---
name: Sober
molecule: C10H12N2O
compound: "Serotonin"
era: Ancient
origin: null
archetype: Milady
ancestor: Mongolian
swag_score: 2
image: "https://assets.0xhoneyjar.xyz/Mibera/traits/milady_mongolian_sober.webp"
date_added: "2025-01-12"
---

<div align="center">
  <img src="https://assets.0xhoneyjar.xyz/Mibera/traits/milady_mongolian_sober.webp" alt="Sober" width="320" />
</div>


# Sober

## Effects & Properties

**Effects:** Promotes feelings of happiness, production of melatonin,
increased appetite, and mitigates anxiety and stress.

**Natural Occurrence:** **Appearance:**

## History

Serotonin was first identified in 1948 by Maurice Rapport, Arda Green, and Irvine Page at the Cleveland Clinic, who isolated it from blood serum and named it for its vasoconstrictive properties (serum tonic). Its role as a neurotransmitter in the brain was established in the 1950s by Betty Twarog and Irvine Page. The understanding that endogenous serotonin regulates mood, sleep, appetite, and well-being has been foundational to modern psychiatry, leading to the development of SSRIs in the 1980s and reshaping how humanity understands the neurochemistry of baseline contentment and emotional resilience.

## Connections

**Archetype:** [Milady](../../../core-lore/archetypes.md#milady)

**Ancestor:** [Mongolian](../../../core-lore/ancestors/mongolian.md)

**Tarot Card:** [Ace of Pentacles](../../../core-lore/tarot-cards/ace-of-pentacles.md)

**PubChem:** [Serotonin](https://pubchem.ncbi.nlm.nih.gov/compound/Serotonin)

**Paired With:** [Euphoria](euphoria.md), [Clear Pill](clear-pill.md)

## Sources

- https://www.webmd.com/depression/video/video-serotonin-effects
- https://www.healthline.com/health/mental-health/serotonin
- [Serotonin - Wikipedia](https://en.wikipedia.org/wiki/Serotonin) — discovery in 1948 by Maurice Rapport, Arda Green, and Irvine Page at Cleveland Clinic; named from serum + tonic; role as neurotransmitter
- [Maurice M. Rapport - Wikipedia](https://en.wikipedia.org/wiki/Maurice_M._Rapport) — isolation of serotonin from blood serum
- [Betty Twarog - Wikipedia](https://en.wikipedia.org/wiki/Betty_Twarog) — first discovery of serotonin in mammalian brain (1952-1953)
- [Development and discovery of SSRI drugs - Wikipedia](https://en.wikipedia.org/wiki/Development_and_discovery_of_SSRI_drugs) — SSRI development in the 1980s