,CD8,T-cell,retrieval,molecule,immune response Peroxynitrite,nitration,TCR,CD8,T cell,retrieval,query,improve Peroxynitrite,nitration,TCR,CD8,T cell,retrieval,improve
36	A deficiency of vitamin B12 increases blood levels of homocysteine. vitamin,B12,homocysteine,deficiency,blood,levels vitamin B12, deficiency, homocysteine, blood levels vitamin B12, deficiency, homocysteine, blood levels vitamin B12, deficiency, homocysteine, blood levels vitamin,B12,homocysteine,deficiency,bloodlevels
1132	TCR/CD3 microdomains are a required to induce the immunologic synapse to activate T cells. TCR, CD3, microdomains, immunologic synapse, T cells, activation TCR, CD3, microdomains, immunologic synapse, T cells, activation TCR, CD3, microdomains, immunologic synapse, T cells, activation TCR, CD3, microdomains, immunologic synapse, T cells, activation TCR, CD3, microdomains, immunologic synapse, T cells, activation
1130	T regulatory cells (tTregs) lacking αvβ8 are more adept at suppressing pathogenic T-cell responses during active inflammation. Treg, tTregs, αvβ8, suppression, inflammation, pathogenic, immune response Treg, αvβ8, inflammation, suppression, pathogenic, T-cells Treg, tTregs, αvβ8, inflammation, suppression, pathogenic, T-cells Treg, tTregs, αvβ8, inflammation, suppression, pathogenic T-cells Treg, tTregs, αvβ8, inflammation, suppression, pathogenic T-cells
380	Enhanced early production of inflammatory chemokines improves viral control in the lung. Enhanced, early, production, inflammatory, chemokines, viral, control, lung Enhanced, early, production, inflammatory, chemokines, viral, control, lung Enhanced, early, production, inflammatory, chemokines, viral, control, lung Enhanced, early, production, inflammatory, chemokines, viral, control, lung Enhanced, early, production, inflammatory, chemokines, viral, control, lung
1370	Vitamin D deficiency is unrelated to birth weight. vitamin,D,deficiency,birth,weight,pregnancy,evidence,research,studies,obesity,malnutrition,infant,growth vitamin D, deficiency, birth weight, unrelated, nutrition, prenatal, health vitamin D, deficiency, birth weight, unrelated, pregnancy, nutrition, fetal development Vitamin D, deficiency, birth weight, unrelated, pregnancy, nutrition vitamin D, deficiency, birth weight, unrelated, pregnancy, nutrition, fetal development
261	Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO. Chronic,aerobic,exercise,endothelial,function,vasodilating,mechanisms,NO,nitricoxide Chronic,aerobic,exercise,endothelial,function,vasodilating,mechanisms,NO chronic,aerobicexercise,endothelialfunction,vasodilation,NO,mechanisms Chronic,aerobic,exercise,endothelial,function,vasodilating,mechanisms,NO Chronic,aerobicexercise,endothelialfunction,vasodilation,NO,nitricoxide
141	Auditory entrainment is strengthened when people see congruent visual and auditory information. auditory,entrainment,visual,audio,synchronization,congruence,cognition,sensory,integration,time,matching auditory,entrainment,visual,information,congruence,strengthened AuditoryEntrainment, VisualInformation, Congruence, Perception, Synchronization, CognitiveProcessing auditory,entrainment,visual,audio-visual,congruence,synchronization,cognition,neuroscience,psychology,human perception AuditoryEntrainment, VisualInformation, Congruence, Perception, Synchronization, Neurofeedback, CognitiveProcessing
142	Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies. autologous, transplantation, mesenchymal, stem cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin, receptor, antibodies mesenchymal, stem, cells, autologous, transplantation, opportunistic, infections, anti-interleukin, receptor, antibodies, induction, therapy autologous, transplantation, mesenchymal, stem cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies
384	Epidemiological disease burden from noncommunicable diseases is more prevalent in low economic settings. Epidemiology, Disease Burden, Noncommunicable Diseases, Low Economic Settings Epidemiology, Noncommunicable, Diseases, Prevalence, Economic, Settings, Burden Epidemiology, Disease burden, Noncommunicable diseases, Low income, Prevalence Epidemiology, Noncommunicable, Diseases, Burden, Low, Economic, Settings Epidemiology, Disease Burden, Noncommunicable Diseases, Low Income, Economic Settings
143	Autologous transplantation of mesenchymal stem cells causes fewer opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies. mesenchymal, stem, cells, autologous, transplantation, opportunistic, infections, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem cells, opportunistic infections, anti-interleukin-2, receptor antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies
385	Epigenetic modulating agents (EMAs) modulate antitumor immune response in a cancer model system. Epigenetic, modulating, agents, antitumor, immune, response, cancer, model, system Epigenetics,modulating,agents,antitumor,immune,response,cancer,model/system Epigenetic,modulating,agents,antitumor,immune,response,cancer,model/system Epigenetic, modulating, agents, antitumor, immune, response, cancer, model, system Epigenetics,modulating,agents,antitumor,immune,response,cancer,model.system
386	Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations. errors, peripheral, IV, drug, administration, bolus, multiple-step, medicine, preparation errors, peripheral, IV, drug, administration, bolus, multiple-step, medicine, preparation errors, peripheral, IV, drug, administration, bolus, preparation, multiple-step, medication errors, peripheral, IV, drug, administration, bolus, multiple, step, medicine, preparation errors, peripheral, IV, drug, administration, bolus, preparation, multiple-step, medication, nursing, complications
1368	Vitamin D deficiency effects the term of delivery. Vitamin D, deficiency, pregnancy, delivery, term, maternal, fetal, health, immunity Vitamin D, deficiency, pregnancy, delivery, term, maternal, neonatal, health, outcomes Vitamin D, deficiency, pregnancy, delivery, term, maternal health Vitamin D, deficiency, pregnancy, delivery, term, effect Vitamin D, deficiency, pregnancy, delivery, term, maternal, neonatal, health, outcome
146	Autologous transplantation of mesenchymal stem cells has lower rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies. autologous, transplantation, mesenchymal, stem, cells, rejection, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, rejection, induction, therapy, anti-interleukin, antibodies autologous, transplantation, mesenchymal, stem, cells, rejection, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, rejection, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, rejection, induction, therapy, anti-interleukin, antibodies, interleukin-2, receptor
388	Ethanol stress decreases the expression of IBP in bacteria. Ethanol, stress, expression, IBP, bacteria Ethanol, stress, expression, IBP, bacteria ethanol, stress, expression, IBP, bacteria Ethanol, stress, bacteria, IBP, expression Ethanol, stress, bacteria, IBP, expression
268	Cold exposure increases BAT recruitment. Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,energy expenditure,fat metabolism,non-shivering thermogenesis Cold exposure,BAT,brown adipose tissue,recruitment,winter,hypothermia,thermogenesis,metabolism,energy expenditure,adipocytes cold exposure,BAT,brown adipose tissue,thermogenesis,winter,hypothermia,resistance exercise,energy expenditure,fat metabolism cold exposure,BAT,brown adipose tissue,thermogenesis,weight loss,hypothermia,endurance,insulin sensitivity Cold exposure,BAT,brown adipose tissue,recruitment,winter,hypothermia,thermogenesis
1245	The one-child policy has been successful in lowering population growth. one-child,policy,successful,population,growth,China,计划生育,生育政策,人口增长 one-child,policy,successful,lowering,population,growth,China,reproductive,control,effectiveness one-child,policy,successful,lowering,population,growth,china,population control,policy effectiveness one-child,policy,successful,population,growth,China,retrieval,query one-child,policy,successful,lowering,population,growth,china,population控制,计划生育政策,人口增长率
148	Autophagy declines in aged organisms. autophagy, aging, senescence, age-related, cellular degradation, lifespan, biological process, gerontology autophagy, aging, senescence, cellular degradation, longevity, age-related, biomarkers, lifespan, mitochondrial dysfunction, immune response autophagy, aging, senescence, mitochondria, lysosomes, autophagosomes, protein degradation, cellular maintenance, lifespan, gerontology autophagy, aging, senescence, cellular degradation, age-related, lifespan, mitochondrial function, protein turnover, lysosomes, macroautophagy, autophagosome autophagy, aging, senescence, cellular degradation, lifespan, mitochondria, ubiquitin-proteasome system
269	Cold exposure reduces BAT recruitment. Cold exposure,BAT,brown adipose tissue,recruitment,winter,hypothermia,thermogenesis,mouse,model,metabolism,energy expenditure,temperature regulation Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,mouse,model,human,metabolism,fat,burning,energy expenditure,activation,adipocytes,temperature regulation,non-shivering thermogenesis Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,hormones,metabolism,energy expenditure,fat metabolism,adaptive thermogenesis cold exposure,BAT,brown adipose tissue,thermogenesis,energy metabolism,fatigue,weight loss,hypothermia,winter adaptation,cryotherapy,non-shivering thermogenesis Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,mouse,experiment,energy expenditure
820	N-terminal cleavage increases success identifying transcription start sites. N-terminal,cleavage,transcription,start,sites,molecular,biology,genetics,biotechnology,omics,analysis,proteomics,nucleicacid N-terminal,cleavage,transcription,start,sites,identification,molecular,bioinformatics,genomics,rna,analysis N-terminal,cleavage,transcription,start,sites,retention,sequence,prediction,biological,analysis N-terminal, cleavage, transcription, start, sites, proteomics, RNA, sequencing, bioinformatics N-terminal,cleavage,transcription,start,sites,retrieval,improve
700	Localization of PIN1 in the Arabidopsis embryo does not require VPS9a PIN1, localization, Arabidopsis, embryo, VPS9a, protein trafficking PIN1, localization, Arabidopsis, embryo, VPS9a, protein trafficking, endomembrane system, plant biology, cellular localization Localization,PIN1,Arabidopsis,embryo,VPS9a,retrieval,bioinformatics,microscopy,protein localization PIN1 localization, Arabidopsis, embryo, VPS9a, protein trafficking, cellular localization, plant biology Localization,PIN1,Arabidopsis,embryo,VPS9a,retrieval,bioinformatics,microscopy,cell biology,plant science
821	N-terminal cleavage reduces success identifying transcription start sites. N-terminal, cleavage, transcription, start, sites, proteomics, RNA, sequencing, bioinformatics N-terminal,cleavage,transcription,start,sites,identification,success,proteomics,mass,spectrometry,RNA,sequencing,genomics,biological,processes,experimental,techniques N-terminal, cleavage, transcription, start, sites, identification, proteomics, bioinformatics, RNAprocessing N-terminal, cleavage, transcription, start, sites, proteomics, RNA, sequencing, biotechnology, geneexpression, molecularbiology N-terminal,cleavage,transcription,start,sites,reduces,identification,mRNA,sequence,biological,analysis
702	Localization of PIN1 in the roots of Arabidopsis does not require VPS9a PIN1, localization, roots, Arabidopsis, VPS9a, protein trafficking, cellular localization, plant biology PIN1, localization, roots, Arabidopsis, VPS9a, protein trafficking, Golgi apparatus, plant biology Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval,requirement Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval,requirement Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval,biochemistry,cell biology,plant science,molecular biology,localization study,protein localization,cellular localization
823	N348I mutations cause resistance to zidovudine (AZT). N348I, mutations, zidovudine, AZT, resistance N348I, mutations, zidovudine, AZT, resistance N348I mutation,zidovudine,AZT,resistance,HIV N348I, mutations, zidovudine, AZT, resistance N348I,mutations,zidovudine,AZT,resistance,Viral,retrovirus,HIV
42	A high microerythrocyte count raises vulnerability to severe anemia in homozygous alpha (+)- thalassemia trait subjects. high microerythrocyte count, severe anemia, homozygous, alpha (+)-thalassemia, trait microerythrocyte,count,anemia,homozygous,alpha,+,-,thalassemia,trait,vulnerability microerythrocyte,count,vulnerability,severe,anemia,homozygous,alpha,+,-,thalassemia,trait microerythrocyte,count,vulnerability,severe,anemia,homozygous,alpha,thalassemia,trait high microerythrocyte count, severe anemia, homozygous alpha (+)-thalassemia, trait subjects
48	A total of 1,000 people in the UK are asymptomatic carriers of vCJD infection. vCJD, asymptomatic, carriers, UK, infection asymptomatic, vCJD, infection, UK, people vCJD, asymptomatic, UK, carriers, total, people asymptomatic, vCJD, UK, infection, people asymptomatic, vCJD, infection, UK, people
49	ADAR1 binds to Dicer to cleave pre-miRNA. ADAR1,Dicer,pre-miRNA,cleavage,binding,microRNA-processing ADAR1,Dicer,pre-miRNA,cleavage,binding,microRNAprocessing ADAR1,Dicer,pre-miRNA,cleavage,binding,microRNAprocessing ADAR1,Dicer,pre-miRNA,cleavage,microRNAprocessing ADAR1,Dicer,pre-miRNA,cleavage,binding,microRNA-processing
1385	cSMAC formation enhances weak ligand signalling. cSMAC, protein, ligand, signaling, interaction, biochemistry, molecular, cell biology, pathway, regulation cSMAC, protein, signaling, pathway, ligand, interaction, biology, receptor, activation, mechanism cSMAC, protein, ligand binding, signaling pathway, biochemistry, molecular biology cSMAC, formation, weak, ligand, signalling, protein, interaction, biology, molecular, pathway cSMAC, protein, ligand, signaling, interaction, mechanism, biology, cellular
