907	PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes. PGE2,intestinal,tumor,growth,expression,tumor suppressing,DNA repairgenes PGE2,intestinal,tumor,growth,expression,tumor suppressing,DNA repairgenes PGE2,intestinal,tumor,growth,tumor suppressing,gene expression, DNA repair PGE2,intestinal,tumor,growth,expression,tumor suppressing,DNA repair genes PGE2,intestinal,tumor,growth,tumor suppressing,DNA repair,gene expression
350	Discrimination between the initiator and elongation tRNAs depends on the translation initiation factor IF3. discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3 discrimination, initiator, elongation, tRNAs, translation, initiation, factor, IF3
230	Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink less that non-carries. alcohol, aldehyde, dehydrogenase, deficiency, carriers, mutation, consumption, non-carriers alcohol, aldehyde, dehydrogenase, deficiency, carriers, mutation, drinking, habits, genetics alcohol, aldehyde, dehydrogenase, deficiency, carriers, non-carriers, drinkingbehavior alcohol, aldehyde, dehydrogenase, deficiency, carriers, mutation, drinking, habits, genetics, liver, metabolism alcohol, aldehyde, dehydrogenase, deficiency, carriers, mutation, drinking, habits, genetics, metabolism
593	Incidence of heart failure decreased by 10% in women since 1979. heart failure, incidence, women, 1979, decreased heart failure, incidence, women, 1979, decreased heart failure, incidence, women, 1979, decrease heart failure, incidence, women, 1979, decreased heartfailure, incidence, women, 1979, decreased
1216	The extracellular domain of TMEM27 is cleaved in human beta cells. extracellular, domain, TMEM27, cleaved, human, beta, cells extracellular domain,TMEM27,cleavage,human,beta cells,protein processing extracellular, domain, TMEM27, cleavage, human, beta, cells extracellular domain,TMEM27,human,beta cells,cleavage extracellular, domain, TMEM27, cleavage, human, beta, cells
1337	Ubiquitin ligase UBC13 generates a K63-linked polyubiquitin moiety at PCNA K164. Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164 Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164 Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164 Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164 Ubiquitin, ligase, UBC13, K63, polyubiquitin, PCNA, K164
232	Cataract and trachoma are the primary cause of blindness in Southern Sudan. Cataract,trachoma,blindness,Southern,Sudan,causes Cataract,trachoma,blindness,Southern,Sudan,epidemiology,health,malnutrition,diagnosis,treatment Cataract,trachoma,blindness,Southern,Sudan,Eyediseases Cataract,trachoma,blindness,Southern,Sudan,causes Cataract,trachoma,blindness,Southern,Sudan,epidemiology,malaria,diagnosis,treatment
1336	UCB T cells reduce TCR diversity after transplantation. UCB, T cells, TCR, transplantation, immune system, stem cells, bone marrow, T cell receptor, diversity reduction, hematopoietic stem cells UCB, T cells, TCR diversity, transplantation UCB, T cells, TCR diversity, transplantation UCB, T cells, TCR diversity, transplantation UCB, T cells, TCR diversity, transplantation, immune system, stem cells, transplantation immunology, T cell receptor
233	Cell autonomous sex determination in somatic cells does not occur in Galliformes. sex determination, somatic cells, Galliformes, cell autonomy, aves, biology, genetics Cell,autonomous,sex,determination,somatic,cells,Galliformes,avian,birds,chromosomes,genetics,molecular,biology,development,mechanism cell,autonomous,sex,determination,somatic,cells,Galliformes,avian,biology,molecular,genetics Cell, autonomous, sex, determination, somatic, cells, Galliformes, birds, genetics, mechanism cell,autonomous,sex,determination,somatic,cells,Galliformes,birds,genetics,molecular,biology,reproduction
354	Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis. downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,molecular,biology,cancer,pathway,mechanism,protection,gene,expression,cellular,functionality,tumor.suppression,protein,localization,cellular.pathology downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,molecular,cancer,biology,genetics,membrane,protein,expression,pattern,cellular,morphology downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,molecular,mechanism,gene,expression,tumor.suppression Downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,molecular,cancerbiology,proteins,tumor.suppression,gene.regulation,cell.adhesion,morphogenesis downregulation,mislocalization,Scribble,cell,transformation,mammary,tumorigenesis,cancer,protein,localization,cellular,dysfunction,tumor,scrib gene
475	Glycolysis is one of the primary glycometabolic pathways in cells. glycolysis, primary, glycometabolic, pathways, cells Glycolysis, glycometabolic, pathways, cells Glycolysis, glycometabolic, pathways, cells glycolysis, glycometabolic, pathways, cells glycolysis, glycometabolic, pathways, cells
113	Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency. Angiotensin converting enzyme inhibitors, functional renal insufficiency, risk, medication, kidney, nephrology, hypertension, side effects Angiotensin, converting, enzyme, inhibitors, renal, insufficiency, risk, association Angiotensin converting enzyme inhibitors, functional renal insufficiency, risk, kidney failure Angiotensin, converting, enzyme, inhibitors, functional, renal, insufficiency, risk Angiotensin, converting, enzyme, inhibitors, increased, risk, functional, renal, insufficiency
1335	UCB T cells maintain high TCR diversity after transplantation. UCB, T cells, TCR diversity, transplantation, immune system, stem cells, bone marrow transplantation, T cell receptor UCB, T cells, TCR diversity, transplantation UCB, T cells, TCR diversity, transplantation, immune system UCB, T cells, TCR diversity, transplantation, immune system, stem cells, transplantation immunity, T cell receptor UCB, T cells, TCR diversity, transplantation, immune system
597	Incidence rates of cervical cancer have decreased. cervical cancer, incidence rates, decreased, epidemiology cervical cancer, incidence rates, decreased, trends, epidemiology cervical_cancer, incidence_rates, decrease, cancer_rates, health_data, oncology, gynecology, medical_statistics cervical cancer, incidence, rates, decrease, trends cervical cancer, incidence rates, decrease, trends, prevalence
1213	The deregulated and prolonged activation of monocytes has deleterious effects in inflammatory diseases. monocytes, deregulation, activation, inflammatory, diseases, deleterious, effects deregulation, monocytes, prolonged, activation, inflammatory, diseases, deleterious, effects monocytes,deregulation,activation,inflammation,deleterious,effects,diseases monocytes, deregulation, activation, inflammatory, diseases, deleterious, effects monocytes,deregulation,activation,inflammatory,diseases,deleterious,effects
598	Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer. cervical_cancer, incidence_rates, screening_programs, cytology, uterine_cervical_cancer cervical_cancer, incidence_rates, screening_programs, cytology, uterine_cervical_cancer cervical_cancer, incidence_rates, screening_programs, cytology, uterine_cervical_cancer incidence,rates,cervical,cancer,screening,programs,cytology,uterine,detect cervical_cancer, incidence_rates, screening_programs, cytology, uterine_cervical_cancer
115	Anthrax spores can be disposed of easily after they are dispersed. anthrax, spores, disposal, dispersion, biosecurity anthrax, spores, disposal, dispersion, biosecurity anthrax, spores, disposal, dispersion, biosecurity anthrax, spores, disposal, dispersal, easy anthrax, spores, disposal, dispersed
236	Cell autonomous sex determination in somatic cells occurs in Passeriformes. cell,autonomous,sex,determination,somatic,cells,Passeriformes,birds,molecular,biology,genetics,endocrinology,female,male,heterogametic,homogametic Cell,autonomous,sex,determination,somatic,cells,Passeriformes,genetics,molecular,biology Cell,autonomous,sex,determination,somatic,cells,Passeriformes,birds,molecular,biology,genetics,chromosomes,hormones,development,phenomenon,species,traits Cell, autonomous, sex, determination, somatic, cells, Passeriformes, birds, genetics, biology, chromosome, sexing, mechanism Cell, autonomous, sex, determination, somatic, cells, Passeriformes, birds, genetics, biology, chromosome, regulation
478	Golli-deficient T-cells prefer to differentiate into an anergic phenotype in the adaptive immune response when there are increased levels of Ca2+ in the cytosol. Golli-deficient,T-cells,anergic,phenotype,adaptive,immune,response,Ca2+,cytosol Golli-deficient, T-cells, anergic, phenotype, adaptive, immune, response, Ca2+, cytosol Golli, T-cells, anergy, adaptive immune response, Ca2+, cytosol Golli-deficient,T-cells,anergy,adaptive immune response,Ca2+,cytosol Golli, T-cells, anergy, adaptive immune response, Ca2+, cytosol
1332	Tumor necrosis factor alpha (TNF-α) and interleukin-1 (IL-1) are pro-inflammatory cytokines that inhibit IL-6 and IL-10. Tumor,necrosis,factor,alpha,IL-1,pro-inflammatory,cytokines,IL-6,IL-10,inhibit Tumor,necrosis,factor,alpha,TNF-α,interleukin,IL-1,pro-inflammatory,cytokines,IL-6,IL-10,inhibit Tumor,necrosis,factor,alpha,IL-1,pro-inflammatory,cytokines,IL-6,IL-10,inhibit Tumor,necrosis,factor,alpha,TNF-α,interleukin,1,IL-1,pro-inflammatory,cytokines,IL-6,IL-10,inhibit Tumor,necrosis,factor,alpha,TNF-α,interleukin,1,pro-inflammatory,cytokines,IL-6,IL-10,inhibit
237	Cells lacking clpC have a defect in sporulation efficiency in Bacillus subtilis. cells,clpC,Bacillus subtilis,sporulation,defect,molecular biology,proteolysis cells,clpC,Bacillus subtilis,sporulation,defect Bacillus_subtilis, sporulation, clpC, cell_defect Cells,clpC,Bacillus subtilis,sporulation,defect Cells,clpC,Bacillus subtilis,sporulation,defect
238	Cells undergoing methionine restriction may activate miRNAs. cells,methionine restriction,miRNAs,activation,microRNAs Cells,methionine,restriction,miRNAs,activation,gene regulation,microRNAs,methionine starvation,proteomics,transcriptional profiling cells,methionine restriction,miRNAs,activation,synthesis,metabolism Cells,methionine restriction,miRNAs,activation,gene expression,microRNAs cells,methionine,restriction,miRNAs,activation,microRNAs,gene regulation,mRNA,synthesis,biochemistry,metabolism,biological response,nutrition,starvation,therapy,treatment
118	Antibiotic induced alterations in the gut microbiome reduce resistance against Clostridium difficile Antibiotics,gut,microbiome,Clostridium difficile,resistance,alterations,intestinal flora Antibiotics,gut,microbiome,Clostridium difficile,resistance,alterations,induced Antibiotics,gut,microbiome,Clostridium difficile,resistance,alterations,therapy,population,health,effectiveness Antibiotics,gut,microbiome,Clostridium,difficile,resistance,alterations Antibiotics,gut,microbiome,Clostridium,difficile,resistance,alterations,therapy,bacterial,effects,probiotics,fermentation,dysbiosis
239	Cellular aging closely links to an older appearance. cellular,aging,skin,ageing,appearance,damage,molecular,biological,aging_process,senescence cellular,aging,skin,ageing,biology,deterioration,photoaging,chronological,aging,evity cellular, aging, appearance, skin, wrinkles, aging process, telomeres, senescence cellular aging, skin aging, biological age, wrinkles, senescence, telomere, DNA damage, oxidative stress, mitochondrial function cellular,aging,appearance,老化,皱纹,弹性,色素沉着
911	PKG-la plays an essential role in expression of pain hypersensitivity in PGK-la knockout mice. PKG-la,pain,hypersensitivity,PGK-la knockout mice,expression PKG-la,pain,hypersensitivity,PGK-la knockout mice,expression PKG-la,pain,hypersensitivity,PGK-la knockout mice,mouse model,genetic knockout PKG-la,pain,hypersensitivity,PGK-la knockout mice,mice,retrieval Keywords,Query,Expression PKG-la,pain,hypersensitivity,PGK-la knockout mice,expression,mice,model
913	PPAR-RXRs are inhibited by PPAR ligands. PPAR,RXRs,inhibition,ligands,dimers,regulation,gene(expression) PPAR,RXRs,inhibition,ligands,transcription,factors,dimers,regulation PPAR,RXRs,inhibition,ligands,dimerization,gene regulation,lipid metabolism PPAR, RXR, inhibitors, PPAR ligands, transcription factors PPAR, RXR, inhibitors, PPAR-ligands
914	PPAR-RXRs can be activated by PPAR ligands. PPAR,RXRs,ligands,activation,molecular,target,disease,treatment,transcription,factors,thyroid,hormone,receptors,drug,therapy PPAR,RXRs,ligands,activation,gene,dimerization,molecules,transcription,factors PPAR,RXRs,ligands,activation,gene,dimers,transcription,fatty acids PPAR,RXRs,ligands,activation,gene,dimers,transcription,fatty acids PPAR,RXRs,ligands,activation,gene,dimers,molecules,binding,transcription,factors
1339	Ultrasound guidance significantly raises the number of traumatic procedures when attempting needle insertion. ultrasound, guidance, needle, insertion, traumatic, procedures, significantly, raises, number ultrasound, guidance, traumatic, needle, insertion, procedures, significantly, number ultrasound, guidance, needle, insertion, traumatic, procedures, significantly, raises ultrasound, guidance, traumatic, needle, insertion, procedures, significantly, raises ultrasound, guidance, traumatic, needle, insertion, procedures, significantly, number
13	5% of perinatal mortality is due to low birth weight. perinatal,mortality,low,birth,weight,pregnancy,infant perinatal,mortality,low,birth,weight,pregnancy,infant perinatal,mortality,low,birth,weight,pregnancy,infant perinatal,mortality,low,birth,weight,pregnancy,infant perinatal,mortality,low,birth,weight,pregnancy,infant,health,factors,risk
1110	Suboptimal nutrition is not predictive of chronic disease suboptimal,nutrition,chronic,disease,prediction,health,outcome,factors,risk,diets,wellness,food,population,studies,research,prevention,obesity,mortality,quality,assessment suboptimal,nutrition,chronic,disease,predictive,factors,health,outcomes,diets,vitamins,minerals suboptimal,nutrition,chronic,disease,predictive,health,outcomes,diets,malnutrition,vitamins,minerals,obesity,cardiovascular,diabetes,mortality suboptimal,nutrition,chronic,disease,predictive,factors,health,diets,risks,prevention nutrition, suboptimal, chronic, disease, predictive, diet, health, malnutrition, epidemiology
1352	Upregulation of mosGCTL-1 is induced upon infection with West Nile virus. upregulation,mosGCTL-1,West,Nile,virus,infection,immunology,molecularbiology,viralresponse upregulation, mosGCTL-1, West Nile virus, infection upregulation,mosGCTL-1,West,Nile,virus,infection,immune,response upregulation,mosGCTL-1,West Nile virus,infection,immune response,viral infection,molecular biology,gene expression,virus-host interaction upregulation,mosGCTL-1,West,Nile,virus,infection,immune/response,expression,molecular/pathway
362	During the primary early antibody response activated B cells migrate toward the inner-and outer paracortical areas where oxysterol accumulation is generated by stromal cells. antibody response, activated B cells, migration, paracortical areas, oxysterol accumulation, stromal cells antibody response, activated B cells, migration, paracortical areas, oxysterol, stromal cells activated B cells,migrate,paracortical areas,oxysterol,stromal cells,primary early antibody response primary, antibody, response, activated, B, cells, migrate, paracortical, areas, oxysterol, stromal, cells primary, early, antibody, response, activated, B, cells, migrate, paracortical, areas, oxysterol, accumulation, stromal, cells
1107	Subcutaneous fat depots undergo extensive browning processes after cold exposure. subcutaneous,fat,depots,browning,cold,exposure,processes subcutaneous,fat,depots,browning,cold,exposure,processes,adipose,tissue,thermogenesis,white,brown,beige,lipids,metabolism,energy,homeostasis,activation,molecular,mechanisms,angiogenesis,innervation,nuclear,potentiation,thermoregulation subcutaneous,fat,depots,browning,cold,exposure,molecular,mechanisms,thermogenic,adipocytes,WAT,BAT,energy,metabolism,adipose,tissue,activation,norepinephrine,mitochondria,UCP1,temperature,regulation,transcription,factors,enzymes,oxidative,phagocytosis,inflammation,innervation,angiogenesis subcutaneous,fat,depots,browning,cold,exposure,processes subcutaneous fat, browning, cold exposure, adipose tissue, thermogenesis, white fat, brown fat, metabolism, lipid, inflammation
1	0-dimensional biomaterials show inductive properties. 0-dimensional,biomaterials,inductive,properties,nanomaterials,molecular,scaffolds,tissueengineering,growth,factors,effectiveness,biocompatibility biomaterials, dimensionality, induction, tissue engineering, nanomaterials, bioactive materials, scaffolds 0-dimensional, biomaterials, inductive, properties 0-dimensional,biomaterials,inductive,properties,nanomaterials,catalysts,semiconductors,MOFs,TiO2 0-dimensional,biomaterials,inductive,properties,nanomaterials,molecular,self-assembling,biocompatibility
1226	The loss of the TET protein functions may have dire biological consequences, such as myeloid cancers. TET protein, myeloid cancers, biological consequences TET protein,function,dire biological consequences,myeloid cancers TET protein,functional loss,biological consequences,myeloid cancers TET protein,function,dire biological consequences,myeloid cancers TET protein,function,myeloid cancers,biological consequences,molecular biology,cancer biology,methylation,dire outcomes
1104	Stroke patients with prior use of direct oral anticoagulants have a lower risk of in-hospital mortality than stroke patients with prior use of warfarin. stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality,risk stroke,prior use,direct oral anticoagulants,warfarin,in-hospital mortality
1225	The locus rs647161 is associated with colorectal carcinoma. locus, rs647161, colorectal, carcinoma, genetic, association, variant locus, rs647161, colorectal, carcinoma, genetic, association, variant, cancer locus, rs647161, colorectal, carcinoma, genetic, association, variant locus, rs647161, colorectal, carcinoma, genetic, association, variant rs647161,colorectal,carcinoma,genetic,polymorphism,association,study,single,nucleotide,population,gene,mutation,variant,frequency,risk,Allele,DNA,variant,genomics,biomarker,heritability,predisposition,test,SNP,disease,marker,genome,mutation,biological,clinical,research,analysis,genotype,expression,phenotype,epidemiology, oncology,medicine,biology,genetics,health,translational,public,genetic variation,genetic testing,genetic counseling,
