diseaseId,targetId_genename,targetId,targetFromSourceId,Max Completed Clinical Phase,Associated drugId(s),drugbank,Target/Enzyme/Transporter,Pharmacological action,Therapeutic Intent,Notes
MONDO_0004975,CD38,ENSG00000004468,P28907,2,CHEMBL1743007,,,Inhibitor,Disease-modifying,
MONDO_0004975,SCN4A,ENSG00000007314,P35499,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,GABRA3,ENSG00000011677,P34903,2,CHEMBL2107801,,,Inverse agonist,Disease-modifying,
MONDO_0004975,GABRA1,ENSG00000022355,P14867,2,CHEMBL2107801,,,Inverse agonist,Disease-modifying,
MONDO_0004975,FGFR3,ENSG00000068078,P22607,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0004975,MAOB,ENSG00000069535,P27338,2,CHEMBL887,DB01367,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,RARB,ENSG00000077092,P10826,2,CHEMBL1131,DB00459,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,DRD4,ENSG00000069696,P21917,3,"CHEMBL301265, CHEMBL1303, CHEMBL54","DB00413, DB05271, DB00502",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Both,(DB00413 is DMT investigation)
MONDO_0004975,PTGS2,ENSG00000073756,P35354,3,"CHEMBL6, CHEMBL118, CHEMBL122, CHEMBL154","DB00328, DB00482, DB00533, DB00788",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,CACNA1S,ENSG00000081248,Q13698,3,CHEMBL517427,DB06712,Target,Inhibitor,Disease-modifying,(Did not benefit patients)
MONDO_0004975,CACNA1F,ENSG00000102001,O60840,3,CHEMBL517427,DB06712,,,Disease-modifying,(Did not benefit patients)
MONDO_0004975,GABRG2,ENSG00000113327,P18507,2,CHEMBL2107801,,,Inverse agonist,Disease-modifying,
MONDO_0004975,PDGFRB,ENSG00000113721,P09619,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0004975,PDGFRA,ENSG00000134853,P16234,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0004975,SCN2A,ENSG00000136531,Q99250,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,SCN7A,ENSG00000136546,Q01118,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,PSEN1,ENSG00000080815,P49768,3,"CHEMBL520733, CHEMBL1090771, CHEMBL190083","DB12463, DB11893, DB05289",Target,Modulator,Both,(DB05289 is DMT; DB12463 worsened clinical outcomes)
MONDO_0004975,PGR,ENSG00000082175,P06401,2,"CHEMBL717, CHEMBL103","DB00603, DB00396",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,GSK3B,ENSG00000082701,P49841,2,"CHEMBL1200826, CHEMBL3545157","DB14509, DB12129",Target,Unknown,Both,(DB12129 in DMT)
MONDO_0004975,CETP,ENSG00000087237,P11597,2,CHEMBL3785197,DB14890,Target,Inhibitor,Disease-modifying,
MONDO_0004975,ESR1,ENSG00000091831,P03372,3,"CHEMBL135, CHEMBL1201649	",DB00783,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,RARA,ENSG00000131759,P10276,2,CHEMBL1131,DB00459,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,ACHE,ENSG00000087085,P22303,4,"CHEMBL659, CHEMBL1678, CHEMBL636, CHEMBL502, CHEMBL1555, CHEMBL1255901               ","DB00674, DB00989, DB00843",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,[suggested CHEMBL1255901 has DMT properties]