1021	Rapid up-regulation and higher basal expression of interferon-induced genes reduce survival of granule cell neurons that are infected by West Nile virus. Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, reduce, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, West, Nile, virus Rapid, up-regulation, interferon, genes, basal, expression, survival, granule, neuron, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus
1020	Rapid up-regulation and higher basal expression of interferon-induced genes increase survival of granule cell neurons that are infected by West Nile virus. Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, West, Nile, virus Rapid, up-regulation, interferon, induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, neuron, infected, West Nile, virus
1262	The repair of Cas9-induced double strand breaks in human DNA is error-prone. Cas9, doublestrandbreaks, humanDNA, repair, errorprone, genomeediting Cas9, doublestrandbreaks, DNArepair, human, errorprone Cas9, doublestrandbreaks, DNArepair, humancells, errorprone, geneediting Cas9, doublestrandbreaks, humanDNA, repair, errorprone Cas9, doublestrandbreaks, humanDNA, repair, errorprone
1140	Taking 400mg of α-tocopheryl acetate helps to prevent prostate cancer. α-tocopheryl acetate,megadoses,prostate,cancer,prevention,vitamin,E,400mg α-tocopheryl acetate,male,fat soluble,vitamin E,prostate,cancer,prevention,dose α-tocopheryl,acetate,male,cancer,prostate,vitamin,E,dosage,benefits α-tocopheryl,acetate,male,cancer,prostate,vitamin,E,dose,prevention α-tocopheryl,acetate,male,cancer,prostate,vitamin,E,dosage,benefits,prevention
1382	aPKCz causes tumour enhancement by affecting glutamine metabolism. aPKCz,tumour,enhancement,glutamine,metabolism,cancer/signaling/pathway aPKCz,tumour,enhancement,glutamine,metabolism,cancer,pathway,signal,proliferation,growth aPKCz,tumour,enhancement,glutamine,metabolism,cancer,glioblastoma,signalling,proliferation,survival,network,regulation aPKCz,tumour,enhancement,glutamine,metabolism,cancerbiosignaling aPKCz,tumour,glutamine,metabolism,cancer,pathway,signalling,proliferation,growth
274	Combination nicotine replacement therapies with varenicline or bupropion lead to significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy. nicotine, replacement, therapies, varenicline, bupropion, abstinence, rates, long-term, 52, weeks, monotherapy nicotine, replacement, therapies, varenicline, bupropion, abstinence, rates, long-term, 52, weeks, combination, smoking, cessation, treatment, efficacy, quit, smokingcessation, pharmaceuticals, addiction, treatmentmethods nicotine, replacement, therapies, varenicline, bupropion, abstinence, rates, week, monotherapy nicotine, replacement, therapies, varenicline, bupropion, abstinence, rates, 52, weeks, monotherapy nicotine, replacement, therapies, varenicline, bupropion, abstinence, rates, 52, weeks, monotherapy
1019	Rapid phosphotransfer rates govern fidelity in two component systems phosphotransfer, fidelity, two, component, systems, signaling, bacteria, kinetics, regulation Rapid, phosphotransfer, fidelity, two, component, systems, bacterial, signal, transduction, regulatory, proteins Rapid, phosphotransfer, fidelity, two, component, systems, bacteria, signal, transduction, regulation phosphotransfer, fidelity, two, component, systems, rapid, signal, transduction Rapid, phosphotransfer, fidelity, two, component, systems, bacterial, signaling, regulation, kinetics
275	Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is effective at treating KRAS mutant tumors. phosphatidylinositide, 3-kinase, MEK, KRAS, tumor, treatment, inhibitor, combinationtherapy phosphatidylinositide, 3-kinase, MEK, KRAS, tumor, treatment, inhibition, oncology, signaling, pathway, drugcombination phosphatidylinositide, 3-kinase, MEK, KRAS, tumor, treatment, inhibitor phosphatidylinositide, 3-kinase, MEK, KRAS, tumors, combination, treatment, effectiveness phosphatidylinositide,3-kinase,inhibitors,MEK,KRAS,tumors,effective,combinationtherapy
1259	The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up. breast cancer,tamoxifen,metabolism,genetic make-up,treatment outcome breast cancer, tamoxifen, metabolism, genetic make-up, treatment outcome breast cancer,tamoxifen,metabolism,genetic make-up,treatment outcome breast cancer, tamoxifen, metabolism, genetic makeup, treatment outcome breast cancer,tamoxifen,metabolism,genetic make-up,treatment outcome
1137	TNFAIP3 is a tumor suppressor in glioblastoma. TNFAIP3,tumor,suppressor,glioblastoma,cancer,genetics,molecular,biology,prognosis,therapy,expression,miRNA,DNA methylation TNFAIP3,glioblastoma,tumor suppressor,inflammation,microenvironment,genetics,molecular biology,cancerbiology,pathway,prognosis,therapy,survival TNFAIP3,tumor,suppressor,glioblastoma,molecular,biology,cancer,pathway,genetics,expression,therapy,microarray,prognosis TNFAIP3,tumor,suppressor,glioblastoma,microRNA,expression,prognosis,pathway,molecular biology,cancer biology,genetics TNFAIP3,tumor,suppressor,glioblastoma,cancer,genetics,molecular,bioinformatics,prognosis,therapy,disease,pathway,expression,mutation
1379	Women with a higher birth weight are more likely to develop breast cancer later in life. birthweight, breastcancer, women, likelihood, development, adulthood birth weight, breast cancer, women, risk因素, later life birth weight, breast cancer, women, likelihood, development birth weight, breast cancer, women, likelihood, development, age birthweight, breastcancer, women, development, laterlife
399	Exposure to fine particulate air pollution is relate to anxiety prevalence. fine particulate matter, air pollution, anxiety, prevalence, epidemiology, health impact, respiratory pollution, mental health exposure,fine,particulate,pollution,anxiety,prevalence,health,environmental,risk,factor,study,association,cardiopulmonary,mental,illness,disease,population,study,meta-analysis,research,impact,correlation,public,health,effects exposure,fine,particulate,pollution,anxiety,prevalence,health,effects,airquality,environmentalimpact exposure,fine,particulate,air,pollution,anxiety,prevalence,health,effects,risk,factors,environmental,mental,illness,disease,statistics,study,correlation,impact exposure,fine,particulate,air,pollution,anxiety,prevalence,health,effects,risk,factors,environmental,mental,illness
279	Commelina yellow mottle virus' (ComYMV) genome consists of 7489 baise pairs. Commelinayellowmottlevirus, ComYMV, genome, basepairs, DNA, plantvirus Commelina_yellow_mottle_virus, ComYMV, genome, base_pairs, DNA_virus Commelina, yellow, mottle, virus, ComYMV, genome, base, pairs Commelinayellowmottlevirus, ComYMV, genome, basepairs, DNA, molecularbiology Commelina_yellow_mottle_virus,Base_pairs,Genome_length,ComYMV
1014	Rapamycin decreases the concentration of triacylglycerols in fruit flies. Rapamycin, triacylglycerols, fruit flies, lifespan, metabolism, nutrition, aging, gerontology, biochemistry, genetics, insulin, signaling Rapamycin, triacylglycerols, fruit flies, longevity, metabolism, gerontology, diet, lifespan, lipids Rapamycin, triacylglycerols, fruit flies, longevity, metabolism, aging, lipid, diet, intervention Rapamycin, triacylglycerols, fruit flies, lipid metabolism, aging, lifespan, metabolism, nutrition, genetics Rapamycin, triacylglycerols, fruit flies, lipid metabolism, longevity, aging, metabolism, intervention, biochemistry, gerontology, nutrition, health, genetics
830	NF2 (Merlin) causes phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila by activating LATS1/2 kinases. NF2, Merlin, phosphorylation, YAP, cytoplasmic sequestration, LATS1, LATS2, Drosophila, kinase NF2, Merlin, phosphorylation, YAP, cytoplasmic, sequestration, LATS1, LATS2, kinases, Drosophila NF2, Merlin, phosphorylation, YAP, cytoplasmic, sequestration, LATS1, LATS2, Drosophila, kinase NF2, Merlin, phosphorylation, YAP, cytoplasmic sequestration, LATS1/2, Drosophila NF2, Merlin, phosphorylation, YAP, cytoplasmic sequestration, LATS1/2, Drosophila, kinase
831	NF2 (Merlin) prevents phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila. NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila
1012	Radioiodine treatment of non-toxic multinodular goitre reduces thyroid volume. Radioiodine,treatment,non-toxic,multinodular,goitre,thyroid,volume,reduction,thyroidectomy,euthyroid,symptomatic,management,radioactive,i-131,nontoxic,iodine,therapy,hypothyroidism,radiation,dose,efficacy,safety,sideffects,complications Radioiodine,treatment,non-toxic,multinodular goitre,thyroid volume,reduction,thyroidectomy,management,thyroiditis,nodules,hypothyroidism,radioactive iodine Radioiodine,treatment,non-toxic,multinodular,goitre,thyroid,volume,retrieval,query Radioiodine,treatment,non-toxic,multinodular goitre,thyroid volume,reduction,thyroidectomy,euthyroid,iodine-131,radioactive iodine,thyroid hormone levels,nodules,gland volume,thyroiditis,hyperthyroidism,hypothyroidism,thyroid function tests,radiotherapy,management,thyroid nodules,thyroid surgery,iodine therapy,radioactive isotopes Radioiodine,treatment,non-toxic,multinodular goitre,thyroid volume,reduction
832	NFAT4 activation requires IP3R-mediated Ca2+ mobilization. NFAT4, activation, IP3R, Ca2+, mobilization, signaling, calcium, regulation, immunology, transcription, factor NFAT4, activation, IP3R, Ca2+, mobilization, signaling, calcium, regulation, immune, response, transcription, factor NFAT4, activation, IP3R, Ca2+, mobilization, signaling, calcium, regulation, cell, biology, transcription, factor NFAT4, activation, IP3R, Ca2+, mobilization, signaling, calcium, regulation, immunology, physiology NFAT4, activation, IP3R, Ca2+, mobilization, signaling, pathway, calcium, regulation, transcription, factor
834	NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates. NOX2, peroxynitrite, nitrogen intermediates, pathway, generation NOX2, peroxynitrite, nitrogen intermediates, pathways, generation NOX2, peroxynitrite, nitrogen intermediates, pathway, generation NOX2, peroxynitrite, nitrogen intermediates, oxidative stress, signaling pathways NOX2, peroxynitrite, nitrogen intermediates, pathway, generation
956	Pleiotropic coupling of GLP-1R to intracellular effectors promotes distinct profiles of cellular signaling. GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, coupling GLP-1R, intracellular, effectors, pleiotropy, cellular, signaling, profiles GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, distinct, profiles GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, coupling GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, distinct, profiles
50	AIRE is expressed in some skin tumors. AIRE,skin,tumors,expression,molecular biology,immunology,cancer biology,DNA sequence,protein expression AIRE,skin,tumors,expression,immunology,molecular biology,cancer immunology AIRE,skin,tumors,expression,immunology,molecular biology,cancerbiology AIRE,skin,tumors,expression,gene,molecular biology,CaImmunology AIRE,tumors,skin,cancer,gene,expression
715	Low expression of miR7a does represses target genes and exerts a biological function in ovaries. miR7a, low expression, target genes, biological function, ovaries miR7a, low expression, target genes, biological function, ovaries miR7a, low expression, target genes, biological function, ovaries miR7a, low expression, repression, target genes, biological function, ovaries miR7a, low expression, target genes, biological function, ovaries
957	Podocytes are motile and migrate in the presence of injury. Podocytes,motility,injury,migration,glomerulus,renal,tissue repair Podocytes,motility,injury,migration,renal,tissue repair,specialized cells Podocytes,motility,injury,migration,renal,tissue repair Podocytes,motility,injury,migration,tissue repair,renal physiology,cytoskeleton,focal segmental glomerulosclerosis Podocytes,motility,injury,migration,renal,tissue repair,differentiation
51	ALDH1 expression is associated with better breast cancer outcomes. ALDH1, breast cancer, outcome, prognosis, biomarker ALDH1, breast cancer, outcome, prognosis, expression, biomarker ALDH1, breast cancer, prognosis, outcomes, biomarker ALDH1, breast cancer, prognosis, outcome, biomarker ALDH1, breast cancer, outcome, prognosis, expression, biomarker
716	Low expression of miR7a exerts a biological function in testis. miR7a, testis, low expression, biological function miR7a, low expression, biological function, testis miR7a, testis, low expression, biological function miR7a, low expression, testis, biological function miR7a, low expression, biological function, testis
837	NR5A2 is important in development of endometrial tissues. NR5A2,endometrial,tissues,development,gene,function,molecular,biology,reproductive,medicine NR5A2,endometrial,tissues,development,gene,function NR5A2,endometrial,tissues,development,gene,function,molecular,biology,reproductivemedicine NR5A2,endometrial,tissues,development,gene,function NR5A2,endometrial,tissues,development,gene,function,molecularbiology
53	ALDH1 expression is associated with poorer prognosis in breast cancer. ALDH1, breast cancer, prognosis, gene expression ALDH1, breast cancer, prognosis, expression, oncology, biomarker, tumor markers ALDH1, breast cancer, prognosis, expression, biomarker, oncology ALDH1, breast cancer, prognosis, expression, poor outcome ALDH1, breast cancer, prognosis, expression, biomarker
718	Low nucleosome occupancy correlates with low methylation levels across species. nucleosome, occupancy, methylation, species, epigenetics, chromatin, DNA, correlation low,nucleosome,occupancy,methylation,species,genetics,epigenetics,biology,DNA,chromatin,stability,conservation,analysis low,nucleosome,occupancy,methylation,species,genetics,epigenetics,bioinformatics,molecular,biology,evoinformatics low,nucleosome,occupancy,methylation,species,bioinformatics,epigenetics,DNA,genetics,histone,chromatin nucleosomes,methylation,species,evolution,genetics,epigenetics,histones,chromatin,DNA