124	Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata. Antiretroviral, therapy, tuberculosis, CD4, strata, HIV, treatment, infection, prevalence, reduction Antiretroviral, therapy, tuberculosis, CD4, strata, HIV, treatment, prevention Antiretroviral, therapy, tuberculosis, CD4, strata, reduction, HIV, infection antiretroviral, therapy, tuberculosis, CD4, strata, reduction, HIV Antiretroviral, therapy, tuberculosis, CD4, strata, HIV, infection, treatment, prevention, epidemiology
3	1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants. 1000Genomes, genetic variation, rare variants, penetrance, common variants, genome mapping 1000 Genomes Project,rare variants,penetrance,genetic sequence variation,common variants,mapping genomics 1000 Genomes Project,rare variants,genetic sequence variation,penetrance,common variants,mapping genomics 1000Genomes, genetic, sequence, variation, rare, variants, penetrance, common, effects 1000Genomes, genetic, sequence, variation, rare, variants, penetrance, common, effects
1344	"Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging. p53, up-regulation, cancer resistance, molecular events, shortened lifespan, senescent cells, accelerated aging up-regulation,p53, pathway,molecular events,cancer resistance,senescence,accelerated aging,lifespan,senescent cells up-regulation,p53,pathway,molecular	events,cancer	resistance,senescence,shortened	lifespan,accelerated	aging up-regulation,p53, pathway,molecular events,cancer resistance,senescent cells,accelerated aging,shortened lifespan p53, up-regulation, cancer, resistance, lifespan, senescent, cells, aging, molecular, events"
5	1/2000 in UK have abnormal PrP positivity. 1/2000,,UK,,abnormal,,PrP,,positivity 1/2000, UK, abnormal, PrP, positivity, prevalence, disease, genetics, neuroscience 1/2000, UK, abnormal, PrP, positivity, prion, disease, prevalence 1/2000, UK, abnormal, PrP, positivity, prion, disease, prevalence 1/2000, UK, abnormal, PrP, positivity, neurodegenerative, disease, variant, CJD, vCJD
127	Arginine 90 in p150n is important for interaction with EB1. arginine, p150grip, EB1, interaction, protein, domain, residue arginine, p150grip, EB1, proteininteraction, binding site Arginine, p150gelsolin, EB1, interaction, protein, aminoacid, residue arginine, p150grip, EB1, interaction, protein, residue, binding arginine, p150grip, EB1, protein interaction, residue, structural role
248	Chenodeosycholic acid treatment increases whole-body energy expenditure. Chenodeoxycholic,acid,treatment,energy,expenditure,body,metabolism,liver,hepatic,bile,hormones,obesity,weight,loss,therapeutics,mechanism,clinical,effectiveness Chenodeoxycholic, acid, treatment, energy, expenditure, metabolism, obesity, liver, bile, salts Chenodeoxycholic,acid,treatment,energy,expenditure,body,fat,burning,liver,metabolism,hormones,bile,acidotherapy Chenodeoxycholic,acid,treatment,energy,expenditure,body,metabolism,human,experiment,clinical,study Chenodeoxycholic,acid,treatment,energy,expenditure,body,metabolism,bile,hormone,liver,geneexpression,therapeutics,obesity,fat,burn,weightloss,diet,activity
1100	Statins increase blood cholesterol. statins, cholesterol, blood, level, lipid, treatment, medication, cardiovascular, reduction statins, cholesterol, blood, levels, lipid, treatment, medication statins, cholesterol, medication, blood, level, treatment, lipid, reduction, heart, disease statins, cholesterol, medication, lipid, treatment, lowering, heart, disease statins, cholesterol, blood, medication, lipid, level, treatment, cardiovascular, reduction
1221	The genomic aberrations found in matasteses are very similar to those found in the primary tumor. genomic, aberrations, metastases, primary, tumor, similarity genomic, aberrations, metastases, primary, tumor, similar genomic, aberrations, metastases, primary, tumor, similar genomic, aberrations, metastases, primary, tumor, similar genomic, aberrations, metastases, primary, tumor, similarity
128	Arterioles have a larger lumen diameter than venules. arterioles, lumen, diameter, venules arterioles,venules,lumen,diameter,anatomy,vasculature,biology,circulatory系统 arterioles, lumen, diameter, venules arterioles, lumen, diameter, venules arterioles, lumen, diameter, venules
249	Chenodeosycholic acid treatment reduces whole-body energy expenditure. Chenodeoxycholic,acid,treatment,energy,expenditure,reduces,body,weight管理,控制 Chenodeoxycholic,acid,treatment,energy,expenditure,reduces,body,metabolism,liver,hepatic,obesity,human,clinical,effect,mechanism Chenodeoxycholic,acid,treatment,energy,expenditure,body,weight,metabolism,liver,bile,acid,gallstones,obesity,diet,therapy,hormones,lipids,hepatology,metabolomics,nutrition,pharmacology,clinical,study,mechanism,therapeutics Chenodeoxycholic,acid,treatment,energy,expenditure,body,weight,metabolism,human,study,liver,hepatic Chenodeoxycholic,acid,treatment,energy,expenditure,body,fat,metabolism,obesity,liver,hepatic
129	Articles published in open access format are less likely to be cited than traditional journals. openaccess,citation,trend,traditionaljournals,retrieval,publication格式 openaccess,citation,trend,journal,publishing,model,impact因子,research,availability,readership,peer-reviewed open access,journal articles,citation frequency,traditional journals,research dissemination,publishing formats,citation impact openaccess,citations,traditionaljournals,publishing,model,journalimpact,academic,research,availability,visibility,electronicpublishing openaccess,citations,traditionaljournals,publishingFormats,researchImpact
800	Modifying the epigenome in the brain affects the normal human aging process by affecting certain genes related to neurogenesis. epigenome, brain, aging, neurogenesis, genes epigenome, brain, aging, neurogenesis, genes epigenome, brain, aging, neurogenesis, gene modification epigenome, brain, aging, neurogenesis, genes epigenome, brain, aging, neurogenesis, genes
921	Participating in six months of physical activity improves cognitive functioning. physical activity,cognitive functioning,six months,improvement,participation,brain function,motor skills,mental health physical activity,cognitive functioning,six months,participation,retrievalKeywords physical activity,cognitive functioning,six months,improvement,participation,exercise,intervention研究 physicalactivity,cognitivefunctioning,months,retrieval,improvement,participation physicalactivity,cognitivefunctioning,months,retrieval,improvement,participation
922	Patients in stable partnerships have a faster progression from HIV to AIDS. HIV, AIDS, partnership, stable, progression, patients HIV, AIDS, partnership, stable, progression, patients HIV, AIDS, partnership, stable, progression, patients HIV, AIDS, partnership, stable, progression, patients HIV, AIDS, partnership, stable, progression, patients
805	Monoclonal antibody targeting of N-cadherin inhibits metastasis. monoclonal antibody,N-cadherin,metastasis,inhibition,cancertherapy,moleculartargeting,biochemistry Monoclonal抗体,N-cadherin,metastasis,inhibition,cancertherapy,molecularbiology,immunotherapy Monoclonal antibody,N-cadherin,metastasis,inhibition,cancer,treatment,biotechnology,moleculartherapy,prognosis Monoclonal抗体,N-cadherin,metastasis,inhibition,cancertherapy,molecularbiology,biochemistry,immunotherapy,tumorbiology Monoclonal抗体,N-cadherin,metastasis,inhibition,cancertherapy,molecularbiology,biochemistry,tumorimmuneresponse
808	Most termination events in Okazaki fragments are sequence specific. Okazaki fragments, termination events, sequence specificity, DNA replication Okazaki fragments, termination events, sequence specificity, DNA replication Okazaki fragments, termination events, sequence specificity Okazaki fragments, termination events, sequence specificity, DNA replication Okazaki fragments, termination events, sequence specificity
1121	Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites. synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites Synaptic activity, brain derived neurotrophic factor, postsynaptic dendrites, local release synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites synaptic activity, local release, brain derived neurotrophic factor, postsynaptic dendrites Synaptic activity, brain derived neurotrophic factor, postsynaptic dendrites, neurotransmission, neurotrophins, neuronal plasticity, signaling pathways
1363	Venules have a thinner or absent smooth layer compared to arterioles. venules, arterioles, smooth muscle, endothelium, blood vessels, thickness, lumen venules, arterioles, smooth muscle, thin壁, blood vessels venules, arterioles, smooth muscle, blood vessels, endothelium, diameter, anatomy venules, arterioles, smooth muscle, thickness, blood vessels venules, arterioles, smooth muscle, endothelium, blood vessels, diameter, capillaries
1241	The myocardial lineage develops from cardiac progenitors of mesodermal origin. myocardial lineage, cardiac progenitors, mesodermal origin myocardial, lineage, cardiac, progenitors, mesodermal myocardial, lineage, cardiac, progenitors, mesodermal, development myocardial, lineage, cardiac, progenitors, mesodermal, development myocardial lineage, cardiac progenitors, mesodermal origin
1362	Venules have a larger lumen diameter than arterioles. venules, arterioles, lumen, diameter, blood vessels venules, arterioles, lumen, diameter, blood vessels venules, arterioles, lumen, diameter, blood vessels venules, arterioles, lumen, diameter, blood vessels venules, lumen, diameter, arterioles
491	HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years HNF4A,mutations,diabetes,carrier,age,14years HNF4A,mutations,diabetes,mutant,carriers,age,14_years HNF4A,mutations,diabetes,carrier,age,14years HNF4A,mutations,diabetes,carriers,age,14_years HNF4A,mutations,diabetes,carriers,age,14years
130	Articles published in open access format are more likely to be cited than traditional journals. openaccess,citation,tendency,traditionaljournals,publishing格式 openaccess,citation,trend,traditionaljournals,research,publishing,model,impact因子,accessibility openaccess,citations,journals,research,publication,model openaccess,citation,trend,traditionaljournals,retrieval,articles,publishing格式: 关键词1,关键词2,关键词3,... openaccess,citations,traditionaljournals,researcharticles,publicationformat,popularity,academicpublishing
132	Aspirin inhibits the production of PGE2. aspirin,PGE2,inhibition,prostaglandin,E2,anti-inflammatory aspirin,PGE2,inhibition,prostaglandin,E2,nonsteroidalanti-inflammatorydrug,N-SAID aspirin, inhibits, PGE2, prostaglandin, production aspirin,PGE2,inhibition,prostaglandin,E2,anti-inflammatory aspirin, PGE2, inhibition, prostaglandin, production
133	Assembly of invadopodia is triggered by focal generation of phosphatidylinositol-3,4-biphosphate and the activation of the nonreceptor tyrosine kinase Src. invadopodia, phosphatidylinositol-3,4-biphosphate, Src, assembly, focal, activation, nonreceptor tyrosine kinase invadopodia, phosphatidylinositol-3,4-biphosphate, Src, tyrosine kinase, assembly, focal generation Assembly, invadopodia, phosphatidylinositol-3,4-biphosphate, focal, activation, nonreceptor, tyrosine, kinase, Src assembly, invadopodia, phosphatidylinositol-3,4-biphosphate, activation, nonreceptor tyrosine kinase, Src assembly, invadopodia, phosphatidylinositol-3,4-biphosphate, focal, activation, nonreceptor, tyrosine, kinase, Src
1359	Varenicline monotherapy is more effective after 12 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion. varenicline, monotherapy, effectiveness, nicotine, replacement, therapies, bupropion, 12, weeks varenicline, monotherapy, effectiveness, 12 weeks, nicotine replacement, bupropion, smoking cessation varenicline, monotherapy, effectiveness, 12 weeks, nicotine replacement, bupropion, smoking cessation varenicline, monotherapy, effectiveness, nicotine, replacement, therapies, comparison, duration, 12 weeks, bupropion varenicline, monotherapy, effectiveness, 12 weeks, nicotine replacement, bupropion, smoking cessation
137	Asymptomatic visual impairment screening in elderly populations does not lead to improved vision. asymptomatic, visual, impairment, screening, elderly, populations, vision, outcomes asymptomatic, visual, impairment, screening, elderly, populations, vision, improvement asymptomatic, visual, impairment, screening, elderly, populations, improved, vision asymptomatic, visual, impairment, screening, elderly, populations, improved, vision asymptomatic, visual, impairment, screening, elderly, populations, vision, outcomes
1232	The minor G allele of FOXO3 is related to more severe symptoms of Crohn's Disease. FOXO3,G allele,Crohn's Disease,symptomsseverity FOXO3,G allele,Crohn's Disease,symptoms,genetics,molecular biology,inflammation FOXO3,G allele,Crohn's Disease,symptoms,genetics,molecular biology,inflammation FOXO3,G allele,Crohn's Disease,symptoms,genetics,molecular biology,inflammation FOXO3,G allele,Crohn's Disease,symptomsseverity
811	Mutant mice lacking SVCT2 have greatly increased ascorbic acid levels in both brain and adrenals. mutant,mice,SVCT2,ascorbicacid,brain,adrenals Mutant,mice,SVCT2,ascorbicacid,brain,adrenals,vitaminC,synthesis,microcephaly mutant,mice,SVCT2,ascorbic acid,brain,adrenals mutant,mice,SVCT2,ascorbicacid,brain,adrenals Mutant,mice,SVCT2,ascorbic acid,brain,adrenals
814	Mutations in G-Beta protein GNB2 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway. Mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,subunits,AKT,activation Mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,AKT,activation mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,subunits,AKT,activation Mutations,G-Beta,GNB2,cancers,loss,interaction,G-alpha,AKT,activation mutations,G-Beta,GNB2,cancers,G-alpha,AKT,pathway,interaction,activation
936	Peroxynitrite is required for nitration of TCR/CD8. Peroxynitrite,nitration,TCR,CD8,T-cell,retrieval,biochemistry,molecularbiology,immuneresponse Peroxynitrite,nitration,TCR,CD8,T-cell,retrievalKeywords Peroxynitrite,nitration,TCR,CD8,T cell receptor Peroxynitrite,nitration,TCR,CD8,immune response,T-cell Peroxynitrite,nitration,TCR,CD8,T-cell,retrieval,biochemistry,immunology,molecularbiology
36	A deficiency of vitamin B12 increases blood levels of homocysteine. vitamin B12, deficiency, homocysteine, blood levels vitamin B12, deficiency, homocysteine, blood levels vitamin B12, deficiency, homocysteine, blood levels vitamin,B12,homocysteine,blood,deficiency vitamin B12, deficiency, homocysteine, blood levels
1132	TCR/CD3 microdomains are a required to induce the immunologic synapse to activate T cells. TCR, CD3, microdomains, immunologic synapse, T cells, activation TCR, CD3, microdomains, immunologic synapse, T cells, activation TCR, CD3, microdomains, immunologic synapse, T cells TCR, CD3, microdomains, immunologic synapse, T cells TCR, CD3, microdomains, immunologic synapse, T cells, activation
1130	T regulatory cells (tTregs) lacking αvβ8 are more adept at suppressing pathogenic T-cell responses during active inflammation. T-regulatory-cells,TTregs,αvβ8-integrin,suppression,pathogenic-T-cells,inflammation Treg, tTregs, αvβ8, suppression, inflammation, immune regulation Treg, tTregs, alpha_v_beta_8, inflammation, immune suppression, T-cell response Treg, tTregs, alpha-v beta-8, inflammation, suppress, pathogenic T-cells Treg, tTregs, αvβ8, inflammation, suppression, pathogenic, T-cells
380	Enhanced early production of inflammatory chemokines improves viral control in the lung. enhanced, early, production, inflammatory, chemokines, viral, control, lung enhanced, early, production, inflammatory, chemokines, viral, control, lung Enhanced, early, production, inflammatory, chemokines, viral, control, lung Enhanced, early, production, inflammatory, chemokines, viral, control, lung Enhanced, early, production, inflammatory, chemokines, viral, control, lung
1370	Vitamin D deficiency is unrelated to birth weight. Vitamin D, deficiency, birth weight, unrelated, pregnancy, nutrition, infants vitamin D, deficiency, birth weight, unrelated, pregnancy, nutrition, fetal development vitamin D, deficiency, birth weight, unrelated Vitamin D, deficiency, birth weight, unrelated, pregnancy, neonatal, nutrition Vitamin D, deficiency, birth weight, unrelated, pregnancy, nutrition, infants
261	Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO. Chronic,aerobicexercise,endothelialfunction,vasodilation,NO,mechanisms Chronic,aerobic,exercise,endothelial,function,vasodilating,mechanisms,NO,nitric,oxygen,pulse,VASODILATION,ENDOTHELIAL Dysfunction Chronic,aerobicexercise,endothelialfunction,vasodilation,NO,mechanisms Chronic,aerobic,exercise,endothelial,function,vasodilating,mechanisms,NO chronic,aerobicexercise,endothelialfunction,vasodilation,NO,mechanisms
141	Auditory entrainment is strengthened when people see congruent visual and auditory information. AuditoryEntrainment, VisualAids, CongruentInformation, PerceptionEnhancement auditory,entrainment,visual,audio,synchronization,congruence,cognition,sensory,integration auditory,entrainment,visual,audio,synchronization,congruence,cognition,sensory,integration AuditoryEntrainment, VisualInformation, Congruence, Perception, Synchronization, CognitiveProcessing auditory,entrainment,visual,congruent,information,ppl,synchronized
142	Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies. autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies mesenchymal stem cells, autologous transplantation, opportunistic infections, anti-interleukin-2, induction therapy autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin, receptor, antibodies
