NMDC Ontology
type: Ontology
version IRI: nmdco.owl
description: The NMDC Ontology (NMDCO) is used by the National Micrbiome Data Collaborative (NMDC, https://microbiomedata.org) to annotate multi-omic microbiome metadata. It merges a number of ontologies relevant to the NMDC (such as the plant and environment ontologies) into a single ontology. It is maintained using Github at https://github.com/microbiomedata/nmdc-ontology. Please use this GitHub repository's Issue tracker to request new terms/classes or report errors or specific concerns related to the ontology.
creator: Bill Duncan (https://orcid.org/0000-0001-9625-1899)
license: https://creativecommons.org/publicdomain/zero/1.0/
version info: 2024-03-15

editor preferred term~editor preferred label
type: AnnotationProperty
editor preferred term~editor preferred label: editor preferred term
has curation status: IAO_0000122
definition: The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
label: editor preferred term

example of usage
type: AnnotationProperty
editor preferred term~editor preferred label: example of usage
has curation status: IAO_0000122
definition: A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

has curation status
type: AnnotationProperty
editor preferred term~editor preferred label: has curation status
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Bill Bug
term editor: PERSON:Melanie Courtot

definition
type: AnnotationProperty
editor preferred term~editor preferred label: definition
has curation status: IAO_0000122
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
editor note: 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

editor note
type: AnnotationProperty
editor preferred term~editor preferred label: editor note
has curation status: IAO_0000122
definition: An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obofoundry.org/obo/obi>
database_cross_reference: IAO:0000116
has_obo_namespace: uberon
id: editor_note
is metadata tag: true
shorthand: editor_note

term editor
type: AnnotationProperty
editor preferred term~editor preferred label: term editor
has curation status: IAO_0000122
definition: Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people
editor note: 20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

alternative term
type: AnnotationProperty
editor preferred term~editor preferred label: alternative label
has curation status: IAO_0000125
definition: A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like.
term editor: OBO Operations committee
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
comment: Consider re-defing to: An alternative name for a class or property which can mean the same thing as the preferred name (semantically equivalent, narrow, broad or related).
label: alternative label

definition source
type: AnnotationProperty
editor preferred term~editor preferred label: definition source
has curation status: IAO_0000122
definition: Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007
term editor: PERSON:Daniel Schober
definition source: Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

has obsolescence reason
type: AnnotationProperty
editor preferred term~editor preferred label: has obsolescence reason
definition: Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification.
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Melanie Courtot

curator note
type: AnnotationProperty
editor preferred term~editor preferred label: curator note
has curation status: IAO_0000122
definition: An administrative note of use for a curator but of no use for a user
term editor: PERSON:Alan Ruttenberg

term tracker item
type: AnnotationProperty
editor preferred term~editor preferred label: term tracker item
example of usage: the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/
has curation status: IAO_0000125
definition: An IRI or similar locator for a request or discussion of an ontology term.
term editor: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
definition source: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
comment: The 'tracker item' can associate a tracker with a specific ontology term.

ontology term requester
type: AnnotationProperty
editor preferred term~editor preferred label: ontology term requester
has curation status: IAO_0000125
definition: The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition.
term editor: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
definition source: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
comment: The 'term requester' can credit the person, organization or project who request the ontology term.

imported from
type: AnnotationProperty
editor preferred term~editor preferred label: imported from
has curation status: IAO_0000125
definition: For external terms/classes, the ontology from which the term was imported
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Melanie Courtot
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

expand expression to
type: AnnotationProperty
editor preferred term~editor preferred label: expand expression to
example of usage: ObjectProperty: RO_0002104 Label: has plasma membrane part Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)"
definition: A macro expansion tag applied to an object property (or possibly a data property) which can be used by a macro-expansion engine to generate more complex expressions from simpler ones
term editor: Chris Mungall

expand assertion to
type: AnnotationProperty
editor preferred term~editor preferred label: expand assertion to
example of usage: ObjectProperty: RO??? Label: spatially disjoint from Annotations: expand_assertion_to "DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X) (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)"
definition: A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom.
term editor: Chris Mungall

first order logic expression
type: AnnotationProperty
editor preferred term~editor preferred label: first order logic expression
definition: An assertion that holds between an OWL Object Property and a string or literal, where the value of the string or literal is a Common Logic sentence of collection of sentences that define the Object Property.
term editor: PERSON:Alan Ruttenberg
sub property of: logical macro assertion on an object property

OBO foundry unique label
type: AnnotationProperty
editor preferred term~editor preferred label: OBO foundry unique label
has curation status: IAO_0000125
definition: An alternative name for a class or property which is unique across the OBO Foundry.
editor note: The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools .
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Bjoern Peters
term editor: PERSON:Chris Mungall
term editor: PERSON:Melanie Courtot
definition source: GROUP:OBO Foundry <http://obofoundry.org/>

elucidation
type: AnnotationProperty
editor preferred term~editor preferred label: elucidation
term editor: person:Alan Ruttenberg
definition source: Person:Barry Smith
elucidation: Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms

has associated axiom(nl)
type: AnnotationProperty
editor preferred term~editor preferred label: has associated axiom(nl)
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: An axiom associated with a term expressed using natural language

has associated axiom(fol)
type: AnnotationProperty
editor preferred term~editor preferred label: has associated axiom(fol)
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: An axiom expressed in first order logic using CLIF syntax

has ontology root term
type: AnnotationProperty
editor preferred term~editor preferred label: has ontology root term
definition: Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root.
term editor: Nicolas Matentzoglu

scheduled for obsoletion on or after
type: AnnotationProperty
editor preferred term~editor preferred label: scheduled for obsoletion on or after
definition: Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date.
term editor: Chris Mungall, Jie Zheng

has axiom label
type: AnnotationProperty
editor preferred term~editor preferred label: has axiom id
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI

term replaced by
type: AnnotationProperty
editor preferred term~editor preferred label: term replaced by
has curation status: IAO_0000125
definition: Use on obsolete terms, relating the term to another term that can be used as a substitute
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
comment: Add as annotation triples in the granting ontology

defined by construct
type: AnnotationProperty
example of usage: 'part disjoint with' 'defined by construct' """ PREFIX owl: <http://www.w3.org/2002/07/owl#> PREFIX : <http://example.org/ CONSTRUCT { [ a owl:Restriction ; owl:onProperty :part_of ; owl:someValuesFrom ?a ; owl:disjointWith [ a owl:Restriction ; owl:onProperty :part_of ; owl:someValuesFrom ?b ] ] } WHERE { ?a :part_disjoint_with ?b . }
definition: Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation.
term tracker item: https://github.com/ontodev/robot/issues/963
contributor: https://orcid.org/0000-0002-7356-1779
contributor: https://orcid.org/0000-0002-8688-6599

plural form
type: AnnotationProperty
example of usage: CHEBI:23367 (molecular entity) has an exact synonym (molecular entities), which is of the type OMO:0003004 (plural form)
definition: A synonym type for describing pluralization synonyms
contributor: https://orcid.org/0000-0003-4423-4370
sub property of: synonym_type_property

temporal interpretation
type: AnnotationProperty
definition: An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.
sub property of: logical macro assertion on an object property

never in taxon
type: AnnotationProperty
example of usage: tooth SubClassOf 'never in taxon' value 'Aves'
definition: x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/17921072
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20973947
expand assertion to: Class: ?X DisjointWith: RO_0002162 some ?Y
defined by construct: PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#> PREFIX owl: <http://www.w3.org/2002/07/owl#> PREFIX in_taxon: <http://purl.obolibrary.org/obo/RO_0002162> PREFIX never_in_taxon: <http://purl.obolibrary.org/obo/RO_0002161> CONSTRUCT { in_taxon: a owl:ObjectProperty . ?x owl:disjointWith [ a owl:Restriction ; owl:onProperty in_taxon: ; owl:someValuesFrom ?taxon ] . ?x rdfs:subClassOf [ a owl:Restriction ; owl:onProperty in_taxon: ; owl:someValuesFrom [ a owl:Class ; owl:complementOf ?taxon ] ] . } WHERE { ?x never_in_taxon: ?taxon . }
sub property of: taxonomic class assertion

mutually spatially disjoint with
type: AnnotationProperty
definition: A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B.
alternative term: non-overlapping with
alternative term: shares no parts with
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
expand assertion to: Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)
defined by construct: PREFIX owl: <http://www.w3.org/2002/07/owl#> PREFIX part_of: <http://purl.obolibrary.org/obo/BFO_0000050> PREFIX mutually_spatially_disjoint_with: <http://purl.obolibrary.org/obo/RO_0002171> CONSTRUCT { part_of: a owl:ObjectProperty . [ a owl:Restriction ; owl:onProperty part_of: ; owl:someValuesFrom ?x ; owl:disjointWith [ a owl:Restriction ; owl:onProperty part_of: ; owl:someValuesFrom ?y ] ] } WHERE { ?x mutually_spatially_disjoint_with: ?y . }
sub property of: logical macro assertion on a class

taxonomic class assertion
type: AnnotationProperty
definition: An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon.
sub property of: logical macro assertion on a class

ambiguous for taxon
type: AnnotationProperty
definition: S ambiguous_for_taxon T if the class S does not have a clear referent in taxon T. An example would be the class 'manual digit 1', which encompasses a homology hypotheses that is accepted for some species (e.g. human and mouse), but does not have a clear referent in Aves - the referent is dependent on the hypothesis embraced, and also on the ontogenetic stage. [PHENOSCPAE:asilomar_mtg]
sub property of: taxonomic class assertion

dubious for taxon
type: AnnotationProperty
definition: S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
comment: This relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take ongoing coordinated effort to resolve. Example: metencephalon in teleost
sub property of: taxonomic class assertion

present in taxon
type: AnnotationProperty
definition: S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
defined by construct: PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#> PREFIX owl: <http://www.w3.org/2002/07/owl#> PREFIX in_taxon: <http://purl.obolibrary.org/obo/RO_0002162> PREFIX present_in_taxon: <http://purl.obolibrary.org/obo/RO_0002175> CONSTRUCT { in_taxon: a owl:ObjectProperty . ?witness rdfs:label ?label . ?witness rdfs:subClassOf ?x . ?witness rdfs:subClassOf [ a owl:Restriction ; owl:onProperty in_taxon: ; owl:someValuesFrom ?taxon ] . } WHERE { ?x present_in_taxon: ?taxon . BIND(IRI(CONCAT( "http://purl.obolibrary.org/obo/RO_0002175#", MD5(STR(?x)), "-", MD5(STR(?taxon)) )) as ?witness) BIND(CONCAT(STR(?x), " in taxon ", STR(?taxon)) AS ?label) }
comment: The SPARQL expansion for this relation introduces new named classes into the ontology. For this reason it is likely that the expansion should only be performed during a QC pipeline; the expanded output should usually not be included in a published version of the ontology.
sub property of: taxonomic class assertion

defined by inverse
type: AnnotationProperty
sub property of: subset_property

logical macro assertion
type: AnnotationProperty
definition: An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.

annotation property cardinality
type: AnnotationProperty
definition: An assertion that holds between an OWL Annotation Property P and a non-negative integer N, with the interpretation: for any P(i j) it must be the case that | { k : P(i k) } | = N.
sub property of: logical macro assertion on an annotation property
range: nonNegativeInteger

logical macro assertion on a class
type: AnnotationProperty
definition: A logical macro assertion whose domain is an IRI for a class
editor note: The domain for this class can be considered to be owl:Class, but we cannot assert this in OWL2-DL
sub property of: logical macro assertion

logical macro assertion on a property
type: AnnotationProperty
definition: A logical macro assertion whose domain is an IRI for a property
sub property of: logical macro assertion

logical macro assertion on an object property
type: AnnotationProperty
definition: Used to annotate object properties to describe a logical meta-property or characteristic of the object property.
sub property of: logical macro assertion on a property

logical macro assertion on an annotation property
type: AnnotationProperty
sub property of: logical macro assertion on a property

dispositional interpretation
type: AnnotationProperty
definition: An assertion that holds between an OWL Object Property and a dispositional interpretation that elucidates how OWL Class Axioms or OWL Individuals that use this property are to be interpreted in a dispositional context. For example, A binds B may be interpreted as A have a mutual disposition that is realized by binding to the other one.
sub property of: logical macro assertion on an object property

has no connections with
type: AnnotationProperty
example of usage: 'pectoral appendage skeleton' has no connections with 'pelvic appendage skeleton'
definition: A is has_no_connections_with B if there are no parts of A or B that have a connection with the other.
alternative term: shares no connection with
expand assertion to: Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (RO_0002170 some (BFO_0000050 some ?Y))
sub property of: logical macro assertion on a class

inherited annotation property
type: AnnotationProperty

curator guidance link
type: AnnotationProperty
definition: Connects an ontology entity (class, property, etc) to a URL from which curator guidance can be obtained. This assertion is inherited in the same manner as functional annotations (e.g. for GO, over SubClassOf and part_of)
sub property of: inherited annotation property

always present in taxon
type: AnnotationProperty
example of usage: brain always_present_in_taxon 'Vertebrata'
example of usage: forelimb always_present_in_taxon Euarchontoglires
definition: S always_present_in_taxon T if every fully formed member of taxon T has part some S, or is an instance of S
editor note: This is a very strong relation. Often we will not have enough evidence to know for sure that there are no species within a lineage that lack the structure - loss is common in evolution. However, there are some statements we can make with confidence - no vertebrate lineage could persist without a brain or a heart. All primates are limbed.
alternative term: never lost in
sub property of: present in taxon

temporal logical macro assertion on a class
type: AnnotationProperty
curator note: This properties were created originally for the annotation of developmental or life cycle stages, such as for example Carnegie Stage 20 in humans.
sub property of: logical macro assertion on a class

measurement property has unit
type: AnnotationProperty
sub property of: logical macro assertion on an annotation property

has start time value
type: AnnotationProperty
sub property of: temporal logical macro assertion on a class

has end time value
type: AnnotationProperty
sub property of: temporal logical macro assertion on a class

start, days post fertilization
type: AnnotationProperty
definition: Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property.
sub property of: has start time value

end, days post fertilization
type: AnnotationProperty
definition: Count of number of days intervening between the end of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 1 for this property.
sub property of: has end time value

start, years post birth
type: AnnotationProperty
definition: Count of number of years intervening between the start of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 0 for this property, and the period during which the child is one year old has the value 1.
sub property of: has start time value

end, years post birth
type: AnnotationProperty
definition: Count of number of years intervening between the end of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 1 for this property, and the period during which the child is one year old has the value 2
sub property of: has end time value

start, months post birth
type: AnnotationProperty
definition: Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the child is one month old has the value 1.
sub property of: has start time value

end, months post birth
type: AnnotationProperty
definition: Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the child is one month old has the value 2
sub property of: has end time value

month of gestation
type: AnnotationProperty
definition: Defines the start and end of a stage with a duration of 1 month, relative to either the time of fertilization or last menstrual period of the mother (to be clarified), counting from one, in terms of a reference model. Thus if month_of_gestation=3, then the stage is 2 month in.
sub property of: temporal logical macro assertion on a class

has developmental stage marker
type: AnnotationProperty
definition: A relationship between a stage class and an anatomical structure or developmental process class, in which the stage is characterized by the appearance of the structure or the occurrence of the biological process
sub property of: temporal logical macro assertion on a class

start, days post coitum
type: AnnotationProperty
definition: Count of number of days intervening between the start of the stage and the time of coitum.
curator note: For mouse staging: assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)
sub property of: has start time value

end, days post coitum
type: AnnotationProperty
definition: Count of number of days intervening between the end of the stage and the time of coitum.
sub property of: has end time value

start, weeks post birth
type: AnnotationProperty
sub property of: has start time value

end, weeks post birth
type: AnnotationProperty
sub property of: has end time value

is asymmetric relational form of process class
type: AnnotationProperty
definition: If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x subject-partner-in p, y object-partner-in p
sub property of: is relational form of process class

is symmetric relational form of process class
type: AnnotationProperty
definition: If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x partner-in p, y partner-in p
sub property of: is relational form of process class

is relational form of process class
type: AnnotationProperty
definition: R is the relational form of a process if and only if either (1) R is the symmetric relational form of a process or (2) R is the asymmetric relational form of a process
sub property of: is relational form of a class

is direct form of
type: AnnotationProperty
definition: relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y
editor note: The general property hierarchy is: "directly P" SubPropertyOf "P" Transitive(P) Where we have an annotation assertion "directly P" "is direct form of" "P"
logical macro assertion on an annotation property: If we have the annotation P is-direct-form-of Q, and we have inverses P' and Q', then it follows that P' is-direct-form-of Q'
creator: https://orcid.org/0000-0002-6601-2165
sub property of: logical macro assertion on an object property

is indirect form of
type: AnnotationProperty
definition: relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y
creator: https://orcid.org/0000-0002-6601-2165
sub property of: logical macro assertion on an object property

logical macro assertion on an axiom
type: AnnotationProperty
sub property of: logical macro assertion

is a defining property chain axiom
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL
sub property of: logical macro assertion on an axiom

is a defining property chain axiom where second argument is reflexive
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.
sub property of: is a defining property chain axiom

is relational form of a class
type: AnnotationProperty
definition: An annotation property that connects an object property to a class, where the object property is derived from or a shortcut property for the class. The exact semantics of this annotation may vary on a case by case basis.
sub property of: logical macro assertion on an object property

logical macro assertion involving identity
type: AnnotationProperty
definition: A shortcut relationship that holds between two entities based on their identity criteria
sub property of: logical macro assertion

in approximate one to one relationship with
type: AnnotationProperty
definition: A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds.
sub property of: logical macro assertion involving identity

is approximately equivalent to
type: AnnotationProperty
definition: x is approximately equivalent to y if it is the case that x is equivalent, identical or near-equivalent to y
curator note: The precise meaning of this property is dependent upon some contexts. It is intended to group multiple possible formalisms. Possibilities include a probabilistic interpretation, for example, Pr(x=y) > 0.95. Other possibilities include reified statements of belief, for example, "Database D states that x=y"
sub property of: in approximate one to one relationship with

is opposite of
type: AnnotationProperty
example of usage: 'anterior end of organism' is-opposite-of 'posterior end of organism'
example of usage: 'increase in temperature' is-opposite-of 'decrease in temperature'
definition: x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).
sub property of: in approximate one to one relationship with

is indistinguishable from
type: AnnotationProperty
definition: x is indistinguishable from y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).
sub property of: is approximately equivalent to

evidential logical macro assertion on an axiom
type: AnnotationProperty
sub property of: logical macro assertion on an axiom

axiom has evidence
type: AnnotationProperty
definition: A relationship between a sentence and an instance of a piece of evidence in which the evidence supports the axiom
curator note: This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual.
sub property of: evidential logical macro assertion on an axiom

axiom contradicted by evidence
type: AnnotationProperty
definition: A relationship between a sentence and an instance of a piece of evidence in which the evidence contradicts the axiom
curator note: This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual.
sub property of: evidential logical macro assertion on an axiom

is representative IRI for equivalence set
type: AnnotationProperty
example of usage: In the context of a particular project, the IRI with CURIE NCBIGene:64327 (which in this example denotes a class) is considered to be representative. This means that if we have equivalent classes with IRIs OMIM:605522, ENSEMBL:ENSG00000105983, HGNC:13243 forming an equivalence set, the NCBIGene is considered the representative member IRI. Depending on the policies of the project, the classes may be merged, or the NCBIGene IRI may be chosen as the default in a user interface context.
definition: this property relates an IRI to the xsd boolean value "True" if the IRI is intended to be the representative IRI for a collection of classes that are mutually equivalent.
curator note: If it is necessary to make the context explicit, an axiom annotation can be added to the annotation assertion
see also: OWLAPI Reasoner documentation for representativeElement, which follows a similar idea, but selects an arbitrary member
sub property of: logical macro assertion involving identity

nominally disjoint with
type: AnnotationProperty
definition: true if the two properties are disjoint, according to OWL semantics. This should only be used if using a logical axiom introduces a non-simple property violation.
creator: https://orcid.org/0000-0002-6601-2165
sub property of: logical macro assertion on an object property

is directional form of
type: AnnotationProperty
definition: Used to annotate object properties representing a causal relationship where the value indicates a direction. Should be "+", "-" or "0"
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-03-13T23:59:29Z
sub property of: logical macro assertion on an object property

is positive form of
type: AnnotationProperty
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-03-14T00:03:16Z
sub property of: is directional form of

is negative form of
type: AnnotationProperty
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-03-14T00:03:24Z
sub property of: is directional form of

is homeomorphic for
type: AnnotationProperty
example of usage: part-of is homeomorphic for independent continuants.
definition: R is homemorphic for C iff (1) there exists some x,y such that x R y, and x and y instantiate C and (2) for all x, if x is an instance of C, and there exists some y some such that x R y, then it follows that y is an instance of C.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-10-21T19:46:34Z
comment: R homeomorphic-for C expands to: C SubClassOf R only C. Additionally, for any class D that is disjoint with C, we can also expand to C DisjointWith R some D, D DisjointWith R some C.
sub property of: logical macro assertion on an object property

valid_for_go_annotation_extension
type: AnnotationProperty
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-09-22T11:05:29Z
sub property of: subset_property

valid_for_go_gp2term
type: AnnotationProperty
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-09-22T11:05:18Z
sub property of: subset_property

valid_for_go_ontology
type: AnnotationProperty
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-09-22T11:04:12Z
sub property of: subset_property

valid_for_gocam
type: AnnotationProperty
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-09-22T11:05:45Z
sub property of: subset_property

EnvO-Lite-GSC
type: AnnotationProperty
comment: EnvO-Lite-GSC
sub property of: subset_property

disconnected_from
type: AnnotationProperty
definition: A is disconnected_from B if they have no parts in common.
expand assertion to: Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)
has_exact_synonym: non_overlapping_with
has_obo_namespace: ENVO
id: disconnected_from
is class level: true
is metadata tag: true

Axiom
annotated source: disconnected_from
annotated property: definition
annotated target: A is disconnected_from B if they have no parts in common.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

disposition slim
type: AnnotationProperty
comment: Disposition slim
sub property of: subset_property

environmental hazards
type: AnnotationProperty
comment: environmental_hazards
sub property of: subset_property

envoANZSoil
type: AnnotationProperty
comment: envoANZSoil
sub property of: subset_property

envoAstro
type: AnnotationProperty
comment: envoAstro
sub property of: subset_property

envoAtmo
type: AnnotationProperty
comment: envoAtmo
sub property of: subset_property

envoCesab
type: AnnotationProperty
comment: envoCesab
sub property of: subset_property

envoCmecs
type: AnnotationProperty
comment: envoCmecs
sub property of: subset_property

envoEOVs
type: AnnotationProperty
comment: envoEOVs
sub property of: subset_property

envoEmpo
type: AnnotationProperty
comment: envoEmpo
sub property of: subset_property

envoMarine
type: AnnotationProperty
comment: envoMarine
sub property of: subset_property

envoMeo
type: AnnotationProperty
comment: envoMeo
sub property of: subset_property

envoNceas
type: AnnotationProperty
comment: envoNceas
sub property of: subset_property

envoOmics
type: AnnotationProperty
comment: envoOmics
sub property of: subset_property

envoPlastics
type: AnnotationProperty
comment: envoPlastics
sub property of: subset_property

envoPolar
type: AnnotationProperty
comment: envoPolar
sub property of: subset_property

mpath slim
type: AnnotationProperty
comment: Pathology slim
sub property of: subset_property

nlcd2011
type: AnnotationProperty
comment: nlcd2011
sub property of: subset_property

relational slim
type: AnnotationProperty
comment: Relational slim: types of quality that require an additional entity in order to exist
sub property of: subset_property

ro-eco
type: AnnotationProperty
comment: ro-eco
sub property of: subset_property

scalar slim
type: AnnotationProperty
comment: Scalar slim
sub property of: subset_property

value slim
type: AnnotationProperty
comment: Value slim
sub property of: subset_property

wwfBiome
type: AnnotationProperty
comment: wwfBiome
sub property of: subset_property

Angiosperm
type: AnnotationProperty
comment: Term for angiosperms
sub property of: subset_property

Arabidopsis
type: AnnotationProperty
comment: Term used for Arabidopsis
sub property of: subset_property

Bryophytes
type: AnnotationProperty
comment: Term used for mosses, liverworts, and/or hornworts
sub property of: subset_property

CL
type: AnnotationProperty
comment: plant cells
sub property of: subset_property

Citrus
type: AnnotationProperty
comment: Term used for citrus
sub property of: subset_property

German synonym (exact)
type: AnnotationProperty
has_scope: has_exact_synonym
sub property of: synonym_type_property

Gymnosperms
type: AnnotationProperty
comment: Term used for gymnosperms
sub property of: subset_property

Japanese synonym (exact)
type: AnnotationProperty
has_scope: has_exact_synonym
sub property of: synonym_type_property

Maize
type: AnnotationProperty
comment: Term used for maize
sub property of: subset_property

Musa
type: AnnotationProperty
comment: Terms used for banana
sub property of: subset_property

Poaceae
type: AnnotationProperty
comment: Term used for grasses
sub property of: subset_property

Potato
type: AnnotationProperty
comment: Term used for potato
sub property of: subset_property

Pteridophytes
type: AnnotationProperty
comment: Term used for ferns and allies
sub property of: subset_property

Rice
type: AnnotationProperty
comment: Term used for rice
sub property of: subset_property

Spanish synonym (exact)
type: AnnotationProperty
has_scope: has_exact_synonym
sub property of: synonym_type_property

Tomato
type: AnnotationProperty
comment: Term used for tomato
sub property of: subset_property

TraitNet
type: AnnotationProperty
comment: Plant Functional Traits
sub property of: subset_property

reference
type: AnnotationProperty
comment: reference plant structure term
sub property of: subset_property

eco subset
type: AnnotationProperty
sub property of: subset_property

subset_property
type: AnnotationProperty

synonym_type_property
type: AnnotationProperty

consider
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

has_broad_synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has a more general meaning than the preferred name/primary label.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/18
label: has broad synonym
sub property of: alternative term

database_cross_reference
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has the exact same meaning than the preferred name/primary label.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/20
label: has exact synonym
sub property of: alternative term

has_narrow_synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has a more specific meaning than the preferred name/primary label.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/19
label: has narrow synonym
sub property of: alternative term

has_obo_format_version
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty
definition: An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/21
label: has related synonym
sub property of: alternative term

has_scope
type: AnnotationProperty

has_synonym_type
type: AnnotationProperty

in_subset
type: AnnotationProperty

shorthand
type: AnnotationProperty

treat-xrefs-as-genus-differentia
type: AnnotationProperty

treat-xrefs-as-is_a
type: AnnotationProperty

isDefinedBy
OBO foundry unique label: is defined by

Axiom
annotated source: isDefinedBy
annotated property: OBO foundry unique label
annotated target: is defined by
comment: This is an experimental annotation

see also
type: AnnotationProperty
has_obo_namespace: spatial
has_obo_namespace: uberon
id: seeAlso
is metadata tag: true
shorthand: seeAlso

part of
type: ObjectProperty
sub property of: overlaps
inverse of: has part
type: TransitiveProperty
editor preferred term~editor preferred label: is part of
example of usage: my brain is part of my body (continuant parthood, two material entities)
example of usage: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
example of usage: this day is part of this year (occurrent parthood)
definition: a core relation that holds between a part and its whole
editor note: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
alternative term: part_of
temporal interpretation: RO_0001901
is homeomorphic for: continuant
is homeomorphic for: occurrent
is homeomorphic for: independent continuant
is homeomorphic for: realizable
is homeomorphic for: quality
is homeomorphic for: characteristic
is homeomorphic for: generically dependent continuant
database_cross_reference: BFO:0000050
has_obo_namespace: plant_ontology
has_obo_namespace: quality
has_obo_namespace: spatial
has_obo_namespace: uberon
id: part_of
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_gp2term
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: part_of
label: part_of

has part
type: ObjectProperty
sub property of: overlaps
type: TransitiveProperty
editor preferred term~editor preferred label: has part
example of usage: my body has part my brain (continuant parthood, two material entities)
example of usage: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
example of usage: this year has part this day (occurrent parthood)
definition: a core relation that holds between a whole and its part
editor note: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
alternative term: has_part
temporal interpretation: RO_0001901
database_cross_reference: BFO:0000051
has_obo_namespace: plant_ontology
has_obo_namespace: quality
has_obo_namespace: spatial
has_obo_namespace: uberon
id: has_part
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: has_part
label: has_part

realized in
type: ObjectProperty
inverse of: realizes
domain: realizable
range: process
editor preferred term~editor preferred label: realized in
example of usage: this disease is realized in this disease course
example of usage: this fragility is realized in this shattering
example of usage: this investigator role is realized in this investigation
alternative term: is realized by
alternative term: realized_in
elucidation: [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

realizes
type: ObjectProperty
domain: process
range: realizable
editor preferred term~editor preferred label: realizes
example of usage: this disease course realizes this disease
example of usage: this investigation realizes this investigator role
example of usage: this shattering realizes this fragility
elucidation: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

preceded by
type: ObjectProperty
sub property of: ends after
inverse of: precedes
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
property chain axiom: starts during
property chain axiom: happens during
editor preferred term~editor preferred label: preceded by
definition: The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P.
definition: x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
editor note: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
alternative term: is preceded by
alternative term: preceded_by
source: http://www.obofoundry.org/ro/#OBO_REL:preceded_by
created by: Laurel_Cooper
creation date: 2013-07-09T14:29:15Z
database_cross_reference: BFO:0000062
has_obo_namespace: plant_ontology
has_obo_namespace: uberon
id: preceded_by
in_subset: eco subset
shorthand: preceded_by
comment: Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
label: preceded_by

Axiom
annotated source: preceded by
annotated property: definition
annotated target: The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P.
database_cross_reference: POC:Laurel_Cooper

precedes
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
domain: occurrent
range: occurrent
property chain axiom: part of
property chain axiom: happens during
editor preferred term~editor preferred label: precedes
definition: x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
created by: Laurel_Cooper
creation date: 2015-06-04T17:18:40Z
database_cross_reference: BFO:0000063
has_obo_namespace: plant_ontology
has_obo_namespace: uberon
id: precedes
in_subset: eco subset
shorthand: precedes

occurs in
type: ObjectProperty
inverse of: contains process
domain: occurrent
domain: process
range: independent continuant
property chain axiom: part of
editor preferred term~editor preferred label: occurs in
definition: b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
alternative term: occurs_in
alternative term: unfolds in
alternative term: unfolds_in
database_cross_reference: BFO:0000066
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: occurs_in
comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant

contains process
type: ObjectProperty
editor preferred term~editor preferred label: site of
definition: [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
database_cross_reference: BFO:0000067
has_obo_namespace: uberon
id: contains_process
shorthand: contains_process
comment: Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant

anterior to
type: ObjectProperty
inverse of: posterior to
type: TransitiveProperty
definition: x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:0000096
has_exact_synonym: rostral_to
has_obo_namespace: spatial
has_obo_namespace: uberon
id: anterior_to
shorthand: anterior_to

Axiom
annotated source: anterior to
annotated property: definition
annotated target: x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:cjm

distal to
type: ObjectProperty
inverse of: proximal to
type: TransitiveProperty
definition: x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal).
database_cross_reference: BSPO:0000097
has_obo_namespace: spatial
has_obo_namespace: uberon
id: distal_to
shorthand: distal_to

Axiom
annotated source: distal to
annotated property: definition
annotated target: x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal).
database_cross_reference: BSPO:cjm

dorsal to
type: ObjectProperty
inverse of: ventral to
type: TransitiveProperty
definition: x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:0000098
has_obo_namespace: spatial
has_obo_namespace: uberon
id: dorsal_to
shorthand: dorsal_to

Axiom
annotated source: dorsal to
annotated property: definition
annotated target: x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:cjm

posterior to
type: ObjectProperty
type: TransitiveProperty
definition: x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:0000099
has_narrow_synonym: caudal to
has_obo_namespace: spatial
has_obo_namespace: uberon
id: posterior_to
shorthand: posterior_to

Axiom
annotated source: posterior to
annotated property: definition
annotated target: x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail.
database_cross_reference: BSPO:cjm

Axiom
annotated source: posterior to
annotated property: has_narrow_synonym
annotated target: caudal to
has_synonym_type: vertebrate

proximal to
type: ObjectProperty
type: TransitiveProperty
definition: x proximal to y iff x is closer to the point of attachment with the body than y.
database_cross_reference: BSPO:0000100
database_cross_reference: NCIT:C25236
has_obo_namespace: spatial
has_obo_namespace: uberon
id: proximal_to
shorthand: proximal_to
comment: The elbow is proximal to the hand, but distal to the shoulder.

Axiom
annotated source: proximal to
annotated property: definition
annotated target: x proximal to y iff x is closer to the point of attachment with the body than y.
database_cross_reference: BSPO:cjm

ventral to
type: ObjectProperty
type: TransitiveProperty
definition: x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:0000102
has_obo_namespace: spatial
has_obo_namespace: uberon
id: ventral_to
shorthand: ventral_to

Axiom
annotated source: ventral to
annotated property: definition
annotated target: x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly).
database_cross_reference: BSPO:cjm

deep to
type: ObjectProperty
inverse of: superficial to
type: TransitiveProperty
definition: Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines.
database_cross_reference: BSPO:0000107
has_obo_namespace: spatial
has_obo_namespace: uberon
id: deep_to
shorthand: deep_to

Axiom
annotated source: deep to
annotated property: definition
annotated target: Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines.
database_cross_reference: BSPO:cjm

superficial to
type: ObjectProperty
type: TransitiveProperty
definition: Near the outer surface of the organism. Thus, skin is superficial to the muscle layer.
database_cross_reference: BSPO:0000108
has_obo_namespace: spatial
has_obo_namespace: uberon
id: superficial_to
shorthand: superficial_to

Axiom
annotated source: superficial to
annotated property: definition
annotated target: Near the outer surface of the organism. Thus, skin is superficial to the muscle layer.
database_cross_reference: BSPO:cjm

in left side of
type: ObjectProperty
sub property of: in lateral side of
property disjoint with: in right side of
definition: X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion.
database_cross_reference: BSPO:0000120
database_cross_reference: NCIT:C25229
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_left_side_of
shorthand: in_left_side_of

Axiom
annotated source: in left side of
annotated property: definition
annotated target: X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion.
database_cross_reference: BSPO:PATO_mtg_2009

in right side of
type: ObjectProperty
sub property of: in lateral side of
definition: X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion.
database_cross_reference: BSPO:0000121
database_cross_reference: NCIT:C25228
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_right_side_of
shorthand: in_right_side_of

Axiom
annotated source: in right side of
annotated property: definition
annotated target: X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion.
database_cross_reference: BSPO:PATO_mtg_2009

in posterior side of
type: ObjectProperty
sub property of: part of
definition: X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion.
database_cross_reference: BSPO:0000122
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_posterior_side_of
shorthand: in_posterior_side_of

Axiom
annotated source: in posterior side of
annotated property: definition
annotated target: X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion.
database_cross_reference: BSPO:PATO_mtg_2009

in anterior side of
type: ObjectProperty
sub property of: part of
definition: X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion.
database_cross_reference: BSPO:0000123
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_anterior_side_of
shorthand: in_anterior_side_of

Axiom
annotated source: in anterior side of
annotated property: definition
annotated target: X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion.
database_cross_reference: BSPO:PATO_mtg_2009

in proximal side of
type: ObjectProperty
sub property of: part of
definition: x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion.
database_cross_reference: BSPO:0000124
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_proximal_side_of
shorthand: in_proximal_side_of

Axiom
annotated source: in proximal side of
annotated property: definition
annotated target: x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion.
database_cross_reference: BSPO:PATO_mtg_2009

in distal side of
type: ObjectProperty
sub property of: part of
definition: x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion.
database_cross_reference: BSPO:0000125
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_distal_side_of
shorthand: in_distal_side_of

Axiom
annotated source: in distal side of
annotated property: definition
annotated target: x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion.
database_cross_reference: BSPO:PATO_mtg_2009

in lateral side of
type: ObjectProperty
sub property of: part of
definition: X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure
database_cross_reference: BSPO:0000126
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_lateral_side_of
shorthand: in_lateral_side_of

Axiom
annotated source: in lateral side of
annotated property: definition
annotated target: X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure
database_cross_reference: UBERON:cjm

proximalmost part of
type: ObjectProperty
sub property of: in proximal side of
definition: X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y
database_cross_reference: BSPO:0001106
has_obo_namespace: spatial
has_obo_namespace: uberon
id: proximalmost_part_of
shorthand: proximalmost_part_of

Axiom
annotated source: proximalmost part of
annotated property: definition
annotated target: X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y
database_cross_reference: https://orcid.org/0000-0002-6601-2165

immediately deep to
type: ObjectProperty
sub property of: deep to
inverse of: immediately superficial to
definition: x immediately deep to y iff x deep_to y and x is contiguous with y.
database_cross_reference: BSPO:0001107
has_obo_namespace: spatial
has_obo_namespace: uberon
id: immediately_deep_to
shorthand: immediately_deep_to

Axiom
annotated source: immediately deep to
annotated property: definition
annotated target: x immediately deep to y iff x deep_to y and x is contiguous with y.
database_cross_reference: BSPO:curators

distalmost part of
type: ObjectProperty
sub property of: in distal side of
definition: X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y
database_cross_reference: BSPO:0001108
has_obo_namespace: spatial
has_obo_namespace: uberon
id: distalmost_part_of
shorthand: distalmost_part_of

Axiom
annotated source: distalmost part of
annotated property: definition
annotated target: X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y
database_cross_reference: https://orcid.org/0000-0002-6601-2165

intersects midsagittal plane of
type: ObjectProperty
sub property of: part of
definition: X intersects median plane of iff X crosses the midine plane of Y.
database_cross_reference: BSPO:0005001
has_obo_namespace: spatial
has_obo_namespace: uberon
id: intersects_midsagittal_plane_of
shorthand: intersects_midsagittal_plane_of

immediately superficial to
type: ObjectProperty
sub property of: superficial to
sub property of: adjacent to
definition: x immediately superficial to y iff x superficial to y and x is contiguous with y.
database_cross_reference: BSPO:0015014
has_obo_namespace: spatial
has_obo_namespace: uberon
id: immediately_superficial_to
shorthand: immediately_superficial_to

Axiom
annotated source: immediately superficial to
annotated property: definition
annotated target: x immediately superficial to y iff x superficial to y and x is contiguous with y.
database_cross_reference: BSPO:curators

in dorsal side of
type: ObjectProperty
sub property of: part of
definition: X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion.
database_cross_reference: BSPO:0015101
has_obo_namespace: spatial
has_obo_namespace: uberon
id: in_dorsal_side_of
shorthand: in_dorsal_side_of

Axiom
annotated source: in dorsal side of
annotated property: definition
annotated target: X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion.
database_cross_reference: BSPO:cjm

lacks_part
type: ObjectProperty
expand expression to: http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y

lacks_plasma_membrane_part
type: ObjectProperty
expand expression to: http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)

partially_surrounded_by
type: ObjectProperty
example of usage: A duck swimming in a pond is partially surrounded by air and partially surrounded by water.
definition: x partially_surrounded_by y if and only if (1) x is adjacent to y and for the region r that is adjacent to x, r partially overlaps y (2) the shared boundary between x and y occupies a non-trivial proportion of the outermost boundary of x
comment: Definition modified from 'surrounded by'.

derives from part of
type: ObjectProperty
definition: A relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist through the separation or transformation of a part of the old entity, and the new entity inherits a significant portion of the matter belonging to that part of the old entity.

has increased levels of
type: ObjectProperty
sub property of: has component
definition: A has part relationship between a whole and a part, where the number of parts present in the whole is higher than in comparable entities.
comment: This relation is present in ENVO to support compositional classes such as "X-enriched soil". These will later be formalized, and a different relation from RO may be chosen.

results in transformation into
type: ObjectProperty

results in expansion of
type: ObjectProperty
example of usage: Afforestation results in the expansion of a forest.
definition: A process, p, results in the expansion of a material entity, m, if the spatial extent of m is increased as a result of participating in p.

results in proliferation of
type: ObjectProperty
comment: To be ceded to RO

generates
type: ObjectProperty
definition: A relation between a process and a disposition such that the existence of the disposition is caused by the execution of the process.
editor note: Consider ceding to RO
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-11-03T20:58:13Z

results in distribution of
type: ObjectProperty
database_cross_reference: GOREL:0002003
has_obo_namespace: external
id: results_in_distribution_of
shorthand: results_in_distribution_of
label: results_in_distribution_of

results in fission of
type: ObjectProperty
sub property of: has participant
database_cross_reference: GOREL:0002004
has_obo_namespace: external
id: results_in_fission_of
shorthand: results_in_fission_of
label: results_in_fission_of

derives_by_manipulation_from
type: ObjectProperty
definition: A derives_by_manipulation_from B means: A is a type of in vitro plant structure, and every instance of A exists at a point in time later than some instance of B from which it was created through human manipulation, and every instance of A inherited a biologically significant portion of its matter from the instance of B from which it was derived.
created by: rwalls
creation date: 2010-07-01T02:45:12Z
database_cross_reference: PO:0040001
has_obo_namespace: plant_ontology
id: derives_by_manipulation_from
shorthand: derives_by_manipulation_from
comment: The derives_by_manipulation_from relation, is a special case of the RO relation derives_from. Derives_from implies an instance level derivation that holds between two distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Likewise, derives_by_manipulation_from joins two plant structures before and after some manipulation. Specifically, derives_by_manipulation_from is used to describe the relation between an in vitro plant structure and the in vivo plant structure that is its temporal precursor.

Axiom
annotated source: derives_by_manipulation_from
annotated property: definition
annotated target: A derives_by_manipulation_from B means: A is a type of in vitro plant structure, and every instance of A exists at a point in time later than some instance of B from which it was created through human manipulation, and every instance of A inherited a biologically significant portion of its matter from the instance of B from which it was derived.
database_cross_reference: POC:curators

isolated from germplasm
type: ObjectProperty
database_cross_reference: PO:0040002
has_obo_namespace: plant_ontology
id: isolated_from_germplasm
shorthand: isolated_from_germplasm

characteristic of
type: ObjectProperty
sub property of: characteristic of part of
inverse of: has characteristic
type: FunctionalProperty
editor preferred term~editor preferred label: inheres in
example of usage: this fragility is a characteristic of this vase
example of usage: this red color is a characteristic of this apple
definition: a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
alternative term: inheres_in
temporal interpretation: RO_0001901
database_cross_reference: RO:0000052
shorthand: characteristic_of
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.

has characteristic
type: ObjectProperty
type: InverseFunctionalProperty
range: characteristic
editor preferred term~editor preferred label: bearer of
example of usage: this apple is bearer of this red color
example of usage: this vase is bearer of this fragility
definition: Inverse of characteristic_of
editor note: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
alternative term: bearer_of
alternative term: is bearer of
temporal interpretation: RO_0001901
database_cross_reference: RO:0000053
shorthand: has_characteristic

participates in
type: ObjectProperty
inverse of: has participant
domain: continuant
range: occurrent
editor preferred term~editor preferred label: participates in
example of usage: this blood clot participates in this blood coagulation
example of usage: this input material (or this output material) participates in this process
example of usage: this investigator participates in this investigation
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
alternative term: participates_in
database_cross_reference: RO:0000056
has_obo_namespace: plant_ontology
has_obo_namespace: uberon
id: participates_in
shorthand: participates_in
label: participates_in

has participant
type: ObjectProperty
domain: occurrent
domain: process
range: continuant
property chain axiom: has part
property chain axiom: realizes
property chain axiom: characteristic of
editor preferred term~editor preferred label: has participant
example of usage: this blood coagulation has participant this blood clot
example of usage: this investigation has participant this investigator
example of usage: this process has participant this input material (or this output material)
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
editor note: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
alternative term: has_participant
source: http://www.obofoundry.org/ro/#OBO_REL:has_participant
database_cross_reference: RO:0000057
has_obo_namespace: plant_ontology
id: has_participant
shorthand: has_participant
label: has_participant

is concretized as
type: ObjectProperty
inverse of: concretizes
domain: generically dependent continuant
range: characteristic
example of usage: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
example of usage: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants.

concretizes
type: ObjectProperty
domain: characteristic
range: generically dependent continuant
example of usage: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
example of usage: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant.

function of
type: ObjectProperty
sub property of: characteristic of
inverse of: has function
domain: function
example of usage: this catalysis function is a function of this enzyme
definition: a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
editor note: A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists.
alternative term: function_of
alternative term: is function of
database_cross_reference: RO:0000079
shorthand: function_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

quality of
type: ObjectProperty
sub property of: characteristic of
inverse of: has quality
example of usage: this red color is a quality of this apple
definition: a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
editor note: A quality inheres in its bearer at all times for which the quality exists.
alternative term: is quality of
alternative term: quality_of
database_cross_reference: RO:0000080
shorthand: quality_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

role of
type: ObjectProperty
sub property of: characteristic of
inverse of: has role
example of usage: this investigator role is a role of this person
definition: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
editor note: A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
alternative term: is role of
alternative term: role_of
database_cross_reference: RO:0000081
shorthand: role_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has function
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: function
example of usage: this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)
definition: a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
editor note: A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists.
alternative term: has_function
database_cross_reference: RO:0000085
shorthand: has_function

has quality
type: ObjectProperty
sub property of: has characteristic
range: quality
example of usage: this apple has quality this red color
definition: a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
editor note: A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.
alternative term: has_quality
database_cross_reference: RO:0000086
has_obo_namespace: uberon
id: has_quality
shorthand: has_quality

has role
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: role
example of usage: this person has role this investigator role (more colloquially: this person has this role of investigator)
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
editor note: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
alternative term: has_role
database_cross_reference: RO:0000087
shorthand: has_role

has disposition
type: ObjectProperty
sub property of: has characteristic
inverse of: disposition of
domain: independent continuant
range: disposition
definition: a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence
database_cross_reference: RO:0000091
shorthand: has_disposition

disposition of
type: ObjectProperty
sub property of: characteristic of
definition: inverse of has disposition
database_cross_reference: RO:0000092
in_subset: defined by inverse
shorthand: disposition_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

derives from
type: ObjectProperty
sub property of: derives from part of
inverse of: derives into
example of usage: this cell derives from this parent cell (cell division)
example of usage: this nucleus derives from this parent nucleus (nuclear division)
has curation status: IAO_0000125
definition: a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
editor note: This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'.
alternative term: derives_from
curator note: This relation is taken from the RO2005 version of RO. It may be obsoleted and replaced by relations with different definitions. See also the 'develops from' family of relations.
in_subset: eco subset

derives into
type: ObjectProperty
example of usage: this parent cell derives into this cell (cell division)
example of usage: this parent nucleus derives into this nucleus (nuclear division)
has curation status: IAO_0000125
definition: a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
editor note: This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'.
alternative term: derives_into
in_subset: eco subset

location of
type: ObjectProperty
inverse of: located in
type: TransitiveProperty
editor preferred term~editor preferred label: is location of
example of usage: my head is the location of my brain
example of usage: this cage is the location of this rat
definition: a relation between two independent continuants, the location and the target, in which the target is entirely within the location
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
alternative term: location_of
temporal interpretation: RO_0001901
database_cross_reference: RO:0001015
has_obo_namespace: uberon
id: location_of
shorthand: location_of

is allergic trigger for
type: ObjectProperty
sub property of: causes or contributes to condition
inverse of: has allergic trigger
domain: material entity
example of usage: penicillin (CHEBI:17334) is allergic trigger for penicillin allergy (DOID:0060520)
definition: A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.

is autoimmune trigger for
type: ObjectProperty
sub property of: causes or contributes to condition
inverse of: has autoimmune trigger
domain: material entity
definition: A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.

has allergic trigger
type: ObjectProperty
sub property of: causes or contributes to condition
range: material entity
example of usage: penicillin allergy (DOID:0060520) has allergic trigger penicillin (CHEBI:17334)
definition: A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.

has autoimmune trigger
type: ObjectProperty
sub property of: causes or contributes to condition
range: material entity
definition: A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.

located in
type: ObjectProperty
type: TransitiveProperty
domain: independent continuant
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
range: independent continuant
range: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
property chain axiom: part of
editor preferred term~editor preferred label: located in
example of usage: my brain is located in my head
example of usage: this rat is located in this cage
definition: a relation between two independent continuants, the target and the location, in which the target is entirely within the location
editor note: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
alternative term: located_in
temporal interpretation: RO_0001901
source: http://www.obofoundry.org/ro/#OBO_REL:located_in
created by: rwalls
creation date: 2012-05-23T09:52:02Z
database_cross_reference: RO:0001025
has_obo_namespace: plant_ontology
has_obo_namespace: uberon
id: located_in
in_subset: valid_for_go_gp2term
shorthand: located_in
label: located_in

Axiom
annotated source: located in
annotated property: domain
annotated target: independent continuant
editor note: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

Axiom
annotated source: located in
annotated property: range
annotated target: independent continuant
editor note: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

2D boundary of
type: ObjectProperty
sub property of: mereotopologically related to
inverse of: has 2D boundary
example of usage: the surface of my skin is a 2D boundary of my body
definition: a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity
editor note: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
editor note: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.
alternative term: 2D_boundary_of
alternative term: boundary of
alternative term: is 2D boundary of
alternative term: is boundary of
alternative term: surface of
temporal interpretation: RO_0001901
database_cross_reference: RO:0002000
shorthand: 2D_boundary_of

aligned with
type: ObjectProperty
type: TransitiveProperty
has curation status: IAO_0000125
editor note: May be obsoleted, see https://github.com/oborel/obo-relations/issues/260
term editor: https://orcid.org/0000-0002-7073-9172
temporal interpretation: RO_0001901

has 2D boundary
type: ObjectProperty
sub property of: mereotopologically related to
domain: material entity
range: immaterial entity
example of usage: my body has 2D boundary the surface of my skin
definition: a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity
editor note: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
editor note: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.
term editor: https://orcid.org/0000-0002-7073-9172
alternative term: has boundary
alternative term: has_2D_boundary
temporal interpretation: RO_0001901
database_cross_reference: RO:0002002
has_obo_namespace: uberon
id: has_boundary
shorthand: has_2D_boundary
shorthand: has_boundary

electrically_synapsed_to
type: ObjectProperty
sub property of: connected to
definition: A relation that holds between two neurons that are electrically coupled via gap junctions.
term editor: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

tracheates
type: ObjectProperty
sub property of: located in
domain: UBERON_0000061
range: UBERON_0000061
definition: The relationship that holds between a trachea or tracheole and an antomical structure that is contained in (and so provides an oxygen supply to).
term editor: https://orcid.org/0000-0002-7073-9172

innervated_by
type: ObjectProperty
inverse of: innervates
domain: UBERON_0000061
range: UBERON_0000122
property chain axiom: branching part of
term editor: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
database_cross_reference: RO:0002005
has_obo_namespace: uberon
id: innervated_by
shorthand: innervated_by

has synaptic terminal of
type: ObjectProperty
sub property of: overlaps
inverse of: has synaptic terminal in
term editor: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

bounding layer of
type: ObjectProperty
sub property of: part of
domain: Class
  intersection of: material entity
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002124
range: material entity
definition: X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000
term editor: https://orcid.org/0000-0002-7073-9172
term editor: David Osumi-Sutherland
database_cross_reference: RO:0002007
has_obo_namespace: uberon
id: bounding_layer_of
in_subset: eco subset
shorthand: bounding_layer_of
comment: A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane.

coincident with
type: ObjectProperty
sub property of: mereotopologically related to
domain: Class
  intersection of: continuant
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001199
range: Class
  intersection of: continuant
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001199
definition: A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other.
editor note: Note from NCEAS meeting: consider changing primary label
term editor: https://orcid.org/0000-0002-7073-9172
term editor: David Osumi-Sutherland
in_subset: eco subset
comment: Example: if we define region of chromosome as any subdivision of a chromosome along its long axis, then we can define a region of chromosome that contains only gene x as 'chromosome region' that coincident_with some 'gene x', where the term gene X corresponds to a genomic sequence.

cell expresses
type: ObjectProperty
sub property of: expresses
domain: cell
definition: A relation that applies between a cell(c) and a gene(g) , where the process of 'transcription, DNA templated (GO_0006351)' is occuring in in cell c and that process has input gene g.
term editor: https://orcid.org/0000-0002-7073-9172
description: x 'cell expresses' y iff: cell(x) AND gene(y) AND exists some 'transcription, DNA templated (GO_0006351)'(t) AND t occurs_in x AND t has_input y

regulates in another organism
type: ObjectProperty
sub property of: causally upstream of or within
domain: process
range: process
definition: x 'regulates in other organism' y if and only if: (x is the realization of a function to exert an effect on the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).
term editor: https://orcid.org/0000-0002-7073-9172
has_exact_synonym: regulates in other organism
in_subset: valid_for_go_ontology

regulates transport of
type: ObjectProperty
property chain axiom: regulates (processual)
property chain axiom: transports or maintains localization of
definition: A relationship that holds between a process that regulates a transport process and the entity transported by that process.
term editor: https://orcid.org/0000-0002-7073-9172
in_subset: eco subset

occurrent part of
type: ObjectProperty
sub property of: part of
sub property of: causally upstream of or within
domain: occurrent
range: occurrent
definition: A part of relation that applies only between occurrents.

has regulatory component activity
type: ObjectProperty
sub property of: has component activity
sub property of: regulated by
definition: A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-05-24T09:30:46Z
database_cross_reference: RO:0002013
shorthand: has_regulatory_component_activity

has negative regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: negatively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-05-24T09:31:01Z
database_cross_reference: RO:0002014
shorthand: has_negative_regulatory_component_activity
comment: By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.

has positive regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: positively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-05-24T09:31:17Z
database_cross_reference: RO:0002015
shorthand: has_positive_regulatory_component_activity
comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.

has necessary component activity
type: ObjectProperty
sub property of: has component activity
sub property of: positively regulated by
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-05-24T09:36:08Z
comment: A has necessary component activity B if A and B are GO molecular functions (GO_0003674), A has_component B and B is necessary for A. For example, ATPase coupled transporter activity has necessary component ATPase activity; transcript factor activity has necessary component DNA binding activity.

has component activity
type: ObjectProperty
sub property of: has component process
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-05-24T09:44:33Z
database_cross_reference: RO:0002017
shorthand: has_component_activity
comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.

has component process
type: ObjectProperty
sub property of: has component
domain: process
range: process
definition: w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-05-24T09:49:21Z
database_cross_reference: RO:0002018
shorthand: has_component_process

has ligand
type: ObjectProperty
sub property of: has input
definition: A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-07-19T17:30:36Z

transports
type: ObjectProperty
sub property of: transports or maintains localization of
definition: Holds between p and c when p is a transport process or transporter activity and the outcome of this p is to move c from one location to another.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-07-20T17:11:08Z

occurs across
type: ObjectProperty
sub property of: has part that occurs in
definition: A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-07-20T17:19:37Z
database_cross_reference: RO:0002021
shorthand: occurs_across

directly regulated by
type: ObjectProperty
sub property of: regulated by
inverse of: directly regulates
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-09-17T13:52:24Z
database_cross_reference: RO:0002022
shorthand: directly_regulated_by
comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.

Axiom
annotated source: directly regulated by
annotated property: comment
annotated target: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: directly regulated by
annotated property: comment
annotated target: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
database_cross_reference: GOC:dos

directly negatively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly negatively regulates
definition: Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-09-17T13:52:38Z
database_cross_reference: RO:0002023
shorthand: directly_negatively_regulated_by

Axiom
annotated source: directly negatively regulated by
annotated property: definition
annotated target: Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: directly negatively regulated by
annotated property: definition
annotated target: Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
database_cross_reference: GOC:dos

directly positively regulated by
type: ObjectProperty
sub property of: directly regulated by
inverse of: directly positively regulates
definition: Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-09-17T13:52:47Z
database_cross_reference: RO:0002024
shorthand: directly_positively_regulated_by

Axiom
annotated source: directly positively regulated by
annotated property: definition
annotated target: Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: directly positively regulated by
annotated property: definition
annotated target: Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
database_cross_reference: GOC:dos

has effector activity
type: ObjectProperty
sub property of: has component activity
type: FunctionalProperty
definition: A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
created by: https://orcid.org/0000-0002-7073-9172
created by: dos
creation date: 2017-09-22T14:14:36Z
database_cross_reference: RO:0002025
shorthand: has_effector_activity
comment: This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.

Axiom
annotated source: has effector activity
annotated property: definition
annotated target: A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: has effector activity
annotated property: definition
annotated target: A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
database_cross_reference: GOC:dos

in register with
type: ObjectProperty
sub property of: mereotopologically related to
domain: image
range: image
definition: A relationship that holds between two images, A and B, where: A depicts X; B depicts Y; X and Y are both of type T' C is a 2 layer image consiting of layers A and B; A and B are aligned in C according to a shared co-ordinate framework so that common features of X and Y are co-incident with each other. Note: A and B may be 2D or 3D. Examples include: the relationship between two channels collected simultaneously from a confocal microscope; the relationship between an image dpeicting X and a painted annotation layer that delineates regions of X; the relationship between the tracing of a neuron on an EM stack and the co-ordinate space of the stack; the relationship between two separately collected images that have been brought into register via some image registration software.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2017-12-07T12:58:06Z

Axiom
annotated source: in register with
annotated property: definition
annotated target: A relationship that holds between two images, A and B, where: A depicts X; B depicts Y; X and Y are both of type T' C is a 2 layer image consiting of layers A and B; A and B are aligned in C according to a shared co-ordinate framework so that common features of X and Y are co-incident with each other. Note: A and B may be 2D or 3D. Examples include: the relationship between two channels collected simultaneously from a confocal microscope; the relationship between an image dpeicting X and a painted annotation layer that delineates regions of X; the relationship between the tracing of a neuron on an EM stack and the co-ordinate space of the stack; the relationship between two separately collected images that have been brought into register via some image registration software.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

before or simultaneous with
type: ObjectProperty
sub property of: temporally related to
term editor: David Osumi-Sutherland
alternative term: <=
database_cross_reference: RO:0002081
in_subset: eco subset
shorthand: before_or_simultaneous_with
comment: Primitive instance level timing relation between events

simultaneous with
type: ObjectProperty
sub property of: before or simultaneous with
type: SymmetricProperty
type: TransitiveProperty
definition: x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time.
term editor: https://orcid.org/0000-0002-7073-9172
term editor: David Osumi-Sutherland
database_cross_reference: RO:0002082
has_obo_namespace: uberon
id: simultaneous_with
in_subset: eco subset
shorthand: simultaneous_with
comment: t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2)

before
type: ObjectProperty
sub property of: before or simultaneous with
type: TransitiveProperty
term editor: David Osumi-Sutherland
in_subset: eco subset
comment: t1 before t2 iff:= t1 before_or_simulataneous_with t2 and not (t1 simultaeous_with t2)

during which ends
type: ObjectProperty
sub property of: temporally related to
inverse of: ends during
term editor: David Osumi-Sutherland
in_subset: eco subset
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

encompasses
type: ObjectProperty
sub property of: during which starts
inverse of: happens during
type: TransitiveProperty
term editor: https://orcid.org/0000-0002-7073-9172
term editor: David Osumi-Sutherland
alternative term: di
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

ends after
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
property chain axiom: ends during
property chain axiom: preceded by
term editor: David Osumi-Sutherland
database_cross_reference: RO:0002086
in_subset: eco subset
shorthand: ends_after
comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)

immediately preceded by
type: ObjectProperty
sub property of: preceded by
inverse of: immediately precedes
property chain axiom: starts with
property chain axiom: ends with
term editor: David Osumi-Sutherland
alternative term: starts_at_end_of
database_cross_reference: RO:0002087
has_obo_namespace: uberon
id: immediately_preceded_by
shorthand: immediately_preceded_by
comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)

during which starts
type: ObjectProperty
sub property of: temporally related to
inverse of: starts during
term editor: David Osumi-Sutherland
in_subset: eco subset
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

starts before
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
term editor: David Osumi-Sutherland
in_subset: eco subset

immediately precedes
type: ObjectProperty
sub property of: precedes
property chain axiom: ends with
property chain axiom: starts with
term editor: https://orcid.org/0000-0002-7073-9172
term editor: David Osumi-Sutherland
alternative term: ends_at_start_of
alternative term: meets
is direct form of: precedes
database_cross_reference: RO:0002090
in_subset: eco subset
shorthand: immediately_precedes
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)

starts during
type: ObjectProperty
sub property of: temporally related to
domain: occurrent
range: occurrent
term editor: David Osumi-Sutherland
alternative term: io
in_subset: eco subset
comment: X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))

happens during
type: ObjectProperty
sub property of: starts during
sub property of: ends during
type: TransitiveProperty
term editor: David Osumi-Sutherland
alternative term: d
alternative term: during
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
in_subset: eco subset
comment: X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))

ends during
type: ObjectProperty
sub property of: temporally related to
term editor: David Osumi-Sutherland
alternative term: o
alternative term: overlaps
in_subset: eco subset
comment: X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y).

has soma location
type: ObjectProperty
sub property of: overlaps
domain: CL_0000540
range: UBERON_0000465
property chain axiom: part of
has curation status: IAO_0000125
definition: Relation between a neuron and a material anatomical entity that its soma is part of.
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0043025> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)
temporal interpretation: RO_0001901
database_cross_reference: RO:0002100
shorthand: has_soma_location

fasciculates with
type: ObjectProperty
sub property of: overlaps
inverse of: has fasciculating neuron projection
domain: CL_0000540
range: UBERON_0000122
has curation status: IAO_0000125
definition: relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.
term editor: https://orcid.org/0000-0002-7073-9172
alternative term: fasciculates with
first order logic expression: (forall (?x ?y) (iff (fasciculates_with ?x ?y) (exists (?nps ?npbs) (and ("neuron ; CL_0000540" ?x) ("neuron projection bundle ; CARO_0001001" ?y) ("neuron projection segment ; CARO_0001502" ?nps) ("neuron projection bundle segment ; CARO_0001500' " ?npbs) (part_of ?npbs ?y) (part_of ?nps ?x) (part_of ?nps ?npbs) (forall (?npbss) (if (and ("neuron projection bundle subsegment ; CARO_0001501" ?npbss) (part_of ?npbss ?npbs) ) (overlaps ?nps ?npbss) ))))))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

axon synapses in
type: ObjectProperty
sub property of: has presynaptic terminal in
domain: CL_0000540
property chain axiom: part of
has curation status: IAO_0000125
definition: Relation between a neuron and some structure its axon forms (chemical) synapses in.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0030424> and <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0042734> and <http://purl.obolibrary.org/obo/BFO_0000050> some ( <http://purl.obolibrary.org/obo/GO_0045202> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

synapsed by
type: ObjectProperty
sub property of: receives input from
inverse of: synapsed to
range: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
has curation status: IAO_0000125
definition: Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that has_part some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
database_cross_reference: RO:0002103
has_obo_namespace: uberon
id: synapsed_by
shorthand: synapsed_by

has plasma membrane part
type: ObjectProperty
sub property of: has part
domain: UBERON_0000465
range: UBERON_0000465
example of usage: Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]
has curation status: IAO_0000125
definition: Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.
term editor: https://orcid.org/0000-0001-9990-8331
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0003-1617-8244
definition source: http://www.ncbi.nlm.nih.gov/pubmed/19243617
expand expression to: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0005886> and <http://purl.obolibrary.org/obo/BFO_0000051> some ?Y)
temporal interpretation: RO_0001901
database_cross_reference: RO:0002104
shorthand: has_plasma_membrane_part

synapsed_via_type_Ib_bouton_to
type: ObjectProperty
sub property of: synapsed to
inverse of: synapsed_by_via_type_Ib_bouton
has curation status: IAO_0000125
definition: A relation between a motor neuron and a muscle that it synapses to via a type Ib bouton.
term editor: https://orcid.org/0000-0001-5948-3092
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: BFO_0000051 some (GO_0061176 that BFO_0000051 some (that BFO_0000051 some (GO_0045202 that BFO_0000051 some ( that BFO_0000050 some ?Y))))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: Expands to: has_part some ('type Ib terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

synapsed_via_type_Is_bouton_to
type: ObjectProperty
sub property of: synapsed to
inverse of: synapsed_by_via_type_Is_bouton
has curation status: IAO_0000125
definition: A relation between a motor neuron and a muscle that it synapses to via a type Is bouton.
term editor: https://orcid.org/0000-0001-5948-3092
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: BFO_0000051 some (GO_0061177 that BFO_0000051 some (that BFO_0000051 some (GO_0045202 that BFO_0000051 some ( that BFO_0000050 some ?Y))))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: Expands to: has_part some ('type Is terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

synapsed_via_type_II_bouton_to
type: ObjectProperty
sub property of: synapsed to
inverse of: synapsed_by_via_type_II_bouton
has curation status: IAO_0000125
definition: A relation between a motor neuron and a muscle that it synapses to via a type II bouton.
term editor: https://orcid.org/0000-0001-5948-3092
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: BFO_0000051 some (GO_0061175 that BFO_0000051 some (that BFO_0000051 some (GO_0045202 that BFO_0000051 some ( that BFO_0000050 some ?Y))))
temporal interpretation: RO_0001901
comment: Expands to: has_part some ('type II terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

synapsed_by_via_type_II_bouton
type: ObjectProperty
sub property of: synapsed by
has curation status: IAO_0000125
definition: Relation between a muscle and a motor neuron that synapses to it via a type II bouton.
term editor: https://orcid.org/0000-0001-5948-3092
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061174 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type II terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

synapsed_by_via_type_Ib_bouton
type: ObjectProperty
sub property of: synapsed by
has curation status: IAO_0000125
definition: Relation between a muscle and a motor neuron that synapses to it via a type Ib bouton.
term editor: https://orcid.org/0000-0001-5948-3092
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061176 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Ib terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

has postsynaptic terminal in
type: ObjectProperty
sub property of: has synaptic terminal in
inverse of: has presynaptic terminal in
domain: CL_0000540
property chain axiom: part of
has curation status: IAO_0000125
definition: Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
alternative term: synapsed in
expand expression to: http://purl.obolibrary.org/obo/BFO_0000051 some ( http://purl.org/obo/owl/GO#GO_0045211 and http://purl.obolibrary.org/obo/BFO_0000050 some ( http://purl.org/obo/owl/GO#GO_0045202 and http://purl.obolibrary.org/obo/BFO_0000050 some ?Y))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

releases neurotransmitter
type: ObjectProperty
domain: UBERON_0000061
range: material entity
has curation status: IAO_0000125
alternative term: has neurotransmitter

synapsed_by_via_type_Is_bouton
type: ObjectProperty
sub property of: synapsed by
has curation status: IAO_0000125
definition: Relation between a muscle and a motor neuron that synapses to it via a type Is bouton.
term editor: https://orcid.org/0000-0001-5948-3092
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061177 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Is terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

has presynaptic terminal in
type: ObjectProperty
sub property of: has synaptic terminal in
domain: CL_0000540
property chain axiom: part of
has curation status: IAO_0000125
definition: Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.
alternative term: synapses in
expand expression to: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

synapsed_via_type_III_bouton_to
type: ObjectProperty
sub property of: synapsed to
inverse of: synapsed_by_via_type_III_bouton
definition: A relation between a motor neuron and a muscle that it synapses to via a type III bouton.
expand expression to: BFO_0000051 some (GO_0061177 that BFO_0000051 some (that BFO_0000051 some (GO_0097467 that BFO_0000051 some ( that BFO_0000050 some ?Y))))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: Expands to: has_part some ('type III terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

synapsed_by_via_type_III_bouton
type: ObjectProperty
sub property of: synapsed by
definition: Relation between a muscle and a motor neuron that synapses to it via a type III bouton.
expand expression to: BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0097467 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type III terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

synapsed to
type: ObjectProperty
sub property of: sends output to
domain: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
has curation status: IAO_0000125
definition: Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
database_cross_reference: RO:0002120
shorthand: synapsed_to
comment: N1 synapsed_to some N2 Expands to: N1 SubclassOf ( has_part some ( ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( ‘synapse ; GO:0045202’ that has_part some ( ‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))

dendrite synapsed in
type: ObjectProperty
sub property of: has postsynaptic terminal in
domain: CL_0000540
property chain axiom: part of
has curation status: IAO_0000125
definition: Relation between a neuron and some structure (e.g.- a brain region) in which its dendrite receives synaptic input.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0030425> and <http://purl.obolibrary.org/obo/BFO_0000051> some ( http://purl.obolibrary.org/obo/GO_0042734 and <http://purl.obolibrary.org/obo/BFO_0000050> some ( <http://purl.obolibrary.org/obo/GO_0045202> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

has synaptic terminal in
type: ObjectProperty
sub property of: overlaps
domain: CL_0000540
property chain axiom: part of
has curation status: IAO_0000125
definition: A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input.
term editor: https://orcid.org/0000-0002-7073-9172
alternative term: has synapse in
expand expression to: <http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

overlaps
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
property chain axiom: part of
property chain axiom: has part
has curation status: IAO_0000125
definition: x overlaps y if and only if there exists some z such that x has part z and z part of y
definition: x overlaps y iff they have some part in common.
expand expression to: http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
temporal interpretation: RO_0001901
database_cross_reference: RO:0002131
has_obo_namespace: spatial
has_obo_namespace: uberon
id: overlaps
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_gocam
in_subset: eco subset
shorthand: overlaps
comment: "(forall (x y) (iff (overlaps x y) (exists (z) (and (part of z x) (part of z y)))))" CLIF []

Axiom
annotated source: overlaps
annotated property: propertyChainAxiom
annotated target: has part
annotated target: part of
RO_0002582: true

Axiom
annotated source: overlaps
annotated property: definition
annotated target: x overlaps y iff they have some part in common.
database_cross_reference: BSPO:cjm

has fasciculating neuron projection
type: ObjectProperty
sub property of: overlaps
domain: UBERON_0000122
range: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
has curation status: IAO_0000125
definition: The relation between a neuron projection bundle and a neuron projection that is fasciculated with it.
term editor: https://orcid.org/0000-0002-7073-9172
alternative term: has fasciculating component
first order logic expression: (forall (?x ?y) (iff (has_fasciculating_neuron_projection ?x ?y) (exists (?nps ?npbs) (and ("neuron projection bundle ; CARO_0001001" ?x) ("neuron projection ; GO0043005" ?y) ("neuron projection segment ; CARO_0001502" ?nps) ("neuron projection bundle segment ; CARO_0001500" ?npbs) (part_of ?nps ?y) (part_of ?npbs ?x) (part_of ?nps ?npbs) (forall (?npbss) (if (and ("neuron projection bundle subsegment ; CARO_0001501" ?npbss) (part_of ?npbss ?npbs) ) (overlaps ?nps ?npbss) ))))))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

innervates
type: ObjectProperty
domain: UBERON_0000122
property chain axiom: part of
has curation status: IAO_0000125
definition: Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.
term editor: https://orcid.org/0000-0002-7073-9172
expand expression to: <http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
temporal interpretation: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
database_cross_reference: RO:0002134
has_obo_namespace: uberon
id: innervates
shorthand: innervates

continuous with
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
domain: independent continuant
range: independent continuant
has curation status: IAO_0000125
definition: X continuous_with Y if and only if X and Y share a fiat boundary.
term editor: https://orcid.org/0000-0002-7073-9172
term editor: David Osumi-Sutherland
alternative term: connected to
curator note: The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)
temporal interpretation: RO_0001901
database_cross_reference: RO:0002150
has_obo_namespace: uberon
id: continuous_with
shorthand: continuous_with

partially overlaps
type: ObjectProperty
sub property of: overlaps
has curation status: IAO_0000125
definition: x partially overlaps y iff there exists some z such that z is part of x and z is part of y, and it is also the case that neither x is part of y or y is part of x
editor note: We would like to include disjointness axioms with part_of and has_part, however this is not possible in OWL2 as these are non-simple properties and hence cannot appear in a disjointness axiom
alternative term: proper overlaps
first order logic expression: (forall (?x ?y) (iff (proper_overlaps ?x ?y) (and (overlaps ?x ?y) (not (part_of ?x ?y)) (not (part_of ?y ?x)))))
temporal interpretation: RO_0001901
in_subset: eco subset

derived by descent from
type: ObjectProperty
sub property of: evolutionarily related to
inverse of: has derived by descendant
type: TransitiveProperty
has curation status: IAO_0000125
definition: d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a.
alternative term: ancestral_stucture_of
alternative term: evolutionarily_descended_from

has derived by descendant
type: ObjectProperty
sub property of: evolutionarily related to
type: TransitiveProperty
has curation status: IAO_0000125
definition: inverse of derived by descent from
in_subset: defined by inverse

shares ancestor with
type: ObjectProperty
sub property of: evolutionarily related to
type: SymmetricProperty
type: TransitiveProperty
property chain axiom: derived by descent from
property chain axiom: has derived by descendant
has curation status: IAO_0000125
definition: two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a.
curator note: Consider obsoleting and merging with child relation, 'in homology relationship with'
comment: VBO calls this homologous_to

serially homologous to
type: ObjectProperty
sub property of: evolutionarily related to
type: SymmetricProperty
type: TransitiveProperty
has curation status: IAO_0000125

only in taxon
type: ObjectProperty
sub property of: in taxon
example of usage: lactation SubClassOf 'only in taxon' some 'Mammalia'
has curation status: IAO_0000125
definition: x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.
editor note: The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g. 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/17921072
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20973947
database_cross_reference: RO:0002160
has_obo_namespace: plant_ontology
has_obo_namespace: uberon
id: only_in_taxon
shorthand: only_in_taxon
label: only_in_taxon

in taxon
type: ObjectProperty
sub property of: evolutionarily related to
range: OBI_0100026
property chain axiom: part of
property chain axiom: has part
property chain axiom: innervated_by
property chain axiom: overlaps
property chain axiom: continuous with
property chain axiom: connected to
property chain axiom: connects
property chain axiom: supplies
property chain axiom: develops from
property chain axiom: expressed in
property chain axiom: has prototype
property chain axiom: capable of
property chain axiom: develops from part of
property chain axiom: has developmental contribution from
property chain axiom: developmentally induced by
property chain axiom: results in developmental progression of
property chain axiom: attached to
property chain axiom: has potential to develop into
property chain axiom: existence starts during
property chain axiom: existence ends during
property chain axiom: produces
property chain axiom: produced by
property chain axiom: extends_fibers_into
has curation status: IAO_0000125
definition: x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.
term editor: 0000-0001-9227-417X
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
term editor: Jennifer Deegan
definition source: http://www.ncbi.nlm.nih.gov/pubmed/17921072
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20973947
database_cross_reference: RO:0002162
has_obo_namespace: uberon
id: in_taxon
in_subset: eco subset
shorthand: in_taxon
comment: Connects a biological entity to its taxon of origin.

spatially disjoint from
type: ObjectProperty
sub property of: mereotopologically related to
has curation status: IAO_0000125
definition: A is spatially_disjoint_from B if and only if they have no parts in common
editor note: There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
curator note: Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy
expand expression to: BFO_0000051 exactly 0 (BFO_0000050 some ?Y)
temporal interpretation: RO_0001901
database_cross_reference: RO:0002163
in_subset: eco subset
shorthand: spatially_disjoint_from

connected to
type: ObjectProperty
sub property of: mereotopologically related to
domain: Restriction
  on property: part of
  some values from: RO_0002577
range: Restriction
  on property: part of
  some values from: RO_0002577
property chain axiom:
  inverse of: connects
property chain axiom: connects
example of usage: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
database_cross_reference: RO:0002170
has_obo_namespace: uberon
id: connected_to
shorthand: connected_to

connects
type: ObjectProperty
sub property of: mereotopologically related to
domain: independent continuant
range: Restriction
  on property: part of
  some values from: RO_0002577
example of usage: The M8 connects Glasgow and Edinburgh
example of usage: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system.
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
database_cross_reference: RO:0002176
has_obo_namespace: uberon
id: connects
shorthand: connects

attached to part of
type: ObjectProperty
sub property of: mereotopologically related to
sub property of: biomechanically related to
domain: UBERON_0000061
range: UBERON_0000061
property chain axiom: attached to
property chain axiom: part of
definition: a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.
OBO foundry unique label: attached to part of (anatomical structure to anatomical structure)
database_cross_reference: RO:0002177
has_obo_namespace: uberon
id: attaches_to_part_of
shorthand: attached_to_part_of
shorthand: attaches_to_part_of

Axiom
annotated source: attached to part of
annotated property: propertyChainAxiom
annotated target: attached to
annotated target: part of
RO_0002582: true

supplies
type: ObjectProperty
sub property of: connected to
domain: UBERON_0001637
definition: Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy.
editor note: Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20064205
database_cross_reference: RO:0002178
has_obo_namespace: uberon
id: supplies
shorthand: supplies

drains
type: ObjectProperty
sub property of: connected to
domain: UBERON_0001638
definition: Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure.
editor note: Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20064205
database_cross_reference: RO:0002179
has_obo_namespace: uberon
id: drains
shorthand: drains

has component
type: ObjectProperty
sub property of: has part
has curation status: IAO_0000125
definition: w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
editor note: The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.
curator note: For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.
temporal interpretation: RO_0001901
database_cross_reference: RO:0002180
has_obo_namespace: uberon
id: has_component
in_subset: eco subset
shorthand: has_component

has phenotype
type: ObjectProperty
sub property of: has phenotype or disease
inverse of: phenotype of
domain: Class
  union of: generically dependent continuant
  union of: OGMS_0000031
  union of: UBERON_0000465
range: UPHENO_0001001
has curation status: IAO_0000125
definition: A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype).
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

phenotype of
type: ObjectProperty
type: FunctionalProperty
has curation status: IAO_0000125
definition: inverse of has phenotype
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: defined by inverse
in_subset: eco subset

develops from
type: ObjectProperty
sub property of: has developmental contribution from
sub property of: developmentally_preceded_by
inverse of: develops into
type: TransitiveProperty
domain: independent continuant
range: independent continuant
has curation status: IAO_0000125
definition: x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
term editor: https://orcid.org/0000-0001-9114-8737
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
term editor: https://orcid.org/0000-0003-1980-3228
term editor: Chris Mungall
term editor: David Osumi-Sutherland
term editor: Melissa Haendel
term editor: Terry Meehan
database_cross_reference: RO:0002202
has_obo_namespace: plant_ontology
has_obo_namespace: uberon
id: develops_from
shorthand: develops_from
comment: This is the transitive form of the develops from relation
label: develops_from

develops into
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to develop into
sub property of: has potential to directly develop into
type: TransitiveProperty
has curation status: IAO_0000125
definition: inverse of develops from
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
term editor: https://orcid.org/0000-0003-1980-3228
term editor: Chris Mungall
term editor: David Osumi-Sutherland
term editor: Terry Meehan
database_cross_reference: RO:0002203
has_obo_namespace: uberon
id: develops_into
in_subset: defined by inverse
shorthand: develops_into

gene product of
type: ObjectProperty
sub property of: genomically related to
inverse of: has gene product
domain: independent continuant
domain: Class
  union of: generically dependent continuant
  union of: material entity
range: continuant
range: Class
  union of: generically dependent continuant
  union of: material entity
property chain axiom: ribosomal translation of
property chain axiom: transcribed from
has curation status: IAO_0000125
definition: definition "x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x"
editor note: We would like to be able to express the rule: if t transcribed from g, and t is a noncoding RNA and has an evolved function, then t has gene product g.
term editor: https://orcid.org/0000-0002-6601-2165

has gene product
type: ObjectProperty
sub property of: genomically related to
domain: continuant
range: independent continuant
property chain axiom: transcribed to
property chain axiom: ribosomally translates to
example of usage: every HOTAIR lncRNA is the gene product of some HOXC gene
example of usage: every sonic hedgehog protein (PR:000014841) is the gene product of some sonic hedgehog gene
has curation status: IAO_0000125
definition: x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y
term editor: https://orcid.org/0000-0002-6601-2165

expressed in
type: ObjectProperty
sub property of: genomically related to
inverse of: expresses
domain: continuant
domain: Class
  union of: generically dependent continuant
  union of: material entity
range: UBERON_0000465
property chain axiom: part of
example of usage: 'neural crest cell' SubClassOf expresses some 'Wnt1 gene'
has curation status: IAO_0000125
definition: x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process
term editor: https://orcid.org/0000-0002-6601-2165

directly develops from
type: ObjectProperty
sub property of: develops from
inverse of: directly develops into
domain: Class
  union of: cell
  union of: UBERON_0010000
range: Class
  union of: cell
  union of: UBERON_0010000
has curation status: IAO_0000125
definition: Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
term editor: Chris Mungall
term editor: David Osumi-Sutherland
term editor: has developmental precursor
definition source: FBbt
is direct form of: develops from
database_cross_reference: RO:0002207
has_exact_synonym: has developmental precursor
has_obo_namespace: uberon
id: directly_develops_from
shorthand: directly_develops_from
comment: TODO - add child relations from DOS

parasitoid of
type: ObjectProperty
sub property of: parasite of
inverse of: has parasitoid
definition: A parasite that kills or sterilizes its host

has parasitoid
type: ObjectProperty
sub property of: parasitized by
definition: inverse of parasitoid of
in_subset: defined by inverse

directly develops into
type: ObjectProperty
sub property of: develops into
has curation status: IAO_0000125
definition: inverse of directly develops from
alternative term: developmental precursor of
database_cross_reference: RO:0002210
in_subset: defined by inverse
shorthand: directly_develops_into

regulates (processual)
type: ObjectProperty
sub property of: causally upstream of
inverse of: regulated by
type: TransitiveProperty
domain: process
range: process
property chain axiom: has effector activity
property chain axiom: ends with
property chain axiom: directly regulates
definition: p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
term editor: https://orcid.org/0000-0001-7476-6306
term editor: https://orcid.org/0000-0002-3837-8864
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
term editor: David Hill
term editor: Tanya Berardini
definition source: causal-relations
definition source: GO
curator note: Regulation precludes parthood; the regulatory process may not be within the regulated process.
OBO foundry unique label: regulates (processual)
elucidation: false
database_cross_reference: RO:0002211
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: regulates
label: regulates

negatively regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: causally upstream of, negative effect
inverse of: negatively regulated by
property chain axiom: ends with
definition: p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
OBO foundry unique label: negatively regulates (process to process)
is negative form of: regulates (processual)
database_cross_reference: RO:0002212
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: negatively_regulates

positively regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: causally upstream of, positive effect
inverse of: positively regulated by
type: TransitiveProperty
property chain axiom: negatively regulates
property chain axiom: ends with
definition: p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
OBO foundry unique label: positively regulates (process to process)
is positive form of: regulates (processual)
database_cross_reference: RO:0002213
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: positively_regulates

has prototype
type: ObjectProperty
domain: Class
  union of: independent continuant
  union of: process
example of usage: 'human p53 protein' SubClassOf some ('has prototype' some ('participates in' some 'DNA repair'))
example of usage: heart SubClassOf 'has prototype' some ('participates in' some 'blood circulation')
has curation status: IAO_0000125
definition: x has prototype y if and only if x is an instance of C and y is a prototypical instance of C. For example, every instance of heart, both normal and abnormal is related by the has prototype relation to some instance of a "canonical" heart, which participates in blood circulation.
editor note: Experimental. In future there may be a formalization in which this relation is treated as a shortcut to some modal logic axiom. We may decide to obsolete this and adopt a more specific evolutionary relationship (e.g. evolved from)
editor note: TODO: add homeomorphy axiom
editor note: This property can be used to make weaker forms of certain relations by chaining an additional property. For example, we may say: retina SubClassOf has_prototype some 'detection of light'. i.e. every retina is related to a prototypical retina instance which is detecting some light. Note that this is very similar to 'capable of', but this relation affords a wider flexibility. E.g. we can make a relation between continuants.
term editor: https://orcid.org/0000-0002-6601-2165

capable of
type: ObjectProperty
sub property of: capable of part of
domain: independent continuant
range: process
example of usage: mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
example of usage: osteoclast SubClassOf 'capable of' some 'bone resorption'
definition: A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: has function realized in
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20123131
definition source: http://www.ncbi.nlm.nih.gov/pubmed/21208450
curator note: For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".
database_cross_reference: RO:0002215
has_obo_namespace: uberon
id: capable_of
in_subset: eco subset
shorthand: capable_of

capable of part of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: part of
definition: c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: has function in
database_cross_reference: RO:0002216
has_obo_namespace: uberon
id: capable_of_part_of
shorthand: capable_of_part_of

Axiom
annotated source: capable of part of
annotated property: propertyChainAxiom
annotated target: capable of
annotated target: part of
RO_0002582: true

surrounded by
type: ObjectProperty
sub property of: adjacent to
inverse of: surrounds
has curation status: IAO_0000125
definition: x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
temporal interpretation: RO_0001901
database_cross_reference: RO:0002219
has_obo_namespace: uberon
id: surrounded_by
shorthand: surrounded_by

adjacent to
type: ObjectProperty
sub property of: spatially disjoint from
type: SymmetricProperty
domain: independent continuant
range: independent continuant
example of usage: A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.
example of usage: The epidermis layer of a vertebrate is adjacent to the dermis.
example of usage: The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies.
example of usage: The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used.
has curation status: IAO_0000125
definition: x adjacent to y if and only if x and y share a boundary.
editor note: This relation acts as a join point with BSPO
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
temporal interpretation: RO_0001901
database_cross_reference: RO:0002220
has_obo_namespace: plant_ontology
has_obo_namespace: spatial
has_obo_namespace: uberon
id: adjacent_to
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: adjacent_to
label: adjacent_to

Axiom
annotated source: adjacent to
annotated property: example of usage
annotated target: A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.

surrounds
type: ObjectProperty
sub property of: adjacent to
has curation status: IAO_0000125
definition: inverse of surrounded by
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
temporal interpretation: RO_0001901
database_cross_reference: RO:0002221
has_obo_namespace: uberon
id: surrounds
in_subset: defined by inverse
shorthand: surrounds

temporally related to
type: ObjectProperty
domain: occurrent
range: occurrent
has curation status: IAO_0000125
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: Allen's interval algebra
curator note: Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
source: https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit
database_cross_reference: RO:0002222
in_subset: eco subset
shorthand: temporally_related_to
comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.

starts
type: ObjectProperty
sub property of: part of
sub property of: temporally related to
inverse of: starts with
has curation status: IAO_0000125
definition: inverse of starts with
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: Allen
database_cross_reference: RO:0002223
has_obo_namespace: uberon
id: starts
in_subset: eco subset
shorthand: starts

starts with
type: ObjectProperty
sub property of: has part
sub property of: temporally related to
type: TransitiveProperty
example of usage: Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor
has curation status: IAO_0000125
definition: x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: started by
database_cross_reference: RO:0002224
has_obo_namespace: uberon
id: starts_with
in_subset: eco subset
shorthand: starts_with

develops from part of
type: ObjectProperty
sub property of: develops from
property chain axiom: directly develops from
property chain axiom: part of
has curation status: IAO_0000125
definition: x develops from part of y if and only if there exists some z such that x develops from z and z is part of y
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002225
has_obo_namespace: uberon
id: develops_from_part_of
shorthand: develops_from_part_of

develops in
type: ObjectProperty
sub property of: developmentally_preceded_by
domain: UBERON_0001062
property chain axiom: directly develops from
property chain axiom: located in
has curation status: IAO_0000125
definition: x develops_in y if x is located in y whilst x is developing
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: EHDAA2
definition source: Jonathan Bard, EHDAA2
database_cross_reference: RO:0002226
has_obo_namespace: uberon
id: develops_in
shorthand: develops_in

obligate parasite of
type: ObjectProperty
sub property of: parasite of
definition: A sub-relation of parasite-of in which the parasite that cannot complete its life cycle without a host.

facultative parasite of
type: ObjectProperty
sub property of: parasite of
definition: A sub-relations of parasite-of in which the parasite that can complete its life cycle independent of a host.

ends
type: ObjectProperty
sub property of: part of
sub property of: temporally related to
inverse of: ends with
has curation status: IAO_0000125
definition: inverse of ends with
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002229
has_obo_namespace: uberon
id: ends
in_subset: eco subset
shorthand: ends

ends with
type: ObjectProperty
sub property of: has part
sub property of: temporally related to
type: TransitiveProperty
has curation status: IAO_0000125
definition: x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: finished by
database_cross_reference: RO:0002230
has_obo_namespace: uberon
id: ends_with
in_subset: eco subset
shorthand: ends_with

has start location
type: ObjectProperty
sub property of: has part that occurs in
domain: process
range: independent continuant
property chain axiom: starts with
property chain axiom: occurs in
has curation status: IAO_0000125
definition: x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: starts with process that occurs in
database_cross_reference: RO:0002231
in_subset: eco subset
shorthand: has_start_location

has end location
type: ObjectProperty
sub property of: has part that occurs in
domain: process
range: independent continuant
property chain axiom: ends with
property chain axiom: occurs in
has curation status: IAO_0000125
definition: x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: ends with process that occurs in
database_cross_reference: RO:0002232
in_subset: eco subset
shorthand: has_end_location

has input
type: ObjectProperty
sub property of: has participant
inverse of: input of
domain: process
property chain axiom: starts with
has curation status: IAO_0000125
definition: p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: consumes
database_cross_reference: RO:0002233
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
in_subset: eco subset
shorthand: has_input

has output
type: ObjectProperty
sub property of: has participant
inverse of: output of
property chain axiom: ends with
has curation status: IAO_0000125
definition: p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: produces
database_cross_reference: RO:0002234
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
in_subset: eco subset
shorthand: has_output

stem parasite of
type: ObjectProperty
sub property of: parasite of
definition: A parasite-of relationship in which the host is a plant and the parasite that attaches to the host stem (PO:0009047)

root parasite of
type: ObjectProperty
sub property of: parasite of
definition: A parasite-of relationship in which the host is a plant and the parasite that attaches to the host root (PO:0009005)

hemiparasite of
type: ObjectProperty
sub property of: parasite of
definition: A sub-relation of parasite-of in which the parasite is a plant, and the parasite is parasitic under natural conditions and is also photosynthetic to some degree. Hemiparasites may just obtain water and mineral nutrients from the host plant. Many obtain at least part of their organic nutrients from the host as well.

has component participant
type: ObjectProperty
sub property of: has participant
definition: X 'has component participant' Y means X 'has participant' Y and there is a cardinality constraint that specifies the numbers of Ys.
term editor: https://orcid.org/0000-0001-9625-1899
curator note: This object property is needed for axioms using has_participant with a cardinality contrainsts; e.g., has_particpant min 2 object. However, OWL does not permit cardinality constrains with object properties that have property chains (like has_particant) or are transitive (like has_part). If you need an axiom that says 'has_participant min 2 object', you should instead say 'has_component_participant min 2 object'.

has exposure receptor
type: ObjectProperty
sub property of: related via exposure to
definition: A broad relationship between an exposure event or process and any entity (e.g., an organism, organism population, or an organism part) that interacts with an exposure stimulus during the exposure event.
definition source: ExO:0000001

has exposure stressor
type: ObjectProperty
sub property of: has exposure stimulus
definition: A broad relationship between an exposure event or process and any agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event.
definition source: ExO:0000000

has exposure route
type: ObjectProperty
sub property of: related via exposure to
definition: A broad relationship between an exposure event or process and a process by which the exposure stressor comes into contact with the exposure receptor
definition source: ExO:0000055

has exposure transport path
type: ObjectProperty
sub property of: related via exposure to
definition: A broad relationship between an exposure event or process and the course takes from the source to the target.
definition source: http://purl.obolibrary.org/obo/ExO_0000004

related via exposure to
type: ObjectProperty
sub property of: causally related to
domain: COB_0001000
definition: Any relationship between an exposure event or process and any other entity.
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving exposure events or processes.

over-expressed in
type: ObjectProperty
sub property of: expressed in
definition: g is over-expressed in t iff g is expressed in t, and the expression level of g is increased relative to some background.

under-expressed in
type: ObjectProperty
sub property of: expressed in
definition: g is under-expressed in t iff g is expressed in t, and the expression level of g is decreased relative to some background.