839	Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles. Nanoparticles,aptamers,lipid,nanoparticles,cell targeting,specific cell types Nanoparticles,aptamers,lipid,nanoparticles,cell,targeting,specific Nanoparticles,aptamers,lipid,nanoparticles,cell,types,targeting,delivery,biotechnology,molecularmedicine,biosensors Nanoparticles,aptamers,lipid,nanoparticles,cell,targeting,specificity Nanoparticles, aptamers, lipid nanoparticles, targeted delivery, cell types
54	AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs. AMP-activated protein kinase, activation, inflammation, fibrosis, lungs AMP-activated protein kinase, AMPK, inflammation, fibrosis, lungs, activation, cellular response, metabolic stress, signaling pathway AMP-activated protein kinase, AMPK, inflammation, fibrosis, lungs AMP-activated protein kinase, activation, inflammation, fibrosis, lungs AMP-activated protein kinase, AMPK, inflammation, fibrosis, lungs, activation, cellular metabolism, signaling pathway, therapeutic target, metabolic stress
56	APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation causing GABA neuron degeneration. APOE4,iPSC,neurons,AlphaBeta,tau phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration
57	APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation, delaying GABA neuron degeneration. APOE4,iPSC,differentiated neurons,AlphaBeta protein,tau phosphorylation,GABA neurons,neuron degeneration APOE4,iPSC,differentiated neurons,AlphaBeta protein,tau phosphorylation,GABA neurons,neuron degeneration APOE4,iPSC,neurons,AlphaBeta,tau phosphorylation,GABA,degeneration APOE4,iPSC,derived neurons,AlphaBeta,tau phosphorylation,GABA neuron degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration
1274	The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) carries toxic effector proteins. tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli
1395	p16INK4A accumulation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs). p16INK4A, accumulation, abnormal, wound response, microinvasive, advanced, Oral, Potentially Malignant Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, advanced, Oral, Potentially, Malignant, Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, step, advanced, Oral, Potentially, Malignant, Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, advanced, Oral, Potentially, Malignant, Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, advanced, Oral, Potentially, Malignant, Lesions, OPMLs
1273	The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly. sliding activity,kinesin-8,Kip3,bipolar spindle assembly,microtubules,cell division,Mitosis kinesin-8, Kip3, sliding activity, bipolar spindle assembly kinesin-8, Kip3, sliding activity, bipolar spindle, assembly sliding, activity, kinesin-8, protein, Kip3, promotes, bipolar, spindle, assembly kinesin-8, Kip3, sliding activity, bipolar spindle, assembly
1272	The single flash-evoked ERG b-wave is generated by activity of ON-bipolar cells. flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells
1150	Tetraspanin-3 is a causative factor in the development of acute myelogenous leukemia Tetraspanin-3, acute myelogenous leukemia, causative factor, leukemia, tetraspanins, myeloid, oncology, biomarker, cancer, hematopoietic, cell differentiation Tetraspanin-3, acute myelogenous leukemia, cancer, biomarker, signaling, protein, leukemia development Tetraspanin-3, acute myelogenous leukemia, causative factor, protein, oncology, hematopoiesis, cancer biology, immune system, cell membrane, signaling proteins Tetraspanin-3, acute myelogenous leukemia, cancer, biomarker, signaling protein, hematological malignancy, cell membrane, immune evasion, oncology, hematopoiesis Tetraspanin-3, acute myelogenous leukemia, causative factor, protein, oncology, hematopoiesis
1271	The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI. cardiac involvement, amyloidosis, late gadolinium enhancement, MRI, transmurality amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity
1270	The risk of male prisoners harming themselves is ten times that of female prisoners. male prisoners, self harm, female prisoners, risk, ratio male prisoners, self harm, female prisoners, risk factor male prisoners, self harm, female prisoners, risk factor, incarceration male prisoners, self harm, female prisoners, risk, ratio male prisoners, self harm, female prisoners, risk, incarceration
163	Bariatric surgery has a positive impact on mental health. bariatric,surgery,mental,health,impact,retrieval,obesity,psychological,benefits bariatric,surgery,mental,health,impact,obesity,psychological,wellness bariatric,surgery,mental,health,impact,retrieval,effect,obesity,psychological,support,wellness bariatric,surgery,mental,health,impact,obesity,psychological,outcomes,quality,life Bariatric,surgery,mental,health,impact,obesity,treatment,improvement,morbid,depression,benefits
1029	Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes. Regulatory T cells, Interleukin-2, Responsiveness, Autoimmune diseases, Type 1 Diabetes, Immune response regulatory T cells, interleukin-2, responsiveness, autoimmune diseases, Type 1 Diabetes, immune tolerance, cytokines, Tregs, immunosuppression interleukin-2, regulatory T cells, responsiveness, autoimmune diseases, Type 1 Diabetes, immune response, cytokines, Tregs, inflammation interleukin-2, regulatory T cells, responsiveness, autoimmune diseases, Type 1 Diabetes, immune regulation Interleukin-2, Regulatory T cells, Responsiveness, Autoimmune diseases, Type 1 Diabetes, Immune response, Inflammation, Immunotherapy, Tolerance, Cytokines
960	Polymeal nutrition reduces cardiovascular mortality. Polymeal,nutrition,cardiovascular,mortality,diet,health,polymeal diet,polymeal nutrition study Polymeal,nutrition,cardiovascular,mortality,diets,health,polymeal diet,cardiovascular disease Polymeal,nutrition,cardiovascular,mortality,diabetes,healthy,eating,habits,diets,food组合 Polymeal,nutrition,cardiovascular,mortality,diet,health,food组合 Polymeal,nutrition,cardiovascular,mortality,health,diet,effectiveness,heart,diabetes,elderly
1389	mTORC2 regulates intracellular cysteine levels through xCT inhibition. mTORC2,cysteine,xCT,regulation,intracellular,biochemistry,molecular biology,signaling pathway mTORC2,cysteine,xCT,inhibition,regulation,interncellular,metabolism mTORC2,cysteine,xCT,inhibition,regulation,internally mTORC2,cysteine,xCT,inhibition,regulation,internucleosomal degradation mTORC2,xCT,cysteine,intracellular,regulation,inhibition,biochemistry,molecularbiology,cellsignaling,proteins,metabolism
1146	Teaching hospitals do not provide better care than non-teaching hospitals. teaching hospitals, non-teaching hospitals, patient care, medical education, healthcare quality, comparative study, hospital type, clinical outcomes teaching hospitals,care quality,non-teaching hospitals,medical education,patient outcomes,hospital type,care standards teaching hospitals, care quality, non-teaching hospitals, medical education, patient outcomes teaching hospitals,care quality,non-teaching hospitals,research focus,patient outcomes,clinical training,resources分配错误，应该是：临床培训,资源 teaching hospitals,care quality,non-teaching hospitals,medical education,research institutions,patient outcomes,hospital type,evidence-based medicine
1024	Recurrent mutations occur frequently within CTCF anchor sites adjacent to oncogenes. recurrentmutations,ctcfanchorites,oncogenes,geneticvariants,molecularbiology,cancergenetics,genomics,mutationfrequency,biomarkers,transcriptionfactors recurrent,mutations,CTCF,anchor,sites,oncogenes,frequency,genetics,molecular,cancer,biology recurrentmutations,ctcfanchorites,oncogenes,molecularbiology,cancergenetics,genomicvariants,somaticmutations,geneticvariants,transcriptionfactors recurrentmutations,ctcfanchorites,oncogenes,genomicmutations,cancergenetics,molecularbiology,geneticvariants,transcriptionfactors recurrent,mutations,CTCF,anchor,sites,oncogenes,frequency,patterns,distribution,molecular,bioinformatics,gene regulation,cancer genomics,geneticvariants,genomicregions
1266	The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer. breast_cancer, parous_women, placental_weight, pregnancies, premenopausal, risk_factors breast_cancer, parous_women, placental_weight, pregnancies, premenopausal, risk_factors breast_cancer, parous_women, placental_weight, pregnancies, premenopausal, risk_factors breast_cancer, parous_women, placental_weight, pregnancies, premenopausal, risk_factors breast cancer, parous women, placental weight, pregnancies, premenopausal, risk factors
721	Lupus-prone mice infected with curliproducing bacteria have higher autoantibody titers compared to controls. Lupus, mice, curliproducing bacteria, autoantibody, titers, infection, prone Lupus, mice, autoantibodies, bacteria, curliprodution, immunity Lupus, mice, curliproducing bacteria, autoantibodies, titers, infection, lupus-prone Lupus-prone,mice,curliproducing,bacteria,autoantibody,titers,controls Lupus, mice, curliproducing bacteria, autoantibody, titers, control
1144	Taxation of sugar-sweetened beverages had no effect on the incidence rate of type II diabetes in India. taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect,retrieval_keywords taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect
723	Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions. Ly49Q, neutrophil, migration, inflammation, membrane, raft, functions Ly49Q, neutrophil, migration, inflammation, membrane raft, function Ly49Q, neutrophil, migration, inflammation, membrane, raft, functions Ly49Q, neutrophil, migration, inflammation, membrane, raft, functions Ly49Q, neutrophil, migration, inflammation, membrane, raft, functions
845	Neutrophil extracellular traps (NETs) are released by ANCA-stimulated neutrophils. Neutrophil, Extracellular, Traps, NETs, ANCA, Stimulated, Neutrophils Neutrophils, Extracellular, Traps, NETs, ANCA, Stimulated, Inflammation Neutrophil, extracellular, traps, NETs, ANCA, stimulated, neutrophils Neutrophil, Extracellular, Traps, ANCA, Stimulated, Inflammation Neutrophils, Extracellular, Traps, NETs, ANCA, Stimulated, Inflammation
967	Pretreatment with the Arp2/3 inhibitor CK-666 affects lamelliopodia formation. Pretreatment, Arp2/3, CK-666, inhibits, lamellipodia, formation Pretreatment, Arp2/3, CK-666, inhibition, lamellipodia, formation Pretreatment, Arp2/3, CK-666, inhibitory, lamellipodia, formation Pretreatment, Arp2/3, CK-666, inhibition, lamellipodia, cellmigration Pretreatment, Arp2/3, inhibitor, CK-666, lamellipodia, formation
847	New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations. tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic tissue, lesion, penetration, concentration
727	Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts. Ly6C, monocytes, inflammatory capacity, counterparts Ly6C, monocytes, inflammation, capacity, counterparts Ly6C, monocytes, inflammation, capacity, counterparts Ly6C, monocytes, inflammatory capacity, low, high, counterparts Ly6C, monocytes, inflammatory, capacity, counterparts
728	Ly6C hi monocytes have a lower inflammatory capacity than Ly6C lo monocytes. Ly6C, monocytes, inflammatory capacity, differentiation, immune response, phenotype Ly6C, monocytes, inflammatory, capacity, comparison Ly6C, monocytes, inflammatory, capacity, phenotype, differentiation Ly6C, monocytes, inflammatory, capacity, differentiation, immune, response Ly6C, monocytes, inflammatory, capacity, phenotype, comparison
729	Lymphadenopathy is observed in knockin mouse lacking the SHP-2 MAPK pathway. Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway Lymphadenopathy,knockin mouse,SHP-2,MAPK pathway Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway
1163	The DdrB protein from Deinococcus radiodurans is an alternative SSB. DdrB, protein, Deinococcus radiodurans, alternative, SSB DdrB, Deinococcus radiodurans, alternative, SSB, protein DdrB, protein, Deinococcus radiodurans, alternative, SSB, DNA repair, bacterium, radiation resistance DdrB, Deinococcus radiodurans, alternative, SSB, protein DdrB, protein, Deinococcus radiodurans, alternative, SSB
1041	Replacement of histone H2A with H2A.Z slows gene activation in yeasts by stabilizing +1 nucleosomes. histone, H2A, H2A.Z, gene, activation, yeasts, nucleosomes, stabilization histone,H2A,H2A.Z,gene activation,stable,nucleosomes,yeasts histone, H2A, H2A.Z, gene, activation, yeasts, nucleosomes, stabilization histone,H2A,H2A.Z,gene,activation,yeasts,nucleosomes,stabilizing histone,H2A,H2A.Z,geneactivation,yeasts,nucleosomes,stabilization
171	Basophils counteract disease development in patients with systemic lupus erythematosus (SLE). Basophils, Systemic Lupus Erythematosus, SLE, Disease Counteraction, Immune Response Basophils,SLE,disease counteraction,immunity,inflammation,diseases,patients Basophils, Systemic Lupus Erythematosus, SLE, immune response, inflammation, counteract, disease development Basophils, Systemic Lupus Erythematosus, Disease Counteraction, Immune Response Basophils, systemic lupus erythematosus, SLE, immune response, inflammation, counteract, disease development
1282	Therapeutic use of the drug Dapsone to treat pyoderma gangrenous is based on anecdotal evidence. Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence Dapsone, pyoderma gangrenosum, therapeutic, evidence-based, anecdotal, treatment Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence
1281	The ureABIEFGH gene cluster is induced by nickel (II) ion. ureAB gene cluster,nickel (II) ion,induction,gene regulation,microbiology,biochemistry ureAB gene cluster,nickel induction,microbiology,gene regulation,metalloregulation,Nickel(II),metal ion,expression profiling,gene expression ureABIEFGH,gene,cluster,nickel(II),ion,induction,bioavailability,metallation,transcription,regulation ureAB gene cluster,nickel induction,gene regulation,metalloregulation,microbial response,nickel ions,Gene ureAB,nickel tolerance ureAB gene cluster,nickel induction,microbiology,gene regulation,metallamacare