MONDO_0004975,PTGS1,ENSG00000095303,P23219,2,"CHEMBL154, CHEMBL6","DB00788, DB00328",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,ABL1,ENSG00000097007,P00519,3,"CHEMBL255863, CHEMBL217092","DB04868, DB11805",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,BCHE,ENSG00000114200,P06276,4,CHEMBL636,DB00989,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0004975,SCN1A,ENSG00000144285,P35498,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,HRH3,ENSG00000101180,Q9Y5N1,2,"CHEMBL476323, CHEMBL3545029, CHEMBL3092650","DB11910, DB15120",Target,Agonist,Both,(DB15120 is DMT)
MONDO_0004975,CHRNA4,ENSG00000101204,P43681,2,"CHEMBL188462, CHEMBL1076903, CHEMBL2179529	",DB16205,Target,Modulator,Symptomatic,
MONDO_0004975,SRC,ENSG00000197122,P12931,2,CHEMBL217092,DB11805,Target,Modulator,Disease-modifying,
MONDO_0004975,CACNA1D,ENSG00000157388,Q01668,3,CHEMBL517427,DB06712,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,KIT,ENSG00000157404,P10721,3,CHEMBL1908391,DB11526,,Inhibitor,Disease-modifying,
MONDO_0004975,HTR2A,ENSG00000102468,P28223,3,"CHEMBL54, CHEMBL85, CHEMBL1112, CHEMBL2105760, CHEMBL2448613, CHEMBL2111101, CHEMBL621","DB00502, DB00734, DB01238, DB09128, DB05316, DB00656",Target,Antagonist,Symptomatic,
MONDO_0004975,SLC6A2,ENSG00000103546,P23975,3,"CHEMBL641, CHEMBL796, CHEMBL3989690, CHEMBL1702        ","DB00289, DB00422, DB06156",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Both,"DB00289, DB00422, CHEMBL1702 is DMT"
MONDO_0004975,SLC6A4,ENSG00000108576,P31645,3,"CHEMBL621, CHEMBL3989690","DB00656, DB06156",Target,Uknown,Symptomatic,
MONDO_0004975,SCN8A,ENSG00000196876,Q9UQD0,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,GSK3A,ENSG00000105723,P49840,2,CHEMBL1200826,DB14509,Target,Inhibitor,Disease-modifying,
MONDO_0004975,VDR,ENSG00000111424,P11473,3,CHEMBL1536,DB00153,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,PPARD,ENSG00000112033,Q03181,2,CHEMBL3545176,,,,Disease-modifying,
MONDO_0004975,GRIN2D,ENSG00000105464,O15399,4,"CHEMBL807, CHEMBL2110954, CHEMBL1699	","DB01043, DB04926",,,Symptomatic,
MONDO_0004975,GNRHR,ENSG00000109163,P30968,2,"CHEMBL1201199, CHEMBL1200775	",DB00007,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,MAPK14,ENSG00000112062,Q16539,2,CHEMBL119385,DB07138,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,ALDH5A1,ENSG00000112294,P51649,3,"CHEMBL109, CHEMBL2105613        ",DB00313,Target,Inhibitor,Symptomatic,
MONDO_0004975,HMGCR,ENSG00000113161,P04035,3,"CHEMBL1064, CHEMBL1487, CHEMBL393220	","DB00641, DB01076",Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,NR3C1,ENSG00000113580,P04150,3,CHEMBL635,DB00635,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,GRIN3B,ENSG00000116032,O60391,3,"CHEMBL807, CHEMBL1699",DB01043,,,Symptomatic,
MONDO_0004975,APH1A,ENSG00000117362,Q96BI3,3,"CHEMBL520733, CHEMBL1090771, CHEMBL190083","DB12463, DB11893, DB05289",Target,Modulator,Disease-modifying,(DB12463 worsened clinical outcomes)
MONDO_0004975,HSD11B1,ENSG00000117594,P28845,2,CHEMBL4297256,,,Inhibitor,Symptomatic,
MONDO_0004975,CNR1,ENSG00000118432,P21554,2,CHEMBL465,DB00470,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0004975,GRIA2,ENSG00000120251,P42262,2,CHEMBL1277001,DB12717,,Positive allosteric modulator,Symptomatic,
MONDO_0004975,GRIA3,ENSG00000125675,P42263,2,CHEMBL1277001,DB12717,,Positive allosteric modulator,Symptomatic,
MONDO_0004975,ADORA2A,ENSG00000128271,P29274,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0004975,IMPA1,ENSG00000133731,P29218,2,CHEMBL1200826,DB14509,Target,Unknown,Disease-modifying,