has active ingredient
type: ObjectProperty
sub property of: has part
inverse of: active ingredient in
domain: material entity
range: material entity
example of usage: Any portion of roundup 'has active ingredient' some glyphosate
definition: A relationship that holds between a substance and a chemical entity, if the chemical entity is part of the substance, and the chemical entity forms the biologically active component of the substance.
has_exact_synonym: has active substance
has_related_synonym: has active pharmaceutical ingredient

active ingredient in
type: ObjectProperty
sub property of: part of
definition: inverse of has active ingredient
in_subset: defined by inverse

connecting branch of
type: ObjectProperty
sub property of: connected to
sub property of: in branching relationship with
inverse of: has connecting branch
example of usage: In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is connecting branch of S, and B1-1 as a connecting branch of B1.
definition: b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t.
nominally disjoint with: part of
database_cross_reference: RO:0002252
has_obo_namespace: uberon
id: connecting_branch_of
shorthand: connecting_branch_of

has connecting branch
type: ObjectProperty
sub property of: in branching relationship with
definition: inverse of connecting branch of
nominally disjoint with: has part
database_cross_reference: RO:0002253
in_subset: defined by inverse
shorthand: has_connecting_branch

has developmental contribution from
type: ObjectProperty
sub property of: developmentally_preceded_by
inverse of: developmentally contributes to
domain: UBERON_0001062
range: UBERON_0001062
property chain axiom: has part
property chain axiom: develops from
example of usage: Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]
has curation status: IAO_0000125
definition: x has developmental contribution from y iff x has some part z such that z develops from y
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002254
has_obo_namespace: uberon
id: has_developmental_contribution_from
shorthand: has_developmental_contribution_from

developmentally contributes to
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally contribute to
property chain axiom: develops into
property chain axiom: part of
has curation status: IAO_0000125
definition: inverse of has developmental contribution from
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002255
in_subset: defined by inverse
shorthand: developmentally_contributes_to

developmentally induced by
type: ObjectProperty
sub property of: developmentally_preceded_by
inverse of: developmentally induces
domain: UBERON_0000465
range: UBERON_0000465
has curation status: IAO_0000125
definition: t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T
term editor: https://orcid.org/0000-0001-9114-8737
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0002-7073-9172
alternative term: induced by
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20064205
definition source: Developmental Biology, Gilbert, 8th edition, figure 6.5(F)
definition source: GO:0001759
curator note: We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]
database_cross_reference: RO:0002256
has_obo_namespace: uberon
id: developmentally_induced_by
shorthand: developmentally_induced_by

developmentally induces
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally induce
has curation status: IAO_0000125
definition: Inverse of developmentally induced by
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002257
shorthand: developmentally_induces

developmentally_preceded_by
type: ObjectProperty
sub property of: developmentally related to
inverse of: developmentally succeeded by
domain: continuant
range: continuant
has curation status: IAO_0000125
definition: Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
definition: X developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p.
editor note: false
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: In general you should not use this relation to make assertions - use one of the more specific relations below this one
created by: Laurel_Cooper
creation date: 2013-06-27T13:16:56Z
database_cross_reference: RO:0002258
has_obo_namespace: plant_ontology
id: developmentally_preceded_by
shorthand: developmentally_preceded_by
comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from
label: developmentally preceded by

Axiom
annotated source: developmentally_preceded_by
annotated property: definition
annotated target: X developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p.
database_cross_reference: RO:0002258

has biological role
type: ObjectProperty
sub property of: has role
definition: c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)

has application role
type: ObjectProperty
sub property of: has role
definition: c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)

has chemical role
type: ObjectProperty
sub property of: has role
definition: c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)

acts upstream of
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of
example of usage: A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision.
definition: c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
database_cross_reference: RO:0002263
in_subset: valid_for_go_gp2term
shorthand: acts_upstream_of

acts upstream of or within
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: enables
property chain axiom: causally upstream of or within
example of usage: A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway.
definition: c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
database_cross_reference: RO:0002264
has_related_synonym: affects
in_subset: valid_for_go_gp2term
shorthand: acts_upstream_of_or_within

developmentally replaces
type: ObjectProperty
sub property of: developmentally_preceded_by
has curation status: IAO_0000125
definition: x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else
editor note: This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: replaces
database_cross_reference: RO:0002285
has_obo_namespace: uberon
id: developmentally_replaces
shorthand: developmentally_replaces

developmentally succeeded by
type: ObjectProperty
sub property of: has developmental potential involving
has curation status: IAO_0000125
definition: Inverse of developmentally preceded by
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002286
shorthand: developmentally_succeeded_by

part of developmental precursor of
type: ObjectProperty
sub property of: developmentally succeeded by
property chain axiom: part of
property chain axiom: directly develops into
example of usage: 'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue
has curation status: IAO_0000125
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002287
shorthand: part_of_developmental_precursor_of

ubiquitously expressed in
type: ObjectProperty
sub property of: expressed in
inverse of: ubiquitously expresses
has curation status: IAO_0000125
definition: x is ubiquitously expressed in y if and only if x is expressed in y, and the majority of cells in y express x
editor note: Revisit this term after coordinating with SO/SOM. The domain of this relation should be a sequence, as an instance of a DNA molecule is only expressed in the cell of which it is a part.
term editor: https://orcid.org/0000-0002-6601-2165

expresses
type: ObjectProperty
sub property of: genomically related to
has curation status: IAO_0000125
definition: y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process.
term editor: https://orcid.org/0000-0002-6601-2165

ubiquitously expresses
type: ObjectProperty
sub property of: expresses
has curation status: IAO_0000125
definition: inverse of ubiquiotously expressed in
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: defined by inverse

results in developmental progression of
type: ObjectProperty
sub property of: developmentally related to
domain: GO_0008150
range: UBERON_0001062
has curation status: IAO_0000125
definition: p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss).
editor note: This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002295
shorthand: results_in_developmental_progression_of

results in development of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
example of usage: every flower development (GO:0009908) results in development of some flower (PO:0009046)
has curation status: IAO_0000125
definition: p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.geneontology.org/GO.doc.development.shtml
database_cross_reference: RO:0002296
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: results_in_development_of

results in formation of
type: ObjectProperty
sub property of: has output
sub property of: results in developmental progression of
inverse of: formed as result of
example of usage: an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists.
example of usage: every "endocardial cushion formation" (GO:0003272) results_in_formation_of some "endocardial cushion" (UBERON:0002062)
has curation status: IAO_0000125
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: GOC:mtg_berkeley_2013
database_cross_reference: RO:0002297
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: results_in_formation_of_anatomical_entity
label: results in formation of anatomical entity

results in morphogenesis of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
example of usage: an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape.
example of usage: tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)
has curation status: IAO_0000125
definition: The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: GOC:mtg_berkeley_2013
database_cross_reference: RO:0002298
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: results_in_morphogenesis_of

results in maturation of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
example of usage: an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process
example of usage: bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)
has curation status: IAO_0000125
definition: The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: GOC:mtg_berkeley_2013
database_cross_reference: RO:0002299
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: results_in_maturation_of

results in disappearance of
type: ObjectProperty
sub property of: results in ending of
example of usage: foramen ovale closure SubClassOf results in disappearance of foramen ovale
has curation status: IAO_0000125
term editor: https://orcid.org/0000-0002-6601-2165
curator note: May be merged into parent relation

results in developmental regression of
type: ObjectProperty
sub property of: results in ending of
example of usage: every mullerian duct regression (GO:0001880) results in regression of some mullerian duct (UBERON:0003890)
has curation status: IAO_0000125
term editor: https://orcid.org/0000-0002-6601-2165
curator note: May be merged into parent relation

is treated by substance
type: ObjectProperty
sub property of: causally related to
inverse of: is substance that treats
definition: Inverse of 'is substance that treats'
creator: https://orcid.org/0000-0002-6601-2165
in_subset: defined by inverse

has habitat
type: ObjectProperty
sub property of: ecologically related to
domain: OBI_0100026
range: ENVO_01000254
example of usage: Hydrozoa (NCBITaxon_6074) SubClassOf 'has habitat' some 'Hydrozoa habitat' where 'Hydrozoa habitat' SubClassOf overlaps some ('marine environment' (ENVO_00000569) and 'freshwater environment' (ENVO_01000306) and 'wetland' (ENVO_00000043)) and 'has part' some (freshwater (ENVO_00002011) or 'sea water' (ENVO_00002149)) -- http://eol.org/pages/1795/overview
has curation status: IAO_0000428
definition: x 'has habitat' y if and only if: x is an organism, y is a habitat, and y can sustain and allow the growth of a population of xs.
term editor: https://orcid.org/0000-0002-4366-3088
term editor: Pier Buttigieg
alternative term: adapted for living in
in_subset: eco subset
comment: A population of xs will possess adaptations (either evolved naturally or via artifical selection) which permit it to exist and grow in y.

causally upstream of, positive effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, positive effect
definition: p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
is positive form of: causally upstream of
creator: https://orcid.org/0000-0002-6601-2165
creator: cjm
database_cross_reference: RO:0002304
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_gocam
shorthand: causally_upstream_of,_positive_effect
comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y

causally upstream of, negative effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, negative effect
definition: p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
is negative form of: causally upstream of
creator: https://orcid.org/0000-0002-6601-2165
creator: cjm
database_cross_reference: RO:0002305
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_gocam
shorthand: causally_upstream_of,_negative_effect

has exposure stimulus
type: ObjectProperty
sub property of: related via exposure to
definition: A relationship between an exposure event or process and any agent, stimulus, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event.
contributor: https://orcid.org/0000-0001-6996-0040
contributor: https://orcid.org/0000-0002-6601-2165
contributor: https://orcid.org/0000-0002-8461-9745
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-06-05T17:35:04Z

evolutionary variant of
type: ObjectProperty
sub property of: evolutionarily related to
term editor: https://orcid.org/0000-0002-6601-2165

transports or maintains localization of
type: ObjectProperty
sub property of: related via localization to
sub property of: results in changes to anatomical or cellular structure
definition: Holds between p and c when p is a localization process (localization covers maintenance of localization as well as its establishment) and the outcome of this process is to regulate the localization of c.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: regulates localization of
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam

characteristic of part of
type: ObjectProperty
sub property of: depends on
property chain axiom: characteristic of
property chain axiom: part of
definition: q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
editor note: Because part_of is transitive, inheres in is a sub-relation of characteristic of part of
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: inheres in part of
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20064205
temporal interpretation: RO_0001901
database_cross_reference: RO:0002314
shorthand: characteristic_of_part_of

Axiom
annotated source: characteristic of part of
annotated property: propertyChainAxiom
annotated target: characteristic of
annotated target: part of
RO_0002582: true

results in acquisition of features of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
range: UBERON_0000061
example of usage: an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast.
definition: The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity
term editor: https://orcid.org/0000-0002-6601-2165
definition source: GOC:mtg_berkeley_2013
database_cross_reference: RO:0002315
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: results_in_acquisition_of_features_of

evolutionarily related to
type: ObjectProperty
definition: A relationship that holds via some environmental process
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution.
database_cross_reference: RO:0002320
shorthand: evolutionarily_related_to

ecologically related to
type: ObjectProperty
definition: A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)
editor note: Awaiting class for domain/range constraint, see: https://github.com/OBOFoundry/Experimental-OBO-Core/issues/6
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving ecological interactions
in_subset: eco subset

confers advantage in
type: ObjectProperty
sub property of: ecologically related to
range: ENVO_01000254
editor note: An experimental relation currently used to connect a feature possessed by an organism (e.g. anatomical structure, biological process, phenotype or quality) to a habitat or environment in which that feature is well suited, adapted or provides a reproductive advantage for the organism. For example, fins to an aquatic environment. Usually this will mean that the structure is adapted for this environment, but we avoid saying this directly - primitive forms of the structure may not have evolved specifically for that environment (for example, early wings were not necessarily adapted for an aerial environment). Note also that this is a statement about the general class of structures - not every instance of a limb need confer an advantage for a terrestrial environment, e.g. if the limb is vestigial.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: adapted for
in_subset: eco subset

mereotopologically related to
type: ObjectProperty
definition: A mereological relationship or a topological relationship
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
temporal interpretation: RO_0001901
database_cross_reference: RO:0002323
shorthand: mereotopologically_related_to

developmentally related to
type: ObjectProperty
definition: A relationship that holds between entities participating in some developmental process (GO:0032502)
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development
database_cross_reference: RO:0002324
shorthand: developmentally_related_to

colocalizes with
type: ObjectProperty
sub property of: mereotopologically related to
domain: material entity
range: material entity
example of usage: Clp1p relocalizes from the nucleolus to the spindle and site of cell division; i.e. it is associated transiently with the spindle pole body and the contractile ring (evidence from GFP fusion). Clp1p colocalizes_with spindle pole body (GO:0005816) and contractile ring (GO:0005826)
definition: a colocalizes_with b if and only if a is transiently or peripherally associated with b[GO].
term editor: https://orcid.org/0000-0002-6601-2165
curator note: In the context of the Gene Ontology, colocalizes_with may be used for annotating to cellular component terms[GO]
in_subset: valid_for_go_gp2term

contributes to
type: ObjectProperty
sub property of: capable of part of
sub property of: part of structure that is capable of
example of usage: ATP citrate lyase (ACL) in Arabidopsis: it is a heterooctamer, composed of two types of subunits, ACLA and ACLB in a A(4)B(4) stoichiometry. Neither of the subunits expressed alone give ACL activity, but co-expression results in ACL activity. Both subunits contribute_to the ATP citrate lyase activity.
example of usage: Subunits of nuclear RNA polymerases: none of the individual subunits have RNA polymerase activity, yet all of these subunits contribute_to DNA-dependent RNA polymerase activity.
example of usage: eIF2: has three subunits (alpha, beta, gamma); one binds GTP; one binds RNA; the whole complex binds the ribosome (all three subunits are required for ribosome binding). So one subunit is annotated to GTP binding and one to RNA binding without qualifiers, and all three stand in the contributes_to relationship to "ribosome binding". And all three are part_of an eIF2 complex
editor note: We would like to say if and only if exists c', p' c part_of c' and c' capable_of p and c capable_of p' and p' part_of p then c contributes_to p However, this is not possible in OWL. We instead make this relation a sub-relation of the two chains, which gives us the inference in the one direction.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: In the context of the Gene Ontology, contributes_to may be used only with classes from the molecular function ontology.
in_subset: valid_for_go_gp2term

enables
type: ObjectProperty
sub property of: capable of
inverse of: enabled by
property chain axiom: has part
property chain axiom: has component activity
example of usage: a particular instances of akt-2 enables some instance of protein kinase activity
definition: c enables p iff c is capable of p and c acts to execute p.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: catalyzes
alternative term: executes
alternative term: has
alternative term: is catalyzing
alternative term: is executing
curator note: This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized.
database_cross_reference: RO:0002327
in_subset: valid_for_go_gp2term
shorthand: enables

functionally related to
type: ObjectProperty
definition: A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: This is a grouping relation that collects relations used for the purpose of connecting structure and function
database_cross_reference: RO:0002328
has_obo_namespace: uberon
id: functionally_related_to
shorthand: functionally_related_to

part of structure that is capable of
type: ObjectProperty
sub property of: functionally related to
property chain axiom: part of
property chain axiom: capable of
definition: this relation holds between c and p when c is part of some c', and c' is capable of p.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: false
database_cross_reference: RO:0002329
shorthand: part_of_structure_that_is_capable_of

Axiom
annotated source: part of structure that is capable of
annotated property: propertyChainAxiom
annotated target: part of
annotated target: capable of
is a defining property chain axiom: true

genomically related to
type: ObjectProperty
domain: continuant
range: continuant
definition: holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.
term editor: https://orcid.org/0000-0002-6601-2165
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism

involved in
type: ObjectProperty
sub property of: participates in
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: part of
definition: c involved_in p if and only if c enables some process p', and p' is part of p
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: actively involved in
alternative term: enables part of
database_cross_reference: RO:0002331
shorthand: involved_in

regulates levels of
type: ObjectProperty
sub property of: functionally related to
domain: process
range: material entity
example of usage: every cellular sphingolipid homeostasis process regulates_level_of some sphingolipid
definition: p regulates levels of c if p regulates some amount (PATO:0000070) of c
term editor: https://orcid.org/0000-0002-6601-2165
definition source: causal-relations
OBO foundry unique label: regulates levels of (process to entity)

enabled by
type: ObjectProperty
sub property of: has participant
sub property of: functionally related to
definition: inverse of enables
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002333
in_subset: valid_for_gocam
shorthand: enabled_by

regulated by
type: ObjectProperty
sub property of: causally downstream of or within
type: TransitiveProperty
domain: process
range: process
definition: inverse of regulates
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
OBO foundry unique label: regulated by (processual)
database_cross_reference: RO:0002334
in_subset: defined by inverse
shorthand: regulated_by

negatively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of negatively regulates
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002335
in_subset: defined by inverse
shorthand: negatively_regulated_by

positively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of positively regulates
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002336
in_subset: defined by inverse
shorthand: positively_regulated_by

related via localization to
type: ObjectProperty
domain: process
range: continuant
definition: A relationship that holds via some process of localization
term editor: https://orcid.org/0000-0002-6601-2165
curator note: Do not use this relation directly. It is a grouping relation.
database_cross_reference: RO:0002337
shorthand: related_via_localization_to

has target start location
type: ObjectProperty
sub property of: results in transport to from or in
property chain axiom: part of
definition: This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002338
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: has_target_start_location

has target end location
type: ObjectProperty
sub property of: results in transport to from or in
property chain axiom: part of
definition: This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002339
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: has_target_end_location

imports
type: ObjectProperty
sub property of: transports
definition: Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the start location of c is part of the region that surrounds s.
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: valid_for_go_ontology

results in transport along
type: ObjectProperty
sub property of: related via localization to
definition: Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002341
shorthand: results_in_transport_along

results in transport across
type: ObjectProperty
sub property of: occurs across
sub property of: results in transport to from or in
definition: Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002342
in_subset: valid_for_go_ontology
shorthand: results_in_transport_across

results in growth of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
example of usage: 'pollen tube growth' results_in growth_of some 'pollen tube'
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002343
shorthand: results_in_growth_of

results in transport to from or in
type: ObjectProperty
sub property of: related via localization to
example of usage: 'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002344
shorthand: results_in_transport_to_from_or_in

exports
type: ObjectProperty
sub property of: transports
definition: Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the end location of c is part of the region that surrounds s.
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: valid_for_go_ontology

results in commitment to
type: ObjectProperty
sub property of: results in developmental progression of
range: cell
example of usage: an annotation of gene X to cell commitment with results_in_commitment_to CL:0000540 (neuron) means that at the end of the process an unspecified cell has been specified and determined to develop into a neuron.
definition: p 'results in commitment to' c if and only if p is a developmental process and c is a cell and p results in the state of c changing such that is can only develop into a single cell type.
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam

results in determination of
type: ObjectProperty
sub property of: results in developmental progression of
range: cell
definition: p 'results in determination of' c if and only if p is a developmental process and c is a cell and p results in the state of c changing to be determined. Once a cell becomes determined, it becomes committed to differentiate down a particular pathway regardless of its environment.
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam

member of
type: ObjectProperty
sub property of: part of
inverse of: has member
example of usage: An organism that is a member of a population of organisms
definition: is member of is a mereological relation between a item and a collection.
alternative term: is member of
alternative term: member part of
definition source: SIO
temporal interpretation: RO_0001901
database_cross_reference: RO:0002350
shorthand: member_of

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
definition: has member is a mereological relation between a collection and an item.
definition source: SIO
temporal interpretation: RO_0001901
database_cross_reference: RO:0002351
has_obo_namespace: uberon
id: has_member
shorthand: has_member

input of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has input
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002352
has_obo_namespace: uberon
id: input_of
in_subset: defined by inverse
in_subset: eco subset
shorthand: input_of

output of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has output
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002353
has_obo_namespace: uberon
id: output_of
in_subset: defined by inverse
in_subset: eco subset
shorthand: output_of

formed as result of
type: ObjectProperty
sub property of: output of
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002354
shorthand: formed_as_result_of

results in structural organization of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
definition: A relationship between a process and an anatomical entity such that the process contributes to the act of creating the structural organization of the anatomical entity.
term editor: https://orcid.org/0000-0002-6601-2165

results in specification of
type: ObjectProperty
sub property of: results in developmental progression of
range: cell
definition: The relationship linking a cell and its participation in a process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam

results in developmental induction of
type: ObjectProperty
sub property of: results in developmental progression of
definition: p results in developmental induction of c if and only if p is a collection of cell-cell signaling processes that signal to a neighbouring tissue that is the precursor of the mature c, where the signaling results in the commitment to cell types necessary for the formation of c.
term editor: https://orcid.org/0000-0002-6601-2165

has dendrite location
type: ObjectProperty
sub property of: overlaps
term editor: https://orcid.org/0000-0002-6601-2165
source: http://neurolex.org/wiki/Property:DendriteLocation

attached to
type: ObjectProperty
sub property of: connected to
sub property of: attached to part of
type: SymmetricProperty
definition: a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
OBO foundry unique label: attached to (anatomical structure to anatomical structure)
database_cross_reference: RO:0002371
has_obo_namespace: uberon
id: attaches_to
in_subset: eco subset
shorthand: attached_to
shorthand: attaches_to

has muscle origin
type: ObjectProperty
sub property of: attached to
sub property of: biomechanically related to
domain: UBERON_0000061
definition: m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: Wikipedia:Insertion_(anatomy)
database_cross_reference: RO:0002372
has_obo_namespace: uberon
id: has_muscle_origin
shorthand: has_muscle_origin

Axiom
annotated source: has muscle origin
annotated property: domain
annotated target: UBERON_0000061
comment: We need to import uberon muscle to create a stricter domain constraint

has muscle insertion
type: ObjectProperty
sub property of: attached to
sub property of: biomechanically related to
domain: UBERON_0000061
definition: m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: Wikipedia:Insertion_(anatomy)
database_cross_reference: RO:0002373
has_obo_namespace: uberon
id: has_muscle_insertion
shorthand: has_muscle_insertion

Axiom
annotated source: has muscle insertion
annotated property: domain
annotated target: UBERON_0000061
editor note: We need to import uberon muscle into RO to use as a stricter domain constraint

derived from ancestral fusion of
type: ObjectProperty
sub property of: derived by descent from
example of usage: false
has curation status: IAO_0000428
definition: x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
has_broad_synonym: has fused element
comment: A has_fused_element B does not imply that A has_part some B: rather than A has_part some B', where B' that has some evolutionary relationship to B.

in branching relationship with
type: ObjectProperty
sub property of: mereotopologically related to
domain: material entity
range: material entity
has curation status: IAO_0000428
definition: A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships
curator note: This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)
nominally disjoint with: part of
database_cross_reference: RO:0002375
shorthand: in_branching_relationship_with

tributary of
type: ObjectProperty
sub property of: connected to
sub property of: in branching relationship with
example of usage: Deschutes River tributary_of Columbia River
example of usage: inferior epigastric vein tributary_of external iliac vein
has curation status: IAO_0000428
definition: x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: drains into
alternative term: drains to
alternative term: tributary channel of
definition source: http://en.wikipedia.org/wiki/Tributary
definition source: http://www.medindia.net/glossary/venous_tributary.htm
curator note: This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries)
database_cross_reference: RO:0002376
has_obo_namespace: uberon
id: tributary_of
in_subset: eco subset
shorthand: tributary_of

distributary of
type: ObjectProperty
sub property of: connected to
sub property of: in branching relationship with
example of usage: Deschutes River distributary_of Little Lava Lake
has curation status: IAO_0000428
definition: x distributary_of y if and only if x is capable of channeling the flow of a substance to y, where y channels less of the substance than x
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: branch of
alternative term: distributary channel of
definition source: http://en.wikipedia.org/wiki/Distributary
in_subset: eco subset
comment: This is both a mereotopological relationship and a relationship defined in connection to processes. It concerns both the connecting structure, and how this structure is disposed to causally affect flow processes

anabranch of
type: ObjectProperty
sub property of: distributary of
sub property of:
  inverse of: tributary of
property disjoint with: proper distributary of
property disjoint with: proper tributary of
has curation status: IAO_0000428
definition: x anabranch_of y if x is a distributary of y (i.e. it channels a from a larger flow from y) and x ultimately channels the flow back into y.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: anastomoses with
in_subset: eco subset

spatially coextensive with
type: ObjectProperty
sub property of: overlaps
property chain axiom: located in
property chain axiom:
  inverse of: located in
example of usage: A lump of clay and a statue
definition: x spatially_coextensive_with y if and inly if x and y have the same location
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: This relation is added for formal completeness. It is unlikely to be used in many practical scenarios
database_cross_reference: RO:0002379
shorthand: spatially_coextensive_with

branching part of
type: ObjectProperty
sub property of: part of
sub property of: in branching relationship with
inverse of: has branching part
range: Restriction
  on property: has characteristic
  some values from: PATO_0000402
property chain axiom: distributary of
property chain axiom: main stem of
example of usage: In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S
definition: x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002380
has_obo_namespace: uberon
id: branching_part_of
in_subset: eco subset
shorthand: branching_part_of

main stem of
type: ObjectProperty
sub property of: part of
sub property of: in branching relationship with
example of usage: In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, S is the main stem of T. There are no other main stems. If we were to slice off S to get a new tree T', rooted at the root of B1, then B1 would be the main stem of T'.
has curation status: IAO_0000428
definition: x main_stem_of y if y is a branching structure and x is a channel that traces a linear path through y, such that x has higher capacity than any other such path.
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

proper distributary of
type: ObjectProperty
sub property of: distributary of
has curation status: IAO_0000428
definition: x proper_distributary_of y iff x distributary_of y and x does not flow back into y
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

proper tributary of
type: ObjectProperty
sub property of: tributary of
has curation status: IAO_0000428
definition: x proper_tributary_of y iff x tributary_of y and x does not originate from y
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

has developmental potential involving
type: ObjectProperty
sub property of: developmentally related to
domain: UBERON_0001062
range: UBERON_0001062
has curation status: IAO_0000428
definition: x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002384
shorthand: has_developmental_potential_involving

has potential to developmentally contribute to
type: ObjectProperty
sub property of: has developmental potential involving
has curation status: IAO_0000428
definition: x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002385
has_obo_namespace: uberon
id: has_potential_to_developmentally_contribute_to
shorthand: has_potential_to_developmentally_contribute_to

has potential to developmentally induce
type: ObjectProperty
sub property of: has developmental potential involving
has curation status: IAO_0000428
definition: x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002386
shorthand: has_potential_to_developmentally_induce

has potential to develop into
type: ObjectProperty
sub property of: has developmental potential involving
has curation status: IAO_0000428
definition: x has the potential to develop into y iff x develops into y or if x is capable of developing into y
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002387
has_obo_namespace: uberon
id: has_potential_to_develop_into
shorthand: has_potential_to_develop_into

has potential to directly develop into
type: ObjectProperty
sub property of: has potential to develop into
has curation status: IAO_0000428
definition: x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002388
shorthand: has_potential_to_directly_develop_into

has direct input
type: ObjectProperty
sub property of: has input
property chain axiom: starts with
example of usage: 'protein catabolic process' SubClassOf has_direct_input some protein
has curation status: IAO_0000428
definition: p has direct input c iff c is a participant in p, c is present at the start of p, and the state of c is modified during p.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: directly consumes
curator note: This is likely to be obsoleted. A candidate replacement would be a new relation 'has bound input' or 'has substrate'

causally downstream of
type: ObjectProperty
sub property of: preceded by
sub property of: causally downstream of or within
inverse of: causally upstream of
has curation status: IAO_0000428
definition: inverse of upstream of
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002404
shorthand: causally_downstream_of

immediately causally downstream of
type: ObjectProperty
sub property of: immediately preceded by
sub property of: causally downstream of
inverse of: immediately causally upstream of
has curation status: IAO_0000428
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002405
shorthand: immediately_causally_downstream_of

indirectly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: indirectly regulates
type: TransitiveProperty
property chain axiom: directly positively regulates
property chain axiom: indirectly negatively regulates
definition: p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: indirectly activates
is indirect form of: positively regulates
database_cross_reference: RO:0002407
shorthand: indirectly_positively_regulates

indirectly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: indirectly regulates
type: TransitiveProperty
property chain axiom: directly negatively regulates
definition: p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: indirectly inhibits
is indirect form of: negatively regulates
database_cross_reference: RO:0002409
shorthand: indirectly_negatively_regulates

causally related to
type: ObjectProperty
definition: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
editor note: This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yie…
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
database_cross_reference: RO:0002410
shorthand: causally_related_to

Axiom
annotated source: causally related to
annotated property: definition
annotated target: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
database_cross_reference: https://en.wikipedia.org/wiki/Causality

causally upstream of
type: ObjectProperty
sub property of: precedes
sub property of: causally upstream of or within
type: TransitiveProperty
definition: p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002411
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_gocam
shorthand: causally_upstream_of

immediately causally upstream of
type: ObjectProperty
sub property of: immediately precedes
sub property of: causally upstream of
definition: p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
is direct form of: causally upstream of
database_cross_reference: RO:0002412
shorthand: immediately_causally_upstream_of

provides input for
type: ObjectProperty
sub property of: immediately causally upstream of
sub property of: transitively provides input for
definition: p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: directly provides input for
definition source: causal-relations
OBO foundry unique label: directly provides input for (process to process)

transitively provides input for
type: ObjectProperty
sub property of: causally upstream of or within, positive effect
type: TransitiveProperty
domain: process
range: process
has curation status: IAO_0000428
definition: transitive form of directly_provides_input_for
term editor: https://orcid.org/0000-0002-6601-2165
curator note: This is a grouping relation that should probably not be used in annotation. Consider instead the child relation 'provides input for'.
OBO foundry unique label: transitively provides input for (process to process)

causally upstream of or within
type: ObjectProperty
sub property of: causal relation between processes
inverse of: causally downstream of or within
type: TransitiveProperty
definition: p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
editor note: We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: influences (processual)
database_cross_reference: RO:0002418
has_related_synonym: affects
shorthand: causally_upstream_of_or_within

differs in
type: ObjectProperty
editor note: false
term editor: https://orcid.org/0000-0002-6601-2165
comment: This is an exploratory relation

differs in attribute of
type: ObjectProperty
sub property of: differs in
range: Class
  union of: independent continuant
  union of: process
term editor: https://orcid.org/0000-0002-6601-2165

differs in attribute
type: ObjectProperty
sub property of: differs in
range: characteristic
term editor: https://orcid.org/0000-0002-6601-2165

causally downstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
definition: inverse of causally upstream of or within
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
database_cross_reference: RO:0002427
in_subset: defined by inverse
shorthand: causally_downstream_of_or_within

involved in regulation of
type: ObjectProperty
sub property of: acts upstream of
sub property of: involved in or involved in regulation of
property chain axiom: enables
property chain axiom: regulates (processual)
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' regulates some p
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002428
shorthand: involved_in_regulation_of

involved in positive regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: positively regulates
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' positively regulates some p
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
is positive form of: involved in regulation of
database_cross_reference: RO:0002429
shorthand: involved_in_positive_regulation_of

involved in negative regulation of
type: ObjectProperty
sub property of: involved in regulation of
property chain axiom: enables
property chain axiom: negatively regulates
property chain axiom: involved in
definition: c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
is negative form of: involved in regulation of
database_cross_reference: RO:0002430
shorthand: involved_in_negative_regulation_of

involved in or involved in regulation of
type: ObjectProperty
sub property of: acts upstream of or within
sub property of: functionally related to
sub property of: causal agent in process
definition: c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
editor note: OWL does not allow defining object properties via a Union
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: involved in or reguates
database_cross_reference: RO:0002431
shorthand: involved_in_or_involved_in_regulation_of

is active in
type: ObjectProperty
sub property of: overlaps
sub property of: functionally related to
property chain axiom: enables
property chain axiom: occurs in
example of usage: A protein that enables activity in a cytosol.
definition: c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: executes activity in
database_cross_reference: RO:0002432
has_exact_synonym: enables activity in
shorthand: is_active_in

Axiom
annotated source: is active in
annotated property: propertyChainAxiom
annotated target: enables
annotated target: occurs in
is a defining property chain axiom: true

Axiom
annotated source: is active in
annotated property: definition
annotated target: c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
database_cross_reference: https://orcid.org/0000-0002-6601-2165
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: is active in
annotated property: definition
annotated target: c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
database_cross_reference: GOC:cjm
database_cross_reference: GOC:dos

contributes to morphology of
type: ObjectProperty
sub property of: overlaps
definition: p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm.
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002433
has_obo_namespace: uberon
id: contributes_to_morphology_of
shorthand: contributes_to_morphology_of

interacts with
type: ObjectProperty
type: SymmetricProperty
domain: material entity
range: material entity
definition: A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
editor note: This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact.
editor note: Considering relabeling as 'pairwise interacts with'
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules.
database_cross_reference: RO:0002434
has_exact_synonym: in pairwise interaction with
in_subset: eco subset
shorthand: interacts_with

genetically interacts with
type: ObjectProperty
sub property of: interacts with
type: SymmetricProperty
editor note: An interaction that holds between two genetic entities (genes, alleles) through some genetic interaction (e.g. epistasis)
term editor: https://orcid.org/0000-0002-6601-2165

molecularly interacts with
type: ObjectProperty
sub property of: interacts with
type: SymmetricProperty
definition: An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: binds
alternative term: molecularly binds with
database_cross_reference: RO:0002436
shorthand: molecularly_interacts_with

biotically interacts with
type: ObjectProperty
sub property of: ecologically related to
sub property of: interacts with
type: SymmetricProperty
domain: material entity
range: material entity
definition: An interaction relationship in which at least one of the partners is an organism and the other is either an organism or an abiotic entity with which the organism interacts.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: interacts with on organism level
in_subset: eco subset

trophically interacts with
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with
definition: An interaction relationship in which the partners are related via a feeding relationship.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
in_subset: eco subset

preys on
type: ObjectProperty
sub property of: trophically interacts with
inverse of: preyed upon by
example of usage: A wasp killing a Monarch larva in order to feed to offspring [http://www.inaturalist.org/observations/2942824]
example of usage: Baleen whale preys on krill
definition: An interaction relationship involving a predation process, where the subject kills the target in order to eat it or to feed to siblings, offspring or group members
term editor: https://orcid.org/0000-0001-7134-3324
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0003-3138-4118
alternative term: is subject of predation interaction with
alternative term: preys upon
in_subset: eco subset

symbiotically interacts with
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with
type: SymmetricProperty
property chain axiom: partner in
property chain axiom: is symbiosis
property chain axiom:
  inverse of: partner in
definition: A biotic interaction in which the two organisms live together in more or less intimate association.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/19278549
curator note: We follow GO and PAMGO in using 'symbiosis' as the broad term encompassing mutualism through parasitism
in_subset: eco subset

commensually interacts with
type: ObjectProperty
sub property of: symbiotically interacts with
property chain axiom: partner in
property chain axiom: is commensalism
property chain axiom:
  inverse of: partner in
definition: An interaction relationship between two organisms living together in more or less intimate association in a relationship in which one benefits and the other is unaffected (GO).
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/19278549
in_subset: eco subset

mutualistically interacts with
type: ObjectProperty
sub property of: symbiotically interacts with
property chain axiom: partner in
property chain axiom: is mutualism
property chain axiom:
  inverse of: partner in
definition: An interaction relationship between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other (GO).
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/19278549
in_subset: eco subset

interacts with via parasite-host interaction
type: ObjectProperty
sub property of: symbiotically interacts with
property chain axiom: partner in
property chain axiom: is parasitism
property chain axiom:
  inverse of: partner in
definition: An interaction relationship between two organisms living together in more or less intimate association in a relationship in which association is disadvantageous or destructive to one of the organisms (GO).
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/19278549
curator note: This relation groups a pair of inverse relations, parasite of and parasitized by
in_subset: eco subset

parasite of
type: ObjectProperty
sub property of: interacts with via parasite-host interaction
sub property of: has host
inverse of: parasitized by
property chain axiom: subject participant in
property chain axiom: is parasitism
property chain axiom:
  inverse of: target participant in
example of usage: Pediculus humanus capitis parasite of human
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: parasitizes
has_exact_synonym: direct parasite of
in_subset: eco subset

parasitized by
type: ObjectProperty
sub property of: interacts with via parasite-host interaction
sub property of: host of
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: has parasite
alternative term: parasitised by
has_exact_synonym: directly parasitized by
in_subset: eco subset

participates in a abiotic-biotic interaction with
type: ObjectProperty
sub property of: biotically interacts with
example of usage: Porifiera attaches to substrate
definition: A biotic interaction relationship in which one partner is an organism and the other partner is inorganic. For example, the relationship between a sponge and the substrate to which is it anchored.
term editor: https://orcid.org/0000-0002-6601-2165
has_related_synonym: semibiotically interacts with
in_subset: eco subset

phosphorylates
type: ObjectProperty
sub property of: molecularly interacts with
property chain axiom: capable of
property chain axiom: is kinase activity
property chain axiom: has direct input
editor note: Axiomatization to GO to be added later
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
alternative term: An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.
database_cross_reference: RO:0002447
shorthand: phosphorylates

directly regulates activity of
type: ObjectProperty
sub property of: molecularly interacts with
sub property of: regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: regulates (processual)
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0003-4639-4431
term editor: Chris Mungall
term editor: Vasundra Touré
database_cross_reference: RO:0002448
has_exact_synonym: molecularly controls
shorthand: directly_regulates_activity_of

directly negatively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly negatively regulates
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0003-4639-4431
term editor: Chris Mungall
term editor: Vasundra Touré
alternative term: directly inhibits
database_cross_reference: RO:0002449
has_exact_synonym: molecularly decreases activity of
shorthand: directly_negatively_regulates_activity_of

directly positively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
domain: material entity
range: material entity
property chain axiom: enables
property chain axiom: directly positively regulates
property chain axiom: enabled by
definition: The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0003-4639-4431
term editor: Chris Mungall
term editor: Vasundra Touré
alternative term: directly activates
database_cross_reference: RO:0002450
has_exact_synonym: molecularly increases activity of
shorthand: directly_positively_regulates_activity_of

transmitted by
type: ObjectProperty
sub property of: ecologically related to
example of usage: all dengue disease transmitted by some mosquito
definition: A relationship that holds between a disease and organism
editor note: Add domain and range constraints
term editor: https://orcid.org/0000-0002-6601-2165

has symptom
type: ObjectProperty
sub property of: has phenotype
domain: OGMS_0000031
definition: A relation that holds between a disease or an organism and a phenotype
term editor: https://orcid.org/0000-0002-6601-2165

host of
type: ObjectProperty
sub property of: symbiotically interacts with
term editor: https://orcid.org/0000-0002-6601-2165
curator note: The term host is usually used for the larger (macro) of the two members of a symbiosis (GO)
in_subset: eco subset

has host
type: ObjectProperty
sub property of: symbiotically interacts with
definition: X 'has host' y if and only if: x is an organism, y is an organism, and x can live on the surface of or within the body of y
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

pollinates
type: ObjectProperty
sub property of: mutualistically interacts with
inverse of: pollinated by
example of usage: Bees pollinate Flowers
editor note: This relation is intended to be used for biotic pollination - e.g. a bee pollinating a flowering plant. Some kinds of pollination may be semibiotic - e.g. wind can have the role of pollinator. We would use a separate relation for this.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: is subject of pollination interaction with
in_subset: eco subset

pollinated by
type: ObjectProperty
sub property of: mutualistically interacts with
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: has polinator
alternative term: is target of pollination interaction with
in_subset: eco subset

acquires nutrients from
type: ObjectProperty
sub property of: trophically interacts with
inverse of: provides nutrients for
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Intended to be used when the target of the relation is not itself consumed, and does not have integral parts consumed, but provided nutrients in some other fashion.
in_subset: eco subset

preyed upon by
type: ObjectProperty
sub property of: trophically interacts with
definition: inverse of preys on
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: has predator
alternative term: is target of predation interaction with
in_subset: defined by inverse
in_subset: eco subset

is vector for
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with
inverse of: has vector
example of usage: Anopheles is a vector for Plasmodium
term editor: https://orcid.org/0000-0002-6601-2165
definition source: a is a vector for b if a carries and transmits an infectious pathogen b into another living organism
in_subset: eco subset

has vector
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

partner in
type: ObjectProperty
sub property of: participates in
term editor: https://orcid.org/0000-0002-6601-2165
curator note: Experimental: relation used for defining interaction relations. An interaction relation holds when there is an interaction event with two partners. In a directional interaction, one partner is deemed the subject, the other the target

subject participant in
type: ObjectProperty
sub property of: partner in
term editor: https://orcid.org/0000-0002-6601-2165
curator note: Experimental: relation used for defining interaction relations; the meaning of s 'subject participant in' p is determined by the type of p, where p must be a directional interaction process. For example, in a predator-prey interaction process the subject is the predator. We can imagine a reciprocal prey-predatory process with subject and object reversed.

target participant in
type: ObjectProperty
sub property of: partner in
term editor: https://orcid.org/0000-0002-6601-2165
curator note: Experimental: relation used for defining interaction relations; the meaning of s 'target participant in' p is determined by the type of p, where p must be a directional interaction process. For example, in a predator-prey interaction process the target is the prey. We can imagine a reciprocal prey-predatory process with subject and object reversed.

helper property (not for use in curation)
type: ObjectProperty
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning.
database_cross_reference: RO:0002464
shorthand: helper_property_(not_for_use_in_curation)

is symbiosis
type: ObjectProperty
sub property of: interaction relation helper property
term editor: https://orcid.org/0000-0002-6601-2165

is commensalism
type: ObjectProperty
sub property of: is symbiosis
term editor: https://orcid.org/0000-0002-6601-2165

is mutualism
type: ObjectProperty
sub property of: is symbiosis
term editor: https://orcid.org/0000-0002-6601-2165

is parasitism
type: ObjectProperty
sub property of: is symbiosis
term editor: https://orcid.org/0000-0002-6601-2165

provides nutrients for
type: ObjectProperty
sub property of: trophically interacts with
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
in_subset: eco subset

eats
type: ObjectProperty
sub property of: trophically interacts with
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: is subject of eating interaction with
in_subset: eco subset

is eaten by
type: ObjectProperty
sub property of: trophically interacts with
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: eaten by
alternative term: is target of eating interaction with
in_subset: eco subset

is evidence for
type: ObjectProperty
sub property of: related via evidence or inference to
inverse of: has evidence
definition: A relationship between a piece of evidence a and some entity b, where b is an information content entity, material entity or process, and the a supports either the existence of b, or the truth value of b.
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

composed primarily of
type: ObjectProperty
sub property of: has part
domain: material entity
range: material entity
example of usage: 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'
definition: x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
temporal interpretation: RO_0001901
database_cross_reference: RO:0002473
has_obo_namespace: uberon
id: composed_primarily_of
in_subset: eco subset
shorthand: composed_primarily_of

child nucleus of
type: ObjectProperty
sub property of: developmentally_preceded_by
domain: GO_0005634
range: GO_0005634
example of usage: ABal nucleus child nucleus of ABa nucleus (in C elegans)
definition: c is a child nucleus of d if and only if c and d are both nuclei and parts of cells c' and d', where c' is derived from d' by mitosis and the genetic material in c is a copy of the generic material in d
term editor: https://orcid.org/0000-0002-6601-2165
curator note: This relation is primarily used in the worm anatomy ontology for representing lineage at the level of nuclei. However, it is applicable to any organismal cell lineage.

child nucleus of in hermaphrodite
type: ObjectProperty
sub property of: child nucleus of
definition: A child nucleus relationship in which the cells are part of a hermaphroditic organism
term editor: https://orcid.org/0000-0002-6601-2165

child nucleus of in male
type: ObjectProperty
sub property of: child nucleus of
definition: A child nucleus relationship in which the cells are part of a male organism
term editor: https://orcid.org/0000-0002-6601-2165

has part that occurs in
type: ObjectProperty
domain: occurrent
range: independent continuant
property chain axiom: has part
property chain axiom: occurs in
definition: p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002479
in_subset: eco subset
shorthand: has_part_that_occurs_in

Axiom
annotated source: has part that occurs in
annotated property: propertyChainAxiom
annotated target: has part
annotated target: occurs in
is a defining property chain axiom: true

ubiquitinates
type: ObjectProperty
sub property of: molecularly interacts with
property chain axiom: capable of
property chain axiom: is ubiquitination
property chain axiom: has direct input
definition: An interaction relation between x and y in which x catalyzes a reaction in which one or more ubiquitin groups are added to y
editor note: Axiomatization to GO to be added later
term editor: https://orcid.org/0000-0002-6601-2165

is kinase activity
type: ObjectProperty
sub property of: molecular interaction relation helper property
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002481
shorthand: is_kinase_activity

is ubiquitination
type: ObjectProperty
sub property of: molecular interaction relation helper property
term editor: https://orcid.org/0000-0002-6601-2165

receives input from
type: ObjectProperty
sub property of: connected to
inverse of: sends output to
editor note: See notes for inverse relation
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002485
shorthand: receives_input_from

sends output to
type: ObjectProperty
sub property of: connected to
editor note: This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in.
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002486
shorthand: sends_output_to

relation between physical entity and a process or stage
type: ObjectProperty
domain: independent continuant
range: occurrent
term editor: https://orcid.org/0000-0002-6601-2165
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage.
database_cross_reference: RO:0002487
shorthand: relation_between_physical_entity_and_a_process_or_stage

existence starts during
type: ObjectProperty
sub property of: existence overlaps
sub property of: existence starts during or after
property chain axiom: part of
property chain axiom: existence starts at end of
definition: x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y).
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002488
has_obo_namespace: uberon
id: existence_starts_during
shorthand: existence_starts_during

existence starts with
type: ObjectProperty
sub property of: existence starts during
definition: x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y).
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002489
has_obo_namespace: uberon
id: existence_starts_with
shorthand: existence_starts_with

existence overlaps
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
definition: x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002490
shorthand: existence_overlaps
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence starts and ends during
type: ObjectProperty
sub property of: existence starts during
sub property of: existence ends during
definition: x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002491
has_exact_synonym: exists during
has_obo_namespace: uberon
id: existence_starts_and_ends_during
shorthand: existence_starts_and_ends_during
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends during
type: ObjectProperty
sub property of: existence overlaps
sub property of: existence ends during or before
property chain axiom: part of
property chain axiom: existence ends at start of
definition: Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely.
definition: x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y).
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002492
has_exact_synonym: ceases_to_exist_during
has_obo_namespace: uberon
id: existence_ends_during
shorthand: existence_ends_during
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

Axiom
annotated source: existence ends during
annotated property: definition
annotated target: Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

existence ends with
type: ObjectProperty
sub property of: existence ends during
definition: x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y).
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002493
has_obo_namespace: uberon
id: existence_ends_with
shorthand: existence_ends_with
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

transformation of
type: ObjectProperty
sub property of: develops from
type: TransitiveProperty
definition: x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002494
has_obo_namespace: uberon
id: transformation_of
shorthand: transformation_of

immediate transformation of
type: ObjectProperty
sub property of: directly develops from
sub property of: transformation of
definition: x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
is direct form of: transformation of
database_cross_reference: RO:0002495
has_obo_namespace: uberon
id: immediate_transformation_of
shorthand: immediate_transformation_of

existence starts during or after
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
property chain axiom: part of
property chain axiom: developmentally_preceded_by
property chain axiom: preceded by
property chain axiom: simultaneous with
property chain axiom: existence starts at end of
property chain axiom:
  inverse of: existence starts at end of
definition: x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y).
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002496
has_obo_namespace: uberon
id: existence_starts_during_or_after
shorthand: existence_starts_during_or_after
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

existence ends during or before
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
property chain axiom: part of
property chain axiom: developmentally succeeded by
property chain axiom: precedes
property chain axiom: simultaneous with
property chain axiom: existence ends at start of
property chain axiom:
  inverse of: existence ends at start of
definition: x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002497
has_obo_namespace: uberon
id: existence_ends_during_or_before
shorthand: existence_ends_during_or_before
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

causal agent in process
type: ObjectProperty
sub property of: causal relation between material entity and a process
inverse of: process has causal agent
definition: A relationship between a material entity and a process where the material entity has some causal role that influences the process
definition source: causal-relations
database_cross_reference: RO:0002500
shorthand: causal_agent_in_process

causal relation between processes
type: ObjectProperty
sub property of: causally related to
domain: occurrent
range: occurrent
definition: p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
database_cross_reference: RO:0002501
shorthand: causal_relation_between_processes

depends on
type: ObjectProperty
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002502
shorthand: depends_on

towards
type: ObjectProperty
sub property of: depends on
definition: q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2
editor note: This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20064205

has intermediate
type: ObjectProperty
sub property of: has participant
example of usage: 'lysine biosynthetic process via diaminopimelate' SubClassOf has_intermediate some diaminopimelate
definition: p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: has intermediate product
in_subset: eco subset

causal relation between entities
type: ObjectProperty
sub property of: causally related to
domain: continuant
range: continuant
editor note: The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
database_cross_reference: RO:0002506
shorthand: causal_relation_between_entities

determined by
type: ObjectProperty
sub property of: part of
sub property of: determined by part of
sub property of: causally influenced by
inverse of: determines
domain: RO_0002577
range: material entity
example of usage: A coral reef environment is determined by a particular coral reef
definition: s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s.
editor note: The label for this relation is probably too general for its restricted use, where the domain is a system. It may be relabeled in future
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/24330602
OBO foundry unique label: determined by (system to material entity)
creator: https://orcid.org/0000-0002-4366-3088
creator: https://orcid.org/0000-0002-6601-2165
creator: Chris Mungall
creator: Pier Buttigieg
in_subset: eco subset

determines
type: ObjectProperty
sub property of: causally influences
definition: inverse of determined by
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
OBO foundry unique label: determines (material entity to system)
in_subset: defined by inverse
in_subset: eco subset

determined by part of
type: ObjectProperty
sub property of: overlaps
sub property of: causal relation between entities
domain: RO_0002577
range: material entity
property chain axiom: determined by
property chain axiom: part of
definition: s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
in_subset: eco subset

Axiom
annotated source: determined by part of
annotated property: propertyChainAxiom
annotated target: determined by
annotated target: part of
RO_0002582: true

transcribed from
type: ObjectProperty
sub property of: genomically related to
inverse of: transcribed to
domain: Class
  union of: generically dependent continuant
  union of: material entity
range: Class
  union of: generically dependent continuant
  union of: material entity
definition: x is transcribed from y if and only if x is synthesized from template y
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267

transcribed to
type: ObjectProperty
sub property of: genomically related to
definition: inverse of transcribed from
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
in_subset: defined by inverse

ribosomal translation of
type: ObjectProperty
sub property of: genomically related to
inverse of: ribosomally translates to
domain: Class
  union of: generically dependent continuant
  union of: material entity
range: Class
  union of: generically dependent continuant
  union of: material entity
definition: x is the ribosomal translation of y if and only if a ribosome reads x through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces y
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267

ribosomally translates to
type: ObjectProperty
sub property of: genomically related to
domain: Class
  union of: generically dependent continuant
  union of: material entity
range: Class
  union of: generically dependent continuant
  union of: material entity
definition: inverse of ribosomal translation of
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267

sequentially related to
type: ObjectProperty
domain: RO_0002532
range: RO_0002532
definition: A relation that holds between two entities that have the property of being sequences or having sequences.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving cause and effect.
curator note: The domain and range of this relation include entities such as: information-bearing macromolecules such as DNA, or regions of these molecules; abstract information entities encoded as a linear sequence including text, abstract DNA sequences; Sequence features, entities that have a sequence or sequences. Note that these entities are not necessarily contiguous - for example, the mereological sum of exons on a genome of a particular gene.
cites as authority: 006650.abstract

sequentially adjacent to
type: ObjectProperty
sub property of: does not overlap sequence of
example of usage: Every UTR is adjacent to a CDS of the same transcript
example of usage: Two consecutive DNA residues are sequentially adjacent
example of usage: Two exons on a processed transcript that were previously connected by an intron are adjacent
definition: x is sequentially adjacent to y iff x and y do not overlap and if there are no base units intervening between x and y
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
cites as authority: 006650.abstract

has start sequence
type: ObjectProperty
sub property of: has subsequence
inverse of: is start sequence of
type: TransitiveProperty
example of usage: Every CDS has as a start sequence the start codon for that transcript
definition: x has start sequence y if the start of x is identical to the start of y, and x has y as a subsequence
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: started by
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
cites as authority: 006650.abstract

is start sequence of
type: ObjectProperty
sub property of: is subsequence of
type: TransitiveProperty
definition: inverse of has start sequence
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: starts
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
cites as authority: 006650.abstract
in_subset: defined by inverse

has end sequence
type: ObjectProperty
sub property of: has subsequence
inverse of: is end sequence of
type: TransitiveProperty
example of usage: Every CDS has as an end sequence the stop codon for that transcript (note this follows from the SO definition of CDS, in which stop codons are included)
definition: x has end sequence y if the end of x is identical to the end of y, and x has y as a subsequence
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: ended by
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
cites as authority: 006650.abstract

is end sequence of
type: ObjectProperty
sub property of: is subsequence of
type: TransitiveProperty
definition: inverse of has end sequence
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: ends
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
cites as authority: 006650.abstract
in_subset: defined by inverse

is consecutive sequence of
type: ObjectProperty
sub property of: has subsequence
definition: x is a consecutive sequence of y iff x has subsequence y, and all the parts of x are made of zero or more repetitions of y or sequences as the same type as y.
editor note: In the SO paper, this was defined as an instance-type relation
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
cites as authority: 006650.abstract

is sequentially aligned with
type: ObjectProperty
sub property of: sequentially related to
type: SymmetricProperty
example of usage: Human Shh and Mouse Shh are sequentially aligned, by cirtue of the fact that they derive from the same ancestral sequence.
definition: x is sequentially aligned with if a significant portion bases of x and y correspond in terms of their base type and their relative ordering
term editor: https://orcid.org/0000-0002-6601-2165
cites as authority: 006650.abstract

bounds sequence of
type: ObjectProperty
sub property of: sequentially related to
inverse of: is bound by sequence of
type: TransitiveProperty
example of usage: The genomic exons of a transcript bound the sequence of the genomic introns of the same transcript (but the introns are not subsequences of the exons)
definition: x bounds the sequence of y iff the upstream-most part of x is upstream of or coincident with the upstream-most part of y, and the downstream-most part of x is downstream of or coincident with the downstream-most part of y
term editor: https://orcid.org/0000-0002-6601-2165
cites as authority: 006650.abstract

is bound by sequence of
type: ObjectProperty
sub property of: sequentially related to
type: TransitiveProperty
definition: inverse of bounds sequence of
term editor: https://orcid.org/0000-0002-6601-2165
cites as authority: 006650.abstract
in_subset: defined by inverse

has subsequence
type: ObjectProperty
sub property of: has part
sub property of: bounds sequence of
sub property of: overlaps sequence of
inverse of: is subsequence of
type: TransitiveProperty
definition: x has subsequence y iff all of the sequence parts of y are sequence parts of x
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: contains
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20226267
cites as authority: 006650.abstract

is subsequence of
type: ObjectProperty
sub property of: part of
sub property of: is bound by sequence of
sub property of: overlaps sequence of
type: TransitiveProperty
definition: inverse of has subsequence
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: contained by
cites as authority: 006650.abstract
in_subset: defined by inverse

overlaps sequence of
type: ObjectProperty
sub property of: overlaps
sub property of: sequentially related to
type: SymmetricProperty
property chain axiom: has subsequence
property chain axiom: is subsequence of
definition: x overlaps the sequence of y if and only if x has a subsequence z and z is a subsequence of y.
term editor: https://orcid.org/0000-0002-6601-2165
cites as authority: 006650.abstract

does not overlap sequence of
type: ObjectProperty
sub property of: sequentially related to
type: SymmetricProperty
definition: x does not overlap the sequence of y if and only if there is no z such that x has a subsequence z and z is a subsequence of y.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: disconnected from
cites as authority: 006650.abstract

is upstream of sequence of
type: ObjectProperty
sub property of: does not overlap sequence of
type: TransitiveProperty
definition: inverse of downstream of sequence of
term editor: https://orcid.org/0000-0002-6601-2165
cites as authority: 006650.abstract

is downstream of sequence of
type: ObjectProperty
sub property of: does not overlap sequence of
type: TransitiveProperty
definition: x is downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, or (2) x and y are sequence units, and x is either immediately downstream of y, or transitively downstream of y.
term editor: https://orcid.org/0000-0002-6601-2165
cites as authority: 006650.abstract

is immediately downstream of sequence of
type: ObjectProperty
sub property of: sequentially adjacent to
sub property of: is downstream of sequence of
example of usage: A 3'UTR is immediately downstream of the sequence of the CDS from the same monocistronic transcript
definition: x is immediately downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, and x is sequentially adjacent to y, or (2) x and y are sequence units, in which case the immediately downstream relation is primitive and defined by context: for DNA bases, y would be adjacent and 5' to y
term editor: https://orcid.org/0000-0002-6601-2165
is direct form of: is downstream of sequence of
cites as authority: 006650.abstract

is immediately upstream of sequence of
type: ObjectProperty
sub property of: sequentially adjacent to
sub property of: is upstream of sequence of
example of usage: A 5'UTR is immediately upstream of the sequence of the CDS from the same monocistronic transcript
definition: inverse of immediately downstream of
term editor: https://orcid.org/0000-0002-6601-2165
cites as authority: 006650.abstract

has skeleton
type: ObjectProperty
sub property of: has part
inverse of: skeleton of
type: AsymmetricProperty
type: IrreflexiveProperty
domain: UBERON_0000061
domain: UBERON_0000475
range: UBERON_0000465
range: UBERON_0010912
example of usage: Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'
definition: A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision.
term editor: https://orcid.org/0000-0002-6601-2165
alternative term: has supporting framework
curator note: The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell).
database_cross_reference: RO:0002551
has_obo_namespace: uberon
id: has_skeleton
shorthand: has_skeleton

Axiom
annotated source: has skeleton
annotated property: range
annotated target: UBERON_0000465
editor note: This should be to a more restricted class, but not the Uberon class may be too restricted since it is a composition-based definition of skeleton rather than functional.

results in ending of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
definition: p results in the end of s if p results in a change of state in s whereby s either ceases to exist, or s becomes functionally impaired or s has its fate committed such that it is put on a path to be degraded.
term editor: https://orcid.org/0000-0002-6601-2165

hyperparasite of
type: ObjectProperty
sub property of: has host
inverse of: hyperparasitized by
property chain axiom: parasite of
definition: x is a hyperparasite of y iff x is a parasite of a parasite of the target organism y
editor note: Note that parasite-of is a diret relationship, so hyperparasite-of is not considered a sub-relation, even though hyperparasitism can be considered a form of parasitism
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://eol.org/schema/terms/hyperparasitoidOf
definition source: https://en.wikipedia.org/wiki/Hyperparasite
has_narrow_synonym: hyperparasitoid of
has_related_synonym: epiparasite of
in_subset: eco subset

hyperparasitized by
type: ObjectProperty
sub property of: host of
property chain axiom: parasitized by
definition: inverse of hyperparasite of
term editor: https://orcid.org/0000-0002-6601-2165
has_related_synonym: has epiparasite
has_related_synonym: has hyperparasite
has_related_synonym: hyperparasitoidized by
in_subset: defined by inverse
in_subset: eco subset

allelopath of
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://en.wikipedia.org/wiki/Allelopathy
in_subset: eco subset
see also: x is an allelopath of y iff xis an organism produces one or more biochemicals that influence the growth, survival, and reproduction of y

pathogen of
type: ObjectProperty
sub property of: has host
inverse of: has pathogen
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

has pathogen
type: ObjectProperty
sub property of: host of
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: eco subset

has evidence
type: ObjectProperty
sub property of: related via evidence or inference to
definition: inverse of is evidence for
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/25052702
in_subset: defined by inverse
in_subset: eco subset
comment: x has evidence y iff , x is an information content entity, material entity or process, and y supports either the existence of x, or the truth value of x.

causally influenced by
type: ObjectProperty
sub property of: causal relation between entities
inverse of: causally influences
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
OBO foundry unique label: causally influenced by (entity-centric)
database_cross_reference: RO:0002559
shorthand: causally_influenced_by

interaction relation helper property
type: ObjectProperty
sub property of: helper property (not for use in curation)
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002563
shorthand: interaction_relation_helper_property

molecular interaction relation helper property
type: ObjectProperty
sub property of: interaction relation helper property
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002564
shorthand: molecular_interaction_relation_helper_property

results in movement of
type: ObjectProperty
sub property of: results in changes to anatomical or cellular structure
definition: Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c
term editor: https://orcid.org/0000-0002-6601-2165
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam

causally influences
type: ObjectProperty
sub property of: causal relation between entities
domain: continuant
range: continuant
property chain axiom: enables
property chain axiom: causally upstream of
property chain axiom: has input
property chain axiom: enabled by
definition: The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
term editor: https://orcid.org/0000-0002-6601-2165
term editor: https://orcid.org/0000-0003-4639-4431
term editor: Chris Mungall
term editor: Vasundra Touré
definition source: causal-relations
OBO foundry unique label: causally influences (entity-centric)
database_cross_reference: RO:0002566
shorthand: causally_influences

biomechanically related to
type: ObjectProperty
sub property of: functionally related to
domain: UBERON_0000061
range: UBERON_0000061
definition: A relation that holds between elements of a musculoskeletal system or its analogs.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes.
database_cross_reference: RO:0002567
shorthand: biomechanically_related_to

has muscle antagonist
type: ObjectProperty
sub property of: biomechanically related to
definition: m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: Wikipedia:Antagonist_(muscle)
database_cross_reference: RO:0002568
has_obo_namespace: uberon
id: has_muscle_antagonist
shorthand: has_muscle_antagonist

has branching part
type: ObjectProperty
sub property of: has part
sub property of: in branching relationship with
type: TransitiveProperty
definition: inverse of branching part of
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002569
has_obo_namespace: uberon
id: has_branching_part
in_subset: defined by inverse
in_subset: eco subset
shorthand: has_branching_part

conduit for
type: ObjectProperty
sub property of: overlaps
domain: material entity
range: material entity
definition: x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: UBERON:cjm
curator note: This relation holds between a thing with a 'conduit' (e.g. a bone foramen) and a 'conduee' (for example, a nerve) such that at the time the relationship holds, the conduee has two ends sticking out either end of the conduit. It should therefore note be used for objects that move through the conduit but whose spatial extent does not span the passage. For example, it would not be used for a mountain that contains a long tunnel through which trains pass. Nor would we use it for a digestive tract and objects such as food that pass through.
database_cross_reference: RO:0002570
has_obo_namespace: uberon
id: conduit_for
in_subset: eco subset
shorthand: conduit_for

lumen of
type: ObjectProperty
sub property of: part of
range: material entity
definition: x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002571
has_obo_namespace: uberon
id: lumen_of
in_subset: eco subset
shorthand: lumen_of

luminal space of
type: ObjectProperty
sub property of: lumen of
domain: immaterial entity
definition: s is luminal space of x iff s is lumen_of x and s is an immaterial entity
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002572
has_obo_namespace: uberon
id: luminal_space_of
in_subset: eco subset
shorthand: luminal_space_of

has modifier
type: ObjectProperty
domain: characteristic
range: characteristic
definition: A relation that holds between an attribute or a qualifier and another attribute.
term editor: https://orcid.org/0000-0002-6601-2165
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20064205
curator note: This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the "modifiers" are.
in_subset: eco subset

participates in a biotic-biotic interaction with
type: ObjectProperty
sub property of: biotically interacts with
domain: OBI_0100026
range: OBI_0100026
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
in_subset: eco subset

skeleton of
type: ObjectProperty
sub property of: part of
domain: UBERON_0000061
range: UBERON_0000061
definition: inverse of has skeleton
term editor: https://orcid.org/0000-0002-6601-2165
database_cross_reference: RO:0002576
has_obo_namespace: uberon
id: skeleton_of
in_subset: defined by inverse
shorthand: skeleton_of

directly regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: immediately causally upstream of
definition: p directly regulates q iff p is immediately causally upstream of q and p regulates q.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
OBO foundry unique label: directly regulates (processual)
is direct form of: regulates (processual)
database_cross_reference: RO:0002578
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: directly_regulates

existence starts at end of
type: ObjectProperty
sub property of: existence starts during or after
definition: holds between x and y if and only if the time point at which x starts is equivalent to the time point at which y ends. Formally: iff α(x) = ω(y).

has part structure that is capable of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal relation between material entity and a process
property chain axiom: has part
property chain axiom: capable of
example of usage: gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
definition: s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
database_cross_reference: RO:0002584
shorthand: has_part_structure_that_is_capable_of

results in closure of
type: ObjectProperty
sub property of: results in developmental progression of
sub property of: results in changes to anatomical or cellular structure
editor note: p 'results in closure of' c if and only if p is a developmental process and p results in a state of c changing from open to closed.

results in breakdown of
type: ObjectProperty
sub property of: has input
definition: p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p
database_cross_reference: RO:0002586
shorthand: results_in_breakdown_of

results in synthesis of
type: ObjectProperty
sub property of: results in formation of

results in assembly of
type: ObjectProperty
sub property of: results in formation of
sub property of: results in organization of
database_cross_reference: RO:0002588
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: results_in_assembly_of

results in catabolism of
type: ObjectProperty
sub property of: results in breakdown of
definition: p results in catabolism of c if and only if p is a catabolic process, and the execution of p results in c being broken into smaller parts with energy being released.

results in disassembly of
type: ObjectProperty
sub property of: results in breakdown of
sub property of: results in organization of
database_cross_reference: RO:0002590
shorthand: results_in_disassembly_of

results in remodeling of
type: ObjectProperty
sub property of: has input
sub property of: results in organization of

results in organization of
type: ObjectProperty
sub property of: results in changes to anatomical or cellular structure
definition: p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c
database_cross_reference: RO:0002592
shorthand: results_in_organization_of

existence ends at start of
type: ObjectProperty
sub property of: existence ends during or before
definition: holds between x and y if and only if the time point at which x ends is equivalent to the time point at which y starts. Formally: iff ω(x) = α(y).

causal relation between material entity and a process
type: ObjectProperty
sub property of: causally related to
domain: material entity
range: process
definition: A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
editor note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
term editor: https://orcid.org/0000-0002-6601-2165
term editor: Chris Mungall
definition source: causal-relations
database_cross_reference: RO:0002595
shorthand: causal_relation_between_material_entity_and_a_process

capable of regulating
type: ObjectProperty
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: regulates (processual)
example of usage: pyrethroid -> growth
definition: Holds between c and p if and only if c is capable of some activity a, and a regulates p.
definition source: causal-relations
database_cross_reference: RO:0002596
shorthand: capable_of_regulating

capable of negatively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: negatively regulates
definition: Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
definition source: causal-relations
database_cross_reference: RO:0002597
shorthand: capable_of_negatively_regulating

capable of positively regulating
type: ObjectProperty
sub property of: capable of regulating
property chain axiom: capable of
property chain axiom: positively regulates
example of usage: renin -> arteriolar smooth muscle contraction
definition: Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
definition source: causal-relations
database_cross_reference: RO:0002598
shorthand: capable_of_positively_regulating

capable of inhibiting or preventing pathological process
type: ObjectProperty
sub property of: capable of negatively regulating
example of usage: pazopanib -> pathological angiogenesis
definition: Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p.
alternative term: treats
definition source: causal-relations
curator note: The entity c may be a molecular entity with a drug role, or it could be some other entity used in a therapeutic context, such as a hyperbaric chamber.

Axiom
annotated source: capable of inhibiting or preventing pathological process
annotated property: alternative term
annotated target: treats
comment: Usage of the term 'treats' applies when we believe there to be a an inhibitory relationship

capable of upregulating or causing pathological process
type: ObjectProperty
sub property of: capable of positively regulating
example of usage: benzene -> cancer [CHEBI]
definition: Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a negatively regulates p.
alternative term: causes disease
definition source: causal-relations

is substance that treats
type: ObjectProperty
sub property of: capable of inhibiting or preventing pathological process
definition: c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d.
alternative term: treats
definition source: causal-relations

is marker for
type: ObjectProperty
sub property of: correlated with
definition: c is marker for d iff the presence or occurrence of d is correlated with the presence of occurrence of c, and the observation of c is used to infer the presence or occurrence of d. Note that this does not imply that c and d are in a direct causal relationship, as it may be the case that there is a third entity e that stands in a direct causal relationship with c and d.
editor note: May be ceded to OBI

process has causal agent
type: ObjectProperty
sub property of: causally related to
definition: Inverse of 'causal agent in process'
definition source: causal-relations
database_cross_reference: RO:0002608
shorthand: process_has_causal_agent

correlated with
type: ObjectProperty
definition: A relationship that holds between two entities, where the entities exhibit a statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.
curator note: Groups both positive and negative correlation

is evidence with support from
type: ObjectProperty
sub property of: related via evidence or inference to
example of usage: An instance of a sequence similarity evidence (ECO:0000044) that uses a homologous sequence UniProtKB:P12345 as support.
definition: A relationship between a piece of evidence and an entity that plays a role in supporting that evidence.
comment: In the Gene Ontology association model, this corresponds to the With/From field

has model
type: ObjectProperty
inverse of: has role in modeling
definition: Inverse of is-model-of

related via evidence or inference to
type: ObjectProperty
curator note: Do not use this relation directly. It is a grouping relation.

visits
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with
inverse of: visited by

visited by
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with

visits flowers of
type: ObjectProperty
sub property of: visits
inverse of: has flowers visited by

has flowers visited by
type: ObjectProperty
sub property of: visited by

lays eggs in
type: ObjectProperty
sub property of: parasite of
sub property of: visits
inverse of: has eggs laid in by

has eggs laid in by
type: ObjectProperty
sub property of: parasitized by
sub property of: visited by

kills
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with
inverse of: is killed by
definition source: https://github.com/jhpoelen/eol-globi-data/issues/143

is killed by
type: ObjectProperty
sub property of: participates in a biotic-biotic interaction with

directly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: directly regulates
definition: p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.
definition source: causal-relations
OBO foundry unique label: directly positively regulates (process to process)
is positive form of: directly regulates
database_cross_reference: RO:0002629
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: directly_positively_regulates

directly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: directly regulates
definition: p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.
definition source: causal-relations
OBO foundry unique label: directly negatively regulates (process to process)
is negative form of: directly regulates
database_cross_reference: RO:0002630
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: directly_negatively_regulates

ectoparasite of
type: ObjectProperty
sub property of: parasite of
inverse of: has ectoparasite
definition: A sub-relation of parasite-of in which the parasite lives on or in the integumental system of the host
definition source: Types

has ectoparasite
type: ObjectProperty
sub property of: parasitized by
definition: inverse of ectoparasite of
in_subset: defined by inverse

endoparasite of
type: ObjectProperty
sub property of: parasite of
inverse of: has endoparasite
definition source: Types
definition source: A sub-relation of parasite-of in which the parasite lives inside the host, beneath the integumental system
has_related_synonym: lives inside of

has endoparasite
type: ObjectProperty
sub property of: parasitized by

mesoparasite of
type: ObjectProperty
sub property of: parasite of
inverse of: has mesoparasite
definition: A sub-relation of parasite-of in which the parasite is partially an endoparasite and partially an ectoparasite

has mesoparasite
type: ObjectProperty
sub property of: parasitized by
definition: inverse of mesoparasite of
in_subset: defined by inverse

intercellular endoparasite of
type: ObjectProperty
sub property of: endoparasite of
inverse of: has intercellular endoparasite
definition: A sub-relation of endoparasite-of in which the parasite inhabits the spaces between host cells.
definition source: Types

has intercellular endoparasite
type: ObjectProperty
sub property of: has endoparasite
definition: inverse of intercellular endoparasite of
in_subset: defined by inverse

intracellular endoparasite of
type: ObjectProperty
sub property of: endoparasite of
inverse of: has intracellular endoparasite
definition: A sub-relation of endoparasite-of in which the parasite inhabits host cells.
definition source: Types

has intracellular endoparasite
type: ObjectProperty
sub property of: has endoparasite
definition: inverse of intracellular endoparasite of
in_subset: defined by inverse

co-roosts with
type: ObjectProperty
sub property of: ecologically co-occurs with
type: SymmetricProperty
definition: Two or more individuals sharing the same roost site (cave, mine, tree or tree hollow, animal burrow, leaf tent, rock crack, space in man-made structure, etc.). Individuals that are sharing a communal roost may be said to be co-roosting. The roost may be either a day roost where the individuals rest during daytime hours, or a night roost where individuals roost to feed, groom, or rest in between flights and/or foraging bouts. Communal roosting as thus defined is an umbrella term within which different specialized types -- which are not mutually exclusive -- may be recognized based on taxonomy and the temporal and spatial relationships of the individuals that are co-roosting.
definition source: Communal roosting

reservoir host of
type: ObjectProperty
sub property of: host of
inverse of: has reservoir host
example of usage: An individual of species Camelus dromedarius (commonly known as dromedary camels) is a reservoir host of an individual of Middle East respiratory syndrome–related coronavirus (MERS-CoV) since at least the 1980s.
definition: A relation between a host organism and a hosted organism in which the hosted organism naturally occurs in an indefinitely maintained reservoir provided by the host.
definition source: v13071356
contributor: https://orcid.org/0000-0002-3120-4802
contributor: https://orcid.org/0000-0003-3138-4118
comment: A reservoir is a population, species or community (assemblage of different species in a given geographic area) in which a microorganism naturally occurs and is indefinitely maintained. Some zoonotic pathogens, particularly bacterial pathogens, may also have environmental reservoirs. Microorganisms with multiple reservoir species may be indefinitely maintained across the community of species even if they are not always present in each individual reservoir species. In the reservoir species or community, the microorganism may cause either asymptomatic infection or disease and this may vary among individuals. A pathogen may also be more genetically diverse in its reservoir host than in other taxa, in part because the pathogen is endemic to reservoir hosts.

has reservoir host
type: ObjectProperty
sub property of: has host
example of usage: An individual of Middle East respiratory syndrome–related coronavirus (MERS-CoV) has an individual of species Camelus dromedarius (commonly known as dromedary camels) as their reservoir host since at least the 1980s.
definition: inverse of reservoir host of
in_subset: defined by inverse

produces
type: ObjectProperty
inverse of: produced by
domain: material entity
range: material entity
property chain axiom:
  inverse of: occurs in
property chain axiom: has output
has curation status: IAO_0000125
definition: a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.
term editor: https://orcid.org/0000-0001-9114-8737
term editor: Melissa Haendel
database_cross_reference: RO:0003000
has_obo_namespace: uberon
id: produces
in_subset: eco subset
shorthand: produces
comment: Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue.

produced by
type: ObjectProperty
domain: material entity
range: material entity
has curation status: IAO_0000125
definition: a produced_by b iff some process that occurs_in b has_output a.
term editor: https://orcid.org/0000-0001-9114-8737
term editor: Melissa Haendel
database_cross_reference: RO:0003001
has_obo_namespace: uberon
id: produced_by
in_subset: eco subset
shorthand: produced_by

represses expression of
type: ObjectProperty
sub property of: directly negatively regulates activity of
domain: material entity
range: material entity
definition: Holds between entity A (a transcription factor) and a nucleic acid B if and only if A down-regulates the expression of B. The nucleic acid can be a gene or an mRNA.
term editor: https://orcid.org/0000-0003-4639-4431

increases expression of
type: ObjectProperty
sub property of: directly positively regulates activity of
domain: material entity
range: material entity
definition: Holds between entity A (a transcription factor) and nucleic acid B if and only if A up-regulates the expression of B. The nucleic acid can be a gene or mRNA.
term editor: https://orcid.org/0000-0003-4639-4431

has role in modeling
type: ObjectProperty
type: AsymmetricProperty
type: IrreflexiveProperty
definition: A relation between a biological, experimental, or computational artifact and an entity it is used to study, in virtue of its replicating or approximating features of the studied entity.
term editor: https://orcid.org/0000-0002-1048-5019
alternative term: is used to study
comment: The primary use case for this relation was to link a biological model system such as a cell line or model organism to a disease it is used to investigate, in virtue of the model system exhibiting features similar to that of the disease of interest. But the relation is defined more broadly to support other use cases, such as linking genes in which alterations are made to create model systems to the condition the system is used to interrogate, or computational models to real-world phenomena they are defined to simulate.

causes or contributes to condition
type: ObjectProperty
sub property of: causally related to
example of usage: The genetic variant 'NM_007294.3(BRCA1):c.110C>A (p.Thr37Lys)' casues or contributes to the disease 'familial breast-ovarian cancer'. An environment of exposure to arsenic causes or contributes to the phenotype of patchy skin hyperpigmentation, and the disease 'skin cancer'.
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal or contributing role that influences the condition.
editor note: Note that relationships of phenotypes to organisms/strains that bear them, or diseases they are manifest in, should continue to use RO:0002200 ! 'has phenotype' and RO:0002201 ! 'phenotype of'.
comment: Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to. Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions.

causes condition
type: ObjectProperty
sub property of: causes or contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition.

contributes to condition
type: ObjectProperty
sub property of: causes or contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition.

contributes to severity of condition
type: ObjectProperty
sub property of: contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the severity with which a condition manifests in an individual.
alternative term: contributes to expressivity of condition

contributes to frequency of condition
type: ObjectProperty
sub property of: contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the frequency of the condition in a population.
alternative term: contributes to penetrance of condition

ameliorates condition
type: ObjectProperty
sub property of: contributes to severity of condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition.
alternative term: is preventative for condition
comment: Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to. Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions.

correlated with condition
type: ObjectProperty
sub property of: correlated with
definition: A relationship between an entity and a condition (phenotype or disease) with which it exhibits a statistical dependence relationship.

exacerbates condition
type: ObjectProperty
sub property of: contributes to severity of condition
definition: A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition.

condition ameliorated by
type: ObjectProperty
sub property of: causally related to
definition: A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are reduced or eliminated by the presence of the entity.

condition exacerbated by
type: ObjectProperty
sub property of: causally related to
definition: A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are worsened by the presence of the entity.

condition has genetic basis in
type: ObjectProperty
sub property of: causally related to
inverse of: is genetic basis for condition
domain: realizable
range: Class
  union of: process
  union of: quality
  union of: material entity
curator note: Do not use this relation directly. It is intended as a grouping for a more specific relations
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:38:20Z

has material basis in gain of function germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
inverse of: is causal gain of function germline mutation of in
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:45:20Z

has material basis in loss of function germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
inverse of: is causal loss of function germline mutation of in
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:45:37Z

has material basis in germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
inverse of: is causal germline mutation in
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:45:54Z

has material basis in somatic mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
inverse of: is causal somatic mutation in
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:46:07Z

has major susceptibility factor
type: ObjectProperty
sub property of: condition has genetic basis in
inverse of: is causal susceptibility factor for
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:46:26Z

has partial material basis in germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
inverse of: is causal germline mutation partially giving rise to
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:46:57Z

has primary input or output
type: ObjectProperty
sub property of: has participant
definition: p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-12-13T11:26:17Z
database_cross_reference: RO:0004007
in_subset: valid_for_go_ontology
shorthand: has_primary_input_or_output

has primary output
type: ObjectProperty
sub property of: has output
sub property of: has primary input or output
definition: p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-12-13T11:26:32Z
database_cross_reference: RO:0004008
in_subset: valid_for_go_ontology
shorthand: has_primary_output

Axiom
annotated source: has primary output
annotated property: definition
annotated target: p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.
database_cross_reference: https://orcid.org/0000-0002-6601-2165
database_cross_reference: GOC:dph
database_cross_reference: GOC:kva
database_cross_reference: GOC:pt
comment: PMID:27812932

has primary input
type: ObjectProperty
sub property of: has input
sub property of: has primary input or output
definition: p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-12-13T11:26:56Z
database_cross_reference: RO:0004009
in_subset: valid_for_go_ontology
shorthand: has_primary_input

Axiom
annotated source: has primary input
annotated property: definition
annotated target: p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.
database_cross_reference: https://orcid.org/0000-0002-6601-2165
database_cross_reference: GOC:dph
database_cross_reference: GOC:kva
database_cross_reference: GOC:pt
comment: PMID:27812932

is genetic basis for condition
type: ObjectProperty
sub property of: is basis for realizable
range: realizable
curator note: Do not use this relation directly. It is intended as a grouping for a more specific relations
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:53:08Z

is causal gain of function germline mutation of in
type: ObjectProperty
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene in a germ cell provides a new function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:55:51Z

is causal loss of function germline mutation of in
type: ObjectProperty
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene in a germ cell impairs the function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:56:06Z

is causal germline mutation in
type: ObjectProperty
sub property of: causes condition
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:56:40Z

is causal somatic mutation in
type: ObjectProperty
sub property of: causes condition
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition but that cannot be passed on to offspring[modified from orphanet].
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:57:07Z

is causal susceptibility factor for
type: ObjectProperty
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene predisposes to the development of a condition and that is necessary but not sufficient to develop the condition[modified from orphanet].
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:57:43Z

is causal germline mutation partially giving rise to
type: ObjectProperty
sub property of: contributes to condition
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene partially contributes to the presentation of this condition[modified from orphanet].
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T02:58:43Z

realizable has basis in
type: ObjectProperty
sub property of: causally related to
inverse of: is basis for realizable
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:20:01Z

is basis for realizable
type: ObjectProperty
sub property of: causally related to
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:20:29Z

disease has basis in
type: ObjectProperty
sub property of: realizable has basis in
sub property of: causal relationship with disease as subject
domain: OGMS_0000031
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:26:47Z

disease has basis in dysfunction of
type: ObjectProperty
sub property of: disease has basis in
range: UBERON_0000465
definition: A relation that holds between the disease and a material entity where the physical basis of the disease is a disorder of that material entity that affects its function.
OBO foundry unique label: disease has basis in dysfunction of (disease to anatomical structure)
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:29:32Z

disease has basis in disruption of
type: ObjectProperty
sub property of: disease has basis in
range: process
definition: A relation that holds between the disease and a process where the physical basis of the disease disrupts execution of a key biological process.
OBO foundry unique label: disease has basis in disruption of (disease to process)
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:37:52Z

disease has basis in feature
type: ObjectProperty
sub property of: has phenotype
sub property of: disease has basis in
domain: OGMS_0000031
range: Class
  union of: OGMS_0000031
  union of: UPHENO_0001001
definition: A relation that holds between the disease and a feature (a phenotype or other disease) where the physical basis of the disease is the feature.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:46:07Z

causal relationship with disease as subject
type: ObjectProperty
sub property of: causally related to
sub property of: disease relationship
domain: OGMS_0000031
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all of which have a disease as the subject.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:50:54Z

disease causes disruption of
type: ObjectProperty
sub property of: causal relationship with disease as subject
domain: OGMS_0000031
range: process
property chain axiom: part of
property chain axiom: disease causes dysfunction of
property chain axiom: capable of
definition: A relationship between a disease and a process where the disease process disrupts the execution of the process.
OBO foundry unique label: disease causes disruption of (disease to process)
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:51:09Z

disease causes dysfunction of
type: ObjectProperty
sub property of: causal relationship with disease as subject
domain: OGMS_0000031
range: UBERON_0000465
property chain axiom: part of
OBO foundry unique label: disease causes dysfunction of (disease to anatomical entity)
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T03:58:20Z

disease has location
type: ObjectProperty
sub property of: disease relationship
domain: OGMS_0000031
range: independent continuant
range: Class
  union of: UBERON_0000465
  union of: UBERON_0000466
definition: A relationship between a disease and an anatomical entity where the disease has one or more features that are located in that entity.
editor note: TODO: complete range axiom once more of CARO has been mireoted in to this ontology
curator note: This relation is intentionally very general, and covers isolated diseases, where the disease is realized as a process occurring in the location, and syndromic diseases, where one or more of the features may be present in that location. Thus any given disease can have multiple locations in the sense defined here.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-11-05T04:06:02Z

disease has inflammation site
type: ObjectProperty
sub property of: disease has location
domain: OGMS_0000031
range: independent continuant
range: Class
  union of: UBERON_0000465
  union of: UBERON_0000466
definition: A relationship between a disease and an anatomical entity where the disease is triggered by an inflammatory response to stimuli occurring in the anatomical entity
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-12-26T19:37:31Z

realized in response to stimulus
type: ObjectProperty
sub property of: causally related to
domain: realizable
range: material entity
property chain axiom: realized in response to
property chain axiom: has input
definition: A relationship between a realizable entity R (e.g. function or disposition) and a material entity M where R is realized in response to a process that has an input stimulus of M.
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2017-12-26T19:45:49Z

disease has feature
type: ObjectProperty
sub property of: disease relationship
domain: OGMS_0000031
range: Class
  union of: OGMS_0000031
  union of: UPHENO_0001001
definition: A relationship between a disease and some feature of that disease, where the feature is either a phenotype or an isolated disease.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-12-26T19:50:53Z

disease arises from alteration in structure
type: ObjectProperty
sub property of: disease has basis in
range: UBERON_0000061
definition: A relationship between a disease and an anatomical structure where the material basis of the disease is some pathological change in the structure. Anatomical structure includes cellular and sub-cellular entities, such as chromosome and organelles.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2017-12-26T19:58:44Z

enables subfunction
type: ObjectProperty
sub property of: functionally related to
property chain axiom: enables
property chain axiom: has part
definition: Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2018-01-25T23:20:13Z
database_cross_reference: RO:0004031
shorthand: enables_subfunction

acts upstream of or within, positive effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, positive effect
is positive form of: acts upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2018-01-26T23:49:30Z
database_cross_reference: RO:0004032
in_subset: valid_for_go_gp2term
shorthand: acts_upstream_of_or_within,_positive_effect

acts upstream of or within, negative effect
type: ObjectProperty
sub property of: acts upstream of or within
property chain axiom: enables
property chain axiom: causally upstream of or within, negative effect
is negative form of: acts upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2018-01-26T23:49:51Z
database_cross_reference: RO:0004033
in_subset: valid_for_go_gp2term
shorthand: acts_upstream_of_or_within,_negative_effect

acts upstream of, positive effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, positive effect
property chain axiom: enables
property chain axiom: causally upstream of, positive effect
definition: c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
is positive form of: acts upstream of
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2018-01-26T23:53:14Z
database_cross_reference: RO:0004034
in_subset: valid_for_go_gp2term
shorthand: acts_upstream_of,_positive_effect

acts upstream of, negative effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, negative effect
property chain axiom: enables
property chain axiom: causally upstream of, negative effect
definition: c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
is negative form of: acts upstream of
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2018-01-26T23:53:22Z
database_cross_reference: RO:0004035
in_subset: valid_for_go_gp2term
shorthand: acts_upstream_of,_negative_effect

causally upstream of or within, negative effect
type: ObjectProperty
sub property of: causally upstream of or within
is negative form of: causally upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2018-03-13T23:55:05Z
database_cross_reference: RO:0004046
shorthand: causally_upstream_of_or_within,_negative_effect

causally upstream of or within, positive effect
type: ObjectProperty
sub property of: causally upstream of or within
is positive form of: causally upstream of or within
created by: https://orcid.org/0000-0002-6601-2165
created by: cjm
creation date: 2018-03-13T23:55:19Z
database_cross_reference: RO:0004047
shorthand: causally_upstream_of_or_within,_positive_effect

has driver
type: ObjectProperty
definition: A relation between two entities, in which one of the entities is any natural or human-influenced factor that directly or indirectly causes a change in the other entity.
contributor: https://orcid.org/0000-0001-8910-9851

has disease driver
type: ObjectProperty
sub property of: has driver
definition: A relation between an entity and a disease of a host, in which the entity is not part of the host itself, and the condition results in pathological processes.
contributor: https://orcid.org/0000-0001-8910-9851

epiphyte of
type: ObjectProperty
sub property of: symbiotically interacts with
inverse of: has epiphyte
definition: An interaction relationship wherein a plant or algae is living on the outside surface of another plant.
definition source: https://en.wikipedia.org/wiki/Epiphyte

has epiphyte
type: ObjectProperty
sub property of: symbiotically interacts with
definition: inverse of epiphyte of
in_subset: defined by inverse

kleptoparasite of
type: ObjectProperty
sub property of: parasite of
inverse of: kleptoparasitized by
definition: A sub-relation of parasite of in which a parasite steals resources from another organism, usually food or nest material
definition source: https://en.wikipedia.org/wiki/Kleptoparasitism

kleptoparasitized by
type: ObjectProperty
sub property of: parasitized by
definition: inverse of kleptoparasite of
in_subset: defined by inverse

creates habitat for
type: ObjectProperty
sub property of: ecologically related to
domain: OBI_0100026
range: OBI_0100026
definition: An interaction relationship wherein one organism creates a structure or environment that is lived in by another organism.

ecologically co-occurs with
type: ObjectProperty
sub property of: ecologically related to
type: SymmetricProperty
domain: OBI_0100026
range: OBI_0100026
definition: An interaction relationship describing organisms that often occur together at the same time and space or in the same environment.

lays eggs on
type: ObjectProperty
sub property of: visits
inverse of: has eggs laid on by
definition: An interaction relationship in which organism a lays eggs on the outside surface of organism b. Organism b is neither helped nor harmed in the process of egg laying or incubation.

has eggs laid on by
type: ObjectProperty
sub property of: visited by
definition: inverse of lays eggs on

has roost
type: ObjectProperty
sub property of: has habitat
domain: OBI_0100026
range: ENVO_01000739
example of usage: Flying foxes (Pteropus giganteus) has_roost banyan tree (Ficus benghalensis)
definition: x 'has roost' y if and only if: x is an organism, y is a habitat, and y can support rest behaviors x.
contributor: https://orcid.org/0000-0002-2908-3327
date: 2023-01-18T14:28:21Z
in_subset: eco subset
comment: A population of xs will possess adaptations (either evolved naturally or via artifical selection) which permit it to rest in y.

has substance added
type: ObjectProperty
type: IrreflexiveProperty
domain: material entity
range: material entity
example of usage: muffin 'has substance added' some 'baking soda'
has curation status: IAO_0000428
definition: "has substance added" is a relation existing between a (physical) entity and a substance in which the entity has had the substance added to it at some point in time.
editor note: The relation X 'has substance added' some Y doesn't imply that X still has Y in any detectable fashion subsequent to the addition. Water in dehydrated food or ice cubes are examples, as is food that undergoes chemical transformation. This definition should encompass recipe ingredients.
term editor: https://orcid.org/0000-0002-8844-9165
term editor: Damion Dooley

has substance removed
type: ObjectProperty
type: IrreflexiveProperty
domain: material entity
range: material entity
example of usage: 'egg white' 'has substance removed' some 'egg yolk'
has curation status: IAO_0000428
definition: "has substance removed" is a relation existing between two physical entities in which the first entity has had the second entity (a substance) removed from it at some point in time.
term editor: https://orcid.org/0000-0002-8844-9165

immersed in
type: ObjectProperty
type: IrreflexiveProperty
domain: material entity
range: material entity
example of usage: sardines 'immersed in' some 'oil and mustard'
has curation status: IAO_0000428
definition: "immersed in" is a relation between a (physical) entity and a fluid substance in which the entity is wholely or substantially surrounded by the substance.
term editor: https://orcid.org/0000-0002-8844-9165

has consumer
type: ObjectProperty
domain: material entity
range: OBI_0100026
example of usage: sardine has consumer some homo sapiens
has curation status: IAO_0000428
definition: 'has consumer' is a relation between a material entity and an organism in which the former can normally be digested or otherwise absorbed by the latter without immediate or persistent ill effect.
term editor: https://orcid.org/0000-0002-8844-9165

has primary substance added
type: ObjectProperty
sub property of: has substance added
type: IrreflexiveProperty
example of usage: bread 'has primary substance added' some 'flour'
has curation status: IAO_0000428
definition: 'has primary substance added' indicates that an entity has had the given substance added to it in a proportion greater than any other added substance.
term editor: https://orcid.org/0000-0002-8844-9165

realized in response to
type: ObjectProperty
sub property of: causally related to
domain: realizable
range: process
property chain axiom: realized in
property chain axiom: causally downstream of
example of usage: A drought sensitivity trait that inheres in a whole plant is realized in a systemic response process in response to exposure to drought conditions.
example of usage: An inflammatory disease that is realized in response to an inflammatory process occurring in the gut (which is itself the realization of a process realized in response to harmful stimuli in the mucosal lining of th gut)
example of usage: Environmental polymorphism in butterflies: These butterflies have a 'responsivity to day length trait' that is realized in response to the duration of the day, and is realized in developmental processes that lead to increased or decreased pigmentation in the adult morph.
definition: r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r.
contributor: https://orcid.org/0000-0001-6996-0040
contributor: https://orcid.org/0000-0002-6601-2165
contributor: https://orcid.org/0000-0002-7073-9172
contributor: https://orcid.org/0000-0002-8461-9745
contributor: Austin Meier
contributor: Chris Mungall
contributor: David Osumi-Sutherland
contributor: Marie Angelique Laporte
has_exact_synonym: triggered by process