294	Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae. crossover,hotspots,gene,promoters,Saccharomyces,cerevisiae,molecular biology,genetics,DNA,recombination crossover, hotspots, gene, promoters, Saccharomyces cerevisiae crossover,hotspots,gene promoters,Saccharomyces cerevisiae,molecular biology,genetics,biology,DNA recombination Crossover, hotspots, gene, promoters, Saccharomyces, cerevisiae Crossover, hotspots, gene, promoters, Saccharomyces, cerevisiae
1280	The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG. ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG ureAB gene cluster, urease maturation, UreD, UreH, UreE, UreF, UreG
295	Crosstalk between dendritic cells (DCs) and innate lymphoid cells (ILCs) is important in the regulation of intestinal homeostasis. dendritic cells, innate lymphoid cells, crosstalk, intestinal homeostasis, immune regulation dendritic cells, innate lymphoid cells, crosstalk, intestinal homeostasis, immune regulation dendritic cells, innate lymphoid cells, crosstalk, intestinal homeostasis, immune regulation dendritic cells, innate lymphoid cells, crosstalk, intestinal homeostasis, immune response, immunology, inflammation, gut microbiome, cytokines, signaling pathways dendritic cells, innate lymphoid cells, intestinal homeostasis, crosstalk, immune regulation
298	Cytochrome c is released from the mitochondrial intermembrane space to cytosol during apoptosis. Cytochrome, c, mitochondria, intermembrane, space, cytosol, apoptosis, release Cytochrome, c, mitochondria, intermembrane, space, cytosol, apoptosis, release Cytochrome, c, mitochondria, intermembrane, space, cytosol, apoptosis, release Cytochrome, c, mitochondrial, intermembrane, space, cytosol, apoptosis, release Cytochrome,c,mitochondrial,intermembrane,space,cytosol,apoptosis,released
179	Birth-weight is positively associated with breast cancer. birthweight, breastcancer, positiveassociation, pregnancyoutcome, oncology, epidemiology, riskfactor birthweight, breastcancer, positiveassociation, pregnancy, offspring, oncology, epidemiology birthweight, breastcancer, positiveassociation, epidemiology, riskfactor, pregnancy, neonatology, oncology birthweight, breastcancer, positiveassociation, fetaldevelopment, oncology, epidemiology, riskfactor birthweight, breastcancer, positiveassociation, pregnancy, oncology, epidemiology, riskfactor
971	Primary cervical cancer screening with HPV detection has higher longitudinal sensitivity than conventional cytology to detect cervical intraepithelial neoplasia grade 2. cervical cancer, screening, HPV, detection, sensitivity, cytology, cervical intraepithelial neoplasia, grade 2 cervical_cancer_screening,HPV_detection,conventional_cytology,longitudinal_sensitivity,cervical_intraepithelial_neoplasia,grade_2 cervical cancer, screening, HPV, detection, sensitivity, cytology, cervical intraepithelial neoplasia, grade 2 cervical cancer, screening, HPV, detection, sensitivity, cytology, longitudinal, cervical intraepithelial neoplasia, grade 2 cervical_cancer_screening,HPV_detection,conventional_cytology,longitudinal_sensitivity,cervical_intraepithelial_neoplasia,grade_2
1279	The treatment of cancer patients with co-IR blockade precipitates adverse autoimmune events. cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR,blockade,adverse,event,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune events
1278	The treatment of cancer patients with co-IR blockade does not cause any adverse autoimmune events. cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR,blockade,adverse,autoimmune,events cancer,treatment,co-IR blockade,adverse events,autoimmune
852	Non-invasive ventilation use should be decreased if there is inadequate response to conventional treatment. non-invasive, ventilation, inadequacy, response, conventional, treatment non-invasive, ventilation, response, conventional, treatment, decrease non-invasive, ventilation, response, conventional, treatment, decrease non-invasive, ventilation, inadequate, response, conventional, treatment non-invasive, ventilation, response, conventional, treatment, decrease
975	Primary pro-inflammatory cytokines induce secondary pro- and anti-inflammatory mediators. Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory Primary,cytokines,pro-inflammatory,secondary,mediators,induce,inflammation
613	Increased microtubule acetylation repairs LRRK2 Roc-COR domain mutation induced locomotor deficits. microtubule, acetylation, LRRK2, Roc-COR, domain, locomotor, mutation, repair microtubule, acetylation, LRRK2, Roc-COR, domain, mutation, locomotor, deficits microtubule, acetylation, LRRK2, Roc-COR, domain, locomotor, mutation, repair microtubule, acetylation, LRRK2, Roc-COR, domain, locomotor, deficit, mutation microtubule, acetylation, LRRK2, Roc-COR, domain, locomotor, mutation, repair
70	Activation of PPM1D suppresses p53 function. PPM1D,p53,activation,suppression,function,molecularbiology,cancer,signaling,genetics PPM1D,p53,function,activation,inhibition,cancer,evity,pathway,molecular biology PPM1D,p53,activation,suppression,function,cancer,protein,phosphatase,molecular biology,oncology PPM1D,p53,function,activation,suppresses,cancer,protein,phosphatase,malignancy PPM1D,p53,function,activation,suppression,molecular biology,cancer research,cellular signaling,pathway regulation,gene expression,Tumor Suppressor Proteins,Thr Ser Protein Phosphatase 1 Regulatory Subunit 2
72	Activator-inhibitor pairs are provided dorsally by Admpchordin. Activator-inhibitor, pairs, Admp, chordin, dorsal, developmental biology Activator-inhibitor, pairs, Admp, chordin, dorsal, development, signaling Activator-inhibitor, pairs, Admp, chordin, dorsal, signaling, embryonic development Activator-inhibitor, pairs, Admp, chordin, dorsal, developmental biology, signaling Activator-inhibitor, pairs, Admp, chordin, dorsal, signaling, molecules
859	Normal expression of RUNX1 has tumor-promoting effects. RUNX1,tumorpromotion,normalexpression,cancerbiology,molecularmechanisms RUNX1,tumor promotion,normal expression,cancer biology,molecular mechanisms,oncology,gene function RUNX1,tumorpromotion,normalexpression,cancerbiology,molecularmechanisms RUNX1,tumor promotion,normal expression,cancer biology,molecular oncology RUNX1,tumor,promoting,expression,cancer,biochemistry,molecular biology,oncology
619	Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments. vessel,density,fibrosis,chemotherapy,efficacy,treatment vessel,density,fibrosis,chemotherapy,efficacy,reduction,increase vessel_density,fibrosis,chemotherapy,efficacy,treatment vessel_density,fibrosis,chemotherapy,efficacy,reduction,increase vessel,density,fibrosis,chemotherapy,efficacy,reduction,increased,treatment
75	Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB. H.pylori, urease, polymeric, subunits, UreA, UreB H.pylori, urease, polymeric, subunits, UreA, UreB H. pylori, urease, polymeric, subunits, UreA, UreB Active,H. pylori,urease,polymeric,subunits,UreA,UreB H. pylori, urease, polymeric, subunits, UreA, UreB
1175	The PPR MDA5 has two N-terminal CARD domains. PPR, MDA5, N-terminal, CARD, domains PPR,MDA5,N-terminal,CARD,domains PPR, MDA5, N-terminal, CARD, domains PPR,MDA5,N-terminal,CARD,domains PPR, MDA5, N-terminal, CARD, domains
180	Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 leads to increased TDP-43-induced neuronal loss. TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking
183	Bone marrow cells contribute to adult macrophage compartments. bone marrow, macrophages, adult stem cells, hematopoiesis, monocytes, myeloid lineage Bone marrow, macrophages, stem cells, hematopoiesis, adult biology, immune system bone marrow, macrophages, adult, hematopoiesis, monocytes, stem cells, immune system, regeneration bone marrow, macrophages, adult stem cells, hematopoiesis, monocytes, immune system, cell lineage, myeloid differentiation bone marrow, macrophages, adult, stem cells, hematopoiesis, immunology, regenerative medicine
1292	There is no association between HNF4A mutations and diabetes risks. HNF4A,mutations,diabetes,risk,association,gene,variant HNF4A,mutations,diabetes,risk,association,gene,disease HNF4A,mutations,diabetes,risk,association,research,genetics,biomedicine,medicine,study HNF4A,mutations,diabetes,risk,association,gene,MODY,Pancreatic,islet,cancer HNF4A,mutations,diabetes,risk,association,gene,marker,study,variant,polymorphism
185	Breast cancer development is determined exclusively by genetic factors. breast cancer, development, genetic factors, inheritance, oncology, genealogy, predisposition breast cancer, development, genetic factors, inheritance, genes, oncology, tumor, predisposition, mutations, epigenetics breast cancer, development, genetic factors, exclusivity, inheritance breast cancer, development, genetic factors, inheritance, oncogenes, tumor suppressor genes breast cancer, development, genetic factors, exclusively, determinants
1290	There is an inverse relationship between hip fractures and statin use. hip fractures, statin use, inverse relationship, bone health, cholesterol, medication, osteoporosis, epidemiology hip fractures, statin use, inverse relationship hip fractures, statin use, inverse relationship hip fractures, statin use, inverse relationship, bone health, cholesterol medication, osteoporosis prevention, geriatrics, epidemiology, pharmacotherapy hip骨折, 调血脂药, 反向关系, statin使用
1049	Ribosomopathies have a low degree of cell and tissue specific pathology. Ribosomopathies, cell specificity, tissue pathology, molecular biology, genetic disorders, ribosome function, disease mechanisms Ribosomopathies, cell specific, tissue specific, pathology, genetic, ribosomal, disorders Ribosomopathies, cell, tissue, pathology, genetic, RNA, ribosome, specificity, molecular biology, hematopoietic, disorders Ribosomopathies, cell specific pathology, tissue specific pathology, ribosome dysfunction, genetic disorders, molecular biology, pathology Ribosomopathies, cell specificity, tissue pathology, ribosomal dysfunction, genetic disorders, hematopoietic disorders, developmental defects
982	Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body. proteins,growthcone,ubiquitination,cellbody,synthesis proteins,growth cone,ubiquitination,cell body,synthesis proteins,growthcone,ubiquitination,cellbody,synthesis proteins,growthcone,ubiquitination,cellbody,synthesis Proteins,growthcone,ubiquitination,cellbody,synthesis
742	Macrolides have no protective effect against myocardial infarction. macrolides, myocardial infarction, protection, efficacy, antibiotics Macrolides, myocardial infarction, protection, clinical trial, antibiotic, cardiovascular, efficacy Macrolides, myocardial infarction, protective effect, cardiovascular, antibiotic macrolides, myocardial infarction, protective effect, cardiovascular, antibiotics macrolides, myocardial infarction, protective effect, clinical trial, antibiotics, cardiovascular disease
501	Headaches are not correlated with cognitive impairment. headaches,cognitive,impairment,correlation,retrieval,query,research,study,neurology headaches,cognitive,impairment,correlation,retrieval,query,migraines,pain,symptoms,neurology headaches,cognitive,impairment,correlation,retrieval,memory,function,neurology,pain,disease headaches,cognitive,impairment,correlation,retrieval,query,study,evidence,pain,memory,test,analysis headaches,cognitive,impairment,correlation,retrieval,query,research,medicine,neurology
743	Macrolides protect against myocardial infarction. Macrolides, myocardial infarction, antibiotics, cardiovascular, protection, treatment, mechanism, inflammation Macrolides, myocardial infarction, antibiotic, cardiovascular, protection, mechanism, clinical trial, inflammation macrolides, myocardial infarction, protection, antibiotics, cardiovascular, efficacy, mechanisms Macrolides, myocardial infarction, antibiotic, cardiovascular, protection, inflammation, mechanism, clinical trial, bacteria, immune response Macrolides, myocardial infarction, antibiotics, cardiovascular, protection, inflammation, treatment
985	Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy. pseudogene, PTENP1, regulates, expression, PTEN, miRNA, decoy pseudogene, PTENP1, PTEN, miRNA, decoy, regulation, expression pseudogene, PTENP1, PTEN, miRNA, decoy, regulation, expression pseudogene, PTENP1, PTEN, miRNA, decoy, regulation, expression pseudogene, PTENP1, PTEN, miRNA, decoy, regulation, expression
502	Healthcare delivery efficiency in crowded delivery centers is impaired by improving structural, logistical, and interpersonal elements. healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements Healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements Healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements
623	Individuals with low serum vitamin D concentrations have increased risk of multiple sclerosis. vitamin,D,serum,individuals,multiple,sclerosis,risk,concentrations vitamin,D,serum,concentrations,multiple,ms,serum,vitamin,D,risk,individuals low, serum, vitamin, D, concentrations, increased, risk, multiple, sclerosis vitamin,D,serum,concentrations,multiple,sclerosis,risk,individuals vitamin D, serum levels, multiple sclerosis, risk因素, autoimmune disease
744	Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein. macropinocytosis,amino acids,protein,intracellular uptake,cell supply Macropinocytosis,amino acids,intracellular,uptake,protein,cell Macropinocytosis,amino acids,intracellular,uptake,protein,cell Macropinocytosis,amino acids,cell uptake,protein intracellular Macropinocytosis,amino acids,cell,protein,intracellular uptake