384	Epidemiological disease burden from noncommunicable diseases is more prevalent in low economic settings. Epidemiology, Noncommunicable, Diseases, Economic, Settings, Burden Epidemiology, Disease Burden, Noncommunicable Diseases, Low Income, Prevalence Epidemiology, Disease burden, Noncommunicable diseases, Low income, Economic settings Epidemiology, Noncommunicable, Disease, Burden, Low, Economic, Settings Epidemiology, Disease burden, Noncommunicable diseases, Low income, Economic settings
143	Autologous transplantation of mesenchymal stem cells causes fewer opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies. autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies mesenchymal, stem, cells, autologous, transplantation, opportunistic, infections, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, opportunistic, infections, induction, therapy, anti-interleukin-2, receptor, antibodies
385	Epigenetic modulating agents (EMAs) modulate antitumor immune response in a cancer model system. Epigenetics, modulating agents, antitumor, immune response, cancer model, treatment Epigenetics, modulating agents, antitumor, immune response, cancer model, immune modulation, epigenetic therapy Epigenetics,modulating,agents,antitumor,immune,response,cancer,model/system Epigenetics,modulating,agents,antitumor,immune,response,cancer,model,system Epigenetic, modulating, agents, antitumor, immune, response, cancer, model, system
386	Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations. errors, peripheral, IV, drug, administration, bolus, multiple, step, medicine, preparation errors, peripheral, IV, drug, administration, bolus, multiple-step, medicine, preparation errors, peripheral, IV, drug, administration, bolus, multiple-step, medicine, preparation errors, peripheral, IV, drug, administration, bolus, multiple-step, medicine, preparation errors, peripheral, IV, drug, administration, bolus, multiple-step, medicine, preparation
1368	Vitamin D deficiency effects the term of delivery. Vitamin D, deficiency, pregnancy, delivery, term, childbirth, maternal health Vitamin D, deficiency, pregnancy, delivery, term, maternal, fetal, health, outcome Vitamin D, deficiency, pregnancy, delivery, childbirth, prenatal, health, fetus, immune system, bone development Vitamin,D,deficiency,effects,pregnancy,outcome,delivery,term,birth,prenatal,health,growth,immunity Vitamin D, deficiency, pregnancy, delivery, term, maternal health
146	Autologous transplantation of mesenchymal stem cells has lower rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies. autologous, transplantation, mesenchymal, stem, cells, rejection, induction, therapy, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem cells, rejection, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, lower, rates, rejection, induction, therapy, anti-interleukin-2, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, lower, rates, rejection, induction, therapy, anti-interleukin, receptor, antibodies autologous, transplantation, mesenchymal, stem, cells, rejection, induction, therapy, anti-interleukin, receptor, antibodies
388	Ethanol stress decreases the expression of IBP in bacteria. Ethanol, stress, expression, IBP, bacteria Ethanol, stress, bacterial, protein, expression, IBP Ethanol, stress, expression, IBP, bacteria Ethanol, stress, bacterial, expression, IBP Ethanol, stress, expression, IBP, bacteria
268	Cold exposure increases BAT recruitment. Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,metabolism,fat burning,energy expenditure cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,metabolism,fat,energy expenditure Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,hypothalamus,energy metabolism,fatigue,resistance thermogenesis Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,energy metabolism cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,energy metabolism,adipocytes,fat metabolism
1245	The one-child policy has been successful in lowering population growth. one-child,policy,successful,population,growth,retrieval,query one-child,policy,successful,population,growth,China,retrieval,query one-child,policy,successful,population,growth,China,reproduction,control,effectiveness one-child,policy,successful,population,growth,China,reproductive,control, demographics one-child,policy,successful,population,growth,China,reproduction,limitation,birth,rules,population-control
148	Autophagy declines in aged organisms. autophagy, aging, senescence, cellular degradation, protein turnover, lysosomes, lifespan, mitochondrial function, gene expression, stress response autophagy, aging, senescence, cellular, metabolism, degradation, lifespan, biomarkers, mitochondrial, regulation autophagy, aging, senescence, mitochondria, lysosomes, ubiquitin, proteasome, starvation, fasting, lifespan, cellular, homeostasis, senolytics autophagy, aging, senescence, lifespan, cellular, degradation, lysosome, mitochondria, metabolism, senile autophagy, aging, senescence, cellular degradation, protein turnover, lifespan, mitochondrial function, senile plaques, lysosomes, autophagosomes
269	Cold exposure reduces BAT recruitment. Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,energy metabolism,fatigue,thermoregulation,hypothermia Cold exposure,BAT,brown adipose tissue,research,thermogenesis,metabolism,weight loss,human,animal experiment Cold exposure,BAT,brown adipose tissue,recruitment,thermogenesis,body fat,mouse,experiment,energy expenditure,fat metabolism,winter cold cold exposure,BAT,brown adipose tissue,thermogenesis,energy metabolism,fat burning,cryo-adaptation,hypothermia,preservation,activation,temperature regulation cold exposure,BAT,brown adipose tissue,thermogenesis,energy metabolism,temperature regulation,fatigue,resistance exercise,non-shivering thermogenesis,adiponectin,leptin
820	N-terminal cleavage increases success identifying transcription start sites. N-terminal, cleavage, transcription, start, sites, proteomics, sequencing, bioinformatics N-terminal, cleavage, transcription, start, sites, identification, proteomics, bioinformatics N-terminal, cleavage, transcription, start, sites, identification, proteomics, RNA, processing N-terminal,cleavage,transcription,start,sites,retention,sequence,identification,proteomics,motif,promoter,detection,analysis,genomics,nucleotide,expression,splicevariants N-terminal,cleavage,transcription,start,sites,identification,molecular,biology,genomics,RNA,promoter,detection,analysis,biotechnology
700	Localization of PIN1 in the Arabidopsis embryo does not require VPS9a Localization,PIN1,Arabidopsis,embryo,VPS9a,retrieval,molecular biology植物细胞生物学 PIN1, localization, Arabidopsis, embryo, VPS9a, protein trafficking, cellular localization, plant biology PIN1, localization, Arabidopsis, embryo, VPS9a, protein trafficking PIN1, localization, Arabidopsis, embryo, VPS9a, protein trafficking, plant cell biology, endomembrane system, vesicle transport Localization,PIN1,Arabidopsis,embryo,VPS9a,retrieval,require,protein trafficking,cell biology,molecular biology,plant science
821	N-terminal cleavage reduces success identifying transcription start sites. N-terminal, cleavage, transcription, start, sites, proteomics, sequencing, RNA, processing N-terminal, cleavage, transcription, start, sites, identification, proteomics, RNA, sequencing N-terminal,cleavage,transcription,start,sites,identification,success,factors,affecting,mRNA,processing N-terminal,cleavage,transcription,start,sites,identification,reduces,improve,retrieval,promoter,sequence,genomics,bioinformatics N-terminal, cleavage, transcription, start, sites, identification, proteomics, RNA, processing, sequencing, bioinformatics
702	Localization of PIN1 in the roots of Arabidopsis does not require VPS9a Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval,Molecular Biology,Plant Science,Localization Assays Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval,require,localization Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval,requirement Localization,PIN1,roots,Arabidopsis,VPS9a,retrieval,require
823	N348I mutations cause resistance to zidovudine (AZT). N348I, mutations, zidovudine, AZT, resistance N348I, mutations, zidovudine, AZT, resistance N348I, mutations, zidovudine, AZT, resistance N348I,mutations,zidovudine,AZT,resistance,HIV N348I,mutations,zidovudine,AZT,resistance,HIV
42	A high microerythrocyte count raises vulnerability to severe anemia in homozygous alpha (+)- thalassemia trait subjects. high microerythrocyte count, vulnerability, severe anemia, homozygous, alpha (+)-thalassemia, trait microerythrocyte,count,anemia,homozygous,alpha,+,-,thalassemia,trait,vulnerability microerythrocyte,count,severe,anemia,homozygous,thalassemia,alpha,+,-,trait,vulnerability microerythrocyte,count,anemia,homozygous,thalassemia,alpha,+,-,trait,vulnerability high microerythrocyte count, severe anemia, homozygous alpha (+)-thalassemia, vulnerability
48	A total of 1,000 people in the UK are asymptomatic carriers of vCJD infection. asymptomatic, vCJD, infection, UK, 1000, people vCJD, asymptomatic, carriers, UK, infection asymptomatic, vCJD, infection, UK, people UK,vCJD,asymptomatic,carriers,infection,population UK, vCJD, asymptomatic, carriers
49	ADAR1 binds to Dicer to cleave pre-miRNA. ADAR1,Dicer,pre-miRNA,cleavage,microRNAProcessing ADAR1,Dicer,pre-miRNA,cleavage,microRNAprocessing ADAR1,Dicer,pre-miRNA,cleavage,microRNAprocessing ADAR1,Dicer,pre-miRNA,cleavage,binding,microRNAprocessing ADAR1,Dicer,pre-miRNA,cleavage,microRNA_processing,RNA_editing
1385	cSMAC formation enhances weak ligand signalling. cSMAC, protein, signaling, pathway, ligand, interaction, biology, receptor, activation, mechanism cSMAC, protein, ligand, signaling, interaction, biology, receptor, activation, mechanism cSMAC, protein, signaling, ligand, interaction, receptor, activation, biology, cell, regulation cSMAC, signaling, ligands, protein_complexes, cell_signaling, weak_interactions, biological_processes cSMAC, formation, weak, ligand, signalling, protein, biology, receptors, interaction, mechanism
1021	Rapid up-regulation and higher basal expression of interferon-induced genes reduce survival of granule cell neurons that are infected by West Nile virus. Rapid, up-regulation, interferon, genes, basal, expression, granule, cell, neurons, infected, West, Nile, virus, survival Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, neuron, infected, West, Nile, virus
1020	Rapid up-regulation and higher basal expression of interferon-induced genes increase survival of granule cell neurons that are infected by West Nile virus. Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West, Nile, virus Rapid, up-regulation, interferon, genes, survival, granule, neurons, infected, West Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, infected, West Nile, virus Rapid, up-regulation, interferon-induced, genes, survival, granule, cell, neurons, West, Nile, virus Rapid, up-regulation, interferon, genes, basal, expression, survival, granule, cell, neurons, infected, West, Nile, virus
1262	The repair of Cas9-induced double strand breaks in human DNA is error-prone. Cas9, doublestrandbreaks, repair, humanDNA, errorprone Cas9, doublestrandbreaks, humanDNA, repair, errorprone, genomeediting Cas9, doublestrandbreaks, humanDNA, repair, errorprone Cas9, doublestrandbreaks, DNArepair, errorprone, humancells Cas9, doublestrandbreaks, humanDNA, repair, errorprone, geneediting
1140	Taking 400mg of α-tocopheryl acetate helps to prevent prostate cancer. α-tocopheryl acetate,male,fat-soluble,vitamin,E,cancer,prostate,prevention,dosage,400mg α-tocopheryl,acetate,megadoses,prostate,cancer,antioxidant,vitamin,E,preventive,therapy,dose α-tocopheryl,acetate,male,cancer,prostate,vitamin,E,dose,prevention α-tocopheryl,acetate,male,cancer,prostate,vitamin,E,dose,prevention α-tocopheryl,acetate,megadoses,prostate,cancer,antioxidant,vitamin,E,prevention,dosage
1382	aPKCz causes tumour enhancement by affecting glutamine metabolism. aPKCz,tumour,glutamine,metabolism,cancer,pathway,signaling,synthesis,metabolism,affect,enhancement aPKCz,tumour,glutamine,metabolism,cancer,growth,signaling,cellular,proliferation aPKCz,tumour,enhancement,glutamine,metabolism,cancerbiosignaling,MET pathway, Oncogenesis aPKCz,tumour,glutamine,metabolism,cancer,enhancement aPKCz,tumour,glutamine,metabolism,cancer,retrieval,biochemistry,signal,transduction,gene,expression,proliferation,survival
274	Combination nicotine replacement therapies with varenicline or bupropion lead to significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy. nicotine, replacement, therapies, varenicline, bupropion, abstinence, rates, 52, weeks, monotherapy nicotine, replacement, therapies, varenicline, bupropion, abstinence, rates, long-term, 52, weeks, monotherapy nicotine,replacement,therapies,varenicline,bupropion,abstinence,long-term,treatment,smoking,cessation,effectiveness,clinical,trials,studies nicotine,replacement,therapies,varenicline,bupropion,abstinence,long-term,recovery,study,weeks,treatment,effectiveness,smoking,cessation,therapy,clinical,trials nicotine,replacement,therapies,varenicline,bupropion,abstinence,long-term,treatment,effectiveness,52,weeks,smoking,cessation,studies,research,population,clinical,trials,combinations,therapy,comparison,success,rates,quit,smoking,cessation,stopping,addiction,medication,stop,quitting,health,behavior,challenges,benefits,side,effects,pharmacotherapy,tobacco,control,population,surveys,meta-analysis,analysis,review,smokers,cessation,program,study,pilot,
1019	Rapid phosphotransfer rates govern fidelity in two component systems phosphotransfer, fidelity, two-component systems, signal transduction, bacterial regulation, kinases, response regulators Rapid, phosphotransfer, fidelity, two, component, systems, bacterial, signal, transduction, regulation, protein, phosphorylation Rapid, phosphotransfer, fidelity, two, component, systems, signaling, bacteria, regulation, phosphorylation Rapid, phosphotransfer, rates, fidelity, two, component, systems, signaling, bacteria, regulation, phosphorylation Rapid, phosphotransfer, fidelity, two, component, systems, signal, transduction, bacteria, phosphorylation
275	Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is effective at treating KRAS mutant tumors. phosphatidylinositide, 3-kinase, MEK, KRAS, tumors, combination, treatment phosphatidylinositide, 3-kinase, MEK, KRAS, tumor, treatment, inhibitors phosphatidylinositide, 3-kinase, MEK, KRAS, tumor, treatment, inhibitor phosphatidylinositide, 3-kinase, MEK, KRAS, tumor, treatment, inhibitors phosphatidylinositide, 3-kinase, MEK, KRAS, tumor, treatment, inhibitor, combination, therapy
1259	The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up. breast cancer,tamoxifen,metabolism,genetic make-up,treatment outcome breast cancer,tamoxifen,metabolism,gene,patient,outcome,genetic make-up breast cancer,tamoxifen,metabolism,genetic make-up,treatment outcome breast cancer,tamoxifen,metabolism,genetic make-up,treatment outcome breast cancer,tamoxifen,metabolism,genetic make-up,treatment outcome
1137	TNFAIP3 is a tumor suppressor in glioblastoma. TNFAIP3,glioblastoma,tumor suppressor,molecular biology,cancer research,genetics,RNF5,miR-146a/pathway TNFAIP3,tumor,suppressor,glioblastoma,cancer,molecular,biology,genetics,prognosis,pathway,disease,expression,therapy,mechanism,study,research,network,interaction,mutation,signaling,clinical,analysis,association,validation,screening,screening,diagnosis,treatment,proteomics,omics,genomics,microarray,mRNA,protein,marker,predictor,regulation,activation,inhibition,interaction,correlation,association,validation,biomarker,expression,analysis,identification,evaluation,characterization,investigation,comparison TNFAIP3,tumor,suppressor,glioblastoma,cancer,genetics,molecular,biology,pathway,expression,mutation,prognosis,treatment,immunology,inflammation TNFAIP3,tumor,suppressor,glioblastoma,cancer,genetics,molecular,biochemistry,pathway,expression,protein,biological,cellular,therapy,biology,microarray,analysis,study,research,neuroscience,clinical,signaling,immune,inflammation TNFAIP3,glioblastoma,tumor,suppressor,microRNA,prognosis,expression,cancer,genetics,therapy
1379	Women with a higher birth weight are more likely to develop breast cancer later in life. birthweight, breastcancer, women, development, laterlife birthweight, breastcancer, women, development, laterlife birthweight, breastcancer, women, likelihood, adulthood birth weight, breast cancer, women, likelihood, development birth weight, breast cancer, women, likelihood, development
399	Exposure to fine particulate air pollution is relate to anxiety prevalence. exposure,fine,particulate,pollution,anxiety,prevalence,health,environment,air quality exposure,fine,particulate,air,pollution,anxiety,prevalence,health,effects,environmental,mental,healthoutcomes exposure,fine,particulate,air,pollution,anxiety,prevalence,health,effect,environmental,risk,factor,study,association,mental,illness,population,study,statistics,impact fine particulate matter, air pollution, anxiety, prevalence, epidemiology, health effects, environmental exposure fine particulate matter, air pollution, anxiety, prevalence, epidemiology, health effects, environmental exposure
279	Commelina yellow mottle virus' (ComYMV) genome consists of 7489 baise pairs. Commelina黄斑病毒, ComYMV, 基因组, 7489, 基因对, RNA病毒 Commelina_yellow_mottle_virus,Baise_pairs,Genome_length Commelina, yellow, mottle, virus, ComYMV, genome, base, pairs Commelina, yellow, mottle, virus, ComYMV, genome, base, pairs Commelinayellowmottlevirus, ComYMV, genome, basepairs, DNA, RNA, plantvirus
1014	Rapamycin decreases the concentration of triacylglycerols in fruit flies. Rapamycin, triacylglycerols, fruit flies, longevity, metabolism, nutrient sensing, TOR, diet restriction, lifespan, lipid, metabolic syndrome, aging, gerontology Rapamycin, triacylglycerols, fruit flies, lifespan, metabolism, nutrition, aging, signaling, adipose tissue, diet, genetic manipulation, lipidomics Rapamycin, triacylglycerols, fruit flies, lipid metabolism, longevity, mTOR, diet, intervention, metabolic disorders Rapamycin, triacylglycerols, fruit flies, lifespan, metabolism, nutrition, aging, diet, gene expression, insulin signaling, longevity Rapamycin, triacylglycerols, fruit flies, lipid metabolism, longevity, aging, metabolic syndrome