MONDO_0004975,MMP8,ENSG00000118113,P22894,3,"CHEMBL1433, CHEMBL1200699        ",DB00254,,Inhibitor,Disease-modifying,
MONDO_0004975,CHRNA10,ENSG00000129749,Q9GZZ6,3,CHEMBL2110954,DB04926,,Antagonist,Symptomatic,
MONDO_0004975,CHRM3,ENSG00000133019,P20309,2,CHEMBL2111051,DB12287,,Partial agonist,Symptomatic,
MONDO_0004975,MTNR1B,ENSG00000134640,P49286,2,CHEMBL4297523,DB12288,,,Disease-modifying,
MONDO_0004975,SCN11A,ENSG00000168356,Q9UI33,2,CHEMBL744,DB00740,Target,Blocker,Disease-modifying,
MONDO_0004975,MTNR1A,ENSG00000168412,P48039,2,CHEMBL4297523,DB12288,Target,Agonist,Disease-modifying,
MONDO_0004975,PPARG,ENSG00000132170,P37231,3,"CHEMBL121, CHEMBL595","DB00412, DB01132",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,(DB00412 not positive results)
MONDO_0004975,CHRM1,ENSG00000168539,P11229,2,CHEMBL2111051,DB12287,,Agonist,Symptomatic,
MONDO_0004975,SCN9A,ENSG00000169432,Q15858,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,ADORA2B,ENSG00000170425,P29275,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0004975,BCR,ENSG00000186716,P11274,3,CHEMBL255863,DB04868,Target (BCR-ABL fusion protein),,Disease-modifying,
MONDO_0004975,GABBR2,ENSG00000136928,O75899,2,CHEMBL112797,DB05010,Target,Modulator,Disease-modifying,
MONDO_0004975,HCRTR2,ENSG00000137252,O43614,2,CHEMBL3597971,,,Antagonist,Symptomatic,
MONDO_0004975,MMP7,ENSG00000137673,P09237,3,"CHEMBL1433, CHEMBL1200699	",DB00254,,Inhibitor,Disease-modifying,
MONDO_0004975,MMP13,ENSG00000137745,P45452,3,"CHEMBL1433, CHEMBL1200699	",DB00254,,Inhibitor,Disease-modifying,
MONDO_0004975,MMP1,ENSG00000196611,P03956,3,"CHEMBL1433, CHEMBL1200699	",DB00254,,Inhibitor,Disease-modifying,
MONDO_0004975,APH1B,ENSG00000138613,Q8WW43,3,"CHEMBL190083, CHEMBL520733, CHEMBL1090771","DB05289, DB12463, DB11893",Target,Modulator,Disease-modifying,(DB12463 worsened clinical outcomes)
MONDO_0004975,PDE5A,ENSG00000138735,O76074,3,CHEMBL2103849,DB06267,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,ESR2,ENSG00000140009,Q92731,3,"CHEMBL81, CHEMBL1201649	",DB00481,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,IFNAR1,ENSG00000142166,P17181,2,CHEMBL1201562,,,Agonist,Disease-modifying,
MONDO_0004975,PSEN2,ENSG00000143801,P49810,3,"CHEMBL190083, CHEMBL520733, CHEMBL1090771","DB05289, DB12463, DB11893",Target,Inhibitor,Disease-modifying,(DB12463 worsened clinical outcomes)
MONDO_0004975,APP,ENSG00000142192,P05067,3,"CHEMBL149082, CHEMBL2108058, CHEMBL1743025, CHEMBL1743072, CHEMBL1743004, CHEMBL2108576, CHEMBL4650301 , CHEMBL3039540, CHEMBL1743058, CHEMBL3833321, CHEMBL4297245, CHEMBL2108328        ",DB06527,Target,Antagonist,Disease-modifying,(DB06527 considered failure)
MONDO_0004975,SLC6A3,ENSG00000142319,Q01959,2,"CHEMBL3989690, CHEMBL796, CHEMBL1373","DB06156, DB00422, DB00745",Target,Unknown,Symptomatic,
MONDO_0004975,RXRG,ENSG00000143171,P48443,2,"CHEMBL1131, CHEMBL1023","DB00459, DB00307",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,PLA2G7,ENSG00000146070,Q13093,2,CHEMBL2104981,DB05119,Target,Inhibitor,Disease-modifying,
MONDO_0004975,HTR2C,ENSG00000147246,P28335,3,"CHEMBL85, CHEMBL621","DB00734, DB00656",Target,Antagonist,Symptomatic,