507	Helminths interfere with immune system control of macrophages activated by IL-4 favor Mycobacterium tuberculosis replication. helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, immunity, pathogen, host, inflammation, cytokines, parasite, bacteria helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, cytokine, immunity, parasitic worms, bacterial replication, host response Helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, immunity, parasite, host response, cytokines, inflammation, pathology Helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, immunology, parasitology, pathogenesis helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, immunity, parasitic worms, cytokines, inflammation, pathogeninteraction
628	Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of African origin. infection,T-cell,lymphotropic,virus,African,origin,Human,T-cell_lymphotropic_virus_type_1 Infection, human, T-cell, lymphotropic, virus, type, 1, African, origin Infection,T-cell,lymphotropic,virus,African,origin,HIV-1 Infection,African,origin,human,T-cell,lymphotropic,virus,HTLV-1 Infection,T-cell,lymphotropic,virus,African,origin,human
508	Hematopoietic Stem Cell purification reaches purity rate of up to 50%. Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biotechnology, Isolation, Technique, Hematology Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biotechnology, Isolation, Technique Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biotechnology, Isolation, Technique, Transplantation, Cancer, Therapy Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biotechnology, Isolation, Technique Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biotechnology, Isolation, Technique
1187	The YAP1 and TEAD complex tanslocates into the nucleus where it interacts with transcription factors and DNA-binding proteins that modulate target gene transcription. YAP1, TEAD, nuclear translocation, transcription factors, DNA-binding proteins, gene transcription YAP1, TEAD, nucleus, transcription, factors, DNA-binding, proteins, gene, modulation YAP1, TEAD, nucleus, transcription, factors, DNA-binding, proteins, target, gene, modulation YAP1, TEAD, nucleus, transcription, factors, DNA-binding, proteins, gene, modulation YAP1, TEAD, nuclear translocation, transcription factors, DNA-binding proteins, target gene transcription
1185	The US health care system can save up to $750 million if 7% of patients waiting for kidney transplants participate in the optimized national kidney paired donation program. US, health care, system, save, cost, patients, kidney, transplants, optimized, national, program, donation, paired US,health care,system,save,costs,kidney,transplants,participate,optimized,national,kidney,paired,donation,program,waiting,patients,improve,retrieval,$750,million,%7 US, health care, system, savings, $750 million, 7%, patients, kidney, transplants, optimized, national, kidney paired donation, program US, health care, savings, kidney transplants, optimized, national kidney paired donation program, participation US,health care,system,savings,kidney,transplants,optimized,national,kidney,paired,donation,program,patients,%7,improve,retrieval
1062	S-nitrosylated GAPDH physiologically transnitrosylates histone deacetylases. S-nitrosylation,GAPDH,transnitrosylation,histone deacetylases,physiology S-nitrosylation,GAPDH,transnitrosylation,histone deacetylases,physiology S-nitrosylation,GAPDH,transnitrosylation,histone deacetylases,physiology,nitricoxide S-nitrosylation,GAPDH,histone deacetylases,physiological,nitrosylation,protein modification,enzymes,histones,posttranslational modification,nitricoxide S-nitrosylation,GAPDH,histone deacetylases,physiological,nitrosylation
1180	The PRR MDA5 is a sensor of RNA virus infection. PRR, MDA5, RNA, virus, infection, innate, immunity, sensor PRR, MDA5, RNA, virus, infection, sensor PRR, MDA5, RNA, virus, infection, innate, immunity PRR, MDA5, RNA, virus, infection, sensor PRR, MDA5, RNA, virus, infection, sensor
198	CCL19 is absent within dLNs. CCL19, dLNs, lymph nodes, immunology, lymphatic system, chemokines, inflammation CCL19, dLNs, lymph nodes, immune response, chemokine, immunology CCL19, dLNs, lymph nodes, absence, chemokine, immune response CCL19, dLNs, lymph node, immunology, absence, chemokine, immune response CCL19, dLNs, dendritic, lymph nodes, absence, chemokine
870	Obesity decreases life quality. obesity, life, quality, health, impact, overweight, mortality, nutrition, fitness, complications obesity, life quality, health, mortality, weight, BMI, obesity-related, lifespan, overweight, fatness obesity, life, quality, health, impact, obesity-related, lifespan, well-being, overweight, fatness obesity, life, quality, health, impact, weight, obesity-related, mortality, wellbeing, obesity-complications obesity, life quality, health, mortality, weight, BMI, metabolic, disorders, complications, longevity
993	Pyridostatin destabilizes the G - quadruplex in the telomeric region. Pyridostatin,G-quadruplex,telomeric region,DNA,stabilization,biology,molecular biology,rNA interference Pyridostatin,G-quadruplex,telomeric region,DNA stability,telomeres,biochemistry,molecular biology,nucleic acids,RNA interference Pyridostatin,G-quadruplex,telomeric region,DNA,structure,stability,binding,molecular biology,cancer therapy,antitumor activity Pyridostatin,telomeric region,G-quadruplex,stabilization,retention,molecular biology,DNA structure Pyridostatin,G-quadruplex,telomeric,region,stabilization,dNA,molecular,binding,potential,cancer,therapy
873	Obesity is determined solely by environmental factors. obesity, environmental, factors, genetics, diet, lifestyle, metabolism, socioeconomic, influences, epidemiology obesity, environmental, factors, genetics, lifestyle, diet, metabolism obesity, environmental factors, genetics, lifestyle, nutrition, metabolism, socioeconomic status, physical activity obesity, environmental, factors, genetics, lifestyle, nutrition, metabolism, health, epidemic, socioeconomic, intervention obesity, environmental, factors, genetics, diet, lifestyle, metabolism
1179	The PRR MDA5 has a central DExD/H RNA helices domain. PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain
1298	Thigh-length graduated compression stockings (GCS) did not reduce deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke. thigh-length, graduated, compression, stockings, deep, vein, thrombosis, patients, hospitalized, immobile, acute, stroke thigh-length,gcs,graduatedcompressionstockings,deepveinthrombosis,immobile,acutestroke,hospital,reduction,treatment,effectiveness,preventive措施 thigh-length, graduated, compression, stockings, deep, vein, thrombosis, patients, immobile, acute, stroke, hospital compression, stockings, deep, vein, thrombosis, patients, immobile, acute, stroke, hospital thigh-length, graduated, compression, stockings, GCS, deep, vein, thrombosis, patients, immobile, acute, stroke, hospital
513	High cardiopulmonary fitness causes increased mortality rate. cardiovascular, pulmonary, fitness, mortality, exercise, endurance, health, risk, survival, sports, physical activity cardiopulmonary,fitness,mortality,risk,factors,health,outcomes cardiopulmonary, fitness, mortality, rate, high, correlation, study, research, exercise, endurance cardiopulmonary, fitness, mortality, rate, high, correlation, study, research, cardiovascular, pulmonary, health, longevity cardiopulmonary, fitness, mortality, rate, high, correlation, health, exercise, endurance
514	High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter. calcium intake, secondary hyperparathyroidism, 25(OH)D, vitamin D, prevention, subjects calcium, diet, hyperparathyroidism, 25(OH)D, vitamin D, prevention, nutrition, supplementation calcium, intake, prevention, secondary, hyperparathyroidism, 25(OH)D, levels, subjects, vitamin D, nutrition, health calcium intake, hyperparathyroidism, vitamin D, 25(OH)D, prevention dietary calcium, hyperparathyroidism, 25(OH)D, vitamin D, secondary hyperparathyroidism, calcium intake
756	Many proteins in human cells can be post-translationally modified at lysine residues via acetylation. proteins, human cells, post-translational modification, lysine residues, acetylation proteins, human cells, post-translational modification, lysine, acetylation proteins, human cells, post-translational modification, lysine, acetylation proteins, human cells, post-translational modification, lysine residues, acetylation proteins, human cells, post-translational modification, lysine, acetylation
636	Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate. PTEN,inositol,lipid,phosphatase,Ptdlns(3,4)P,2,phosphatidylinositol,4-phosphate PTEN,inositol,lipid,3-phosphatase,Ptdlns(3,4)P2,phosphatidylinositol,4-phosphate PTEN,inositol,lipid,phosphatase,Ptdlns(3,4)P2,phosphatidylinositol,4-phosphate PTEN,inositol,lipid,3-phosphatase,Ptdlns(3,4)P2,phosphatidylinositol,4-phosphate PTEN,inositol,lipid,phosphatase,Ptdlns(3,4)P,2,phosphatidylinositol,4-phosphate
516	High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD). CRP,COPD,exacerbations,risk,high levels,pulmonary disease CRP,COPD,exacerbations,risk,factors CRP, COPD, exacerbations, risk, inflammation CRP, COPD, exacerbations, inflammation, risk, levels CRP,COPD,exacerbations,risk,chronic obstructive pulmonary disease,inflammation
637	Input from  mental and physical health care professionals is effective at decreasing homelessness. input,mental,physical,healthcare,professionals,effective,decreasing,homelessness,retrieval,keywords mental-health, physical-health, healthcare-professionals, homelessness, input, effectiveness, interventions, support, services, policy, prevention, treatment, collaboration mentalhealth, physicalhealth, healthcareprofessionals, homelessness, inputeffectiveness mentalhealth, physicalhealth, healthcareprofessionals, homelessness, input, effectiveness, interventions, support, services, policy, outcomes mentalhealth, physicalhealth, healthcareprofessionals, homelessness, input, effectiveness
879	Occupancy of ribosomes by IncRNAs do not make functional peptides. ribosomes, IncRNAs, occupancy, functional, peptides ribosomes, IncRNAs, occupancy, functional, peptides ribosomes, IncRNAs, occupancy, functional, peptides ribosomes, IncRNAs, occupancy, functional, peptides ribosomes, IncRNAs, occupancy, functional, peptides
517	High levels of copeptin decrease risk of diabetes. copeptin, diabetes, risk, high, levels copeptin, diabetes, risk, high, levels copeptin, diabetes, risk, levels, hormone copeptin, diabetes, risk, high, levels copeptin, diabetes, risk, high, levels
759	Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have a dramatic impact in reducing malaria transmission. mathematical models, artemisinin-based combination therapy, nongametocytocidal drugs, malaria transmission, impact reduction Mathematical models,malaria transmission,Artemisinin-based combination therapy,nongametocytocidal drugs,predictions mathematical, models, artemisinin, combination, therapy, nongametocytocidal, drugs, malaria, transmission, reduce, impact mathematical, models, artemisinin, combination, therapy, nongametocytocidal, drugs, malaria, transmission, impact mathematical, models, artemisinin, combination, therapy, nongametocytocidal, drugs, malaria, transmission
94	Albendazole is used to treat lymphatic filariasis. Albendazole, lymphatic filariasis, treatment, drug, parasite, infection, medicine albendazole, lymphatic, filariasis, treatment, drug, parasitic, infection albendazole, lymphatic, filariasis, treatment, drug, parasitic, infection albendazole, lymphatic, filariasis, treatment, drug albendazole, lymphatic, filariasis, treatment, medication, parasitic, infection
99	Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding. Alizarin,hydrogen bonds,PGAM1,substrate binding,residues Alizarin,Hydrogen bonds,PGAM1,Substrate binding,residues Alizarin,hydrogen bonds,PGAM1,substrate binding,residues Alizarin,Hydrogen bonds,PGAM1,Substrate binding,Amino acid residues Alizarin,hydrogen bonds,PGAM1,substrate binding,residues
1197	The availability of safe places to study is not effective at decreasing homelessness. safe study spaces, homelessness, effectiveness, housing, resources, education, urban areas, policies, accessibility study_spaces,safe_places,homelessness,effectiveness,availability,retrieval_keywords safe study spaces, homelessness, availability, effectiveness, housing, education, resources, urban areas, poverty, policies safe places, study locations, homelessness, effectiveness, availability, housing options, educational resources, shelter, impact analysis safe places, study areas, homelessness, effectiveness, availability, housing, resources, education, shelter, policies, urbanareas, sociology, demographics, socialwork
1196	The availability of safe places to study is effective at decreasing homelessness. safe study spaces, homelessness prevention, educational accessibility, housing solutions, community resources, learning environments, shelter options, academic support, urban planning, social impact safe study spaces, homelessness prevention, educational access, housing stability, community resources study spaces,safe places,homelessness,effectiveness,availability,resources safe study spaces, homelessness prevention, educational resources, housing stability, community centers, shelter access, learning environments, poverty reduction, social services, urban planning safe study spaces, homelessness prevention, educational environments, housing stability, urban planning, community resources, student well-being
1194	The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'. TatAd, complexes, arm, density, structural, rearrangements, Class1, charge, zipper, mechanism TatAd, complexes, arm density, structural rearrangements, Class1, charge zipper mechanism TatAd, complexes, arm, density, structural, rearrangements, Class1, charge, zipper, mechanism TatAd, complexes, arm, density, structural, rearrangements, Class1, charge, zipper, mechanism TatAd, complexes, arm density, structural rearrangements, Class1, charge zipper mechanism
