---
name: Psilacetin
molecule: C14H18N2O2
compound: "O-Acetylpsilocin"
era: Modern
origin: Switzerland
archetype: Acidhouse
ancestor: Irish Druids, Buddhist, Sami
swag_score: 4
image: "https://assets.0xhoneyjar.xyz/Mibera/traits/acidhouse_irishDruids_buddhists_sami_psilacetin.webp"
date_added: "2025-01-12"
---

<div align="center">
  <img src="https://assets.0xhoneyjar.xyz/Mibera/traits/acidhouse_irishDruids_buddhists_sami_psilacetin.webp" alt="Psilacetin" width="320" />
</div>


# Psilacetin

## Effects & Properties

**Effects:** Vivid visual and auditory hallucinations, euphoria, and altered
perception of time and space.

**Natural Occurrence:** Psilacetin is a synthetic compound and
does not occur naturally. Used primarily recreationally for psychedelic experiences in spiritual or
social settings.

## History

Psilacetin (4-AcO-DMT, or O-acetylpsilocin) was first synthesized by Albert Hofmann and Franz Troxler at Sandoz Laboratories in Switzerland in 1963 as part of their research into psilocybin analogs. It remained relatively obscure for decades until the rise of the online research chemical market in the 2000s, where it was sold as a legal psilocybin prodrug that converts to psilocin in the body. Psilacetin became popular in psychedelic communities for its mushroom-like effects and more consistent dosing compared to natural psilocybin mushrooms, and it occupies a legal gray area in many countries.

## Connections

**Archetype:** [Acidhouse](../../../core-lore/archetypes.md#acidhouse)

**Ancestor:** [Irish Druids](../../../core-lore/ancestors/irish-druids.md), [Buddhist](../../../core-lore/ancestors/buddhist.md), [Sami](../../../core-lore/ancestors/sami.md)

**Tarot Card:** [The High Priestess](../../../core-lore/tarot-cards/the-high-priestess.md)

**PubChem:** [O-Acetylpsilocin](https://pubchem.ncbi.nlm.nih.gov/compound/O-Acetylpsilocin)

## Sources

- https://www.drugs.com/illicit/psilacetin.html
- https://erowid.org/chemicals/4_aco_dmt/4_aco_dmt.shtml
- [4-AcO-DMT - Wikipedia](https://en.wikipedia.org/wiki/4-AcO-DMT)
- [In vivo validation of psilacetin as a prodrug - Frontiers in Psychiatry](https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1303365/full)
- [Tentative identification of in vitro metabolites of O-acetylpsilocin - PubMed](https://pubmed.ncbi.nlm.nih.gov/35312166/)