Axiom
annotated source: realized in response to
annotated property: has_exact_synonym
annotated target: triggered by process
database_cross_reference: https://orcid.org/0000-0002-6601-2165

Axiom
annotated source: realized in response to
annotated property: has_exact_synonym
annotated target: triggered by process
database_cross_reference: RO:cjm

generically depends on
type: ObjectProperty
inverse of: is carrier of
domain: generically dependent continuant
range: independent continuant
property chain axiom: characteristic of
property chain axiom: is concretized as
example of usage: Genetic information generically depend on molecules of DNA.
example of usage: The novel *War and Peace* generically depends on this copy of the novel.
example of usage: The pattern shared by chess boards generically depends on any chess board.
example of usage: The score of a symphony g-depends on a copy of the score.
example of usage: This pdf file generically depends on this server.
definition: A generically dependent continuant *b* generically depends on an independent continuant *c* at time *t* means: there inheres in *c* a specifically deendent continuant which concretizes *b* at *t*.
definition source: [072-ISO]
has_exact_synonym: g-depends on

is carrier of
type: ObjectProperty
domain: independent continuant
range: generically dependent continuant
property chain axiom: concretizes
property chain axiom: has characteristic
example of usage: Molecules of DNA are carriers of genetic information.
example of usage: This copy of *War and Peace* is carrier of the novel written by Tolstoy.
example of usage: This hard drive is carrier of these data items.
definition: *b* is carrier of *c* at time *t* if and only if *c* *g-depends on* *b* at *t*
definition source: [072-ISO]

regulates activity of
type: ObjectProperty
sub property of: causally influences
domain: material entity
range: material entity
definition: The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
term editor: https://orcid.org/0000-0003-4639-4431
term editor: Vasundra Touré
database_cross_reference: RO:0011002
shorthand: regulates_activity_of

regulates quantity of
type: ObjectProperty
sub property of: causally influences
domain: material entity
range: material entity
definition: The entity A has an activity that regulates the quantity or abundance or concentration of the entity B.
term editor: https://orcid.org/0000-0003-4639-4431

indirectly regulates activity of
type: ObjectProperty
sub property of: regulates activity of
domain: material entity
range: material entity
definition: The entity A is not immediately upstream of the entity B but A has an activity that regulates an activity performed by B.
term editor: https://orcid.org/0000-0003-4639-4431

decreases by repression quantity of
type: ObjectProperty
sub property of: indirectly negatively regulates quantity of
domain: material entity
range: material entity
definition: The entity A has an activity that down-regulates by repression the quantity of B. The down-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B. For example, protein A (transcription factor) indirectly decreases by repression the quantity of protein B (gene product) if and only if A negatively regulates the process of transcription or translation of a nucleic acid element that produces B.
term editor: https://orcid.org/0000-0003-4639-4431

increases by expression quantity of
type: ObjectProperty
sub property of: indirectly positively regulates quantity of
domain: material entity
range: material entity
definition: The entity A has an activity that up-regulates by expression the quantity of B. The up-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B. For example, protein A (transcription factor) indirectly increases by expression the quantity of protein B (gene product) if and only if A positively regulates the process of transcription or translation of a nucleic acid element that produces B.
term editor: https://orcid.org/0000-0003-4639-4431

directly positively regulates quantity of
type: ObjectProperty
sub property of: directly regulates quantity of
domain: material entity
range: material entity
definition: The entity A has an activity that directly positively regulates the quantity of B.
term editor: https://orcid.org/0000-0003-4639-4431

directly negatively regulates quantity of
type: ObjectProperty
sub property of: directly regulates quantity of
domain: material entity
range: material entity
definition: The entity A has an activity that directly negatively regulates the quantity of B.
term editor: https://orcid.org/0000-0003-4639-4431

indirectly positively regulates activity of
type: ObjectProperty
sub property of: indirectly regulates activity of
domain: material entity
range: material entity
definition: The entity A is not immediately upstream of the entity B and has an activity that up-regulates an activity performed by B.
term editor: https://orcid.org/0000-0003-4639-4431
alternative term: indirectly activates

destabilizes quantity of
type: ObjectProperty
sub property of: directly negatively regulates quantity of
domain: material entity
range: material entity
example of usage: AKT1 destabilizes quantity of FOXO (interaction from Signor database: SIGNOR-252844)
definition: An entity A directly interacts with B and A has an activity that decreases the amount of an entity B by degradating it.
term editor: https://orcid.org/0000-0003-4639-4431

stabilizes quantity of
type: ObjectProperty
sub property of: directly positively regulates quantity of
domain: material entity
range: material entity
example of usage: AKT1 stabilizes quantity of XIAP (interaction from Signor database: SIGNOR-119488)
definition: An entity A physically interacts with B and A has an activity that increases the amount of an entity B by stabilizing it.
term editor: https://orcid.org/0000-0003-4639-4431

indirectly negatively regulates activity of
type: ObjectProperty
sub property of: indirectly regulates activity of
definition: The entity A is not immediately upstream of the entity B and has an activity that down-regulates an activity performed by B.
term editor: https://orcid.org/0000-0003-4639-4431
alternative term: indirectly inhibits

directly regulates quantity of
type: ObjectProperty
sub property of: regulates quantity of
definition: The entity A, immediately upstream of B, has an activity that directly regulates the quantity of B.
term editor: https://orcid.org/0000-0003-4639-4431

indirectly regulates quantity of
type: ObjectProperty
sub property of: regulates quantity of
definition: The entity A is not immediately upstream of the entity B, but A has an activity that regulates the quantity or abundance or concentration of B.
term editor: https://orcid.org/0000-0003-4639-4431

indirectly negatively regulates quantity of
type: ObjectProperty
sub property of: indirectly regulates quantity of
definition: The entity A does not physically interact with the entity B, and A has an activity that down-regulates the quantity or abundance or concentration of B.
term editor: https://orcid.org/0000-0003-4639-4431

indirectly positively regulates quantity of
type: ObjectProperty
sub property of: indirectly regulates quantity of
definition: The entity A does not physically interact with the entity B, and A has an activity that up-regulates the quantity or abundance or concentration of B.
term editor: https://orcid.org/0000-0003-4639-4431

has small molecule regulator
type: ObjectProperty
sub property of: has participant
inverse of: is small molecule regulator of
definition: a relation between a process and a continuant, in which the process is regulated by the small molecule continuant
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-04-22T20:27:26Z

has small molecule activator
type: ObjectProperty
sub property of: has small molecule regulator
inverse of: is small molecule activator of
definition: a relation between a process and a continuant, in which the process is activated by the small molecule continuant
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-04-22T20:28:37Z

has small molecule inhibitor
type: ObjectProperty
sub property of: has small molecule regulator
inverse of: is small molecule inhibitor of
definition: a relation between a process and a continuant, in which the process is inhibited by the small molecule continuant
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-04-22T20:28:54Z

acts on population of
type: ObjectProperty
sub property of: has participant
definition: p acts on population of c iff c' is a collection, has members of type c, and p has participant c
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-06-08T17:21:33Z
database_cross_reference: RO:0012003
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: acts_on_population_of

is small molecule regulator of
type: ObjectProperty
sub property of: capable of regulating
definition: a relation between a continuant and a process, in which the continuant is a small molecule that regulates the process
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-06-24T13:15:17Z

is small molecule activator of
type: ObjectProperty
sub property of: capable of positively regulating
sub property of: is small molecule regulator of
definition: a relation between a continuant and a process, in which the continuant is a small molecule that activates the process
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-06-24T13:15:26Z

is small molecule inhibitor of
type: ObjectProperty
sub property of: capable of negatively regulating
sub property of: is small molecule regulator of
definition: a relation between a continuant and a process, in which the continuant is a small molecule that inhibits the process
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-06-24T13:15:35Z

results in adhesion of
type: ObjectProperty
sub property of: results in changes to anatomical or cellular structure
definition: The relationship that links anatomical entities with a process that results in the adhesion of two or more entities via the non-covalent interaction of molecules expressed in, located in, and/or adjacent to, those entities.
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2020-08-27T08:13:59Z

results in fusion of
type: ObjectProperty
sub property of: results in organization of
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2021-02-26T07:28:29Z
database_cross_reference: RO:0012008
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_go_ontology
in_subset: valid_for_gocam
shorthand: results_in_fusion_of

constitutively upstream of
type: ObjectProperty
sub property of: causally upstream of, positive effect
definition: p is constitutively upstream of q iff p is causally upstream of q, p is required for execution of q or a part of q, and the execution of p is approximately constant.
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2022-09-26T06:01:01Z
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_gocam

removes input for
type: ObjectProperty
sub property of: causally upstream of, negative effect
definition: p removes input for q iff p is causally upstream of q, there exists some c such that p has_input c and q has_input c, p reduces the levels of c, and c is rate limiting for execution of q.
created by: https://orcid.org/0000-0003-1813-6857
creation date: 2022-09-26T06:06:20Z
in_subset: valid_for_go_annotation_extension
in_subset: valid_for_gocam

indirectly causally upstream of
type: ObjectProperty
sub property of: causally upstream of
definition: p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.
created by: https://orcid.org/0000-0003-1813-6857
created by: pg
creation date: 2022-09-26T06:07:17Z
database_cross_reference: RO:0012011
shorthand: indirectly_causally_upstream_of

indirectly regulates
type: ObjectProperty
sub property of: regulates (processual)
sub property of: indirectly causally upstream of
definition: p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q.
created by: https://orcid.org/0000-0003-1813-6857
created by: pg
creation date: 2022-09-26T06:08:01Z
database_cross_reference: RO:0012012
shorthand: indirectly_regulates

positively regulates in another organism
type: ObjectProperty
sub property of: regulates in another organism
definition: x 'positively regulates in other organism' y if and only if: (x is the realization of a function to increase the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).
is positive form of: regulates in another organism
contributor: https://orcid.org/0000-0003-1813-6857
creation date: 2023-10-12T10:02:28Z
has_exact_synonym: positively regulates in other organism
in_subset: valid_for_go_ontology

negatively regulates in another organism
type: ObjectProperty
sub property of: regulates in another organism
definition: x 'negatively regulates in other organism' y if and only if: (x is the realization of a function to reduce the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).
is negative form of: regulates in another organism
contributor: https://orcid.org/0000-0003-1813-6857
creation date: 2023-10-12T10:02:42Z
has_exact_synonym: negatively regulates in other organism
in_subset: valid_for_go_ontology

has synaptic IO in region
type: ObjectProperty
sub property of: has synaptic terminal in
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:26:52Z
has_exact_synonym: has synaptic input or output in

receives synaptic input in region
type: ObjectProperty
sub property of: has postsynaptic terminal in
sub property of: has synaptic IO in region
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:42:23Z

sends synaptic output to region
type: ObjectProperty
sub property of: has presynaptic terminal in
sub property of: has synaptic IO in region
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of output synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:45:06Z

has synaptic IO throughout
type: ObjectProperty
sub property of: has synaptic IO in region
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses distributed throughout that region (rather than confined to a subregion).
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:52:19Z

receives synaptic input throughout
type: ObjectProperty
sub property of: receives synaptic input in region
sub property of: has synaptic IO throughout
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses distributed throughout that region (rather than confined to a subregion).
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:55:36Z

sends synaptic output throughout
type: ObjectProperty
sub property of: sends synaptic output to region
sub property of: has synaptic IO throughout
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number output synapses distributed throughout that region (rather than confined to a subregion).
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:57:27Z

has sensory dendrite in
type: ObjectProperty
sub property of: has dendrite location
domain: sensory neuron
property chain axiom: part of
definition: Relation between a sensory neuron and some structure in which it receives sensory input via a sensory dendrite.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-20T12:10:09Z
has_exact_synonym: has sensory dendrite location
has_exact_synonym: has sensory terminal in
has_exact_synonym: has sensory terminal location

receives synaptic input from neuron
type: ObjectProperty
sub property of: synapsed by
inverse of: sends synaptic output to cell
definition: A relationship between an anatomical structure (including cells) and a neuron that has a functionally relevant number of chemical synapses to it.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2021-05-26T08:40:18Z

sends synaptic output to cell
type: ObjectProperty
sub property of: synapsed to
definition: A relationship between a neuron and a cell that it has a functionally relevant number of chemical synapses to.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2021-05-26T08:41:07Z
comment: Not restricting range to 'cell' - object may be a muscle containing a cell targeted by the neuron.

disease has infectious agent
type: ObjectProperty
sub property of: disease has basis in
definition: A relationship between a disease and an infectious agent where the material basis of the disease is an infection with some infectious agent.
created by: https://orcid.org/0000-0001-5208-3432

has exemplar data
type: ObjectProperty
sub property of: topObjectProperty
inverse of: exemplar data of
property chain axiom: subcluster of
example of usage: transcriptomically defined cell type X equivalent to ‘cell’ and (has_exemplar_data value [transcriptomic profile data])
definition: A relation between a material entity and some data in which the data is taken as exemplifying the material entity.
editor note: C has_exemplar_data y iff x is an instance of C and y is data about x that is taken as exemplifying of C.
term editor: https://orcid.org/0000-0002-5260-9315
curator note: This relation is not meant to capture the relation between occurrents and data.

exemplar data of
type: ObjectProperty
sub property of: topObjectProperty
term editor: https://orcid.org/0000-0002-5260-9315

subcluster of
type: ObjectProperty
sub property of: part of
type: TransitiveProperty
definition: A relation between a group and another group it is part of but does not fully constitute.
editor note: X subcluster_of Y iff: X and Y are clusters/groups; X != Y; all members of X are also members of Y.
term editor: https://orcid.org/0000-0001-7258-9596
curator note: This is used specifically for sets whose members are specified by some set-forming operator (method of grouping) such as clustering analyses in single cell transcriptomics.

has characterizing marker set
type: ObjectProperty
domain: cell
example of usage: 'Lamp5-like Egln3_1 primary motor cortex GABAergic interneuron (Mus musculus)' subClass_of: has_characterizing_marker_set some 'NS forest marker set of Lamp5-like Egln3_1 MOp (Mouse).'; NS forest marker set of Lamp5-like Egln3_1 SubClass_of: ('has part' some 'Mouse Fbn2') and ('has part' some 'Mouse Chrna7') and ('has part' some 'Mouse Fam19a1').
example of usage: transcriptomically defined cell type X subClass_of: (has_characterizing_marker_set some S1); S1 has_part some gene 1, S1 has_part some gene 2, S1 has_part some gene 3.
definition: A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type.
editor note: C has_characterizing_marker_set y iff: C is a cell type and y is a collection of genes or proteins whose expression is sufficient to distinguish cell type C from most or all other cell types.
curator note: This relation is not meant for cases where set of genes/proteins are only useful as markers in some specific context - e.g. in some specific location. In these cases it is recommended to make a more specific cell class restricted to the relevant context.
contributor: https://orcid.org/0000-0001-7258-9596
has_exact_synonym: has marker gene combination
has_exact_synonym: has marker signature set

different in magnitude relative to
type: ObjectProperty
domain: PATO_0000001
range: PATO_0000001
definition: q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.

Axiom
annotated source: different in magnitude relative to
annotated property: definition
annotated target: q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

increased in magnitude relative to
type: ObjectProperty
sub property of: different in magnitude relative to
domain: PATO_0000001
range: PATO_0000001
definition: q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
comment: This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.

Axiom
annotated source: increased in magnitude relative to
annotated property: definition
annotated target: q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

decreased in magnitude relative to
type: ObjectProperty
sub property of: different in magnitude relative to
domain: PATO_0000001
range: PATO_0000001
definition: q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
comment: This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'.

Axiom
annotated source: decreased in magnitude relative to
annotated property: definition
annotated target: q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

similar in magnitude relative to
type: ObjectProperty
definition: q1 similar_in_magnitude_relative_to q2 if and only if magnitude(q1) =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.

Axiom
annotated source: similar in magnitude relative to
annotated property: definition
annotated target: q1 similar_in_magnitude_relative_to q2 if and only if magnitude(q1) =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

has relative magnitude
type: ObjectProperty

has cross section
type: ObjectProperty
definition: s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.
database_cross_reference: RO:0015011
shorthand: has_cross_section
comment: Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.

Axiom
annotated source: has cross section
annotated property: definition
annotated target: s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

reciprocal of
type: ObjectProperty
definition: q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e.
comment: There are frequently two ways to state the same thing: we can say 'spermatocyte lacks asters' or 'asters absent from spermatocyte'. In this case the quality is 'lacking all parts of type' - it is a (relational) quality of the spermatocyte, and it is with respect to instances of 'aster'. One of the popular requirements of PATO is that it continue to support 'absent', so we need to relate statements which use this quality to the 'lacking all parts of type' quality.

Axiom
annotated source: reciprocal of
annotated property: definition
annotated target: q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e.
database_cross_reference: https://orcid.org/0000-0002-6601-2165

has high plasma membrane amount
type: ObjectProperty
sub property of: has plasma membrane part
domain: cell
example of usage: 'Ly-76 high positive erythrocyte' equivalent to 'enucleate erythrocyte' and (has_high_plasma_membrane_amount some 'lymphocyte antigen 76 (mouse)')
definition: A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface.
contributor: https://orcid.org/0000-0003-1617-8244
contributor: https://orcid.org/0000-0003-1940-6740

Axiom
annotated source: has high plasma membrane amount
annotated property: definition
annotated target: A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface.
database_cross_reference: PMID:19243617

has low plasma membrane amount
type: ObjectProperty
sub property of: has plasma membrane part
domain: cell
example of usage: 'DN2b thymocyte' equivalent to 'DN2 thymocyte' and (has_low_plasma_membrane_amount some 'mast/stem cell growth factor receptor')
definition: A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface.
contributor: https://orcid.org/0000-0003-1617-8244
contributor: https://orcid.org/0000-0003-1940-6740

Axiom
annotated source: has low plasma membrane amount
annotated property: definition
annotated target: A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface.
database_cross_reference: PMID:19243617

has phenotype or disease
type: ObjectProperty
curator note: Do not use this relation directly. It is intended as a grouping for a set of relations regarding presentation of phenotypes and disease.
contributor: https://orcid.org/0000-0002-7463-6306
date: 2021-11-05T17:30:14Z

has disease
type: ObjectProperty
sub property of: has phenotype or disease
definition: A relationship that holds between an organism and a disease. Here a disease is construed broadly as a disposition to undergo pathological processes that exists in an organism because of one or more disorders in that organism.
contributor: https://orcid.org/0000-0002-7463-6306
date: 2021-11-05T17:30:44Z

has exposure medium
type: ObjectProperty
sub property of: related via exposure to
definition: X has exposure medium Y if X is an exposure event (process), Y is a material entity, and the stimulus for X is transmitted or carried in Y.
definition source: ExO:0000083
creator: https://orcid.org/0000-0002-7463-6306
date: 2021-12-14T20:41:45Z

device utilizes material
type: ObjectProperty
property chain axiom: capable of
property chain axiom: has input
example of usage: A diagnostic testing device utilizes a specimen.
definition: X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
term editor: https://orcid.org/0000-0001-9625-1899
term editor: https://orcid.org/0000-0003-2620-0345
curator note: A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.
curator note: See github ticket https://github.com/oborel/obo-relations/issues/497
creation date: 2021-11-08T12:00:00Z
has_broad_synonym: utilizes
database_cross_reference: RO:0017001
shorthand: device_utilizes_material

positively correlated with
type: ObjectProperty
sub property of: correlated with
type: SymmetricProperty
type: ReflexiveProperty
definition: A relation between entities in which one increases or decreases as the other does the same.
alternative term: directly correlated with
contributor: https://orcid.org/0000-0003-1909-9269

negatively correlated with
type: ObjectProperty
sub property of: correlated with
type: SymmetricProperty
type: IrreflexiveProperty
definition: A relation between entities in which one increases as the other decreases.
alternative term: inversely correlated with
contributor: https://orcid.org/0000-0003-1909-9269

contains measured amount
type: ObjectProperty
domain: OBI_0000967
range: COB_0000121
example of usage: anticoagulant-containing test tube contains measured amount 5 ml of blood specimen.
definition: A relation between a container and measurement datum that specifies the actual amount of material in the container.
contributor: https://orcid.org/0000-0002-2999-0103
contributor: 0000-0002-5714-991X

is myristoyltransferase activity
type: ObjectProperty
sub property of: molecular interaction relation helper property
definition: Helper relation for OWL definition of RO:0018002 myristoylates
contributor: https://orcid.org/0000-0003-4423-4370

myristoylates
type: ObjectProperty
sub property of: molecularly interacts with
inverse of: myristoylated by
property chain axiom: capable of
property chain axiom: is myristoyltransferase activity
property chain axiom: has direct input
definition: A molecularly-interacts-with relationship between two entities, where the subject catalyzes a myristoylation activity that takes the object as input
conforms to: ObjectPropertyDefinedByInteractionProcess
contributor: https://orcid.org/0000-0003-4423-4370

myristoylated by
type: ObjectProperty
definition: inverse of myristoylates
contributor: https://orcid.org/0000-0003-4423-4370

is agonist of
type: ObjectProperty
sub property of: directly positively regulates activity of
example of usage: mibolerone (CHEBI:34849) is agonist of androgen receptor (PR:P10275)
definition: a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor activates some activity of the receptor
creator: https://orcid.org/0000-0003-4423-4370

is inverse agonist of
type: ObjectProperty
sub property of: directly negatively regulates activity of
example of usage: pimavanserin (CHEBI:133017) is inverse agonist of HTR2A (PR:P28223)
definition: a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor inhibits some activity of the receptor to below basal level
creator: https://orcid.org/0000-0003-4423-4370

is antagonist of
type: ObjectProperty
sub property of: directly negatively regulates activity of
example of usage: tretinoin (CHEBI:15367) is antagonist of Nuclear receptor ROR-beta (PR:Q92753)
definition: a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor reduces some activity of the receptor to basal level
creator: https://orcid.org/0000-0003-4423-4370

chemical relationship
type: ObjectProperty
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, in which the subject or object is a chemical.
creator: https://orcid.org/0000-0003-4423-4370

is direct conjugate base of
type: ObjectProperty
sub property of: is deprotonated form of
inverse of: is direct conjugate acid of
example of usage: pyruvate anion (CHEBI:15361) is the conjugate base of the neutral pyruvic acid (CHEBI:32816)
definition: A is a direct conjugate base of B if and only if A is chemical entity that is a Brønsted–Lowry Base (i.e., can receive a proton) and by receiving a particular proton transforms it into B.
is direct form of: is deprotonated form of
creator: https://orcid.org/0000-0003-4423-4370

is direct conjugate acid of
type: ObjectProperty
sub property of: is protonated form of
example of usage: neutral pyruvic acid (CHEBI:32816) is the conjugate acid of the pyruvate anion (CHEBI:15361)
definition: A is a direct conjugate acid of B if and only if A is chemical entity that is a Brønsted–Lowry Acid (i.e., can give up a proton) and by removing a particular proton transforms it into B.
is direct form of: is protonated form of
creator: https://orcid.org/0000-0003-4423-4370

is deprotonated form of
type: ObjectProperty
sub property of: chemical relationship
inverse of: is protonated form of
type: TransitiveProperty
example of usage: (E)-cinnamoyl-CoA(4-) (CHEBI:57252) is a deprotonated form (E)-cinnamoyl-CoA (CHEBI:10956), which involves removing four protons.
definition: A is a deprotonated form of B if and only if A is chemical entity that is a Brønsted–Lowry Base (i.e., can receive a proton) and by adding some nonzero number of protons transforms it into B. This is a transitive relationship and follows this design pattern: https://oborel.github.io/obo-relations/direct-and-indirect-relations.
creator: https://orcid.org/0000-0003-4423-4370
database_cross_reference: obo:chebi#is_conjugate_base_of

is protonated form of
type: ObjectProperty
sub property of: chemical relationship
type: TransitiveProperty
example of usage: (E)-cinnamoyl-CoA (CHEBI:10956) is a protonated form of (E)-cinnamoyl-CoA(4-) (CHEBI:57252), which involves adding four protons.
definition: A is a protonated form of B if and only if A is chemical entity that is a Brønsted–Lowry Acid (i.e., can give up a proton) and by removing some nonzero number of protons transforms it into B. This is a transitive relationship and follows this design pattern: https://oborel.github.io/obo-relations/direct-and-indirect-relations.
creator: https://orcid.org/0000-0003-4423-4370
database_cross_reference: obo:chebi#is_conjugate_acid_of

is matched small molecular pair with
type: ObjectProperty
sub property of: chemical relationship
type: SymmetricProperty
example of usage: phenol (CHEBI:15882) and aniline (CHEBI:17296) are matched molecular pairs because they differ by one chemical transformation i.e., the replacement of aryl primary amine with aryl primary alcohol.
definition: A and B are a matched small molecular pair (MMP) if their chemical structures define by a single, relatively small, well-defined structural modification. While this is normally called "matched molecular pair" in the cheminformatics literaturel, it is labeled as "matched small molecular pair" so as to reduce confusion with peptides and other macromolecules, which are also referenced as "molecules" in some contexts. This relationship is symmetric, meaning if A is a MMP with B iff B is a MMP with A. This relationship is not transitive, meaning that A is a MMP with B and B is a MMP with C, then A is not necessarily an MMP with C.
creator: https://orcid.org/0000-0003-4423-4370
date: 2023-02-28T18:53:32Z
has_exact_synonym: is MMP with
has_exact_synonym: is matched molecular pair with

Axiom
annotated source: is matched small molecular pair with
annotated property: definition
annotated target: A and B are a matched small molecular pair (MMP) if their chemical structures define by a single, relatively small, well-defined structural modification. While this is normally called "matched molecular pair" in the cheminformatics literaturel, it is labeled as "matched small molecular pair" so as to reduce confusion with peptides and other macromolecules, which are also referenced as "molecules" in some contexts. This relationship is symmetric, meaning if A is a MMP with B iff B is a MMP with A. This relationship is not transitive, meaning that A is a MMP with B and B is a MMP with C, then A is not necessarily an MMP with C.
source: ddr.21045
source: jm200452d
source: Matched molecular pair analysis

is tautomer of
type: ObjectProperty
sub property of: chemical relationship
type: SymmetricProperty
example of usage: 3-carboxy-3-mercaptopropanoate (CHEBI:38707) is tautomer of 1,2-dicarboxyethanethiolate (CHEBI:38709) because 3-carboxy-3-mercaptopropanoate is deprotonated on the carboxylic acid whereas 1,2-dicarboxyethanethiolate is deprotonated on the secondary thiol.
definition: Two chemicals are tautomers if they can be readily interconverted. This commonly refers to prototropy in which a hydrogen's position is changed, such as between ketones and enols. This is also often observed in heterocyclic rings, e.g., ones containing nitrogens and/or have aryl functional groups containing heteroatoms.
creator: https://orcid.org/0000-0003-4423-4370
date: 2023-03-18T23:49:31Z
database_cross_reference: obo:chebi#is_tautomer_of
has_exact_synonym: is desmotrope of

Axiom
annotated source: is tautomer of
annotated property: example of usage
annotated target: 3-carboxy-3-mercaptopropanoate (CHEBI:38707) is tautomer of 1,2-dicarboxyethanethiolate (CHEBI:38709) because 3-carboxy-3-mercaptopropanoate is deprotonated on the carboxylic acid whereas 1,2-dicarboxyethanethiolate is deprotonated on the secondary thiol.

is substitutent group from
type: ObjectProperty
sub property of: chemical relationship
example of usage: carboxylatoacetyl group (CHEBI:58957) is substituent group from malonate(1-) (CHEBI:30795)
definition: Group A is a substituent group from Chemical B if A represents the functional part of A and includes information about where it is connected. A is not itself a chemical with a fully formed chemical graph, but is rather a partial graph with one or more connection points that can be used to attach to another chemical graph, typically as a functionalization.
creator: https://orcid.org/0000-0003-4423-4370
date: 2023-03-18T23:49:31Z
database_cross_reference: obo:chebi#is_substituent_group_from

Axiom
annotated source: is substitutent group from
annotated property: example of usage
annotated target: carboxylatoacetyl group (CHEBI:58957) is substituent group from malonate(1-) (CHEBI:30795)

has functional parent
type: ObjectProperty
sub property of: chemical relationship
example of usage: hydrocortamate hydrochloride (CHEBI:50854) has parent hydride hydrocortamate (CHEBI:50851)
definition: Chemical A has functional parent Chemical B if there is chemical transformation through which chemical B can be produced from chemical A. For example, the relationship between a salt and a freebased compound is a "has functional parent" relationship.
creator: https://orcid.org/0000-0003-4423-4370
date: 2023-03-18T23:49:31Z
database_cross_reference: obo:chebi#has_functional_parent

Axiom
annotated source: has functional parent
annotated property: example of usage
annotated target: hydrocortamate hydrochloride (CHEBI:50854) has parent hydride hydrocortamate (CHEBI:50851)

is enantiomer of
type: ObjectProperty
sub property of: chemical relationship
type: SymmetricProperty
example of usage: dexmedetomidine hydrochloride (CHEBI:31472) is enantiomer of levomedetomidine hydrochloride (CHEBI:48557) because the stereochemistry of the central chiral carbon is swapped.
definition: Chemicals A and B are enantiomers if they share the same molecular graph except the change of the configuration of substituents around exactly one chiral center. A chemical with no chiral centers can not have an enantiomer. A chemical with multiple chiral centers can have multiple enantiomers, but its enantiomers are not themselves enantiomers (they are diastereomers).
creator: https://orcid.org/0000-0003-4423-4370
date: 2023-03-18T23:49:31Z
database_cross_reference: obo:chebi#is_enantiomer_of
has_exact_synonym: is optical isomer of

Axiom
annotated source: is enantiomer of
annotated property: example of usage
annotated target: dexmedetomidine hydrochloride (CHEBI:31472) is enantiomer of levomedetomidine hydrochloride (CHEBI:48557) because the stereochemistry of the central chiral carbon is swapped.
comment: CHEBI_48557

has parent hydride
type: ObjectProperty
sub property of: chemical relationship
example of usage: pyranine (CHEBI:52083) has parent hydride pyrene (CHEBI:39106). Pyrene is molecule with four fused benzene rings, whereas pyranine has the same core ring structure with additional sulfates.
definition: Chemical A has parent hydride Chemical B if there exists a molecular graphical transformation where functional groups on A are replaced with hydrogens in order to yield B.
creator: https://orcid.org/0000-0003-4423-4370
date: 2023-03-18T23:49:31Z
database_cross_reference: obo:chebi#has_parent_hydride

Axiom
annotated source: has parent hydride
annotated property: example of usage
annotated target: pyranine (CHEBI:52083) has parent hydride pyrene (CHEBI:39106). Pyrene is molecule with four fused benzene rings, whereas pyranine has the same core ring structure with additional sulfates.

regulates characteristic
type: ObjectProperty
sub property of: causally related to
domain: process
range: PATO_0000001
property chain axiom: regulates (processual)
definition: A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.
contributor: https://orcid.org/0000-0002-8688-6599
database_cross_reference: RO:0019000
shorthand: regulates_characteristic

positively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
property chain axiom: positively regulates
definition: A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.
contributor: https://orcid.org/0000-0002-8688-6599
database_cross_reference: RO:0019001
shorthand: positively_regulates_characteristic

negatively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
property chain axiom: negatively regulates
property chain axiom: positively regulates characteristic
property chain axiom: positively regulates
definition: A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.
contributor: https://orcid.org/0000-0002-8688-6599
database_cross_reference: RO:0019002
shorthand: negatively_regulates_characteristic

confers susceptibility to condition
type: ObjectProperty
sub property of: contributes to condition
definition: Relates a gene to condition, such that a variation in this gene predisposes to the development of a condition.
created by: https://orcid.org/0000-0002-4142-7153

vessel supplies blood to
type: ObjectProperty
sub property of: supplies
domain: UBERON_0001981
range: UBERON_0000061
example of usage: brachial artery vessel supplies blood to brachialis muscle
definition: x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-02-01T10:09:22Z

vessel drains blood from
type: ObjectProperty
sub property of: drains
domain: UBERON_0001981
range: UBERON_0000061
example of usage: cystic vein vessel drains blood from gallbladder
definition: x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-02-01T10:09:41Z

directly supplies and drains
type: ObjectProperty
sub property of: supplies
sub property of: drains
domain: UBERON_0001982
range: UBERON_0000061
example of usage: alveolar capillary directly supplies and drains some alveolus
definition: x directly supplies and drains y if and only if x is a capillary, y is an anatomical entity, and x directly supplies and drains y.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-02-01T10:09:59Z

disease relationship
type: ObjectProperty
definition: This relation groups relations between diseases and any other kind of entity.
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, in which the subject or object is a disease.
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-09-26T00:00:32Z

results in changes to anatomical or cellular structure
type: ObjectProperty
sub property of: has participant
definition: p has anatomical participant c iff p has participant c, and c is an anatomical entity
created by: https://orcid.org/0000-0002-6601-2165
creation date: 2018-09-26T01:08:58Z
database_cross_reference: RO:0040036
shorthand: results_in_changes_to_anatomical_or_cellular_structure

in similarity relationship with
type: ObjectProperty
type: SymmetricProperty
definition: Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison.
editor note: TODO: Add homeomorphy axiom
is homeomorphic for: continuant
is homeomorphic for: occurrent
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: ECO:0000041
database_cross_reference: SO:similar_to
has_exact_synonym: sameness
has_exact_synonym: similar to
has_related_synonym: correspondence
has_related_synonym: resemblance

Axiom
annotated source: in similarity relationship with
annotated property: definition
annotated target: Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison.
database_cross_reference: HOM_0000000
database_cross_reference: BGEE:curator

Axiom
annotated source: in similarity relationship with
annotated property: has_related_synonym
annotated target: correspondence
database_cross_reference: http://dx.doi.org/10.1007/BF02814479

in homology relationship with
type: ObjectProperty
sub property of: shares ancestor with
sub property of: in similarity relationship with
type: SymmetricProperty
property disjoint with: in homoplasy relationship with
definition: Similarity that results from common evolutionary origin.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: homologous to
comment: This broad definition encompasses all the working definitions proposed so far in the literature.

Axiom
annotated source: in homology relationship with
annotated property: definition
annotated target: Similarity that results from common evolutionary origin.
database_cross_reference: bies.950180611
database_cross_reference: jmor.1051730307
database_cross_reference: http://dx.doi.org/10.1007/BF02814480
database_cross_reference: HOM_0000001

in homoplasy relationship with
type: ObjectProperty
sub property of: in similarity relationship with
type: SymmetricProperty
definition: Similarity that results from independent evolution.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: homoplasous to
has_related_synonym: analogy

Axiom
annotated source: in homoplasy relationship with
annotated property: definition
annotated target: Similarity that results from independent evolution.
database_cross_reference: j.jhevol.2006.11.010
database_cross_reference: HOM_0000002

in homocracy relationship with
type: ObjectProperty
sub property of: evolutionarily related to
sub property of: in similarity relationship with
type: SymmetricProperty
definition: Similarity that is characterized by the organization of anatomical structures through the expression of homologous or identical patterning genes.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: ECO:0000075
has_exact_synonym: homocracous to
comment: Homology and homocracy are not mutually exclusive. The homology relationships of patterning genes may be unresolved and thus may include orthologues and paralogues.

Axiom
annotated source: in homocracy relationship with
annotated property: definition
annotated target: Similarity that is characterized by the organization of anatomical structures through the expression of homologous or identical patterning genes.
database_cross_reference: http://dx.doi.org/10.1007/BF02814484
database_cross_reference: s00427-003-0301-4
database_cross_reference: http://dx.doi.org/10.1186/1742-9994-2-15
database_cross_reference: HOM_0000003

in convergence relationship with
type: ObjectProperty
sub property of: in homoplasy relationship with
type: SymmetricProperty
definition: Homoplasy that involves different underlying mechanisms or structures.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_related_synonym: analogy
comment: Convergence usually implies a notion of adaptation.

Axiom
annotated source: in convergence relationship with
annotated property: definition
annotated target: Homoplasy that involves different underlying mechanisms or structures.
database_cross_reference: j.jhevol.2006.11.010
database_cross_reference: HOM_0000004

in parallelism relationship with
type: ObjectProperty
sub property of: in homoplasy relationship with
type: SymmetricProperty
definition: Homoplasy that involves homologous underlying mechanisms or structures.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: parallel evolution
comment: Can be applied for features present in closely related organisms but not present continuously in all the members of the lineage.

Axiom
annotated source: in parallelism relationship with
annotated property: definition
annotated target: Homoplasy that involves homologous underlying mechanisms or structures.
database_cross_reference: j.jhevol.2006.11.010
database_cross_reference: HOM_0000005

in structural homology relationship with
type: ObjectProperty
sub property of: in homology relationship with
type: SymmetricProperty
definition: Homology that is defined by similarity with regard to selected structural parameters.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: ECO:0000071
database_cross_reference: MI:2163
has_exact_synonym: structural homologous to
has_related_synonym: idealistic homology

Axiom
annotated source: in structural homology relationship with
annotated property: definition
annotated target: Homology that is defined by similarity with regard to selected structural parameters.
database_cross_reference: j.jhevol.2006.11.014
database_cross_reference: annurev.es.20.110189.000411
database_cross_reference: HOM_0000006
database_cross_reference: ISBN:0123195837

in historical homology relationship with
type: ObjectProperty
sub property of: in homology relationship with
type: SymmetricProperty
definition: Homology that is defined by common descent.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_broad_synonym: homology
database_cross_reference: ECO:0000080
database_cross_reference: RO_proposed_relation:homologous_to
database_cross_reference: SO:0000330
database_cross_reference: SO:0000853
database_cross_reference: SO:0000857
database_cross_reference: SO:homologous_to
database_cross_reference: TAO:homologous_to
has_exact_synonym: cladistic homology
has_exact_synonym: historical homologous to
has_exact_synonym: phylogenetic homology
has_exact_synonym: taxic homology
has_related_synonym: true homology

Axiom
annotated source: in historical homology relationship with
annotated property: definition
annotated target: Homology that is defined by common descent.
database_cross_reference: S0169-5347(97)01125-7
database_cross_reference: HOM_0000007
database_cross_reference: ISBN:0123195837

in biological homology relationship with
type: ObjectProperty
sub property of: in homology relationship with
type: SymmetricProperty
definition: Homology that is defined by sharing of a set of developmental constraints, caused by locally acting self-regulatory mechanisms of differentiation, between individualized parts of the phenotype.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: ECO:0000067
has_exact_synonym: biological homologous to
has_related_synonym: transformational homology
comment: Applicable only to morphology. A certain degree of ambiguity is accepted between biological homology and parallelism.

Axiom
annotated source: in biological homology relationship with
annotated property: definition
annotated target: Homology that is defined by sharing of a set of developmental constraints, caused by locally acting self-regulatory mechanisms of differentiation, between individualized parts of the phenotype.
database_cross_reference: S0169-5347(97)01125-7
database_cross_reference: annurev.es.20.110189.000411
database_cross_reference: HOM_0000008

in reversal relationship with
type: ObjectProperty
sub property of: in homoplasy relationship with
type: SymmetricProperty
definition: Homoplasy that involves phenotypes similar to those seen in ancestors within the lineage.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: atavism
has_exact_synonym: rudiment
has_related_synonym: reversion

Axiom
annotated source: in reversal relationship with
annotated property: definition
annotated target: Homoplasy that involves phenotypes similar to those seen in ancestors within the lineage.
database_cross_reference: j.jhevol.2006.11.010
database_cross_reference: HOM_0000009

in syntenic homology relationship with
type: ObjectProperty
sub property of: in structural homology relationship with
type: SymmetricProperty
definition: Structural homology that is detected by similarity in content and organization between chromosomes.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: MeSH:Synteny
database_cross_reference: SO:0000860
database_cross_reference: SO:0005858
has_exact_synonym: syntenic homologous to
has_related_synonym: synteny

Axiom
annotated source: in syntenic homology relationship with
annotated property: definition
annotated target: Structural homology that is detected by similarity in content and organization between chromosomes.
database_cross_reference: HOM_0000010
database_cross_reference: MeSH:Synteny

in paralogy relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
property disjoint with: in orthology relationship with
definition: Historical homology that involves genes that diverged after a duplication event.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: SO:0000854
database_cross_reference: SO:0000859
database_cross_reference: SO:paralogous_to
has_exact_synonym: paralogous to

Axiom
annotated source: in paralogy relationship with
annotated property: definition
annotated target: Historical homology that involves genes that diverged after a duplication event.
database_cross_reference: S0168-9525(00)02005-9
database_cross_reference: annurev.genet.39.073003.114725
database_cross_reference: HOM_0000011
database_cross_reference: http://www.ncbi.nlm.nih.gov/pubmed/5449325

in syntenic paralogy relationship with
type: ObjectProperty
sub property of: in syntenic homology relationship with
sub property of: in paralogy relationship with
type: SymmetricProperty
definition: Paralogy that involves sets of syntenic blocks.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: syntenic paralogous to
has_related_synonym: duplicon
has_related_synonym: paralogon

Axiom
annotated source: in syntenic paralogy relationship with
annotated property: definition
annotated target: Paralogy that involves sets of syntenic blocks.
database_cross_reference: 1471-213X-7-100
database_cross_reference: HOM_0000012
database_cross_reference: DOI:10.1002/1097-010X(20001215)288:4<345::AID-JEZ7>3.0.CO;2-Y

in syntenic orthology relationship with
type: ObjectProperty
sub property of: in syntenic homology relationship with
type: SymmetricProperty
definition: Syntenic homology that involves chromosomes of different species.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: syntenic orthologous to

Axiom
annotated source: in syntenic orthology relationship with
annotated property: definition
annotated target: Syntenic homology that involves chromosomes of different species.
database_cross_reference: gr.6380007
database_cross_reference: HOM_0000013

in partial homology relationship with
type: ObjectProperty
sub property of: in structural homology relationship with
type: SymmetricProperty
definition: Structural homology that involves complex structures from which only a fraction of the elements that can be isolated are separately homologous.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: fractional homology
has_exact_synonym: partial homologous to
has_exact_synonym: segmental homology
has_related_synonym: mixed homology
has_related_synonym: modular homology
has_related_synonym: partial correspondence
has_related_synonym: percent homology

Axiom
annotated source: in partial homology relationship with
annotated property: definition
annotated target: Structural homology that involves complex structures from which only a fraction of the elements that can be isolated are separately homologous.
database_cross_reference: HOM_0000014
database_cross_reference: ISBN:0123195837
database_cross_reference: ISBN:978-0471984931

in protein structural homology relationship with
type: ObjectProperty
sub property of: in structural homology relationship with
type: SymmetricProperty
definition: Structural homology that is detected at the level of the 3D protein structure, but maybe not at the level of the amino acid sequence.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: MeSH:Structural_Homology,_Protein
has_exact_synonym: protein structural homologous to

Axiom
annotated source: in protein structural homology relationship with
annotated property: definition
annotated target: Structural homology that is detected at the level of the 3D protein structure, but maybe not at the level of the amino acid sequence.
database_cross_reference: 0022-2836(76)90195-9
database_cross_reference: HOM_0000015

in non functional homology relationship with
type: ObjectProperty
sub property of: in structural homology relationship with
type: SymmetricProperty
property disjoint with: in equivalogy relationship with
definition: Structural homology that involves a pseudogenic feature and its functional ancestor.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_broad_synonym: pseudogene
database_cross_reference: SO:non_functional_homolog_of
has_exact_synonym: non functional homologous to

Axiom
annotated source: in non functional homology relationship with
annotated property: definition
annotated target: Structural homology that involves a pseudogenic feature and its functional ancestor.
database_cross_reference: HOM_0000016
database_cross_reference: SO:non_functional_homolog_of

in orthology relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that involves genes that diverged after a speciation event.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: ECO:00000060
database_cross_reference: SO:0000855
database_cross_reference: SO:0000858
database_cross_reference: SO:orthologous_to
has_exact_synonym: orthologous to
comment: The term is sometimes also used for anatomical structures.

Axiom
annotated source: in orthology relationship with
annotated property: definition
annotated target: Historical homology that involves genes that diverged after a speciation event.
database_cross_reference: http://dx.doi.org/10.1007/BF02814484
database_cross_reference: S0168-9525(00)02005-9
database_cross_reference: annurev.genet.39.073003.114725
database_cross_reference: HOM_0000017
database_cross_reference: http://www.ncbi.nlm.nih.gov/pubmed/5449325

in xenology relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that is characterized by an interspecies (horizontal) transfer since the common ancestor.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: xenologous to
comment: The term is sometimes also used for anatomical structures (e.g. in case of a symbiosis).

Axiom
annotated source: in xenology relationship with
annotated property: definition
annotated target: Historical homology that is characterized by an interspecies (horizontal) transfer since the common ancestor.
database_cross_reference: S0168-9525(00)02005-9
database_cross_reference: annurev.genet.39.073003.114725
database_cross_reference: HOM_0000018

in 1 to 1 homology relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that involves two members sharing no other homologs in the lineages considered.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: 1 to 1 homologous to
has_exact_synonym: 1:1 homology
has_exact_synonym: one-to-one homology

Axiom
annotated source: in 1 to 1 homology relationship with
annotated property: definition
annotated target: Historical homology that involves two members sharing no other homologs in the lineages considered.
database_cross_reference: HOM_0000019
database_cross_reference: BGEE:curator

in 1 to 1 orthology relationship with
type: ObjectProperty
sub property of: in orthology relationship with
sub property of: in 1 to 1 homology relationship with
type: SymmetricProperty
definition: Orthology that involves two genes that did not experience any duplication after the speciation event that created them.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: 1 to 1 orthologous to
has_exact_synonym: 1:1 orthology
has_exact_synonym: one-to-one orthology

Axiom
annotated source: in 1 to 1 orthology relationship with
annotated property: definition
annotated target: Orthology that involves two genes that did not experience any duplication after the speciation event that created them.
database_cross_reference: http://dx.doi.org/10.1007/BF02814484
database_cross_reference: HOM_0000020
database_cross_reference: homology method.html

in ohnology relationship with
type: ObjectProperty
sub property of: in paralogy relationship with
type: SymmetricProperty
definition: Paralogy that results from a whole genome duplication event.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: ohnologous to
has_related_synonym: homoeology

Axiom
annotated source: in ohnology relationship with
annotated property: definition
annotated target: Paralogy that results from a whole genome duplication event.
database_cross_reference: http://dx.doi.org/10.1038/75560
database_cross_reference: HOM_0000022

in in-paralogy relationship with
type: ObjectProperty
sub property of: in paralogy relationship with
type: SymmetricProperty
property disjoint with: in out-paralogy relationship with
definition: Paralogy that results from a lineage-specific duplication subsequent to a given speciation event.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: in-paralogous to
has_exact_synonym: inparalogy
has_exact_synonym: symparalogy

Axiom
annotated source: in in-paralogy relationship with
annotated property: definition
annotated target: Paralogy that results from a lineage-specific duplication subsequent to a given speciation event.
database_cross_reference: annurev.genet.39.073003.114725
database_cross_reference: HOM_0000023

in out-paralogy relationship with
type: ObjectProperty
sub property of: in paralogy relationship with
type: SymmetricProperty
definition: Paralogy that results from a duplication preceding a given speciation event.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: alloparalogy
has_exact_synonym: out-paralogous to
has_exact_synonym: outparalogy

Axiom
annotated source: in out-paralogy relationship with
annotated property: definition
annotated target: Paralogy that results from a duplication preceding a given speciation event.
database_cross_reference: annurev.genet.39.073003.114725
database_cross_reference: HOM_0000024

in pro-orthology relationship with
type: ObjectProperty
sub property of: in 1 to many orthology relationship with
type: SymmetricProperty
definition: 1:many orthology that involves a gene in species A and one of its ortholog in species B, when duplications more recent than the species split have occurred in species B but not in species A.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: pro-orthologous to

Axiom
annotated source: in pro-orthology relationship with
annotated property: definition
annotated target: 1:many orthology that involves a gene in species A and one of its ortholog in species B, when duplications more recent than the species split have occurred in species B but not in species A.
database_cross_reference: scdb.1999.0338
database_cross_reference: nrg2099
database_cross_reference: HOM_0000025

in semi-orthology relationship with
type: ObjectProperty
sub property of: in 1 to many orthology relationship with
type: SymmetricProperty
definition: 1:many orthology that involves a gene in species A and its ortholog in species B, when duplications more recent than the species split have occurred in species A but not in species B.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: semi-orthologous to
comment: The converse of pro-orthologous.

Axiom
annotated source: in semi-orthology relationship with
annotated property: definition
annotated target: 1:many orthology that involves a gene in species A and its ortholog in species B, when duplications more recent than the species split have occurred in species A but not in species B.
database_cross_reference: scdb.1999.0338
database_cross_reference: nrg2099
database_cross_reference: HOM_0000026

in serial homology relationship with
type: ObjectProperty
sub property of: in iterative homology relationship with
type: SymmetricProperty
definition: Iterative homology that involves structures arranged along the main body axis.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: serial homologous to
has_related_synonym: homonomy

Axiom
annotated source: in serial homology relationship with
annotated property: definition
annotated target: Iterative homology that involves structures arranged along the main body axis.
database_cross_reference: annurev.es.20.110189.000411
database_cross_reference: HOM_0000027

in heterochronous homology relationship with
type: ObjectProperty
sub property of: in biological homology relationship with
type: SymmetricProperty
definition: Biological homology that is characterized by changes, over evolutionary time, in the rate or timing of developmental events of homologous structures.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: heterochronous homologous to
has_exact_synonym: heterochrony

Axiom
annotated source: in heterochronous homology relationship with
annotated property: definition
annotated target: Biological homology that is characterized by changes, over evolutionary time, in the rate or timing of developmental events of homologous structures.
database_cross_reference: HOM_0000028
database_cross_reference: ISBN:978-0674639416

in paedomorphorsis relationship with
type: ObjectProperty
sub property of: in heterochronous homology relationship with
type: SymmetricProperty
property disjoint with: in peramorphosis relationship with
definition: Heterochronous homology that is produced by a retention in adults of a species of traits previously seen only in juveniles.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: juvenification
has_exact_synonym: pedomorphosis

Axiom
annotated source: in paedomorphorsis relationship with
annotated property: definition
annotated target: Heterochronous homology that is produced by a retention in adults of a species of traits previously seen only in juveniles.
database_cross_reference: Pedomorphosis
database_cross_reference: HOM_0000029
database_cross_reference: ISBN:978-0674639416

in peramorphosis relationship with
type: ObjectProperty
sub property of: in heterochronous homology relationship with
type: SymmetricProperty
definition: Heterochronous homology that is produced by a maturation of individuals of a species past adulthood, which take on hitherto unseen traits.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127

Axiom
annotated source: in peramorphosis relationship with
annotated property: definition
annotated target: Heterochronous homology that is produced by a maturation of individuals of a species past adulthood, which take on hitherto unseen traits.
database_cross_reference: Peramorphosis
database_cross_reference: HOM_0000030

in progenesis relationship with
type: ObjectProperty
sub property of: in paedomorphorsis relationship with
type: SymmetricProperty
definition: Paedomorphosis that is produced by precocious sexual maturation of an organism still in a morphologically juvenile stage.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127

Axiom
annotated source: in progenesis relationship with
annotated property: definition
annotated target: Paedomorphosis that is produced by precocious sexual maturation of an organism still in a morphologically juvenile stage.
database_cross_reference: Progenesis
database_cross_reference: HOM_0000031
database_cross_reference: ISBN:978-0674639416

in neoteny relationship with
type: ObjectProperty
sub property of: in paedomorphorsis relationship with
type: SymmetricProperty
definition: Paedomorphosis that is produced by a retardation of somatic development.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: juvenilization
has_exact_synonym: neotenous to

Axiom
annotated source: in neoteny relationship with
annotated property: definition
annotated target: Paedomorphosis that is produced by a retardation of somatic development.
database_cross_reference: Neoteny
database_cross_reference: HOM_0000032
database_cross_reference: ISBN:978-0674639416

in mimicry relationship with
type: ObjectProperty
sub property of: in convergence relationship with
type: SymmetricProperty
definition: Convergence that results from co-evolution usually involving an evolutionary arms race.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: mimicrous to

Axiom
annotated source: in mimicry relationship with
annotated property: definition
annotated target: Convergence that results from co-evolution usually involving an evolutionary arms race.
database_cross_reference: Mimicry
database_cross_reference: HOM_0000033

in 1 to many orthology relationship with
type: ObjectProperty
sub property of: in orthology relationship with
sub property of: in 1 to many homology relationship with
type: SymmetricProperty
definition: Orthology that involves two genes when duplications more recent than the species split have occurred in one species but not the other.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: 1 to many orthologous to
has_exact_synonym: 1:many orthology
has_exact_synonym: one-to-many orthology
has_related_synonym: co-orthology
has_related_synonym: many to 1 orthology

Axiom
annotated source: in 1 to many orthology relationship with
annotated property: definition
annotated target: Orthology that involves two genes when duplications more recent than the species split have occurred in one species but not the other.
database_cross_reference: 415741a
database_cross_reference: HOM_0000034
database_cross_reference: homology method.html

in many to many homology relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that involves two members of a larger set of homologs.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: many to many homologous to
has_exact_synonym: many-to-many homology
has_exact_synonym: many:many homology

Axiom
annotated source: in many to many homology relationship with
annotated property: definition
annotated target: Historical homology that involves two members of a larger set of homologs.
database_cross_reference: msp002
database_cross_reference: HOM_0000036

in 1 to many homology relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that involves a structure that has no other homologs in the species in which it is defined, and several homologous structures in another species.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: 1 to many homologous to
has_exact_synonym: one-to-many homology
has_related_synonym: 1:many homology

Axiom
annotated source: in 1 to many homology relationship with
annotated property: definition
annotated target: Historical homology that involves a structure that has no other homologs in the species in which it is defined, and several homologous structures in another species.
database_cross_reference: HOM_0000037
database_cross_reference: BGEE:curator

in apomorphy relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
property disjoint with: in plesiomorphy relationship with
definition: Historical homology that is based on recent shared ancestry, characterizing a monophyletic group.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: apomorphous to
has_related_synonym: synapomorphy

Axiom
annotated source: in apomorphy relationship with
annotated property: definition
annotated target: Historical homology that is based on recent shared ancestry, characterizing a monophyletic group.
database_cross_reference: HOM_0000042
database_cross_reference: ISBN:978-0252068140

in plesiomorphy relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that is based on distant shared ancestry.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: plesiomorphous to
has_related_synonym: symplesiomorphy
comment: This term is usually contrasted to apomorphy.

Axiom
annotated source: in plesiomorphy relationship with
annotated property: definition
annotated target: Historical homology that is based on distant shared ancestry.
database_cross_reference: HOM_0000043
database_cross_reference: ISBN:978-0252068140

in deep homology relationship with
type: ObjectProperty
sub property of: in homocracy relationship with
sub property of: in parallelism relationship with
type: SymmetricProperty
definition: Homocracy that involves morphologically and phylogenetically disparate structures that are the result of parallel evolution.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: deep genetic homology
has_exact_synonym: deep homologous to
has_related_synonym: generative homology
has_related_synonym: homoiology
comment: Used for structures in distantly related taxa.

Axiom
annotated source: in deep homology relationship with
annotated property: definition
annotated target: Homocracy that involves morphologically and phylogenetically disparate structures that are the result of parallel evolution.
database_cross_reference: http://dx.doi.org/10.1007/BF02814485
database_cross_reference: nature07891
database_cross_reference: HOM_0000044

in hemiplasy relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that is characterized by topological discordance between a gene tree and a species tree attributable to the phylogenetic sorting of genetic polymorphisms across successive nodes in a species tree.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: hemiplasous to

Axiom
annotated source: in hemiplasy relationship with
annotated property: definition
annotated target: Historical homology that is characterized by topological discordance between a gene tree and a species tree attributable to the phylogenetic sorting of genetic polymorphisms across successive nodes in a species tree.
database_cross_reference: pnas.0807433105
database_cross_reference: HOM_0000045

in gametology relationship with
type: ObjectProperty
sub property of: in chromosomal homology relationship with
type: SymmetricProperty
definition: Historical homology that involves not recombining and subsequently differentiated sex chromosomes.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: gametologous to

Axiom
annotated source: in gametology relationship with
annotated property: definition
annotated target: Historical homology that involves not recombining and subsequently differentiated sex chromosomes.
database_cross_reference: HOM_0000046
database_cross_reference: http://www.ncbi.nlm.nih.gov/pubmed/11110898

in chromosomal homology relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that involves the chromosomes able to pair (synapse) during meiosis.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: MeSH:Chromosome_Pairing
has_exact_synonym: chromosomal homologous to

Axiom
annotated source: in chromosomal homology relationship with
annotated property: definition
annotated target: Historical homology that involves the chromosomes able to pair (synapse) during meiosis.
database_cross_reference: HOM_0000047
database_cross_reference: ISBN:0195307615

in many to many orthology relationship with
type: ObjectProperty
sub property of: in orthology relationship with
sub property of: in many to many homology relationship with
type: SymmetricProperty
definition: Orthology that involves two genes that experienced duplications more recent than the species split that created them.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: many to many orthologous to
has_exact_synonym: many-to-many orthology
has_exact_synonym: many:many orthology
has_exact_synonym: trans-orthology
has_related_synonym: co-orthology
has_related_synonym: trans-homology

Axiom
annotated source: in many to many orthology relationship with
annotated property: definition
annotated target: Orthology that involves two genes that experienced duplications more recent than the species split that created them.
database_cross_reference: 415741a
database_cross_reference: HOM_0000048
database_cross_reference: homology method.html

in within-species paralogy relationship with
type: ObjectProperty
sub property of: in paralogy relationship with
type: SymmetricProperty
property disjoint with: in between-species paralogy relationship with
definition: Paralogy that involves genes from the same species.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: within-species paralogous to

Axiom
annotated source: in within-species paralogy relationship with
annotated property: definition
annotated target: Paralogy that involves genes from the same species.
database_cross_reference: HOM_0000049
database_cross_reference: homology method.html

in between-species paralogy relationship with
type: ObjectProperty
sub property of: in paralogy relationship with
type: SymmetricProperty
definition: Paralogy that involves genes from different species.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: between-species paralogous to
comment: The genes have diverged before a speciation event.

Axiom
annotated source: in between-species paralogy relationship with
annotated property: definition
annotated target: Paralogy that involves genes from different species.
database_cross_reference: HOM_0000050
database_cross_reference: homology method.html

in postdisplacement relationship with
type: ObjectProperty
sub property of: in paedomorphorsis relationship with
type: SymmetricProperty
definition: Paedomorphosis that is produced by delayed growth of immature structures into the adult form.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: post-displacement

Axiom
annotated source: in postdisplacement relationship with
annotated property: definition
annotated target: Paedomorphosis that is produced by delayed growth of immature structures into the adult form.
database_cross_reference: Pedomorphosis
database_cross_reference: HOM_0000051

in hypermorphosis relationship with
type: ObjectProperty
sub property of: in peramorphosis relationship with
type: SymmetricProperty
definition: Peramorphosis that is produced by a delay in the offset of development.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127

Axiom
annotated source: in hypermorphosis relationship with
annotated property: definition
annotated target: Peramorphosis that is produced by a delay in the offset of development.
database_cross_reference: Peramorphosis
database_cross_reference: HOM_0000052
database_cross_reference: ISBN:978-0674639416

in synology relationship with
type: ObjectProperty
sub property of: in xenology relationship with
type: SymmetricProperty
definition: Xenology that results, not from the transfer of a gene between two species, but from a hybridization of two species.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: synologous to

Axiom
annotated source: in synology relationship with
annotated property: definition
annotated target: Xenology that results, not from the transfer of a gene between two species, but from a hybridization of two species.
database_cross_reference: http://dx.doi.org/10.1007/BF00173425
database_cross_reference: S0168-9525(00)02005-9
database_cross_reference: HOM_0000053

in isoorthology relationship with
type: ObjectProperty
sub property of: in orthology relationship with
sub property of: in equivalogy relationship with
type: SymmetricProperty
definition: Orthology that involves functional equivalent genes with retention of the ancestral function.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
database_cross_reference: ECO:0000080
has_exact_synonym: isoorthologous to

Axiom
annotated source: in isoorthology relationship with
annotated property: definition
annotated target: Orthology that involves functional equivalent genes with retention of the ancestral function.
database_cross_reference: S0168-9525(00)02005-9
database_cross_reference: HOM_0000054

in tandem paralogy relationship with
type: ObjectProperty
sub property of: in paralogy relationship with
type: SymmetricProperty
definition: Paralogy that is characterized by duplication of adjacent sequences on a chromosome segment.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: tandem paralogous to
has_related_synonym: iterative paralogy
has_related_synonym: serial paralogy

Axiom
annotated source: in tandem paralogy relationship with
annotated property: definition
annotated target: Paralogy that is characterized by duplication of adjacent sequences on a chromosome segment.
database_cross_reference: S0168-9525(00)02005-9
database_cross_reference: HOM_0000055
database_cross_reference: ISBN:978-0878932665

in latent homology relationship with
type: ObjectProperty
sub property of: in parallelism relationship with
sub property of: in syngeny relationship with
type: SymmetricProperty
definition: Parallelism that involves morphologically very similar structures, occurring only within some members of a taxon and absent in the common ancestor (which possessed the developmental basis to develop this character).
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: apomorphic tendency
has_exact_synonym: cryptic homology
has_exact_synonym: latent homologous to
has_exact_synonym: underlying synapomorphy
has_related_synonym: homoiology
has_related_synonym: homoplastic tendency
has_related_synonym: re-awakening
comment: Used for structures in closely related taxa.

Axiom
annotated source: in latent homology relationship with
annotated property: definition
annotated target: Parallelism that involves morphologically very similar structures, occurring only within some members of a taxon and absent in the common ancestor (which possessed the developmental basis to develop this character).
database_cross_reference: http://dx.doi.org/10.1007/BF02814485
database_cross_reference: j.jhevol.2006.11.010
database_cross_reference: http://dx.doi.org/10.1186/1742-9994-2-15
database_cross_reference: HOM_0000057
database_cross_reference: ISBN:0199141118

in syngeny relationship with
type: ObjectProperty
sub property of: in homocracy relationship with
type: SymmetricProperty
definition: Homocracy that involves recognizably corresponding characters that occurs in two or more taxa, or as a repeated unit within an individual.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: generative homology
has_exact_synonym: syngenous to
comment: Cannot be used when orthologous patterning gene are organizing obviously non-homologous structures in different organisms due for example to pleiotropic functions of these genes.

Axiom
annotated source: in syngeny relationship with
annotated property: definition
annotated target: Homocracy that involves recognizably corresponding characters that occurs in two or more taxa, or as a repeated unit within an individual.
database_cross_reference: http://dx.doi.org/10.1186/1742-9994-2-15
database_cross_reference: HOM_0000058
database_cross_reference: DOI:10.1002/1521-1878(200009)22:9<846::AID-BIES10>3.0.CO;2-R

in apparent orthology relationship with
type: ObjectProperty
sub property of: in 1 to 1 homology relationship with
sub property of: in between-species paralogy relationship with
type: SymmetricProperty
definition: Between-species paralogy that involves single copy paralogs resulting from reciprocal gene loss.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: 1:1 paralogy
has_exact_synonym: apparent 1:1 orthology
has_exact_synonym: apparent orthologous to
has_exact_synonym: pseudoorthology
comment: The genes are actually paralogs but appear to be orthologous due to differential, lineage-specific gene loss.

Axiom
annotated source: in apparent orthology relationship with
annotated property: definition
annotated target: Between-species paralogy that involves single copy paralogs resulting from reciprocal gene loss.
database_cross_reference: annurev.genet.39.073003.114725
database_cross_reference: HOM_0000060
database_cross_reference: homology method.html

in pseudoparalogy relationship with
type: ObjectProperty
sub property of: in xenology relationship with
type: SymmetricProperty
definition: Xenology that involves genes that ended up in a given genome as a result of a combination of vertical inheritance and horizontal gene transfer.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: pseudoparalogous to
comment: These genes may come out as paralogs in a single-genome analysis.

Axiom
annotated source: in pseudoparalogy relationship with
annotated property: definition
annotated target: Xenology that involves genes that ended up in a given genome as a result of a combination of vertical inheritance and horizontal gene transfer.
database_cross_reference: annurev.genet.39.073003.114725
database_cross_reference: HOM_0000061

in equivalogy relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
sub property of: in functional equivalence relationship with
type: SymmetricProperty
definition: Historical homology that involves functional equivalent genes with retention of the ancestral function.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: equivalogous to
comment: This may include examples of orthology, paralogy and xenology.

Axiom
annotated source: in equivalogy relationship with
annotated property: definition
annotated target: Historical homology that involves functional equivalent genes with retention of the ancestral function.
database_cross_reference: gkl1043
database_cross_reference: HOM_0000062

in interology relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that involves orthologous pairs of interacting molecules in different organisms.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: interologous to

Axiom
annotated source: in interology relationship with
annotated property: definition
annotated target: Historical homology that involves orthologous pairs of interacting molecules in different organisms.
database_cross_reference: gr.1774904
database_cross_reference: science.287.5450.116
database_cross_reference: HOM_0000063

in functional equivalence relationship with
type: ObjectProperty
sub property of: in similarity relationship with
type: SymmetricProperty
definition: Similarity that is characterized by interchangeability in function.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_related_synonym: functional similarity

Axiom
annotated source: in functional equivalence relationship with
annotated property: definition
annotated target: Similarity that is characterized by interchangeability in function.
database_cross_reference: http://dx.doi.org/10.1007/BF02814484
database_cross_reference: 415741a
database_cross_reference: HOM_0000065

in iterative homology relationship with
type: ObjectProperty
sub property of: in biological homology relationship with
type: SymmetricProperty
definition: Biological homology that involves parts of the same organism.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: iterative homologous to

Axiom
annotated source: in iterative homology relationship with
annotated property: definition
annotated target: Biological homology that involves parts of the same organism.
database_cross_reference: annurev.es.20.110189.000411
database_cross_reference: HOM_0000066

in paraxenology relationship with
type: ObjectProperty
sub property of: in xenology relationship with
type: SymmetricProperty
definition: Xenology that is characterized by multiple horizontal transfer events, resulting in the presence of two or more copies of the foreign gene in the host genome.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: duplicate xenology
has_exact_synonym: multiple xenology
has_exact_synonym: paraxenologous to

Axiom
annotated source: in paraxenology relationship with
annotated property: definition
annotated target: Xenology that is characterized by multiple horizontal transfer events, resulting in the presence of two or more copies of the foreign gene in the host genome.
database_cross_reference: HOM_0000068
database_cross_reference: http://www.ncbi.nlm.nih.gov/pubmed/3065587

in plerology relationship with
type: ObjectProperty
sub property of: in paralogy relationship with
type: SymmetricProperty
definition: Paralogy that is characterized by extra similarity between paralogous sequences resulting from concerted evolution.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: plerologous to
comment: This phenomenon is usually due to gene conversion process.

Axiom
annotated source: in plerology relationship with
annotated property: definition
annotated target: Paralogy that is characterized by extra similarity between paralogous sequences resulting from concerted evolution.
database_cross_reference: HOM_0000069
database_cross_reference: http://www.ncbi.nlm.nih.gov/pubmed/3065587

in homotopy relationship with
type: ObjectProperty
sub property of: in structural homology relationship with
type: SymmetricProperty
property disjoint with: in homeosis relationship with
definition: Structural homology that involves structures with the same or similar relative positions.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: homotopous to
comment: Theissen (2005) mentions that some authors may consider homotopy to be distinct from homology, but this is not the standard use.

Axiom
annotated source: in homotopy relationship with
annotated property: definition
annotated target: Structural homology that involves structures with the same or similar relative positions.
database_cross_reference: http://dx.doi.org/10.1007/BF02814484
database_cross_reference: http://dx.doi.org/10.1007/BF02814485
database_cross_reference: HOM_0000071
database_cross_reference: ISBN:0123195837

in homeosis relationship with
type: ObjectProperty
sub property of: in biological homology relationship with
type: SymmetricProperty
definition: Biological homology that involves an ectopic structure and the normally positioned structure.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_related_synonym: heterotopy

Axiom
annotated source: in homeosis relationship with
annotated property: definition
annotated target: Biological homology that involves an ectopic structure and the normally positioned structure.
database_cross_reference: http://dx.doi.org/10.1007/BF02814485
database_cross_reference: j.cell.2008.06.030
database_cross_reference: HOM_0000072

in homoeology relationship with
type: ObjectProperty
sub property of: in ohnology relationship with
sub property of: in synology relationship with
type: SymmetricProperty
definition: Synology that results from allopolyploidy.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: homoeologous to
comment: On a long term, it is hard to distinguish allopolyploidy from whole genome duplication.

Axiom
annotated source: in homoeology relationship with
annotated property: definition
annotated target: Synology that results from allopolyploidy.
database_cross_reference: pnas.0505156102
database_cross_reference: HOM_0000073

in paramorphism relationship with
type: ObjectProperty
sub property of: in homocracy relationship with
sub property of: in iterative homology relationship with
type: SymmetricProperty
definition: Iterative homology that involves two structures, one of which originated as a duplicate of the other and co-opted the expression of patterning genes of the ancestral structure.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_related_synonym: axis paramorphism

Axiom
annotated source: in paramorphism relationship with
annotated property: definition
annotated target: Iterative homology that involves two structures, one of which originated as a duplicate of the other and co-opted the expression of patterning genes of the ancestral structure.
database_cross_reference: s10441-007-9023-8
database_cross_reference: j.1525-142x.2000.00054.x
database_cross_reference: HOM_0000074

in regulogy relationship with
type: ObjectProperty
sub property of: in historical homology relationship with
type: SymmetricProperty
definition: Historical homology that involves orthologous pairs of transcription factors and downstream regulated genes in different organisms.
creator: bgee.unil.ch
source: http://www.ncbi.nlm.nih.gov/pubmed/20116127
has_exact_synonym: regulogous to

Axiom
annotated source: in regulogy relationship with
annotated property: definition
annotated target: Historical homology that involves orthologous pairs of transcription factors and downstream regulated genes in different organisms.
database_cross_reference: gr.1774904
database_cross_reference: HOM_0000075

anteriorly connected to
type: ObjectProperty
sub property of: posterior to
sub property of: connected to
sub property of: transitively anteriorly connected to
definition: x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y.
has_obo_namespace: uberon
id: anteriorly_connected_to

Axiom
annotated source: anteriorly connected to
annotated property: definition
annotated target: x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

channel for
type: ObjectProperty
domain: UBERON_0004111
range: UBERON_0000463
has_broad_synonym: carries
has_obo_namespace: uberon
id: channel_for

channels_from
type: ObjectProperty
type: TransitiveProperty
has_obo_namespace: uberon
id: channels_from

channels_into
type: ObjectProperty
type: TransitiveProperty
has_obo_namespace: uberon
id: channels_into

distally connected to
type: ObjectProperty
sub property of: proximal to
sub property of: connected to
sub property of: transitively distally connected to
inverse of: proximally connected to
definition: x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y.
has_obo_namespace: uberon
id: distally_connected_to

Axiom
annotated source: distally connected to
annotated property: definition
annotated target: x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

extends_fibers_into
type: ObjectProperty
sub property of: connected to
type: SymmetricProperty
definition: X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y
has_obo_namespace: uberon
id: extends_fibers_into

Axiom
annotated source: extends_fibers_into
annotated property: definition
annotated target: X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y
database_cross_reference: https://orcid.org/0000-0002-7073-9172

filtered through
type: ObjectProperty
definition: Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity.
has_obo_namespace: uberon
id: filtered_through
comment: Relationship between a fluid and a filtration barrier, where the portion of fluid arises as a transformation of another portion of fluid on the other side of the barrier, with larger particles removed

indirectly_supplies
type: ObjectProperty
type: TransitiveProperty
property chain axiom: has branching part
property chain axiom: supplies
definition: a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s.
editor note: add to RO
has_obo_namespace: uberon
id: indirectly_supplies

layer part of
type: ObjectProperty
sub property of: part of
has_obo_namespace: uberon
id: layer_part_of

posteriorly connected to
type: ObjectProperty
sub property of: anterior to
sub property of: connected to
definition: x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y.
has_obo_namespace: uberon
id: posteriorly_connected_to

Axiom
annotated source: posteriorly connected to
annotated property: definition
annotated target: x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

protects
type: ObjectProperty
has_obo_namespace: uberon
id: protects

proximally connected to
type: ObjectProperty
sub property of: distal to
sub property of: connected to
sub property of: transitively proximally connected to
definition: x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y.
has_obo_namespace: uberon
id: proximally_connected_to

Axiom
annotated source: proximally connected to
annotated property: definition
annotated target: x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y.
database_cross_reference: http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern

site_of
type: ObjectProperty
definition: c site_of p if c is the bearer of a disposition that is realized by a process that has p as part.
has_obo_namespace: uberon
has_related_synonym: capable_of_has_part
id: site_of

subdivision of
type: ObjectProperty
has_obo_namespace: uberon
id: subdivision_of
comment: placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B

transitively anteriorly connected to
type: ObjectProperty
type: TransitiveProperty
has_obo_namespace: uberon
id: transitively_anteriorly_connected_to

transitively distally connected to
type: ObjectProperty
type: TransitiveProperty
has_obo_namespace: uberon
id: transitively_distally_connected_to

transitively proximally connected to
type: ObjectProperty
type: TransitiveProperty
has_obo_namespace: uberon
id: transitively_proximally_connected_to

has increased age-specific mortality rate
type: DatatypeProperty
range: Datatype
  on datatype: short
  with restrictions:
    min inclusive: 0
  with restrictions:
    max inclusive: 100
definition: Then percentage of organisms in a population that die during some specified age range (age-specific mortality rate), minus the percentage that die in during the same age range in a wild-type population.
created by: https://orcid.org/0000-0002-7073-9172
creation date: 2018-05-22T16:43:28Z
comment: This could be used to record the increased infant morality rate in some population compared to wild-type. For examples of usage see http://purl.obolibrary.org/obo/FBcv_0000351 and subclasses.

Axiom
annotated source: has increased age-specific mortality rate
annotated property: definition
annotated target: Then percentage of organisms in a population that die during some specified age range (age-specific mortality rate), minus the percentage that die in during the same age range in a wild-type population.
database_cross_reference: PMID:24138933
database_cross_reference: Wikipedia:Infant_mortality

entity
type: Class
BFO_0000179: entity
BFO_0000180: Entity
example of usage: Julius Caesar
example of usage: Verdi’s Requiem
example of usage: the Second World War
example of usage: your body mass index
editor note: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
editor note: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
elucidation: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])

Axiom
annotated source: entity
annotated property: editor note
annotated target: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000004
comment: per discussion with Barry Smith

Axiom
annotated source: entity
annotated property: elucidation
annotated target: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/001-001

continuant
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: continuant
subclass of: Restriction
  on property: has prototype
  all values from: continuant
subclass of: Restriction
  on property: in similarity relationship with
  all values from: continuant
disjoint with: occurrent
disjoint with: Restriction
  on property: part of
  some values from: occurrent
BFO_0000179: continuant
BFO_0000180: Continuant
definition: An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
editor note: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
editor note: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
elucidation: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
has associated axiom(nl): if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has associated axiom(nl): if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has associated axiom(nl): if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has associated axiom(fol): (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
has associated axiom(fol): (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]

Axiom
annotated source: continuant
annotated property: editor note
annotated target: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000007

Axiom
annotated source: continuant
annotated property: elucidation
annotated target: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/011-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/011-002

occurrent
type: Class
subclass of: entity
subclass of: Restriction
  on property: part of
  all values from: occurrent
subclass of: Restriction
  on property: in similarity relationship with
  all values from: occurrent
disjoint with: Restriction
  on property: part of
  some values from: continuant
BFO_0000179: occurrent
BFO_0000180: Occurrent
definition: An entity that has temporal parts and that happens, unfolds or develops through time.
editor note: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region
editor note: BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.
editor note: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
editor note: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
OBO foundry unique label: processual entity (BFO)
elucidation: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
has associated axiom(nl): Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has associated axiom(nl): b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
has associated axiom(fol): (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
has associated axiom(fol): (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]

Axiom
annotated source: occurrent
annotated property: editor note
annotated target: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000006
comment: per discussion with Barry Smith

Axiom
annotated source: occurrent
annotated property: editor note
annotated target: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000012

Axiom
annotated source: occurrent
annotated property: elucidation
annotated target: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/077-002

Axiom
annotated source: occurrent
annotated property: has associated axiom(nl)
annotated target: Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(nl)
annotated target: b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/079-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/079-001

independent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: independent continuant
disjoint with: characteristic
disjoint with: generically dependent continuant
BFO_0000179: ic
BFO_0000180: IndependentContinuant
example of usage: a chair
example of usage: a heart
example of usage: a leg
example of usage: a molecule
example of usage: a spatial region
example of usage: an atom
example of usage: an orchestra.
example of usage: an organism
example of usage: the bottom right portion of a human torso
example of usage: the interior of your mouth
definition: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
definition: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
OBO foundry unique label: anatomical entity (BFO)
has associated axiom(nl): For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has associated axiom(nl): For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
has associated axiom(fol): (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
has associated axiom(fol): (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has associated axiom(fol): (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
comment: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.

Axiom
annotated source: independent continuant
annotated property: definition
annotated target: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/017-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(nl)
annotated target: For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: has associated axiom(nl)
annotated target: For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/017-002

spatial region
type: Class
subclass of: immaterial entity
disjoint with: site
disjoint with: continuant fiat boundary
BFO_0000179: s-region
BFO_0000180: SpatialRegion
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
editor note: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
elucidation: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has associated axiom(nl): All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
has associated axiom(fol): (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
has associated axiom(fol): (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]

Axiom
annotated source: spatial region
annotated property: editor note
annotated target: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000002
comment: per discussion with Barry Smith

Axiom
annotated source: spatial region
annotated property: elucidation
annotated target: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/035-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(nl)
annotated target: All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/035-001

temporal region
type: Class
subclass of: occurrent
disjoint with: spatiotemporal region
disjoint with: process
disjoint with: process boundary

spatiotemporal region
type: Class
subclass of: occurrent

process
type: Class
subclass of: occurrent
subclass of: Restriction
  on property: part of
  all values from: process
subclass of: Restriction
  on property: has prototype
  all values from: process
BFO_0000179: process
BFO_0000180: Process
example of usage: a process of cell-division, \ a beating of the heart
example of usage: a process of meiosis
example of usage: a process of sleeping
example of usage: the course of a disease
example of usage: the flight of a bird
example of usage: the life of an organism
example of usage: your process of aging.
definition: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
editor note: BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)
has associated axiom(fol): (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]
comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.

Axiom
annotated source: process
annotated property: definition
annotated target: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/083-003

Axiom
annotated source: process
annotated property: has associated axiom(fol)
annotated target: (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/083-003

disposition
type: Class
subclass of: realizable
disjoint with: role
BFO_0000179: disposition
BFO_0000180: Disposition
example of usage: an atom of element X has the disposition to decay to an atom of element Y
example of usage: certain people have a predisposition to colon cancer
example of usage: children are innately disposed to categorize objects in certain ways.
example of usage: the cell wall is disposed to filter chemicals in endocytosis and exocytosis
editor note: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.
elucidation: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
has associated axiom(nl): If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
has associated axiom(fol): (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
has associated axiom(fol): (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]

Axiom
annotated source: disposition
annotated property: elucidation
annotated target: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/062-002

Axiom
annotated source: disposition
annotated property: has associated axiom(nl)
annotated target: If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/062-002

realizable
type: Class
subclass of: characteristic
subclass of: Restriction
  on property: part of
  all values from: realizable
disjoint with: quality
BFO_0000179: realizable
BFO_0000180: RealizableEntity
example of usage: the disposition of this piece of metal to conduct electricity.
example of usage: the disposition of your blood to coagulate
example of usage: the function of your reproductive organs
example of usage: the role of being a doctor
example of usage: the role of this boundary to delineate where Utah and Colorado meet
definition: A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
elucidation: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
has associated axiom(nl): All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
has associated axiom(fol): (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
has associated axiom(fol): (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]
label: realizable entity

Axiom
annotated source: realizable
annotated property: elucidation
annotated target: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/058-002

Axiom
annotated source: realizable
annotated property: has associated axiom(nl)
annotated target: All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/058-002

quality
type: Class
subclass of: characteristic
subclass of: Restriction
  on property: part of
  all values from: quality
BFO_0000179: quality
BFO_0000180: Quality
example of usage: the ambient temperature of this portion of air
example of usage: the color of a tomato
example of usage: the length of the circumference of your waist
example of usage: the mass of this piece of gold.
example of usage: the shape of your nose
example of usage: the shape of your nostril
elucidation: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
has associated axiom(nl): If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
has associated axiom(fol): (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
has associated axiom(fol): (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]

Axiom
annotated source: quality
annotated property: elucidation
annotated target: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: has associated axiom(nl)
annotated target: If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/105-001

Axiom
annotated source: quality
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/105-001

characteristic
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: characteristic
subclass of: Restriction
  on property: has part
  all values from: characteristic
disjoint with: generically dependent continuant
BFO_0000179: sdc
BFO_0000180: SpecificallyDependentContinuant
example of usage: Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
example of usage: of one-sided specifically dependent continuants: the mass of this tomato
example of usage: of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
example of usage: the disposition of this fish to decay
example of usage: the function of this heart: to pump blood
example of usage: the mutual dependence of proton donors and acceptors in chemical reactions [79
example of usage: the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
example of usage: the pink color of a medium rare piece of grilled filet mignon at its center
example of usage: the role of being a doctor
example of usage: the shape of this hole.
example of usage: the smell of this portion of mozzarella
definition: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
definition: b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
definition: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
editor note: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
has associated axiom(fol): (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
label: specifically dependent continuant

Axiom
annotated source: characteristic
annotated property: definition
annotated target: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/050-003

Axiom
annotated source: characteristic
annotated property: editor note
annotated target: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000005
comment: per discussion with Barry Smith

Axiom
annotated source: characteristic
annotated property: has associated axiom(fol)
annotated target: (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/050-003

role
type: Class
subclass of: realizable
BFO_0000179: role
BFO_0000180: Role
example of usage: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
example of usage: the priest role
example of usage: the role of a boundary to demarcate two neighboring administrative territories
example of usage: the role of a building in serving as a military target
example of usage: the role of a stone in marking a property boundary
example of usage: the role of subject in a clinical trial
example of usage: the student role
definition: A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
editor note: BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.
elucidation: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
has associated axiom(fol): (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]

Axiom
annotated source: role
annotated property: elucidation
annotated target: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/061-001

Axiom
annotated source: role
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/061-001

fiat object
type: Class
subclass of: material entity
label: fiat object part

object aggregate
type: Class
subclass of: material entity

site
type: Class
subclass of: immaterial entity

object
type: Class
subclass of: material entity

generically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of
  all values from: generically dependent continuant
BFO_0000179: gdc
BFO_0000180: GenericallyDependentContinuant
example of usage: The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.
example of usage: the pdf file on your laptop, the pdf file that is a copy thereof on my laptop
example of usage: the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.
definition: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
definition: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
has associated axiom(fol): (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
comment: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.