1191	The amount of publicly available DNA data doubles every 10 years. DNA, data, doubling, public, decade, genetics DNA, data, doubling, trend, genetics, bioinformatics, storage, public, genome DNA, data, doubling, time, public, availability DNA, data, doubling, public, decade, genetic, information DNA, data, doubling, time, public, genetic, information
880	Occupancy of ribosomes by IncRNAs mirror 5 0-UTRs Ribosomes, IncRNAs, 5'UTRs, Occupancy, mRNA, Regulation, Biology, Translation ribosomes, IncRNAs, occupancy, 5_utrs, mirroring ribosomes, IncRNAs, 5'UTRs, occupancy, mirror, RNA, translation, regulation ribosomes, IncRNAs, 5',UTRs, occupancy, mirror, RNA, translation ribosomes, IncRNAs, occupancy, 5, UTRs, mirror, RNA, biology, translation
882	Omnivores produce less trimethylamine N-oxide from dietary I-carnitine than vegetarians. omnivores,trimethylamine N-oxide,I-carnitine,vegetarians,dietary,production omnivores,trimethylamine N-oxide,I-carnitine,vegetarians,dietary,production Omnivores, trimethylamine, N-oxide, I-carnitine, vegetarians omnivores, trimethylamine, N-oxide, dietary, I-carnitine, vegetarians Omnivores, vegetarians, trimethylamine, N-oxide, dietary, I-carnitine
641	Insomnia can be effectively treated with cognitive behavioral therapy. insomnia,cognitive,behavioral,therapy,treatment,sleep,disorder,mental,health insomnia,cognitive,behavioral,therapy,treatment,sleep,disorders,mind,body,habits insomnia,cognitive,behavioral,therapy,treatment,sleep,disorder,mental,health insomnia,cognitive,behavioral,therapy,treatment,sleep,disorder,mind,body,interventions,psychology insomnia,cognitive,behavioral,therapy,treatment,sleep,disorder,psychology,health,mind,body
521	High-sensitivity cardiac troponin T (HSCT-T) dosage may not be diagnostic if the onset of symptoms occurs less than 3 hours before acute myocardial injury (AMI). High-sensitivity, cardiac,troponin,T,HSCT-T,dosage,symptoms,onset,acute,myocardial,injury,AMI,timeeliness,testing,diagnosis HSCT-T,dosage,diagnostic,onset,symptoms,acute myocardial injury,time window high-sensitivity, cardiac, troponin, T, HSCT-T, dosage, symptom, onset, acute, myocardial, injury, AMI, diagnosis, time High-sensitivity, cardiac,troponin,T,HSCT-T,dosage,symptoms,onset,acute,myocardial,injury,AMI,time,diagnostic High-sensitivity, cardiac,troponin,T,HSCT-T,dosage,symptoms,onset,acute,myocardial,injury,AMI,time窗限,3hours
644	Insulin increases risk of severe kidney failure. insulin,kidney,failure,risk,severe insulin,kidney,failure,risk,severe insulin,kidney,failure,risk,severe,disease,endocrine,diabetes insulin,kidney,failure,risk,end-stage,renal,disease,diabetes,mellitus,glucose,glycemic,control,diabetic,nephropathy insulin,kidney failure,risk,failure,severe,diabetes mellitus,end-stage renal disease,EPS
887	Only a minority of cells survive development after differentiation into stress-resistant spores. minority, cells, survive, development, differentiation, stress-resistant, spores minority,cells,survive,development,differentiation,stress-resistant,spores minority,cells,survive,development,differentiation,stress-resistant,spores minority,cells,survive,development,differentiation,stress-resistant,spores survival, cells, minority, development, differentiation, stress-resistant, spores
525	Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors. Histone,demethylase,recruitment,methylation,nuclear,receptors,transcription,ligand,induction,temporary Histone demethylase, recruitment, transient, histone methylation, ligand-dependent, induction, transcription, nuclear receptors Histone,demethylase,recruitment,methylation,nuclear,receptors,transcription,ligand,induction,temporary Histone,demethylase,recruitment,methylation,nuclear,receptors,transcription,ligand,induction,temporary Histone demethylase, nuclear receptors, transcription, ligand-dependent, histone methylation, recruitment, decrease
768	Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT). Mercaptopurine,methylmercaptopurine,thiopurine,methyltrasnferase,tpmt,anabolism Mercaptopurine,methylmercaptopurine,thiopurine methyltrasnferase,tpmt,anabolized,inactive Mercaptopurine,methylmercaptopurine,thiopurine,methyltrasnferase,TPMT,isobutylmercaptopurine,metabolism,anabolism Mercaptopurine, anabolized, methylmercaptopurine, thiopurine, methyltransferase, TPMT Mercaptopurine, anabolized, methylmercaptopurine, thiopurine, methyltransferase, TPMT
527	Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress. Homozygous, deletion, murine, Sbds, gene, osterix, expressing, mesenchymal, stem, progenitor, cells, MPCs, prevents, oxidative, stress Homozygous deletion, murine Sbds gene, osterix-expressing, mesenchymal stem cells, progenitor cells, MPCs, oxidative stress Homozygous, deletion, murine, Sbds, gene, osterix, expressing, mesenchymal, stem, progenitor, cells, MPCs, prevents, oxidative, stress Homozygous, deletion, murine, Sbds, gene, osterix, expressing, mesenchymal, stem, progenitor, cells, MPCs, prevents, oxidative, stress Homozygous deletion,murine,Sbds gene,osteix-expressing,mesenchymal stem,progenitor cells,MPCs,prevents,oxidative stress
528	Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) patients produce Immunoglobulin G (IgG) antibodies which cross-react with an immunodominant epitope in Tax. Human,T-lymphotropic,virus,Type-I,associated,myelopathy,tropical,spastic,paraparesis,HAM/TSP,Immunoglobulin,G,IgG,antibodies,immunodominant,epitope,Tax Human T-lymphotropic virus, type-I, HAM/TSP, patients, Immunoglobulin G, antibodies, cross-react, Tax, immunodominant epitope Human T-lymphotropic virus, type-I, HAM/TSP, patients, Immunoglobulin G, antibodies, cross-react, immunodominant epitope, Tax Human,T-lymphotropic,virus,Type-I,associated,myelopathy,tropical,spastic,paraparesis,HAM/TSP,Immunoglobulin,G,IgG,antibodies,epitope,Tax Human,T-lymphotropic,virus,Type-I,associated,myelopathy,tropical,spastic,paraparesis,HAM/TSP,Immunoglobulin,G,IgG,antibodies,epitope,Tax
649	Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance classroom, collaborative, learning, web-based, integration, performance, subpar classroom learning, web-based learning, collaborative learning, class performance, integration, technology, education, effectiveness, online collaboration, face-to-face collaboration classroom, collaborative, learning, web-based, performance, integration, effectiveness, technology, education, students, interaction, online, hybrid classroom, collaborative, learning, web-based, performance, integration, effectiveness, education, technology, blended, methods classroom learning, web-based learning, collaborative learning, performance, integration, effectiveness, education, technology, online learning, blended learning
1088	Silencing of Bcl2 is important for the maintenance and progression of tumors. Bcl2,silencing,tumors,maintenance,progression,oncology,cancertherapy,geneexpression,molecularbiology,nanotechnology,apoptosis,chemotherapy,resistance Bcl2,silencing,tumors,maintenance,progression,cancer biology,apoptosis,genetic regulation,'oncotherapy Bcl2,silencing,tumors,maintenance,progression,cancer,apoptosis,molecular biology,oncology Bcl2,silencing,tumors,maintenance,progression,cancer biology,apoptosis,genetic regulation,molecular biology,oncology Bcl2,silencing,tumors,maintenance,progression,oncology,cancer biology,apoptosis,proliferation,therapy,resistance
1086	Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants. sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction Sildenafil, erectile function, SSRI, antidepressants, sexual dysfunction Sildenafil, erectile function, SSRI, antidepressants, sexual dysfunction sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction
770	Metastatic colorectal cancer treated with a single agent fluoropyrimidines resulted in reduced efficacy and lower quality of life when compared with oxaliplatin-based chemotherapy in elderly patients. metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,efficacy,quality,life,chemotherapy Metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,efficacy,quality,life metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,efficacy,quality,life metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,efficacy,quality_of_life metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,efficacy,quality,life,chemotherapy
410	Febrile seizures increase the threshold for development of epilepsy. febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase
411	Febrile seizures reduce the threshold for development of epilepsy. febrile seizures, epilepsy, seizure threshold, brain, neurons, pediatric, fever, risk factor, neurology febrile seizures, epilepsy, neuronal excitability, fever, brain development, seizure threshold, pediatric epilepsy febrile seizures, epilepsy, seizure threshold, developmental epilepsy, fever, brain function, neurological disorders, childhood seizures febrile seizures, epilepsy, seizure threshold, neurological disorders, pediatric seizures febrile seizures, epilepsy, threshold, development, reduce
532	Hyperfibrinogenemia decreases rates of femoropopliteal bypass thrombosis. Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,fibrinogen Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,improvement,retention,rates,fibrinogen Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,fibrinogen Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,fibrinogen
533	Hyperfibrinogenemia increases rates of femoropopliteal bypass thrombosis. Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,increase,vascular,condition,clotting,hypercoagulability Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,increase Hyperfibrinogenemia, femoropopliteal, bypass, thrombosis, vascular, surgery, blood, clotting, factor, genetics, risk, treatment, prevention Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,increase,fibrinogen
775	Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) reveal increased sensitivity to ionizing radiation (IR). mice,DNA,polymerase,defective,sensitivity/ionizing,radiation mice,DNA,polymerase I,polI,sensitivity/ionizing radiation,IR mice,DNA,polymerase,IR,sensitivity,damage,retrieval,molecular,biochemistry,genetics,radiation,resistance mice,DNA,polymerase,defective,ionizing,radiation,sensitivity mice,DNA,polymerase I,defective,sensitivity/ionizing radiation
1199	The benefits of colchicine were achieved with effective widespread use of secondary prevention strategies such as high-dose statins. colchicine,benefits,secondary prevention,strategies,high-dose statins,widespread use colchicine,benefits,secondary prevention,strategies,high-dose statins,widespread use colchicine, benefits, secondary, prevention, strategies, high-dose, statins colchicine,benefits,secondary prevention,strategies,high-dose statins,widespread use colchicine,benefits,secondary prevention,strategies,high-dose statins,widespread use
535	Hypertension is frequently observed in type 1 diabetes patients. Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed
415	Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia. ApoE4, APOE4, female, dementia, risk, carriers, Alzheimer, genetics Apolipoprotein E4,APOE4,female,dementia,risk,carrier,genetic,predisposition ApoE4, APOE4, female, dementia, carriers, genetic, risk Apolipoprotein E4,female,dementia,risk,carrier,allele ApoE4, APOE4, female, carriers, dementia, Alzheimer, risk
536	Hypocretin neurones induce panicprone state in rats. Hypocretin, Neurones, Panicprone, Rats, Anxiety, Hypocretinergic, System, Stress, Behavior, Neurotransmitter Hypocretin, Neurones, Panic, Rats, Neurotransmitter, Behavior, Anxiety Hypocretin, neurones, panicprone, rats, neurobiology, anxiety, sleep, hypocretinomas, orexin, neurotransmitters Hypocretin, Neurones, Panicprone, Rats, Neuroscience, Anxiety, Behavior, Physiology Hypocretin, Neurones, Panicprone, Rats, Neuroscience, Behavior, Stress, Sleep, Disorders
659	Ivermectin is used to treat lymphatic filariasis. Ivermectin, lymphatic, filariasis, treatment Ivermectin, lymphatic, filariasis, treatment Ivermectin, lymphatic, filariasis, treatment Ivermectin, lymphatic, filariasis, treatment Ivermectin, lymphatic, filariasis, treatment
539	Hypoglycemia increases the risk of dementia. hypoglycemia,dementia,risk,factors,diabetes,glycemic control,brain health hypoglycemia,dementia,risk,factors,glucose,memory,brain,age,diabetes,neurodegeneration Hypoglycemia,dementia,risk,factors,glucose,neurodegeneration,elderly,diabetes Hypoglycemia,dementia,risk,factors,diabetes,memory,impairment,glucose,nursing,seniors hypoglycemia,dementia,risk,factors,glucose,memory,neurodegeneration,endocrinology,diabetes
1099	Statins decrease blood cholesterol. statins, cholesterol, blood, lipid, reduction, medication, heart, health, treatment statins, cholesterol, blood, lipid, medication, treatment, heart, health statins, cholesterol, blood, medication, lowering, heart disease, treatment statins, cholesterol, blood, lowering, medication, heart, health statins, cholesterol, blood, lipid, medication, treatment, heart, health
660	Ivermectin is used to treat onchocerciasis. Ivermectin,onchocerciasis,treatment,disease,medicine_antiparasitic Ivermectin,onchocerciasis,treatment,drug,medication Ivermectin,onchocerciasis,treatment,medication,disease,filariasis Ivermectin,onchocerciasis,treatment,medicine,anti-parasitic Ivermectin,onchocerciasis,treatment,medicine,anti-parasitic
781	Mice that lack Interferon-γ or its receptor exhibit high resistance to experimental autoimmune myocarditis. Mice, Interferon-γ, receptor, experimental autoimmune myocarditis, resistance Mice, Interferon-γ, receptor, experimental, autoimmune, myocarditis, resistance Mice, Interferon-γ, receptor, experimental autoimmune myocarditis, resistance Mice, Interferon-γ, receptor, experimental, autoimmune, myocarditis, resistance Mice, Interferon-γ, receptor, experimental, autoimmune, myocarditis, resistance