830	NF2 (Merlin) causes phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila by activating LATS1/2 kinases. NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, LATS1, LATS2, Drosophila NF2, Merlin, phosphorylation, YAP, cytoplasmic sequestration, LATS1/2, Drosophila NF2, Merlin, phosphorylation, YAP, cytoplasmic sequestration, LATS1/2, Drosophila, kinase NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, LATS1/2, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, LATS1/2, Drosophila
831	NF2 (Merlin) prevents phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila. NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila NF2, Merlin, YAP, phosphorylation, cytoplasmic sequestration, Drosophila
1012	Radioiodine treatment of non-toxic multinodular goitre reduces thyroid volume. Radioiodine,treatment,non-toxic,multinodular goitre,thyroid volume,reduction,thyroidectomy,management,endocrinetherapy Radioiodine,treatment,non-toxic,multinodular goitre,thyroid volume,reduction Radioiodine,treatment,non-toxic,multinodular,goitre,thyroid,volume,reduction Radioiodine,treatment,non-toxic,multinodular goitre,thyroid volume,reduction,thyroidectomy替代方案 Radioiodine,treatment,non-toxic,multinodular goitre,thyroid volume,reduction
832	NFAT4 activation requires IP3R-mediated Ca2+ mobilization. NFAT4, activation, IP3R, Ca2+, mobilization NFAT4, activation, IP3R, Ca2+, mobilization, signaling, calcium, regulation, transcription, factor NFAT4, activation, IP3R, Ca2+, mobilization, signaling, pathway, calcium, regulation, transcription, factor, immune response, gene expression NFAT4, activation, IP3R, Ca2+, mobilization, signaling, pathway, calcium, regulation, transcription, factor NFAT4, activation, IP3R, Ca2+, mobilization
834	NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates. NOX2, peroxynitrite, nitrogen intermediates, oxidative stress, signaling pathways NOX2, peroxynitrite, nitrogen intermediates, pathways NOX2, peroxynitrite, nitrogen intermediates, pathway, generation NOX2, peroxynitrite, nitrogen intermediates, pathway, generation NOX2, peroxynitrite, nitrogen intermediates, pathway, generation
956	Pleiotropic coupling of GLP-1R to intracellular effectors promotes distinct profiles of cellular signaling. GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, distinct, profiles GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, distinct, profiles GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, coupling GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, distinct, profiles GLP-1R, pleiotropy, intracellular, effectors, cellular, signaling, coupling, profiles
50	AIRE is expressed in some skin tumors. AIRE,skin tumors,expression,molecular markers,cancer biology,immunology,tumor microenvironment AIRE,tumors,skin,cancer,expression,gene AIRE,tumors,skin,cancer,gene,expression,immunology,molecular biology AIRE,tumors,skin,cancer,gene,expression AIRE,tumors,skin,cancer,gene,expression,immunology,molecularbiology
715	Low expression of miR7a does represses target genes and exerts a biological function in ovaries. miR7a, low expression, repression, target genes, biological function, ovaries miR7a, low expression, target genes, biological function, ovaries miR7a, low expression, target genes, biological function, ovaries miR7a, low expression, target genes, biological function, ovaries miR7a, low expression, target genes, biological function, ovaries
957	Podocytes are motile and migrate in the presence of injury. Podocytes,motility,injury,migration,glomerular,damage,renal,tissue repair,specialized cells Podocytes,motility,injury,migration,renal,tissue repair,damage response Podocytes,motility,injury,migration,renal,tissue repair,cell behavior Podocytes,motility,injury,migration,renal,tissue repair,differentiation Podocytes,motility,injury,migration,glomerular,damage,renal,tissue repair
51	ALDH1 expression is associated with better breast cancer outcomes. ALDH1, breast cancer, prognosis, outcome, biomarker ALDH1, breast cancer, outcomes, expression, prognosis ALDH1, breast cancer, outcomes, expression, prognosis ALDH1, breast cancer, prognosis, outcome, biomarker ALDH1, breast cancer, outcome, prognosis, biomarker, expression
716	Low expression of miR7a exerts a biological function in testis. miR7a, low expression, testis, biological function miR7a, low expression, biological function, testis miR7a, testis, low expression, biological function miR7a, testis, low expression, biological function miR7a, testis, low expression, biological function
837	NR5A2 is important in development of endometrial tissues. NR5A2,endometrial,tissues,development,genes,molecularbiology,endometrium,fertility,reproductivehealth NR5A2,endometrial,tissues,development,gene,function,biology,reproductive,health,molecular,endothelial NR5A2,endometrial,tissues,development,biology,research,molecular,genes,gene function NR5A2, endometrial tissue, development, gene, transcription factor NR5A2,endometrial,tissues,development,biology,genes,retrieval,molecular,expression,female,reproductive健康医学领域相关关键词可能不准确，应为：reproductive,gene,endothelial,cytokines,signaling,regulation,expression,mRNA,transcription因子相关的关键词可能包括：transcription,factor,steroid,inducible,regulator,expression,upregulation,downregulation,signaling pathway
53	ALDH1 expression is associated with poorer prognosis in breast cancer. ALDH1, breast cancer, prognosis, gene expression ALDH1, breast cancer, prognosis, expression, biomarker, oncology, tumor, survival, gene, pathology ALDH1, breast cancer, prognosis, biomarker, oncology, tumor marker, survival, gene expression ALDH1, breast cancer, prognosis, expression, biomarker ALDH1, breast cancer, prognosis, expression, biomarker
718	Low nucleosome occupancy correlates with low methylation levels across species. nucleosome, occupancy, methylation, species, correlation, epigenetics nucleosome, occupancy, methylation, species, epigenetics, genome, chromatin, DNA, correlation, evolutionary low,nucleosome,occupancy,methylation,species,genetics,chromatin,eukaryotes,bioinformatics,binding,patterns nucleosome, occupancy, methylation, species, epigenetics, genome, histone, DNA, evolution, chromatin nucleosome, occupancy, methylation, species, epigenetics, chromatin, DNA, histone
839	Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles. Nanoparticles,aptamers,lipid,nanoparticles,cell targeting,specific cell types Nanoparticles, aptamers, lipid nanoparticles, targeted delivery, cell types Nanoparticles, aptamers, lipid nanoparticles, targeted delivery, cell types Nanoparticles,aptamers,lipid,nanoparticles,targeting,cell,types Nanoparticles, Aptamers, Lipid nanoparticles, Targeted delivery, Specific cell types
54	AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs. AMP-activated protein kinase, AMPK, inflammation, fibrosis, lungs, activation, signaling, pathway, metabolism, therapy, regulation AMP-activated protein kinase, AMPK, inflammation, fibrosis, lungs, activation, signaling, metabolic stress, oxidative stress, mechanistic target of rapamycin complex 1, mTORC1, autophagy, cytokines, collagen deposition, lung injury, chronic obstructive pulmonary disease, COPD AMP-activated protein kinase, AMPK, inflammation, fibrosis, lungs, activation, signaling, metabolic, stress, response AMP-activated protein kinase, activation, inflammation, fibrosis, lungs AMP-activated protein kinase, activation, inflammation, fibrosis, lungs
56	APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation causing GABA neuron degeneration. APOE4,iPSC,neurons,AlphaBeta,tau phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration
57	APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation, delaying GABA neuron degeneration. APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration APOE4,iPSC,networks,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration,research,genetics,biomarkers,molecular biology,stem cells,neuroscience,clinical applications APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration APOE4,iPSC,neurons,AlphaBeta,tau,phosphorylation,GABA,degeneration APOE4,iPSC,delay,GABA,tau,phosphorylation,AlphaBeta,neurons,expression
1274	The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) carries toxic effector proteins. tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli tip, inner tube, toxic, type VI secretion system, T6SS, antibacterial, effector, proteins, Escherichia coli, E. coli
1395	p16INK4A accumulation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs). p16INK4A, accumulation, abnormal, wound, response, microinvasive, step, advanced, Oral, Potentially, Malignant, Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, step, advanced, Oral, Potentially, Malignant, Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, advanced, Oral, Potentially, Malignant, Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, advanced, Oral, Potentially, Malignant, Lesions, OPMLs p16INK4A, accumulation, abnormal, wound, response, microinvasive, advanced, Oral, Potentially, Malignant, Lesions, OPMLs
1273	The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly. kinesin-8, Kip3, sliding activity, bipolar spindle, assembly kinesin-8, Kip3, sliding activity, bipolar spindle, assembly kinesin-8, Kip3, sliding activity, bipolar spindle, assembly kinesin-8, Kip3, sliding activity, bipolar spindle assembly sliding, activity, kinesin-8, Kip3, promotes, bipolar, spindle, assembly
1272	The single flash-evoked ERG b-wave is generated by activity of ON-bipolar cells. flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells flash-evoked, ERG, b-wave, ON-bipolar, cells
1150	Tetraspanin-3 is a causative factor in the development of acute myelogenous leukemia Tetraspanin-3, acute myelogenous leukemia, causative factor, oncology, hematopoiesis, cancer biology, protein function Tetraspanin-3, acute myelogenous leukemia, cancer, biomarker, protein, immune system, oncology, genetics, cell signaling Tetraspanin-3, acute myelogenous leukemia, cancer, biomarker, signaling, protein, hematological malignancy Tetraspanin-3, acute myelogenous leukemia, causative factor, oncology, hematopoiesis, cell signaling, protein expression Tetraspanin-3, acute myelogenous leukemia, causative factor, immune regulation, cancer biomarker, cell signaling
1271	The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI. amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity amyloidosis, cardiac involvement, MRI, late gadolinium enhancement, transmurality, severity
1270	The risk of male prisoners harming themselves is ten times that of female prisoners. male prisoners, self harm, female prisoners, risk, ratio male prisoners, self harm, female prisoners, risk, ratio male prisoners, self harm, female prisoners, risk, statistics male prisoners, self harm, female prisoners, risk, statistics male prisoners, self harm, female prisoners, risk, statistics
163	Bariatric surgery has a positive impact on mental health. bariatric,surgery,mental,health,improvement,effect,psychological,wellness,obesity,treatment bariatric,surgery,mental,health,improvement,effect,patient,outcome,weight_loss,surgery_morbid_obesity Bariatric,surgery,mental,health,positive,impact,obesity,weight_loss,surgery,outcomes,surgical,treatment,psychological,benefits bariatric,surgery,mental,health,impact,obesity,psychological,outcomes,treatment bariatric,surgery,mental,health,impact,obesity,psychological,outcomes,recovery,quality,life
1029	Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes. IL-2, regulatory T cells, responsiveness, autoimmune diseases, Type 1 Diabetes, immune regulation regulatory T cells, interleukin-2, responsiveness, autoimmune diseases, Type 1 Diabetes, immune regulation Interleukin-2, Regulatory T cells, Responsiveness, Autoimmune diseases, Type 1 Diabetes, Immune response, Inflammation, Immunosuppression interleukin-2, regulatory T cells, responsiveness, autoimmune diseases, Type 1 Diabetes, immune tolerance, inflammation, cytokines, immunosuppression, Tregs, pathogenesis interleukin-2, regulatory T cells, responsiveness, autoimmune diseases, Type 1 Diabetes, resistance
960	Polymeal nutrition reduces cardiovascular mortality. Polymeal,nutrition,cardiovascular,mortality,health,diet,effectiveness,benefits,food combination Polymeal,nutrition,cardiovascular,mortality,health,diet,effectiveness,benefits,cardiovascular disease Polymeal,nutrition,cardiovascular,mortality,health,diet,benefits,potassium,sodium,fat,intake,study,research,analysis Polymeal,nutrition,cardiovascular,mortality,health,diets,foodcombination,effectiveness,cardiovasculardisease-prevention polymeal,nutrition,cardiovascular,mortality,diets,health,polymeals,foodcombination
1389	mTORC2 regulates intracellular cysteine levels through xCT inhibition. mTORC2,cysteine,xCT,regulation,inhibition,biochemistry,molecular biology,cell signaling mTORC2,xCT,intracellular,cysteine,regulation, inhibition, signaling,pathway,biomolecule,proteins,metabolism mTORC2,xCT,cysteine,regulation,internal,biochemistry,molecular biology,endocytosis,signal transduction mTORC2,xCT,cysteine,regulation,internuclear,signaling,mechanism,biochemistry,cellularbiology mTORC2,cysteine,xCT,regulation,cellular,dynamics,inhibition,biochemistry,molecularbiology,signaling,pathway
1146	Teaching hospitals do not provide better care than non-teaching hospitals. teaching hospitals,care quality,non-teaching hospitals,medical education,research institutions,hospital effectiveness,patient outcomes teaching hospitals,care quality,non-teaching hospitals,medical education,inpatient care,outcome comparison,research facilities,patient satisfaction teaching hospitals,care quality,non-teaching hospitals,medical education,patient outcomes,hospital type,healthcare effectiveness teaching hospitals, non-teaching hospitals, patient care quality, medical education, healthcare outcomes teaching hospitals,care quality,non-teaching hospitals,medical education,patient outcomes,hospital type,healthcare effectiveness
1024	Recurrent mutations occur frequently within CTCF anchor sites adjacent to oncogenes. recurrentmutations,ctcfanchorites,oncogenes,molecularbiology,cancergenetics,genomicvariants,transcriptionfactors,geneticmutationsdna recurrentmutations,CTCFanchorites,oncogenes,genetics,molecularbiology,cancergenetics,mutationrates,genomicvariants recurrent,mutations,CTCF,anchor,sites,oncogenes,frequency recurrentmutations,ctcfanchorites,oncogenes,genomicaberrations,cancerbiology,moleculargenetics,somaticmutationsdna recurrent,mutations,CTCF,anchor,sites,oncogenes,frequency,bioinformatics,molecular,genetics,cancer,promoter,transcription,fusion,gene regulation,microbial,genome stability,variant,mutation analysis,genomicvariants,transcription factor binding sites,genetic predisposition,DNA methylation,chromatin remodeling,tumorigenesis,genetic variants,biomarker,genomic instability,transcriptional regulation,genomics,epigenetics,nucleosome positioning,chromatin interactions,genetic variation,mutation detection,variant calling,genetic markers,mutation profiling,genetic
1266	The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer. breast cancer, parous women, placental weight, pregnancies, premenopausal, risk, association breast_cancer, parous_women, placental_weight, pregnancies, premenopausal, risk_factors breast cancer, parous women, placental weight, pregnancies, premenopausal, risk因素, 胎盘重量, 产次, 乳腺癌风险, 前激素期 breast cancer, parous women, placental weight, pregnancies, premenopausal, risk因素, 胎盘重量, 哺乳期女性, 乳腺癌风险 breast cancer, parous women, placental weight, pregnancies, premenopausal, risk factors
721	Lupus-prone mice infected with curliproducing bacteria have higher autoantibody titers compared to controls. Lupus, mice, infection, bacteria, autoantibodies, titers, curliproducing Lupus-prone,mice,curliproducing,bacteria,autoantibody,titers,controls Lupus-prone,mice,curliproducing,bacteria,autoantibody,titers,controls Lupus-prone,mice,curliproducing,bacteria,autoantibody,titers,controls Lupus, mice, curliproducing bacteria, autoantibodies, titre, immunology
1144	Taxation of sugar-sweetened beverages had no effect on the incidence rate of type II diabetes in India. taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect,research,policyimpact taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect taxation,sugar-sweetened beverages,incidence,type II diabetes,India,effect
723	Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions. Ly49Q, neutrophil, migration, inflammation, membrane, raft, function Ly49Q, neutrophil, migration, inflammation, membrane raft, functions Ly49Q, neutrophil, migration, inflammation, membrane, raft, functions Ly49Q, neutrophil, migration, inflammation, membrane, raft, functions Ly49Q, neutrophil, migration, inflammation, membrane raft, functions
845	Neutrophil extracellular traps (NETs) are released by ANCA-stimulated neutrophils. Neutrophils, Extracellular, Traps, NETs, ANCA, Stimulated, Inflammation Neutrophils, Extracellular, Traps, NETs, ANCA, Stimulated, Inflammation Neutrophils, Extracellular traps, NETs, ANCA, Stimulated, Release Neutrophil, extracellular, traps, NETs, ANCA, stimulated, neutrophils Neutrophils, Extracellular, Traps, NETs, ANCA, Stimulated, Inflammation
967	Pretreatment with the Arp2/3 inhibitor CK-666 affects lamelliopodia formation. Pretreatment, Arp2/3, inhibitor, CK-666, lamellipodia, formation Pretreatment, Arp2/3, CK-666, inhibition, lamellipodia, cell migration Pretreatment, Arp2/3, inhibitor, CK-666, lamellipodia, formation Pretreatment, Arp2/3, inhibitor, CK-666, lamellipodia, formation Pretreatment, Arp2/3, CK-666, inhibits, lamellipodia, formation
847	New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations. tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic, lesion, penetration, concentration tuberculosis, drugs, necrotic, lesion, penetration, concentration
727	Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts. Ly6C, monocytes, inflammation, capacity, counterparts Ly6C, monocytes, inflammatory capacity, counterparts Ly6C, monocytes, inflammatory, capacity, counterparts Ly6C, monocytes, inflammatory capacity, inflammation, immune cells, counterparts, expression, regulation Ly6C, monocytes, inflammatory capacity, counterparts