Axiom
annotated source: generically dependent continuant
annotated property: definition
annotated target: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/074-001

Axiom
annotated source: generically dependent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/074-001

function
type: Class
subclass of: disposition
BFO_0000179: function
BFO_0000180: Function
example of usage: the function of a hammer to drive in nails
example of usage: the function of a heart pacemaker to regulate the beating of a heart through electricity
example of usage: the function of amylase in saliva to break down starch into sugar
editor note: BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.
elucidation: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
has associated axiom(fol): (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]

Axiom
annotated source: function
annotated property: elucidation
annotated target: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/064-001

Axiom
annotated source: function
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/064-001

process boundary
type: Class
subclass of: occurrent
definition: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])

Axiom
annotated source: process boundary
annotated property: definition
annotated target: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/084-001

one-dimensional temporal region
type: Class
subclass of: temporal region

material entity
type: Class
subclass of: independent continuant
disjoint with: immaterial entity
disjoint with: Restriction
  on property: part of
  some values from: immaterial entity
BFO_0000179: material
BFO_0000180: MaterialEntity
example of usage: a flame
example of usage: a forest fire
example of usage: a human being
example of usage: a hurricane
example of usage: a photon
example of usage: a puff of smoke
example of usage: a sea wave
example of usage: a tornado
example of usage: an aggregate of human beings.
example of usage: an energy wave
example of usage: an epidemic
example of usage: the undetached arm of a human being
definition: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
editor note: BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
editor note: BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
editor note: BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
elucidation: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
has associated axiom(nl): Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
has associated axiom(nl): every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
has associated axiom(fol): (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]

Axiom
annotated source: material entity
annotated property: elucidation
annotated target: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: has associated axiom(nl)
annotated target: Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/020-002

Axiom
annotated source: material entity
annotated property: has associated axiom(nl)
annotated target: every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/020-002

continuant fiat boundary
type: Class
subclass of: immaterial entity
definition: b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])

Axiom
annotated source: continuant fiat boundary
annotated property: definition
annotated target: b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/029-001

immaterial entity
type: Class
subclass of: independent continuant
disjoint with: Restriction
  on property: has part
  some values from: material entity
BFO_0000179: immaterial
BFO_0000180: ImmaterialEntity
editor note: BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10

one-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary
disjoint with: two-dimensional continuant fiat boundary

two-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary

electron
type: Class
subclass of: lepton
definition: Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
charge: -1
mass: 0.000548579903
monoisotopicmass: 0.0
database_cross_reference: KEGG:C05359
database_cross_reference: PMID:21614077
database_cross_reference: Wikipedia:Electron
has_exact_synonym: electron
has_obo_namespace: chebi_ontology
has_related_synonym: Elektron
has_related_synonym: beta
has_related_synonym: beta(-)
has_related_synonym: beta-particle
has_related_synonym: e
has_related_synonym: e(-)
has_related_synonym: e-
has_related_synonym: negatron
id: CHEBI:10545
in_subset: 3 STAR

Axiom
annotated source: electron
annotated property: database_cross_reference
annotated target: PMID:21614077
source: Europe PMC

Axiom
annotated source: electron
annotated property: has_exact_synonym
annotated target: electron
database_cross_reference: ChEBI

Axiom
annotated source: electron
annotated property: has_exact_synonym
annotated target: electron
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: electron
annotated property: has_exact_synonym
annotated target: electron
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: Elektron
database_cross_reference: ChEBI

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: beta
database_cross_reference: IUPAC

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: beta(-)
database_cross_reference: ChEBI

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: beta-particle
database_cross_reference: IUPAC

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: e
database_cross_reference: IUPAC

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: e(-)
database_cross_reference: UniProt

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: e-
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: electron
annotated property: has_related_synonym
annotated target: negatron
database_cross_reference: IUPAC

C19-steroid
type: Class
subclass of: steroid

dicarboxylic acids and O-substituted derivatives
type: Class
subclass of: carbonyl compound
definition: A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens.
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboxylic acids and derivatives
id: CHEBI:131927
in_subset: 3 STAR

Axiom
annotated source: dicarboxylic acids and O-substituted derivatives
annotated property: has_related_synonym
annotated target: dicarboxylic acids and derivatives
database_cross_reference: ChEBI

hyaluronate
type: Class
subclass of: polyanionic polymer
subclass of: carbohydrate acid derivative anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: hyaluronic acid
definition: A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3.
charge: -1
formula: (C14H20NO11)n.H2O
has_obo_namespace: chebi_ontology
has_related_synonym: hyaluronan
has_related_synonym: hyaluronate polyanion
id: CHEBI:132153
in_subset: 3 STAR

Axiom
annotated source: hyaluronate
annotated property: has_related_synonym
annotated target: hyaluronan
database_cross_reference: UniProt

Axiom
annotated source: hyaluronate
annotated property: has_related_synonym
annotated target: hyaluronate polyanion
database_cross_reference: ChEBI

metal oxide
type: Class
subclass of: inorganic oxide

NAD
type: Class
subclass of: NAD(P)

NAD(P)H
type: Class
subclass of: NAD(P)

chlorofluorocarbon
type: Class
subclass of: volatile organic compound
subclass of: organochlorine compound
subclass of: organofluorine compound

volatile organic compound
type: Class
subclass of: organic molecule

titanium oxides
type: Class
subclass of: titanium molecular entity

glycol
type: Class
subclass of: diol

pyrrolopurine
type: Class
subclass of: organic heterotricyclic compound
subclass of: organonitrogen heterocyclic compound

5beta steroid
type: Class
subclass of: steroid
definition: Any steroid that has beta-configuration at position 5.
has_obo_namespace: chebi_ontology
has_related_synonym: 5beta steroids
has_related_synonym: 5beta-steroid
has_related_synonym: 5beta-steroids
id: CHEBI:136889
in_subset: 3 STAR

Axiom
annotated source: 5beta steroid
annotated property: has_related_synonym
annotated target: 5beta steroids
database_cross_reference: ChEBI

Axiom
annotated source: 5beta steroid
annotated property: has_related_synonym
annotated target: 5beta-steroid
database_cross_reference: ChEBI

Axiom
annotated source: 5beta steroid
annotated property: has_related_synonym
annotated target: 5beta-steroids
database_cross_reference: ChEBI

metalloid atom
type: Class
subclass of: atom

inorganic acid
type: Class
subclass of: Bronsted acid
definition: A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
database_cross_reference: Wikipedia:Mineral_acid
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic acids
has_related_synonym: mineral acid
has_related_synonym: mineral acids
id: CHEBI:138103
in_subset: 3 STAR

Axiom
annotated source: inorganic acid
annotated property: has_related_synonym
annotated target: inorganic acids
database_cross_reference: ChEBI

Axiom
annotated source: inorganic acid
annotated property: has_related_synonym
annotated target: mineral acid
database_cross_reference: ChEBI

Axiom
annotated source: inorganic acid
annotated property: has_related_synonym
annotated target: mineral acids
database_cross_reference: ChEBI

bile acids
type: Class
subclass of: monocarboxylic acid
subclass of: hydroxy steroid
subclass of: cholanoid
definition: Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration.
has_obo_namespace: chebi_ontology
id: CHEBI:138366
in_subset: 3 STAR

gas molecular entity
type: Class
subclass of: main group molecular entity
definition: Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/Gas
has_obo_namespace: chebi_ontology
has_related_synonym: gas molecular entities
has_related_synonym: gaseous molecular entities
has_related_synonym: gaseous molecular entity
id: CHEBI:138675
in_subset: 3 STAR

Axiom
annotated source: gas molecular entity
annotated property: has_related_synonym
annotated target: gas molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: gas molecular entity
annotated property: has_related_synonym
annotated target: gaseous molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: gas molecular entity
annotated property: has_related_synonym
annotated target: gaseous molecular entity
database_cross_reference: ChEBI

carotenoid beta-end derivative
type: Class
subclass of: carotenoid

chlorophyll(1-)
type: Class
subclass of: cyclic tetrapyrrole anion

chlorophyllide(2-)
type: Class
subclass of: monocarboxylic acid anion
subclass of: cyclic tetrapyrrole anion

carbamate
type: Class
subclass of: amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbamic acid
charge: -1
formula: CH2NO2
inchi: InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1
inchikey: KXDHJXZQYSOELW-UHFFFAOYSA-M
mass: 60.03212
monoisotopicmass: 60.00910
smiles: NC([O-])=O
database_cross_reference: Beilstein:3903503
database_cross_reference: CAS:302-11-4
database_cross_reference: Gmelin:239604
has_exact_synonym: carbamate
has_obo_namespace: chebi_ontology
has_related_synonym: Carbamat
has_related_synonym: Karbamat
has_related_synonym: carbamate ion
has_related_synonym: carbamic acid, ion(1-)
id: CHEBI:13941
in_subset: 3 STAR

Axiom
annotated source: carbamate
annotated property: database_cross_reference
annotated target: Beilstein:3903503
source: Beilstein

Axiom
annotated source: carbamate
annotated property: database_cross_reference
annotated target: CAS:302-11-4
source: ChemIDplus

Axiom
annotated source: carbamate
annotated property: database_cross_reference
annotated target: Gmelin:239604
source: Gmelin

Axiom
annotated source: carbamate
annotated property: has_exact_synonym
annotated target: carbamate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbamate
annotated property: has_exact_synonym
annotated target: carbamate
database_cross_reference: UniProt

Axiom
annotated source: carbamate
annotated property: has_related_synonym
annotated target: Carbamat
database_cross_reference: ChEBI

Axiom
annotated source: carbamate
annotated property: has_related_synonym
annotated target: Karbamat
database_cross_reference: ChEBI

Axiom
annotated source: carbamate
annotated property: has_related_synonym
annotated target: carbamate ion
database_cross_reference: ChemIDplus

Axiom
annotated source: carbamate
annotated property: has_related_synonym
annotated target: carbamic acid, ion(1-)
database_cross_reference: ChemIDplus

kaolin
type: Class
subclass of: aluminosilicate mineral
subclass of: mixture

24G7 epitope
type: Class
subclass of: independent continuant
subclass of: group
subclass of: Restriction
  on property: has role
  some values from: epitope
definition: An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22.
charge: 0
formula: C7H6N2O
mass: 134.136
monoisotopicmass: 134.04801
smiles: C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*
has_obo_namespace: chebi_ontology
id: CHEBI:142163
in_subset: 3 STAR

ultra-long-chain fatty acid
type: Class
subclass of: very long-chain fatty acid

ultra-long-chain fatty acid anion
type: Class
subclass of: very long-chain fatty acid anion

manganese dihydroxide
type: Class
subclass of: manganese hydroxide

manganese hydroxide
type: Class
subclass of: manganese molecular entity

electron donor
type: Class
subclass of: donor

acceptor
type: Class
subclass of: chemical role
definition: A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
has_alternative_id: CHEBI:13699
has_alternative_id: CHEBI:2377
database_cross_reference: KEGG:C00028
database_cross_reference: KEGG:C16722
has_exact_synonym: Acceptor
has_obo_namespace: chebi_ontology
has_related_synonym: A
has_related_synonym: Akzeptor
has_related_synonym: Hydrogen-acceptor
has_related_synonym: Oxidized donor
has_related_synonym: accepteur
id: CHEBI:15339
in_subset: 3 STAR

Axiom
annotated source: acceptor
annotated property: has_exact_synonym
annotated target: Acceptor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: has_related_synonym
annotated target: A
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: has_related_synonym
annotated target: Akzeptor
database_cross_reference: ChEBI

Axiom
annotated source: acceptor
annotated property: has_related_synonym
annotated target: Hydrogen-acceptor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: has_related_synonym
annotated target: Oxidized donor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acceptor
annotated property: has_related_synonym
annotated target: accepteur
database_cross_reference: ChEBI

acetylcholine
type: Class
subclass of: independent continuant
subclass of: acylcholine
subclass of: acetate ester
subclass of: Restriction
  on property: has role
  some values from: hormone
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: vasodilator agent
subclass of: Restriction
  on property: has role
  some values from: muscarinic agonist
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
definition: Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter.
charge: +1
formula: C7H16NO2
inchi: InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1
inchikey: OIPILFWXSMYKGL-UHFFFAOYSA-N
mass: 146.20748
monoisotopicmass: 146.11756
smiles: CC(=O)OCC[N+](C)(C)C
has_alternative_id: CHEBI:12686
has_alternative_id: CHEBI:13715
has_alternative_id: CHEBI:22197
has_alternative_id: CHEBI:2416
has_alternative_id: CHEBI:40559
database_cross_reference: Beilstein:1764436
database_cross_reference: CAS:51-84-3
database_cross_reference: DrugBank:DB03128
database_cross_reference: Drug_Central:65
database_cross_reference: Gmelin:326108
database_cross_reference: KEGG:C01996
database_cross_reference: LINCS:LSM-5888
database_cross_reference: PDBeChem:ACH
database_cross_reference: PMID:14764638
database_cross_reference: PMID:15014918
database_cross_reference: PMID:15231705
database_cross_reference: PMID:15361288
database_cross_reference: PMID:18050502
database_cross_reference: PMID:18407448
database_cross_reference: PMID:19255787
database_cross_reference: PMID:20963497
database_cross_reference: PMID:21130809
database_cross_reference: PMID:21246223
database_cross_reference: PMID:21545631
database_cross_reference: PMID:21601579
database_cross_reference: Wikipedia:Acetylcholine
has_exact_synonym: 2-acetyloxy-N,N,N-trimethylethanaminium
has_exact_synonym: ACETYLCHOLINE
has_exact_synonym: Acetylcholine
has_exact_synonym: acetylcholine
has_obo_namespace: chebi_ontology
has_related_synonym: ACh
has_related_synonym: Azetylcholin
has_related_synonym: O-Acetylcholine
has_related_synonym: choline acetate
id: CHEBI:15355
in_subset: 3 STAR

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: Beilstein:1764436
source: ChemIDplus

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: CAS:51-84-3
source: ChemIDplus

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: CAS:51-84-3
source: KEGG COMPOUND

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: Drug_Central:65
source: DrugCentral

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: Gmelin:326108
source: Gmelin

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:14764638
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:15014918
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:15231705
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:15361288
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:18050502
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:18407448
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:19255787
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:20963497
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21130809
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21246223
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21545631
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: database_cross_reference
annotated target: PMID:21601579
source: Europe PMC

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: 2-acetyloxy-N,N,N-trimethylethanaminium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: ACETYLCHOLINE
database_cross_reference: PDBeChem

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: Acetylcholine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetylcholine
annotated property: has_exact_synonym
annotated target: acetylcholine
database_cross_reference: UniProt

Axiom
annotated source: acetylcholine
annotated property: has_related_synonym
annotated target: ACh
database_cross_reference: ChemIDplus

Axiom
annotated source: acetylcholine
annotated property: has_related_synonym
annotated target: Azetylcholin
database_cross_reference: ChEBI

Axiom
annotated source: acetylcholine
annotated property: has_related_synonym
annotated target: O-Acetylcholine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetylcholine
annotated property: has_related_synonym
annotated target: choline acetate
database_cross_reference: ChemIDplus

acetic acid
type: Class
subclass of: monocarboxylic acid
subclass of: Restriction
  on property: has role
  some values from: protic solvent
subclass of: Restriction
  on property: has role
  some values from: food acidity regulator
subclass of: Restriction
  on property: has role
  some values from: antimicrobial food preservative
subclass of: Restriction
  on property: has role
  some values from: Daphnia magna metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: acetate
definition: A simple monocarboxylic acid containing two carbons.
charge: 0
formula: C2H4O2
inchi: InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
inchikey: QTBSBXVTEAMEQO-UHFFFAOYSA-N
mass: 60.05200
monoisotopicmass: 60.02113
smiles: CC(O)=O
has_alternative_id: CHEBI:22169
has_alternative_id: CHEBI:2387
has_alternative_id: CHEBI:40486
database_cross_reference: Beilstein:506007
database_cross_reference: CAS:64-19-7
database_cross_reference: Drug_Central:4211
database_cross_reference: Gmelin:1380
database_cross_reference: HMDB:HMDB0000042
database_cross_reference: KEGG:C00033
database_cross_reference: KEGG:D00010
database_cross_reference: KNApSAcK:C00001176
database_cross_reference: LIPID_MAPS_instance:LMFA01010002
database_cross_reference: MetaCyc:ACET
database_cross_reference: PDBeChem:ACT
database_cross_reference: PDBeChem:ACY
database_cross_reference: PMID:12005138
database_cross_reference: PMID:15107950
database_cross_reference: PMID:16630552
database_cross_reference: PMID:16774200
database_cross_reference: PMID:17190852
database_cross_reference: PMID:19416101
database_cross_reference: PMID:19469536
database_cross_reference: PMID:22153255
database_cross_reference: PMID:22173419
database_cross_reference: PPDB:1333
database_cross_reference: Reaxys:506007
database_cross_reference: Wikipedia:Acetic_acid
has_exact_synonym: ACETIC ACID
has_exact_synonym: Acetic acid
has_exact_synonym: acetic acid
has_obo_namespace: chebi_ontology
has_related_synonym: AcOH
has_related_synonym: CH3-COOH
has_related_synonym: CH3CO2H
has_related_synonym: E 260
has_related_synonym: E-260
has_related_synonym: E260
has_related_synonym: Essigsaeure
has_related_synonym: Ethanoic acid
has_related_synonym: Ethylic acid
has_related_synonym: HOAc
has_related_synonym: INS No. 260
has_related_synonym: MeCO2H
has_related_synonym: MeCOOH
has_related_synonym: Methanecarboxylic acid
has_related_synonym: acide acetique
has_related_synonym: ethoic acid
id: CHEBI:15366
in_subset: 3 STAR

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: Beilstein:506007
source: Beilstein

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: CAS:64-19-7
source: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: CAS:64-19-7
source: KEGG COMPOUND

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: CAS:64-19-7
source: NIST Chemistry WebBook

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: Drug_Central:4211
source: DrugCentral

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: Gmelin:1380
source: Gmelin

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: LIPID_MAPS_instance:LMFA01010002
source: LIPID MAPS

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:12005138
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:15107950
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:16630552
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:16774200
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:17190852
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:19416101
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:19469536
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:22153255
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: PMID:22173419
source: Europe PMC

Axiom
annotated source: acetic acid
annotated property: database_cross_reference
annotated target: Reaxys:506007
source: Reaxys

Axiom
annotated source: acetic acid
annotated property: has_exact_synonym
annotated target: ACETIC ACID
database_cross_reference: PDBeChem

Axiom
annotated source: acetic acid
annotated property: has_exact_synonym
annotated target: Acetic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetic acid
annotated property: has_exact_synonym
annotated target: acetic acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: AcOH
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: CH3-COOH
database_cross_reference: IUPAC

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: CH3CO2H
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: E 260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: E-260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: E260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: Essigsaeure
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: Ethanoic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: Ethylic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: HOAc
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: INS No. 260
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: MeCO2H
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: MeCOOH
database_cross_reference: ChEBI

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: Methanecarboxylic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: acide acetique
database_cross_reference: ChemIDplus

Axiom
annotated source: acetic acid
annotated property: has_related_synonym
annotated target: ethoic acid
database_cross_reference: ChEBI

acrolein
type: Class
subclass of: enal

water
type: Class
subclass of: oxygen hydride
subclass of: mononuclear parent hydride
subclass of: inorganic hydroxy compound

hydron
type: Class
subclass of: monoatomic monocation
subclass of: monoatomic hydrogen
subclass of: atomic nucleus
subclass of: monovalent inorganic cation

dioxygen
type: Class
subclass of: independent continuant
subclass of: gas molecular entity
subclass of: elemental molecule
subclass of: diatomic oxygen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: nutrient
subclass of: Restriction
  on property: has role
  some values from: reagent
subclass of: Restriction
  on property: has role
  some values from: anti-inflammatory drug
subclass of: Restriction
  on property: has role
  some values from: oxidising agent
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: has role
  some values from: food packaging gas
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydridodioxygen(1+)
charge: 0
formula: O2
inchi: InChI=1S/O2/c1-2
inchikey: MYMOFIZGZYHOMD-UHFFFAOYSA-N
mass: 31.998
monoisotopicmass: 31.98983
smiles: O=O
has_alternative_id: CHEBI:10745
has_alternative_id: CHEBI:13416
has_alternative_id: CHEBI:23833
has_alternative_id: CHEBI:25366
has_alternative_id: CHEBI:30491
has_alternative_id: CHEBI:44742
has_alternative_id: CHEBI:7860
database_cross_reference: CAS:7782-44-7
database_cross_reference: Gmelin:485
database_cross_reference: HMDB:HMDB0001377
database_cross_reference: KEGG:C00007
database_cross_reference: KEGG:D00003
database_cross_reference: MetaCyc:OXYGEN-MOLECULE
database_cross_reference: MolBase:750
database_cross_reference: PDBeChem:OXY
database_cross_reference: PMID:10906528
database_cross_reference: PMID:16977326
database_cross_reference: PMID:18210929
database_cross_reference: PMID:18638417
database_cross_reference: PMID:19840863
database_cross_reference: PMID:7710549
database_cross_reference: PMID:9463773
database_cross_reference: Wikipedia:Oxygen
has_exact_synonym: dioxygen
has_obo_namespace: chebi_ontology
has_related_synonym: Disauerstoff
has_related_synonym: E 948
has_related_synonym: E-948
has_related_synonym: E948
has_related_synonym: O2
has_related_synonym: OXYGEN MOLECULE
has_related_synonym: Oxygen
has_related_synonym: [OO]
has_related_synonym: dioxygene
has_related_synonym: molecular oxygen
id: CHEBI:15379
in_subset: 3 STAR

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: CAS:7782-44-7
source: ChemIDplus

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: CAS:7782-44-7
source: KEGG COMPOUND

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: CAS:7782-44-7
source: NIST Chemistry WebBook

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: Gmelin:485
source: Gmelin

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:10906528
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:16977326
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:18210929
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:18638417
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:19840863
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:7710549
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: database_cross_reference
annotated target: PMID:9463773
source: Europe PMC

Axiom
annotated source: dioxygen
annotated property: has_exact_synonym
annotated target: dioxygen
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: Disauerstoff
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: E 948
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: E-948
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: E948
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: O2
database_cross_reference: IUPAC

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: O2
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: O2
database_cross_reference: UniProt

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: OXYGEN MOLECULE
database_cross_reference: PDBeChem

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: Oxygen
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: [OO]
database_cross_reference: MolBase

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: dioxygene
database_cross_reference: ChEBI

Axiom
annotated source: dioxygen
annotated property: has_related_synonym
annotated target: molecular oxygen
database_cross_reference: ChEBI

ATP
type: Class
subclass of: purine ribonucleoside 5'-triphosphate
subclass of: adenosine 5'-phosphate

argon-39 atom
type: Class
subclass of: argon atom

copper(II) phthalocyanine
type: Class
subclass of: copper tetrapyrrole
subclass of: metallophthalocyanine

copper tetrapyrrole
type: Class
subclass of: metallotetrapyrrole
subclass of: copper coordination entity

sarcosine
type: Class
subclass of: N-methyl-amino acid
subclass of: N-methylglycines

aldose
type: Class
subclass of: monosaccharide
definition: Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.
charge: 0
formula: C2H4O2(CH2O)n
has_alternative_id: CHEBI:13755
has_alternative_id: CHEBI:22305
has_alternative_id: CHEBI:2561
database_cross_reference: KEGG:C01370
database_cross_reference: Wikipedia:Aldose
has_exact_synonym: Aldose
has_obo_namespace: chebi_ontology
has_related_synonym: aldoses
has_related_synonym: an aldose
id: CHEBI:15693
in_subset: 3 STAR

Axiom
annotated source: aldose
annotated property: has_exact_synonym
annotated target: Aldose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: aldose
annotated property: has_related_synonym
annotated target: aldoses
database_cross_reference: ChEBI

Axiom
annotated source: aldose
annotated property: has_related_synonym
annotated target: an aldose
database_cross_reference: UniProt

primary alcohol
type: Class
subclass of: alcohol

polypeptide
type: Class
subclass of: peptide
subclass of: macromolecule
definition: A peptide containing ten or more amino acid residues.
formula: C4H6N2O3R2(C2H2NOR)n
has_alternative_id: CHEBI:14860
has_alternative_id: CHEBI:8314
database_cross_reference: KEGG:C00403
has_exact_synonym: Polypeptide
has_exact_synonym: polypeptides
has_obo_namespace: chebi_ontology
has_related_synonym: Polypeptid
has_related_synonym: polipeptido
id: CHEBI:15841
in_subset: 3 STAR

Axiom
annotated source: polypeptide
annotated property: has_exact_synonym
annotated target: Polypeptide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polypeptide
annotated property: has_exact_synonym
annotated target: polypeptides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: polypeptide
annotated property: has_related_synonym
annotated target: Polypeptid
database_cross_reference: ChEBI

Axiom
annotated source: polypeptide
annotated property: has_related_synonym
annotated target: polipeptido
database_cross_reference: ChEBI

polynucleotide
type: Class
subclass of: information biomacromolecule
subclass of: nucleobase-containing molecular entity
subclass of: Restriction
  on property: has part
  some values from: nucleotide residue
definition: A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues.
charge: 0
formula: (C5H8O6PR)n.C10H17O10PR2
has_alternative_id: CHEBI:13672
has_alternative_id: CHEBI:14859
has_alternative_id: CHEBI:8312
database_cross_reference: KEGG:C00419
has_exact_synonym: Polynucleotide
has_obo_namespace: chebi_ontology
has_related_synonym: polynucleotides
id: CHEBI:15986
in_subset: 3 STAR

Axiom
annotated source: polynucleotide
annotated property: has_exact_synonym
annotated target: Polynucleotide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polynucleotide
annotated property: has_related_synonym
annotated target: polynucleotides
database_cross_reference: ChEBI

GTP
type: Class
subclass of: purine ribonucleoside 5'-triphosphate
subclass of: guanosine 5'-phosphate

halide anion
type: Class
subclass of: monoatomic monoanion
subclass of: monovalent inorganic anion

ammonia
type: Class
subclass of: independent continuant
subclass of: gas molecular entity
subclass of: azane
subclass of: mononuclear parent hydride
definition: An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
charge: 0
formula: H3N
inchi: InChI=1S/H3N/h1H3
inchikey: QGZKDVFQNNGYKY-UHFFFAOYSA-N
mass: 17.03056
monoisotopicmass: 17.02655
smiles: [H]N([H])[H]
has_alternative_id: CHEBI:13405
has_alternative_id: CHEBI:13406
has_alternative_id: CHEBI:13407
has_alternative_id: CHEBI:13771
has_alternative_id: CHEBI:22533
has_alternative_id: CHEBI:44269
has_alternative_id: CHEBI:44284
has_alternative_id: CHEBI:44404
has_alternative_id: CHEBI:7434
database_cross_reference: Beilstein:3587154
database_cross_reference: CAS:7664-41-7
database_cross_reference: Drug_Central:4625
database_cross_reference: Gmelin:79
database_cross_reference: HMDB:HMDB0000051
database_cross_reference: KEGG:C00014
database_cross_reference: KEGG:D02916
database_cross_reference: KNApSAcK:C00007267
database_cross_reference: MetaCyc:AMMONIA
database_cross_reference: MolBase:930
database_cross_reference: PDBeChem:NH3
database_cross_reference: PMID:110589
database_cross_reference: PMID:11139349
database_cross_reference: PMID:11540049
database_cross_reference: PMID:11746427
database_cross_reference: PMID:11783653
database_cross_reference: PMID:13753780
database_cross_reference: PMID:14663195
database_cross_reference: PMID:15092448
database_cross_reference: PMID:15094021
database_cross_reference: PMID:15554424
database_cross_reference: PMID:15969015
database_cross_reference: PMID:16008360
database_cross_reference: PMID:16050680
database_cross_reference: PMID:16348008
database_cross_reference: PMID:16349403
database_cross_reference: PMID:16614889
database_cross_reference: PMID:16664306
database_cross_reference: PMID:16842901
database_cross_reference: PMID:17025297
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17569513
database_cross_reference: PMID:17737668
database_cross_reference: PMID:18670398
database_cross_reference: PMID:22002069
database_cross_reference: PMID:22081570
database_cross_reference: PMID:22088435
database_cross_reference: PMID:22100291
database_cross_reference: PMID:22130175
database_cross_reference: PMID:22150211
database_cross_reference: PMID:22240068
database_cross_reference: PMID:22290316
database_cross_reference: PMID:22342082
database_cross_reference: PMID:22385337
database_cross_reference: PMID:22443779
database_cross_reference: PMID:22560242
database_cross_reference: Reaxys:3587154
database_cross_reference: Wikipedia:Ammonia
has_exact_synonym: AMMONIA
has_exact_synonym: Ammonia
has_exact_synonym: ammonia
has_exact_synonym: azane
has_obo_namespace: chebi_ontology
has_related_synonym: Ammoniak
has_related_synonym: NH3
has_related_synonym: R-717
has_related_synonym: [NH3]
has_related_synonym: ammoniac

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: Beilstein:3587154
source: Beilstein

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: CAS:7664-41-7
source: ChemIDplus

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: CAS:7664-41-7
source: KEGG COMPOUND

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: CAS:7664-41-7
source: NIST Chemistry WebBook

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: Drug_Central:4625
source: DrugCentral

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: Gmelin:79
source: Gmelin

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:110589
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11139349
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11540049
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11746427
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:11783653
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:13753780
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:14663195
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15092448
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15094021
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15554424
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:15969015
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16008360
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16050680
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16348008
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16349403
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16614889
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16664306
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:16842901
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17025297
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17439666
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17569513
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:17737668
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:18670398
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22002069
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22081570
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22088435
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22100291
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22130175
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22150211
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22240068
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22290316
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22342082
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22385337
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22443779
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: PMID:22560242
source: Europe PMC

Axiom
annotated source: ammonia
annotated property: database_cross_reference
annotated target: Reaxys:3587154
source: Reaxys

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: AMMONIA
database_cross_reference: PDBeChem

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: Ammonia
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: ammonia
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: ammonia
annotated property: has_exact_synonym
annotated target: azane
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: Ammoniak
database_cross_reference: ChemIDplus

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: NH3
database_cross_reference: IUPAC

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: NH3
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: NH3
database_cross_reference: UniProt

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: R-717
database_cross_reference: ChEBI

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: [NH3]
database_cross_reference: MolBase

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: ammoniac
database_cross_reference: ChEBI

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: amoniaco
database_cross_reference: ChEBI

Axiom
annotated source: ammonia
annotated property: has_related_synonym
annotated target: spirit of hartshorn
database_cross_reference: ChemIDplus

hydrogen sulfide
type: Class
subclass of: gas molecular entity
subclass of: hydracid
subclass of: sulfur hydride
subclass of: mononuclear parent hydride

methane
type: Class
subclass of: gas molecular entity
subclass of: alkane
subclass of: mononuclear parent hydride
subclass of: one-carbon compound

sulfate
type: Class
subclass of: independent continuant
subclass of: sulfur oxoanion
subclass of: sulfur oxide
subclass of: divalent inorganic anion
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogensulfate
definition: A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid.
charge: -2
formula: O4S
inchi: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
inchikey: QAOWNCQODCNURD-UHFFFAOYSA-L
mass: 96.06360
monoisotopicmass: 95.95283
smiles: [O-]S([O-])(=O)=O
has_alternative_id: CHEBI:15135
has_alternative_id: CHEBI:45687
has_alternative_id: CHEBI:9335
database_cross_reference: Beilstein:3648446
database_cross_reference: CAS:14808-79-8
database_cross_reference: Gmelin:2120
database_cross_reference: HMDB:HMDB0001448
database_cross_reference: KEGG:C00059
database_cross_reference: KEGG:D05963
database_cross_reference: MetaCyc:SULFATE
database_cross_reference: PDBeChem:SO4
database_cross_reference: PMID:11200094
database_cross_reference: PMID:11452993
database_cross_reference: PMID:11581495
database_cross_reference: PMID:11798107
database_cross_reference: PMID:12166931
database_cross_reference: PMID:12668033
database_cross_reference: PMID:14597181
database_cross_reference: PMID:15093386
database_cross_reference: PMID:15984785
database_cross_reference: PMID:16186560
database_cross_reference: PMID:16345535
database_cross_reference: PMID:16347366
database_cross_reference: PMID:16348007
database_cross_reference: PMID:16483812
database_cross_reference: PMID:16534979
database_cross_reference: PMID:16656509
database_cross_reference: PMID:16742508
database_cross_reference: PMID:16742518
database_cross_reference: PMID:17120760
database_cross_reference: PMID:17420092
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17709180
database_cross_reference: PMID:18398178
database_cross_reference: PMID:18815700
database_cross_reference: PMID:18846414
database_cross_reference: PMID:19047345
database_cross_reference: PMID:19244483
database_cross_reference: PMID:19544990
database_cross_reference: PMID:19628332
database_cross_reference: PMID:19812358
database_cross_reference: PMID:30398859
database_cross_reference: Reaxys:3648446
database_cross_reference: Wikipedia:Sulfate
has_exact_synonym: Sulfate
has_exact_synonym: sulfate
has_exact_synonym: tetraoxidosulfate(2-)
has_exact_synonym: tetraoxosulfate(2-)
has_exact_synonym: tetraoxosulfate(VI)
has_obo_namespace: chebi_ontology
has_related_synonym: SO4(2-)
has_related_synonym: SULFATE ION
has_related_synonym: Sulfate anion(2-)
has_related_synonym: Sulfate dianion
has_related_synonym: Sulfate(2-)
has_related_synonym: Sulfuric acid ion(2-)
has_related_synonym: [SO4](2-)
has_related_synonym: sulphate
has_related_synonym: sulphate ion
id: CHEBI:16189
in_subset: 3 STAR

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: Beilstein:3648446
source: Beilstein

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: CAS:14808-79-8
source: ChemIDplus

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: CAS:14808-79-8
source: NIST Chemistry WebBook

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: Gmelin:2120
source: Gmelin

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11200094
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11452993
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11581495
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:11798107
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:12166931
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:12668033
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:14597181
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:15093386
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:15984785
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16186560
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16345535
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16347366
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16348007
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16483812
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16534979
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16656509
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16742508
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:16742518
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17120760
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17420092
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17439666
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:17709180
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:18398178
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:18815700
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:18846414
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19047345
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19244483
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19544990
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19628332
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:19812358
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: PMID:30398859
source: Europe PMC

Axiom
annotated source: sulfate
annotated property: database_cross_reference
annotated target: Reaxys:3648446
source: Reaxys

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: Sulfate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: sulfate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: sulfate
database_cross_reference: UniProt

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: tetraoxidosulfate(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: tetraoxosulfate(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: has_exact_synonym
annotated target: tetraoxosulfate(VI)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: SO4(2-)
database_cross_reference: IUPAC

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: SULFATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: Sulfate anion(2-)
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: Sulfate dianion
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: Sulfate(2-)
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: Sulfuric acid ion(2-)
database_cross_reference: HMDB

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: [SO4](2-)
database_cross_reference: IUPAC

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: sulphate
database_cross_reference: ChEBI

Axiom
annotated source: sulfate
annotated property: has_related_synonym
annotated target: sulphate ion
database_cross_reference: ChEBI

urea
type: Class
subclass of: monocarboxylic acid amide
subclass of: one-carbon compound

hydroxide
type: Class
subclass of: oxygen hydride

ethanol
type: Class
subclass of: volatile organic compound
subclass of: ethanols
subclass of: alkyl alcohol

hydrogen peroxide
type: Class
subclass of: inorganic peroxide
subclass of: reactive oxygen species

chitosan
type: Class
subclass of: aminoglycan
subclass of: exopolysaccharide

nitrite
type: Class
subclass of: nitrogen oxoanion
subclass of: reactive nitrogen species
subclass of: monovalent inorganic anion

hyaluronic acid
type: Class
subclass of: independent continuant
subclass of: mucopolysaccharide
subclass of: exopolysaccharide
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hyaluronate
definition: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells.
charge: 0
formula: (C14H21NO12)n
has_alternative_id: CHEBI:14412
has_alternative_id: CHEBI:24622
has_alternative_id: CHEBI:24623
has_alternative_id: CHEBI:5772
database_cross_reference: Beilstein:8538277
database_cross_reference: CAS:9004-61-9
database_cross_reference: HMDB:HMDB0010366
database_cross_reference: KEGG:C00518
database_cross_reference: KEGG:D08043
database_cross_reference: KEGG:G10505
database_cross_reference: PMID:11122186
database_cross_reference: PMID:18056362
database_cross_reference: PMID:18290544
database_cross_reference: Reaxys:8187837
database_cross_reference: Wikipedia:Hyaluronan
has_exact_synonym: Hyaluronic acid
has_obo_namespace: chebi_ontology
has_related_synonym: Hyaluronsaeure
has_related_synonym: [beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n
has_related_synonym: [beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n
has_related_synonym: acide hyaluronique
has_related_synonym: acido hialuronico
has_related_synonym: hyaluronan
id: CHEBI:16336
in_subset: 3 STAR

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: Beilstein:8538277
source: Beilstein

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: CAS:9004-61-9
source: ChemIDplus

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: CAS:9004-61-9
source: KEGG COMPOUND

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: PMID:11122186
source: Europe PMC

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: PMID:18056362
source: Europe PMC

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: PMID:18290544
source: Europe PMC

Axiom
annotated source: hyaluronic acid
annotated property: database_cross_reference
annotated target: Reaxys:8187837
source: Reaxys

Axiom
annotated source: hyaluronic acid
annotated property: has_exact_synonym
annotated target: Hyaluronic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hyaluronic acid
annotated property: has_related_synonym
annotated target: Hyaluronsaeure
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: has_related_synonym
annotated target: [beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: has_related_synonym
annotated target: [beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hyaluronic acid
annotated property: has_related_synonym
annotated target: acide hyaluronique
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: has_related_synonym
annotated target: acido hialuronico
database_cross_reference: ChEBI

Axiom
annotated source: hyaluronic acid
annotated property: has_related_synonym
annotated target: hyaluronan
database_cross_reference: ChEBI

pantothenate
type: Class
subclass of: monocarboxylic acid anion

NADPH
type: Class
subclass of: NAD(P)H
subclass of: NADP

naphthalene
type: Class
subclass of: naphthalenes
subclass of: ortho-fused bicyclic arene

carbon dioxide
type: Class
subclass of: gas molecular entity
subclass of: carbon oxide
subclass of: one-carbon compound

protein polypeptide chain
type: Class
subclass of: polypeptide
subclass of: Restriction
  on property: has part
  some values from: proteinogenic amino-acid residue
definition: A naturally occurring polypeptide synthesized at the ribosome.
has_alternative_id: CHEBI:8526
database_cross_reference: KEGG:C00017
has_obo_namespace: chebi_ontology
has_related_synonym: Protein
has_related_synonym: a protein
has_related_synonym: polypeptide chain
has_related_synonym: protein polypeptide chains
id: CHEBI:16541
in_subset: 3 STAR

Axiom
annotated source: protein polypeptide chain
annotated property: has_related_synonym
annotated target: Protein
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: protein polypeptide chain
annotated property: has_related_synonym
annotated target: a protein
database_cross_reference: UniProt

Axiom
annotated source: protein polypeptide chain
annotated property: has_related_synonym
annotated target: polypeptide chain
database_cross_reference: ChEBI

Axiom
annotated source: protein polypeptide chain
annotated property: has_related_synonym
annotated target: protein polypeptide chains
database_cross_reference: ChEBI

carbohydrate
type: Class
subclass of: carbohydrates and carbohydrate derivatives
definition: Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.
has_alternative_id: CHEBI:15131
has_alternative_id: CHEBI:23008
has_alternative_id: CHEBI:9318
database_cross_reference: Wikipedia:Carbohydrate
has_exact_synonym: carbohydrate
has_exact_synonym: carbohydrates
has_obo_namespace: chebi_ontology
has_related_synonym: Kohlenhydrat
has_related_synonym: Kohlenhydrate
has_related_synonym: a carbohydrate
has_related_synonym: carbohidrato
has_related_synonym: carbohidratos
has_related_synonym: glucide
has_related_synonym: glucides
has_related_synonym: glucido
has_related_synonym: glucidos
has_related_synonym: hydrates de carbone
has_related_synonym: saccharide
has_related_synonym: saccharides
has_related_synonym: saccharidum
id: CHEBI:16646
in_subset: 3 STAR

Axiom
annotated source: carbohydrate
annotated property: has_exact_synonym
annotated target: carbohydrate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbohydrate
annotated property: has_exact_synonym
annotated target: carbohydrates
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: Kohlenhydrat
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: Kohlenhydrate
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: a carbohydrate
database_cross_reference: UniProt

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: carbohidrato
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: carbohidratos
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: glucide
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: glucides
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: glucido
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: glucidos
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: hydrates de carbone
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: saccharide
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: saccharides
database_cross_reference: IUPAC

Axiom
annotated source: carbohydrate
annotated property: has_related_synonym
annotated target: saccharidum
database_cross_reference: ChEBI

peptide
type: Class
subclass of: carboxamide
subclass of: organic amino compound
subclass of: Restriction
  on property: has part
  some values from: amino-acid residue
subclass of: Restriction
  on property: is tautomer of
  some values from: peptide zwitterion
definition: Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
charge: 0
formula: (C2H2NOR)nC2H3NOR
has_alternative_id: CHEBI:14753
has_alternative_id: CHEBI:25906
has_alternative_id: CHEBI:7990
database_cross_reference: KEGG:C00012
has_exact_synonym: Peptide
has_exact_synonym: peptides
has_obo_namespace: chebi_ontology
has_related_synonym: Peptid
has_related_synonym: peptido
has_related_synonym: peptidos
id: CHEBI:16670
in_subset: 3 STAR

Axiom
annotated source: peptide
annotated property: has_exact_synonym
annotated target: Peptide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: peptide
annotated property: has_exact_synonym
annotated target: peptides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: peptide
annotated property: has_related_synonym
annotated target: Peptid
database_cross_reference: ChEBI

Axiom
annotated source: peptide
annotated property: has_related_synonym
annotated target: peptido
database_cross_reference: ChEBI

Axiom
annotated source: peptide
annotated property: has_related_synonym
annotated target: peptidos
database_cross_reference: ChEBI

noradrenaline(1+)
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: noradrenaline
charge: +1
formula: C8H12NO3
inchi: InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1
inchikey: SFLSHLFXELFNJZ-UHFFFAOYSA-O
mass: 170.187
monoisotopicmass: 170.08117
smiles: C1=CC(=CC(=C1O)O)C(C[NH3+])O
has_obo_namespace: chebi_ontology
has_related_synonym: noradrenaline
id: CHEBI:166902
in_subset: 2 STAR

Axiom
annotated source: noradrenaline(1+)
annotated property: has_related_synonym
annotated target: noradrenaline
database_cross_reference: UniProt

soybean oil
type: Class
subclass of: mixture

nucleoside 5'-phosphate
type: Class
subclass of: mononucleotide

benzene
type: Class
subclass of: volatile organic compound
subclass of: benzenes
subclass of: aromatic annulene

mineral nutrient
type: Class
subclass of: mineral

glycan
type: Class
subclass of: carbohydrates and carbohydrate derivatives
definition: Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001.
has_obo_namespace: chebi_ontology
has_related_synonym: glycans
id: CHEBI:167559
in_subset: 3 STAR

Axiom
annotated source: glycan
annotated property: has_related_synonym
annotated target: glycans
database_cross_reference: ChEBI

paralytic shellfish toxin
type: Class
subclass of: pyrrolopurine
subclass of: alkaloid
subclass of: guanidines
subclass of: ketone hydrate

tryptamine
type: Class
subclass of: tryptamines
subclass of: aminoalkylindole
subclass of: indole alkaloid
subclass of: aralkylamino compound
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: tryptaminium
definition: An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.
charge: 0
formula: C10H12N2
inchi: InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2
inchikey: APJYDQYYACXCRM-UHFFFAOYSA-N
mass: 160.21570
monoisotopicmass: 160.10005
smiles: NCCc1c[nH]c2ccccc12
has_alternative_id: CHEBI:15274
has_alternative_id: CHEBI:27161
has_alternative_id: CHEBI:46157
has_alternative_id: CHEBI:9767
database_cross_reference: Beilstein:125513
database_cross_reference: CAS:61-54-1
database_cross_reference: DrugBank:DB08653
database_cross_reference: Gmelin:603448
database_cross_reference: HMDB:HMDB0000303
database_cross_reference: KEGG:C00398
database_cross_reference: KNApSAcK:C00001434
database_cross_reference: MetaCyc:TRYPTAMINE
database_cross_reference: PDBeChem:TSS
database_cross_reference: PMID:16126914
database_cross_reference: PMID:22770225
database_cross_reference: PMID:24345948
database_cross_reference: PMID:24558969
database_cross_reference: Reaxys:125513
database_cross_reference: Wikipedia:Tryptamine
has_exact_synonym: 2-(1H-indol-3-yl)ethanamine
has_exact_synonym: Tryptamine
has_obo_namespace: chebi_ontology
has_related_synonym: 1H-indole-3-ethanamine
has_related_synonym: 2-(1H-INDOL-3-YL)ETHANAMINE
has_related_synonym: 2-(3-indolyl)ethylamine
has_related_synonym: 3-(2-Aminoethyl)indole
id: CHEBI:16765
in_subset: 3 STAR

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: CAS:61-54-1
source: ChemIDplus

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: CAS:61-54-1
source: KEGG COMPOUND

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: CAS:61-54-1
source: NIST Chemistry WebBook

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: Gmelin:603448
source: Gmelin

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:16126914
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:22770225
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:24345948
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: PMID:24558969
source: Europe PMC

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: Reaxys:125513
source: Reaxys

Axiom
annotated source: tryptamine
annotated property: has_exact_synonym
annotated target: 2-(1H-indol-3-yl)ethanamine
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: tryptamine
annotated property: has_exact_synonym
annotated target: Tryptamine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: tryptamine
annotated property: has_related_synonym
annotated target: 1H-indole-3-ethanamine
database_cross_reference: NIST_Chemistry_WebBook

Axiom
annotated source: tryptamine
annotated property: has_related_synonym
annotated target: 2-(1H-INDOL-3-YL)ETHANAMINE
database_cross_reference: PDBeChem

Axiom
annotated source: tryptamine
annotated property: has_related_synonym
annotated target: 2-(3-indolyl)ethylamine
database_cross_reference: ChemIDplus

Axiom
annotated source: tryptamine
annotated property: has_related_synonym
annotated target: 3-(2-Aminoethyl)indole
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: tryptamine
annotated property: database_cross_reference
annotated target: Beilstein:125513
source: Beilstein

formaldehyde
type: Class
subclass of: aldehyde
subclass of: one-carbon compound

chlorophyllide a
type: Class
subclass of: methyl ester
subclass of: dicarboxylic acid monoester
subclass of: chlorophyllide

NADH
type: Class
subclass of: NAD
subclass of: NAD(P)H

heteroglycan
type: Class
subclass of: polysaccharide

bilirubin IXalpha
type: Class
subclass of: dicarboxylic acid
subclass of: biladienes
subclass of: Restriction
  on property: has part
  some values from: 24G7 epitope
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: bilirubin(2-)
definition: A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.
charge: 0
formula: C33H36N4O6
inchi: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-
inchikey: BPYKTIZUTYGOLE-IFADSCNNSA-N
mass: 584.673
monoisotopicmass: 584.26348
has_alternative_id: CHEBI:13898
has_alternative_id: CHEBI:22870
has_alternative_id: CHEBI:3099
database_cross_reference: Beilstein:74376
database_cross_reference: CAS:635-65-4
database_cross_reference: Gmelin:411033
database_cross_reference: HMDB:HMDB0000054
database_cross_reference: KEGG:C00486
database_cross_reference: KNApSAcK:C00029828
database_cross_reference: MetaCyc:BILIRUBIN
database_cross_reference: PDBeChem:BLR
database_cross_reference: PMID:12799017
database_cross_reference: PMID:18442622
database_cross_reference: PMID:23763371
database_cross_reference: PMID:23768684
database_cross_reference: PMID:30224965
database_cross_reference: PMID:8605219
database_cross_reference: PMID:9587403
database_cross_reference: Reaxys:74376
database_cross_reference: Wikipedia:Bilirubin
has_exact_synonym: 3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
has_exact_synonym: bilirubin
has_obo_namespace: chebi_ontology
has_related_synonym: 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid
has_related_synonym: 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
has_related_synonym: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
has_related_synonym: 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione
has_related_synonym: Bilirubin
has_related_synonym: bilirubin(Z,Z)
has_related_synonym: bilirubin-IXalpha
id: CHEBI:16990
in_subset: 3 STAR

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: Beilstein:74376
source: Beilstein

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: CAS:635-65-4
source: ChemIDplus

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: CAS:635-65-4
source: KEGG COMPOUND

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: Gmelin:411033
source: Gmelin

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:12799017
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:18442622
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:23763371
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:23768684
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:30224965
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:8605219
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: PMID:9587403
source: Europe PMC

Axiom
annotated source: bilirubin IXalpha
annotated property: database_cross_reference
annotated target: Reaxys:74376
source: Reaxys

Axiom
annotated source: bilirubin IXalpha
annotated property: has_exact_synonym
annotated target: 3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: bilirubin IXalpha
annotated property: has_exact_synonym
annotated target: bilirubin
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: bilirubin IXalpha
annotated property: has_related_synonym
annotated target: 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: bilirubin IXalpha
annotated property: has_related_synonym
annotated target: 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: bilirubin IXalpha
annotated property: has_related_synonym
annotated target: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid
database_cross_reference: IUPAC

Axiom
annotated source: bilirubin IXalpha
annotated property: has_related_synonym
annotated target: 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione
database_cross_reference: JCBN

Axiom
annotated source: bilirubin IXalpha
annotated property: has_related_synonym
annotated target: Bilirubin
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bilirubin IXalpha
annotated property: has_related_synonym
annotated target: bilirubin(Z,Z)
database_cross_reference: ChEBI

Axiom
annotated source: bilirubin IXalpha
annotated property: has_related_synonym
annotated target: bilirubin-IXalpha
database_cross_reference: ChEBI

deoxyribonucleic acid
type: Class
subclass of: independent continuant
subclass of: nucleic acid
subclass of: Restriction
  on property: has part
  some values from: canonical deoxyribonucleoside residue
subclass of: Restriction
  on property: has part
  some values from: canonical deoxyribonucleotide residue
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
definition: High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.
has_alternative_id: CHEBI:13302
has_alternative_id: CHEBI:21123
has_alternative_id: CHEBI:33698
has_alternative_id: CHEBI:4291
database_cross_reference: CAS:9007-49-2
database_cross_reference: KEGG:C00039
has_exact_synonym: Deoxyribonucleic acid
has_exact_synonym: deoxyribonucleic acids
has_obo_namespace: chebi_ontology
has_related_synonym: (Deoxyribonucleotide)m
has_related_synonym: (Deoxyribonucleotide)n
has_related_synonym: (Deoxyribonucleotide)n+m
has_related_synonym: DNA
has_related_synonym: DNAn
has_related_synonym: DNAn+1
has_related_synonym: DNS
has_related_synonym: Desoxyribonukleinsaeure
has_related_synonym: deoxyribonucleic acids
has_related_synonym: desoxyribose nucleic acid
has_related_synonym: thymus nucleic acid
id: CHEBI:16991
in_subset: 3 STAR

Axiom
annotated source: deoxyribonucleic acid
annotated property: database_cross_reference
annotated target: CAS:9007-49-2
source: ChemIDplus

Axiom
annotated source: deoxyribonucleic acid
annotated property: database_cross_reference
annotated target: CAS:9007-49-2
source: KEGG COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_exact_synonym
annotated target: Deoxyribonucleic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_exact_synonym
annotated target: deoxyribonucleic acids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: (Deoxyribonucleotide)m
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: (Deoxyribonucleotide)n
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: (Deoxyribonucleotide)n+m
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: DNA
database_cross_reference: IUPAC

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: DNA
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: DNA
database_cross_reference: UniProt

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: DNAn
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: DNAn+1
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: DNS
database_cross_reference: ChEBI

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: Desoxyribonukleinsaeure
database_cross_reference: ChEBI

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: deoxyribonucleic acids
database_cross_reference: ChEBI

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: desoxyribose nucleic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: deoxyribonucleic acid
annotated property: has_related_synonym
annotated target: thymus nucleic acid
database_cross_reference: ChEBI

propane-1,2-diol
type: Class
subclass of: propane-1,2-diols

chitin
type: Class
subclass of: N-acylglucosamine
subclass of: aminoglycan

dinitrogen oxide
type: Class
subclass of: gas molecular entity
subclass of: nitrogen oxide

fluoride
type: Class
subclass of: halide anion
subclass of: monoatomic fluorine

ketone
type: Class
subclass of: carbonyl compound
definition: A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).
charge: 0
formula: COR2
mass: 28.010
monoisotopicmass: 27.99491
smiles: [*]C([*])=O
has_alternative_id: CHEBI:13427
has_alternative_id: CHEBI:13646
has_alternative_id: CHEBI:24974
has_alternative_id: CHEBI:6127
has_alternative_id: CHEBI:8742
database_cross_reference: KEGG:C01450
database_cross_reference: Wikipedia:Ketone
has_exact_synonym: Ketone
has_exact_synonym: ketones
has_obo_namespace: chebi_ontology
has_related_synonym: Keton
has_related_synonym: R-CO-R'
has_related_synonym: a ketone
has_related_synonym: cetone
has_related_synonym: ketones
id: CHEBI:17087
in_subset: 3 STAR

Axiom
annotated source: ketone
annotated property: has_exact_synonym
annotated target: Ketone
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ketone
annotated property: has_exact_synonym
annotated target: ketones
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: ketone
annotated property: has_related_synonym
annotated target: Keton
database_cross_reference: ChEBI

Axiom
annotated source: ketone
annotated property: has_related_synonym
annotated target: R-CO-R'
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ketone
annotated property: has_related_synonym
annotated target: a ketone
database_cross_reference: UniProt

Axiom
annotated source: ketone
annotated property: has_related_synonym
annotated target: cetone
database_cross_reference: ChEBI

Axiom
annotated source: ketone
annotated property: has_related_synonym
annotated target: ketones
database_cross_reference: ChEBI

glycoprotein
type: Class
subclass of: conjugated protein
subclass of: carbohydrate derivative
definition: A compound in which a carbohydrate component is covalently bound to a protein component.
has_alternative_id: CHEBI:14349
has_alternative_id: CHEBI:5481
has_alternative_id: CHEBI:5493
database_cross_reference: KEGG:C00326
has_exact_synonym: Glycoprotein
has_exact_synonym: glycoproteins
has_obo_namespace: chebi_ontology
has_related_synonym: Glykoprotein
has_related_synonym: Glykoproteine
has_related_synonym: a glycoprotein
has_related_synonym: glicoproteina
has_related_synonym: glicoproteinas
has_related_synonym: glycoproteine
has_related_synonym: glycoproteines
id: CHEBI:17089
in_subset: 3 STAR

Axiom
annotated source: glycoprotein
annotated property: has_exact_synonym
annotated target: Glycoprotein
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glycoprotein
annotated property: has_exact_synonym
annotated target: glycoproteins
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: glycoprotein
annotated property: has_related_synonym
annotated target: Glykoprotein
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: has_related_synonym
annotated target: Glykoproteine
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: has_related_synonym
annotated target: a glycoprotein
database_cross_reference: UniProt

Axiom
annotated source: glycoprotein
annotated property: has_related_synonym
annotated target: glicoproteina
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: has_related_synonym
annotated target: glicoproteinas
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: has_related_synonym
annotated target: glycoproteine
database_cross_reference: ChEBI

Axiom
annotated source: glycoprotein
annotated property: has_related_synonym
annotated target: glycoproteines
database_cross_reference: ChEBI

glucose
type: Class
subclass of: independent continuant
subclass of: aldohexose
subclass of: Restriction
  on property: has role
  some values from: fundamental metabolite
definition: An aldohexose used as a source of energy and metabolic intermediate.
charge: 0
formula: C6H12O6
mass: 180.15588
monoisotopicmass: 180.06339
has_alternative_id: CHEBI:14313
has_alternative_id: CHEBI:24277
has_alternative_id: CHEBI:33929
has_alternative_id: CHEBI:5418
database_cross_reference: CAS:50-99-7
database_cross_reference: KEGG:C00293
database_cross_reference: Wikipedia:Glucose
has_exact_synonym: Glucose
has_exact_synonym: gluco-hexose
has_exact_synonym: glucose
has_obo_namespace: chebi_ontology
has_related_synonym: DL-glucose
has_related_synonym: Glc
has_related_synonym: Glukose
id: CHEBI:17234
in_subset: 3 STAR

Axiom
annotated source: glucose
annotated property: database_cross_reference
annotated target: CAS:50-99-7
source: KEGG COMPOUND

Axiom
annotated source: glucose
annotated property: has_exact_synonym
annotated target: Glucose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glucose
annotated property: has_exact_synonym
annotated target: gluco-hexose
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: glucose
annotated property: has_exact_synonym
annotated target: glucose
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: glucose
annotated property: has_related_synonym
annotated target: DL-glucose
database_cross_reference: ChEBI

Axiom
annotated source: glucose
annotated property: has_related_synonym
annotated target: Glc
database_cross_reference: JCBN

Axiom
annotated source: glucose
annotated property: has_related_synonym
annotated target: Glukose
database_cross_reference: ChEBI

carbon monoxide
type: Class
subclass of: gas molecular entity
subclass of: carbon oxide
subclass of: one-carbon compound

nucleoside 5'-triphoshate
type: Class
subclass of: nucleoside phosphate

testosterone
type: Class
subclass of: C19-steroid
subclass of: 17beta-hydroxy steroid
subclass of: 3-oxo-Delta(4) steroid
subclass of: androstanoid

aldehyde
type: Class
subclass of: carbonyl compound

hydrogencarbonate
type: Class
subclass of: independent continuant
subclass of: carbon oxoanion
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbonate
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbonic acid
definition: The carbon oxoanion resulting from the removal of a proton from carbonic acid.
charge: -1
formula: CHO3
inchi: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
inchikey: BVKZGUZCCUSVTD-UHFFFAOYSA-M
mass: 61.01684
monoisotopicmass: 60.99312
smiles: OC([O-])=O
has_alternative_id: CHEBI:13363
has_alternative_id: CHEBI:22863
has_alternative_id: CHEBI:40961
has_alternative_id: CHEBI:5589
database_cross_reference: Beilstein:3903504
database_cross_reference: CAS:71-52-3
database_cross_reference: Gmelin:49249
database_cross_reference: HMDB:HMDB0000595
database_cross_reference: KEGG:C00288
database_cross_reference: MetaCyc:HCO3
database_cross_reference: PDBeChem:BCT
database_cross_reference: PMID:17215880
database_cross_reference: PMID:17505962
database_cross_reference: PMID:18439416
database_cross_reference: PMID:28732801
database_cross_reference: PMID:29150416
database_cross_reference: PMID:29460248
database_cross_reference: PMID:29466234
database_cross_reference: PMID:4208463
database_cross_reference: Wikipedia:Bicarbonate
has_exact_synonym: Hydrogencarbonate
has_exact_synonym: hydrogen(trioxidocarbonate)(1-)
has_exact_synonym: hydrogencarbonate
has_exact_synonym: hydrogencarbonate(1-)
has_exact_synonym: hydrogentrioxocarbonate(1-)
has_exact_synonym: hydrogentrioxocarbonate(IV)
has_exact_synonym: hydroxidodioxidocarbonate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: Acid carbonate
has_related_synonym: BICARBONATE ION
has_related_synonym: Bicarbonate
has_related_synonym: HCO3(-)
has_related_synonym: HCO3-
has_related_synonym: [CO2(OH)](-)
has_related_synonym: hydrogen carbonate
id: CHEBI:17544
in_subset: 3 STAR

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: Beilstein:3903504
source: Beilstein

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: CAS:71-52-3
source: ChemIDplus

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: Gmelin:49249
source: Gmelin

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:17215880
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:17505962
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:18439416
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:28732801
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:29150416
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:29460248
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:29466234
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: database_cross_reference
annotated target: PMID:4208463
source: Europe PMC

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: Hydrogencarbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogen(trioxidocarbonate)(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogencarbonate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogencarbonate
database_cross_reference: UniProt

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogencarbonate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogentrioxocarbonate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydrogentrioxocarbonate(IV)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_exact_synonym
annotated target: hydroxidodioxidocarbonate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogencarbonate
annotated property: has_related_synonym
annotated target: Acid carbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: has_related_synonym
annotated target: BICARBONATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: hydrogencarbonate
annotated property: has_related_synonym
annotated target: Bicarbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: has_related_synonym
annotated target: HCO3(-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogencarbonate
annotated property: has_related_synonym
annotated target: HCO3-
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydrogencarbonate
annotated property: has_related_synonym
annotated target: [CO2(OH)](-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogencarbonate
annotated property: has_related_synonym
annotated target: hydrogen carbonate
database_cross_reference: PDBeChem

alginic acid
type: Class
subclass of: heteroglycan
subclass of: copolymer macromolecule
subclass of: exopolysaccharide

toluene
type: Class
subclass of: volatile organic compound
subclass of: toluenes
subclass of: methylbenzene

beta-carotene
type: Class
subclass of: carotenoid beta-end derivative
subclass of: cyclic carotene

nitrate
type: Class
subclass of: nitrogen oxoanion
subclass of: reactive nitrogen species
subclass of: monovalent inorganic anion

electron acceptor
type: Class
subclass of: acceptor

methanol
type: Class
subclass of: volatile organic compound
subclass of: primary alcohol
subclass of: alkyl alcohol
subclass of: one-carbon compound

organohalogen compound
type: Class
subclass of: heteroorganic entity
subclass of: halide

hydrogen chloride
type: Class
subclass of: gas molecular entity
subclass of: hydrogen halide
subclass of: chlorine molecular entity
subclass of: mononuclear parent hydride

donor
type: Class
subclass of: chemical role
definition: A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
has_alternative_id: CHEBI:14202
has_alternative_id: CHEBI:4697
database_cross_reference: KEGG:C01351
has_exact_synonym: Donor
has_obo_namespace: chebi_ontology
has_related_synonym: Donator
has_related_synonym: donneur
id: CHEBI:17891
in_subset: 3 STAR

Axiom
annotated source: donor
annotated property: has_exact_synonym
annotated target: Donor
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: donor
annotated property: has_related_synonym
annotated target: Donator
database_cross_reference: ChEBI

Axiom
annotated source: donor
annotated property: has_related_synonym
annotated target: donneur
database_cross_reference: ChEBI

ribonucleoside triphosphate
type: Class
subclass of: nucleoside 5'-triphoshate

chloride
type: Class
subclass of: halide anion
subclass of: monoatomic chlorine

dinitrogen
type: Class
subclass of: gas molecular entity
subclass of: elemental molecule
subclass of: diatomic nitrogen

lipid
type: Class
subclass of: organic molecular entity
definition: 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
has_alternative_id: CHEBI:14517
has_alternative_id: CHEBI:25054
has_alternative_id: CHEBI:6486
database_cross_reference: KEGG:C01356
has_exact_synonym: Lipid
has_exact_synonym: lipids
has_obo_namespace: chebi_ontology
id: CHEBI:18059
in_subset: 3 STAR

Axiom
annotated source: lipid
annotated property: has_exact_synonym
annotated target: Lipid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: lipid
annotated property: has_exact_synonym
annotated target: lipids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

glycosaminoglycan
type: Class
subclass of: aminoglycan
definition: Any polysaccharide containing a substantial proportion of aminomonosaccharide residues.
has_alternative_id: CHEBI:14361
has_alternative_id: CHEBI:24398
has_alternative_id: CHEBI:5495
database_cross_reference: KEGG:C02545
database_cross_reference: Wikipedia:Glycosaminoglycan
has_exact_synonym: Glycosaminoglycan
has_exact_synonym: glycosaminoglycan
has_obo_namespace: chebi_ontology
has_related_synonym: Glykosaminoglykan
has_related_synonym: glicosaminoglicano
has_related_synonym: glycosaminoglycane
has_related_synonym: glycosaminoglycans
id: CHEBI:18085
in_subset: 3 STAR

Axiom
annotated source: glycosaminoglycan
annotated property: has_exact_synonym
annotated target: Glycosaminoglycan
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glycosaminoglycan
annotated property: has_exact_synonym
annotated target: glycosaminoglycan
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: glycosaminoglycan
annotated property: has_related_synonym
annotated target: Glykosaminoglykan
database_cross_reference: ChEBI

Axiom
annotated source: glycosaminoglycan
annotated property: has_related_synonym
annotated target: glicosaminoglicano
database_cross_reference: IUPAC

Axiom
annotated source: glycosaminoglycan
annotated property: has_related_synonym
annotated target: glycosaminoglycane
database_cross_reference: IUPAC

Axiom
annotated source: glycosaminoglycan
annotated property: has_related_synonym
annotated target: glycosaminoglycans
database_cross_reference: ChEBI

hexose
type: Class
subclass of: monosaccharide
definition: Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose).
has_alternative_id: CHEBI:14399
has_alternative_id: CHEBI:24590
has_alternative_id: CHEBI:5709
database_cross_reference: GlyGen:G70994MS
database_cross_reference: GlyTouCan:G70994MS
database_cross_reference: KEGG:C00738
has_exact_synonym: Hexose
has_obo_namespace: chebi_ontology
has_related_synonym: WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/
has_related_synonym: hexoses
id: CHEBI:18133
in_subset: 3 STAR

Axiom
annotated source: hexose
annotated property: has_exact_synonym
annotated target: Hexose
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hexose
annotated property: has_related_synonym
annotated target: WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/
database_cross_reference: GlyTouCan

Axiom
annotated source: hexose
annotated property: has_related_synonym
annotated target: hexoses
database_cross_reference: ChEBI

trimethylamine
type: Class
subclass of: methylamines
subclass of: tertiary amine

hydrogen halide
type: Class
subclass of: hydracid

polysaccharide
type: Class
subclass of: carbohydrate
subclass of: glycan
subclass of: biomacromolecule
definition: A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.
has_alternative_id: CHEBI:14864
has_alternative_id: CHEBI:26205
has_alternative_id: CHEBI:8322
database_cross_reference: KEGG:C00420
has_exact_synonym: Polysaccharide
has_exact_synonym: polysaccharides
has_obo_namespace: chebi_ontology
has_related_synonym: Glycan
has_related_synonym: Glycane
has_related_synonym: Glykan
has_related_synonym: Glykane
has_related_synonym: glycans
has_related_synonym: polisacarido
has_related_synonym: polisacaridos
id: CHEBI:18154
in_subset: 3 STAR

Axiom
annotated source: polysaccharide
annotated property: has_exact_synonym
annotated target: Polysaccharide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polysaccharide
annotated property: has_exact_synonym
annotated target: polysaccharides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: polysaccharide
annotated property: has_related_synonym
annotated target: Glycan
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: polysaccharide
annotated property: has_related_synonym
annotated target: Glycane
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: has_related_synonym
annotated target: Glykan
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: has_related_synonym
annotated target: Glykane
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: has_related_synonym
annotated target: glycans
database_cross_reference: IUPAC

Axiom
annotated source: polysaccharide
annotated property: has_related_synonym
annotated target: polisacarido
database_cross_reference: ChEBI

Axiom
annotated source: polysaccharide
annotated property: has_related_synonym
annotated target: polisacaridos
database_cross_reference: IUPAC

chlorophyll a
type: Class
subclass of: methyl ester
subclass of: chlorophyll

(1->4)-beta-D-glucan
type: Class
subclass of: beta-D-glucan

iron atom
type: Class
subclass of: iron group element atom
definition: An iron group element atom that has atomic number 26.
has_exact_synonym: iron
has_related_synonym: 26Fe
has_related_synonym: Eisen
has_related_synonym: Fe
has_related_synonym: Iron
has_related_synonym: fer
has_related_synonym: ferrum
has_related_synonym: hierro
has_related_synonym: iron

dihydrogen
type: Class
subclass of: gas molecular entity
subclass of: elemental molecule
subclass of: elemental hydrogen

nucleobase
type: Class
subclass of: organonitrogen heterocyclic compound
definition: That part of DNA or RNA that may be involved in pairing.
has_alternative_id: CHEBI:13873
has_alternative_id: CHEBI:25598
has_alternative_id: CHEBI:2995
database_cross_reference: KEGG:C00701
database_cross_reference: Wikipedia:Nucleobase
has_obo_namespace: chebi_ontology
has_related_synonym: Base
has_related_synonym: nucleobases
id: CHEBI:18282
in_subset: 3 STAR

Axiom
annotated source: nucleobase
annotated property: has_related_synonym
annotated target: Base
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: nucleobase
annotated property: has_related_synonym
annotated target: nucleobases
database_cross_reference: ChEBI

manganese atom
type: Class
subclass of: manganese group element atom

alkane
type: Class
subclass of: hydrocarbon
subclass of: aliphatic compound

(R)-noradrenaline
type: Class
subclass of: noradrenaline
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: sympathomimetic agent
subclass of: Restriction
  on property: has role
  some values from: alpha-adrenergic agonist
subclass of: Restriction
  on property: has role
  some values from: vasoconstrictor agent
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: (R)-noradrenaline(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: (S)-noradrenaline
definition: The R-enantiomer of noradrenaline.
charge: 0
formula: C8H11NO3
inchi: InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
inchikey: SFLSHLFXELFNJZ-QMMMGPOBSA-N
mass: 169.17780
monoisotopicmass: 169.07389
smiles: NC[C@H](O)c1ccc(O)c(O)c1
has_alternative_id: CHEBI:1
has_alternative_id: CHEBI:14668
has_alternative_id: CHEBI:25592
has_alternative_id: CHEBI:258884
has_alternative_id: CHEBI:43725
database_cross_reference: Beilstein:2804840
database_cross_reference: Beilstein:4231961
database_cross_reference: CAS:51-41-2
database_cross_reference: DrugBank:DB00368
database_cross_reference: Drug_Central:1960
database_cross_reference: HMDB:HMDB0000216
database_cross_reference: KEGG:C00547
database_cross_reference: KEGG:D00076
database_cross_reference: KNApSAcK:C00001424
database_cross_reference: PDBeChem:LNR
database_cross_reference: Reaxys:2804840
database_cross_reference: Wikipedia:Norepinephrine
has_exact_synonym: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-arterenol
has_related_synonym: (-)-noradrenaline
has_related_synonym: (-)-norepinephrine
has_related_synonym: (R)-(-)-norepinephrine
has_related_synonym: (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol
has_related_synonym: (R)-norepinephrine
has_related_synonym: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
has_related_synonym: Arterenol
has_related_synonym: L-NOREPINEPHRINE
has_related_synonym: L-Noradrenaline
has_related_synonym: Noradrenaline
has_related_synonym: Norepinephrine
has_related_synonym: norepinefrina
has_related_synonym: norepinephrine
has_related_synonym: norepinephrinum
id: CHEBI:18357
in_subset: 3 STAR

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: Beilstein:2804840
source: Beilstein

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: Beilstein:4231961
source: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: CAS:51-41-2
source: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: CAS:51-41-2
source: KEGG COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: Drug_Central:1960
source: DrugCentral

Axiom
annotated source: (R)-noradrenaline
annotated property: database_cross_reference
annotated target: Reaxys:2804840
source: Reaxys

Axiom
annotated source: (R)-noradrenaline
annotated property: has_exact_synonym
annotated target: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: (-)-arterenol
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: (-)-noradrenaline
database_cross_reference: IUPHAR

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: (-)-norepinephrine
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: (R)-(-)-norepinephrine
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: (R)-norepinephrine
database_cross_reference: ChemIDplus

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: Arterenol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: L-NOREPINEPHRINE
database_cross_reference: PDBeChem

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: L-Noradrenaline
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: Noradrenaline
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: Norepinephrine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: norepinefrina
database_cross_reference: ChEBI
has_synonym_type: INN

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: norepinephrine
database_cross_reference: ChemIDplus
has_synonym_type: INN

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: norepinephrine
database_cross_reference: WHO_MedNet
has_synonym_type: INN

Axiom
annotated source: (R)-noradrenaline
annotated property: has_related_synonym
annotated target: norepinephrinum
database_cross_reference: ChEBI
has_synonym_type: INN

phosphate(3-)
type: Class
subclass of: phosphate ion
subclass of: trivalent inorganic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogenphosphate
definition: A phosphate ion that is the conjugate base of hydrogenphosphate.
charge: -3
formula: O4P
inchi: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
inchikey: NBIIXXVUZAFLBC-UHFFFAOYSA-K
mass: 94.97136
monoisotopicmass: 94.95507
smiles: [O-]P([O-])([O-])=O
has_alternative_id: CHEBI:14791
has_alternative_id: CHEBI:45024
has_alternative_id: CHEBI:7793
database_cross_reference: Beilstein:3903772
database_cross_reference: CAS:14265-44-2
database_cross_reference: Gmelin:1997
database_cross_reference: KEGG:C00009
database_cross_reference: PDBeChem:PO4
database_cross_reference: Reaxys:3903772
has_exact_synonym: phosphate
has_exact_synonym: tetraoxidophosphate(3-)
has_exact_synonym: tetraoxophosphate(3-)
has_exact_synonym: tetraoxophosphate(V)
has_obo_namespace: chebi_ontology
has_related_synonym: Orthophosphate
has_related_synonym: PHOSPHATE ION
has_related_synonym: PO4(3-)
has_related_synonym: Phosphate
has_related_synonym: [PO4](3-)
id: CHEBI:18367
in_subset: 3 STAR

Axiom
annotated source: phosphate(3-)
annotated property: database_cross_reference
annotated target: Beilstein:3903772
source: Beilstein

Axiom
annotated source: phosphate(3-)
annotated property: database_cross_reference
annotated target: CAS:14265-44-2
source: ChemIDplus

Axiom
annotated source: phosphate(3-)
annotated property: database_cross_reference
annotated target: CAS:14265-44-2
source: KEGG COMPOUND

Axiom
annotated source: phosphate(3-)
annotated property: database_cross_reference
annotated target: Gmelin:1997
source: Gmelin

Axiom
annotated source: phosphate(3-)
annotated property: database_cross_reference
annotated target: PDBeChem:PO4
source: ChEBI

Axiom
annotated source: phosphate(3-)
annotated property: database_cross_reference
annotated target: Reaxys:3903772
source: Reaxys

Axiom
annotated source: phosphate(3-)
annotated property: has_exact_synonym
annotated target: phosphate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphate(3-)
annotated property: has_exact_synonym
annotated target: tetraoxidophosphate(3-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphate(3-)
annotated property: has_exact_synonym
annotated target: tetraoxophosphate(3-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphate(3-)
annotated property: has_exact_synonym
annotated target: tetraoxophosphate(V)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphate(3-)
annotated property: has_related_synonym
annotated target: Orthophosphate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phosphate(3-)
annotated property: has_related_synonym
annotated target: PHOSPHATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: phosphate(3-)
annotated property: has_related_synonym
annotated target: PO4(3-)
database_cross_reference: IUPAC

Axiom
annotated source: phosphate(3-)
annotated property: has_related_synonym
annotated target: Phosphate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phosphate(3-)
annotated property: has_related_synonym
annotated target: [PO4](3-)
database_cross_reference: IUPAC

hydrogen cyanide
type: Class
subclass of: hydracid
subclass of: one-carbon compound

sulfur dioxide
type: Class
subclass of: sulfur oxide

inorganic calcium salt
type: Class
subclass of: mineral nutrient
subclass of: inorganic salt

5beta-cholane
type: Class
subclass of: cholane
charge: 0
formula: C24H42
inchi: InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1
inchikey: QSHQKIURKJITMZ-OBUPQJQESA-N
mass: 330.59028
monoisotopicmass: 330.32865
database_cross_reference: Beilstein:2048472
has_exact_synonym: 5beta-cholane
has_obo_namespace: chebi_ontology
id: CHEBI:20664
in_subset: 3 STAR

Axiom
annotated source: 5beta-cholane
annotated property: database_cross_reference
annotated target: Beilstein:2048472
source: Beilstein

Axiom
annotated source: 5beta-cholane
annotated property: has_exact_synonym
annotated target: 5beta-cholane
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

N-acylglucosamine
type: Class
subclass of: N-acyl-hexosamine
subclass of: glucosamines

N-acyl-hexosamine
type: Class
subclass of: hexosamine

N-methyl-amino acid
type: Class
subclass of: amino acid derivative

N-methylglycines
type: Class
subclass of: N-alkylglycine

acetamides
type: Class
subclass of: carboxamide

acyl group
type: Class
subclass of: organic group
definition: An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.
has_exact_synonym: acyl group
has_exact_synonym: alkanoyl
has_obo_namespace: chebi_ontology
has_related_synonym: acyl groups
has_related_synonym: alkanoyl group
has_related_synonym: groupe acyle
id: CHEBI:22221
in_subset: 3 STAR

Axiom
annotated source: acyl group
annotated property: has_exact_synonym
annotated target: acyl group
database_cross_reference: IUPAC

Axiom
annotated source: acyl group
annotated property: has_exact_synonym
annotated target: alkanoyl
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: acyl group
annotated property: has_related_synonym
annotated target: acyl groups
database_cross_reference: ChEBI

Axiom
annotated source: acyl group
annotated property: has_related_synonym
annotated target: alkanoyl group
database_cross_reference: ChEBI

Axiom
annotated source: acyl group
annotated property: has_related_synonym
annotated target: groupe acyle
database_cross_reference: IUPAC

adenosine phosphate
type: Class
subclass of: adenyl ribonucleotide

alkaline earth metal atom
type: Class
subclass of: main group element atom
subclass of: metal atom
subclass of: s-block element atom

alkali metal atom
type: Class
subclass of: main group element atom
subclass of: metal atom
subclass of: s-block element atom
has_exact_synonym: alkali metals
has_obo_namespace: chebi_ontology
has_related_synonym: Alkalimetall
has_related_synonym: Alkalimetalle
has_related_synonym: alkali metal
has_related_synonym: metal alcalin
has_related_synonym: metal alcalino
has_related_synonym: metales alcalinos
has_related_synonym: metaux alcalins
id: CHEBI:22314
in_subset: 3 STAR

Axiom
annotated source: alkali metal atom
annotated property: has_exact_synonym
annotated target: alkali metals
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: alkali metal atom
annotated property: has_related_synonym
annotated target: Alkalimetall
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: has_related_synonym
annotated target: Alkalimetalle
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: has_related_synonym
annotated target: alkali metal
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: has_related_synonym
annotated target: metal alcalin
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: has_related_synonym
annotated target: metal alcalino
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: has_related_synonym
annotated target: metales alcalinos
database_cross_reference: ChEBI

Axiom
annotated source: alkali metal atom
annotated property: has_related_synonym
annotated target: metaux alcalins
database_cross_reference: ChEBI

alkaloid
type: Class
subclass of: independent continuant
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has role
  some values from: metabolite
definition: Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.
database_cross_reference: Wikipedia:Alkaloid
has_exact_synonym: Alkaloid
has_exact_synonym: alkaloids
has_obo_namespace: chebi_ontology
has_related_synonym: Alkaloide
has_related_synonym: alcaloide
has_related_synonym: alcaloides
id: CHEBI:22315
in_subset: 3 STAR

Axiom
annotated source: alkaloid
annotated property: has_exact_synonym
annotated target: Alkaloid
database_cross_reference: ChEBI

Axiom
annotated source: alkaloid
annotated property: has_exact_synonym
annotated target: alkaloids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: alkaloid
annotated property: has_related_synonym
annotated target: Alkaloide
database_cross_reference: ChEBI

Axiom
annotated source: alkaloid
annotated property: has_related_synonym
annotated target: alcaloide
database_cross_reference: ChEBI

Axiom
annotated source: alkaloid
annotated property: has_related_synonym
annotated target: alcaloides
database_cross_reference: ChEBI

alkyl group
type: Class
subclass of: hydrocarbyl group

alkylamines
type: Class
subclass of: amine

aminoglycan
type: Class
subclass of: organonitrogen compound
subclass of: polysaccharide derivative
has_obo_namespace: chebi_ontology
has_related_synonym: aminoglycans
id: CHEBI:22506
in_subset: 3 STAR

Axiom
annotated source: aminoglycan
annotated property: has_related_synonym
annotated target: aminoglycans
database_cross_reference: ChEBI

anion
type: Class
subclass of: ion
definition: A monoatomic or polyatomic species having one or more elementary charges of the electron.
has_exact_synonym: Anion
has_exact_synonym: anion
has_obo_namespace: chebi_ontology
has_related_synonym: Anionen
has_related_synonym: aniones
has_related_synonym: anions
id: CHEBI:22563
in_subset: 3 STAR

Axiom
annotated source: anion
annotated property: has_exact_synonym
annotated target: Anion
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: has_exact_synonym
annotated target: anion
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: has_exact_synonym
annotated target: anion
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: anion
annotated property: has_related_synonym
annotated target: Anionen
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: has_related_synonym
annotated target: aniones
database_cross_reference: ChEBI

Axiom
annotated source: anion
annotated property: has_related_synonym
annotated target: anions
database_cross_reference: IUPAC

antioxidant
type: Class
subclass of: chemical role
definition: A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
has_obo_namespace: chebi_ontology
has_related_synonym: antioxidants
has_related_synonym: antioxydant
has_related_synonym: antoxidant
id: CHEBI:22586
in_subset: 3 STAR

Axiom
annotated source: antioxidant
annotated property: has_related_synonym
annotated target: antioxidants
database_cross_reference: ChEBI

Axiom
annotated source: antioxidant
annotated property: has_related_synonym
annotated target: antioxydant
database_cross_reference: ChEBI

Axiom
annotated source: antioxidant
annotated property: has_related_synonym
annotated target: antoxidant
database_cross_reference: ChEBI

arsenate ion
type: Class
subclass of: arsenic oxoanion

arsenic molecular entity
type: Class
subclass of: pnictogen molecular entity

base
type: Class
subclass of: chemical role
definition: A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
database_cross_reference: KEGG:C00701
has_exact_synonym: Base
has_exact_synonym: base
has_obo_namespace: chebi_ontology
has_related_synonym: Base1
has_related_synonym: Base2
has_related_synonym: Basen
has_related_synonym: Nucleobase
has_related_synonym: bases
id: CHEBI:22695
in_subset: 3 STAR

Axiom
annotated source: base
annotated property: has_exact_synonym
annotated target: Base
database_cross_reference: ChEBI

Axiom
annotated source: base
annotated property: has_exact_synonym
annotated target: base
database_cross_reference: ChEBI

Axiom
annotated source: base
annotated property: has_exact_synonym
annotated target: base
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: base
annotated property: has_related_synonym
annotated target: Base1
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: base
annotated property: has_related_synonym
annotated target: Base2
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: base
annotated property: has_related_synonym
annotated target: Basen
database_cross_reference: ChEBI

Axiom
annotated source: base
annotated property: has_related_synonym
annotated target: Nucleobase
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: base
annotated property: has_related_synonym
annotated target: bases
database_cross_reference: ChEBI

benzenes
type: Class
subclass of: benzenoid aromatic compound

benzoates
type: Class
subclass of: monocarboxylic acid anion
subclass of: aromatic carboxylate

benzopyrrole
type: Class
subclass of: organic heterobicyclic compound
subclass of: organonitrogen heterocyclic compound
subclass of: polycyclic heteroarene
has_obo_namespace: chebi_ontology
has_related_synonym: benzopyrroles
id: CHEBI:22728
in_subset: 3 STAR

Axiom
annotated source: benzopyrrole
annotated property: has_related_synonym
annotated target: benzopyrroles
database_cross_reference: ChEBI

bile salt
type: Class
subclass of: cholanoid
subclass of: organic sodium salt
definition: A sodium salt of the conjugate of any bile acid with either glycine or taurine.
database_cross_reference: KEGG:C01558
has_obo_namespace: chebi_ontology
has_related_synonym: Bile acid
has_related_synonym: bile salts
id: CHEBI:22868
in_subset: 3 STAR

Axiom
annotated source: bile salt
annotated property: has_related_synonym
annotated target: Bile acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bile salt
annotated property: has_related_synonym
annotated target: bile salts
database_cross_reference: ChEBI

branched-chain amino acid
type: Class
subclass of: amino acid

bromine atom
type: Class
subclass of: halogen

cadmium atom
type: Class
subclass of: zinc group element atom

calcium atom
type: Class
subclass of: alkaline earth metal atom

calcium molecular entity
type: Class
subclass of: alkaline earth molecular entity

carbamate ester
type: Class
subclass of: carboxylic ester

carbamoyl group
type: Class
subclass of: univalent carboacyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carbamic acid
definition: The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid.
charge: 0
formula: CH2NO
mass: 44.03272
monoisotopicmass: 44.01364
smiles: *C(N)=O
database_cross_reference: PMID:24168430
has_exact_synonym: carbamoyl
has_obo_namespace: chebi_ontology
has_related_synonym: -C(O)NH2
has_related_synonym: -CONH2
has_related_synonym: aminocarbonyl
has_related_synonym: carbamyl
has_related_synonym: carbamyl group
has_related_synonym: carboxamide
id: CHEBI:23004
in_subset: 3 STAR

Axiom
annotated source: carbamoyl group
annotated property: database_cross_reference
annotated target: PMID:24168430
source: Europe PMC

Axiom
annotated source: carbamoyl group
annotated property: has_exact_synonym
annotated target: carbamoyl
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbamoyl group
annotated property: has_related_synonym
annotated target: -C(O)NH2
database_cross_reference: ChEBI

Axiom
annotated source: carbamoyl group
annotated property: has_related_synonym
annotated target: -CONH2
database_cross_reference: IUPAC

Axiom
annotated source: carbamoyl group
annotated property: has_related_synonym
annotated target: aminocarbonyl
database_cross_reference: IUPAC

Axiom
annotated source: carbamoyl group
annotated property: has_related_synonym
annotated target: carbamyl
database_cross_reference: ChEBI

Axiom
annotated source: carbamoyl group
annotated property: has_related_synonym
annotated target: carbamyl group
database_cross_reference: ChEBI

Axiom
annotated source: carbamoyl group
annotated property: has_related_synonym
annotated target: carboxamide
database_cross_reference: IUPAC

carbon oxide
type: Class
subclass of: organic oxide
subclass of: organooxygen compound

carbonates
type: Class
subclass of: organooxygen compound

carbonyl group
type: Class
subclass of: organodiyl group
charge: 0
formula: CO
mass: 28.01010
monoisotopicmass: 27.99491
smiles: O=C(*)*
has_exact_synonym: carbonyl
has_exact_synonym: carbonyl group
has_obo_namespace: chebi_ontology
has_related_synonym: >C=O
id: CHEBI:23019
in_subset: 3 STAR

Axiom
annotated source: carbonyl group
annotated property: has_exact_synonym
annotated target: carbonyl
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbonyl group
annotated property: has_exact_synonym
annotated target: carbonyl group
database_cross_reference: ChEBI

Axiom
annotated source: carbonyl group
annotated property: has_exact_synonym
annotated target: carbonyl group
database_cross_reference: UniProt

Axiom
annotated source: carbonyl group
annotated property: has_related_synonym
annotated target: >C=O
database_cross_reference: IUPAC

carotene
type: Class
subclass of: tetraterpene

epoxycarotenoid
type: Class
subclass of: xanthophyll
subclass of: epoxide

carotenoid
type: Class
subclass of: tetraterpenoid

carotenol
type: Class
subclass of: xanthophyll

chloride salt
type: Class
subclass of: chlorine molecular entity
subclass of: halide salt

chlorine atom
type: Class
subclass of: halogen

chlorine molecular entity
type: Class
subclass of: halogen molecular entity

chromium molecular entity
type: Class
subclass of: chromium group molecular entity

cofactor
type: Class
subclass of: biochemical role
definition: An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
database_cross_reference: Wikipedia:Cofactor_(biochemistry)
has_exact_synonym: cofactor
has_exact_synonym: cofactors
has_obo_namespace: chebi_ontology
id: CHEBI:23357
in_subset: 3 STAR

Axiom
annotated source: cofactor
annotated property: has_exact_synonym
annotated target: cofactor
database_cross_reference: IUPAC

Axiom
annotated source: cofactor
annotated property: has_exact_synonym
annotated target: cofactors
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

molecular entity
type: Class
subclass of: chemical entity
definition: Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
has_exact_synonym: molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: entidad molecular
has_related_synonym: entidades moleculares
has_related_synonym: entite moleculaire
has_related_synonym: molecular entities
has_related_synonym: molekulare Entitaet
id: CHEBI:23367
in_subset: 3 STAR

Axiom
annotated source: molecular entity
annotated property: has_exact_synonym
annotated target: molecular entity
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: molecular entity
annotated property: has_related_synonym
annotated target: entidad molecular
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: has_related_synonym
annotated target: entidades moleculares
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: has_related_synonym
annotated target: entite moleculaire
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: has_related_synonym
annotated target: molecular entities
database_cross_reference: IUPAC

Axiom
annotated source: molecular entity
annotated property: has_related_synonym
annotated target: molekulare Entitaet
database_cross_reference: ChEBI

copper molecular entity
type: Class
subclass of: copper group molecular entity

cyclic peptide
type: Class
subclass of: peptide
has_obo_namespace: chebi_ontology
has_related_synonym: Cyclopeptid
has_related_synonym: Zyklopeptid
has_related_synonym: cyclic peptides
has_related_synonym: peptide cyclique
has_related_synonym: peptido ciclico
id: CHEBI:23449
in_subset: 3 STAR

Axiom
annotated source: cyclic peptide
annotated property: has_related_synonym
annotated target: Cyclopeptid
database_cross_reference: ChEBI

Axiom
annotated source: cyclic peptide
annotated property: has_related_synonym
annotated target: Zyklopeptid
database_cross_reference: ChEBI

Axiom
annotated source: cyclic peptide
annotated property: has_related_synonym
annotated target: cyclic peptides
database_cross_reference: ChEBI

Axiom
annotated source: cyclic peptide
annotated property: has_related_synonym
annotated target: peptide cyclique
database_cross_reference: IUPAC

Axiom
annotated source: cyclic peptide
annotated property: has_related_synonym
annotated target: peptido ciclico
database_cross_reference: IUPAC

diol
type: Class
subclass of: polyol

drug
type: Class
subclass of: pharmaceutical
definition: Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
has_obo_namespace: chebi_ontology
has_related_synonym: drugs
has_related_synonym: medicine
id: CHEBI:23888
in_subset: 3 STAR

Axiom
annotated source: drug
annotated property: has_related_synonym
annotated target: drugs
database_cross_reference: ChEBI

Axiom
annotated source: drug
annotated property: has_related_synonym
annotated target: medicine
database_cross_reference: ChEBI

monoatomic anion
type: Class
subclass of: anion
subclass of: monoatomic ion

monoatomic cation
type: Class
subclass of: monoatomic ion
subclass of: cation
has_obo_namespace: chebi_ontology
has_related_synonym: monoatomic cations
id: CHEBI:23906
in_subset: 3 STAR

Axiom
annotated source: monoatomic cation
annotated property: has_related_synonym
annotated target: monoatomic cations
database_cross_reference: ChEBI

enzyme inhibitor
type: Class
subclass of: inhibitor
subclass of: biochemical role
definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
has_exact_synonym: enzyme inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: enzyme inhibitors
has_related_synonym: inhibidor enzimatico
has_related_synonym: inhibidores enzimaticos
has_related_synonym: inhibiteur enzymatique
has_related_synonym: inhibiteurs enzymatiques
id: CHEBI:23924
in_subset: 3 STAR

Axiom
annotated source: enzyme inhibitor
annotated property: has_exact_synonym
annotated target: enzyme inhibitor
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: enzyme inhibitor
annotated property: has_related_synonym
annotated target: enzyme inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: has_related_synonym
annotated target: inhibidor enzimatico
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: has_related_synonym
annotated target: inhibidores enzimaticos
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: has_related_synonym
annotated target: inhibiteur enzymatique
database_cross_reference: ChEBI

Axiom
annotated source: enzyme inhibitor
annotated property: has_related_synonym
annotated target: inhibiteurs enzymatiques
database_cross_reference: ChEBI

ethanols
type: Class
subclass of: primary alcohol

fluorine atom
type: Class
subclass of: halogen

fluorine molecular entity
type: Class
subclass of: halogen molecular entity

glucosamines
type: Class
subclass of: hexosamine

glycine derivative
type: Class
subclass of: proteinogenic amino acid derivative

glycogens
type: Class
subclass of: glucan
has_obo_namespace: chebi_ontology
id: CHEBI:24384
in_subset: 3 STAR

chemical entity
type: Class
subclass of: material entity
definition: A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
has_exact_synonym: chemical entity
has_obo_namespace: chebi_ontology
id: CHEBI:24431
in_subset: 3 STAR

Axiom
annotated source: chemical entity
annotated property: has_exact_synonym
annotated target: chemical entity
database_cross_reference: UniProt

biological role
type: Class
subclass of: realizable
subclass of: role
subclass of: PATO_0000001
definition: A role played by the molecular entity or part thereof within a biological context.
has_obo_namespace: chebi_ontology
has_related_synonym: biological function
id: CHEBI:24432
in_subset: 3 STAR

Axiom
annotated source: biological role
annotated property: has_related_synonym
annotated target: biological function
database_cross_reference: ChEBI

group
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: atom
definition: A defined linked collection of atoms or a single atom within a molecular entity.
has_exact_synonym: group
has_obo_namespace: chebi_ontology
has_related_synonym: Gruppe
has_related_synonym: Rest
has_related_synonym: groupe
has_related_synonym: grupo
has_related_synonym: grupos
id: CHEBI:24433
in_subset: 3 STAR

Axiom
annotated source: group
annotated property: has_exact_synonym
annotated target: group
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: group
annotated property: has_related_synonym
annotated target: Gruppe
database_cross_reference: ChEBI

Axiom
annotated source: group
annotated property: has_related_synonym
annotated target: Rest
database_cross_reference: ChEBI

Axiom
annotated source: group
annotated property: has_related_synonym
annotated target: groupe
database_cross_reference: IUPAC

Axiom
annotated source: group
annotated property: has_related_synonym
annotated target: grupo
database_cross_reference: IUPAC

Axiom
annotated source: group
annotated property: has_related_synonym
annotated target: grupos
database_cross_reference: IUPAC

guanidines
type: Class
subclass of: organonitrogen compound

guanosine phosphate
type: Class
subclass of: guanyl ribonucleotide

halogen molecular entity
type: Class
subclass of: p-block molecular entity

halogen
type: Class
subclass of: nonmetal atom
subclass of: p-block element atom

organic heterocyclic compound
type: Class
subclass of: heteroorganic entity
subclass of: organic cyclic compound
subclass of: heterocyclic compound
definition: A cyclic compound having as ring members atoms of carbon and at least of one other element.
has_obo_namespace: chebi_ontology
has_related_synonym: organic heterocycle
has_related_synonym: organic heterocyclic compounds
id: CHEBI:24532
in_subset: 3 STAR

Axiom
annotated source: organic heterocyclic compound
annotated property: has_related_synonym
annotated target: organic heterocycle
database_cross_reference: ChEBI

Axiom
annotated source: organic heterocyclic compound
annotated property: has_related_synonym
annotated target: organic heterocyclic compounds
database_cross_reference: ChEBI

heterodetic cyclic peptide
type: Class
subclass of: cyclic peptide
definition: A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond.
has_exact_synonym: heterodetic cyclic peptide
has_obo_namespace: chebi_ontology
has_related_synonym: heterodetic cyclic peptides
has_related_synonym: peptide cyclique heterodetique
has_related_synonym: peptido ciclico heterodetico
id: CHEBI:24533
in_subset: 3 STAR

Axiom
annotated source: heterodetic cyclic peptide
annotated property: has_exact_synonym
annotated target: heterodetic cyclic peptide
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: heterodetic cyclic peptide
annotated property: has_related_synonym
annotated target: heterodetic cyclic peptides
database_cross_reference: ChEBI

Axiom
annotated source: heterodetic cyclic peptide
annotated property: has_related_synonym
annotated target: peptide cyclique heterodetique
database_cross_reference: IUPAC

Axiom
annotated source: heterodetic cyclic peptide
annotated property: has_related_synonym
annotated target: peptido ciclico heterodetico
database_cross_reference: IUPAC

hexosamine
type: Class
subclass of: amino monosaccharide

hormone
type: Class
subclass of: molecular messenger
subclass of: agonist
definition: Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
has_obo_namespace: chebi_ontology
has_related_synonym: endocrine
has_related_synonym: hormones
id: CHEBI:24621
in_subset: 3 STAR

Axiom
annotated source: hormone
annotated property: has_related_synonym
annotated target: endocrine
database_cross_reference: ChEBI

Axiom
annotated source: hormone
annotated property: has_related_synonym
annotated target: hormones
database_cross_reference: ChEBI

hydrocarbon
type: Class
subclass of: organic fundamental parent

proton
type: Class
subclass of: hydron
subclass of: nucleon

hydroxides
type: Class
subclass of: oxygen molecular entity
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydroxy group
definition: Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).
has_obo_namespace: chebi_ontology
id: CHEBI:24651
in_subset: 3 STAR

hydroxy-5beta-cholanic acid
type: Class
subclass of: organic hydroxy compound
subclass of: 5beta-cholanic acids
subclass of: Restriction
  on property: has functional parent
  some values from: 5beta-cholanic acid
definition: Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position.
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxy-5beta-cholanic acids
id: CHEBI:24663
in_subset: 3 STAR

Axiom
annotated source: hydroxy-5beta-cholanic acid
annotated property: has_related_synonym
annotated target: hydroxy-5beta-cholanic acids
database_cross_reference: ChEBI

hydroxybenzoate
type: Class
subclass of: benzoates
subclass of: hydroxy monocarboxylic acid anion

indoles
type: Class
subclass of: benzopyrrole
definition: Any compound containing an indole skeleton.
has_obo_namespace: chebi_ontology
id: CHEBI:24828
in_subset: 3 STAR

oxoacid
type: Class
subclass of: independent continuant
subclass of: hydroxides
subclass of: Restriction
  on property: has role
  some values from: Bronsted acid
definition: A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
has_exact_synonym: oxoacid
has_exact_synonym: oxoacids
has_obo_namespace: chebi_ontology
has_related_synonym: oxacids
has_related_synonym: oxiacids
has_related_synonym: oxo acid
has_related_synonym: oxy-acids
has_related_synonym: oxyacids
id: CHEBI:24833
in_subset: 3 STAR

Axiom
annotated source: oxoacid
annotated property: has_exact_synonym
annotated target: oxoacid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: oxoacid
annotated property: has_exact_synonym
annotated target: oxoacids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: oxoacid
annotated property: has_related_synonym
annotated target: oxacids
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: has_related_synonym
annotated target: oxiacids
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: has_related_synonym
annotated target: oxo acid
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: has_related_synonym
annotated target: oxy-acids
database_cross_reference: ChEBI

Axiom
annotated source: oxoacid
annotated property: has_related_synonym
annotated target: oxyacids
database_cross_reference: ChEBI

inorganic anion
type: Class
subclass of: anion
subclass of: inorganic ion
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic anions
id: CHEBI:24834
in_subset: 3 STAR

Axiom
annotated source: inorganic anion
annotated property: has_related_synonym
annotated target: inorganic anions
database_cross_reference: ChEBI

inorganic molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity that contains no carbon.
has_obo_namespace: chebi_ontology
has_related_synonym: anorganische Verbindungen
has_related_synonym: inorganic compounds
has_related_synonym: inorganic entity
has_related_synonym: inorganic molecular entities
has_related_synonym: inorganics
id: CHEBI:24835
in_subset: 3 STAR

Axiom
annotated source: inorganic molecular entity
annotated property: has_related_synonym
annotated target: anorganische Verbindungen
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: has_related_synonym
annotated target: inorganic compounds
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: has_related_synonym
annotated target: inorganic entity
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: has_related_synonym
annotated target: inorganic molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: inorganic molecular entity
annotated property: has_related_synonym
annotated target: inorganics
database_cross_reference: ChEBI

inorganic oxide
type: Class
subclass of: inorganic molecular entity
subclass of: oxide
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic oxides
id: CHEBI:24836
in_subset: 3 STAR

Axiom
annotated source: inorganic oxide
annotated property: has_related_synonym
annotated target: inorganic oxides
database_cross_reference: ChEBI

inorganic peroxide
type: Class
subclass of: inorganic oxide
subclass of: peroxides

inorganic salt
type: Class
subclass of: inorganic molecular entity
subclass of: salt

inorganic sulfate salt
type: Class
subclass of: inorganic salt
subclass of: sulfate salt

salt
type: Class
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has part
  some values from: anion
subclass of: Restriction
  on property: has part
  some values from: cation
definition: A salt is an assembly of cations and anions.
has_exact_synonym: salt
has_obo_namespace: chebi_ontology
has_related_synonym: Salz
has_related_synonym: Salze
has_related_synonym: ionic compound
has_related_synonym: ionic compounds
has_related_synonym: sal
has_related_synonym: sales
has_related_synonym: salts
has_related_synonym: sel
has_related_synonym: sels
id: CHEBI:24866
in_subset: 3 STAR

