--- name: life-sciences-connector description: Query PubMed and scientific databases for protocols, analyze biological data with Biopython, handle HIPAA-compliant data. Use for biology research, protocol searches, sequence analysis, or scientific data handling. Cross-validates sources for high accuracy. Triggers on "PubMed", "biology", "scientific data", "sequences", "protocols", "life sciences", "HIPAA". --- # Life Sciences Connector ## Purpose Connect to scientific databases (PubMed, Benchling) for protocol queries and biological data analysis with Biopython integration. ## When to Use - Biology research tasks - Protocol searches - Scientific data handling - Sequence analysis - Lab data integration - HIPAA-compliant workflows ## Core Instructions ### PubMed Query ```python from Bio import Entrez Entrez.email = "your.email@example.com" def search_pubmed(term, retmax=5): """Search PubMed for articles""" handle = Entrez.esearch(db="pubmed", term=term, retmax=retmax) record = Entrez.read(handle) return record['IdList'] def fetch_article(pmid): """Fetch article details""" handle = Entrez.efetch(db="pubmed", id=pmid, rettype="xml") return Entrez.read(handle) # Usage results = search_pubmed("CRISPR protocol") for pmid in results: article = fetch_article(pmid) print(article['Title']) ``` ### Sequence Analysis ```python from Bio import SeqIO from Bio.Align import PairwiseAligner # Parse FASTA sequences = list(SeqIO.parse("sequences.fasta", "fasta")) # Align sequences aligner = PairwiseAligner() alignments = aligner.align(sequences[0].seq, sequences[1].seq) print(f"Alignment score: {alignments[0].score}") ``` ### HIPAA Compliance ```python def anonymize_patient_data(data): """ Anonymize patient information (HIPAA) """ # Remove PHI (Protected Health Information) phi_fields = [ 'name', 'address', 'phone', 'email', 'ssn', 'medical_record_number' ] anonymized = data.copy() for field in phi_fields: if field in anonymized: anonymized[field] = hash_or_remove(field, data[field]) return anonymized ``` ## Guidelines - **Accuracy**: Cross-validate sources - **Privacy**: Anonymize patient data (HIPAA) - **Citations**: Always cite sources - **Verification**: Cross-check protocols ## Dependencies - Python 3.8+ - biopython - requests - PubMed Entrez API access ## Version v1.0.0 (2025-10-23)