728	Ly6C hi monocytes have a lower inflammatory capacity than Ly6C lo monocytes. Ly6C, monocytes, inflammatory, capacity, comparison, immune, cells Ly6C, monocytes, inflammation, capacity, comparison Ly6C, monocytes, inflammation, capacity, comparison Ly6C, monocytes, inflammatory, capacity, differentiation, phenotype Ly6C, monocytes, inflammation, capacity, comparison
729	Lymphadenopathy is observed in knockin mouse lacking the SHP-2 MAPK pathway. Lymphadenopathy, knockin mouse, SHP-2, MAPK pathway Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway Lymphadenopathy,knockin,mouse,SHP-2,MAPK,pathway
1163	The DdrB protein from Deinococcus radiodurans is an alternative SSB. DdrB, protein, Deinococcus radiodurans, alternative, SSB DdrB, protein, Deinococcus radiodurans, alternative, SSB DdrB, protein, Deinococcus radiodurans, alternative, SSB, DNA repair, radiation resistance DdrB, Deinococcus radiodurans, alternative, SSB, protein DdrB, Deinococcus radiodurans, alternative, SSB, protein
1041	Replacement of histone H2A with H2A.Z slows gene activation in yeasts by stabilizing +1 nucleosomes. histone, H2A, H2A.Z, gene, activation, yeasts, nucleosomes, stabilization histone,H2A,H2A.Z,gene,activation,yeasts,nucleosomes,stabilization,chromatin,modification,molecularbiology,DNA,RNA,transcription,regulation,genetics histone,H2A,H2A.Z,geneactivation,yeasts,nucleosomes,stabilization,+1 histone, H2A, H2A.Z, gene activation, yeasts, nucleosomes, stabilization histone,H2A,H2A.Z,gene,activation,yeasts,nucleosomes,stabilization,+1
171	Basophils counteract disease development in patients with systemic lupus erythematosus (SLE). Basophils,SLE,counteract,disease,retrieval Keywords,immune/response,clinical/biology Basophils, Systemic lupus erythematosus, SLE, immune response, inflammation, counteract, disease development Basophils,disease development,Systemic Lupus Erythematosus,SLE,influence,immune response,therapeutic target Basophils, Systemic lupus erythematosus, SLE, immune response, inflammation, counteract, disease development Basophils,SLE,disease,counteract,patients,immuneresponse,inflammation
1282	Therapeutic use of the drug Dapsone to treat pyoderma gangrenous is based on anecdotal evidence. Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence Dapsone, pyoderma gangrenosum, therapeutic, anecdotal, evidence Dapsone, pyoderma gangrenosum, therapeutic, evidence, anecdotal
1281	The ureABIEFGH gene cluster is induced by nickel (II) ion. ureAB gene cluster,nickel induction,microbial genes,mineral tolerance,heavy metal,bioremediation,metallotransferase ureAB gene cluster,nickel (II) ion,induction,microbial genetics,metallomics ureABIEFGH,gene,cluster,nickel(II),ion,induction ureAB gene cluster,nickel (II) ion,induction,microbiology,gene expression,nickel toxicity,Gene regulation ureAB gene cluster,nickel induction,microbial response,nickel (II) ion,gene regulation,Metal tolerance,heavy metal,UreABFGDH,transcription factor,NIC operon
294	Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae. Crossover, hotspots, gene, promoters, Saccharomyces, cerevisiae Crossover, hotspots, gene, promoters, Saccharomyces, cerevisiae Crossover, hotspots, gene, promoters, Saccharomyces cerevisiae Crossover, hotspots, gene, promoters, Saccharomyces, cerevisiae crossover, hotspots, gene, promoters, Saccharomyces cerevisiae
1280	The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG. ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG ureAB gene cluster, urease maturation, UreD, UreH, UreE, UreF, UreG ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG ureABIEFGH,gene,cluster,urease,maturation,proteins,UreD,UreH,UreE,UreF,UreG
295	Crosstalk between dendritic cells (DCs) and innate lymphoid cells (ILCs) is important in the regulation of intestinal homeostasis. dendritic cells,intestinal homeostasis,innate lymphoid cells,crosstalk,regulation dendritic cells,intestinal homeostasis,innate lymphoid cells,crosstalk,regulation dendritic cells,intestinal homeostasis,innate lymphoid cells,crosstalk,regulation dendritic cells, innate lymphoid cells, crosstalk, intestinal homeostasis, immune regulation dendritic cells, innate lymphoid cells, intestinal homeostasis, crosstalk, immune regulation
298	Cytochrome c is released from the mitochondrial intermembrane space to cytosol during apoptosis. Cytochrome, c, mitochondria, intermembrane, space, cytosol, apoptosis, release Cytochrome, c, mitochondrial, intermembrane, space, cytosol, apoptosis Cytochrome, c, mitochondria, intermembrane, space, cytosol, apoptosis Cytochrome, c, mitochondrial, intermembrane, space, cytosol, apoptosis Cytochrome, c, mitochondria, intermembrane, space, cytosol, apoptosis
179	Birth-weight is positively associated with breast cancer. birthweight,breastcancer,association,populationstudy,infant,adult,mortality,riskfactor birthweight,breastcancer,association,prenatal,health,outcome,risk,factors,obstetrics,oncology birthweight,breastcancer,association,prenatal,health,outcome,risk,factor,studies,research birthweight,breastcancer,association,populationstudy,maternalhealth,fetaldevelopment birthweight,breastcancer,association,prenatal,outcome,risk,factors,growth,mortality
971	Primary cervical cancer screening with HPV detection has higher longitudinal sensitivity than conventional cytology to detect cervical intraepithelial neoplasia grade 2. cervical_cancer_screening, HPV_detection, sensitivity, cytology, cervical_intraepithelial_neoplasia, grade_2 cervical_cancer_screening, HPV_detection, longitudinal_sensitivity, cytology, cervical_intraepithelial_neoplasia, grade_2 cervical cancer, screening, HPV, detection, sensitivity, cytology, cervical intraepithelial neoplasia, grade 2 cervical cancer, screening, HPV, detection, sensitivity, cytology, cervical intraepithelial neoplasia, grade 2 cervical cancer, screening, HPV, detection, sensitivity, cytology, cervical intraepithelial neoplasia, grade 2
1279	The treatment of cancer patients with co-IR blockade precipitates adverse autoimmune events. cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune reactions cancer,treatment,co-IR blockade,adverse events,autoimmune
1278	The treatment of cancer patients with co-IR blockade does not cause any adverse autoimmune events. cancer,treatment,co-IR,blockade,adverse,event,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune cancer,treatment,co-IR blockade,adverse events,autoimmune
852	Non-invasive ventilation use should be decreased if there is inadequate response to conventional treatment. non-invasive, ventilation, inadequate, response, conventional, treatment non-invasive, ventilation, inadequate, response, conventional, treatment non-invasive, ventilation, response, conventional, treatment, decrease non-invasive, ventilation, decrease, inadequate, response, conventional, treatment non-invasive, ventilation, decrease, inadequate, response, conventional, treatment
975	Primary pro-inflammatory cytokines induce secondary pro- and anti-inflammatory mediators. Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory Primary,cytokines,pro-inflammatory,secondary,mediators,anti-inflammatory
613	Increased microtubule acetylation repairs LRRK2 Roc-COR domain mutation induced locomotor deficits. microtubule, acetylation, LRRK2, Roc-COR, domain, mutation, locomotor, deficits microtubule, acetylation, LRRK2, Roc-COR, domain, locomotor, deficits, mutation, repair microtubule, acetylation, LRRK2, Roc-COR, domain, locomotor, mutation, repair microtubule, acetylation, LRRK2, Roc-COR, domain, mutation, locomotor, deficits microtubule, acetylation, LRRK2, Roc-COR, domain, mutation, locomotor, deficits
70	Activation of PPM1D suppresses p53 function. PPM1D,p53,activation,suppression,cancer,proteins,molecularbiology,cellcycle,apoptosis PPM1D,p53,function,activation,inhibition,cancer,cell cycle,apoptosis PPM1D,p53,function,activation,inhibition,cancer,cell cycle,apoptosis PPM1D,p53,function,activation,inhibition,cancer,cell cycle,apoptosis PPM1D,p53,function,activation,inhibition,cancer,proteins,molecularbiology
72	Activator-inhibitor pairs are provided dorsally by Admpchordin. Activator-inhibitor, pairs, Admp, chordin, dorsal, signaling, embryonic development Activator-inhibitor, pairs, Admp, chordin, dorsal, developmental biology Activator-inhibitor, pairs, Admp, chordin, dorsal, signaling, molecular biology, developmental biology Activator-inhibitor, pairs, Admp, chordin, dorsal, development, signaling Activator-inhibitor, pairs, Admp, chordin, dorsal, signaling, embryonic development
859	Normal expression of RUNX1 has tumor-promoting effects. RUNX1,tumorpromotion,normalexpression,cancerbiology,molecularmechanisms RUNX1,tumor promotion,normal expression,cancer biology,molecular oncology RUNX1,tumor-promoting,effects,normal expression,cancer biology,molecular regulation RUNX1,tumor,promoting,expression,normally,effects,molecular biology,oncology,cancer research RUNX1,tumor-promoting,effects,normal expression,cancer biology,molecular regulation
619	Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments. vessel,density,fibrosis,chemotherapy,efficacy,treatment vessel density,fibrosis,chemotherapy,efficacy,treatment vessel,density,fibrosis,chemotherapy,efficacy,reduction,increase,treatment vessel,density,fibrosis,chemotherapy,efficacy,reduction,increased,treatment vessel,density,fibrosis,chemotherapy,efficacy,treatment
75	Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB. H.pylori, urease, polymeric, subunits, UreA, UreB H. pylori, urease, polymeric, subunits, UreA, UreB H. pylori, urease, polymeric, subunits, UreA, UreB H. pylori, urease, polymeric, subunits, UreA, UreB Active,H.pylori,urease,polymeric,subunits,UreA,UreB
1175	The PPR MDA5 has two N-terminal CARD domains. PPR, MDA5, N-terminal, CARD, domains PPR,MDA5,CARD,domains,N-terminal PPR, MDA5, N-terminal, CARD, domains PPR,MDA5,CARD,domains,N-terminal PPR, MDA5, N-terminal, CARD, domains
180	Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 leads to increased TDP-43-induced neuronal loss. TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking TDP-43, respiratory, complex, ND3, ND6, neuronal, loss, interaction, blocking
183	Bone marrow cells contribute to adult macrophage compartments. bone marrow, macrophages, adult, stem cells, hematopoiesis, monocytes, immune system Bone marrow, macrophages, adult, hematopoiesis, stem cells, immune system, monocytes, differentiation, myeloid lineage bone marrow, macrophages, adult stem cells, hematopoiesis, monocytes, tissue repair, immune response bone marrow, macrophages, adult stem cells, hematopoiesis, monocytes, immune system bone marrow, macrophages, adult stem cells, hematopoiesis, monocytes, tissue repair, immune response
1292	There is no association between HNF4A mutations and diabetes risks. HNF4A,mutations,diabetes,risk,association,genevariants HNF4A,mutations,diabetes,risk,association,genevariants HNF4A,mutations,diabetes,risk,association,genevariants HNF4A,mutations,diabetes,risk,association,genevariants HNF4A,mutations,diabetes,risk,association,genevariants
185	Breast cancer development is determined exclusively by genetic factors. breast cancer, development, genetic factors, exclusively, determinants breast cancer, development, genetic factors, heredity, genes, inheritance, oncology breast cancer, development, genetic factors, exclusivity, inheritance, oncology breast cancer, development, genetic factors, exclusively, determine breast cancer, development, genetic factors, exclusivity, inheritance
1290	There is an inverse relationship between hip fractures and statin use. hip fractures, statin use, inverse relationship hip fractures, statins, inverse relationship, bone health, cholesterol, medication, elderly, osteoporosis hip fractures, statin use, inverse relationship hip fractures, statins, inverse relationship, bone health, cholesterol medications, elderly, osteoporosis prevention, drug efficacy, epidemiology, medical research hip骨折,statin使用,逆向关系
1049	Ribosomopathies have a low degree of cell and tissue specific pathology. Ribosomopathies, cell-specific pathology, tissue-specific pathology, ribosome dysfunction, genetic disorders, hematopoietic disorders, bone marrow failure, developmental delay, anemia, leukopenia, thrombocytopenia Ribosomopathies, cell-specific pathology, tissue-specific pathology, ribosome dysfunction, genetic disorders, hematopoietic diseases, developmental disorders Ribosomopathies, cell specific, tissue specific, pathology, genetic disorders, ribosomal dysfunction, molecular pathology, cellular pathology, tissue pathology, ribosome biogenesis, protein synthesis, genetic mutations, disease mechanisms Ribosomopathies, cell specific, tissue specific, pathology, molecular biology, genetic disorders, ribosome function, disease mechanisms Ribosomopathies, cell specific pathology, tissue specific pathology, ribosome dysfunction
982	Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body. proteins,growthcone,ubiquitination,cellbody,synthesis Proteins,growthcone,ubiquitination,cellbody,synthesis proteins,growthcone,ubiquitination,cellbody,synthesis proteins,growth cone,ubiquitination,cell body,synthesis Proteins,growthcone,ubiquitination,cellbody,synthesis
742	Macrolides have no protective effect against myocardial infarction. macrolides, myocardial infarction, protective effect, cardiovascular disease, antibiotic resistance, clinical trial, heart attack, anti-inflammatory, mechanism of action macrolides, myocardial infarction, protection, clinical trial, efficacy, cardiovascular disease Macrolides, myocardial infarction, protective effect, clinical trial, antibiotic, cardiovascular, treatment Macrolides, myocardial infarction, protective effect, cardiovascular, antibiotics macrolides, myocardial infarction, protective effect, treatment, cardiovascular disease
501	Headaches are not correlated with cognitive impairment. headaches,cognitive,impairment,correlation,migraine,pain,research,study,symptoms headaches,cognitive,impairment,correlation,retrieval,query,study,research,evidence headaches,cognitive,impairment,correlation,retrieval,memory,neurology headaches,cognitive,impairment,correlation,retrieval,migraines,pain,symptoms,study,evidence headaches,cognitive,impairment,correlation,research,study,memory,functioning,pain,migraines,treatment,prevalence
743	Macrolides protect against myocardial infarction. Macrolides, myocardial infarction, antibiotics, cardiovascular, protection, mechanisms, clinical trials Macrolides, myocardial infarction, antibiotics, cardiovascular protection, drug effects Macrolides, myocardial infarction, antibiotics, cardiovascular protection, drug effects Macrolides, myocardial infarction, antibiotics, cardiovascular protection, drug efficacy Macrolides, myocardial infarction, antibiotics, cardiovascular, protection, mechanism, clinical trial, treatment, inflammation
985	Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy. Pseudogene, PTENP1, regulates, expression, PTEN, miRNA, decoy pseudogene, PTENP1, PTEN, miRNA, decoy, regulation, expression Pseudogene, PTENP1, PTEN, miRNA decoy, gene regulation pseudogene, PTENP1, PTEN, miRNA, decoy, regulation, expression Pseudogene, PTENP1, regulates, expression, PTEN, miRNA, decoy
502	Healthcare delivery efficiency in crowded delivery centers is impaired by improving structural, logistical, and interpersonal elements. Healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements healthcare, delivery, efficiency, crowded, centers, structural, logistical, interpersonal, elements
623	Individuals with low serum vitamin D concentrations have increased risk of multiple sclerosis. low, serum, vitamin, D, concentration, multiple, sclerosis, risk low, serum, vitamin, D, concentration, individuals, increased, risk, multiple, sclerosis low, serum, vitamin, D, concentration, increased, risk, multiple, sclerosis vitamin,D,serum,concentrations,multiple,sclerosis,risk,individuals low, serum, vitamin, D, concentration, individuals, increased, risk, multiple, sclerosis
744	Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein. Macropinocytosis,amino acids,protein,intracellular uptake,cell Macropinocytosis,amino acids,intracellular uptake,protein,cell supply macropinocytosis,amino acids,intracellular,uptake,protein,cell Macropinocytosis,amino acids,intracellular,uptake,protein,cell Macropinocytosis,amino acids,intracellular,uptake,protein,cellsupply
507	Helminths interfere with immune system control of macrophages activated by IL-4 favor Mycobacterium tuberculosis replication. helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, parasite, cytokine, host response, pathogeninteraction helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, immunology, parasite, microbiology helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, immunology, microbiology, parasite, inflammation Helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, replication helminths, immune system, macrophages, IL-4, Mycobacterium tuberculosis, infection, cytokines, immunity, pathogen interaction
628	Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of African origin. Infection,T-cell,lymphotropic,virus,African,origin,Human infection,T-cell,lymphotropic,virus,African,origin,human,HIV-1 Infection,African,origin,Human,T-cell,Lymphotropic,Virus,type,1 Infection,African,origin,human,T-cell,lymphotropic,virus,HTLV-1 infection, human, T-cell, lymphotropic, virus, type, 1, African, origin
508	Hematopoietic Stem Cell purification reaches purity rate of up to 50%. Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biotechnology, Isolation, Technique, Oncology, Hematology Hematopoietic, Stem, Cell, Purification, Purity, Rate Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biomedicine, Isolation, Technique, Biotechnology Hematopoietic, Stem, Cell, Purification, Purity, Rate, Biotechnology, Isolation, Technique Hematopoietic, Stem, Cell, Purification, Purity, Rate