MONDO_0004975,CACNA1B,ENSG00000148408,Q00975,2,CHEMBL1286,DB01202,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,DRD2,ENSG00000149295,P14416,3,"CHEMBL85, CHEMBL301265, CHEMBL1112, CHEMBL54, CHEMBL1303, CHEMBL1378, CHEMBL2105760","DB00734, DB00413, DB01238, DB00502, DB05271, DB00372, DB09128",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Both,(DB00413 is DMT)
MONDO_0004975,CACNA1C,ENSG00000151067,Q13936,3,CHEMBL517427,DB06712,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,(Did not benefit patients)
MONDO_0004975,DRD3,ENSG00000151577,P35462,3,"CHEMBL301265, CHEMBL1303, CHEMBL54","DB00413, DB05271, DB00502",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Both,(DB00413 is DMT)
MONDO_0004975,GABRA2,ENSG00000151834,P47869,2,CHEMBL2107801,,,Inverse agonist,Disease-modifying,
MONDO_0004975,GRIA4,ENSG00000152578,P48058,2,CHEMBL1277001,DB12717,,Positive allosteric modulator,Symptomatic,
MONDO_0004975,SCN3A,ENSG00000153253,Q9NY46,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,GRIA1,ENSG00000155511,P42261,2,CHEMBL1277001,DB12717,,Positive allosteric modulator,Symptomatic,
MONDO_0004975,GRIN2C,ENSG00000161509,Q14957,4,"CHEMBL807, CHEMBL2110954, CHEMBL1699	","DB01043, DB04926",,,Symptomatic,
MONDO_0004975,HTR3B,ENSG00000149305,O95264,2,"CHEMBL2151439, CHEMBL5095032        ",DB05586,,Antagonist,Symptomatic,
MONDO_0004975,IFNAR2,ENSG00000159110,P48551,2,CHEMBL1201562,,,Agonist,Disease-modifying,
MONDO_0004975,SV2A,ENSG00000159164,Q7L0J3,2,CHEMBL1286,DB01202,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,GABRG1,ENSG00000163285,Q8N1C3,2,CHEMBL2107801,,,Inverse agonist,Disease-modifying,
MONDO_0004975,ADORA1,ENSG00000163485,P30542,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0004975,HTR6,ENSG00000158748,P50406,4,"CHEMBL1083390, CHEMBL3286580, CHEMBL4117187, CHEMBL2103880","DB12680, DB11957, DB06140, DB12229",Target,Antagonist,Both,(CHEMBL4117187 and DB12229 potentially DMT)
MONDO_0004975,CHRNB2,ENSG00000160716,P17787,2,"CHEMBL188462, CHEMBL1076903, CHEMBL2179529	",DB16205,Target,Modulator,Symptomatic,
MONDO_0004975,PDE9A,ENSG00000160191,O76083,2,"CHEMBL2179105, CHEMBL4206492","DB11953, DB16274",Target,Inhibitor,Both,(DB16274 potential DMT)
MONDO_0004975,NCSTN,ENSG00000162736,Q92542,3,"CHEMBL520733, CHEMBL190083, CHEMBL1090771","DB12463, DB05289, DB11893",Target,Modulator,Disease-modifying,(DB12463 worsened clinical outcomes)
MONDO_0004975,HTR3A,ENSG00000166736,P46098,2,"CHEMBL2151439, CHEMBL5095032	",DB05586,,Antagonist,Symptomatic,
MONDO_0004975,HTR4,ENSG00000164270,Q13639,2,CHEMBL3306918,DB05596,,Partial agonist,Symptomatic,
MONDO_0004975,GABRB3,ENSG00000166206,P28472,2,CHEMBL356388,,,Positive allosteric modulator,Disease-modifying,
MONDO_0004975,RARG,ENSG00000172819,P13631,2,CHEMBL1131,DB00459,Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,GRIN1,ENSG00000176884,Q05586,4,"CHEMBL807, CHEMBL1699, CHEMBL2110954","DB01043, DB04926",Target,,Symptomatic,
MONDO_0004975,HTR3C,ENSG00000178084,Q8WXA8,2,"CHEMBL2151439, CHEMBL5095032	",DB05586,,Antagonist,Symptomatic,
MONDO_0004975,CHRM2,ENSG00000181072,P08172,2,CHEMBL2111051,DB12287,,Partial agonist,Symptomatic,