Axiom
annotated source: salt
annotated property: has_exact_synonym
annotated target: salt
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: Salz
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: Salze
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: ionic compound
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: ionic compounds
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: sal
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: sales
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: salts
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: sel
database_cross_reference: ChEBI

Axiom
annotated source: salt
annotated property: has_related_synonym
annotated target: sels
database_cross_reference: ChEBI

monoatomic ion
type: Class
subclass of: ion
subclass of: monoatomic entity
has_obo_namespace: chebi_ontology
has_related_synonym: monoatomic ions
id: CHEBI:24867
in_subset: 3 STAR

Axiom
annotated source: monoatomic ion
annotated property: has_related_synonym
annotated target: monoatomic ions
database_cross_reference: ChEBI

organic salt
type: Class
subclass of: salt
has_obo_namespace: chebi_ontology
has_related_synonym: organic salts
has_related_synonym: organisches Salz
id: CHEBI:24868
in_subset: 3 STAR

Axiom
annotated source: organic salt
annotated property: has_related_synonym
annotated target: organic salts
database_cross_reference: ChEBI

Axiom
annotated source: organic salt
annotated property: has_related_synonym
annotated target: organisches Salz
database_cross_reference: ChEBI

ion
type: Class
subclass of: molecular entity
definition: A molecular entity having a net electric charge.
has_exact_synonym: Ion
has_exact_synonym: ion
has_obo_namespace: chebi_ontology
has_related_synonym: Ionen
has_related_synonym: iones
has_related_synonym: ions
id: CHEBI:24870
in_subset: 3 STAR

Axiom
annotated source: ion
annotated property: has_exact_synonym
annotated target: Ion
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: has_exact_synonym
annotated target: ion
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: has_exact_synonym
annotated target: ion
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: ion
annotated property: has_related_synonym
annotated target: Ionen
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: has_related_synonym
annotated target: iones
database_cross_reference: ChEBI

Axiom
annotated source: ion
annotated property: has_related_synonym
annotated target: ions
database_cross_reference: ChEBI

iron molecular entity
type: Class
subclass of: iron group molecular entity
has_exact_synonym: iron molecular entity
has_related_synonym: iron compounds
has_related_synonym: iron molecular entities

isoprenoid
type: Class
subclass of: lipid

lead atom
type: Class
subclass of: carbon group element atom
subclass of: metal atom

leucine
type: Class
subclass of: branched-chain amino acid
subclass of: alpha-amino acid

linear tetrapyrrole
type: Class
subclass of: tetrapyrrole
has_obo_namespace: chebi_ontology
id: CHEBI:25046
in_subset: 1 STAR

magnesium atom
type: Class
subclass of: alkaline earth metal atom

magnesium molecular entity
type: Class
subclass of: alkaline earth molecular entity

magnesium porphyrin
type: Class
subclass of: metalloporphyrin
subclass of: magnesium tetrapyrrole

manganese molecular entity
type: Class
subclass of: manganese group molecular entity

metabolite
type: Class
subclass of: biochemical role
definition: Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
has_alternative_id: CHEBI:26619
has_alternative_id: CHEBI:35220
has_exact_synonym: metabolite
has_obo_namespace: chebi_ontology
has_related_synonym: metabolites
has_related_synonym: primary metabolites
has_related_synonym: secondary metabolites
id: CHEBI:25212
in_subset: 3 STAR

Axiom
annotated source: metabolite
annotated property: has_exact_synonym
annotated target: metabolite
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: metabolite
annotated property: has_related_synonym
annotated target: metabolites
database_cross_reference: ChEBI

Axiom
annotated source: metabolite
annotated property: has_related_synonym
annotated target: primary metabolites
database_cross_reference: ChEBI

Axiom
annotated source: metabolite
annotated property: has_related_synonym
annotated target: secondary metabolites
database_cross_reference: ChEBI

metal cation
type: Class
subclass of: monoatomic cation
subclass of: inorganic cation
has_obo_namespace: chebi_ontology
has_related_synonym: a metal cation
has_related_synonym: metal cations
id: CHEBI:25213
in_subset: 3 STAR

Axiom
annotated source: metal cation
annotated property: has_related_synonym
annotated target: a metal cation
database_cross_reference: UniProt

Axiom
annotated source: metal cation
annotated property: has_related_synonym
annotated target: metal cations
database_cross_reference: ChEBI

metalloporphyrin
type: Class
subclass of: porphyrins
subclass of: coordination entity
subclass of: metallotetrapyrrole

methyl ester
type: Class
subclass of: carboxylic ester

methylamines
type: Class
subclass of: alkylamines

mitochondrial respiratory-chain inhibitor
type: Class
subclass of: respiratory-chain inhibitor

elemental molecule
type: Class
subclass of: molecule
subclass of: elemental molecular entity
definition: A molecule all atoms of which have the same atomic number.
has_obo_namespace: chebi_ontology
has_related_synonym: homoatomic molecule
has_related_synonym: homoatomic molecules
id: CHEBI:25362
in_subset: 3 STAR

Axiom
annotated source: elemental molecule
annotated property: has_related_synonym
annotated target: homoatomic molecule
database_cross_reference: ChEBI

Axiom
annotated source: elemental molecule
annotated property: has_related_synonym
annotated target: homoatomic molecules
database_cross_reference: ChEBI

molecule
type: Class
subclass of: polyatomic entity
definition: Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.
has_exact_synonym: molecule
has_obo_namespace: chebi_ontology
has_related_synonym: Molekuel
has_related_synonym: molecula
has_related_synonym: molecules
has_related_synonym: neutral molecular compounds
id: CHEBI:25367
in_subset: 3 STAR

Axiom
annotated source: molecule
annotated property: has_exact_synonym
annotated target: molecule
database_cross_reference: IUPAC

Axiom
annotated source: molecule
annotated property: has_related_synonym
annotated target: Molekuel
database_cross_reference: ChEBI

Axiom
annotated source: molecule
annotated property: has_related_synonym
annotated target: molecula
database_cross_reference: IUPAC

Axiom
annotated source: molecule
annotated property: has_related_synonym
annotated target: molecules
database_cross_reference: IUPAC

Axiom
annotated source: molecule
annotated property: has_related_synonym
annotated target: neutral molecular compounds
database_cross_reference: IUPAC

monoamine molecular messenger
type: Class
subclass of: monoamine
subclass of: Restriction
  on property: has role
  some values from: molecular messenger
definition: A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
has_obo_namespace: chebi_ontology
has_related_synonym: monamines
has_related_synonym: monoamines
id: CHEBI:25375
in_subset: 3 STAR

Axiom
annotated source: monoamine molecular messenger
annotated property: has_related_synonym
annotated target: monamines
database_cross_reference: ChEBI

Axiom
annotated source: monoamine molecular messenger
annotated property: has_related_synonym
annotated target: monoamines
database_cross_reference: ChEBI

monocarboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: monocarboxylic acid anion
definition: An oxoacid containing a single carboxy group.
has_obo_namespace: chebi_ontology
has_related_synonym: monocarboxylic acids
id: CHEBI:25384
in_subset: 3 STAR

Axiom
annotated source: monocarboxylic acid
annotated property: has_related_synonym
annotated target: monocarboxylic acids
database_cross_reference: ChEBI

monohydroxybenzoate
type: Class
subclass of: hydroxybenzoate

monoatomic monocation
type: Class
subclass of: monoatomic cation
charge: +1
mass: 0.00000
smiles: [*+]
has_obo_namespace: chebi_ontology
has_related_synonym: monoatomic monocations
has_related_synonym: monovalent inorganic cations
id: CHEBI:25414
in_subset: 3 STAR

Axiom
annotated source: monoatomic monocation
annotated property: has_related_synonym
annotated target: monoatomic monocations
database_cross_reference: ChEBI

Axiom
annotated source: monoatomic monocation
annotated property: has_related_synonym
annotated target: monovalent inorganic cations
database_cross_reference: ChEBI

monoatomic polycation
type: Class
subclass of: monoatomic cation

mutagen
type: Class
subclass of: genotoxin

mycotoxin
type: Class
subclass of: toxin
subclass of: fungal metabolite

naphthalenes
type: Class
subclass of: benzenoid aromatic compound
subclass of: carbobicyclic compound

neoxanthin
type: Class
subclass of: epoxycarotenol
subclass of: allenes

neurotransmitter
type: Class
subclass of: molecular messenger
definition: An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
database_cross_reference: Wikipedia:Neurotransmitter
has_obo_namespace: chebi_ontology
has_related_synonym: neurotransmitters
id: CHEBI:25512
in_subset: 3 STAR

Axiom
annotated source: neurotransmitter
annotated property: has_related_synonym
annotated target: neurotransmitters
database_cross_reference: ChEBI

NADP
type: Class
subclass of: NAD(P)

NAD(P)
type: Class
subclass of: nicotinamide dinucleotide
subclass of: adenyl nucleotide

nicotinamide nucleotide
type: Class
subclass of: pyridine nucleotide

nitrogen atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: pnictogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: N
mass: 14.007
monoisotopicmass: 14.00307
database_cross_reference: WebElements:N
has_exact_synonym: nitrogen
has_obo_namespace: chebi_ontology
has_related_synonym: 7N
has_related_synonym: N
has_related_synonym: Stickstoff
has_related_synonym: azote
has_related_synonym: nitrogen
has_related_synonym: nitrogeno
id: CHEBI:25555
in_subset: 3 STAR

Axiom
annotated source: nitrogen atom
annotated property: has_exact_synonym
annotated target: nitrogen
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: nitrogen atom
annotated property: has_related_synonym
annotated target: 7N
database_cross_reference: IUPAC

Axiom
annotated source: nitrogen atom
annotated property: has_related_synonym
annotated target: N
database_cross_reference: IUPAC

Axiom
annotated source: nitrogen atom
annotated property: has_related_synonym
annotated target: Stickstoff
database_cross_reference: ChEBI

Axiom
annotated source: nitrogen atom
annotated property: has_related_synonym
annotated target: azote
database_cross_reference: IUPAC

Axiom
annotated source: nitrogen atom
annotated property: has_related_synonym
annotated target: nitrogen
database_cross_reference: ChEBI

Axiom
annotated source: nitrogen atom
annotated property: has_related_synonym
annotated target: nitrogeno
database_cross_reference: ChEBI

nitrous acid
type: Class
subclass of: nitrogen oxoacid

nonmetal atom
type: Class
subclass of: atom
has_exact_synonym: nonmetal
has_obo_namespace: chebi_ontology
has_related_synonym: Nichtmetall
has_related_synonym: Nichtmetalle
has_related_synonym: no metal
has_related_synonym: no metales
has_related_synonym: non-metal
has_related_synonym: non-metaux
has_related_synonym: nonmetal
has_related_synonym: nonmetals
id: CHEBI:25585
in_subset: 3 STAR

Axiom
annotated source: nonmetal atom
annotated property: has_exact_synonym
annotated target: nonmetal
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: Nichtmetall
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: Nichtmetalle
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: no metal
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: no metales
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: non-metal
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: non-metaux
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: nonmetal
database_cross_reference: ChEBI

Axiom
annotated source: nonmetal atom
annotated property: has_related_synonym
annotated target: nonmetals
database_cross_reference: ChEBI

nucleoside phosphate
type: Class
subclass of: organic phosphate
subclass of: phosphoric ester
subclass of: nucleobase-containing molecular entity

organic heteromonocyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heteromonocyclic compound

organic anion
type: Class
subclass of: anion
subclass of: organic ion
definition: Any organic ion with a net negative charge.
has_obo_namespace: chebi_ontology
has_related_synonym: organic anions
id: CHEBI:25696
in_subset: 3 STAR

Axiom
annotated source: organic anion
annotated property: has_related_synonym
annotated target: organic anions
database_cross_reference: ChEBI

organic cation
type: Class
subclass of: organic ion
subclass of: cation
definition: Any organic ion with a net positive charge.
has_obo_namespace: chebi_ontology
has_related_synonym: organic cations
id: CHEBI:25697
in_subset: 3 STAR

Axiom
annotated source: organic cation
annotated property: has_related_synonym
annotated target: organic cations
database_cross_reference: ChEBI

ether
type: Class
subclass of: organooxygen compound

organic ion
type: Class
subclass of: ion
subclass of: organic molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: organic ions
id: CHEBI:25699
in_subset: 3 STAR

Axiom
annotated source: organic ion
annotated property: has_related_synonym
annotated target: organic ions
database_cross_reference: ChEBI

organic oxide
type: Class
subclass of: oxide
subclass of: organic molecule

organic phosphate
type: Class
subclass of: organophosphorus compound
subclass of: phosphate

organic sulfate
type: Class
subclass of: sulfates
subclass of: Restriction
  on property: is conjugate acid of
  some values from: organosulfate oxoanion
definition: Compounds of the general formula SO3HOR where R is an organyl group
has_obo_namespace: chebi_ontology
has_related_synonym: organic sulfates
id: CHEBI:25704
in_subset: 3 STAR

Axiom
annotated source: organic sulfate
annotated property: has_related_synonym
annotated target: organic sulfates
database_cross_reference: ChEBI

aliphatic alcohol
type: Class
subclass of: alcohol

organophosphorus compound
type: Class
subclass of: phosphorus molecular entity
subclass of: heteroorganic entity

oxide
type: Class
subclass of: oxygen molecular entity
subclass of: heteroatomic molecular entity
definition: An oxide is a chemical compound of oxygen with other chemical elements.
has_exact_synonym: oxide
has_obo_namespace: chebi_ontology
has_related_synonym: oxides
id: CHEBI:25741
in_subset: 3 STAR

Axiom
annotated source: oxide
annotated property: has_exact_synonym
annotated target: oxide
database_cross_reference: ChEBI

Axiom
annotated source: oxide
annotated property: has_related_synonym
annotated target: oxides
database_cross_reference: ChEBI

oxygen atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: O
inchi: InChI=1S/O
inchikey: QVGXLLKOCUKJST-UHFFFAOYSA-N
mass: 15.99940
monoisotopicmass: 15.99491
smiles: [O]
database_cross_reference: KEGG:C00007
database_cross_reference: WebElements:O
has_exact_synonym: oxygen
has_obo_namespace: chebi_ontology
has_related_synonym: 8O
has_related_synonym: O
has_related_synonym: Sauerstoff
has_related_synonym: oxigeno
has_related_synonym: oxygen
has_related_synonym: oxygene
id: CHEBI:25805
in_subset: 3 STAR

Axiom
annotated source: oxygen atom
annotated property: has_exact_synonym
annotated target: oxygen
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: oxygen atom
annotated property: has_related_synonym
annotated target: 8O
database_cross_reference: IUPAC

Axiom
annotated source: oxygen atom
annotated property: has_related_synonym
annotated target: O
database_cross_reference: IUPAC

Axiom
annotated source: oxygen atom
annotated property: has_related_synonym
annotated target: Sauerstoff
database_cross_reference: ChEBI

Axiom
annotated source: oxygen atom
annotated property: has_related_synonym
annotated target: oxigeno
database_cross_reference: ChEBI

Axiom
annotated source: oxygen atom
annotated property: has_related_synonym
annotated target: oxygen
database_cross_reference: ChEBI

Axiom
annotated source: oxygen atom
annotated property: has_related_synonym
annotated target: oxygene
database_cross_reference: ChEBI

oxygen molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: oxygen atom
has_exact_synonym: oxygen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: oxygen molecular entities
id: CHEBI:25806
in_subset: 3 STAR

Axiom
annotated source: oxygen molecular entity
annotated property: has_exact_synonym
annotated target: oxygen molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: oxygen molecular entity
annotated property: has_related_synonym
annotated target: oxygen molecular entities
database_cross_reference: ChEBI

ozone
type: Class
subclass of: gas molecular entity
subclass of: elemental molecule
subclass of: reactive oxygen species
subclass of: triatomic oxygen

aldopentose phosphate
type: Class
subclass of: aldose phosphate
subclass of: pentose phosphate

peptide hormone
type: Class
subclass of: peptide
subclass of: Restriction
  on property: has role
  some values from: hormone
definition: Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine.
has_obo_namespace: chebi_ontology
has_related_synonym: peptide hormones
has_related_synonym: polypeptide hormone
id: CHEBI:25905
in_subset: 3 STAR

Axiom
annotated source: peptide hormone
annotated property: has_related_synonym
annotated target: peptide hormones
database_cross_reference: ChEBI

Axiom
annotated source: peptide hormone
annotated property: has_related_synonym
annotated target: polypeptide hormone
database_cross_reference: ChEBI

peroxides
type: Class
subclass of: oxide

pesticide
type: Class
subclass of: application

phosphate
type: Class
subclass of: phosphoric acid derivative
definition: Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom.
has_exact_synonym: phosphates
has_obo_namespace: chebi_ontology
has_related_synonym: phosphates
id: CHEBI:26020
in_subset: 3 STAR

Axiom
annotated source: phosphate
annotated property: has_exact_synonym
annotated target: phosphates
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphate
annotated property: has_related_synonym
annotated target: phosphates
database_cross_reference: ChEBI

phosphoric acid
type: Class
subclass of: phosphoric acids
subclass of: Restriction
  on property: has role
  some values from: fertilizer
subclass of: Restriction
  on property: has role
  some values from: solvent
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: has role
  some values from: algal metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: phosphate ion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dihydrogenphosphate
definition: A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom.
charge: 0
formula: H3O4P
inchi: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
inchikey: NBIIXXVUZAFLBC-UHFFFAOYSA-N
mass: 97.99520
monoisotopicmass: 97.97690
smiles: [H]OP(=O)(O[H])O[H]
database_cross_reference: Beilstein:1921286
database_cross_reference: CAS:7664-38-2
database_cross_reference: Drug_Central:4478
database_cross_reference: Gmelin:2000
database_cross_reference: HMDB:HMDB0002142
database_cross_reference: KEGG:C00009
database_cross_reference: KEGG:D05467
database_cross_reference: KNApSAcK:C00007408
database_cross_reference: PMID:11455380
database_cross_reference: PMID:15630224
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17518491
database_cross_reference: PMID:22282755
database_cross_reference: PMID:22333268
database_cross_reference: PMID:22381614
database_cross_reference: PMID:22401268
database_cross_reference: Reaxys:1921286
database_cross_reference: Wikipedia:Phosphoric_Acid
has_exact_synonym: Phosphoric acid
has_exact_synonym: phosphoric acid
has_exact_synonym: tetraoxophosphoric acid
has_exact_synonym: trihydrogen tetraoxophosphate(3-)
has_exact_synonym: trihydroxidooxidophosphorus
has_obo_namespace: chebi_ontology
has_related_synonym: H3PO4
has_related_synonym: Orthophosphoric acid
has_related_synonym: Phosphate
has_related_synonym: Phosphorsaeure
has_related_synonym: Phosphorsaeureloesungen
has_related_synonym: [PO(OH)3]
has_related_synonym: acide phosphorique
has_related_synonym: acidum phosphoricum
has_related_synonym: orthophosphoric acid
id: CHEBI:26078
in_subset: 3 STAR

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: Beilstein:1921286
source: Beilstein

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: CAS:7664-38-2
source: ChemIDplus

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: CAS:7664-38-2
source: KEGG COMPOUND

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: CAS:7664-38-2
source: NIST Chemistry WebBook

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: Drug_Central:4478
source: DrugCentral

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: Gmelin:2000
source: Gmelin

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:11455380
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:15630224
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:17439666
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:17518491
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:22282755
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:22333268
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:22381614
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: PMID:22401268
source: Europe PMC

Axiom
annotated source: phosphoric acid
annotated property: database_cross_reference
annotated target: Reaxys:1921286
source: Reaxys

Axiom
annotated source: phosphoric acid
annotated property: has_exact_synonym
annotated target: Phosphoric acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phosphoric acid
annotated property: has_exact_synonym
annotated target: phosphoric acid
database_cross_reference: IUPAC

Axiom
annotated source: phosphoric acid
annotated property: has_exact_synonym
annotated target: tetraoxophosphoric acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphoric acid
annotated property: has_exact_synonym
annotated target: trihydrogen tetraoxophosphate(3-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphoric acid
annotated property: has_exact_synonym
annotated target: trihydroxidooxidophosphorus
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: H3PO4
database_cross_reference: IUPAC

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: Orthophosphoric acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: Phosphate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: Phosphorsaeure
database_cross_reference: ChEBI

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: Phosphorsaeureloesungen
database_cross_reference: ChEBI

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: [PO(OH)3]
database_cross_reference: IUPAC

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: acide phosphorique
database_cross_reference: ChEBI

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: acidum phosphoricum
database_cross_reference: ChEBI

Axiom
annotated source: phosphoric acid
annotated property: has_related_synonym
annotated target: orthophosphoric acid
database_cross_reference: NIST_Chemistry_WebBook

phosphoric acid derivative
type: Class
subclass of: phosphorus oxoacid derivative
subclass of: Restriction
  on property: has functional parent
  some values from: phosphoric acid
has_obo_namespace: chebi_ontology
id: CHEBI:26079
in_subset: 1 STAR

phosphorus molecular entity
type: Class
subclass of: pnictogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: phosphorus atom
has_obo_namespace: chebi_ontology
has_related_synonym: phosphorus molecular entities
id: CHEBI:26082
in_subset: 3 STAR

Axiom
annotated source: phosphorus molecular entity
annotated property: has_related_synonym
annotated target: phosphorus molecular entities
database_cross_reference: ChEBI

biological pigment
type: Class
subclass of: biophysical role

polar amino acid
type: Class
subclass of: amino acid

polyester macromolecule
type: Class
subclass of: macromolecule
subclass of: ester

polyol
type: Class
subclass of: organic hydroxy compound

porphyrins
type: Class
subclass of: cyclic tetrapyrrole

potassium atom
type: Class
subclass of: alkali metal atom

potassium molecular entity
type: Class
subclass of: alkali metal molecular entity

propane-1,2-diols
type: Class
subclass of: propanediol

propanediol
type: Class
subclass of: glycol

purine nucleoside triphosphate
type: Class
subclass of: nucleoside 5'-triphoshate

purine nucleotide
type: Class
subclass of: purines
subclass of: nucleotide

purine ribonucleoside triphosphate
type: Class
subclass of: ribonucleoside triphosphate
subclass of: purine nucleoside triphosphate

purine ribonucleotide
type: Class
subclass of: purine nucleotide
subclass of: ribonucleotide

purines
type: Class
subclass of: imidazopyrimidine

pyridines
type: Class
subclass of: organic heteromonocyclic compound
subclass of: organonitrogen heterocyclic compound

quinate
type: Class
subclass of: cyclitol carboxylic acid anion

radical
type: Class
subclass of: molecular entity

reactive oxygen species
type: Class
subclass of: oxygen molecular entity

ribonucleotide
type: Class
subclass of: ribose phosphate
subclass of: nucleotide

ribose phosphate
type: Class
subclass of: aldopentose phosphate

saturated fatty acid
type: Class
subclass of: fatty acid

silicic acid
type: Class
subclass of: silicon oxoacid

silicon molecular entity
type: Class
subclass of: carbon group molecular entity

sodium atom
type: Class
subclass of: independent continuant
subclass of: alkali metal atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
charge: 0
formula: Na
inchi: InChI=1S/Na
inchikey: KEAYESYHFKHZAL-UHFFFAOYSA-N
mass: 22.98977
monoisotopicmass: 22.98977
smiles: [Na]
database_cross_reference: CAS:7440-23-5
database_cross_reference: Gmelin:16221
database_cross_reference: KEGG:C01330
database_cross_reference: WebElements:Na
has_exact_synonym: sodium
has_obo_namespace: chebi_ontology
has_related_synonym: 11Na
has_related_synonym: Na
has_related_synonym: Natrium
has_related_synonym: natrium
has_related_synonym: sodio
has_related_synonym: sodium
id: CHEBI:26708
in_subset: 3 STAR

Axiom
annotated source: sodium atom
annotated property: database_cross_reference
annotated target: CAS:7440-23-5
source: ChemIDplus

Axiom
annotated source: sodium atom
annotated property: database_cross_reference
annotated target: Gmelin:16221
source: Gmelin

Axiom
annotated source: sodium atom
annotated property: has_exact_synonym
annotated target: sodium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sodium atom
annotated property: has_related_synonym
annotated target: 11Na
database_cross_reference: IUPAC

Axiom
annotated source: sodium atom
annotated property: has_related_synonym
annotated target: Na
database_cross_reference: IUPAC

Axiom
annotated source: sodium atom
annotated property: has_related_synonym
annotated target: Natrium
database_cross_reference: ChemIDplus

Axiom
annotated source: sodium atom
annotated property: has_related_synonym
annotated target: natrium
database_cross_reference: IUPAC

Axiom
annotated source: sodium atom
annotated property: has_related_synonym
annotated target: sodio
database_cross_reference: ChemIDplus

Axiom
annotated source: sodium atom
annotated property: has_related_synonym
annotated target: sodium
database_cross_reference: ChEBI

sodium chloride
type: Class
subclass of: inorganic chloride
subclass of: inorganic sodium salt

sodium molecular entity
type: Class
subclass of: alkali metal molecular entity
subclass of: Restriction
  on property: has part
  some values from: sodium atom
has_obo_namespace: chebi_ontology
has_related_synonym: sodium compounds
has_related_synonym: sodium molecular entities
id: CHEBI:26712
in_subset: 3 STAR

Axiom
annotated source: sodium molecular entity
annotated property: has_related_synonym
annotated target: sodium compounds
database_cross_reference: ChEBI

Axiom
annotated source: sodium molecular entity
annotated property: has_related_synonym
annotated target: sodium molecular entities
database_cross_reference: ChEBI

sodium salt
type: Class
subclass of: sodium molecular entity
subclass of: alkali metal salt
subclass of: Restriction
  on property: has part
  some values from: sodium(1+)
definition: Any alkali metal salt having sodium(1+) as the cation.
has_obo_namespace: chebi_ontology
has_related_synonym: Natriumsalz
has_related_synonym: Natriumsalze
has_related_synonym: sodium salts
id: CHEBI:26714
in_subset: 3 STAR

Axiom
annotated source: sodium salt
annotated property: has_related_synonym
annotated target: Natriumsalz
database_cross_reference: ChEBI

Axiom
annotated source: sodium salt
annotated property: has_related_synonym
annotated target: Natriumsalze
database_cross_reference: ChEBI

Axiom
annotated source: sodium salt
annotated property: has_related_synonym
annotated target: sodium salts
database_cross_reference: ChEBI

steroid hormone
type: Class
subclass of: independent continuant
subclass of: steroid
subclass of: Restriction
  on property: has role
  some values from: hormone
definition: Any steroid that acts as hormone.
has_obo_namespace: chebi_ontology
has_related_synonym: Steroidhormon
has_related_synonym: Steroidhormone
has_related_synonym: hormona esteroide
has_related_synonym: hormonas esteroideas
has_related_synonym: hormone steroide
has_related_synonym: hormones steroides
has_related_synonym: steroid hormones
id: CHEBI:26764
in_subset: 3 STAR

Axiom
annotated source: steroid hormone
annotated property: has_related_synonym
annotated target: Steroidhormon
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: has_related_synonym
annotated target: Steroidhormone
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: has_related_synonym
annotated target: hormona esteroide
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: has_related_synonym
annotated target: hormonas esteroideas
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: has_related_synonym
annotated target: hormone steroide
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: has_related_synonym
annotated target: hormones steroides
database_cross_reference: ChEBI

Axiom
annotated source: steroid hormone
annotated property: has_related_synonym
annotated target: steroid hormones
database_cross_reference: ChEBI

carbohydrate phosphate
type: Class
subclass of: organic phosphate
subclass of: phosphoric ester
subclass of: carbohydrate derivative

sulfuric ester
type: Class
subclass of: ester
subclass of: sulfuric acid derivative
definition: An ester of an alcohol and sulfuric acid.
charge: 0
formula: O4SR2
mass: 96.06300
monoisotopicmass: 95.95173
smiles: [*]OS(=O)(=O)O[*]
has_obo_namespace: chebi_ontology
has_related_synonym: sulfate ester
has_related_synonym: sulfuric acid ester
has_related_synonym: sulfuric acid esters
id: CHEBI:26819
in_subset: 3 STAR

Axiom
annotated source: sulfuric ester
annotated property: has_related_synonym
annotated target: sulfate ester
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric ester
annotated property: has_related_synonym
annotated target: sulfuric acid ester
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric ester
annotated property: has_related_synonym
annotated target: sulfuric acid esters
database_cross_reference: ChEBI

sulfates
type: Class
subclass of: sulfuric acid derivative
definition: Salts and esters of sulfuric acid
has_exact_synonym: sulfates
has_obo_namespace: chebi_ontology
has_related_synonym: sulfuric acid derivative
has_related_synonym: sulphates
id: CHEBI:26820
in_subset: 3 STAR

Axiom
annotated source: sulfates
annotated property: has_exact_synonym
annotated target: sulfates
database_cross_reference: ChEBI

Axiom
annotated source: sulfates
annotated property: has_related_synonym
annotated target: sulfuric acid derivative
database_cross_reference: ChEBI

Axiom
annotated source: sulfates
annotated property: has_related_synonym
annotated target: sulphates
database_cross_reference: ChEBI

sulfide
type: Class
subclass of: sulfur molecular entity

sulfur atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: S
inchi: InChI=1S/S
inchikey: NINIDFKCEFEMDL-UHFFFAOYSA-N
mass: 32.06600
monoisotopicmass: 31.97207
smiles: [S]
database_cross_reference: CAS:7704-34-9
database_cross_reference: KEGG:C00087
database_cross_reference: KEGG:D06527
database_cross_reference: PPDB:605
database_cross_reference: WebElements:S
has_exact_synonym: sulfur
has_obo_namespace: chebi_ontology
has_related_synonym: 16S
has_related_synonym: Elemental sulfur
has_related_synonym: S
has_related_synonym: Schwefel
has_related_synonym: azufre
has_related_synonym: soufre
has_related_synonym: sulfur
has_related_synonym: sulphur
has_related_synonym: theion
id: CHEBI:26833
in_subset: 3 STAR

Axiom
annotated source: sulfur atom
annotated property: database_cross_reference
annotated target: CAS:7704-34-9
source: ChemIDplus

Axiom
annotated source: sulfur atom
annotated property: database_cross_reference
annotated target: CAS:7704-34-9
source: NIST Chemistry WebBook

Axiom
annotated source: sulfur atom
annotated property: has_exact_synonym
annotated target: sulfur
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: 16S
database_cross_reference: IUPAC

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: Elemental sulfur
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: S
database_cross_reference: IUPAC

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: S
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: Schwefel
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: azufre
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: soufre
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: sulfur
database_cross_reference: UniProt

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: sulphur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur atom
annotated property: has_related_synonym
annotated target: theion
database_cross_reference: IUPAC

sulfur molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: sulfur atom
has_exact_synonym: sulfur molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: sulfur molecular entities
id: CHEBI:26835
in_subset: 3 STAR

Axiom
annotated source: sulfur molecular entity
annotated property: has_exact_synonym
annotated target: sulfur molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: sulfur molecular entity
annotated property: has_related_synonym
annotated target: sulfur molecular entities
database_cross_reference: ChEBI

sulfuric acid
type: Class
subclass of: sulfur oxoacid
subclass of: Restriction
  on property: has role
  some values from: catalyst
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogensulfate
definition: A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom.
charge: 0
formula: H2O4S
inchi: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)
inchikey: QAOWNCQODCNURD-UHFFFAOYSA-N
mass: 98.07948
monoisotopicmass: 97.96738
smiles: [H]OS(=O)(=O)O[H]
database_cross_reference: CAS:7664-93-9
database_cross_reference: Gmelin:2122
database_cross_reference: KEGG:C00059
database_cross_reference: KEGG:D05963
database_cross_reference: KNApSAcK:C00007530
database_cross_reference: MolBase:4
database_cross_reference: PMID:13568755
database_cross_reference: PMID:16122922
database_cross_reference: PMID:19397353
database_cross_reference: PMID:22047659
database_cross_reference: PMID:22136045
database_cross_reference: PMID:22204399
database_cross_reference: PMID:22267186
database_cross_reference: PMID:22296037
database_cross_reference: PMID:22364556
database_cross_reference: PMID:22435616
database_cross_reference: PPDB:606
database_cross_reference: Reaxys:2037554
database_cross_reference: Wikipedia:Sulfuric_acid
has_exact_synonym: Sulfuric acid
has_exact_synonym: dihydrogen tetraoxosulfate
has_exact_synonym: dihydroxidodioxidosulfur
has_exact_synonym: hydrogen tetraoxosulfate(2-)
has_exact_synonym: hydrogen tetraoxosulfate(VI)
has_exact_synonym: sulfuric acid
has_exact_synonym: tetraoxosulfuric acid
has_obo_namespace: chebi_ontology
has_related_synonym: Acide sulfurique
has_related_synonym: Acido sulfurico
has_related_synonym: Acidum sulfuricum
has_related_synonym: H2SO4
has_related_synonym: Schwefelsaeureloesungen
has_related_synonym: [S(OH)2O2]
has_related_synonym: [SO2(OH)2]
has_related_synonym: sulphuric acid
id: CHEBI:26836
in_subset: 3 STAR

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: CAS:7664-93-9
source: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: CAS:7664-93-9
source: KEGG COMPOUND

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: CAS:7664-93-9
source: NIST Chemistry WebBook

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: Gmelin:2122
source: Gmelin

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:13568755
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:16122922
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:19397353
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22047659
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22136045
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22204399
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22267186
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22296037
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22364556
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: PMID:22435616
source: Europe PMC

Axiom
annotated source: sulfuric acid
annotated property: database_cross_reference
annotated target: Reaxys:2037554
source: Reaxys

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: Sulfuric acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: dihydrogen tetraoxosulfate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: dihydroxidodioxidosulfur
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: hydrogen tetraoxosulfate(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: hydrogen tetraoxosulfate(VI)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: sulfuric acid
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: sulfuric acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_exact_synonym
annotated target: tetraoxosulfuric acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: Acide sulfurique
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: Acido sulfurico
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: Acidum sulfuricum
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: H2SO4
database_cross_reference: IUPAC

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: Schwefelsaeureloesungen
database_cross_reference: ChemIDplus

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: [S(OH)2O2]
database_cross_reference: MolBase

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: [SO2(OH)2]
database_cross_reference: IUPAC

Axiom
annotated source: sulfuric acid
annotated property: has_related_synonym
annotated target: sulphuric acid
database_cross_reference: MolBase

terpenoid
type: Class
subclass of: isoprenoid

tertiary alcohol
type: Class
subclass of: alcohol

tetrapyrrole
type: Class
subclass of: heteroarene
subclass of: polypyrrole
definition: A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
has_exact_synonym: tetrapyrrole
has_exact_synonym: tetrapyrroles
has_obo_namespace: chebi_ontology
has_related_synonym: a tetrapyrrole
id: CHEBI:26932
in_subset: 3 STAR

Axiom
annotated source: tetrapyrrole
annotated property: has_exact_synonym
annotated target: tetrapyrrole
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: tetrapyrrole
annotated property: has_exact_synonym
annotated target: tetrapyrroles
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: tetrapyrrole
annotated property: has_related_synonym
annotated target: a tetrapyrrole
database_cross_reference: UniProt

tetraterpenoid
type: Class
subclass of: terpenoid

organic heterotricyclic compound
type: Class
subclass of: heterotricyclic compound
subclass of: organic heteropolycyclic compound
subclass of: organic tricyclic compound

threonine
type: Class
subclass of: polar amino acid
subclass of: 2-amino-3-hydroxybutanoic acid

tin atom
type: Class
subclass of: carbon group element atom
subclass of: metal atom

toluenes
type: Class
subclass of: benzenes

toxin
type: Class
subclass of: metabolite
subclass of: poison

micronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
database_cross_reference: Wikipedia:Micronutrient
has_obo_namespace: chebi_ontology
has_related_synonym: micronutrients
has_related_synonym: trace elements
id: CHEBI:27027
in_subset: 3 STAR

Axiom
annotated source: micronutrient
annotated property: has_related_synonym
annotated target: micronutrients
database_cross_reference: ChEBI

Axiom
annotated source: micronutrient
annotated property: has_related_synonym
annotated target: trace elements
database_cross_reference: ChEBI

Anatoxin a
type: Class
subclass of: tropane alkaloid

transition element atom
type: Class
subclass of: metal atom
definition: An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell.
has_exact_synonym: transition element
has_related_synonym: Uebergangselement
has_related_synonym: Uebergangsmetalle
has_related_synonym: metal de transicion
has_related_synonym: metal de transition
has_related_synonym: metales de transicion
has_related_synonym: metaux de transition
has_related_synonym: transition element
has_related_synonym: transition elements
has_related_synonym: transition metal
has_related_synonym: transition metals

monoatomic trication
type: Class
subclass of: monoatomic polycation
subclass of: trivalent inorganic cation

tryptamines
type: Class
subclass of: indoles
definition: Tryptamine and its substitution derivatives.
has_obo_namespace: chebi_ontology
id: CHEBI:27162
in_subset: 3 STAR

organic heterobicyclic compound
type: Class
subclass of: heterobicyclic compound
subclass of: organic heteropolycyclic compound
has_obo_namespace: chebi_ontology
has_related_synonym: heterobicyclic compounds
has_related_synonym: organic heterobicyclic compounds
id: CHEBI:27171
in_subset: 3 STAR

Axiom
annotated source: organic heterobicyclic compound
annotated property: has_related_synonym
annotated target: heterobicyclic compounds
database_cross_reference: ChEBI

Axiom
annotated source: organic heterobicyclic compound
annotated property: has_related_synonym
annotated target: organic heterobicyclic compounds
database_cross_reference: ChEBI

univalent carboacyl group
type: Class
subclass of: carboacyl group
definition: A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.
has_obo_namespace: chebi_ontology
has_related_synonym: univalent acyl group
has_related_synonym: univalent carboacyl groups
has_related_synonym: univalent carboxylic acyl groups
id: CHEBI:27207
in_subset: 3 STAR

Axiom
annotated source: univalent carboacyl group
annotated property: has_related_synonym
annotated target: univalent acyl group
database_cross_reference: ChEBI

Axiom
annotated source: univalent carboacyl group
annotated property: has_related_synonym
annotated target: univalent carboacyl groups
database_cross_reference: ChEBI

Axiom
annotated source: univalent carboacyl group
annotated property: has_related_synonym
annotated target: univalent carboxylic acyl groups
database_cross_reference: ChEBI

vanadium molecular entity
type: Class
subclass of: vanadium group molecular entity

very long-chain fatty acid
type: Class
subclass of: fatty acid

violaxanthin
type: Class
subclass of: epoxycarotenol

xanthophyll
type: Class
subclass of: carotenoid

xylene
type: Class
subclass of: volatile organic compound
subclass of: methylbenzene

zinc atom
type: Class
subclass of: zinc group element atom

zinc molecular entity
type: Class
subclass of: zinc group molecular entity

zwitterion
type: Class
subclass of: dipolar compound
definition: A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).
has_exact_synonym: zwitterion
has_exact_synonym: zwitterions
has_obo_namespace: chebi_ontology
has_related_synonym: compose zwitterionique
has_related_synonym: compuestos zwitterionicos
has_related_synonym: zwitteriones
has_related_synonym: zwitterionic compounds
id: CHEBI:27369
in_subset: 3 STAR

Axiom
annotated source: zwitterion
annotated property: has_exact_synonym
annotated target: zwitterion
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: zwitterion
annotated property: has_exact_synonym
annotated target: zwitterions
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: zwitterion
annotated property: has_related_synonym
annotated target: compose zwitterionique
database_cross_reference: IUPAC

Axiom
annotated source: zwitterion
annotated property: has_related_synonym
annotated target: compuestos zwitterionicos
database_cross_reference: IUPAC

Axiom
annotated source: zwitterion
annotated property: has_related_synonym
annotated target: zwitteriones
database_cross_reference: IUPAC

Axiom
annotated source: zwitterion
annotated property: has_related_synonym
annotated target: zwitterionic compounds
database_cross_reference: IUPAC

methanesulfonic acid
type: Class
subclass of: alkanesulfonic acid
subclass of: one-carbon compound

zeaxanthin
type: Class
subclass of: carotenol

boron atom
type: Class
subclass of: metalloid atom
subclass of: nonmetal atom
subclass of: boron group element atom

arsenic atom
type: Class
subclass of: metalloid atom
subclass of: pnictogen

silicon atom
type: Class
subclass of: metalloid atom
subclass of: nonmetal atom
subclass of: carbon group element atom

carbon atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: carbon group element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: C
inchi: InChI=1S/C
inchikey: OKTJSMMVPCPJKN-UHFFFAOYSA-N
mass: 12.01070
monoisotopicmass: 12.00000
smiles: [C]
has_alternative_id: CHEBI:23009
has_alternative_id: CHEBI:3399
database_cross_reference: CAS:7440-44-0
database_cross_reference: KEGG:C06265
database_cross_reference: WebElements:C
has_exact_synonym: carbon
has_obo_namespace: chebi_ontology
has_related_synonym: 6C
has_related_synonym: C
has_related_synonym: Carbon
has_related_synonym: Kohlenstoff
has_related_synonym: carbon
has_related_synonym: carbone
has_related_synonym: carbonium
has_related_synonym: carbono
id: CHEBI:27594
in_subset: 3 STAR

Axiom
annotated source: carbon atom
annotated property: database_cross_reference
annotated target: CAS:7440-44-0
source: ChemIDplus

Axiom
annotated source: carbon atom
annotated property: database_cross_reference
annotated target: CAS:7440-44-0
source: KEGG COMPOUND

Axiom
annotated source: carbon atom
annotated property: has_exact_synonym
annotated target: carbon
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: 6C
database_cross_reference: IUPAC

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: C
database_cross_reference: IUPAC

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: C
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: Carbon
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: Kohlenstoff
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: carbon
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: carbone
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: carbonium
database_cross_reference: ChEBI

Axiom
annotated source: carbon atom
annotated property: has_related_synonym
annotated target: carbono
database_cross_reference: ChEBI

cobalt atom
type: Class
subclass of: cobalt group element atom
subclass of: metal allergen

detergent
type: Class
subclass of: application
subclass of: surfactant

nitrobenzene
type: Class
subclass of: nitrobenzenes
subclass of: nitroarene

acetamide
type: Class
subclass of: acetamides
subclass of: monocarboxylic acid amide
subclass of: N-acylammonia

chlorophyll b
type: Class
subclass of: chlorophyll

lead(0)
type: Class
subclass of: elemental lead

chromium atom
type: Class
subclass of: chromium group element atom
subclass of: metal allergen

glycogen
type: Class
subclass of: independent continuant
subclass of: glycogens
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
definition: A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.
has_alternative_id: CHEBI:24379
has_alternative_id: CHEBI:5466
database_cross_reference: CAS:9005-79-2
database_cross_reference: GlyGen:G99991IU
database_cross_reference: GlyTouCan:G99991IU
database_cross_reference: HMDB:HMDB0000757
database_cross_reference: KEGG:C00182
database_cross_reference: MetaCyc:CPD0-971
database_cross_reference: Wikipedia:Glycogen
has_exact_synonym: Glycogen
has_obo_namespace: chebi_ontology
has_related_synonym: WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1
has_related_synonym: animal starch
has_related_synonym: liver starch
id: CHEBI:28087
in_subset: 3 STAR

Axiom
annotated source: glycogen
annotated property: database_cross_reference
annotated target: CAS:9005-79-2
source: ChemIDplus

Axiom
annotated source: glycogen
annotated property: database_cross_reference
annotated target: CAS:9005-79-2
source: KEGG COMPOUND

Axiom
annotated source: glycogen
annotated property: has_exact_synonym
annotated target: Glycogen
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glycogen
annotated property: has_related_synonym
annotated target: WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1
database_cross_reference: GlyTouCan

Axiom
annotated source: glycogen
annotated property: has_related_synonym
annotated target: animal starch
database_cross_reference: ChemIDplus

Axiom
annotated source: glycogen
annotated property: has_related_synonym
annotated target: liver starch
database_cross_reference: ChemIDplus

nickel atom
type: Class
subclass of: nickel group element atom
subclass of: metal allergen

alloxanthine
type: Class
subclass of: pyrazolopyrimidine

alpha-carotene
type: Class
subclass of: carotenoid beta-end derivative
subclass of: cyclic carotene

carbamic acid
type: Class
subclass of: organonitrogen compound
subclass of: carbon oxoacid
subclass of: one-carbon compound
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbamate
definition: A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.
charge: 0
formula: CH3NO2
inchi: InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)
inchikey: KXDHJXZQYSOELW-UHFFFAOYSA-N
mass: 61.04006
monoisotopicmass: 61.01638
smiles: NC(O)=O
has_alternative_id: CHEBI:22504
has_alternative_id: CHEBI:23002
has_alternative_id: CHEBI:3386
has_alternative_id: CHEBI:44573
database_cross_reference: Beilstein:1734754
database_cross_reference: CAS:463-77-4
database_cross_reference: DrugBank:DB04261
database_cross_reference: Gmelin:130345
database_cross_reference: KEGG:C01563
database_cross_reference: PDBeChem:OUT
database_cross_reference: Wikipedia:Carbamic_acid
has_exact_synonym: CARBAMIC ACID
has_exact_synonym: Carbamic acid
has_exact_synonym: carbamic acid
has_obo_namespace: chebi_ontology
has_related_synonym: Aminoameisensaeure
has_related_synonym: Aminoformic acid
has_related_synonym: Carbamate
has_related_synonym: Carbamidsaeure
id: CHEBI:28616
in_subset: 3 STAR

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: Beilstein:1734754
source: Beilstein

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: CAS:463-77-4
source: ChemIDplus

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: CAS:463-77-4
source: KEGG COMPOUND

Axiom
annotated source: carbamic acid
annotated property: database_cross_reference
annotated target: Gmelin:130345
source: Gmelin

Axiom
annotated source: carbamic acid
annotated property: has_exact_synonym
annotated target: CARBAMIC ACID
database_cross_reference: PDBeChem

Axiom
annotated source: carbamic acid
annotated property: has_exact_synonym
annotated target: Carbamic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbamic acid
annotated property: has_exact_synonym
annotated target: carbamic acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbamic acid
annotated property: has_related_synonym
annotated target: Aminoameisensaeure
database_cross_reference: ChEBI

Axiom
annotated source: carbamic acid
annotated property: has_related_synonym
annotated target: Aminoformic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbamic acid
annotated property: has_related_synonym
annotated target: Carbamate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbamic acid
annotated property: has_related_synonym
annotated target: Carbamidsaeure
database_cross_reference: ChEBI

phosphorus atom
type: Class
subclass of: independent continuant
subclass of: nonmetal atom
subclass of: pnictogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: P
inchi: InChI=1S/P
inchikey: OAICVXFJPJFONN-UHFFFAOYSA-N
mass: 30.97376
monoisotopicmass: 30.97376
smiles: [P]
has_alternative_id: CHEBI:26080
has_alternative_id: CHEBI:8168
database_cross_reference: CAS:7723-14-0
database_cross_reference: Gmelin:16235
database_cross_reference: KEGG:C06262
database_cross_reference: WebElements:P
has_exact_synonym: phosphorus
has_obo_namespace: chebi_ontology
has_related_synonym: 15P
has_related_synonym: P
has_related_synonym: Phosphor
has_related_synonym: Phosphorus
has_related_synonym: fosforo
has_related_synonym: phosphore
has_related_synonym: phosphorus
id: CHEBI:28659
in_subset: 3 STAR

Axiom
annotated source: phosphorus atom
annotated property: database_cross_reference
annotated target: CAS:7723-14-0
source: ChemIDplus

Axiom
annotated source: phosphorus atom
annotated property: database_cross_reference
annotated target: CAS:7723-14-0
source: KEGG COMPOUND

Axiom
annotated source: phosphorus atom
annotated property: database_cross_reference
annotated target: Gmelin:16235
source: Gmelin

Axiom
annotated source: phosphorus atom
annotated property: has_exact_synonym
annotated target: phosphorus
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: 15P
database_cross_reference: IUPAC

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: P
database_cross_reference: IUPAC

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: P
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: Phosphor
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: Phosphorus
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: fosforo
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: phosphore
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus atom
annotated property: has_related_synonym
annotated target: phosphorus
database_cross_reference: ChEBI

molybdenum atom
type: Class
subclass of: chromium group element atom

copper atom
type: Class
subclass of: copper group element atom
subclass of: metal allergen

serotonin
type: Class
subclass of: monoamine molecular messenger
subclass of: tryptamines
subclass of: phenols
subclass of: primary amino compound
subclass of: hydroxyindoles
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: has functional parent
  some values from: tryptamine
subclass of: Restriction
  on property: is conjugate base of
  some values from: serotonin(1+)
definition: A primary amino compound that is the 5-hydroxy derivative of tryptamine.
charge: 0
formula: C10H12N2O
inchi: InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
inchikey: QZAYGJVTTNCVMB-UHFFFAOYSA-N
mass: 176.215
monoisotopicmass: 176.09496
smiles: C1=CC(=CC=2C(=CNC12)CCN)O
has_alternative_id: CHEBI:1420
has_alternative_id: CHEBI:26652
has_alternative_id: CHEBI:49894
database_cross_reference: Beilstein:143524
database_cross_reference: CAS:50-67-9
database_cross_reference: Gmelin:1861995
database_cross_reference: HMDB:HMDB0000259
database_cross_reference: KEGG:C00780
database_cross_reference: KNApSAcK:C00001429
database_cross_reference: LINCS:LSM-6589
database_cross_reference: MetaCyc:SEROTONIN
database_cross_reference: PDBeChem:SRO
database_cross_reference: PMID:18593914
database_cross_reference: PMID:22770225
database_cross_reference: PMID:24136337
database_cross_reference: Reaxys:143524
database_cross_reference: Wikipedia:Serotonin
has_exact_synonym: 3-(2-aminoethyl)-1H-indol-5-ol
has_exact_synonym: SEROTONIN
has_exact_synonym: Serotonin
has_obo_namespace: chebi_ontology
has_related_synonym: 3-(2-Aminoethyl)-1H-indol-5-ol
has_related_synonym: 5-HT
has_related_synonym: 5-Hydroxytryptamine
has_related_synonym: Enteramine
has_related_synonym: serotonine
has_related_synonym: thrombocytin
has_related_synonym: thrombotonin
id: CHEBI:28790
in_subset: 3 STAR

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: Beilstein:143524
source: Beilstein

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: CAS:50-67-9
source: ChemIDplus

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: CAS:50-67-9
source: KEGG COMPOUND

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: Gmelin:1861995
source: Gmelin

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: PMID:18593914
source: Europe PMC

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: PMID:22770225
source: Europe PMC

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: PMID:24136337
source: Europe PMC

Axiom
annotated source: serotonin
annotated property: database_cross_reference
annotated target: Reaxys:143524
source: Reaxys

Axiom
annotated source: serotonin
annotated property: has_exact_synonym
annotated target: 3-(2-aminoethyl)-1H-indol-5-ol
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: serotonin
annotated property: has_exact_synonym
annotated target: SEROTONIN
database_cross_reference: PDBeChem

Axiom
annotated source: serotonin
annotated property: has_exact_synonym
annotated target: Serotonin
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: has_related_synonym
annotated target: 3-(2-Aminoethyl)-1H-indol-5-ol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: has_related_synonym
annotated target: 5-HT
database_cross_reference: IUPHAR

Axiom
annotated source: serotonin
annotated property: has_related_synonym
annotated target: 5-Hydroxytryptamine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: has_related_synonym
annotated target: Enteramine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: serotonin
annotated property: has_related_synonym
annotated target: serotonine
database_cross_reference: ChEBI

Axiom
annotated source: serotonin
annotated property: has_related_synonym
annotated target: thrombocytin
database_cross_reference: ChemIDplus

Axiom
annotated source: serotonin
annotated property: has_related_synonym
annotated target: thrombotonin
database_cross_reference: ChemIDplus

beta-D-glucan
type: Class
subclass of: glucan

rubber particle
type: Class
subclass of: polymer

lutein
type: Class
subclass of: carotenol

fatty acid anion
type: Class
subclass of: lipid
subclass of: monocarboxylic acid anion

ammonium
type: Class
subclass of: independent continuant
subclass of: nitrogen hydride
subclass of: onium cation
subclass of: monovalent inorganic cation
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: Escherichia coli metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: ammonia
definition: An onium cation obtained by protonation of ammonia.
charge: +1
formula: H4N
inchi: InChI=1S/H3N/h1H3/p+1
inchikey: QGZKDVFQNNGYKY-UHFFFAOYSA-O
mass: 18.03850
monoisotopicmass: 18.03383
smiles: [H][N+]([H])([H])[H]
has_alternative_id: CHEBI:22534
has_alternative_id: CHEBI:49783
has_alternative_id: CHEBI:7435
database_cross_reference: CAS:14798-03-9
database_cross_reference: Gmelin:84
database_cross_reference: KEGG:C01342
database_cross_reference: MetaCyc:AMMONIUM
database_cross_reference: MolBase:929
database_cross_reference: PDBeChem:NH4
database_cross_reference: PMID:11319011
database_cross_reference: PMID:11341317
database_cross_reference: PMID:12096804
database_cross_reference: PMID:14512268
database_cross_reference: PMID:14879753
database_cross_reference: PMID:16345391
database_cross_reference: PMID:16903292
database_cross_reference: PMID:17392693
database_cross_reference: PMID:18515490
database_cross_reference: PMID:19199063
database_cross_reference: PMID:19596600
database_cross_reference: PMID:19682559
database_cross_reference: PMID:19716251
database_cross_reference: PMID:21993530
database_cross_reference: PMID:22265469
database_cross_reference: PMID:22524020
database_cross_reference: PMID:22562341
database_cross_reference: PMID:22631217
database_cross_reference: Reaxys:16093784
database_cross_reference: Wikipedia:Ammonium
has_exact_synonym: ammonium
has_exact_synonym: azanium
has_obo_namespace: chebi_ontology
has_related_synonym: Ammonium(1+)
has_related_synonym: NH4(+)
has_related_synonym: NH4+
has_related_synonym: [NH4](+)
has_related_synonym: ammonium cation
has_related_synonym: ammonium ion
id: CHEBI:28938
in_subset: 3 STAR

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: CAS:14798-03-9
source: ChemIDplus

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: CAS:14798-03-9
source: NIST Chemistry WebBook

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: Gmelin:84
source: Gmelin

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:11319011
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:11341317
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:12096804
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:14512268
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:14879753
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:16345391
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:16903292
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:17392693
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:18515490
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19199063
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19596600
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19682559
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:19716251
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:21993530
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22265469
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22524020
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22562341
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: PMID:22631217
source: Europe PMC

Axiom
annotated source: ammonium
annotated property: database_cross_reference
annotated target: Reaxys:16093784
source: Reaxys

Axiom
annotated source: ammonium
annotated property: has_exact_synonym
annotated target: ammonium
database_cross_reference: ChEBI

Axiom
annotated source: ammonium
annotated property: has_exact_synonym
annotated target: ammonium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: ammonium
annotated property: has_exact_synonym
annotated target: azanium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: ammonium
annotated property: has_related_synonym
annotated target: Ammonium(1+)
database_cross_reference: ChemIDplus

Axiom
annotated source: ammonium
annotated property: has_related_synonym
annotated target: NH4(+)
database_cross_reference: IUPAC

Axiom
annotated source: ammonium
annotated property: has_related_synonym
annotated target: NH4(+)
database_cross_reference: UniProt

Axiom
annotated source: ammonium
annotated property: has_related_synonym
annotated target: NH4+
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ammonium
annotated property: has_related_synonym
annotated target: [NH4](+)
database_cross_reference: MolBase

Axiom
annotated source: ammonium
annotated property: has_related_synonym
annotated target: ammonium cation
database_cross_reference: ChemIDplus

Axiom
annotated source: ammonium
annotated property: has_related_synonym
annotated target: ammonium ion
database_cross_reference: PDBeChem

amino sugar
type: Class
subclass of: carbohydrate derivative

dicarboxylic acid dianion
type: Class
subclass of: dicarboxylic acid anion
subclass of: carboxylic acid dianion
definition: A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid.
charge: -2
formula: C2O4R
mass: 88.019
monoisotopicmass: 87.97966
smiles: [O-]C(=O)[*]C([O-])=O
has_alternative_id: CHEBI:13632
has_alternative_id: CHEBI:23688
has_alternative_id: CHEBI:23689
has_alternative_id: CHEBI:38711
has_exact_synonym: dicarboxylic acid dianion
has_obo_namespace: chebi_ontology
has_related_synonym: a dicarboxylate
has_related_synonym: dicarboxylate
has_related_synonym: dicarboxylates
has_related_synonym: dicarboxylic acid dianions
id: CHEBI:28965
in_subset: 3 STAR

Axiom
annotated source: dicarboxylic acid dianion
annotated property: has_exact_synonym
annotated target: dicarboxylic acid dianion
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid dianion
annotated property: has_related_synonym
annotated target: a dicarboxylate
database_cross_reference: UniProt

Axiom
annotated source: dicarboxylic acid dianion
annotated property: has_related_synonym
annotated target: dicarboxylate
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid dianion
annotated property: has_related_synonym
annotated target: dicarboxylates
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid dianion
annotated property: has_related_synonym
annotated target: dicarboxylic acid dianions
database_cross_reference: ChEBI

chlorophyll
type: Class
subclass of: magnesium porphyrin

carbonic acid
type: Class
subclass of: carbon oxoacid
subclass of: chalcocarbonic acid
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogencarbonate
charge: 0
formula: CH2O3
inchi: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)
inchikey: BVKZGUZCCUSVTD-UHFFFAOYSA-N
mass: 62.02478
monoisotopicmass: 62.00039
smiles: OC(O)=O
has_alternative_id: CHEBI:13351
has_alternative_id: CHEBI:23017
has_alternative_id: CHEBI:23744
has_alternative_id: CHEBI:3401
database_cross_reference: CAS:463-79-6
database_cross_reference: Gmelin:25554
database_cross_reference: KEGG:C01353
database_cross_reference: PDBeChem:CO3
has_exact_synonym: Carbonic acid
has_exact_synonym: carbonic acid
has_exact_synonym: dihydroxidooxidocarbon
has_obo_namespace: chebi_ontology
has_related_synonym: Dihydrogen carbonate
has_related_synonym: H2CO3
has_related_synonym: Koehlensaeure
has_related_synonym: [CO(OH)2]
id: CHEBI:28976
in_subset: 3 STAR

Axiom
annotated source: carbonic acid
annotated property: database_cross_reference
annotated target: CAS:463-79-6
source: ChemIDplus

Axiom
annotated source: carbonic acid
annotated property: database_cross_reference
annotated target: CAS:463-79-6
source: KEGG COMPOUND

Axiom
annotated source: carbonic acid
annotated property: database_cross_reference
annotated target: Gmelin:25554
source: Gmelin

Axiom
annotated source: carbonic acid
annotated property: has_exact_synonym
annotated target: Carbonic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbonic acid
annotated property: has_exact_synonym
annotated target: carbonic acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbonic acid
annotated property: has_exact_synonym
annotated target: dihydroxidooxidocarbon
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbonic acid
annotated property: has_related_synonym
annotated target: Dihydrogen carbonate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbonic acid
annotated property: has_related_synonym
annotated target: H2CO3
database_cross_reference: IUPAC

Axiom
annotated source: carbonic acid
annotated property: has_related_synonym
annotated target: H2CO3
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carbonic acid
annotated property: has_related_synonym
annotated target: Koehlensaeure
database_cross_reference: ChEBI

Axiom
annotated source: carbonic acid
annotated property: has_related_synonym
annotated target: [CO(OH)2]
database_cross_reference: IUPAC

carboxylic acid anion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carboxylic acid
definition: The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
charge: -1
formula: CO2R
mass: 44.00950
monoisotopicmass: 43.98983
smiles: [O-]C([*])=O
has_alternative_id: CHEBI:13626
has_alternative_id: CHEBI:13945
has_alternative_id: CHEBI:23026
has_alternative_id: CHEBI:58657
has_obo_namespace: chebi_ontology
has_related_synonym: a carboxylate
has_related_synonym: carboxylic acid anions
has_related_synonym: carboxylic anions
id: CHEBI:29067
in_subset: 3 STAR

Axiom
annotated source: carboxylic acid anion
annotated property: has_related_synonym
annotated target: a carboxylate
database_cross_reference: UniProt

Axiom
annotated source: carboxylic acid anion
annotated property: has_related_synonym
annotated target: carboxylic acid anions
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid anion
annotated property: has_related_synonym
annotated target: carboxylic anions
database_cross_reference: ChEBI

mononucleotide
type: Class
subclass of: nucleotide

sodium(1+)
type: Class
subclass of: independent continuant
subclass of: monoatomic monocation
subclass of: alkali metal cation
subclass of: elemental sodium
subclass of: monovalent inorganic cation
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: human metabolite
definition: A monoatomic monocation obtained from sodium.
charge: +1
formula: Na
inchi: InChI=1S/Na/q+1
inchikey: FKNQFGJONOIPTF-UHFFFAOYSA-N
mass: 22.98977
monoisotopicmass: 22.98922
smiles: [Na+]
has_alternative_id: CHEBI:26717
has_alternative_id: CHEBI:49766
has_alternative_id: CHEBI:9175
database_cross_reference: CAS:17341-25-2
database_cross_reference: Gmelin:15196
database_cross_reference: KEGG:C01330
database_cross_reference: PDBeChem:NA
has_exact_synonym: sodium cation
has_exact_synonym: sodium(1+)
has_exact_synonym: sodium(1+) ion
has_exact_synonym: sodium(I) cation
has_obo_namespace: chebi_ontology
has_related_synonym: Na(+)
has_related_synonym: Na+
has_related_synonym: SODIUM ION
id: CHEBI:29101
in_subset: 3 STAR

Axiom
annotated source: sodium(1+)
annotated property: database_cross_reference
annotated target: CAS:17341-25-2
source: ChemIDplus

Axiom
annotated source: sodium(1+)
annotated property: database_cross_reference
annotated target: CAS:17341-25-2
source: NIST Chemistry WebBook

Axiom
annotated source: sodium(1+)
annotated property: database_cross_reference
annotated target: Gmelin:15196
source: Gmelin

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium cation
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium(1+)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium(1+) ion
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: has_exact_synonym
annotated target: sodium(I) cation
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: sodium(1+)
annotated property: has_related_synonym
annotated target: Na(+)
database_cross_reference: IUPAC

Axiom
annotated source: sodium(1+)
annotated property: has_related_synonym
annotated target: Na(+)
database_cross_reference: UniProt

Axiom
annotated source: sodium(1+)
annotated property: has_related_synonym
annotated target: Na+
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: sodium(1+)
annotated property: has_related_synonym
annotated target: SODIUM ION
database_cross_reference: PDBeChem

arsenate(3-)
type: Class
subclass of: arsenate ion

hydrogen fluoride
type: Class
subclass of: hydrogen halide
subclass of: mononuclear parent hydride

deuteron
type: Class
subclass of: hydron

deuterium atom
type: Class
subclass of: hydrogen atom

tritium atom
type: Class
subclass of: hydrogen atom

silicate(4-)
type: Class
subclass of: silicate ion

azanide
type: Class
subclass of: nitrogen hydride
subclass of: monovalent inorganic anion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydridonitrate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: ammonia
charge: -1
formula: H2N
inchi: InChI=1S/H2N/h1H2/q-1
inchikey: HYGWNUKOUCZBND-UHFFFAOYSA-N
mass: 16.02262
monoisotopicmass: 16.01927
smiles: [H][N-][H]
has_exact_synonym: amide
has_exact_synonym: azanide
has_exact_synonym: dihydridonitrate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: NH2(-)
id: CHEBI:29337
in_subset: 3 STAR

Axiom
annotated source: azanide
annotated property: has_exact_synonym
annotated target: amide
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: azanide
annotated property: has_exact_synonym
annotated target: azanide
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: azanide
annotated property: has_exact_synonym
annotated target: dihydridonitrate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: azanide
annotated property: has_related_synonym
annotated target: NH2(-)
database_cross_reference: IUPAC

hydridonitrate(2-)
type: Class
subclass of: nitrogen hydride
subclass of: divalent inorganic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: azanide
definition: A divalent inorganic anion resulting from the removal of two protons from ammonia.
charge: -2
formula: HN
inchi: InChI=1S/HN/h1H/q-2
inchikey: DZQYTNGKSBCIOE-UHFFFAOYSA-N
mass: 15.01468
monoisotopicmass: 15.01200
smiles: [N--][H]
has_exact_synonym: azanediide
has_exact_synonym: hydridonitrate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: NH(2-)
has_related_synonym: imide
id: CHEBI:29340
in_subset: 3 STAR

Axiom
annotated source: hydridonitrate(2-)
annotated property: has_exact_synonym
annotated target: azanediide
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydridonitrate(2-)
annotated property: has_exact_synonym
annotated target: hydridonitrate(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydridonitrate(2-)
annotated property: has_related_synonym
annotated target: NH(2-)
database_cross_reference: IUPAC

Axiom
annotated source: hydridonitrate(2-)
annotated property: has_related_synonym
annotated target: imide
database_cross_reference: IUPAC

monocarboxylic acid amide
type: Class
subclass of: carboxamide

oxonium
type: Class
subclass of: oxygen hydride
subclass of: onium cation

methanide
type: Class
subclass of: hydrocarbyl anion

hydridodioxygen(1+)
type: Class
subclass of: oxygen hydride
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dioxygen
charge: +1
formula: HO2
inchi: InChI=1S/O2/c1-2/p+1
inchikey: MYMOFIZGZYHOMD-UHFFFAOYSA-O
mass: 33.00674
monoisotopicmass: 32.99711
smiles: [H][O+]=O
database_cross_reference: Gmelin:508
has_exact_synonym: dioxidenium
has_exact_synonym: hydridodioxygen(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: HO2(+)
has_related_synonym: HOO(+)
has_related_synonym: [HO2](+)
id: CHEBI:29793
in_subset: 3 STAR

Axiom
annotated source: hydridodioxygen(1+)
annotated property: database_cross_reference
annotated target: Gmelin:508
source: Gmelin

Axiom
annotated source: hydridodioxygen(1+)
annotated property: has_exact_synonym
annotated target: dioxidenium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydridodioxygen(1+)
annotated property: has_exact_synonym
annotated target: hydridodioxygen(1+)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydridodioxygen(1+)
annotated property: has_related_synonym
annotated target: HO2(+)
database_cross_reference: IUPAC

Axiom
annotated source: hydridodioxygen(1+)
annotated property: has_related_synonym
annotated target: HOO(+)
database_cross_reference: ChEBI

Axiom
annotated source: hydridodioxygen(1+)
annotated property: has_related_synonym
annotated target: [HO2](+)
database_cross_reference: ChEBI

hydrosulfide
type: Class
subclass of: sulfur hydride

bacteriochlorophyll a
type: Class
subclass of: methyl ester
subclass of: bacteriochlorophyll

gold(0)
type: Class
subclass of: elemental gold

copper(0)
type: Class
subclass of: elemental copper

acetate
type: Class
subclass of: independent continuant
subclass of: monocarboxylic acid anion
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: acetic acid
definition: A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.
charge: -1
formula: C2H3O2
inchi: InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1
inchikey: QTBSBXVTEAMEQO-UHFFFAOYSA-M
mass: 59.04402
monoisotopicmass: 59.01385
smiles: CC([O-])=O
has_alternative_id: CHEBI:13704
has_alternative_id: CHEBI:22165
has_alternative_id: CHEBI:40480
database_cross_reference: Beilstein:1901470
database_cross_reference: CAS:71-50-1
database_cross_reference: DrugBank:DB03166
database_cross_reference: Gmelin:1379
database_cross_reference: KEGG:C00033
database_cross_reference: MetaCyc:ACET
database_cross_reference: PDBeChem:ACT
database_cross_reference: PMID:17190852
database_cross_reference: PMID:22211106
database_cross_reference: PMID:22371380
database_cross_reference: Reaxys:1901470
database_cross_reference: UM-BBD_compID:c0050
database_cross_reference: Wikipedia:Acetate
has_exact_synonym: acetate
has_obo_namespace: chebi_ontology
has_related_synonym: ACETATE ION
has_related_synonym: Azetat
has_related_synonym: CH3-COO(-)
has_related_synonym: Ethanoat
has_related_synonym: MeCO2 anion
has_related_synonym: acetic acid, ion(1-)
has_related_synonym: ethanoate
id: CHEBI:30089
in_subset: 3 STAR

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: Beilstein:1901470
source: Beilstein

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: CAS:71-50-1
source: ChemIDplus

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: CAS:71-50-1
source: NIST Chemistry WebBook

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: Gmelin:1379
source: Gmelin

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: PMID:17190852
source: Europe PMC

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: PMID:22211106
source: Europe PMC

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: PMID:22371380
source: Europe PMC

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: Reaxys:1901470
source: Reaxys

Axiom
annotated source: acetate
annotated property: database_cross_reference
annotated target: UM-BBD_compID:c0050
source: UM-BBD

Axiom
annotated source: acetate
annotated property: has_exact_synonym
annotated target: acetate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: acetate
annotated property: has_exact_synonym
annotated target: acetate
database_cross_reference: UniProt

Axiom
annotated source: acetate
annotated property: has_related_synonym
annotated target: ACETATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: acetate
annotated property: has_related_synonym
annotated target: Azetat
database_cross_reference: ChEBI

Axiom
annotated source: acetate
annotated property: has_related_synonym
annotated target: CH3-COO(-)
database_cross_reference: IUPAC

Axiom
annotated source: acetate
annotated property: has_related_synonym
annotated target: Ethanoat
database_cross_reference: ChEBI

Axiom
annotated source: acetate
annotated property: has_related_synonym
annotated target: MeCO2 anion
database_cross_reference: NIST_Chemistry_WebBook

Axiom
annotated source: acetate
annotated property: has_related_synonym
annotated target: acetic acid, ion(1-)
database_cross_reference: ChemIDplus

Axiom
annotated source: acetate
annotated property: has_related_synonym
annotated target: ethanoate
database_cross_reference: ChEBI

lithium atom
type: Class
subclass of: alkali metal atom

aluminium oxide
type: Class
subclass of: aluminium oxides

photon
type: Class
subclass of: boson
definition: Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force.
charge: 0
mass: 0.0
monoisotopicmass: 0.0
smiles: *
has_alternative_id: CHEBI:10581
has_alternative_id: CHEBI:14383
database_cross_reference: KEGG:C00205
has_exact_synonym: photon
has_obo_namespace: chebi_ontology
has_related_synonym: Lichtquant
has_related_synonym: Light
has_related_synonym: foton
has_related_synonym: gamma
has_related_synonym: hnu
has_related_synonym: light quantum
id: CHEBI:30212
in_subset: 3 STAR

Axiom
annotated source: photon
annotated property: has_exact_synonym
annotated target: photon
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: photon
annotated property: has_related_synonym
annotated target: Lichtquant
database_cross_reference: ChEBI

Axiom
annotated source: photon
annotated property: has_related_synonym
annotated target: Light
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: photon
annotated property: has_related_synonym
annotated target: foton
database_cross_reference: ChEBI

Axiom
annotated source: photon
annotated property: has_related_synonym
annotated target: gamma
database_cross_reference: IUPAC

Axiom
annotated source: photon
annotated property: has_related_synonym
annotated target: hnu
database_cross_reference: IUPAC

Axiom
annotated source: photon
annotated property: has_related_synonym
annotated target: hnu
database_cross_reference: UniProt

Axiom
annotated source: photon
annotated property: has_related_synonym
annotated target: light quantum
database_cross_reference: ChEBI

alpha-particle
type: Class
subclass of: atomic nucleus
subclass of: helium(2+)

helium atom
type: Class
subclass of: noble gas atom
subclass of: s-block element atom

helium-3 atom
type: Class
subclass of: helium atom

neutron
type: Class
subclass of: nucleon

positron
type: Class
subclass of: lepton

isobutyl group
type: Class
subclass of: alkyl group
subclass of: proteinogenic amino-acid side-chain group

monoatomic dication
type: Class
subclass of: monoatomic cation

thallium
type: Class
subclass of: boron group element atom

sulfur hexafluoride
type: Class
subclass of: sulfur coordination entity

silver atom
type: Class
subclass of: copper group element atom

antimony atom
type: Class
subclass of: metalloid atom
subclass of: pnictogen

caesium atom
type: Class
subclass of: alkali metal atom

silicon dioxide
type: Class
subclass of: silicon oxide

formic acid
type: Class
subclass of: monocarboxylic acid

salicylate
type: Class
subclass of: monohydroxybenzoate

alcohol
type: Class
subclass of: organic hydroxy compound

bile acid
type: Class
subclass of: bile acids
subclass of: hydroxy-5beta-cholanic acid
definition: Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration.
database_cross_reference: KEGG:C01558
has_exact_synonym: Bile acid
has_obo_namespace: chebi_ontology
has_related_synonym: 5beta-bile acid
has_related_synonym: 5beta-bile acids
has_related_synonym: Bile salt
has_related_synonym: Gallensaeure
has_related_synonym: Gallensaeuren
has_related_synonym: bile acids
id: CHEBI:3098
in_subset: 3 STAR

Axiom
annotated source: bile acid
annotated property: has_exact_synonym
annotated target: Bile acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bile acid
annotated property: has_related_synonym
annotated target: 5beta-bile acid
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: has_related_synonym
annotated target: 5beta-bile acids
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: has_related_synonym
annotated target: Bile salt
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: bile acid
annotated property: has_related_synonym
annotated target: Gallensaeure
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: has_related_synonym
annotated target: Gallensaeuren
database_cross_reference: ChEBI

Axiom
annotated source: bile acid
annotated property: has_related_synonym
annotated target: bile acids
database_cross_reference: ChEBI

octacosanoic acid
type: Class
subclass of: ultra-long-chain fatty acid
subclass of: straight-chain saturated fatty acid

octacosanoate
type: Class
subclass of: ultra-long-chain fatty acid anion
subclass of: straight-chain saturated fatty acid anion
subclass of: fatty acid anion 28:0

Talc
type: Class
subclass of: organic molecular entity

titanium dioxide
type: Class
subclass of: titanium oxides

barium atom
type: Class
subclass of: alkaline earth metal atom

leucinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: branched-chain amino-acid anion

leucinium
type: Class
subclass of: alpha-amino-acid cation

tertiary amine
type: Class
subclass of: amine
subclass of: tertiary amino compound

amine
type: Class
subclass of: organic amino compound
definition: A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
has_alternative_id: CHEBI:13814
has_alternative_id: CHEBI:22474
has_alternative_id: CHEBI:2641
database_cross_reference: KEGG:C00706
has_exact_synonym: Amine
has_exact_synonym: amines
has_obo_namespace: chebi_ontology
has_related_synonym: Amin
has_related_synonym: Substituted amine
id: CHEBI:32952
in_subset: 3 STAR

Axiom
annotated source: amine
annotated property: has_exact_synonym
annotated target: Amine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: amine
annotated property: has_exact_synonym
annotated target: amines
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: amine
annotated property: has_related_synonym
annotated target: Amin
database_cross_reference: ChEBI

Axiom
annotated source: amine
annotated property: has_related_synonym
annotated target: Substituted amine
database_cross_reference: KEGG_COMPOUND

epoxide
type: Class
subclass of: cyclic ether

amide
type: Class
subclass of: nitrogen molecular entity
definition: An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
has_alternative_id: CHEBI:22473
has_alternative_id: CHEBI:2633
database_cross_reference: KEGG:C00241
has_exact_synonym: Amide
has_exact_synonym: amides
has_obo_namespace: chebi_ontology
id: CHEBI:32988
in_subset: 3 STAR

Axiom
annotated source: amide
annotated property: has_exact_synonym
annotated target: Amide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: amide
annotated property: has_exact_synonym
annotated target: amides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

europium atom
type: Class
subclass of: lanthanoid atom
subclass of: f-block element atom

calcium carbonate
type: Class
subclass of: inorganic calcium salt
subclass of: calcium salt
subclass of: carbonate salt
subclass of: one-carbon compound

application
type: Class
subclass of: realizable
subclass of: role
subclass of: PATO_0000001
definition: Intended use of the molecular entity or part thereof by humans.
has_obo_namespace: chebi_ontology
id: CHEBI:33232
in_subset: 3 STAR

fundamental particle
type: Class
subclass of: subatomic particle
definition: A particle not known to have substructure.
has_exact_synonym: elementary particle
has_obo_namespace: chebi_ontology
has_related_synonym: elementary particles
id: CHEBI:33233
in_subset: 3 STAR

Axiom
annotated source: fundamental particle
annotated property: has_exact_synonym
annotated target: elementary particle
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: fundamental particle
annotated property: has_related_synonym
annotated target: elementary particles
database_cross_reference: ChEBI

monoatomic entity
type: Class
subclass of: elemental molecular entity
definition: A monoatomic entity is a molecular entity consisting of a single atom.
has_obo_namespace: chebi_ontology
has_related_synonym: atomic entity
has_related_synonym: monoatomic entities
id: CHEBI:33238
in_subset: 3 STAR

Axiom
annotated source: monoatomic entity
annotated property: has_related_synonym
annotated target: atomic entity
database_cross_reference: ChEBI

Axiom
annotated source: monoatomic entity
annotated property: has_related_synonym
annotated target: monoatomic entities
database_cross_reference: ChEBI

coordination entity
type: Class
subclass of: heteroatomic molecular entity

oxoacid derivative
type: Class
subclass of: heteroatomic molecular entity
subclass of: Restriction
  on property: has functional parent
  some values from: oxoacid
has_obo_namespace: chebi_ontology
has_related_synonym: oxoacid derivatives
id: CHEBI:33241
in_subset: 3 STAR

Axiom
annotated source: oxoacid derivative
annotated property: has_related_synonym
annotated target: oxoacid derivatives
database_cross_reference: ChEBI

inorganic hydride
type: Class
subclass of: inorganic molecular entity
subclass of: hydrides
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic hydrides
id: CHEBI:33242
in_subset: 3 STAR

Axiom
annotated source: inorganic hydride
annotated property: has_related_synonym
annotated target: inorganic hydrides
database_cross_reference: ChEBI

organic fundamental parent
type: Class
subclass of: organic hydride
subclass of: organic molecular entity
definition: An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.
has_obo_namespace: chebi_ontology
has_related_synonym: organic fundamental parents
has_related_synonym: organic parent hydrides
id: CHEBI:33245
in_subset: 3 STAR

Axiom
annotated source: organic fundamental parent
annotated property: has_related_synonym
annotated target: organic fundamental parents
database_cross_reference: ChEBI

Axiom
annotated source: organic fundamental parent
annotated property: has_related_synonym
annotated target: organic parent hydrides
database_cross_reference: ChEBI

inorganic group
type: Class
subclass of: group
definition: Any substituent group which does not contain carbon.
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic groups
id: CHEBI:33246
in_subset: 3 STAR

Axiom
annotated source: inorganic group
annotated property: has_related_synonym
annotated target: inorganic groups
database_cross_reference: ChEBI

organic group
type: Class
subclass of: group
subclass of: Restriction
  on property: is substituent group from
  some values from: organic molecular entity
definition: Any substituent group or skeleton containing carbon.
has_obo_namespace: chebi_ontology
has_related_synonym: organic groups
id: CHEBI:33247
in_subset: 3 STAR

Axiom
annotated source: organic group
annotated property: has_related_synonym
annotated target: organic groups
database_cross_reference: ChEBI

hydrocarbyl group
type: Class
subclass of: organyl group

organyl group
type: Class
subclass of: organic univalent group
definition: Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.
has_exact_synonym: organyl group
has_exact_synonym: organyl groups
has_obo_namespace: chebi_ontology
has_related_synonym: groupe organyle
has_related_synonym: grupo organilo
has_related_synonym: grupos organilo
id: CHEBI:33249
in_subset: 3 STAR

Axiom
annotated source: organyl group
annotated property: has_exact_synonym
annotated target: organyl group
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: organyl group
annotated property: has_exact_synonym
annotated target: organyl groups
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: organyl group
annotated property: has_related_synonym
annotated target: groupe organyle
database_cross_reference: IUPAC

Axiom
annotated source: organyl group
annotated property: has_related_synonym
annotated target: grupo organilo
database_cross_reference: IUPAC

Axiom
annotated source: organyl group
annotated property: has_related_synonym
annotated target: grupos organilo
database_cross_reference: IUPAC

atom
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: electron
subclass of: Restriction
  on property: has part
  some values from: atomic nucleus
definition: A chemical entity constituting the smallest component of an element having the chemical properties of the element.
has_alternative_id: CHEBI:22671
has_alternative_id: CHEBI:23907
has_exact_synonym: atom
has_obo_namespace: chebi_ontology
has_related_synonym: atome
has_related_synonym: atomo
has_related_synonym: atoms
has_related_synonym: atomus
has_related_synonym: element
has_related_synonym: elements
id: CHEBI:33250
in_subset: 3 STAR

Axiom
annotated source: atom
annotated property: has_exact_synonym
annotated target: atom
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: atom
annotated property: has_related_synonym
annotated target: atome
database_cross_reference: IUPAC

Axiom
annotated source: atom
annotated property: has_related_synonym
annotated target: atomo
database_cross_reference: IUPAC

Axiom
annotated source: atom
annotated property: has_related_synonym
annotated target: atoms
database_cross_reference: ChEBI

Axiom
annotated source: atom
annotated property: has_related_synonym
annotated target: atomus
database_cross_reference: ChEBI

Axiom
annotated source: atom
annotated property: has_related_synonym
annotated target: element
database_cross_reference: ChEBI

Axiom
annotated source: atom
annotated property: has_related_synonym
annotated target: elements
database_cross_reference: ChEBI

monoatomic hydrogen
type: Class
subclass of: monoatomic entity
subclass of: elemental hydrogen

atomic nucleus
type: Class
subclass of: nuclear particle
subclass of: Restriction
  on property: has part
  some values from: nucleon
definition: A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
has_exact_synonym: nucleus
has_obo_namespace: chebi_ontology
has_related_synonym: Atomkern
has_related_synonym: Kern
has_related_synonym: noyau
has_related_synonym: noyau atomique
has_related_synonym: nuclei
has_related_synonym: nucleo
has_related_synonym: nucleo atomico
has_related_synonym: nucleus atomi
id: CHEBI:33252
in_subset: 3 STAR

Axiom
annotated source: atomic nucleus
annotated property: has_exact_synonym
annotated target: nucleus
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: Atomkern
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: Kern
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: noyau
database_cross_reference: IUPAC

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: noyau atomique
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: nuclei
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: nucleo
database_cross_reference: IUPAC

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: nucleo atomico
database_cross_reference: ChEBI

Axiom
annotated source: atomic nucleus
annotated property: has_related_synonym
annotated target: nucleus atomi
database_cross_reference: ChEBI

nucleon
type: Class
subclass of: baryon
subclass of: nuclear particle
definition: Heavy nuclear particle: proton or neutron.
has_exact_synonym: nucleon
has_obo_namespace: chebi_ontology
has_related_synonym: Nukleon
has_related_synonym: Nukleonen
has_related_synonym: nucleons
id: CHEBI:33253
in_subset: 3 STAR

Axiom
annotated source: nucleon
annotated property: has_exact_synonym
annotated target: nucleon
database_cross_reference: IUPAC

Axiom
annotated source: nucleon
annotated property: has_exact_synonym
annotated target: nucleon
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: nucleon
annotated property: has_related_synonym
annotated target: Nukleon
database_cross_reference: ChEBI

Axiom
annotated source: nucleon
annotated property: has_related_synonym
annotated target: Nukleonen
database_cross_reference: ChEBI

Axiom
annotated source: nucleon
annotated property: has_related_synonym
annotated target: nucleons
database_cross_reference: ChEBI

primary amide
type: Class
subclass of: amide
definition: A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
has_exact_synonym: primary amide
has_exact_synonym: primary amides
has_obo_namespace: chebi_ontology
id: CHEBI:33256
in_subset: 3 STAR

Axiom
annotated source: primary amide
annotated property: has_exact_synonym
annotated target: primary amide
database_cross_reference: IUPAC

Axiom
annotated source: primary amide
annotated property: has_exact_synonym
annotated target: primary amides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

elemental molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity all atoms of which have the same atomic number.
has_obo_namespace: chebi_ontology
has_related_synonym: homoatomic entity
has_related_synonym: homoatomic molecular entities
has_related_synonym: homoatomic molecular entity
id: CHEBI:33259
in_subset: 3 STAR

Axiom
annotated source: elemental molecular entity
annotated property: has_related_synonym
annotated target: homoatomic entity
database_cross_reference: ChEBI

Axiom
annotated source: elemental molecular entity
annotated property: has_related_synonym
annotated target: homoatomic molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: elemental molecular entity
annotated property: has_related_synonym
annotated target: homoatomic molecular entity
database_cross_reference: ChEBI

elemental hydrogen
type: Class
subclass of: inorganic molecular entity
subclass of: elemental molecular entity
subclass of: hydrogen molecular entity

organosulfur compound
type: Class
subclass of: sulfur molecular entity
subclass of: organochalcogen compound

elemental oxygen
type: Class
subclass of: inorganic molecular entity
subclass of: oxygen molecular entity
subclass of: elemental molecular entity
has_obo_namespace: chebi_ontology
id: CHEBI:33262
in_subset: 3 STAR

diatomic oxygen
type: Class
subclass of: elemental oxygen
charge: 0
formula: O2
mass: 31.999
monoisotopicmass: 31.98983
has_obo_namespace: chebi_ontology
id: CHEBI:33263
in_subset: 3 STAR

triatomic oxygen
type: Class
subclass of: elemental oxygen

diatomic nitrogen
type: Class
subclass of: elemental nitrogen

elemental nitrogen
type: Class
subclass of: elemental pnictogen
subclass of: nitrogen molecular entity

polyatomic anion
type: Class
subclass of: anion
subclass of: polyatomic ion
definition: An anion consisting of more than one atom.
has_obo_namespace: chebi_ontology
has_related_synonym: polyatomic anions
id: CHEBI:33273
in_subset: 3 STAR

Axiom
annotated source: polyatomic anion
annotated property: has_related_synonym
annotated target: polyatomic anions
database_cross_reference: ChEBI

molecular messenger
type: Class
subclass of: biological role
has_obo_namespace: chebi_ontology
has_related_synonym: chemical messenger
id: CHEBI:33280
in_subset: 3 STAR

Axiom
annotated source: molecular messenger
annotated property: has_related_synonym
annotated target: chemical messenger
database_cross_reference: ChEBI

antimicrobial agent
type: Class
subclass of: biological role
definition: A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
has_alternative_id: CHEBI:22582
database_cross_reference: PMID:12964249
database_cross_reference: PMID:22117953
database_cross_reference: PMID:22439833
database_cross_reference: PMID:22849268
database_cross_reference: PMID:22849276
database_cross_reference: PMID:22958833
has_obo_namespace: chebi_ontology
has_related_synonym: Antibiotika
has_related_synonym: Antibiotikum
has_related_synonym: antibiotic
has_related_synonym: antibiotics
has_related_synonym: antibiotique
has_related_synonym: antimicrobial
has_related_synonym: antimicrobial agents
has_related_synonym: antimicrobials
has_related_synonym: microbicide
has_related_synonym: microbicides
id: CHEBI:33281
in_subset: 3 STAR

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:12964249
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22117953
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22439833
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22849268
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22849276
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: database_cross_reference
annotated target: PMID:22958833
source: Europe PMC

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: Antibiotika
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: Antibiotikum
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: antibiotic
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: antibiotics
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: antibiotique
database_cross_reference: IUPAC

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: antimicrobial
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: antimicrobial agents
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: antimicrobials
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: microbicide
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial agent
annotated property: has_related_synonym
annotated target: microbicides
database_cross_reference: ChEBI

nutrient
type: Class
subclass of: food component
definition: A nutrient is a food component that an organism uses to survive and grow.
has_obo_namespace: chebi_ontology
has_related_synonym: nutrients
id: CHEBI:33284
in_subset: 3 STAR

Axiom
annotated source: nutrient
annotated property: has_related_synonym
annotated target: nutrients
database_cross_reference: ChEBI

heteroorganic entity
type: Class
subclass of: organic molecular entity
definition: A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
has_obo_namespace: chebi_ontology
has_related_synonym: heteroorganic entities
has_related_synonym: organoelement compounds
id: CHEBI:33285
in_subset: 3 STAR

Axiom
annotated source: heteroorganic entity
annotated property: has_related_synonym
annotated target: heteroorganic entities
database_cross_reference: ChEBI

Axiom
annotated source: heteroorganic entity
annotated property: has_related_synonym
annotated target: organoelement compounds
database_cross_reference: ChEBI

agrochemical
type: Class
subclass of: application
definition: An agrochemical is a substance that is used in agriculture or horticulture.
database_cross_reference: Wikipedia:Agrochemical
has_obo_namespace: chebi_ontology
has_related_synonym: agrichemical
has_related_synonym: agrichemicals
has_related_synonym: agricultural chemicals
has_related_synonym: agrochemicals
id: CHEBI:33286
in_subset: 3 STAR

Axiom
annotated source: agrochemical
annotated property: has_related_synonym
annotated target: agrichemical
database_cross_reference: ChEBI

Axiom
annotated source: agrochemical
annotated property: has_related_synonym
annotated target: agrichemicals
database_cross_reference: ChEBI

Axiom
annotated source: agrochemical
annotated property: has_related_synonym
annotated target: agricultural chemicals
database_cross_reference: ChEBI

Axiom
annotated source: agrochemical
annotated property: has_related_synonym
annotated target: agrochemicals
database_cross_reference: ChEBI

fertilizer
type: Class
subclass of: agrochemical
definition: A fertilizer is any substance that is added to soil or water to assist the growth of plants.
has_obo_namespace: chebi_ontology
has_related_synonym: fertiliser
has_related_synonym: fertilizers
id: CHEBI:33287
in_subset: 3 STAR

Axiom
annotated source: fertilizer
annotated property: has_related_synonym
annotated target: fertiliser
database_cross_reference: ChEBI

Axiom
annotated source: fertilizer
annotated property: has_related_synonym
annotated target: fertilizers
database_cross_reference: ChEBI

food
type: Class
subclass of: physiological role

fuel
type: Class
subclass of: application

alkali metal molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: alkali metal atom
definition: A molecular entity containing one or more atoms of an alkali metal.
has_obo_namespace: chebi_ontology
has_related_synonym: alkali metal molecular entities
id: CHEBI:33296
in_subset: 3 STAR

Axiom
annotated source: alkali metal molecular entity
annotated property: has_related_synonym
annotated target: alkali metal molecular entities
database_cross_reference: ChEBI

alkaline earth molecular entity
type: Class
subclass of: s-block molecular entity

pnictogen
type: Class
subclass of: p-block element atom
definition: Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.
has_exact_synonym: pnictogens
has_obo_namespace: chebi_ontology
has_related_synonym: group 15 elements
has_related_synonym: group V elements
has_related_synonym: nitrogenoideos
has_related_synonym: nitrogenoides
has_related_synonym: pnictogene
has_related_synonym: pnictogenes
id: CHEBI:33300
in_subset: 3 STAR

Axiom
annotated source: pnictogen
annotated property: has_exact_synonym
annotated target: pnictogens
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: pnictogen
annotated property: has_related_synonym
annotated target: group 15 elements
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: has_related_synonym
annotated target: group V elements
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: has_related_synonym
annotated target: nitrogenoideos
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: has_related_synonym
annotated target: nitrogenoides
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: has_related_synonym
annotated target: pnictogene
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen
annotated property: has_related_synonym
annotated target: pnictogenes
database_cross_reference: ChEBI

pnictogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: pnictogen
definition: A p-block molecular entity containing any pnictogen.
has_exact_synonym: pnictogen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: pnictogen molecular entities
id: CHEBI:33302
in_subset: 3 STAR