1187	The YAP1 and TEAD complex tanslocates into the nucleus where it interacts with transcription factors and DNA-binding proteins that modulate target gene transcription. YAP1, TEAD, nucleus, transcription, factors, DNA-binding, proteins, target, gene, modulation YAP1, TEAD, nucleus, transcription, factors, DNA-binding, proteins, target, gene, transcription YAP1, TEAD, nuclear translocation, transcription factors, DNA-binding proteins, gene transcription YAP1, TEAD, nucleus, transcription, factors, DNA-binding, proteins, gene, modulation YAP1, TEAD, nuclear translocation, transcription factors, DNA-binding proteins, gene transcription
1185	The US health care system can save up to $750 million if 7% of patients waiting for kidney transplants participate in the optimized national kidney paired donation program. US, health care, savings, kidney transplants, optimization, national kidney paired donation program, patients, cost reduction US, health care, savings, kidney transplant, optimized program, national kidney paired donation, participation US, healthcare, system, savings, $750, million, patients, waiting, kidney, transplants, optimized, national, kidney, paired, donation, program US, health care, savings, kidney transplants, optimized, national kidney paired donation program, participation, cost reduction US, health care, savings, kidney transplants, optimized, national kidney paired donation program, participation, cost reduction
1062	S-nitrosylated GAPDH physiologically transnitrosylates histone deacetylases. S-nitrosylation,GAPDH,histone deacetylases,physiology,nitrosylation,molecular biology,proteins,enzymes,post-translationalmodification S-nitrosylation,GAPDH,histone deacetylases,physiological,nitrosylation,protein modification,molecular biology S-nitrosylation,GAPDH,transnitrosylation,histone deacetylases,physiology S-nitrosylation,GAPDH,physiology,transnitrosylation,histone deacetylases,histones,nitric oxide,DNA regulation S-nitrosylation,GAPDH,physiology,transnitrosylation,histone deacetylases,histones,nitric oxide
1180	The PRR MDA5 is a sensor of RNA virus infection. PRR, MDA5, RNA, virus, infection, sensor PRR, MDA5, RNA, virus, infection, sensor PRR, MDA5, RNA, virus, infection, sensor PRR, MDA5, RNA, virus, infection, sensor PRR, MDA5, RNA, virus, infection, innate, immunity, sensor
198	CCL19 is absent within dLNs. CCL19, dLNs, lymph nodes, immune response, chemokine, immunology CCL19, dLNs, lymph nodes, immune response, chemokine, antigen presentation CCL19, dLNs, dendritic, lymph nodes, absence, chemokine CCL19, dLNs, dendritic, lymph nodes, absence, chemokine CCL19, dLNs, dendritic, lymph nodes, absence, chemokine, immune response
870	Obesity decreases life quality. obesity, life quality, health, mortality, obesity-related, well-being, overweight, fitness obesity, life, quality, health, impact, weight, mortality, nutrition, exercise, overweight obesity, life quality, health, BMI, weight, mortality, wellbeing, obesity-related, lifespan obesity, life, quality, health, impact, overweight, mortality, fitness, nutrition, metabolic obesity, life quality, health, weight, mortality, well-being, obesity rate, fatness, overweight, fitness
993	Pyridostatin destabilizes the G - quadruplex in the telomeric region. Pyridostatin,G-quadruplex,telomeric region,DNA structure,stabilization,biomoleculeinteraction,molecular biology,radioprotector Pyridostatin,G-quadruplex,telomeric region,DNA,stability,structure,molecular biology,Therapeutics Pyridostatin,G-quadruplex,telomeric,region,stabilization,dna,biochemistry,molecularbiology,Therapeutics Pyridostatin,telomeric,G-quadruplex,stabilization,drug,biophysics,molecular biology,RNA,DNA,telomere Pyridostatin,G-quadruplex,telomeric,region,molecular,biology,DNA,stabilization,therapy,cancer,research
873	Obesity is determined solely by environmental factors. obesity, environmental factors, genetics, lifestyle, diet, exercise, metabolism, socioeconomics, psychology obesity, environmental factors, genetics, lifestyle, diet, metabolism obesity, environmental factors, genetics, lifestyle, diet, metabolism, socioeconomic status, physical activity obesity, environmental, factors, genetics, lifestyle, diet, metabolism obesity, environmental, factors, genetics, lifestyle, metabolism, diet, exercise, socioeconomics, nutrition
1179	The PRR MDA5 has a central DExD/H RNA helices domain. PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain PRR, MDA5, DExD/H, RNA, domain
1298	Thigh-length graduated compression stockings (GCS) did not reduce deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke. thigh-length,gcs,deep,vein,thrombosis,hospital,immobile,acute,stroke,reduction,keywords,retrieval thigh-length, graduated, compression, stockings, GCS, deep, vein, thrombosis, hospital, immobile, acute, stroke thigh-length, graduated, compression, stockings, GCS, deep, vein, thrombosis, patients, hospital, immobile, acute, stroke thigh-length, graduated, compression, stockings, GCS, deep, vein, thrombosis, patients, hospitalized, immobile, acute, stroke thigh-length, graduated, compression, stockings, deep, vein, thrombosis, patients, immobile, acute, stroke, hospital
513	High cardiopulmonary fitness causes increased mortality rate. cardiopulmonary, fitness, mortality, rate, correlation, exercise, health, lifespan, cardiovascular, pulmonary cardiopulmonary, fitness, mortality, rate, correlation, cardiovascular, pulmonary, endurance, health, exercise, risk, mortality率, 健康, 运动, 风险 cardiopulmonary, fitness, mortality, rate, high, correlation, exercise, health, cardiovascular, pulmonary cardiopulmonary, fitness, mortality, rate, high, exercise, endurance, cardiovascular, pulmonary, health cardiopulmonary, fitness, mortality, rate, high, exercise, health, cardiovascular, pulmonary, lifespan, endurance, mortality risk, physical activity
514	High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter. dietary calcium, hyperparathyroidism, 25(OH)D, vitamin D, secondary hyperparathyroidism, prevention, bone health, renal disease, nutrition, supplementation calcium, intake, prevention, secondary, hyperparathyroidism, 25(OH)D, levels, vitamin D, nutrition, supplementation dietary calcium, secondary hyperparathyroidism, 25(OH)D, vitamin D, nephrology, bone health, supplementation dietary calcium, hyperparathyroidism, 25(OH)D, vitamin D, bone health, kidney disease, supplementation calcium, diet, hyperparathyroidism, vitamin D, 25(OH)D, supplementation, prevention
756	Many proteins in human cells can be post-translationally modified at lysine residues via acetylation. proteins, human cells, post-translational modification, lysine residues, acetylation proteins, human cells, post-translational modification, lysine, acetylation proteins, human cells, post-translational modification, lysine residues, acetylation proteins, human cells, post-translational modification, lysine, acetylation proteins, human cells, post-translational modification, lysine, acetylation
636	Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate. PTEN,inositol,lipid,phosphatase,Ptdlns(3,4)P,2,phosphatidylinositol,4-phosphate,retrieval PTEN,inositol,lipid,phosphatase,Ptdlns(3,4)P,2,phosphatidylinositol,4-phosphate PTEN,inositol,lipid,3-phosphatase,Ptdlns(3,4)P2,phosphatidylinositol,4-phosphate PTEN,inositol,lipid,phosphatase,Ptdlns(3,4)P2,phosphatidylinositol,4-phosphate PTEN,inositol,lipid,phosphatase,Ptdlns(3,4)P2,phosphatidylinositol,4-phosphate
516	High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD). CRP, COPD, exacerbations, risk, inflammation CRP, COPD, exacerbations, inflammation, biomarker CRP, COPD, exacerbations, risk, inflammation CRP, COPD, exacerbations, risk, inflammation CRP, COPD, exacerbations, inflammation, risk, biomarker
637	Input from  mental and physical health care professionals is effective at decreasing homelessness. mental-health, physical-health, healthcare-professionals, homelessness, input, effectiveness mentalhealth, physicalhealth, healthcareprofessionals, homelessness, inputeffectiveness mental health, physical health, healthcare professionals, homelessness, input, effectiveness mental health, physical health, healthcare professionals, homelessness, input, effectiveness input,mental,physical,healthcare,professionals,effective,decreasing,homelessness
879	Occupancy of ribosomes by IncRNAs do not make functional peptides. ribosomes, IncRNAs, occupancy, functional, peptides ribosomes, IncRNAs, functional peptides, occupancy ribosomes, IncRNAs, occupancy, functional, peptides ribosomes, IncRNAs, occupancy, functional, peptides ribosomes, IncRNAs, occupancy, functional, peptides
517	High levels of copeptin decrease risk of diabetes. copeptin, diabetes, risk, high, levels copeptin, diabetes, risk, high, levels copeptin, diabetes, risk, high, levels copeptin, diabetes, risk, high, levels copeptin, diabetes, risk, high, levels
759	Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have a dramatic impact in reducing malaria transmission. mathematical models, artemisinin-based combination therapy, nongametocytocidal drugs, malaria transmission, impact mathematical models, artemisinin-based combination therapy, nongametocytocidal drugs, malaria transmission, reduction, impact mathematical models, artemisinin-based combination therapy, nongametocytocidal drugs, malaria transmission, reduction, impact Mathematical models, Artemisinin-based combination therapy, nongametocytocidal drugs, malaria transmission, reduction, impact mathematical models, artemisinin-based combination therapy, nongametocytocidal drugs, malaria transmission, reduction, impact
94	Albendazole is used to treat lymphatic filariasis. albendazole, lymphatic, filariasis, treatment, drug, parasitic, infection, medication albendazole, lymphatic, filariasis, treatment, medication albendazole, lymphatic, filariasis, treatment albendazole, lymphatic, filariasis, treatment, drug albendazole, lymphatic, filariasis, treatment, drug, parasitic, infection
99	Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding. Alizarin, hydrogen bonds, PGAM1, substrate binding, residues Alizarin,Hydrogen bonds,PGAM1,Substrate binding,residues Alizarin,Hydrogen bonds,PGAM1,Substrate binding,Residues Alizarin, hydrogen bonds, PGAM1, substrate binding, residues Alizarin, hydrogen bonds, PGAM1, substrate binding, residues
1197	The availability of safe places to study is not effective at decreasing homelessness. safe places, study locations, homelessness, effectiveness, housing, accessibility, education, urban areas, poverty, resources, policy, infrastructure safe places, study, effectiveness, homelessness, housing, availability, locations, education, impact safe places, study locations, homelessness, effectiveness, availability, housing, education access, poverty, urban areas, youth homelessness, college students, community resources, public spaces safe study spaces, homelessness, effectiveness, shelter availability, education environment, housing solutions, urban planning, social policies, community resources safe places, study locations, homelessness, effectiveness, housing, education, resources, urban areas, socioeconomics, policy, interventions
1196	The availability of safe places to study is effective at decreasing homelessness. study spaces, safety, homelessness, accessibility, shelters, educationimpact, housing, resources, urbanareas, poverty safe study spaces, homelessness prevention, educational accessibility, housing stability, community resources, academic environment safety safe study spaces, homelessness prevention, education accessibility, housing stability, community resources, academic environments, shelter alternatives, learning spaces, poverty reduction, urban planning, social services safe study spaces, homelessness prevention, educational accessibility, housing stability, community resources, student well-being, urban planning, public spaces, affordable housing, social impact safe places, study areas, homelessness, housing, education, shelter, resources, accessibility, youth, community, policies
1194	The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'. TatAd, complexes, arm density, structural rearrangements, Class1, charge zipper mechanism TatAd, complexes, arm, density, structural, rearrangements, Class1, charge, zipper, mechanism TatAd, complexes, arm density, structural rearrangements, Class1, charge zipper mechanism TatAd, complexes, arm, density, structural, rearrangements, charge, zipper, mechanism, Class1 TatAd, complexes, arm density, structural rearrangements, Class1, charge zipper mechanism
1191	The amount of publicly available DNA data doubles every 10 years. DNA, data, doubling, timeframe, public, genomics, biotechnology DNA, data, doubling, trend, public, genetics DNA, data, doubling, trend, genetic, information, bioinformatics, storage, growth DNA, data, doubling, trend, public, genetics, bioinformatics DNA, data, doubling, public, decade, genomics
880	Occupancy of ribosomes by IncRNAs mirror 5 0-UTRs ribosomes, IncRNAs, 5',UTRs, occupancy, molecular biology, RNA, regulation, translation ribosomes, IncRNAs, 5'UTRs, occupancy, mirror, RNA, translation, genetics ribosomes, IncRNAs, 5,UTRs, occupancy, mirror, RNA, translation ribosomes, IncRNAs, 5'UTRs, occupancy, mirror, RNA, translation, regulation ribosomes, IncRNAs, occupancy, 5_utrs, RNA, mirroring, molecular biology, genetics
882	Omnivores produce less trimethylamine N-oxide from dietary I-carnitine than vegetarians. omnivores, trimethylamine, N-oxide, dietary, I-carnitine, vegetarians dietary I-carnitine, trimethylamine N-oxide, omnivores, vegetarians, gut microbiota Omnivores, trimethylamine, N-oxide, dietary, I-carnitine, vegetarians Omnivores, trimethylamine, N-oxide, dietary, I-carnitine, vegetarians dietary I-carnitine, trimethylamine N-oxide, omnivores, vegetarians, gut microbiota
641	Insomnia can be effectively treated with cognitive behavioral therapy. insomnia,cognitive,behavioral,therapy,effective,treatment,sleep,disorder,psychology,health,mind,body insomnia,cognitive,behavioral,therapy,treatment,sleep,disorder,psychology,health,mind,body insomnia,cognitive,behavioral,therapy,treatment,sleep,disorder,mind,body,habits,management,psychology,health,symptoms,cures,therapy/session,session/therapy insomnia,cognitive,behavioral,therapy,effective,treatment,sleep,disorders,mental,health insomnia,cognitive,behavioral,therapy,treatment,sleep,disorder,mind,body,intervention,management
521	High-sensitivity cardiac troponin T (HSCT-T) dosage may not be diagnostic if the onset of symptoms occurs less than 3 hours before acute myocardial injury (AMI). High-sensitivity, cardiac,troponin,T,dosage,symptoms,acute,myocardial,injury,AMI,time-onset High-sensitivity, cardiac,troponin,T,HSCT-T,dosage,diagnostic,symptoms,onset,acute,myocardial,injury,AMI,time,window High-sensitivity, cardiac,troponin,T,HSCT-T,dosage,symptoms,onset,acute,myocardial,injury,AMI,timefenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfenfen High-sensitivity, cardiac,troponin,T,HSCT-T,dosage,symptoms,acute,myocardial,injury,AMI,onset,timeeliness,diagnostic,test,measurement,evaluation HSCT-T,dosage,diagnostic,onset,symptoms,acute,myocardial,injury,AMI,time窗限3小时
644	Insulin increases risk of severe kidney failure. insulin,kidney,failure,risk,severe insulin,kidney,failure,risk,severe insulin,kidney failure,risk,failure,severe,diabetes,end-stagerenal disease,glycemic control,diabetic nephropathy,hypoglycemia insulin,kidney,failure,risk,endocrine,diabetes,glycemic,renal,comorbidity,hormone insulin,kidney,failure,risk,endocrine,diabetes,renal,health,potential,complication
887	Only a minority of cells survive development after differentiation into stress-resistant spores. minority,cells,survive,development,differentiation,stress-resistant,spores minority,cells,survive,development,differentiation,stress-resistant,spores survival, cells, minority, development, differentiation, stress-resistant, spores minority,cells,survive,differentiation,stress-resistant,spores minority,cells,survive,differentiation,stress-resistant,spores
525	Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors. Histone, demethylase, recruitment, transient, decrease, histone, methylation, ligand, dependent, induction, transcription, nuclear, receptors Histone, demethylase, recruitment, transient, decrease, histone, methylation, ligand, dependent, induction, transcription, nuclear, receptors Histone,demethylase,recruitment,methylation,nuclear,receptors,transcription,ligand-dependent,induction,temporary Histone, demethylase, recruitment, transient, methylation, ligand, dependent, induction, transcription, nuclear, receptors Histone,demethylase,recruitment,methylation,nuclear,receptors,transcription,ligand-dependent,induction,temporary
768	Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT). Mercaptopurine,methylmercaptopurine,thiopurine,methyltrasnferase,tpmt,anabolization Mercaptopurine,methylmercaptopurine,thiopurine,methyltrasnferase,TPMT,anabolism Mercaptopurine,methylmercaptopurine,thiopurine,methyltrasnferase,TPMT,anabolized,inactive Mercaptopurine,methylmercaptopurine,thiopurine methyltrasnferase,TPMT,isobutyl mercaptopurine Mercaptopurine, anabolized, methylmercaptopurine, thiopurine, methyltransferase, TPMT
527	Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress. Homozygous deletion, murine Sbds gene, osterix, mesenchymal stem cells, progenitor cells, MPCs, oxidative stress Homozygous deletion,murine,Sbds gene,ostérix,mesenchymal stem cells,progenitor cells,MPCs,oxidative stress Homozygous, deletion, murine, Sbds, gene, osterix, expressing, mesenchymal, stem, progenitor, cells, MPCs, prevents, oxidative, stress Homozygous, deletion, murine, Sbds, gene, osterix, expressing, mesenchymal, stem, progenitor, cells, MPCs, prevents, oxidative, stress Homozygous deletion, murine, Sbds gene, osterix, mesenchymal stem, progenitor cells, MPCs, oxidative stress