MONDO_0004975,GABRG3,ENSG00000182256,Q99928,2,CHEMBL2107801,,,Inverse agonist,Disease-modifying,
MONDO_0004975,RXRA,ENSG00000186350,P19793,2,"CHEMBL1023, CHEMBL1131","DB00307, DB00459",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,PAH,ENSG00000171759,P00439,2,CHEMBL1201774,DB00360,Target,Cofactor: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0004975,INSR,ENSG00000171105,P06213,2,CHEMBL1201613,,,Agonist,Disease-modifying,
MONDO_0004975,CYSLTR1,ENSG00000173198,Q9Y271,2,CHEMBL787,DB00471,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,CHRNA9,ENSG00000174343,Q9UGM1,3,CHEMBL2110954,DB04926,,,Symptomatic,
MONDO_0004975,CHRNA7,ENSG00000175344,P36544,2,"CHEMBL2151439, CHEMBL5095032, CHEMBL134713, CHEMBL2151572, CHEMBL3545231        ","DB05586, DB05708, DB11726",Target,Antagonist,Symptomatic,
MONDO_0004975,HTR1A,ENSG00000178394,P08908,3,"CHEMBL1112, CHEMBL2105760, CHEMBL372205, CHEMBL1512580, CHEMBL2107349        ","DB01238, DB09128, DB12540, DB06393, DB04888",Target,Partial agonist,Both,(CHEMBL1512580 and DB04888 for DMT)
MONDO_0004975,GRIN2A,ENSG00000183454,Q12879,4,"CHEMBL807, CHEMBL1699, CHEMBL2110954","DB01043, DB04926",,,Symptomatic,
MONDO_0004975,SCN5A,ENSG00000183873,Q14524,2,CHEMBL744,DB00740,Target,Inhibitor: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,SCN10A,ENSG00000185313,Q9Y5Y9,2,CHEMBL744,DB00740,,,Disease-modifying,
MONDO_0004975,HTR3E,ENSG00000186038,A5X5Y0,2,"CHEMBL2151439, CHEMBL5095032	",DB05586,,Antagonist,Symptomatic,
MONDO_0004975,HTR3D,ENSG00000186090,Q70Z44,2,"CHEMBL2151439, CHEMBL5095032	",DB05586,,Antagonist,Symptomatic,
MONDO_0004975,GABRA5,ENSG00000186297,P31644,2,CHEMBL2107801,,,Inverse agonist,Disease-modifying,
MONDO_0004975,RXRB,ENSG00000204231,P28702,2,"CHEMBL1023, CHEMBL1131","DB00307, DB00459",Target,Agonist: Drug interacts directly with the target as part of its mechanism of action,Disease-modifying,
MONDO_0004975,ADRA2C,ENSG00000184160,P18825,2,CHEMBL4297312,DB12057,Target,Antagonist,Symptomatic,
MONDO_0004975,BACE1,ENSG00000186318,P56817,3,"CHEMBL3989948, CHEMBL3916243, CHEMBL4204869","DB14814, DB15307, DB15391",Target,Inhibitor,Disease-modifying,
MONDO_0004975,GRIN3A,ENSG00000198785,Q8TCU5,4,"CHEMBL2110954, CHEMBL1699 CHEMBL807","DB04926, DB01043",Target,Unknown,Symptomatic,
MONDO_0004975,GRIN2B,ENSG00000273079,Q13224,4,"CHEMBL2110954, CHEMBL1699 CHEMBL807","DB04926, DB01043",,,Symptomatic,
MONDO_0004975,ADORA3,ENSG00000282608,P0DMS8,3,CHEMBL113,DB00201,Target,Antagonist: Drug interacts directly with the target as part of its mechanism of action,Symptomatic,
MONDO_0004975,GABBR1,ENSG00000204681,Q9UBS5,2,CHEMBL112797,DB05010,Target,Modulator,Symptomatic,
MONDO_0004975,FLNA,ENSG00000196924,P21333,3,CHEMBL4650230,,,Positive modulator,Disease-modifying,
MONDO_0004975,AGER,ENSG00000204305,Q15109,3,CHEMBL3989929,DB12689,Target,Antagonist,Disease-modifying,
MONDO_0004975,MAPT,ENSG00000186868,P10636,2,"CHEMBL4298021, CHEMBL4297860        ",,,Inhibitor,Disease-modifying,
MONDO_0004975,PSENEN,ENSG00000205155,Q9NZ42,3,"CHEMBL520733, CHEMBL190083, CHEMBL1090771","DB12463, DB05289, DB11893",Target,Modulator,Disease-modifying,(DB12463 worsened clinical outcomes)
MONDO_0004975,TNF,ENSG00000232810,P01375,2,CHEMBL1201572,,,Inhibitor,Disease-modifying,