Axiom
annotated source: pnictogen molecular entity
annotated property: has_exact_synonym
annotated target: pnictogen molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen molecular entity
annotated property: has_related_synonym
annotated target: pnictogen molecular entities
database_cross_reference: ChEBI

chalcogen
type: Class
subclass of: p-block element atom
definition: Any p-block element belonging to the group 16 family of the periodic table.
database_cross_reference: PMID:17084588
has_exact_synonym: chalcogen
has_exact_synonym: chalcogens
has_obo_namespace: chebi_ontology
has_related_synonym: Chalkogen
has_related_synonym: Chalkogene
has_related_synonym: anfigeno
has_related_synonym: anfigenos
has_related_synonym: calcogeno
has_related_synonym: calcogenos
has_related_synonym: chalcogene
has_related_synonym: chalcogenes
has_related_synonym: group 16 elements
has_related_synonym: group VI elements
id: CHEBI:33303
in_subset: 3 STAR

Axiom
annotated source: chalcogen
annotated property: database_cross_reference
annotated target: PMID:17084588
source: Europe PMC

Axiom
annotated source: chalcogen
annotated property: has_exact_synonym
annotated target: chalcogen
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: chalcogen
annotated property: has_exact_synonym
annotated target: chalcogens
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: Chalkogen
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: Chalkogene
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: anfigeno
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: anfigenos
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: calcogeno
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: calcogenos
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: chalcogene
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: chalcogenes
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: group 16 elements
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen
annotated property: has_related_synonym
annotated target: group VI elements
database_cross_reference: ChEBI

chalcogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: chalcogen
definition: Any p-block molecular entity containing a chalcogen.
has_exact_synonym: chalcogen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: chalcogen compounds
has_related_synonym: chalcogen molecular entities
id: CHEBI:33304
in_subset: 3 STAR

Axiom
annotated source: chalcogen molecular entity
annotated property: has_exact_synonym
annotated target: chalcogen molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen molecular entity
annotated property: has_related_synonym
annotated target: chalcogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen molecular entity
annotated property: has_related_synonym
annotated target: chalcogen molecular entities
database_cross_reference: ChEBI

carbon group element atom
type: Class
subclass of: p-block element atom
has_exact_synonym: group 14 elements
has_obo_namespace: chebi_ontology
has_related_synonym: carbon group element
has_related_synonym: carbon group elements
has_related_synonym: carbonoides
has_related_synonym: cristallogene
has_related_synonym: cristallogenes
has_related_synonym: group IV elements
id: CHEBI:33306
in_subset: 3 STAR

Axiom
annotated source: carbon group element atom
annotated property: has_exact_synonym
annotated target: group 14 elements
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbon group element atom
annotated property: has_related_synonym
annotated target: carbon group element
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: has_related_synonym
annotated target: carbon group elements
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: has_related_synonym
annotated target: carbonoides
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: has_related_synonym
annotated target: cristallogene
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: has_related_synonym
annotated target: cristallogenes
database_cross_reference: ChEBI

Axiom
annotated source: carbon group element atom
annotated property: has_related_synonym
annotated target: group IV elements
database_cross_reference: ChEBI

carboxylic ester
type: Class
subclass of: ester
subclass of: carbonyl compound
definition: An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.
charge: 0
formula: CO2R2
mass: 44.010
monoisotopicmass: 43.98983
smiles: [*]C(=O)O[*]
has_alternative_id: CHEBI:13204
has_alternative_id: CHEBI:23028
has_alternative_id: CHEBI:3408
database_cross_reference: KEGG:C02391
database_cross_reference: Wikipedia:Ester
has_exact_synonym: Carboxylic ester
has_exact_synonym: carboxylic esters
has_obo_namespace: chebi_ontology
has_related_synonym: a carboxylic ester
has_related_synonym: carboxylic acid esters
id: CHEBI:33308
in_subset: 3 STAR

Axiom
annotated source: carboxylic ester
annotated property: has_exact_synonym
annotated target: Carboxylic ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: carboxylic ester
annotated property: has_exact_synonym
annotated target: carboxylic esters
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carboxylic ester
annotated property: has_related_synonym
annotated target: a carboxylic ester
database_cross_reference: UniProt

Axiom
annotated source: carboxylic ester
annotated property: has_related_synonym
annotated target: carboxylic acid esters
database_cross_reference: ChEBI

noble gas atom
type: Class
subclass of: gas molecular entity
subclass of: nonmetal atom
subclass of: main group element atom

monoatomic helium
type: Class
subclass of: monoatomic entity
subclass of: elemental helium

helium(2+)
type: Class
subclass of: monoatomic dication
subclass of: monoatomic helium

boron group element atom
type: Class
subclass of: p-block element atom

main group element atom
type: Class
subclass of: atom
definition: An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.
has_exact_synonym: main group elements
has_obo_namespace: chebi_ontology
has_related_synonym: Hauptgruppenelement
has_related_synonym: Hauptgruppenelemente
has_related_synonym: main group element
id: CHEBI:33318
in_subset: 3 STAR

Axiom
annotated source: main group element atom
annotated property: has_exact_synonym
annotated target: main group elements
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: main group element atom
annotated property: has_related_synonym
annotated target: Hauptgruppenelement
database_cross_reference: ChEBI

Axiom
annotated source: main group element atom
annotated property: has_related_synonym
annotated target: Hauptgruppenelemente
database_cross_reference: ChEBI

Axiom
annotated source: main group element atom
annotated property: has_related_synonym
annotated target: main group element
database_cross_reference: ChEBI

lanthanoid atom
type: Class
subclass of: rare earth metal atom

rare earth metal atom
type: Class
subclass of: transition element atom

strontium atom
type: Class
subclass of: alkaline earth metal atom

silicon oxide
type: Class
subclass of: inorganic oxide
subclass of: silicon molecular entity

silicon oxoacid
type: Class
subclass of: oxoacid
subclass of: silicon hydroxide

yttrium atom
type: Class
subclass of: rare earth metal atom
subclass of: scandium group element atom
subclass of: d-block element atom

scandium group element atom
type: Class
subclass of: transition element atom

lanthanum atom
type: Class
subclass of: lanthanoid atom
subclass of: scandium group element atom
subclass of: f-block element atom

zinc group element atom
type: Class
subclass of: d-block element atom

titanium atom
type: Class
subclass of: titanium group element atom

niobium atom
type: Class
subclass of: vanadium group element atom

titanium group element atom
type: Class
subclass of: d-block element atom

vanadium group element atom
type: Class
subclass of: d-block element atom

chromium group element atom
type: Class
subclass of: d-block element atom

manganese group element atom
type: Class
subclass of: d-block element atom

iron group element atom
type: Class
subclass of: d-block element atom
has_exact_synonym: group 8 elements
has_related_synonym: iron group element
has_related_synonym: iron group elements

cobalt group element atom
type: Class
subclass of: d-block element atom

nickel group element atom
type: Class
subclass of: d-block element atom

copper group element atom
type: Class
subclass of: d-block element atom

cerium
type: Class
subclass of: lanthanoid atom
subclass of: f-block element atom

neodymium atom
type: Class
subclass of: lanthanoid atom
subclass of: f-block element atom

samarium atom
type: Class
subclass of: lanthanoid atom
subclass of: f-block element atom

gadolinium atom
type: Class
subclass of: lanthanoid atom
subclass of: f-block element atom

dysprosium atom
type: Class
subclass of: lanthanoid atom
subclass of: f-block element atom

platinum(0)
type: Class
subclass of: elemental platinum

sulfur oxoacid
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoacid
has_obo_namespace: chebi_ontology
has_related_synonym: oxoacids of sulfur
has_related_synonym: sulfur oxoacids
id: CHEBI:33402
in_subset: 3 STAR

Axiom
annotated source: sulfur oxoacid
annotated property: has_related_synonym
annotated target: oxoacids of sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoacid
annotated property: has_related_synonym
annotated target: sulfur oxoacids
database_cross_reference: ChEBI

hydracid
type: Class
subclass of: hydrogen molecular entity

pnictogen oxoacid
type: Class
subclass of: oxoacid
subclass of: pnictogen molecular entity
subclass of: Restriction
  on property: has role
  some values from: inorganic acid
has_obo_namespace: chebi_ontology
has_related_synonym: pnictogen oxoacids
id: CHEBI:33408
in_subset: 3 STAR

Axiom
annotated source: pnictogen oxoacid
annotated property: has_related_synonym
annotated target: pnictogen oxoacids
database_cross_reference: ChEBI

elemental carbon
type: Class
subclass of: elemental molecular entity
subclass of: organic molecular entity

sulfur oxoacid derivative
type: Class
subclass of: sulfur molecular entity
subclass of: oxoacid derivative
has_exact_synonym: sulfur oxoacid derivative
has_obo_namespace: chebi_ontology
has_related_synonym: sulfur oxoacid derivatives
id: CHEBI:33424
in_subset: 3 STAR

Axiom
annotated source: sulfur oxoacid derivative
annotated property: has_exact_synonym
annotated target: sulfur oxoacid derivative
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoacid derivative
annotated property: has_related_synonym
annotated target: sulfur oxoacid derivatives
database_cross_reference: ChEBI

monoatomic monoanion
type: Class
subclass of: monoatomic anion
subclass of: monoanion

elemental chlorine
type: Class
subclass of: chlorine molecular entity
subclass of: elemental halogen

monoatomic chlorine
type: Class
subclass of: elemental chlorine
subclass of: monoatomic halogen

monoatomic halogen
type: Class
subclass of: monoatomic entity

elemental halogen
type: Class
subclass of: elemental molecular entity

phospho sugar
type: Class
subclass of: carbohydrate phosphate
subclass of: monosaccharide derivative

nitrogen oxoacid
type: Class
subclass of: pnictogen oxoacid
subclass of: nitrogen molecular entity

phosphorus oxoacid
type: Class
subclass of: pnictogen oxoacid
subclass of: phosphorus oxoacids and derivatives
definition: A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons.
has_exact_synonym: phosphorus oxoacid
has_obo_namespace: chebi_ontology
has_related_synonym: Oxosaeure des Phosphors
has_related_synonym: oxoacids of phosphorus
has_related_synonym: phosphorus oxoacids
id: CHEBI:33457
in_subset: 3 STAR

Axiom
annotated source: phosphorus oxoacid
annotated property: has_exact_synonym
annotated target: phosphorus oxoacid
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus oxoacid
annotated property: has_related_synonym
annotated target: Oxosaeure des Phosphors
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus oxoacid
annotated property: has_related_synonym
annotated target: oxoacids of phosphorus
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus oxoacid
annotated property: has_related_synonym
annotated target: phosphorus oxoacids
database_cross_reference: ChEBI

nitrogen oxoanion
type: Class
subclass of: pnictogen oxoanion
subclass of: nitrogen molecular entity

pnictogen oxoanion
type: Class
subclass of: pnictogen molecular entity
subclass of: oxoanion
has_exact_synonym: pnictogen oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: pnictogen oxoanions
id: CHEBI:33459
in_subset: 3 STAR

Axiom
annotated source: pnictogen oxoanion
annotated property: has_exact_synonym
annotated target: pnictogen oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen oxoanion
annotated property: has_related_synonym
annotated target: pnictogen oxoanions
database_cross_reference: ChEBI

phosphorus oxoanion
type: Class
subclass of: inorganic anion
subclass of: phosphorus molecular entity
subclass of: pnictogen oxoanion
has_exact_synonym: phosphorus oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: oxoanions of phosphorus
has_related_synonym: phosphorus oxoanions
id: CHEBI:33461
in_subset: 3 STAR

Axiom
annotated source: phosphorus oxoanion
annotated property: has_exact_synonym
annotated target: phosphorus oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus oxoanion
annotated property: has_related_synonym
annotated target: oxoanions of phosphorus
database_cross_reference: ChEBI

Axiom
annotated source: phosphorus oxoanion
annotated property: has_related_synonym
annotated target: phosphorus oxoanions
database_cross_reference: ChEBI

elemental pnictogen
type: Class
subclass of: inorganic molecular entity
subclass of: elemental molecular entity
subclass of: pnictogen molecular entity

sulfur oxoanion
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoanion
has_exact_synonym: sulfur oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: oxoanions of sulfur
has_related_synonym: sulfur oxoanions
id: CHEBI:33482
in_subset: 3 STAR

Axiom
annotated source: sulfur oxoanion
annotated property: has_exact_synonym
annotated target: sulfur oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoanion
annotated property: has_related_synonym
annotated target: oxoanions of sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxoanion
annotated property: has_related_synonym
annotated target: sulfur oxoanions
database_cross_reference: ChEBI

chalcogen oxoacid
type: Class
subclass of: oxoacid
subclass of: Restriction
  on property: has role
  some values from: inorganic acid
has_exact_synonym: chalcogen oxoacid
has_obo_namespace: chebi_ontology
has_related_synonym: chalcogen oxoacids
id: CHEBI:33484
in_subset: 3 STAR

Axiom
annotated source: chalcogen oxoacid
annotated property: has_exact_synonym
annotated target: chalcogen oxoacid
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen oxoacid
annotated property: has_related_synonym
annotated target: chalcogen oxoacids
database_cross_reference: ChEBI

chalcogen oxoanion
type: Class
subclass of: oxoanion
has_exact_synonym: chalcogen oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: chalcogen oxoanions
id: CHEBI:33485
in_subset: 3 STAR

Axiom
annotated source: chalcogen oxoanion
annotated property: has_exact_synonym
annotated target: chalcogen oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen oxoanion
annotated property: has_related_synonym
annotated target: chalcogen oxoanions
database_cross_reference: ChEBI

transition element molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity containing one or more atoms of a transition element.
has_related_synonym: transition element molecular entities
has_related_synonym: transition metal molecular entity

actinoid molecular entity
type: Class
subclass of: f-block molecular entity

uranium molecular entity
type: Class
subclass of: actinoid molecular entity

alkali metal cation
type: Class
subclass of: metal cation
has_obo_namespace: chebi_ontology
has_related_synonym: alkali metal cations
id: CHEBI:33504
in_subset: 3 STAR

Axiom
annotated source: alkali metal cation
annotated property: has_related_synonym
annotated target: alkali metal cations
database_cross_reference: ChEBI

metal atom
type: Class
subclass of: atom
definition: An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.
has_alternative_id: CHEBI:25217
has_alternative_id: CHEBI:6788
database_cross_reference: KEGG:C00050
database_cross_reference: PMID:21784043
database_cross_reference: Wikipedia:Metal
has_obo_namespace: chebi_ontology
has_related_synonym: elemental metal
has_related_synonym: elemental metals
has_related_synonym: metal element
has_related_synonym: metal elements
has_related_synonym: metals
id: CHEBI:33521
in_subset: 3 STAR

Axiom
annotated source: metal atom
annotated property: database_cross_reference
annotated target: PMID:21784043
source: Europe PMC

Axiom
annotated source: metal atom
annotated property: has_related_synonym
annotated target: elemental metal
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: has_related_synonym
annotated target: elemental metals
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: has_related_synonym
annotated target: metal element
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: has_related_synonym
annotated target: metal elements
database_cross_reference: ChEBI

Axiom
annotated source: metal atom
annotated property: has_related_synonym
annotated target: metals
database_cross_reference: ChEBI

sulfur hydride
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen hydride

organosulfonic acid
type: Class
subclass of: organosulfur compound
subclass of: sulfonic acid derivative
subclass of: organic acid

sulfonic acid derivative
type: Class
subclass of: sulfur oxoacid derivative

alpha-amino-acid anion
type: Class
subclass of: amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: alpha-amino acid
definition: An amino-acid anion obtained by deprotonation of any alpha-amino acid.
has_exact_synonym: alpha-amino-acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-amino acid anions
has_related_synonym: alpha-amino-acid anions
id: CHEBI:33558
in_subset: 3 STAR

Axiom
annotated source: alpha-amino-acid anion
annotated property: has_exact_synonym
annotated target: alpha-amino-acid anion
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid anion
annotated property: has_related_synonym
annotated target: alpha-amino acid anions
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino-acid anion
annotated property: has_related_synonym
annotated target: alpha-amino-acid anions
database_cross_reference: ChEBI

s-block element atom
type: Class
subclass of: atom
has_obo_namespace: chebi_ontology
has_related_synonym: s-block element
has_related_synonym: s-block elements
id: CHEBI:33559
in_subset: 3 STAR

Axiom
annotated source: s-block element atom
annotated property: has_related_synonym
annotated target: s-block element
database_cross_reference: ChEBI

Axiom
annotated source: s-block element atom
annotated property: has_related_synonym
annotated target: s-block elements
database_cross_reference: ChEBI

p-block element atom
type: Class
subclass of: main group element atom
definition: Any main group element atom belonging to the p-block of the periodic table.
has_obo_namespace: chebi_ontology
has_related_synonym: p-block element
has_related_synonym: p-block elements
id: CHEBI:33560
in_subset: 3 STAR

Axiom
annotated source: p-block element atom
annotated property: has_related_synonym
annotated target: p-block element
database_cross_reference: ChEBI

Axiom
annotated source: p-block element atom
annotated property: has_related_synonym
annotated target: p-block elements
database_cross_reference: ChEBI

d-block element atom
type: Class
subclass of: transition element atom
has_related_synonym: d-block element
has_related_synonym: d-block elements

f-block element atom
type: Class
subclass of: transition element atom

catechols
type: Class
subclass of: benzenediols
definition: Any compound containing an o-diphenol component.
charge: 0
formula: C6H2O2R4
mass: 106.079
monoisotopicmass: 106.00548
smiles: OC1=C(O)C(*)=C(*)C(*)=C1*
has_alternative_id: CHEBI:134187
has_alternative_id: CHEBI:13628
has_alternative_id: CHEBI:18862
database_cross_reference: KEGG:C15571
has_obo_namespace: chebi_ontology
has_related_synonym: 1,2-benzenediols
has_related_synonym: a catechol
has_related_synonym: benzene-1,2-diols
id: CHEBI:33566
in_subset: 3 STAR

Axiom
annotated source: catechols
annotated property: has_related_synonym
annotated target: 1,2-benzenediols
database_cross_reference: ChEBI

Axiom
annotated source: catechols
annotated property: has_related_synonym
annotated target: a catechol
database_cross_reference: UniProt

Axiom
annotated source: catechols
annotated property: has_related_synonym
annotated target: benzene-1,2-diols
database_cross_reference: ChEBI

catecholamine
type: Class
subclass of: monoamine molecular messenger
subclass of: catechols
definition: 4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
charge: 0
formula: C8H9NO2R2
mass: 151.163
monoisotopicmass: 151.06333
has_alternative_id: CHEBI:23056
has_alternative_id: CHEBI:3468
database_cross_reference: KEGG:C02012
has_exact_synonym: Catecholamine
has_exact_synonym: catecholamines
has_obo_namespace: chebi_ontology
has_related_synonym: catecholamines
id: CHEBI:33567
in_subset: 3 STAR

Axiom
annotated source: catecholamine
annotated property: has_exact_synonym
annotated target: Catecholamine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: catecholamine
annotated property: has_exact_synonym
annotated target: catecholamines
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: catecholamine
annotated property: has_related_synonym
annotated target: catecholamines
database_cross_reference: ChEBI

noradrenaline
type: Class
subclass of: catecholamine
subclass of: Restriction
  on property: has role
  some values from: human xenobiotic metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: noradrenaline(1+)
definition: A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted.
charge: 0
formula: C8H11NO3
inchi: InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2
inchikey: SFLSHLFXELFNJZ-UHFFFAOYSA-N
mass: 169.17788
monoisotopicmass: 169.07389
smiles: NCC(O)c1ccc(O)c(O)c1
database_cross_reference: Beilstein:2210994
database_cross_reference: CAS:138-65-8
database_cross_reference: Gmelin:863925
database_cross_reference: LINCS:LSM-5181
has_exact_synonym: 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
has_obo_namespace: chebi_ontology
has_related_synonym: noradrenalina
has_related_synonym: norepinephrine
id: CHEBI:33569
in_subset: 3 STAR

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: Beilstein:2210994
source: Beilstein

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: CAS:138-65-8
source: ChemIDplus

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: CAS:138-65-8
source: NIST Chemistry WebBook

Axiom
annotated source: noradrenaline
annotated property: database_cross_reference
annotated target: Gmelin:863925
source: Gmelin

Axiom
annotated source: noradrenaline
annotated property: has_exact_synonym
annotated target: 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: noradrenaline
annotated property: has_related_synonym
annotated target: noradrenalina
database_cross_reference: ChEBI

Axiom
annotated source: noradrenaline
annotated property: has_related_synonym
annotated target: norepinephrine
database_cross_reference: ChEBI

benzenediols
type: Class
subclass of: phenols
has_alternative_id: CHEBI:22705
has_alternative_id: CHEBI:22711
has_obo_namespace: chebi_ontology
id: CHEBI:33570
in_subset: 3 STAR

(S)-noradrenaline
type: Class
subclass of: noradrenaline
subclass of: Restriction
  on property: is enantiomer of
  some values from: (R)-noradrenaline
definition: The S-enantiomer of noradrenaline.
charge: 0
formula: C8H11NO3
inchi: InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1
inchikey: SFLSHLFXELFNJZ-MRVPVSSYSA-N
mass: 169.17788
monoisotopicmass: 169.07389
smiles: NC[C@@H](O)c1ccc(O)c(O)c1
database_cross_reference: Beilstein:2937999
database_cross_reference: LINCS:LSM-37072
database_cross_reference: Reaxys:2937999
has_exact_synonym: 4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol
has_obo_namespace: chebi_ontology
id: CHEBI:33571
in_subset: 3 STAR

Axiom
annotated source: (S)-noradrenaline
annotated property: database_cross_reference
annotated target: Beilstein:2937999
source: Beilstein

Axiom
annotated source: (S)-noradrenaline
annotated property: database_cross_reference
annotated target: Reaxys:2937999
source: Reaxys

Axiom
annotated source: (S)-noradrenaline
annotated property: has_exact_synonym
annotated target: 4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

carboxylic acid
type: Class
subclass of: carbon oxoacid
subclass of: carbonyl compound
subclass of: organic acid
subclass of: Restriction
  on property: has part
  some values from: carboxy group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carboxylic acid anion
definition: A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
charge: 0
formula: CHO2R
mass: 45.01740
monoisotopicmass: 44.99765
smiles: OC([*])=O
has_alternative_id: CHEBI:13428
has_alternative_id: CHEBI:13627
has_alternative_id: CHEBI:23027
database_cross_reference: PMID:17147560
database_cross_reference: PMID:18433345
database_cross_reference: Wikipedia:Carboxylic_acid
has_exact_synonym: carboxylic acid
has_exact_synonym: carboxylic acids
has_obo_namespace: chebi_ontology
has_related_synonym: Carbonsaeure
has_related_synonym: Carbonsaeuren
has_related_synonym: Karbonsaeure
has_related_synonym: RC(=O)OH
has_related_synonym: acide carboxylique
has_related_synonym: acides carboxyliques
has_related_synonym: acido carboxilico
has_related_synonym: acidos carboxilicos
id: CHEBI:33575
in_subset: 3 STAR

Axiom
annotated source: carboxylic acid
annotated property: database_cross_reference
annotated target: PMID:17147560
source: Europe PMC

Axiom
annotated source: carboxylic acid
annotated property: database_cross_reference
annotated target: PMID:18433345
source: Europe PMC

Axiom
annotated source: carboxylic acid
annotated property: has_exact_synonym
annotated target: carboxylic acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carboxylic acid
annotated property: has_exact_synonym
annotated target: carboxylic acids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: Carbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: Carbonsaeuren
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: Karbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: RC(=O)OH
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: acide carboxylique
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: acides carboxyliques
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: acido carboxilico
database_cross_reference: IUPAC

Axiom
annotated source: carboxylic acid
annotated property: has_related_synonym
annotated target: acidos carboxilicos
database_cross_reference: IUPAC

main group molecular entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: main group element atom
definition: A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.
has_obo_namespace: chebi_ontology
has_related_synonym: main group compounds
has_related_synonym: main group molecular entities
id: CHEBI:33579
in_subset: 3 STAR

Axiom
annotated source: main group molecular entity
annotated property: has_related_synonym
annotated target: main group compounds
database_cross_reference: ChEBI

Axiom
annotated source: main group molecular entity
annotated property: has_related_synonym
annotated target: main group molecular entities
database_cross_reference: ChEBI

boron group molecular entity
type: Class
subclass of: p-block molecular entity

carbon group molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon group element atom
has_exact_synonym: carbon group molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: carbon group molecular entities
id: CHEBI:33582
in_subset: 3 STAR

Axiom
annotated source: carbon group molecular entity
annotated property: has_exact_synonym
annotated target: carbon group molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: carbon group molecular entity
annotated property: has_related_synonym
annotated target: carbon group molecular entities
database_cross_reference: ChEBI

noble gas molecular entity
type: Class
subclass of: main group molecular entity

lead molecular entity
type: Class
subclass of: carbon group molecular entity

cyclic compound
type: Class
subclass of: molecule
definition: Any molecule that consists of a series of atoms joined together to form a ring.
database_cross_reference: Wikipedia:Cyclic_compound
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic compounds
id: CHEBI:33595
in_subset: 3 STAR

Axiom
annotated source: cyclic compound
annotated property: has_related_synonym
annotated target: cyclic compounds
database_cross_reference: ChEBI

homocyclic compound
type: Class
subclass of: cyclic compound

carbocyclic compound
type: Class
subclass of: homocyclic compound
subclass of: organic cyclic compound

hydrogen molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: hydrogen atom
has_obo_namespace: chebi_ontology
has_related_synonym: hydrogen compounds
has_related_synonym: hydrogen molecular entities
id: CHEBI:33608
in_subset: 3 STAR

Axiom
annotated source: hydrogen molecular entity
annotated property: has_related_synonym
annotated target: hydrogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen molecular entity
annotated property: has_related_synonym
annotated target: hydrogen molecular entities
database_cross_reference: ChEBI

aluminium molecular entity
type: Class
subclass of: boron group molecular entity

aluminium oxides
type: Class
subclass of: metal oxide
subclass of: aluminium molecular entity

monoatomic aluminium
type: Class
subclass of: monoatomic entity
subclass of: elemental aluminium

elemental aluminium
type: Class
subclass of: inorganic molecular entity
subclass of: elemental molecular entity
subclass of: aluminium molecular entity

polycyclic compound
type: Class
subclass of: cyclic compound
has_obo_namespace: chebi_ontology
has_related_synonym: polycyclic compounds
id: CHEBI:33635
in_subset: 3 STAR

Axiom
annotated source: polycyclic compound
annotated property: has_related_synonym
annotated target: polycyclic compounds
database_cross_reference: ChEBI

bicyclic compound
type: Class
subclass of: cyclic compound
definition: A molecule that features two fused rings.
has_obo_namespace: chebi_ontology
has_related_synonym: bicyclic compounds
id: CHEBI:33636
in_subset: 3 STAR

Axiom
annotated source: bicyclic compound
annotated property: has_related_synonym
annotated target: bicyclic compounds
database_cross_reference: ChEBI

ortho-fused compound
type: Class
subclass of: fused compound

olefin
type: Class
subclass of: hydrocarbon
subclass of: olefinic compound

acyclic olefin
type: Class
subclass of: olefin

alkadiene
type: Class
subclass of: acyclic olefin

aliphatic compound
type: Class
subclass of: organic molecular entity

aromatic compound
type: Class
subclass of: cyclic compound
definition: A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.
has_exact_synonym: aromatic compounds
has_exact_synonym: aromatic molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: aromatics
has_related_synonym: aromatische Verbindungen
id: CHEBI:33655
in_subset: 3 STAR

Axiom
annotated source: aromatic compound
annotated property: has_exact_synonym
annotated target: aromatic compounds
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: aromatic compound
annotated property: has_exact_synonym
annotated target: aromatic molecular entity
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: aromatic compound
annotated property: has_related_synonym
annotated target: aromatics
database_cross_reference: ChEBI

Axiom
annotated source: aromatic compound
annotated property: has_related_synonym
annotated target: aromatische Verbindungen
database_cross_reference: ChEBI

arene
type: Class
subclass of: organic aromatic compound
subclass of: cyclic hydrocarbon

organic aromatic compound
type: Class
subclass of: aromatic compound
subclass of: organic cyclic compound
has_obo_namespace: chebi_ontology
has_related_synonym: organic aromatic compounds
id: CHEBI:33659
in_subset: 3 STAR

Axiom
annotated source: organic aromatic compound
annotated property: has_related_synonym
annotated target: organic aromatic compounds
database_cross_reference: ChEBI

monocyclic compound
type: Class
subclass of: cyclic compound

annulene
type: Class
subclass of: monocyclic hydrocarbon

cyclic hydrocarbon
type: Class
subclass of: hydrocarbon
subclass of: carbocyclic compound

monocyclic hydrocarbon
type: Class
subclass of: cyclic hydrocarbon

polycyclic hydrocarbon
type: Class
subclass of: cyclic hydrocarbon
subclass of: carbopolycyclic compound

heteromonocyclic compound
type: Class
subclass of: monocyclic compound
subclass of: heterocyclic compound

heteropolycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: heterocyclic compound
definition: A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.
has_exact_synonym: heteropolycyclic compounds
has_obo_namespace: chebi_ontology
has_related_synonym: polyheterocyclic compounds
id: CHEBI:33671
in_subset: 3 STAR

Axiom
annotated source: heteropolycyclic compound
annotated property: has_exact_synonym
annotated target: heteropolycyclic compounds
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: heteropolycyclic compound
annotated property: has_related_synonym
annotated target: polyheterocyclic compounds
database_cross_reference: ChEBI

heterobicyclic compound
type: Class
subclass of: bicyclic compound
subclass of: heterocyclic compound
definition: A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom.
has_exact_synonym: heterobicyclic compounds
has_obo_namespace: chebi_ontology
id: CHEBI:33672
in_subset: 3 STAR

Axiom
annotated source: heterobicyclic compound
annotated property: has_exact_synonym
annotated target: heterobicyclic compounds
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

zinc group molecular entity
type: Class
subclass of: d-block molecular entity

s-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: s-block element atom
definition: An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.
has_exact_synonym: s-block molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: s-block compounds
has_related_synonym: s-block molecular entities
id: CHEBI:33674
in_subset: 3 STAR

Axiom
annotated source: s-block molecular entity
annotated property: has_exact_synonym
annotated target: s-block molecular entity
database_cross_reference: ChEBI

Axiom
annotated source: s-block molecular entity
annotated property: has_related_synonym
annotated target: s-block compounds
database_cross_reference: ChEBI

Axiom
annotated source: s-block molecular entity
annotated property: has_related_synonym
annotated target: s-block molecular entities
database_cross_reference: ChEBI

p-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: p-block element atom
definition: A main group molecular entity that contains one or more atoms of a p-block element.
has_obo_namespace: chebi_ontology
has_related_synonym: p-block compounds
has_related_synonym: p-block molecular entities
has_related_synonym: p-block molecular entitiy
id: CHEBI:33675
in_subset: 3 STAR

Axiom
annotated source: p-block molecular entity
annotated property: has_related_synonym
annotated target: p-block compounds
database_cross_reference: ChEBI

Axiom
annotated source: p-block molecular entity
annotated property: has_related_synonym
annotated target: p-block molecular entities
database_cross_reference: ChEBI

Axiom
annotated source: p-block molecular entity
annotated property: has_related_synonym
annotated target: p-block molecular entitiy
database_cross_reference: ChEBI

d-block molecular entity
type: Class
subclass of: transition element molecular entity
definition: A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element.
has_exact_synonym: d-block molecular entity
has_related_synonym: d-block compounds
has_related_synonym: d-block molecular entities

f-block molecular entity
type: Class
subclass of: transition element molecular entity

helium molecular entity
type: Class
subclass of: noble gas molecular entity
subclass of: s-block molecular entity

elemental helium
type: Class
subclass of: helium molecular entity

diatomic helium
type: Class
subclass of: elemental helium

hydrides
type: Class
subclass of: hydrogen molecular entity
subclass of: heteroatomic molecular entity
definition: Hydrides are chemical compounds of hydrogen with other chemical elements.
has_obo_namespace: chebi_ontology
id: CHEBI:33692
in_subset: 3 STAR

oxygen hydride
type: Class
subclass of: chalcogen hydride
has_exact_synonym: oxygen hydride
has_obo_namespace: chebi_ontology
has_related_synonym: hydrides of oxygen
has_related_synonym: oxygen hydrides
id: CHEBI:33693
in_subset: 3 STAR

Axiom
annotated source: oxygen hydride
annotated property: has_exact_synonym
annotated target: oxygen hydride
database_cross_reference: ChEBI

Axiom
annotated source: oxygen hydride
annotated property: has_related_synonym
annotated target: hydrides of oxygen
database_cross_reference: ChEBI

Axiom
annotated source: oxygen hydride
annotated property: has_related_synonym
annotated target: oxygen hydrides
database_cross_reference: ChEBI

biomacromolecule
type: Class
subclass of: macromolecule
subclass of: organic molecular entity
definition: A macromolecule formed by a living organism.
has_exact_synonym: biopolymer
has_obo_namespace: chebi_ontology
has_related_synonym: Biopolymere
has_related_synonym: biomacromolecules
has_related_synonym: biopolymers
id: CHEBI:33694
in_subset: 3 STAR

Axiom
annotated source: biomacromolecule
annotated property: has_exact_synonym
annotated target: biopolymer
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: biomacromolecule
annotated property: has_related_synonym
annotated target: Biopolymere
database_cross_reference: ChEBI

Axiom
annotated source: biomacromolecule
annotated property: has_related_synonym
annotated target: biomacromolecules
database_cross_reference: ChEBI

Axiom
annotated source: biomacromolecule
annotated property: has_related_synonym
annotated target: biopolymers
database_cross_reference: ChEBI

information biomacromolecule
type: Class
subclass of: biomacromolecule
has_obo_namespace: chebi_ontology
has_related_synonym: genetically encoded biomacromolecules
has_related_synonym: genetically encoded biopolymers
has_related_synonym: information biomacromolecules
has_related_synonym: information biopolymers
has_related_synonym: information macromolecule
has_related_synonym: information macromolecules
id: CHEBI:33695
in_subset: 3 STAR

Axiom
annotated source: information biomacromolecule
annotated property: has_related_synonym
annotated target: genetically encoded biomacromolecules
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: has_related_synonym
annotated target: genetically encoded biopolymers
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: has_related_synonym
annotated target: information biomacromolecules
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: has_related_synonym
annotated target: information biopolymers
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: has_related_synonym
annotated target: information macromolecule
database_cross_reference: ChEBI

Axiom
annotated source: information biomacromolecule
annotated property: has_related_synonym
annotated target: information macromolecules
database_cross_reference: ChEBI

nucleic acid
type: Class
subclass of: polynucleotide
subclass of: Restriction
  on property: has part
  some values from: canonical nucleoside residue
subclass of: Restriction
  on property: has part
  some values from: canonical nucleotide residue
definition: A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.
has_exact_synonym: nucleic acids
has_obo_namespace: chebi_ontology
has_related_synonym: NA
has_related_synonym: Nukleinsaeure
has_related_synonym: Nukleinsaeuren
has_related_synonym: acide nucleique
has_related_synonym: acides nucleiques
has_related_synonym: acido nucleico
has_related_synonym: acidos nucleicos
id: CHEBI:33696
in_subset: 3 STAR

Axiom
annotated source: nucleic acid
annotated property: has_exact_synonym
annotated target: nucleic acids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: nucleic acid
annotated property: has_related_synonym
annotated target: NA
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: has_related_synonym
annotated target: Nukleinsaeure
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: has_related_synonym
annotated target: Nukleinsaeuren
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: has_related_synonym
annotated target: acide nucleique
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: has_related_synonym
annotated target: acides nucleiques
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: has_related_synonym
annotated target: acido nucleico
database_cross_reference: ChEBI

Axiom
annotated source: nucleic acid
annotated property: has_related_synonym
annotated target: acidos nucleicos
database_cross_reference: ChEBI

ribonucleic acid
type: Class
subclass of: nucleic acid
subclass of: Restriction
  on property: has part
  some values from: canonical ribonucleoside residue
subclass of: Restriction
  on property: has part
  some values from: canonical ribonucleotide residue
definition: High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.
database_cross_reference: CAS:63231-63-0
has_exact_synonym: ribonucleic acid
has_exact_synonym: ribonucleic acids
has_obo_namespace: chebi_ontology
has_related_synonym: RNA
has_related_synonym: RNS
has_related_synonym: Ribonukleinsaeure
has_related_synonym: pentosenucleic acids
has_related_synonym: ribonucleic acids
has_related_synonym: ribose nucleic acid
has_related_synonym: yeast nucleic acid
id: CHEBI:33697
in_subset: 3 STAR

Axiom
annotated source: ribonucleic acid
annotated property: database_cross_reference
annotated target: CAS:63231-63-0
source: ChemIDplus

Axiom
annotated source: ribonucleic acid
annotated property: has_exact_synonym
annotated target: ribonucleic acid
database_cross_reference: IUPAC

Axiom
annotated source: ribonucleic acid
annotated property: has_exact_synonym
annotated target: ribonucleic acids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: RNA
database_cross_reference: IUPAC

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: RNA
database_cross_reference: UniProt

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: RNS
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: Ribonukleinsaeure
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: pentosenucleic acids
database_cross_reference: ChemIDplus

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: ribonucleic acids
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: ribose nucleic acid
database_cross_reference: ChEBI

Axiom
annotated source: ribonucleic acid
annotated property: has_related_synonym
annotated target: yeast nucleic acid
database_cross_reference: ChEBI

proteinogenic amino-acid residue
type: Class
subclass of: alpha-amino-acid residue
has_obo_namespace: chebi_ontology
has_related_synonym: canonical amino-acid residue
has_related_synonym: canonical amino-acid residues
has_related_synonym: common amino acid residues
has_related_synonym: proteinogenic amino-acid residues
has_related_synonym: standard amino acid residues
has_related_synonym: standard amino-acid residues
id: CHEBI:33700
in_subset: 3 STAR

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: has_related_synonym
annotated target: canonical amino-acid residue
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: has_related_synonym
annotated target: canonical amino-acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: has_related_synonym
annotated target: common amino acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: has_related_synonym
annotated target: proteinogenic amino-acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: has_related_synonym
annotated target: standard amino acid residues
database_cross_reference: ChEBI

Axiom
annotated source: proteinogenic amino-acid residue
annotated property: has_related_synonym
annotated target: standard amino-acid residues
database_cross_reference: ChEBI

polyatomic cation
type: Class
subclass of: polyatomic ion
subclass of: cation
definition: A cation consisting of more than one atom.
has_obo_namespace: chebi_ontology
has_related_synonym: polyatomic cations
id: CHEBI:33702
in_subset: 3 STAR

Axiom
annotated source: polyatomic cation
annotated property: has_related_synonym
annotated target: polyatomic cations
database_cross_reference: ChEBI

amino-acid cation
type: Class
subclass of: polyatomic cation

alpha-amino acid
type: Class
subclass of: amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alpha-amino-acid anion
subclass of: Restriction
  on property: is tautomer of
  some values from: alpha-amino acid zwitterion
definition: An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group.
charge: 0
formula: C2H4NO2R
mass: 74.05870
monoisotopicmass: 74.02420
smiles: NC([*])C(O)=O
has_alternative_id: CHEBI:10208
has_alternative_id: CHEBI:13779
has_alternative_id: CHEBI:22442
has_alternative_id: CHEBI:2642
database_cross_reference: KEGG:C00045
database_cross_reference: KEGG:C05167
has_exact_synonym: alpha-amino acid
has_obo_namespace: chebi_ontology
has_related_synonym: Amino acid
has_related_synonym: Amino acids
has_related_synonym: alpha-amino acids
has_related_synonym: alpha-amino carboxylic acids
id: CHEBI:33704
in_subset: 3 STAR

Axiom
annotated source: alpha-amino acid
annotated property: has_exact_synonym
annotated target: alpha-amino acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: alpha-amino acid
annotated property: has_related_synonym
annotated target: Amino acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: alpha-amino acid
annotated property: has_related_synonym
annotated target: Amino acids
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: alpha-amino acid
annotated property: has_related_synonym
annotated target: alpha-amino acids
database_cross_reference: ChEBI

Axiom
annotated source: alpha-amino acid
annotated property: has_related_synonym
annotated target: alpha-amino acids
database_cross_reference: JCBN

Axiom
annotated source: alpha-amino acid
annotated property: has_related_synonym
annotated target: alpha-amino carboxylic acids
database_cross_reference: IUPAC

amino-acid residue
type: Class
subclass of: organic group
subclass of: Restriction
  on property: is substituent group from
  some values from: amino acid
definition: When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.
has_exact_synonym: amino-acid residue
has_obo_namespace: chebi_ontology
has_related_synonym: amino acid residue
has_related_synonym: amino-acid residues
id: CHEBI:33708
in_subset: 3 STAR

Axiom
annotated source: amino-acid residue
annotated property: has_exact_synonym
annotated target: amino-acid residue
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: amino-acid residue
annotated property: has_related_synonym
annotated target: amino acid residue
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid residue
annotated property: has_related_synonym
annotated target: amino-acid residues
database_cross_reference: JCBN

amino acid
type: Class
subclass of: carboxylic acid
subclass of: organic amino compound
subclass of: Restriction
  on property: is conjugate acid of
  some values from: amino-acid anion
definition: A carboxylic acid containing one or more amino groups.
has_alternative_id: CHEBI:13815
has_alternative_id: CHEBI:22477
database_cross_reference: Wikipedia:Amino_acid
has_obo_namespace: chebi_ontology
has_related_synonym: Aminocarbonsaeure
has_related_synonym: Aminokarbonsaeure
has_related_synonym: Aminosaeure
has_related_synonym: amino acids
id: CHEBI:33709
in_subset: 3 STAR

Axiom
annotated source: amino acid
annotated property: has_related_synonym
annotated target: Aminocarbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: amino acid
annotated property: has_related_synonym
annotated target: Aminokarbonsaeure
database_cross_reference: ChEBI

Axiom
annotated source: amino acid
annotated property: has_related_synonym
annotated target: Aminosaeure
database_cross_reference: ChEBI

Axiom
annotated source: amino acid
annotated property: has_related_synonym
annotated target: amino acids
database_cross_reference: ChEBI

alpha-amino-acid residue
type: Class
subclass of: amino-acid residue
subclass of: Restriction
  on property: is substituent group from
  some values from: alpha-amino acid
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-amino-acid residues
id: CHEBI:33710
in_subset: 3 STAR

Axiom
annotated source: alpha-amino-acid residue
annotated property: has_related_synonym
annotated target: alpha-amino-acid residues
database_cross_reference: ChEBI

alpha-amino-acid cation
type: Class
subclass of: amino-acid cation

carbohydrate acid
type: Class
subclass of: carbohydrate
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbohydrate acid anion
has_exact_synonym: carbohydrate acid
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate acids
id: CHEBI:33720
in_subset: 3 STAR

Axiom
annotated source: carbohydrate acid
annotated property: has_exact_synonym
annotated target: carbohydrate acid
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid
annotated property: has_related_synonym
annotated target: carbohydrate acids
database_cross_reference: ChEBI

carbohydrate acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbohydrate acid
has_exact_synonym: carbohydrate acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate acid anions
id: CHEBI:33721
in_subset: 3 STAR

Axiom
annotated source: carbohydrate acid anion
annotated property: has_exact_synonym
annotated target: carbohydrate acid anion
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid anion
annotated property: has_related_synonym
annotated target: carbohydrate acid anions
database_cross_reference: ChEBI

chromium group molecular entity
type: Class
subclass of: d-block molecular entity

manganese group molecular entity
type: Class
subclass of: d-block molecular entity

iron group molecular entity
type: Class
subclass of: d-block molecular entity
has_exact_synonym: iron group molecular entity
has_related_synonym: iron group molecular entities

copper group molecular entity
type: Class
subclass of: d-block molecular entity

vanadium group molecular entity
type: Class
subclass of: d-block molecular entity

nickel group molecular entity
type: Class
subclass of: d-block molecular entity

platinum molecular entity
type: Class
subclass of: nickel group molecular entity

titanium group molecular entity
type: Class
subclass of: d-block molecular entity

canonical nucleoside residue
type: Class
subclass of: nucleoside residue
has_obo_namespace: chebi_ontology
has_related_synonym: canonical nucleoside residues
has_related_synonym: common nucleoside residues
has_related_synonym: nucleoside residue
has_related_synonym: standard nucleoside residues
id: CHEBI:33791
in_subset: 3 STAR

Axiom
annotated source: canonical nucleoside residue
annotated property: has_related_synonym
annotated target: canonical nucleoside residues
database_cross_reference: ChEBI

Axiom
annotated source: canonical nucleoside residue
annotated property: has_related_synonym
annotated target: common nucleoside residues
database_cross_reference: CBN

Axiom
annotated source: canonical nucleoside residue
annotated property: has_related_synonym
annotated target: nucleoside residue
database_cross_reference: CBN

Axiom
annotated source: canonical nucleoside residue
annotated property: has_related_synonym
annotated target: standard nucleoside residues
database_cross_reference: ChEBI

canonical ribonucleoside residue
type: Class
subclass of: canonical nucleoside residue
has_obo_namespace: chebi_ontology
has_related_synonym: N
has_related_synonym: Nuc
has_related_synonym: canonical ribonucleoside residues
has_related_synonym: common ribonucleoside residue
has_related_synonym: common ribonucleoside residues
has_related_synonym: standard ribonucleoside residues
id: CHEBI:33792
in_subset: 3 STAR

Axiom
annotated source: canonical ribonucleoside residue
annotated property: has_related_synonym
annotated target: N
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: has_related_synonym
annotated target: Nuc
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: has_related_synonym
annotated target: canonical ribonucleoside residues
database_cross_reference: ChEBI

Axiom
annotated source: canonical ribonucleoside residue
annotated property: has_related_synonym
annotated target: common ribonucleoside residue
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: has_related_synonym
annotated target: common ribonucleoside residues
database_cross_reference: CBN

Axiom
annotated source: canonical ribonucleoside residue
annotated property: has_related_synonym
annotated target: standard ribonucleoside residues
database_cross_reference: ChEBI

canonical deoxyribonucleoside residue
type: Class
subclass of: canonical nucleoside residue
has_obo_namespace: chebi_ontology
has_related_synonym: canonical deoxyribonucleoside residues
has_related_synonym: common 2'-deoxyribonucleoside residue
has_related_synonym: common 2'-deoxyribonucleoside residues
has_related_synonym: dN
has_related_synonym: dNuc
has_related_synonym: standard deoxyribonucleoside residues
id: CHEBI:33793
in_subset: 3 STAR

Axiom
annotated source: canonical deoxyribonucleoside residue
annotated property: has_related_synonym
annotated target: canonical deoxyribonucleoside residues
database_cross_reference: ChEBI

Axiom
annotated source: canonical deoxyribonucleoside residue
annotated property: has_related_synonym
annotated target: common 2'-deoxyribonucleoside residue
database_cross_reference: CBN

Axiom
annotated source: canonical deoxyribonucleoside residue
annotated property: has_related_synonym
annotated target: common 2'-deoxyribonucleoside residues
database_cross_reference: CBN

Axiom
annotated source: canonical deoxyribonucleoside residue
annotated property: has_related_synonym
annotated target: dN
database_cross_reference: CBN

Axiom
annotated source: canonical deoxyribonucleoside residue
annotated property: has_related_synonym
annotated target: dNuc
database_cross_reference: CBN

Axiom
annotated source: canonical deoxyribonucleoside residue
annotated property: has_related_synonym
annotated target: standard deoxyribonucleoside residues
database_cross_reference: ChEBI

organic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: organic molecular entity
definition: An organic compound having at least one hydroxy group attached to a carbon atom.
has_alternative_id: CHEBI:64710
has_exact_synonym: hydroxy compounds
has_obo_namespace: chebi_ontology
has_related_synonym: organic alcohol
has_related_synonym: organic hydroxy compounds
id: CHEBI:33822
in_subset: 3 STAR

Axiom
annotated source: organic hydroxy compound
annotated property: has_exact_synonym
annotated target: hydroxy compounds
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: organic hydroxy compound
annotated property: has_related_synonym
annotated target: organic alcohol
database_cross_reference: ChEBI

Axiom
annotated source: organic hydroxy compound
annotated property: has_related_synonym
annotated target: organic hydroxy compounds
database_cross_reference: ChEBI

organic cyclic compound
type: Class
subclass of: cyclic compound
subclass of: organic molecule
definition: Any organic molecule that consists of atoms connected in the form of a ring.
has_obo_namespace: chebi_ontology
has_related_synonym: organic cyclic compounds
id: CHEBI:33832
in_subset: 3 STAR

Axiom
annotated source: organic cyclic compound
annotated property: has_related_synonym
annotated target: organic cyclic compounds
database_cross_reference: ChEBI

heteroarene
type: Class
subclass of: organic heterocyclic compound
subclass of: organic aromatic compound
definition: A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2).
has_exact_synonym: heteroarenes
has_obo_namespace: chebi_ontology
has_related_synonym: hetarenes
id: CHEBI:33833
in_subset: 3 STAR

Axiom
annotated source: heteroarene
annotated property: has_exact_synonym
annotated target: heteroarenes
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: heteroarene
annotated property: has_related_synonym
annotated target: hetarenes
database_cross_reference: IUPAC

benzenoid aromatic compound
type: Class
subclass of: carbocyclic compound
subclass of: organic aromatic compound

conjugated protein
type: Class
subclass of: protein
definition: Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion.
database_cross_reference: COMe:PRX000001
has_exact_synonym: conjugated proteins
has_obo_namespace: chebi_ontology
has_related_synonym: complex protein
id: CHEBI:33837
in_subset: 3 STAR

Axiom
annotated source: conjugated protein
annotated property: has_exact_synonym
annotated target: conjugated proteins
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: conjugated protein
annotated property: has_related_synonym
annotated target: complex protein
database_cross_reference: COMe

macromolecule
type: Class
subclass of: polyatomic entity
definition: A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
database_cross_reference: Wikipedia:Macromolecule
has_exact_synonym: macromolecule
has_obo_namespace: chebi_ontology
has_related_synonym: macromolecules
has_related_synonym: polymer
has_related_synonym: polymer molecule
has_related_synonym: polymers
id: CHEBI:33839
in_subset: 3 STAR

Axiom
annotated source: macromolecule
annotated property: has_exact_synonym
annotated target: macromolecule
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: macromolecule
annotated property: has_related_synonym
annotated target: macromolecules
database_cross_reference: ChEBI

Axiom
annotated source: macromolecule
annotated property: has_related_synonym
annotated target: polymer
database_cross_reference: ChEBI

Axiom
annotated source: macromolecule
annotated property: has_related_synonym
annotated target: polymer molecule
database_cross_reference: IUPAC

Axiom
annotated source: macromolecule
annotated property: has_related_synonym
annotated target: polymers
database_cross_reference: ChEBI

aromatic annulene
type: Class
subclass of: annulene
subclass of: monocyclic arene

monocyclic arene
type: Class
subclass of: arene

polycyclic arene
type: Class
subclass of: arene
subclass of: polycyclic hydrocarbon

phenols
type: Class
subclass of: organic aromatic compound
subclass of: organic hydroxy compound
definition: Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
charge: 0
formula: C6HOR5
mass: 89.072
monoisotopicmass: 89.00274
smiles: C1(=C(C(=C(C(=C1*)*)*)*)*)O
has_alternative_id: CHEBI:13664
has_alternative_id: CHEBI:13825
has_alternative_id: CHEBI:25969
has_alternative_id: CHEBI:2857
database_cross_reference: KEGG:C15584
database_cross_reference: MetaCyc:Phenols
database_cross_reference: Wikipedia:Phenols
has_exact_synonym: phenols
has_obo_namespace: chebi_ontology
has_related_synonym: Aryl alcohol
has_related_synonym: a phenol
has_related_synonym: arenols
id: CHEBI:33853
in_subset: 3 STAR

Axiom
annotated source: phenols
annotated property: has_exact_synonym
annotated target: phenols
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: phenols
annotated property: has_related_synonym
annotated target: Aryl alcohol
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: phenols
annotated property: has_related_synonym
annotated target: a phenol
database_cross_reference: UniProt

Axiom
annotated source: phenols
annotated property: has_related_synonym
annotated target: arenols
database_cross_reference: IUPAC

transition element coordination entity
type: Class
subclass of: coordination entity
subclass of: transition element molecular entity

reagent
type: Class
subclass of: application
definition: A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
has_exact_synonym: reagent
has_obo_namespace: chebi_ontology
has_related_synonym: reactif
has_related_synonym: reactivo
has_related_synonym: reagents
id: CHEBI:33893
in_subset: 3 STAR

Axiom
annotated source: reagent
annotated property: has_exact_synonym
annotated target: reagent
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: reagent
annotated property: has_related_synonym
annotated target: reactif
database_cross_reference: IUPAC

Axiom
annotated source: reagent
annotated property: has_related_synonym
annotated target: reactivo
database_cross_reference: IUPAC

Axiom
annotated source: reagent
annotated property: has_related_synonym
annotated target: reagents
database_cross_reference: ChEBI

metallotetrapyrrole
type: Class
subclass of: cyclic tetrapyrrole

aldohexose
type: Class
subclass of: aldose
subclass of: hexose
definition: A hexose with a (potential) aldehyde group at one end.
has_alternative_id: CHEBI:2558
has_exact_synonym: aldohexose
has_obo_namespace: chebi_ontology
has_related_synonym: aldohexoses
id: CHEBI:33917
in_subset: 3 STAR

Axiom
annotated source: aldohexose
annotated property: has_exact_synonym
annotated target: aldohexose
database_cross_reference: ChEBI

Axiom
annotated source: aldohexose
annotated property: has_related_synonym
annotated target: aldohexoses
database_cross_reference: ChEBI

macronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
has_obo_namespace: chebi_ontology
has_related_synonym: macronutrients
id: CHEBI:33937
in_subset: 3 STAR

Axiom
annotated source: macronutrient
annotated property: has_related_synonym
annotated target: macronutrients
database_cross_reference: ChEBI

halide salt
type: Class
subclass of: salt
subclass of: halide

gold molecular entity
type: Class
subclass of: copper group molecular entity

elemental gold
type: Class
subclass of: gold molecular entity

magnesium coordination entity
type: Class
subclass of: magnesium molecular entity
subclass of: alkaline earth coordination entity

saxitoxin
type: Class
subclass of: paralytic shellfish toxin
subclass of: carbamate ester

serotonin(1+)
type: Class
subclass of: independent continuant
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: serotonin
definition: An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3.
charge: +1
formula: C10H13N2O
inchi: InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1
inchikey: QZAYGJVTTNCVMB-UHFFFAOYSA-O
mass: 177.22250
monoisotopicmass: 177.10224
smiles: [NH3+]CCc1c[nH]c2ccc(O)cc12
has_exact_synonym: 2-(5-hydroxy-1H-indol-3-yl)ethanaminium
has_obo_namespace: chebi_ontology
has_related_synonym: serotonin
has_related_synonym: serotonin cation
id: CHEBI:350546
in_subset: 3 STAR

Axiom
annotated source: serotonin(1+)
annotated property: has_exact_synonym
annotated target: 2-(5-hydroxy-1H-indol-3-yl)ethanaminium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: serotonin(1+)
annotated property: has_related_synonym
annotated target: serotonin
database_cross_reference: UniProt

Axiom
annotated source: serotonin(1+)
annotated property: has_related_synonym
annotated target: serotonin cation
database_cross_reference: ChEBI

nitrogen hydride
type: Class
subclass of: pnictogen hydride
subclass of: nitrogen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: nitrogen hydrides
id: CHEBI:35106
in_subset: 3 STAR

Axiom
annotated source: nitrogen hydride
annotated property: has_related_synonym
annotated target: nitrogen hydrides
database_cross_reference: ChEBI

azane
type: Class
subclass of: nitrogen hydride
definition: Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
has_obo_namespace: chebi_ontology
has_related_synonym: azanes
id: CHEBI:35107
in_subset: 3 STAR

Axiom
annotated source: azane
annotated property: has_related_synonym
annotated target: azanes
database_cross_reference: ChEBI

aldose phosphate
type: Class
subclass of: phospho sugar

calcium salt
type: Class
subclass of: calcium molecular entity
subclass of: alkaline earth salt

cyclic carotene
type: Class
subclass of: carotene

vanadium(0)
type: Class
subclass of: elemental vanadium

elemental vanadium
type: Class
subclass of: vanadium molecular entity

sulfate salt
type: Class
subclass of: salt
subclass of: sulfates

terpene
type: Class
subclass of: hydrocarbon
subclass of: isoprenoid

tetraterpene
type: Class
subclass of: terpene

surfactant
type: Class
subclass of: emulsifier

nitrogen oxide
type: Class
subclass of: inorganic oxide
subclass of: nitrogen molecular entity

tracer
type: Class
subclass of: application

label
type: Class
subclass of: application

alkaline earth coordination entity
type: Class
subclass of: alkaline earth molecular entity
subclass of: main-group coordination entity

inhibitor
type: Class
subclass of: biological role
definition: A substance that diminishes the rate of a chemical reaction.
has_exact_synonym: inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: inhibidor
has_related_synonym: inhibiteur
has_related_synonym: inhibitors
id: CHEBI:35222
in_subset: 3 STAR

Axiom
annotated source: inhibitor
annotated property: has_exact_synonym
annotated target: inhibitor
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: inhibitor
annotated property: has_related_synonym
annotated target: inhibidor
database_cross_reference: ChEBI

Axiom
annotated source: inhibitor
annotated property: has_related_synonym
annotated target: inhibiteur
database_cross_reference: ChEBI

Axiom
annotated source: inhibitor
annotated property: has_related_synonym
annotated target: inhibitors
database_cross_reference: ChEBI

catalyst
type: Class
subclass of: chemical role
definition: A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
has_exact_synonym: catalyst
has_obo_namespace: chebi_ontology
has_related_synonym: Katalysator
has_related_synonym: catalizador
has_related_synonym: catalyseur
id: CHEBI:35223
in_subset: 3 STAR

Axiom
annotated source: catalyst
annotated property: has_exact_synonym
annotated target: catalyst
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: catalyst
annotated property: has_related_synonym
annotated target: Katalysator
database_cross_reference: ChEBI

Axiom
annotated source: catalyst
annotated property: has_related_synonym
annotated target: catalizador
database_cross_reference: ChEBI

Axiom
annotated source: catalyst
annotated property: has_related_synonym
annotated target: catalyseur
database_cross_reference: ChEBI

fossil fuel
type: Class
subclass of: fuel

amino acid zwitterion
type: Class
subclass of: zwitterion
definition: The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group.
has_exact_synonym: amino acid zwitterion
has_obo_namespace: chebi_ontology
id: CHEBI:35238
in_subset: 3 STAR

Axiom
annotated source: amino acid zwitterion
annotated property: has_exact_synonym
annotated target: amino acid zwitterion
database_cross_reference: ChEBI

quaternary ammonium ion
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonium
definition: A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups.
charge: +1
formula: NR4
mass: 14.00670
monoisotopicmass: 14.00307
smiles: [*][N+]([*])([*])[*]
has_alternative_id: CHEBI:26470
has_alternative_id: CHEBI:8693
database_cross_reference: KEGG:C06703
has_exact_synonym: quaternary ammonium ion
has_obo_namespace: chebi_ontology
has_related_synonym: Quaternary amine
has_related_synonym: a quaternary ammonium
has_related_synonym: quaternary ammonium ions
id: CHEBI:35267
in_subset: 3 STAR

Axiom
annotated source: quaternary ammonium ion
annotated property: has_exact_synonym
annotated target: quaternary ammonium ion
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: quaternary ammonium ion
annotated property: has_related_synonym
annotated target: Quaternary amine
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: quaternary ammonium ion
annotated property: has_related_synonym
annotated target: a quaternary ammonium
database_cross_reference: UniProt

Axiom
annotated source: quaternary ammonium ion
annotated property: has_related_synonym
annotated target: quaternary ammonium ions
database_cross_reference: ChEBI

ammonium ion derivative
type: Class
subclass of: polyatomic cation
subclass of: nitrogen molecular entity
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonium
definition: A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc).
has_obo_namespace: chebi_ontology
has_related_synonym: ammonium ion derivatives
has_related_synonym: azanium ion derivative
has_related_synonym: azanium ion derivatives
id: CHEBI:35274
in_subset: 3 STAR

Axiom
annotated source: ammonium ion derivative
annotated property: has_related_synonym
annotated target: ammonium ion derivatives
database_cross_reference: ChEBI

Axiom
annotated source: ammonium ion derivative
annotated property: has_related_synonym
annotated target: azanium ion derivative
database_cross_reference: ChEBI

Axiom
annotated source: ammonium ion derivative
annotated property: has_related_synonym
annotated target: azanium ion derivatives
database_cross_reference: ChEBI

acylcholine
type: Class
subclass of: quaternary ammonium ion
definition: A choline ester formed from choline and a carboxylic acid.
charge: +1
formula: C6H13NO2R
mass: 131.17290
monoisotopicmass: 131.09463
smiles: C[N+](C)(C)CCOC([*])=O
has_alternative_id: CHEBI:13245
has_alternative_id: CHEBI:22227
has_alternative_id: CHEBI:2463
database_cross_reference: KEGG:C01777
has_obo_namespace: chebi_ontology
has_related_synonym: acylcholines
has_related_synonym: an acylcholine
id: CHEBI:35287
in_subset: 3 STAR

Axiom
annotated source: acylcholine
annotated property: has_related_synonym
annotated target: acylcholines
database_cross_reference: ChEBI

Axiom
annotated source: acylcholine
annotated property: has_related_synonym
annotated target: an acylcholine
database_cross_reference: UniProt

fused compound
type: Class
subclass of: polycyclic compound

carbopolycyclic compound
type: Class
subclass of: carbocyclic compound
subclass of: homopolycyclic compound

homopolycyclic compound
type: Class
subclass of: homocyclic compound
subclass of: polycyclic compound

ortho-fused polycyclic arene
type: Class
subclass of: polycyclic arene
subclass of: ortho-fused polycyclic hydrocarbon

epoxycarotenol
type: Class
subclass of: epoxycarotenoid
subclass of: carotenol

steroid
type: Class
subclass of: lipid
subclass of: organic polycyclic compound
definition: Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.
charge: 0
formula: C19H31R
mass: 259.450
monoisotopicmass: 259.24258
smiles: C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C
has_alternative_id: CHEBI:13687
has_alternative_id: CHEBI:26768
has_alternative_id: CHEBI:9263
database_cross_reference: KEGG:C00377
database_cross_reference: MetaCyc:Steroids
has_exact_synonym: Steroid
has_exact_synonym: steroids
has_obo_namespace: chebi_ontology
has_related_synonym: a steroid
id: CHEBI:35341
in_subset: 3 STAR

Axiom
annotated source: steroid
annotated property: has_exact_synonym
annotated target: Steroid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: steroid
annotated property: has_exact_synonym
annotated target: steroids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: steroid
annotated property: has_related_synonym
annotated target: a steroid
database_cross_reference: UniProt

17beta-hydroxy steroid
type: Class
subclass of: 17-hydroxy steroid

hydroxy steroid
type: Class
subclass of: organic hydroxy compound
subclass of: steroid
has_alternative_id: CHEBI:24748
has_alternative_id: CHEBI:5814
database_cross_reference: KEGG:C02159
has_obo_namespace: chebi_ontology
has_related_synonym: Hydroxysteroid
has_related_synonym: hydroxy steroids
has_related_synonym: hydroxysteroids
id: CHEBI:35350
in_subset: 3 STAR

Axiom
annotated source: hydroxy steroid
annotated property: has_related_synonym
annotated target: Hydroxysteroid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: hydroxy steroid
annotated property: has_related_synonym
annotated target: hydroxy steroids
database_cross_reference: ChEBI

Axiom
annotated source: hydroxy steroid
annotated property: has_related_synonym
annotated target: hydroxysteroids
database_cross_reference: ChEBI

organonitrogen compound
type: Class
subclass of: heteroorganic entity
subclass of: nitrogen molecular entity
definition: Any heteroorganic entity containing at least one carbon-nitrogen bond.
has_exact_synonym: organonitrogen compounds
has_obo_namespace: chebi_ontology
has_related_synonym: organonitrogens
id: CHEBI:35352
in_subset: 3 STAR

Axiom
annotated source: organonitrogen compound
annotated property: has_exact_synonym
annotated target: organonitrogen compounds
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: organonitrogen compound
annotated property: has_related_synonym
annotated target: organonitrogens
database_cross_reference: ChEBI

fatty acid
type: Class
subclass of: lipid
subclass of: monocarboxylic acid

monosaccharide
type: Class
subclass of: carbohydrate
definition: Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group.
has_alternative_id: CHEBI:25407
has_alternative_id: CHEBI:6984
database_cross_reference: KEGG:C06698
has_exact_synonym: Monosaccharide
has_exact_synonym: monosaccharides
has_obo_namespace: chebi_ontology
has_related_synonym: Monosaccharid
has_related_synonym: Monosacharid
has_related_synonym: monosacarido
has_related_synonym: monosacaridos
id: CHEBI:35381
in_subset: 3 STAR

Axiom
annotated source: monosaccharide
annotated property: has_exact_synonym
annotated target: Monosaccharide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: monosaccharide
annotated property: has_exact_synonym
annotated target: monosaccharides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: monosaccharide
annotated property: has_related_synonym
annotated target: Monosaccharid
database_cross_reference: ChEBI

Axiom
annotated source: monosaccharide
annotated property: has_related_synonym
annotated target: Monosacharid
database_cross_reference: ChEBI

Axiom
annotated source: monosaccharide
annotated property: has_related_synonym
annotated target: monosacarido
database_cross_reference: ChEBI

Axiom
annotated source: monosaccharide
annotated property: has_related_synonym
annotated target: monosacaridos
database_cross_reference: IUPAC

chromium oxoanion
type: Class
subclass of: chromium coordination entity
subclass of: transition element oxoanion

chromium coordination entity
type: Class
subclass of: chromium molecular entity
subclass of: transition element coordination entity

chromate(2-)
type: Class
subclass of: chromium oxoanion
subclass of: divalent inorganic anion

transition element oxoanion
type: Class
subclass of: inorganic anion
subclass of: transition element coordination entity
subclass of: oxoanion

oxoanion
type: Class
subclass of: oxide
subclass of: polyatomic anion
definition: An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.
has_alternative_id: CHEBI:33274
has_alternative_id: CHEBI:33436
has_exact_synonym: oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: oxoacid anions
has_related_synonym: oxoanions
id: CHEBI:35406
in_subset: 3 STAR

Axiom
annotated source: oxoanion
annotated property: has_exact_synonym
annotated target: oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: oxoanion
annotated property: has_related_synonym
annotated target: oxoacid anions
database_cross_reference: ChEBI

Axiom
annotated source: oxoanion
annotated property: has_related_synonym
annotated target: oxoanions
database_cross_reference: ChEBI

ortho-fused bicyclic arene
type: Class
subclass of: ortho-fused polycyclic arene
subclass of: ortho-fused bicyclic hydrocarbon

ortho-fused polycyclic hydrocarbon
type: Class
subclass of: ortho-fused compound

ortho-fused bicyclic hydrocarbon
type: Class
subclass of: ortho-fused compound
subclass of: carbobicyclic compound

antiinfective agent
type: Class
subclass of: drug

anti-inflammatory drug
type: Class
subclass of: drug
subclass of: anti-inflammatory agent
definition: A substance that reduces or suppresses inflammation.
has_obo_namespace: chebi_ontology
has_related_synonym: anti-inflammatory drugs
has_related_synonym: antiinflammatory agent
has_related_synonym: antiinflammatory drug
has_related_synonym: antiinflammatory drugs
id: CHEBI:35472
in_subset: 3 STAR

Axiom
annotated source: anti-inflammatory drug
annotated property: has_related_synonym
annotated target: anti-inflammatory drugs
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory drug
annotated property: has_related_synonym
annotated target: antiinflammatory agent
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory drug
annotated property: has_related_synonym
annotated target: antiinflammatory drug
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory drug
annotated property: has_related_synonym
annotated target: antiinflammatory drugs
database_cross_reference: ChEBI

alkali metal salt
type: Class
subclass of: salt
subclass of: alkali metal molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: alkali metal salts
id: CHEBI:35479
in_subset: 3 STAR

Axiom
annotated source: alkali metal salt
annotated property: has_related_synonym
annotated target: alkali metal salts
database_cross_reference: ChEBI

analgesic
type: Class
subclass of: drug
subclass of: pharmacological role

natural product fundamental parent
type: Class
subclass of: organic fundamental parent
has_exact_synonym: natural product fundamental parents
has_obo_namespace: chebi_ontology
id: CHEBI:35507
in_subset: 3 STAR

Axiom
annotated source: natural product fundamental parent
annotated property: has_exact_synonym
annotated target: natural product fundamental parents
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

steroid fundamental parent
type: Class
subclass of: steroid
subclass of: natural product fundamental parent
has_obo_namespace: chebi_ontology
has_related_synonym: steroid fundamental parents
id: CHEBI:35508
in_subset: 3 STAR

Axiom
annotated source: steroid fundamental parent
annotated property: has_related_synonym
annotated target: steroid fundamental parents
database_cross_reference: ChEBI

cholane
type: Class
subclass of: steroid fundamental parent
charge: 0
formula: C24H42
inchi: InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1
inchikey: QSHQKIURKJITMZ-BRPMRXRMSA-N
mass: 330.59028
monoisotopicmass: 330.32865
has_exact_synonym: cholane
has_obo_namespace: chebi_ontology
id: CHEBI:35519
in_subset: 3 STAR

Axiom
annotated source: cholane
annotated property: has_exact_synonym
annotated target: cholane
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

sympathomimetic agent
type: Class
subclass of: adrenergic agent
definition: A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
has_obo_namespace: chebi_ontology
has_related_synonym: sympathomimetic
has_related_synonym: sympathomimetics
id: CHEBI:35524
in_subset: 3 STAR

Axiom
annotated source: sympathomimetic agent
annotated property: has_related_synonym
annotated target: sympathomimetic
database_cross_reference: ChEBI

Axiom
annotated source: sympathomimetic agent
annotated property: has_related_synonym
annotated target: sympathomimetics
database_cross_reference: ChEBI

heterocyclic organic fundamental parent
type: Class
subclass of: organic fundamental parent

cardiovascular drug
type: Class
subclass of: drug
definition: A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
has_obo_namespace: chebi_ontology
has_related_synonym: cardiovascular agent
has_related_synonym: cardiovascular drugs
id: CHEBI:35554
in_subset: 3 STAR

Axiom
annotated source: cardiovascular drug
annotated property: has_related_synonym
annotated target: cardiovascular agent
database_cross_reference: ChEBI

Axiom
annotated source: cardiovascular drug
annotated property: has_related_synonym
annotated target: cardiovascular drugs
database_cross_reference: ChEBI

alpha-adrenergic agonist
type: Class
subclass of: adrenergic agonist
subclass of: alpha-adrenergic drug
definition: An agent that selectively binds to and activates alpha-adrenergic receptors.
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-adrenergic agonists
has_related_synonym: alpha-adrenergic receptor agonist
has_related_synonym: alpha-adrenoceptor agonists
id: CHEBI:35569
in_subset: 3 STAR

Axiom
annotated source: alpha-adrenergic agonist
annotated property: has_related_synonym
annotated target: alpha-adrenergic agonists
database_cross_reference: ChEBI

Axiom
annotated source: alpha-adrenergic agonist
annotated property: has_related_synonym
annotated target: alpha-adrenergic receptor agonist
database_cross_reference: ChEBI

Axiom
annotated source: alpha-adrenergic agonist
annotated property: has_related_synonym
annotated target: alpha-adrenoceptor agonists
database_cross_reference: IUPHAR

carbon oxoanion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: organooxygen compound
definition: A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.
has_exact_synonym: carbon oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: carbon oxoanions
has_related_synonym: oxocarbon anion
has_related_synonym: oxocarbon anions
id: CHEBI:35604
in_subset: 3 STAR

Axiom
annotated source: carbon oxoanion
annotated property: has_exact_synonym
annotated target: carbon oxoanion
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoanion
annotated property: has_related_synonym
annotated target: carbon oxoanions
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoanion
annotated property: has_related_synonym
annotated target: oxocarbon anion
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoanion
annotated property: has_related_synonym
annotated target: oxocarbon anions
database_cross_reference: ChEBI

carbon oxoacid
type: Class
subclass of: oxoacid
subclass of: organooxygen compound
has_obo_namespace: chebi_ontology
has_related_synonym: carbon oxoacids
has_related_synonym: oxoacids of carbon
id: CHEBI:35605
in_subset: 3 STAR

Axiom
annotated source: carbon oxoacid
annotated property: has_related_synonym
annotated target: carbon oxoacids
database_cross_reference: ChEBI

Axiom
annotated source: carbon oxoacid
annotated property: has_related_synonym
annotated target: oxoacids of carbon
database_cross_reference: ChEBI

vasodilator agent
type: Class
subclass of: cardiovascular drug
definition: A drug used to cause dilation of the blood vessels.
has_obo_namespace: chebi_ontology
has_related_synonym: vasodilator
has_related_synonym: vasodilator agents
id: CHEBI:35620
in_subset: 3 STAR

Axiom
annotated source: vasodilator agent
annotated property: has_related_synonym
annotated target: vasodilator
database_cross_reference: ChEBI

Axiom
annotated source: vasodilator agent
annotated property: has_related_synonym
annotated target: vasodilator agents
database_cross_reference: ChEBI

secondary alcohol
type: Class
subclass of: alcohol

dicarboxylic acid
type: Class
subclass of: dicarboxylic acids and O-substituted derivatives
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dicarboxylic acid anion
definition: Any carboxylic acid containing two carboxy groups.
has_alternative_id: CHEBI:23692
has_alternative_id: CHEBI:36172
has_alternative_id: CHEBI:4501
database_cross_reference: KEGG:C02028
has_exact_synonym: Dicarboxylic acid
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboxylic acids
id: CHEBI:35692
in_subset: 3 STAR

Axiom
annotated source: dicarboxylic acid
annotated property: has_exact_synonym
annotated target: Dicarboxylic acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: dicarboxylic acid
annotated property: has_related_synonym
annotated target: dicarboxylic acids
database_cross_reference: ChEBI

dicarboxylic acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: dicarboxylic acid
has_exact_synonym: dicarboxylic acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboxylic acid anions
id: CHEBI:35693
in_subset: 3 STAR

Axiom
annotated source: dicarboxylic acid anion
annotated property: has_exact_synonym
annotated target: dicarboxylic acid anion
database_cross_reference: ChEBI

Axiom
annotated source: dicarboxylic acid anion
annotated property: has_related_synonym
annotated target: dicarboxylic acid anions
database_cross_reference: ChEBI

ester
type: Class
subclass of: organooxygen compound
definition: A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter.
has_alternative_id: CHEBI:23960
has_alternative_id: CHEBI:4859
database_cross_reference: KEGG:C00287
database_cross_reference: Wikipedia:Ester
has_exact_synonym: Ester
has_obo_namespace: chebi_ontology
has_related_synonym: esters
id: CHEBI:35701
in_subset: 3 STAR

Axiom
annotated source: ester
annotated property: has_exact_synonym
annotated target: Ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: ester
annotated property: has_related_synonym
annotated target: esters
database_cross_reference: ChEBI

nitro compound
type: Class
subclass of: nitrogen molecular entity

C-nitro compound
type: Class
subclass of: nitro compound
subclass of: organic molecule

sulfated glycosaminoglycan
type: Class
subclass of: glycosaminoglycan
subclass of: carbohydrate sulfate
has_obo_namespace: chebi_ontology
has_related_synonym: glycosaminoglycan sulfate
has_related_synonym: glycosaminoglycan sulfates
has_related_synonym: sulfated glycosaminoglycans
id: CHEBI:35722
in_subset: 3 STAR

Axiom
annotated source: sulfated glycosaminoglycan
annotated property: has_related_synonym
annotated target: glycosaminoglycan sulfate
database_cross_reference: ChEBI

Axiom
annotated source: sulfated glycosaminoglycan
annotated property: has_related_synonym
annotated target: glycosaminoglycan sulfates
database_cross_reference: ChEBI

Axiom
annotated source: sulfated glycosaminoglycan
annotated property: has_related_synonym
annotated target: sulfated glycosaminoglycans
database_cross_reference: ChEBI

carbohydrate sulfate
type: Class
subclass of: organic sulfate
subclass of: sulfuric ester
subclass of: carbohydrate derivative
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate sulfates
has_related_synonym: carbohydrate sulphates
id: CHEBI:35724
in_subset: 3 STAR

Axiom
annotated source: carbohydrate sulfate
annotated property: has_related_synonym
annotated target: carbohydrate sulfates
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate sulfate
annotated property: has_related_synonym
annotated target: carbohydrate sulphates
database_cross_reference: ChEBI

monocarboxylic acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: monocarboxylic acid
definition: A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.
charge: -1
formula: CO2R
mass: 44.01000
monoisotopicmass: 43.98983
smiles: [O-]C([*])=O
has_alternative_id: CHEBI:13657
has_alternative_id: CHEBI:25382
has_alternative_id: CHEBI:3407
database_cross_reference: KEGG:C00060
has_obo_namespace: chebi_ontology
has_related_synonym: Carboxylate
has_related_synonym: Monocarboxylate
has_related_synonym: a monocarboxylate
has_related_synonym: monocarboxylates
has_related_synonym: monocarboxylic acid anions
id: CHEBI:35757
in_subset: 3 STAR

Axiom
annotated source: monocarboxylic acid anion
annotated property: has_related_synonym
annotated target: Carboxylate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: monocarboxylic acid anion
annotated property: has_related_synonym
annotated target: Monocarboxylate
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: monocarboxylic acid anion
annotated property: has_related_synonym
annotated target: a monocarboxylate
database_cross_reference: UniProt

Axiom
annotated source: monocarboxylic acid anion
annotated property: has_related_synonym
annotated target: monocarboxylates
database_cross_reference: ChEBI

Axiom
annotated source: monocarboxylic acid anion
annotated property: has_related_synonym
annotated target: monocarboxylic acid anions
database_cross_reference: ChEBI

arsenic oxoanion
type: Class
subclass of: arsenic molecular entity
subclass of: pnictogen oxoanion

phosphate ion
type: Class
subclass of: independent continuant
subclass of: phosphorus oxoanion
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: phosphoric acid
definition: A phosphorus oxoanion that is the conjugate base of phosphoric acid.
has_obo_namespace: chebi_ontology
has_related_synonym: Pi
has_related_synonym: phosphate
has_related_synonym: phosphate ions
id: CHEBI:35780
in_subset: 3 STAR

Axiom
annotated source: phosphate ion
annotated property: has_related_synonym
annotated target: Pi
database_cross_reference: ChEBI

Axiom
annotated source: phosphate ion
annotated property: has_related_synonym
annotated target: phosphate
database_cross_reference: ChEBI

Axiom
annotated source: phosphate ion
annotated property: has_related_synonym
annotated target: phosphate ions
database_cross_reference: ChEBI

oxo steroid
type: Class
subclass of: ketone
subclass of: steroid

imidazopyrimidine
type: Class
subclass of: organic heterobicyclic compound
subclass of: heteroarene
subclass of: organonitrogen heterocyclic compound

pnictogen hydride
type: Class
subclass of: inorganic hydride
subclass of: pnictogen molecular entity
has_exact_synonym: pnictogen hydride
has_obo_namespace: chebi_ontology
has_related_synonym: pnictogen hydrides
id: CHEBI:35881
in_subset: 3 STAR

Axiom
annotated source: pnictogen hydride
annotated property: has_exact_synonym
annotated target: pnictogen hydride
database_cross_reference: ChEBI

Axiom
annotated source: pnictogen hydride
annotated property: has_related_synonym
annotated target: pnictogen hydrides
database_cross_reference: ChEBI

neurotransmitter agent
type: Class
subclass of: drug
subclass of: pharmacological role
definition: A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
has_obo_namespace: chebi_ontology
has_related_synonym: neurotransmitter agents
id: CHEBI:35942
in_subset: 3 STAR

Axiom
annotated source: neurotransmitter agent
annotated property: has_related_synonym
annotated target: neurotransmitter agents
database_cross_reference: ChEBI

hydroxy monocarboxylic acid anion
type: Class
subclass of: monocarboxylic acid anion

cholanoid
type: Class
subclass of: steroid
subclass of: Restriction
  on property: has parent hydride
  some values from: cholane
has_alternative_id: CHEBI:22867
has_alternative_id: CHEBI:50419
database_cross_reference: LIPID_MAPS_class:LMST04
has_obo_namespace: chebi_ontology
has_related_synonym: bile acids and derivatives
has_related_synonym: cholanoids
id: CHEBI:36078
in_subset: 3 STAR

Axiom
annotated source: cholanoid
annotated property: database_cross_reference
annotated target: LIPID_MAPS_class:LMST04
source: LIPID MAPS

Axiom
annotated source: cholanoid
annotated property: has_related_synonym
annotated target: bile acids and derivatives
database_cross_reference: LIPID_MAPS

Axiom
annotated source: cholanoid
annotated property: has_related_synonym
annotated target: cholanoids
database_cross_reference: ChEBI

protein
type: Class
subclass of: information biomacromolecule
subclass of: Restriction
  on property: has part
  some values from: protein polypeptide chain
definition: A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome.
has_alternative_id: CHEBI:13677
has_alternative_id: CHEBI:14911
has_exact_synonym: proteins
has_obo_namespace: chebi_ontology
id: CHEBI:36080
in_subset: 3 STAR

Axiom
annotated source: protein
annotated property: has_exact_synonym
annotated target: proteins
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

inorganic chloride
type: Class
subclass of: chloride salt
subclass of: inorganic salt

cyclitol carboxylic acid anion
type: Class
subclass of: monocarboxylic acid anion

bile acid anion
type: Class
subclass of: monocarboxylic acid anion
subclass of: steroid acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: bile acid anions
id: CHEBI:36235
in_subset: 3 STAR

Axiom
annotated source: bile acid anion
annotated property: has_related_synonym
annotated target: bile acid anions
database_cross_reference: ChEBI

cholanic acid
type: Class
subclass of: cholanic acids
definition: A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24.
charge: 0
formula: C24H40O2
inchi: InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1
inchikey: RPKLZQLYODPWTM-KBMWBBLPSA-N
mass: 360.57320
monoisotopicmass: 360.30283
database_cross_reference: CAS:25312-65-6
database_cross_reference: Patent:JP2008069152
database_cross_reference: Reaxys:13246008
has_exact_synonym: cholan-24-oic acid
has_obo_namespace: chebi_ontology
id: CHEBI:36237
in_subset: 3 STAR

Axiom
annotated source: cholanic acid
annotated property: database_cross_reference
annotated target: CAS:25312-65-6
source: ChemIDplus

Axiom
annotated source: cholanic acid
annotated property: database_cross_reference
annotated target: Reaxys:13246008
source: Reaxys

Axiom
annotated source: cholanic acid
annotated property: has_exact_synonym
annotated target: cholan-24-oic acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

5beta-cholanic acid
type: Class
subclass of: cholanic acid
subclass of: 5beta-cholanic acids
charge: 0
formula: C24H40O2
inchi: InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1
inchikey: RPKLZQLYODPWTM-LVVAJZGHSA-N
mass: 360.57320
monoisotopicmass: 360.30283
database_cross_reference: Beilstein:3214794
database_cross_reference: CAS:546-18-9
database_cross_reference: LIPID_MAPS_instance:LMST04010441
has_exact_synonym: 5beta-cholan-24-oic acid
has_exact_synonym: 5beta-cholanic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (5beta)-cholan-24-oic acid
has_related_synonym: (5beta,17beta)-gamma-methylandrostane-17-butanoic acid
has_related_synonym: 5beta-cholanoic acid
has_related_synonym: ursocholanic acid
id: CHEBI:36238
in_subset: 3 STAR

Axiom
annotated source: 5beta-cholanic acid
annotated property: database_cross_reference
annotated target: Beilstein:3214794
source: Beilstein

Axiom
annotated source: 5beta-cholanic acid
annotated property: database_cross_reference
annotated target: CAS:546-18-9
source: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: database_cross_reference
annotated target: LIPID_MAPS_instance:LMST04010441
source: LIPID MAPS

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_exact_synonym
annotated target: 5beta-cholan-24-oic acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_exact_synonym
annotated target: 5beta-cholanic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_related_synonym
annotated target: (5beta)-cholan-24-oic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_related_synonym
annotated target: (5beta,17beta)-gamma-methylandrostane-17-butanoic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_related_synonym
annotated target: 5beta-cholanoic acid
database_cross_reference: ChemIDplus

Axiom
annotated source: 5beta-cholanic acid
annotated property: has_related_synonym
annotated target: ursocholanic acid
database_cross_reference: ChemIDplus

dicarboxylic acid monoester
type: Class
subclass of: dicarboxylic acids and O-substituted derivatives
subclass of: carboxylic ester
subclass of: carboxylic acid

5beta-cholanic acids
type: Class
subclass of: 5beta steroid
subclass of: cholanic acids
subclass of: Restriction
  on property: has parent hydride
  some values from: 5beta-cholane
definition: Members of the class of cholanic acids based on a 5beta-cholane skeleton.
has_obo_namespace: chebi_ontology
id: CHEBI:36248
in_subset: 3 STAR

bile acid salt
type: Class
subclass of: organic salt
subclass of: cholanoid
definition: A salt of a bile acid.
has_obo_namespace: chebi_ontology
has_related_synonym: bile acid salts
id: CHEBI:36277
in_subset: 3 STAR

Axiom
annotated source: bile acid salt
annotated property: has_related_synonym
annotated target: bile acid salts
database_cross_reference: ChEBI

cholanic acids
type: Class
subclass of: cholanoid
subclass of: steroid acid
has_alternative_id: CHEBI:23166
has_alternative_id: CHEBI:23211
has_obo_namespace: chebi_ontology
id: CHEBI:36278
in_subset: 1 STAR

cyclic tetrapyrrole
type: Class
subclass of: tetrapyrrole
subclass of: cyclic polypyrrole

lepton
type: Class
subclass of: fundamental particle
subclass of: fermion
definition: Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin).
has_obo_namespace: chebi_ontology
has_related_synonym: leptons
id: CHEBI:36338
in_subset: 3 STAR

Axiom
annotated source: lepton
annotated property: has_related_synonym
annotated target: leptons
database_cross_reference: ChEBI

baryon
type: Class
subclass of: fermion
subclass of: hadron
definition: Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy).
has_obo_namespace: chebi_ontology
has_related_synonym: baryons
id: CHEBI:36339
in_subset: 3 STAR

Axiom
annotated source: baryon
annotated property: has_related_synonym
annotated target: baryons
database_cross_reference: ChEBI

fermion
type: Class
subclass of: subatomic particle
definition: Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi.
has_exact_synonym: fermion
has_obo_namespace: chebi_ontology
has_related_synonym: fermions
id: CHEBI:36340
in_subset: 3 STAR

Axiom
annotated source: fermion
annotated property: has_exact_synonym
annotated target: fermion
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: fermion
annotated property: has_related_synonym
annotated target: fermions
database_cross_reference: ChEBI

boson
type: Class
subclass of: subatomic particle
definition: Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose.
has_exact_synonym: boson
has_obo_namespace: chebi_ontology
has_related_synonym: bosons
id: CHEBI:36341
in_subset: 3 STAR

Axiom
annotated source: boson
annotated property: has_exact_synonym
annotated target: boson
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: boson
annotated property: has_related_synonym
annotated target: bosons
database_cross_reference: ChEBI

subatomic particle
type: Class
subclass of: material entity
definition: A particle smaller than an atom.
database_cross_reference: Wikipedia:Subatomic_particle
has_obo_namespace: chebi_ontology
has_related_synonym: subatomic particles
id: CHEBI:36342
in_subset: 3 STAR

Axiom
annotated source: subatomic particle
annotated property: has_related_synonym
annotated target: subatomic particles
database_cross_reference: ChEBI

composite particle
type: Class
subclass of: subatomic particle
definition: A subatomic particle known to have substructure (i.e. consisting of smaller particles).
has_obo_namespace: chebi_ontology
has_related_synonym: composite particles
id: CHEBI:36343
in_subset: 3 STAR

Axiom
annotated source: composite particle
annotated property: has_related_synonym
annotated target: composite particles
database_cross_reference: ChEBI

hadron
type: Class
subclass of: composite particle
definition: Hadron is a subatomic particle which experiences the strong force.
has_obo_namespace: chebi_ontology
has_related_synonym: hadrons
id: CHEBI:36344
in_subset: 3 STAR

Axiom
annotated source: hadron
annotated property: has_related_synonym
annotated target: hadrons
database_cross_reference: ChEBI

nuclear particle
type: Class
subclass of: subatomic particle
definition: A nucleus or any of its constituents in any of their energy states.
has_exact_synonym: nuclear particle
has_obo_namespace: chebi_ontology
id: CHEBI:36347
in_subset: 3 STAR

Axiom
annotated source: nuclear particle
annotated property: has_exact_synonym
annotated target: nuclear particle
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

neutrino
type: Class
subclass of: lepton

polyatomic entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: group
definition: Any molecular entity consisting of more than one atom.
has_obo_namespace: chebi_ontology
has_related_synonym: polyatomic entities
id: CHEBI:36357
in_subset: 3 STAR

Axiom
annotated source: polyatomic entity
annotated property: has_related_synonym
annotated target: polyatomic entities
database_cross_reference: ChEBI

polyatomic ion
type: Class
subclass of: ion
subclass of: polyatomic entity
definition: An ion consisting of more than one atom.
has_obo_namespace: chebi_ontology
has_related_synonym: polyatomic ions
id: CHEBI:36358
in_subset: 3 STAR

Axiom
annotated source: polyatomic ion
annotated property: has_related_synonym
annotated target: polyatomic ions
database_cross_reference: ChEBI

phosphorus oxoacid derivative
type: Class
subclass of: oxoacid derivative
subclass of: phosphorus oxoacids and derivatives
subclass of: Restriction
  on property: has functional parent
  some values from: phosphorus oxoacid
has_exact_synonym: phosphorus oxoacid derivative
has_obo_namespace: chebi_ontology
id: CHEBI:36359
in_subset: 3 STAR

Axiom
annotated source: phosphorus oxoacid derivative
annotated property: has_exact_synonym
annotated target: phosphorus oxoacid derivative
database_cross_reference: ChEBI

phosphorus oxoacids and derivatives
type: Class
subclass of: phosphorus molecular entity
has_obo_namespace: chebi_ontology
id: CHEBI:36360
in_subset: 1 STAR

alkaline earth salt
type: Class
subclass of: salt
subclass of: alkaline earth molecular entity

saturated organic heterocyclic parent
type: Class
subclass of: heterocyclic organic fundamental parent

saturated organic heteromonocyclic parent
type: Class
subclass of: organic heteromonocyclic compound
subclass of: saturated organic heterocyclic parent

polycyclic ether
type: Class
subclass of: cyclic ether
subclass of: organic heteropolycyclic compound

main-group coordination entity
type: Class
subclass of: coordination entity
subclass of: main group molecular entity

carbonyl compound
type: Class
subclass of: organic oxo compound
subclass of: organooxygen compound
subclass of: Restriction
  on property: has part
  some values from: carbonyl group
definition: Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.
has_exact_synonym: carbonyl compounds
has_obo_namespace: chebi_ontology
id: CHEBI:36586
in_subset: 3 STAR

Axiom
annotated source: carbonyl compound
annotated property: has_exact_synonym
annotated target: carbonyl compounds
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

organic oxo compound
type: Class
subclass of: organic molecule
subclass of: Restriction
  on property: has part
  some values from: oxo group
definition: Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element.
has_exact_synonym: oxo compounds
has_obo_namespace: chebi_ontology
has_related_synonym: organic oxo compounds
id: CHEBI:36587
in_subset: 3 STAR