540	Hypothalamic glutamate neurotransmission is crucial to energy balance. Hypothalamus, glutamate, neurotransmission, energy, balance Hypothalamus, glutamate, neurotransmission, energy, balance Hypothalamus, glutamate, neurotransmission, energy, balance Hypothalamus, glutamate, neurotransmission, energy, balance hypothalamus, glutamate, neurotransmission, energy, balance
783	Mice without IFN-γ or its receptor are resistant to EAM induced with α-MyHC/CFA. Mice,IFN-γ,receptor,EAM,α-MyHC,CFA,resistance Mice, IFN-γ, receptor, EAM, α-MyHC, CFA, resistance Mice, IFN-γ, receptor, EAM, α-MyHC/CFA, resistance Mice, IFN-γ, receptor, EAM, α-MyHC/CFA, resistance Mice, IFN-γ, receptor, EAM, α-MyHC/CFA, resistance
300	Cytosolic proteins bind to iron-responsive elements on mRNAs coding for DMT1. Cytosolic proteins bind to iron-responsive elements on mRNAs coding for proteins involved in iron uptake. Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake
421	Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules. flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules,diffusion,size,shape,interactions,biomolecules,pores,cavities flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules,diffusion,size,effect,environmental,constraints flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules,binding,affinity,size,effectiveness flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules,diffusion,size,interaction flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules,diffusion,size,effectiveness
784	MicroRNA is involved in the regulation of Neural Stem Cell (NSC) differentiation and proliferation dynamic homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis
785	Microarray results from culture-amplified mixtures of serotypes correlate poorly with microarray results from uncultured mixtures. microarray, serotypes, culture-amplified, uncultured, correlation, mixtures microarray, culture-amplified, serotypes, correlation, uncultured, mixtures microarray,culture,serotypes,mixtures,uncultured,correlation microarray, culture, serotypes, correlation, uncultured, mixtures microarray,culture,serotypes,mixture,uncultured,correlation
544	IFIT1 restricts viral replication by sequestrating mis-capped viral RNAs. IFIT1,viral replication,mis-capped viral RNAs,sequestration IFIT1,viral replication,mis-capped,RNA,sequestration,Virus:host interaction,Viral RNA processing,Virus defense机制,Virus entry阻断 IFIT1,viral replication,mis-capped,RNAs,sequestration,virusdefense,antiviral,biologicalprocess,immunology,virology,molecularbiology,RNAprocessing IFIT1,viral replication,mis-capped,RNAs,sequestration,virus IFIT1,viral replication,mis-capped,viral RNAs,sequestration
303	DMRT1 is a sex-determining gene that is epigenetically regulated by the MHM region. DMRT1, sex determination, epigenetics, MHM region DMRT1, sex-determining, gene, epigenetic, regulation, MHM, region DMRT1, sex-determination, epigenetics, MHM, gene regulation DMRT1, sex determination, epigenetics, MHM region, gene regulation DMRT1, sex determination, epigenetics, MHM region
1089	Smc5/6 engagment drives the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding. Smc5/6, SUMO, E3 ligase, Mms21, ATP, remodeling, chromatin, SUMOylation Smc5/6, SUMO, E3 ligase, Mms21, ATP, remolding, chromatin, cell division, protein modification, DNA repair Smc5/6, SUMOylation, Mms21, ATP, E3 ligase, chromatin, remodeling, cell cycle, DNA repair Smc5/6, SUMO, E3 ligase, Mms21, ATP, remodeling, chromatin, SUMOylation Smc5/6, SUMO, E3 ligase, Mms21, ATP, remolding, chromatin, SUMOylation
549	IRG1 has antiviral effects against neurotropic viruses. IRG1, antiviral, neurotropic, viruses, immune response, protein, interferon, gene, infection IRG1, antiviral, neurotropic, viruses, protein, interferon, response, infection, protection, biology, immunity IRG1, antiviral, neurotropic, viruses, immune, response, protein IRG1, antiviral, neurotropic, viruses, immune, response, mechanism IRG1, antiviral, neurotropic, viruses, immune response, protein, protection, infection
551	ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR). ITAM,phosphorylation,TCR,T-cell,receptor,signal,transfer,echo-domain,cytoplasmic,tail ITAM,phosphorylation,TCR,T-cell,echo-domain,cytoplasmic,signal,transduction ITAM, phosphorylation, TCR, echo-domain, cytoplasmic, signal transduction ITAM, phosphorylation, TCR, echo-domain, cytoplasmic, signal, transfer ITAM,phosphorylation,TCR,echo-domain,cytoplasmic,tail,signal,trasfer,T cell receptor
793	Mitochondria are uninvolved in apoptosis. mitochondria, apoptosis, involvement, cell death, mitochondrial, biology, science, research, genetics, biochemistry mitochondria, apoptosis, involvement, cell death, organelle mitochondria, apoptosis, involvement, cell death, biochemistry, mitochondria function, programmed cell death mitochondria, apoptosis, involvement, cell death, mitochondrial, regulation mitochondria, apoptosis, involvement, cellular, biology, function
431	FoxO3a activation in neuronal death is mediated by reactive oxygen species (ROS). FoxO3a, neuronal death, reactive oxygen species, ROS, activation FoxO3a, neuronal death, reactive oxygen species, ROS, activation, mediation FoxO3a, neuronal death, reactive oxygen species, ROS, activation FoxO3a, neuronal death, reactive oxygen species, ROS, activation FoxO3a, neuronal death, reactive oxygen species, ROS, activation
552	IgA plasma cells that are specific for transglutaminase 2 accumulate in the duodenal mucosa on commencement of a gluten-free diet. IgA, plasma, cells, transglutaminase, 2, accumulate, duodenal, mucosa, gluten-free, diet IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet, accumulation IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet, accumulation IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet, accumulation IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet, accumulation
674	LDL cholesterol has no involvement in the development of cardiovascular disease. LDL, cholesterol, cardiovascular, disease, involvement, metabolic, genetics, lifestyle, inflammation LDL, cholesterol, cardiovascular, disease, involvement, mechanism LDL, cholesterol, cardiovascular, disease, involvement, metabolic, genetics, lifestyle, inflammation, atherosclerosis LDL, cholesterol, cardiovascular, disease, involvement, metabolism, atherosclerosis LDL, cholesterol, cardiovascular, disease, involvement, metabolism
312	De novo assembly of sequence data has more specific contigs than unassembled sequence data. de novo, assembly, sequence, data, contigs, unassembled de novo assembly, contigs, unassembled sequence data, specificity de novo assembly, contigs, unassembled sequence data, specificity de novo, assembly, contigs, unassembled, sequence data, specificity de novo assembly, contigs, unassembled sequence data, bioinformatics, genome assembly, sequencing technologies
554	Immune complex triggered cell death leads to extracellular release of neutrophil protein HMGB1. immune complexes, cell death, extracellular, neutrophil, HMGB1 immune complexes, cell death, extracellular, neutrophil, HMGB1, protein immune complex, cell death, extracellular, neutrophil, HMGB1 immune complexes, cell death, extracellular, neutrophil, HMGB1, protein immune complexes, cell death, extracellular release, neutrophils, HMGB1
314	Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome. deamination, cytidine, uridine, minus strand, viral DNA, G-to-A mutations, genome deamination, cytidine, uridine, viral DNA, minus strand, G-to-A mutations, genome deamination,cytidine,uridine,viral DNA,minus strand,G-to-A mutations,catastrophic deamination, cytidine, uridine, viral DNA, minus strand, G-to-A mutations, genome deamination, cytidine, uridine, minus strand, viral DNA, G-to-A mutations, genome
436	Free histones are degraded by a Rad53-dependent mechanism once DNA has been replicated. free histones, Rad53, DNA replication, degradation, mechanism Free histones, Rad53-dependent, DNA replication, degradation free histones, degradation, Rad53, DNA replication, mechanism free histones, Rad53, DNA replication, degradation, mechanism Free histones, Rad53, DNA replication, degradation, mechanism
437	Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model. functional consequences, genomic alterations, Myelodysplastic syndrome, MDS, animal model, understanding, biological impact, hematopoietic disorders functional consequences, genomic alterations, Myelodysplastic syndrome, MDS, animal model, understanding, biomedical research genomic alterations, Myelodysplastic syndrome, functional consequences, animal models, understanding functional consequences, genomic alterations, Myelodysplastic syndrome, MDS, animal model, understanding, biological impact, hematopoiesis, genetic mutations, disease modeling, stem cells, blood disorders functional consequences, genomic alterations, Myelodysplastic syndrome, MDS, animal model, understanding, biological impact
439	Fz/PCP-dependent Pk localizes to the anterior membrane of neuroectoderm cells during zebrafish neuralation Fz/PCP, PK, zebrafish, neuroectoderm, neuralation, anterior membrane Fz/PCP, Pk, anterior membrane, neuroectoderm, zebrafish, neuralation Fz/PCP, PK, zebrafish, neuroectoderm, neuralation, anterior membrane, localization Fz/PCP, Pk, localization, anterior membrane, neuroectoderm, zebrafish, neuralation Fz/PCP, Pk, localization, anterior membrane, neuroectoderm, zebrafish, neuralation
560	Immune responses result in the development of inflammatory Th17 cells and anti-inflammatory iTregs. Immune responses,Th17 cells,iTregs,inflammation,regulatory T cells,anti-inflammatory Immune responses,Th17 cells,iTregs,inflammation,regulatory T cells,T helper cells immune responses, Th17 cells, iTregs, inflammation immune responses, Th17 cells, iTregs, inflammation, regulatory T cells immune responses, Th17 cells, iTregs, inflammation, immune system
440	Fz/PCP-dependent Pk localizes to the anterior membrane of notochord cells during zebrafish neuralation. Fz/PCP, Pk, notochord, zebrafish, neuralation, anterior membrane Fz/PCP, Pk, notochord, zebrafish, neuralation, anterior membrane Fz/PCP, Pk, localization, anterior membrane, notochord cells, zebrafish, neuralation Fz/PCP, Pk, notochord, zebrafish, neuralation, anterior membrane Fz/PCP, PK, zebrafish, neuralation, notochord, anterior membrane
1303	Tirasemtiv has no effect on fast-twitch muscle. tirasemtiv, fast-twitch, muscle, efficacy, neurological, treatment, clinical, trial, study tirasemtiv, fast-twitch, muscle, efficacy, no effect tirasemtiv, fast-twitch, muscle, effect, neurodegenerative, disease, clinical, trial, neuroscience tirasemtiv, fast-twitch, muscle, effect, clinical, study, neurology, treatment, myopathy tirasemtiv, fast-twitch, muscle, efficacy, clinical, study, neuroscience
684	Lack of clpC does not affect sporulation efficiency in Bacillus subtilis cells. Lack,clpC,Bacillus subtilis,sporulation,effect,efficient,retrieval,query Lack,clpC,sporulation,Bacillus subtilis,effect,efficiency Lack,clpC,sporulation,Bacillus subtilis,cells,effect,efficient Lack,clpC,sporulation,Bacillus subtilis,effect,cells Lack,clpC,sporulation,Bacillus subtilis,cells,effect,efficiency
443	GATA-3 is important for hematopoietic stem cell (HSC) function. GATA-3,hematopoietic.stem.cell,function,transcription.factor,molecular.biology,immune.system,stem.cells,research,biological.processes,regulation,gene.expressions,development,biology,science GATA-3,hematopoietic stem cell,function,stem cells,hematopoiesis,molecular biology,transcription factor,immune system GATA-3,hematopoietic.stem.cell,function,stem.cells,immune.system,transcription.factor,molecular.biology,T-cell,differentiation,gene.regulation GATA-3,hematopoietic stem cell,function,molecular biology,immunology,gene expression,stem cells,hematology,DNA binding protein GATA-3,hematopoietic stem cell,function,blood development,molecular biology,gene regulation,stem cell biology
324	Deleting Raptor reduces G-CSF levels. Deleting,Raptor,G-CSF,levels,therapy,treatment,clinical,effect,immunology,pharmacology Deleting,Raptor,G-CSF,levels,therapy,myeloid,dysfunction,biological,agent Deleting,Raptor,G-CSF,levels,therapy,treatment,biological,medicine,hematology,cytokine Deleting,Raptor,G-CSF,levels,bone marrow,dendritic cells,mice,clinical trial,immunology,pharmacology,biotechnology,cytokines,stem cells Deleting,Raptor,G-CSF,levels,bone marrow,neutropenia,immunotherapy
327	Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype. αvβ8 integrin, deletion, spontaneous inflammation, phenotype, mice, knockout, immune response Deletion, αvβ8, inflammatory, phenotype, spontaneous Deletion, αvβ8, spontaneous, inflammatory, phenotype Deletion, αvβ8, spontaneous, inflammatory, phenotype Deletion, αvβ8, spontaneous, inflammatory, phenotype
569	In adult tissue, most T cells are memory T cells. adult tissue, T cells, memory T cells adult tissue, T cells, memory T cells adult tissue, T cells, memory T cells adult tissue, memory T cells, T cells adult tissue, T cells, memory T cells
208	CHEK2 is not associated with breast cancer. CHEK2, breast cancer, genetic, mutation, association, research, oncology, BRCA1, BRCA2 CHEK2,breast cancer,genetic association研究,mutation,BRCA1,BRCA2 CHEK2, breast cancer, genetic testing, mutation, tumor suppressor, BRCA1, BRCA2 CHEK2, breast cancer, genetic, mutation, association, research CHEK2,breast cancer,genetic mutation,association study,RB1 gene,synaptonemal complex protein 3,Cdkn2a gene