528	Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) patients produce Immunoglobulin G (IgG) antibodies which cross-react with an immunodominant epitope in Tax. Human,T-lymphotropic,virus,Type-I,associated,myelopathy,tropical,spastic,paraparesis,HAM/TSP,Immunoglobulin,G,IgG,antibodies,epitope,Tax Human,T-lymphotropic,virus,Type-I,associated,myelopathy,tropical,spastic,paraparesis,HAM/TSP,Immunoglobulin,G,IgG,antibodies,immunodominant,epitope,Tax Human T-lymphotropic virus, type-I, HAM/TSP, myelopathy, tropical spastic paraparesis, Immunoglobulin G, IgG, antibodies, Tax, epitope Human_T-lymphotropic_virus_I, HAM/TSP, Immunoglobulin_G, IgG, antibodies, Tax_protein, immunodominant_epitope Human T-lymphotropic virus, type-I, HAM/TSP, patients, Immunoglobulin G, antibodies, cross-react, Tax, immunodominant epitope
649	Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance classroom learning, web-based learning, collaborative learning, performance, integration, technology, education, online collaboration, blended learning classroom learning, web-based learning, collaborative learning, class performance, integration, effectiveness, technology, education, online collaboration, face-to-face collaboration, hybrid learning classroom, collaborative, learning, web-based, integration, performance, subpar, effectiveness, technology, education, pedagogy classroom learning, web-based learning, collaborative learning, performance, integration, education, technology, students, effectiveness classroom, collaborative, learning, web-based, performance, integration, effectiveness, technology, education, interaction
1088	Silencing of Bcl2 is important for the maintenance and progression of tumors. Bcl2,silencing,tumors,maintenance,progression,cancer,bcl2 gene Bcl2,silencing,tumors,maintenance,progression,oncology,molecular biology,cancer therapy,gene regulation,microRNAs,RNA interference Bcl2,silencing,tumors,maintenance,progression,cancer,bcl2 gene Bcl2,silencing,tumors,maintenance,progression,cancertherapy,oncology,molecularbiology,geneexpression,Mitosis Bcl2,silencing,tumors,maintenance,progression,oncology,gene expression,molecular biology,cancer therapy,apoptosis regulation
1086	Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants. sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction Sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction Sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction sildenafil, erectile, function, SSRI, antidepressants, sexual, dysfunction
770	Metastatic colorectal cancer treated with a single agent fluoropyrimidines resulted in reduced efficacy and lower quality of life when compared with oxaliplatin-based chemotherapy in elderly patients. metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,efficacy,quality,life Metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,chemotherapy,elderly,efficacy,quality,life Metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,quality,life,efficacy metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,chemotherapy,elderly,efficacy,quality,life metastatic,colorectal,cancer,fluoropyrimidines,oxaliplatin,elderly,efficacy,quality,life
410	Febrile seizures increase the threshold for development of epilepsy. febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase febrile seizures, epilepsy, threshold, development, increase
411	Febrile seizures reduce the threshold for development of epilepsy. febrile seizures, epilepsy, neuronal excitability, threshold, brain, fever, children, neurology febrile seizures, epilepsy, seizure threshold, neurological disorders, child health, pediatric seizures febrile seizures, epilepsy, seizure threshold, brain, children, fever, neurological, risk factor, pediatric, convulsion febrile seizures, epilepsy, seizure threshold, neurology, pediatric seizures, brain function, neurological disorders febrile seizures, epilepsy, neuronal excitability, brain, childhood, seizure threshold, neurology, genetics, risk factors
532	Hyperfibrinogenemia decreases rates of femoropopliteal bypass thrombosis. Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,fibrinogen Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,improvement,retention,fibrinogen Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,fibrinogen,vascular,surgery,angioplasty Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,improvement,rates,fibrinogen Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,retention,rates,fibrinogen
533	Hyperfibrinogenemia increases rates of femoropopliteal bypass thrombosis. Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,increase,fibrinogen Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,increase Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates,increase Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,vascular,surgery,clotting,disease,risk,factors Hyperfibrinogenemia,femoropopliteal,bypass,thrombosis,rates
775	Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) reveal increased sensitivity to ionizing radiation (IR). mice,DNA,polymerase I,defective,sensitivity,ionizing radiation mice,DNA,polymerase I,defective,sensitivity/ionizing radiation Mice,DNA,polymerase I,defective,sensitivity,ionizing radiation,IR genotoxicity mice,DNA,polymerase,defective,ionizing,radiation,sensitivity mice,DNA,polymerase I,polI,sensitivity/ionizing radiation,IR
1199	The benefits of colchicine were achieved with effective widespread use of secondary prevention strategies such as high-dose statins. colchicine, benefits, secondary, prevention, strategies, high-dose, statins colchicine, benefits, secondary prevention, high-dose, statins colchicine,benefits,secondary prevention,strategies,high-dose statins,widespread use colchicine,benefits,secondary prevention,strategies,high-dose statins,widespread use colchicine,benefits,secondary prevention,strategies,high-dose statins,widespread use
535	Hypertension is frequently observed in type 1 diabetes patients. Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed Hypertension,type,1,diabetes,patients,frequently,observed
415	Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia. Apolipoprotein E4,APOE4,female,dementia,risk,carrier,genetics,alzheimer,amyloid-beta Apolipoprotein,E4,carrier,dementia,risk,female Apolipoprotein,E4,allele,female,dementia,risk,genetics,molecular,biochemistry Apolipoprotein,E4,APOE4,female,dementia,risk,carrier,genetics,alzheimer's Apolipoprotein,E4,carrier,female,dementia,risk faktor,genetic,predisposition
536	Hypocretin neurones induce panicprone state in rats. Hypocretin, Neurones, Panic, Rats, Induce, State Hypocretin, Neurones, Panic, Rats, Induce, State, Anxiety Hypocretin, neurones, panicprone, rats, neuroscience, behavior, anxiety, sleep, hypocretinoma, orexin Hypocretin, neurones, panic, rats, neurobiology, stress, anxiety, neurotransmitter Hypocretin, Neurones, Panic, Rats, Induce, Neurotransmitter, Anxiety, Behavior, Neuroscience, Sleep, Disorders
659	Ivermectin is used to treat lymphatic filariasis. Ivermectin, lymphatic filariasis, treatment, medication, parasites Ivermectin, lymphatic filariasis, treatment, medication, parasite, infection Ivermectin, lymphatic, filariasis, treatment, medicine, drug Ivermectin, lymphatic, filariasis, treatment Ivermectin, lymphatic filariasis, treatment
539	Hypoglycemia increases the risk of dementia. hypoglycemia,dementia,risk,factors,glucose,brain,function,age,diabetes hypoglycemia,dementia,risk,factor,glucose,brain,health,prediabetes,diabetes,age,study,research hypoglycemia,dementia,risk,factors,glucose,blood,sugar,age,diabetes,neurodegeneration,mortality hypoglycemia,dementia,risk,factors,glucose,blood,sugar,memory,impairment,diabetes,elderly,population,studies,research hypoglycemia,dementia,risk,factors,study,evidence,diabetes,hormones,blood glucose,neurodegeneration
1099	Statins decrease blood cholesterol. statins, cholesterol, blood, lipid, medication, reduction, heart, health statins, cholesterol, blood, medication, treatment, lowering, lipid, heart, disease, drugs statins, cholesterol, blood, level, medication, treatment statins, cholesterol, blood, medication, lipid, reduction, heart, health statins, cholesterol, blood, medication, lowering, cardiovascular, health
660	Ivermectin is used to treat onchocerciasis. Ivermectin,onchocerciasis,treatment,medicine,filaricide,eye,disease,skin Ivermectin,onchocerciasis,treatment,medication,parasite,filaria,disease,drug,medicine Ivermectin,onchocerciasis,treatment,drug,medication,Welchèn Ivermectin,onchocerciasis,treatment,drug,parasite,medicine Ivermectin,onchocerciasis,treatment,drug,medication,filarial,disease,WoNelson
781	Mice that lack Interferon-γ or its receptor exhibit high resistance to experimental autoimmune myocarditis. Mice, Interferon-γ, receptor, experimental autoimmune myocarditis, resistance Mice, Interferon-γ, receptor, experimental, autoimmune, myocarditis, resistance Mice, Interferon-γ, receptor, experimental, autoimmune, myocarditis, resistance Mice, Interferon-γ, receptor, experimental, autoimmune, myocarditis, resistance Mice, Interferon-γ, receptor, experimental, autoimmune, myocarditis, resistance
540	Hypothalamic glutamate neurotransmission is crucial to energy balance. Hypothalamus, glutamate, neurotransmission, energy, balance Hypothalamus, glutamate, neurotransmission, energy, balance Hypothalamus, glutamate, neurotransmission, energy, balance hypothalamus, glutamate, neurotransmission, energy, balance Hypothalamus, glutamate, neurotransmission, energy, balance
783	Mice without IFN-γ or its receptor are resistant to EAM induced with α-MyHC/CFA. Mice, IFN-γ, receptor, EAM, α-MyHC, CFA, resistance Mice, IFN-γ, receptor, EAM, α-MyHC, CFA, resistance Mice,IFN-γ,receptor,EAM,α-MyHC,CFA,resistance Mice, IFN-γ, receptor, EAM, α-MyHC/CFA, resistance Mice, IFN-γ, receptor, EAM, α-MyHC, CFA, resistance
300	Cytosolic proteins bind to iron-responsive elements on mRNAs coding for DMT1. Cytosolic proteins bind to iron-responsive elements on mRNAs coding for proteins involved in iron uptake. Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake, binding Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake Cytosolic, proteins, iron, responsive, elements, mRNAs, DMT1, iron, uptake
421	Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules. flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules,diffusion,interactions flexible,molecules,steric,hindrance,rigid,molecules,tumor,microenvironment,microenviroment flexible,molecules,steric,hindrance,rigid,molecules,tumor,microenvironment,microenviroment flexible,molecules,steric,hindrance,tumor,microenvironment,rigid,molecules,diffusion,size,shape
784	MicroRNA is involved in the regulation of Neural Stem Cell (NSC) differentiation and proliferation dynamic homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis MicroRNA, Neural Stem Cell, differentiation, proliferation, homeostasis
785	Microarray results from culture-amplified mixtures of serotypes correlate poorly with microarray results from uncultured mixtures. microarray, culture-amplified, serotypes, correlation, uncultured, mixtures microarray,culture,serotypes,uncultured,mixtures,correlation microarray, serotypes, culture, uncultured, correlation, mixtures microarray, culture-amplified, serotypes, uncultured, correlation microarray, culture-amplified, serotypes, correlation, uncultured, mixtures
544	IFIT1 restricts viral replication by sequestrating mis-capped viral RNAs. IFIT1,viral replication,mis-capped,RNA,sequestration IFIT1,viral replication,mis-capped,RNAs,sequestration,virus/host interaction IFIT1,viral replication,mis-capped,viral RNAs,sequestration IFIT1,viral replication,mis-capped viral RNAs,sequestration,virus:host interaction IFIT1,viral replication,mis-capped,viral RNAs,sequestration
303	DMRT1 is a sex-determining gene that is epigenetically regulated by the MHM region. DMRT1, sex determination, epigenetics, MHM region DMRT1, sex determination, epigenetics, MHM region DMRT1, sex-determination, epigenetics, MHM, gene regulation DMRT1, sex determination, epigenetics, MHM region, gene regulation DMRT1, sex determination, epigenetic regulation, MHM region
1089	Smc5/6 engagment drives the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding. SMC5/6, SUMOylation, Mms21, ATP-dependent, remolding, E3 ligase Smc5/6, SUMO, E3 ligase, Mms21, ATP, remodeling, DNA repair Smc5/6, SUMOylation, Mms21, ATP, E3 ligase, chromatin, remodeling, cell cycle, DNA repair Smc5/6, SUMO, E3 ligase, Mms21, ATP, remodeling Smc5/6, SUMOylation, Mms21, ATP-dependent, remolding, E3 ligase
549	IRG1 has antiviral effects against neurotropic viruses. IRG1, antiviral, neurotropic, viruses, immune response, protein, protection, infection IRG1, antiviral, neurotropic, viruses, immune response, interferon, protein, gene expression, viral infection, neuronal cells, pathogendefense, virology, biochemistry, molecular biology IRG1, antiviral, neurotropic, viruses, immune, response, mechanism, protein, infection, protection IRG1, antiviral, neurotropic, viruses, immune, response, mechanism, infection, protection IRG1, antiviral, neurotropic, viruses, immunity, gene, protein, interferon, response
551	ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR). ITAM,phosphorylation,T cell receptor,TCR,echo-domain,cytoplasmic tail,signal transduction ITAM, phosphorylation, TCR, signal, echo-domain, cytoplasmic tail, immune receptor tyrosine-based activation motif ITAM,phosphorylation,TCR,T cell receptor,echo-domain,cytoplasmic tail,signal transduction ITAM, phosphorylation, TCR, echo-domain, cytoplasmic, signal, transfer, immunology ITAM, phosphorylation, TCR, echo-domain, cytoplasmic tail, signal transduction
793	Mitochondria are uninvolved in apoptosis. mitochondria, apoptosis, involvement, cell death, organelle mitochondria, apoptosis, involvement, cell death, mitochondria function mitochondria, apoptosis, involvement, cell death, organelle mitochondria, apoptosis, uninvolved, cellular biology, death, organelle mitochondria, apoptosis, involvement, cell death, organelle
431	FoxO3a activation in neuronal death is mediated by reactive oxygen species (ROS). FoxO3a, neuronal death, reactive oxygen species, ROS, activation, mediation FoxO3a, neuronal death, reactive oxygen species, ROS, activation FoxO3a, neuronal death, reactive oxygen species, ROS, activation FoxO3a, neuronal death, reactive oxygen species, ROS, activation, mediation FoxO3a, neuronal death, reactive oxygen species, ROS, activation
552	IgA plasma cells that are specific for transglutaminase 2 accumulate in the duodenal mucosa on commencement of a gluten-free diet. IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet, accumulation IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet IgA plasma cells, transglutaminase 2, duodenal mucosa, gluten-free diet, accumulation
674	LDL cholesterol has no involvement in the development of cardiovascular disease. LDL, cholesterol, cardiovascular, disease, involvement, mechanism LDL, cholesterol, cardiovascular, disease, involvement, metabolic, genetics, diet, inflammation LDL, cholesterol, cardiovascular, disease, involvement, metabolism LDL, cholesterol, cardiovascular, disease, involvement, metabolism, atherosclerosis, genetics, lifestyle, diet LDL, cholesterol, cardiovascular, disease, involvement, metabolic, genetics, inflammation, atherosclerosis, risk_factors
312	De novo assembly of sequence data has more specific contigs than unassembled sequence data. de novo, assembly, contigs, unassembled, sequence, data, specificity de novo assembly, contigs, unassembled sequence data, bioinformatics, genome assembly, sequencing technology, genetic analysis de novo assembly, contigs, unassembled sequence data, genome assembly, bioinformatics, sequencing, genetic analysis de novo assembly, contigs, unassembled sequence data, genome assembly, bioinformatics, sequencing technology de novo, assembly, contigs, sequencing, data, specificity
554	Immune complex triggered cell death leads to extracellular release of neutrophil protein HMGB1. immune complexes, cell death, extracellular release, neutrophils, HMGB1, cytokines, inflammation immune complexes, cell death, extracellular release, neutrophil, HMGB1, inflammatory response immune complexes, cell death, extracellular release, neutrophil, HMGB1, inflammation immune complexes, cell death, extracellular, neutrophil, protein, HMGB1 immune complexes, cell death, extracellular, neutrophils, HMGB1, protein
314	Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome. deamination, cytidine, uridine, minus strand, viral DNA, G-to-A, mutations, genome deamination,cytidine,uridine,viral DNA,minus strand,G-to-A mutations,catastrophic deamination, cytidine, uridine, minus strand, viral DNA, G-to-A, mutations, genome deamination,cytidine,uridine,viral DNA,minus strand,G-to-A mutations,catastrophic deamination,cytidine,uridine,viral DNA,minus strand,G-to-A mutations,catastrophic
436	Free histones are degraded by a Rad53-dependent mechanism once DNA has been replicated. Free histones, Rad53, DNA replication, degradation, mechanism Free histones, Rad53, DNA replication, degradation, mechanism free histones, Rad53, DNA replication, degradation, mechanism free histones, Rad53, DNA replication, degradation, mechanism free histones, Rad53, DNA replication, degradation, mechanism
437	Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model. genomic alterations, functional consequences, Myelodysplastic syndrome, animal model, understanding, molecular mechanisms, hematopoiesis, cancer biology, genetic variation, blood disorders functional consequences, genomic alterations, Myelodysplastic syndrome, MDS, animal model, understanding, biological impacts, hematopoietic dysfunction genomic alterations, functional consequences, Myelodysplastic syndrome, animal model, understanding genomic alterations, functional consequences, Myelodysplastic syndrome, animal model, understanding genomic alterations, functional consequences, Myelodysplastic syndrome, animal model, understanding, hematopoietic disorders
439	Fz/PCP-dependent Pk localizes to the anterior membrane of neuroectoderm cells during zebrafish neuralation Fz/PCP, PK, zebrafish, neuroectoderm, neuralation, anterior membrane, localization Fz/PCP, PK, zebrafish, neuralation, neuroectoderm, anterior membrane Fz/PCP, Pk, anterior membrane, neuroectoderm, zebrafish, neuralation Fz/PCP, PK, neuroectoderm, zebrafish, neuralation, anterior membrane Fz/PCP, PK, neuroectoderm, zebrafish, neuralation, anterior membrane