Axiom
annotated source: organic oxo compound
annotated property: has_exact_synonym
annotated target: oxo compounds
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: organic oxo compound
annotated property: has_related_synonym
annotated target: organic oxo compounds
database_cross_reference: ChEBI

organochlorine compound
type: Class
subclass of: organohalogen compound
subclass of: chlorine molecular entity

heterotricyclic compound
type: Class
subclass of: heteropolycyclic compound

biladienes
type: Class
subclass of: linear tetrapyrrole
definition: Compounds based on a biladiene skeleton.
has_obo_namespace: chebi_ontology
id: CHEBI:36735
in_subset: 3 STAR

carbobicyclic compound
type: Class
subclass of: bicyclic compound
subclass of: carbopolycyclic compound

monoanion
type: Class
subclass of: anion

17-hydroxy steroid
type: Class
subclass of: hydroxy steroid

inorganic radical
type: Class
subclass of: inorganic molecular entity
subclass of: radical

radical cation
type: Class
subclass of: radical ion
subclass of: cation

radical ion
type: Class
subclass of: ion
subclass of: radical

inorganic radical ion
type: Class
subclass of: inorganic radical
subclass of: radical ion

inorganic radical cation
type: Class
subclass of: radical cation
subclass of: inorganic radical ion

elemental fluorine
type: Class
subclass of: elemental halogen

monoatomic fluorine
type: Class
subclass of: elemental fluorine

chalcogen hydride
type: Class
subclass of: inorganic hydride
subclass of: chalcogen molecular entity
has_exact_synonym: chalcogen hydride
has_obo_namespace: chebi_ontology
has_related_synonym: chalcogen hydrides
id: CHEBI:36902
in_subset: 3 STAR

Axiom
annotated source: chalcogen hydride
annotated property: has_exact_synonym
annotated target: chalcogen hydride
database_cross_reference: ChEBI

Axiom
annotated source: chalcogen hydride
annotated property: has_related_synonym
annotated target: chalcogen hydrides
database_cross_reference: ChEBI

neon molecular entity
type: Class
subclass of: noble gas molecular entity

argon molecular entity
type: Class
subclass of: noble gas molecular entity

krypton molecular entity
type: Class
subclass of: noble gas molecular entity

inorganic ion
type: Class
subclass of: inorganic molecular entity
subclass of: ion
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic ions
id: CHEBI:36914
in_subset: 3 STAR

Axiom
annotated source: inorganic ion
annotated property: has_related_synonym
annotated target: inorganic ions
database_cross_reference: ChEBI

inorganic cation
type: Class
subclass of: inorganic ion
subclass of: cation
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic cations
id: CHEBI:36915
in_subset: 3 STAR

Axiom
annotated source: inorganic cation
annotated property: has_related_synonym
annotated target: inorganic cations
database_cross_reference: ChEBI

cation
type: Class
subclass of: ion
definition: A monoatomic or polyatomic species having one or more elementary charges of the proton.
has_alternative_id: CHEBI:23058
has_alternative_id: CHEBI:3473
database_cross_reference: KEGG:C01373
has_exact_synonym: Cation
has_exact_synonym: cation
has_obo_namespace: chebi_ontology
has_related_synonym: Kation
has_related_synonym: Kationen
has_related_synonym: cationes
has_related_synonym: cations
id: CHEBI:36916
in_subset: 3 STAR

Axiom
annotated source: cation
annotated property: has_exact_synonym
annotated target: Cation
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: cation
annotated property: has_exact_synonym
annotated target: cation
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: has_exact_synonym
annotated target: cation
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: cation
annotated property: has_related_synonym
annotated target: Kation
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: has_related_synonym
annotated target: Kationen
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: has_related_synonym
annotated target: cationes
database_cross_reference: ChEBI

Axiom
annotated source: cation
annotated property: has_related_synonym
annotated target: cations
database_cross_reference: ChEBI

carbon-14 atom
type: Class
subclass of: carbon atom

carbon-13 atom
type: Class
subclass of: carbon atom

nitrogen-15 atom
type: Class
subclass of: nitrogen atom

chalcocarbonic acid
type: Class
subclass of: organochalcogen compound
has_exact_synonym: chalcocarbonic acid
has_exact_synonym: chalcocarbonic acids
has_obo_namespace: chebi_ontology
has_related_synonym: chalcocarbonic acids
id: CHEBI:36961
in_subset: 3 STAR

Axiom
annotated source: chalcocarbonic acid
annotated property: has_exact_synonym
annotated target: chalcocarbonic acid
database_cross_reference: ChEBI

Axiom
annotated source: chalcocarbonic acid
annotated property: has_exact_synonym
annotated target: chalcocarbonic acids
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: chalcocarbonic acid
annotated property: has_related_synonym
annotated target: chalcocarbonic acids
database_cross_reference: ChEBI

organochalcogen compound
type: Class
subclass of: heteroorganic entity
subclass of: chalcogen molecular entity
definition: An organochalcogen compound is a compound containing at least one carbon-chalcogen bond.
has_exact_synonym: organochalcogen compound
has_obo_namespace: chebi_ontology
has_related_synonym: organochalcogen compounds
id: CHEBI:36962
in_subset: 3 STAR

Axiom
annotated source: organochalcogen compound
annotated property: has_exact_synonym
annotated target: organochalcogen compound
database_cross_reference: ChEBI

Axiom
annotated source: organochalcogen compound
annotated property: has_related_synonym
annotated target: organochalcogen compounds
database_cross_reference: ChEBI

organooxygen compound
type: Class
subclass of: oxygen molecular entity
subclass of: organochalcogen compound
definition: An organochalcogen compound containing at least one carbon-oxygen bond.
database_cross_reference: PMID:17586126
has_exact_synonym: organooxygen compound
has_obo_namespace: chebi_ontology
has_related_synonym: organooxygen compounds
id: CHEBI:36963
in_subset: 3 STAR

Axiom
annotated source: organooxygen compound
annotated property: database_cross_reference
annotated target: PMID:17586126
source: Europe PMC

Axiom
annotated source: organooxygen compound
annotated property: has_exact_synonym
annotated target: organooxygen compound
database_cross_reference: ChEBI

Axiom
annotated source: organooxygen compound
annotated property: has_related_synonym
annotated target: organooxygen compounds
database_cross_reference: ChEBI

nucleotide
type: Class
subclass of: nucleoside phosphate

pyridine nucleotide
type: Class
subclass of: pyridines
subclass of: nucleotide

nicotinamide dinucleotide
type: Class
subclass of: nicotinamide nucleotide
subclass of: dinucleotide

ribonucleoside 5'-phosphate
type: Class
subclass of: nucleoside 5'-phosphate
subclass of: ribonucleotide

amino-acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: organonitrogen compound
subclass of: Restriction
  on property: is conjugate base of
  some values from: amino acid
has_exact_synonym: amino-acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: amino acid anions
has_related_synonym: amino-acid anions
id: CHEBI:37022
in_subset: 3 STAR

Axiom
annotated source: amino-acid anion
annotated property: has_exact_synonym
annotated target: amino-acid anion
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid anion
annotated property: has_related_synonym
annotated target: amino acid anions
database_cross_reference: ChEBI

Axiom
annotated source: amino-acid anion
annotated property: has_related_synonym
annotated target: amino-acid anions
database_cross_reference: ChEBI

purine ribonucleoside 5'-triphosphate
type: Class
subclass of: purine ribonucleoside triphosphate
subclass of: purine ribonucleotide
subclass of: ribonucleoside 5'-triphosphate

ribonucleoside 5'-triphosphate
type: Class
subclass of: ribonucleoside 5'-phosphate

adenosine 5'-phosphate
type: Class
subclass of: adenosine phosphate

guanosine 5'-phosphate
type: Class
subclass of: guanosine phosphate

barium molecular entity
type: Class
subclass of: alkaline earth molecular entity

elemental barium
type: Class
subclass of: barium molecular entity

organofluorine compound
type: Class
subclass of: organohalogen compound
subclass of: fluorine molecular entity

glucan
type: Class
subclass of: homopolysaccharide
definition: A polysaccharide composed of glucose residues.
formula: C12H22O11(C6H10O5)n
has_alternative_id: CHEBI:24255
has_alternative_id: CHEBI:5392
database_cross_reference: CAS:9037-91-6
database_cross_reference: KEGG:C01379
has_exact_synonym: Glucan
has_exact_synonym: glucan
has_obo_namespace: chebi_ontology
has_related_synonym: glucans
id: CHEBI:37163
in_subset: 3 STAR

Axiom
annotated source: glucan
annotated property: database_cross_reference
annotated target: CAS:9037-91-6
source: ChemIDplus

Axiom
annotated source: glucan
annotated property: has_exact_synonym
annotated target: Glucan
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glucan
annotated property: has_exact_synonym
annotated target: glucan
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: glucan
annotated property: has_related_synonym
annotated target: glucans
database_cross_reference: ChEBI

homopolysaccharide
type: Class
subclass of: polysaccharide
definition: Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.
has_exact_synonym: homopolysaccharide
has_obo_namespace: chebi_ontology
has_related_synonym: homoglycan
has_related_synonym: homopolysaccharides
id: CHEBI:37164
in_subset: 3 STAR

Axiom
annotated source: homopolysaccharide
annotated property: has_exact_synonym
annotated target: homopolysaccharide
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: homopolysaccharide
annotated property: has_related_synonym
annotated target: homoglycan
database_cross_reference: IUPAC

Axiom
annotated source: homopolysaccharide
annotated property: has_related_synonym
annotated target: homopolysaccharides
database_cross_reference: ChEBI

organic hydride
type: Class
subclass of: hydrides
has_obo_namespace: chebi_ontology
has_related_synonym: organic hydrides
id: CHEBI:37175
in_subset: 3 STAR

Axiom
annotated source: organic hydride
annotated property: has_related_synonym
annotated target: organic hydrides
database_cross_reference: ChEBI

mononuclear parent hydride
type: Class
subclass of: hydrides
has_exact_synonym: mononuclear parent hydrides
has_obo_namespace: chebi_ontology
has_related_synonym: mononuclear hydride
has_related_synonym: mononuclear hydrides
id: CHEBI:37176
in_subset: 3 STAR

Axiom
annotated source: mononuclear parent hydride
annotated property: has_exact_synonym
annotated target: mononuclear parent hydrides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: mononuclear parent hydride
annotated property: has_related_synonym
annotated target: mononuclear hydride
database_cross_reference: ChEBI

Axiom
annotated source: mononuclear parent hydride
annotated property: has_related_synonym
annotated target: mononuclear hydrides
database_cross_reference: IUPAC

silicon coordination entity
type: Class
subclass of: silicon molecular entity
subclass of: main-group coordination entity

silicon oxoanion
type: Class
subclass of: inorganic anion
subclass of: oxoanion
subclass of: silicon coordination entity

elemental lead
type: Class
subclass of: lead molecular entity

titanium molecular entity
type: Class
subclass of: titanium group molecular entity

elemental sodium
type: Class
subclass of: sodium molecular entity
has_obo_namespace: chebi_ontology
id: CHEBI:37246
in_subset: 3 STAR

tropane alkaloid
type: Class
subclass of: alkaloid
subclass of: azabicycloalkane

phosphorus oxide
type: Class
subclass of: phosphorus molecular entity

tetraphosphorus decaoxide
type: Class
subclass of: phosphorus oxide

mucopolysaccharide
type: Class
subclass of: glycosaminoglycan
definition: Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid.
has_alternative_id: CHEBI:25425
has_alternative_id: CHEBI:7011
database_cross_reference: KEGG:C05114
has_exact_synonym: Mucopolysaccharide
has_exact_synonym: mucopolysaccharides
has_obo_namespace: chebi_ontology
has_related_synonym: Mucopolysaccharid
has_related_synonym: Mukopolysaccharid
has_related_synonym: mucopolisacarido
has_related_synonym: mucopolisacaridos
id: CHEBI:37395
in_subset: 3 STAR

Axiom
annotated source: mucopolysaccharide
annotated property: has_exact_synonym
annotated target: Mucopolysaccharide
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: mucopolysaccharide
annotated property: has_exact_synonym
annotated target: mucopolysaccharides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: mucopolysaccharide
annotated property: has_related_synonym
annotated target: Mucopolysaccharid
database_cross_reference: ChEBI

Axiom
annotated source: mucopolysaccharide
annotated property: has_related_synonym
annotated target: Mukopolysaccharid
database_cross_reference: ChEBI

Axiom
annotated source: mucopolysaccharide
annotated property: has_related_synonym
annotated target: mucopolisacarido
database_cross_reference: ChEBI

Axiom
annotated source: mucopolysaccharide
annotated property: has_related_synonym
annotated target: mucopolisacaridos
database_cross_reference: IUPAC

copper coordination entity
type: Class
subclass of: copper molecular entity
subclass of: transition element coordination entity

elemental copper
type: Class
subclass of: copper molecular entity

cyclic ether
type: Class
subclass of: ether
subclass of: oxacycle

acid
type: Class
subclass of: chemical role
definition: An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
has_alternative_id: CHEBI:13800
has_alternative_id: CHEBI:13801
has_alternative_id: CHEBI:22209
has_alternative_id: CHEBI:2426
database_cross_reference: KEGG:C00174
has_exact_synonym: Acid
has_exact_synonym: acid
has_obo_namespace: chebi_ontology
has_related_synonym: Saeure
has_related_synonym: Saeuren
has_related_synonym: acide
has_related_synonym: acido
has_related_synonym: acids
id: CHEBI:37527
in_subset: 3 STAR

Axiom
annotated source: acid
annotated property: has_exact_synonym
annotated target: Acid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acid
annotated property: has_exact_synonym
annotated target: acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: acid
annotated property: has_related_synonym
annotated target: Saeure
database_cross_reference: ChEBI

Axiom
annotated source: acid
annotated property: has_related_synonym
annotated target: Saeuren
database_cross_reference: ChEBI

Axiom
annotated source: acid
annotated property: has_related_synonym
annotated target: acide
database_cross_reference: IUPAC

Axiom
annotated source: acid
annotated property: has_related_synonym
annotated target: acido
database_cross_reference: ChEBI

Axiom
annotated source: acid
annotated property: has_related_synonym
annotated target: acids
database_cross_reference: ChEBI

heteroatomic molecular entity
type: Class
subclass of: polyatomic entity
definition: A molecular entity consisting of two or more chemical elements.
has_obo_namespace: chebi_ontology
has_related_synonym: chemical compound
has_related_synonym: heteroatomic molecular entities
id: CHEBI:37577
in_subset: 3 STAR

Axiom
annotated source: heteroatomic molecular entity
annotated property: has_related_synonym
annotated target: chemical compound
database_cross_reference: ChEBI

Axiom
annotated source: heteroatomic molecular entity
annotated property: has_related_synonym
annotated target: heteroatomic molecular entities
database_cross_reference: ChEBI

halide
type: Class
subclass of: halogen molecular entity
subclass of: heteroatomic molecular entity

allenes
type: Class
subclass of: olefinic compound

carboxamide
type: Class
subclass of: primary amide
subclass of: organonitrogen compound
subclass of: organooxygen compound
subclass of: Restriction
  on property: has part
  some values from: carbamoyl group
definition: An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom.
charge: 0
formula: CNOR3
mass: 42.01680
monoisotopicmass: 41.99799
smiles: [*]C(=O)N([*])[*]
has_alternative_id: CHEBI:35354
has_alternative_id: CHEBI:35355
has_exact_synonym: carboxamides
has_obo_namespace: chebi_ontology
has_related_synonym: carboxamides
has_related_synonym: primary carboxamide
id: CHEBI:37622
in_subset: 3 STAR

Axiom
annotated source: carboxamide
annotated property: has_exact_synonym
annotated target: carboxamides
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carboxamide
annotated property: has_related_synonym
annotated target: carboxamides
database_cross_reference: ChEBI

Axiom
annotated source: carboxamide
annotated property: has_related_synonym
annotated target: primary carboxamide
database_cross_reference: ChEBI

phosphoric ester
type: Class
subclass of: phosphoric acid derivative
subclass of: ester

sulfuric acid derivative
type: Class
subclass of: sulfur oxoacid derivative
subclass of: Restriction
  on property: has functional parent
  some values from: sulfuric acid
has_exact_synonym: sulfuric acid derivative
has_obo_namespace: chebi_ontology
has_related_synonym: sulfuric acid derivatives
id: CHEBI:37826
in_subset: 3 STAR

Axiom
annotated source: sulfuric acid derivative
annotated property: has_exact_synonym
annotated target: sulfuric acid derivative
database_cross_reference: ChEBI

Axiom
annotated source: sulfuric acid derivative
annotated property: has_related_synonym
annotated target: sulfuric acid derivatives
database_cross_reference: ChEBI

carboacyl group
type: Class
subclass of: acyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carboxylic acid
definition: A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid.
has_exact_synonym: carboacyl groups
has_exact_synonym: carboxylic acyl group
has_obo_namespace: chebi_ontology
has_related_synonym: carboxylic acyl groups
id: CHEBI:37838
in_subset: 3 STAR

Axiom
annotated source: carboacyl group
annotated property: has_exact_synonym
annotated target: carboacyl groups
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carboacyl group
annotated property: has_exact_synonym
annotated target: carboxylic acyl group
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carboacyl group
annotated property: has_related_synonym
annotated target: carboxylic acyl groups
database_cross_reference: IUPAC

adrenergic agonist
type: Class
subclass of: adrenergic agent
definition: An agent that selectively binds to and activates adrenergic receptors.
has_obo_namespace: chebi_ontology
has_related_synonym: adrenergic agonists
has_related_synonym: adrenergic receptor agonist
has_related_synonym: adrenoceptor agonists
has_related_synonym: adrenomimetic
has_related_synonym: adrenomimetics
id: CHEBI:37886
in_subset: 3 STAR

Axiom
annotated source: adrenergic agonist
annotated property: has_related_synonym
annotated target: adrenergic agonists
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agonist
annotated property: has_related_synonym
annotated target: adrenergic receptor agonist
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agonist
annotated property: has_related_synonym
annotated target: adrenoceptor agonists
database_cross_reference: IUPHAR

Axiom
annotated source: adrenergic agonist
annotated property: has_related_synonym
annotated target: adrenomimetic
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agonist
annotated property: has_related_synonym
annotated target: adrenomimetics
database_cross_reference: ChEBI

adrenergic agent
type: Class
subclass of: neurotransmitter agent
definition: Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
has_obo_namespace: chebi_ontology
has_related_synonym: adrenergic agents
has_related_synonym: adrenergic drug
has_related_synonym: adrenergic drugs
has_related_synonym: adrenergic neuron agents
has_related_synonym: adrenergics
id: CHEBI:37962
in_subset: 3 STAR

Axiom
annotated source: adrenergic agent
annotated property: has_related_synonym
annotated target: adrenergic agents
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: has_related_synonym
annotated target: adrenergic drug
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: has_related_synonym
annotated target: adrenergic drugs
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: has_related_synonym
annotated target: adrenergic neuron agents
database_cross_reference: ChEBI

Axiom
annotated source: adrenergic agent
annotated property: has_related_synonym
annotated target: adrenergics
database_cross_reference: ChEBI

homopolymer macromolecule
type: Class
subclass of: macromolecule

polypyrrole
type: Class
subclass of: organonitrogen heterocyclic compound
definition: A compound composed of two or more pyrrole units.
database_cross_reference: Beilstein:8538310
has_obo_namespace: chebi_ontology
has_related_synonym: PPys
has_related_synonym: poly(pyrrole)s
has_related_synonym: polypyrroles
id: CHEBI:38077
in_subset: 3 STAR

Axiom
annotated source: polypyrrole
annotated property: database_cross_reference
annotated target: Beilstein:8538310
source: Beilstein

Axiom
annotated source: polypyrrole
annotated property: has_related_synonym
annotated target: PPys
database_cross_reference: ChEBI

Axiom
annotated source: polypyrrole
annotated property: has_related_synonym
annotated target: poly(pyrrole)s
database_cross_reference: ChEBI

Axiom
annotated source: polypyrrole
annotated property: has_related_synonym
annotated target: polypyrroles
database_cross_reference: ChEBI

organonitrogen heterocyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: organonitrogen compound
definition: Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.
has_obo_namespace: chebi_ontology
has_related_synonym: heterocyclic organonitrogen compounds
has_related_synonym: organonitrogen heterocyclic compounds
id: CHEBI:38101
in_subset: 3 STAR

Axiom
annotated source: organonitrogen heterocyclic compound
annotated property: has_related_synonym
annotated target: heterocyclic organonitrogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: organonitrogen heterocyclic compound
annotated property: has_related_synonym
annotated target: organonitrogen heterocyclic compounds
database_cross_reference: ChEBI

oxacycle
type: Class
subclass of: organic heterocyclic compound
subclass of: organooxygen compound

organic heteropolycyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heteropolycyclic compound
has_alternative_id: CHEBI:25429
has_alternative_id: CHEBI:38075
has_obo_namespace: chebi_ontology
has_related_synonym: organic heteropolycyclic compounds
id: CHEBI:38166
in_subset: 3 STAR

Axiom
annotated source: organic heteropolycyclic compound
annotated property: has_related_synonym
annotated target: organic heteropolycyclic compounds
database_cross_reference: ChEBI

polycyclic heteroarene
type: Class
subclass of: heteroarene
has_obo_namespace: chebi_ontology
has_related_synonym: polycyclic heteroarenes
id: CHEBI:38180
in_subset: 3 STAR

Axiom
annotated source: polycyclic heteroarene
annotated property: has_related_synonym
annotated target: polycyclic heteroarenes
database_cross_reference: ChEBI

bacteriochlorophyll
type: Class
subclass of: chlorophyll

chlorophyllide
type: Class
subclass of: chlorophyll

hydrocarbyl anion
type: Class
subclass of: organic anion

magnesium tetrapyrrole
type: Class
subclass of: metallotetrapyrrole
subclass of: magnesium coordination entity

phorbines
type: Class
subclass of: cyclic tetrapyrrole

2-amino-3-hydroxybutanoic acid
type: Class
subclass of: alpha-amino acid

azabicycloalkane
type: Class
subclass of: organic heterobicyclic compound
subclass of: organonitrogen heterocyclic compound

cholinergic drug
type: Class
subclass of: neurotransmitter agent
definition: Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
has_obo_namespace: chebi_ontology
has_related_synonym: cholinergic agent
has_related_synonym: cholinergic drugs
has_related_synonym: cholinomimetic
id: CHEBI:38323
in_subset: 3 STAR

Axiom
annotated source: cholinergic drug
annotated property: has_related_synonym
annotated target: cholinergic agent
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic drug
annotated property: has_related_synonym
annotated target: cholinergic drugs
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic drug
annotated property: has_related_synonym
annotated target: cholinomimetic
database_cross_reference: ChEBI

cholinergic agonist
type: Class
subclass of: cholinergic drug
definition: Any drug that binds to and activates cholinergic receptors.
has_obo_namespace: chebi_ontology
has_related_synonym: acetylcholine agonist
has_related_synonym: acetylcholine agonists
has_related_synonym: acetylcholine receptor agonist
has_related_synonym: cholinergic agonists
has_related_synonym: cholinomimetic
has_related_synonym: cholinomimetics
id: CHEBI:38324
in_subset: 3 STAR

Axiom
annotated source: cholinergic agonist
annotated property: has_related_synonym
annotated target: acetylcholine agonist
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: has_related_synonym
annotated target: acetylcholine agonists
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: has_related_synonym
annotated target: acetylcholine receptor agonist
database_cross_reference: IUPHAR

Axiom
annotated source: cholinergic agonist
annotated property: has_related_synonym
annotated target: cholinergic agonists
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: has_related_synonym
annotated target: cholinomimetic
database_cross_reference: ChEBI

Axiom
annotated source: cholinergic agonist
annotated property: has_related_synonym
annotated target: cholinomimetics
database_cross_reference: ChEBI

muscarinic agonist
type: Class
subclass of: cholinergic agonist
definition: Any drug that binds to and activates a muscarinic cholinergic receptor.
has_obo_namespace: chebi_ontology
has_related_synonym: muscarinic acetylcholine receptor agonist
has_related_synonym: muscarinic agonists
has_related_synonym: muscarinic cholinergic agonist
has_related_synonym: muscarinic cholinergic agonists
id: CHEBI:38325
in_subset: 3 STAR

Axiom
annotated source: muscarinic agonist
annotated property: has_related_synonym
annotated target: muscarinic acetylcholine receptor agonist
database_cross_reference: ChEBI

Axiom
annotated source: muscarinic agonist
annotated property: has_related_synonym
annotated target: muscarinic agonists
database_cross_reference: ChEBI

Axiom
annotated source: muscarinic agonist
annotated property: has_related_synonym
annotated target: muscarinic cholinergic agonist
database_cross_reference: ChEBI

Axiom
annotated source: muscarinic agonist
annotated property: has_related_synonym
annotated target: muscarinic cholinergic agonists
database_cross_reference: ChEBI

methylindole
type: Class
subclass of: indoles

electron-transport chain inhibitor
type: Class
subclass of: pathway inhibitor

respiratory-chain inhibitor
type: Class
subclass of: electron-transport chain inhibitor

aminoalkylindole
type: Class
subclass of: indoles
has_alternative_id: CHEBI:22503
has_alternative_id: CHEBI:24792
has_obo_namespace: chebi_ontology
has_related_synonym: aminoalkylindoles
id: CHEBI:38631
in_subset: 3 STAR

Axiom
annotated source: aminoalkylindole
annotated property: has_related_synonym
annotated target: aminoalkylindoles
database_cross_reference: ChEBI

pyrazolopyrimidine
type: Class
subclass of: organic heterobicyclic compound
subclass of: organonitrogen heterocyclic compound

organic sodium salt
type: Class
subclass of: organic salt
subclass of: sodium salt
has_exact_synonym: organic sodium salt
has_obo_namespace: chebi_ontology
has_related_synonym: organic sodium salts
id: CHEBI:38700
in_subset: 3 STAR

Axiom
annotated source: organic sodium salt
annotated property: has_exact_synonym
annotated target: organic sodium salt
database_cross_reference: ChEBI

Axiom
annotated source: organic sodium salt
annotated property: has_related_synonym
annotated target: organic sodium salts
database_cross_reference: ChEBI

inorganic sodium salt
type: Class
subclass of: inorganic salt
subclass of: sodium salt

carboxylic acid dianion
type: Class
subclass of: carboxylic acid anion
definition: Any dianion containing at least one carboxy group.
has_exact_synonym: carboxylic acid dianion
has_obo_namespace: chebi_ontology
has_related_synonym: carboxylic acid dianions
id: CHEBI:38716
in_subset: 3 STAR

Axiom
annotated source: carboxylic acid dianion
annotated property: has_exact_synonym
annotated target: carboxylic acid dianion
database_cross_reference: ChEBI

Axiom
annotated source: carboxylic acid dianion
annotated property: has_related_synonym
annotated target: carboxylic acid dianions
database_cross_reference: ChEBI

quinolinemonocarboxylate
type: Class
subclass of: monocarboxylic acid anion

anaesthetic
type: Class
subclass of: drug

general anaesthetic
type: Class
subclass of: anaesthetic

inhalation anaesthetic
type: Class
subclass of: general anaesthetic

indole alkaloid
type: Class
subclass of: alkaloid
subclass of: Restriction
  on property: has part
  some values from: indole skeleton
definition: An alkaloid containing an indole skeleton.
has_alternative_id: CHEBI:24795
has_alternative_id: CHEBI:5901
database_cross_reference: KEGG:C06073
database_cross_reference: Wikipedia:Indole_alkaloid
has_exact_synonym: Indole alkaloid
has_obo_namespace: chebi_ontology
has_related_synonym: indole alkaloids
id: CHEBI:38958
in_subset: 3 STAR

Axiom
annotated source: indole alkaloid
annotated property: has_exact_synonym
annotated target: Indole alkaloid
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: indole alkaloid
annotated property: has_related_synonym
annotated target: indole alkaloids
database_cross_reference: ChEBI

methylbenzene
type: Class
subclass of: alkylbenzene

alkylbenzene
type: Class
subclass of: benzenes
subclass of: monocyclic arene

Bronsted acid
type: Class
subclass of: donor
subclass of: acid
definition: A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
has_exact_synonym: Bronsted acid
has_obo_namespace: chebi_ontology
has_related_synonym: Bronsted-Saeure
has_related_synonym: acide de Bronsted
has_related_synonym: donneur d'hydron
has_related_synonym: hydron donor
id: CHEBI:39141
in_subset: 3 STAR

Axiom
annotated source: Bronsted acid
annotated property: has_exact_synonym
annotated target: Bronsted acid
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: Bronsted acid
annotated property: has_related_synonym
annotated target: Bronsted-Saeure
database_cross_reference: ChEBI

Axiom
annotated source: Bronsted acid
annotated property: has_related_synonym
annotated target: acide de Bronsted
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted acid
annotated property: has_related_synonym
annotated target: donneur d'hydron
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted acid
annotated property: has_related_synonym
annotated target: hydron donor
database_cross_reference: IUPAC

Bronsted base
type: Class
subclass of: acceptor
subclass of: base
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
has_exact_synonym: Bronsted base
has_obo_namespace: chebi_ontology
has_related_synonym: Bronsted-Base
has_related_synonym: accepteur d'hydron
has_related_synonym: base de Bronsted
has_related_synonym: hydron acceptor
id: CHEBI:39142
in_subset: 3 STAR

Axiom
annotated source: Bronsted base
annotated property: has_exact_synonym
annotated target: Bronsted base
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: Bronsted base
annotated property: has_related_synonym
annotated target: Bronsted-Base
database_cross_reference: ChEBI

Axiom
annotated source: Bronsted base
annotated property: has_related_synonym
annotated target: accepteur d'hydron
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted base
annotated property: has_related_synonym
annotated target: base de Bronsted
database_cross_reference: IUPAC

Axiom
annotated source: Bronsted base
annotated property: has_related_synonym
annotated target: hydron acceptor
database_cross_reference: IUPAC

Lewis acid
type: Class
subclass of: acceptor
subclass of: acid

Lewis base
type: Class
subclass of: donor
subclass of: base
definition: A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.
has_exact_synonym: Lewis base
has_obo_namespace: chebi_ontology
has_related_synonym: Lewis-Base
has_related_synonym: base de Lewis
has_related_synonym: donneur d'une paire d'electrons
has_related_synonym: electron donor
id: CHEBI:39144
in_subset: 3 STAR

Axiom
annotated source: Lewis base
annotated property: has_exact_synonym
annotated target: Lewis base
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: Lewis base
annotated property: has_related_synonym
annotated target: Lewis-Base
database_cross_reference: ChEBI

Axiom
annotated source: Lewis base
annotated property: has_related_synonym
annotated target: base de Lewis
database_cross_reference: IUPAC

Axiom
annotated source: Lewis base
annotated property: has_related_synonym
annotated target: donneur d'une paire d'electrons
database_cross_reference: ChEBI

Axiom
annotated source: Lewis base
annotated property: has_related_synonym
annotated target: electron donor
database_cross_reference: ChEBI

chloropicrin
type: Class
subclass of: C-nitro compound
subclass of: organochlorine compound
subclass of: one-carbon compound

straight-chain saturated fatty acid
type: Class
subclass of: saturated fatty acid
subclass of: straight-chain fatty acid

buta-1,3-diene
type: Class
subclass of: butadiene

butadiene
type: Class
subclass of: alkadiene

dihydrogenphosphate
type: Class
subclass of: phosphate ion
subclass of: monovalent inorganic anion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogenphosphate
subclass of: Restriction
  on property: is conjugate base of
  some values from: phosphoric acid
definition: A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated.
charge: -1
formula: H2O4P
inchi: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1
inchikey: NBIIXXVUZAFLBC-UHFFFAOYSA-M
mass: 96.98724
monoisotopicmass: 96.96962
smiles: [H]OP([O-])(=O)O[H]
has_alternative_id: CHEBI:29137
has_alternative_id: CHEBI:39739
database_cross_reference: DrugBank:DB02831
database_cross_reference: Gmelin:1999
database_cross_reference: PDBeChem:2HP
has_exact_synonym: dihydrogen(tetraoxidophosphate)(1-)
has_exact_synonym: dihydrogenphosphate
has_exact_synonym: dihydrogentetraoxophosphate(1-)
has_exact_synonym: dihydrogentetraoxophosphate(V)
has_exact_synonym: dihydroxidodioxidophosphate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: DIHYDROGENPHOSPHATE ION
has_related_synonym: H2PO4(-)
has_related_synonym: [PO2(OH)2](-)
id: CHEBI:39745
in_subset: 3 STAR

Axiom
annotated source: dihydrogenphosphate
annotated property: database_cross_reference
annotated target: Gmelin:1999
source: Gmelin

Axiom
annotated source: dihydrogenphosphate
annotated property: has_exact_synonym
annotated target: dihydrogen(tetraoxidophosphate)(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: dihydrogenphosphate
annotated property: has_exact_synonym
annotated target: dihydrogenphosphate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: dihydrogenphosphate
annotated property: has_exact_synonym
annotated target: dihydrogentetraoxophosphate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: dihydrogenphosphate
annotated property: has_exact_synonym
annotated target: dihydrogentetraoxophosphate(V)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: dihydrogenphosphate
annotated property: has_exact_synonym
annotated target: dihydroxidodioxidophosphate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: dihydrogenphosphate
annotated property: has_related_synonym
annotated target: DIHYDROGENPHOSPHATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: dihydrogenphosphate
annotated property: has_related_synonym
annotated target: H2PO4(-)
database_cross_reference: IUPAC

Axiom
annotated source: dihydrogenphosphate
annotated property: has_related_synonym
annotated target: [PO2(OH)2](-)
database_cross_reference: IUPAC

cyclic ketone
type: Class
subclass of: ketone

carbonate
type: Class
subclass of: carbon oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogencarbonate
charge: -2
formula: CO3
inchi: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
inchikey: BVKZGUZCCUSVTD-UHFFFAOYSA-L
mass: 60.00890
monoisotopicmass: 59.98584
smiles: [O-]C([O-])=O
has_alternative_id: CHEBI:29201
has_alternative_id: CHEBI:41605
database_cross_reference: Beilstein:3600898
database_cross_reference: CAS:3812-32-6
database_cross_reference: Gmelin:1559
database_cross_reference: PDBeChem:CO3
has_exact_synonym: carbonate
has_exact_synonym: trioxidocarbonate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: CARBONATE ION
has_related_synonym: CO3(2-)
has_related_synonym: Karbonat
has_related_synonym: [CO3](2-)
id: CHEBI:41609
in_subset: 3 STAR

Axiom
annotated source: carbonate
annotated property: database_cross_reference
annotated target: Beilstein:3600898
source: Beilstein

Axiom
annotated source: carbonate
annotated property: database_cross_reference
annotated target: CAS:3812-32-6
source: ChemIDplus

Axiom
annotated source: carbonate
annotated property: database_cross_reference
annotated target: Gmelin:1559
source: Gmelin

Axiom
annotated source: carbonate
annotated property: has_exact_synonym
annotated target: carbonate
database_cross_reference: IUPAC

Axiom
annotated source: carbonate
annotated property: has_exact_synonym
annotated target: trioxidocarbonate(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carbonate
annotated property: has_related_synonym
annotated target: CARBONATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: carbonate
annotated property: has_related_synonym
annotated target: CO3(2-)
database_cross_reference: ChEBI

Axiom
annotated source: carbonate
annotated property: has_related_synonym
annotated target: Karbonat
database_cross_reference: ChEBI

Axiom
annotated source: carbonate
annotated property: has_related_synonym
annotated target: [CO3](2-)
database_cross_reference: IUPAC

heptane
type: Class
subclass of: volatile organic compound
subclass of: alkane

hydroxy group
type: Class
subclass of: inorganic group
charge: 0
formula: HO
mass: 17.00734
monoisotopicmass: 17.00274
smiles: *O[H]
has_alternative_id: CHEBI:24706
has_alternative_id: CHEBI:43171
database_cross_reference: PDBeChem:OH
has_exact_synonym: HYDROXY GROUP
has_exact_synonym: hydroxy
has_exact_synonym: hydroxy group
has_obo_namespace: chebi_ontology
has_related_synonym: -OH
has_related_synonym: hydroxyl
has_related_synonym: hydroxyl group
id: CHEBI:43176
in_subset: 3 STAR

Axiom
annotated source: hydroxy group
annotated property: has_exact_synonym
annotated target: HYDROXY GROUP
database_cross_reference: PDBeChem

Axiom
annotated source: hydroxy group
annotated property: has_exact_synonym
annotated target: hydroxy
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydroxy group
annotated property: has_exact_synonym
annotated target: hydroxy group
database_cross_reference: UniProt

Axiom
annotated source: hydroxy group
annotated property: has_related_synonym
annotated target: -OH
database_cross_reference: IUPAC

Axiom
annotated source: hydroxy group
annotated property: has_related_synonym
annotated target: hydroxyl
database_cross_reference: ChEBI

Axiom
annotated source: hydroxy group
annotated property: has_related_synonym
annotated target: hydroxyl group
database_cross_reference: ChEBI

hydrogenphosphate
type: Class
subclass of: phosphate ion
subclass of: divalent inorganic anion
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: Saccharomyces cerevisiae metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: phosphate(3-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: dihydrogenphosphate
definition: A phosphate ion that is the conjugate base of dihydrogenphosphate.
charge: -2
formula: HO4P
inchi: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2
inchikey: NBIIXXVUZAFLBC-UHFFFAOYSA-L
mass: 95.97930
monoisotopicmass: 95.96234
smiles: OP([O-])([O-])=O
has_alternative_id: CHEBI:29139
has_alternative_id: CHEBI:43470
database_cross_reference: Gmelin:1998
database_cross_reference: MolBase:1628
database_cross_reference: PDBeChem:PI
database_cross_reference: PDBeChem:PO4
has_exact_synonym: hydrogen(tetraoxidophosphate)(2-)
has_exact_synonym: hydrogenphosphate
has_exact_synonym: hydrogentetraoxophosphate(2-)
has_exact_synonym: hydrogentetraoxophosphate(V)
has_exact_synonym: hydroxidotrioxidophosphate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: HPO4(2-)
has_related_synonym: HYDROGENPHOSPHATE ION
has_related_synonym: INORGANIC PHOSPHATE GROUP
has_related_synonym: [P(OH)O3](2-)
has_related_synonym: [PO3(OH)](2-)
has_related_synonym: hydrogen phosphate
has_related_synonym: phosphate
id: CHEBI:43474
in_subset: 3 STAR

Axiom
annotated source: hydrogenphosphate
annotated property: database_cross_reference
annotated target: Gmelin:1998
source: Gmelin

Axiom
annotated source: hydrogenphosphate
annotated property: has_exact_synonym
annotated target: hydrogen(tetraoxidophosphate)(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogenphosphate
annotated property: has_exact_synonym
annotated target: hydrogenphosphate
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogenphosphate
annotated property: has_exact_synonym
annotated target: hydrogentetraoxophosphate(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogenphosphate
annotated property: has_exact_synonym
annotated target: hydrogentetraoxophosphate(V)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogenphosphate
annotated property: has_exact_synonym
annotated target: hydroxidotrioxidophosphate(2-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogenphosphate
annotated property: has_related_synonym
annotated target: HPO4(2-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogenphosphate
annotated property: has_related_synonym
annotated target: HYDROGENPHOSPHATE ION
database_cross_reference: PDBeChem

Axiom
annotated source: hydrogenphosphate
annotated property: has_related_synonym
annotated target: INORGANIC PHOSPHATE GROUP
database_cross_reference: PDBeChem

Axiom
annotated source: hydrogenphosphate
annotated property: has_related_synonym
annotated target: [P(OH)O3](2-)
database_cross_reference: MolBase

Axiom
annotated source: hydrogenphosphate
annotated property: has_related_synonym
annotated target: [PO3(OH)](2-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogenphosphate
annotated property: has_related_synonym
annotated target: hydrogen phosphate
database_cross_reference: ChEBI

Axiom
annotated source: hydrogenphosphate
annotated property: has_related_synonym
annotated target: phosphate
database_cross_reference: UniProt

peridinin
type: Class
subclass of: epoxycarotenol
subclass of: allenes

hydrogensulfate
type: Class
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: sulfate
subclass of: Restriction
  on property: is conjugate base of
  some values from: sulfuric acid
charge: -1
formula: HO4S
inchi: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1
inchikey: QAOWNCQODCNURD-UHFFFAOYSA-M
mass: 97.07154
monoisotopicmass: 96.96010
smiles: [H]OS([O-])(=O)=O
has_alternative_id: CHEBI:29199
has_alternative_id: CHEBI:45693
database_cross_reference: Gmelin:2121
has_exact_synonym: hydrogen(tetraoxidosulfate)(1-)
has_exact_synonym: hydrogensulfate
has_exact_synonym: hydrogensulfate(1-)
has_exact_synonym: hydrogentetraoxosulfate(1-)
has_exact_synonym: hydrogentetraoxosulfate(VI)
has_exact_synonym: hydroxidotrioxidosulfate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: HSO4(-)
has_related_synonym: HYDROGEN SULFATE
has_related_synonym: [SO3(OH)](-)
id: CHEBI:45696
in_subset: 3 STAR

Axiom
annotated source: hydrogensulfate
annotated property: database_cross_reference
annotated target: Gmelin:2121
source: Gmelin

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogen(tetraoxidosulfate)(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogensulfate
database_cross_reference: IUPAC

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogensulfate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogentetraoxosulfate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydrogentetraoxosulfate(VI)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_exact_synonym
annotated target: hydroxidotrioxidosulfate(1-)
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogensulfate
annotated property: has_related_synonym
annotated target: HSO4(-)
database_cross_reference: IUPAC

Axiom
annotated source: hydrogensulfate
annotated property: has_related_synonym
annotated target: HYDROGEN SULFATE
database_cross_reference: PDBeChem

Axiom
annotated source: hydrogensulfate
annotated property: has_related_synonym
annotated target: [SO3(OH)](-)
database_cross_reference: IUPAC

oxo group
type: Class
subclass of: inorganic group
charge: 0
formula: O
mass: 15.99940
monoisotopicmass: 15.99491
smiles: O=*
has_alternative_id: CHEBI:29353
has_alternative_id: CHEBI:44607
database_cross_reference: PDBeChem:O
has_exact_synonym: OXO GROUP
has_exact_synonym: oxo
has_obo_namespace: chebi_ontology
has_related_synonym: =O
id: CHEBI:46629
in_subset: 3 STAR

Axiom
annotated source: oxo group
annotated property: has_exact_synonym
annotated target: OXO GROUP
database_cross_reference: PDBeChem

Axiom
annotated source: oxo group
annotated property: has_exact_synonym
annotated target: oxo
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: oxo group
annotated property: has_related_synonym
annotated target: =O
database_cross_reference: IUPAC

asbestos
type: Class
subclass of: silicate mineral

mineral
type: Class
subclass of: chemical substance
definition: In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals').
has_exact_synonym: mineral
has_related_synonym: Minerale
has_related_synonym: minerales
has_related_synonym: minerals
has_related_synonym: mineraux

silicate mineral
type: Class
subclass of: mineral

chrysotile
type: Class
subclass of: serpentine asbestos

riebeckite
type: Class
subclass of: silicate mineral

crocidolite asbestos
type: Class
subclass of: riebeckite
subclass of: amphibole asbestos

serpentine mineral
type: Class
subclass of: silicate mineral

tremolite asbestos
type: Class
subclass of: amphibole asbestos

amphibole asbestos
type: Class
subclass of: asbestos

amosite asbestos
type: Class
subclass of: amphibole asbestos
subclass of: gruenerite

gruenerite
type: Class
subclass of: silicate mineral

serpentine asbestos
type: Class
subclass of: asbestos
subclass of: serpentine mineral

anthophyllite
type: Class
subclass of: silicate mineral

anthophyllite asbestos
type: Class
subclass of: amphibole asbestos
subclass of: anthophyllite

actinolite
type: Class
subclass of: silicate mineral

actinolite asbestos
type: Class
subclass of: amphibole asbestos
subclass of: actinolite

sulfide mineral
type: Class
subclass of: sulfide
subclass of: mineral

sulfide salt
type: Class
subclass of: salt

carbonate salt
type: Class
subclass of: carbonates

solvent
type: Class
subclass of: application
subclass of: chemical role
definition: A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
database_cross_reference: Wikipedia:Solvent
has_obo_namespace: chebi_ontology
has_related_synonym: Loesungsmittel
has_related_synonym: solvant
has_related_synonym: solvents
id: CHEBI:46787
in_subset: 3 STAR

Axiom
annotated source: solvent
annotated property: has_related_synonym
annotated target: Loesungsmittel
database_cross_reference: ChEBI

Axiom
annotated source: solvent
annotated property: has_related_synonym
annotated target: solvant
database_cross_reference: ChEBI

Axiom
annotated source: solvent
annotated property: has_related_synonym
annotated target: solvents
database_cross_reference: ChEBI

carboxy group
type: Class
subclass of: organyl group
charge: 0
formula: CHO2
mass: 45.01744
monoisotopicmass: 44.99765
smiles: *C(=O)O
has_alternative_id: CHEBI:23025
has_alternative_id: CHEBI:41420
database_cross_reference: PDBeChem:FMT
has_exact_synonym: CARBOXY GROUP
has_exact_synonym: carboxy
has_obo_namespace: chebi_ontology
has_related_synonym: -C(O)OH
has_related_synonym: -CO2H
has_related_synonym: -COOH
has_related_synonym: carboxyl group
id: CHEBI:46883
in_subset: 3 STAR

Axiom
annotated source: carboxy group
annotated property: has_exact_synonym
annotated target: CARBOXY GROUP
database_cross_reference: PDBeChem

Axiom
annotated source: carboxy group
annotated property: has_exact_synonym
annotated target: carboxy
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: carboxy group
annotated property: has_related_synonym
annotated target: -C(O)OH
database_cross_reference: IUPAC

Axiom
annotated source: carboxy group
annotated property: has_related_synonym
annotated target: -CO2H
database_cross_reference: ChEBI

Axiom
annotated source: carboxy group
annotated property: has_related_synonym
annotated target: -COOH
database_cross_reference: IUPAC

Axiom
annotated source: carboxy group
annotated property: has_related_synonym
annotated target: carboxyl group
database_cross_reference: ChEBI

silicon hydroxide
type: Class
subclass of: silicon molecular entity

dioxane
type: Class
subclass of: saturated organic heteromonocyclic parent
subclass of: dioxanes

dioxanes
type: Class
subclass of: organic heteromonocyclic compound
subclass of: oxacycle

1,4-dioxane
type: Class
subclass of: volatile organic compound
subclass of: dioxane

acetate ester
type: Class
subclass of: carboxylic ester
subclass of: Restriction
  on property: has functional parent
  some values from: acetic acid
definition: Any carboxylic ester where the carboxylic acid component is acetic acid.
charge: 0
formula: C2H3O2R
mass: 59.04400
monoisotopicmass: 59.01330
smiles: CC(=O)O[*]
has_alternative_id: CHEBI:13244
has_alternative_id: CHEBI:13799
has_alternative_id: CHEBI:22189
has_alternative_id: CHEBI:2406
database_cross_reference: KEGG:C01883
database_cross_reference: Wikipedia:Acetate#Esters
has_obo_namespace: chebi_ontology
has_related_synonym: Acetic ester
has_related_synonym: Acetyl ester
has_related_synonym: acetate
has_related_synonym: acetate esters
has_related_synonym: acetates
has_related_synonym: acetyl esters
has_related_synonym: an acetyl ester
id: CHEBI:47622
in_subset: 3 STAR

Axiom
annotated source: acetate ester
annotated property: has_related_synonym
annotated target: Acetic ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetate ester
annotated property: has_related_synonym
annotated target: Acetyl ester
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: acetate ester
annotated property: has_related_synonym
annotated target: acetate
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: has_related_synonym
annotated target: acetate esters
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: has_related_synonym
annotated target: acetates
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: has_related_synonym
annotated target: acetyl esters
database_cross_reference: ChEBI

Axiom
annotated source: acetate ester
annotated property: has_related_synonym
annotated target: an acetyl ester
database_cross_reference: UniProt

3-oxo steroid
type: Class
subclass of: oxo steroid
subclass of: cyclic ketone

indicator
type: Class
subclass of: application

cyclic polypyrrole
type: Class
subclass of: polypyrrole

dinucleotide
type: Class
subclass of: nucleotide

steroid acid
type: Class
subclass of: steroid
subclass of: organic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: steroid acid anion
definition: Any steroid substituted by at least one carboxy group.
has_obo_namespace: chebi_ontology
has_related_synonym: steroid acids
id: CHEBI:47891
in_subset: 3 STAR

Axiom
annotated source: steroid acid
annotated property: has_related_synonym
annotated target: steroid acids
database_cross_reference: ChEBI

alkanesulfonic acid
type: Class
subclass of: organosulfonic acid

3-oxo-Delta(4) steroid
type: Class
subclass of: 3-oxo steroid
subclass of: enone

microcystin
type: Class
subclass of: heterodetic cyclic peptide

nitric acid
type: Class
subclass of: nitrogen oxoacid

nitrobenzenes
type: Class
subclass of: benzenes
subclass of: C-nitro compound

silicate ion
type: Class
subclass of: silicon oxoanion

sulfur oxide
type: Class
subclass of: inorganic oxide
subclass of: sulfur molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: Schwefeloxide
has_related_synonym: oxides of sulfur
has_related_synonym: sulfur oxides
id: CHEBI:48154
in_subset: 3 STAR

Axiom
annotated source: sulfur oxide
annotated property: has_related_synonym
annotated target: Schwefeloxide
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxide
annotated property: has_related_synonym
annotated target: oxides of sulfur
database_cross_reference: ChEBI

Axiom
annotated source: sulfur oxide
annotated property: has_related_synonym
annotated target: sulfur oxides
database_cross_reference: ChEBI

antiseptic drug
type: Class
subclass of: antiinfective agent

disinfectant
type: Class
subclass of: antimicrobial agent

polar solvent
type: Class
subclass of: solvent
definition: A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
has_exact_synonym: polar solvent
has_obo_namespace: chebi_ontology
has_related_synonym: polar solvents
id: CHEBI:48354
in_subset: 3 STAR

Axiom
annotated source: polar solvent
annotated property: has_exact_synonym
annotated target: polar solvent
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: polar solvent
annotated property: has_related_synonym
annotated target: polar solvents
database_cross_reference: ChEBI

protic solvent
type: Class
subclass of: Bronsted acid
subclass of: polar solvent
definition: A polar solvent that is capable of acting as a hydron (proton) donor.
has_exact_synonym: protogenic solvent
has_obo_namespace: chebi_ontology
id: CHEBI:48356
in_subset: 3 STAR

Axiom
annotated source: protic solvent
annotated property: has_exact_synonym
annotated target: protogenic solvent
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

protophilic solvent
type: Class
subclass of: Bronsted base
subclass of: polar solvent

amphiprotic solvent
type: Class
subclass of: protic solvent
subclass of: protophilic solvent

alpha-adrenergic drug
type: Class
subclass of: adrenergic agent
definition: Any drug that acts on an alpha-adrenergic receptor.
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-adrenergic drugs
id: CHEBI:48539
in_subset: 3 STAR

Axiom
annotated source: alpha-adrenergic drug
annotated property: has_related_synonym
annotated target: alpha-adrenergic drugs
database_cross_reference: ChEBI

agonist
type: Class
subclass of: pharmacological role
definition: Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
has_exact_synonym: agonist
has_obo_namespace: chebi_ontology
has_related_synonym: agonista
has_related_synonym: agoniste
has_related_synonym: agonists
id: CHEBI:48705
in_subset: 3 STAR

Axiom
annotated source: agonist
annotated property: has_exact_synonym
annotated target: agonist
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: agonist
annotated property: has_related_synonym
annotated target: agonista
database_cross_reference: ChEBI

Axiom
annotated source: agonist
annotated property: has_related_synonym
annotated target: agoniste
database_cross_reference: ChEBI

Axiom
annotated source: agonist
annotated property: has_related_synonym
annotated target: agonists
database_cross_reference: ChEBI

antagonist
type: Class
subclass of: pharmacological role

aluminosilicate mineral
type: Class
subclass of: silicate mineral

elemental platinum
type: Class
subclass of: platinum molecular entity

aluminium(3+)
type: Class
subclass of: monoatomic trication
subclass of: monoatomic aluminium
subclass of: aluminium cation

argon atom
type: Class
subclass of: noble gas atom
subclass of: p-block element atom

hydrogen atom
type: Class
subclass of: independent continuant
subclass of: inorganic molecular entity
subclass of: nonmetal atom
subclass of: s-block element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
charge: 0
formula: H
inchi: InChI=1S/H
inchikey: YZCKVEUIGOORGS-UHFFFAOYSA-N
mass: 1.00794
monoisotopicmass: 1.00783
smiles: [H]
has_alternative_id: CHEBI:24634
has_alternative_id: CHEBI:49636
database_cross_reference: WebElements:H
has_exact_synonym: hydrogen
has_obo_namespace: chebi_ontology
has_related_synonym: 1H
has_related_synonym: H
has_related_synonym: Wasserstoff
has_related_synonym: hidrogeno
has_related_synonym: hydrogen
has_related_synonym: hydrogene
id: CHEBI:49637
in_subset: 3 STAR

Axiom
annotated source: hydrogen atom
annotated property: has_exact_synonym
annotated target: hydrogen
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: hydrogen atom
annotated property: has_related_synonym
annotated target: 1H
database_cross_reference: IUPAC

Axiom
annotated source: hydrogen atom
annotated property: has_related_synonym
annotated target: H
database_cross_reference: IUPAC

Axiom
annotated source: hydrogen atom
annotated property: has_related_synonym
annotated target: Wasserstoff
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen atom
annotated property: has_related_synonym
annotated target: hidrogeno
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen atom
annotated property: has_related_synonym
annotated target: hydrogen
database_cross_reference: ChEBI

Axiom
annotated source: hydrogen atom
annotated property: has_related_synonym
annotated target: hydrogene
database_cross_reference: ChEBI

praseodymium atom
type: Class
subclass of: lanthanoid atom
subclass of: f-block element atom

uranium(0)
type: Class
subclass of: monoatomic uranium

zinc dichloride
type: Class
subclass of: zinc molecular entity
subclass of: inorganic chloride

elemental krypton
type: Class
subclass of: krypton molecular entity

monoatomic krypton
type: Class
subclass of: monoatomic entity
subclass of: elemental krypton

monoatomic argon
type: Class
subclass of: monoatomic entity
subclass of: elemental argon

elemental argon
type: Class
subclass of: argon molecular entity

argon(.1+)
type: Class
subclass of: inorganic radical cation
subclass of: monoatomic argon

monoatomic neon
type: Class
subclass of: monoatomic entity
subclass of: elemental neon

elemental neon
type: Class
subclass of: neon molecular entity

organic amino compound
type: Class
subclass of: independent continuant
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has role
  some values from: Bronsted base
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonia
definition: A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups.
has_obo_namespace: chebi_ontology
has_related_synonym: organic amino compounds
id: CHEBI:50047
in_subset: 3 STAR

Axiom
annotated source: organic amino compound
annotated property: has_related_synonym
annotated target: organic amino compounds
database_cross_reference: ChEBI

sulfur coordination entity
type: Class
subclass of: sulfur molecular entity

steroid acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: steroid acid
definition: Any anion formed by loss of a proton from a steroid acid.
has_obo_namespace: chebi_ontology
has_related_synonym: steroid acid anions
id: CHEBI:50160
in_subset: 3 STAR

Axiom
annotated source: steroid acid anion
annotated property: has_related_synonym
annotated target: steroid acid anions
database_cross_reference: ChEBI

P450 inhibitor
type: Class
subclass of: EC 1.14.14.1 (unspecific monooxygenase) inhibitor

canonical nucleotide residue
type: Class
subclass of: nucleotide residue
has_obo_namespace: chebi_ontology
has_related_synonym: canonical nucleotide residues
id: CHEBI:50297
in_subset: 3 STAR

Axiom
annotated source: canonical nucleotide residue
annotated property: has_related_synonym
annotated target: canonical nucleotide residues
database_cross_reference: ChEBI

canonical deoxyribonucleotide residue
type: Class
subclass of: canonical nucleotide residue
has_obo_namespace: chebi_ontology
has_related_synonym: canonical deoxyribonucleotide residues
id: CHEBI:50298
in_subset: 3 STAR

Axiom
annotated source: canonical deoxyribonucleotide residue
annotated property: has_related_synonym
annotated target: canonical deoxyribonucleotide residues
database_cross_reference: ChEBI

canonical ribonucleotide residue
type: Class
subclass of: canonical nucleotide residue
has_obo_namespace: chebi_ontology
has_related_synonym: canonical ribonucleotide residues
id: CHEBI:50299
in_subset: 3 STAR

Axiom
annotated source: canonical ribonucleotide residue
annotated property: has_related_synonym
annotated target: canonical ribonucleotide residues
database_cross_reference: ChEBI

onium compound
type: Class
subclass of: heteroatomic molecular entity
has_obo_namespace: chebi_ontology
id: CHEBI:50312
in_subset: 1 STAR

onium cation
type: Class
subclass of: onium compound
definition: Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.
has_exact_synonym: onium cations
has_obo_namespace: chebi_ontology
has_related_synonym: onium cations
has_related_synonym: onium ion
has_related_synonym: onium ions
id: CHEBI:50313
in_subset: 3 STAR

Axiom
annotated source: onium cation
annotated property: has_exact_synonym
annotated target: onium cations
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: onium cation
annotated property: has_related_synonym
annotated target: onium cations
database_cross_reference: ChEBI

Axiom
annotated source: onium cation
annotated property: has_related_synonym
annotated target: onium ion
database_cross_reference: ChEBI

Axiom
annotated source: onium cation
annotated property: has_related_synonym
annotated target: onium ions
database_cross_reference: ChEBI

nucleotide residue
type: Class
subclass of: organic group
has_obo_namespace: chebi_ontology
has_related_synonym: nucleotide residues
id: CHEBI:50319
in_subset: 3 STAR

Axiom
annotated source: nucleotide residue
annotated property: has_related_synonym
annotated target: nucleotide residues
database_cross_reference: ChEBI

nucleoside residue
type: Class
subclass of: organic group
has_obo_namespace: chebi_ontology
has_related_synonym: nucleoside residues
id: CHEBI:50320
in_subset: 3 STAR

Axiom
annotated source: nucleoside residue
annotated property: has_related_synonym
annotated target: nucleoside residues
database_cross_reference: ChEBI

proteinogenic amino-acid side-chain group
type: Class
subclass of: organyl group

organic nitrogen anion
type: Class
subclass of: organic anion
subclass of: organonitrogen compound

androstanoid
type: Class
subclass of: steroid

probe
type: Class
subclass of: application

vasoconstrictor agent
type: Class
subclass of: cardiovascular drug
definition: Drug used to cause constriction of the blood vessels.
has_obo_namespace: chebi_ontology
id: CHEBI:50514
in_subset: 3 STAR

monoatomic uranium
type: Class
subclass of: elemental uranium

elemental uranium
type: Class
subclass of: uranium molecular entity

alkyl alcohol
type: Class
subclass of: aliphatic alcohol

carbon nanotube
type: Class
subclass of: nanotube
subclass of: carbon nanostructure

nanostructure
type: Class
subclass of: polyatomic entity

nanotube
type: Class
subclass of: nanostructure

carbon nanostructure
type: Class
subclass of: elemental carbon
subclass of: nanostructure

iron oxide
type: Class
subclass of: iron molecular entity

organic molecular entity
type: Class
subclass of: carbon group molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon atom
definition: Any molecular entity that contains carbon.
has_alternative_id: CHEBI:25700
has_alternative_id: CHEBI:33244
has_obo_namespace: chebi_ontology
has_related_synonym: organic compounds
has_related_synonym: organic entity
has_related_synonym: organic molecular entities
id: CHEBI:50860
in_subset: 3 STAR

Axiom
annotated source: organic molecular entity
annotated property: has_related_synonym
annotated target: organic compounds
database_cross_reference: ChEBI

Axiom
annotated source: organic molecular entity
annotated property: has_related_synonym
annotated target: organic entity
database_cross_reference: ChEBI

Axiom
annotated source: organic molecular entity
annotated property: has_related_synonym
annotated target: organic molecular entities
database_cross_reference: ChEBI

genotoxin
type: Class
subclass of: aetiopathogenetic role

allergen
type: Class
subclass of: aetiopathogenetic role

role
type: Class
subclass of: PATO_0000001
definition: A role is particular behaviour which a material entity may exhibit.
has_obo_namespace: chebi_ontology
id: CHEBI:50906
in_subset: 3 STAR

neurotoxin
type: Class
subclass of: aetiopathogenetic role
subclass of: poison
definition: A poison that interferes with the functions of the nervous system.
has_alternative_id: CHEBI:50911
database_cross_reference: Wikipedia:Neurotoxin
has_obo_namespace: chebi_ontology
has_related_synonym: agente neurotoxico
has_related_synonym: nerve poison
has_related_synonym: nerve poisons
has_related_synonym: neurotoxic agent
has_related_synonym: neurotoxic agents
has_related_synonym: neurotoxicant
has_related_synonym: neurotoxins
id: CHEBI:50910
in_subset: 3 STAR

Axiom
annotated source: neurotoxin
annotated property: has_related_synonym
annotated target: agente neurotoxico
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: has_related_synonym
annotated target: nerve poison
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: has_related_synonym
annotated target: nerve poisons
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: has_related_synonym
annotated target: neurotoxic agent
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: has_related_synonym
annotated target: neurotoxic agents
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: has_related_synonym
annotated target: neurotoxicant
database_cross_reference: ChEBI

Axiom
annotated source: neurotoxin
annotated property: has_related_synonym
annotated target: neurotoxins
database_cross_reference: ChEBI

primary amino compound
type: Class
subclass of: organic amino compound
subclass of: Restriction
  on property: is conjugate base of
  some values from: primary ammonium ion
definition: A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group.
has_obo_namespace: chebi_ontology
has_related_synonym: primary amino compounds
id: CHEBI:50994
in_subset: 3 STAR

Axiom
annotated source: primary amino compound
annotated property: has_related_synonym
annotated target: primary amino compounds
database_cross_reference: ChEBI

tertiary amino compound
type: Class
subclass of: organic amino compound

nitrate salt
type: Class
subclass of: salt

inorganic nitrate salt
type: Class
subclass of: inorganic salt
subclass of: nitrate salt

chemical role
type: Class
subclass of: realizable
subclass of: role
subclass of: PATO_0000001
definition: A role played by the molecular entity or part thereof within a chemical context.
has_obo_namespace: chebi_ontology
id: CHEBI:51086
in_subset: 3 STAR

nitrohydrocarbon
type: Class
subclass of: C-nitro compound

nitroarene
type: Class
subclass of: nitrohydrocarbon

nitrogen molecular entity
type: Class
subclass of: pnictogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: nitrogen atom
has_alternative_id: CHEBI:25556
has_alternative_id: CHEBI:7594
database_cross_reference: KEGG:C06061
has_obo_namespace: chebi_ontology
has_related_synonym: Nitrogenous compounds
has_related_synonym: nitrogen compounds
has_related_synonym: nitrogen molecular entities
id: CHEBI:51143
in_subset: 3 STAR

Axiom
annotated source: nitrogen molecular entity
annotated property: has_related_synonym
annotated target: Nitrogenous compounds
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: nitrogen molecular entity
annotated property: has_related_synonym
annotated target: nitrogen compounds
database_cross_reference: ChEBI

Axiom
annotated source: nitrogen molecular entity
annotated property: has_related_synonym
annotated target: nitrogen molecular entities
database_cross_reference: ChEBI

dipolar compound
type: Class
subclass of: organic molecule
definition: An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case.
has_obo_namespace: chebi_ontology
has_related_synonym: dipolar compounds
id: CHEBI:51151
in_subset: 3 STAR

Axiom
annotated source: dipolar compound
annotated property: has_related_synonym
annotated target: dipolar compounds
database_cross_reference: ChEBI

organodiyl group
type: Class
subclass of: organic divalent group
definition: Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s).
has_obo_namespace: chebi_ontology
has_related_synonym: organodiyl groups
id: CHEBI:51422
in_subset: 3 STAR

Axiom
annotated source: organodiyl group
annotated property: has_related_synonym
annotated target: organodiyl groups
database_cross_reference: ChEBI

organic divalent group
type: Class
subclass of: organic group
has_obo_namespace: chebi_ontology
id: CHEBI:51446
in_subset: 1 STAR

organic univalent group
type: Class
subclass of: organic group
has_obo_namespace: chebi_ontology
id: CHEBI:51447
in_subset: 1 STAR

phthalocyanines
type: Class
subclass of: cyclic tetrapyrrole

metallophthalocyanines
type: Class
subclass of: metallotetrapyrrole
subclass of: phthalocyanines

metallophthalocyanine
type: Class
subclass of: metallophthalocyanines

enal
type: Class
subclass of: alpha,beta-unsaturated aldehyde
subclass of: olefinic compound

enone
type: Class
subclass of: alpha,beta-unsaturated ketone
subclass of: olefinic compound

alpha,beta-unsaturated aldehyde
type: Class
subclass of: aldehyde

alpha,beta-unsaturated ketone
type: Class
subclass of: ketone

fucoxanthin
type: Class
subclass of: tertiary alcohol
subclass of: epoxycarotenol
subclass of: secondary alcohol
subclass of: allenes
subclass of: acetate ester

organic polycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: organic cyclic compound
has_obo_namespace: chebi_ontology
has_related_synonym: organic polycyclic compounds
id: CHEBI:51958
in_subset: 3 STAR

Axiom
annotated source: organic polycyclic compound
annotated property: has_related_synonym
annotated target: organic polycyclic compounds
database_cross_reference: ChEBI

organic tricyclic compound
type: Class
subclass of: organic polycyclic compound

biochemical role
type: Class
subclass of: biological role
definition: A biological role played by the molecular entity or part thereof within a biochemical context.
has_obo_namespace: chebi_ontology
id: CHEBI:52206
in_subset: 3 STAR

biophysical role
type: Class
subclass of: biological role

aetiopathogenetic role
type: Class
subclass of: biological role
definition: A role played by the molecular entity or part thereof which causes the development of a pathological process.
has_obo_namespace: chebi_ontology
has_related_synonym: etiopathogenetic agent
has_related_synonym: etiopathogenetic role
id: CHEBI:52209
in_subset: 3 STAR

Axiom
annotated source: aetiopathogenetic role
annotated property: has_related_synonym
annotated target: etiopathogenetic agent
database_cross_reference: ChEBI

Axiom
annotated source: aetiopathogenetic role
annotated property: has_related_synonym
annotated target: etiopathogenetic role
database_cross_reference: ChEBI

pharmacological role
type: Class
subclass of: biological role
definition: A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.
has_obo_namespace: chebi_ontology
id: CHEBI:52210
in_subset: 3 STAR

physiological role
type: Class
subclass of: biological role
has_obo_namespace: chebi_ontology
id: CHEBI:52211
in_subset: 1 STAR

ligand
type: Class
subclass of: chemical role

pharmaceutical
type: Class
subclass of: application
definition: Any substance introduced into a living organism with therapeutic or diagnostic purpose.
has_alternative_id: CHEBI:33293
has_alternative_id: CHEBI:33294
has_obo_namespace: chebi_ontology
has_related_synonym: farmaco
has_related_synonym: medicament
has_related_synonym: pharmaceuticals
id: CHEBI:52217
in_subset: 3 STAR

Axiom
annotated source: pharmaceutical
annotated property: has_related_synonym
annotated target: farmaco
database_cross_reference: ChEBI

Axiom
annotated source: pharmaceutical
annotated property: has_related_synonym
annotated target: medicament
database_cross_reference: ChEBI

Axiom
annotated source: pharmaceutical
annotated property: has_related_synonym
annotated target: pharmaceuticals
database_cross_reference: ChEBI

inorganic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: inorganic molecular entity

cyclic organic group
type: Class
subclass of: organic group
definition: An organic group that consists of a closed ring. It may be a substituent or a skeleton.
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic organic groups
id: CHEBI:52845
in_subset: 3 STAR

Axiom
annotated source: cyclic organic group
annotated property: has_related_synonym
annotated target: cyclic organic groups
database_cross_reference: ChEBI

epitope
type: Class
subclass of: biological role
definition: The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.
has_obo_namespace: chebi_ontology
has_related_synonym: antigenic determinant
has_related_synonym: epitope function
has_related_synonym: epitope role
id: CHEBI:53000
in_subset: 3 STAR

Axiom
annotated source: epitope
annotated property: has_related_synonym
annotated target: antigenic determinant
database_cross_reference: ChEBI

Axiom
annotated source: epitope
annotated property: has_related_synonym
annotated target: epitope function
database_cross_reference: ChEBI

Axiom
annotated source: epitope
annotated property: has_related_synonym
annotated target: epitope role
database_cross_reference: ChEBI

poly(alkylene) macromolecule
type: Class
subclass of: homopolymer macromolecule

polyethylene macromolecule
type: Class
subclass of: poly(alkylene) macromolecule

vinyl polymer macromolecule
type: Class
subclass of: polyethylene macromolecule

poly(vinyl chloride)
type: Class
subclass of: vinyl polymer macromolecule
in_subset: envoPlastics

polyanionic macromolecule
type: Class
subclass of: ionic macromolecule
definition: A polymer carrying multiple negative charges.
has_obo_namespace: chebi_ontology
has_related_synonym: polyanion
has_related_synonym: polyanions
id: CHEBI:53309
in_subset: 3 STAR

Axiom
annotated source: polyanionic macromolecule
annotated property: has_related_synonym
annotated target: polyanion
database_cross_reference: ChEBI

Axiom
annotated source: polyanionic macromolecule
annotated property: has_related_synonym
annotated target: polyanions
database_cross_reference: SUBMITTER

copolymer macromolecule
type: Class
subclass of: macromolecule

ionic macromolecule
type: Class
subclass of: macromolecule
definition: A macromolecule containing ionic groups.
has_obo_namespace: chebi_ontology
has_related_synonym: ionic polymer
has_related_synonym: polyionic macromolecule
id: CHEBI:53368
in_subset: 3 STAR

Axiom
annotated source: ionic macromolecule
annotated property: has_related_synonym
annotated target: ionic polymer
database_cross_reference: ChEBI

Axiom
annotated source: ionic macromolecule
annotated property: has_related_synonym
annotated target: polyionic macromolecule
database_cross_reference: ChEBI

poly(hydroxyalkanoate)
type: Class
subclass of: polyester macromolecule

poly(hydroxybutyrate)
type: Class
subclass of: poly(hydroxyalkanoate)

methyl cellulose
type: Class
subclass of: beta-D-glucan

poly(propylene)
type: Class
subclass of: polyethylene macromolecule
in_subset: envoPlastics

glucagon
type: Class
subclass of: peptide hormone
definition: A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.
charge: 0
formula: C153H225N43O49S
inchikey: MASNOZXLGMXCHN-ZLPAWPGGSA-N
mass: 3482.74700
monoisotopicmass: 3480.61570
database_cross_reference: CAS:16941-32-5
database_cross_reference: CAS:9007-92-5
database_cross_reference: DrugBank:DB00040
database_cross_reference: Drug_Central:2994
database_cross_reference: KEGG:C01501
database_cross_reference: KEGG:D00116
database_cross_reference: PMID:21940356
database_cross_reference: PMID:22014161
database_cross_reference: PMID:22154917
database_cross_reference: PMID:22166985
database_cross_reference: PMID:22167521
database_cross_reference: PMID:22214853
database_cross_reference: PMID:22227186
database_cross_reference: PMID:22286080
database_cross_reference: PMID:22294753
database_cross_reference: PMID:22318544
database_cross_reference: PMID:22334714
database_cross_reference: PMID:22399501
database_cross_reference: PMID:22438981
database_cross_reference: PMID:22454291
database_cross_reference: Reaxys:13191924
database_cross_reference: Wikipedia:Glucagon
has_exact_synonym: Glucagon
has_exact_synonym: L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine
has_obo_namespace: chebi_ontology
has_related_synonym: Glucagone
has_related_synonym: HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
has_related_synonym: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
has_related_synonym: His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr
has_related_synonym: glucagon
has_related_synonym: glucagonum
id: CHEBI:5391
in_subset: 3 STAR

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: CAS:16941-32-5
source: ChemIDplus

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: CAS:9007-92-5
source: ChemIDplus

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: CAS:9007-92-5
source: KEGG COMPOUND

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: Drug_Central:2994
source: DrugCentral

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:21940356
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22014161
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22154917
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22166985
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22167521
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22214853
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22227186
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22286080
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22294753
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22318544
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22334714
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22399501
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22438981
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: PMID:22454291
source: Europe PMC

Axiom
annotated source: glucagon
annotated property: database_cross_reference
annotated target: Reaxys:13191924
source: Reaxys

Axiom
annotated source: glucagon
annotated property: has_exact_synonym
annotated target: Glucagon
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: glucagon
annotated property: has_exact_synonym
annotated target: L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: glucagon
annotated property: has_related_synonym
annotated target: Glucagone
database_cross_reference: ChemIDplus

Axiom
annotated source: glucagon
annotated property: has_related_synonym
annotated target: HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
database_cross_reference: ChEBI

Axiom
annotated source: glucagon
annotated property: has_related_synonym
annotated target: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
database_cross_reference: ChEBI

Axiom
annotated source: glucagon
annotated property: has_related_synonym
annotated target: His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr
database_cross_reference: ChemIDplus

Axiom
annotated source: glucagon
annotated property: has_related_synonym
annotated target: glucagon
database_cross_reference: ChemIDplus
has_synonym_type: INN

Axiom
annotated source: glucagon
annotated property: has_related_synonym
annotated target: glucagonum
database_cross_reference: ChemIDplus
has_synonym_type: INN

heterocyclic compound
type: Class
subclass of: cyclic compound
definition: A cyclic compound having as ring members atoms of at least two different elements.
has_exact_synonym: Heterocyclic compound
has_obo_namespace: chebi_ontology
has_related_synonym: compuesto heterociclico
has_related_synonym: compuestos heterociclicos
has_related_synonym: heterocycle
has_related_synonym: heterocyclic compounds
id: CHEBI:5686
in_subset: 3 STAR

Axiom
annotated source: heterocyclic compound
annotated property: has_exact_synonym
annotated target: Heterocyclic compound
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: heterocyclic compound
annotated property: has_related_synonym
annotated target: compuesto heterociclico
database_cross_reference: IUPAC

Axiom
annotated source: heterocyclic compound
annotated property: has_related_synonym
annotated target: compuestos heterociclicos
database_cross_reference: IUPAC

Axiom
annotated source: heterocyclic compound
annotated property: has_related_synonym
annotated target: heterocycle
database_cross_reference: ChEBI

Axiom
annotated source: heterocyclic compound
annotated property: has_related_synonym
annotated target: heterocyclic compounds
database_cross_reference: ChEBI

tryptaminium
type: Class
subclass of: independent continuant
subclass of: primary ammonium ion
subclass of: Restriction
  on property: has role
  some values from: mouse metabolite
subclass of: Restriction
  on property: has role
  some values from: plant metabolite
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tryptamine
definition: An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3.
charge: +1
formula: C10H13N2
inchi: InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1
inchikey: APJYDQYYACXCRM-UHFFFAOYSA-O
mass: 161.22310
monoisotopicmass: 161.10732
smiles: [NH3+]CCc1c[nH]c2ccccc12
database_cross_reference: Gmelin:533978
has_exact_synonym: 2-(1H-indol-3-yl)ethanaminium
has_obo_namespace: chebi_ontology
has_related_synonym: tryptamine
has_related_synonym: tryptaminium cation
has_related_synonym: tryptaminium(1+)
id: CHEBI:57887
in_subset: 3 STAR

Axiom
annotated source: tryptaminium
annotated property: database_cross_reference
annotated target: Gmelin:533978
source: Gmelin

Axiom
annotated source: tryptaminium
annotated property: has_exact_synonym
annotated target: 2-(1H-indol-3-yl)ethanaminium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: tryptaminium
annotated property: has_related_synonym
annotated target: tryptamine
database_cross_reference: UniProt

Axiom
annotated source: tryptaminium
annotated property: has_related_synonym
annotated target: tryptaminium cation
database_cross_reference: ChEBI

Axiom
annotated source: tryptaminium
annotated property: has_related_synonym
annotated target: tryptaminium(1+)
database_cross_reference: ChEBI

bilirubin(2-)
type: Class
subclass of: independent continuant
subclass of: dicarboxylic acid dianion
subclass of: linear tetrapyrrole anion
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: bilirubin IXalpha
definition: A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3.
charge: -2
formula: C33H34N4O6
inchi: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-
inchikey: BPYKTIZUTYGOLE-IFADSCNNSA-L
mass: 582.64630
monoisotopicmass: 582.24893
database_cross_reference: Beilstein:4083310
has_obo_namespace: chebi_ontology
has_related_synonym: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate
has_related_synonym: bilirubin IXalpha
has_related_synonym: bilirubin dianion
id: CHEBI:57977
in_subset: 3 STAR

Axiom
annotated source: bilirubin(2-)
annotated property: database_cross_reference
annotated target: Beilstein:4083310
source: Beilstein

Axiom
annotated source: bilirubin(2-)
annotated property: has_related_synonym
annotated target: 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate
database_cross_reference: ChEBI

Axiom
annotated source: bilirubin(2-)
annotated property: has_related_synonym
annotated target: bilirubin IXalpha
database_cross_reference: UniProt

Axiom
annotated source: bilirubin(2-)
annotated property: has_related_synonym
annotated target: bilirubin dianion
database_cross_reference: ChEBI

carbon monoxide(1+)
type: Class
subclass of: organic cation

chlorophyll a(1-)
type: Class
subclass of: chlorophyll(1-)

kynurenate
type: Class
subclass of: quinolinemonocarboxylate

cyclic tetrapyrrole anion
type: Class
subclass of: organic anion

very long-chain fatty acid anion
type: Class
subclass of: fatty acid anion

saturated fatty acid anion
type: Class
subclass of: fatty acid anion

straight-chain saturated fatty acid anion
type: Class
subclass of: saturated fatty acid anion

organosulfate oxoanion
type: Class
subclass of: organic anion
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: has functional parent
  some values from: sulfate
subclass of: Restriction
  on property: is conjugate base of
  some values from: organic sulfate
definition: An organic anion of general formula RS(=O)2O(-) where R is an organyl group.
charge: -1
formula: O4SR
mass: 96.06300
monoisotopicmass: 95.95173
smiles: [O-]S(=O)(=O)O[*]
has_obo_namespace: chebi_ontology
has_related_synonym: organosulfate oxoanions
id: CHEBI:58958
in_subset: 3 STAR

Axiom
annotated source: organosulfate oxoanion
annotated property: has_related_synonym
annotated target: organosulfate oxoanions
database_cross_reference: ChEBI

biomarker
type: Class
subclass of: indicator

straight-chain fatty acid
type: Class
subclass of: fatty acid

linear tetrapyrrole anion
type: Class
subclass of: organic anion
definition: An organic anion arising from deprotonation of a acyclic tetrapyrrole compound.
has_obo_namespace: chebi_ontology
has_related_synonym: acyclic tetrapyrrole anion
has_related_synonym: acyclic tetrapyrrole anions
has_related_synonym: linear tetrapyrrole anions
id: CHEBI:59252
in_subset: 3 STAR

Axiom
annotated source: linear tetrapyrrole anion
annotated property: has_related_synonym
annotated target: acyclic tetrapyrrole anion
database_cross_reference: ChEBI

Axiom
annotated source: linear tetrapyrrole anion
annotated property: has_related_synonym
annotated target: acyclic tetrapyrrole anions
database_cross_reference: ChEBI

Axiom
annotated source: linear tetrapyrrole anion
annotated property: has_related_synonym
annotated target: linear tetrapyrrole anions
database_cross_reference: ChEBI

phosphoric acids
type: Class
subclass of: phosphorus oxoacid
definition: Compounds containing one or more phosphoric acid units.
has_obo_namespace: chebi_ontology
id: CHEBI:59698
in_subset: 3 STAR

electrophilic reagent
type: Class
subclass of: reagent
subclass of: Lewis acid

nucleophilic reagent
type: Class
subclass of: reagent
subclass of: Lewis base
definition: A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.
has_obo_namespace: chebi_ontology
has_related_synonym: nucleophile
has_related_synonym: nucleophiles
has_related_synonym: nucleophilic reagents
id: CHEBI:59740
in_subset: 3 STAR

Axiom
annotated source: nucleophilic reagent
annotated property: has_related_synonym
annotated target: nucleophile
database_cross_reference: ChEBI

Axiom
annotated source: nucleophilic reagent
annotated property: has_related_synonym
annotated target: nucleophiles
database_cross_reference: ChEBI

Axiom
annotated source: nucleophilic reagent
annotated property: has_related_synonym
annotated target: nucleophilic reagents
database_cross_reference: ChEBI

chemical substance
type: Class
subclass of: chemical entity
definition: A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types.
has_obo_namespace: chebi_ontology
has_related_synonym: Chemische Substanz
id: CHEBI:59999
in_subset: 3 STAR

Axiom
annotated source: chemical substance
annotated property: has_related_synonym
annotated target: Chemische Substanz
database_cross_reference: ChEBI

mixture
type: Class
subclass of: chemical substance
definition: A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind.
has_obo_namespace: chebi_ontology
has_related_synonym: Mischung
id: CHEBI:60004
in_subset: 3 STAR

Axiom
annotated source: mixture
annotated property: has_related_synonym
annotated target: Mischung
database_cross_reference: ChEBI

polymer
type: Class
subclass of: mixture
subclass of: Restriction
  on property: has part
  some values from: macromolecule
definition: A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc..
database_cross_reference: Wikipedia:Polymer
has_exact_synonym: Polymer
has_obo_namespace: chebi_ontology
has_related_synonym: Kunststoff
id: CHEBI:60027
in_subset: 3 STAR

Axiom
annotated source: polymer
annotated property: has_exact_synonym
annotated target: Polymer
database_cross_reference: ChEBI

Axiom
annotated source: polymer
annotated property: has_related_synonym
annotated target: Kunststoff
database_cross_reference: ChEBI

homopolymer
type: Class
subclass of: polymer

poly(alkylene) polymer
type: Class
subclass of: homopolymer

polyethylene polymer
type: Class
subclass of: poly(alkylene) polymer
in_subset: envoPlastics

polyester polymer
type: Class
subclass of: polymer
in_subset: envoPlastics

ionic polymer
type: Class
subclass of: polymer
subclass of: Restriction
  on property: has part
  some values from: ionic macromolecule
definition: An ionic polymer is a polymer, composed of ionic macromolecules.
has_obo_namespace: chebi_ontology
has_related_synonym: polyionic polymer
id: CHEBI:60164
in_subset: 3 STAR

Axiom
annotated source: ionic polymer
annotated property: has_related_synonym
annotated target: polyionic polymer
database_cross_reference: ChEBI

monovalent inorganic cation
type: Class
subclass of: inorganic cation
definition: An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one.
has_obo_namespace: chebi_ontology
has_related_synonym: a monovalent cation
id: CHEBI:60242
in_subset: 3 STAR

Axiom
annotated source: monovalent inorganic cation
annotated property: has_related_synonym
annotated target: a monovalent cation
database_cross_reference: UniProt

aluminium ion
type: Class
subclass of: elemental aluminium
subclass of: inorganic ion

peptide zwitterion
type: Class
subclass of: zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: peptide
definition: Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged.
charge: 0
formula: C2H4NO2R(C2H2NOR)n
has_obo_namespace: chebi_ontology
has_related_synonym: a peptide
has_related_synonym: peptide zwitterions
id: CHEBI:60466
in_subset: 3 STAR

Axiom
annotated source: peptide zwitterion
annotated property: has_related_synonym
annotated target: a peptide
database_cross_reference: UniProt

Axiom
annotated source: peptide zwitterion
annotated property: has_related_synonym
annotated target: peptide zwitterions
database_cross_reference: ChEBI

NMDA receptor antagonist
type: Class
subclass of: excitatory amino acid antagonist

polyurethane polymer
type: Class
subclass of: homopolymer
in_subset: envoPlastics

excitatory amino acid antagonist
type: Class
subclass of: antagonist

amino monosaccharide
type: Class
subclass of: amino sugar

nucleobase-containing molecular entity
type: Class
subclass of: heteroarene
subclass of: nitrogen molecular entity
subclass of: Restriction
  on property: has functional parent
  some values from: nucleobase
definition: Any compound that has a nucleobase as a part.
has_obo_namespace: chebi_ontology
has_related_synonym: nucleobase-containing compound
has_related_synonym: nucleobase-containing compounds
has_related_synonym: nucleobase-containing molecular entities
id: CHEBI:61120
in_subset: 3 STAR

Axiom
annotated source: nucleobase-containing molecular entity
annotated property: has_related_synonym
annotated target: nucleobase-containing compound
database_cross_reference: SUBMITTER

Axiom
annotated source: nucleobase-containing molecular entity
annotated property: has_related_synonym
annotated target: nucleobase-containing compounds
database_cross_reference: ChEBI

Axiom
annotated source: nucleobase-containing molecular entity
annotated property: has_related_synonym
annotated target: nucleobase-containing molecular entities
database_cross_reference: ChEBI

brevetoxin A
type: Class
subclass of: ciguatoxin

ciguatoxin
type: Class
subclass of: polycyclic ether

guanyl nucleotide
type: Class
subclass of: purine nucleotide

adenyl nucleotide
type: Class
subclass of: purine nucleotide

guanyl ribonucleotide
type: Class
subclass of: purine ribonucleotide
subclass of: guanyl nucleotide

adenyl ribonucleotide
type: Class
subclass of: purine ribonucleotide
subclass of: adenyl nucleotide

poly(ethylene terephthalate) polymer
type: Class
subclass of: polyester polymer
in_subset: envoPlastics

polyanionic polymer
type: Class
subclass of: ionic polymer
subclass of: Restriction
  on property: has part
  some values from: polyanionic macromolecule
definition: A polymer, composed of polyanion macromolecules.
has_obo_namespace: chebi_ontology
has_related_synonym: polyanion
has_related_synonym: polyanions
id: CHEBI:61469
in_subset: 3 STAR

Axiom
annotated source: polyanionic polymer
annotated property: has_related_synonym
annotated target: polyanion
database_cross_reference: ChEBI

Axiom
annotated source: polyanionic polymer
annotated property: has_related_synonym
annotated target: polyanions
database_cross_reference: ChEBI

vinyl polymer
type: Class
subclass of: polyethylene polymer

polystyrene polymer
type: Class
subclass of: vinyl polymer
in_subset: envoPlastics

signalling molecule
type: Class
subclass of: molecular messenger

reactive nitrogen species
type: Class
subclass of: nitrogen molecular entity

amorphous cellulose
type: Class
subclass of: (1->4)-beta-D-glucan
subclass of: exopolysaccharide

crystalline cellulose
type: Class
subclass of: (1->4)-beta-D-glucan
subclass of: exopolysaccharide

emulsifier
type: Class
subclass of: chemical role

aluminium cation
type: Class
subclass of: metal cation
subclass of: aluminium ion

oxidising agent
type: Class
subclass of: chemical role
definition: A substance that removes electrons from another reactant in a redox reaction.
has_obo_namespace: chebi_ontology
has_related_synonym: oxidant
has_related_synonym: oxidants
has_related_synonym: oxidiser
has_related_synonym: oxidisers
has_related_synonym: oxidising agents
has_related_synonym: oxidizer
has_related_synonym: oxidizers
has_related_synonym: oxidizing agent
has_related_synonym: oxidizing agents
id: CHEBI:63248
in_subset: 3 STAR

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidant
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidants
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidiser
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidisers
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidising agents
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidizer
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidizers
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidizing agent
database_cross_reference: ChEBI

Axiom
annotated source: oxidising agent
annotated property: has_related_synonym
annotated target: oxidizing agents
database_cross_reference: ChEBI

carbohydrate derivative
type: Class
subclass of: carbohydrates and carbohydrate derivatives
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate
definition: Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds.
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate derivatives
has_related_synonym: derivatised carbohydrate
has_related_synonym: derivatised carbohydrates
has_related_synonym: derivatized carbohydrate
has_related_synonym: derivatized carbohydrates
id: CHEBI:63299
in_subset: 3 STAR

Axiom
annotated source: carbohydrate derivative
annotated property: has_related_synonym
annotated target: carbohydrate derivatives
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: has_related_synonym
annotated target: derivatised carbohydrate
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: has_related_synonym
annotated target: derivatised carbohydrates
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: has_related_synonym
annotated target: derivatized carbohydrate
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate derivative
annotated property: has_related_synonym
annotated target: derivatized carbohydrates
database_cross_reference: ChEBI

monosaccharide derivative
type: Class
subclass of: carbohydrate derivative

pentose derivative
type: Class
subclass of: monosaccharide derivative

carbohydrate acid derivative
type: Class
subclass of: carbohydrate derivative
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbohydrate acid derivative anion
definition: A carbohydrate derivative that is formally obtained from a carbohydrate acid.
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate acid derivatives
id: CHEBI:63436
in_subset: 3 STAR

Axiom
annotated source: carbohydrate acid derivative
annotated property: has_related_synonym
annotated target: carbohydrate acid derivatives
database_cross_reference: ChEBI

branched-chain amino-acid anion
type: Class
subclass of: amino-acid anion

monoamine
type: Class
subclass of: aralkylamino compound
definition: An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.
database_cross_reference: PMID:21822758
database_cross_reference: PMID:21993877
database_cross_reference: PMID:22005599
database_cross_reference: PMID:22082101
database_cross_reference: PMID:22153577
database_cross_reference: PMID:22213370
database_cross_reference: PMID:22218931
database_cross_reference: PMID:22342987
database_cross_reference: PMID:22371656
has_obo_namespace: chebi_ontology
has_related_synonym: monoamines
has_related_synonym: naturally occurring monoamine
has_related_synonym: naturally occurring monoamines
id: CHEBI:63534
in_subset: 3 STAR

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:21822758
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:21993877
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22005599
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22082101
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22153577
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22213370
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22218931
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22342987
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: database_cross_reference
annotated target: PMID:22371656
source: Europe PMC

Axiom
annotated source: monoamine
annotated property: has_related_synonym
annotated target: monoamines
database_cross_reference: ChEBI

Axiom
annotated source: monoamine
annotated property: has_related_synonym
annotated target: naturally occurring monoamine
database_cross_reference: ChEBI

Axiom
annotated source: monoamine
annotated property: has_related_synonym
annotated target: naturally occurring monoamines
database_cross_reference: ChEBI

carbohydrate acid derivative anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbohydrate acid derivative
definition: A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative.
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate acid anion derivative
has_related_synonym: carbohydrate acid anion derivatives
has_related_synonym: carbohydrate acid derivative anions
id: CHEBI:63551
in_subset: 3 STAR

Axiom
annotated source: carbohydrate acid derivative anion
annotated property: has_related_synonym
annotated target: carbohydrate acid anion derivative
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid derivative anion
annotated property: has_related_synonym
annotated target: carbohydrate acid anion derivatives
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrate acid derivative anion
annotated property: has_related_synonym
annotated target: carbohydrate acid derivative anions
database_cross_reference: ChEBI

1,1-diol
type: Class
subclass of: alcohol

ketone hydrate
type: Class
subclass of: 1,1-diol

food additive
type: Class
subclass of: application
subclass of: food component
definition: Any substance which is added to food to preserve or enhance its flavour and/or appearance.
database_cross_reference: Wikipedia:Food_additive
has_obo_namespace: chebi_ontology
has_related_synonym: food additives
id: CHEBI:64047
in_subset: 3 STAR

Axiom
annotated source: food additive
annotated property: has_related_synonym
annotated target: food additives
database_cross_reference: ChEBI

food acidity regulator
type: Class
subclass of: food additive
definition: A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.
database_cross_reference: Wikipedia:Acidity_regulator
has_obo_namespace: chebi_ontology
has_related_synonym: acidity regulator
has_related_synonym: acidity regulators
has_related_synonym: food acidity regulators
has_related_synonym: pH control agent
has_related_synonym: pH control agents
id: CHEBI:64049
in_subset: 3 STAR

Axiom
annotated source: food acidity regulator
annotated property: has_related_synonym
annotated target: acidity regulator
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: has_related_synonym
annotated target: acidity regulators
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: has_related_synonym
annotated target: food acidity regulators
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: has_related_synonym
annotated target: pH control agent
database_cross_reference: ChEBI