690	Less than 10% of the gabonese children with Schimmelpenning-Feuerstein-Mims syndrome (SFM) had a plasma lactate of more than 5mmol/L. Schimmelpenning-Feuerstein-Mims, Gabon, children, plasma, lactate, percentage Schimmelpenning-Feuerstein-Mims, SFM, Gabon, children, plasma, lactate, percentage Schimmelpenning-Feuerstein-Mims, syndrome, Gabon, children, plasma, lactate, level, percentage Schimmelpenning-Feuerstein-Mims, syndrome, Gabon, children, plasma, lactate, level Schimmelpenning-Feuerstein-Mims, SFM, Gabon, children, plasma, lactate, concentration, syndrome
691	Leukemia associated Rho guanine nucleotide-exchange factor represses RhoA in response to SRC activation. Leukemia, RhoGDS, RhoA, SRC, gene expression, signaling pathway Leukemia, RhoGAP, RhoA, SRC, gene expression, oncology, signal transduction Leukemia, RhoGDP-dissociation inhibitor, RhoA, SRC, gene expression, signaling pathway Leukemia, Rho guanine nucleotide-exchange factor, RhoA, SRC activation, gene expression Leukemia, RhoGDI2, RhoA, SRC, signaling, regulation, oncology
692	Leuko-increased blood increases infectious complications in red blood cell transfusion. leukocytes,blood transfusion,infectious complications,red blood cells,increased leukocyte leukocytosis,blood transfusion,infectious complications,red blood cells,white blood cells leukocytosis,blood transfusion,infectious complications,red blood cells Leukocytes,blood transfusion,infectious complications,red blood cells,leuko-reduced Leukocytes,blood transfusion,infectious complications,red blood cells
1316	Transferred UCB T cells acquire a memory-like phenotype in recipients. Transferred, UCB, T cells, memory-like, phenotype, recipients Transferred, UCB, T cells, acquire, memory-like, phenotype, recipients Transferred, UCB, T cells, memory-like, phenotype, recipients Transferred, UCB, T cells, acquire, memory-like, phenotype, recipients T cells, transferred, UCB, memory-like, phenotype, recipients
693	Leuko-reduced blood reduces infectious complications in red blood cell transfusion. Leuko-reduced, blood, infectious, complications, transfusion, red, cells Leuko-reduced, blood, infectious, complications, red, blood, cell, transfusion Leuko-reduced, blood, infectious, complications, red, blood, cell, transfusion leuko-reduced, blood, infectious, complications, red, blood, cell, transfusion Leuko-reduced, blood, transfusion, infectious, complications
452	Gene expression does not vary appreciably across genetically identical cells. gene expression, genetically identical cells, variability, RNA transcription, cellular heterogeneity gene expression, genetically identical cells, variability, bioscience, molecular biology, cell biology gene expression, genetically identical, cells, variability, uniformity gene expression, genetically identical cells, variability, molecular biology, epigenetics, stem cells, identical twins gene expression, genetically identical, cells, variability, biological variation
212	CR is associated with higher methylation age. CR,methylation,age,diet,aging,senescence,geneexpression,longevity,nutrition CR,methylation,age,diet,aging,senescence,longevity,human,epigenetics,mouse,model,study,caloric restriction CR,methylation,age,senescence,longevity,human,study,effect,prediction,model,biomarker CR,methylation,age,senescence,longevity,caloric restriction,gene expression,Aging,biomarker CR,methylation,age,senescence,longevity,dietary,restriction,human,epigenetics,gene,expression,nutrition,aging,biomarker
575	In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon. Saccharomyces_cerevisiae, whole_chromosome_aneuploidy, domesticated_populations, yeast_genetics Saccharomyces_cerevisiae, whole_chromosome_aneuploidy, domesticated_populations, rarity, genetics, yeast_aneuploidy Saccharomyces,cerevisiae,domesticated,populations,whole,chromosome,aneuploidy,uncommon Saccharomyces_cerevisiae, whole_chromosome_aneuploidy, domesticated_populations, uncommon Saccharomyces,cerevisiae,domesticated,populations,whole,chromosome,aneuploidy,frequency,rarity
213	CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery. CRP, postoperative mortality, Coronary Artery Bypass Graft, CABG, predictive CRP,mortality,postoperative,Coronary,Artery,Bypass,Graft,CABG,surgery,predictive CRP, postoperative mortality, Coronary Artery Bypass Graft, CABG, predictive, surgery CRP, postoperative mortality, Coronary Artery Bypass Graft, CABG, predictive, surgery CRP,mortality,postoperative,CABG,surgery,prediction,coronary,artery,bypass,graft
577	In mice, P. chabaudi parasites are able to proliferate faster early in infection when inoculated at lower numbers than when inoculated at high numbers. mice,P.chabaudi,parasites,proliferation,infection,inoculation,numbers mice,P.chabaudi,infection,proliferation,inoculation,dosage,virus,biology P.chabaudi, parasites, proliferation, mice, infection, inoculation, number, differential mice,P.chabaudi,parasites,proliferation,infection,inoculation,dose,response mice,P.chabaudi,parasites,proliferation,infection,inoculation,dosage,virulence
578	In mouse models, the loss of CSF1R facilitates MOZ-TIF2-induced leuekmogenesis. mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leukemia, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis
216	CX3CR1 on the Th2 cells impairs T cell survival CX3CR1,Th2,cells,T cell,survival,immunology,molecular biology,immune response,inflammation CX3CR1,Th2,cells,T细胞存活,immunity,inflammation,immune response CX3CR1,Th2,cells,T细胞存活,immune response,inflammation,molecular biology,immunology CX3CR1,Th2,cells,T cell,survival,immunity,inflammation,biology,immunology,molecular biology CX3CR1, Th2, T cells, survival, immune response
217	CX3CR1 on the Th2 cells promotes T cell survival CX3CR1, Th2 cells, T cell survival, immune response, cytokines, signaling molecules, immunology, inflammation, adaptive immunity CX3CR1,Th2,cells,T细胞生存,CX3CR1受体,Th2免疫细胞,T淋巴细胞存活 CX3CR1, Th2 cells, T cell survival, immunology, cytokines, signaling, inflammation, immune response CX3CR1,Th2,cells,T cell,survival,biology,immunology,molecular生物学,免疫学,分子免疫学 CX3CR1,Th2,cells,T cell,survival,immunology,molecular biology,immune response
338	Dexamethasone decreases risk of postoperative bleeding. Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthesia, inflammation, hemorrhage, corticosteroid Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthesia, inflammatory response, hemostasis Dexamethasone, postoperative bleeding, risk reduction, surgery, medicationeffect, anesthesiainteraction Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthetic effects, inflammation, hemorrhage Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthesia, inflammation, blood loss
218	CX3CR1 on the Th2 cells promotes airway inflammation. CX3CR1,Th2,cells,airway,inflammation,microglia,cytokines,immune,response,BMI,asthma CX3CR1,Th2,cells,airway,inflammation,molecular,biology,immunology,cytokines,asthma,innate,immune,system,T-helper,cells,MCP-1,CCL2 CX3CR1, Th2 cells, airway inflammation, immune response, asthma, cytokines, chemokines, immune cells, lung, allergy CX3CR1,Th2,cells,airway,inflammation,molecular,biomarker,immunology,asthma,immuneresponse CX3CR1, Th2 cells, airway inflammation, immune response, cytokines, asthma, allergy
219	CX3CR1 on the Th2 cells suppresses airway inflammation. CX3CR1,Th2,cells,inflammation,airway,suppresses CX3CR1,Th2,cells,airway,inflammation,suppresses CX3CR1, Th2 cells, airway inflammation, immunology, cytokines, allergy, asthma, immune response CX3CR1, Th2 cells, airway inflammation, immunology, cytokines, asthma, immune suppression CX3CR1,Th2,cells,inflammation,airway,suppresses
1319	Transplanted human glial cells can differentiate within the host animal. transplant, glial, cells, differentiation, host, animal, human transplanted, human, glial, cells, differentiate, host, animal transplant, human, glial, cells, differentiation, host, animal transplanted, human, glial, cells, differentiate, host, animal transplantation, glial, cells, differentiation, host, animal, human
100	All hematopoietic stem cells segregate their chromosomes randomly. hematopoietic,stem,cells,chromosomes,randomly,segregate,mitosis,genetics,biology,cytogenetics,hematopoiesis hematopoietic,stem,cells,chromosome,segregation,randomly,mitosis,binary,fission hematopoietic,stem,cells,chromosome,segregation,random,mitosis,biology,genetics hematopoietic,stem,cells,chromosome,segregation,random,mitosis,genetics,biology,cytology,molecular biology hematopoietic,stem,cells,chromosomes,randomly,segregate,DNA,mitosis,human,biology,research,genetics,science,division,dividing,cell,cycle,process,ploidy,equality
1204	The combination of H3K4me3 and H3K79me2 is found in quiescent hair follicle stem cells. H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,DNA,lysine,methylation,regulation H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,DNA,lysine,modification,methylation,chromatin,marker,proteins,regulation,geneexpression,biochemistry,molecularbiology,genetics,Epigenetics,Cancer,Biotechnology,RegenerativeMedicine,CellCycle,Skinbiology H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,DNA,chromatin,mark,regulation,transcription,biochemistry,methylation,pattern,tissue,development,Epigenetics,marker,molecular,bioscience,genetics,proteins,marker,expression,cellular,biology,analysis,research,science,genome,omics,genomic,markers,identification,biomarker,cell,lineage,marker,signaling,interactions,proteomics,metabolomics,transcriptomics,fluores H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,chromatin,markers,epigenetics H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,chromatin,markers,transcription,regulation
343	Diabetic patients with acute coronary syndrome experience increased short-term and long-term risk for bleeding events. diabetes, acute coronary syndrome, bleeding, diabetic patients, short-term risk, long-term risk diabetes, acute coronary syndrome, bleeding, diabetic patients, short-term risk, long-term risk diabetes, acute coronary syndrome, bleeding, diabetic patients, short-term risk, long-term risk Diabetes, Acute Coronary Syndrome, Bleeding, Risk, Diabetic Patients, Short-Term, Long-Term diabetes, acute coronary syndrome, bleeding, risk, diabetic patients, short-term, long-term
1202	The center of the granuloma in an immune cell induces a pro-inflammatory immune response. granuloma, immune cell, pro-inflammatory, center, immune response granuloma, immune cell, pro-inflammatory, response granuloma, immune cell, pro-inflammatory, response granuloma, immune cell, center, pro-inflammatory, response granuloma, immune cell, pro-inflammatory, center, immune response
587	In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, less than ten percent of the cells with green florescent colocalize with cell proliferation markers. transgenic,mice,green,florescent,protein,Sox2,promoter,cell,proliferation,markers,colocalize transgenic,mice,green,florescent,protein,Sox2,promoter,colocalize,cell,proliferation,markers transgenic,mice,green,florescent,protein,Sox2,promoter,colocalize,cell,proliferation,markers transgenic,mice,green,florescent,protein,Sox2,promoter,cells,colocalize,proliferation,markers transgenic,mice,green,florescent,protein,Sox2,promoter,cell,proliferation,markers,colocalize
1200	The binding orientation of the ML-SA1 activator at hTRPML2 is different from the binding orientation of the ML-SA1 activator at hTRPML1. binding orientation, ML-SA1, activator, hTRPML2, hTRPML1 binding orientation, ML-SA1 activator, hTRPML2, hTRPML1 binding orientation, ML-SA1 activator, hTRPML2, hTRPML1 binding orientation, ML-SA1, activator, hTRPML2, hTRPML1, protein, channel, regulation, structure, pharmacology binding orientation, ML-SA1 activator, hTRPML2, hTRPML1
589	In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events. ADHD, medications, cardiovascular, risk, adults, serious, events, current, remote ADHD, medications, cardiovascular, events, risk, adults, young, middle-aged, current, remote ADHD, medications, cardiovascular, events, adults, risk, serious ADHD, medications, cardiovascular, events, adults, risk, serious, current, remote, use ADHD, medications, young, middle-aged, adults, cardiovascular, events, risk, current, remote, use
1320	Transplanted human glial progenitor cells are incapable of forming a neural network with host animals' neurons. transplanted, human, glial, progenitor, cells, neural, network, host, animals, neurons transplanted, human, glial, progenitor, cells, neural, network, host, animals, neurons transplant, human, glial, progenitor, cells, incapable, form, neural, network, host, animals, neurons transplant, human, glial, progenitor, cells, incapable, form, neural, network, host, animals, neurons transplant, human, glial, progenitor, cells, neural, network, host, animals, neurons
903	PD-1 triggering on monocytes reduces IL-10 production by monocytes. PD-1, monocytes, IL-10, immunology, cytokines, immune response PD-1, monocytes, IL-10, immune response, cytokines, immunotherapy PD-1, monocytes, IL-10, production, immune, response, cytokine PD-1, monocytes, IL-10, immune response, cytokines, immunotherapy PD-1, monocytes, IL-10, production, immunology, immune response, cytokines
904	PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells. PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells PDPN,motility,stromal surfaces,C-type lectin receptor,dendritic cells,actin cytoskeleton PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells PDPN,motility,stromal surfaces,C-type lectin receptor,dendritic cells,actin cytoskeleton
1207	The composition of myosin-II isoform switches from the polarizable B isoform to the more homogenous A isoform during hematopoietic differentiation. myosin-II, isoform, B, A, hematopoietic, differentiation, polarization, homogeneity myosin-II, isoform, hematopoietic, differentiation, B, A, polarity, homogeneity myosin-II, isoform, B, A, hematopoietic, differentiation, polarization, homogeneity myosin-II, isoform, polarizable, B, homogenous, A, hematopoietic, differentiation myosin-II, isoform, B, A, hematopoietic, differentiation, polarization, homogeneity