560	Immune responses result in the development of inflammatory Th17 cells and anti-inflammatory iTregs. immune responses,Th17 cells,iTregs,inflammation,regulatory T cells Immune responses,Th17 cells,iTregs,inflammation,anti-inflammatory,development immune responses, Th17 cells, anti-inflammatory, iTregs, cytokines, inflammation, immune regulation, T-helper cells immune responses, Th17 cells, anti-inflammatory, iTregs, cytokines, T-helper cells, inflammation immune responses, Th17 cells, iTregs, inflammation, regulatory T cells
440	Fz/PCP-dependent Pk localizes to the anterior membrane of notochord cells during zebrafish neuralation. Fz/PCP, Pk, zebrafish, neuralation, notochord, anterior membrane Fz/PCP, Pk protein, notochord, zebrafish, neuralation, anterior membrane Fz/PCP, Pk, notochord, zebrafish, neuralation, anterior membrane Fz/PCP, PK, zebrafish, neuralation, notochord, localization, anterior membrane Fz/PCP, PK, notochord, zebrafish, neuralation, localization, anterior membrane
1303	Tirasemtiv has no effect on fast-twitch muscle. tirasemtiv, fast-twitch, muscle, efficacy, clinical trial, neurology, treatment, therapy, myopathy, dystrophy, biomedical, research tirasemtiv, fast-twitch, muscle, efficacy, clinical trial, neuromuscular, disease, treatment, research, pharmacology tirasemtiv,muscle type,fast-twitch,effect,research,studies,clinical tirasemtiv, fast-twitch, muscle, effect, clinical, trial, neurology, ALS tirasemtiv, fast-twitch, muscle, efficacy, clinical, study, neurology, ALS
684	Lack of clpC does not affect sporulation efficiency in Bacillus subtilis cells. Lack,clpC,Bacillus subtilis,sporulation,efficiency Lack,clpC,sporulation,Bacillus subtilis,cells,effect,efficient Lack,clpC,sporulation,Bacillus subtilis,cells,effect Lack,clpC,sporulation,Bacillus subtilis,effect,cells clpC, Bacillus subtilis, sporulation, efficiency, gene deletion
443	GATA-3 is important for hematopoietic stem cell (HSC) function. GATA-3,hematopoietic stem cell,function,regulation,molecular biology,immune system GATA-3,hematopoietic.stem.cell,function,regulation,molecular.biology,transcription.factor,immune.system GATA-3,hematopoietic.stem.cell,function,molecular.biology,transcription.factor,DNA.bindings,immunology,stem.cell.research,cell.differentiation,regulation.of.expressions GATA-3,hematopoietic stem cell,function,stem cells,immune system,gene expression,molecular biology,regulation,development,cell differentiation,t-cell development GATA-3,HSC,function,hematopoietic.stem.cell,molecular.gene.regulation,immunology,developmental.biology
324	Deleting Raptor reduces G-CSF levels. Deleting,Raptor,G-CSF,levels,therapy,myeloid,disease,cytokine Deleting,Raptor,G-CSF,levels,bone marrow,myeloid differentiation,myelosuppression,therapy,clinical trial,biological response modifiers,hematopoietic growth factors,immunotherapy Deleting,Raptor,G-CSF,levels,therapy,clinical,biochemistry,hematology,treatment Deleting,Raptor,G-CSF,levels,bone marrow,neutrophils,cytokines,hematopoiesis,pharmacology Deleting,Raptor,G-CSF,levels,bone marrow,neutropenia,mortality,therapy,clinical trials,hematopoiesis
327	Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype. Deletion, αvβ8, spontaneous, inflammatory, phenotype αvβ8 integrin,inflammation,spontaneous phenotype,genetic deletion,retrieval keywords Deletion, αvβ8, inflammatory, phenotype, mice, knockout, immune response, pathology, physiology Deletion, αvβ8, spontaneous, inflammatory, phenotype Deletion, αvβ8, spontaneous, inflammatory, phenotype
569	In adult tissue, most T cells are memory T cells. adult tissue, T cells, memory T cells adult tissue,memory T cells,T cells adult tissue, T cells, memory T cells adult tissue,memory T cells,T cells adult tissue,memory T cells,T cells
208	CHEK2 is not associated with breast cancer. CHEK2, breast cancer, genetic, mutation, BRCA1, BRCA2 CHEK2, breast cancer, genetic, mutation, association, BRCA1, BRCA2 CHEK2, breast cancer, genetic, mutation, association, research CHEK2, breast cancer, genetic, mutation, association, research, study, BRCA1, BRCA2 CHEK2, breast cancer, genetic testing, BRCA, mutation, tumor suppressor, association, genetic predisposition
690	Less than 10% of the gabonese children with Schimmelpenning-Feuerstein-Mims syndrome (SFM) had a plasma lactate of more than 5mmol/L. Gabonese, children, Schimmelpenning-Feuerstein-Mims, syndrome, SFM, plasma, lactate, mmol/L Schimmelpenning-Feuerstein-Mims, syndrome, Gabon, children, plasma, lactate, level Schimmelpenning-Feuerstein-Mims, syndrome, Gabon, children, plasma, lactate, level, percentage Gabonese, children, Schimmelpenning-Feuerstein-Mims, syndrome, SFM, plasma, lactate, percentage, threshold Gabonese, children, Schimmelpenning-Feuerstein-Mims, syndrome, SFM, plasma, lactate, mmol/L
691	Leukemia associated Rho guanine nucleotide-exchange factor represses RhoA in response to SRC activation. Leukemia, RhoGAP, RhoA, SRC, gene expression, signaling pathway, oncology, cell biology Leukemia, RhoGDS, RhoA, SRC, gene expression, signaling pathway Leukemia, Rho guanine nucleotide-exchange factor, RhoA, SRC activation Leukemia, Rho guanine nucleotide-exchange factor, RhoA, SRC activation Leukemia, RhoGAP, RhoA, SRC, gene regulation
692	Leuko-increased blood increases infectious complications in red blood cell transfusion. Leukocytes, blood transfusion, infectious complications, red blood cells, white blood cells Leukocytes,blood transfusion,infectious complications,red blood cells Leukocytes, transfusion, infection, complications, blood cells leukocytosis,blood transfusion,infectious complications,red blood cells Leukocytes,blood transfusion,infectious complications,red blood cells,leuko-infiltrated
1316	Transferred UCB T cells acquire a memory-like phenotype in recipients. Transferred, UCB, T cells, memory-like, phenotype, recipients T cells, transferred, UCB, memory-like, phenotype, recipients Transferred, UCB, T cells, memory-like, phenotype, recipients Transferred, UCB, T cells, memory-like, phenotype, recipients Transferred, UCB, T cells, acquire, memory-like, phenotype, recipients
693	Leuko-reduced blood reduces infectious complications in red blood cell transfusion. leuko-reduced, blood, infectious, complications, red, blood, cell, transfusion leuko-reduced, blood, infectious, complications, red, blood, cell, transfusion Leuko-reduced, blood, infectious, complications, red, blood, cell, transfusion Leuko-reduced, blood, infectious, complications, transfusion, red, cells leuko-reduced, blood, infectious, complications, red, blood, cell, transfusion
452	Gene expression does not vary appreciably across genetically identical cells. gene expression, genetically identical, cells, variation, appreciable gene expression, genetically identical cells, variability, cellular biology, molecular biology, genetics gene expression, genetically identical, cells, variability, consistent gene expression, genetically identical, cells, variation, minimal gene expression, genetically identical, cells, variability, negligible variation
212	CR is associated with higher methylation age. CR,methylation,age,diet,longevity,geneexpression,aging,senescence,caloricrestriction CR,methylation,age,senescence,longevity,dietary,restriction,nutrition,epigenetics CR,methylation,age,diet,longevity,epigenetics CR,methylation,age,diet,longevity,epigenetics,senescence CR,methylation,age,senescence,longevity,dietary,restriction,biomarker,gene_expression,aging
575	In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon. Saccharomyces_cerevisiae, whole_chromosome_aneuploidy, domesticated_populations, uncommon, genetics, yeast_genetics Saccharomyces,cerevisiae,domesticated,populations,whole,chromosome,aneuploidy,uncommon Saccharomyces,cerevisiae,whole,chromosome,aneuploidy,domesticated,populations,retrieval Saccharomyces_cerevisiae, whole_chromosome_aneuploidy, domesticated_populations, yeast_genetics Saccharomyces_cerevisiae, whole_chromosome_aneuploidy, domesticated_populations, yeast_genetics, chromosomal_abnormalities
213	CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery. CRP,mortality,CABG,surgery,predictive,value,coronary,artery,bypass,grafting CRP,mortality,CABG,surgery,prediction,coronary,artery,bypass,graft CRP, postoperative mortality, Coronary Artery Bypass Graft, CABG, predictive, surgery CRP, postoperative mortality, Coronary Artery Bypass Graft, CABG, predictive, surgery CRP, postoperative mortality, Coronary Artery Bypass Graft, CABG, predictive, surgery
577	In mice, P. chabaudi parasites are able to proliferate faster early in infection when inoculated at lower numbers than when inoculated at high numbers. P.chabaudi, mice, parasite proliferation, infection, inoculation number, early infection, parasite inoculation quantity mice,P,chabaudi,parasites,proliferation,infection,inoculation,numbers mice,P,chabaudi,parasites,proliferation,infection,inoculation,dosage,numbers P.chabaudi,mice,infection,parasite,proliferation,inoculation,dosage,immune response P.chabaudi, parasites, proliferation, mice, inoculation, number, infection
578	In mouse models, the loss of CSF1R facilitates MOZ-TIF2-induced leuekmogenesis. mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leuekmogenesis mouse models, CSF1R, loss, MOZ-TIF2, leukemia, leuekmogenesis
216	CX3CR1 on the Th2 cells impairs T cell survival CX3CR1,Th2,cells,T cell,survival,immunology,molecular biology,immune response,inflammation CX3CR1, Th2, T cells, survival, immunology, cytokines, inflammation, immune response CX3CR1,Th2,cells,T cell,survival,immunology,biology,inflammation,disease,immune response CX3CR1,Th2,cells,T cell,survival,biology,immunology,molecular biology,immune response,cell communication,immune regulation CX3CR1,Th2,cells,T细胞存活,immunity,inflammation,immune response
217	CX3CR1 on the Th2 cells promotes T cell survival CX3CR1,Th2,cells,T细胞生存,cytokines,immunity,inflammation CX3CR1,Th2,cells,T细胞存活,survival,免疫细胞,生物标志物,分子生物学,免疫学研究 CX3CR1,Th2,cells,T细胞存活,survival,免疫细胞,分子生物学 CX3CR1, Th2, T cell survival, immune response, cytokines, inflammation, immunology CX3CR1,Th2,cells,T细胞生存,CX3CR1受体,Th2免疫细胞,T细胞存活促进因子
338	Dexamethasone decreases risk of postoperative bleeding. Dexamethasone, postoperative bleeding, risk reduction, surgery, medication efficacy Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthesia, inflammatory response, corticosteroids Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthesia, inflammation, corticosteroid Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthesia, inflammation, corticosteroid Dexamethasone, postoperative bleeding, risk reduction, surgery, anesthesia, inflammation, corticosteroid
218	CX3CR1 on the Th2 cells promotes airway inflammation. CX3CR1, Th2, cells, airway, inflammation CX3CR1,Th2,cells,airway,inflammation,biomarker,immunology,asthma,mouse,model,immune response CX3CR1, Th2 cells, airway inflammation, immune response, asthma, cytokines, chemokines, immune regulation, inflammatory mediators CX3CR1, Th2, cells, airway, inflammation, immunology, cytokines, asthma, mouse, model, signaling CX3CR1,Th2,cells,airway,inflammation,molecular,biomarker,pathway,interaction,migration,immune response
219	CX3CR1 on the Th2 cells suppresses airway inflammation. CX3CR1, Th2 cells, airway inflammation, immune response, asthma, cytokines, immunology, inflammation, genetics, biomarker CX3CR1,Th2,cells,inflammation,airway,suppresses CX3CR1,Th2,cells,airway,inflammation,suppresses CX3CR1,Th2,cells,airway,inflammation,suppresses CX3CR1,Th2,cells,inflammation,airway,suppresses
1319	Transplanted human glial cells can differentiate within the host animal. transplanted, human, glial, cells, differentiate, host, animal transplantation, glial, cells, differentiation, host, animal, human transplant, glial, cells, differentiate, host, animal, human transplant, human, glial, cells, differentiation, host, animal transplanted, human, glial, cells, differentiate, host, animal
100	All hematopoietic stem cells segregate their chromosomes randomly. hematopoietic, stem, cells, chromosome, segregation, random, mitosis hematopoietic, stem, cells, chromosome, segregation, random, mitosis hematopoietic,stem,cells,chromosomes,randomly,segregate hematopoietic, stem, cells, chromosome, segregation, random, mitosis, biology, genetics hematopoietic, stem, cells, chromosome, segregation, random, biology
1204	The combination of H3K4me3 and H3K79me2 is found in quiescent hair follicle stem cells. H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,chromatin,mark,Epigenetics H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,chromatin,mark,markers,DNA,regulation,gene expression,proteins,methylation,biology,genetics,molecular biology,epigenetics,transcription,cell cycle,development,skin,regeneration,stem cell biology,chromatin modification,regulatory regions,transcriptome,genome,biomarker H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,DNA,methylation,chromatin,markers,geneexpression,proliferation,silencing H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,DNA,lysine,methylation,chromatin,marker,molecular,biochemistry,genetics,proteomics,expression,promoter,regulation,tissue,development,somatic,cancer,biology,epigenetics,transcription,factor,microscopy,analysis,study,experiment,marker,identification,characterization,marker,detection,marker,validation,marker,function,marker,maintenance,marker,dynamics,marker,mapping,marker,pattern,marker,landscape,marker H3K4me3,H3K79me2,quiescent,hair,follicle,stem,cells,chromatin,markers,regulation
343	Diabetic patients with acute coronary syndrome experience increased short-term and long-term risk for bleeding events. diabetes, acute coronary syndrome, bleeding, risk, diabetic patients, short-term, long-term diabetes, acute coronary syndrome, bleeding, diabetic patients, short-term risk, long-term risk diabetes, acute coronary syndrome, bleeding, risk, diabetic patients, short-term, long-term Diabetes, Acute Coronary Syndrome, Bleeding, Risk, Diabetic Patients, Short-term, Long-term Diabetes, Acute冠状动脉综合征, Bleeding风险, Short-term风险, Long-term风险
1202	The center of the granuloma in an immune cell induces a pro-inflammatory immune response. granuloma, immune cell, pro-inflammatory, response granuloma, immune cell, pro-inflammatory, center, immune response granuloma, immune cell, pro-inflammatory, center, immune response granuloma, immune cell, pro-inflammatory, center, immune response granuloma, immune cell, center, pro-inflammatory, response
587	In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, less than ten percent of the cells with green florescent colocalize with cell proliferation markers. transgenic,mice,green,florescent,protein,Sox2,promoter,cell,proliferation,markers,colocalize transgenic,mice,green,florescent,protein,Sox2,promoter,colocalize,cell,proliferation transgenic,mice,green,florescent,protein,Sox2,promoter,colocalize,cell,proliferation,markers transgenic,mice,green,florescent,protein,Sox2,promoter,cell,proliferation,colocalize transgenic,mice,green,florescent,protein,Sox2,promoter,colocalize,cell,proliferation,markers
1200	The binding orientation of the ML-SA1 activator at hTRPML2 is different from the binding orientation of the ML-SA1 activator at hTRPML1. binding orientation, ML-SA1 activator, hTRPML2, hTRPML1, protein activation, ligand binding, TRPML channels binding orientation, ML-SA1 activator, hTRPML2, hTRPML1, protein binding, TRPML channels binding orientation, ML-SA1 activator, hTRPML2, hTRPML1 binding orientation, ML-SA1 activator, hTRPML2, hTRPML1 binding orientation, ML-SA1 activator, hTRPML2, hTRPML1
589	In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events. ADHD, medications, cardiovascular, risk, adults, serious, events, current, remote, use ADHD, medications, cardiovascular, risk, events, young, middle-aged, adults, current, remote ADHD, medications, cardiovascular, events, risk, adults, young, middle-aged, current, remote ADHD, medications, cardiovascular, events, risk, young, middle-aged, adults, current, remote ADHD, medications, cardiovascular, risk, adults, serious, events, current, remote
1320	Transplanted human glial progenitor cells are incapable of forming a neural network with host animals' neurons. transplant, human, glial, progenitor, cells, neural, network, host, animals, neurons transplanted, human, glial, progenitor, cells, incapable, forming, neural, network, host, animals, neurons transplanted, human, glial, progenitor, cells, incapable, forming, neural, network, host, animals, neurons transplanted, human, glial, progenitor, cells, incapable, forming, neural, network, host, animals, neurons transplantation, glial, progenitor, cells, neural, network, host, animals, neurons
903	PD-1 triggering on monocytes reduces IL-10 production by monocytes. PD-1, monocytes, IL-10, production, immune, regulation PD-1, monocytes, IL-10, production, immune, response, immunology, cytokines, tumor, inflammation PD-1, monocytes, IL-10, immunology, cytokines, immune response PD-1, monocytes, IL-10, immunoregulation, cytokines, immune response PD-1, monocytes, IL-10, production, immune response
904	PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells. PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells PDPN,C-type lectin receptor,motility,stromal surfaces,actin cytoskeleton,dendritic cells
1207	The composition of myosin-II isoform switches from the polarizable B isoform to the more homogenous A isoform during hematopoietic differentiation. myosin-II, isoform, B, A, hematopoietic, differentiation, composition, polarization, homogeneity myosin-II, isoform, B, A, hematopoietic, differentiation, polarization, homogeneity myosin-II, isoform, B, A, hematopoietic, differentiation, composition, polarization, homogeneity myosin-II, isoform, hematopoietic, differentiation, B, A, polarity, switching myosin-II, isoform, B, A, hematopoietic, differentiation, polarization, homogeneity