Axiom
annotated source: food acidity regulator
annotated property: has_related_synonym
annotated target: pH control agents
database_cross_reference: ChEBI

aralkylamino compound
type: Class
subclass of: organic amino compound
definition: An organic amino compound in which an aminoalkyl group is linked to an arene.
has_obo_namespace: chebi_ontology
has_related_synonym: aralkylamino compounds
id: CHEBI:64365
in_subset: 3 STAR

Axiom
annotated source: aralkylamino compound
annotated property: has_related_synonym
annotated target: aralkylamino compounds
database_cross_reference: ChEBI

somatostatin
type: Class
subclass of: heterodetic cyclic peptide
subclass of: peptide hormone
definition: A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14.
charge: 0
formula: C76H104N18O19S2
inchikey: NHXLMOGPVYXJNR-ATOGVRKGSA-N
mass: 1637.87800
monoisotopicmass: 1636.71666
database_cross_reference: CAS:38916-34-6
database_cross_reference: Drug_Central:2997
database_cross_reference: HMDB:HMDB0013072
database_cross_reference: KEGG:C16022
database_cross_reference: KEGG:D07431
database_cross_reference: LINCS:LSM-5326
database_cross_reference: PMID:21922516
database_cross_reference: PMID:22129035
database_cross_reference: PMID:22147011
database_cross_reference: PMID:22251942
database_cross_reference: PMID:22483686
database_cross_reference: PMID:22509294
database_cross_reference: Reaxys:10148626
database_cross_reference: Wikipedia:Somatostatin
has_exact_synonym: L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
has_obo_namespace: chebi_ontology
has_related_synonym: Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]
has_related_synonym: L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide
has_related_synonym: Somatostatin-1
has_related_synonym: Somatostatin-14
has_related_synonym: Synthetic growth hormone release-inhibiting hormone
has_related_synonym: somatostatin
has_related_synonym: somatostatina
has_related_synonym: somatostatine
has_related_synonym: somatostatinum
id: CHEBI:64628
in_subset: 3 STAR

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: CAS:38916-34-6
source: ChemIDplus

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: CAS:38916-34-6
source: KEGG DRUG

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: Drug_Central:2997
source: DrugCentral

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:21922516
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22129035
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22147011
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22251942
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22483686
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: PMID:22509294
source: Europe PMC

Axiom
annotated source: somatostatin
annotated property: database_cross_reference
annotated target: Reaxys:10148626
source: Reaxys

Axiom
annotated source: somatostatin
annotated property: has_exact_synonym
annotated target: L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]
database_cross_reference: ChEBI

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide
database_cross_reference: ChemIDplus

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: Somatostatin-1
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: Somatostatin-14
database_cross_reference: KEGG_COMPOUND

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: Synthetic growth hormone release-inhibiting hormone
database_cross_reference: ChemIDplus

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: somatostatin
database_cross_reference: KEGG_DRUG
has_synonym_type: INN

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: somatostatina
database_cross_reference: ChemIDplus
has_synonym_type: INN

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: somatostatine
database_cross_reference: ChemIDplus
has_synonym_type: INN

Axiom
annotated source: somatostatin
annotated property: has_related_synonym
annotated target: somatostatinum
database_cross_reference: ChemIDplus
has_synonym_type: INN

one-carbon compound
type: Class
subclass of: organic molecular entity
definition: An organic molecular entity containing a single carbon atom (C1).
has_obo_namespace: chebi_ontology
has_related_synonym: one-carbon compounds
id: CHEBI:64708
in_subset: 3 STAR

Axiom
annotated source: one-carbon compound
annotated property: has_related_synonym
annotated target: one-carbon compounds
database_cross_reference: ChEBI

organic acid
type: Class
subclass of: organic molecular entity
definition: Any organic molecular entity that is acidic and contains carbon in covalent linkage.
has_obo_namespace: chebi_ontology
has_related_synonym: organic acids
id: CHEBI:64709
in_subset: 3 STAR

Axiom
annotated source: organic acid
annotated property: has_related_synonym
annotated target: organic acids
database_cross_reference: ChEBI

trivalent inorganic cation
type: Class
subclass of: inorganic cation

poison
type: Class
subclass of: biological role
definition: Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
database_cross_reference: Wikipedia:Poison
has_obo_namespace: chebi_ontology
has_related_synonym: poisonous agent
has_related_synonym: poisonous agents
has_related_synonym: poisonous substance
has_related_synonym: poisonous substances
has_related_synonym: poisons
has_related_synonym: toxic agent
has_related_synonym: toxic agents
has_related_synonym: toxic substance
has_related_synonym: toxic substances
id: CHEBI:64909
in_subset: 3 STAR

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: poisonous agent
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: poisonous agents
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: poisonous substance
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: poisonous substances
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: poisons
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: toxic agent
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: toxic agents
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: toxic substance
database_cross_reference: ChEBI

Axiom
annotated source: poison
annotated property: has_related_synonym
annotated target: toxic substances
database_cross_reference: ChEBI

polysaccharide derivative
type: Class
subclass of: glycan
subclass of: biomacromolecule
subclass of: carbohydrate derivative
subclass of: Restriction
  on property: has functional parent
  some values from: polysaccharide
definition: A carbohydrate derivative that is any derivative of a polysaccharide.
has_obo_namespace: chebi_ontology
has_related_synonym: polysaccharide derivatives
id: CHEBI:65212
in_subset: 3 STAR

Axiom
annotated source: polysaccharide derivative
annotated property: has_related_synonym
annotated target: polysaccharide derivatives
database_cross_reference: ChEBI

food preservative
type: Class
subclass of: food additive
definition: Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.
has_obo_namespace: chebi_ontology
has_related_synonym: food preservatives
id: CHEBI:65255
in_subset: 3 STAR

Axiom
annotated source: food preservative
annotated property: has_related_synonym
annotated target: food preservatives
database_cross_reference: ChEBI

antimicrobial food preservative
type: Class
subclass of: antimicrobial agent
subclass of: food preservative
definition: A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).
has_obo_namespace: chebi_ontology
has_related_synonym: antimicrobial food preservatives
has_related_synonym: antimicrobial preservative
has_related_synonym: antimicrobial preservatives
id: CHEBI:65256
in_subset: 3 STAR

Axiom
annotated source: antimicrobial food preservative
annotated property: has_related_synonym
annotated target: antimicrobial food preservatives
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial food preservative
annotated property: has_related_synonym
annotated target: antimicrobial preservative
database_cross_reference: ChEBI

Axiom
annotated source: antimicrobial food preservative
annotated property: has_related_synonym
annotated target: antimicrobial preservatives
database_cross_reference: ChEBI

primary ammonium ion
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: primary amino compound
definition: An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3.
charge: +1
formula: H3NR
mass: 17.031
monoisotopicmass: 17.02655
smiles: [NH3+][*]
has_obo_namespace: chebi_ontology
has_related_synonym: a primary amine
has_related_synonym: substituted ammonium
id: CHEBI:65296
in_subset: 3 STAR

Axiom
annotated source: primary ammonium ion
annotated property: has_related_synonym
annotated target: a primary amine
database_cross_reference: UniProt

Axiom
annotated source: primary ammonium ion
annotated property: has_related_synonym
annotated target: substituted ammonium
database_cross_reference: ChEBI

N-alkylglycine
type: Class
subclass of: glycine derivative
subclass of: non-proteinogenic alpha-amino acid

anti-inflammatory agent
type: Class
subclass of: application
definition: Any compound that has anti-inflammatory effects.
has_obo_namespace: chebi_ontology
has_related_synonym: anti-inflammatory agents
has_related_synonym: antiinflammatory agent
has_related_synonym: antiinflammatory agents
id: CHEBI:67079
in_subset: 3 STAR

Axiom
annotated source: anti-inflammatory agent
annotated property: has_related_synonym
annotated target: anti-inflammatory agents
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory agent
annotated property: has_related_synonym
annotated target: antiinflammatory agent
database_cross_reference: ChEBI

Axiom
annotated source: anti-inflammatory agent
annotated property: has_related_synonym
annotated target: antiinflammatory agents
database_cross_reference: ChEBI

(R)-noradrenaline(1+)
type: Class
subclass of: independent continuant
subclass of: noradrenaline(1+)
subclass of: Restriction
  on property: has role
  some values from: human metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: (R)-noradrenaline
definition: An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3.
charge: +1
formula: C8H12NO3
inchi: InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1
inchikey: SFLSHLFXELFNJZ-QMMMGPOBSA-O
mass: 170.187
monoisotopicmass: 170.08117
smiles: C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O
database_cross_reference: PDBeChem:E5E
has_exact_synonym: (2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium
has_obo_namespace: chebi_ontology
has_related_synonym: (R)-noradrenaline
has_related_synonym: (R)-noradrenaline cation
has_related_synonym: (R)-noradrenalinium cation
has_related_synonym: (R)-noradrenalinium(1+)
id: CHEBI:72587
in_subset: 3 STAR

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: has_exact_synonym
annotated target: (2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium
database_cross_reference: IUPAC
has_synonym_type: IUPAC NAME

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: has_related_synonym
annotated target: (R)-noradrenaline
database_cross_reference: UniProt

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: has_related_synonym
annotated target: (R)-noradrenaline cation
database_cross_reference: ChEBI

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: has_related_synonym
annotated target: (R)-noradrenalinium cation
database_cross_reference: ChEBI

Axiom
annotated source: (R)-noradrenaline(1+)
annotated property: has_related_synonym
annotated target: (R)-noradrenalinium(1+)
database_cross_reference: ChEBI

organic molecule
type: Class
subclass of: molecule
subclass of: organic molecular entity
definition: Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.
has_obo_namespace: chebi_ontology
has_related_synonym: organic compound
has_related_synonym: organic compounds
has_related_synonym: organic molecules
id: CHEBI:72695
in_subset: 3 STAR

Axiom
annotated source: organic molecule
annotated property: has_related_synonym
annotated target: organic compound
database_cross_reference: ChEBI

Axiom
annotated source: organic molecule
annotated property: has_related_synonym
annotated target: organic compounds
database_cross_reference: ChEBI

Axiom
annotated source: organic molecule
annotated property: has_related_synonym
annotated target: organic molecules
database_cross_reference: ChEBI

exopolysaccharide
type: Class
subclass of: biomacromolecule
definition: A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment.
database_cross_reference: MetaCyc:Exopolysaccharides
database_cross_reference: PMID:11160795
database_cross_reference: PMID:11785425
database_cross_reference: PMID:1444258
database_cross_reference: PMID:15738217
database_cross_reference: PMID:16075348
database_cross_reference: PMID:17440912
database_cross_reference: PMID:18097339
database_cross_reference: PMID:19453747
database_cross_reference: PMID:20172021
database_cross_reference: PMID:20631870
database_cross_reference: PMID:20718297
database_cross_reference: PMID:2688547
database_cross_reference: PMID:6354590
database_cross_reference: Wikipedia:Exopolysaccharide
database_cross_reference: Wikipedia:Extracellular_polymeric_substance
has_obo_namespace: chebi_ontology
has_related_synonym: exopolysaccharides
has_related_synonym: extracellular polymeric substance
has_related_synonym: extracellular polymeric substances
id: CHEBI:72813
in_subset: 3 STAR

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:11160795
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:11785425
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:1444258
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:15738217
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:16075348
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:17440912
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:18097339
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:19453747
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:20172021
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:20631870
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:20718297
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:2688547
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: database_cross_reference
annotated target: PMID:6354590
source: Europe PMC

Axiom
annotated source: exopolysaccharide
annotated property: has_related_synonym
annotated target: exopolysaccharides
database_cross_reference: ChEBI

Axiom
annotated source: exopolysaccharide
annotated property: has_related_synonym
annotated target: extracellular polymeric substance
database_cross_reference: ChEBI

Axiom
annotated source: exopolysaccharide
annotated property: has_related_synonym
annotated target: extracellular polymeric substances
database_cross_reference: ChEBI

divinyl chlorophyll a
type: Class
subclass of: methyl ester
subclass of: chlorophyll

divinyl chlorophyll b
type: Class
subclass of: methyl ester
subclass of: chlorophyll

indole skeleton
type: Class
subclass of: organic heterobicyclic ring
definition: A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring.
charge: 0
formula: C8N
mass: 110.09230
monoisotopicmass: 110.00307
smiles: C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*
has_obo_namespace: chebi_ontology
id: CHEBI:73398
in_subset: 3 STAR

organic heterobicyclic ring
type: Class
subclass of: cyclic organic group
definition: A bicyclic organic group that contains both carbon and hetero atoms.
has_obo_namespace: chebi_ontology
has_related_synonym: organic heterobicyclic rings
id: CHEBI:73541
in_subset: 3 STAR

Axiom
annotated source: organic heterobicyclic ring
annotated property: has_related_synonym
annotated target: organic heterobicyclic rings
database_cross_reference: ChEBI

eukaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
has_obo_namespace: chebi_ontology
has_related_synonym: eukaryotic metabolites
id: CHEBI:75763
in_subset: 3 STAR

Axiom
annotated source: eukaryotic metabolite
annotated property: has_related_synonym
annotated target: eukaryotic metabolites
database_cross_reference: ChEBI

animal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
has_alternative_id: CHEBI:77721
has_alternative_id: CHEBI:77743
has_obo_namespace: chebi_ontology
has_related_synonym: animal metabolites
id: CHEBI:75767
in_subset: 3 STAR

Axiom
annotated source: animal metabolite
annotated property: has_related_synonym
annotated target: animal metabolites
database_cross_reference: ChEBI

mammalian metabolite
type: Class
subclass of: animal metabolite
definition: Any animal metabolite produced during a metabolic reaction in mammals.
has_alternative_id: CHEBI:77464
has_alternative_id: CHEBI:77744
has_obo_namespace: chebi_ontology
has_related_synonym: mammalian metabolites
id: CHEBI:75768
in_subset: 3 STAR

Axiom
annotated source: mammalian metabolite
annotated property: has_related_synonym
annotated target: mammalian metabolites
database_cross_reference: ChEBI

mouse metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
has_obo_namespace: chebi_ontology
has_related_synonym: Mus musculus metabolite
has_related_synonym: Mus musculus metabolites
has_related_synonym: mouse metabolites
id: CHEBI:75771
in_subset: 3 STAR

Axiom
annotated source: mouse metabolite
annotated property: has_related_synonym
annotated target: Mus musculus metabolite
database_cross_reference: ChEBI

Axiom
annotated source: mouse metabolite
annotated property: has_related_synonym
annotated target: Mus musculus metabolites
database_cross_reference: ChEBI

Axiom
annotated source: mouse metabolite
annotated property: has_related_synonym
annotated target: mouse metabolites
database_cross_reference: ChEBI

Saccharomyces cerevisiae metabolite
type: Class
subclass of: fungal metabolite
definition: Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
has_alternative_id: CHEBI:76949
has_alternative_id: CHEBI:76951
has_obo_namespace: chebi_ontology
has_related_synonym: S. cerevisiae metabolite
has_related_synonym: S. cerevisiae metabolites
has_related_synonym: S. cerevisiae secondary metabolite
has_related_synonym: S. cerevisiae secondary metabolites
has_related_synonym: Saccharomyces cerevisiae metabolites
has_related_synonym: Saccharomyces cerevisiae secondary metabolites
has_related_synonym: baker's yeast metabolite
has_related_synonym: baker's yeast metabolites
has_related_synonym: baker's yeast secondary metabolite
has_related_synonym: baker's yeast secondary metabolites
id: CHEBI:75772
in_subset: 3 STAR

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: S. cerevisiae metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: S. cerevisiae metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: S. cerevisiae secondary metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: S. cerevisiae secondary metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: Saccharomyces cerevisiae metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: Saccharomyces cerevisiae secondary metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: baker's yeast metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: baker's yeast metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: baker's yeast secondary metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Saccharomyces cerevisiae metabolite
annotated property: has_related_synonym
annotated target: baker's yeast secondary metabolites
database_cross_reference: ChEBI

prokaryotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
has_obo_namespace: chebi_ontology
has_related_synonym: prokaryotic metabolites
id: CHEBI:75787
in_subset: 3 STAR

Axiom
annotated source: prokaryotic metabolite
annotated property: has_related_synonym
annotated target: prokaryotic metabolites
database_cross_reference: ChEBI

iron sulfides
type: Class
subclass of: iron molecular entity
subclass of: sulfide salt

iron(2+) sulfides
type: Class
subclass of: iron sulfides

xenobiotic metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced by metabolism of a xenobiotic compound.
has_obo_namespace: chebi_ontology
has_related_synonym: xenobiotic metabolites
id: CHEBI:76206
in_subset: 3 STAR

Axiom
annotated source: xenobiotic metabolite
annotated property: has_related_synonym
annotated target: xenobiotic metabolites
database_cross_reference: ChEBI

greenhouse gas
type: Class
subclass of: chemical role
in_subset: envoPolar

propellant
type: Class
subclass of: application

EC 1.* (oxidoreductase) inhibitor
type: Class
subclass of: enzyme inhibitor

EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
type: Class
subclass of: EC 1.* (oxidoreductase) inhibitor

EC 3.* (hydrolase) inhibitor
type: Class
subclass of: enzyme inhibitor
definition: Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
database_cross_reference: Wikipedia:Hydrolase
has_obo_namespace: chebi_ontology
has_related_synonym: EC 3.* (hydrolase) inhibitors
has_related_synonym: EC 3.* inhibitor
has_related_synonym: EC 3.* inhibitors
has_related_synonym: EC 3.*.*.* inhibitor
has_related_synonym: EC 3.*.*.* inhibitors
has_related_synonym: hydrolase (EC 3.*) inhibitor
has_related_synonym: hydrolase (EC 3.*) inhibitors
has_related_synonym: hydrolase inhibitor
has_related_synonym: hydrolase inhibitors
id: CHEBI:76759
in_subset: 3 STAR

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.* (hydrolase) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.* inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.*.*.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.*.*.* inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: hydrolase (EC 3.*) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: hydrolase (EC 3.*) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: hydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.* (hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: hydrolase inhibitors
database_cross_reference: ChEBI

EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
type: Class
subclass of: EC 3.* (hydrolase) inhibitor
definition: Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
has_obo_namespace: chebi_ontology
has_related_synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
has_related_synonym: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
has_related_synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
has_related_synonym: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
has_related_synonym: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
has_related_synonym: EC 3.5.* inhibitor
has_related_synonym: EC 3.5.* inhibitors
id: CHEBI:76764
in_subset: 3 STAR

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.* inhibitors
database_cross_reference: ChEBI

EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
type: Class
subclass of: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
definition: An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
has_obo_namespace: chebi_ontology
has_related_synonym: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
has_related_synonym: EC 3.5.1.* inhibitor
has_related_synonym: EC 3.5.1.* inhibitors
has_related_synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
has_related_synonym: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
id: CHEBI:76807
in_subset: 3 STAR

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.1.* inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.1.* inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
annotated property: has_related_synonym
annotated target: non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
database_cross_reference: ChEBI

EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
type: Class
subclass of: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

EC 1.14.14.1 (unspecific monooxygenase) inhibitor
type: Class
subclass of: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor

plant metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
has_alternative_id: CHEBI:75766
has_alternative_id: CHEBI:76925
has_obo_namespace: chebi_ontology
has_related_synonym: plant metabolites
has_related_synonym: plant secondary metabolites
id: CHEBI:76924
in_subset: 3 STAR

Axiom
annotated source: plant metabolite
annotated property: has_related_synonym
annotated target: plant metabolites
database_cross_reference: ChEBI

Axiom
annotated source: plant metabolite
annotated property: has_related_synonym
annotated target: plant secondary metabolites
database_cross_reference: ChEBI

pathway inhibitor
type: Class
subclass of: enzyme inhibitor

fungal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
has_alternative_id: CHEBI:75765
has_alternative_id: CHEBI:76947
has_obo_namespace: chebi_ontology
has_related_synonym: fungal metabolites
id: CHEBI:76946
in_subset: 3 STAR

Axiom
annotated source: fungal metabolite
annotated property: has_related_synonym
annotated target: fungal metabolites
database_cross_reference: ChEBI

human xenobiotic metabolite
type: Class
subclass of: xenobiotic metabolite
subclass of: human metabolite
definition: Any human metabolite produced by metabolism of a xenobiotic compound in humans.
has_obo_namespace: chebi_ontology
has_related_synonym: human xenobiotic metabolites
id: CHEBI:76967
in_subset: 3 STAR

Axiom
annotated source: human xenobiotic metabolite
annotated property: has_related_synonym
annotated target: human xenobiotic metabolites
database_cross_reference: ChEBI

bacterial metabolite
type: Class
subclass of: prokaryotic metabolite
definition: Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
has_alternative_id: CHEBI:75760
has_alternative_id: CHEBI:76970
has_obo_namespace: chebi_ontology
id: CHEBI:76969
in_subset: 3 STAR

Escherichia coli metabolite
type: Class
subclass of: bacterial metabolite
definition: Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
has_obo_namespace: chebi_ontology
has_related_synonym: E.coli metabolite
has_related_synonym: E.coli metabolites
has_related_synonym: Escherichia coli metabolites
id: CHEBI:76971
in_subset: 3 STAR

Axiom
annotated source: Escherichia coli metabolite
annotated property: has_related_synonym
annotated target: E.coli metabolite
database_cross_reference: ChEBI

Axiom
annotated source: Escherichia coli metabolite
annotated property: has_related_synonym
annotated target: E.coli metabolites
database_cross_reference: ChEBI

Axiom
annotated source: Escherichia coli metabolite
annotated property: has_related_synonym
annotated target: Escherichia coli metabolites
database_cross_reference: ChEBI

human metabolite
type: Class
subclass of: mammalian metabolite
definition: Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
has_alternative_id: CHEBI:75770
has_alternative_id: CHEBI:77123
has_obo_namespace: chebi_ontology
has_related_synonym: H. sapiens metabolite
has_related_synonym: H. sapiens metabolites
has_related_synonym: Homo sapiens metabolite
has_related_synonym: Homo sapiens metabolites
id: CHEBI:77746
in_subset: 3 STAR

Axiom
annotated source: human metabolite
annotated property: has_related_synonym
annotated target: H. sapiens metabolite
database_cross_reference: ChEBI

Axiom
annotated source: human metabolite
annotated property: has_related_synonym
annotated target: H. sapiens metabolites
database_cross_reference: ChEBI

Axiom
annotated source: human metabolite
annotated property: has_related_synonym
annotated target: Homo sapiens metabolite
database_cross_reference: ChEBI

Axiom
annotated source: human metabolite
annotated property: has_related_synonym
annotated target: Homo sapiens metabolites
database_cross_reference: ChEBI

EC 3.5.1.4 (amidase) inhibitor
type: Class
subclass of: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
definition: An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
database_cross_reference: Wikipedia:Amidase
has_obo_namespace: chebi_ontology
has_related_synonym: EC 3.5.1.4 (amidase) inhibitors
has_related_synonym: EC 3.5.1.4 inhibitor
has_related_synonym: EC 3.5.1.4 inhibitors
has_related_synonym: N-acetylaminohydrolase inhibitor
has_related_synonym: N-acetylaminohydrolase inhibitors
has_related_synonym: acylamidase inhibitor
has_related_synonym: acylamidase inhibitors
has_related_synonym: acylamide amidohydrolase inhibitor
has_related_synonym: acylamide amidohydrolase inhibitors
has_related_synonym: amidase (EC 3.5.1.4) inhibitor
has_related_synonym: amidase (EC 3.5.1.4) inhibitors
has_related_synonym: amidase inhibitor
has_related_synonym: amidase inhibitors
has_related_synonym: amidohydrolase inhibitor
has_related_synonym: amidohydrolase inhibitors
has_related_synonym: deaminase inhibitor
has_related_synonym: deaminase inhibitors
has_related_synonym: fatty acylamidase inhibitor
has_related_synonym: fatty acylamidase inhibitors
id: CHEBI:77941
in_subset: 3 STAR

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.1.4 (amidase) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.1.4 inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: EC 3.5.1.4 inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: N-acetylaminohydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: N-acetylaminohydrolase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: acylamidase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: acylamidase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: acylamide amidohydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: acylamide amidohydrolase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: amidase (EC 3.5.1.4) inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: amidase (EC 3.5.1.4) inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: amidase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: amidase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: amidohydrolase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: amidohydrolase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: deaminase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: deaminase inhibitors
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: fatty acylamidase inhibitor
database_cross_reference: ChEBI

Axiom
annotated source: EC 3.5.1.4 (amidase) inhibitor
annotated property: has_related_synonym
annotated target: fatty acylamidase inhibitors
database_cross_reference: ChEBI

raising agent
type: Class
subclass of: food additive

food packaging gas
type: Class
subclass of: food additive
definition: A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container.
database_cross_reference: Wikipedia:Packaging_gas
has_obo_namespace: chebi_ontology
has_related_synonym: food packaging gases
id: CHEBI:77974
in_subset: 3 STAR

Axiom
annotated source: food packaging gas
annotated property: has_related_synonym
annotated target: food packaging gases
database_cross_reference: ChEBI

food propellant
type: Class
subclass of: food additive
subclass of: propellant

fatty acid anion 28:0
type: Class
subclass of: saturated fatty acid anion

food component
type: Class
subclass of: physiological role
definition: A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
has_obo_namespace: chebi_ontology
has_related_synonym: dietary component
has_related_synonym: dietary components
has_related_synonym: food components
id: CHEBI:78295
in_subset: 3 STAR

Axiom
annotated source: food component
annotated property: has_related_synonym
annotated target: dietary component
database_cross_reference: ChEBI

Axiom
annotated source: food component
annotated property: has_related_synonym
annotated target: dietary components
database_cross_reference: ChEBI

Axiom
annotated source: food component
annotated property: has_related_synonym
annotated target: food components
database_cross_reference: ChEBI

environmental contaminant
type: Class
subclass of: chemical role

refrigerant
type: Class
subclass of: application
definition: A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
database_cross_reference: Wikipedia:Refrigerant
has_obo_namespace: chebi_ontology
has_related_synonym: refrigerants
id: CHEBI:78433
in_subset: 3 STAR

Axiom
annotated source: refrigerant
annotated property: has_related_synonym
annotated target: refrigerants
database_cross_reference: ChEBI

alpha-amino acid zwitterion
type: Class
subclass of: amino acid zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: alpha-amino acid
definition: An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3.
charge: 0
formula: C2H4NO2R
mass: 74.059
monoisotopicmass: 74.02420
smiles: [NH3+]C([*])C([O-])=O
has_alternative_id: CHEBI:83409
database_cross_reference: MetaCyc:Alpha-Amino-Acids
has_obo_namespace: chebi_ontology
has_related_synonym: an alpha-amino acid
id: CHEBI:78608
in_subset: 3 STAR

Axiom
annotated source: alpha-amino acid zwitterion
annotated property: database_cross_reference
annotated target: MetaCyc:Alpha-Amino-Acids
source: SUBMITTER

Axiom
annotated source: alpha-amino acid zwitterion
annotated property: has_related_synonym
annotated target: an alpha-amino acid
database_cross_reference: UniProt

carbohydrates and carbohydrate derivatives
type: Class
subclass of: organooxygen compound
definition: Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation.
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrates and derivatives
has_related_synonym: carbohydrates and their derivatives
id: CHEBI:78616
in_subset: 3 STAR

Axiom
annotated source: carbohydrates and carbohydrate derivatives
annotated property: has_related_synonym
annotated target: carbohydrates and derivatives
database_cross_reference: ChEBI

Axiom
annotated source: carbohydrates and carbohydrate derivatives
annotated property: has_related_synonym
annotated target: carbohydrates and their derivatives
database_cross_reference: ChEBI

fundamental metabolite
type: Class
subclass of: metabolite
definition: Any metabolite produced by all living cells.
has_obo_namespace: chebi_ontology
has_related_synonym: essential metabolite
has_related_synonym: essential metabolites
has_related_synonym: fundamental metabolites
id: CHEBI:78675
in_subset: 3 STAR

Axiom
annotated source: fundamental metabolite
annotated property: has_related_synonym
annotated target: essential metabolite
database_cross_reference: ChEBI

Axiom
annotated source: fundamental metabolite
annotated property: has_related_synonym
annotated target: essential metabolites
database_cross_reference: ChEBI

Axiom
annotated source: fundamental metabolite
annotated property: has_related_synonym
annotated target: fundamental metabolites
database_cross_reference: ChEBI

olefinic compound
type: Class
subclass of: organic molecular entity

trivalent inorganic anion
type: Class
subclass of: inorganic anion
definition: Any inorganic anion with a valency of three.
has_obo_namespace: chebi_ontology
has_related_synonym: trivalent inorganic anions
id: CHEBI:79387
in_subset: 3 STAR

Axiom
annotated source: trivalent inorganic anion
annotated property: has_related_synonym
annotated target: trivalent inorganic anions
database_cross_reference: ChEBI

divalent inorganic anion
type: Class
subclass of: inorganic anion
definition: Any inorganic anion with a valency of two.
has_obo_namespace: chebi_ontology
has_related_synonym: divalent inorganic anions
id: CHEBI:79388
in_subset: 3 STAR

Axiom
annotated source: divalent inorganic anion
annotated property: has_related_synonym
annotated target: divalent inorganic anions
database_cross_reference: ChEBI

monovalent inorganic anion
type: Class
subclass of: inorganic anion
definition: Any inorganic anion with a valency of one.
has_obo_namespace: chebi_ontology
has_related_synonym: monovalent inorganic anions
id: CHEBI:79389
in_subset: 3 STAR

Axiom
annotated source: monovalent inorganic anion
annotated property: has_related_synonym
annotated target: monovalent inorganic anions
database_cross_reference: ChEBI

Nodularin
type: Class
subclass of: ether

Peptidoglycan(N-acetyl-D-glucosamine)
type: Class
subclass of: polyol

Brevetoxin B
type: Class
subclass of: ciguatoxin

pheophytin
type: Class
subclass of: phorbines

diatomaceous earth
type: Class
subclass of: silicon dioxide
subclass of: mineral

elemental iron
type: Class
subclass of: iron molecular entity
subclass of: elemental molecular entity

iron(0)
type: Class
subclass of: elemental iron

crustacean metabolite
type: Class
subclass of: animal metabolite
definition: An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
has_obo_namespace: chebi_ontology
has_related_synonym: crustacean metabolites
id: CHEBI:83039
in_subset: 3 STAR

Axiom
annotated source: crustacean metabolite
annotated property: has_related_synonym
annotated target: crustacean metabolites
database_cross_reference: ChEBI

Daphnia magna metabolite
type: Class
subclass of: Daphnia metabolite
definition: A Daphnia metabolite produced by the species Daphnia magna.
has_obo_namespace: chebi_ontology
has_related_synonym: Daphnia magna metabolites
id: CHEBI:83056
in_subset: 3 STAR

Axiom
annotated source: Daphnia magna metabolite
annotated property: has_related_synonym
annotated target: Daphnia magna metabolites
database_cross_reference: ChEBI

Daphnia metabolite
type: Class
subclass of: crustacean metabolite
definition: A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
database_cross_reference: Wikipedia:Daphnia
has_obo_namespace: chebi_ontology
has_related_synonym: Daphnia metabolites
id: CHEBI:83057
in_subset: 3 STAR

Axiom
annotated source: Daphnia metabolite
annotated property: has_related_synonym
annotated target: Daphnia metabolites
database_cross_reference: ChEBI

chlorophyllide a(2-)
type: Class
subclass of: chlorophyllide(2-)

N-acylammonia
type: Class
subclass of: carboxamide

proteinogenic amino acid derivative
type: Class
subclass of: amino acid derivative

non-proteinogenic amino acid
type: Class
subclass of: amino acid

amino acid derivative
type: Class
subclass of: organonitrogen compound

non-proteinogenic alpha-amino acid
type: Class
subclass of: alpha-amino acid
subclass of: non-proteinogenic amino acid

pentose phosphate
type: Class
subclass of: phospho sugar
subclass of: pentose derivative

hydroxyindoles
type: Class
subclass of: indoles
subclass of: organic hydroxy compound
definition: Any member of the class of indoles carrying at least one hydroxy group.
has_obo_namespace: chebi_ontology
id: CHEBI:84729
in_subset: 3 STAR

algal metabolite
type: Class
subclass of: eukaryotic metabolite
definition: Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
has_obo_namespace: chebi_ontology
has_related_synonym: algal metabolites
id: CHEBI:84735
in_subset: 3 STAR

Axiom
annotated source: algal metabolite
annotated property: has_related_synonym
annotated target: algal metabolites
database_cross_reference: ChEBI

pyrite
type: Class
subclass of: sulfide mineral
subclass of: iron(2+) sulfides

metal allergen
type: Class
subclass of: metal atom

aromatic carboxylate
type: Class
subclass of: carboxylic acid anion

skatole
type: Class
subclass of: methylindole

cell
type: Class
subclass of: UBERON_0000061
subclass of: Restriction
  on property: only in taxon
  some values from: NCBITaxon_131567
disjoint with: GO_0031012
disjoint with: GO_0032991
disjoint with: GO_0043226
definition: A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
definition: A material entity that has a plasma membrane and results from cellular division.
database_cross_reference: CALOHA:TS-2035
database_cross_reference: FBbt:00007002
database_cross_reference: FMA:68646
database_cross_reference: GO:0005623
database_cross_reference: KUPO:0000002
database_cross_reference: MESH:D002477
database_cross_reference: VHOG:0001533
database_cross_reference: WBbt:0004017
database_cross_reference: XAO:0003012
in_subset: cellxgene subset
in_subset: upper level
comment: CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc.
comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).
comment: We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism.

Axiom
annotated source: cell
annotated property: definition
annotated target: A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CARO:mah

fibroblast neural crest derived
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: develops from
    some values from: migratory neural crest cell
subclass of: fibroblast
subclass of: UBERON_0010313
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
subclass of: Restriction
  on property: develops from
  some values from: migratory neural crest cell
definition: Any fibroblast that is deriived from the neural crest.

Axiom
annotated source: fibroblast neural crest derived
annotated property: definition
annotated target: Any fibroblast that is deriived from the neural crest.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

neuronal receptor cell
type: Class
equivalent class: Class
  intersection of: sensory receptor cell
  intersection of: CL_0000540
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: sensory neuron
subclass of: sensory receptor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
has_exact_synonym: neuronal receptor cell (sensu Animalia)
in_subset: cellxgene subset

early embryonic cell (metazoa)
type: Class
subclass of: CL_0002321
definition: A cell found in the embryo before the formation of all the gem layers is complete.

Axiom
annotated source: early embryonic cell (metazoa)
annotated property: definition
annotated target: A cell found in the embryo before the formation of all the gem layers is complete.
database_cross_reference: GOC:tfm

migratory cranial neural crest cell
type: Class
subclass of: migratory neural crest cell
definition: Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination.

Axiom
annotated source: migratory cranial neural crest cell
annotated property: definition
annotated target: Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination.
database_cross_reference: ZFA:0007091
database_cross_reference: https://orcid.org/0000-0001-5208-3432

migratory trunk neural crest cell
type: Class
subclass of: migratory neural crest cell
definition: Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination.

Axiom
annotated source: migratory trunk neural crest cell
annotated property: definition
annotated target: Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination.
database_cross_reference: ZFA:0007095
database_cross_reference: https://orcid.org/0000-0001-5208-3432

germ line stem cell
type: Class
equivalent class: Class
  intersection of: germ line cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: stem cell
subclass of: germ line cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0017145
definition: A stem cell that is the precursor of gametes.
database_cross_reference: FBbt:00004861
has_exact_synonym: germline stem cell

Axiom
annotated source: germ line stem cell
annotated property: subClassOf
annotated target: stem cell
is inferred: true

Axiom
annotated source: germ line stem cell
annotated property: definition
annotated target: A stem cell that is the precursor of gametes.
database_cross_reference: doi:10.1016/j.stem.2012.05.016

female germ cell
type: Class
equivalent class: Class
  intersection of: CL_0000586
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048477
subclass of: CL_0000586
subclass of: Restriction
  on property: capable of
  some values from: GO_0048477
definition: Female germ cell is a germ cell that supports female gamete production.
database_cross_reference: MA:0000388
database_cross_reference: VHOG:0001530
database_cross_reference: ncithesaurus:Egg
in_subset: cellxgene subset

Axiom
annotated source: female germ cell
annotated property: subClassOf
annotated target: CL_0000586
is inferred: true

Axiom
annotated source: female germ cell
annotated property: definition
annotated target: Female germ cell is a germ cell that supports female gamete production.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:11023867
database_cross_reference: PMID:20454446

female germ line stem cell
type: Class
equivalent class: Class
  intersection of: female germ cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: germ line stem cell
subclass of: female germ cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0017145
definition: A stem cell that is the precursor of female gametes.
database_cross_reference: FBbt:00004873

Axiom
annotated source: female germ line stem cell
annotated property: subClassOf
annotated target: germ line stem cell
is inferred: true

Axiom
annotated source: female germ line stem cell
annotated property: subClassOf
annotated target: female germ cell
is inferred: true

Axiom
annotated source: female germ line stem cell
annotated property: definition
annotated target: A stem cell that is the precursor of female gametes.
database_cross_reference: doi:10.1016/j.stem.2012.05.016

oocyte
type: Class
subclass of: female germ cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: participates in
  some values from: GO_0007143
subclass of: Restriction
  on property: only in taxon
  some values from: NCBITaxon_33208
definition: A female germ cell that has entered meiosis.
database_cross_reference: BTO:0000964
database_cross_reference: CALOHA:TS-0711
database_cross_reference: FBbt:00004886
database_cross_reference: FMA:18644
database_cross_reference: MESH:D009865
database_cross_reference: WBbt:0006797
has_related_synonym: oogonium
in_subset: cellxgene subset

Axiom
annotated source: oocyte
annotated property: subClassOf
annotated target: female germ cell
is inferred: true

Axiom
annotated source: oocyte
annotated property: definition
annotated target: A female germ cell that has entered meiosis.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

oogonial cell
type: Class
equivalent class: Class
  intersection of: female germ cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0000278
subclass of: female germ cell
subclass of: Restriction
  on property: develops from
  some values from: CL_0000670
subclass of: Restriction
  on property: capable of
  some values from: GO_0000278
definition: An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.
database_cross_reference: FMA:83673
in_subset: cellxgene subset

Axiom
annotated source: oogonial cell
annotated property: subClassOf
annotated target: female germ cell
is inferred: true

Axiom
annotated source: oogonial cell
annotated property: definition
annotated target: An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

egg cell
type: Class
subclass of: CL_0000675
subclass of: Restriction
  on property: participates in
  some values from: GO_0007143
subclass of: Restriction
  on property: develops from
  some values from: oocyte
definition: A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.
database_cross_reference: BTO:0000369
database_cross_reference: BTO:0003801
database_cross_reference: CALOHA:TS-2191
database_cross_reference: FBbt:00057012
database_cross_reference: FMA:67343
database_cross_reference: MESH:D010063
has_exact_synonym: mature oocyte
has_exact_synonym: ovum

Axiom
annotated source: egg cell
annotated property: subClassOf
annotated target: CL_0000675
is inferred: true

Axiom
annotated source: egg cell
annotated property: definition
annotated target: A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

smooth muscle cell neural crest derived
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: develops from
    some values from: migratory neural crest cell
subclass of: smooth muscle cell
subclass of: UBERON_0010313
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
subclass of: Restriction
  on property: develops from
  some values from: migratory neural crest cell
definition: A smooth muscle cell derived from the neural crest.

Axiom
annotated source: smooth muscle cell neural crest derived
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: smooth muscle cell neural crest derived
annotated property: definition
annotated target: A smooth muscle cell derived from the neural crest.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

neural crest derived neuron
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: develops from
    some values from: migratory neural crest cell
subclass of: CL_0000540
subclass of: UBERON_0010313
subclass of: Restriction
  on property: develops from
  some values from: migratory neural crest cell
subclass of: Restriction
  on property: develops from
  some values from: CL_0002676
has_exact_synonym: neuron neural crest derived

Axiom
annotated source: neural crest derived neuron
annotated property: subClassOf
annotated target: CL_0000540
is inferred: true

neuroblast (sensu Vertebrata)
type: Class
subclass of: non-terminally differentiated cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: only in taxon
  some values from: NCBITaxon 7742
definition: A cell that will develop into a neuron often after a migration phase.
database_cross_reference: BTO:0000930
database_cross_reference: FMA:70563
has_exact_synonym: neuroblast
in_subset: cellxgene subset

Axiom
annotated source: neuroblast (sensu Vertebrata)
annotated property: definition
annotated target: A cell that will develop into a neuron often after a migration phase.
database_cross_reference: GOC:NV
database_cross_reference: http://en.wikipedia.org/wiki/Neuroblast

stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: CL_0011115
subclass of: Restriction
  on property: in taxon
  some values from: NCBITaxon_33208
subclass of: Restriction
  on property: capable of
  some values from: GO_0017145
subclass of: Restriction
  on property: capable of
  some values from: GO_0030154
definition: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
present in taxon: NCBITaxon 9606
database_cross_reference: CALOHA:TS-2086
database_cross_reference: FMA:63368
has_exact_synonym: animal stem cell
in_subset: cellxgene subset
in_subset: general cell types upper slim
in_subset: human reference atlas
comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’.

Axiom
annotated source: stem cell
annotated property: definition
annotated target: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D013234

single fate stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001400
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: CL_0000723
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001400
subclass of: Restriction
  on property: capable of
  some values from: GO_0017145
definition: A stem cell that self-renews as well as give rise to a single mature cell type.
database_cross_reference: FMA:70569
has_exact_synonym: unipotent stem cell
has_exact_synonym: unipotential stem cell

Axiom
annotated source: single fate stem cell
annotated property: definition
annotated target: A stem cell that self-renews as well as give rise to a single mature cell type.
database_cross_reference: GOC:tfm

hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: CL_0000988
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: capable of
    some values from: GO_0002244
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048103
subclass of: CL_0000723
subclass of: CL_0000988
subclass of: CL_0008001
subclass of: CL_0011026
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: develops from
  some values from: CL_0000566
subclass of: Restriction
  on property: capable of
  some values from: GO_0002244
subclass of: Restriction
  on property: capable of
  some values from: GO_0048103
definition: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000725
database_cross_reference: CALOHA:TS-0448
database_cross_reference: FMA:86475
database_cross_reference: MESH:D006412
database_cross_reference: VHOG:0001485
has_exact_synonym: blood forming stem cell
has_exact_synonym: hemopoietic stem cell
has_related_synonym: HSC
has_related_synonym: colony forming unit hematopoietic
in_subset: blood and immune upper slim
in_subset: cellxgene subset
in_subset: human reference atlas
comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.

Axiom
annotated source: hematopoietic stem cell
annotated property: subClassOf
annotated target: CL_0000988
is inferred: true

Axiom
annotated source: hematopoietic stem cell
annotated property: definition
annotated target: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
database_cross_reference: GOC:add
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: PMID:19022770
database_cross_reference: http://en.wikipedia.org/wiki/Hematopoietic_stem_cell

Axiom
annotated source: hematopoietic stem cell
annotated property: has_related_synonym
annotated target: HSC
has_synonym_type: OMO_0003000

erythroid progenitor cell
type: Class
subclass of: CL_0000764
subclass of: CL_0000839
subclass of: Restriction
  on property: develops from
  some values from: megakaryocyte-erythroid progenitor cell
definition: A progenitor cell committed to the erythroid lineage.
database_cross_reference: BTO:0004911
has_related_synonym: BFU-E
has_related_synonym: CFU-E
has_related_synonym: blast forming unit erythroid
has_related_synonym: burst forming unit erythroid
has_related_synonym: colony forming unit erythroid
has_related_synonym: erythroid stem cell
in_subset: blood and immune upper slim
in_subset: cellxgene subset

Axiom
annotated source: erythroid progenitor cell
annotated property: subClassOf
annotated target: CL_0000839
is inferred: true

Axiom
annotated source: erythroid progenitor cell
annotated property: definition
annotated target: A progenitor cell committed to the erythroid lineage.
database_cross_reference: GOC:add
database_cross_reference: ISBN:0721601464

Axiom
annotated source: erythroid progenitor cell
annotated property: has_related_synonym
annotated target: BFU-E
has_synonym_type: OMO_0003000

Axiom
annotated source: erythroid progenitor cell
annotated property: has_related_synonym
annotated target: CFU-E
has_synonym_type: OMO_0003000

germ line cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0022414
definition: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
in_subset: general cell types upper slim
in_subset: upper level
comment: Originally this term had some plant germ line cell children.

Axiom
annotated source: germ line cell
annotated property: definition
annotated target: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

multi fate stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001402
  intersection of: Restriction
    on property: capable of
    some values from: GO_0017145
subclass of: stem cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001402
subclass of: Restriction
  on property: capable of
  some values from: GO_0017145
definition: A stem cell that can give rise to multiple lineages of cells.
database_cross_reference: FMA:84789
has_exact_synonym: multi-fate stem cell
has_exact_synonym: multifate stem cell
has_exact_synonym: multipotent cell
has_exact_synonym: multipotent stem cell

Axiom
annotated source: multi fate stem cell
annotated property: definition
annotated target: A stem cell that can give rise to multiple lineages of cells.
database_cross_reference: GOC:add

common myeloid progenitor
type: Class
subclass of: CL_0002032
disjoint with: megakaryocyte-erythroid progenitor cell
definition: A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0004730
has_exact_synonym: common myeloid precursor
has_related_synonym: CFU-GEMM
has_related_synonym: CFU-S
has_related_synonym: CMP
has_related_synonym: colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte
has_related_synonym: multipotential myeloid stem cell
has_related_synonym: myeloid stem cell
has_related_synonym: pluripotent stem cell (bone marrow)
in_subset: cellxgene subset
in_subset: human reference atlas
comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059).

Axiom
annotated source: common myeloid progenitor
annotated property: subClassOf
annotated target: CL_0002032
is inferred: true

Axiom
annotated source: common myeloid progenitor
annotated property: definition
annotated target: A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages.
database_cross_reference: GOC:add
database_cross_reference: ISBN:0878932437
database_cross_reference: MESH:D023461

Axiom
annotated source: common myeloid progenitor
annotated property: has_related_synonym
annotated target: CFU-GEMM
database_cross_reference: ISBN:0878932437
has_synonym_type: OMO_0003000

Axiom
annotated source: common myeloid progenitor
annotated property: has_related_synonym
annotated target: CFU-S
database_cross_reference: ISBN:0878932437
has_synonym_type: OMO_0003000

Axiom
annotated source: common myeloid progenitor
annotated property: has_related_synonym
annotated target: CMP
database_cross_reference: ISBN:0878932437
has_synonym_type: OMO_0003000

Axiom
annotated source: common myeloid progenitor
annotated property: has_related_synonym
annotated target: colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte
database_cross_reference: ISBN:0878932437

Axiom
annotated source: common myeloid progenitor
annotated property: has_related_synonym
annotated target: multipotential myeloid stem cell
database_cross_reference: ISBN:0878932437

Axiom
annotated source: common myeloid progenitor
annotated property: has_related_synonym
annotated target: myeloid stem cell
database_cross_reference: ISBN:0878932437

Axiom
annotated source: common myeloid progenitor
annotated property: has_related_synonym
annotated target: pluripotent stem cell (bone marrow)
database_cross_reference: ISBN:0878932437

megakaryocyte-erythroid progenitor cell
type: Class
equivalent class: Class
  intersection of: CL_0002032
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030218
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030219
subclass of: CL_0000763
subclass of: CL_0002032
subclass of: CL_0011026
subclass of: Restriction
  on property: develops from
  some values from: common myeloid progenitor
subclass of: Restriction
  on property: capable of
  some values from: GO_0030218
subclass of: Restriction
  on property: capable of
  some values from: GO_0030219
definition: A progenitor cell committed to the megakaryocyte and erythroid lineages.
present in taxon: NCBITaxon 9606
has_exact_synonym: CFU-EM
has_exact_synonym: CFU-MegE
has_exact_synonym: MEP
has_exact_synonym: Meg/E progenitor
has_exact_synonym: colony forming unit erythroid megakaryocyte
has_exact_synonym: megakaryocyte/erythrocyte progenitor
has_exact_synonym: megakaryocyte/erythroid progenitor cell
in_subset: cellxgene subset
in_subset: human reference atlas
comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2.

Axiom
annotated source: megakaryocyte-erythroid progenitor cell
annotated property: subClassOf
annotated target: CL_0002032
is inferred: true

Axiom
annotated source: megakaryocyte-erythroid progenitor cell
annotated property: definition
annotated target: A progenitor cell committed to the megakaryocyte and erythroid lineages.
database_cross_reference: GOC:add
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D055015
database_cross_reference: PMID:16647566
database_cross_reference: http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell

totipotent stem cell
type: Class
subclass of: CL_0000723
definition: A stem cell from which all cells of the body can form.
database_cross_reference: FMA:84790
database_cross_reference: MESH:D039901
has_exact_synonym: totipotential stem cell

Axiom
annotated source: totipotent stem cell
annotated property: definition
annotated target: A stem cell from which all cells of the body can form.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm

non-terminally differentiated cell
type: Class
subclass of: CL_0011115
subclass of: Restriction
  on property: capable of
  some values from: GO_0030154
definition: A precursor cell with a limited number of potential fates.
database_cross_reference: BTO:0000125
database_cross_reference: FMA:84782
has_exact_synonym: blast cell
in_subset: cellxgene subset
comment: define using PATO mulit-potent or oligopotent?

Axiom
annotated source: non-terminally differentiated cell
annotated property: definition
annotated target: A precursor cell with a limited number of potential fates.
database_cross_reference: SANBI:mhl

myoblast
type: Class
subclass of: CL_0000680
definition: A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair.
database_cross_reference: BTO:0000222
database_cross_reference: CALOHA:TS-0650
database_cross_reference: FBbt:00005083
database_cross_reference: FMA:70335
database_cross_reference: VHOG:0001529

Axiom
annotated source: myoblast
annotated property: definition
annotated target: A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D032446
database_cross_reference: PMID:21849021

fibroblast
type: Class
subclass of: CL_0002320
subclass of: Restriction
  on property: develops from
  some values from: mesenchymal stem cell
definition: A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000452
database_cross_reference: CALOHA:TS-0362
database_cross_reference: FMA:63877
database_cross_reference: NCIT:C12482
database_cross_reference: VHOG:0001482
in_subset: cellxgene subset
in_subset: general cell types upper slim
in_subset: human reference atlas
comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

Axiom
annotated source: fibroblast
annotated property: definition
annotated target: A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
database_cross_reference: ISBN:0517223651
database_cross_reference: MESH:D005347
database_cross_reference: http://en.wikipedia.org/wiki/Fibroblast

chondroblast
type: Class
subclass of: non-terminally differentiated cell
subclass of: CL_0002320
subclass of: Restriction
  on property: develops from
  some values from: CL_0007009
subclass of: Restriction
  on property: produces
  some values from: UBERON_0002418
definition: Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell.
database_cross_reference: BTO:0003607
database_cross_reference: FMA:66783
has_exact_synonym: chrondoplast

Axiom
annotated source: chondroblast
annotated property: definition
annotated target: Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell.
database_cross_reference: GOC:tfm
database_cross_reference: GO_REF:0000034
database_cross_reference: ISBN:0618947256

ciliated cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has part
    some values from: GO_0005929
subclass of: cell
subclass of: PR_000050567
subclass of: Restriction
  on property: has part
  some values from: GO_0005929
definition: A cell that has a filiform extrusion of the cell surface.
database_cross_reference: VHOG:0001532
database_cross_reference: XAO:0000031
in_subset: cellxgene subset

Axiom
annotated source: ciliated cell
annotated property: definition
annotated target: A cell that has a filiform extrusion of the cell surface.
database_cross_reference: GOC:tfm

epithelial cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000483
disjoint with: CL_0000738
definition: A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000414
database_cross_reference: CALOHA:TS-2026
database_cross_reference: CARO:0000077
database_cross_reference: FBbt:00000124
database_cross_reference: FMA:66768
database_cross_reference: WBbt:0003672
has_exact_synonym: epitheliocyte
in_subset: cellxgene subset
in_subset: general cell types upper slim
in_subset: human reference atlas

Axiom
annotated source: epithelial cell
annotated property: definition
annotated target: A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D004847

ciliated epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: has part
    some values from: GO_0005929
subclass of: ciliated cell
subclass of: epithelial cell
subclass of: Restriction
  on property: has part
  some values from: GO_0005929
definition: An epithelial cell that has a cilia.
database_cross_reference: FMA:70605
in_subset: cellxgene subset

Axiom
annotated source: ciliated epithelial cell
annotated property: definition
annotated target: An epithelial cell that has a cilia.
database_cross_reference: GOC:tfm

duct epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000058
subclass of: epithelial cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000058
definition: An epithelial cell that is part of a duct.
in_subset: cellxgene subset

Axiom
annotated source: duct epithelial cell
annotated property: definition
annotated target: An epithelial cell that is part of a duct.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

branched duct epithelial cell
type: Class
subclass of: duct epithelial cell

blood vessel endothelial cell
type: Class
equivalent class: Class
  intersection of: squamous epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004638
subclass of: squamous epithelial cell
subclass of: CL_0002139
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004638
subclass of: Restriction
  on property: develops from
  some values from: CL_0002546
definition: An endothelial cell that lines the vasculature.
present in taxon: NCBITaxon 9606
has_exact_synonym: cuboidal endothelial cell of vascular tree
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: blood vessel endothelial cell
annotated property: subClassOf
annotated target: squamous epithelial cell
is inferred: true

Axiom
annotated source: blood vessel endothelial cell
annotated property: definition
annotated target: An endothelial cell that lines the vasculature.
database_cross_reference: GOC:tfm

columnar/cuboidal epithelial cell
type: Class
subclass of: epithelial cell
definition: A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
present in taxon: NCBITaxon 9606
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: columnar/cuboidal epithelial cell
annotated property: definition
annotated target: A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
database_cross_reference: GO:0002065
database_cross_reference: https://orcid.org/0000-0001-5208-3432

squamous epithelial cell
type: Class
subclass of: epithelial cell
database_cross_reference: CALOHA:TS-1249
in_subset: cellxgene subset

mesothelial cell
type: Class
subclass of: squamous epithelial cell
subclass of: lining cell
subclass of: CL_0002078
subclass of: Restriction
  on property: develops from
  some values from: mesodermal cell
definition: A flattened epithelial cell of mesenchymal origin that lines the serous cavity.
present in taxon: NCBITaxon 9606
database_cross_reference: FMA:66773
has_exact_synonym: mesotheliocyte
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: mesothelial cell
annotated property: definition
annotated target: A flattened epithelial cell of mesenchymal origin that lines the serous cavity.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

circulating cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000179
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000179
definition: A cell which moves among different tissues of the body, via blood, lymph, or other medium.

Axiom
annotated source: circulating cell
annotated property: definition
annotated target: A cell which moves among different tissues of the body, via blood, lymph, or other medium.
database_cross_reference: GOC:add

blood cell
type: Class
equivalent class: Class
  intersection of: CL_0000988
  intersection of: Restriction
    on property: capable of
    some values from: GO_0008015
subclass of: CL_0000988
subclass of: Restriction
  on property: capable of
  some values from: GO_0008015
definition: A cell found predominately in the blood.
database_cross_reference: FMA:62844
database_cross_reference: MESH:D001773
in_subset: cellxgene subset
in_subset: general cell types upper slim

Axiom
annotated source: blood cell
annotated property: subClassOf
annotated target: CL_0000988
is inferred: true

Axiom
annotated source: blood cell
annotated property: definition
annotated target: A cell found predominately in the blood.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm

epithelial cell of lung
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002048
subclass of: epithelial cell
subclass of: UBERON_0004119
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000115
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002048
definition: An epithelial cell of the lung.
database_cross_reference: BTO:0004299
has_exact_synonym: lung epithelial cell
in_subset: cellxgene subset

Axiom
annotated source: epithelial cell of lung
annotated property: definition
annotated target: An epithelial cell of the lung.
database_cross_reference: https://orcid.org/0000-0001-5208-3432

epithelial cell of pancreas
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: epithelial cell
subclass of: UBERON_0004119
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001264
subclass of: Restriction
  on property: develops from
  some values from: endodermal cell
definition: An epithelial cell of the pancreas.
database_cross_reference: BTO:0000028
has_exact_synonym: pancreas epithelial cell
has_exact_synonym: pancreatic epithelial cell

Axiom
annotated source: epithelial cell of pancreas
annotated property: definition
annotated target: An epithelial cell of the pancreas.
database_cross_reference: GOC:tfm

neuron associated cell
type: Class
subclass of: CL_0002319
subclass of: UBERON_0004121
subclass of: Restriction
  on property: develops from
  some values from: neurectodermal cell
in_subset: cellxgene subset

sensory epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: epithelial cell
subclass of: sensory receptor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
definition: A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.
has_broad_synonym: neuroepithelial cell
database_cross_reference: BTO:0004301
comment: The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710).

Axiom
annotated source: sensory epithelial cell
annotated property: definition
annotated target: A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: ISBN:0721662544

interneuron
type: Class
subclass of: CL_0000540
definition: Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0003811
database_cross_reference: FBbt:00005125
database_cross_reference: FMA:67313
database_cross_reference: WBbt:0005113
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: interneuron
annotated property: definition
annotated target: Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D007395

motor neuron
type: Class
subclass of: CL_0000527
definition: An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000312
database_cross_reference: FBbt:00005123
database_cross_reference: FMA:83617
database_cross_reference: WBbt:0005409
has_exact_synonym: motoneuron
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: motor neuron
annotated property: definition
annotated target: An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.
database_cross_reference: MESH:D009046
database_cross_reference: PMID:16875686

sensory neuron
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: CL_0000526
subclass of: CL_0000540
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
definition: Any neuron having a sensory function; an afferent neuron conveying sensory impulses.
database_cross_reference: BTO:0001037
database_cross_reference: FBbt:00005124
database_cross_reference: FMA:84649
database_cross_reference: MESH:D011984
database_cross_reference: WBbt:0005759

Axiom
annotated source: sensory neuron
annotated property: definition
annotated target: Any neuron having a sensory function; an afferent neuron conveying sensory impulses.
database_cross_reference: ISBN:0721662544

autonomic neuron
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0002410
subclass of: CL_2000032
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0002410
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)
definition: A neuron whose cell body is within an autonomic ganglion.
database_cross_reference: FMA:80121

Axiom
annotated source: autonomic neuron
annotated property: definition
annotated target: A neuron whose cell body is within an autonomic ganglion.
database_cross_reference: GOC:tfm

cholinergic neuron
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: capable of
    some values from: GO_0014055
subclass of: secretory cell
subclass of: CL_0000540
subclass of: Restriction
  on property: capable of
  some values from: GO_0014055
definition: A neuron that uses acetylcholine as a vesicular neurotransmitter.
database_cross_reference: BTO:0004902
database_cross_reference: FBbt:00007173
database_cross_reference: FMA:84796
database_cross_reference: MESH:D059329
database_cross_reference: WBbt:0006840

Axiom
annotated source: cholinergic neuron
annotated property: definition
annotated target: A neuron that uses acetylcholine as a vesicular neurotransmitter.
database_cross_reference: GOC:tfm

endothelial cell
type: Class
subclass of: lining cell
subclass of: CL_0002078
definition: An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0001176
database_cross_reference: CALOHA:TS-0278
database_cross_reference: FMA:66772
has_exact_synonym: endotheliocyte
in_subset: cellxgene subset
in_subset: human reference atlas
comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].

Axiom
annotated source: endothelial cell
annotated property: definition
annotated target: An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D042783
database_cross_reference: PMID:21275341
database_cross_reference: http://en.wikipedia.org/wiki/Endothelial_cell
database_cross_reference: https://sourceforge.net/tracker/

CNS neuron (sensu Vertebrata)
type: Class
subclass of: CL_0000540
subclass of: UBERON_0004121
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001017
subclass of: Restriction
  on property: develops from
  some values from: neuroblast (sensu Vertebrata)

glial cell
type: Class
subclass of: neuron associated cell
definition: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.
database_cross_reference: BTO:0002606
database_cross_reference: CALOHA:TS-0415
database_cross_reference: FBbt:00005144
database_cross_reference: FMA:54536
has_exact_synonym: neuroglial cell
has_related_synonym: neuroglia
in_subset: cellxgene subset
in_subset: general cell types upper slim
comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571

Axiom
annotated source: glial cell
annotated property: definition
annotated target: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.
database_cross_reference: MESH:D009457

neurectodermal cell
type: Class
subclass of: ectodermal cell
definition: Ectoderm destined to be nervous tissue.
has_exact_synonym: neurectoderm cell

Axiom
annotated source: neurectodermal cell
annotated property: definition
annotated target: Ectoderm destined to be nervous tissue.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:068340007X

mesenchymal stem cell
type: Class
subclass of: multi fate stem cell
subclass of: CL_0002320
definition: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
database_cross_reference: BTO:0002625
database_cross_reference: BTO:0003298
database_cross_reference: FMA:70546
has_narrow_synonym: bone marrow stromal cells
has_narrow_synonym: colony-forming unit-fibroblast
has_narrow_synonym: marrow stromal cells
has_related_synonym: BMSC
has_related_synonym: CFU-F
has_related_synonym: MSC
has_related_synonym: mesenchymal precursor cell
has_related_synonym: mesenchymal progenitor cells
has_related_synonym: mesenchymal stem cell
has_related_synonym: mesenchymal stromal cell
has_related_synonym: mesenchymal stromal cells
has_related_synonym: stem cells, mesenchymal
in_subset: cellxgene subset
comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.

Axiom
annotated source: mesenchymal stem cell
annotated property: subClassOf
annotated target: CL_0002320
is inferred: true

Axiom
annotated source: mesenchymal stem cell
annotated property: definition
annotated target: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
database_cross_reference: FB:ma
database_cross_reference: GOC:dsd
database_cross_reference: PMCID:PMC2613570
database_cross_reference: PMID:10102814
database_cross_reference: PMID:16923606
database_cross_reference: PMID:17986482
database_cross_reference: PMID:19960544
database_cross_reference: http://en.wikipedia.org/wiki/Mesenchymal_stem_cell
database_cross_reference: http://www.copewithcytokines.de/cope.cgi

Axiom
annotated source: mesenchymal stem cell
annotated property: has_narrow_synonym
annotated target: marrow stromal cells
database_cross_reference: PMID:11378515

Axiom
annotated source: mesenchymal stem cell
annotated property: has_related_synonym
annotated target: BMSC
has_synonym_type: OMO_0003000

Axiom
annotated source: mesenchymal stem cell
annotated property: has_related_synonym
annotated target: CFU-F
has_synonym_type: OMO_0003000

Axiom
annotated source: mesenchymal stem cell
annotated property: has_related_synonym
annotated target: MSC
database_cross_reference: PMID:11378515
has_synonym_type: OMO_0003000

Axiom
annotated source: mesenchymal stem cell
annotated property: has_related_synonym
annotated target: mesenchymal progenitor cells
database_cross_reference: MESH:D044982
has_synonym_type: plural form

Axiom
annotated source: mesenchymal stem cell
annotated property: has_related_synonym
annotated target: mesenchymal stromal cells
has_synonym_type: plural form

Axiom
annotated source: mesenchymal stem cell
annotated property: has_related_synonym
annotated target: stem cells, mesenchymal
database_cross_reference: MESH:D044982
has_synonym_type: plural form

adipocyte
type: Class
subclass of: stuff accumulating cell
subclass of: CL_0002320
subclass of: Restriction
  on property: develops from
  some values from: mesenchymal stem cell
definition: A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000443
database_cross_reference: CALOHA:TS-0012
database_cross_reference: FMA:63880
has_exact_synonym: adipose cell
has_exact_synonym: fat cell
in_subset: cellxgene subset
in_subset: general cell types upper slim
in_subset: human reference atlas

Axiom
annotated source: adipocyte
annotated property: definition
annotated target: A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.
database_cross_reference: MESH:D017667

chondrocyte
type: Class
subclass of: glycosaminoglycan secreting cell
subclass of: CL_0000667
subclass of: Restriction
  on property: located in
  some values from: UBERON_0002418
subclass of: Restriction
  on property: develops from
  some values from: chondroblast
definition: Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell.
database_cross_reference: BTO:0000249
database_cross_reference: CALOHA:TS-0138
database_cross_reference: FMA:66782
has_exact_synonym: cartilage cell
in_subset: cellxgene subset

Axiom
annotated source: chondrocyte
annotated property: definition
annotated target: Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell.
database_cross_reference: GO_REF:0000034
database_cross_reference: MESH:D019902

pigment cell
type: Class
subclass of: stuff accumulating cell
definition: A pigment cell is a cell that contains pigment granules.
database_cross_reference: VHOG:0001678
has_exact_synonym: chromatocyte
has_exact_synonym: chromatophore

Axiom
annotated source: pigment cell
annotated property: definition
annotated target: A pigment cell is a cell that contains pigment granules.
database_cross_reference: GOC:tfm

visual pigment cell
type: Class
subclass of: pigment cell
has_broad_synonym: pigment cell

glandular epithelial cell
type: Class
subclass of: epithelial cell
subclass of: secretory cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0006799
definition: A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules.
database_cross_reference: CALOHA:TS-2085
database_cross_reference: FMA:86494
in_subset: cellxgene subset

Axiom
annotated source: glandular epithelial cell
annotated property: definition
annotated target: A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules.
database_cross_reference: GOC:tfm

secretory cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0032940
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0032940
definition: A cell that specializes in controlled release of one or more substances.
database_cross_reference: BTO:0003659
database_cross_reference: FMA:86916
in_subset: cellxgene subset

Axiom
annotated source: secretory cell
annotated property: definition
annotated target: A cell that specializes in controlled release of one or more substances.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

exocrine cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002365
subclass of: secretory cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002365
definition: A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.
database_cross_reference: FMA:16014
in_subset: general cell types upper slim

Axiom
annotated source: exocrine cell
annotated property: definition
annotated target: A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.
database_cross_reference: ISBN:0198547684

glycosaminoglycan secreting cell
type: Class
subclass of: extracellular matrix secreting cell
subclass of: CL_0000447
definition: A cell that secretes glycosaminoglycans.
has_exact_synonym: GAG secreting cell
has_narrow_synonym: hyaluronic acid secreting cell

Axiom
annotated source: glycosaminoglycan secreting cell
annotated property: definition
annotated target: A cell that secretes glycosaminoglycans.
database_cross_reference: GOC:tfm

protein secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0009306
subclass of: secretory cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0009306

seromucus secreting cell
type: Class
subclass of: secretory cell

endocrine cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: Class
      intersection of: GO_0046879
      intersection of: Restriction
        on property: has target end location
        some values from: UBERON_0001009
subclass of: secretory cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000949
subclass of: Restriction
  on property: capable of
  some values from: Class
    intersection of: GO_0046879
    intersection of: Restriction
      on property: has target end location
      some values from: UBERON_0001009
definition: A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
present in taxon: NCBITaxon 9606
database_cross_reference: FMA:83809
has_exact_synonym: endocrinocyte
in_subset: cellxgene subset
in_subset: general cell types upper slim
in_subset: human reference atlas

Axiom
annotated source: endocrine cell
annotated property: definition
annotated target: A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
database_cross_reference: MESH:D055098

enteroendocrine cell
type: Class
subclass of: glandular epithelial cell
subclass of: endocrine cell
definition: An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas.
database_cross_reference: BTO:0003865
database_cross_reference: FMA:62930
database_cross_reference: MESH:D019858
in_subset: cellxgene subset

Axiom
annotated source: enteroendocrine cell
annotated property: definition
annotated target: An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas.
database_cross_reference: GOC:tfm
database_cross_reference: SANBI:mhl

neuroendocrine cell
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: capable of
    some values from: GO_0046879
subclass of: endocrine cell
subclass of: CL_0000527
subclass of: CL_0000710
subclass of: Restriction
  on property: capable of
  some values from: GO_0046879
definition: A neuron that is capable of some hormone secretion in response to neuronal signals.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0002691
database_cross_reference: FBbt:00005130
database_cross_reference: FMA:83810
has_related_synonym: neurosecretory cell
has_related_synonym: neurosecretory neuron
in_subset: cellxgene subset
in_subset: human reference atlas
comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron.

Axiom
annotated source: neuroendocrine cell
annotated property: definition
annotated target: A neuron that is capable of some hormone secretion in response to neuronal signals.
database_cross_reference: MESH:D055099

Axiom
annotated source: neuroendocrine cell
annotated property: comment
annotated target: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron.
database_cross_reference: PMID:5342440
database_cross_reference: https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073

peptide hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030072
subclass of: secretory cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0030072

insulin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030073
subclass of: protein secreting cell
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0030073
database_cross_reference: BTO:0000783

type B pancreatic cell
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000006
  intersection of: Restriction
    on property: capable of
    some values from: GO_0030073
subclass of: enteroendocrine cell
subclass of: insulin secreting cell
subclass of: CL_0008024
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000006
subclass of: Restriction
  on property: develops from
  some values from: CL_0002351
subclass of: Restriction
  on property: capable of
  some values from: GO_0030073
definition: A cell that secretes insulin and is located towards the center of the islets of Langerhans.
present in taxon: NCBITaxon 9606
has_broad_synonym: beta cell
database_cross_reference: BTO:0000783
database_cross_reference: EV:0200009
database_cross_reference: FMA:70586
database_cross_reference: MA:0002419
database_cross_reference: ncithesaurus:Beta_Cell
has_exact_synonym: B-cell of pancreatic islet
has_exact_synonym: beta cell of pancreatic islet
has_exact_synonym: insulin-secreting cell
has_exact_synonym: pancreatic B cell
has_exact_synonym: pancreatic B-cell
has_exact_synonym: pancreatic beta cell
has_exact_synonym: pancreatic islet core
has_exact_synonym: type B enteroendocrine cell
has_related_synonym: beta cell islet
in_subset: cellxgene subset
in_subset: human reference atlas
comment: Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.

Axiom
annotated source: type B pancreatic cell
annotated property: subClassOf
annotated target: enteroendocrine cell
is inferred: true

Axiom
annotated source: type B pancreatic cell
annotated property: subClassOf
annotated target: insulin secreting cell
is inferred: true

Axiom
annotated source: type B pancreatic cell
annotated property: definition
annotated target: A cell that secretes insulin and is located towards the center of the islets of Langerhans.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: http://en.wikipedia.org/wiki/Pancreatic_b_cell

Axiom
annotated source: type B pancreatic cell
annotated property: has_broad_synonym
annotated target: beta cell
database_cross_reference: ZFA:0009102

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: B-cell of pancreatic islet
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: beta cell of pancreatic islet
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: insulin-secreting cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: pancreatic B-cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: pancreatic beta cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: pancreatic islet core
database_cross_reference: MA:0002419

Axiom
annotated source: type B pancreatic cell
annotated property: has_exact_synonym
annotated target: type B enteroendocrine cell
database_cross_reference: FMA:70586

Axiom
annotated source: type B pancreatic cell
annotated property: has_related_synonym
annotated target: beta cell islet
database_cross_reference: MA:0002419

glucagon secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070091
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0070091
definition: A cell that secretes glucagon.
database_cross_reference: FMA:84045
has_exact_synonym: glucagon-secreting cell

Axiom
annotated source: glucagon secreting cell
annotated property: definition
annotated target: A cell that secretes glucagon.
database_cross_reference: GOC:tfm

pancreatic A cell
type: Class
equivalent class: Class
  intersection of: CL_0002067
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: CL_0002067
subclass of: CL_0008024
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000006
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001264
subclass of: Restriction
  on property: develops from
  some values from: CL_0002351
subclass of: Restriction
  on property: capable of
  some values from: GO_0070091
definition: A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000990
database_cross_reference: FMA:70585
database_cross_reference: MESH:D050416
has_exact_synonym: alpha cell of islet of Langerhans
has_exact_synonym: pancreatic alpha cell
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: pancreatic A cell
annotated property: definition
annotated target: A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

somatostatin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070253
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0070253

pancreatic D cell
type: Class
equivalent class: Class
  intersection of: CL_0000502
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001264
subclass of: CL_0000502
subclass of: CL_0008024
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000006
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001264
subclass of: Restriction
  on property: develops from
  some values from: CL_0002351
definition: A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000803
database_cross_reference: FMA:70587
has_exact_synonym: D-cell of pancreatic islet
has_exact_synonym: delta cell of islet
has_exact_synonym: delta cell of pancreatic islet
has_exact_synonym: pancreatic D-cell
has_exact_synonym: pancreatic delta cell
has_exact_synonym: somatostatin-secreting pancreatic cell
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: pancreatic D cell
annotated property: definition
annotated target: A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.
database_cross_reference: FMA:0517223651
database_cross_reference: GOC:tfm

steroid hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0035929
subclass of: secretory cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0035929

hepatocyte
type: Class
subclass of: epithelial cell
subclass of: CL_0000417
subclass of: UBERON_0004119
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002107
subclass of: Restriction
  on property: develops from
  some values from: CL_0005026
subclass of: Restriction
  on property: capable of
  some values from: GO_0006699
subclass of: Restriction
  on property: capable of
  some values from: GO_0044237
subclass of: Restriction
  on property: capable of
  some values from: GO_0098754
definition: The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000575
database_cross_reference: CALOHA:TS-0454
database_cross_reference: FMA:14515
in_subset: cellxgene subset
in_subset: human reference atlas
comment: Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive.

Axiom
annotated source: hepatocyte
annotated property: definition
annotated target: The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0412046911
database_cross_reference: MESH:D022781
database_cross_reference: PMID:19717280
database_cross_reference: http://en.wikipedia.org/wiki/Hepatocyte

contractile cell
type: Class
subclass of: cell
definition: A cell whose primary function is to shorten.
in_subset: cellxgene subset

Axiom
annotated source: contractile cell
annotated property: definition
annotated target: A cell whose primary function is to shorten.
database_cross_reference: FB:ma

muscle cell
type: Class
subclass of: contractile cell
subclass of: electrically responsive cell
subclass of: UBERON_0004120
subclass of: Restriction
  on property: develops from
  some values from: myoblast
definition: A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
database_cross_reference: BTO:0000888
database_cross_reference: BTO:0000902
database_cross_reference: CALOHA:TS-2032
database_cross_reference: FBbt:00005074
database_cross_reference: FMA:67328
database_cross_reference: WBbt:0003675
has_exact_synonym: muscle fiber
has_exact_synonym: myocyte
in_subset: cellxgene subset

Axiom
annotated source: muscle cell
annotated property: definition
annotated target: A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
database_cross_reference: MESH:D032342

cell of skeletal muscle
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001134
subclass of: cell
subclass of: UBERON_0004120
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001134
definition: A somatic cell located in skeletal muscle.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0004392
database_cross_reference: CALOHA:TS-2158
database_cross_reference: FMA:9727
has_exact_synonym: skeletal muscle cell
in_subset: cellxgene subset
in_subset: general cell types upper slim
in_subset: human reference atlas

Axiom
annotated source: cell of skeletal muscle
annotated property: definition
annotated target: A somatic cell located in skeletal muscle.
database_cross_reference: GOC:tfm

smooth muscle cell
type: Class
subclass of: CL_0008000
subclass of: CL_0008007
subclass of: Restriction
  on property: develops from
  some values from: CL_0000514
definition: A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).
present in taxon: NCBITaxon 9606
has_broad_synonym: non-striated muscle cell
database_cross_reference: BTO:0004576
database_cross_reference: CALOHA:TS-2159
database_cross_reference: FMA:14072
has_exact_synonym: SMCs
has_exact_synonym: myocytes, smooth muscle
has_exact_synonym: smooth muscle fiber
in_subset: cellxgene subset
in_subset: general cell types upper slim
in_subset: human reference atlas

Axiom
annotated source: smooth muscle cell
annotated property: definition
annotated target: A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).
database_cross_reference: MESH:D032389
database_cross_reference: PMID:9315361
database_cross_reference: http://en.wikipedia.org/wiki/Smooth_muscle_cell

Axiom
annotated source: smooth muscle cell
annotated property: has_exact_synonym
annotated target: SMCs
database_cross_reference: PMID:9315361

Axiom
annotated source: smooth muscle cell
annotated property: has_exact_synonym
annotated target: myocytes, smooth muscle
database_cross_reference: MESH:D032389

sensory receptor cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001032
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001032
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
definition: A cell that is capable of detection of a stimulus involved in sensory perception.
database_cross_reference: MESH:D011984
has_exact_synonym: receptor cell

chemoreceptor cell
type: Class
equivalent class: Class
  intersection of: sensory receptor cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050907
subclass of: sensory receptor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0050907
definition: A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.

Axiom
annotated source: chemoreceptor cell
annotated property: definition
annotated target: A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.
database_cross_reference: MESH:D002628

photoreceptor cell
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050962
subclass of: neuronal receptor cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0050962
definition: A cell specialized to detect and transduce light.
database_cross_reference: BTO:0001060
database_cross_reference: CALOHA:TS-0868
database_cross_reference: FMA:86740
in_subset: cellxgene subset

Axiom
annotated source: photoreceptor cell
annotated property: subClassOf
annotated target: neuronal receptor cell
is inferred: true

Axiom
annotated source: photoreceptor cell
annotated property: definition
annotated target: A cell specialized to detect and transduce light.
database_cross_reference: MESH:D010786

electrically active cell
type: Class
subclass of: cell
definition: A cell whose function is determined by the generation or the reception of an electric signal.

Axiom
annotated source: electrically active cell
annotated property: definition
annotated target: A cell whose function is determined by the generation or the reception of an electric signal.
database_cross_reference: FB:ma

lining cell
type: Class
subclass of: barrier cell
definition: A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism.
has_exact_synonym: boundary cell

Axiom
annotated source: lining cell
annotated property: definition
annotated target: A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism.
database_cross_reference: JB:jb

synovial cell
type: Class
subclass of: lining cell
subclass of: CL_0002078
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002217
definition: A cell located in the synovial joint.
database_cross_reference: CALOHA:TS-0995
has_exact_synonym: synoviocyte

Axiom
annotated source: synovial cell
annotated property: subClassOf
annotated target: CL_0002078
is inferred: true

barrier cell
type: Class
subclass of: cell
definition: A cell whose primary function is to prevent the transport of stuff across compartments.

Axiom
annotated source: barrier cell
annotated property: definition
annotated target: A cell whose primary function is to prevent the transport of stuff across compartments.
database_cross_reference: JB:jb

motile cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0048870
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0048870
definition: A cell that moves by its own activities.

Axiom
annotated source: motile cell
annotated property: definition
annotated target: A cell that moves by its own activities.
database_cross_reference: FB:ma

ectodermal cell
type: Class
subclass of: CL_0002321
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000924
definition: A cell of the outer of the three germ layers of the embryo.
database_cross_reference: FMA:72549
has_exact_synonym: ectoderm cell

Axiom
annotated source: ectodermal cell
annotated property: definition
annotated target: A cell of the outer of the three germ layers of the embryo.
database_cross_reference: MESH:D004475

mesodermal cell
type: Class
subclass of: CL_0002321
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000926
definition: A cell of the middle germ layer of the embryo.
database_cross_reference: FMA:72554
has_exact_synonym: mesoblast
has_exact_synonym: mesoderm cell
in_subset: cellxgene subset

Axiom
annotated source: mesodermal cell
annotated property: definition
annotated target: A cell of the middle germ layer of the embryo.
database_cross_reference: MESH:D008648

endodermal cell
type: Class
subclass of: CL_0002321
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000925
definition: A cell of the inner of the three germ layers of the embryo.
database_cross_reference: FMA:72555
has_exact_synonym: endoderm cell

Axiom
annotated source: endodermal cell
annotated property: definition
annotated target: A cell of the inner of the three germ layers of the embryo.
database_cross_reference: MESH:D004707

anucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001405
subclass of: cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001405
disjoint with: CL_0002242
definition: A cell that lacks a nucleus.
database_cross_reference: FMA:68647
has_exact_synonym: non-nucleated cell

Axiom
annotated source: anucleate cell
annotated property: definition
annotated target: A cell that lacks a nucleus.
database_cross_reference: FB:ma

single nucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001407
subclass of: CL_0002242
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001407
definition: A cell with a single nucleus.

Axiom
annotated source: single nucleate cell
annotated property: definition
annotated target: A cell with a single nucleus.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm

binucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001406
subclass of: multinucleate cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001406

multinucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001908
subclass of: CL_0002242
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001908
definition: A cell with more than one nucleus.
database_cross_reference: AEO:0000203
database_cross_reference: WBbt:0008074
has_exact_synonym: syncitium
has_exact_synonym: syncytial cell
has_exact_synonym: syncytium

Axiom
annotated source: multinucleate cell
annotated property: definition
annotated target: A cell with more than one nucleus.
database_cross_reference: FB:ma

erythrocyte
type: Class
equivalent class: Class
  intersection of: CL_0000764
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0005840
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001945
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0002039
  intersection of: Restriction
    on property: capable of
    some values from: GO_0008015
  intersection of: Restriction
    on property: capable of
    some values from: GO_0015671
subclass of: blood cell
subclass of: oxygen accumulating cell
subclass of: CL_0000764
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0005840
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001945
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002039
subclass of: Restriction
  on property: develops from
  some values from: CL_0000558
subclass of: Restriction
  on property: capable of
  some values from: GO_0008015
subclass of: Restriction
  on property: capable of
  some values from: GO_0015671
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
present in taxon: NCBITaxon 9606
database_cross_reference: BTO:0000424
database_cross_reference: CALOHA:TS-0290
database_cross_reference: FMA:81100
has_exact_synonym: RBC
has_exact_synonym: red blood cell
in_subset: blood and immune upper slim
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: erythrocyte
annotated property: subClassOf
annotated target: CL_0000764
is inferred: true

Axiom
annotated source: erythrocyte
annotated property: definition
annotated target: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D004912

eukaryotic cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: only in taxon
    some values from: NCBITaxon 2759
subclass of: cell
subclass of: Restriction
  on property: only in taxon
  some values from: NCBITaxon 2759
database_cross_reference: MESH:D005057
in_subset: cellxgene subset

Eumycetozoan cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: only in taxon
    some values from: NCBITaxon_142796
subclass of: eukaryotic cell
subclass of: Restriction
  on property: only in taxon
  some values from: NCBITaxon_142796

eye photoreceptor cell
type: Class
equivalent class: Class
  intersection of: photoreceptor cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000970
subclass of: photoreceptor cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000970
present in taxon: NCBITaxon 9606
in_subset: cellxgene subset
in_subset: eye upper slim
in_subset: human reference atlas

structural cell
type: Class
subclass of: cell
definition: A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.

Axiom
annotated source: structural cell
annotated property: definition
annotated target: A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.
database_cross_reference: TAIR:sr

gamete
type: Class
equivalent class: Class
  intersection of: CL_0000586
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001375
  intersection of: Restriction
    on property: capable of
    some values from: GO_0009566
subclass of: haploid cell
subclass of: CL_0000586
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001375
subclass of: Restriction
  on property: capable of
  some values from: GO_0009566
definition: A mature sexual reproductive cell having a single set of unpaired chromosomes.
database_cross_reference: CALOHA:TS-0395
database_cross_reference: FBbt:00005412
database_cross_reference: FMA:18649
has_exact_synonym: haploid nucleated cell
has_related_synonym: haploid germ cell

Axiom
annotated source: gamete
annotated property: subClassOf
annotated target: CL_0000586
is inferred: true

Axiom
annotated source: gamete
annotated property: definition
annotated target: A mature sexual reproductive cell having a single set of unpaired chromosomes.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544

crystallin accumulating cell
type: Class
subclass of: stuff accumulating cell
has_exact_synonym: lens cell
in_subset: eye upper slim

serous secreting cell
type: Class
subclass of: seromucus secreting cell
definition: Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid.
database_cross_reference: BTO:0003687
database_cross_reference: FMA:62511
has_exact_synonym: serous cell
in_subset: cellxgene subset

Axiom
annotated source: serous secreting cell
annotated property: definition
annotated target: Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0517223651
database_cross_reference: ISBN:0721662544

mucus secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0070254
subclass of: seromucus secreting cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0070254
database_cross_reference: BTO:0003689
has_exact_synonym: mucous cell
in_subset: cellxgene subset

stuff accumulating cell
type: Class
subclass of: cell
definition: A cell that is specialised to accumulate a particular substance(s).
in_subset: upper level

Axiom
annotated source: stuff accumulating cell
annotated property: definition
annotated target: A cell that is specialised to accumulate a particular substance(s).
database_cross_reference: FB:ma

extracellular matrix secreting cell
type: Class
subclass of: CL_0000499

oxygen accumulating cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: capable of
    some values from: GO_0015671
subclass of: cell
subclass of: Restriction
  on property: capable of
  some values from: GO_0015671

migratory neural crest cell
type: Class
subclass of: motile cell
subclass of: CL_0011012
subclass of: CL_0011026
subclass of: UBERON_0010313
subclass of: Restriction
  on property: develops from
  some values from: CL_0007004
definition: A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.
database_cross_reference: FMA:86667

Axiom
annotated source: migratory neural crest cell
annotated property: definition
annotated target: A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.
database_cross_reference: doi:10.1016/j.stem.2015.02.017

mesenchyme condensation cell
type: Class
subclass of: CL_0008019
definition: A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.

Axiom
annotated source: mesenchyme condensation cell
annotated property: definition
annotated target: A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:5025404

scleral cell
type: Class
equivalent class: Class
  intersection of: structural cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001773
subclass of: structural cell
subclass of: UBERON_0010313
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001773
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
definition: A cell of the sclera of the eye.
in_subset: eye upper slim

Axiom
annotated source: scleral cell
annotated property: definition
annotated target: A cell of the sclera of the eye.
database_cross_reference: GOC:add

choroidal cell of the eye
type: Class
equivalent class: Class
  intersection of: structural cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001776
subclass of: structural cell
subclass of: UBERON_0010313
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001776
subclass of: Restriction
  on property: develops from
  some values from: migratory cranial neural crest cell
definition: A structural cell that is part of optic choroid.
in_subset: eye upper slim

Axiom
annotated source: choroidal cell of the eye
annotated property: definition
annotated target: A structural cell that is part of optic choroid.
database_cross_reference: GOC:add

extraembryonic cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0000478
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000478
in_subset: general cell types upper slim

trophoblast cell
type: Class
subclass of: extraembryonic cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0000358
definition: A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface.
database_cross_reference: FMA:83028
has_exact_synonym: trophoblastic cell

Axiom
annotated source: trophoblast cell
annotated property: subClassOf
annotated target: extraembryonic cell
is inferred: true

Axiom
annotated source: trophoblast cell
annotated property: definition
annotated target: A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:D014327

epiblast cell
type: Class
subclass of: totipotent stem cell
definition: A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation.

Axiom
annotated source: epiblast cell
annotated property: definition
annotated target: A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256

blastoderm cell
type: Class
subclass of: early embryonic cell (metazoa)
definition: An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).
database_cross_reference: BTO:0001473
database_cross_reference: FMA:72551
has_exact_synonym: blastomere

Axiom
annotated source: blastoderm cell
annotated property: definition
annotated target: An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).
database_cross_reference: MESH:D001756

multi-potent skeletal muscle stem cell
type: Class
equivalent class: Class
  intersection of: multi fate stem cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0001134
subclass of: multi fate stem cell
subclass of: cell of skeletal muscle
subclass of: Restriction
  on property: part of
  some values from: UBERON_0001134
definition: A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell.
database_cross_reference: FMA:86767
comment: Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo.

Axiom
annotated source: multi-potent skeletal muscle stem cell
annotated property: subClassOf
annotated target: multi fate stem cell
is inferred: true

Axiom
annotated source: multi-potent skeletal muscle stem cell
annotated property: definition
annotated target: A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell.
database_cross_reference: PMID:18282570

sphincter associated smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0004590
subclass of: smooth muscle cell
subclass of: Restriction
  on property: part of
  some values from: UBERON_0004590
definition: A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.

Axiom
annotated source: sphincter associated smooth muscle cell
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: sphincter associated smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.
database_cross_reference: GOC:cjm

vascular associated smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0002049
subclass of: smooth muscle cell
subclass of: CL_4033054
subclass of: Restriction
  on property: part of
  some values from: UBERON_0002049
definition: A smooth muscle cell associated with the vasculature.
present in taxon: NCBITaxon 9606
has_exact_synonym: VSMC
has_exact_synonym: vascular smooth muscle cell
in_subset: cellxgene subset
in_subset: human reference atlas

Axiom
annotated source: vascular associated smooth muscle cell
annotated property: subClassOf
annotated target: smooth muscle cell
is inferred: true

Axiom
annotated source: vascular associated smooth muscle cell
annotated property: definition
annotated target: A smooth muscle cell associated with the vasculature.
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm

epidermal cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: part of
    some values from: UBERON_0007376
subclass of: CL_0002159
subclass of: Restriction
  on property: part of
  some values from: UBERON_0007376
definition: An epithelial cell of the integument (the outer layer of an organism).
database_cross_reference: BTO:0001470
database_cross_reference: CALOHA:TS-0283
database_cross_reference: FMA:62411
database_cross_reference: MESH:D000078404
has_exact_synonym: cell of epidermis
has_narrow_synonym: epithelial cell of skin
in_subset: cellxgene subset

Axiom
annotated source: epidermal cell
annotated property: definition
annotated target: An epithelial cell of the integument (the outer layer of an organism).
database_cross_reference: Flybase:dsj
database_cross_reference: MA:ma

Axiom
annotated source: epidermal cell
annotated property: has_exact_synonym
annotated target: cell of epidermis
database_cross_reference: FMA:62411

Axiom
annotated source: epidermal cell
annotated property: has_narrow_synonym
annotated target: epithelial cell of skin
database_cross_reference: FMA:62411

animal zygote
type: Class
equivalent class: Class
  intersection of: CL_0010017
  intersection of: Restriction
    on property: only in taxon
    some values from: NCBITaxon_33208
subclass of: early embryonic cell (metazoa)
subclass of: eukaryotic cell
subclass of: CL_0010017
subclass of: Restriction
  on property: only in taxon
  some values from: NCBITaxon_33208
definition: Diploid cell produced by the fusion of sperm cell nucleus and egg cell.
has_broad_synonym: zygote
database_cross_reference: BTO:0000854
database_cross_reference: EHDAA2:0004546
database_cross_reference: FMA:72395

Axiom
annotated source: animal zygote
annotated property: definition
annotated target: Diploid cell produced by the fusion of sperm cell nucleus and egg cell.
database_cross_reference: ISBN:0471245208

electrically responsive cell
type: Class
subclass of: electrically active cell
definition: A cell whose function is determined by its response to an electric signal.

Axiom
annotated source: electrically responsive cell
annotated property: definition
annotated target: A cell whose function is determined by its response to an electric signal.
database_cross_reference: FB:ma

ganglion interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0000045
subclass of: interneuron
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0000045
in_subset: cellxgene subset

Axiom
annotated source: ganglion interneuron
annotated property: subClassOf
annotated target: interneuron
is inferred: true

CNS interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: has soma location
    some values from: UBERON_0001017
subclass of: interneuron
subclass of: CL_2000029
subclass of: Restriction
  on property: has soma location
  some values from: UBERON_0001017
definition: An interneuron that has its cell body in a central nervous system.
present in taxon: NCBITaxon 9606
in_subset: human reference atlas
comment: Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system.

Axiom
annotated source: CNS interneuron
annotated property: definition
annotated target: An interneuron that has its cell body in a central nervous system.
database_cross_reference: doi:10.1016/B978-0-12-817424-1.00001-X

electrically signaling cell
type: Class
subclass of: electrically active cell
definition: A cell that initiates an electrical signal and passes that signal to another cell.

Axiom
annotated source: electrically signaling cell
annotated property: definition
annotated target: A cell that initiates an electrical signal and passes that signal to another cell.
database_cross_reference: FB:ma

polyploid cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0001377
subclass of: cell
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0001377
definition: A cell that contains more than two haploid sets of chromosomes.

Axiom
annotated source: polyploid cell
annotated property: definition
annotated target: A cell that contains more than two haploid sets of chromosomes.
database_cross_reference: FB:ma
database_cross_reference: PMID:32646579
database_cross_reference: https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy

haploid cell
type: Class
equivalent class: Class
  intersection of: cell
subclass of: cell
definition: A cell whose nucleus contains a single haploid genome.